The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial inner membrane, mitochondrial matrix", "input_participant_list": [ "R-ALL-880013" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZGL8-1" ], "evidence": [ { "id": "R-GGA-880050", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-880050" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-880013", "participant_name": "(S)-2HG [mitochondrial matrix]", "crossref": [ { "id": "16782", "database": "ChEBI", "url": "" }, { "id": "5460355", "database": "PubChem Compound", "url": "" }, { "id": "C03196", "database": "KEGG Gene", "url": "" }, { "id": "13095-48-2", "database": "CAS", "url": "" }, { "id": "CPD-381", "database": "AraCyc", "url": "" }, { "id": "ZINC000000402967", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZGL8", "gene_name": "L2HGDH", "activity": [ { "ec_number": "1.1.99.2", "activity": "(S)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2.", "evidence": [ { "id": "A0A8V0ZGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGL8" } ] }, { "ec_number": "1.1.99.2", "activity": "", "evidence": [ { "id": "A0A8V0ZGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGL8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGL8" }, { "id": "PF01266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAD dependent oxidoreductase", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 434, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.99.2", "ec_name": "(S)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2.", "evidence": [ { "id": "1.1.99.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.99.2" }, { "id": "1.1.99.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.99.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 343, "end_pos": 345 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGC2-1", "uniprot_ac": "A0A8V0ZGC2", "uniprot_id": "A0A8V0ZGC2_CHICK", "mass": { "chemical_mass": 171020.0, "monoisotopic_mass": 171020.0 }, "refseq": { "ac": "XP_015131158", "name": "golgin subfamily A member 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131158" }, "gene_names": [ { "name": "GOLGA3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2" } ] }, { "name": "GOLGA3", "type": "synonym", "evidence": [ { "id": "XP_015131158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131158" } ] } ], "protein_names": [ { "name": "Golgin A3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2/entry#names_and_taxonomy" } ] }, { "name": "golgin subfamily A member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015131158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131158" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015131158.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015131158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131158" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GOLGA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2", "locus": { "chromosome": "15", "start_pos": 1466900, "end_pos": 1508808, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021102", "url": "https://www.ensembl.org/id/ENSGALG00010021102" } ] } } ], "crossref": [ { "id": "416791", "url": "https://www.ncbi.nlm.nih.gov/gene/416791", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416791", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416791", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDDQHAQ", "url": "https://omabrowser.org/oma/group/QDDQHAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAP0", "url": "https://www.orthodb.org/?gene=A0A8V0ZAP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGC2", "url": "https://www.orthodb.org/?gene=A0A8V0ZGC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGE2", "url": "https://www.orthodb.org/?gene=A0A8V0ZGE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHI7", "url": "https://www.orthodb.org/?gene=A0A8V0ZHI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18902:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18902:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015131158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015131158", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESSSVQQDVLLDNRSSSGAPGTSQEHGDCNANSALPATGDEVNTSSVNLSEVPNEEGSLELNSKADACQNGPELLFPDSPISFDPTSSPQGQESSPGVPGFHDSLRKSQGTSAEGVALRKEALQSLKLSLPMQETELCSVESSLPLENEEQIRLQARRRLEEQLRQYRVKRHQERSNQSTSKSRPSSTLDPELMLNPEILPRASTVAMTKEYSFLRTSVPRGPKLGSLGLPASSKERKSSKSSKSSKIRSLADYRTEDSGSGSSAGNLMATDLPGGTLKQSRSGPASVVSEISLPFDTDDRIENSSLAGDSISEIDGSEAGMRLDGNESDSSTYSSVSGKGLCNNLPNSEGKERIPYTINGQKIHPDAIGQFPSISEVLQAAAVEHQAQEQEFNGEIRSRRDSISSSVSMESSVAGTHDEMLQVLKEKMRLEGQLEALSAEANQALKEKAELQAQLAALNMKLQAQVEHSQSSQQKQESLSSEVATLKQSCWDLERAMADLQNTLEAKNASLASSNNDLQLAEEQYQRLMLKVEDMQKSVLTRDSTVHDLRQQLASLQSQLQKVQLERTTLTNKLKASETEITSLQNVRQWYQQQLVLAQEARVRLQSEMANIQAGQMTQAGVLEHLKLENVALSQQLTETQHRSIKEKERIAAQLQNIEADMLDQEAAFMQIQEAKTMVEEDLQRKLEEFEDEKEQLQKMADSAATLEQELDQVKLTLHQRDLQLESLQQEHLDLMKQFTMTQEMLHTKEQTLDDLQTQYDELKARLEEFQSDATSKDDMIQYLQNEKIVLEVALQTAKASQDQLDEGTKRLGEDTEVTSEILEQLRQEMAIRSSQVENLQQENGSLKKQVQKVKEQFLQQKVMVEAYRRDASSKDQLISELKATKKRLDSEMKELKRELLQIQVEKQSLETEHSKLQKEVTEVHQQMVEIENHLQSVQKERDEMETRLQSLQFDKEQMASLAEANQTLKLQVEQMQEEAKKAITEQKQKMKRLGSDLTSAQKEMKAKHKAYENAVSILSRRLQESLTAKESAEAELSKLKAQITDGGSNQIAQERIQALETELQAVRSSKLMLEKELQEVISLTSQELEEYREKVLELEDELQESRGFRRKIKRLEEINKKLALELEHERGKLTGLSQSNAALREHNNVLETALAKREADLVQLNLQVQAVLKRKEEEDQQMQQLIQALQASLEKEKSKVKDLKEQVAAAKADAAHNRRHYRAAALELNEVKKELHAKELLVQALQAEVDKLQVEDEKHSQEVSQFQQELAEARSQLQLLQKKLDDKLSEQPLVSQEVEDLKWEVEQKEREIGTLKQQLDMSEQRSHKELEGMQVVLQNIKTELEVVREDLSVTQKDKFMLQAKVSELKNSMKSLLQQNQQLKMDLKHGKMKKRKGENNSSNPVTPVKIPDCPVPAALLEELLKPSTAVSKEPLKNLNSCLRQLKQEMDSLQRQMEEHTITVHESMSSWTQIEEQLMDFTSTSPATASDQQERPALVETKHNCDVSDKEALAL", "length": 1516, "header": "tr|A0A8V0ZGC2-1|A0A8V0ZGC2_CHICK Isoform 1 of Golgin A3 OS=Gallus gallus OX=9031 GN=GOLGA3 PE=1 SV=1 CANONICAL=A0A8V0ZGC2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2/entry#A0A8V0ZAP0-1", "sequence": { "sequence": "MESSSVQQDVLLDNRSSSGAPGTSQEHGDCNANSALPATGDEVNTSSVNLSEVPNEEGSLELNSKADACQNGPELLFPDSPISFDPTSSPQGQESSPGSVESSLPLENEEQIRLQARRRLEEQLRQYRVKRHQERSNQSTSKSRPSSTLDPELMLNPEILPRASTVAMTKEYSFLRTSVPRGPKLGSLGLPASSKERKSSKSSKSSKIRSLADYRTEDSGSGSSAGNLMATDLPGGTLKQSRSGPASVVSEISLPFDTDDRIENSSLAGDSISEIDGSEAGMRLDGNESDSSTYSSVSGKGLCNNLPNSEGKERIPYTINGQKIHPDAIGQFPSISEVLQAAAVEHQAQEQEFNGEIRSRRDSISSSVSMESSVAGTHDEMLQVLKEKMRLEGQLEALSAEANQALKEKAELQAQLAALNMKLQAQVEHSQSSQQKQESLSSEVATLKQSCWDLERAMADLQNTLEAKNASLASSNNDLQLAEEQYQRLMLKVEDMQKSVLTRDSTVHDLRQQLASLQSQLQKVQLERTTLTNKLKASETEITSLQNVRQWYQQQLVLAQEARVRLQSEMANIQAGQMTQAGVLEHLKLENVALSQQLTETQHRSIKEKERIAAQLQNIEADMLDQEAAFMQIQEAKTMVEEDLQRKLEEFEDEKEQLQKMADSAATLEQELDQVKLTLHQRDLQLESLQQEHLDLMKQFTMTQEMLHTKEQTLDDLQTQYDELKARLEEFQSDATSKDDMIQYLQNEKIVLEVALQTAKASQDQLDEGTKRLGEDTEVTSEILEQLRQEMAIRSSQVENLQQENGSLKKQVQKVKEQFLQQKVMVEAYRRDASSKDQLISELKATKKRLDSEMKELKRELLQIQVEKQSLETEHSKLQKEVTEVHQQMVEIENHLQSVQKERDEMETRLQSLQFDKEQMASLAEANQTLKLQVEQMQEEAKKAITEQKQKMKRLGSDLTSAQKEMKAKHKAYENAVSILSRRLQESLTAKESAEAELSKLKAQITDGGSNQIAQERIQALETELQAVRSSKLMLEKELQEVISLTSQELEEYREKVLELEDELQESRGFRRKIKRLEEINKKLALELEHERGKLTGLSQSNAALREHNNVLETALAKREADLVQLNLQVQAVLKRKEEEDQQMQQLIQALQASLEKEKSKVKDLKEQVAAAKADAAHNRRHYRAAALELNEVKKELHAKELLVQALQAEVDKLQVEDEKHSQEVSQFQQELAEARSQLQLLQKKLDDKLSEQPLVSQEVEDLKWEVEQKEREIGTLKQQLDMSEQRSHKELEGMQVVLQNIKTELEVVREDLSVTQKDKFMLQAKVSELKNSMKSLLQQNQQLKMDLKHGKMKKRKGENNSSNPVTPVKIPDCPVPAALLEELLKPSTAVSKEPLKNLNSCLRQLKYDLFLKLY", "length": 1415, "header": "tr|A0A8V0ZAP0-1|A0A8V0ZGC2_CHICK Computationally mapped isoform of Golgin A3 OS=Gallus gallus OX=9031 GN=GOLGA3 PE=1 SV=1 CANONICAL=A0A8V0ZGC2-1" }, "locus": { "chromosome": "15", "start_pos": 1487231, "end_pos": 1468652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051150.1", "url": "https://www.ensembl.org/id/ENSGALT00010051150.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030341.1", "url": "https://www.ensembl.org/id/ENSGALP00010030341.1" } ] } }, { "isoform_ac": "A0A8V0ZGC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2/entry#A0A8V0ZGC2-1", "sequence": { "sequence": "MESSSVQQDVLLDNRSSSGAPGTSQEHGDCNANSALPATGDEVNTSSVNLSEVPNEEGSLELNSKADACQNGPELLFPDSPISFDPTSSPQGQESSPGVPGFHDSLRKSQGTSAEGVALRKEALQSLKLSLPMQETELCSVESSLPLENEEQIRLQARRRLEEQLRQYRVKRHQERSNQSTSKSRPSSTLDPELMLNPEILPRASTVAMTKEYSFLRTSVPRGPKLGSLGLPASSKERKSSKSSKSSKIRSLADYRTEDSGSGSSAGNLMATDLPGGTLKQSRSGPASVVSEISLPFDTDDRIENSSLAGDSISEIDGSEAGMRLDGNESDSSTYSSVSGKGLCNNLPNSEGKERIPYTINGQKIHPDAIGQFPSISEVLQAAAVEHQAQEQEFNGEIRSRRDSISSSVSMESSVAGTHDEMLQVLKEKMRLEGQLEALSAEANQALKEKAELQAQLAALNMKLQAQVEHSQSSQQKQESLSSEVATLKQSCWDLERAMADLQNTLEAKNASLASSNNDLQLAEEQYQRLMLKVEDMQKSVLTRDSTVHDLRQQLASLQSQLQKVQLERTTLTNKLKASETEITSLQNVRQWYQQQLVLAQEARVRLQSEMANIQAGQMTQAGVLEHLKLENVALSQQLTETQHRSIKEKERIAAQLQNIEADMLDQEAAFMQIQEAKTMVEEDLQRKLEEFEDEKEQLQKMADSAATLEQELDQVKLTLHQRDLQLESLQQEHLDLMKQFTMTQEMLHTKEQTLDDLQTQYDELKARLEEFQSDATSKDDMIQYLQNEKIVLEVALQTAKASQDQLDEGTKRLGEDTEVTSEILEQLRQEMAIRSSQVENLQQENGSLKKQVQKVKEQFLQQKVMVEAYRRDASSKDQLISELKATKKRLDSEMKELKRELLQIQVEKQSLETEHSKLQKEVTEVHQQMVEIENHLQSVQKERDEMETRLQSLQFDKEQMASLAEANQTLKLQVEQMQEEAKKAITEQKQKMKRLGSDLTSAQKEMKAKHKAYENAVSILSRRLQESLTAKESAEAELSKLKAQITDGGSNQIAQERIQALETELQAVRSSKLMLEKELQEVISLTSQELEEYREKVLELEDELQESRGFRRKIKRLEEINKKLALELEHERGKLTGLSQSNAALREHNNVLETALAKREADLVQLNLQVQAVLKRKEEEDQQMQQLIQALQASLEKEKSKVKDLKEQVAAAKADAAHNRRHYRAAALELNEVKKELHAKELLVQALQAEVDKLQVEDEKHSQEVSQFQQELAEARSQLQLLQKKLDDKLSEQPLVSQEVEDLKWEVEQKEREIGTLKQQLDMSEQRSHKELEGMQVVLQNIKTELEVVREDLSVTQKDKFMLQAKVSELKNSMKSLLQQNQQLKMDLKHGKMKKRKGENNSSNPVTPVKIPDCPVPAALLEELLKPSTAVSKEPLKNLNSCLRQLKQEMDSLQRQMEEHTITVHESMSSWTQIEEQLMDFTSTSPATASDQQERPALVETKHNCDVSDKEALAL", "length": 1516, "header": "tr|A0A8V0ZGC2-1|A0A8V0ZGC2_CHICK Isoform 1 of Golgin A3 OS=Gallus gallus OX=9031 GN=GOLGA3 PE=1 SV=1 CANONICAL=A0A8V0ZGC2-1" }, "locus": { "chromosome": "15", "start_pos": 1487231, "end_pos": 1467483, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051132.1", "url": "https://www.ensembl.org/id/ENSGALT00010051132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030327.1", "url": "https://www.ensembl.org/id/ENSGALP00010030327.1" } ] } }, { "isoform_ac": "A0A8V0ZGE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2/entry#A0A8V0ZGE2-1", "sequence": { "sequence": "MASSVNLSEVPNEEGSLELNSKADACQNGPELLFPDSPISFDPTSSPQGQESSPGVPGFHDSLRKSQGTSAEGVALRKEALQSLKLSLPMQETELCSVESSLPLENEEQIRLQARRRLEEQLRQYRVKRHQERSNQSTSKSRPSSTLDPELMLNPEILPRASTVAMTKEYSFLRTSVPRGPKLGSLGLPASSKERKSSKSSKSSKIRSLADYRTEDSGSGSSAGNLMATDLPGGTLKQSRSGPASVVSEISLPFDTDDRIENSSLAGDSISEIDGSEAGMRLDGNESDSSTYSSVSGKGLCNNLPNSEGKERIPYTINGQKIHPDAIGQFPSISEVLQAAAVEHQAQEQEFNGEIRSRRDSISSSVSMESSVAGTHDEMLQVLKEKMRLEGQLEALSAEANQALKEKAELQAQLAALNMKLQAQVEHSQSSQQKQESLSSEVATLKQSCWDLERAMADLQNTLEAKNASLASSNNDLQLAEEQYQRLMLKVEDMQKSVLTRDSTVHDLRQQLASLQSQLQKVQLERTTLTNKLKASETEITSLQNVRQWYQQQLVLAQEARVRLQSEMANIQAGQMTQAGVLEHLKLENVALSQQLTETQHRSIKEKERIAAQLQNIEADMLDQEAAFMQIQEAKTMVEEDLQRKLEEFEDEKEQLQKMADSAATLEQELDQVKLTLHQRDLQLESLQQEHLDLMKQFTMTQEMLHTKEQTLDDLQTQYDELKARLEEFQSDATSKDDMIQYLQNEKIVLEVALQTAKASQDQLDEGTKRLGEDTEVTSEILEQLRQEMAIRSSQVENLQQENGSLKKQVQKVKEQFLQQKVMVEAYRRDASSKDQLISELKATKKRLDSEMKELKRELLQIQVEKQSLETEHSKLQKEVTEVHQQMVEIENHLQSVQKERDEMETRLQSLQFDKEQMASLAEANQTLKLQVEQMQEEAKKAITEQKQKMKRLGSDLTSAQKEMKAKHKAYENAVSILSRRLQESLTAKESAEAELSKLKAQITDGGSNQIAQERIQALETELQAVRSSKLMLEKELQEVISLTSQELEEYREKVLELEDELQESRGFRRKIKRLEEINKKLALELEHERGKLTGLSQSNAALREHNNVLETALAKREADLVQLNLQVQAVLKRKEEEDQQMQQLIQALQASLEKEKSKVKDLKEQVAAAKADAAHNRRHYRAAALELNEVKKELHAKELLVQALQAEVDKLQVEDEKHSQEVSQFQQELAEARSQLQLLQKKLDDKLSEQPLVSQEVEDLKWEVEQKEREIGTLKQQLDMSEQRSHKELEGMQVVLQNIKTELEVVREDLSVTQKDKFMLQAKVSELKNSMKSLLQQNQQLKMDLKHGKMKKRKGENNSSNPVTPVKIPDCPVPAALLEELLKPSTAVSKEPLKNLNSCLRQLKQEMDSLQRQMEEHTITVHESMSSWTQIEEQLMDFTSTSPATASDQQERPALVETKHNCDVSDKEALAL", "length": 1473, "header": "tr|A0A8V0ZGE2-1|A0A8V0ZGE2_CHICK Computationally mapped isoform of Golgin A3 OS=Gallus gallus OX=9031 GN=GOLGA3 PE=1 SV=1 CANONICAL=A0A8V0ZGC2-1" }, "locus": { "chromosome": "15", "start_pos": 1508707, "end_pos": 1467483, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051157.1", "url": "https://www.ensembl.org/id/ENSGALT00010051157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030348.1", "url": "https://www.ensembl.org/id/ENSGALP00010030348.1" } ] } }, { "isoform_ac": "A0A8V0ZHI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2/entry#A0A8V0ZHI7-1", "sequence": { "sequence": "MESSSVQQDVLLDNRSSSGAPGTSQEHGDCNANSALPATGDEVNSSVESSLPLENEEQIRLQARRRLEEQLRQYRVKRHQERSNQSTSKSRPSSTLDPELMLNPEILPRASTVAMTKEYSFLRTSVPRGPKLGSLGLPASSKERKSSKSSKSSKIRSLADYRTEDSGSGSSAGNLMATDLPGGTLKQSRSGPASVVSEISLPFDTDDRIENSSLAGDSISEIDGSEAGMRLDGNESDSSTYSSVSGKGLCNNLPNSEGKERIPYTINGQKIHPDAIGQFPSISEVLQAAAVEHQAQEQEFNGEIRSRRDSISSSVSMESSVAGTHDEMLQVLKEKMRLEGQLEALSAEANQALKEKAELQAQLAALNMKLQAQVEHSQSSQQKQESLSSEVATLKQSCWDLERAMADLQNTLEAKNASLASSNNDLQLAEEQYQRLMLKVEDMQKSVLTRDSTVHDLRQQLASLQSQLQKVQLERTTLTNKLKASETEITSLQNVRQWYQQQLVLAQEARVRLQSEMANIQAGQMTQAGVLEHLKLENVALSQQLTETQHRSIKEKERIAAQLQNIEADMLDQEAAFMQIQEAKTMVEEDLQRKLEEFEDEKEQLQKMADSAATLEQELDQVKLTLHQRDLQLESLQQEHLDLMKQFTMTQEMLHTKEQTLDDLQTQYDELKARLEEFQSDATSKDDMIQYLQNEKIVLEVALQTAKASQDQLDEGTKRLGEDTEVTSEILEQLRQEMAIRSSQVENLQQENGSLKKQVQKVKEQFLQQKVMVEAYRRDASSKDQLISELKATKKRLDSEMKELKRELLQIQVEKQSLETEHSKLQKEVTEVHQQMVEIENHLQSVQKERDEMETRLQSLQFDKEQMASLAEANQTLKLQVEQMQEEAKKAITEQKQKMKRLGSDLTSAQKEMKAKHKAYENAVSILSRRLQESLTAKESAEAELSKLKAQITDGGSNQIAQERIQALETELQAVRSSKLMLEKELQEVISLTSQELEEYREKVLELEDELQESRGFRRKIKRLEEINKKLALELEHERGKLTGLSQSNAALREHNNVLETALAKREADLVQLNLQVQAVLKRKEEEDQQMQQLIQALQASLEKEKSKVKDLKEQVAAAKADAAHNRRHYRAAALELNEVKKELHAKELLVQALQAEVDKLQVEDEKHSQEVSQFQQELAEARSQLQLLQKKLDDKLSEQPLVSQEVEDLKWEVEQKEREIGTLKQQLDMSEQRSHKELEGMQVVLQNIKTELEVVREDLSVTQKDKFMLQAKVSELKNSMKSLLQQNQQLKMDLKHGKMKKRKGENNSSNPVTPVKIPDCPVPAALLEELLKPSTAVSKEPLKNLNSCLRQLKQEMDSLQRQMEEHTITVHESMSSWTQIEEQLMDFTSTSPATASDQQERPALVETKHNCDVSDKEALAL", "length": 1422, "header": "tr|A0A8V0ZHI7-1|A0A8V0ZHI7_CHICK Computationally mapped isoform of Golgin A3 OS=Gallus gallus OX=9031 GN=GOLGA3 PE=1 SV=1 CANONICAL=A0A8V0ZGC2-1" }, "locus": { "chromosome": "15", "start_pos": 1487231, "end_pos": 1467483, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051093.1", "url": "https://www.ensembl.org/id/ENSGALT00010051093.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030284.1", "url": "https://www.ensembl.org/id/ENSGALP00010030284.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416791", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416791", "resource": "KEGG Pathway" }, { "id": "R-GGA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GW86-1", "protein_name": "Golgin subfamily A member 3 isoform X1", "gene_name": "Golga3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLFRVFLVWAALTMDGVPVKQDGFWEDKSSNDISSCPEASPETLGSLALPPDQPNEVQSVSIEVNNSIFREGGSPDRSSQEALCQNGQFPDHPLSLDPTASPVGPDASAGVDGFHDNLRKSQGTSAEGSVRKEALQSLRLSLPMQETQLCSTASSLPLEKEEQVRLQARKRLEEQLIQYRVKRHRERSSQPATKMKLFSTLDPELMLNPENLPRASTVAVTKEYSFLRTSVPRGPKVGSLGLLAQSKEKKSSKSSKIRSLADYRTEDSSDSGGLGSTGDAVGGSLKQSRSSTSVVSEVSPSSETDNRVESASLAGDSVSEADGNESDSSSHSSFSTRGACGVLVNVAMPGAAYMVDGQEISVEALGQFPSIKDVLQSAAAQHQDQNQEVNGEVQSRRDSICSSVSMESSLAETQDEMLQVLKEKMRLEGQLEALSLEATQALQEKAELQAQLAALSTRLQAQVEHSHSSQQKQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRNILSKDNTVHDLRQQMAALQSQLHQVQLERTTLTSKLQASQAEITSLQHARQWYQQQLALAQEARVRLQGEVAHIQVGQMTQAGLLEHLKLENVSLSHQLTETQHRSIKEKERIAVQLQSIEADMLDQEAAFLQIKEAKTMVEEDLQRRLEEFEGEREQLQKVADAAASLEQQLEQVKLTLFQRDQQLAALQQEHLDVIKQLTSTQEALQSKGQSLDELHSRYDELQARLEELQREADSREDTIHFLQNEKIVLEVALQSARNDKEELDRGTQHLEEDTEETSGILEQLRQELAVKSNQVEHLQQETASLRKQIQKVKEQFLQQKVMVEAYRRDATSKDQLISELKATKKRLDSEMKELRQELIKVHGEKKTVEVEHSRLQKEMSLVHQQMADLEGHLQSVQKERDEMETHLQSLQFDKEQMVALTEANETLKKQIEELQQEAKKAITEQKQKMKRLGSDLTSAQKEMKTKHKAYENAVSILSRRLQEALATKEATDAELSQLRAQSTGGSSDPVLHEKIRALEVELQNVGQSKILLEKELQEVITMTSQELEESREKVLELEDELQESRGFRRKIKRLEESNKKLALELEHERGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKQLVEALQASLEKEKMKVNSMKEQMAAAKVEAGHNRRHFKAATLELSEVKKELQAKEHLVQTLQAQADELQIQEGKHSQEIAHFQTELAEARTRLQFLQKQLDEQMSQQPTGSQEMENLKWELDQKEREIQSLKQQLDLTEQHGKKELESTQQTLQTIRSELEMVQEDLSETQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKKKEPKGESNSSSPATPIKIPDCPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQMEEHTITVHESLSSWAQAEAAPAEHAHPRGDTKPHSQNSVPREGLGQ", "length": 1501 }, "evidence": [ { "id": "A0A8V0ZGC2", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9SFD3-1", "protein_name": "Golgin A3", "gene_name": "GOLGA3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSAAAMQEGLVEDRSSSGSSAQPEGPPKPPGSLAPLDQWDEAQCASAKVNRTSDEGRQGDTCLNGPTPQFPEPPSPSGPDASPGVAGFHDNLRKSQGTSAEGIVRKEALQSLRLSLPMQETQLCSTEASLPLEKEEQVRLQARKRLEEQLKQYRVKRQQERSSQPVTKTRLFSTLDPELMLNPETLPRASAVAMTKEYSFLRTSVPRGPKVGSLGLLAHPKEKKSSKSSKIRSLADYRTEDSDVRNSGGNVPAPDSTRGSLKQNRGSGTSVVSEVSLCPEADDRLENASLTGDNVSEADGTESDSSSYSSVSARGTPGIPANMGGTREAPYMVSGREIAVGALGQFPSISDVLQAAAAEHQEQRQEVNGETRSRTNSICSSVSLESSVAETHDEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALHTRLQAQLEHSHSSQQRQDSLSSEVDTLKQSCWDLEQAMTDLQNMLEAKNASLASSNSDLQVAEEQYQRLMAKVEEMQRSILSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEIASLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMSQAGLLEHLKLENVSLSHQLTETQQRSIKEKERIAAQLQGIEADMLDQEAAFVQIQEAKTMVEEDLQRRLEEFEDEKEQLQKMVASAAVLEQQLEQVKLTLHQRDQQLEALQQEHLDLLKQFTSTQETLQTREQSLGDLQVRYDELQARLDELQGEAASREDAIQALQNEKIVLEVALQAAHSSREEFDRGAKRLEEGAQDTSDTLEQLRQELAIKSSQVEHLQQEAGALKKQTQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATKKRLDSEVKELRQELMKLQGEKRSVEVEHSRLQKEMSQIQQQVVDLEGHLQSAQRERDEMETQLQSLQFDKEQMVAVTEANEVLKKQIEELQQEATKAITEQKQKMKRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAAEAELSQLRAQAAAGGSDLTLHERVQVLEAELQAVGHSKMMLERELQEVISLTGQELEEQREKVLELEDELQESRGFRRKIKRLEESNKKLALELEHERGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKQLVQALQAALQKEKVMVHSLEEQVAAAKAEAGHNRRHFKAATLELSEVKKELQAKEQEVQRLQAEADGLQIQEGKHSQEIAEFQAELAEARTQLQLLQKQLDEQLSKEPIGNQEMENLKWEVDQKEREIQSLKQQLDLTEHQSKQELDGIQQSLQNIKSELEMVREDLSMTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKTRKEPKGEASSSSPVTPVKIPDCPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQMEAHAVTVHESLSSWTQGDPASPSPPGDHANPRGDTERHGQGRASQEGLGTVTTEHPHPECL", "length": 1496 }, "evidence": [ { "id": "A0A8V0ZGC2", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2CEB4-1", "protein_name": "Golgin subfamily A member 3", "gene_name": "golga3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENGNNGMVSIEAKPPQHPDAQHCKNPNSNTVESLKPERSLVTEKIPNGHVKAELLPNGEAMVEGQDVGGGSTPPSATPSPGSRLSDSSPSTELDPGVVSFPDSLERSEGSVHTGDALQSLRLSIPMQETELSSTDPCVEMENEEKIRQEARRRLEEQLKQYRAQRHTERTRRSTPKSRPFSTLDPELMLHPEGLPRANTVAMTKEYSFLRTSVPRGPKLGSLGIPSSREKKSKSSRSSKIHSLADYKTPESEGSGGAVSASADSSFTSLHSTISSVSTVSEISISSEANNHSESSQLIRDNISEVDGSESGFRADGNDSDSSSYSSVSTTGTYNMLSAIVNRPKAPYTVEGREIAAEAMGHFPSLQEVLQAATEERHMEELEQDREGSVEPRSRRDSFSSSVSYGSSVMGTHDEMLQVLKEKMRLEGQLESLSSEASQALKEKTELQAQLATVNAQLKAQVEQTQAGQERQSTLKTEVTTLRSNCSALEKAMVDLQTNLEGKNASLASLGNDLEVAEEQYQRLMVKVEEMQQSLNAKDNTVSELRQQMGGLQTQLQRVQSERNALQSRLKTSQAEVDSLQQLRLWYQQQLNLAQEARVRLQGEMANMQAGQMTQFGVLENLKIENVTLSHKLTETNHRSIKEKERIAVQLQSIEADMLTQEAAIHQIQEAKTMVEEDLQHKLEEFEEEREHLLKLANTATTLERELEQVKLVLFQKDSQLESLQREHLELMKQLTTTQETLQTKEQALNQLEARYQELQVQLEELQTDASAKEETLQYLQNEKIVLEVALQAARADKSELDEGAEKLGEEVLVASDTLDQLRQEVQVKATQIEALQHENGTLKKQAQKLKEQFMQQKVMVEAYRRDASSKEQLISELKASKKRLVAEVKDLKQELLKTEGEKKSAVQEQARLQKEVERVQQQMNGLEAHLQSVQTERDQLDSQLQSLQFDQNQLAAVTEENENLRKRVEQMQNEARTAISEQKVKMKRLGTDLTSAQKEMKAKHKAYENAVGILSRRLQEALAAKETAEAELDKLKAQVADGGNSQELQAKVKSLQGELQAVSQSKAMLEKELQEVITLTSTELEEYQEKVLELEDEQLQESRNFKKRIRRLEDANKKLALELEHEKGKLSGLGKSHSALREHANILEAALAKREADLVQLNLQVQAVLKRKEEEDQQMRQLVQTLQTALEKEKIKVKDLTEQVAEAKLEAAHNRRHYRAAVLELSEIKKDLQAKEELVKALEKEATTLAAQDEKHSEEVSRFREELADAHTQLQILQKQLDDELNKQPVTNQEVEDLKWEVEQKQREMEAQKQQLEMVEQCHQREMQSQQDMLQTIKVELEMVQEELNGTRKDKFMLQAKVGELRNSMKTVLQQNNQLKQDLKNSRLRKQRMDLKGESTPVTPVKIPDCPVPASLLDELLKPSTSVNKEPLNNLHNCLKQLKQEMDSLQKQMEEHTVTVTSLASPEDELQKLGLHDSSESSNKEDKEEMLPS", "length": 1494 }, "evidence": [ { "id": "A0A8V0ZGC2", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZLD5-1", "protein_name": "Golgin A3", "gene_name": "Golga3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGASAKQDGLWENKSSSDISSCPEASLETVGSLAQLPDQQDTAQDGSVEVNRVFKEEGSPDRSSQVPICQNGQIPDLQLSLDPTTSPVGPDASTGVDGFHDNLRKSQGTSAEGSVRKEALQSLRLSLPMQETQLCSTASSLPLEKEEQVRLQARKRLEEQLMQYRVKRHRERSSQPATKMKLFSTLDPELMLNPENLPRASAVAVTKEYSFLRTSVPRGPKVGSLGLLAHSKEKKNSKSSKIRSLADYRTEDPSDSGGLGSTADAVGSSLKQSRSSTSVVSEVSPSCETDNRAESASLAGDSVSEADGNESDSSSHSSFSARGACAVLGNVGTPGAAYVVDGQEISAEALGQFPSIKDVLQAAAAQHQDQNQEANGEVQSRRDSICSSVSMESSFAEPQEELLQILKDKRRLEGQVEALSLEASQALQEKAELQAQLAALSTRLQAQVEHSHSSQQKQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEAMQRNILSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLQASQAEITSLQQARQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSHQLTETQHRSIKEKERIAVQLQSIEADMLDQEAAFVQIREAKTMVEEDLQRKLEEFEGEREQLQKVADAAASLEQQLEQVKLTLFQRDQQLAALQQEHLDVIKQLTSTQEALQAKGQSLDDLQTRYDELQARLEELQREADSREDAIHFLQNEKIVLEVALHSARSDKEELDRGARRLEEDTEETSGLLEQLRQDVAVKSNQVEHLQQETATLRKQMQKVKEQFLQQKVMVEAYRRDAASKDQLINELKATKKRLDSEMKELRQELIKLHGEKKTVEVEHSRLQKDMSLVHQQMAELEGHLQSVQKERDEMEIHLQSLKFDKEQMIALTEANETLKKQIEELQQEAKKAITEQKQKMKRLGSDLTSAQKEMKTKHKAYENAVSILSRRLQEALANKEATDAELNQLRAQSTGGSSDPALHEKIHALEVELQNVGQSKILLEKELQEVITMTSQELEESREKVLELEDELQESRGFRRKIKRLEESNKKLALELEHERGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKQLVQALQISLEKEKTEVSSLKEQMAAARVEAGHNRRHFKAATLELSEVKKELQAKEHLVQTLQAEVDELQIQEGKHSQEIAQFQTELAEARTQLQLLQKKLEEQRSQQPTGSQEMEDLKWELDQKEREIQSLKQQLDLTEHQGKKELEGTQQTLQTIKSELETVQEDLSETQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKKKEPKGESSSSSPATPIKIPDCPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQMEEHTITVHESLSSWAQVEAAPAEHAHARGDTKVHNQNSVPGEGLGQ", "length": 1487 }, "evidence": [ { "id": "A0A8V0ZGC2", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RI72-1", "protein_name": "Golgin A3", "gene_name": "GOLGA3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"length": 1488 }, "evidence": [ { "id": "A0A8V0ZGC2", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q08378-1", "protein_name": "Golgin subfamily A member 3", "gene_name": "GOLGA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1498 }, "evidence": [ { "id": "A0A8V0ZGC2", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1401, "end_pos": 1403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1402, "end_pos": 1404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 846, "end_pos": 848, "annotation": "n_glycosylation_sequon" }, { "start_pos": 968, "end_pos": 970, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1401, "end_pos": 1403 }, { "start_pos": 1402, "end_pos": 1404 }, { "start_pos": 14, "end_pos": 16 }, { "start_pos": 178, "end_pos": 180 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 846, "end_pos": 848 }, { "start_pos": 968, "end_pos": 970 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZI75-1", "uniprot_ac": "A0A8V0ZI75", "uniprot_id": "A0A8V0ZI75_CHICK", "mass": { "chemical_mass": 82177.0, "monoisotopic_mass": 82177.0 }, "refseq": { "ac": "NP_001292367", "name": "exostosin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292367" }, "gene_names": [ { "name": "EXT2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ] }, { "name": "EXT2", "type": "synonym", "evidence": [ { "id": "NP_001292367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292367" } ] }, { "name": "exostosin-2", "type": "synonym", "evidence": [ { "id": "NP_001292367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292367" } ] } ], "protein_names": [ { "name": "Exostosin-2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.224", "type": "synonym", "evidence": [ { "id": "A0A8V0ZI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75/entry#names_and_taxonomy" } ] }, { "name": "Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75/entry#names_and_taxonomy" } ] }, { "name": "exostoses (multiple) 2", "type": "synonym", "evidence": [ { "id": "NP_001292367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292367" } ] }, { "name": "exostosin 2", "type": "synonym", "evidence": [ { "id": "NP_001292367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292367" } ] }, { "name": "exostosin-2", "type": "synonym", "evidence": [ { "id": "NP_001292367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292367" } ] } ], "function": [ { "annotation": "Glycosyltransferase forming with EXT1 the heterodimeric heparan sulfate polymerase which catalyzes the elongation of the heparan sulfate glycan backbone. Glycan backbone extension consists in the alternating transfer of (1->4)-beta-D-GlcA and (1->4)-alpha-D-GlcNAc residues from their respective UDP-sugar donors. Both EXT1 and EXT2 are required for the full activity of the polymerase since EXT1 bears the N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity within the complex while EXT2 carries the glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Heparan sulfate proteoglycans are ubiquitous components of the extracellular matrix and play an important role in tissue homeostasis and signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZBJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBJ8#function" }, { "database": "UniProtKB", "id": "ARBA00053270", "url": "https://www.uniprot.org/uniprotkb/ARBA00053270#function" }, { "database": "UniProtKB", "id": "A0A8V0ZC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC80#function" }, { "database": "UniProtKB", "id": "A0A8V0ZC90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC90#function" }, { "database": "UniProtKB", "id": "A0A8V0ZI66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI66#function" }, { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75", "locus": { "chromosome": "5", "start_pos": 21338356, "end_pos": 21259957, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019800", "url": "https://www.ensembl.org/id/ENSGALG00010019800" } ] } } ], "crossref": [ { "id": "A0A8V0ZI75", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZI75", "database": "AlphaFoldDB", "categories": [] }, { "id": "425859", "url": "https://www.ncbi.nlm.nih.gov/gene/425859", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425859", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425859", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NCTFWDC", "url": "https://omabrowser.org/oma/group/NCTFWDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAP1", "url": "https://www.orthodb.org/?gene=A0A8V0ZAP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBJ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZBJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC61", "url": "https://www.orthodb.org/?gene=A0A8V0ZC61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC80", "url": "https://www.orthodb.org/?gene=A0A8V0ZC80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC90", "url": "https://www.orthodb.org/?gene=A0A8V0ZC90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI66", "url": "https://www.orthodb.org/?gene=A0A8V0ZI66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI75", "url": "https://www.orthodb.org/?gene=A0A8V0ZI75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48261:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48261:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001292367", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292367", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16213", "url": "https://www.rhea-db.org/rhea/16213", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCASAKYNTRGPALIPRMKTKHRIYYITLFSIVLLGLIATGVFQFWPHSIESSSDWTVEKRSVHDVPVVKLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYSLKKYVDEYGTSVSNTISREYNELLTAISDSEYYTDDVNRACLFVPSIDVLNQNTLRIKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPERGPGPRRYFILSSQMSLHPEYQSELEALQAENGESVLLLDKCTNLSDGVPAVRKRCHNSQMFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVIIADSYILPFSEVLDWKRASVVIPEDKMPEMYSILQSVPQRQIEEMQRQARWFWEAYFRSMKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWSSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKSVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "length": 718, "header": "tr|A0A8V0ZI75-1|A0A8V0ZI75_CHICK Isoform 1 of Exostosin-2 OS=Gallus gallus OX=9031 GN=EXT2 PE=3 SV=1 CANONICAL=A0A8V0ZI75-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75/entry#A0A8V0ZAP1-1", "sequence": { "sequence": "MCASAKYNTRGPALIPRMKTKHRIYYITLFSIVLLGLIATGVFQFWPHSIESSSDWTVEKRSVHDVPVVKLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYSLKKYVDEYGTSVSNTISREYNELLTAISDSEYYTDDVNRACLFVPSIDVLNQNTLRIKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPERGPGPRRYFILSSQMSLHPEYQSELEALQAENGESVLLLDKCTNLSDGVPAVRKRCHNSQMFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVIIADSYILPFSEVLDWKRASVVIPEDKMPEMYSILQSVPQRQIEEMQRQARWFWEAYFRSMKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWSSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDPCRAFHLALQPLSPSVCLLVILIHGLQSFCCL", "length": 531, "header": "tr|A0A8V0ZAP1-1|A0A8V0ZI75_CHICK Computationally mapped isoform of Exostosin-2 OS=Gallus gallus OX=9031 GN=EXT2 PE=3 SV=1 CANONICAL=A0A8V0ZI75-1" }, "locus": { "chromosome": "5", "start_pos": 21307393, "end_pos": 21263703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047817.1", "url": "https://www.ensembl.org/id/ENSGALT00010047817.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028266.1", "url": "https://www.ensembl.org/id/ENSGALP00010028266.1" } ] } }, { "isoform_ac": "A0A8V0ZBJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75/entry#A0A8V0ZBJ8-1", "sequence": { "sequence": "MHGEMAKHSATNPQVTSGGSDKREEIIDSIMCASAKYNTRGPALIPRMKTKHRIYYITLFSIVLLGLIATGVFQFWPHSIESSSDWTVEKRSVHDVPVVKLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYSLKKYVDEYGTSVSNTISREYNELLTAISDSEYYTDDVNRACLFVPSIDVLNQNTLRIKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPERGPGPRRYFILSSQMSLHPEYQSELEALQAENGESVLLLDKCTNLSDGVPAVRKRCHNSQMFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVIIADSYILPFSEVLDWKRASVVIPEDKMPEMYSILQSVPQRQIEEMQRQARWFWEAYFRSMKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWSSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKSVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "length": 748, "header": "tr|A0A8V0ZBJ8-1|A0A8V0ZI75_CHICK Computationally mapped isoform of Exostosin-2 OS=Gallus gallus OX=9031 GN=EXT2 PE=3 SV=1 CANONICAL=A0A8V0ZI75-1" }, "locus": { "chromosome": "5", "start_pos": 21333116, "end_pos": 21261125, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047887.1", "url": "https://www.ensembl.org/id/ENSGALT00010047887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028298.1", "url": "https://www.ensembl.org/id/ENSGALP00010028298.1" } ] } }, { "isoform_ac": "A0A8V0ZC61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75/entry#A0A8V0ZC61-1", "sequence": { "sequence": "MCASAKYNTRGPALIPRMKTKHRIYYITLFSIVLLGLIATGVFQFWPHSIESSSDWTVEKRSVHDVPVVKLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYSLKKYVDEYGTSVSNTISREYNELLTAISDSEYYTDDVNRACLFVPSIDVLNQNTLRIKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPERGPGPRRYFILSSQMSLHPEYQSELEALQAENGESVLLLDKCTNLSDGVPAVRKRCHNSQMFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVIIADSYILPFSEVLDWKRASVVIPEDKMPEMYSILQSVPQRQIEEMQRQARWFWEAYFRSMKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWSSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEALETEVTEVTSSPSLNLRARKGFRKVL", "length": 525, "header": "tr|A0A8V0ZC61-1|A0A8V0ZI75_CHICK Computationally mapped isoform of Exostosin-2 OS=Gallus gallus OX=9031 GN=EXT2 PE=3 SV=1 CANONICAL=A0A8V0ZI75-1" }, "locus": { "chromosome": "5", "start_pos": 21309233, "end_pos": 21263703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047823.1", "url": "https://www.ensembl.org/id/ENSGALT00010047823.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028272.1", "url": "https://www.ensembl.org/id/ENSGALP00010028272.1" } ] } }, { "isoform_ac": "A0A8V0ZC80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75/entry#A0A8V0ZC80-1", "sequence": { "sequence": "MRALRRGWNNGMSGQKHTASFMREEIIDSIMCASAKYNTRGPALIPRMKTKHRIYYITLFSIVLLGLIATGVFQFWPHSIESSSDWTVEKRSVHDVPVVKLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYSLKKYVDEYGTSVSNTISREYNELLTAISDSEYYTDDVNRACLFVPSIDVLNQNTLRIKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPERGPGPRRYFILSSQMSLHPEYQSELEALQAENGESVLLLDKCTNLSDGVPAVRKRCHNSQMFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVIIADSYILPFSEVLDWKRASVVIPEDKMPEMYSILQSVPQRQIEEMQRQARWFWEAYFRSMKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWSSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKSVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "length": 748, "header": "tr|A0A8V0ZC80-1|A0A8V0ZI75_CHICK Computationally mapped isoform of Exostosin-2 OS=Gallus gallus OX=9031 GN=EXT2 PE=3 SV=1 CANONICAL=A0A8V0ZI75-1" }, "locus": { "chromosome": "5", "start_pos": 21333116, "end_pos": 21262531, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047870.1", "url": "https://www.ensembl.org/id/ENSGALT00010047870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028292.1", "url": "https://www.ensembl.org/id/ENSGALP00010028292.1" } ] } }, { "isoform_ac": "A0A8V0ZC90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75/entry#A0A8V0ZC90-1", "sequence": { "sequence": "MCASAKYNTRGPALIPRMKTKHRIYYITLFSIVLLGLIATGVFQFWPHSIESSSDWTVEKRSVHDVPVVKLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYSLKKYVDEYGTSVSNTISREYNELLTAISDSEYYTDDVNRACLFVPSIDVLNQNTLRIKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPERGPGPRRYFILSSQMSLHPEYQSELEALQAENGESVLLLDKCTNLSDGVPAVRKRCHNSQMFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVIIADSYILPFSEVLDWKRASVVIPEDKMPEMYSILQSVPQRQIEEMQRQARWFWEAYFRSMKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWSSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKSVIKVTPRKKFKCPECTAIDGLSLDQTHMVESLNISW", "length": 678, "header": "tr|A0A8V0ZC90-1|A0A8V0ZI75_CHICK Computationally mapped isoform of Exostosin-2 OS=Gallus gallus OX=9031 GN=EXT2 PE=3 SV=1 CANONICAL=A0A8V0ZI75-1" }, "locus": { "chromosome": "5", "start_pos": 21338282, "end_pos": 21263703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047896.1", "url": "https://www.ensembl.org/id/ENSGALT00010047896.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028302.1", "url": "https://www.ensembl.org/id/ENSGALP00010028302.1" } ] } }, { "isoform_ac": "A0A8V0ZI66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75/entry#A0A8V0ZI66-1", "sequence": { "sequence": "MCASAKYNTRGPALIPRMKTKHRIYYITLFSIVLLGLIATGVFQFWPHSIESSSDWTVEKRSVHDVPVVKLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYSLKKYVDEYGTSVSNTISREYNELLTAISDSEYYTDDVNRACLFVPSIDVLNQNTLRIKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPERGPGPRRYFILSSQMSLHPEYQSELEALQAENGESVLLLDKCTNLSDGVPAVRKRCHNSQMFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVIIADSYILPFSEVLDWKRASVVIPEDKMPEMYSILQSVPQRQIEEMQRQARWFWEAYFRSMKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWSSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKSVIKVTPRKKFKCPECTAIDGLSLDQTHMVERELL", "length": 676, "header": "tr|A0A8V0ZI66-1|A0A8V0ZI66_CHICK Computationally mapped isoform of Exostosin-2 OS=Gallus gallus OX=9031 GN=EXT2 PE=3 SV=1 CANONICAL=A0A8V0ZI75-1" }, "locus": { "chromosome": "5", "start_pos": 21328683, "end_pos": 21263703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047840.1", "url": "https://www.ensembl.org/id/ENSGALT00010047840.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028285.1", "url": "https://www.ensembl.org/id/ENSGALP00010028285.1" } ] } }, { "isoform_ac": "A0A8V0ZI75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75/entry#A0A8V0ZI75-1", "sequence": { "sequence": "MCASAKYNTRGPALIPRMKTKHRIYYITLFSIVLLGLIATGVFQFWPHSIESSSDWTVEKRSVHDVPVVKLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYSLKKYVDEYGTSVSNTISREYNELLTAISDSEYYTDDVNRACLFVPSIDVLNQNTLRIKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPERGPGPRRYFILSSQMSLHPEYQSELEALQAENGESVLLLDKCTNLSDGVPAVRKRCHNSQMFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVIIADSYILPFSEVLDWKRASVVIPEDKMPEMYSILQSVPQRQIEEMQRQARWFWEAYFRSMKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWSSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKSVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "length": 718, "header": "tr|A0A8V0ZI75-1|A0A8V0ZI75_CHICK Isoform 1 of Exostosin-2 OS=Gallus gallus OX=9031 GN=EXT2 PE=3 SV=1 CANONICAL=A0A8V0ZI75-1" }, "locus": { "chromosome": "5", "start_pos": 21333116, "end_pos": 21263703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047878.1", "url": "https://www.ensembl.org/id/ENSGALT00010047878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028295.1", "url": "https://www.ensembl.org/id/ENSGALP00010028295.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:425859", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425859", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KAH7-1", "protein_name": "Exostosin-2", "gene_name": "Ext2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSARRVRRGELEAGAAFPGWLWLTWCWRRPPVTARSDTAVARAPRPKPVAERGAEREAAGSEVCEDEDICVIMCASVKSNIRGPALIPRMKTKHRIYYVTLFSIVLLGLIATGMFQFWPHSIESSSDGGVEKRSIREVPVVRLTADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVDDAGVPVSSAISREYNELLTAISDSDYYTDDISRACLFVPSIDVLNQNPLRIKETAQALAQLPRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVFSPLSAEVALPEKAPGSRRYFLLSSQMAIHPEYREELEALQAKHRESVLVLDKCTNLSEGVLSIRKRCHQHQVFDYPQVLQEATFCTVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVIPEEKMSDVYSILQNIPQRQIEEMQRQARWFWEAYFRSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWASVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEESLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "length": 791 }, "evidence": [ { "id": "A0A8V0ZI75", "url": "https://omabrowser.org/oma/group/A0A8V0ZI75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3S5ZPA0-1", "protein_name": "Exostosin-2", "gene_name": "EXT2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGALGVRPPSPVACPGLPPLVPALPAQRWRPGAPRHPTRAAVARAPRHEPVTKRGAQPEAAVAEECEEEAVGVIMCASVKYNIRGPALIPRMKTKHRIYYITLFSIVLLGLIATGMFQFWPHSIESSGDWSVEKRSVRDVPLVRLPADSPVPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVGEAGVPVSSTISREYNELLTAISDSDYYTDDVTRACLFVPSIDLLNQNSLRVKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRRYFLLSSQVALHPEYREDLAALQARHGEAVLVLDKCSNLSEGVPAARRRCHQQQAFDYPQVLQEATFCMVLRGARLGQAVLSDVLRAGCVPVIIADSYVLPFSEVLDWKRASVVVPEEKMSDVYSILQSIPRRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEDWNDPPAVKWGSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "length": 793 }, "evidence": [ { "id": "A0A8V0ZI75", "url": "https://omabrowser.org/oma/group/A0A8V0ZI75/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A9J7H1L8-1", "protein_name": "Exostosin-2", "gene_name": "Ext2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCASVKYNIRGPALIPRMKTKHRFYYVTLFSIVLLGLIATGVFQFWPHSIESSGDGGVEKRSIKEVPVVRLPAASPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVDDAGVPVSSTISREYNELLAAISDSDYYTDDISRACLFVPSIDVLNQSPLRIKETAQALAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVFSPLSTEVALPEKAPGPRRYFLLSSQMAIHPEYREDLEALQAKHRESVLVLDKCTNLSEGVLSVRKRCHQHQVFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDMYSILQNIPQRQIEEMQRQLSLSETLLFPQICFSSNLQEKRTFDVATGIIFGIARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPTVKWTSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEESLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "length": 752 }, "evidence": [ { "id": "A0A8V0ZI75", "url": "https://omabrowser.org/oma/group/A0A8V0ZI75/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P70428-1", "protein_name": "Exostosin-2", "gene_name": "Ext2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCASVKSNIRGPALIPRMKTKHRIYYVTLFSIVLLGLIATGMFQFWPHSIESSSDGGVEKRSIREVPVVRLPTDSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVDDAGVPVSSAISREYNELLTAISDSDYYTDDINRACLFVPSIDVLNQNPLRIKETAQALAQLSRWDRGTNHLLFNMLPGAPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVFSPLSAEMALPEKAPGPRRYFLLSSQMAIHPEYREELEALQAKHQESVLVLDKCTNLSEGVLSVRKRCHQHQVFDYPQVLQEATFCTVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQNIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWASVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEESLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDTHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "length": 718 }, "evidence": [ { "id": "A0A8V0ZI75", "url": "https://omabrowser.org/oma/group/A0A8V0ZI75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q93063-1", "protein_name": "Exostosin-2", "gene_name": "EXT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCASVKYNIRGPALIPRMKTKHRIYYITLFSIVLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACLFVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEALQVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL", "length": 718 }, "evidence": [ { "id": "A0A8V0ZI75", "url": "https://omabrowser.org/oma/group/A0A8V0ZI75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Y169-1", "protein_name": "Exostosin-2", "gene_name": "sotv", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTKIKNLLSFVTQSRAISHTNPREHILNCLTYGLLVIVALCAGFLLWDLSSSPRDGFFHGKRDSHTLILDLEHIQELAVNPEAEQRARNVNCTFWDCLNIYKCEHDRLKVYIYPLQEFVDEQSDKTATTLSSEYFQILEAVLKSRYYTSNPNEACLFLPSLDLLNQNVFDKHLAGAALASLDFWDRGANHIIFNMLPGGAPSYNTVLDVNTDNAIIFGGGFDSWSYRPGFDVAIPVWSPRLVRQHAHATAQRKFLLVVAQLNILPRFVRTLRELSLAHSEQLLLLGACENLDLTMRCPLSQHHKSLEYPRLLSRGKFCLLGRSLRMGQPDLVEIMSQHCIPVIAVDNYVLPFEDVIDWSLASVRIRENELHSVMQKLKAISSVKIVEMQKQVQWLFSKYFKDLKTVTLTALEVLESRIFPLRARSSRQWNTIDTNARSTFNPLFLPSLAPKSQGFTAVILTYDRVESLFLLIQKLAVVPSLQSILVIWNNQKKSPPHLSTFPSISKPLKIRQTKENKLSNRFYPYPEIETEAILTIDDDIIMLTTDELDFGYEVWREFPDHIVGFPSRIHVWENVTMRWHYESEWTNQISMVLTGAAFHHKYWSHMYTHAMPGDIKDWVDEHMNCEDIAMNFLVANITNNPPIKVTPRKKFKCPECTNTEMLSADLNHMRERSACIDRFSKIYGRMPLRTVEFRADPVLFRDNFPDKLKRYNDIGSL", "length": 717 }, "evidence": [ { "id": "A0A8V0ZI75", "url": "https://omabrowser.org/oma/group/A0A8V0ZI75/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "UDP-N-acetylglucosamine transferase complex", "id": "GO:0043541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043541", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "id": "GO:0050508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity", "id": "GO:0050509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "glucuronosyltransferase activity", "id": "GO:0015020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "polysaccharide biosynthetic process", "id": "GO:0000271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" }, { "name": "glycosaminoglycan biosynthetic process", "id": "GO:0006024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16213", "name": "", "equation": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YKR6-1", "A0A8V0ZI75-1" ], "evidence": [ { "id": "16213", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16213" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YKR6", "gene_name": "EXTL1", "activity": [ { "ec_number": "2.4.1.224", "activity": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ] }, { "ec_number": "2.4.1.224", "activity": "", "evidence": [ { "id": "A0A8V0YKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKR6" } ] } ] }, { "uniprot_ac": "A0A8V0ZI75", "gene_name": "EXT2", "activity": [ { "ec_number": "2.4.1.224", "activity": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "A0A8V0ZI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ] }, { "ec_number": "2.4.1.224", "activity": "", "evidence": [ { "id": "A0A8V0ZI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" }, { "id": "PF03016", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exostosin GT47", "eco_id": "ECO_0000259", "start_pos": 101, "end_pos": 380, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZI75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI75" }, { "id": "PF09258", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09258" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl transferase 64", "eco_id": "ECO_0000259", "start_pos": 456, "end_pos": 701, "start_aa": "Phe", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.1.224", "ec_name": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "2.4.1.224", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.1.224" }, { "id": "2.4.1.224", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.1.224" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 288, "end_pos": 290 }, { "start_pos": 637, "end_pos": 639 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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604484.0, "monoisotopic_mass": 604484.0 }, "refseq": { "ac": "XP_015146072", "name": "hemicentin-1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146072" }, "gene_names": [ { "name": "HMCN1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ] }, { "name": "HMCN1", "type": "synonym", "evidence": [ { "id": "XP_015146072", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146072" } ] } ], "protein_names": [ { "name": "Hemicentin-1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2/entry#names_and_taxonomy" } ] }, { "name": "Fibulin-6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2/entry#names_and_taxonomy" } ] }, { "name": "hemicentin-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015146072", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146072" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015146072.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146072", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146072" } ] }, { "annotation": "Involved in transforming growth factor beta-mediated rearrangement of the podocyte cytoskeleton which includes reduction of F-actin fibers and broadening, flattening and elongation of podocytes. Plays a role in basement membrane organization. May promote cleavage furrow maturation during cytokinesis in preimplantation embryos. May play a role in the architecture of adhesive and flexible epithelial cell junctions. May play a role during myocardial remodeling by imparting an effect on cardiac fibroblast migration.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZAP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP5#function" }, { "database": "UniProtKB", "id": "ARBA00053381", "url": "https://www.uniprot.org/uniprotkb/ARBA00053381#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHN4#function" }, { "database": "UniProtKB", "id": "A0A8V0ZNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "common_name": "Chicken", 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"categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146072", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146072", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALGKAQGAGPGAVLLLLLALSSCAAPESGAEAIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLYNFALVPFHDPGIGPVTITTDPKKFQFELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRDHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLTMAVNTWKIPFDPSLKEVTVSLSGPSPAIEIHDPLGKQISKGLGLNELLNIHNSAKVVNVKDPDPGTWTIKTSSSGRHSVRITGLSTIEFRAGFSKKSTLDFKKTSSRPVQGIPTFVLLNTTGILLPARVDHLELLSISGEPLKTLPVKYYPDRKPYGLWNISDFIPPDEAFFLKIMGYDKDGYIFQRVSSVSFSSITPDAPKVTMPNKTPGYYSQPGSVPCHVESLIPFTQHFTKNGVKLGVDQLFKESSSMSWDINRVSLSDEGFYECIANSTAGTGHAQTFLDVSEPPPVIQVPNNVTAVLREGAILTCLVVSTMRYNLTWQRNGRDVRLQEPLRMRVMSNLSLEVKAVQFTDAGKYNCVASNKDGSTTASVFLTVQEPPRIVISPKDQTFVEGSEVSIRCSATGYPKPTVVWTHNEMFIIGSNRYRLTPEGTLIIRQAIPKDAGVYGCLASNSAGTEKQTSILTYIEGPTVTIFQSEILVALGDTTVMECKTTGIPHPQVKWFKGDLELRASAFLIIDTHRGLLKIQETQELDAGDYTCVATNDAGRASGKITLDVGSPPVFIQEPSDESVDIGSNITLPCYVQGYPEPKVKWRRLNGASLFSRPLAVSFISQLRTGALSINNLWVNDEGSYVCEAENQFGRIQSQPATITVTGLVAPLIGISPATANVIEGQQLTLPCVLLAGNPIPDRKWIKNSMVLVSNPYINVRSDGSLHLERVRLQDGGDYTCMASNVAGTNNKTTTVNVYVLPIVQHGQQIFSTIEGIPVTLPCKASGVPKPSITWSKKGEVIFPSNEKFSAGSDGSLYVVSPEGEETGEYVCTATNAAGYATRKVQLTVYVKPRVSRPGDQQGHGPVEISVITGDDVTLPCEVKSLPPPIITWAKETQLISPFSLRHTFLLSGSMKISETQVSDSGMYFCVATNIAGNVTQSVKLSVHVPPKIQRGPQIMKVQAGHRVDIPCSAQGNPPPAITWFRGSSAVPIGSGQPTHSLGGALSISNVQLSNAGIYRCIASNAAGSDTSEITIQVQEPPTMDDLDPQYNNPFQERVVNQRIAFPCPVKGTPKPVIKWLHNGRELTGREPGISILENDMLLIIASITPSDNGEYICVATNEAGRTERKYNLEVHVPPEIRDQERVTNTSVVVNHPISLFCEVFGNPFPVISWYKEDIQVVESNTLHQILHNGKILKLLKATVDDAGQYSCKAINVAGSSEKLFNLYILVPPSIIGADTPSEIAVILNQETSLECRAKGFPFPGIHWFKDSMPLFLGDPNVELLEKGQVLHIKSARMVDKGHYQCSATNAAGKQIKEVKLIIHVPPSIKGGNITTEVSALLNNLINLDCETKGIPVPTITWYKEGRRIISSPQALYVDRGQFLQIPHAQVSDSAKYTCHVTNAAGAAEKTYEVDVYVPPVIEGDAETAQSRQVVAGNSLTLECKAAGNPSPLLTWLKDGVPVKASDNLRVVSGGKKLEILNAVEADRGQYLCVATSIAGEQEIKYGVEILVPPFVEGGDEFLDYIVVLHSPLELDCSATGTPLPTITWLKGGQPIEEGTGHKILLSGQKFLISRAQVSDTGHYKCVAVNVAGEHEREFVVTVHVPPTIKSAGTSERAVVVHKAVTLQCIANGIPSPSITWLKDGQPVNTARGNTRLESSGRVLQVAEALLEDAGRYTCVAINAAGEAQQHIRLRVHEPPSLEDAGKMLNETVVVNNPIHLECRALGNPLPAITWYKDSHSLTSAASVTFLNKGQVLEIEGAQISDTGIYKCVAVNIAGTAELSYSLQVHVPPSISDSSDTVTAVVNNLVRMECEARGIPAPILTWLKDGSPVSSFSDGLQILSGGRVLVLTSAQISDTGKYTCVAVNAAGESQRDIDLRVYVPPNIMGEEQNVSVLISQAAELLCQSNAVPLPMLMWLKDGRPLLNKPGLSISEDGSVLKIEGAQVQDTGRYTCEATNVAGKTKKNYNVNIWVPPSIYGSDDTSQLTVIEGSLISLICESTGIPPPSLTWKKSGSPLVADQSGRVRILSGGRQLQISVAEMSDAASYICIASNVAGSAKKEYSLQVYTRPVILDSGSYPSEVVAAQGSEISLECKAQGIPEPAVTWMKDGRPLVSGRDVAVLHDGHFLLLRNIQVSDTGHYVCVAANVAGLYDRKYDLNVHVPPDIAGDLQLPENISTVEKNPISLVCEASGIPLPSVMWLKNGWPVTSNTSVQILSGGRTLRLTHTTVSDEGHYTCVVTNAAGEARKDFYLSVLVPPGIVDENKQEDMKVKEKNSVTLTCEVIGNPVPQITWIKDGQPLMEDKDHRFLSSGRFLQITNAQVSDTGRYTCVASNTAGDKSKSYFLNVLVSPTIVGADSHGSAEEVTVILNSPTSLVCEAYSYPPATITWLKDGSLLESNRNIHILPGGRILQILSAQKHSAARYTCIATNEAGETMKHYEVQVYIPPTINRGDVPGMDLSPKEMKIKINHSLTLECEAHAVPAAAISWYKDGQPLKPDDRVIIQASGHTLQITEAQVSDTGRYTCLASNIAGEDEVEFDINIQVPPSFQKPYRGWESGNMVDTGRGGENKDVIINNPLSLYCETDAVPPPVLTWYKDGYPLNSSDKVLILPGGRVFQIPRARAEDAGRYMCAAVNEAGEDSIHYNVHVLLPPSIRGADGDLPEEVNVLGNKVAVMDCVTSGSPSPSITWEKDGHLLAEDNKHSFLSNGRRLQILNSQVTDTGRYVCVVENIAGRAKKYFNLNVHVPPSVVGANPENLTVVVNNLISLTCEVTGFPPPDLSWLKNGKPVSLNTNTFIVPGARTLQIPQAKLSDDGEYTCIARNHAGESQKKSFLTVLVPPGIKDHSGTSVTVFNVRVGTPVMLECKASAIPPPVITWYKNRRMISESANVEILADGQTLQIKGAEVSDTGQYVCKAINIAGRDDKNFHLNVYVPPNIEGPEEELVIETISNPVAFICDATGIPPPTLVWLKNGKPLENSNSLDVHIFSGGSRLQIAHSQLLDSGTYTCIASNVEGKAQKRFVLSVQVPPSIVGSEMPREVGVLLGEGIQLVCNATGVPMPVVQWLKDGKTVASDNLERIRVAPDGSTLNIFRALTSDTGKYTCVATNPAGEEDQIFNLSVYVPPTITNNKSEPEDLAALLESSINIGCAATGMPSPQINWLKNGLPLSVSSRIRLLSAGQILRLVRVQISDAGVYTCVASSRAGVDNKHYNLQIFVPPSLDNARGTEEVTVAKGSSASLKCFTDGAPPPAMSWFKNGHPLSLGAHQNLNNQGMVLHFVEAEIGDVGKYTCVAANKAGDVSKHFSLKVLEPPQINGSGQPEELSVIVNNPLELLCISTGIPIPKISWMKDGRPLLQNDNIHVIREGLRITSAQVKDAGRYTCLAFSPAGDDDKEYLVRVHVPPNIAGTSGVQDLTVLQNRQIILECKSDAVPPPIISWLKNGELLEGTPRIRILSNGRYMQINNADLGDTANYTCVASNIAGKMTREFMLAVHVAPTIRSSPQTTVVHLNSSVVLECTAEGVPTPRIAWRKDGNVFNGNNTRYSILEDGSLQIHSAHVTDTGRYLCMATNAAGTERKQIDLQVLVPPTIASGHTNITVTVNVQTTLPCEATGIPRPAVSWKKNGHLLSLDQNQNTYRLLSSGSLVIISPTVDDTAVYECSVSNDAGEDQRAVELTVQVPPSIADEATDLLVTKLSPVVISCTASGVPVPSVHWTKNGVKLLPRGDGYRILPSGAVEIPAVQLAHAGQYTCVARNAAGSAHRHTTLHVQERPVIQIQPGMLDVIVNNSILLPCEAVGTPRPIITWQKEGINIMTTGNSYMALPNGSLWITESTVEDAGTYTCVAQNLAGTALGKIKLKVQVPPVIKSHLKEYVVPVDQSVTLQCEAEGNPGPEISWHKDGQQVAESMRRRILSTGALQIVFVQPGDTGHYTCIAANVAGSSSSSMELVVQTPPKIHNTEAHYTVTEDSRAVLACMADGIPTPIINWKKDNTLLTETVGKYKTVPGGDLILDNVVPEDSGTYTCTAMNAAGEDTHAVTLVVHVLPAFTELPGDVTLTKGEQLRLACRASGIPVPKITWTFNNNVIPAQHDDVSGHSELVIERVSKDDSGTYACTAENAVGSIRAIGFVYVKEPPVFRGNYHPSRIEPLGGNAMLNCEVRGDPPPTIQWSKEGVGVQTSKRIQQLNNGSLAIYGTVNEDAGDYKCVATNDAGVVERSLTLTLQSPPVITIEPAGTTVEAGATVMLNCQASGEPPPAIRWSRQGHPFVSDDRMTVLSNGSLHIIAAQKEDTSEYECVARNQMGSVLVRVPLTVQVRGGFSDWLEWQPCSVTCGQGVQKRARWCNNPLPANGGRPCEGPDTDVRSCHNKPCPVDGEWSSWLPWGPCSESCGKGTQTRLRLCSSPSPSHGGSHCRGPDVQRQVCSKRRCPVDGKWAPWGSWSACTVSCGGGSSQRTRQCSDPAPQFGGHRCEGNNIQVDFCNSDPCPIHGSWGPWGSWGTCSRSCNGGQVRRYRGCDSPRPSSGGRACAGADMQIQRCGTGLCPVNGNWGPWQTWSQCSASCGGGEQTRTRLCSNPAPLYNGHPCPGDSSQISRCNSQACPGGPSRALGSIIGNINDIEFGIASLNATVTDSPNSESRVIHAKITSIPRSLGPALRKLVSILSPVYWTTAKEVGEAMNGFTLTDAIFKRETQVEFATGEVLRMTHIARGLDSDGALLLDVVVNGHVLQLQPLANVNMKDYTEDYIQTGPGQLYAYSTRLFAVDGVSVPYMWNHTITYDHTKGKMPFLVETLHASSITTEYNPLEETLAFKIHASISKGDHNNQCPAGFELNSSGPYCTDEDECAVRNPCSHTCHNAVGTYHCSCPKGLTIAADGRMCQDVDECVLGRHACHTDQDCENSAGSYHCVLRCRTGFRRAVDGLSCQDINECQESNSCHQHCINTVGSFHCGCDPGYQLKGRKCIDVNECRQNVCRPDQLCKNTRGGYKCIELCPNGMTKAENGTCIDINECHDRTHQCHYNQICENMQGSYRCVCPRGYRSQGLGRPCVDINECEQVPKPCAFQCTNTPGSFKCICPPGQHLLGDGKSCAGLERLLHSGAYYNIYNYAQFSPIRDNYQPQRSYRHSSNLYSSFSEYRNSRIPVSRTKRSIRETCPEGYEARNDRCVDIDECEARDTCQHECRNTLGSYQCACPSGYHLMPNGKTCQDIDECLKQDTGCGASQMCFNMRGSYQCIETSCPPNYQREPHSGFCLKNCPANDLECALSTYALEYKFVSLPFGIAAGQDLIRLVAYTQDQVMHPRTTFLMADEEPTVPFALRDENLKGVVFTTRPLQEPKTYHMRVRALSYSVDGNIEYQTTFIVYIAVSAYPY", "length": 5579, "header": "tr|A0A8V0ZHJ2-1|A0A8V0ZHJ2_CHICK Isoform 1 of Hemicentin-1 OS=Gallus gallus OX=9031 GN=HMCN1 PE=4 SV=1 CANONICAL=A0A8V0ZHJ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2/entry#A0A8V0ZAP5-1", "sequence": { "sequence": "MALGKAQGAGPGAVLLLLLALSSCAAPESGAEAIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLYNFALVPFHDPGIGPVTITTDPKKFQFELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRDHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLTMAVNTWKIPFDPSLKEVTVSLSGPSPAIEIHDPLGKQISKGLGLNELLNIHNSAKVVNVKDPDPGTWTIKTSSSGRHSVRITGLSTIEFRAGFSKKSTLDFKKTSSRPVQGIPTFVLLNTTGILLPARVDHLELLSISGEPLKTLPVKYYPDRKPYGLWNISDFIPPDEAFFLKIMGYDKDGYIFQRVSSVSFSSITPDAPKVTMPNKTPGYYSQPGSVPCHVESLIPFTQHFTKNGVKLGVDQLFKESSSMSWDINRVSLSDEGFYECIANSTAGTGHAQTFLDVSEPPPVIQVPNNVTAVLREGAILTCLVVSTMRYNLTWQRNGRDVRLQEPLRMRVMSNLSLEVKAVQFTDAGKYNCVASNKDGSTTASVFLTVQEPPRIVISPKDQTFVEGSEVSIRCSATGYPKPTVVWTHNEMFIIGSNRYRLTPEGTLIIRQAIPKDAGVYGCLASNSAGTEKQTSILTYIEGPTVTIFQSEILVALGDTTVMECKTTGIPHPQVKWFKGDLELRASAFLIIDTHRGLLKIQETQELDAGDYTCVATNDAGRASGKITLDVGSPPVFIQEPSDESVDIGSNITLPCYVQGYPEPKVKWRRLNGASLFSRPLAVSFISQLRTGALSINNLWVNDEGSYVCEAENQFGRIQSQPATITVTGLVAPLIGISPATANVIEGQQLTLPCVLLAGNPIPDRKWIKNSMVLVSNPYINVRSDGSLHLERVRLQDGGDYTCMASNVAGTNNKTTTVNVYVLPIVQHGQQIFSTIEGIPVTLPCKASGVPKPSITWSKKGEVIFPSNEKFSAGSDGSLYVVSPEGEETGEYVCTATNAAGYATRKVQLTVYVKPRVSRPGDQQGHGPVEISVITGDDVTLPCEVKSLPPPIITWAKETQLISPFSLRHTFLLSGSMKISETQVSDSGMYFCVATNIAGNVTQSVKLSVHVPPKIQRGPQIMKVQAGHRVDIPCSAQGNPPPAITWFRGSSAVPIGSGQPTHSLGGALSISNVQLSNAGIYRCIASNAAGSDTSEITIQVQEPPTMDDLDPQYNNPFQERVVNQRIAFPCPVKGTPKPVIKWLHNGRELTGREPGISILENDMLLIIASITPSDNGEYICVATNEAGRTERKYNLEVHVPPEIRDQERVTNTSVVVNHPISLFCEVFGNPFPVISWYKEDIQVVESNTLHQILHNGKILKLLKATVDDAGQYSCKAINVAGSSEKLFNLYILVPPSIIGADTPSEIAVILNQETSLECRAKGFPFPGIHWFKDSMPLFLGDPNVELLEKGQVLHIKSARMVDKGHYQCSATNAAGKQIKEVKLIIHVPPSIKGGNITTEVSALLNNLINLDCETKGIPVPTITWYKEGRRIISSPQALYVDRGQFLQIPHAQVSDSAKYTCHVTNAAGAAEKTYEVDVYVPPVIEGDAETAQSRQVVAGNSLTLECKAAGNPSPLLTWLKDGVPVKASDNLRVVSGGKKLEILNAVEADRGQYLCVATSIAGEQEIKYGVEILVPPFVEGGDEFLDYIVVLHSPLELDCSATGTPLPTITWLKGGQPIEEGTGHKILLSGQKFLISRAQVSDTGHYKCVAVNVAGEHEREFVVTVHVPPTIKSAGTSERAVVVHKAVTLQCIANGIPSPSITWLKDGQPVNTARGNTRLESSGRVLQVAEALLEDAGRYTCVAINAAGEAQQHIRLRVHEPPSLEDAGKMLNETVVVNNPIHLECRALGNPLPAITWYKDSHSLTSAASVTFLNKGQVLEIEGAQISDTGIYKCVAVNIAGTAELSYSLQVHVPPSISDSSDTVTAVVNNLVRMECEARGIPAPILTWLKDGSPVSSFSDGLQILSGGRVLVLTSAQISDTGKYTCVAVNAAGESQRDIDLRVYVPPNIMGEEQNVSVLISQAAELLCQSNAVPLPMLMWLKDGRPLLNKPGLSISEDGSVLKIEGAQVQDTGRYTCEATNVAGKTKKNYNVNIWVPPSIYGSDDTSQLTVIEGSLISLICESTGIPPPSLTWKKSGSPLVADQSGRVRILSGGRQLQISVAEMSDAASYICIASNVAGSAKKEYSLQVYTRPVILDSGSYPSEVVAAQGSEISLECKAQGIPEPAVTWMKDGRPLVSGRDVAVLHDGHFLLLRNIQVSDTGHYVCVAANVAGLYDRKYDLNVHVPPDIAGDLQLPENISTVEKNPISLVCEASGIPLPSVMWLKNGWPVTSNTSVQILSGGRTLRLTHTTVSDEGHYTCVVTNAAGEARKDFYLSVLVPPGIVDENKQEDMKVKEKNSVTLTCEVIGNPVPQITWIKDGQPLMEDKDHRFLSSGRFLQITNAQVSDTGRYTCVASNTAGDKSKSYFLNVLVSPTIVGADSHGSAEEVTVILNSPTSLVCEAYSYPPATITWLKDGSLLESNRNIHILPGGRILQILSAQKHSAARYTCIATNEAGETMKHYEVQVYIPPTINRGDVPGMDLSPKEMKIKINHSLTLECEAHAVPAAAISWYKDGQPLKPDDRVIIQASGHTLQITEAQVSDTGRYTCLASNIAGEDEVEFDINIQVPPSFQKPYRGWESGNMVDTGRGGENKDVIINNPLSLYCETDAVPPPVLTWYKDGYPLNSSDKVLILPGGRVFQIPRARAEDAGRYMCAAVNEAGEDSIHYNVHVLLPPSIRGADGDLPEEVNVLGNKVAVMDCVTSGSPSPSITWEKDGHLLAEDNKHSFLSNGRRLQILNSQVTDTGRYVCVVENIAGRAKKYFNLNVHVPPSVVGANPENLTVVVNNLISLTCEVTGFPPPDLSWLKNGKPVSLNTNTFIVPGARTLQIPQAKLSDDGEYTCIARNHAGESQKKSFLTVLVPPGIKDHSGTSVTVFNVRVGTPVMLECKASAIPPPVITWYKNRRMISESANVEILADGQTLQIKGAEVSDTGQYVCKAINIAGRDDKNFHLNVYVPPNIEGPEEELVIETISNPVAFICDATGIPPPTLVWLKNGKPLENSNSLDVHIFSGGSRLQIAHSQLLDSGTYTCIASNVEGKAQKRFVLSVQVPPSIVGSEMPREVGVLLGEGIQLVCNATGVPMPVVQWLKDGKTVASDNLERIRVAPDGSTLNIFRALTSDTGKYTCVATNPAGEEDQIFNLSVYVPPTITNNKSEPEDLAALLESSINIGCAATGMPSPQINWLKNGLPLSVSSRIRLLSAGQILRLVRVQISDAGVYTCVASSRAGVDNKHYNLQIFVPPSLDNARGTEEVTVAKGSSASLKCFTDGAPPPAMSWFKNGHPLSLGAHQNLNNQGMVLHFVEAEIGDVGKYTCVAANKAGDVSKHFSLKVLEPPQINGSGQPEELSVIVNNPLELLCISTGIPIPKISWMKDGRPLLQNDNIHVIREGLRITSAQVKDAGRYTCLAFSPAGDDDKEYLVRVHVPPNIAGTSGVQDLTVLQNRQIILECKSDAVPPPIISWLKNGELLEGTPRIRILSNGRYMQINNADLGDTANYTCVASNIAGKMTREFMLAVHVAPTIRSSPQTTVVHLNSSVVLECTAEGVPTPRIAWRKDGNVFNGNNTRYSILEDGSLQIHSAHVTDTGRYLCMATNAAGTERKQIDLQVLVPPTIASGHTNITVTVNVQTTLPCEATGIPRPAVSWKKNGHLLSLDQNQNTYRLLSSGSLVIISPTVDDTAVYECSVSNDAGEDQRAVELTVQVPPSIADEATDLLVTKLSPVVISCTASGVPVPSVHWTKNGVKLLPRGDGYRILPSGAVEIPAVQLAHAGQYTCVARNAAGSAHRHTTLHVQERPVIQIQPGMLDVIVNNSILLPCEAVGTPRPIITWQKEGINIMTTGNSYMALPNGSLWITESTVEDAGTYTCVAQNLAGTALGKIKLKVQVPPVIKSHLKEYVVPVDQSVTLQCEAEGNPGPEISWHKDGQQVAESMRRRILSTGALQIVFVQPGDTGHYTCIAANVAGSSSSSMELVVQTPPKIHNTEAHYTVTEDSRAVLACMADGIPTPIINWKKDNTLLTETVGKYKTVPGGDLILDNVVPEDSGTYTCTAMNAAGEDTHAVTLVVHVLPAFTELPGDVTLTKGEQLRLACRASGIPVPKITWTFNNNVIPAQHDDVSGHSELVIERVSKDDSGTYACTAENAVGSIRAIGFVYVKEPPVFRGNYHPSRIEPLGGNAMLNCEVRGDPPPTIQWSKEGVGVQTSKRIQQLNNGSLAIYGTVNEDAGDYKCVATNDAGVVERSLTLTLQSPPVITIEPAGTTVEAGATVMLNCQASGEPPPAIRWSRQGHPFVSDDRMTVLSNGSLHIIAAQKEDTSEYECVARNQMGSVLVRVPLTVQVRGGFSDWLEWQPCSVTCGQGVQKRARWCNNPLPANGGRPCEGPDTDVRSCHNKPCPVDGEWSSWLPWGPCSESCGKGTQTRLRLCSSPSPSHGGSHCRGPDVQRQVCSKRRCPVDGKWAPWGSWSACTVSCGGGSSQRTRQCSDPAPQFGGHRCEGNNIQVDFCNSDPCPIHGSWGPWGSWGTCSRSCNGGQVRRYRGCDSPRPSSGGRACAGADMQIQRCGTGLCPVNGNWGPWQTWSQCSASCGGGEQTRTRLCSNPAPLYNGHPCPGDSSQISRCNSQACPGGPSRALGSIIGNINDIEFGIASLNATVTDSPNSESRVIHAKITSIPRSLGPALRKLVSILSPVYWTTAKEVGEAMNGFTLTDAIFKRETQVEFATGEVLRMTHIARGLDSDGALLLDVVVNGHVLQLQPLANVNMKDYTEDYIQTGPGQLYAYSTRLFAVDGVSVPYMWNHTITYDHTKGKMPFLVETLHASSITTEYNPLEETLAFKIHASISKGDHNNQCPAGFELNSSGPYCTDEDECAVRNPCSHTCHNAVGTYHCSCPKGLTIAADGRMCQDINECQESNSCHQHCINTVGSFHCGCDPGYQLKGRKCIDVNECRQNVCRPDQLCKNTRGGYKCIELCPNGMTKAENGTCIDINECHDRTHQCHYNQICENMQGSYRCVCPRGYRSQGLGRPCVDIDECEARDTCQHECRNTLGSYQCACPSGYHLMPNGKTCQDIDECLKQDTGCGASQMCFNMRGSYQCIETSCPPNYQREPHSGFCLKNCPANDLECALSTYALEYKFVSLPFGIAAGQDLIRLVAYTQDQVMHPRTTFLMADEEPTVPFALRDENLKGVVFTTRPLQEPKTYHMRVRALSYSVDGNIEYQTTFIVYIAVSAYPY", "length": 5417, "header": "tr|A0A8V0ZAP5-1|A0A8V0ZHJ2_CHICK Computationally mapped isoform of Hemicentin-1 OS=Gallus gallus OX=9031 GN=HMCN1 PE=4 SV=1 CANONICAL=A0A8V0ZHJ2-1" }, "locus": { "chromosome": "8", "start_pos": 10538695, "end_pos": 10347618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051155.1", "url": "https://www.ensembl.org/id/ENSGALT00010051155.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030346.1", "url": "https://www.ensembl.org/id/ENSGALP00010030346.1" } ] } }, { "isoform_ac": "A0A8V0ZGD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2/entry#A0A8V0ZGD7-1", "sequence": { "sequence": "MALGKAQGAGPGAVLLLLLALSSCAAPESGAEAIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLYNFALVPFHDPGIGPVTITTDPKKFQFELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRDHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLTMAVNTWKIPFDPSLKEVTVSLSGPSPAIEIHDPLGKQISKGLGLNELLNIHNSAKVVNVKDPDPGTWTIKTSSSGRHSVRITGLSTIEFRAGFSKKSTLDFKKTSSRPVQGIPTFVLLNTTGILLPARVDHLELLSISGEPLKTLPVKYYPDRKPYGLWNISDFIPPDEAFFLKIMGYDKDGYIFQRVSSVSFSSITPDAPKVTMPNKTPGYYSQPGSVPCHVESLIPFTQHFTKNGVKLGVDQLFKESSSMSWDINRVSLSDEGFYECIANSTAGTGHAQTFLDVSEPPPVIQVPNNVTAVLREGAILTCLVVSTMRYNLTWQRNGRDVRLQEPLRMRVMSNLSLEVKAVQFTDAGKYNCVASNKDGSTTASVFLTVQEPPRIVISPKDQTFVEGSEVSIRCSATGYPKPTVVWTHNEMFIIGSNRYRLTPEGTLIIRQAIPKDAGVYGCLASNSAGTEKQTSILTYIEGPTVTIFQSEILVALGDTTVMECKTTGIPHPQVKWFKGDLELRASAFLIIDTHRGLLKIQETQELDAGDYTCVATNDAGRASGKITLDVGSPPVFIQEPSDESVDIGSNITLPCYVQGYPEPKVKWRRLNGASLFSRPLAVSFISQLRTGALSINNLWVNDEGSYVCEAENQFGRIQSQPATITVTGLVAPLIGISPATANVIEGQQLTLPCVLLAGNPIPDRKWIKNSMVLVSNPYINVRSDGSLHLERVRLQDGGDYTCMASNVAGTNNKTTTVNVYVLPIVQHGQQIFSTIEGIPVTLPCKASGVPKPSITWSKKGEVIFPSNEKFSAGSDGSLYVVSPEGEETGEYVCTATNAAGYATRKVQLTVYVKPRVSRPGDQQGHGPVEISVITGDDVTLPCEVKSLPPPIITWAKETQLISPFSLRHTFLLSGSMKISETQVSDSGMYFCVATNIAGNVTQSVKLSVHVPPKIQRGPQIMKVQAGHRVDIPCSAQGNPPPAITWFRGSSAVPIGSGQPTHSLGGALSISNVQLSNAGIYRCIASNAAGSDTSEITIQVQEPPTMDDLDPQYNNPFQERVVNQRIAFPCPVKGTPKPVIKWLHNGRELTGREPGISILENDMLLIIASITPSDNGEYICVATNEAGRTERKYNLEVHVPPEIRDQERVTNTSVVVNHPISLFCEVFGNPFPVISWYKEDIQVVESNTLHQILHNGKILKLLKATVDDAGQYSCKAINVAGSSEKLFNLYILVPPSIIGADTPSEIAVILNQETSLECRAKGFPFPGIHWFKDSMPLFLGDPNVELLEKGQVLHIKSARMVDKGHYQCSATNAAGKQIKEVKLIIHVPPSIKGGNITTEVSALLNNLINLDCETKGIPVPTITWYKEGRRIISSPQALYVDRGQFLQIPHAQVSDSAKYTCHVTNAAGAAEKTYEVDVYVPPVIEGDAETAQSRQVVAGNSLTLECKAAGNPSPLLTWLKDGVPVKASDNLRVVSGGKKLEILNAVEADRGQYLCVATSIAGEQEIKYGVEILVPPFVEGGDEFLDYIVVLHSPLELDCSATGTPLPTITWLKGGQPIEEGTGHKILLSGQKFLISRAQVSDTGHYKCVAVNVAGEHEREFVVTVHVPPTIKSAGTSERAVVVHKAVTLQCIANGIPSPSITWLKDGQPVNTARGNTRLESSGRVLQVAEALLEDAGRYTCVAINAAGEAQQHIRLRVHEPPSLEDAGKMLNETVVVNNPIHLECRALGNPLPAITWYKDSHSLTSAASVTFLNKGQVLEIEGAQISDTGIYKCVAVNIAGTAELSYSLQVHVPPSISDSSDTVTAVVNNLVRMECEARGIPAPILTWLKDGSPVSSFSDGLQILSGGRVLVLTSAQISDTGKYTCVAVNAAGESQRDIDLRVYVPPNIMGEEQNVSVLISQAAELLCQSNAVPLPMLMWLKDGRPLLNKPGLSISEDGSVLKIEGAQVQDTGRYTCEATNVAGKTKKNYNVNIWVPPSIYGSDDTSQLTVIEGSLISLICESTGIPPPSLTWKKSGSPLVADQSGRVRILSGGRQLQISVAEMSDAASYICIASNVAGSAKKEYSLQVYTRPVILDSGSYPSEVVAAQGSEISLECKAQGIPEPAVTWMKDGRPLVSGRDVAVLHDGHFLLLRNIQVSDTGHYVCVAANVAGLYDRKYDLNVHVPPDIAGDLQLPENISTVEKNPISLVCEASGIPLPSVMWLKNGWPVTSNTSVQILSGGRTLRLTHTTVSDEGHYTCVVTNAAGEARKDFYLSVLVPPGIVDENKQEDMKVKEKNSVTLTCEVIGNPVPQITWIKDGQPLMEDKDHRFLSSGRFLQITNAQVSDTGRYTCVASNTAGDKSKSYFLNVLVSPTIVGADSHGSAEEVTVILNSPTSLVCEAYSYPPATITWLKDGSLLESNRNIHILPGGRILQILSAQKHSAARYTCIATNEAGETMKHYEVQVYIPPTINRGDVPGMDLSPKEMKIKINHSLTLECEAHAVPAAAISWYKDGQPLKPDDRVIIQASGHTLQITEAQVSDTGRYTCLASNIAGEDEVEFDINIQVPPSFQKPYRGWESGNMVDTGRGGENKDVIINNPLSLYCETDAVPPPVLTWYKDGYPLNSSDKVLILPGGRVFQIPRARAEDAGRYMCAAVNEAGEDSIHYNVHVLLPPSIRGADGDLPEEVNVLGNKVAVMDCVTSGSPSPSITWEKDGHLLAEDNKHSFLSNGRRLQILNSQVTDTGRYVCVVENIAGRAKKYFNLNVHVPPSVVGANPENLTVVVNNLISLTCEVTGFPPPDLSWLKNGKPVSLNTNTFIVPGARTLQIPQAKLSDDGEYTCIARNHAGESQKKSFLTVLVPPGIKDHSGTSVTVFNVRVGTPVMLECKASAIPPPVITWYKNRRMISESANVEILADGQTLQIKGAEVSDTGQYVCKAINIAGRDDKNFHLNVYVPPNIEGPEEELVIETISNPVAFICDATGIPPPTLVWLKNGKPLENSNSLDVHIFSGGSRLQIAHSQLLDSGTYTCIASNVEGKAQKRFVLSVQVPPSIVGSEMPREVGVLLGEGIQLVCNATGVPMPVVQWLKDGKTVASDNLERIRVAPDGSTLNIFRALTSDTGKYTCVATNPAGEEDQIFNLSVYVPPTITNNKSEPEDLAALLESSINIGCAATGMPSPQINWLKNGLPLSVSSRIRLLSAGQILRLVRVQISDAGVYTCVASSRAGVDNKHYNLQIFVPPSLDNARGTEEVTVAKGSSASLKCFTDGAPPPAMSWFKNGHPLSLGAHQNLNNQGMVLHFVEAEIGDVGKYTCVAANKAGDVSKHFSLKVLEPPQINGSGQPEELSVIVNNPLELLCISTGIPIPKISWMKDGRPLLQNDNIHVIREGLRITSAQVKDAGRYTCLAFSPAGDDDKEYLVRVHVPPNIAGTSGVQDLTVLQNRQIILECKSDAVPPPIISWLKNGELLEGTPRIRILSNGRYMQINNADLGDTANYTCVASNIAGKMTREFMLAVHVAPTIRSSPQTTVVHLNSSVVLECTAEGVPTPRIAWRKDGNVFNGNNTRYSILEDGSLQIHSAHVTDTGRYLCMATNAAGTERKQIDLQVLVPPTIASGHTNITVTVNVQTTLPCEATGIPRPAVSWKKNGHLLSLDQNQNTYRLLSSGSLVIISPTVDDTAVYECSVSNDAGEDQRAVELTVQVPPSIADEATDLLVTKLSPVVISCTASGVPVPSVHWTKNGVKLLPRGDGYRILPSGAVEIPAVQLAHAGQYTCVARNAAGSAHRHTTLHVQERPVIQIQPGMLDVIVNNSILLPCEAVGTPRPIITWQKEGINIMTTGNSYMALPNGSLWITESTVEDAGTYTCVAQNLAGTALGKIKLKVQVPPVIKSHLKEYVVPVDQSVTLQCEAEGNPGPEISWHKDGQQVAESMRRRILSTGALQIVFVQPGDTGHYTCIAANVAGSSSSSMELVVQTPPKIHNTEAHYTVTEDSRAVLACMADGIPTPIINWKKDNTLLTETVGKYKTVPGGDLILDNVVPEDSGTYTCTAMNAAGEDTHAVTLVVHVLPAFTELPGDVTLTKGEQLRLACRASGIPVPKITWTFNNNVIPAQHDDVSGHSELVIERVSKDDSGTYACTAENAVGSIRAIGFVYVKEPPVFRGNYHPSRIEPLGGNAMLNCEVRGDPPPTIQWSKEGVGVQTSKRIQQLNNGSLAIYGTVNEDAGDYKCVATNDAGVVERSLTLTLQSPPVITIEPAGTTVEAGATVMLNCQASGEPPPAIRWSRQGHPFVSDDRMTVLSNGSLHIIAAQKEDTSEYECVARNQMGSVLVRVPLTVQVRGGFSDWLEWQPCSVTCGQGVQKRARWCNNPLPANGGRPCEGPDTDVRSCHNKPCPVDGEWSSWLPWGPCSESCGKGTQTRLRLCSSPSPSHGGSHCRGPDVQRQVCSKRRCPVDGKWAPWGSWSACTVSCGGGSSQRTRQCSDPAPQFGGHRCEGNNIQVDFCNSDPCPIHGSWGPWGSWGTCSRSCNGGQVRRYRGCDSPRPSSGGRACAGADMQIQRCGTGLCPVNGNWGPWQTWSQCSASCGGGEQTRTRLCSNPAPLYNGHPCPGDSSQISRCNSQACPGGPSRALGSIIGNINDIEFGIASLNATVTDSPNSESRVIHAKITSIPRSLGPALRKLVSILSPVYWTTAKEVGEAMNGFTLTDAIFKRETQVEFATGEVLRMTHIARGLDSDGALLLDVVVNGHVLQLQPLANVNMKDYTEDYIQTGPGQLYAYSTRLFAVDGVSVPYMWNHTITYDHTKGKMPFLVETLHASSITTEYNPLEETLAFKIHASISKGDHNNQCPAGFELNSSGPYCTDEDECAVRNPCSHTCHNAVGTYHCSCPKGLTIAADGRMCQDINECQESNSCHQHCINTVGSFHCGCDPGYQLKGRKCIDINECHDRTHQCHYNQICENMQGSYRCVCPRGYRSQGLGRPCVDIDECLKQDTGCGASQMCFNMRGSYQCIETSCPPNYQREPHSGFCLKNCPANDLECALSTYALEYKFVSLPFGIAAGQDLIRLVAYTQDQVMHPRTTFLMADEEPTVPFALRDENLKGVVFTTRPLQEPKTYHMRVRALSYSVDGNIEYQTTFIVYIAVSAYPY", "length": 5335, "header": "tr|A0A8V0ZGD7-1|A0A8V0ZGD7_CHICK Computationally mapped isoform of Hemicentin 1 OS=Gallus gallus OX=9031 GN=HMCN1 PE=4 SV=1 CANONICAL=A0A8V0ZHJ2-1" }, "locus": { "chromosome": "8", "start_pos": 10538695, "end_pos": 10347618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051152.1", "url": "https://www.ensembl.org/id/ENSGALT00010051152.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030343.1", "url": "https://www.ensembl.org/id/ENSGALP00010030343.1" } ] } }, { "isoform_ac": "A0A8V0ZHJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2/entry#A0A8V0ZHJ2-1", "sequence": { "sequence": "MALGKAQGAGPGAVLLLLLALSSCAAPESGAEAIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLYNFALVPFHDPGIGPVTITTDPKKFQFELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRDHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLTMAVNTWKIPFDPSLKEVTVSLSGPSPAIEIHDPLGKQISKGLGLNELLNIHNSAKVVNVKDPDPGTWTIKTSSSGRHSVRITGLSTIEFRAGFSKKSTLDFKKTSSRPVQGIPTFVLLNTTGILLPARVDHLELLSISGEPLKTLPVKYYPDRKPYGLWNISDFIPPDEAFFLKIMGYDKDGYIFQRVSSVSFSSITPDAPKVTMPNKTPGYYSQPGSVPCHVESLIPFTQHFTKNGVKLGVDQLFKESSSMSWDINRVSLSDEGFYECIANSTAGTGHAQTFLDVSEPPPVIQVPNNVTAVLREGAILTCLVVSTMRYNLTWQRNGRDVRLQEPLRMRVMSNLSLEVKAVQFTDAGKYNCVASNKDGSTTASVFLTVQEPPRIVISPKDQTFVEGSEVSIRCSATGYPKPTVVWTHNEMFIIGSNRYRLTPEGTLIIRQAIPKDAGVYGCLASNSAGTEKQTSILTYIEGPTVTIFQSEILVALGDTTVMECKTTGIPHPQVKWFKGDLELRASAFLIIDTHRGLLKIQETQELDAGDYTCVATNDAGRASGKITLDVGSPPVFIQEPSDESVDIGSNITLPCYVQGYPEPKVKWRRLNGASLFSRPLAVSFISQLRTGALSINNLWVNDEGSYVCEAENQFGRIQSQPATITVTGLVAPLIGISPATANVIEGQQLTLPCVLLAGNPIPDRKWIKNSMVLVSNPYINVRSDGSLHLERVRLQDGGDYTCMASNVAGTNNKTTTVNVYVLPIVQHGQQIFSTIEGIPVTLPCKASGVPKPSITWSKKGEVIFPSNEKFSAGSDGSLYVVSPEGEETGEYVCTATNAAGYATRKVQLTVYVKPRVSRPGDQQGHGPVEISVITGDDVTLPCEVKSLPPPIITWAKETQLISPFSLRHTFLLSGSMKISETQVSDSGMYFCVATNIAGNVTQSVKLSVHVPPKIQRGPQIMKVQAGHRVDIPCSAQGNPPPAITWFRGSSAVPIGSGQPTHSLGGALSISNVQLSNAGIYRCIASNAAGSDTSEITIQVQEPPTMDDLDPQYNNPFQERVVNQRIAFPCPVKGTPKPVIKWLHNGRELTGREPGISILENDMLLIIASITPSDNGEYICVATNEAGRTERKYNLEVHVPPEIRDQERVTNTSVVVNHPISLFCEVFGNPFPVISWYKEDIQVVESNTLHQILHNGKILKLLKATVDDAGQYSCKAINVAGSSEKLFNLYILVPPSIIGADTPSEIAVILNQETSLECRAKGFPFPGIHWFKDSMPLFLGDPNVELLEKGQVLHIKSARMVDKGHYQCSATNAAGKQIKEVKLIIHVPPSIKGGNITTEVSALLNNLINLDCETKGIPVPTITWYKEGRRIISSPQALYVDRGQFLQIPHAQVSDSAKYTCHVTNAAGAAEKTYEVDVYVPPVIEGDAETAQSRQVVAGNSLTLECKAAGNPSPLLTWLKDGVPVKASDNLRVVSGGKKLEILNAVEADRGQYLCVATSIAGEQEIKYGVEILVPPFVEGGDEFLDYIVVLHSPLELDCSATGTPLPTITWLKGGQPIEEGTGHKILLSGQKFLISRAQVSDTGHYKCVAVNVAGEHEREFVVTVHVPPTIKSAGTSERAVVVHKAVTLQCIANGIPSPSITWLKDGQPVNTARGNTRLESSGRVLQVAEALLEDAGRYTCVAINAAGEAQQHIRLRVHEPPSLEDAGKMLNETVVVNNPIHLECRALGNPLPAITWYKDSHSLTSAASVTFLNKGQVLEIEGAQISDTGIYKCVAVNIAGTAELSYSLQVHVPPSISDSSDTVTAVVNNLVRMECEARGIPAPILTWLKDGSPVSSFSDGLQILSGGRVLVLTSAQISDTGKYTCVAVNAAGESQRDIDLRVYVPPNIMGEEQNVSVLISQAAELLCQSNAVPLPMLMWLKDGRPLLNKPGLSISEDGSVLKIEGAQVQDTGRYTCEATNVAGKTKKNYNVNIWVPPSIYGSDDTSQLTVIEGSLISLICESTGIPPPSLTWKKSGSPLVADQSGRVRILSGGRQLQISVAEMSDAASYICIASNVAGSAKKEYSLQVYTRPVILDSGSYPSEVVAAQGSEISLECKAQGIPEPAVTWMKDGRPLVSGRDVAVLHDGHFLLLRNIQVSDTGHYVCVAANVAGLYDRKYDLNVHVPPDIAGDLQLPENISTVEKNPISLVCEASGIPLPSVMWLKNGWPVTSNTSVQILSGGRTLRLTHTTVSDEGHYTCVVTNAAGEARKDFYLSVLVPPGIVDENKQEDMKVKEKNSVTLTCEVIGNPVPQITWIKDGQPLMEDKDHRFLSSGRFLQITNAQVSDTGRYTCVASNTAGDKSKSYFLNVLVSPTIVGADSHGSAEEVTVILNSPTSLVCEAYSYPPATITWLKDGSLLESNRNIHILPGGRILQILSAQKHSAARYTCIATNEAGETMKHYEVQVYIPPTINRGDVPGMDLSPKEMKIKINHSLTLECEAHAVPAAAISWYKDGQPLKPDDRVIIQASGHTLQITEAQVSDTGRYTCLASNIAGEDEVEFDINIQVPPSFQKPYRGWESGNMVDTGRGGENKDVIINNPLSLYCETDAVPPPVLTWYKDGYPLNSSDKVLILPGGRVFQIPRARAEDAGRYMCAAVNEAGEDSIHYNVHVLLPPSIRGADGDLPEEVNVLGNKVAVMDCVTSGSPSPSITWEKDGHLLAEDNKHSFLSNGRRLQILNSQVTDTGRYVCVVENIAGRAKKYFNLNVHVPPSVVGANPENLTVVVNNLISLTCEVTGFPPPDLSWLKNGKPVSLNTNTFIVPGARTLQIPQAKLSDDGEYTCIARNHAGESQKKSFLTVLVPPGIKDHSGTSVTVFNVRVGTPVMLECKASAIPPPVITWYKNRRMISESANVEILADGQTLQIKGAEVSDTGQYVCKAINIAGRDDKNFHLNVYVPPNIEGPEEELVIETISNPVAFICDATGIPPPTLVWLKNGKPLENSNSLDVHIFSGGSRLQIAHSQLLDSGTYTCIASNVEGKAQKRFVLSVQVPPSIVGSEMPREVGVLLGEGIQLVCNATGVPMPVVQWLKDGKTVASDNLERIRVAPDGSTLNIFRALTSDTGKYTCVATNPAGEEDQIFNLSVYVPPTITNNKSEPEDLAALLESSINIGCAATGMPSPQINWLKNGLPLSVSSRIRLLSAGQILRLVRVQISDAGVYTCVASSRAGVDNKHYNLQIFVPPSLDNARGTEEVTVAKGSSASLKCFTDGAPPPAMSWFKNGHPLSLGAHQNLNNQGMVLHFVEAEIGDVGKYTCVAANKAGDVSKHFSLKVLEPPQINGSGQPEELSVIVNNPLELLCISTGIPIPKISWMKDGRPLLQNDNIHVIREGLRITSAQVKDAGRYTCLAFSPAGDDDKEYLVRVHVPPNIAGTSGVQDLTVLQNRQIILECKSDAVPPPIISWLKNGELLEGTPRIRILSNGRYMQINNADLGDTANYTCVASNIAGKMTREFMLAVHVAPTIRSSPQTTVVHLNSSVVLECTAEGVPTPRIAWRKDGNVFNGNNTRYSILEDGSLQIHSAHVTDTGRYLCMATNAAGTERKQIDLQVLVPPTIASGHTNITVTVNVQTTLPCEATGIPRPAVSWKKNGHLLSLDQNQNTYRLLSSGSLVIISPTVDDTAVYECSVSNDAGEDQRAVELTVQVPPSIADEATDLLVTKLSPVVISCTASGVPVPSVHWTKNGVKLLPRGDGYRILPSGAVEIPAVQLAHAGQYTCVARNAAGSAHRHTTLHVQERPVIQIQPGMLDVIVNNSILLPCEAVGTPRPIITWQKEGINIMTTGNSYMALPNGSLWITESTVEDAGTYTCVAQNLAGTALGKIKLKVQVPPVIKSHLKEYVVPVDQSVTLQCEAEGNPGPEISWHKDGQQVAESMRRRILSTGALQIVFVQPGDTGHYTCIAANVAGSSSSSMELVVQTPPKIHNTEAHYTVTEDSRAVLACMADGIPTPIINWKKDNTLLTETVGKYKTVPGGDLILDNVVPEDSGTYTCTAMNAAGEDTHAVTLVVHVLPAFTELPGDVTLTKGEQLRLACRASGIPVPKITWTFNNNVIPAQHDDVSGHSELVIERVSKDDSGTYACTAENAVGSIRAIGFVYVKEPPVFRGNYHPSRIEPLGGNAMLNCEVRGDPPPTIQWSKEGVGVQTSKRIQQLNNGSLAIYGTVNEDAGDYKCVATNDAGVVERSLTLTLQSPPVITIEPAGTTVEAGATVMLNCQASGEPPPAIRWSRQGHPFVSDDRMTVLSNGSLHIIAAQKEDTSEYECVARNQMGSVLVRVPLTVQVRGGFSDWLEWQPCSVTCGQGVQKRARWCNNPLPANGGRPCEGPDTDVRSCHNKPCPVDGEWSSWLPWGPCSESCGKGTQTRLRLCSSPSPSHGGSHCRGPDVQRQVCSKRRCPVDGKWAPWGSWSACTVSCGGGSSQRTRQCSDPAPQFGGHRCEGNNIQVDFCNSDPCPIHGSWGPWGSWGTCSRSCNGGQVRRYRGCDSPRPSSGGRACAGADMQIQRCGTGLCPVNGNWGPWQTWSQCSASCGGGEQTRTRLCSNPAPLYNGHPCPGDSSQISRCNSQACPGGPSRALGSIIGNINDIEFGIASLNATVTDSPNSESRVIHAKITSIPRSLGPALRKLVSILSPVYWTTAKEVGEAMNGFTLTDAIFKRETQVEFATGEVLRMTHIARGLDSDGALLLDVVVNGHVLQLQPLANVNMKDYTEDYIQTGPGQLYAYSTRLFAVDGVSVPYMWNHTITYDHTKGKMPFLVETLHASSITTEYNPLEETLAFKIHASISKGDHNNQCPAGFELNSSGPYCTDEDECAVRNPCSHTCHNAVGTYHCSCPKGLTIAADGRMCQDVDECVLGRHACHTDQDCENSAGSYHCVLRCRTGFRRAVDGLSCQDINECQESNSCHQHCINTVGSFHCGCDPGYQLKGRKCIDVNECRQNVCRPDQLCKNTRGGYKCIELCPNGMTKAENGTCIDINECHDRTHQCHYNQICENMQGSYRCVCPRGYRSQGLGRPCVDINECEQVPKPCAFQCTNTPGSFKCICPPGQHLLGDGKSCAGLERLLHSGAYYNIYNYAQFSPIRDNYQPQRSYRHSSNLYSSFSEYRNSRIPVSRTKRSIRETCPEGYEARNDRCVDIDECEARDTCQHECRNTLGSYQCACPSGYHLMPNGKTCQDIDECLKQDTGCGASQMCFNMRGSYQCIETSCPPNYQREPHSGFCLKNCPANDLECALSTYALEYKFVSLPFGIAAGQDLIRLVAYTQDQVMHPRTTFLMADEEPTVPFALRDENLKGVVFTTRPLQEPKTYHMRVRALSYSVDGNIEYQTTFIVYIAVSAYPY", "length": 5579, "header": "tr|A0A8V0ZHJ2-1|A0A8V0ZHJ2_CHICK Isoform 1 of Hemicentin-1 OS=Gallus gallus OX=9031 GN=HMCN1 PE=4 SV=1 CANONICAL=A0A8V0ZHJ2-1" }, "locus": { "chromosome": "8", "start_pos": 10538695, "end_pos": 10347618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051098.1", "url": "https://www.ensembl.org/id/ENSGALT00010051098.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030289.1", "url": "https://www.ensembl.org/id/ENSGALP00010030289.1" } ] } }, { "isoform_ac": "A0A8V0ZHN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2/entry#A0A8V0ZHN4-1", "sequence": { "sequence": "MALGKAQGAGPGAVLLLLLALSSCAAPESGAEAIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLYNFALVPFHDPGIGPVTITTDPKKFQFELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRDHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLTMAVNTWKIPFDPSLKEVTVSLSGPSPAIEIHDPLGKQISKGLGLNELLNIHNSAKVVNVKDPDPGTWTIKTSSSGRHSVRITGLSTIEFRAGFSKKSTLDFKKTSSRPVQGIPTFVLLNTTGILLPARVDHLELLSISGEPLKTLPVKYYPDRKPYGLWNISDFIPPDEAFFLKIMGYDKDGYIFQRVSSVSFSSITPDAPKVTMPNKTPGYYSQPGSVPCHVESLIPFTQHFTKNGVKLGVDQLFKESSSMSWDINRVSLSDEGFYECIANSTAGTGHAQTFLDVSEPPPVIQVPNNVTAVLREGAILTCLVVSTMRYNLTWQRNGRDVRLQEPLRMRVMSNLSLEVKAVQFTDAGKYNCVASNKDGSTTASVFLTVQEPPRIVISPKDQTFVEGSEVSIRCSATGYPKPTVVWTHNEMFIIGSNRYRLTPEGTLIIRQAIPKDAGVYGCLASNSAGTEKQTSILTYIEGPTVTIFQSEILVALGDTTVMECKTTGIPHPQVKWFKGDLELRASAFLIIDTHRGLLKIQETQELDAGDYTCVATNDAGRASGKITLDVGSPPVFIQEPSDESVDIGSNITLPCYVQGYPEPKVKWRRLNGASLFSRPLAVSFISQLRTGALSINNLWVNDEGSYVCEAENQFGRIQSQPATITVTGLVAPLIGISPATANVIEGQQLTLPCVLLAGNPIPDRKWIKNSMVLVSNPYINVRSDGSLHLERVRLQDGGDYTCMASNVAGTNNKTTTVNVYVLPIVQHGQQIFSTIEGIPVTLPCKASGVPKPSITWSKKGEVIFPSNEKFSAGSDGSLYVVSPEGEETGEYVCTATNAAGYATRKVQLTVYVKPRVSRPGDQQGHGPVEISVITGDDVTLPCEVKSLPPPIITWAKETQLISPFSLRHTFLLSGSMKISETQVSDSGMYFCVATNIAGNVTQSVKLSVHVPPKIQRGPQIMKVQAGHRVDIPCSAQGNPPPAITWFRGSSAVPIGSGQPTHSLGGALSISNVQLSNAGIYRCIASNAAGSDTSEITIQVQEPPTMDDLDPQYNNPFQERVVNQRIAFPCPVKGTPKPVIKWLHNGRELTGREPGISILENDMLLIIASITPSDNGEYICVATNEAGRTERKYNLEVHVPPEIRDQERVTNTSVVVNHPISLFCEVFGNPFPVISWYKEDIQVVESNTLHQILHNGKILKLLKATVDDAGQYSCKAINVAGSSEKLFNLYILVPPSIIGADTPSEIAVILNQETSLECRAKGFPFPGIHWFKDSMPLFLGDPNVELLEKGQVLHIKSARMVDKGHYQCSATNAAGKQIKEVKLIIHVPPSIKGGNITTEVSALLNNLINLDCETKGIPVPTITWYKEGRRIISSPQALYVDRGQFLQIPHAQVSDSAKYTCHVTNAAGAAEKTYEVDVYVPPVIEGDAETAQSRQVVAGNSLTLECKAAGNPSPLLTWLKDGVPVKASDNLRVVSGGKKLEILNAVEADRGQYLCVATSIAGEQEIKYGVEILVPPFVEGGDEFLDYIVVLHSPLELDCSATGTPLPTITWLKGGQPIEEGTGHKILLSGQKFLISRAQVSDTGHYKCVAVNVAGEHEREFVVTVHVPPTIKSAGTSERAVVVHKAVTLQCIANGIPSPSITWLKDGQPVNTARGNTRLESSGRVLQVAEALLEDAGRYTCVAINAAGEAQQHIRLRVHEPPSLEDAGKMLNETVVVNNPIHLECRALGNPLPAITWYKDSHSLTSAASVTFLNKGQVLEIEGAQISDTGIYKCVAVNIAGTAELSYSLQVHVPPSISDSSDTVTAVVNNLVRMECEARGIPAPILTWLKDGSPVSSFSDGLQILSGGRVLVLTSAQISDTGKYTCVAVNAAGESQRDIDLRVYVPPNIMGEEQNVSVLISQAAELLCQSNAVPLPMLMWLKDGRPLLNKPGLSISEDGSVLKIEGAQVQDTGRYTCEATNVAGKTKKNYNVNIWVPPSIYGSDDTSQLTVIEGSLISLICESTGIPPPSLTWKKSGSPLVADQSGRVRILSGGRQLQISVAEMSDAASYICIASNVAGSAKKEYSLQVYTRPVILDSGSYPSEVVAAQGSEISLECKAQGIPEPAVTWMKDGRPLVSGRDVAVLHDGHFLLLRNIQVSDTGHYVCVAANVAGLYDRKYDLNVHVPPDIAGDLQLPENISTVEKNPISLVCEASGIPLPSVMWLKNGWPVTSNTSVQILSGGRTLRLTHTTVSDEGHYTCVVTNAAGEARKDFYLSVLVPPGIVDENKQEDMKVKEKNSVTLTCEVIGNPVPQITWIKDGQPLMEDKDHRFLSSGRFLQITNAQVSDTGRYTCVASNTAGDKSKSYFLNVLVSPTIVGADSHGSAEEVTVILNSPTSLVCEAYSYPPATITWLKDGSLLESNRNIHILPGGRILQILSAQKHSAARYTCIATNEAGETMKHYEVQVYIPPTINRGDVPGMDLSPKEMKIKINHSLTLECEAHAVPAAAISWYKDGQPLKPDDRVIIQASGHTLQITEAQVSDTGRYTCLASNIAGEDEVEFDINIQVPPSFQKPYRGWESGNMVDTGRGGENKDVIINNPLSLYCETDAVPPPVLTWYKDGYPLNSSDKVLILPGGRVFQIPRARAEDAGRYMCAAVNEAGEDSIHYNVHVLLPPSIRGADGDLPEEVNVLGNKVAVMDCVTSGSPSPSITWEKDGHLLAEDNKHSFLSNGRRLQILNSQVTDTGRYVCVVENIAGRAKKYFNLNVHVPPSVVGANPENLTVVVNNLISLTCEVTGFPPPDLSWLKNGKPVSLNTNTFIVPGARTLQIPQAKLSDDGEYTCIARNHAGESQKKSFLTVLVPPGIKDHSGTSVTVFNVRVGTPVMLECKASAIPPPVITWYKNRRMISESANVEILADGQTLQIKGAEVSDTGQYVCKAINIAGRDDKNFHLNVYVPPNIEGPEEELVIETISNPVAFICDATGIPPPTLVWLKNGKPLENSNSLDVHIFSGGSRLQIAHSQLLDSGTYTCIASNVEGKAQKRFVLSVQVPPSIVGSEMPREVGVLLGEGIQLVCNATGVPMPVVQWLKDGKTVASDNLERIRVAPDGSTLNIFRALTSDTGKYTCVATNPAGEEDQIFNLSVYVPPTITNNKSEPEDLAALLESSINIGCAATGMPSPQINWLKNGLPLSVSSRIRLLSAGQILRLVRVQISDAGVYTCVASSRAGVDNKHYNLQIFVPPSLDNARGTEEVTVAKGSSASLKCFTDGAPPPAMSWFKNGHPLSLGAHQNLNNQGMVLHFVEAEIGDVGKYTCVAANKAGDVSKHFSLKVLEPPQINGSGQPEELSVIVNNPLELLCISTGIPIPKISWMKDGRPLLQNDNIHVIREGLRITSAQVKDAGRYTCLAFSPAGDDDKEYLVRVHVPPNIAGTSGVQDLTVLQNRQIILECKSDAVPPPIISWLKNGELLEGTPRIRILSNGRYMQINNADLGDTANYTCVASNIAGKMTREFMLAVHVAPTIRSSPQTTVVHLNSSVVLECTAEGVPTPRIAWRKDGNVFNGNNTRYSILEDGSLQIHSAHVTDTGRYLCMATNAAGTERKQIDLQVLVPPTIASGHTNITVTVNVQTTLPCEATGIPRPAVSWKKNGHLLSLDQNQNTYRLLSSGSLVIISPTVDDTAVYECSVSNDAGEDQRAVELTVQVPPSIADEATDLLVTKLSPVVISCTASGVPVPSVHWTKNGVKLLPRGDGYRILPSGAVEIPAVQLAHAGQYTCVARNAAGSAHRHTTLHVQERPVIQIQPGMLDVIVNNSILLPCEAVGTPRPIITWQKEGINIMTTGNSYMALPNGSLWITESTVEDAGTYTCVAQNLAGTALGKIKLKVQVPPVIKSHLKEYVVPVDQSVTLQCEAEGNPGPEISWHKDGQQVAESMRRRILSTGALQIVFVQPGDTGHYTCIAANVAGSSSSSMELVVQTPPKIHNTEAHYTVTEDSRAVLACMADGIPTPIINWKKDNTLLTETVGKYKTVPGGDLILDNVVPEDSGTYTCTAMNAAGEDTHAVTLVVHVLPAFTELPGDVTLTKGEQLRLACRASGIPVPKITWTFNNNVIPAQHDDVSGHSELVIERVSKDDSGTYACTAENAVGSIRAIGFVYVKEPPVFRGNYHPSRIEPLGGNAMLNCEVRGDPPPTIQWSKEGVGVQTSKRIQQLNNGSLAIYGTVNEDAGDYKCVATNDAGVVERSLTLTLQSPPVITIEPAGTTVEAGATVMLNCQASGEPPPAIRWSRQGHPFVSDDRMTVLSNGSLHIIAAQKEDTSEYECVARNQMGSVLVRVPLTVQVRGGFSDWLEWQPCSVTCGQGVQKRARWCNNPLPANGGRPCEGPDTDVRSCHNKPCPVDGEWSSWLPWGPCSESCGKGTQTRLRLCSSPSPSHGGSHCRGPDVQRQVCSKRRCPVDGKWAPWGSWSACTVSCGGGSSQRTRQCSDPAPQFGGHRCEGNNIQVDFCNSDPCPIHGSWGPWGSWGTCSRSCNGGQVRRYRGCDSPRPSSGGRACAGADMQIQRCGTGLCPVNGNWGPWQTWSQCSASCGGGEQTRTRLCSNPAPLYNGHPCPGDSSQISRCNSQACPGGPSRALGSIIGNINDIEFGIASLNATVTDSPNSESRVIHAKITSIPRSLGPALRKLVSILSPVYWTTAKEVGEAMNGFTLTDAIFKRETQVEFATGEVLRMTHIARGLDSDGALLLDVVVNGHVLQLQPLANVNMKDYTEDYIQTGPGQLYAYSTRLFAVDGVSVPYMWNHTITYDHTKGKMPFLVETLHASSITTEYNPLEETLAFKIHASISKGDHNNQCPAGFELNSSGPYCTDEDECAVRNPCSHTCHNAVGTYHCSCPKGLTIAADGRMCQDVDECVLGRHACHTDQDCENSAGSYHCVLRCRTGFRRAVDGLSCQDINECQESNSCHQHCINTVGSFHCGCDPGYQLKGRKCIDVNECRQNVCRPDQLCKNTRGGYKCIELCPNGMTKAENGTCIDINECHDRTHQCHYNQICENMQGSYRCVCPRGYRSQGLGRPCVDIDECEARDTCQHECRNTLGSYQCACPSGYHLMPNGKTCQDIDECLKQDTGCGASQMCFNMRGSYQCIETSCPPNYQREPHSGFCLKNCPANDLECALSTYALEYKFVSLPFGIAAGQDLIRLVAYTQDQVMHPRTTFLMADEEPTVPFALRDENLKGVVFTTRPLQEPKTYHMRVRALSYSVDGNIEYQTTFIVYIAVSAYPY", "length": 5462, "header": "tr|A0A8V0ZHN4-1|A0A8V0ZHN4_CHICK Computationally mapped isoform of Hemicentin-1 OS=Gallus gallus OX=9031 GN=HMCN1 PE=4 SV=1 CANONICAL=A0A8V0ZHJ2-1" }, "locus": { "chromosome": "8", "start_pos": 10538695, "end_pos": 10347618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051117.1", "url": "https://www.ensembl.org/id/ENSGALT00010051117.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030308.1", "url": "https://www.ensembl.org/id/ENSGALP00010030308.1" } ] } }, { "isoform_ac": "A0A8V0ZHQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2/entry#A0A8V0ZHQ9-1", "sequence": { "sequence": "MALGKAQGAGPGAVLLLLLALSSCAAPESGAEAIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLYNFALVPFHDPGIGPVTITTDPKKFQFELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRDHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLTMAVNTWKIPFDPSLKEVTVSLSGPSPAIEIHDPLGKQISKGLGLNELLNIHNSAKVVNVKDPDPGTWTIKTSSSGRHSVRITGLSTIEFRAGFSKKSTLDFKKTSSRPVQGIPTFVLLNTTGILLPARVDHLELLSISGEPLKTLPVKYYPDRKPYGLWNISDFIPPDEAFFLKIMGYDKDGYIFQRVSSVSFSSITPDAPKVTMPNKTPGYYSQPGSVPCHVESLIPFTQHFTKNGVKLGVDQLFKESSSMSWDINRVSLSDEGFYECIANSTAGTGHAQTFLDVSEPPPVIQVPNNVTAVLREGAILTCLVVSTMRYNLTWQRNGRDVRLQEPLRMRVMSNLSLEVKAVQFTDAGKYNCVASNKDGSTTASVFLTVQEPPRIVISPKDQTFVEGSEVSIRCSATGYPKPTVVWTHNEMFIIGSNRYRLTPEGTLIIRQAIPKDAGVYGCLASNSAGTEKQTSILTYIEGPTVTIFQSEILVALGDTTVMECKTTGIPHPQVKWFKGDLELRASAFLIIDTHRGLLKIQETQELDAGDYTCVATNDAGRASGKITLDVGSPPVFIQEPSDESVDIGSNITLPCYVQGYPEPKVKWRRLNGASLFSRPLAVSFISQLRTGALSINNLWVNDEGSYVCEAENQFGRIQSQPATITVTGLVAPLIGISPATANVIEGQQLTLPCVLLAGNPIPDRKWIKNSMVLVSNPYINVRSDGSLHLERVRLQDGGDYTCMASNVAGTNNKTTTVNVYVLPIVQHGQQIFSTIEGIPVTLPCKASGVPKPSITWSKKGEVIFPSNEKFSAGSDGSLYVVSPEGEETGEYVCTATNAAGYATRKVQLTVYVKPRVSRPGDQQGHGPVEISVITGDDVTLPCEVKSLPPPIITWAKETQLISPFSLRHTFLLSGSMKISETQVSDSGMYFCVATNIAGNVTQSVKLSVHVPPKIQRGPQIMKVQAGHRVDIPCSAQGNPPPAITWFRGSSAVPIGSGQPTHSLGGALSISNVQLSNAGIYRCIASNAAGSDTSEITIQVQEPPTMDDLDPQYNNPFQERVVNQRIAFPCPVKGTPKPVIKWLHNGRELTGREPGISILENDMLLIIASITPSDNGEYICVATNEAGRTERKYNLEVHVPPEIRDQERVTNTSVVVNHPISLFCEVFGNPFPVISWYKEDIQVVESNTLHQILHNGKILKLLKATVDDAGQYSCKAINVAGSSEKLFNLYILVPPSIIGADTPSEIAVILNQETSLECRAKGFPFPGIHWFKDSMPLFLGDPNVELLEKGQVLHIKSARMVDKGHYQCSATNAAGKQIKEVKLIIHVPPSIKGGNITTEVSALLNNLINLDCETKGIPVPTITWYKEGRRIISSPQALYVDRGQFLQIPHAQVSDSAKYTCHVTNAAGAAEKTYEVDVYVPPVIEGDAETAQSRQVVAGNSLTLECKAAGNPSPLLTWLKDGVPVKASDNLRVVSGGKKLEILNAVEADRGQYLCVATSIAGEQEIKYGVEILVPPFVEGGDEFLDYIVVLHSPLELDCSATGTPLPTITWLKGGQPIEEGTGHKILLSGQKFLISRAQVSDTGHYKCVAVNVAGEHEREFVVTVHVPPTIKSAGTSERAVVVHKAVTLQCIANGIPSPSITWLKDGQPVNTARGNTRLESSGRVLQVAEALLEDAGRYTCVAINAAGEAQQHIRLRVHEPPSLEDAGKMLNETVVVNNPIHLECRALGNPLPAITWYKDSHSLTSAASVTFLNKGQVLEIEGAQISDTGIYKCVAVNIAGTAELSYSLQVHVPPSISDSSDTVTAVVNNLVRMECEARGIPAPILTWLKDGSPVSSFSDGLQILSGGRVLVLTSAQISDTGKYTCVAVNAAGESQRDIDLRVYVPPNIMGEEQNVSVLISQAAELLCQSNAVPLPMLMWLKDGRPLLNKPGLSISEDGSVLKIEGAQVQDTGRYTCEATNVAGKTKKNYNVNIWVPPSIYGSDDTSQLTVIEGSLISLICESTGIPPPSLTWKKSGSPLVADQSGRVRILSGGRQLQISVAEMSDAASYICIASNVAGSAKKEYSLQVYTRPVILDSGSYPSEVVAAQGSEISLECKAQGIPEPAVTWMKDGRPLVSGRDVAVLHDGHFLLLRNIQVSDTGHYVCVAANVAGLYDRKYDLNVHVPPDIAGDLQLPENISTVEKNPISLVCEASGIPLPSVMWLKNGWPVTSNTSVQILSGGRTLRLTHTTVSDEGHYTCVVTNAAGEARKDFYLSVLVPPGIVDENKQEDMKVKEKNSVTLTCEVIGNPVPQITWIKDGQPLMEDKDHRFLSSGRFLQITNAQVSDTGRYTCVASNTAGDKSKSYFLNVLVSPTIVGADSHGSAEEVTVILNSPTSLVCEAYSYPPATITWLKDGSLLESNRNIHILPGGRILQILSAQKHSAARYTCIATNEAGETMKHYEVQVYIPPTINRGDVPGMDLSPKEMKIKINHSLTLECEAHAVPAAAISWYKDGQPLKPDDRVIIQASGHTLQITEAQVSDTGRYTCLASNIAGEDEVEFDINIQVPPSFQKPYRGWESGNMVDTGRGGENKDVIINNPLSLYCETDAVPPPVLTWYKDGYPLNSSDKVLILPGGRVFQIPRARAEDAGRYMCAAVNEAGEDSIHYNVHVLLPPSIRGADGDLPEEVNVLGNKVAVMDCVTSGSPSPSITWEKDGHLLAEDNKHSFLSNGRRLQILNSQVTDTGRYVCVVENIAGRAKKYFNLNVHVPPSVVGANPENLTVVVNNLISLTCEVTGFPPPDLSWLKNGKPVSLNTNTFIVPGARTLQIPQAKLSDDGEYTCIARNHAGESQKKSFLTVLVPPGIKDHSGTSVTVFNVRVGTPVMLECKASAIPPPVITWYKNRRMISESANVEILADGQTLQIKGAEVSDTGQYVCKAINIAGRDDKNFHLNVYVPPNIEGPEEELVIETISNPVAFICDATGIPPPTLVWLKNGKPLENSNSLDVHIFSGGSRLQIAHSQLLDSGTYTCIASNVEGKAQKRFVLSVQVPPSIVGSEMPREVGVLLGEGIQLVCNATGVPMPVVQWLKDGKTVASDNLERIRVAPDGSTLNIFRALTSDTGKYTCVATNPAGEEDQIFNLSVYVPPTITNNKSEPEDLAALLESSINIGCAATGMPSPQINWLKNGLPLSVSSRIRLLSAGQILRLVRVQISDAGVYTCVASSRAGVDNKHYNLQIFVPPSLDNARGTEEVTVAKGSSASLKCFTDGAPPPAMSWFKNGHPLSLGAHQNLNNQGMVLHFVEAEIGDVGKYTCVAANKAGDVSKHFSLKVLEPPQINGSGQPEELSVIVNNPLELLCISTGIPIPKISWMKDGRPLLQNDNIHVIREGLRITSAQVKDAGRYTCLAFSPAGDDDKEYLVRVHVPPNIAGTSGVQDLTVLQNRQIILECKSDAVPPPIISWLKNGELLEGTPRIRILSNGRYMQINNADLGDTANYTCVASNIAGKMTREFMLAVHVAPTIRSSPQTTVVHLNSSVVLECTAEGVPTPRIAWRKDGNVFNGNNTRYSILEDGSLQIHSAHVTDTGRYLCMATNAAGTERKQIDLQVLVPPTIASGHTNITVTVNVQTTLPCEATGIPRPAVSWKKNGHLLSLDQNQNTYRLLSSGSLVIISPTVDDTAVYECSVSNDAGEDQRAVELTVQVPPSIADEATDLLVTKLSPVVISCTASGVPVPSVHWTKNGVKLLPRGDGYRILPSGAVEIPAVQLAHAGQYTCVARNAAGSAHRHTTLHVQERPVIQIQPGMLDVIVNNSILLPCEAVGTPRPIITWQKEGINIMTTGNSYMALPNGSLWITESTVEDAGTYTCVAQNLAGTALGKIKLKVQVPPVIKSHLKEYVVPVDQSVTLQCEAEGNPGPEISWHKDGQQVAESMRRRILSTGALQIVFVQPGDTGHYTCIAANVAGSSSSSMELVVQTPPKIHNTEAHYTVTEDSRAVLACMADGIPTPIINWKKDNTLLTETVGKYKTVPGGDLILDNVVPEDSGTYTCTAMNAAGEDTHAVTLVVHVLPAFTELPGDVTLTKGEQLRLACRASGIPVPKITWTFNNNVIPAQHDDVSGHSELVIERVSKDDSGTYACTAENAVGSIRAIGFVYVKEPPVFRGNYHPSRIEPLGGNAMLNCEVRGDPPPTIQWSKEGVGVQTSKRIQQLNNGSLAIYGTVNEDAGDYKCVATNDAGVVERSLTLTLQSPPVITIEPAGTTVEAGATVMLNCQASGEPPPAIRWSRQGHPFVSDDRMTVLSNGSLHIIAAQKEDTSEYECVARNQMGSVLVRVPLTVQVRGGFSDWLEWQPCSVTCGQGVQKRARWCNNPLPANGGRPCEGPDTDVRSCHNKPCPVDGEWSSWLPWGPCSESCGKGTQTRLRLCSSPSPSHGGSHCRGPDVQRQVCSKRRCPVDGKWAPWGSWSACTVSCGGGSSQRTRQCSDPAPQFGGHRCEGNNIQVDFCNSDPCPIHGSWGPWGSWGTCSRSCNGGQVRRYRGCDSPRPSSGGRACAGADMQIQRCGTGLCPVNGNWGPWQTWSQCSASCGGGEQTRTRLCSNPAPLYNGHPCPGDSSQISRCNSQACPGGPSRALGSIIGNINDIEFGIASLNATVTDSPNSESRVIHAKITSIPRSLGPALRKLVSILSPVYWTTAKEVGEAMNGFTLTDAIFKRETQVEFATGEVLRMTHIARGLDSDGALLLDVVVNGHVLQLQPLANVNMKDYTEDYIQTGPGQLYAYSTRLFAVDGVSVPYMWNHTITYDHTKGKMPFLVETLHASSITTEYNPLEETLAFKIHASISKGDHNNQCPAGFELNSSGPYCTDEDECAVRNPCSHTCHNAVGTYHCSCPKGLTIAADGRMCQDVDECVLGRHACHTDQDCENSAGSYHCVLRCRTGFRRAVDGLSCQDINECQESNSCHQHCINTVGSFHCGCDPGYQLKGRKCIDINECHDRTHQCHYNQICENMQGSYRCVCPRGYRSQGLGRPCVDIDECEARDTCQHECRNTLGSYQCACPSGYHLMPNGKTCQDIDECLKQDTGCGASQMCFNMRGSYQCIETSCPPNYQREPHSGFCLKNCPANDLECALSTYALEYKFVSLPFGIAAGQDLIRLVAYTQDQVMHPRTTFLMADEEPTVPFALRDENLKGVVFTTRPLQEPKTYHMRVRALSYSVDGNIEYQTTFIVYIAVSAYPY", "length": 5420, "header": "tr|A0A8V0ZHQ9-1|A0A8V0ZHQ9_CHICK Computationally mapped isoform of Hemicentin 1 OS=Gallus gallus OX=9031 GN=HMCN1 PE=4 SV=1 CANONICAL=A0A8V0ZHJ2-1" }, "locus": { "chromosome": "8", "start_pos": 10538695, "end_pos": 10347618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051143.1", "url": "https://www.ensembl.org/id/ENSGALT00010051143.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030334.1", "url": "https://www.ensembl.org/id/ENSGALP00010030334.1" } ] } }, { "isoform_ac": "A0A8V0ZNK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2/entry#A0A8V0ZNK5-1", "sequence": { "sequence": "MALGKAQGAGPGAVLLLLLALSSCAAPESGAEAIPEGASTLAFVFDVTGSMYDDLVQVIEGASKILETSLKRPKRPLYNFALVPFHDPGIGPVTITTDPKKFQFELRELYVQGGGDCPEMSIGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRDHIGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLTMAVNTWKIPFDPSLKEVTVSLSGPSPAIEIHDPLGKQISKGLGLNELLNIHNSAKVVNVKDPDPGTWTIKTSSSGRHSVRITGLSTIEFRAGFSKKSTLDFKKTSSRPVQGIPTFVLLNTTGILLPARVDHLELLSISGEPLKTLPVKYYPDRKPYGLWNISDFIPPDEAFFLKIMGYDKDGYIFQRVSSVSFSSITPDAPKVTMPNKTPGYYSQPGSVPCHVESLIPFTQHFTKNGVKLGVDQLFKESSSMSWDINRVSLSDEGFYECIANSTAGTGHAQTFLDVSEPPPVIQVPNNVTAVLREGAILTCLVVSTMRYNLTWQRNGRDVRLQEPLRMRVMSNLSLEVKAVQFTDAGKYNCVASNKDGSTTASVFLTVQEPPRIVISPKDQTFVEGSEVSIRCSATGYPKPTVVWTHNEMFIIGSNRYRLTPEGTLIIRQAIPKDAGVYGCLASNSAGTEKQTSILTYIEGPTVTIFQSEILVALGDTTVMECKTTGIPHPQVKWFKGDLELRASAFLIIDTHRGLLKIQETQELDAGDYTCVATNDAGRASGKITLDVGSPPVFIQEPSDESVDIGSNITLPCYVQGYPEPKVKWRRLNGASLFSRPLAVSFISQLRTGALSINNLWVNDEGSYVCEAENQFGRIQSQPATITVTGLVAPLIGISPATANVIEGQQLTLPCVLLAGNPIPDRKWIKNSMVLVSNPYINVRSDGSLHLERVRLQDGGDYTCMASNVAGTNNKTTTVNVYVLPIVQHGQQIFSTIEGIPVTLPCKASGVPKPSITWSKKGEVIFPSNEKFSAGSDGSLYVVSPEGEETGEYVCTATNAAGYATRKVQLTVYVKPRVSRPGDQQGHGPVEISVITGDDVTLPCEVKSLPPPIITWAKETQLISPFSLRHTFLLSGSMKISETQVSDSGMYFCVATNIAGNVTQSVKLSVHVPPKIQRGPQIMKVQAGHRVDIPCSAQGNPPPAITWFRGSSAVPIGSGQPTHSLGGALSISNVQLSNAGIYRCIASNAAGSDTSEITIQVQEPPTMDDLDPQYNNPFQERVVNQRIAFPCPVKGTPKPVIKWLHNGRELTGREPGISILENDMLLIIASITPSDNGEYICVATNEAGRTERKYNLEVHVPPEIRDQERVTNTSVVVNHPISLFCEVFGNPFPVISWYKEDIQVVESNTLHQILHNGKILKLLKATVDDAGQYSCKAINVAGSSEKLFNLYILVPPSIIGADTPSEIAVILNQETSLECRAKGFPFPGIHWFKDSMPLFLGDPNVELLEKGQVLHIKSARMVDKGHYQCSATNAAGKQIKEVKLIIHVPPSIKGGNITTEVSALLNNLINLDCETKGIPVPTITWYKEGRRIISSPQALYVDRGQFLQIPHAQVSDSAKYTCHVTNAAGAAEKTYEVDVYVPPVIEGDAETAQSRQVVAGNSLTLECKAAGNPSPLLTWLKDGVPVKASDNLRVVSGGKKLEILNAVEADRGQYLCVATSIAGEQEIKYGVEILVPPFVEGGDEFLDYIVVLHSPLELDCSATGTPLPTITWLKGGQPIEEGTGHKILLSGQKFLISRAQVSDTGHYKCVAVNVAGEHEREFVVTVHVPPTIKSAGTSERAVVVHKAVTLQCIANGIPSPSITWLKDGQPVNTARGNTRLESSGRVLQVAEALLEDAGRYTCVAINAAGEAQQHIRLRVHEPPSLEDAGKMLNETVVVNNPIHLECRALGNPLPAITWYKDSHSLTSAASVTFLNKGQVLEIEGAQISDTGIYKCVAVNIAGTAELSYSLQVHVPPSISDSSDTVTAVVNNLVRMECEARGIPAPILTWLKDGSPVSSFSDGLQILSGGRVLVLTSAQISDTGKYTCVAVNAAGESQRDIDLRVYVPPNIMGEEQNVSVLISQAAELLCQSNAVPLPMLMWLKDGRPLLNKPGLSISEDGSVLKIEGAQVQDTGRYTCEATNVAGKTKKNYNVNIWVPPSIYGSDDTSQLTVIEGSLISLICESTGIPPPSLTWKKSGSPLVADQSGRVRILSGGRQLQISVAEMSDAASYICIASNVAGSAKKEYSLQVYTRPVILDSGSYPSEVVAAQGSEISLECKAQGIPEPAVTWMKDGRPLVSGRDVAVLHDGHFLLLRNIQVSDTGHYVCVAANVAGLYDRKYDLNVHVPPDIAGDLQLPENISTVEKNPISLVCEASGIPLPSVMWLKNGWPVTSNTSVQILSGGRTLRLTHTTVSDEGHYTCVVTNAAGEARKDFYLSVLVPPGIVDENKQEDMKVKEKNSVTLTCEVIGNPVPQITWIKDGQPLMEDKDHRFLSSGRFLQITNAQVSDTGRYTCVASNTAGDKSKSYFLNVLVSPTIVGADSHGSAEEVTVILNSPTSLVCEAYSYPPATITWLKDGSLLESNRNIHILPGGRILQILSAQKHSAARYTCIATNEAGETMKHYEVQVYIPPTINRGDVPGMDLSPKEMKIKINHSLTLECEAHAVPAAAISWYKDGQPLKPDDRVIIQASGHTLQITEAQVSDTGRYTCLASNIAGEDEVEFDINIQVPPSFQKPYRGWESGNMVDTGRGGENKDVIINNPLSLYCETDAVPPPVLTWYKDGYPLNSSDKVLILPGGRVFQIPRARAEDAGRYMCAAVNEAGEDSIHYNVHVLLPPSIRGADGDLPEEVNVLGNKVAVMDCVTSGSPSPSITWEKDGHLLAEDNKHSFLSNGRRLQILNSQVTDTGRYVCVVENIAGRAKKYFNLNVHVPPSVVGANPENLTVVVNNLISLTCEVTGFPPPDLSWLKNGKPVSLNTNTFIVPGARTLQIPQAKLSDDGEYTCIARNHAGESQKKSFLTVLVPPGIKDHSGTSVTVFNVRVGTPVMLECKASAIPPPVITWYKNRRMISESANVEILADGQTLQIKGAEVSDTGQYVCKAINIAGRDDKNFHLNVYVPPNIEGPEEELVIETISNPVAFICDATGIPPPTLVWLKNGKPLENSNSLDVHIFSGGSRLQIAHSQLLDSGTYTCIASNVEGKAQKRFVLSVQVPPSIVGSEMPREVGVLLGEGIQLVCNATGVPMPVVQWLKDGKTVASDNLERIRVAPDGSTLNIFRALTSDTGKYTCVATNPAGEEDQIFNLSVYVPPTITNNKSEPEDLAALLESSINIGCAATGMPSPQINWLKNGLPLSVSSRIRLLSAGQILRLVRVQISDAGVYTCVASSRAGVDNKHYNLQIFVPPSLDNARGTEEVTVAKGSSASLKCFTDGAPPPAMSWFKNGHPLSLGAHQNLNNQGMVLHFVEAEIGDVGKYTCVAANKAGDVSKHFSLKVLEPPQINGSGQPEELSVIVNNPLELLCISTGIPIPKISWMKDGRPLLQNDNIHVIREGLRITSAQVKDAGRYTCLAFSPAGDDDKEYLVRVHVPPNIAGTSGVQDLTVLQNRQIILECKSDAVPPPIISWLKNGELLEGTPRIRILSNGRYMQINNADLGDTANYTCVASNIAGKMTREFMLAVHVAPTIRSSPQTTVVHLNSSVVLECTAEGVPTPRIAWRKDGNVFNGNNTRYSILEDGSLQIHSAHVTDTGRYLCMATNAAGTERKQIDLQVLVPPTIASGHTNITVTVNVQTTLPCEATGIPRPAVSWKKNGHLLSLDQNQNTYRLLSSGSLVIISPTVDDTAVYECSVSNDAGEDQRAVELTVQVPPSIADEATDLLVTKLSPVVISCTASGVPVPSVHWTKNGVKLLPRGDGYRILPSGAVEIPAVQLAHAGQYTCVARNAAGSAHRHTTLHVQERPVIQIQPGMLDVIVNNSILLPCEAVGTPRPIITWQKEGINIMTTGNSYMALPNGSLWITESTVEDAGTYTCVAQNLAGTALGKIKLKVQVPPVIKSHLKEYVVPVDQSVTLQCEAEGNPGPEISWHKDGQQVAESMRRRILSTGALQIVFVQPGDTGHYTCIAANVAGSSSSSMELVVQTPPKIHNTEAHYTVTEDSRAVLACMADGIPTPIINWKKDNTLLTETVGKYKTVPGGDLILDNVVPEDSGTYTCTAMNAAGEDTHAVTLVVHVLPAFTELPGDVTLTKGEQLRLACRASGIPVPKITWTFNNNVIPAQHDDVSGHSELVIERVSKDDSGTYACTAENAVGSIRAIGFVYVKEPPVFRGNYHPSRIEPLGGNAMLNCEVRGDPPPTIQWSKEGVGVQTSKRIQQLNNGSLAIYGTVNEDAGDYKCVATNDAGVVERSLTLTLQSPPVITIEPAGTTVEAGATVMLNCQASGEPPPAIRWSRQGHPFVSDDRMTVLSNGSLHIIAAQKEDTSEYECVARNQMGSVLVRVPLTVQVRGGFSDWLEWQPCSVTCGQGVQKRARWCNNPLPANGGRPCEGPDTDVRSCHNKPCPVDGEWSSWLPWGPCSESCGKGTQTRLRLCSSPSPSHGGSHCRGPDVQRQVCSKRRCPVDGKWAPWGSWSACTVSCGGGSSQRTRQCSDPAPQFGGHRCEGNNIQVDFCNSDPCPIHGSWGPWGSWGTCSRSCNGGQVRRYRGCDSPRPSSGGRACAGADMQIQRCGTGLCPVNGNWGPWQTWSQCSASCGGGEQTRTRLCSNPAPLYNGHPCPGDSSQISRCNSQACPGGPSRALGSIIGNINDIEFGIASLNATVTDSPNSESRVIHAKITSIPRSLGPALRKLVSILSPVYWTTAKEVGEAMNGFTLTDAIFKRETQVEFATGEVLRMTHIARGLDSDGALLLDVVVNGHVLQLQPLANVNMKDYTEDYIQTGPGQLYAYSTRLFAVDGVSVPYMWNHTITYDHTKGKMPFLVETLHASSITTEYNPLEETLAFKIHASISKGDHNNQCPAGFELNSSGPYCTDEDECAVRNPCSHTCHNAVGTYHCSCPKGLTIAADGRMCQDVDECVLGRHACHTDQDCENSAGSYHCVLRCRTGFRRAVDGLSCQDINECQESNSCHQHCINTVGSFHCGCDPGYQLKGRKCIDVNECRQNVCRPDQLCKNTRGGYKCIELCPNGMTKAENGTCIDINECHDRTHQCHYNQICENMQGSYRCVCPRGYRSQGLGRPCVDINECEQVPKPCAFQCTNTPGSFKCICPPGQHLLETTINLNGLTGTPQTCTAPSQSIGTAEYLSPELKGALEKLVLKAMRQEMTDV", "length": 5344, "header": "tr|A0A8V0ZNK5-1|A0A8V0ZNK5_CHICK Computationally mapped isoform of Hemicentin-1 OS=Gallus gallus OX=9031 GN=HMCN1 PE=4 SV=1 CANONICAL=A0A8V0ZHJ2-1" }, "locus": { "chromosome": "8", "start_pos": 10538695, "end_pos": 10351752, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051095.1", "url": "https://www.ensembl.org/id/ENSGALT00010051095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030286.1", "url": "https://www.ensembl.org/id/ENSGALP00010030286.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429823", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429823", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "muscle tendon junction", "id": "GO:0005927", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005927", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "basement membrane organization", "id": "GO:0071711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071711", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" }, { "name": "axon guidance receptor activity", "id": "GO:0008046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1157, "end_pos": 1159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1368, "end_pos": 1370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1552, "end_pos": 1554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1929, "end_pos": 1931, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2112, "end_pos": 2114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2395, "end_pos": 2397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2430, "end_pos": 2432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2689, "end_pos": 2691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2822, "end_pos": 2824, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2976, "end_pos": 2978, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3272, "end_pos": 3274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3336, "end_pos": 3338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3348, "end_pos": 3350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3533, "end_pos": 3535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3690, "end_pos": 3692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3728, "end_pos": 3730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3757, "end_pos": 3759, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3813, "end_pos": 3815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4003, "end_pos": 4005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4041, "end_pos": 4043, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4402, "end_pos": 4404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4492, "end_pos": 4494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4838, "end_pos": 4840, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4984, "end_pos": 4986, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5043, "end_pos": 5045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5211, "end_pos": 5213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 808, "end_pos": 810, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ2" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"end_pos": 3759 }, { "start_pos": 3813, "end_pos": 3815 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 4003, "end_pos": 4005 }, { "start_pos": 4041, "end_pos": 4043 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 4402, "end_pos": 4404 }, { "start_pos": 4492, "end_pos": 4494 }, { "start_pos": 4838, "end_pos": 4840 }, { "start_pos": 4984, "end_pos": 4986 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 5043, "end_pos": 5045 }, { "start_pos": 5211, "end_pos": 5213 }, { "start_pos": 527, "end_pos": 529 }, { "start_pos": 549, "end_pos": 551 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 808, "end_pos": 810 }, { "start_pos": 970, "end_pos": 972 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGE7-1", "uniprot_ac": "A0A8V0ZGE7", "uniprot_id": "A0A8V0ZGE7_CHICK", "mass": { "chemical_mass": 38605.0, "monoisotopic_mass": 38605.0 }, "refseq": { "ac": "XP_015144219", "name": "calcium homeostasis modulator protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144219" }, "gene_names": [ { "name": "CALHM1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE7" } ] }, { "name": "CALHM1", "type": "synonym", "evidence": [ { "id": "XP_015144219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144219" } ] } ], "protein_names": [ { "name": "Calcium homeostasis modulator 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE7/entry#names_and_taxonomy" } ] }, { "name": "calcium homeostasis modulator protein 1", "type": "synonym", "evidence": [ { "id": "XP_015144219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144219" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015144219.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144219" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CALHM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE7", "locus": { "chromosome": "6", "start_pos": 24430981, "end_pos": 24434022, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021128", "url": "https://www.ensembl.org/id/ENSGALG00010021128" } ] } } ], "crossref": [ { "id": "A0A8V0ZGE7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGE7", "database": "AlphaFoldDB", "categories": [] }, { "id": "428977", "url": "https://www.ncbi.nlm.nih.gov/gene/428977", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "8GMQ", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8GMQ&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "IPR029569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428977", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428977", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WHRCKPP", "url": "https://omabrowser.org/oma/group/WHRCKPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAQ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZAQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGE7", "url": "https://www.orthodb.org/?gene=A0A8V0ZGE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00008gmq", "url": "https://www.rcsb.org/structure/pdb_00008gmq", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8GMQ", "url": "https://www.rcsb.org/structure/8GMQ", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF14798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015144219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144219", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKFRMVFQFLQSNQESFMSGICGIMALASAQLYSAFDFNCPCLPRYNLAYGLGVLLVPPLILFLLGFVLNNNVSMLAEEWRRPQGQRQKDAAVLRYMFCSMVQRAMIAPAVWVSVTLLDGKCITCAFCTSLPVEALGNASHRGLPQGEVKRVLARIPCKEIYDGQELIANEVAVRYLRCISQALGWCFVLLMTTLAFLVRSLRPCFTQAVFLKSRYWSHYIDIERKLFDETCAEHAKSFAKVCIQQFFQGMSKDLTATHCHPPRKAPTDAGEASEKLLGITDWDTMNIALKSWHRCKPPLHLHPDAPHSSNGWAGEWQPHTQPHTQPPAPRREAVVYYSGV", "length": 342, "header": "tr|A0A8V0ZGE7-1|A0A8V0ZGE7_CHICK Isoform 1 of Calcium homeostasis modulator 1 OS=Gallus gallus OX=9031 GN=CALHM1 PE=1 SV=1 CANONICAL=A0A8V0ZGE7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE7/entry#A0A8V0ZAQ4-1", "sequence": { "sequence": "MDKFRMVFQFLQSNQESFMSGICGIMALASAQLYSAFDFNCPCLPRYNLAYGLGVLLVPPLILFLLGFVLNNNVSMLAEEWRRPQGQRQKDAAVLRYMFCSMVQRAMIAPAVWVSVTLLDGKCITCAFCTSLPVEALGNASHRGLPQGEVKRVLARIPCKEIYDGQELIANEVAVRYLRCISQALGWCFVLLMTTLAFLVRSLRPCFTQAVFLKSRYWSHYIDIERKLFDETCAEHAKSFAKVCIQQFFQGMSKDLTATHCHPPRKAPTDAGEASEKLLGITDWDTMNIALKSWHRCKPPLHLHPDAPHSSNGWPPAPRREAVVYYSGV", "length": 329, "header": "tr|A0A8V0ZAQ4-1|A0A8V0ZGE7_CHICK Computationally mapped isoform of Calcium homeostasis modulator 1 OS=Gallus gallus OX=9031 GN=CALHM1 PE=1 SV=1 CANONICAL=A0A8V0ZGE7-1" }, "locus": { "chromosome": "6", "start_pos": 24433823, "end_pos": 24431985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051160.1", "url": "https://www.ensembl.org/id/ENSGALT00010051160.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030351.1", "url": "https://www.ensembl.org/id/ENSGALP00010030351.1" } ] } }, { "isoform_ac": "A0A8V0ZGE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE7/entry#A0A8V0ZGE7-1", "sequence": { "sequence": "MDKFRMVFQFLQSNQESFMSGICGIMALASAQLYSAFDFNCPCLPRYNLAYGLGVLLVPPLILFLLGFVLNNNVSMLAEEWRRPQGQRQKDAAVLRYMFCSMVQRAMIAPAVWVSVTLLDGKCITCAFCTSLPVEALGNASHRGLPQGEVKRVLARIPCKEIYDGQELIANEVAVRYLRCISQALGWCFVLLMTTLAFLVRSLRPCFTQAVFLKSRYWSHYIDIERKLFDETCAEHAKSFAKVCIQQFFQGMSKDLTATHCHPPRKAPTDAGEASEKLLGITDWDTMNIALKSWHRCKPPLHLHPDAPHSSNGWAGEWQPHTQPHTQPPAPRREAVVYYSGV", "length": 342, "header": "tr|A0A8V0ZGE7-1|A0A8V0ZGE7_CHICK Isoform 1 of Calcium homeostasis modulator 1 OS=Gallus gallus OX=9031 GN=CALHM1 PE=1 SV=1 CANONICAL=A0A8V0ZGE7-1" }, "locus": { "chromosome": "6", "start_pos": 24433823, "end_pos": 24431985, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051162.1", "url": "https://www.ensembl.org/id/ENSGALT00010051162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030353.1", "url": "https://www.ensembl.org/id/ENSGALP00010030353.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red.", "journal": "Nat. Commun.", "date": "2023", "authors": "Syrj\u00e4nen Johanna L, Epstein Max, G\u00f3mez Ricardo, Furukawa Hiro", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE7" } ], "reference": [ { "type": "PubMed", "id": "37380652", "url": "https://glygen.org/publication/PubMed/37380652" } ] } ], "pathway": [ { "id": "gga:428977", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428977", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z291-1", "protein_name": "Calcium homeostasis modulator protein 1", "gene_name": "Calhm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDKFRMIFQFLQSNQESFMNGICGIMALASAQMYSAFDFNCPCLPGYNVVYSLGILLTPPLVLFLLGLVMNNNISMLAEEWKRPAGRRAKDPAVLRYMFCSMAQRALIAPVVWVAVTLLDGKCFLCAFCTAVPVATLGNGSLVPGLPAPELARLLARVPCPEIYDGNWLLAREVAVRYLRCISQALGWSFVLLTTLLAFVVRSVRPCFTQVAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVCIQQFFEAMNHDLELGHTHGVLATATATATATEAVQSPSDRTEEEREKLRGITDQGTMNRLLTSWHKCKPPLRLGQEAPLMSNGWAGGEPRPPRKEVATYFSKV", "length": 348 }, "evidence": [ { "id": "A0A8V0ZGE7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGE7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4AE44-1", "protein_name": "Calcium homeostasis modulator 1", "gene_name": "Calhm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKFRMIFQFLQSNQESFMNGICGIMALASAQMYSAFDFNCPCLPGYNVVYSMGILLTPPLVLFLLGLVMNNNISMLAEEWKRPLGRRAKDPAVLRYMFCSMAQRALIAPVVWVAVTLLDGKCFLCAFCTAVPVATLGNGSLVPGLPAPELARLLARVPCPEIYDGNWLLAREVAVRYLRCISQALGWSFVLLTTLLAFVVRSVRPCFTQVAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVCIQQFFEAMNHDLELGHTHGVLATASARTTATEAIQSPSDRTEEEREKLRGITDQGSMNRLLTSWHKCKPPLRLGQEAPLMSNGWAGSEPRPPRKEVATYFSKV", "length": 348 }, "evidence": [ { "id": "A0A8V0ZGE7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGE7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S840-1", "protein_name": "Calcium homeostasis modulator 1", "gene_name": "CALHM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDKFRMIFQFLQSNQESFMNGICGIMALASAQMYSAFDFNCPCLPGYNAAYSAGILLAPPLVLFLLGLVMNNNVSMLAEEWKRPPGRRAKDPAVLRYMFCSMAQRALIAPVVWVAVTLLDGKCFLCAFCTAVPVTVLGNGSLVPGLSPPELSRLLARVPCPEIYDGDWLLAREVAVRYLRCISQALGWSFVLLTTLLAFVVRSVRPCFTQAAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVCIQQFFEAMNHDLELGHGHGVLAAAPAGSPAAPATDRAEEEREKLRGITDQGTMNRLLTSWHKCKPPLRLGQKEPLVGNGWAGVGPRPSRKEVATYFSKV", "length": 344 }, "evidence": [ { "id": "A0A8V0ZGE7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGE7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3X6M4-1", "protein_name": "Calcium homeostasis modulator 1", "gene_name": "CALHM1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDKFRMIFQFLQSNQESFMNGICGIMALASAQMYSAFDFNCPCLPGYNAAYSAGILLAPPLVLFLLGLVMNNNVSMLAEEWKRPQGHRAKDPAVLRYMFCSMAQRALIAPVVWVAVTLLDGKCFLCAFCTAVPVSLLGNGSLVPGLPPPELARLLARVPCPEIYEGDWLLAREVAVRYLRCISQALGWSFVLLTTLLAFVVRSVRPCFTQAAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVCIQQFFEAMNHDLELGHAHGALAAGPTGSAAPAATEGVDEEREKLHGITDQGTMNRLLTSWHECKPPLRLGQEEPLVGNGWAGGGPRPSRKEVATYFSKV", "length": 344 }, "evidence": [ { "id": "A0A8V0ZGE7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGE7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IU99-1", "protein_name": "Calcium homeostasis modulator protein 1", "gene_name": "CALHM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMDKFRMIFQFLQSNQESFMNGICGIMALASAQMYSAFDFNCPCLPGYNAAYSAGILLAPPLVLFLLGLVMNNNVSMLAEEWKRPLGRRAKDPAVLRYMFCSMAQRALIAPVVWVAVTLLDGKCFLCAFCTAVPVSALGNGSLAPGLPAPELARLLARVPCPEIYDGDWLLAREVAVRYLRCISQALGWSFVLLTTLLAFVVRSVRPCFTQAAFLKSKYWSHYIDIERKLFDETCTEHAKAFAKVCIQQFFEAMNHDLELGHTHGTLATAPASAAAPTTPDGAEEEREKLRGITDQGTMNRLLTSWHKCKPPLRLGQEEPPLMGNGWAGGGPRPPRKEVATYFSKV", "length": 346 }, "evidence": [ { "id": "A0A8V0ZGE7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGE7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": 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"header": "tr|A0A8V0ZNS5-1|A0A8V0ZNS5_CHICK Computationally mapped isoform of Beta-microseminoprotein OS=Gallus gallus OX=9031 GN=LOC100858647 PE=1 SV=1 CANONICAL=A0A8V0ZHU1-1" }, "locus": { "chromosome": "6", "start_pos": 18591902, "end_pos": 18589262, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051166.1", "url": "https://www.ensembl.org/id/ENSGALT00010051166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030357.1", "url": "https://www.ensembl.org/id/ENSGALP00010030357.1" } ] } }, { "isoform_ac": "A0A8V0ZNT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU1/entry#A0A8V0ZNT0-1", "sequence": { "sequence": "MKPMERRSGHHEFLPHLQITWTSLYNSTESTCRDLLETWSSLEAAHYTMKIFLAFLLAMGIIVTQGDAFCFSKLFKPGEAEKGCMLDGVLYPFGEIPRTENCFRCSCSKNEMHCCSLYHTPVNYDKETCKVIFNKKNCDYEVVQKHPSKPCSGYARVG", "length": 158, "header": "tr|A0A8V0ZNT0-1|A0A8V0ZNT0_CHICK Computationally mapped isoform of Beta-microseminoprotein OS=Gallus gallus OX=9031 GN=LOC100858647 PE=1 SV=1 CANONICAL=A0A8V0ZHU1-1" }, "locus": { "chromosome": "6", "start_pos": 18591902, "end_pos": 18587120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051171.1", "url": "https://www.ensembl.org/id/ENSGALT00010051171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030362.1", "url": "https://www.ensembl.org/id/ENSGALP00010030362.1" } ] } }, { "isoform_ac": "A0A8V0ZNT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU1/entry#A0A8V0ZNT6-1", "sequence": { "sequence": "MKRPACLKSSYSTESTCRDLLETWSSLEAAHYTMKIFLAFLLAMGIIVTQGDAFCFSKLFKPGEAEKGCMLDGVLYPFGEIPRTENCFRCSCSKNEMHCCSLYHTPVNYDKETCKVIFNKKNCDYEVVQKHPSKPCSGYARVG", "length": 143, "header": "tr|A0A8V0ZNT6-1|A0A8V0ZNT6_CHICK Computationally mapped isoform of Beta-microseminoprotein OS=Gallus gallus OX=9031 GN=LOC100858647 PE=1 SV=1 CANONICAL=A0A8V0ZHU1-1" }, "locus": { "chromosome": "6", "start_pos": 18591902, "end_pos": 18583524, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051176.1", "url": "https://www.ensembl.org/id/ENSGALT00010051176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030367.1", "url": "https://www.ensembl.org/id/ENSGALP00010030367.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZI01-1", "uniprot_ac": "A0A8V0ZI01", "uniprot_id": "A0A8V0ZI01_CHICK", "mass": { "chemical_mass": 90164.0, "monoisotopic_mass": 90164.0 }, "refseq": { "ac": "XP_040503438", "name": "AP-5 complex subunit zeta-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503438" }, "gene_names": [ { "name": "AP5Z1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01" } ] }, { "name": "AP5Z1", "type": "synonym", "evidence": [ { "id": "XP_040503438", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503438" } ] } ], "protein_names": [ { "name": "AP-5 complex subunit zeta-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040503438", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503438" } ] }, { "name": "Adaptor related protein complex 5 subunit zeta 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040503438", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503438" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AP5Z1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01", "locus": { "chromosome": "14", "start_pos": 4021828, "end_pos": 4012065, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021146", "url": "https://www.ensembl.org/id/ENSGALG00010021146" } ] } } ], "crossref": [ { "id": "A0A8V0ZI01", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZI01", "database": "AlphaFoldDB", "categories": [] }, { "id": "416478", "url": "https://www.ncbi.nlm.nih.gov/gene/416478", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416478", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416478", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LMLAYEF", "url": "https://omabrowser.org/oma/group/LMLAYEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAV2", "url": "https://www.orthodb.org/?gene=A0A8V0ZAV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI01", "url": "https://www.orthodb.org/?gene=A0A8V0ZI01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46488", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46488", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46488:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46488:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25154", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25154", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040503438", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503438", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTAAAESLLKQAREVQEDELSRFAARVAAQLQGPEPGPEAADCLQRLHLVLAASKSPRQLDAQLVELLQAVLCSPKCPQQIQLLCAAILREMAPCDGLRLSCERIHDTKLLSLVSSVLLAQGEEKAEVSAVGQRIVKALEGRLPEGQSSRYLLPVLSNVISLSPEALTEEQTNVVSKKMADWLRYASTQQGVAQPSGGFFSNPRTRQPGPVTEVDGAIATDFFTVLSLGQHYTEDQWLNMQTFSMLRKWLLCYGDKKMNTPNSGDKSQTDRSVVSVVSTSSTSSRLLPPKERLREKAFEYCQRLIEQSNRQALKKADGDLQKACLIEAVAIMDIICKQDSSYVYRAASFLKILHGRISGDATYARALLPIAQFFLNHGEMAAVDSDAIYKHLFTDIPAQLFHNSSLAFEFVLFCRDNSQLLTETSSVFRQSFPNLFKFLAWNSPPLIAEFVDILPFLLDAGTAIEIFHLLLDLPCLTAALDVQMRSSSLPSSERAACDPAVKPAACLEAFRSPLYRSAFQYLLRVESVSEDFQERLIPLRQLLGSLASSPRVVQCADTVPVLLELFFSVVSEFADASLINQLVVLVLQRSDQLYEIPAFKDDVHRVLSSQLVMLCKLHPALIVELSKELLEFSGTVSNIQNKEPIFTHVVWAIGEYMSVSYDKRCTVEQINRFFETLEAVLFEVTQVRPQISVPNYAPRAITVLMAALTKLAARSQDLIPRVSLFLSKMRTFVQSPAVTSVYCEEDREEILTRATELMNLLKMPSVAQFVFTPSVDVARTRFQKEVNDTLPSALRIVTRLLEPAPGFVPG", "length": 811, "header": "tr|A0A8V0ZI01-1|A0A8V0ZI01_CHICK Isoform 1 of Adaptor related protein complex 5 subunit zeta 1 OS=Gallus gallus OX=9031 GN=AP5Z1 PE=4 SV=1 CANONICAL=A0A8V0ZI01-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01/entry#A0A8V0ZAV2-1", "sequence": { "sequence": "MIIKLDAQLVELLQAVLCSPKCPQQIQLLCAAILREMAPCDGLRLSCERIHDTKLLSLVSSVLLAQGEEKAEVSAVGQRIVKALEGRLPEGQSSRYLLPVLSNVISLSPEALTEEQTNVVSKKMADWLRYASTQQGVAQPSGGFFSNPRTRQPGPVTEVDGAIATDFFTVLSLGQHYTEDQWLNMQTFSMLRKWLLCYGDKKMNTPNSGDKSQTDRSVVSVVSTSSTSSRLLPPKERLREKAFEYCQRLIEQSNRQALKKADGDLQKACLIEAVAIMDIICKQDSSYVYRAASFLKILHGRISGDATYARALLPIAQFFLNHGEMAAVDSDAIYKHLFTDIPAQLFHNSSLAFEFVLFCRDNSQLLTETSSVFRQSFPNLFKFLAWNSPPLIAEFVDILPFLLDAGTAIEIFHLLLDLPCLTAALDVQMRSSSLPSSERAACDPAVKPAACLEAFRSPLYRSAFQYLLRVESVSEDFQERLIPLRQLLGSLASSPRVVQCADTVPVLLELFFSVVSEFADASLINQLVVLVLQRSDQLYEIPAFKDDVHRVLSSQLVMLCKLHPALIVELSKELLEFSGTVSNIQNKEPIFTHVVWAIGEYMSVSYDKRCTVEQINRFFETLEAVLFEVTQVRPQISVPNYAPRAITVLMAALTKLAARSQDLIPRVSLFLSKMRTFVQSPAVTSVYCEEDREEILTRATELMNLLKMPSVAQFVFTPSVDVARTRFQKEVNDTLPSALRIVTRLLEPAPGFVPG", "length": 755, "header": "tr|A0A8V0ZAV2-1|A0A8V0ZI01_CHICK Computationally mapped isoform of Adaptor related protein complex 5 subunit zeta 1 OS=Gallus gallus OX=9031 GN=AP5Z1 PE=4 SV=1 CANONICAL=A0A8V0ZI01-1" }, "locus": { "chromosome": "14", "start_pos": 4021373, "end_pos": 4012646, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051207.1", "url": "https://www.ensembl.org/id/ENSGALT00010051207.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030398.1", "url": "https://www.ensembl.org/id/ENSGALP00010030398.1" } ] } }, { "isoform_ac": "A0A8V0ZI01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01/entry#A0A8V0ZI01-1", "sequence": { "sequence": "MGTAAAESLLKQAREVQEDELSRFAARVAAQLQGPEPGPEAADCLQRLHLVLAASKSPRQLDAQLVELLQAVLCSPKCPQQIQLLCAAILREMAPCDGLRLSCERIHDTKLLSLVSSVLLAQGEEKAEVSAVGQRIVKALEGRLPEGQSSRYLLPVLSNVISLSPEALTEEQTNVVSKKMADWLRYASTQQGVAQPSGGFFSNPRTRQPGPVTEVDGAIATDFFTVLSLGQHYTEDQWLNMQTFSMLRKWLLCYGDKKMNTPNSGDKSQTDRSVVSVVSTSSTSSRLLPPKERLREKAFEYCQRLIEQSNRQALKKADGDLQKACLIEAVAIMDIICKQDSSYVYRAASFLKILHGRISGDATYARALLPIAQFFLNHGEMAAVDSDAIYKHLFTDIPAQLFHNSSLAFEFVLFCRDNSQLLTETSSVFRQSFPNLFKFLAWNSPPLIAEFVDILPFLLDAGTAIEIFHLLLDLPCLTAALDVQMRSSSLPSSERAACDPAVKPAACLEAFRSPLYRSAFQYLLRVESVSEDFQERLIPLRQLLGSLASSPRVVQCADTVPVLLELFFSVVSEFADASLINQLVVLVLQRSDQLYEIPAFKDDVHRVLSSQLVMLCKLHPALIVELSKELLEFSGTVSNIQNKEPIFTHVVWAIGEYMSVSYDKRCTVEQINRFFETLEAVLFEVTQVRPQISVPNYAPRAITVLMAALTKLAARSQDLIPRVSLFLSKMRTFVQSPAVTSVYCEEDREEILTRATELMNLLKMPSVAQFVFTPSVDVARTRFQKEVNDTLPSALRIVTRLLEPAPGFVPG", "length": 811, "header": "tr|A0A8V0ZI01-1|A0A8V0ZI01_CHICK Isoform 1 of Adaptor related protein complex 5 subunit zeta 1 OS=Gallus gallus OX=9031 GN=AP5Z1 PE=4 SV=1 CANONICAL=A0A8V0ZI01-1" }, "locus": { "chromosome": "14", "start_pos": 4021373, "end_pos": 4012163, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051226.1", "url": "https://www.ensembl.org/id/ENSGALT00010051226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030417.1", "url": "https://www.ensembl.org/id/ENSGALP00010030417.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416478", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416478", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYJ5-1", "protein_name": "Adaptor related protein complex 5 subunit zeta 1", "gene_name": "Ap5z1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSAGAESLLHQAREIQDEELQRFCSRVTKLLQEAPGPATVDALQRLFLIVSSTKYPRRLEKACVDLLQTTLCLPTSPEQLQVLCAAILREMSPFNDLTLSCDHTQNTRQLSLVASVLLAQGDRNGEIRQVSQRIFKILENRQPEGPSVRPLLPVLSKVIGLAPGILVEDQTNLLSKRLVDWLRYASIQQGLPYSGGFFSTPRTRQPGPITEVDGAVASDFFTVLSTGQHFTEDQWVNMQAFSMLRKWLLHSGPEDPGSPDADDKSELEGSMLSVLSAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKGDSDLQKACLVEAVLVLDVLCRQDPSFLYRTLSCLKPLHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEAIYAQLLGSLPSERFHSPTLAFEVIHFCTHNLALFDPHFLSLLRLSFPNLFKFLAWNSPPLTAEFVVLLPALVDAGTAVEMLHALLDLPCLTAALDLQLRSTQTPSERPLWDVSLRVPSCLEAFQDPQFQGLFRHLLRTKASGSTERLTPLHQVLKPMASCARVAQCVEAIPVLLQAFFSAVTQTADGPLINQLALLLLERSDSLYPVPQYEARVHRVLSSQLLVLCKLKPSLVVELSRELLEFVGSVSSIRSRASMFTCVVWAIGEYLSVTCDKRCTAEQINKFFEALEALLFEVTQSRPSADLPCCPPELVTALMTTLTKLASRSQDLIPRVSLFLSKMRTLAQNPATSSMHSEEDTESIRIRATELLTLLKMPSVAQFVFTPTVGVCQPRYHQDTNVALPLALRTVSRLVEKEAGLLPG", "length": 807 }, "evidence": [ { "id": "A0A8V0ZI01", "url": "https://omabrowser.org/oma/group/A0A8V0ZI01/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2N0C1-1", "protein_name": "AP-5 complex subunit zeta-1 isoform X1", "gene_name": "Ap5z1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFSAGAESLLHQAREIQDEELQRFCTRVTKLLQEPPGPATMDALQRLFLIVSATKYPRRLEKMCVDLFQTTLCLPTSPEQLQVLCAAILREMSPFDDLALSCDHTQNTRQLSLVASVLLAQGNRKGEIRQVSQRIFKILENRQPEGPSVRHLLPALSKVIGLAPGTLMEDQNNLLSKRLVDWLRYASIQQGLPSSAGFFSTPRTRQPGPITEVDGAVASDFFTVLSTGQHFTEDQWLNMQAFSMLRKWLLHSGPEDPGSPDADDKSELEGSTLSVLSAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKADSDLQKACLVEAVLVLDVLCRQDPSFLYRTLSCLKALHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEVIYQHLLSRLPSERFYSPTLAFEVIHFCTHNLALFDPHILSLLRLSFPSLFKFLAWNSPPLTAEFVVLLPALVEAGTTVEMLHALLDLPCLTAALDLQLRSTQTPSERPLWDVSLRIPGCLEAFRDPQFQGLFRHLLRTKASGSMERLTPLHQLLKPMASCARVTQCAEAVPILLQAFFSTVTQLADGALINQLVLLLLDRSDSLYQAPQYEARVHRVLNSQFLALCKLKPSLVVELSRELLEFVGNVSSICSRASMFTCVVWAIGEYLSVTCDKRCTVEQINKFFEALEALLFEVTQSRPSADLPCCPPQVVTALMTTLTKLASRSQDLIPRVSLFLSKLRTLAQNPATSSVHSEEDAEAIRTRATELLTLLKIPSVAQFVFTPTAGVCQPRYHRDANTALPLALRTVSRLVEKEAGLLPG", "length": 807 }, "evidence": [ { "id": "A0A8V0ZI01", "url": "https://omabrowser.org/oma/group/A0A8V0ZI01/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M6YX82-1", "protein_name": "AP-5 complex subunit zeta-1 isoform X1", "gene_name": "ap5z1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYAAATESLIKQAREIKEEELQRFCGRVYKLLHSKDVIGEAVDSLQRLHLIVSATKYARELPSDLLMKLQTLLRSSSCPEQLQFLSSSIIRESFPPSVHSLSSDLSQDSRIFSCVAAVVLAQAGGKEDVMPLFHHLMKSFESRLSDGQIPKHALPILSSMITTYSEILTDDQVNLVSRKLVDWLRYASMQQGASMSSGGFFSAPRTRQPAPLTEVDGVVTGDFFTVLCVGQSYTEDQWMNMYAFSMIKSWLLTYDTEGTTNTESALLKRAQIIQLQHQDDRSEVDSSVMSMVSATSSSSRLLPPKERLREKAFEYCQRLIEQSDRKALKRTDTELQKACIVESVSIMDIICGEDPSYVYRAFPCIKALYGRLNGDFAYARTLLPIAQFYLNHSETAAVDSEAVFCQLFGHCPAEQFNEPMLAFEFVQFCLLNSSVLQDRVANYRQSFPNLLKFLAWNSSGLIAEFVELLPSLVAPDTAIELLHTILDLPCLAAALDLQQRSSCYQASDRTTWDQQGAKVAACLEAFRQPSYRGLFLYILRPEAGTGDTIDRLKELHQILADMAECPRVVQCAQIVPVLLHVYFNTVTEKADEKMMNQLLLVLLERCSLLYNIKTFHVEVQRAFSTHLQALCKHHPPLIVDQSREILEFAGSPTNIYSKEDFYTHVVWVIGEYLSVSYDPRCRVELITSFFECLEAVLFEITQVRQSASPPSFSPRLITVLMTTLAKLATRSQDLIPRASLFLSKMRTFARSAPVTACYSEEDTEEIITRAHELINLLKLPNVAQFVLAPSAGADGPRWHRDTNASLPQAMRTVSGLLHKHSSFLPA", "length": 826 }, "evidence": [ { "id": "A0A8V0ZI01", "url": "https://omabrowser.org/oma/group/A0A8V0ZI01/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9TCS9-1", "protein_name": "Adaptor related protein complex 5 subunit zeta 1", "gene_name": "AP5Z1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRHAARPGSRRRCGHCFASRPCLERAARPQGGGGGGMLATGTESLLRQAREVGAEELGRFCARVSALLQAEDWGPDALDALRRLFLIVAATKYSRRLEPTCVALLQTTLCSPRCPERLQLLCAAVLREMAPSDSLSLSCDHAQSSRQLGLVASVLLAQGDPQQVRTVGQCVIKVLESRQPEGPSLTYLLPVVSKVTSLAPDALPEEQTKALSKRLGEWLRYASVQQGAAHASGGFFSTPRARQPGPVTEVDGTVATDFFTVLSTGQRFTEDQRLNVQAFSMLRAWLLQGGPARPGAADADDRSELEGSTVSVLSAASAASHLLPPAEWLREKALEYCQRLLEQSGRRALRKADSDLQKACLVEAVLVLDVLCRQDPSFLYRALPCVRALRTRLCGDTACVRALLPIAQFFLHHGEAAAVDADAVCQHLFTRIPSEHFHSPMLAFEFVQFCRDHLVLFGSNLDLLRTSFPNLFKFLAWSSPALTSGFVALLPVLVDAGTAVEMLHLLLDLPSLTAALDLQLRASQAASERPLWDVSVRAPGCLEALRDPQAQGLFQHLLRAKASGTVERLTPLHQLLQPLASCARVLQCAQAVPTLLRAFFAAVTQFASGALASQLALLLLERSDSLFQVEGYEADVHRVLSSQFPALCKLHPPLVVERAKELLEFVGSLGGPRSTGHMLTSVVWAVGEYLSVSWDRRCSAEQISRFFEALEALLFEVTQSRPSAALPKCPPQVITVLMTTLTKLASRSQDLIPRVSLLLSKMRTLAQSPAVGPVHGEDDLGAVRTRATELLNLLKMPSVAQFVLTPSVEVSQPRYHRDCNTALPLALDMVSRLLEREAGLLPGTRPPQHLPLEAVPGRSRALCSSPE", "length": 867 }, "evidence": [ { "id": "A0A8V0ZI01", "url": "https://omabrowser.org/oma/group/A0A8V0ZI01/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RI49-1", "protein_name": "Adaptor related protein complex 5 subunit zeta 1", "gene_name": "AP5Z1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTAGAESLLRQAREIRDEELGRLCSRVCALLGREDWGPDALDALRRLFLIVSATKHGRRLEQPCVELLQAALCSPTCPEQLQLLCAAVLREVSPSRSLSLTCDRVQNTQQLGLVASVLLAQGDRRQVGSVGQCALRVLESRQPEGPGLRHLLPVVSKVTNLAPDALHEEQTNTLNRRLGDWLRHASVQQGIAHSSGGFFSTPRARQPGPVTEVDGAVATDFFTVLSTGQHFTEDQWLNVQAFSMLRAWLLHGGPGGSSTPDADDRSELEGSTLSVLSAASTASHLLPPQERLREKAFEYCQRLIEQSNRRALRKADSELQKACLVEAVLVLDVLCRQDPSFLYRTLSCLRALHARLCGDPTCVRALLPVAQFFLHHGEAAAVDAEAVYQHLCTRIPAEHFHSPLLALEFVQFCRASLPLFGRHLGVLRSSFPNLFKFLAWSSPPLTAEFVALLPSLVDAGTAVEMLDLLLDLPCLTAALDLQLRSSQAASEKPLWDVSVRAAGCLEAFRDPQYQALFQHLLRAKASGTTERLVPLHQLLQPLAGCARVAQCAEAVPILLQAFFAAVTQFADGTLTSQLALLLLERSDTLYEVPGYQARVHKVLSSQFLALCTRRPSLVVEQAKELLEFVGSLGGPHGGGHMLTSVVWAIGEYLSVSWDRRCTVEQINKFFEALEALLFEVTQSRPSAALPACPPQVITVLMTTLTKLASRSQDLIPRVSLFLSKMRTLAQSPAAGSAHGEEDARAVLTRATELLNLLKMPSVAQFVLTPSAEVSEPRYHRDTNTALPLALSTVSRLVERDAGLLPG", "length": 807 }, "evidence": [ { "id": "A0A8V0ZI01", "url": "https://omabrowser.org/oma/group/A0A8V0ZI01/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O43299-1", "protein_name": "AP-5 complex subunit zeta-1", "gene_name": "AP5Z1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSAGAESLLHQAREIQDEELKKFCSRICKLLQAEDLGPDTLDSLQRLFLIISATKYSRRLEKTCVDLLQATLGLPACPEQLQVLCAAILREMSPSDSLSLAWDHTQNSRQLSLVASVLLAQGDRNEEVRAVGQGVLRALESRQPEGPSLRHLLPVMAKVVVLSPGTLQEDQATLLSKRLVDWLRYASLQQGLPHSGGFFSTPRARQPGPVTEVDGAVATDFFTVLSSGHRFTDDQWLNVQAFSMLRAWLLHSGPEGPGTLDTDDRSEQEGSTLSVISATSSAGRLLPPRERLREVAFEYCQRLIEQSNRRALRKGDSDLQKACLVEAVLVLDVLCRQDPSFLYRSLSCLKALHGRVRGDPASVRVLLPLAHFFLSHGEAAAVDSEAVYQHLFTRIPVEQFHSPMLAFEFIQFCRDNLHLFSGHLSTLRLSFPNLFKFLAWNSPPLTSEFVALLPALVDAGTALEMLHALLDLPCLTAVLDLQLRSAPAASERPLWDTSLRAPSCLEAFRDPQFQGLFQYLLRPKASGATERLAPLHQLLQPMAGCARVAQCAQAVPTLLQAFFSAVTQVADGSLINQLALLLLGRSDSLYPAPGYAAGVHSVLSSQFLALCTLKPSLVVELARDLLEFLGSVNGLCSRASLVTSVVWAIGEYLSVTYDRRCTVEQINKFFEALEALLFEVTQCRPSAALPRCPPQVVTVLMTTLTKLASRSQDLIPRASLLLSKMRTLAHSPATSSTHSEEGAEAIRTRATELLTLLKMPSVAQFVLTPSTEVCSPRYHRDANTALPLALRTVSRLVEREAGLMPG", "length": 807 }, "evidence": [ { "id": "A0A8V0ZI01", "url": "https://omabrowser.org/oma/group/A0A8V0ZI01/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3U829-1", "protein_name": "AP-5 complex subunit zeta-1", "gene_name": "Ap5z1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSAGAESLLHQAREIQDEELRRFCSRVTKLLQEAPGPATVDALQRLFLIVSATKYPRRLEKMCVDLLQTTLCLPASPEQLQVLCAAILREMSPFNDLALSCDHTPNTRQLSLVASVLLAQGDRKGEIRCVSQRIFKILENRQPEGPSVRPLLPILSKVIGLAPGILMEDQTNLLSKRLVDWLRYASIQQGLPYSGGFFSTPRTRQPGPITEVDGAVASDFFTVLSTGQHFTEDQWVNMQAFSMLRKWLLHSGPEDPCSPDADDKSELEGSTLSVLSAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKGDSDLQKACLVEAVSVLDVLCRQDPSFLYRTLSCLKALHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEAVYGQLLRGLPSERFHSPTLAFEVIHFCTHNLALFDSHFLSLLRLSFPSLFKFLAWNSPPLTAEFVVLLPALVDAGTAVEMLHALLDLPCLTAALDLQLRSTQTPSERLLWDISLRVPSCLEAFQDPQFQGLFRHLLRTKASGSTERLTPLHQVLKPMASCARVTQCAEAVPVLLQAFFSAVTQTADGALINQLALLLLERSDSLYPVPQYEARVHGVLSSQLLVLCKLKPSLVVELSRELLEFVGSVSSIHSRASVFTCVVWAIGEYLSVTWDKRCTAEQINKFFEALEALLFEVTQSRPLADLPCCPPEVVTALMTTLTKLASRSQDLIPRVSLFLSKMRTLAQNPATSSVHSEEGAESIRTRASELLTLLKMPSVAQFVFTPPAGVCQPRYHRDTNVALPLALRTVSRLVEKEAGLLPG", "length": 807 }, "evidence": [ { "id": "A0A8V0ZI01", "url": "https://omabrowser.org/oma/group/A0A8V0ZI01/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B09-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQTNVSGAVNIEELLNKIENVFGKNQKSLSINSTFIEKFTTLLLDPNTPYKIKLFTLSTLSKFSKNEHQILYKNFKTFDPKTLPLILSLLLSTGTDSQIYISSIPFLVQTISSQDPITRSASMPSLAISARYHSNSLTNLHIKPIETQLIQFLSHASLISDQKQSSIGFFSKIGNTSATPVTELDGSVSIEFFTVLNNSTNYTEDQTFNIYSFSILYTWLINLYKINKQQSLTNTDQQIEQLDQQIEQQLELIEKQQDQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHRTLNQSFQNTIVSYCLRLIDQSKLKPIDGSGNNNSNLNGGNSGNSNSSGGGSMIYNKPIQQQSATAIALGIDESGGDDLSVMALLESIRILDYLCLLDSNLIAKIFPTVQKAYQLHLPSSKNTNATSGHILLALLQFFVNHSHTLVYDPEPLFKVYFQTYLPRTYMNSFVSFETINFCLKNKKTLLKNSNVFNLYFPPIFKCLAWFPNSLSGEFSELLPSFISPNSFIEVFHLLLDLPLLTLSMESVLVEQRKYASMGIEHNDVGVDTAWSEYRVLYNYLLRNESGVNINFWSTTTLPLLQQFCKKNPVTPRSIGSCELVPLLLDIYFEVLLEYGSLNTFVTLLPVIFERMEQIFPYEPYQKRIRENLMSHLLSIFKKHSTLIQSEKELILSVISEARMTYKDIVTLSLSFIIGEYCSPYVCPTITSDVYSDYHEALELITYEKINTIKMESLSNSSQSSLQQSSLIMKQQQQQQQKQQQHQQEQSSSSNNNNNDIKNIENNENDNDIEKLNNDKKNNDNENDQNQNFINNYNLNYNLNINILNNINNFNLNNIIDNDDFEKLQEQYNINIMLNLISSLTKIASRWPDATSRVVLCLMKIIGYQQYFDPQVIQRANESISLLKYPSFAAALYSCQQPQNDSFHSTISSTTIGQTIQDCNSSLSFLLNDTLNYKSKNTIHPFILK", "length": 975 }, "evidence": [ { "id": "A0A8V0ZI01", "url": "https://omabrowser.org/oma/group/A0A8V0ZI01/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "AP-5 adaptor complex", "id": "GO:0044599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044599", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 788, "end_pos": 790, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01" }, { "id": "PF14764", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14764" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-5 complex subunit zeta-1 ARM repeats", "eco_id": "ECO_0000259", "start_pos": 321, "end_pos": 438, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01" }, { "id": "PF25154", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25154" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-5 complex subunit zeta-1 C-terminal TPR", "eco_id": "ECO_0000259", "start_pos": 450, "end_pos": 801, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZI01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI01" }, { "id": "PF25153", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25153" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-5 complex subunit zeta-1 N-terminal TPR", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 280, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 404, "end_pos": 406 }, { "start_pos": 788, "end_pos": 790 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZI21-1", "uniprot_ac": "A0A8V0ZI21", "uniprot_id": "A0A8V0ZI21_CHICK", "mass": { "chemical_mass": 18246.0, "monoisotopic_mass": 18246.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "T-cell receptor alpha chain constant domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI21/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI21" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI21", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZI21", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZI21", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCDSGYGSNNLIFGSGTRLSVGPYITPSPSVYRLTSEDNKDLEMCLITDYSPEKLDLSSVDSKTETVVEVATSENKHEASYLSTYWAKKDEMQCGAKHEGFGILKGDDPEAGASTVCITGMSLLFKTDENLNMLTFSQLGLKIIFMKAVIFNVLITMLMWKKNQ", "length": 165, "header": "tr|A0A8V0ZI21-1|A0A8V0ZI21_CHICK Isoform 1 of T-cell receptor alpha chain constant domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZI21-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI21/entry#A0A8V0ZAY3-1", "sequence": { "sequence": "MLCDSNYGYQLTFGSGTRLIVQPHITPSPSVYRLTSEDNKDLEMCLITDYSPEKLDLSSVDSKTETVVEVATSENKHEASYLSTYWAKKDEMQCGAKHEGFGILKGDDPEAGASTVCITGMSLLFKTDENLNMLTFSQLGLKIIFMKAVIFNVLITMLMWKKNQ", "length": 164, "header": "tr|A0A8V0ZAY3-1|A0A8V0ZI21_CHICK Computationally mapped isoform of T-cell receptor alpha chain constant domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZI21-1" }, "locus": { "chromosome": "27", "start_pos": 142034, "end_pos": 121725, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051237.1", "url": "https://www.ensembl.org/id/ENSGALT00010051237.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030428.1", "url": "https://www.ensembl.org/id/ENSGALP00010030428.1" } ] } }, { "isoform_ac": "A0A8V0ZI21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI21/entry#A0A8V0ZI21-1", "sequence": { "sequence": "MLCDSGYGSNNLIFGSGTRLSVGPYITPSPSVYRLTSEDNKDLEMCLITDYSPEKLDLSSVDSKTETVVEVATSENKHEASYLSTYWAKKDEMQCGAKHEGFGILKGDDPEAGASTVCITGMSLLFKTDENLNMLTFSQLGLKIIFMKAVIFNVLITMLMWKKNQ", "length": 165, "header": "tr|A0A8V0ZI21-1|A0A8V0ZI21_CHICK Isoform 1 of T-cell receptor alpha chain constant domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZI21-1" }, "locus": { "chromosome": "27", "start_pos": 176008, "end_pos": 121725, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051241.1", "url": "https://www.ensembl.org/id/ENSGALT00010051241.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030432.1", "url": "https://www.ensembl.org/id/ENSGALP00010030432.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 27, "start_aa": "Thr", "end_pos": 27, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr27", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 27 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZI61-1", "uniprot_ac": "A0A8V0ZI61", "uniprot_id": "A0A8V0ZI61_CHICK", "mass": { "chemical_mass": 202441.0, "monoisotopic_mass": 202441.0 }, "refseq": { "ac": "XP_015130825", "name": "uncharacterized protein KIAA1671 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130825" }, "gene_names": [ { "name": "KIAA1671", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61" } ] }, { "name": "KIAA1671", "type": "synonym", "evidence": [ { "id": "XP_015130825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130825" } ] } ], "protein_names": [ { "name": "KIAA1671", "type": "synonym", "evidence": [ { "id": "A0A8V0ZI61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein KIAA1671 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015130825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130825" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015130825.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015130825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130825" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA1671", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61", "locus": { "chromosome": "15", "start_pos": 6999890, "end_pos": 6956789, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021167", "url": "https://www.ensembl.org/id/ENSGALG00010021167" } ] } } ], "crossref": [ { "id": "768701", "url": "https://www.ncbi.nlm.nih.gov/gene/768701", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CREGDNS", "url": "https://omabrowser.org/oma/group/CREGDNS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB19", "url": "https://www.orthodb.org/?gene=A0A8V0ZB19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB25", "url": "https://www.orthodb.org/?gene=A0A8V0ZB25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB28", "url": "https://www.orthodb.org/?gene=A0A8V0ZB28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGR3", "url": "https://www.orthodb.org/?gene=A0A8V0ZGR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI44", "url": "https://www.orthodb.org/?gene=A0A8V0ZI44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI57", "url": "https://www.orthodb.org/?gene=A0A8V0ZI57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI61", "url": "https://www.orthodb.org/?gene=A0A8V0ZI61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP38", "url": "https://www.orthodb.org/?gene=A0A8V0ZP38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP50", "url": "https://www.orthodb.org/?gene=A0A8V0ZP50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22042", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22042", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22042:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22042:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15327", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15327", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015130825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130825", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATRVEINSTLASLTTVPDLNEIRTEDKSQRVYVSVLSDVSSKTKEPSASLMLEEKNKFGSTLRSATMPSLGSRPRLFPKPFSKDTPSDTFANVKPPITAFRSSSLIRKPSEETTSAKVSGGNVPPLVDHKAIGNESKAGSEVVTNMTYYSGHNTNTVILFETAGTEQSKVSLAQGKRAADDRRVLSTMQTKEPQCNVKQEKPSQPSPETSRSPEGSLHRQISLSSSLRPVSWNSLKAGEKKDATEDHPAEKNNTDANNMNSKVDFSLDVQQKPKPRPVSAAFLESLRDQKHRTVEASEEKSPTEKSWVRKPRPLSMDLTAKFELKDLATSKKTCSSHESKESVSVTSFTDVGSHGQSETGPKTEEMEFNKGSSSKTNLKCSSQEIGILNKGKHTWEAKQKSESEQTETKPSIVTNLHSSERAFESTGESRTNREGKRLDQKETCVFVSCESPAASSEKENSIVRGSVKKHISLFTSENPNPSGDTETLPSAAERENKCMNIQQRIKELTTESTDAKPGSLRRSLQSRPLSADLTKMFSSPTSSTSEAKPEKAAEVRNSSGSETQEHQKTTLAHSGDATEAHAAGNPWKSRQVLKITNRTDQTETKGSFPGDSQRFSQQSENPVSFTSSFEKRLKPTNATEKTCIKTVRATMFDHNVQRHNVADDLPATASPLKMSGELEAKPDVVTLGHTRRSWVGEAFPSKSAARDPNDFFSSECTLSERKKDLDKTETDAVLIAEKTPYSTNRSKCSGINEKTSKLHAEIKTDRSEDSSTDETGRSNLVKCSSEKRSFRQGGIDYEFGPSFGHEVISTSVKKQQVHSSSVLLSGQLCKSSSSLHPDVKEESRAFALGRSLDSNCKDQAFGLRSKAPENREKIRVIDPEEKVRRTKSSISDLKTSERWRRKTLPHDSVKAEEISWLTPENTKRLSWTDSLQLEENSLKKRNIKERMEGNEANQTAPGSSDEHLKSQSSAFEPKATYFAVTYQIPSIKKEKSFVGTASTISSKISSSSEGGAVNLGPDFSGRSKPDKSITSTDCREESREVYIKKDWVKGEDKDNASSKNIASGSFHVSGKDNQKCYEKGLDQSKEKIIDVDAFLLKQERENAAQSDLKGSRGKVSSYHEPRSSLHFAQLHKDGEAVTQKSSESSYGVSGRKAEDAYRPQVLDIDALMAEYKEESVKGSSIQDKVSEEHSLFGRNKSKNKRNVSDRVTSSYTWKEWKGSDHHAVSNKQGECAEEYHRPEKLVPTEKSKEKLDSHGPEADKQKSKDRKLFSPSWENPSCLFPDKFANSPVEFTAKKTFIIDDDQDMNLTSRNQSSQVVVDKVQPVHAIGVDQKLEVNFASRLSIKANDGLLQKKVVTKEQFSEVTLEGDWSKNVARSSVTRDRDDASKVTCANDSSNVKSKTKDWKSYTSGLGSAPPDLRRSYSEKSRPGKDGLALLHEARGRKDLYRSRQSFPPESVDNGWKTKVSSQSESIFHEDKKAPRKEWTKQSSEKTDGREFSFVSTQRRSHSFFYKDRRAESITDQLKQCFTRQPPEAKDTDTLVQEPDSQYGTWSEQRRSGDSFVPESPSSENDAISTRKQPPNSQPSSLSSQTEPTSLADRCDFSKDQRSTSLDRSSTDIDSTDGTELPPPGDAYPDGKTTDFSFIDQTTILDSSALKNRVQLSKKRRHRAPLSHSLRRSRGLEYENRFSLTEESGSTWMFKDSTEEKKPMQQEDSDEEEKTQRSGRLSSVQAQRLPIFPGMDHSVLKAQLRKRHESESPGEPSSAQPFKSPKPQLGTPGSRILPSSVEKEERSEEKSPQWLKELKSKKRQSHYENQV", "length": 1817, "header": "tr|A0A8V0ZI61-1|A0A8V0ZI61_CHICK Isoform 1 of KIAA1671 OS=Gallus gallus OX=9031 GN=KIAA1671 PE=4 SV=1 CANONICAL=A0A8V0ZI61-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61/entry#A0A8V0ZB19-1", "sequence": { "sequence": "GHLLCVLSASDQLKQCFTRQPPEAKDTDTLVQEPDSQYGTWSEQRRSGDSFVPESPSSENDAISTRKQPPNSQPSSLSSQTEPTSLADRCDFSKDQRSTSLDRSSTDIDSTDGTELPPPGDAYPDGKTTDFSFIDQTTILDSSALKNRVQLSKKRRHRAPLSHSLRRSRGLEYENRFSLTEESGSTWMFKDSTEEKKPMQQEDSDEEEKTQRSGRLSSVQAQRLPIFPGMDHSVLKAQLRKRHESESPGEPSSAQPFKSPKPQLGTPGSRILPSSVEKEERSEEKSPQWLKELKSKKRQSHYENQV", "length": 306, "header": "tr|A0A8V0ZB19-1|A0A8V0ZI61_CHICK Computationally mapped isoform of KIAA1671 OS=Gallus gallus OX=9031 GN=KIAA1671 PE=4 SV=1 CANONICAL=A0A8V0ZI61-1" }, "locus": { "chromosome": "15", "start_pos": 6996803, "end_pos": 6989011, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051275.1", "url": "https://www.ensembl.org/id/ENSGALT00010051275.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030466.1", "url": "https://www.ensembl.org/id/ENSGALP00010030466.1" } ] } }, { "isoform_ac": "A0A8V0ZB25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61/entry#A0A8V0ZB25-1", "sequence": { "sequence": "MAGWGISKLYSNLSHSVTWAQGGFFTGDPRQSHIPMAGVAWGDGPFLALLLSALLLFWHSFLLISFLAALEYCQDQLKQCFTRQPPEAKDTDTLVQEPDSQYGTWSEQRRSGDSFVPESPSSENDAISTRKQPPNSQPSSLSSQTEPTSLADRCDFSKDQRSTSLDRSSTDIDSTDGTELPPPGDAYPDGKTTDFSFIDQTTILDSSALKNRVQLSKKRRHRAPLSHSLRRSRGLEYENRFSLTEESGSTWMFKDSTEEKKPMQQEDSDEEEKTQRSGRLSSVQAQRLPIFPGMDHSVLKAQLRKRHESESPGEPSSAQPFKSPKPQLGTPGSRILPSSVEKEERSEEKSPQWLKELKSKKRQSHYENQV", "length": 370, "header": "tr|A0A8V0ZB25-1|A0A8V0ZI61_CHICK Computationally mapped isoform of KIAA1671 OS=Gallus gallus OX=9031 GN=KIAA1671 PE=4 SV=1 CANONICAL=A0A8V0ZI61-1" }, "locus": { "chromosome": "15", "start_pos": 6996803, "end_pos": 6985861, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051280.1", "url": "https://www.ensembl.org/id/ENSGALT00010051280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030471.1", "url": "https://www.ensembl.org/id/ENSGALP00010030471.1" } ] } }, { "isoform_ac": "A0A8V0ZB28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61/entry#A0A8V0ZB28-1", "sequence": { "sequence": "ANVIDQLKQCFTRQPPEAKDTDTLVQEPDSQYGTWSEQRRSGDSFVPESPSSENDAISTRKQPPNSQPSSLSSQTEPTSLADRCDFSKDQRSTSLDRSSTDIDSTDGTELPPPGDAYPDGKTTDFSFIDQTTILDSSALKNRVQLSKKRRHRAPLSHSLRRSRGLEYENRFSLTEESGSTWMFKDSTEEKKPMQQEDSDEEEKTQRSGRLSSVQAQRLPIFPGMDHSVLKAQLRKRHESESPGEPSSAQPFKSPKPQLGTPGSRILPSSVEKEERSEEKSPQWLKELKSKKRQSHYENQV", "length": 300, "header": "tr|A0A8V0ZB28-1|A0A8V0ZI61_CHICK Computationally mapped isoform of KIAA1671 OS=Gallus gallus OX=9031 GN=KIAA1671 PE=4 SV=1 CANONICAL=A0A8V0ZI61-1" }, "locus": { "chromosome": "15", "start_pos": 6996803, "end_pos": 6984798, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051285.1", "url": "https://www.ensembl.org/id/ENSGALT00010051285.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030476.1", "url": "https://www.ensembl.org/id/ENSGALP00010030476.1" } ] } }, { "isoform_ac": "A0A8V0ZGR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61/entry#A0A8V0ZGR3-1", "sequence": { "sequence": "MDLSHYFCQYCSISLRTLCCSSAFGAEEGSPVYPCMQVELEPLRLLREKAAVPGTAIYGHRAGWGGRQRVLLRGTHCPTAPSSVPAMTFSLWAAFIHWIDQLKQCFTRQPPEAKDTDTLVQEPDSQYGTWSEQRRSGDSFVPESPSSENDAISTRKQPPNSQPSSLSSQTEPTSLADRCDFSKDQRSTSLDRSSTDIDSTDGTELPPPGDAYPDGKTTDFSFIDQTTILDSSALKNRVQLSKKRRHRAPLSHSLRRSRGLEYENRFSLTEESGSTWMFKDSTEEKKPMQQEDSDEEEKTQRSGRLSSVQAQRLPIFPGMDHSVLKAQLRKRHESESPGEPSSAQPFKSPKPQLGTPGSRILPSSVEKEERSEEKSPQWLKELKSKKRQSHYENQV", "length": 395, "header": "tr|A0A8V0ZGR3-1|A0A8V0ZGR3_CHICK Computationally mapped isoform of KIAA1671 OS=Gallus gallus OX=9031 GN=KIAA1671 PE=4 SV=1 CANONICAL=A0A8V0ZI61-1" }, "locus": { "chromosome": "15", "start_pos": 6996803, "end_pos": 6987786, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051277.1", "url": "https://www.ensembl.org/id/ENSGALT00010051277.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030468.1", "url": "https://www.ensembl.org/id/ENSGALP00010030468.1" } ] } }, { "isoform_ac": "A0A8V0ZI44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61/entry#A0A8V0ZI44-1", "sequence": { "sequence": "MDQLKQCFTRQPPEAKDTDTLVQEPDSQYGTWSEQRRSGDSFVPESPSSENDAISTRKQPPNSQPSSLSSQTEPTSLADRCDFSKDQRSTSLDRSSTDIDSTDGTELPPPGDAYPDGKTTDFSFIDQTTILDSSALKNRVQLSKKRRHRAPLSHSLRRSRGLEYENRFSLTEESGSTWMFKDSTEEKKPMQQEDSDEEEKTQRSGRLSSVQAQRLPIFPGMDHSVLKAQLRKRHESESPGEPSSAQPFKSPKPQLGTPGSRILPSSVEKEERSEEKSPQWLKELKSKKRQSHYENQV", "length": 297, "header": "tr|A0A8V0ZI44-1|A0A8V0ZI44_CHICK Computationally mapped isoform of KIAA1671 OS=Gallus gallus OX=9031 GN=KIAA1671 PE=4 SV=1 CANONICAL=A0A8V0ZI61-1" }, "locus": { "chromosome": "15", "start_pos": 6996803, "end_pos": 6987563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051278.1", "url": "https://www.ensembl.org/id/ENSGALT00010051278.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030469.1", "url": "https://www.ensembl.org/id/ENSGALP00010030469.1" } ] } }, { "isoform_ac": "A0A8V0ZI57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61/entry#A0A8V0ZI57-1", "sequence": { "sequence": "MRKGGGRKRGMRMGAQHSTQHMHEAQGWITVLLRTEEWKDQLKQCFTRQPPEAKDTDTLVQEPDSQYGTWSEQRRSGDSFVPESPSSENDAISTRKQPPNSQPSSLSSQTEPTSLADRCDFSKDQRSTSLDRSSTDIDSTDGTELPPPGDAYPDGKTTDFSFIDQTTILDSSALKNRVQLSKKRRHRAPLSHSLRRSRGLEYENRFSLTEESGSTWMFKDSTEEKKPMQQEDSDEEEKTQRSGRLSSVQAQRLPIFPGMDHSVLKAQLRKRHESESPGEPSSAQPFKSPKPQLGTPGSRILPSSVEKEERSEEKSPQWLKELKSKKRQSHYENQV", "length": 335, "header": "tr|A0A8V0ZI57-1|A0A8V0ZI57_CHICK Computationally mapped isoform of KIAA1671 OS=Gallus gallus OX=9031 GN=KIAA1671 PE=4 SV=1 CANONICAL=A0A8V0ZI61-1" }, "locus": { "chromosome": "15", "start_pos": 6996803, "end_pos": 6981934, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051288.1", "url": "https://www.ensembl.org/id/ENSGALT00010051288.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030479.1", "url": "https://www.ensembl.org/id/ENSGALP00010030479.1" } ] } }, { "isoform_ac": "A0A8V0ZI61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61/entry#A0A8V0ZI61-1", "sequence": { "sequence": "MATRVEINSTLASLTTVPDLNEIRTEDKSQRVYVSVLSDVSSKTKEPSASLMLEEKNKFGSTLRSATMPSLGSRPRLFPKPFSKDTPSDTFANVKPPITAFRSSSLIRKPSEETTSAKVSGGNVPPLVDHKAIGNESKAGSEVVTNMTYYSGHNTNTVILFETAGTEQSKVSLAQGKRAADDRRVLSTMQTKEPQCNVKQEKPSQPSPETSRSPEGSLHRQISLSSSLRPVSWNSLKAGEKKDATEDHPAEKNNTDANNMNSKVDFSLDVQQKPKPRPVSAAFLESLRDQKHRTVEASEEKSPTEKSWVRKPRPLSMDLTAKFELKDLATSKKTCSSHESKESVSVTSFTDVGSHGQSETGPKTEEMEFNKGSSSKTNLKCSSQEIGILNKGKHTWEAKQKSESEQTETKPSIVTNLHSSERAFESTGESRTNREGKRLDQKETCVFVSCESPAASSEKENSIVRGSVKKHISLFTSENPNPSGDTETLPSAAERENKCMNIQQRIKELTTESTDAKPGSLRRSLQSRPLSADLTKMFSSPTSSTSEAKPEKAAEVRNSSGSETQEHQKTTLAHSGDATEAHAAGNPWKSRQVLKITNRTDQTETKGSFPGDSQRFSQQSENPVSFTSSFEKRLKPTNATEKTCIKTVRATMFDHNVQRHNVADDLPATASPLKMSGELEAKPDVVTLGHTRRSWVGEAFPSKSAARDPNDFFSSECTLSERKKDLDKTETDAVLIAEKTPYSTNRSKCSGINEKTSKLHAEIKTDRSEDSSTDETGRSNLVKCSSEKRSFRQGGIDYEFGPSFGHEVISTSVKKQQVHSSSVLLSGQLCKSSSSLHPDVKEESRAFALGRSLDSNCKDQAFGLRSKAPENREKIRVIDPEEKVRRTKSSISDLKTSERWRRKTLPHDSVKAEEISWLTPENTKRLSWTDSLQLEENSLKKRNIKERMEGNEANQTAPGSSDEHLKSQSSAFEPKATYFAVTYQIPSIKKEKSFVGTASTISSKISSSSEGGAVNLGPDFSGRSKPDKSITSTDCREESREVYIKKDWVKGEDKDNASSKNIASGSFHVSGKDNQKCYEKGLDQSKEKIIDVDAFLLKQERENAAQSDLKGSRGKVSSYHEPRSSLHFAQLHKDGEAVTQKSSESSYGVSGRKAEDAYRPQVLDIDALMAEYKEESVKGSSIQDKVSEEHSLFGRNKSKNKRNVSDRVTSSYTWKEWKGSDHHAVSNKQGECAEEYHRPEKLVPTEKSKEKLDSHGPEADKQKSKDRKLFSPSWENPSCLFPDKFANSPVEFTAKKTFIIDDDQDMNLTSRNQSSQVVVDKVQPVHAIGVDQKLEVNFASRLSIKANDGLLQKKVVTKEQFSEVTLEGDWSKNVARSSVTRDRDDASKVTCANDSSNVKSKTKDWKSYTSGLGSAPPDLRRSYSEKSRPGKDGLALLHEARGRKDLYRSRQSFPPESVDNGWKTKVSSQSESIFHEDKKAPRKEWTKQSSEKTDGREFSFVSTQRRSHSFFYKDRRAESITDQLKQCFTRQPPEAKDTDTLVQEPDSQYGTWSEQRRSGDSFVPESPSSENDAISTRKQPPNSQPSSLSSQTEPTSLADRCDFSKDQRSTSLDRSSTDIDSTDGTELPPPGDAYPDGKTTDFSFIDQTTILDSSALKNRVQLSKKRRHRAPLSHSLRRSRGLEYENRFSLTEESGSTWMFKDSTEEKKPMQQEDSDEEEKTQRSGRLSSVQAQRLPIFPGMDHSVLKAQLRKRHESESPGEPSSAQPFKSPKPQLGTPGSRILPSSVEKEERSEEKSPQWLKELKSKKRQSHYENQV", "length": 1817, "header": "tr|A0A8V0ZI61-1|A0A8V0ZI61_CHICK Isoform 1 of KIAA1671 OS=Gallus gallus OX=9031 GN=KIAA1671 PE=4 SV=1 CANONICAL=A0A8V0ZI61-1" }, "locus": { "chromosome": "15", "start_pos": 6996803, "end_pos": 6965189, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051294.1", "url": "https://www.ensembl.org/id/ENSGALT00010051294.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030484.1", "url": "https://www.ensembl.org/id/ENSGALP00010030484.1" } ] } }, { "isoform_ac": "A0A8V0ZP38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61/entry#A0A8V0ZP38-1", "sequence": { "sequence": "MDYLGDKLTVAQTHMTQWMGTVRRSLQEALNLVTAAVAHERAAGPRAPLKRTSSFRHFASRSRESFRRFSVRSQQRFSSLRKRQSSAEPPDLVSRAPRDDLGVDDPRAIWALCGVIWSAFGVRNEPRAVAGKGVCSQLAGARVEIFARALAARRVCWCKDQLKQCFTRQPPEAKDTDTLVQEPDSQYGTWSEQRRSGDSFVPESPSSENDAISTRKQPPNSQPSSLSSQTEPTSLADRCDFSKDQRSTSLDRSSTDIDSTDGTELPPPGDAYPDGKTTDFSFIDQTTILDSSALKNRVQLSKKRRHRAPLSHSLRRSRGLEYENRFSLTEESGSTWMFKDSTEEKKPMQQEDSDEEEKTQRSGRLSSVQAQRLPIFPGMDHSVLKAQLRKRHESESPGEPSSAQPFKSPKPQLGTPGSRILPSSVEKEERSEEKSPQWLKELKSKKRQSHYENQV", "length": 455, "header": "tr|A0A8V0ZP38-1|A0A8V0ZP38_CHICK Computationally mapped isoform of KIAA1671 OS=Gallus gallus OX=9031 GN=KIAA1671 PE=4 SV=1 CANONICAL=A0A8V0ZI61-1" }, "locus": { "chromosome": "15", "start_pos": 6996803, "end_pos": 6985027, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051281.1", "url": "https://www.ensembl.org/id/ENSGALT00010051281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030472.1", "url": "https://www.ensembl.org/id/ENSGALP00010030472.1" } ] } }, { "isoform_ac": "A0A8V0ZP50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61/entry#A0A8V0ZP50-1", "sequence": { "sequence": "MRVQIASLLRRAAFKCVGVLLAAAGGGERGQPGPKEDGSALALHRGRMEYYYCPRLLKFLQYLWDQLKQCFTRQPPEAKDTDTLVQEPDSQYGTWSEQRRSGDSFVPESPSSENDAISTRKQPPNSQPSSLSSQTEPTSLADRCDFSKDQRSTSLDRSSTDIDSTDGTELPPPGDAYPDGKTTDFSFIDQTTILDSSALKNRVQLSKKRRHRAPLSHSLRRSRGLEYENRFSLTEESGSTWMFKDSTEEKKPMQQEDSDEEEKTQRSGRLSSVQAQRLPIFPGMDHSVLKAQLRKRHESESPGEPSSAQPFKSPKPQLGTPGSRILPSSVEKEERSEEKSPQWLKELKSKKRQSHYENQV", "length": 360, "header": "tr|A0A8V0ZP50-1|A0A8V0ZP50_CHICK Computationally mapped isoform of KIAA1671 OS=Gallus gallus OX=9031 GN=KIAA1671 PE=4 SV=1 CANONICAL=A0A8V0ZI61-1" }, "locus": { "chromosome": "15", "start_pos": 6996803, "end_pos": 6975936, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051291.1", "url": "https://www.ensembl.org/id/ENSGALT00010051291.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030482.1", "url": "https://www.ensembl.org/id/ENSGALP00010030482.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1777, "start_aa": "Thr", "end_pos": 1777, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1777", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1056, "end_pos": 1058, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1196, "end_pos": 1198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1203, "end_pos": 1205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1307, "end_pos": 1309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1312, "end_pos": 1314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1393, "end_pos": 1395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 745, "end_pos": 747, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" }, { "start_pos": 954, "end_pos": 956, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZI61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI61" }, { "id": "SM01319", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01319" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tankyrase 1-binding protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 1639, "end_pos": 1808, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1777 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1056, "end_pos": 1058 }, { "start_pos": 1196, "end_pos": 1198 }, { "start_pos": 1203, "end_pos": 1205 }, { "start_pos": 1307, "end_pos": 1309 }, { "start_pos": 1312, "end_pos": 1314 }, { "start_pos": 135, "end_pos": 137 }, { "start_pos": 1393, "end_pos": 1395 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 558, "end_pos": 560 }, { "start_pos": 598, "end_pos": 600 }, { "start_pos": 638, "end_pos": 640 }, { "start_pos": 745, "end_pos": 747 }, { "start_pos": 8, "end_pos": 10 }, { "start_pos": 954, "end_pos": 956 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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{ "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGT4-1", "uniprot_ac": "A0A8V0ZGT4", "uniprot_id": "A0A8V0ZGT4_CHICK", "mass": { "chemical_mass": 70084.0, "monoisotopic_mass": 70084.0 }, "refseq": {}, "gene_names": [ { "name": "NEURL1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase NEURL1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#names_and_taxonomy" } ] }, { "name": "Neuralized-like protein 1A", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase NEURL1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. 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}, { "id": "PTHR12429:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12429:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZB44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1U7", "url": "https://www.uniprot.org/uniprotkb/F1P1U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1U7-1", "url": "https://www.uniprot.org/uniprotkb/F1P1U7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHGPRCGAPGDASSCCTVAAVNAASSRRGRIKRRGKKKKTHTEVFCQEAAVSSAECEFGQGGAECCSSQGTLLLGSGCESPRRGRGSRALAVPAAAGDASLADSIGGSFPASSHRCHHKQKHCLPIPQCGALSITPLLFHPHTKGSQIVMDTTQKAVKRQASFCNAITFSNRPIVIYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDSAAMLFFSGVRTAEPLWALIDVYGLTRGVQLLDSEIIPPDCLRPRSFTAIRRPSLRRETEDTRLSVSLCDLNLQEESFHVTATTCPIPQNSLNSQHSHLLPSQLESDLRFHHLRGAHVKILDDQTVARLEHAREERTLVFTSRPLRINETIFVKINKSNAARTGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCRVLVPLQSGDILGFMVNSDGELHLSHNGASTGMQVCVDSSQPLWMFFGLHGAVMQIRVLGSTVLAERLGPSTPSSPTSTPNSPTVLCSGVSDPILSTCGSGPLCSSISGTAPNSPVSLPESPISPSVPGPWGDECTICYENMVDTVIYSCGHMCLCYSCGLKLKKMANACCPICRRAIKDIIKTYRST", "length": 646, "header": "tr|A0A8V0ZGT4-1|A0A8V0ZGT4_CHICK Isoform 1 of E3 ubiquitin-protein ligase NEURL1 OS=Gallus gallus OX=9031 GN=NEURL1 PE=4 SV=1 CANONICAL=A0A8V0ZGT4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#A0A8V0ZB44-1", "sequence": { "sequence": "MGGRGSNGSQSVLVCKSLQQVGRICDSIGGSFPASSHRCHHKQKHCLPIPQCGALSITPLLFHPHTKGSQIVMDTTQKAVKRQASFCNAITFSNRPIVIYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDSAAMLFFSGVRTAEPLWALIDVYGLTRGVQLLDSEIIPPDCLRPRSFTAIRRPSLRRETEDTRLSVSLCDLNLQEESFHVTATTCPIPQNSLNSQHSHLLPSQLESDLRFHHLRGAHVKILDDQTVARLEHAREERTLVFTSRPLRINETIFVKINKSNAARTGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCRVLVPLQSGDILGFMVNSDGELHLSHNGASTGMQVCVDSSQPLWMFFGLHGAVMQIRVLGSTVLAERLGPSTPSSPTSTPNSPTVLCSGVSDPILSTCGSGPLCSSISGTAPNSPVSLPESPISPSVPGPWGDECTICYENMVDTVIYSCGHMCLCYSCGLKLKKMANACCPICRRAIKDIIKTYRST", "length": 569, "header": "tr|A0A8V0ZB44-1|A0A8V0ZGT4_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase NEURL1 OS=Gallus gallus OX=9031 GN=NEURL1 PE=4 SV=1 CANONICAL=A0A8V0ZGT4-1" }, "locus": { "chromosome": "6", "start_pos": 24584037, "end_pos": 24503880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051300.1", "url": "https://www.ensembl.org/id/ENSGALT00010051300.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030491.1", "url": "https://www.ensembl.org/id/ENSGALP00010030491.1" } ] } }, { "isoform_ac": "A0A8V0ZGT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#A0A8V0ZGT4-1", "sequence": { "sequence": "MHGPRCGAPGDASSCCTVAAVNAASSRRGRIKRRGKKKKTHTEVFCQEAAVSSAECEFGQGGAECCSSQGTLLLGSGCESPRRGRGSRALAVPAAAGDASLADSIGGSFPASSHRCHHKQKHCLPIPQCGALSITPLLFHPHTKGSQIVMDTTQKAVKRQASFCNAITFSNRPIVIYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDSAAMLFFSGVRTAEPLWALIDVYGLTRGVQLLDSEIIPPDCLRPRSFTAIRRPSLRRETEDTRLSVSLCDLNLQEESFHVTATTCPIPQNSLNSQHSHLLPSQLESDLRFHHLRGAHVKILDDQTVARLEHAREERTLVFTSRPLRINETIFVKINKSNAARTGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCRVLVPLQSGDILGFMVNSDGELHLSHNGASTGMQVCVDSSQPLWMFFGLHGAVMQIRVLGSTVLAERLGPSTPSSPTSTPNSPTVLCSGVSDPILSTCGSGPLCSSISGTAPNSPVSLPESPISPSVPGPWGDECTICYENMVDTVIYSCGHMCLCYSCGLKLKKMANACCPICRRAIKDIIKTYRST", "length": 646, "header": "tr|A0A8V0ZGT4-1|A0A8V0ZGT4_CHICK Isoform 1 of E3 ubiquitin-protein ligase NEURL1 OS=Gallus gallus OX=9031 GN=NEURL1 PE=4 SV=1 CANONICAL=A0A8V0ZGT4-1" }, "locus": { "chromosome": "6", "start_pos": 24584037, "end_pos": 24509456, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051297.1", "url": "https://www.ensembl.org/id/ENSGALT00010051297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030488.1", "url": "https://www.ensembl.org/id/ENSGALP00010030488.1" } ] } }, { "isoform_ac": "A0A8V0ZI34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#A0A8V0ZI34-1", "sequence": { "sequence": "MVLVDQHSKPESLQLHVTRDSIGGSFPASSHRCHHKQKHCLPIPQCGALSITPLLFHPHTKGSQIVMDTTQKAVKRQASFCNAITFSNRPIVIYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDSAAMLFFSGVRTAEPLWALIDVYGLTRGVQLLDSEIIPPDCLRPRSFTAIRRPSLRRETEDTRLSVSLCDLNLQEESFHVTATTCPIPQNSLNSQHSHLLPSQLESDLRFHHLRGAHVKILDDQTVARLEHAREERTLVFTSRPLRINETIFVKINKSNAARTGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCRVLVPLQSGDILGFMVNSDGELHLSHNGASTGMQVCVDSSQPLWMFFGLHGAVMQIRVLGSTVLAERLGPSTPSSPTSTPNSPTVLCSGVSDPILSTCGSGPLCSSISGTAPNSPVSLPESPISPSVPGPWGDECTICYENMVDTVIYSCGHMCLCYSCGLKLKKMANACCPICRRAIKDIIKTYRST", "length": 563, "header": "tr|A0A8V0ZI34-1|A0A8V0ZI34_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase NEURL1 OS=Gallus gallus OX=9031 GN=NEURL1 PE=4 SV=1 CANONICAL=A0A8V0ZGT4-1" }, "locus": { "chromosome": "6", "start_pos": 24584037, "end_pos": 24529539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051269.1", "url": "https://www.ensembl.org/id/ENSGALT00010051269.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030459.1", "url": "https://www.ensembl.org/id/ENSGALP00010030459.1" } ] } }, { "isoform_ac": "A0A8V0ZI50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#A0A8V0ZI50-1", "sequence": { "sequence": "MGCWGQRERGGERRIPEASAAISGRREVSSFLYSIGGSFPASSHRCHHKQKHCLPIPQCGALSITPLLFHPHTKGSQIVMDTTQKAVKRQASFCNAITFSNRPIVIYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDSAAMLFFSGVRTAEPLWALIDVYGLTRGVQLLDSEIIPPDCLRPRSFTAIRRPSLRRETEDTRLSVSLCDLNLQEESFHVTATTCPIPQNSLNSQHSHLLPSQLESDLRFHHLRGAHVKILDDQTVARLEHAREERTLVFTSRPLRINETIFVKINKSNAARTGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCRVLVPLQSGDILGFMVNSDGELHLSHNGASTGMQVCVDSSQPLWMFFGLHGAVMQIRVLGSTVLAERLGPSTPSSPTSTPNSPTVLCSGVSDPILSTCGSGPLCSSISGTAPNSPVSLPESPISPSVPGPWGDECTICYENMVDTVIYSCGHMCLCYSCGLKLKKMANACCPICRRAIKDIIKTYRST", "length": 576, "header": "tr|A0A8V0ZI50-1|A0A8V0ZI50_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase NEURL1 OS=Gallus gallus OX=9031 GN=NEURL1 PE=4 SV=1 CANONICAL=A0A8V0ZGT4-1" }, "locus": { "chromosome": "6", "start_pos": 24584037, "end_pos": 24510723, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051283.1", "url": "https://www.ensembl.org/id/ENSGALT00010051283.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030474.1", "url": "https://www.ensembl.org/id/ENSGALP00010030474.1" } ] } }, { "isoform_ac": "A0A8V0ZI51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#A0A8V0ZI51-1", "sequence": { "sequence": "MQRGTNAGLNYSVCSAEPWSLPALLDSIGGSFPASSHRCHHKQKHCLPIPQCGALSITPLLFHPHTKGSQIVMDTTQKAVKRQASFCNAITFSNRPIVIYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDSAAMLFFSGVRTAEPLWALIDVYGLTRGVQLLDSEIIPPDCLRPRSFTAIRRPSLRRETEDTRLSVSLCDLNLQEESFHVTATTCPIPQNSLNSQHSHLLPSQLESDLRFHHLRGAHVKILDDQTVARLEHAREERTLVFTSRPLRINETIFVKINKSNAARTGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCRVLVPLQSGDILGFMVNSDGELHLSHNGASTGMQVCVDSSQPLWMFFGLHGAVMQIRVLGSTVLAERLGPSTPSSPTSTPNSPTVLCSGVSDPILSTCGSGPLCSSISGTAPNSPVSLPESPISPSVPGPWGDECTICYENMVDTVIYSCGHMCLCYSCGLKLKKMANACCPICRRAIKDIIKTYRST", "length": 569, "header": "tr|A0A8V0ZI51-1|A0A8V0ZI51_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase NEURL1 OS=Gallus gallus OX=9031 GN=NEURL1 PE=4 SV=1 CANONICAL=A0A8V0ZGT4-1" }, "locus": { "chromosome": "6", "start_pos": 24584037, "end_pos": 24511159, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051274.1", "url": "https://www.ensembl.org/id/ENSGALT00010051274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030465.1", "url": "https://www.ensembl.org/id/ENSGALP00010030465.1" } ] } }, { "isoform_ac": "A0A8V0ZI65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#A0A8V0ZI65-1", "sequence": { "sequence": "MSCSIGTGLSVQTSHQGVDGDSIGGSFPASSHRCHHKQKHCLPIPQCGALSITPLLFHPHTKGSQIVMDTTQKAVKRQASFCNAITFSNRPIVIYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDSAAMLFFSGVRTAEPLWALIDVYGLTRGVQLLDSEIIPPDCLRPRSFTAIRRPSLRRETEDTRLSVSLCDLNLQEESFHVTATTCPIPQNSLNSQHSHLLPSQLESDLRFHHLRGAHVKILDDQTVARLEHAREERTLVFTSRPLRINETIFVKINKSNAARTGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCRVLVPLQSGDILGFMVNSDGELHLSHNGASTGMQVCVDSSQPLWMFFGLHGAVMQIRVLGSTVLAERLGPSTPSSPTSTPNSPTVLCSGVSDPILSTCGSGPLCSSISGTAPNSPVSLPESPISPSVPGPWGDECTICYENMVDTVIYSCGHMCLCYSCGLKLKKMANACCPICRRAIKDIIKTYRST", "length": 564, "header": "tr|A0A8V0ZI65-1|A0A8V0ZI65_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase NEURL1 OS=Gallus gallus OX=9031 GN=NEURL1 PE=4 SV=1 CANONICAL=A0A8V0ZGT4-1" }, "locus": { "chromosome": "6", "start_pos": 24584037, "end_pos": 24510313, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051289.1", "url": "https://www.ensembl.org/id/ENSGALT00010051289.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030480.1", "url": "https://www.ensembl.org/id/ENSGALP00010030480.1" } ] } }, { "isoform_ac": "A0A8V0ZI69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#A0A8V0ZI69-1", "sequence": { "sequence": "MSDSIGGSFPASSHRCHHKQKHCLPIPQCGALSITPLLFHPHTKGSQIVMDTTQKAVKRQASFCNAITFSNRPIVIYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDSAAMLFFSGVRTAEPLWALIDVYGLTRGVQLLDSEIIPPDCLRPRSFTAIRRPSLRRETEDTRLSVSLCDLNLQEESFHVTATTCPIPQNSLNSQHSHLLPSQLESDLRFHHLRGAHVKILDDQTVARLEHAREERTLVFTSRPLRINETIFVKINKSNAARTGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCRVLVPLQSGDILGFMVNSDGELHLSHNGASTGMQVCVDSSQPLWMFFGLHGAVMQIRVLGSTVLAERLGPSTPSSPTSTPNSPTVLCSGVSDPILSTCGSGPLCSSISGTAPNSPVSLPESPISPSVPGPWGDECTICYENMVDTVIYSCGHMCLCYSCGLKLKKMANACCPICRRAIKDIIKTYRST", "length": 546, "header": "tr|A0A8V0ZI69-1|A0A8V0ZI69_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase NEURL1 OS=Gallus gallus OX=9031 GN=NEURL1 PE=4 SV=1 CANONICAL=A0A8V0ZGT4-1" }, "locus": { "chromosome": "6", "start_pos": 24584037, "end_pos": 24510489, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051293.1", "url": "https://www.ensembl.org/id/ENSGALT00010051293.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030485.1", "url": "https://www.ensembl.org/id/ENSGALP00010030485.1" } ] } }, { "isoform_ac": "A0A8V0ZI78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#A0A8V0ZI78-1", "sequence": { "sequence": "MGSRFSRIPALPRGGQGRLHRARHHHLKDSIGGSFPASSHRCHHKQKHCLPIPQCGALSITPLLFHPHTKGSQIVMDTTQKAVKRQASFCNAITFSNRPIVIYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDSAAMLFFSGVRTAEPLWALIDVYGLTRGVQLLDSEIIPPDCLRPRSFTAIRRPSLRRETEDTRLSVSLCDLNLQEESFHVTATTCPIPQNSLNSQHSHLLPSQLESDLRFHHLRGAHVKILDDQTVARLEHAREERTLVFTSRPLRINETIFVKINKSNAARTGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCRVLVPLQSGDILGFMVNSDGELHLSHNGASTGMQVCVDSSQPLWMFFGLHGAVMQIRVLGSTVLAERLGPSTPSSPTSTPNSPTVLCSGVSDPILSTCGSGPLCSSISGTAPNSPVSLPESPISPSVPGPWGDECTICYENMVDTVIYSCGHMCLCYSCGLKLKKMANACCPICRRAIKDIIKTYRST", "length": 572, "header": "tr|A0A8V0ZI78-1|A0A8V0ZI78_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase NEURL1 OS=Gallus gallus OX=9031 GN=NEURL1 PE=4 SV=1 CANONICAL=A0A8V0ZGT4-1" }, "locus": { "chromosome": "6", "start_pos": 24584037, "end_pos": 24452326, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051304.1", "url": "https://www.ensembl.org/id/ENSGALT00010051304.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030495.1", "url": "https://www.ensembl.org/id/ENSGALP00010030495.1" } ] } }, { "isoform_ac": "A0A8V0ZP27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#A0A8V0ZP27-1", "sequence": { "sequence": "MTAVLKALFAKDSIGGSFPASSHRCHHKQKHCLPIPQCGALSITPLLFHPHTKGSQIVMDTTQKAVKRQASFCNAITFSNRPIVIYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDSAAMLFFSGVRTAEPLWALIDVYGLTRGVQLLDSEIIPPDCLRPRSFTAIRRPSLRRETEDTRLSVSLCDLNLQEESFHVTATTCPIPQNSLNSQHSHLLPSQLESDLRFHHLRGAHVKILDDQTVARLEHAREERTLVFTSRPLRINETIFVKINKSNAARTGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCRVLVPLQSGDILGFMVNSDGELHLSHNGASTGMQVCVDSSQPLWMFFGLHGAVMQIRVLGSTVLAERLGPSTPSSPTSTPNSPTVLCSGVSDPILSTCGSGPLCSSISGTAPNSPVSLPESPISPSVPGPWGDECTICYENMVDTVIYSCGHMCLCYSCGLKLKKMANACCPICRRAIKDIIKTYRST", "length": 555, "header": "tr|A0A8V0ZP27-1|A0A8V0ZP27_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase NEURL1 OS=Gallus gallus OX=9031 GN=NEURL1 PE=4 SV=1 CANONICAL=A0A8V0ZGT4-1" }, "locus": { "chromosome": "6", "start_pos": 24584037, "end_pos": 24519682, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051271.1", "url": "https://www.ensembl.org/id/ENSGALT00010051271.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030462.1", "url": "https://www.ensembl.org/id/ENSGALP00010030462.1" } ] } }, { "isoform_ac": "F1P1U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4/entry#F1P1U7-1", "sequence": { "sequence": "MGGQVTRGPLHDSIGGSFPASSHRCHHKQKHCLPIPQCGALSITPLLFHPHTKGSQIVMDTTQKAVKRQASFCNAITFSNRPIVIYEQVRLKITKKQCCWSGALRLGFTSKDPSRINPDTLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRVNDSAAMLFFSGVRTAEPLWALIDVYGLTRGVQLLDSEIIPPDCLRPRSFTAIRRPSLRRETEDTRLSVSLCDLNLQEESFHVTATTCPIPQNSLNSQHSHLLPSQLESDLRFHHLRGAHVKILDDQTVARLEHAREERTLVFTSRPLRINETIFVKINKSNAARTGTLSYGVTSCDPSTLRPSDLPYNPESLVDRKEFWAVCRVLVPLQSGDILGFMVNSDGELHLSHNGASTGMQVCVDSSQPLWMFFGLHGAVMQIRVLGSTVLAERLGPSTPSSPTSTPNSPTVLCSGVSDPILSTCGSGPLCSSISGTAPNSPVSLPESPISPSVPGPWGDECTICYENMVDTVIYSCGHMCLCYSCGLKLKKMANACCPICRRAIKDIIKTYRST", "length": 555, "header": "tr|F1P1U7-1|A0A8V0ZGT4_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase NEURL1 OS=Gallus gallus OX=9031 GN=NEURL1 PE=4 SV=1 CANONICAL=A0A8V0ZGT4-1" }, "locus": { "chromosome": "6", "start_pos": 24584037, "end_pos": 24510952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051279.1", "url": "https://www.ensembl.org/id/ENSGALT00010051279.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030470.1", "url": "https://www.ensembl.org/id/ENSGALP00010030470.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423875", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423875", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "apical dendrite", "id": "GO:0097440", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097440", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 14, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "regulation of signaling", "id": "GO:0023051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023051", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "regulation of cell communication", "id": "GO:0010646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010646", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "positive regulation of synapse maturation", "id": "GO:0090129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090129", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "positive regulation of filopodium assembly", "id": "GO:0051491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "positive regulation of dendritic spine development", "id": "GO:0060999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060999", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "cellular response to amino acid stimulus", "id": "GO:0071230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071230", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "positive regulation of long-term neuronal synaptic plasticity", "id": "GO:0048170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "protein monoubiquitination", "id": "GO:0006513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "regulation of Notch signaling pathway", "id": "GO:0008593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" }, { "name": "translation regulator activity", "id": "GO:0045182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" }, { "id": "PS51065", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51065" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NHR", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 292, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZGT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT4" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 593, "end_pos": 633, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 414, "end_pos": 416 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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"A0A8V0ZGU8-1", "uniprot_ac": "A0A8V0ZGU8", "uniprot_id": "A0A8V0ZGU8_CHICK", "mass": { "chemical_mass": 120057.0, "monoisotopic_mass": 120057.0 }, "refseq": {}, "gene_names": [ { "name": "IPO7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU8" } ] } ], "protein_names": [ { "name": "Importin 7", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IPO7", "url": 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"IPR013713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423046", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423046", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVAKTSW", "url": "https://omabrowser.org/oma/group/WVAKTSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB75", "url": "https://www.orthodb.org/?gene=A0A8V0ZB75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGU8", "url": "https://www.orthodb.org/?gene=A0A8V0ZGU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NBA8", "url": "https://www.orthodb.org/?gene=F1NBA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10997:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10997:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08506", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08506", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZB75", "url": 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"MDPNTIIEALRGTMDPALREAAERQLNEAHKSVNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGEIPPYSIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAVVEKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLIAAMQHFLPVLKDSFIQLLSDPSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVDRDVPAETLQVDEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHAVTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTSCSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSAQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDLEQIPQVLNQVAGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEEDEETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKTIFQTIQNRNPVWYQTLTQGLNEEQRKQLQDYRKSHLQYKLGGRLNFYTCGGMSICPTSLFSLPYLGVYSFSVNKVIE", "length": 1041, "header": "tr|A0A8V0ZGU8-1|A0A8V0ZGU8_CHICK Isoform 1 of Importin 7 OS=Gallus gallus OX=9031 GN=IPO7 PE=1 SV=1 CANONICAL=A0A8V0ZGU8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU8/entry#A0A8V0ZB75-1", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSVNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGEIPPYSIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAVVEKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLIAAMQHFLPVLKDSFIQLLSDPSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVDRDVPAETLQVDEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHAVTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTSCSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSAQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDLEQIPQVLNQVAGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEEDEETEELGSDEDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKTIFQTIQNRNPVWYQTLTQGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFNAPVVPTSFNFGGPAPGMN", "length": 1016, "header": "tr|A0A8V0ZB75-1|A0A8V0ZGU8_CHICK Computationally mapped isoform of Importin 7 OS=Gallus gallus OX=9031 GN=IPO7 PE=1 SV=1 CANONICAL=A0A8V0ZGU8-1" }, "locus": { "chromosome": "5", "start_pos": 9069400, "end_pos": 9038023, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051326.1", "url": "https://www.ensembl.org/id/ENSGALT00010051326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030517.1", "url": "https://www.ensembl.org/id/ENSGALP00010030517.1" } ] } }, { "isoform_ac": "A0A8V0ZGU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU8/entry#A0A8V0ZGU8-1", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSVNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGEIPPYSIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAVVEKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLIAAMQHFLPVLKDSFIQLLSDPSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVDRDVPAETLQVDEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHAVTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTSCSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSAQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDLEQIPQVLNQVAGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEEDEETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKTIFQTIQNRNPVWYQTLTQGLNEEQRKQLQDYRKSHLQYKLGGRLNFYTCGGMSICPTSLFSLPYLGVYSFSVNKVIE", "length": 1041, "header": "tr|A0A8V0ZGU8-1|A0A8V0ZGU8_CHICK Isoform 1 of Importin 7 OS=Gallus gallus OX=9031 GN=IPO7 PE=1 SV=1 CANONICAL=A0A8V0ZGU8-1" }, "locus": { "chromosome": "5", "start_pos": 9069400, "end_pos": 9037560, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051313.1", "url": "https://www.ensembl.org/id/ENSGALT00010051313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030504.1", "url": "https://www.ensembl.org/id/ENSGALP00010030504.1" } ] } }, { "isoform_ac": "F1NBA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU8/entry#F1NBA8-1", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSVNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGEIPPYSIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAVVEKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLIAAMQHFLPVLKDSFIQLLSDPSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVDRDVPAETLQVDEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHAVTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTSCSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSAQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDLEQIPQVLNQVAGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEEDEETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKTIFQTIQNRNPVWYQTLTQGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFNAPVVPTSFNFGGPAPGMN", "length": 1038, "header": "tr|F1NBA8-1|A0A8V0ZGU8_CHICK Computationally mapped isoform of Importin 7 OS=Gallus gallus OX=9031 GN=IPO7 PE=1 SV=3 CANONICAL=A0A8V0ZGU8-1" }, "locus": { "chromosome": "5", "start_pos": 9069400, "end_pos": 9038023, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051323.1", "url": "https://www.ensembl.org/id/ENSGALT00010051323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030514.1", "url": "https://www.ensembl.org/id/ENSGALP00010030514.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423046", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423046", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AE96-1", "protein_name": "Importin 7", "gene_name": "Ipo7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDDAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "A0A8V0ZGU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGE5-1", "protein_name": "Importin 7", "gene_name": "IPO7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDEEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "A0A8V0ZGU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4IRR2-1", "protein_name": "Importin beta-like SAD2", "gene_name": "SAD2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLHSLALILRTAALSPIPDERKVSEQQLNQLEHTPQHLVRLLQIAVDGNCDMAVRQIASIQFKNLIAKNWSPEDCGPAVRQQQIFESDKELVRDNILVYVTQVPTLLRSQLGESLKTIIYADYPEQWPRLLDWVKYNLQNQQIYGALFVLRILSRKYEFKSDEERTPVSRIVEETFPQLLTIFNGLIQIPNPSLEIAELMKLICKIFWSSIYLELPRQLFDLNVFNAWMVLFLSVSERPVPVEGQPMDPELRKSWGWWKVKKWTVHILNRLYSRFGDPKLQSPENKPFAQMFQKNYAGRILEGHLNFLNTIRVGGYLPDRVINLLLQYLSNSISKNSMYKLLLPRLDVLLFEIVFPLMCFNDNDQKLWEEDPHEYVRKGYNIIEDLYSPRTASMDFVNELVRKRGKENLPKFVKFVVEIFLSYEKATVEEKPYRQKDGAMLAVGALCDKLKQTDPYKSQLELMLVQHIFPDFNSPVGHLRAKAAWVAGQYAHINFSDQNNFRKALHSVVSGLRDPDLPVRVDSVFALRSFVEACKDLNEIRPILPQLLDEFFKLMNEVENEDLVFTLETIVDKFGEEMAPFAFGLCQNLAAAFWRCLNTSEANDDSDDMGALAAVGCLRAISTILESVSSLPQLFVEIEPTILPIMQKMLTTDGQEVFEEVLEIASYMTFYSPSISLDIWSLWPLMVEALVDWGIDFFPNILVPMDNFISRGTAHFLTCKEPDYQQSLYNVLSTLMTDRNIEDSEIESAPKLIEVVFQNCKGQVDQWVEPYLRLTVDRLQRAETSYVKSLLIQVVANMLYYNPGLTLGVLHNTGLASKVFDLWFQMLQQKRKSGLPANFKREHDKKVCCLGLTSLLALPGGQFPDEALQRVFRATLDLLVAYKNQLAEAAKETEVDYEEEMNGLQSSDDDYDDDGSDGEMDDTEEGDEAQSVKLQKLAAQAKAFHYDDDDDDDSDDDFSDEDEFQSPIDEVDAFVFFVDAIRVMQASDAQRFQNLNQSLDFTYQAIANGIAQHAELRRVEIEKEKQKKLAAASTPVTAL", "length": 1040 }, "evidence": [ { "id": "A0A8V0ZGU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "G3I7Z8-1", "protein_name": "Importin-7 isoform X1", "gene_name": "Ipo7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "A0A8V0ZGU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O95373-1", "protein_name": "Importin-7", "gene_name": "IPO7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDRETAPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "A0A8V0ZGU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P46970-1", "protein_name": "Nonsense-mediated mRNA decay protein 5", "gene_name": "NMD5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDITELLQCFACTLDHNAAVRTNAETHLKNASKVPGFLGACLDIIAADEVPENIKLSASLYFKNKITYGWSAGARQGSNELLDSHVDPDEKPVVKDMLIKTMVSVSKTSPRCIRVLKSALTVIISEDYPSKKWGNLLPNSLELLANEDITVTYVGLLCLAEIFRTYRWKNNDERQDLEELILNYFPALLNYGANVLFQDGKYMNNEQIGELVKLIIKIYKFVSYHDLPFTLQRSESFTPWACFFVSIIQQPLPQEVLAISDIEVRSKNPWVKCKKWALANLYRLFQRYASTSLTRKFQYDEFKQMYCEEFLTQFLQVVFDQIEKWGTGQLWLSDECLYYILNFVEQCVVQKTTWKLVGPHYNVILQHVIFPLLKPTAETLEAFDNDPQEYINRNMDFWDVGYSPDLAALALLTTCVTKRGKTTLQPTLEFMVSTLQSAVGDYNNIMLDNALQIESCLRIFSSIIDRLITKDSPFASEMEKFILTYVLPFFKSQYGFLQSRVCDICSKLGSMDFKDPVITSTIYEGVMNCLNNSSNSLPVELTAALALQTFISDDQFNMKLSEHVVPTMQKLLSLSNDFESDVISGVMQDFVEQFAEQLQPFGVELMNTLVQQFLKLAIDLHETSNLDPDSFTNVDSIPDESDKQMAALGILSTTISILLSFENSPEILKNLEQSFYPAAEFILKNDIEDFYRECCEFVENSTFLLRDITPISWKILELIGECNRKPDSMVSYYLSDFMLALNNILIYGRNELKKNEFYTKIIFEIYQKAVTAEDNSLDDLRVVFDLSQELVLALDDSLPQQYRERLLADVVGSILTQKNELKTNVVFSVTAFNVVISNMITEPLITLQYLKQQGCLEIFFQTWITDYIPNYKRCYDIKLSVLALLKIILKLESNDYSVLNLENLVPQLGSIVTQLASRLPTALRQLANQRKEFSSSGFEEDTKWDENFLDVGDDDENDDEGDLTEKYLELIKNRADSLDFVDGYDAKETFDDLEEDPLTGSILDTVDVYKVFKESIANLQHVDSNRYQGILRHLTPADQELFMGIMNA", "length": 1048 }, "evidence": [ { "id": "A0A8V0ZGU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q55CX9-1", "protein_name": "Probable importin-7 homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDPIIQTIQLFQHTLHHDANVIKAAEAQLQQIKVTDGYSRILLKILASNEVDISIRQGVSIFLKNMIITKWRGAEDESPITQEDAEFIKENLIDLLVHSHHLVQNQIEAMIEIIANRDFPEKWTSLLPKSIQYINTQDVKLILAGLTSIQLGIKRFRYVTMGDKKKELLYTIVNEIFPLLLQILEFLSQHQTIESALMQKKVIKIFGYAIHFEIPDLLIQPEVFNKWLSQFVRIIQRPITPQENVKHADDCRKNQWWLLKRTTAKLLNLLFRKSATSVRSTDHSSVKALNKLFMPVYSVEVMKVFYEQLSTLEQLYKGVHYERYQQKLIEYFSFAIKYGVTYVAMKPWLSTLIQQVLFPIICFNDRDAELWECDPNEFLRSQFESSMTFATARIEVLNFIIDVVGKRGRANLDMIMGFCIQSLNKYNAATNASEKNPREKDGVLVIISVLSAYLKNISFYKSNLEQMLLLHVFPELSSPHGFLKARACSLFSEFYNIEFTDPVYFSNALKLILGLMSDNDLPVRVKAGTSICNLVRANQGVDELRPILPQLLDKIFSLLSEAESEDLVIAIESIIQRFKHEIAPYAVNLCKNLSEQFLRLLELEESDESGESGFASQECLGVYCTLLRALKDIPDVFNSLEQQIVPILQKLFTSDHMMYLDEALRILTFVTYYPKSISPLVWSLFPQIMNLFDECACDFASSYVNPLDNYISYGTEYFLSNQQYIEMVFNMYKKMVGDINQQPVDAGDCCKIMESLIQRAKGRIDYMIVPVLELACGRLLNTDKNNQKSKEFTVYLLEIIANCIYYNPLISTQYLESKNLVEPIFGLWFNRIKHFQRFYDKKISVLAFSSLLTLNPSPNFVKFGTSLILEKMLQFTKDMLSIEKELDKQEAEREQKIKDGTLKPEEEEFIDENDEEDYFDNHKFEFEFTEIPDNQDCQHDDEGEVFLDDIEKATEYFENGGDLGEDEGDNFDDQNDDDDQDSEEDLFEDEDTPDFETPIDEVDGFEFMINSIQNFFQINPTCIQQISEKQQEKIKKYVASAPARKEKLRLEKEKEEKLKQQQQKK", "length": 1065 }, "evidence": [ { "id": "A0A8V0ZGU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9EPL8-1", "protein_name": "Importin-7", "gene_name": "Ipo7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPNTIIEALRGTMDPALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNMITQYWPDREATPGDIAPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYPSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKDRFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNLKPHIQGIIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEEVTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGILNTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQQVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRTMCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLGLCALIDMEQIPQVLNQVSGQILPAFILLFNGLKRAYACHAEHENDSDDDEDAEDDDETEELGSDEDDIDEDGQEYLEILAKQAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALTHGLNEEQRKQLQDIATLADQRRAAHESKMIEKHGGYKFSAPVVPSSFNFGGPAPGMN", "length": 1038 }, "evidence": [ { "id": "A0A8V0ZGU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VSD6-1", "protein_name": "Moleskin", "gene_name": "msk", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIC2-1", "uniprot_ac": "A0A8V0ZIC2", "uniprot_id": "A0A8V0ZIC2_CHICK", "mass": { "chemical_mass": 317118.0, "monoisotopic_mass": 317118.0 }, "refseq": { "ac": "XP_004945213", "name": "trinucleotide repeat-containing gene 18 protein isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945213" }, "gene_names": [ { "name": "TNRC18", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC2" } ] }, { "name": "TNRC18", "type": "synonym", "evidence": [ { "id": "XP_004945213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945213" } ] } ], "protein_names": [ { "name": "Trinucleotide repeat containing 18", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC2/entry#names_and_taxonomy" } ] }, { "name": "trinucleotide repeat-containing gene 18 protein isoform X3", "type": "synonym", "evidence": [ { "id": "XP_004945213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945213" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945213.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945213" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TNRC18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC2", "locus": { "chromosome": "14", "start_pos": 4094352, "end_pos": 4139400, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021188", "url": "https://www.ensembl.org/id/ENSGALG00010021188" } ] } } ], "crossref": [ { "id": "cd04714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20469", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20469", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416482", "url": "https://www.ncbi.nlm.nih.gov/gene/416482", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048924", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048924", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056841", "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12505:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945213", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMDGRDFGPPPRSAHGPPPPLLSGLPMDGHRLAAGRLPPSAPLAAGLPAALQPGKFLASGIGLHAHPGFSHLPNGLYPSYIPLSHLEPPSTGSPLLAQLGQHSLFESQKDGFYLSSHAAQSALHPQPPLARSAGSHTPSALLREKELGQLHKSSKESLKDPGGKERGCRTELSLPFAKKEGRPKEEPRPRSVVDLTQDSKPEGERKVSVVEKAAKAGERLSPFLAEHVPSRGGGGGEAKSKNPLQSSSLSNCNGGGDPVLKVLGAEQDRCAKDPARHDENVRPSAHAHAERLKRGETLLPSVGALHVSCSCPSPHPSQPGKMAPAATFPPQPVHSSVYTIFPPAKELGREHKVIAPTFVPSVEAYDERSGPIQIASQARDNKAKEKELGKAGVLQSPPERCLADASRALLSQDFSCHGDAKRMEVLREKGSVIRANSMALKRQVASEPFLNRPGLGSPESREFLASKDLLKSSPEAEHRPCERERFQRSSSKEATKVYGTLDSSRQHLDHSQLKPPEQKWKPFEMGNFATTQMAVLAAQHNHVTRAEEEAKKVYLDPSGLPRSSVVGSRGAADVLHPTSHSEGSAMQSLIKYSGSFAKETASRQSCGKKSPFGGLGNMKLDSSQLGTSKVQQLLTQQPAKQLKRDPERPESAKSFGRESIGSQGEVEVRHLPVGIAVAVARQKDNSSSSSGSKLTPSLADRDRSLSLSSIKGHSRSEDDCGDERSRHRDSHLLAGRLERDQEKLLRESKELVDFARIHPSGCATNGLNSNLMVTGGPALAGSGRWSTDPASHLAAHPWLPRTGSPSMWLAGHPYGLGHPSLHQGMTPGFPPAMGGALPSAYQFARDPQSGQLVVIPSEHLPHFAELMDRAPPLWPAMYPPTRSSLQHAHQLQLLSHQQLLRQHELYILQQQAAHAMELQRSAQLVERLKANEQRADMEEKVTKRSLDSAKSGLSSSAPGLVHRKPPVLSPSASTSYSKAVSPPPLSPRASPVSVLKAEVIQKMEEPPSQPAYSYPATPSSHPSSPPPASPPPAPAIPPKEEAPESVEKKDLELEKEAAGPFQALFQEIPPGYPFQSLPPSFGRHYPYLLQPTAAADADGLAPDVPLPAEGSEHMELSPEVKPIHLSPSKMLEPIPTAAEEESLEERVKSEVQMEESQESICEQDMGALNIATTAAVPVQNVDSCTLLLHQGEALGAMEQDQEDLQSCPPPYQVVACQVEDEAQAETEGRAETCSVHMDYDSSLVHPENETPEMDLTPQREEASVAMDLQGADVPRGREFPSLPPEESEQGPEMPSYPDEAISCQIPTLDIKPGDPLAGMNALVAATEMPQACSLLTTASVAPSQVQMEVLPDQALEHSFLQGITLLSEIAEMELEKRKQEMQTGPESFPVRPTLESLLAASTHMLMEVLSTPFMESLKTIRLPRELNPNKKYSWMQKKDEPMYSIKSAIENMDAMELDYRMRLAELQRRYKEKQRELVKLQRRRDSEEKHDEKSRSLARRGPGRPRKRKLGSSALSPIKERGKSDSKSGKLSKSLLLSEDSETGEGMKKRHKGALPEEDDDVESGSGKMKGRNQSWEEHDAAPSFSNELKLKKKKVPSDQEQLASKLDKALSLTKQDKLKSPFKFADSSGGKLKAGGGGSRYLPSHEALPSKEEKKSLAKNLGLSLKSTKEGKNKVAAKMKKMEVGLKVKNQLKVSHSPAISEVSSYSYNTDSEEEEEGSLRDEWPAQPPSAPKPRPPSLYSAAARKGGRAAGSLKAAPRGVAAGRPLKAKAAAGRKQPFCLLLREAEAGSSFSDSSEDSFDQDSSSEEEEEEDEEEEEEVEDYGTDSTDRLSSPALDESGLGLLARFAASAMPSPIVPPPLSIIQLEAKQKAKKKEERQSLMGTEFEYTDSESEIKIRKKSPSGLLRGKKGSLETSSIPSSQTPSSLEPGSGSVDKAKLGSEKGRKLKKFKSPKDLSFEFGLEASDDDLWNRRRSERIFLHDATTSSAILTPTAPASSTPVSKPGRCGKGAPMSPKKEGSKGKDRKELSKRKKGKEAPCCSSSSSMSPPGIPSSPSDVRVSLANALGSTKKSKAKVKAKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDENIPLSMLVERPPTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVKTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVKPPSVRFLPEGTRIAAYWSQQYRCLYPGTVVRGTLDLEEDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSTKRRSRKSSKDAGEGKEGATLGSEEPASKGKGRGRKPSIKAKAEEASLPEEKDQTEPSPGASSVPEKPACLGKSSVKGSRKSQPLPAGGSPAPTEEKRSKASKMKISAKLHSPPQPTYQPAVFGSILSTEPYSDLPGTLTAFGSSDASASKAKAKKGRPTEEAQEFGTMVKAQRKHDNEILIKLDHEGVMSPKTKKMKEAMRMLEDSSLAGRRDGKSLLGLGYSPAVGAEGKQKSSRAKAAEGDPASFGGKFDASAESLTASKDQEDKAAAPAAVEESESNSSDSSSESEGEEETEKNRGEAQDSSSTSSRASTPLSSSNSSSSSSSSSSSSSSSSSSSSSASSTSSSSSSSSSSSSTTDEDSSCSSDDEVAEAQPSSSVQQTLPPKQTKQTGKSRASSHPQSQKQPAQQPAQQPAPQQSGNKSRPKKREGIHLPTTKELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEIIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETNPGKKLNEGKRWDQKSGRSLSTALQASNQRKDFMERALYQSSHVDENDVQTISHKCLVVGLDQYEQMLKTKKYQDSEDLYYLAGTYEPTTGMIFNTDGVPVIC", "length": 2929, "header": "tr|A0A8V0ZIC2-1|A0A8V0ZIC2_CHICK Isoform 1 of Trinucleotide repeat containing 18 OS=Gallus gallus OX=9031 GN=TNRC18 PE=4 SV=1 CANONICAL=A0A8V0ZIC2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC2/entry#A0A8V0ZB94-1", "sequence": { "sequence": "MAPAATFPPQPVHSSVYTIFPPAKELGREHKVIAPTFVPSVEAYDERSGPIQIASQARDNKAKEKELGKAGVLQSPPERCLADASRALLSQDFSCHGDAKRMEVLREKGSVIRANSMALKRQVASEPFLNRPGLGSPESREFLASKDLLKSSPEAEHRPCERERFQRSSSKEATKVYGTLDSSRQHLDHSQLKPPEQKWKPFEMGNFATTQMAVLAAQHNHVTRAEEEAKKVYLDPSGLPRSSVVGSRGAADVLHPTSHSEGSAMQSLIKYSGSFAKETASRQSCGKKSPFGGLGNMKLDSSQLGTSKVQQLLTQQPAKQLKRDPERPESAKSFGRESIGSQGEVEVRHLPVGIAVAVARQKDNSSSSSGSKLTPSLADRDRSLSLSSIKGHSRSEDDCGDERSRHRDSHLLAGRLERDQEKLLRESKELVDFARIHPSGCATNGLNSNLMVTGGPALAGSGRWSTDPASHLAAHPWLPRTGSPSMWLAGHPYGLGHPSLHQGMTPGFPPAMGGALPSAYQFARDPQSGQLVVIPSEHLPHFAELMDRAPPLWPAMYPPTRSSLQHAHQLQLLSHQQLLRQHELYILQQQAAHAMELQRSAQLVERLKANEQRADMEEKVTKRSLDSAKSGLSSSAPGLVHRKPPVLSPSASTSYSKAVSPPPLSPRASPVSVLKAEVIQKMEEPPSQPAYSYPATPSSHPSSPPPASPPPAPAIPPKEEAPESVEKKDLELEKEAAGPFQALFQEIPPGYPFQSLPPSFGRHYPYLLQPTAAADADGLAPDVPLPAEGSEHMELSPEVKPIHLSPSKMLEPIPTAAEEESLEERVKSEVQMEESQESICEQDMGALNIATTAAVPVQNVDSCTLLLHQGEALGAMEQDQEDLQSCPPPYQVVACQVEDEAQAETEGRAETCSVHMDYDSSLVHPENETPEMDLTPQREEASVAMDLQGADVPRGREFPSLPPEESEQGPEMPSYPDEAISCQIPTLDIKPGDPLAGMNALVAATEMPQACSLLTTASVAPSQVQMEVLPDQALEHSFLQGITLLSEIAEMELEKRKQEMQTGPESFPVRPTLESLLAASTHMLMEVLSTPFMESLKTIRLPRELNPNKKYSWMQKKDEPMYSIKSAIENMDAMELDYRMRLAELQRRYKEKQRELVKLQRRRDSELSKSLLLSEDSETGEGMKKRHKGALPEEDDDVESGSGKMKGRNQSWEEHDAAPSFSNELKLKKKKVPSDQEQLASKLDKALSLTKQDKLKSPFKFADSSGGKLKAGGGGSRYLPSHEALPSKEEKKSLAKNLGLSLKSTKEGKNKVAAKMKKMEVGLKVKNQLKVSHSPAISEVSSYSYNSSSEEEEEEDEEEEEEVEDYGTDSTDRLSSPALDESGLGLLARFAASAMPSPIVPPPLSIIQLEAKQKAKKKEERQSLMGTEFEYTDSESEIKIRKKSPSGLLRGKKGSLETSSIPSSQTPSSLEPGSGSVDKAKLGSEKGRKLKKFKSPKDLSFEFGLEASDDDLWNRRRSERIFLHDATTSSAILTPTAPASSTPVSKPGRCGKGAPMSPKKEGSKGKDRKELSKRKKGKEAPCCSSSSSMSPPGIPSSPSDVRVSLANALGSTKKSKAKVKAKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDENIPLSMLVERPPTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVKTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVKPPSVRFLPEGTRIAAYWSQQYRCLYPGTVVRGTLDLEEDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSTKRRSRKSSKDAGEGKEGATLGSEEPASKGKGRGRKPSIKAKAEEASLPEEKDQTEPSPGASSVPEKPACLGKSSVKGSRKSQPLPAGGSPAPTEEKRSKASKMKISAKLHSPPQPTYQPAVFGSILSTEPYSDLPGTLTAFGSSDASASKAKAKKGRPTEEAQEFGTMVKAQRKHDNEILIKLDHEGVMSPKTKKMKEAMRMLEDSSLAGRRDGKSLLGLGYSPAVGAEGKQKSSRAKAAEGDPASFGGKFDASAESLTASKDQEDKAAAPAAVEESESNSSDSSSESEGEEETEKNRGEAQDSSSTSSRASTPLSSSNSSSSSSSSSSSSSSSSSSSSSASSTSSSSSSSSSSSSTTDEDSSCSSDDEVAEAQPSSSVQQTLPPKQTKQTGKSRASSHPQSQKQPAQQPAQQPAPQQSGNKSRPKKREGIHLPTTKELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEIIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETNPGKKLNEGKRWDQKSGRSLSTALQASNQRKDFMERALYQSSHVDENDVQTISHKCLVVGLDQYEQMLKTKKYQDSEDLYYLAGTYEPTTGMIFNTDGVPVIC", "length": 2471, "header": "tr|A0A8V0ZB94-1|A0A8V0ZIC2_CHICK Computationally mapped isoform of Trinucleotide repeat containing 18 OS=Gallus gallus OX=9031 GN=TNRC18 PE=4 SV=1 CANONICAL=A0A8V0ZIC2-1" }, "locus": { "chromosome": "14", "start_pos": 4128725, "end_pos": 4095891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051351.1", "url": "https://www.ensembl.org/id/ENSGALT00010051351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030542.1", "url": "https://www.ensembl.org/id/ENSGALP00010030542.1" } ] } }, { "isoform_ac": "A0A8V0ZIC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC2/entry#A0A8V0ZIC2-1", "sequence": { "sequence": "MMDGRDFGPPPRSAHGPPPPLLSGLPMDGHRLAAGRLPPSAPLAAGLPAALQPGKFLASGIGLHAHPGFSHLPNGLYPSYIPLSHLEPPSTGSPLLAQLGQHSLFESQKDGFYLSSHAAQSALHPQPPLARSAGSHTPSALLREKELGQLHKSSKESLKDPGGKERGCRTELSLPFAKKEGRPKEEPRPRSVVDLTQDSKPEGERKVSVVEKAAKAGERLSPFLAEHVPSRGGGGGEAKSKNPLQSSSLSNCNGGGDPVLKVLGAEQDRCAKDPARHDENVRPSAHAHAERLKRGETLLPSVGALHVSCSCPSPHPSQPGKMAPAATFPPQPVHSSVYTIFPPAKELGREHKVIAPTFVPSVEAYDERSGPIQIASQARDNKAKEKELGKAGVLQSPPERCLADASRALLSQDFSCHGDAKRMEVLREKGSVIRANSMALKRQVASEPFLNRPGLGSPESREFLASKDLLKSSPEAEHRPCERERFQRSSSKEATKVYGTLDSSRQHLDHSQLKPPEQKWKPFEMGNFATTQMAVLAAQHNHVTRAEEEAKKVYLDPSGLPRSSVVGSRGAADVLHPTSHSEGSAMQSLIKYSGSFAKETASRQSCGKKSPFGGLGNMKLDSSQLGTSKVQQLLTQQPAKQLKRDPERPESAKSFGRESIGSQGEVEVRHLPVGIAVAVARQKDNSSSSSGSKLTPSLADRDRSLSLSSIKGHSRSEDDCGDERSRHRDSHLLAGRLERDQEKLLRESKELVDFARIHPSGCATNGLNSNLMVTGGPALAGSGRWSTDPASHLAAHPWLPRTGSPSMWLAGHPYGLGHPSLHQGMTPGFPPAMGGALPSAYQFARDPQSGQLVVIPSEHLPHFAELMDRAPPLWPAMYPPTRSSLQHAHQLQLLSHQQLLRQHELYILQQQAAHAMELQRSAQLVERLKANEQRADMEEKVTKRSLDSAKSGLSSSAPGLVHRKPPVLSPSASTSYSKAVSPPPLSPRASPVSVLKAEVIQKMEEPPSQPAYSYPATPSSHPSSPPPASPPPAPAIPPKEEAPESVEKKDLELEKEAAGPFQALFQEIPPGYPFQSLPPSFGRHYPYLLQPTAAADADGLAPDVPLPAEGSEHMELSPEVKPIHLSPSKMLEPIPTAAEEESLEERVKSEVQMEESQESICEQDMGALNIATTAAVPVQNVDSCTLLLHQGEALGAMEQDQEDLQSCPPPYQVVACQVEDEAQAETEGRAETCSVHMDYDSSLVHPENETPEMDLTPQREEASVAMDLQGADVPRGREFPSLPPEESEQGPEMPSYPDEAISCQIPTLDIKPGDPLAGMNALVAATEMPQACSLLTTASVAPSQVQMEVLPDQALEHSFLQGITLLSEIAEMELEKRKQEMQTGPESFPVRPTLESLLAASTHMLMEVLSTPFMESLKTIRLPRELNPNKKYSWMQKKDEPMYSIKSAIENMDAMELDYRMRLAELQRRYKEKQRELVKLQRRRDSEEKHDEKSRSLARRGPGRPRKRKLGSSALSPIKERGKSDSKSGKLSKSLLLSEDSETGEGMKKRHKGALPEEDDDVESGSGKMKGRNQSWEEHDAAPSFSNELKLKKKKVPSDQEQLASKLDKALSLTKQDKLKSPFKFADSSGGKLKAGGGGSRYLPSHEALPSKEEKKSLAKNLGLSLKSTKEGKNKVAAKMKKMEVGLKVKNQLKVSHSPAISEVSSYSYNTDSEEEEEGSLRDEWPAQPPSAPKPRPPSLYSAAARKGGRAAGSLKAAPRGVAAGRPLKAKAAAGRKQPFCLLLREAEAGSSFSDSSEDSFDQDSSSEEEEEEDEEEEEEVEDYGTDSTDRLSSPALDESGLGLLARFAASAMPSPIVPPPLSIIQLEAKQKAKKKEERQSLMGTEFEYTDSESEIKIRKKSPSGLLRGKKGSLETSSIPSSQTPSSLEPGSGSVDKAKLGSEKGRKLKKFKSPKDLSFEFGLEASDDDLWNRRRSERIFLHDATTSSAILTPTAPASSTPVSKPGRCGKGAPMSPKKEGSKGKDRKELSKRKKGKEAPCCSSSSSMSPPGIPSSPSDVRVSLANALGSTKKSKAKVKAKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDENIPLSMLVERPPTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVKTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVKPPSVRFLPEGTRIAAYWSQQYRCLYPGTVVRGTLDLEEDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSTKRRSRKSSKDAGEGKEGATLGSEEPASKGKGRGRKPSIKAKAEEASLPEEKDQTEPSPGASSVPEKPACLGKSSVKGSRKSQPLPAGGSPAPTEEKRSKASKMKISAKLHSPPQPTYQPAVFGSILSTEPYSDLPGTLTAFGSSDASASKAKAKKGRPTEEAQEFGTMVKAQRKHDNEILIKLDHEGVMSPKTKKMKEAMRMLEDSSLAGRRDGKSLLGLGYSPAVGAEGKQKSSRAKAAEGDPASFGGKFDASAESLTASKDQEDKAAAPAAVEESESNSSDSSSESEGEEETEKNRGEAQDSSSTSSRASTPLSSSNSSSSSSSSSSSSSSSSSSSSSASSTSSSSSSSSSSSSTTDEDSSCSSDDEVAEAQPSSSVQQTLPPKQTKQTGKSRASSHPQSQKQPAQQPAQQPAPQQSGNKSRPKKREGIHLPTTKELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEIIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETNPGKKLNEGKRWDQKSGRSLSTALQASNQRKDFMERALYQSSHVDENDVQTISHKCLVVGLDQYEQMLKTKKYQDSEDLYYLAGTYEPTTGMIFNTDGVPVIC", "length": 2929, "header": "tr|A0A8V0ZIC2-1|A0A8V0ZIC2_CHICK Isoform 1 of Trinucleotide repeat containing 18 OS=Gallus gallus OX=9031 GN=TNRC18 PE=4 SV=1 CANONICAL=A0A8V0ZIC2-1" }, "locus": { "chromosome": "14", "start_pos": 4139201, "end_pos": 4095891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051354.1", "url": "https://www.ensembl.org/id/ENSGALT00010051354.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030545.1", "url": "https://www.ensembl.org/id/ENSGALP00010030545.1" } ] } }, { "isoform_ac": "A0A8V0ZIC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC2/entry#A0A8V0ZIC8-1", "sequence": { "sequence": "MMDGRDFGPPPRSAHGPPPPLLSGLPMDGHRLAAGRLPPSAPLAAGLPAALQPGKFLASGIGLHAHPGFSHLPNGLYPSYIPLSHLEPPSTGSPLLAQLGQHSLFESQKDGFYLSSHAAQSALHPQPPLARSAGSHTPSALLREKELGQLHKSSKESLKDPGGKERGCRTELSLPFAKKEGRPKEEPRPRSVVDLTQDSKPEGERKVSVVEKAAKAGERLSPFLAEHVPSRGGGGGEAKSKNPLQSSSLSNCNGGGDPVLKVLGAEQDRCAKDPARHDENVRPSAHAHAERLKRGETLLPSVGALHVSCSCPSPHPSQPGKMAPAATFPPQPVHSSVYTIFPPAKELGREHKVIAPTFVPSVEAYDERSGPIQIASQARDNKAKEKELGKAGVLQSPPERCLADASRALLSQDFSCHGDAKRMEVLREKGSVIRANSMALKRQVASEPFLNRPGLGSPESREFLASKDLLKSSPEAEHRPCERERFQRSSSKEATKVYGTLDSSRQHLDHSQLKPPEQKWKPFEMGNFATTQMAVLAAQHNHVTRAEEEAKKVYLDPSGLPRSSVVGSRGAADVLHPTSHSEGSAMQSLIKYSGSFAKETASRQSCGKKSPFGGLGNMKLDSSQLGTSKVQQLLTQQPAKQLKRDPERPESAKSFGRESIGSQGEVEVRHLPVGIAVAVARQKDNSSSSSGSKLTPSLADRDRSLSLSSIKGHSRSEDDCGDERSRHRDSHLLAGRLERDQEKLLRESKELVDFARIHPSGCATNGLNSNLMVTGGPALAGSGRWSTDPASHLAAHPWLPRTGSPSMWLAGHPYGLGHPSLHQGMTPGFPPAMGGALPSAYQFARDPQSGQLVVIPSEHLPHFAELMDRAPPLWPAMYPPTRSSLQHAHQLQLLSHQQLLRQHELYILQQQAAHAMELQRSAQLVERLKANEQRADMEEKVTKRSLDSAKSGLSSSAPGLVHRKPPVLSPSASTSYSKAVSPPPLSPRASPVSVLKAEVIQKMEEPPSQPAYSYPATPSSHPSSPPPASPPPAPAIPPKEEAPESVEKKDLELEKEAAGPFQALFQEIPPGYPFQSLPPSFGRHYPYLLQPTAAADADGLAPDVPLPAEGSEHMELSPEVKPIHLSPSKMLEPIPTAAEEESLEERVKSEVQMEESQESICEQDMGALNIATTAAVPVQNVDSCTLLLHQGEALGAMEQDQEDLQSCPPPYQVVACQVEDEAQAETEGRAETCSVHMDYDSSLVHPENETPEMDLTPQREEASVAMDLQGADVPRGREFPSLPPEESEQGPEMPSYPDEAISCQIPTLDIKPGDPLAGMNALVAATEMPQACSLLTTASVAPSQVQMEVLPDQALEHSFLQGITLLSEIAEMELEKRKQEMQTGPESFPVRPTLESLLAASTHMLMEVLSTPFMESLKTIRLPRELNPNKKYSWMQKKDEPMYSIKSAIENMDAMELDYRMRLAELQRRYKEKQRELVKLQRRRDSELSKSLLLSEDSETGEGMKKRHKGALPEEDDDVESGSGKMKGRNQSWEEHDAAPSFSNELKLKKKKVPSDQEQLASKLDKALSLTKQDKLKSPFKFADSSGGKLKAGGGGSRYLPSHEALPSKEEKKSLAKNLGLSLKSTKEGKNKVAAKMKKMEVGLKVKNQLKVSHSPAISEVSSYSYNTDSEEEEEGSLRDEWPAQPPSAPKPRPPSLYSAAARKGGRAAGSLKAAPRGVAAGRPLKAKAAAGRKQPFCLLLREAEAGSSFSDSSEDSFDQDSSSEEEEEEDEEEEEEVEDYGTDSTDRLSSPALDESGLGLLARFAASAMPSPIVPPPLSIIQLEAKQKAKKKEERQSLMGTEFEYTDSESEIKIRKKSPSGLLRGKKGSLETSSIPSSQTPSSLEPGSGSVDKAKLGSEKGRKLKKFKSPKDLSFEFGLEASDDDLWNRRRSERIFLHDATTSSAILTPTAPASSTPVSKPGRCGKGAPMSPKKEGSKGKDRKELSKRKKGKEAPCCSSSSSMSPPGIPSSPSDVRVSLANALGSTKKSKAKVKAKEVKKENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDENIPLSMLVERPPTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVKTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVKPPSVRFLPEGTRIAAYWSQQYRCLYPGTVVRGTLDLEEDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSTKRRSRKSSKDAGEGKEGATLGSEEPASKGKGRGRKPSIKAKAEEASLPEEKDQTEPSPGASSVPEKPACLGKSSVKGSRKSQPLPAGGSPAPTEEKRSKASKMKISAKLHSPPQPTYQPAVFGSILSTEPYSDLPGTLTAFGSSDASASKAKAKKGRPTEEAQEFGTMVKAQRKHDNEILIKLDHEGVMSPKTKKMKEAMRMLEDSSLAGRRDGKSLLGLGYSPAVGAEGKQKSSRAKAAEGDPASFGGKFDASAESLTASKDQEDKAAAPAAVEESESNSSDSSSESEGEEETEKNRGEAQDSSSTSSRASTPLSSSNSSSSSSSSSSSSSSSSSSSSSASSTSSSSSSSSSSSSTTDEDSSCSSDDEVAEAQPSSSVQQTLPPKQTKQTGKSRASSHPQSQKQPAQQPAQQPAPQQSGNKSRPKKREGIHLPTTKELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEIIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETNPGKKLNEGKRWDQKSGRSLSTALQASNQRKDFMERALYQSSHVDENDVQTISHKCLVVGLDQYEQMLKTKKYQDSEDLYYLAGTYEPTTGMIFNTDGVPVIC", "length": 2886, "header": "tr|A0A8V0ZIC8-1|A0A8V0ZIC8_CHICK Computationally mapped isoform of Trinucleotide repeat containing 18 OS=Gallus gallus OX=9031 GN=TNRC18 PE=4 SV=1 CANONICAL=A0A8V0ZIC2-1" }, "locus": { "chromosome": "14", "start_pos": 4139201, "end_pos": 4095891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051359.1", "url": "https://www.ensembl.org/id/ENSGALT00010051359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030550.1", "url": "https://www.ensembl.org/id/ENSGALP00010030550.1" } ] } }, { "isoform_ac": "A0A8V0ZPA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC2/entry#A0A8V0ZPA7-1", "sequence": { "sequence": 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"length": 1136, "header": "tr|A0A8V0ZPA7-1|A0A8V0ZPA7_CHICK Computationally mapped isoform of Trinucleotide repeat containing 18 OS=Gallus gallus OX=9031 GN=TNRC18 PE=4 SV=1 CANONICAL=A0A8V0ZIC2-1" }, "locus": { "chromosome": "14", "start_pos": 4110545, "end_pos": 4095891, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051347.1", "url": "https://www.ensembl.org/id/ENSGALT00010051347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030538.1", "url": "https://www.ensembl.org/id/ENSGALP00010030538.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1017, "start_aa": "Thr", "end_pos": 1017, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1017", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2131, "start_aa": "Thr", "end_pos": 2131, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2131", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416482", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416482", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": 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"id": "A0A8V0ZIE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GRVPAVGFPASPLRADASPPGGLTLGNGHRGDGKDKFVLGRTLCSERRPWGVPDFCCKECVSWNAAIQQGEATCLTEMSVMMACWKQNDFNDKSCAEEIRAFYDCVAKAEKERKEKKDEYALSLKGNIPSSKVNRLLRRFPNITRYV", "length": 147, "header": "tr|A0A8V0ZIE0-1|A0A8V0ZIE0_CHICK Isoform 1 of Coiled-coil-helix-coiled-coil-helix domain containing 1 OS=Gallus gallus OX=9031 GN=CHCHD1 PE=4 SV=1 CANONICAL=A0A8V0ZIE0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE0/entry#A0A8V0ZBB3-1", "sequence": { "sequence": "MAAPVYPAWVGRWISGQWRQRKRPPAVRPTRPLVLANKVANRRELAGEATCLTEMSVMMACWKQNDFNDKSCAEEIRAFYDCVAKAEKERKEKKDEYALSLKGNIPSSKVNRLLRRLSLKTFYGGSTDFSTFS", "length": 133, "header": "tr|A0A8V0ZBB3-1|A0A8V0ZIE0_CHICK Computationally mapped isoform of Coiled-coil-helix-coiled-coil-helix domain containing 1 OS=Gallus gallus OX=9031 GN=CHCHD1 PE=4 SV=1 CANONICAL=A0A8V0ZIE0-1" }, "locus": { "chromosome": "6", "start_pos": 16699229, "end_pos": 16695409, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051371.1", "url": "https://www.ensembl.org/id/ENSGALT00010051371.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030562.1", "url": "https://www.ensembl.org/id/ENSGALP00010030562.1" } ] } }, { "isoform_ac": "A0A8V0ZIE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE0/entry#A0A8V0ZIE0-1", "sequence": { "sequence": "GRVPAVGFPASPLRADASPPGGLTLGNGHRGDGKDKFVLGRTLCSERRPWGVPDFCCKECVSWNAAIQQGEATCLTEMSVMMACWKQNDFNDKSCAEEIRAFYDCVAKAEKERKEKKDEYALSLKGNIPSSKVNRLLRRFPNITRYV", "length": 147, "header": "tr|A0A8V0ZIE0-1|A0A8V0ZIE0_CHICK Isoform 1 of Coiled-coil-helix-coiled-coil-helix domain containing 1 OS=Gallus gallus OX=9031 GN=CHCHD1 PE=4 SV=1 CANONICAL=A0A8V0ZIE0-1" }, "locus": { "chromosome": "6", "start_pos": 16699030, "end_pos": 16697583, "strand": "+", "evidence": [ { "database": "Ensembl 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4, "go_terms": [ { "name": "mitochondrial ribosome", "id": "GO:0005761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005761", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE0" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE0" }, { "id": "PF06747", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06747" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CHCH", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 107, "start_aa": "Cys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIR2-1", "uniprot_ac": "A0A8V0ZIR2", "uniprot_id": "A0A8V0ZIR2_CHICK", "mass": { "chemical_mass": 96509.0, "monoisotopic_mass": 96509.0 }, "refseq": {}, "gene_names": [ { "name": "BCAR3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2" } ] } ], "protein_names": [ { "name": "BCAR3 adaptor protein, NSP family member", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BCAR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2", "locus": { "chromosome": "8", "start_pos": 13601115, "end_pos": 13524917, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021242", "url": "https://www.ensembl.org/id/ENSGALG00010021242" } ] } } ], "crossref": [ { "id": "A0A8V0ZIR2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIR2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424494", "url": "https://www.ncbi.nlm.nih.gov/gene/424494", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MDPAMEY", "url": "https://omabrowser.org/oma/group/MDPAMEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIR1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIS1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14247:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14247:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZBN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRAVLYVSRRPAGSAPAELQLVLAESRMIAAGKFSSLPRNVPVNVNHQFSLASSMDLLTTKPSLTEHRSDSFQDISIHGTLPRKKKGTVKVRACDMFSHVGMLPYTRTQRQQPPFVQDVIEEYPLQNGKSNKLHTRDQNIPDPTLEYVKFSKERQVMDNSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEDLVQRDGDFLIRDSLSCPGNFVLTCQWKNTSQHFKINRTILRLSEAYCRVQYQFELESFDSIPGLVRYYVGNRTPISKQSGAIIFQPINRTVPLRCLEEKYGVIPDRQKEQSIPEGKTEAAKRLSLGISSMQSQEQSVPRGNLLRNKEKSGSQPASLDHVLDKRFPLKTHQSESYLLIGSRHSSRLPEADADSCPSSPAFRTGSEPSLSPTVVQKVTYDSQVGEALRGSDSQLYPKPPPKPSKATLLKTTDSPMASHSSEGHYCELSLVRDSAATEHLCQKNSYVEHLTQKERGRQCFRNSETSYLILDDDHTVNSAGPLDVSTETAEENNVFSAPLFETSSSFKPNDFESKLLPSENKPLETSMLRKIKELFTKNNPKVIAQHILRMDCKVARILEVSEEMRRIMGVNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKDSLGDLYAFSAIMKALEMPQVSRLEQTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQEMVSVPQNLTLPLLMPLVTLMERQAVIFEGMDLWESSDQSCEIMFKHLTTARQIAQNAEMYSLTAQRMLEGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI", "length": 852, "header": "tr|A0A8V0ZIR2-1|A0A8V0ZIR2_CHICK Isoform 1 of BCAR3 adaptor protein, NSP family member OS=Gallus gallus OX=9031 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A8V0ZIR2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2/entry#A0A8V0ZBN2-1", "sequence": { "sequence": "MLGGRESRMIAAGKFSSLPRNVPVNVNHQFSLASSMDLLTTKPSLTEHRSDSFQDISIHGTLPRKKKGTVKVRACDMFSHVGMLPYTRTQRQQPPFVQDVIEEYPLQNGKSNKLHTRDQNIPDPTLEYVKFSKERQVMDNSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEDLVQRDGDFLIRDSLSCPGNFVLTCQWKNTSQHFKINRTILRLSEAYCRVQYQFELESFDSIPGLVRYYVGNRTPISKQSGAIIFQPINRTVPLRCLEEKYGVIPDRQKEQSIPEGKTEAAKRLSLGISSMQSQEQSVPRGNLLRNKEKSGSQPASLDHVLDKRFPLKTHQSESYLLIGSRHSSRLPEADADSCPSSPAFRTGSEPSLSPTVVQKVTYDSQVGEALRGSDSQLYPKPPPKPSKATLLKTTDSPMASHSSEGHYCELSLVRDSAATEHLCQKNSYVEHLTQKERGRQCFRNSETSYLILDDDHTVNSAGPLDVSTETAEENNVFSAPLFETSSSFKPNDFESKLLPSENKPLETSMLRKIKELFTKNNPKVIAQHILRMDCKVARILEVSEEMRRIMGVNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKDSLGDLYAFSAIMKALEMPQVSRLEQTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQEMVSVPQNLTLPLLMPLVTLMERQAVIFEGMDLWESSDQSCEIMFKHLTTARQIAQNAEMYSLTAQRMLEGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI", "length": 832, "header": "tr|A0A8V0ZBN2-1|A0A8V0ZIR2_CHICK Computationally mapped isoform of BCAR3 adaptor protein, NSP family member OS=Gallus gallus OX=9031 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A8V0ZIR2-1" }, "locus": { "chromosome": "8", "start_pos": 13600201, "end_pos": 13534941, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051496.1", "url": "https://www.ensembl.org/id/ENSGALT00010051496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030687.1", "url": "https://www.ensembl.org/id/ENSGALP00010030687.1" } ] } }, { "isoform_ac": "A0A8V0ZIR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2/entry#A0A8V0ZIR1-1", "sequence": { "sequence": "MPKDYNVFQMLIAALCCFYHRKSIIRVKFSKERQVMDNSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEDLVQRDGDFLIRDSLSCPGNFVLTCQWKNTSQHFKINRTILRLSEAYCRVQYQFELESFDSIPGLVRYYVGNRTPISKQSGAIIFQPINRTVPLRCLEEKYGVIPDRQKEQSIPEGKTEAAKRLSLGISSMQSQEQSVPRGNLLRNKEKSGSQPASLDHVLDKRFPLKTHQSESYLLIGSRHSSRLPEADADSCPSSPAFRTGSEPSLSPTVVQKVTYDSQVGEALRGSDSQLYPKPPPKPSKATLLKTTDSPMASHSSEGHYCELSLVRDSAATEHLCQKNSYVEHLTQKERGRQCFRNSETSYLILDDDHTVNSAGPLDVSTETAEENNVFSAPLFETSSSFKPNDFESKLLPSENKPLETSMLRKIKELFTKNNPKVIAQHILRMDCKVARILEVSEEMRRIMGVNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKDSLGDLYAFSAIMKALEMPQVSRLEQTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQEMVSVPQNLTLPLLMPLVTLMERQAVIFEGMDLWESSDQSCEIMFKHLTTARQIAQNAEMYSLTAQRMLEGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI", "length": 730, "header": "tr|A0A8V0ZIR1-1|A0A8V0ZIR1_CHICK Computationally mapped isoform of BCAR3 adaptor protein, NSP family member OS=Gallus gallus OX=9031 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A8V0ZIR2-1" }, "locus": { "chromosome": "8", "start_pos": 13600201, "end_pos": 13580357, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051489.1", "url": "https://www.ensembl.org/id/ENSGALT00010051489.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030680.1", "url": "https://www.ensembl.org/id/ENSGALP00010030680.1" } ] } }, { "isoform_ac": "A0A8V0ZIR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2/entry#A0A8V0ZIR2-1", "sequence": { "sequence": "MPRAVLYVSRRPAGSAPAELQLVLAESRMIAAGKFSSLPRNVPVNVNHQFSLASSMDLLTTKPSLTEHRSDSFQDISIHGTLPRKKKGTVKVRACDMFSHVGMLPYTRTQRQQPPFVQDVIEEYPLQNGKSNKLHTRDQNIPDPTLEYVKFSKERQVMDNSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEDLVQRDGDFLIRDSLSCPGNFVLTCQWKNTSQHFKINRTILRLSEAYCRVQYQFELESFDSIPGLVRYYVGNRTPISKQSGAIIFQPINRTVPLRCLEEKYGVIPDRQKEQSIPEGKTEAAKRLSLGISSMQSQEQSVPRGNLLRNKEKSGSQPASLDHVLDKRFPLKTHQSESYLLIGSRHSSRLPEADADSCPSSPAFRTGSEPSLSPTVVQKVTYDSQVGEALRGSDSQLYPKPPPKPSKATLLKTTDSPMASHSSEGHYCELSLVRDSAATEHLCQKNSYVEHLTQKERGRQCFRNSETSYLILDDDHTVNSAGPLDVSTETAEENNVFSAPLFETSSSFKPNDFESKLLPSENKPLETSMLRKIKELFTKNNPKVIAQHILRMDCKVARILEVSEEMRRIMGVNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKDSLGDLYAFSAIMKALEMPQVSRLEQTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQEMVSVPQNLTLPLLMPLVTLMERQAVIFEGMDLWESSDQSCEIMFKHLTTARQIAQNAEMYSLTAQRMLEGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI", "length": 852, "header": "tr|A0A8V0ZIR2-1|A0A8V0ZIR2_CHICK Isoform 1 of BCAR3 adaptor protein, NSP family member OS=Gallus gallus OX=9031 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A8V0ZIR2-1" }, "locus": { "chromosome": "8", "start_pos": 13600201, "end_pos": 13551996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051490.1", "url": "https://www.ensembl.org/id/ENSGALT00010051490.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030681.1", "url": "https://www.ensembl.org/id/ENSGALP00010030681.1" } ] } }, { "isoform_ac": "A0A8V0ZIR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2/entry#A0A8V0ZIR7-1", "sequence": { "sequence": "MKESRMIAAGKFSSLPRNVPVNVNHQFSLASSMDLLTTKPSLTEHRSDSFQDISIHGTLPRKKKGTVKVRACDMFSHVGMLPYTRTQRQQPPFVQDVIEEYPLQNGKSNKLHTRDQNIPDPTLEYVKFSKERQVMDNSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEDLVQRDGDFLIRDSLSCPGNFVLTCQWKNTSQHFKINRTILRLSEAYCRVQYQFELESFDSIPGLVRYYVGNRTPISKQSGAIIFQPINRTVPLRCLEEKYGVIPDRQKEQSIPEGKTEAAKRLSLGISSMQSQEQSVPRGNLLRNKEKSGSQPASLDHVLDKRFPLKTHQSESYLLIGSRHSSRLPEADADSCPSSPAFRTGSEPSLSPTVVQKVTYDSQVGEALRGSDSQLYPKPPPKPSKATLLKTTDSPMASHSSEGHYCELSLVRDSAATEHLCQKNSYVEHLTQKERGRQCFRNSETSYLILDDDHTVNSAGPLDVSTETAEENNVFSAPLFETSSSFKPNDFESKLLPSENKPLETSMLRKIKELFTKNNPKVIAQHILRMDCKVARILEVSEEMRRIMGVNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKDSLGDLYAFSAIMKALEMPQVSRLEQTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQEMVSVPQNLTLPLLMPLVTLMERQAVIFEGMDLWESSDQSCEIMFKHLTTARQIAQNAEMYSLTAQRMLEGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI", "length": 829, "header": "tr|A0A8V0ZIR7-1|A0A8V0ZIR7_CHICK Computationally mapped isoform of BCAR3 adaptor protein, NSP family member OS=Gallus gallus OX=9031 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A8V0ZIR2-1" }, "locus": { "chromosome": "8", "start_pos": 13600201, "end_pos": 13550672, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051494.1", "url": "https://www.ensembl.org/id/ENSGALT00010051494.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030685.1", "url": "https://www.ensembl.org/id/ENSGALP00010030685.1" } ] } }, { "isoform_ac": "A0A8V0ZIS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2/entry#A0A8V0ZIS1-1", "sequence": { "sequence": "MQQIAIKSLNGWTLTYLPCVDESRMIAAGKFSSLPRNVPVNVNHQFSLASSMDLLTTKPSLTEHRSDSFQDISIHGTLPRKKKGTVKVRACDMFSHVGMLPYTRTQRQQPPFVQDVIEEYPLQNGKSNKLHTRDQNIPDPTLEYVKFSKERQVMDNSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEDLVQRDGDFLIRDSLSCPGNFVLTCQWKNTSQHFKINRTILRLSEAYCRVQYQFELESFDSIPGLVRYYVGNRTPISKQSGAIIFQPINRTVPLRCLEEKYGVIPDRQKEQSIPEGKTEAAKRLSLGISSMQSQEQSVPRGNLLRNKEKSGSQPASLDHVLDKRFPLKTHQSESYLLIGSRHSSRLPEADADSCPSSPAFRTGSEPSLSPTVVQKVTYDSQVGEALRGSDSQLYPKPPPKPSKATLLKTTDSPMASHSSEGHYCELSLVRDSAATEHLCQKNSYVEHLTQKERGRQCFRNSETSYLILDDDHTVNSAGPLDVSTETAEENNVFSAPLFETSSSFKPNDFESKLLPSENKPLETSMLRKIKELFTKNNPKVIAQHILRMDCKVARILEVSEEMRRIMGVNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKDSLGDLYAFSAIMKALEMPQVSRLEQTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQEMVSVPQNLTLPLLMPLVTLMERQAVIFEGMDLWESSDQSCEIMFKHLTTARQIAQNAEMYSLTAQRMLEGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI", "length": 848, "header": "tr|A0A8V0ZIS1-1|A0A8V0ZIS1_CHICK Computationally mapped isoform of BCAR3 adaptor protein, NSP family member OS=Gallus gallus OX=9031 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A8V0ZIR2-1" }, "locus": { "chromosome": "8", "start_pos": 13600201, "end_pos": 13524963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051501.1", "url": "https://www.ensembl.org/id/ENSGALT00010051501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030691.1", "url": "https://www.ensembl.org/id/ENSGALP00010030691.1" } ] } }, { "isoform_ac": "A0A8V0ZIT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2/entry#A0A8V0ZIT0-1", "sequence": { "sequence": "MQIAIKSLNGWTLTYLPCVDESRMIAAGKFSSLPRNVPVNVNHQFSLASSMDLLTTKPSLTEHRSDSFQDISIHGTLPRKKKGTVKVRACDMFSHVGMLPYTRTQRQQPPFVQDVIEEYPLQNGKSNKLHTRDQNIPDPTLEYVKFSKERQVMDNSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEDLVQRDGDFLIRDSLSCPGNFVLTCQWKNTSQHFKINRTILRLSEAYCRVQYQFELESFDSIPGLVRYYVGNRTPISKQSGAIIFQPINRTVPLRCLEEKYGVIPDRQKEQSIPEGKTEAAKRLSLGISSMQSQEQSVPRGNLLRNKEKSGSQPASLDHVLDKRFPLKTHQSESYLLIGSRHSSRLPEADADSCPSSPAFRTGSEPSLSPTVVQKVTYDSQVGEALRGSDSQLYPKPPPKPSKATLLKTTDSPMASHSSEGHYCELSLVRDSAATEHLCQKNSYVEHLTQKERGRQCFRNSETSYLILDDDHTVNSAGPLDVSTETAEENNVFSAPLFETSSSFKPNDFESKLLPSENKPLETSMLRKIKELFTKNNPKVIAQHILRMDCKVARILEVSEEMRRIMGVNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKDSLGDLYAFSAIMKALEMPQVSRLEQTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQEMVSVPQNLTLPLLMPLVTLMERQAVIFEGMDLWESSDQSCEIMFKHLTTARQIAQNAEMYSLTAQRMLEGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI", "length": 847, "header": "tr|A0A8V0ZIT0-1|A0A8V0ZIT0_CHICK Computationally mapped isoform of BCAR3 adaptor protein, NSP family member OS=Gallus gallus OX=9031 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A8V0ZIR2-1" }, "locus": { "chromosome": "8", "start_pos": 13600201, "end_pos": 13524963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051504.1", "url": "https://www.ensembl.org/id/ENSGALT00010051504.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030695.1", "url": "https://www.ensembl.org/id/ENSGALP00010030695.1" } ] } }, { "isoform_ac": "A0A8V0ZPM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2/entry#A0A8V0ZPM9-1", "sequence": { "sequence": "MIAAGKFSSLPRNVPVNVNHQFSLASSMDLLTTKPSLTEHRSDSFQDISIHGTLPRKKKGTVKVRACDMFSHVGMLPYTRTQRQQPPFVQDVIEEYPLQNGKSNKLHTRDQNIPDPTLEYVKFSKERQVMDNSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEDLVQRDGDFLIRDSLSCPGNFVLTCQWKNTSQHFKINRTILRLSEAYCRVQYQFELESFDSIPGLVRYYVGNRTPISKQSGAIIFQPINRTVPLRCLEEKYGVIPDRQKEQSIPEGKTEAAKRLSLGISSMQSQEQSVPRGNLLRNKEKSGSQPASLDHVLDKRFPLKTHQSESYLLIGSRHSSRLPEADADSCPSSPAFRTGSEPSLSPTVVQKVTYDSQVGEALRGSDSQLYPKPPPKPSKATLLKTTDSPMASHSSEGHYCELSLVRDSAATEHLCQKNSYVEHLTQKERGRQCFRNSETSYLILDDDHTVNSAGPLDVSTETAEENNVFSAPLFETSSSFKPNDFESKLLPSENKPLETSMLRKIKELFTKNNPKVIAQHILRMDCKVARILEVSEEMRRIMGVNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKDSLGDLYAFSAIMKALEMPQVSRLEQTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQEMVSVPQNLTLPLLMPLVTLMERQAVIFEGMDLWESSDQSCEIMFKHLTTARQIAQNAEMYSLTAQRMLEGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI", "length": 824, "header": "tr|A0A8V0ZPM9-1|A0A8V0ZPM9_CHICK Computationally mapped isoform of BCAR3 adaptor protein, NSP family member OS=Gallus gallus OX=9031 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A8V0ZIR2-1" }, "locus": { "chromosome": "8", "start_pos": 13600201, "end_pos": 13558096, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051492.1", "url": "https://www.ensembl.org/id/ENSGALT00010051492.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030683.1", "url": "https://www.ensembl.org/id/ENSGALP00010030683.1" } ] } }, { "isoform_ac": "A0A8V0ZPP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2/entry#A0A8V0ZPP3-1", "sequence": { "sequence": "MITSLYESRMIAAGKFSSLPRNVPVNVNHQFSLASSMDLLTTKPSLTEHRSDSFQDISIHGTLPRKKKGTVKVRACDMFSHVGMLPYTRTQRQQPPFVQDVIEEYPLQNGKSNKLHTRDQNIPDPTLEYVKFSKERQVMDNSPEKLKKELEEELQLSSEDLRSHAWYHGRIPRQVAEDLVQRDGDFLIRDSLSCPGNFVLTCQWKNTSQHFKINRTILRLSEAYCRVQYQFELESFDSIPGLVRYYVGNRTPISKQSGAIIFQPINRTVPLRCLEEKYGVIPDRQKEQSIPEGKTEAAKRLSLGISSMQSQEQSVPRGNLLRNKEKSGSQPASLDHVLDKRFPLKTHQSESYLLIGSRHSSRLPEADADSCPSSPAFRTGSEPSLSPTVVQKVTYDSQVGEALRGSDSQLYPKPPPKPSKATLLKTTDSPMASHSSEGHYCELSLVRDSAATEHLCQKNSYVEHLTQKERGRQCFRNSETSYLILDDDHTVNSAGPLDVSTETAEENNVFSAPLFETSSSFKPNDFESKLLPSENKPLETSMLRKIKELFTKNNPKVIAQHILRMDCKVARILEVSEEMRRIMGVNSGLELITLPYGHQLRLDLIERHNTMAIGIAVDILGCTGNLEDRAATLNKIIQVAVELKDSLGDLYAFSAIMKALEMPQVSRLEQTWTSLRHHYTQTAIMYEKQLKPFSKALHEGQEMVSVPQNLTLPLLMPLVTLMERQAVIFEGMDLWESSDQSCEIMFKHLTTARQIAQNAEMYSLTAQRMLEGFQPDEEMSEIFKTEFQMRLLWGSKGAQVNQNERYEKFSQILTALSRKLEPPPVKQVEQLSI", "length": 833, "header": "tr|A0A8V0ZPP3-1|A0A8V0ZPP3_CHICK Computationally mapped isoform of BCAR3 adaptor protein, NSP family member OS=Gallus gallus OX=9031 GN=BCAR3 PE=4 SV=1 CANONICAL=A0A8V0ZIR2-1" }, "locus": { "chromosome": "8", "start_pos": 13600201, "end_pos": 13524947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051507.1", "url": "https://www.ensembl.org/id/ENSGALT00010051507.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030698.1", "url": "https://www.ensembl.org/id/ENSGALP00010030698.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A140T848-1", "protein_name": "BCAR3 adaptor protein, NSP family member", "gene_name": "BCAR3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLVERRADAYQDVSIHGTLPRKKKGPPPIRSCDNFSHVGTLPHSRSPRHHSPLIQDVIQEQPLQDWKGEAFTFSRVGRSLVTGVPVLQFSKERHVMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLMQRDGDFLVRDSLSSPGDFVLTCQWKNLPQHFKIRRTVVRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPVNRTVPLRCLEERYGASSPDRAHEGSLTEGRPDAAKRLSLTVGGTQAREQGLPRGNLLRNKEKSGSQPACLDHMQDRRALSLKAHQSESYLPIGGKLTPQSPSVGTSPCPNSPVFRTGSEPTLSPAVVRRVSSDARPGEALRGSDSQLCPKPPPKPCKAPLLKAPPSPSIWLNSEANYCELNPALAASYDGASRLPFCAQDSYVELLTAKQNGGLGTRNSDTSYLILDDDDRTRPWKPPPAPGDTVGEDQDTFVMPLLETTSSFKPNDFESKLLPPENKPLETSMLKRAKELFTNSDPKVIAQHLLSVDCKVARILEVSEEMRKNMGVNSGLELITLPYGHQLRLDIIERHNTMAIGIAVDILGCTGSLEDRAATLNKIIQVAVELKDSMGDLYSFSAIMKALEMPQITRLEKTWTALRHQYTQTAILYEKQLKPFSKVLHEGRESTCVPPNNVSVPLLMPLVTLMEREAVTFEGTDMWEKNDESCEIMLNHLATARLMAEAADSYRMNAEKILAGFQPDEEMSEVFKTEFQMRLLWGSKGAQVNQTERYEKFNQILTALSRKLEPPPVKQMEF", "length": 827 }, "evidence": [ { "id": "A0A8V0ZIR2", "url": "https://omabrowser.org/oma/group/A0A8V0ZIR2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZAZ5-1", "protein_name": "Breast cancer anti-estrogen resistance protein 3 homolog", "gene_name": "Bcar3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGKFASLPRHMPVNHQFPLASSMDLLSSKSPLAEHRTEAYPDVSIHGTLPRKKKGPPPIRSCDSASHMGTLPHSKSPRQSSPLTQDLILEKPLPDWKGDSFAFRDPYLLDPTLEYVKFSKERHIMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLWCLEERYGTSPGRGREGSFAEGRPDVVKRLSLTTGGIQARDHSLPRGNLLRNKDKSGSQPACLDHVQDRKAATLKAHQSESHLPIGCKLPPQSPSVDTSPCPNSPVFRTGSEPTLSPALVRRFSSDARAGEALRGSDSQLCPKPPPKPCKVPFLKVPPSPSPWLNSEANYCELNPAFAVGCDRGAKLLSQALDSHEMLLTAKQNGASGPRNSGINYSILDGDDQGRHWDPLAVQTDEGQEDETKFVPPVMETVSSFRPNDFESKLLPPENKPLETAMLKHAKELFTNHDARVIAQHMLSVDCKVARILEVSEDMKRSMGVSSGLELITLPHGRQLRLDIIERHNTMAIGIAVDILGCTGTLENRAGTLNKIIQVAMELKDTMGDLYSFSAIMKALEMPQITRLEKTWTALRHHYTQTAILYEKQLKPFSKILHEGRESTYVPASSVSVPLLMPLVTLMERQAVTFEGTDMWEKNDESCEIMLSHLATARFMAEASESYRMNAERVLADFQPDEEMTEILKTEFQMRLLWGSKGAEVNQNERYDKFNQILTALSRKLEPPSGKQAEL", "length": 825 }, "evidence": [ { "id": "A0A8V0ZIR2", "url": "https://omabrowser.org/oma/group/A0A8V0ZIR2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R3Z4-1", "protein_name": "Breast cancer anti-estrogen resistance protein 3 isoform X1", "gene_name": "bcar3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"https://omabrowser.org/oma/group/A0A8V0ZIR2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O75815-1", "protein_name": "Breast cancer anti-estrogen resistance protein 3", "gene_name": "BCAR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MAAGKFASLPRNMPVNHQFPLASSMDLLSSKSPLAERRTDAYQDVSIHGTLPRKKKGPPSIRSCDNAGHSKSPRQSSPLTQDIIQENPLQDRKGENFIFRDPYLLDPTLEYVKFSKERHIMDRTPERLKKELEEELLLSSEDLRSHAWYHGRIPRQVSENLVQRDGDFLVRDSLSSPGNFVLTCQWKNLAQHFKINRTVLRLSEAYSRVQYQFEMESFDSIPGLVRCYVGNRRPISQQSGAIIFQPINRTVPLWCLEERYGTSPGRGREGSLAEGRPDVVKRLSLTTGSSIQAREHSLPRGNLLRNKEKSGSQPACLDHVQDRKALTLKAHQSESHLPIGCKLPPQSPSMDTSPCPSSPVFRTGSEPTLSPALVRRFSSDARTGEALRGSDSQLCPKPPPKPCKVPFLKTPPSPSPWLTSEANYCELNPAFAVGCDRGAKLPMQAHDSHEMLLTAKQNGPSGPRNSGINYMILDGDDQARHWDPLAVQTDEGQEDKTKFVPPLMETVSSFRPNDFESKLLPPENKPLETAMLKHAKELFTNHDARVIAQHMLSVDCKVARILEVSEDRKRSMGVSSGLELITLPHGRQLRLDIIERHNTMAIGIAVDILGCTGTLENRAGTLNKIIQVAVELKDAMGDLYAFSAIMKALEMPQITRLEKTWTALRHHYTQTAILYEKQLKPFSKILHEGRESTYVPASNVSVPLLMPLVTLMERQAVTFEGTDMWENNDESCEILLNHLATARFMAEASESYRMNAERILADFQPDEEMTEILRTEFQMRLLWGSKGAEVNQNERYDKFNQILTALSRKLEPPSGKQAEL", "length": 820 }, "evidence": [ { "id": "A0A8V0ZIR2", "url": "https://omabrowser.org/oma/group/A0A8V0ZIR2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": 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{ "name": "epidermal growth factor receptor signaling pathway", "id": "GO:0007173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007173", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIR2", "url": 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}, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 728, "end_pos": 730 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"id": "A0A8V0ZHD6", "url": "https://www.orthodb.org/?gene=A0A8V0ZHD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIV0", "url": "https://www.orthodb.org/?gene=A0A8V0ZIV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45842:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZBQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGERVVVIRVRRGGRMGPLLCCLGIAVLLCRGLACPGPCSCSTKKNGRLLAECAYKELPEVPRGLSPNVTILTLSANRIGWLWRGAFAEVPEVQSLWLGYNQIGGAEPGAFATLSQLKNLDLSHNKMVTFPWQDLRNLSGLQILKLNNNRLAGLPRDAFQALAELRSLWLNDNQLTTLADGTFHPLPSLSQLQLFNNPFNCSCKLFWLKRWAESTSVSLTKGGSTLCAAPGRMRGRAVTDIPAHQCVAPSVQLTYLSKLDNTVLPDGLTLSLHCSVAGSPLPQIRWRIQTPGRGVEIDGPNVARDGSLSPSGRVKQSQERFLVFKNGTMAIPKFSKEDEGTYTCIAINDVGTREVSVNVALAGSENPAEDLLQDDPHASPLGGRSCYKGDEMDPVGAGEKLVIVYHVPREVKGTAGGAVPQVGLVTLLLALGIVLGW", "length": 437, "header": "tr|A0A8V0ZHD6-1|A0A8V0ZHD6_CHICK Isoform 1 of Immunoglobulin superfamily containing leucine rich repeat OS=Gallus gallus OX=9031 GN=ISLR PE=1 SV=1 CANONICAL=A0A8V0ZHD6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD6/entry#A0A8V0ZBQ5-1", "sequence": { "sequence": "MGPLLCCLGIAVLLCRGLACPGPCSCSTKKNGRLLAECAYKELPEVPRGLSPNVTILTLSANRIGWLWRGAFAEVPEVQSLWLGYNQIGGAEPGAFATLSQLKNLDLSHNKMVTFPWQDLRNLSGLQILKLNNNRLAGLPRDAFQALAELRSLWLNDNQLTTLADGTFHPLPSLSQLQLFNNPFNCSCKLFWLKRWAESTSVSLTKGGSTLCAAPGRMRGRAVTDIPAHQCVAPSVQLTYLSKLDNTVLPDGLTLSLHCSVAGSPLPQIRWRIQTPGRGVEIDGPNVARDGSLSPSGRVKQSQERFLVFKNGTMAIPKFSKEDEGTYTCIAINDVGTREVSVNVALAGSENPAEDLLQDDPHASPLGGRSCYKGDEMDPVGAGEKLVIVYHVPREVKGTAGGAVPQVGLVTLLLALGIVLGW", "length": 422, "header": "tr|A0A8V0ZBQ5-1|A0A8V0ZHD6_CHICK Computationally mapped isoform of Immunoglobulin superfamily containing leucine rich repeat OS=Gallus gallus OX=9031 GN=ISLR PE=1 SV=1 CANONICAL=A0A8V0ZHD6-1" }, "locus": { "chromosome": "10", "start_pos": 2628002, "end_pos": 2626737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051521.1", "url": "https://www.ensembl.org/id/ENSGALT00010051521.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030712.1", "url": "https://www.ensembl.org/id/ENSGALP00010030712.1" } ] } }, { "isoform_ac": "A0A8V0ZHD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD6/entry#A0A8V0ZHD6-1", "sequence": { "sequence": "MGERVVVIRVRRGGRMGPLLCCLGIAVLLCRGLACPGPCSCSTKKNGRLLAECAYKELPEVPRGLSPNVTILTLSANRIGWLWRGAFAEVPEVQSLWLGYNQIGGAEPGAFATLSQLKNLDLSHNKMVTFPWQDLRNLSGLQILKLNNNRLAGLPRDAFQALAELRSLWLNDNQLTTLADGTFHPLPSLSQLQLFNNPFNCSCKLFWLKRWAESTSVSLTKGGSTLCAAPGRMRGRAVTDIPAHQCVAPSVQLTYLSKLDNTVLPDGLTLSLHCSVAGSPLPQIRWRIQTPGRGVEIDGPNVARDGSLSPSGRVKQSQERFLVFKNGTMAIPKFSKEDEGTYTCIAINDVGTREVSVNVALAGSENPAEDLLQDDPHASPLGGRSCYKGDEMDPVGAGEKLVIVYHVPREVKGTAGGAVPQVGLVTLLLALGIVLGW", "length": 437, "header": "tr|A0A8V0ZHD6-1|A0A8V0ZHD6_CHICK Isoform 1 of Immunoglobulin superfamily containing leucine rich repeat OS=Gallus gallus OX=9031 GN=ISLR PE=1 SV=1 CANONICAL=A0A8V0ZHD6-1" }, "locus": { "chromosome": "10", "start_pos": 2628370, "end_pos": 2626737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051518.1", "url": "https://www.ensembl.org/id/ENSGALT00010051518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030709.1", "url": "https://www.ensembl.org/id/ENSGALP00010030709.1" } ] } }, { "isoform_ac": "A0A8V0ZIV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD6/entry#A0A8V0ZIV0-1", "sequence": { "sequence": "MGPLLCCLGIAVLLCRGLACPGPCSCSTKKNGRLLAECAYKELPEVQSLWLGYNQIGGAEPGAFATLSQLKNLDLSHNKMVTFPWQDLRNLSGLQILKLNNNRLAGLPRDAFQALAELRSLWLNDNQLTTLADGTFHPLPSLSQLQLFNNPFNCSCKLFWLKRWAESTSVSLTKGGSTLCAAPGRMRGRAVTDIPAHQCVAPSVQLTYLSKLDNTVLPDGLTLSLHCSVAGSPLPQIRWRIQTPGRGVEIDGPNVARDGSLSPSGRVKQSQERFLVFKNGTMAIPKFSKEDEGTYTCIAINDVGTREVSVNVALAGSENPAEDLLQDDPHASPLGGRSCYKGDEMDPVGAGEKLVIVYHVPREVKGTAGGAVPQVGLVTLLLALGIVLGW", "length": 390, "header": "tr|A0A8V0ZIV0-1|A0A8V0ZIV0_CHICK Computationally mapped isoform of Immunoglobulin superfamily containing leucine rich repeat OS=Gallus gallus OX=9031 GN=ISLR PE=1 SV=1 CANONICAL=A0A8V0ZHD6-1" }, "locus": { "chromosome": "10", "start_pos": 2628002, "end_pos": 2626737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051519.1", "url": "https://www.ensembl.org/id/ENSGALT00010051519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030710.1", "url": "https://www.ensembl.org/id/ENSGALP00010030710.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769957", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769957", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZHD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD6" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 249, "end_pos": 360, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZHK9-1", "uniprot_ac": "A0A8V0ZHK9", "uniprot_id": "A0A8V0ZHK9_CHICK", "mass": { "chemical_mass": 145935.0, "monoisotopic_mass": 145935.0 }, "refseq": {}, "gene_names": [ { "name": "RPGRIP1L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ] } ], "protein_names": [ { "name": "RPGRIP1 like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZHK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPGRIP1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9", "locus": { "chromosome": "11", "start_pos": 4581299, "end_pos": 4518013, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021298", "url": "https://www.ensembl.org/id/ENSGALG00010021298" } ] } } ], "crossref": [ { "id": "A0A8V0ZHK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00030", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00030", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "425392", "url": "https://www.ncbi.nlm.nih.gov/gene/425392", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425392", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425392", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HMERIRF", "url": "https://omabrowser.org/oma/group/HMERIRF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBY0", "url": "https://www.orthodb.org/?gene=A0A8V0ZBY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHK9", "url": "https://www.orthodb.org/?gene=A0A8V0ZHK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPY4", "url": "https://www.orthodb.org/?gene=A0A8V0ZPY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14240:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14240:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11618", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11618", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18111", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18111", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5610787", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZBY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAVGDETVGDMPVRDVGPTLPRVRGLLASARNVKARQAVSQFSRKELEDKYLQLRDENISLKQHANKQEETIKRMATRLIQLVHDKKRNEQVGGGPKRLGRTVKMEGMVEHLQERVRDLEKQNEILRSKLISNKQQIHMPSHRPIQYKFAQPRNSNGLKKASDAAGTPEPTKKGMRLQNLEVRSPPLVLRRCGPNLLEDARAKIRNLETVIDSQRGRIQELEHLSELLGSQLRNKEKEIEESALHLKEQEAARQRDKRSNIRDNVEMIKVRKQLAEKSSALAAMESKFLQLQENQRNFKTNHDVLIAKSEELNVQLKEERSKCLHLEKELQSVAISKRRTEELEERVNDLEREKELLKENCDKLSSSVFSMTREQEWKLKEEQLKLQIAELETAIQSSLADKDEILGKLKVERDKKEKLMEENKDLQSCYLENKQQLDELKDYMKYLTKRCDVDVAELSEALLLIKVRKEQKKNGDLICLEKDDDDIQKVSERSMRKLQLAHAETVQELEKTRSMLIVQHKINKGYQTEIEAVTQKMESLQKDYELKIGKYVDLLDMKAARIKKLEAQLRDVAYGSKRYKFRPEILPANPVNIFDETLHFERREGLFEIHISKVIFSSEAVHAFGDHEPATFCTYAFYDFELQATPVLHGHTLSYDFTSQYLAQIDDSFLHYIQSNSVTLEVHHAYGTDYETVATCQLALHEVLEQNGRIYSTAVLVGINGNIQDFGTVEYWVRLQAPMDQSIGLYKEKSKAQEYITPNFREHESPFQQQILRTAEVSASTSDGDLNELHVTIKCCNRLQSQKKHLQPNSYVVYKFFDFAHHDTRIIPSSSNPQIDDHMCFQVPMTADLDQYLKWESLTFYVFDDSEMGEDGFLGKANVPLIPLACNRSISGTFEVTDSERRVTGAIRVELKWKFAYLSPSGAAVAADLENNIQNEKSMAPKLLSEQEMQPPAFSPSFTSSVTVPIPKPRRHAPQTDKEVSLLNASSVQMRGAVESDMELKNKIETSTGPNALEVKQERPADVKVKETAKGIQQEKEDRSCLSEEQLTGQSSVTSGKETEITEEQEPEAGQDNRHRNDSIESETDSDDCIVTSPISKNIIQATEKIRIEIISLGLTESRIVEDNTIQQLFVECRLYNFIAEETPVSLPKPPCGQRVHYNYSNVIHVDKANNRARREYLKSILQKPSLRTDRLLFTVVSDPPEDEQDLECEDIGFAYVSLREIFEKKRDVIEQDIFVFDSQDDSAVIGKLRVTVEALHALCSVYEECEDDYEA", "length": 1273, "header": "tr|A0A8V0ZHK9-1|A0A8V0ZHK9_CHICK Isoform 1 of RPGRIP1 like OS=Gallus gallus OX=9031 GN=RPGRIP1L PE=1 SV=1 CANONICAL=A0A8V0ZHK9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9/entry#A0A8V0ZBY0-1", "sequence": { "sequence": "MSAVGDETVGDMPVRDVGPTLPRVRGLLASARNVKARQAVSQFSRKELEDKYLQLRDENISLKQHANKQEETIKRMATRLIQLVHDKKRNEQVGGGPKRLGRTVKMEGMVEHLQERVRDLEKQNEILRSKLISNKQQIHMPSHRPIQYKFAQPRNSNGLKKASDAAGTPEPTKKGMRLQNLEVRSPPLVLRRCGPNLLEDARAKIRNLSNIRDNVEMIKVRKQLAEKSSALAAMESKFLQLQENQRNFKTNHDVLIAKSEELNVQLKEERSKCLHLEKELQSVAISKRRTEELEERVNDLEREKELLKENCDKLSSSVFSMTREQEWKLKEEQLKLQIAELETAIQSSLADKDEILGKLKVERDKKEKLMEENKDLQSCYLENKQQLDELKDYMKYLTKRCDVDVAELSEALLLIKVRKEQKKNGDLICLEKDDDDIQKVSERSMRKLQLAHAETVQELEKTRSMLIVQHKINKGYQTEIEAVTQKMESLQKDYELKIGKYVDLLDMKAARIKKLEAQLRDVAYGSKRYKFRPEILPANPVNIFDETLHFERREGLFEIHISKVIFSSEAVHAFGDHEPATFCTYAFYDFELQATPVLHGHTLSYDFTSQYLAQIDDSFLHYIQSNSVTLEVHHAYGTDYETVATCQLALHEVLEQNGRIYSTAVLVGINGNIQDFGTVEYWVRLQAPMDQSIGLYKEKSKAQEYITPNFREHESPFQQQILRTAEVSASTSDGDLNELHVTIKCCNRLQSQKKHLQPNSYVVYKFFDFAHHDTRIIPSSSNPQIDDHMCFQVPMTADLDQYLKWESLTFYVFDDSEMGEDGFLGKANVPLIPLACNRSISGTFEVTDSERRVTGAIRVELKWKFAYLSPSGAAVAADLENNIQNEKSMAPKLLSEQEMQPPAFSPSFTSSVTVPIPKPRRHAPQTDKEVSLLNASSVQMRGAVESDMELKNKIETSTGPNALEVKQERPADVKVKETAKGIQQEKEDRSCLSEEQLTGQSSVTSGKETEITEEQEPEAGQDNRHRNDSIESETDSDDCIVTSPISKNIIQATEKIRIEIISLGLTESRIVEDNTIQQLFVECRLYNFIAEETPVSLPKPPCGQRVHYNYSNVIHVDKANNRARREYLKSILQKPSLRTDRLLFTVVSDPPEDEQDLECEDIGFAYVSLREIFEKKRDVIEQDIFVFDSQDDSAVIGKLRVTVEALHALCSVYEECEDDYEA", "length": 1222, "header": "tr|A0A8V0ZBY0-1|A0A8V0ZHK9_CHICK Computationally mapped isoform of RPGRIP1 like OS=Gallus gallus OX=9031 GN=RPGRIP1L PE=1 SV=1 CANONICAL=A0A8V0ZHK9-1" }, "locus": { "chromosome": "11", "start_pos": 4580710, "end_pos": 4522411, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051620.1", "url": "https://www.ensembl.org/id/ENSGALT00010051620.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030787.1", "url": "https://www.ensembl.org/id/ENSGALP00010030787.1" } ] } }, { "isoform_ac": "A0A8V0ZHK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9/entry#A0A8V0ZHK9-1", "sequence": { "sequence": "MSAVGDETVGDMPVRDVGPTLPRVRGLLASARNVKARQAVSQFSRKELEDKYLQLRDENISLKQHANKQEETIKRMATRLIQLVHDKKRNEQVGGGPKRLGRTVKMEGMVEHLQERVRDLEKQNEILRSKLISNKQQIHMPSHRPIQYKFAQPRNSNGLKKASDAAGTPEPTKKGMRLQNLEVRSPPLVLRRCGPNLLEDARAKIRNLETVIDSQRGRIQELEHLSELLGSQLRNKEKEIEESALHLKEQEAARQRDKRSNIRDNVEMIKVRKQLAEKSSALAAMESKFLQLQENQRNFKTNHDVLIAKSEELNVQLKEERSKCLHLEKELQSVAISKRRTEELEERVNDLEREKELLKENCDKLSSSVFSMTREQEWKLKEEQLKLQIAELETAIQSSLADKDEILGKLKVERDKKEKLMEENKDLQSCYLENKQQLDELKDYMKYLTKRCDVDVAELSEALLLIKVRKEQKKNGDLICLEKDDDDIQKVSERSMRKLQLAHAETVQELEKTRSMLIVQHKINKGYQTEIEAVTQKMESLQKDYELKIGKYVDLLDMKAARIKKLEAQLRDVAYGSKRYKFRPEILPANPVNIFDETLHFERREGLFEIHISKVIFSSEAVHAFGDHEPATFCTYAFYDFELQATPVLHGHTLSYDFTSQYLAQIDDSFLHYIQSNSVTLEVHHAYGTDYETVATCQLALHEVLEQNGRIYSTAVLVGINGNIQDFGTVEYWVRLQAPMDQSIGLYKEKSKAQEYITPNFREHESPFQQQILRTAEVSASTSDGDLNELHVTIKCCNRLQSQKKHLQPNSYVVYKFFDFAHHDTRIIPSSSNPQIDDHMCFQVPMTADLDQYLKWESLTFYVFDDSEMGEDGFLGKANVPLIPLACNRSISGTFEVTDSERRVTGAIRVELKWKFAYLSPSGAAVAADLENNIQNEKSMAPKLLSEQEMQPPAFSPSFTSSVTVPIPKPRRHAPQTDKEVSLLNASSVQMRGAVESDMELKNKIETSTGPNALEVKQERPADVKVKETAKGIQQEKEDRSCLSEEQLTGQSSVTSGKETEITEEQEPEAGQDNRHRNDSIESETDSDDCIVTSPISKNIIQATEKIRIEIISLGLTESRIVEDNTIQQLFVECRLYNFIAEETPVSLPKPPCGQRVHYNYSNVIHVDKANNRARREYLKSILQKPSLRTDRLLFTVVSDPPEDEQDLECEDIGFAYVSLREIFEKKRDVIEQDIFVFDSQDDSAVIGKLRVTVEALHALCSVYEECEDDYEA", "length": 1273, "header": "tr|A0A8V0ZHK9-1|A0A8V0ZHK9_CHICK Isoform 1 of RPGRIP1 like OS=Gallus gallus OX=9031 GN=RPGRIP1L PE=1 SV=1 CANONICAL=A0A8V0ZHK9-1" }, "locus": { "chromosome": "11", "start_pos": 4580710, "end_pos": 4522411, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051626.1", "url": "https://www.ensembl.org/id/ENSGALT00010051626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030789.1", "url": "https://www.ensembl.org/id/ENSGALP00010030789.1" } ] } }, { "isoform_ac": "A0A8V0ZPY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9/entry#A0A8V0ZPY4-1", "sequence": { "sequence": "MSAVGDETVGDMPVRDVGPTLPRVRGLLASARNVKARQAVSQFSRKELEDKYLQLRDENISLKQHANKQEETIKRMATRLIQLVHDKKRNEQVGGGPKRLGRTVKMEGMVEHLQERVRDLEKQNEILRSKLISNKQQIHMPSHRPIQYKFAQPRNSNGLKKASDAAGTPEPTKKGMRLQNLEVRSPPLVLRRCGPNLLEDARAKIRNLETVIDSQRGRIQELEHLSELLGSQLRNKEKEIEESALHLKEQEAARQRSNIRDNVEMIKVRKQLAEKSSALAAMESKFLQLQENQRNFKTNHDVLIAKSEELNVQLKEERSKCLHLEKELQSVAISKRRTEELEERVNDLEREKELLKENCDKLSSSVFSMTREQEWKLKEEQLKLQIAELETAIQSSLADKDEILGKLKVERDKKEKLMEENKDLQSCYLENKQQLDELKDYMKYLTKRCDVDVAELSEALLLIKVRKEQKKNGDLICLEKDDDDIQKVSERSMRKLQLAHAETVQELEKTRSMLIVQHKINKGYQTEIEAVTQKMESLQKDYELKIGKYVDLLDMKAARIKKLEAQLRDVAYGSKRYKFRPEILPANPVNIFDETLHFERREGLFEIHISKVIFSSEAVHAFGDHEPATFCTYAFYDFELQATPVLHGHTLSYDFTSQYLAQIDDSFLHYIQSNSVTLEVHHAYGTDYETVATCQLALHEVLEQNGRIYSTAVLVGINGNIQDFGTVEYWVRLQAPMDQSIGLYKEKSKAQEYITPNFREHESPFQQQILRTAEVSASTSDGDLNELHVTIKCCNRLQSQKKHLQPNSYVVYKFFDFAHHDTRIIPSSSNPQIDDHMCFQVPMTADLDQYLKWESLTFYVFDDSEMGEDGFLGKANVPLIPLACNRSISGTFEVTDSERRVTGAIRVELKWKFAYLSPSGAAVAADLENNIQNEKSMAPKLLSEQEMQPPAFSPSFTSSVTVPIPKPRRHAPQTDKEVSLLNASSVQMRGAVESDMELKNKIETSTGPNALEVKQERPADVKVKETAKGIQQEKEDRSCLSEEQLTGQSSVTSGKETEITEEQEPEAGQDNRHRNDSIESETDSDDCIVTSPISKNIIQATEKIRIEIISLGLTESRIVEDNTIQQLFVECRLYNFIAEETPVSLPKPPCGQRVHYNYSNVIHVDKANNRARREYLKSILQKPSLRTDRLLFTVVSDPPEDEQDLECEDIGFAYVSLREIFEKKRDVIEQDIFVFDSQDDSAVIGKLRVTVEALHALCSVYEECEDDYEA", "length": 1270, "header": "tr|A0A8V0ZPY4-1|A0A8V0ZPY4_CHICK Computationally mapped isoform of RPGRIP1 like OS=Gallus gallus OX=9031 GN=RPGRIP1L PE=1 SV=1 CANONICAL=A0A8V0ZHK9-1" }, "locus": { "chromosome": "11", "start_pos": 4580710, "end_pos": 4522411, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051631.1", "url": "https://www.ensembl.org/id/ENSGALT00010051631.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030793.1", "url": "https://www.ensembl.org/id/ENSGALP00010030793.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 20, "start_aa": "Thr", "end_pos": 20, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr20", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:425392", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425392", "resource": "KEGG Pathway" }, { "id": "R-GGA-5610787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610787", "resource": "Reactome", "description": "Hedgehog 'off' state" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZM09-1", "protein_name": "Protein fantom", "gene_name": "RPGRIP1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGPADETAGDLPVKDIGLNLFGMGRLQETSTTRTMKSLQAVSRISREELEDRFLRLHDENILLKQHARKQEDKIKRMATKLIRLVNDKKRYERVGGGPKRLGRDVEMEEMIEQLQEKVHELERQNEVLKNRLISTKQQLQIQGHRHTPYNYVQSRVNTGRRKVNENAAIQECPRKGIKFQDTDVAETLQPMPAAKYGNSLLEEARGEIRNSENVIQSQRCRIEELEDLTELLKTQLRRKENEVELSLLQLREQQATDQRSNIRDNVEMIKLHKQLVEKSNALSVMEGKFIQLQEKQKTLRISHDALMANGDELNKQLKEQRLKCCNLEKQLRSVTFSERRVEELQDRINDLEKERELLKENYDKLYNSAFSAAQEEQWKLKEQQLKVQIAQLETALKSDLTDKTEILDRLKTERDQNEKIIQENRELQLQYLEQKQQLDELKNRMKFYSQESDINADELSEALLLIKDQKSQKNGDLSFLEKVDNKIYNKDLERSMKELQATHAETVQELEKTRNMLIMQHKINKDYQMEVEAVTQKMENLQQDYELKVEQYVHLLDIRAARIQKLEAQLKDIAYGTKQYKFKPEIMPEDSVDAFDETIHLERGENLFEIHINKVTFSSEVLQASGEKEPVTFCTYAFYDFELQTTPIVRGRHPEYNFTSQYLIQVNDLFLQYIQKNTITLEVHQAYSTDYETIAACQLRFHEILEKSGRIFCTASLVGTKGDIPNFGTVEYWFRLRVPMDQAIRLYRERAKALGYITSNFKGPEKMQWLSQQAPNPAQLSSTDSTDGNLNELHITIKCCNHLQSRESHLQPHPYVVYKFFDFADHDTAIIPSSNDPQFDDHMCFPVPMNMDLDRYLKSETLSFYVFDDSDTQENIYIGKVSVPLISLAHDRCISGIFELTDHKKHPAGTIHVILKWKFAYLPPSGAITTEDLGNFIHKEESEVVQRLPPTSSVSTLIVAPKPKPRRLAPKDKRVSFVDITPHQHSETSTPPKDMKEISPEVEHTPEIEISMPTVSHIPKVSQENSIDQLKEKTEKMQQVKDDVSLLSEGQLARKSLTSSEDETEITEELEPGDEEDKSASDSDECIIPVPISKNVRQSSEKIQIEIIALSLNDSRLTADDTIQRLFVECRFYTLPAEETPVSLPKPRSGQWVYYNFSNVIYVDRENNQAKRDILKAILLKQEMPNRSVRFTVVSDPPEDEQDLECEDIGMANIDLADMFREGSDIIEQNIDVLDTRADGGSIGKLKVTVRALDALRSVYEQYRDDLEA", "length": 1270 }, "evidence": [ { "id": "A0A8V0ZHK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZHK9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AB32TJB3-1", "protein_name": "Protein fantom isoform X1", "gene_name": "rpgrip1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFSRADETAADIPVRDTNGAALPDSLLSQNIRERQNVSKLSREELEDKYLRLQDENLTLKQHTCKQEDKIRRMATKLIRLVKDRKQRDGGRDVEMEEMMEELQEKVQELEKQNEGLKRRLLAAKQQLQVQSRRHTPYAHIQSRINTGLRRVPDTHTPVTTSRPHTPKAALRHVEGEISAKPPQSLLPRYGHSLLDEARAEIRNLENVIESQQMQMEELERSAEMMRDQLKRRDREFEESLLQVREQQASGQRLTIKDNVEMIKLQKLLSEKANTLAVLEGRFLQQQESMKTLKASHDAALLKVEDGNRQLKEERLKSLQLETQITSRALEHRHLLELQERIQDLEKERDLLKENCDKLVKSAFDVSQEQKWRTREQQLKLQVAQLETALKSDLADKNQILDKIKAERDVNENLTQENKQLQLRYLEQKQQLEEIKDRMKFFTKESEIDAAELSEALMLIKVRRSQKSGELGFLEKVEEDVKVDVERSLKELQATYAETVQELEKTRNMLIIQHKINKDYQAEVEAVNRMMDDLKLEYELKSEKLAQLLDMRAAKIRKLEAQLKDIAYGTKTHVFRPDETSDDVTDEFEGTVQLTRGENLLEIHLGKGQFSPEAVESLKDKDPSTFCTYAFYDFELQSTPVVHGGRPDYSFSSQYLVRVDDLFLNYLHTSSITVEIQLAEGLSFRTVAAGQIRLNQLLERDGKVFSTIQLVGVSDEIQVFGSLEYWLKLKVPMDQAIRLYKERVKALGFLKTSLRDSKAFSVPAPSSSSLMNGDLNELSISIHSCCNLKPKGPHTQPSPYIVYKLYDFPDHDTPIIPCTTEPQFEDHMVFPMTMNSNLDAFLRSEALVVYVFDDLDVENQLYLGKARVPLVSLAHDKTITGLFELTDPAGLPSGQINVTLKWSFTYLPPSSTVFSTQQTPERQTSHEKDKIETETHMMTEELQPSLSETPMPRPRQRTLPKSTIKRVSFVDVTELEKQMEQHTPTDEEDDDDDDDEEQRAPVTPASKTVIRLDAGSSSAVSEEEEDEEESQFSEGQLITGSSQSEESEISEQLQTDAQAEDDDDDDSDDCIVPAHSTQQKKQPSECIRVEIVSLSLKPGSRVAEDSRIVRLFVEYAFLGLQSVETPLSLKKPLPGRSVSYNFSNVIHVDMENNQARRQTLRAVLEGRNRQLEHIKFTVVSDPPEEAEQEEECEDVGVAFLRLLDIMDRRRDMKDVSVNIVDVQDSSAIIGHLVVTVEALEALMSIMKDPERDRPLTTLA", "length": 1258 }, "evidence": [ { "id": "A0A8V0ZHK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZHK9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0L5P7-1", "protein_name": "Protein fantom", "gene_name": "Rpgrip1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGPSDETAGDLPVKDTGLHLFGIGGLQETSTARTVKARQAVSRVSREELEDRFLRLHDENILLKQHARKQEDKIKRMATKLIRLVNDKKRYERVGGGPKRLGRDVEMEEMIEQLQEKVHELERQNEVLKNRLISAKQQLQVQGHRQTSYSRVQARTNTGRRKASTTAGLQECLGKGIKVQNVDEAETVQPTLTKYSSGLLEEARGEIRNLENVIQSQRGQIEELEHLAEILKTQLKRKENEIELSLLQLREQQATDQRSNIRDNVEMIKLHKQLVEKSNALSVIEGKFIQLQEKQRTLRISHDALMANGDELNMQLKEQRLKCCSLEKQLHSVRFSERRVEELQDRINDLEKERELLKENYDKLYNSAFSAAHEEQWKLKEQQMKVQIAQLETALKSDLTDKAEVLDQLKTERGPLINQNEKLVQENRDLQLQCLQQKQQLHELQNRMKFFNQESDINVDDLSEALLLIKAQKEQKNGDLSFLEKVDSKINKDLDRSMKELQATHAETVQELEKTRNMLIMQHKINKDYQMEVETVTQKMENLQQDHELKVEQYVHLLDVRAARIQKLEAQLKDIAYGTKQYKFKPEIMPDDSVDEFDETIHLERGENLFEIHINKVAFASDVLRASGDKELLTFCTYAFYDFELQTTPIVRGPCPEYNFTSQYLVHVNDLFLQYIQKNTVTLELHQAYSTDYETVAACQLRFHEILEKSGRIFCTTSLVGTKGDIPNFGTVEYWFRLRVPMDQAIRLYRERAKALGYITSNFKKPEKMQLLSQQAATTAQISSPESTDGNLNELHITVRCCTNLQSRARHLQPHAYVVYKFFDFPDHDTAIIPSSNDPQFDDYMCFPVPMNMDLDRYLKSESLSFYVFDDSDIQENIYIGKVNVPLISLAHDRCISGIFELMDKDKHAAGTIQVILKWKFTYLPPSGSIPTEDLGRFVGREEPEAIQRRPPTSSGTEAVVTPKPKPRQRLTFVDKKVSFVDTMPHPSPEASPPPKDIKHNSPEVGPETENSMPAVACPSKESSVAKVEENMGKTQQGKEDDISFLSEGQLASQSVASSEDETEITEELEPEDEDRSASDSDDCIIPSSVSTDTKKPSEEIRIEIIALSLNDSQITREDTVQRLFIECRFYSLPAEETPMSLPKPKSGQWVYYNYTHVLYLDKENNPAVRDVLKAVLQRRELPHRSVRFTVVSDPPEDEQDLECEDIGVAHLDLVDVFQKGRDIIEQDIDVLDARTDGGSIGKLKVTVEALHALRSVYEQYRKDLEA", "length": 1268 }, "evidence": [ { "id": "A0A8V0ZHK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZHK9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H0R2-1", "protein_name": "Protein fantom", "gene_name": "Rpgrip1l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGPSDETAGDLPVKDIGLNLFGVGGLQETSTARTMKTRQAVSRVSREELEDRFLRLHDENILLKQHARKQEDKIKRMATKLIRLVNDKKRYERVGGGPKRLGRDVEMEEMIEQLQEKVHELERQNEVLKNRLISAKQQLQIQGHRQTLHSRVQARINTGRRKVSANTSLQECPRKGLRLQTVDEAETAQPTLTKYGNSLLEEARGEIRNLENVIQSQRGQIEELEHLAEILKTQLRRKESEIELSLLQLREQQATDQRSNIRDNVEMIKLHKQLMEKSNALSVIEGKFIQLQEKQRTLRISHDALMANGDELNKQLKEQRLKCCSLEKQLHSARFSERRVEELQDRINDLEKERELLKENYDKLYNSAFSAAHEEQWKLKEQQMKVQIAQLETALKSDLTDKTEVLDKLKTERDQNEKLVQENRELQLQCLQQRQQLDELKSRMRFFNQESDINPDDLSEALLLIKSQKEQKNGDLSFLEKVDSKINKDLEHSIKELQATHAETVQELEKTRNMLIMQHKINKDYQMEVEAVTQKMENLQQDYELKVEQYVHLLDIRAARIQKLEAQLKDIAYGTKQYKFKPEIMPDDSVDEFDETIHLERGENLFEIHINKVTFSSEVLQASGDKEPVTFCTYAFYDFELQTTPIVRGLCPEYNFTSQYLVHVNDLFLQYIQKNTVTLELHQAYSTDYETIAACQLRFHEILEKSGRIFCTASLVGTKGDIPNFGTVEYWFRLRVPMDQAIRLYRERAKALGYITSNFKKPEKMQLLSQQAPTTAQISSTDSTDGNLNELHITVRCCSNLQSRASHLQPHAYVVYKFFDFPDHDTAIIPSSNDPQFDDHMCFPVPMNLDLDRYLKSESLGFYVFDDSDTQENIYIGKVNVPLISLAHDRCISGIFELMDNEKHSAGTIQVILKWKFTYLPPSGSITTEDLGKFICREEPEVVQKLPPTSSGITSVVAPKPKPRQRLTLVDKKVSFVDAMPHLSPTSPPPPKDTKDNSPKMEHTPETVTSMPAGTFTSKESSVAEVKENIEKMQQGKEDDISFLSEGQLASQSVASSEDETEITEELEPDEDRSTSDSDDCIVPGSVSEDTKESSEEIRIEIIALSLNDSRITRDDTIQQLFIECRFYSLPAEETPMSLPKPKNGQWVYYNYSNVIYLDKENNPVERDILKAVLQRQELTHRSVRFTVVSDPPEDEQHLECEDIGIAHVDLMDVFQKGRDIIEQDIDVFDARADGGSIGKLKVTVEALHALQSVYEQYGEDSEA", "length": 1265 }, "evidence": [ { "id": "A0A8V0ZHK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZHK9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q68CZ1-1", "protein_name": "Protein fantom", "gene_name": "RPGRIP1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGPTDETAGDLPVKDTGLNLFGMGGLQETSTTRTMKSRQAVSRVSREELEDRFLRLHDENILLKQHARKQEDKIKRMATKLIRLVNDKKRYERVGGGPKRLGRDVEMEEMIEQLQEKVHELEKQNETLKNRLISAKQQLQTQGYRQTPYNNVQSRINTGRRKANENAGLQECPRKGIKFQDADVAETPHPMFTKYGNSLLEEARGEIRNLENVIQSQRGQIEELEHLAEILKTQLRRKENEIELSLLQLREQQATDQRSNIRDNVEMIKLHKQLVEKSNALSAMEGKFIQLQEKQRTLRISHDALMANGDELNMQLKEQRLKCCSLEKQLHSMKFSERRIEELQDRINDLEKERELLKENYDKLYDSAFSAAHEEQWKLKEQQLKVQIAQLETALKSDLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIKLYNQENDINADELSEALLLIKAQKEQKNGDLSFLVKVDSEINKDLERSMRELQATHAETVQELEKTRNMLIMQHKINKDYQMEVEAVTRKMENLQQDYELKVEQYVHLLDIRAARIHKLEAQLKDIAYGTKQYKFKPEIMPDDSVDEFDETIHLERGENLFEIHINKVTFSSEVLQASGDKEPVTFCTYAFYDFELQTTPVVRGLHPEYNFTSQYLVHVNDLFLQYIQKNTITLEVHQAYSTEYETIAACQLKFHEILEKSGRIFCTASLIGTKGDIPNFGTVEYWFRLRVPMDQAIRLYRERAKALGYITSNFKGPEHMQSLSQQAPKTAQLSSTDSTDGNLNELHITIRCCNHLQSRASHLQPHPYVVYKFFDFADHDTAIIPSSNDPQFDDHMYFPVPMNMDLDRYLKSESLSFYVFDDSDTQENIYIGKVNVPLISLAHDRCISGIFELTDHQKHPAGTIHVILKWKFAYLPPSGSITTEDLGNFIRSEEPEVVQRLPPASSVSTLVLAPRPKPRQRLTPVDKKVSFVDIMPHQSDETSPPPEDRKEISPEVEHIPEIEINMLTVPHVPKVSQEGSVDEVKENTEKMQQGKDDVSLLSEGQLAEQSLASSEDETEITEDLEPEVEEDMSASDSDDCIIPGPISKNIKQSLALSPGLGCSSAISAHCNFRLPGSSDFPASASQVDGITGACHHTQPSEKIRIEIIALSLNDSQVTMDDTIQRLFVECRFYSLPAEETPVSLPKPKSGQWVYYNYSNVIYVDKENNKAKRDILKAILQKQEMPNRSLRFTVVSDPPEDEQDLECEDIGVAHVDLADMFQEGRDLIEQNIDVFDARADGEGIGKLRVTVEALHALQSVYKQYRDDLEA", "length": 1315 }, "evidence": [ { "id": "A0A8V0ZHK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZHK9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CG73-1", "protein_name": "Protein fantom", "gene_name": "Rpgrip1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGPSDETAGDLPVKDTGLNLFGVGGLQETSTARTVKTRQAVSRVSREELEDRFLRLHDENILLKQHARKQEDKIKRMATKLIRLVNDKKRYERVGGGPKRLGRDVEMEEMIEQLQEKVHELERQNEVLKNRLISAKQQLQVQGHRQTSYSRVQARVNTGRRRASASAGSQECPGKGLRFQNVDEAETVQPTLTKYSNSLLEEARGEIRNLENVIQSQRGQIEELEHLAEILKTQLKRKENEIELSLLQLREQQATDQRSNIRDNVETIKLHKQLVEKSNALSVIEGKFIQLQEKQRTLRISHDALMANGDELNKQLKEQRLKCCSLEKQLHSVRFSERRVEELQDRINDLEKERELLKENYDKLYNSAFSAAHEEQWKLKEQQMKVQIAQLETALKSDLTDKTEVLDKLKTERDQNEKLVQENRDLQLQCLQQKQRLHELQSRLKFFNQESDINADDLSEALLLIKAQKEQKNGDLSFLEKVDSKINKDLDRSMKELQATHAETVQELEKTRNMLIMQHKINKDYQMEVETVTQKMENLQQDYELKVEQYVHLLDIRAARIQKLEAQLKDIAYGTKQYKFKPEIMPDDSVDEFDETIHLERGENLFEIHINKVTFSSEVLRASGDKELVTFCTYAFYDFELQTTPIVRGLYPEYNFTSQYLVHVNDLFLQYIQKNTVTLELHQAHSTDYETIAACQLRFHEILEKSGRIFCTTSLVGTKGDIPNFGTVEYWFRLRVPMDQAIRLYRERAKALGYITSNFKKPEKMQLSSQQAATTAQISPAESTDGNLNELHVTVKCCTGLQSRASYLQPHAYVVYKFFDFPDHDTAIVPSSNDPQFDDHMCFPVPMNMDLDRYLKSESLSFYVFDDSDTQENIYMGKVNVPLISLAHDKCISGIFELMDKEKHAAGTIQVILKWKFTYLPPSGSITTEDLGKFVCREEPEAVQRLPPKSSDVTSVVAPKPKPRQRLTFVDKKVSFADTISHPSPETSPPPKDIKDSSPEVGPKPENGLSAVAYPSKESGVAKVEENVGEMQQGKEDDISFLSEGQLASGSVASSEDETEITEELEPEDEDRSASDSDDCIIPSSVSTNTKQPSEEIRIEIIALNLNDSQITREDTIQRLFIECRFYSLPAEETPMSLPKPQSGQWVYYNYSNVIYLDKENNPAVRDILKAILQRRELPHRSVRFTVVSDPPEDEQDLECEDIGVAHVDLADLFQKGRDIIEQDIDVLDARTDGGTIGKLKVTVEALHALRSVYEQNRKDLEA", "length": 1264 }, "evidence": [ { "id": "A0A8V0ZHK9", "url": "https://omabrowser.org/oma/group/A0A8V0ZHK9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of G protein-coupled receptor signaling pathway", "id": "GO:0045744", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045744", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" }, { "name": "retinal rod cell development", "id": "GO:0046548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046548", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" }, { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "thromboxane A2 receptor binding", "id": "GO:0031870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031870", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1078, "end_pos": 1080, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1160, "end_pos": 1162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" }, { "start_pos": 985, "end_pos": 987, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZHK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHK9" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 774, "end_pos": 895, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 20 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1078, "end_pos": 1080 }, { "start_pos": 1160, "end_pos": 1162 }, { "start_pos": 59, "end_pos": 61 }, { "start_pos": 888, "end_pos": 890 }, { "start_pos": 985, "end_pos": 987 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZHU3-1", "uniprot_ac": "A0A8V0ZHU3", "uniprot_id": "A0A8V0ZHU3_CHICK", "mass": { "chemical_mass": 51312.0, "monoisotopic_mass": 51312.0 }, "refseq": { "ac": "NP_001006299", "name": "WD repeat-containing protein WRAP73", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006299" }, "gene_names": [ { "name": "WRAP73", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3" } ] }, { "name": "WDR8", "type": "synonym", "evidence": [ { "id": "NP_001006299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006299" } ] }, { "name": "WRAP73", "type": "synonym", "evidence": [ { "id": "NP_001006299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006299" } ] } ], "protein_names": [ { "name": "WD repeat containing, antisense to TP73", "type": "synonym", "evidence": [ { "id": "A0A8V0ZHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3/entry#names_and_taxonomy" } ] }, { "name": "WD repeat domain 8", "type": "synonym", "evidence": [ { "id": "NP_001006299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006299" } ] }, { "name": "WD repeat-containing protein 8", "type": "synonym", "evidence": [ { "id": "NP_001006299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006299" } ] }, { "name": "WD repeat-containing protein WRAP73", "type": "synonym", "evidence": [ { "id": "NP_001006299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006299" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720648.1, HAEL01007434.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000329.1. On Dec 3, 2021 this sequence version replaced NP_001006299.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001006299", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006299" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WRAP73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3", "locus": { "chromosome": "21", "start_pos": 982742, "end_pos": 968354, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021361", "url": "https://www.ensembl.org/id/ENSGALG00010021361" } ] } } ], "crossref": [ { "id": "A0A8V0ZHU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "419383", "url": "https://www.ncbi.nlm.nih.gov/gene/419383", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419383", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419383", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CWHLNGD", "url": "https://omabrowser.org/oma/group/CWHLNGD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC62", "url": "https://www.orthodb.org/?gene=A0A8V0ZC62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHT8", "url": "https://www.orthodb.org/?gene=A0A8V0ZHT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHU3", "url": "https://www.orthodb.org/?gene=A0A8V0ZHU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJB0", "url": "https://www.orthodb.org/?gene=A0A8V0ZJB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJE1", "url": "https://www.orthodb.org/?gene=A0A8V0ZJE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16220:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16220:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006299", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006299", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFSELFKLSGLLGRFSPDGKCLASCVQYRLIIRDVNTLQILQLYTCLDQIQYIEWSSDSLFILCAMYKRGIVQVWSLEQPDWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKSVSYIKYPKACQQGIAFTKDGRYMAVAERRDCKDFVSLFVCSNWQLLRHFDTETQDLFGIEWAPNGCILAVWDTCLEYKILLYSLDGRLLSTYQAYEWSLGIKSIAWSPSSQFLAIGSYDEKVRILNHVTWKKITEFEHPATVTNTKTIVYKEVEKSPSVETERFSFPPTRALASSVFSTQSKYDISQVPVSFQYIKPVADRANPKMGIGMLAFSPDNCFLATRNDNIPNAVWIWDIQKLKLFVVLEQLCAIQSFQWDPRQPRLAVCTGNSKVYLWSPAGCVSVQVPTEGDFQIVSLCWHPSGDSMALLSKDNFCVCYLEREEVK", "length": 449, "header": "tr|A0A8V0ZHU3-1|A0A8V0ZHU3_CHICK Isoform 1 of WD repeat containing, antisense to TP73 OS=Gallus gallus OX=9031 GN=WRAP73 PE=4 SV=1 CANONICAL=A0A8V0ZHU3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZC62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3/entry#A0A8V0ZC62-1", "sequence": { "sequence": "MDFSELFKLSGLLGRFSPDGKCLASCVQYRLIIRDVNTLQILQLYTCLDQIQYIEWSSDSLFILCAMYKRGIVQVWSLEQPDWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKSVSYIKYPKACQQGIAFTKDGRYMAVAERRDCKDFVSLFVCSNWQLLRHFDTETQDLFGIEWAPNGCILAVWDTCLEYKILLYSLDGRLLSTYQAYEWSLGIKSIAWSPSSQFLAIGSYDEKVRILNHVTWKKITEFEHPATVTNTKTMTFPRCQSLSSTSNLLLIGLIPKWGLGCWRSVQITVSWQPEMVSSFCLPLKEKPFCYMCITLGLALFSNNNLLFIFLHIYMKPFTVLENEAHSSFLLHFQHLSLGRQSSSQPVVVGLLISTDGHGINTQVFPLTGLRAVYVRMQKLWFRGRAH", "length": 425, "header": "tr|A0A8V0ZC62-1|A0A8V0ZHU3_CHICK Computationally mapped isoform of WD repeat containing, antisense to TP73 OS=Gallus gallus OX=9031 GN=WRAP73 PE=4 SV=1 CANONICAL=A0A8V0ZHU3-1" }, "locus": { "chromosome": "21", "start_pos": 980173, "end_pos": 968450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051748.1", "url": "https://www.ensembl.org/id/ENSGALT00010051748.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030867.1", "url": "https://www.ensembl.org/id/ENSGALP00010030867.1" } ] } }, { "isoform_ac": "A0A8V0ZHT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3/entry#A0A8V0ZHT8-1", "sequence": { "sequence": "MDFSELFKLSGLLGRFSPDGKCLASCVQYRLIIRDVNTLQILQLYTCLDQIQYIEWSSDSLFILCAMYKRGIVQVWSLEQPDWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKSVSYIKYPKACQQGIAFTKDGRYMAVAERRDCKDFVSLFVCSNWQLLRHFDTETQDLFGIEWAPNGCILAVWDTCLEYKILLYSLDGRLLSTYQAYEWSLGIKSIAWSPSSQFLAIGSYDEKIVYKEVEKSPSVETERFSFPPTRALASSVFSTQSKYDISQVPVSFQYIKPVADRANPKMGIGMLAFSPDNCFLATRNDNIPNAVWIWDIQKLKLFVVLEQLCAIQSFQWDPRQPRLAVCTGNSKVYLWSPAGCVSVQVPTEGDFQIVSLCWHPSGDSMALLSKDNFCVCYLEREEVK", "length": 423, "header": "tr|A0A8V0ZHT8-1|A0A8V0ZHT8_CHICK Computationally mapped isoform of WD repeat containing, antisense to TP73 OS=Gallus gallus OX=9031 GN=WRAP73 PE=4 SV=1 CANONICAL=A0A8V0ZHU3-1" }, "locus": { "chromosome": "21", "start_pos": 980918, "end_pos": 968450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051757.1", "url": "https://www.ensembl.org/id/ENSGALT00010051757.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030874.1", "url": "https://www.ensembl.org/id/ENSGALP00010030874.1" } ] } }, { "isoform_ac": "A0A8V0ZHU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3/entry#A0A8V0ZHU3-1", "sequence": { "sequence": "MDFSELFKLSGLLGRFSPDGKCLASCVQYRLIIRDVNTLQILQLYTCLDQIQYIEWSSDSLFILCAMYKRGIVQVWSLEQPDWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKSVSYIKYPKACQQGIAFTKDGRYMAVAERRDCKDFVSLFVCSNWQLLRHFDTETQDLFGIEWAPNGCILAVWDTCLEYKILLYSLDGRLLSTYQAYEWSLGIKSIAWSPSSQFLAIGSYDEKVRILNHVTWKKITEFEHPATVTNTKTIVYKEVEKSPSVETERFSFPPTRALASSVFSTQSKYDISQVPVSFQYIKPVADRANPKMGIGMLAFSPDNCFLATRNDNIPNAVWIWDIQKLKLFVVLEQLCAIQSFQWDPRQPRLAVCTGNSKVYLWSPAGCVSVQVPTEGDFQIVSLCWHPSGDSMALLSKDNFCVCYLEREEVK", "length": 449, "header": "tr|A0A8V0ZHU3-1|A0A8V0ZHU3_CHICK Isoform 1 of WD repeat containing, antisense to TP73 OS=Gallus gallus OX=9031 GN=WRAP73 PE=4 SV=1 CANONICAL=A0A8V0ZHU3-1" }, "locus": { "chromosome": "21", "start_pos": 980918, "end_pos": 968450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051765.1", "url": "https://www.ensembl.org/id/ENSGALT00010051765.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030879.1", "url": "https://www.ensembl.org/id/ENSGALP00010030879.1" } ] } }, { "isoform_ac": "A0A8V0ZJB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3/entry#A0A8V0ZJB0-1", "sequence": { "sequence": "MDFSELFKLSGLLGRFSPDGKCLASCVQYRLIIRDVNTLQILQLYTCLDQIQYIEWSSDSLFILCAMYKRGIVQVWSLEQPDWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKSVSYIKYPKACQQGIAFTKDGRYMAVAERRDCKDFVSLFVCSNWQLLRYKILLYSLDGRLLSTYQAYEWSLGIKSIAWSPSSQFLAIGSYDEKVRILNHVTWKKITEFEHPATVTNTKTIVYKEVEKSPSVETERFSFPPTRALASSVFSTQSKYDISQVPVSFQYIKPVADRANPKMGIGMLAFSPDNCFLATRNDNIPNAVWIWDIQKLKLFVVLEQLCAIQSFQWDPRQPRLAVCTGNSKVYLWSPAGCVSVQVPTEGDFQIVSLCWHPSGDSMALLSKDNFCVCYLEREEVK", "length": 420, "header": "tr|A0A8V0ZJB0-1|A0A8V0ZJB0_CHICK Computationally mapped isoform of WD repeat containing, antisense to TP73 OS=Gallus gallus OX=9031 GN=WRAP73 PE=4 SV=1 CANONICAL=A0A8V0ZHU3-1" }, "locus": { "chromosome": "21", "start_pos": 980918, "end_pos": 968450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051769.1", "url": "https://www.ensembl.org/id/ENSGALT00010051769.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030881.1", "url": "https://www.ensembl.org/id/ENSGALP00010030881.1" } ] } }, { "isoform_ac": "A0A8V0ZJE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3/entry#A0A8V0ZJE1-1", "sequence": { "sequence": "MDFSELFKLSGLLGRFSPDGKCLASCVQYRLIIRDVNTLQILQLYTCLDQIQYIEWSSDSLFILCAMYKRGIVQVWSLEQPDWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKSVSYIKYPKACQQGIAFTKDGRYMAVAERRDCKDFVSLFVCSNWQLLRHFDTETQDLFGIEWAPNGCILAVWDTCLEYKILLYSLDGRLLSTYQAYEWSLGIKSIAWSPSSQFLAIGSYDEKVRILNHVTWKKITEFEHPATVTNTKTIVYKEVEKSPSVETERFSFPPTRALASSVFSTQSKYDISQVPVSFQYIKPVADRANPKMGIGMLAFSPDNCFLATRNDNIPNAVWIWDIQKLKLFVVLEQLCAIQSFQWDPRQPRLAVCTGNSKVYLWSPAGCVSVQVPTEGDFQIVSLCWHPSGDSMALLKIEAVKMNEVGDIYLY", "length": 449, "header": "tr|A0A8V0ZJE1-1|A0A8V0ZJE1_CHICK Computationally mapped isoform of WD repeat containing, antisense to TP73 OS=Gallus gallus OX=9031 GN=WRAP73 PE=4 SV=1 CANONICAL=A0A8V0ZHU3-1" }, "locus": { "chromosome": "21", "start_pos": 981335, "end_pos": 968450, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051776.1", "url": "https://www.ensembl.org/id/ENSGALT00010051776.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030885.1", "url": "https://www.ensembl.org/id/ENSGALP00010030885.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419383", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419383", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BI45-1", "protein_name": "WD repeat containing, antisense to TP73", "gene_name": "WRAP73", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNFSEVFKLSNLLCKFSPDGKYLASCVQYRLVVRDASTLQILQLYTCLDQIQHIEWSADSLFILCALYRRGLVQVWSLEQPDWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKSVSYIKYPKACQQGITFTRDGRYLALAERRDCRDHVSIFVCSDWQLLRHFETDTQDLAGIEWAPNGCVLAAWDTCLEYKILLYSLDGRLLSTYCAYEWSLGIKSVAWSPSSQFLAVGSYDGKVRVLNHVTWKLLAELGHPAAVSSPSTVVYREAEKSPPLALGRLAFPPPRAPAGPRATTESKYEIATVPASLRTLKPTADRANPRMGIGALAFSLDNYFLATRSDSIPSAVWIWDVRKLRLFVVLEQLSAVRSFRWDPRQPRLAICTGGSQVYLWSPAGCVSVQVPGEGDFQVLSLCWHPSGDSLALLSKDHFCLCFLEAEEGVGTALGQQDDHT", "length": 460 }, "evidence": [ { "id": "A0A8V0ZHU3", "url": "https://omabrowser.org/oma/group/A0A8V0ZHU3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B8A4V4-1", "protein_name": "WD repeat-containing protein WRAP73", "gene_name": "wrap73", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNFSEVFKQSNQLCKVSPDGKYLATCVQYRLVVRDIGTLQIVHLYTCLDQVMHMEWSSDSLFILCAMYKRGLVQVWSLEQPDWHCKIDEGSIGLVSSRWSPDGRHILNTTEFNLRITVWSLCTKSVSYIKYPKACQKGMDFTADGRYMALAERRDCKDYISVFVCDDWHLLRHFESETQDLAGLEWSPNGCVLAVWDNCLEYKILLYSLDGRLLSFYSAYEWSLGIKSVAWSPSSQFLAIGSYDEKVRILNHITWKKITEFEHPATITNSKAVVFKEVEKRPVVSEDLSIRQLTVDNALFSTQSKYEITQLPVQVPVVKPDPERANPKIGISAVAFSADNRYLATKNDNMPQSLWVWDMQKFSLLAVLEQTAPVRCFVWDPHLPRLALCTGNTKLYMWSPAGCISVTVPVEGFQVQSLFWHCTGSSLVLLSKDQLCLCYTDAEEQK", "length": 446 }, "evidence": [ { "id": "A0A8V0ZHU3", "url": "https://omabrowser.org/oma/group/A0A8V0ZHU3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9JM98-1", "protein_name": "WD repeat-containing protein WRAP73", "gene_name": "Wrap73", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFSESFKLSGLLCRFSPDGKYLASCVQYRLVIRDVTTLQILQLYTCLDQIQHIEWSADSLFILCAMYRRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKSVSYIKYPKACQQGLTFTRDGRYLALAERRDCRDYVSIFVCSDWQLLRHFDTDTQDLTGIEWAPNGCVLAAWDTCLEYKVLLYSLDGRLLSAYCAYEWSLGIKSVAWSPSSQFLAIGSYDGKVRLLNHVTWKMITEFGHPATINNPKTVVYKEAEKSPLLGLGHLSFPPPRAMAGALSTSESKYEIASGPVSLQTLKPVADRANPRMGVGMLAFSSDSYFLASRNDNVPNAVWIWDIQKLKLFVVLEHMSPVRSFQWDPQQPRLAICTGGSKVYLWSPAGCVSVQVPGEGDFPVLGLCWHLSGDSLALLSKDHFCLCFLETKERVGTAYEQRDGMPRT", "length": 462 }, "evidence": [ { "id": "A0A8V0ZHU3", "url": "https://omabrowser.org/oma/group/A0A8V0ZHU3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2S5-1", "protein_name": "WD repeat-containing protein WRAP73", "gene_name": "WRAP73", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFSEVFKLSSLLCKFSPDGKYLASCVQYRLVVRDVNTLQILQLYTCLDQIQHIEWSADSLFILCAMYKRGLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRITVWSLCTKSVSYIKYPKACLQGITFTRDGRYMALAERRDCKDYVSIFVCSDWQLLRHFDTDTQDLTGIEWAPNGCVLAVWDTCLEYKILLYSLDGRLLSTYSAYEWSLGIKSVAWSPSSQFLAVGSYDGKVRILNHVTWKMITEFGHPAAINDPKIVVYKEAEKSPQLGLGCLSFPPPRAGAGPLPSSESKYEIASVPVSLQTLKPVTDRANPKIGIGMLAFSPDSYFLATRNDNIPNAVWVWDIQKLRLFAVLEQLSPVRAFQWDPQQPRLAICTGGSRLYLWSPAGCMSVQVPGEGDFAVLSLCWHLSGDSMALLSKDHFCLCFLETEAVVGTACRQLGGHT", "length": 460 }, "evidence": [ { "id": "A0A8V0ZHU3", "url": "https://omabrowser.org/oma/group/A0A8V0ZHU3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3" } ], "pmid": "" }, { "name": "MWP complex", "id": "GO:1990811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of non-motile cilium assembly", "id": "GO:1902857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3" } ], "pmid": "" }, { "name": "microtubule anchoring at mitotic spindle pole body", "id": "GO:1990810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990810", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZI42-1", "uniprot_ac": "A0A8V0ZI42", "uniprot_id": "A0A8V0ZI42_CHICK", "mass": { "chemical_mass": 118119.0, "monoisotopic_mass": 118119.0 }, "refseq": { "ac": "XP_004942214", "name": "insulin-degrading enzyme isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942214" }, "gene_names": [ { "name": "IDE", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] }, { "name": "IDE", "type": "synonym", "evidence": [ { "id": "XP_004942214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942214" } ] } ], "protein_names": [ { "name": "Insulin-degrading enzyme", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42/entry#names_and_taxonomy" } ] }, { "name": "3.4.24.56", "type": "synonym", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42/entry#names_and_taxonomy" } ] }, { "name": "Insulin protease", "type": "synonym", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42/entry#names_and_taxonomy" } ] }, { "name": "Insulysin", "type": "synonym", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42/entry#names_and_taxonomy" } ] }, { "name": "insulin-degrading enzyme isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004942214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942214" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004942214.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942214" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IDE", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42", "locus": { "chromosome": "6", "start_pos": 21599886, "end_pos": 21544367, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021405", "url": "https://www.ensembl.org/id/ENSGALG00010021405" } ] } } ], "crossref": [ { "id": "A0A8V0ZI42", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZI42", "database": "AlphaFoldDB", "categories": [] }, { "id": "423814", "url": "https://www.ncbi.nlm.nih.gov/gene/423814", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423814", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423814", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WIFDEMK", "url": "https://omabrowser.org/oma/group/WIFDEMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCE5", "url": "https://www.orthodb.org/?gene=A0A8V0ZCE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI42", "url": "https://www.orthodb.org/?gene=A0A8V0ZI42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJH2", "url": "https://www.orthodb.org/?gene=A0A8V0ZJH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJK5", "url": "https://www.orthodb.org/?gene=A0A8V0ZJK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQD7", "url": "https://www.orthodb.org/?gene=A0A8V0ZQD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQF0", "url": "https://www.orthodb.org/?gene=A0A8V0ZQF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43690:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43690:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00675", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00675", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16187", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16187", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-77387", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77387", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9033241", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004942214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942214", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQRLLTELRRALLGCARPWAAPTSQFAPQRGFLGLQKETNNKMNNPAIKRITNEIIKSPEDKREYRGLELANGIKALLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNLMNDAWRLFQLEKATGNPNHPFSKFGTGNKLTLETRPTKEGIDVRQELLKFHSTYYSSNLMAICVLGRESLDELTSLVVKLFSEVENKNVPVPEFPEHPFQEEHLRQLYKVVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKAKGWVYTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRIEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKLGGMLHYYPIEEVLAAEYLLEEFRPDLIEMVLDKLRPENIRVAIVSKSFEGKTDRTEDWYGTQYKQEAISDEVIKKWQNADLNGKFKLPMKNEFIPTNFEILPLEKDATQYPALVKDTAMSKLWFKQDDKFFLPKACLNFEFFSRYIYADPLHCNMTYLFIRLLKDDLKEYTYAARLSGLVYGIASGMNAILLSVKGYNDKQHILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFISQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLKTMEKCIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKDDIIQFYKVLLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDVNLAPAPPLPQPSVIENMTEFKRSLPLFPLVKPHINFMAAKL", "length": 1021, "header": "tr|A0A8V0ZI42-1|A0A8V0ZI42_CHICK Isoform 1 of Insulin-degrading enzyme OS=Gallus gallus OX=9031 GN=IDE PE=1 SV=1 CANONICAL=A0A8V0ZI42-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42/entry#A0A8V0ZCE5-1", "sequence": { "sequence": "MFLHPLLCHCLRYQSISFVFLFVSRYIYADPLHCNMTYLFIRLLKDDLKEYTYAARLSGLVYGIASGMNAILLSVKGYNDKQHILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFISQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLKTMEKCIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKDDIIQFYKVLLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDVNLAPAPPLPQPSVIENMTEFKRSLPLFPLVKPHINFMAAKL", "length": 463, "header": "tr|A0A8V0ZCE5-1|A0A8V0ZI42_CHICK Computationally mapped isoform of Insulin-degrading enzyme OS=Gallus gallus OX=9031 GN=IDE PE=1 SV=1 CANONICAL=A0A8V0ZI42-1" }, "locus": { "chromosome": "6", "start_pos": 21597788, "end_pos": 21580747, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051869.1", "url": "https://www.ensembl.org/id/ENSGALT00010051869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030942.1", "url": "https://www.ensembl.org/id/ENSGALP00010030942.1" } ] } }, { "isoform_ac": "A0A8V0ZI42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42/entry#A0A8V0ZI42-1", "sequence": { "sequence": "MRQRLLTELRRALLGCARPWAAPTSQFAPQRGFLGLQKETNNKMNNPAIKRITNEIIKSPEDKREYRGLELANGIKALLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNLMNDAWRLFQLEKATGNPNHPFSKFGTGNKLTLETRPTKEGIDVRQELLKFHSTYYSSNLMAICVLGRESLDELTSLVVKLFSEVENKNVPVPEFPEHPFQEEHLRQLYKVVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKAKGWVYTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRIEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKLGGMLHYYPIEEVLAAEYLLEEFRPDLIEMVLDKLRPENIRVAIVSKSFEGKTDRTEDWYGTQYKQEAISDEVIKKWQNADLNGKFKLPMKNEFIPTNFEILPLEKDATQYPALVKDTAMSKLWFKQDDKFFLPKACLNFEFFSRYIYADPLHCNMTYLFIRLLKDDLKEYTYAARLSGLVYGIASGMNAILLSVKGYNDKQHILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFISQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLKTMEKCIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKDDIIQFYKVLLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDVNLAPAPPLPQPSVIENMTEFKRSLPLFPLVKPHINFMAAKL", "length": 1021, "header": "tr|A0A8V0ZI42-1|A0A8V0ZI42_CHICK Isoform 1 of Insulin-degrading enzyme OS=Gallus gallus OX=9031 GN=IDE PE=1 SV=1 CANONICAL=A0A8V0ZI42-1" }, "locus": { "chromosome": "6", "start_pos": 21597788, "end_pos": 21544631, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051917.1", "url": "https://www.ensembl.org/id/ENSGALT00010051917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030984.1", "url": "https://www.ensembl.org/id/ENSGALP00010030984.1" } ] } }, { "isoform_ac": "A0A8V0ZJH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42/entry#A0A8V0ZJH2-1", "sequence": { "sequence": "MISKIPSMGCIRYIYADPLHCNMTYLFIRLLKDDLKEYTYAARLSGLVYGIASGMNAILLSVKGYNDKQHILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFISQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLKTMEKCIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKDDIIQFYKVLLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDVNLAPAPPLPQPSVIENMTEFKRSLPLFPLVKPHINFMAAKL", "length": 450, "header": "tr|A0A8V0ZJH2-1|A0A8V0ZJH2_CHICK Computationally mapped isoform of Insulin degrading enzyme OS=Gallus gallus OX=9031 GN=IDE PE=1 SV=1 CANONICAL=A0A8V0ZI42-1" }, "locus": { "chromosome": "6", "start_pos": 21597788, "end_pos": 21580238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051873.1", "url": "https://www.ensembl.org/id/ENSGALT00010051873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030946.1", "url": "https://www.ensembl.org/id/ENSGALP00010030946.1" } ] } }, { "isoform_ac": "A0A8V0ZJK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42/entry#A0A8V0ZJK5-1", "sequence": { "sequence": "MNNPAIKRITNEIIKSPEDKREYRGLELANGIKALLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNLMNDAWRLFQLEKATGNPNHPFSKFGTGNKLTLETRPTKEGIDVRQELLKFHSTYYSSNLMAICVLGRESLDELTSLVVKLFSEVENKNVPVPEFPEHPFQEEHLRQLYKVVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKAKGWVYTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRIEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKLGGMLHYYPIEEVLAAEYLLEEFRPDLIEMVLDKLRPENIRVAIVSKSFEGKTDRTEDWYGTQYKQEAISDEVIKKWQNADLNGKFKLPMKNEFIPTNFEILPLEKDATQYPALVKLSVKGYNDKQHILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFISQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLKTMEKCIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKDDIIQFYKVLLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDVNLAPAPPLPQPSVIENMTEFKRSLPLFPLVKPHINFMAAKL", "length": 902, "header": "tr|A0A8V0ZJK5-1|A0A8V0ZJK5_CHICK Computationally mapped isoform of Insulin degrading enzyme OS=Gallus gallus OX=9031 GN=IDE PE=1 SV=1 CANONICAL=A0A8V0ZI42-1" }, "locus": { "chromosome": "6", "start_pos": 21597788, "end_pos": 21553366, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051908.1", "url": "https://www.ensembl.org/id/ENSGALT00010051908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030976.1", "url": "https://www.ensembl.org/id/ENSGALP00010030976.1" } ] } }, { "isoform_ac": "A0A8V0ZQD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42/entry#A0A8V0ZQD7-1", "sequence": { "sequence": "MLLVRVLWKGVRYSLQKETNNKMNNPAIKRITNEIIKSPEDKREYRGLELANGIKALLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNLMNDAWRLFQLEKATGNPNHPFSKFGTGNKLTLETRPTKEGIDVRQELLKFHSTYYSSNLMAICVLGRESLDELTSLVVKLFSEVENKNVPVPEFPEHPFQEEHLRQLYKVVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKAKGWVYTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRIEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKLGGMLHYYPIEEVLAAEYLLEEFRPDLIEMVLDKLRPENIRVAIVSKSFEGKTDRTEDWYGTQYKQEAISDEVIKKWQNADLNGKFKLPMKNEFIPTNFEILPLEKDATQYPALVKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLNYDLQNTIYGMYLSVKGYNDKQHILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFISQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLKTMEKCIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKDDIIQFYKVLLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDVNLAPAPPLPQPSVIENMTEFKRSLPLFPLVKPHINFMAAKL", "length": 1000, "header": "tr|A0A8V0ZQD7-1|A0A8V0ZQD7_CHICK Computationally mapped isoform of Insulin-degrading enzyme OS=Gallus gallus OX=9031 GN=IDE PE=1 SV=1 CANONICAL=A0A8V0ZI42-1" }, "locus": { "chromosome": "6", "start_pos": 21597788, "end_pos": 21552434, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051882.1", "url": "https://www.ensembl.org/id/ENSGALT00010051882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030953.1", "url": "https://www.ensembl.org/id/ENSGALP00010030953.1" } ] } }, { "isoform_ac": "A0A8V0ZQF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42/entry#A0A8V0ZQF0-1", "sequence": { "sequence": "MNNPAIKRITNEIIKSPEDKREYRGLELANGIKALLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNLMNDAWRLFQLEKATGNPNHPFSKFGTGNKLTLETRPTKEGIDVRQELLKFHSTYYSSNLMAICVLGRESLDELTSLVVKLFSEVENKNVPVPEFPEHPFQEEHLRQLYKVVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKAKGWVYTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRIEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKLGGMLHYYPIEEVLAAEYLLEEFRPDLIEMVLDKLRPENIRVAIVSKSFEGKTDRTEDWYGTQYKQEAISDEVIKKWQNADLNGKFKLPMKNEFIPTNFEILPLEKDATQYPALVKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLNYDLQNTIYGMYLSVKGYNDKQHILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFISQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLKTMEKCIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKDDIIQFYKVLLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDVNLAPAPPLPQPSVIENMTEFKRSLPLFPLVKPHINFMAAKL", "length": 978, "header": "tr|A0A8V0ZQF0-1|A0A8V0ZQF0_CHICK Computationally mapped isoform of Insulin-degrading enzyme OS=Gallus gallus OX=9031 GN=IDE PE=1 SV=1 CANONICAL=A0A8V0ZI42-1" }, "locus": { "chromosome": "6", "start_pos": 21597788, "end_pos": 21553366, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051895.1", "url": "https://www.ensembl.org/id/ENSGALT00010051895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030963.1", "url": "https://www.ensembl.org/id/ENSGALP00010030963.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:423814", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423814", "resource": "KEGG Pathway" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-GGA-77387", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-77387", "resource": "Reactome", "description": "Insulin receptor recycling" }, { "id": "R-GGA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IL71-1", "protein_name": "Insulin-degrading enzyme", "gene_name": "ide", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MILSTVFGRSIRRVSTLSIRMSDPAVKRVVSDIIRSPEDKREYRGLEFTNGLKAILISDPTTDKSSAALDVHMGSLSDPENISGLAHFCEHMLFLGTEKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLQGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNLMNDAWRLFQLEKATGNPKHPFSKFGTGNKLTLETRPSQQGIDIREELLKFHSTYYSSNLMGLCVLGRETLDELTSMVVKLFGEVENKNVPVPEFPTHPFQEEHLRQFYKVVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIIFHMFQYIQKLRTEGPQEWVFQECKDLNTVAFRFKDKERPRGYTSKVAGLLHYYPLEEILAAEYLLEEFRPDLIEMVLDKLRPENVRVAVVSKSFEGQTDRTEEWYGTQYKQEAITDEAIKKWDNADLNGKFKLPMKNEFIPTNFEIYPLEKDSPSAPTLIKDTAMSKVWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTVYGMYLSVKGYNDKQHILLKKIIEKMATFEIDEKRFDIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELRDALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQSALEMMQMLEDTLIEHAHTKPLLPSQLIRYREVQVPDGGWYVYQQRNEVHNNCGIEIYYQTDMQNTHENMLLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGVQGLRFIIQSEKAPHYLESRVEAFLKTMEKSVEEMGDEAFQKHIQALAIRRLDKPKKLAAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKEHIMQFYRDLLAIDAPRRHKVSVHVLSREMDSCPLVGEFPAQNDVNLAPAPSLPQPSLVQDMTEFKRSLPLFPLTKPHINFMAAKL", "length": 998 }, "evidence": [ { "id": "A0A8V0ZI42", "url": "https://omabrowser.org/oma/group/A0A8V0ZI42/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A287BBS8-1", "protein_name": "Insulin-degrading enzyme", "gene_name": "IDE", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRYRLAWLLHPALPSTFRSVLGARLPPLERLCGFQKKTYSKMNNSAIKRLGNHIIKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPNHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLRQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILSLEKEATPYPSLIKDTAMSKLWFKQDDKFFLPKACLNFEFFSRYIYADPLHCNMTYLFIRLLKDDLKEYTYAARLSGLSYGIASGMNAILLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLVTMEKSIEDMAEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNIEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL", "length": 1019 }, "evidence": [ { "id": "A0A8V0ZI42", "url": "https://omabrowser.org/oma/group/A0A8V0ZI42/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O22941-1", "protein_name": "Insulin-degrading enzyme-like 1, peroxisomal", "gene_name": "PXM16", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAVEKSNTTVGGVEILKPRTDNREYRMIVLKNLLQVLLISDPDTDKCAASMSVSVGSFSDPQGLEGLAHFLEHMLFYASEKYPEEDSYSKYITEHGGSTNAYTASEETNYHFDVNADCFDEALDRFAQFFIKPLMSADATMREIKAVDSENQKNLLSDGWRIRQLQKHLSKEDHPYHKFSTGNMDTLHVRPQAKGVDTRSELIKFYEEHYSANIMHLVVYGKESLDKIQDLVERMFQEIQNTNKVVPRFPGQPCTADHLQILVKAIPIKQGHKLGVSWPVTPSIHHYDEAPSQYLGHLIGHEGEGSLFHALKTLGWATGLSAGEGEWTLDYSFFKVSIDLTDAGHEHMQEILGLLFNYIQLLQQTGVCQWIFDELSAICETKFHYQDKIPPMSYIVDIASNMQIYPTKDWLVGSSLPTKFNPAIVQKVVDELSPSNFRIFWESQKFEGQTDKAEPWYNTAYSLEKITSSTIQEWVQSAPDVHLHLPAPNVFIPTDLSLKDADDKETVPVLLRKTPFSRLWYKPDTMFSKPKAYVKMDFNCPLAVSSPDAAVLTDIFTRLLMDYLNEYAYYAQVAGLYYGVSLSDNGFELTLLGYNHKLRILLETVVGKIANFEVKPDRFAVIKETVTKEYQNYKFRQPYHQAMYYCSLILQDQTWPWTEELDVLSHLEAEDVAKFVPMLLSRTFIECYIAGNVENNEAESMVKHIEDVLFNDPKPICRPLFPSQHLTNRVVKLGEGMKYFYHQDGSNPSDENSALVHYIQVHRDDFSMNIKLQLFGLVAKQATFHQLRTVEQLGYITALAQRNDSGIYGVQFIIQSSVKGPGHIDSRVESLLKNFESKLYEMSNEDFKSNVTALIDMKLEKHKNLKEESRFYWREIQSGTLKFNRKEAEVSALKQLQKQELIDFFDEYIKVGAARKKSLSIRVYGSQHLKEMASDKDEVPSPSVEIEDIVGFRKSQPLHGSFRGCGQPKL", "length": 970 }, "evidence": [ { "id": "A0A8V0ZI42", "url": "https://omabrowser.org/oma/group/A0A8V0ZI42/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P14735-1", "protein_name": "Insulin-degrading enzyme", "gene_name": "IDE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRYRLAWLLHPALPSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQQRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL", "length": 1019 }, "evidence": [ { "id": "A0A8V0ZI42", "url": "https://omabrowser.org/oma/group/A0A8V0ZI42/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P22817-1", "protein_name": "Insulin-degrading enzyme", "gene_name": "Ide", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTIAESSQKSATRKPDSMEPILRLNNIEKSLQDTRDYRGLQLENGLKVLLISDPNTDVSAAALSVQVGHMSDPTNLPGLAHFCEHMLFLGTEKYPHENGYTTYLSQSGGSSNAATYPLMTKYHFHVAPDKLDGALDRFAQFFIAPLFTPSATEREINAVNSEHEKNLPSDLWRIKQVNRHLAKPDHAYSKFGSGNKTTLSEIPKSKNIDVRDELLKFHKQWYSANIMCLAVIGKESLDELEGMVLEKFSEIENKNVKVPGWPRHPYAEERYGQKVKIVPIKDIRSLTISFTTDDLTQFYKSGPDNYLTHLIGHEGKGSILSELRRLGWCNDLMAGHQNTQNGFGFFDIVVDLTQEGLEHVDDIVKIVFQYLEMLRKEGPKKWIFDECVKLNEMRFRFKEKEQPENLVTHAVSSMQIFPLEEVLIAPYLSNEWRPDLIKGLLDELVPSKSRIVIVSQSFEPDCDLAEPYYKTKYGITRVAKDTVQSWENCELNENLKLALPNSFIPTNFDISDVPADAPKHPTIILDTPILRVWHKQDNQFNKPKACMTFDMSNPIAYLDPLNCNLNHMMVMLLKDQLNEYLYDAELASLKLSVMGKSCGIDFTIRGFSDKQVVLLEKLLDHLFDFSIDEKRFDILKEEYVRSLKNFKAEQPYQHSIYYLALLLTENAWANMELLDAMELVTYDRVLNFAKEFFQRLHTECFIFGNVTKQQATDIAGRVNTRLEATNASKLPILARQMLKKREYKLLAGDSYLFEKENEFHKSSCAQLYLQCGAQTDHTNIMVNLVSQVLSEPCYDCLRTKEQLGYIVFSGVRKVNGANGIRIIVQSAKHPSYVEDRIENFLQTYLQVIEDMPLDEFERHKEALAVKKLEKPKTIFQQFSQFYGEIAMQTYHFEREEAEVAILRKISKADFVDYFKKFIAKDGEERRVLSVHIVSQQTDENATSEAEPVEITNMERHKPISDIVTFKSCKELYPIALPFLDIKAKGARSKL", "length": 990 }, "evidence": [ { "id": "A0A8V0ZI42", "url": "https://omabrowser.org/oma/group/A0A8V0ZI42/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P35559-1", "protein_name": "Insulin-degrading enzyme", "gene_name": "Ide", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNGLVWLLHPALPSTLHSILGARPPPVKRLCGFPKQIYSTMNNPAIQRIEDHIVKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIPGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDASCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVREELLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQQYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGKLHYYPLNGVLTAEYLLEEFRPDLIDMVLDKLRPENVRVAIVSKSFEGKTDRTEQWYGTQYKQEAIPEDVIQKWQNADLNGKFKLPTKNEFIPTNFEILALEKDATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKITEKMATFEIDKKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGVMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQRRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKAIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNYDRDNIEVAYLKTLSKDDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGEFPSQNDINLSEAPPLPQPEVIHNMTEFKRGLPLFPLVKPHINFMAAKL", "length": 1019 }, "evidence": [ { "id": "A0A8V0ZI42", "url": "https://omabrowser.org/oma/group/A0A8V0ZI42/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q06010-1", "protein_name": "A-factor-processing enzyme", "gene_name": "STE23", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGVSLLASSSAFVTKPLLTQLVHLSPISLNFTVRRFKPFTCLSRYYTTNPYNMTSNFKTFNLDFLKPDLDERSYRFIELPNKLKALLIQDPKADKAAASLDVNIGAFEDPKNLPGLAHFCEHLLFMGSEKFPDENEYSSYLSKHGGSSNAYTASQNTNYFFEVNHQHLFGALDRFSGFFSCPLFNKDSTDKEINAVNSENKKNLQNDIWRIYQLDKSLTNTKHPYHKFSTGNIETLGTLPKENGLNVRDELLKFHKNFYSANLMKLCILGREDLDTLSDWTYDLFKDVANNGREVPLYAEPIMQPEHLQKIIQVRPVKDLKKLEISFTVPDMEEHWESKPPRILSHLIGHEGSGSLLAHLKKLGWANELSAGGHTVSKGNAFFAVDIDLTDNGLTHYRDVIVLIFQYIEMLKNSLPQKWIFNELQDISNATFKFKQAGSPSSTVSSLAKCLEKDYIPVSRILAMGLLTKYEPDLLTQYTDALVPENSRVTLISRSLETDSAEKWYGTAYKVVDYPADLIKNMKSPGLNPALTLPRPNEFVSTNFKVDKIDGIKPLDEPVLLLSDDVSKLWYKKDDRFWQPRGYIYLSFKLPHTHASIINSMLSTLYTQLANDALKDVQYDAACADLRISFNKTNQGLAITASGFNEKLIILLTRFLQGVNSFEPKKDRFEILKDKTIRHLKNLLYEVPYSQMSNYYNAIINERSWSTAEKLQVFEKLTFEQLINFIPTIYEGVYFETLIHGNIKHEEALEVDSLIKSLIPNNIHNLQVSNNRLRSYLLPKGKTFRYETALKDSQNVNSCIQHVTQLDVYSEDLSALSGLFAQLIHEPCFDTLRTKEQLGYVVFSSSLNNHGTANIRILIQSEHTTPYLEWRINNFYETFGQVLRDMPEEDFEKHKEALCNSLLQKFKNMAEESARYTAAIYLGDYNFTHRQKKAKLVANITKQQMIDFYENYIMSENASKLILHLKSQVENKELNENELDTAKYPTGQLIEDVGAFKSTLFVAPVRQPMKDFEISAPPKLNNSSESE", "length": 1027 }, "evidence": [ { "id": "A0A8V0ZI42", "url": "https://omabrowser.org/oma/group/A0A8V0ZI42/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q24K02-1", "protein_name": "Insulin-degrading enzyme", "gene_name": "IDE", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"length": 1019 }, "evidence": [ { "id": "A0A8V0ZI42", "url": "https://omabrowser.org/oma/group/A0A8V0ZI42/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "ubiquitin recycling", "id": "GO:0010992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010992", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "amyloid-beta metabolic process", "id": "GO:0050435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "hormone catabolic process", "id": "GO:0042447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042447", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "peptide catabolic process", "id": "GO:0043171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "antigen processing and presentation of endogenous peptide antigen via MHC class I", "id": "GO:0019885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019885", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "regulation of aerobic respiration", "id": "GO:1903715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903715", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "proteolysis involved in protein catabolic process", "id": "GO:0051603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051603", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "bradykinin catabolic process", "id": "GO:0010815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "insulin catabolic process", "id": "GO:1901143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901143", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "amyloid-beta clearance by cellular catabolic process", "id": "GO:0150094", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150094", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "protein catabolic process", "id": "GO:0030163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030163", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "amyloid-beta clearance", "id": "GO:0097242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "peptide binding", "id": "GO:0042277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "insulin binding", "id": "GO:0043559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043559", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 996, "end_pos": 998, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-5696872", "name": "USP30 deubiquitinates Ub-MOM proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, mitochondrial outer membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1ADZ7-1", "E1BWS4-1", "A0A8V0ZJW5-1", "A0A8V1A2D9-1", "A0A8V0ZG42-1", "A0A8V0ZI42-1" ], "evidence": [ { "id": "R-GGA-5696872", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696872" } ] }, { "id": "R-GGA-74730", "name": "Insulin degradation", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "endosome", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q05744-1", "A0A8V0ZI42-1" ], "evidence": [ { "id": "R-GGA-74730", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-74730" } ] }, { "id": "R-GGA-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033235" } ] }, { "id": "R-GGA-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033236" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P3W4", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] } ] }, { "uniprot_ac": "A0A1D5PZB7", "gene_name": "NOS2", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] } ] }, { "uniprot_ac": "A0A1L1RJ90", "gene_name": "HMGCL", "activity": [ { "ec_number": "4.1.3.4", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] }, { "ec_number": "4.1.3.4", "activity": "", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] } ] }, { "uniprot_ac": "A0A8V0XEK2", "gene_name": "HACL1", "activity": [ { "ec_number": "4.1.2.63", "activity": "2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] }, { "ec_number": "4.1.2.63", "activity": "", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] } ] }, { "uniprot_ac": "A0A8V0XIT0", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] } ] }, { "uniprot_ac": "A0A8V0XXY0", "gene_name": "MLYCD", "activity": [ { "ec_number": "4.1.1.9", "activity": "malonyl-CoA + H(+) = acetyl-CoA + CO2.", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] }, { "ec_number": "4.1.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] } ] }, { "uniprot_ac": "A0A8V0Y1Q3", "gene_name": "NUDT7", "activity": [ { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] } ] }, { "uniprot_ac": "A0A8V0Y2T0", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] } ] }, { "uniprot_ac": "A0A8V0YAP6", "gene_name": "GNPAT", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] } ] }, { "uniprot_ac": "A0A8V0YMJ0", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZC97", "gene_name": "PEX10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] } ] }, { "uniprot_ac": "A0A8V0ZG42", "gene_name": "MUL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZG42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG42" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZG42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG42" } ] } ] }, { "uniprot_ac": "A0A8V0ZI42", "gene_name": "IDE", "activity": [ { "ec_number": "3.4.24.56", "activity": "Degradation of insulin, glucagon and other polypeptides. No action on proteins.", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] }, { "ec_number": "3.4.24.56", "activity": "", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] } ] }, { "uniprot_ac": "A0A8V0ZIT7", "gene_name": "PECR", "activity": [ { "ec_number": "1.3.1.38", "activity": "a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+).", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] }, { "ec_number": "1.3.1.38", "activity": "", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] } ] }, { "uniprot_ac": "A0A8V0ZJW5", "gene_name": "USP30", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A0A8V0ZJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW5" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A0A8V0ZJW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW5" } ] } ] }, { "uniprot_ac": "A0A8V0ZLD0", "gene_name": "TYSND1", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0A8V0ZLD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD0" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQU7", "gene_name": "PAOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZRI7", "gene_name": "LONP2", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI7" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V1A097", "gene_name": "HAO2", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] } ] }, { "uniprot_ac": "A0A8V1A124", "gene_name": "AGXT", "activity": [ { "ec_number": "2.6.1.51", "activity": "L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.51", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] } ] }, { "uniprot_ac": "A0A8V1A248", "gene_name": "EHHADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "4.2.1.17", "activity": "(3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O.", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "4.2.1.17", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] } ] }, { "uniprot_ac": "A0A8V1A2D9", "gene_name": "FKBP8", "activity": [ { "ec_number": "5.2.1.8", "activity": "[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0).", "evidence": [ { "id": "A0A8V1A2D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2D9" } ] }, { "ec_number": "5.2.1.8", "activity": "", "evidence": [ { "id": "A0A8V1A2D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2D9" } ] } ] }, { "uniprot_ac": "A0A8V1A8Z1", "gene_name": "SCP2", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] } ] }, { "uniprot_ac": "A0A8V1ADZ7", "gene_name": "RHOT1", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V1ADZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADZ7" } ] } ] }, { "uniprot_ac": "A0A8V1AJL7", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.7", "activity": "", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] } ] }, { "uniprot_ac": "A0A8V1ANC5", "gene_name": "PIPOX", "activity": [ { "ec_number": "1.5.3.1", "activity": "sarcosine + O2 + H2O = formaldehyde + glycine + H2O2.", "evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] }, { "ec_number": "1.5.3.7", "activity": "L-pipecolate + O2 = L-1-piperideine-6-carboxylate + H2O2 + H(+).", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIL1-1", "uniprot_ac": "A0A8V0ZIL1", "uniprot_id": "A0A8V0ZIL1_CHICK", "mass": { "chemical_mass": 213704.0, "monoisotopic_mass": 213704.0 }, "refseq": { "ac": "NP_001272798", "name": "treslin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272798" }, "gene_names": [ { "name": "TICRR", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" } ] }, { "name": "C10H15ORF42", "type": "synonym", "evidence": [ { "id": "NP_001272798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272798" } ] }, { "name": "C15orf42", "type": "synonym", "evidence": [ { "id": "NP_001272798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272798" } ] }, { "name": "SLD3", "type": "synonym", "evidence": [ { "id": "NP_001272798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272798" } ] }, { "name": "TICRR", "type": "synonym", "evidence": [ { "id": "NP_001272798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272798" } ] }, { "name": "treslin", "type": "synonym", "evidence": [ { "id": "NP_001272798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272798" } ] } ], "protein_names": [ { "name": "SLD3 homolog", "type": "synonym", "evidence": [ { "id": "NP_001272798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272798" } ] }, { "name": "TOPBP1 interacting checkpoint and replication regulator", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1/entry#names_and_taxonomy" } ] }, { "name": "topBP1-interacting, replication-stimulating protein", "type": "synonym", "evidence": [ { "id": "NP_001272798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272798" } ] }, { "name": "treslin", "type": "synonym", "evidence": [ { "id": "NP_001272798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272798" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN06143078 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On Sep 23, 2021 this sequence version replaced NP_001272798.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001272798", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272798" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TICRR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1", "locus": { "chromosome": "10", "start_pos": 12850904, "end_pos": 12867466, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019948", "url": "https://www.ensembl.org/id/ENSGALG00010019948" } ] } } ], "crossref": [ { "id": "415489", "url": "https://www.ncbi.nlm.nih.gov/gene/415489", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032746", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032746", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415489", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415489", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LYWMEKL", "url": "https://omabrowser.org/oma/group/LYWMEKL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCK4", "url": "https://www.orthodb.org/?gene=A0A8V0ZCK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIL1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21556", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21556", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21556:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21556:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-69273", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001272798", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001272798", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACSPSAVFLLDTASPGRRERLQLCALRLLNHLCCRFGLPRLRWAYRFFDSLGGRGGASRGGGFRPPAPRAWARFEEELAERLGARGSSAVLPGPATRLALTHSGLKETLLDFQWDRPEIASPTKAPRRSRGAGGELPASGAPSEGFVNAVFLFSPCPRSRRELRQFVSGGGAAPAEPPALQEVAEKLLPRSVRELLAEQRITLYWVDTAESSQLIKSPDHDGYWIMLQLLQQIGGTILPSETLYPSHHKADLADVFLRDSGSPVPQTVPWTTLLPSDSALNSLFSKPSVFYSVFPQQEGTLFLSMPEGKKESCAVILEPLAMSQRQLHCPFNIILKGSVMSWNWMQAVSFLTESWILKSSETECTEQNWLHQLLRSLVMKELHMIAEVSQTTSSCPCTAVLSPLSESSAVLTLFCTEKTAEVQRCNLEGAVVETSSPDDALHLPDVVHSVLSEIDMAVEDSLANTEETPVPEWVQRELSSTGGWHPSVLEAWYSSSNACGASSDLMDSFRLLQVPCTNVKDDADQSEVELLESLSELYQRKSSEISAGAGNNKKRRGVPRTPVRQKMKTMSRSLQMLNVARLNVKAQKFQPDGMPAVSEKVPQKLSAKRLDEKLEGKEKALKTSIDLKTEEELQSHLITSYQKVVAEEVLSSACAQNMIMAIKRFLKMQDTKEKEVACVEKVRNHLLKTSKLLRQQHGSEKETKVRECRLQVFLRLELCLQCPSLQNNADEMEQLLEEMTDMLRILCLTEDPGYLTKFLEEILELYMNSIPKTLGDLYYSLGTQIPPKLASVLPSDFFSDDSMTVDSKSPGLPLSLSSVLTPTAVCLQSESDQLEELRTRSAQKRRNNVLARHRSMTEASQNLRQIEIPKIDKNPIRKESSRSYLATEKSQQMPLQKEAVQEVTKVRRNLFNEGIRSPSKRTTKKMPRSQSVSAVEGLRYKCTDEGAKGHHKLLTKRVAETPLHKQVSRRLLHKQIKGRSSDPGCETGVVEESPEKAISEAGLRRSPRIRQLTLNRTHSGVFCSTVQPSSQNSQQVHWGQEEESCTQQDVAGVGLHSGCPTPKRFFFGAVIDACSPTVKRSPGRRRTRKDSLNLEELTACQTPRKTPLKSAQKLLNSASKPLRRSPRILHRTPQKVEKTPSKSPAAKQTAAKCLGKYFSHPAPRIRSPSVLTEGKRACLMQVTKDCSPAEKLFSPYKETDLQLPEHNEILSTVNPSPPQDSAPAAASLPATQKSIFAELQTPRRSLRSLSKFASPVGARRQILPREIEMQPEPASQTTETTPRKAEDPGSKLPTSPLSDVEMSQLTVKLESPFSSPLSEKATNTAAVSSPSHTEAKESDREFNVPENSLLKSPGVGGTLLESPLNNSKQAKGNPDSGGENHTCVCETPSKSKGGHRDNGDNSCVESLQFCKSQIPENNHILENKQMDAVAQNSPPRKDSKNLEKHSSPKLSAGEHMLNAEMECEQSSKEGNSSVSTCESFLSSSQTSIDELEPKTPQREECTGPKAPSLKRRSRSARNTSPPLPKSAPAYSLRYTADRRQREAAARMGNPELPAKFSAPKIPCQQPSESSTAYEVELEMQASGLPKLRFKKIGSCSALDVQSETNVSKPKGGESPFGDLAMTWCSKHPGKLAAACVSPSCFRSFHGTPGKGGGQTYICQSYTPTSCASNTTSPSPLEAEVPLTPPKLKGKTTPDAIKDWPRRKRAVSSTANSSCVQSEKNADEAMSTSREGKLKDLENCSSKVTCAFGEFELEGIYRLQDQVSPNDTEPRDEERSAMGASGLTSRKRVFTYLSPEKEENHEAKRACTDKCNMVLNAFSPEEGNRNKARTDLVLPEKPRACLLLTPRQHICIGDDDVFPLSGATPPVKSSLSASSLLALTQSPLLCKGQTPPSRRKCVQDEESDDPEVITNQELSPFHSMASRRRSLSRTYSRKRLLS", "length": 1938, "header": "tr|A0A8V0ZIL1-1|A0A8V0ZIL1_CHICK Isoform 1 of TOPBP1 interacting checkpoint and replication regulator OS=Gallus gallus OX=9031 GN=TICRR PE=4 SV=1 CANONICAL=A0A8V0ZIL1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1/entry#A0A8V0ZCK4-1", "sequence": { "sequence": "MACSPSAVFLLDTASPGRRERLQLCALRLLNHLCCRFGLPRLRWAYRFFDSLGGRGGASRGGGFRPPAPRAWARFEEELAERLGARGSSAVLPGPATRLALTHSGLKETLLDFQWDRPEIASPTKAPRRSRGAGGELPASGAPSEGFVNAVFLFSPCPRSRRELRQFVSGGGAAPAEPPALQEVAEKLLPRSVRELLAEQRITLYWVDTAESSQLIKSPDHDGYWIMLQLLQQIGGTILPSETLYPSHHKADLADVFLRDSGSPVPQTVPWTTLLPSDSALNSLFSKPSVFYSVFPQQEGTLFLSMPEGKKESCAVILEPLAMSQRQLHCPFNIILKGSVMSWNWMQAVSFLTESWILKSSETECTEQNWLHQLLRSLVMKELHMIAEVSQTTSSCPCTAVLSPLSESSAVLTLFCTEKTAEVQRCNLEGAVVETSSPDDALHLPDVVHSVLSEIDMAVEDSLANTEETPVPEWVQRELSSTGGWHPSVLEAWYSSSNACGASSDLMDSFRLLQVPCTNVKDDADQSEVELLESLSELYQRKSSEISAGAGNNKKRRGVPRTPVRQKMKTMSRSLQMLNVARLNVKAQKFQPDGMPAVSEKVPQKLSAKRLDEKLEGKEKALKTSIDLKTEEELQSHLITSYQKVVAEEVLSSACAQNMIMAIKRFLKMQDTKEKEVACVEKVRNHLLKTSKLLRQQHGSEKETKVRECRLQVFLRLELCLQCPSLQNNADEMEQLLEEMTDMLRILCLTEDPGYLTKFLEEILELYMNSIPKTLGDLYYSLGTQIPPKLASVLPSDFFSDDSMTVDSKSPGLPLSLSSVLTPTAVCLQSESDQLEELRTRSAQKRRNNVLARHRSMTEASQNLRQIEIPKIDKNPIRKESSRSYLATEKSQQMPLQKEAVQEVTKVRRNLFNEGIRSPSKRTTKKMPRSQSVSAVEGLRYKCTDEGAKGHHKLLTKRVAETPLHKQVSRRLLHKQIKGRSSDPGCETGVVEESPEKAISEAGLRRSPRIRQLTLNRTHSGVFCSTVQPSSQNSQQVHWGQEEESCTQQDVAGVGLHSGCPTPKRFFFGAVIDACSPTVKRSPGRRRTRKDSLNLEELTACQTPRKTPLKSAQKLLNSASKPLRRSPRILHRTPQKVEKTPSKSPAAKQTAAKCLGKYFSHPAPRIRSPSVLTEGKRACLMQVTKDCSPAEKLFSPYKETDLQLPEHNEILSTVNPSPPQDSAPAAASLPATQKSIFAELQTPRRSLRSLSKFASPVGARRQILPREIEMQPEPASQTTETTPRKAEDPGSKLPTSPLSDVEMSQLTVKLESPFSSPLSEKATNTAAVSSPSHTEAKESDREFNVPENSLLKSPGVGGTLLESPLNNSKQAKGNPDSGGENHTCVCETPSKSKGGHRDNGDNSCVESLQFCKSQIPENNHILENKQMDAVAQNSPPRKDSKNLEKHSSPKLSAGEHMLNAEMECEQSSKEGNSSVSTCESFLSSSQTSIDELEPKTPQREECTGPKAPSLKRRSRSARNTSPPLPKSAPAYSLRYTADRRQREAAARMGNPELPAKFSAPKIPCQQPSESSTAYEVELEMQASGLPKLRFKKIGSCSALDVQSETNVSKPKGGESPFGDLAMTWCSKHPGKLAAACVSPSCFRSFHGTPGKGGGQTYICQSYTPTSCASNTTSPSPLEAEVPLTPPKLKGKTTPDAIKDWPRRKRAVSSTANSSCVQSEKNADEAMSTSREGKLKDLENCSSKVTCAFGEFELEGIYRLQDQVSPNDTEPRDEERSAMGASGLTSRKRVFTYLSPEKEENHEAKRACTDKCNMVLNAFSPEEGNRNKARTDLVLPEKPRACLLLTPRQHICIGDDDVFPLSGN", "length": 1863, "header": "tr|A0A8V0ZCK4-1|A0A8V0ZIL1_CHICK Computationally mapped isoform of TOPBP1 interacting checkpoint and replication regulator OS=Gallus gallus OX=9031 GN=TICRR PE=4 SV=1 CANONICAL=A0A8V0ZIL1-1" }, "locus": { "chromosome": "10", "start_pos": 12867378, "end_pos": 12853157, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048165.1", "url": "https://www.ensembl.org/id/ENSGALT00010048165.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028413.1", "url": "https://www.ensembl.org/id/ENSGALP00010028413.1" } ] } }, { "isoform_ac": "A0A8V0ZIL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1/entry#A0A8V0ZIL1-1", "sequence": { "sequence": "MACSPSAVFLLDTASPGRRERLQLCALRLLNHLCCRFGLPRLRWAYRFFDSLGGRGGASRGGGFRPPAPRAWARFEEELAERLGARGSSAVLPGPATRLALTHSGLKETLLDFQWDRPEIASPTKAPRRSRGAGGELPASGAPSEGFVNAVFLFSPCPRSRRELRQFVSGGGAAPAEPPALQEVAEKLLPRSVRELLAEQRITLYWVDTAESSQLIKSPDHDGYWIMLQLLQQIGGTILPSETLYPSHHKADLADVFLRDSGSPVPQTVPWTTLLPSDSALNSLFSKPSVFYSVFPQQEGTLFLSMPEGKKESCAVILEPLAMSQRQLHCPFNIILKGSVMSWNWMQAVSFLTESWILKSSETECTEQNWLHQLLRSLVMKELHMIAEVSQTTSSCPCTAVLSPLSESSAVLTLFCTEKTAEVQRCNLEGAVVETSSPDDALHLPDVVHSVLSEIDMAVEDSLANTEETPVPEWVQRELSSTGGWHPSVLEAWYSSSNACGASSDLMDSFRLLQVPCTNVKDDADQSEVELLESLSELYQRKSSEISAGAGNNKKRRGVPRTPVRQKMKTMSRSLQMLNVARLNVKAQKFQPDGMPAVSEKVPQKLSAKRLDEKLEGKEKALKTSIDLKTEEELQSHLITSYQKVVAEEVLSSACAQNMIMAIKRFLKMQDTKEKEVACVEKVRNHLLKTSKLLRQQHGSEKETKVRECRLQVFLRLELCLQCPSLQNNADEMEQLLEEMTDMLRILCLTEDPGYLTKFLEEILELYMNSIPKTLGDLYYSLGTQIPPKLASVLPSDFFSDDSMTVDSKSPGLPLSLSSVLTPTAVCLQSESDQLEELRTRSAQKRRNNVLARHRSMTEASQNLRQIEIPKIDKNPIRKESSRSYLATEKSQQMPLQKEAVQEVTKVRRNLFNEGIRSPSKRTTKKMPRSQSVSAVEGLRYKCTDEGAKGHHKLLTKRVAETPLHKQVSRRLLHKQIKGRSSDPGCETGVVEESPEKAISEAGLRRSPRIRQLTLNRTHSGVFCSTVQPSSQNSQQVHWGQEEESCTQQDVAGVGLHSGCPTPKRFFFGAVIDACSPTVKRSPGRRRTRKDSLNLEELTACQTPRKTPLKSAQKLLNSASKPLRRSPRILHRTPQKVEKTPSKSPAAKQTAAKCLGKYFSHPAPRIRSPSVLTEGKRACLMQVTKDCSPAEKLFSPYKETDLQLPEHNEILSTVNPSPPQDSAPAAASLPATQKSIFAELQTPRRSLRSLSKFASPVGARRQILPREIEMQPEPASQTTETTPRKAEDPGSKLPTSPLSDVEMSQLTVKLESPFSSPLSEKATNTAAVSSPSHTEAKESDREFNVPENSLLKSPGVGGTLLESPLNNSKQAKGNPDSGGENHTCVCETPSKSKGGHRDNGDNSCVESLQFCKSQIPENNHILENKQMDAVAQNSPPRKDSKNLEKHSSPKLSAGEHMLNAEMECEQSSKEGNSSVSTCESFLSSSQTSIDELEPKTPQREECTGPKAPSLKRRSRSARNTSPPLPKSAPAYSLRYTADRRQREAAARMGNPELPAKFSAPKIPCQQPSESSTAYEVELEMQASGLPKLRFKKIGSCSALDVQSETNVSKPKGGESPFGDLAMTWCSKHPGKLAAACVSPSCFRSFHGTPGKGGGQTYICQSYTPTSCASNTTSPSPLEAEVPLTPPKLKGKTTPDAIKDWPRRKRAVSSTANSSCVQSEKNADEAMSTSREGKLKDLENCSSKVTCAFGEFELEGIYRLQDQVSPNDTEPRDEERSAMGASGLTSRKRVFTYLSPEKEENHEAKRACTDKCNMVLNAFSPEEGNRNKARTDLVLPEKPRACLLLTPRQHICIGDDDVFPLSGATPPVKSSLSASSLLALTQSPLLCKGQTPPSRRKCVQDEESDDPEVITNQELSPFHSMASRRRSLSRTYSRKRLLS", "length": 1938, "header": "tr|A0A8V0ZIL1-1|A0A8V0ZIL1_CHICK Isoform 1 of TOPBP1 interacting checkpoint and replication regulator OS=Gallus gallus OX=9031 GN=TICRR PE=4 SV=1 CANONICAL=A0A8V0ZIL1-1" }, "locus": { "chromosome": "10", "start_pos": 12867378, "end_pos": 12851217, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048182.1", "url": "https://www.ensembl.org/id/ENSGALT00010048182.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028416.1", "url": "https://www.ensembl.org/id/ENSGALP00010028416.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415489", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415489", "resource": "KEGG Pathway" }, { "id": "R-GGA-69273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69273", "resource": "Reactome", "description": "Cyclin A/B1/B2 associated events during G2/M transition" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L4N7-1", "protein_name": "TOPBP1-interacting checkpoint and replication regulator", "gene_name": "Ticrr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACCHKVMLLVDTAGDAARHSSARRAALRLLTYLSCRFGLARVHWTFKFFDSQGARNRPSRVSDFRELGSRSWEDFEEELEARLGDRPPGAHLPGPTPRATHTHGALMETLLDYQWDRPEITSPTKPILRSSGRRLLDADSEAKEAETALGGFGNAVFLLAPCPHSQRELLQFVSGCEAQAQRVPLTPKQLMEKVLPKRVQEVMIARNITLYWVDTTERSKLWASPDHTGYWTVCELLHHGGGTILPAETWNLGFTKARETVLPCGGELSPGPHLSPWISALPIDATVNCLLYNSEYEASFPRVEGTLFLPVKGKEIQETWAICLEPLAMHQRHFQKPVRIFLKGSVTQWSLPMSSALGTDNWMLQSPEEHKSTQRLLFQELVSRLTAEEFHLVASVDPGDGWPPITGIISPFSANAMILTVLRAKEAEFQRHFLQTAVTEGSQDVTSLFSDAVDSVLNQVHNSFEDPASSVSRVPEWVQQELSRTSPWSPALVEKWFPFSNVCGATSDLMESFLLLHAASPDNNESSRTESELTRCLSELYQRRSHEESTVVNQERSRKKRGIPRTPVRQKMNTMSRSLKMLNVARLNVKAQKLHPDGSPDMAVEKGLPKTVIGRTADKLEDRGRVLRSSKLKEFKTEEELLAYIHDNYQKTVATGEITLHSCAQNTVSTIKIFLKSKDVKELEMTCMNHMNSNLLKTSKTLRQNLGGKTDKEDKVRECQLQVFLRLEMCQQCPSVLDRTEEVEHVVEEVTDLLRVVCLTKDSAYLSEFLEEILGLYIDSIPGTIGQLYHSLGLKIPQKLAGVLPTDFFSDDSMTQESMSPPPSSSTHRSVSAITESEQLEELRTRSAKKRRKNALIRHKSIAEISQALRQIEVPKVSKRATRSASNPRTWSTEESAHPASVQLPLPRKDTVQEVTKVRRNLFNQGMLSPSKRGLKKGLPRSRSVSTLECLQHKQDKLKKTKSSTFQGYKLLTKSVAETPVHKQISRRLLHRQIKGRSSDPGPDIHVVEESPEKEDEMILRRSPRIKQLSFSRTNSGSFYSVSQPKSRSVQRIHSSQQKSDQRENFPVQSIRSPKTLLFGALSETPSSSKKGSPGIKRSSRSMLDSEISTAYETPKKNNQKSPSFSKTTPRSFPRTAQTLLYTPERLQNSSTEITSAEGTISEVAIKTPSSHGYNSPSASKVTPQKRASPAKEETSPLTELPSIPRESDVQPPQCSSNSVSSSSEGPCCPASPPPLAGQARGQCLTPVRYSFRTPPRTALAVTSTYQEHQELPLRRASQAREPPQRLEEKALKIPKKPTDTSTSPLSPKEHFTSPGCNVSPHQPSISSLSASPSGELSWKENQTSPSVTTSVSCPVPSTPPRTPQRMICPIPPSPPSKLRRPCRKKSCLPQDFPECQPGPCAVPVLGTTTSPGTVRGSREEQSQPSEGHSYLGTSFGSDWHVSSPMLIASDTECLPLIDEAQLHRLENQEVKSGVLPGEEGEEPETTTAEPPSVSDLGILVPAPSSVSNSPELLSYTLCRVADGRQSHDAAQQESPPASEATDSPQTYDVELEMQASGLPKLRIKKIDPGVLLEPEALGRETLLGEEGTFPALSMPKASKSSGRSEHTYLSPPCLLPSHSTPGKSGGQTFICQSCTPSRCPPSTPSPFQADVGVSWTPSPKQSGKTTPEIIKDWPRRKRAVDCSAGPSAGRGEASMDLPGSLSLLEPEPEGKEQSLEQDLCKVLILEDFELEGVCQLPDQSPPKHSVSMAEETSWEQFGLGRKRLLSAKEESEYNGKRLCDSPSEDPQASEHKECSPCWSAPPVPSVGDDEVFVSGSTPPSGYMVRSCLSASGLQALTQSPLLFQGRTPSSHSKDTRDEDVDVFPSTAEESPFSQTLSRKRPFRTYTRKKLIS", "length": 1894 }, "evidence": [ { "id": "A0A8V0ZIL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZIL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BPF2-1", "protein_name": "TOPBP1 interacting checkpoint and replication regulator", "gene_name": "TICRR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MACCHNVMLLLDTAGGVAGESLVRRAALRLLTYLSCRFGLARVRWAFRFFDSQGARSRPSRVSDFRELGVRSWEDFEEELEARLGDGAQGAHLPGPAPRASHTHSALMETLLDYQWDRPEITSPTKPILRNSGRRLLDVEGEAREAESALGGFVNAVFLLAPCPHSQRELLQFVSGSEAQAQRLPPTPKQVMEKLLPRKVQEVMRTRKITLYWVDTTEWPKLWESPDHLGYWTVCELLYHVGGTVLPFESFSQDFTKAGETLLSGERKLSSKPHLSSWISTLPTDSTLNCLLYNSPEYEASFPRIEGTLFFPVEGKELQETWTVTLEPLAMHQRHFQKPVRIFLKGTVTQWSLPTSGTLGTDSWMLQSPDGDRSTQRMLFQHLVNRLTAEELHLVASVDPGEGWPPITGVISPFSVGATVLTLFCTRETESQRHLLQTVVAESPQDSAALFSEVVDGVLKQIDSSLEVPATSDLPVPEWAQQELGRSAPWTSAIVEKWFPCSNLSGASSSLMESFWLLQATSSAKEEPSKTESDLTRGLSELYQRKSREEYSVSSQEDSRKKRGVPRTPVRKKMNTMCRSLKMLNVARLNVKAQKLHPDGSPDTAGEKGIQKTANGRTADRLENRGRTLRSSKPKDFKTEEELLSHIHENYQKTVAAGDTMLYSCARSTISNIKAFLKSKGTKELEEASLEMNCLYQVRNNFLKTSKSLRQNVGKLDKEGKVRECQLQVFLRLELCLQCPSVHERVEDLEQVVGEVTDLLRMLCLTEDSAYLAKFLEGILELYIDSIPKILGSLYDSLGFVIPQKLAGVLPADFFSDDSMTQESKSPLSVPLPSNAHRSLPGGTESDQLEELRTRSAKKRRKNAIRHKSIAEVSQNLRQIEIPKVAKRATKNENSHPTLQQQPPLPVKDTVQEVTKVRRNLFNQEMISPSKRSVKKGLPRSHSVSAVEGLEYKRDSFKRTKGYRKLLTKSVAETPVHKQISGRLLHRQIKGRSSDPGPDIDVVEESPEKGEDVVSLRRSPRIKQLAFSRTNSASFYSVSQPKSRSIQRVHSFQQMKSDQRENSPVQSIRSPKRLLFGAMSEMISPSEKGSARIKRPSGNTVGSATPTAYQTPEKSYWKSPSSCKATPRKVPRTPQTPLRTPERLQKSPAEMTPAKQVIFKEFLKDLSPHGWDSPSQPKVTPRKGHSLAEGASSLEKVRRTPQRQSGQPPRFLQNSSWPHLVDSSPESTSCPAALVSSTAPTRTECLTPNRSSARAPPRTAASGLQRQAASKGTSPSQKHQLPQGSGAPRAEKLPQLWSNKAVKTPERPGNAALTFPKRAVTSLSCGISKESSLGEFPIASLSSGQGGWQEVQRSPSVTTPPSCSAPLTPPSASQVAPSDLWPPPPPSKHGKRHNKTSETEQDFLEGQPDSLAALRVAITDNPAAITDTGKNQKAATLSSPASPELPAYPGTGFGGDWHTSSPLLIATDSDCLTLLDEAEHHGHDNLKSSISPLDGGEGLRMGTCEKPSPCDPRILPTSPSSGPHSPLMPLYDPHCTADMKQCQAATQLEDQQAAPWPCGAPASPQTYEVELEMQASGLPKLRIKKIDSSSLPEVEPPPREESSLPGPSVPRASKSSGKPEATCLSAPCLRPSHSTPGKSGGQTYICQSCTPTHCPCGTPSPFQTEVGVPWTPSPKHSGKTTPDTIKDWPRRKRAVDCSLGPSAGRSEVSSDLPGGVLPLEPEGKERGLELGIGRPPILGDFELEGVCQLPDQSPPRDSVPKAEEAFSWGQFGLGSRKRCLSAEEAAERQVKRACDQQGDSEERSPSTSIRQLPSAADDEVFVPGATPPPGCAVRSCLSASGLQALTHSPLLFQGKTPSSQRKEARDEDVDVFSPTAEDSPFSRAFSRRRPIGRSYSRKKLLS", "length": 1902 }, "evidence": [ { "id": "A0A8V0ZIL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZIL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SK20-1", "protein_name": "TOPBP1 interacting checkpoint and replication regulator", "gene_name": "TICRR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MACCHNVMLLLDTAGGAAGESPVRRAALRLLTYLSCRFGLARVRWAFRFFDSQGARSRPSRVSDFRELGVRSWEDFEEELEARLGDGARGAHLPGPAPRATHTHSALMETLLDYQWDRPEITSPTKPILRSSRRRLLDVEGEAKEAASALGSFVNAVFLLGPCPHSQRELLQFVAGCEAQAQRLPPSPKQVMDKLLPRRVQEVMIARKITLYWVDTTEWSKLWESPDHVGYWTVCELLRHVGGTVLPFETFSQDFTKTGGMPLGSESKLFREPRLSSWISTLPTDSTLNCLLYNSHEYEASFPRMEGTLFLPVEGKETQETWTVMLEPLAMYQRHFQKPVRIFLKGTVTKWSLPTSGPLSTDSWMLQSLEGNRSTQRMLFQQLVNRLAAEELHLVASVDPGEGWPPITGVISPFSASATVLTVFHAKETEFQRHFVQTVLAERPQDSASLLSEVMDGVLNQIHHSLEDPATSAPPVPEWAQQELGRTTPWSSTIVEKWFPCSNLSGASSNLMESFWLLQAASSNKEESSKTESELTRCLSEFYQGKSREESTGYNQEDSRKKRGVPRTPVRQKMNTMCRSLKMLNVARLNVKAQKLHPDGSPDTAGEKGIQKIASGRTTDKLENRGRTLRSSKPKGFKTEEELLSYIHENYQKTMATGEITLYSCARNMISNIKAFLKSRGPKELDMNCLHQVRNNLLKTSKSLRQNVGKLDKEDKVRECQLQVFLRLELCLQCPSIHESIDDMEQVVEEMTDLLRMMYLTEDSAYLAKFLEEILGLYSDSIPETLGKLYNSLGFVIPQKLAGVLPTDFFSDDSMTQESKSPLSVPLMSSAHRSVSGGTESDQLEELRTRSAKKRRKNAIRHKSIAEVSQNLRQIEIPKVSKRATKNENSQPSLQQPPLPVKETVQEVTKVRRNLFNQEMISPSKRSVKRGLPRSHSVSAVEDLDNFKRTKGFHKLLTKSVAETPVHKQISRRLLHRQIKGRSSDPGPDIDVVEESPEKGEDEVSLRRSPRIKQLSFGRTNSGSFYSVSQPKSRSIQRVHSFQQVKSDQRENSPIQSIRSPKRLLFGAVSEMISPSEKGSARIKRPSGNTMDSAMLTAYQTPEKRSWKCPSSKATPRRYPHTPQTPLRTPERLQGSPAEMTPAKQVIFKEFLKEDSSHSWDSPCQSKVTPRKGLSLVEGASPLKTILRTPQRPGSQPSRFLQNSSWPSLVNSSPESTSCSAAVVPSTAQTRGECLTPIRYSPRTPSRAAALRVQGEAAFMGTPPTQKHQLPWGSAASQAEKLARQRKNEAVKTPGRPGDTALTSPKKPLTSSLCAVSKSPFRKLPVDSPPPGEQDWREVQKSASTAPSPCCPPSTPSKIWQRAGPAPRPPPPPSKTGTGPRKASEAQSHFLEGQPHSSAALRAAMTDSPAPITDTRKKQEEAALSPLPSPESHSHHAADFGDDWCASPQLLTAGDSAFLTLLDEAQHRGSENLKSSVDPVEEGEASRTVAADEKPSPPHPGIPPPSPSSEPSSPATPSYDLRCTAGRRQHRAAAQLETLRAASWPSGASPGPQTYEVELEMQASGLPKLRIKKVDPGSLSEAETLRGEESALPGLSIPRPSKSSGKPEATYLSPPCLRPSHSTPGKSRGQTYICQSCTPTRCPSSTPSPFQTDGVVPWTPSPKHSGKTTPDTIKDWPRRKRAVDCSLGPSAGRGEVSGDFPGGMWLLEPEGKEQGLGLSITKTPILGDFELGVCKLPDQSPLRDSVPKAEEAASWGQFGLGSRKRFLSAEGEAEGQAKRVCDEQKGDSEVTRSEETSPGTSARQLPSSGEDDEVFASGATPPPSYAVRSCLSASSLQALTHSPLLFQTKMPSSRGKDAREEDVEVFPSAAEDSPFSRALSRRRPISRTYTRKKLIS", "length": 1896 }, "evidence": [ { "id": "A0A8V0ZIL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZIL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7Z2Z1-1", "protein_name": "Treslin", "gene_name": "TICRR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACCHKVMLLLDTAGGAARHSRVRRAALRLLTYLSCRFGLARVHWAFKFFDSQGARSRPSRVSDFRELGSRSWEDFEEELEARLEDRAHLPGPAPRATHTHGALMETLLDYQWDRPEITSPTKPILRSSGRRLLDVESEAKEAEAALGGLVNAVFLLAPCPHSQRELLQFVSGCEAQAQRLPPTPKQVMEKLLPKRVREVMVARKITFYWVDTTEWSKLWESPDHLGYWTVCELLHHGGGTVLPSESFSWDFAQAGEMLLRSGIKLSSEPHLSPWISMLPTDATLNRLLYNSPEYEASFPRMEGMLFLPVEAGKEIQETWTVTLEPLAMHQRHFQKPVRIFLKGSVAQWSLPTSSTLGTDSWMLGSPEESTATQRLLFQQLVSRLTAEELHLVADVDPGEGRPPITGVISPLSASAMILTVCRTKEAEFQRHVLQTAVADSPRDTASLFSDVVDSILNQTHDSLADTASAASPVPEWAQQELGHTTPWSPAVVEKWFPFCNISGASSDLMESFGLLQAASANKEESSKTEGELIHCLAELYQRKSREESTIAHQEDSKKKRGVPRTPVRQKMNTMCRSLKMLNVARLNVKAQKLHPDGSPDVAGEKGIQKIPSGRTVDKLEDRGRTLRSSKPKDFKTEEELLSYIRENYQKTVATGEIMLYACARNMISTVKMFLKSKGTKELEVNCLNQVKSSLLKTSKSLRQNLGKKLDKEDKVRECQLQVFLRLEMCLQCPSINESTDDMEQVVEEVTDLLRMVCLTEDSAYLAEFLEEILRLYIDSIPKTLGNLYNSLGFVIPQKLAGVLPTDFFSDDSMTQENKSPLLSVPFLSSARRSVSGSPESDELQELRTRSAKKRRKNALIRHKSIAEVSQNLRQIEIPKVSKRATKKENSHPAPQQPSQPVKDTVQEVTKVRRNLFNQELLSPSKRSLKRGLPRSHSVSAVDGLEDKLDNFKKNKGYHKLLTKSVAETPVHKQISKRLLHRQIKGRSSDPGPDIGVVEESPEKGDEISLRRSPRIKQLSFSRTHSASFYSVSQPKSRSVQRVHSFQQDKSDQRENSPVQSIRSPKSLLFGAMSEMISPSEKGSARMKKRSRNTLDSEVPAAYQTPKKSHQKSLSFSKTTPRRISHTPQTPLYTPERLQKSPAKMTPTKQAAFKESLKDSSSPGHDSPLDSKITPQKRHTQAGEGTSLETKTPRTPKRQGTQPPGFLPNCTWPHSVNSSPESPSCPAPPTSSTAQPRRECLTPIRDPLRTPPRAAAFMGTPQNQTHQQPHVLRAARAEEPAQKLKDKAIKTPKRPGNSTVTSSPPVTPKKLFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATLDTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVEEGEGLRTADAEKSSLSHPGIPPSPPSCGPGSPLMPSRDVHCTTDGRQCQASAQLDNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEESFLPALSMPRASRSLSKPEPTYVSPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSPFQTDGVPWTPSPKHSGKTTPDIIKDWPRRKRAVGCGAGSSSGRGEVGADLPGSLSLLESEGKDHGLELSIHRTPILEDFELEGVCQLPDQSPPRNSMPKAEEASSWGQFGLSSRKRVLLAKEEADRGAKRICDLREDSEVSKSKEGSPSWSAWQLPSTGDEEVFVSGSTPPPSCAVRSCLSASALQALTQSPLLFQGKTPSSQSKDPRDEDVDVLPSTVEDSPFSRAFSRRRPISRTYTRKKLMGTWLEDL", "length": 1910 }, "evidence": [ { "id": "A0A8V0ZIL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZIL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BQ33-1", "protein_name": "Treslin", "gene_name": "Ticrr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACCHKVMLLVDTAGVSAPHSPARRAALRLLTYLSCRFGLARVHWTFKFFDSQGARSRPSRVSDFRELGSRSWEDFEEELEARLGDRPPGAHLPGPTPRATHTHGALMETLLDYQWDRPEITSPTKPILRSSGRRLLDADGEAREAQAALGGFGNAVFLLAPCPHSQRELLQFVSGCEAQAQRVPLTPKQVMEKVLPKRVQEVMIARNITLYWVDTTERSKLWASPDHVGYWTVCELLHHGGGTILPAETWSLGFTKARETVLPCGGELSHKPHPSPWISALPIDATVNCLLYNSEYEASFPRIEGTLFLPVQGKEIEETWAISLEPLAMHQRHFQKPVRIVLRGSVAQWSLPVSSALGTDSWMLQSPEEHRSTQRLLFQELVSRLTAEEFHLVASVDPGEGWPPITGIISPFSANAMILTVFRAKEAEFQSHFLQTAATEGSQDTASLFSDVVDSVLNQSHNLFEDPASSAPCVPEWVQQELSHTSSWSPALVEKWFPFSNASGATSDLMESFWLLHAASPDNDESSKTESELTRCLSELYQRSHEESTVVNQERSRKKRGIPRTPVRQKMNTMSRSLKMLNVARLNVKAQKLHPDGSPDTAVEKGLQKAVIGRTADKLEDRGRILRSSKLKEFKTEEELLAYIHDNYQKAVATEEITLYSCAQNMVSTIKMFLKSKDIKELEVACLSHVNSNLLKTSKTLRQNLAGKMDTEDKVGECQLQVFLRLEMCEQCPSVLDRPDEVERIVEEVTDLLRLVCLTKDSAYLSEFLEEILRLYIGSIPGTIGQLYHSLGLKIPQKLAGVLPTGFFSDDSMSQESMSPPPSSSTHRSVSAITESEQLEELRTRSAKKRRKNALIRHKSIAEISQTLRQIEVPKVSKRATRNENSHSASIQLPVPRKDTIQEVTKVRRNLFNQEMLSPSKRGLKKGLPRSHSVSALECLHHKQDKFKKTKSSTFQGYCKLLTKSVAETPVHKQISRRLLHRQIKGRSSDPGPDIHVVEESPEKEDEMTLRRSPRIKQLSFSRTNSGSFYSVSQPKSRSVQRIHSSQQESEQRENFPVQSIQSPKTLLFGALSEIPSSSKKGSAQIKRSLRSMLDSEISTSYETPKKSNQKSPSFSKTTPRRFPRTAQTLLYTPERLQNSPTEMTSAEGTISEATIKTPSSHGYNSPFASKVTSQKTVSPAKEETSPPLTKLPSTPRESDVQPPQCSSDCTWPHSVNSSPEGPYYPASPPPMAGQARSQCLTPIRYSFRTPPRTALAGTSKQQEHQELPLPRASQTQEPPQGLEKKALKIPKKPAHTSTSPLSPEEHYSGCDVSPHQPRNSLSASPPPGELNWKEHQTSPSVTSSVSCPVPSTPPRTPQRMTCPIPPSPPSKLRRSCRKKSCPPQDFPECHPGPSAAPVLSSATSPGAVTGSREEQSQFSEGQSYLGTGFRSDCHVSSPVLTASDTKCLPLIDEAQLHGLKNQEVKSGILPGEEGEEPESTIADELPSVSDPGILVPAPSSVSSSSELLPYPLCCTADGKQRQDAAQQGSPRASEATSSPQTYEVELEMQASGLPKLRIKKIDPGVLLEAEALGKEAPLGEEGALPALCMPKASKSSGRTEHPYLSPPCLRPSHSTPGKNGGQTFICQSCTPSRCPPSTPSPFQADAGVSWTPSPKQSGKTTPEIIKDWPRRKRAVDCSAGPSAGRGEASMDLPGSLSLLEPEPEGKERSLEQDLSKVLISEEFELEGVCQLPDQSPPKDSASVTEETSWGQFGLGRKRFLSAKEESEYKVKRVCDSLSEDPQASKQKECSPRWSALPLHSVGDDEVFVSGSTPPSGCMVRSCLSASGLQALTQSPLLFQGRTPSSHSTDTRDEEVDVFPSTAEESPFSHTLSRKRPFRTYTRKKLIS", "length": 1889 }, "evidence": [ { "id": "A0A8V0ZIL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZIL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" } ], "pmid": "" }, { "name": "response to ionizing radiation", "id": "GO:0010212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" } ], "pmid": "" }, { "name": "mitotic DNA replication checkpoint signaling", "id": "GO:0033314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033314", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" } ], "pmid": "" }, { "name": "regulation of DNA-templated DNA replication initiation", "id": "GO:0030174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030174", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1016, "end_pos": 1018, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1366, "end_pos": 1368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1381, "end_pos": 1383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1472, "end_pos": 1474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1519, "end_pos": 1521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1606, "end_pos": 1608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1670, "end_pos": 1672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1712, "end_pos": 1714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1739, "end_pos": 1741, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1766, "end_pos": 1768, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" }, { "id": "PF15292", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15292" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Treslin M", "eco_id": "ECO_0000259", "start_pos": 275, "end_pos": 415, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZIL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" }, { "id": "PF21854", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21854" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Treslin N-terminal", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 195, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZIL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL1" }, { "id": "PF21855", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21855" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Treslin STD", "eco_id": "ECO_0000259", "start_pos": 632, "end_pos": 782, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1016, "end_pos": 1018 }, { "start_pos": 1366, "end_pos": 1368 }, { "start_pos": 1381, "end_pos": 1383 }, { "start_pos": 1472, "end_pos": 1474 }, { "start_pos": 1519, "end_pos": 1521 }, { "start_pos": 1606, "end_pos": 1608 }, { "start_pos": 1670, "end_pos": 1672 }, { "start_pos": 1712, "end_pos": 1714 }, { "start_pos": 1739, "end_pos": 1741 }, { "start_pos": 1766, "end_pos": 1768 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIQ1-1", "uniprot_ac": "A0A8V0ZIQ1", "uniprot_id": "A0A8V0ZIQ1_CHICK", "mass": { "chemical_mass": 27454.0, "monoisotopic_mass": 27454.0 }, "refseq": { "ac": "NP_001376310", "name": "myeloid leukemia factor 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376310" }, "gene_names": [ { "name": "MLF2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1" } ] }, { "name": "MLF2", "type": "synonym", "evidence": [ { "id": "NP_001376310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376310" } ] } ], "protein_names": [ { "name": "Myeloid leukemia factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1/entry#names_and_taxonomy" } ] }, { "name": "myeloid leukemia factor 2", "type": "synonym", "evidence": [ { "id": "NP_001376310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376310" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01008342.1, BU408802.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06140853, SAMN06143078 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000015.1. On Dec 17, 2020 this sequence version replaced XP_015148853.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376310" } ] }, { "annotation": "These results suggest that the single nucleotide polymorphism in the MLF2 gene can be one of the markers to select coccidiosis resistance in chickens.", "evidence": [ { "database": "RefSeq", "id": "NP_001376310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376310" }, { "database": "PubMed", "id": "20008798", "url": "https://glygen.org/publication/PubMed/20008798" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MLF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1", "locus": { "chromosome": "1", "start_pos": 77113956, "end_pos": 77122963, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021530", "url": "https://www.ensembl.org/id/ENSGALG00010021530" } ] } } ], "crossref": [ { "id": "A0A8V0ZIQ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIQ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "418284", "url": "https://www.ncbi.nlm.nih.gov/gene/418284", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FDNEWRR", "url": "https://omabrowser.org/oma/group/FDNEWRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD72", "url": "https://www.orthodb.org/?gene=A0A8V0ZD72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIQ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKD3", "url": "https://www.orthodb.org/?gene=A0A8V0ZKD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR43", "url": "https://www.orthodb.org/?gene=A0A8V0ZR43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001376310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRLMRDGEPEDPMFAMDPFAIHRQHMNRMLSGSFGFGPLLGITDGTTPGARQAGRRMQAGAVSPFGMLGMAGGFIDMFGMMNDMIGNMEHMTSGANCQTFTSSTVISYSNLGDGPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRERAHIMQRSRNHRTGDQEERQDYINMDESDAAAFDDEWRRETSRFRPQRGLEYRRHEGSSRRAEGTRLAIQGPEDSPSRQSRRYDW", "length": 242, "header": "tr|A0A8V0ZIQ1-1|A0A8V0ZIQ1_CHICK Isoform 1 of Myeloid leukemia factor 2 OS=Gallus gallus OX=9031 GN=MLF2 PE=1 SV=1 CANONICAL=A0A8V0ZIQ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1/entry#A0A8V0ZD72-1", "sequence": { "sequence": "MFRLMRDGEPEDPMFAMDPFAIHRQHMNRMLSGSFGFGPLLGITDGTTPGARQAGRRMQVREGLTTGGFIDMFGMMNDMIGNMEHMTSGANCQTFTSSTVISYSNLGDGPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRERAHIMQRSRNHRTGDQEERQDYINMDESDAAAFDDEWRRETSRFRPQRGLEYRRHEGSSRRAEGTRLAIQGPEDSPSRQSRRYDW", "length": 236, "header": "tr|A0A8V0ZD72-1|A0A8V0ZIQ1_CHICK Computationally mapped isoform of Myeloid leukemia factor 2 OS=Gallus gallus OX=9031 GN=MLF2 PE=1 SV=1 CANONICAL=A0A8V0ZIQ1-1" }, "locus": { "chromosome": "1", "start_pos": 77121350, "end_pos": 77115692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052277.1", "url": "https://www.ensembl.org/id/ENSGALT00010052277.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031233.1", "url": "https://www.ensembl.org/id/ENSGALP00010031233.1" } ] } }, { "isoform_ac": "A0A8V0ZIQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1/entry#A0A8V0ZIQ1-1", "sequence": { "sequence": "MFRLMRDGEPEDPMFAMDPFAIHRQHMNRMLSGSFGFGPLLGITDGTTPGARQAGRRMQAGAVSPFGMLGMAGGFIDMFGMMNDMIGNMEHMTSGANCQTFTSSTVISYSNLGDGPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRERAHIMQRSRNHRTGDQEERQDYINMDESDAAAFDDEWRRETSRFRPQRGLEYRRHEGSSRRAEGTRLAIQGPEDSPSRQSRRYDW", "length": 242, "header": "tr|A0A8V0ZIQ1-1|A0A8V0ZIQ1_CHICK Isoform 1 of Myeloid leukemia factor 2 OS=Gallus gallus OX=9031 GN=MLF2 PE=1 SV=1 CANONICAL=A0A8V0ZIQ1-1" }, "locus": { "chromosome": "1", "start_pos": 77121350, "end_pos": 77115692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052274.1", "url": "https://www.ensembl.org/id/ENSGALT00010052274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031230.1", "url": "https://www.ensembl.org/id/ENSGALP00010031230.1" } ] } }, { "isoform_ac": "A0A8V0ZKD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1/entry#A0A8V0ZKD3-1", "sequence": { "sequence": "MREANRLERKGRAGCEPPWESGRERPASSSFSSSSSSFSCRRPLGTARRACRQGKGHGRDPFAIHRQHMNRMLSGSFGFGPLLGITDGTTPGARQAGRRMQAGAVSPFGMLGMAGGFIDMFGMMNDMIGNMEHMTSGANCQTFTSSTVISYSNLGDGPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRERAHIMQRSRNHRTGDQEERQDYINMDESDAAAFDDEWRRETSRFRPQRGLEYRRHEGSSRRAEGTRLAIQGPEDSPSRQSRRYDW", "length": 284, "header": "tr|A0A8V0ZKD3-1|A0A8V0ZKD3_CHICK Computationally mapped isoform of Myeloid leukemia factor 2 OS=Gallus gallus OX=9031 GN=MLF2 PE=1 SV=1 CANONICAL=A0A8V0ZIQ1-1" }, "locus": { "chromosome": "1", "start_pos": 77121700, "end_pos": 77115692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052255.1", "url": "https://www.ensembl.org/id/ENSGALT00010052255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031216.1", "url": "https://www.ensembl.org/id/ENSGALP00010031216.1" } ] } }, { "isoform_ac": "A0A8V0ZR43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1/entry#A0A8V0ZR43-1", "sequence": { "sequence": "MALCPGERALVATSCLAQLPASSASARSPGPVRACARRTGWSGRGERGASRHGSPGVSGPRLPRSPLPPHLFPAVVPSAPPGAPAGRGRGTAEPAPVEGSSMFRLMRDGEPEDPMFAMDPFAIHRQHMNRMLSGSFGFGPLLGITDGTTPGARQAGRRMQAGAVSPFGMLGMAGGFIDMFGMMNDMIGNMEHMTSGANCQTFTSSTVISYSNLGDGPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRERAHIMQRSRNHRTGDQEERQDYINMDESDAAAFDDEWRRETSRFRPQRGLEYRRHEGSSRRAEGTRLAIQGPEDSPSRQSRRYDW", "length": 343, "header": "tr|A0A8V0ZR43-1|A0A8V0ZR43_CHICK Computationally mapped isoform of Myeloid leukemia factor 2 OS=Gallus gallus OX=9031 GN=MLF2 PE=1 SV=1 CANONICAL=A0A8V0ZIQ1-1" }, "locus": { "chromosome": "1", "start_pos": 77121801, "end_pos": 77115692, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052268.1", "url": "https://www.ensembl.org/id/ENSGALT00010052268.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031224.1", "url": "https://www.ensembl.org/id/ENSGALP00010031224.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Genetic effects analysis of myeloid leukemia factor 2 and T cell receptor-beta on resistance to coccidiosis in chickens.", "journal": "Poultry science", "date": "2010-01", "authors": "Kim E-S, Hong Y H, Lillehoj H S", "evidence": [ { "database": "RefSeq", "id": "NP_001376310", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376310" } ], "reference": [ { "type": "PubMed", "id": "20008798", "url": "https://glygen.org/publication/PubMed/20008798" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LWT5-1", "protein_name": "Myeloid leukemia factor 2", "gene_name": "Mlf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMGKKEKKGWGGTREKQPSGDEDGRSGGEGEEPRSSLPGESCLHLRIPNRLAEESVEPPGAEIRMFRFMRDVEPEDPMFLMDPFAIHRQHMSRMLSGGFGYSPFLSITDGNMPATRPASRRMQAGAVSPFGMLGMSGGFMDMFGMMNDMIGNMEHMAAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSRYRQQRPLEFRRHEASVGGGRRAEGPPRLAIQGPEDSPSRQSRRYDW", "length": 312 }, "evidence": [ { "id": "A0A8V0ZIQ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZIQ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15773-1", "protein_name": "Myeloid leukemia factor 2", "gene_name": "MLF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFRFMRDVEPEDPMFLMDPFAIHRQHMSRMLSGGFGYSPFLSITDGNMPGTRPASRRMQQAGAVSPFGMLGMSGGFMDMFGMMNDMIGNMEHMTAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSRFRQQRPLEFRRLESSGAGGRRAEGPPRLAIQGPEDSPSRQSRRYDW", "length": 248 }, "evidence": [ { "id": "A0A8V0ZIQ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZIQ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99KX1-1", "protein_name": "Myeloid leukemia factor 2", "gene_name": "Mlf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFRFMRDVEPEDPMFLMDPFAIHRQHMSRMLSGGFGYSPFLSITDGNMPATRPASRRMQAGAVSPFGMLGMSGGFMDMFGMMNDMIGNMEHMAAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSRYRQQRPLEFRRHEASVGGGRRAEGPPRLAIQGPEDSPSRQSRRYDW", "length": 247 }, "evidence": [ { "id": "A0A8V0ZIQ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZIQ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIU3-1", "uniprot_ac": "A0A8V0ZIU3", "uniprot_id": "A0A8V0ZIU3_CHICK", "mass": { "chemical_mass": 84754.0, "monoisotopic_mass": 84754.0 }, "refseq": { "ac": "XP_046798942", "name": "uncharacterized protein DUSP11RC1I isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798942" }, "gene_names": [ { "name": "DUSP11RC1I", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3" } ] }, { "name": "DUSP11RC1I", "type": "synonym", "evidence": [ { "id": "XP_046798942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798942" } ] } ], "protein_names": [ { "name": "RNA/RNP complex-1-interacting phosphatase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3/entry#names_and_taxonomy" } ] }, { "name": "Dual specificity protein phosphatase 11", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3/entry#names_and_taxonomy" } ] }, { "name": "Phosphatase that interacts with RNA/RNP complex 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein DUSP11RC1I isoform X6", "type": "synonym", "evidence": [ { "id": "XP_046798942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798942" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046798942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798942" } ] }, { "annotation": "Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro). Binds to RNA. May participate in nuclear mRNA metabolism.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT9#function" }, { "database": "UniProtKB", "id": "ARBA00054725", "url": "https://www.uniprot.org/uniprotkb/ARBA00054725#function" }, { "database": "UniProtKB", "id": "A0A8V0ZIU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DUSP11RC1I", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZIU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "423818", "url": "https://www.ncbi.nlm.nih.gov/gene/423818", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423818", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423818", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SFHDYES", "url": "https://omabrowser.org/oma/group/SFHDYES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD98", "url": "https://www.orthodb.org/?gene=A0A8V0ZD98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIT9", "url": "https://www.orthodb.org/?gene=A0A8V0ZIT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIU3", "url": "https://www.orthodb.org/?gene=A0A8V0ZIU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKI0", "url": "https://www.orthodb.org/?gene=A0A8V0ZKI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKI5", "url": "https://www.orthodb.org/?gene=A0A8V0ZKI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10367", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10367", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10367:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10367:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046798942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046798942", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNRRLPARPRGAGAMPPPGKLAGRRACAVETLSGTFRAACLAPAFLCKGNPVRCALSPLSPALPAPAFSMVKKNTIPEGWRSLTPVGQPIPGTRFIAFKVPLKGAINQRLTPTQKFTPKDLIAAMKALNVELGLIIDLTYTTRYYEVKDLPKSVQYKKLYTVGLEVPDNATILQFKKWVRKFLWENARNEKLIGVHCTNGINRTGYLICRYLIDVEGWDPEAAIQAFGDARGHCMDGLVYLTDLRTQPMRSNLGMDVWDSDEDIIPPPNATEGPVEQFPNEDFQGSGKRLRVYDDNSHNNLQGQTQLRDFDFINKGPGRRRRPFHDHQTQDDLRAPMQMRNWDYNRGPGQRQRPFPDHQFYDDYREDMQLKDLDFSNKGPGQQLRPFYGRQFRGDLQTDRQSRNFEFKRGRGQRQRSFPDCPSHNDSQEAMKSKGFGSRGRGQRQRLFHSHQSHDQFQAPVQLKELDCVNKGAGQRLRPFHDYQSHDDLQPQMQLEDFEFVNRGHGQRLRPFHDHQPHNDLQTEMQLKDYDNKGPGQRRRPFHDHQPYDDLQEQPQLKDFDYVNKGQGQKRSRPFHDHPVQDELPREWCSDRSQSFSSHENVSEPQFSSSPSLHRDYRSDNDDFSRSYSSRASGPEDSRRVHPSDEFNKGKNRFAPYSSCTMHPSSSVHQQDSSLDYEIKTFEGETSREMEQGKRLPVVTVDYNYGLPLDYGPEEKERTPYDLPPRDHYSWN", "length": 733, "header": "tr|A0A8V0ZIU3-1|A0A8V0ZIU3_CHICK Isoform 1 of RNA/RNP complex-1-interacting phosphatase OS=Gallus gallus OX=9031 GN=DUSP11RC1I PE=3 SV=1 CANONICAL=A0A8V0ZIU3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3/entry#A0A8V0ZD98-1", "sequence": { "sequence": "MKALNVELGLIIDLTYTTRYYEVKDLPKSVQYKKLYTVGLEVPDNATILQFKKWVRKFLWENARNEKLIGVHCTNGINRTGYLICRYLIDVEGWDPEAAIQAFGDARGHCMDGLVYLTDLRTQPMRSNLGMDVWDSDEDIIPPPNATEGPVEQFPNEDFQGSGKRLRVYDDNSHNNLQGQTQLRDFDFINKGPGRRRRPFHDHQTQDDLRAPMQMRNWDYNRGPGQRQRPFPDHQFYDDYREDMQLKDLDFSNKGPGQQLRPFYGRQFRGDLQTDRQSRNFEFKRGRGQRQRSFPDCPSHNDSQEAMKSKGFGSRGRGQRQRLFHSHQSHDQFQAPVQLKELDCVNKGAGQRLRPFHDYQSHDDLQPQMQLEDFEFVNRGHGQRLRPFHDHQPHNDLQTEMQLKDYDNKGPGQRRRPFHDHQPYDDLQEQPQLKDFDYVNKGQGQKRSRPFHDHPVQDELPREWCSDSSRASGPEDSRRVHPSDEFNKGKNRFAPYSSCTMHPSSSVHQQDSSLDYEIKTFEGETSREMEQGKRLPVVTVDYNYGLPLDYGPEEKERTPYDLPPRDHYSWN", "length": 571, "header": "tr|A0A8V0ZD98-1|A0A8V0ZIU3_CHICK Computationally mapped isoform of RNA/RNP complex-1-interacting phosphatase OS=Gallus gallus OX=9031 GN=DUSP11RC1I PE=3 SV=1 CANONICAL=A0A8V0ZIU3-1" }, "locus": { "chromosome": "6", "start_pos": 21806975, "end_pos": 21798167, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052320.1", "url": "https://www.ensembl.org/id/ENSGALT00010052320.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031258.1", "url": "https://www.ensembl.org/id/ENSGALP00010031258.1" } ] } }, { "isoform_ac": "A0A8V0ZIT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3/entry#A0A8V0ZIT9-1", "sequence": { "sequence": "MVKKNTIPEGWRSLTPVGQPIPGTRFIAFKVPLKGAINQRLTPTQKFTPKDLIAAMKALNVELGLIIDLTYTTRYYEVKDLPKSVQYKKLYTVGLEVPDNATILQFKKWVRKFLWENARNEKLIGVHCTNGINRTGYLICRYLIDVEGWDPEAAIQAFGDARGHCMDGLVYLTDLRTQPMRSNLGMDVWDSDEDIIPPPNATEGPVEQFPNEDFQGSGKRLRVYDDNSHNNLQGQTQLRDFDFINKGPGRRRRPFHDHQTQDDLRAPMQMRNWDYNRGPGQRQRPFPDHQFYDDYREDMQLKDLDFSNKGPGQQLRPFYGRQFRGDLQTDRQSRNFEFKRGRGQRQRSFPDCPSHNDSQEAMKSKGFGSRGRGQRQRLFHSHQSHDQFQAPVQLKELDCVNKGAGQRLRPFHDYQSHDDLQPQMQLEDFEFVNRGHGQRLRPFHDHQPHNDLQTEMQLKDYDNKGPGQRRRPFHDHQPYDDLQEQPQLKDFDYVNKGQGQKRSRPFHDHPVQDELPREWCSDRSQSFSSHENVSEPQFSSSPSLHRDYRSDNDDFSRSYSSRASGPEDSRRVHPSDEFNKGKNRFAPYSSCTMHPSSSVHQQDSSLDYEIKTFEGETSREMEQGKRLPVVTVDYNYGLPLDYGPEEKERTPYDLPPRDHYSWN", "length": 663, "header": "tr|A0A8V0ZIT9-1|A0A8V0ZIT9_CHICK Computationally mapped isoform of RNA/RNP complex-1-interacting phosphatase OS=Gallus gallus OX=9031 GN=DUSP11RC1I PE=3 SV=1 CANONICAL=A0A8V0ZIU3-1" }, "locus": { "chromosome": "6", "start_pos": 21816260, "end_pos": 21798167, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052335.1", "url": "https://www.ensembl.org/id/ENSGALT00010052335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031270.1", "url": "https://www.ensembl.org/id/ENSGALP00010031270.1" } ] } }, { "isoform_ac": "A0A8V0ZIU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3/entry#A0A8V0ZIU3-1", "sequence": { "sequence": "MRNRRLPARPRGAGAMPPPGKLAGRRACAVETLSGTFRAACLAPAFLCKGNPVRCALSPLSPALPAPAFSMVKKNTIPEGWRSLTPVGQPIPGTRFIAFKVPLKGAINQRLTPTQKFTPKDLIAAMKALNVELGLIIDLTYTTRYYEVKDLPKSVQYKKLYTVGLEVPDNATILQFKKWVRKFLWENARNEKLIGVHCTNGINRTGYLICRYLIDVEGWDPEAAIQAFGDARGHCMDGLVYLTDLRTQPMRSNLGMDVWDSDEDIIPPPNATEGPVEQFPNEDFQGSGKRLRVYDDNSHNNLQGQTQLRDFDFINKGPGRRRRPFHDHQTQDDLRAPMQMRNWDYNRGPGQRQRPFPDHQFYDDYREDMQLKDLDFSNKGPGQQLRPFYGRQFRGDLQTDRQSRNFEFKRGRGQRQRSFPDCPSHNDSQEAMKSKGFGSRGRGQRQRLFHSHQSHDQFQAPVQLKELDCVNKGAGQRLRPFHDYQSHDDLQPQMQLEDFEFVNRGHGQRLRPFHDHQPHNDLQTEMQLKDYDNKGPGQRRRPFHDHQPYDDLQEQPQLKDFDYVNKGQGQKRSRPFHDHPVQDELPREWCSDRSQSFSSHENVSEPQFSSSPSLHRDYRSDNDDFSRSYSSRASGPEDSRRVHPSDEFNKGKNRFAPYSSCTMHPSSSVHQQDSSLDYEIKTFEGETSREMEQGKRLPVVTVDYNYGLPLDYGPEEKERTPYDLPPRDHYSWN", "length": 733, "header": "tr|A0A8V0ZIU3-1|A0A8V0ZIU3_CHICK Isoform 1 of RNA/RNP complex-1-interacting phosphatase OS=Gallus gallus OX=9031 GN=DUSP11RC1I PE=3 SV=1 CANONICAL=A0A8V0ZIU3-1" }, "locus": { "chromosome": "6", "start_pos": 21817239, "end_pos": 21798167, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052342.1", "url": "https://www.ensembl.org/id/ENSGALT00010052342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031275.1", "url": "https://www.ensembl.org/id/ENSGALP00010031275.1" } ] } }, { "isoform_ac": "A0A8V0ZKI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3/entry#A0A8V0ZKI0-1", "sequence": { "sequence": "MKALNVELGLIIDLTYTTRYYEVKDLPKSVQYKKLYTVGLEVPDNATILQFKKWVRKFLWENARNEKLIGVHCTNGINRTGYLICRYLIDVEGWDPEAAIQAFGDARGHCMDGLVYLTDLRTQPMRSNLGMDVWDSDEDIIPPPNATEGPVEQFPNEDFQGSGKRLRVYDDNSHNNLQGQTQLRDFDFINKGPGRRRRPFHDHQTQDDLRAPMQMRNWDYNRGPGQRQRPFPDHQFYDDYREDMQLKDLDFSNKGPGQQLRPFYGRQFRGDLQTDRQSRNFEFKRGRGQRQRSFPDCPSHNDSQEAMKSKGFGSRGRGQRQRLFHSHQSHDQFQAPVQLKELDCVNKGAGQRLRPFHDYQSHDDLQPQMQLEDFEFVNRGHGQRLRPFHDHQPHNDLQTEMQLKDYDNKGPGQRRRPFHDHQPYDDLQEQPQLKDFDYVNKGQGQKRSRPFHDHPVQDELPREWCSDRDYRSDNDDFSRSYSSRASGPEDSRRVHPSDEFNKGKNRFAPYSSCTMHPSSSVHQQDSSLDYEIKTFEGETSREMEQGKRLPVVTVDYNYGLPLDYGPEEKERTPYDLPPRDHYSWN", "length": 585, "header": "tr|A0A8V0ZKI0-1|A0A8V0ZKI0_CHICK Computationally mapped isoform of Tyrosine specific protein phosphatases domain-containing protein OS=Gallus gallus OX=9031 GN=DUSP11RC1I PE=4 SV=1 CANONICAL=A0A8V0ZIU3-1" }, "locus": { "chromosome": "6", "start_pos": 21806975, "end_pos": 21798167, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052323.1", "url": "https://www.ensembl.org/id/ENSGALT00010052323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031261.1", "url": "https://www.ensembl.org/id/ENSGALP00010031261.1" } ] } }, { "isoform_ac": "A0A8V0ZKI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3/entry#A0A8V0ZKI5-1", "sequence": { "sequence": "MEEFDTSWAAYTRNQIYCIQSTFKRGTERWLRLLHLFCHSIGGDRACVKRLSQWTAHYSEKIQFCARGIFIPRAENTFQKPQLHRAINQRLTPTQKFTPKDLIAAMKALNVELGLIIDLTYTTRYYEVKDLPKSVQYKKLYTVGLEVPDNATILQFKKWVRKFLWENARNEKLIGVHCTNGINRTGYLICRYLIDVEGWDPEAAIQAFGDARGHCMDGLVYLTDLRTQPMRSNLGMDVWDSDEDIIPPPNATEGPVEQFPNEDFQGSGKRLRVYDDNSHNNLQGQTQLRDFDFINKGPGRRRRPFHDHQTQDDLRAPMQMRNWDYNRGPGQRQRPFPDHQFYDDYREDMQLKDLDFSNKGPGQQLRPFYGRQFRGDLQTDRQSRNFEFKRGRGQRQRSFPDCPSHNDSQEAMKSKGFGSRGRGQRQRLFHSHQSHDQFQAPVQLKELDCVNKGAGQRLRPFHDYQSHDDLQPQMQLEDFEFVNRGHGQRLRPFHDHQPHNDLQTEMQLKDYDNKGPGQRRRPFHDHQPYDDLQEQPQLKDFDYVNKGQGQKRSRPFHDHPVQDELPREWCSDRSQSFSSHENVSEPQFSSSPSLHRDYRSDNDDFSRSYSSRASGPEDSRRVHPSDEFNKGKNRFAPYSSCTMHPSSSVHQQDSSLDYEIKTFEGETSREMEQGKRLPVVTVDYNYGLPLDYGPEEKERTPYDLPPRDHYSWN", "length": 713, "header": "tr|A0A8V0ZKI5-1|A0A8V0ZKI5_CHICK Computationally mapped isoform of Tyrosine specific protein phosphatases domain-containing protein OS=Gallus gallus OX=9031 GN=DUSP11RC1I PE=4 SV=1 CANONICAL=A0A8V0ZIU3-1" }, "locus": { "chromosome": "6", "start_pos": 21810300, "end_pos": 21798167, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052328.1", "url": "https://www.ensembl.org/id/ENSGALT00010052328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031266.1", "url": "https://www.ensembl.org/id/ENSGALP00010031266.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423818", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423818", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3" } ], "pmid": "" }, { "name": "polynucleotide 5'-phosphatase activity", "id": "GO:0004651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004651", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3" } ], "pmid": "" }, { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU3" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 232, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 602, "end_pos": 604 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFF0-1", "uniprot_ac": "A0A8V0ZFF0", "uniprot_id": "A0A8V0ZFF0_CHICK", "mass": { "chemical_mass": 20847.0, "monoisotopic_mass": 20847.0 }, "refseq": {}, "gene_names": [ { "name": "EXOSC1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF0" } ] } ], "protein_names": [ { "name": "Exosome complex component CSL4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF0/entry#names_and_taxonomy" } ] }, { "name": "Exosome component 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXOSC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF0", "locus": { "chromosome": "6", "start_pos": 23140437, "end_pos": 23138740, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020705", "url": "https://www.ensembl.org/id/ENSGALG00010020705" } ] } } ], "crossref": [ { "id": "A0A8V0ZFF0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05791", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05791", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039771", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039771", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEA9", "url": "https://www.orthodb.org/?gene=A0A8V0ZEA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFF0", "url": "https://www.orthodb.org/?gene=A0A8V0ZFF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12686", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12686", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12686:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12686:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-429958", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429958", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-450385", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450385", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9930044", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9930044", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZEA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VLALSERPAGERLCSTEEASAGSGTYARHGSIFASLAGCLQRCAEGGGLPVVSVVRDAEAQLLPGVGAVVTCKVCSINSRFAKVNILYVGSTPLKSTFRGTIRREDIRATEKDKVEVYKSFRPGDIVLAKVISLGDAQSNYLLSTAENELGVVVARSEAGVQMVPISWCEMQCPQTHTKDFRKVARVQPQFLQT", "length": 194, "header": "tr|A0A8V0ZFF0-1|A0A8V0ZFF0_CHICK Isoform 1 of Exosome complex component CSL4 OS=Gallus gallus OX=9031 GN=EXOSC1 PE=1 SV=1 CANONICAL=A0A8V0ZFF0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF0/entry#A0A8V0ZEA9-1", "sequence": { "sequence": "PARWVPGLGRPLACPCACLRPGSAPSLQSSAWRAAPGAAGKERCGALNEPPGPAHAALTARCPSVQVCSINSRFAKVNILYVGSTPLKSTFRGTIRREDIRATEKDKVEVYKSFRPGDIVLAKVISLGDAQSNYLLSTAENELGVVVARSEAGVQMVPISWCEMQCPQTHTKDFRKVARVQPQFLQT", "length": 187, "header": "tr|A0A8V0ZEA9-1|A0A8V0ZFF0_CHICK Computationally mapped isoform of Exosome complex component CSL4 OS=Gallus gallus OX=9031 GN=EXOSC1 PE=1 SV=1 CANONICAL=A0A8V0ZFF0-1" }, "locus": { "chromosome": "6", "start_pos": 23140288, "end_pos": 23139141, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050028.1", "url": "https://www.ensembl.org/id/ENSGALT00010050028.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029556.1", "url": "https://www.ensembl.org/id/ENSGALP00010029556.1" } ] } }, { "isoform_ac": "A0A8V0ZFF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF0/entry#A0A8V0ZFF0-1", "sequence": { "sequence": "VLALSERPAGERLCSTEEASAGSGTYARHGSIFASLAGCLQRCAEGGGLPVVSVVRDAEAQLLPGVGAVVTCKVCSINSRFAKVNILYVGSTPLKSTFRGTIRREDIRATEKDKVEVYKSFRPGDIVLAKVISLGDAQSNYLLSTAENELGVVVARSEAGVQMVPISWCEMQCPQTHTKDFRKVARVQPQFLQT", "length": 194, "header": "tr|A0A8V0ZFF0-1|A0A8V0ZFF0_CHICK Isoform 1 of Exosome complex component CSL4 OS=Gallus gallus OX=9031 GN=EXOSC1 PE=1 SV=1 CANONICAL=A0A8V0ZFF0-1" }, "locus": { "chromosome": "6", "start_pos": 23140288, "end_pos": 23138835, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050023.1", "url": "https://www.ensembl.org/id/ENSGALT00010050023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029552.1", "url": "https://www.ensembl.org/id/ENSGALP00010029552.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-429958", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429958", "resource": "Reactome", "description": "mRNA decay by 3' to 5' exoribonuclease" }, { "id": "R-GGA-450385", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-450385", "resource": "Reactome", "description": "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" }, { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" }, { "id": "R-GGA-9930044", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9930044", "resource": "Reactome", "description": "Nuclear RNA decay" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, 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domain containing 10", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFU2/entry#names_and_taxonomy" } ] }, { "name": "sterile alpha motif domain-containing protein 13 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015146305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146305" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015146305.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146305" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFU2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "THAP10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFU2", "locus": { "chromosome": "8", "start_pos": 16352508, "end_pos": 16364353, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020742", "url": "https://www.ensembl.org/id/ENSGALG00010020742" } ] } } ], "crossref": [ { "id": "A0A8V0ZFU2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09583", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09583", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424541", "url": "https://www.ncbi.nlm.nih.gov/gene/424541", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEH0", "url": "https://www.orthodb.org/?gene=A0A8V0ZEH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFK5", "url": "https://www.orthodb.org/?gene=A0A8V0ZFK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFT6", "url": "https://www.orthodb.org/?gene=A0A8V0ZFT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFU2", "url": "https://www.orthodb.org/?gene=A0A8V0ZFU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLW4", "url": "https://www.orthodb.org/?gene=A0A8V0ZLW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146305", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVRWCTRVTQRPPGAPRCGRGRGSSVPARSPAAVGVPSPGLRRAAAAGSAECSGLSVEGASSPPVWCCSLVLLLRKPLFSMLTVDMENKENGSLDVKNSVENGRPPDPADWAVIDVVNYFRTAGFEEQASAFQEQEIDGKSLLLMTRNDVLTGLSLKLGPALKIYEYHVKPLQTQHLKNNSL", "length": 183, "header": "tr|A0A8V0ZFU2-1|A0A8V0ZFU2_CHICK Isoform 1 of THAP domain containing 10 OS=Gallus gallus OX=9031 GN=THAP10 PE=4 SV=1 CANONICAL=A0A8V0ZFU2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFU2/entry#A0A8V0ZEH0-1", "sequence": { "sequence": "MVLWMSRRRSVSLVPGIRSSKWNRKAVILLYWSGGSSVENGRPPDPADWAVIDVVNYFRTAGFEEQASAFQEQEIDGKSLLLMTRNDVLTGLSLKLGPALKIYEYHVKPLQTQHLKNNSL", "length": 120, "header": "tr|A0A8V0ZEH0-1|A0A8V0ZFU2_CHICK Computationally mapped isoform of THAP domain containing 10 OS=Gallus gallus OX=9031 GN=THAP10 PE=4 SV=1 CANONICAL=A0A8V0ZFU2-1" }, "locus": { "chromosome": "8", "start_pos": 16362949, "end_pos": 16353520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050154.1", "url": "https://www.ensembl.org/id/ENSGALT00010050154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029632.1", "url": "https://www.ensembl.org/id/ENSGALP00010029632.1" } ] } }, { "isoform_ac": "A0A8V0ZFK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFU2/entry#A0A8V0ZFK5-1", "sequence": { "sequence": "MQGRSVSLVPGIRSSKWNRKAVILLYWSGGSSVENGRPPDPADWAVIDVVNYFRTAGFEEQASAFQEQEIDGKSLLLMTRNDVLTGLSLKLGPALKIYEYHVKPLQTQHLKNNSL", "length": 115, "header": "tr|A0A8V0ZFK5-1|A0A8V0ZFK5_CHICK Computationally mapped isoform of THAP domain containing 10 OS=Gallus gallus OX=9031 GN=THAP10 PE=4 SV=1 CANONICAL=A0A8V0ZFU2-1" }, "locus": { "chromosome": "8", "start_pos": 16359977, "end_pos": 16353520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050145.1", "url": "https://www.ensembl.org/id/ENSGALT00010050145.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029629.1", "url": "https://www.ensembl.org/id/ENSGALP00010029629.1" } ] } }, { "isoform_ac": "A0A8V0ZFT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFU2/entry#A0A8V0ZFT6-1", "sequence": { "sequence": "IFIYFFSEGRSVSLVPGIRSSKWNRKAVILLYWSGGSSVENGRPPDPADWAVIDVVNYFRTAGFEEQASAFQEQEIDGKSLLLMTRNDVLTGLSLKLGPALKIYEYHVKPLQTQHLKNNSL", "length": 121, "header": "tr|A0A8V0ZFT6-1|A0A8V0ZFT6_CHICK Computationally mapped isoform of THAP domain containing 10 OS=Gallus gallus OX=9031 GN=THAP10 PE=4 SV=1 CANONICAL=A0A8V0ZFU2-1" }, "locus": { "chromosome": "8", "start_pos": 16359520, "end_pos": 16353520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050143.1", "url": "https://www.ensembl.org/id/ENSGALT00010050143.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029628.1", "url": "https://www.ensembl.org/id/ENSGALP00010029628.1" } ] } }, { "isoform_ac": "A0A8V0ZFU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFU2/entry#A0A8V0ZFU2-1", "sequence": { "sequence": "MLVRWCTRVTQRPPGAPRCGRGRGSSVPARSPAAVGVPSPGLRRAAAAGSAECSGLSVEGASSPPVWCCSLVLLLRKPLFSMLTVDMENKENGSLDVKNSVENGRPPDPADWAVIDVVNYFRTAGFEEQASAFQEQEIDGKSLLLMTRNDVLTGLSLKLGPALKIYEYHVKPLQTQHLKNNSL", "length": 183, "header": "tr|A0A8V0ZFU2-1|A0A8V0ZFU2_CHICK Isoform 1 of THAP domain containing 10 OS=Gallus gallus OX=9031 GN=THAP10 PE=4 SV=1 CANONICAL=A0A8V0ZFU2-1" }, "locus": { "chromosome": "8", "start_pos": 16364140, "end_pos": 16353520, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050156.1", "url": "https://www.ensembl.org/id/ENSGALT00010050156.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029633.1", "url": "https://www.ensembl.org/id/ENSGALP00010029633.1" } ] } }, { "isoform_ac": "A0A8V0ZLW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFU2/entry#A0A8V0ZLW4-1", "sequence": { "sequence": "MLVRWCTRVTQRPPGAPRCGRGRGSSVPARSPAAVGVPSPGLRRAAAAGSAECSGLSVEGASSPPVWCCSLVLLLRKPLFSMLTVDMENKENGSLDVKNSVENGRPPDPADWAVIDVVNYFRTAGFEEQASAFQEQASQEVGHTG", "length": 145, "header": "tr|A0A8V0ZLW4-1|A0A8V0ZLW4_CHICK Computationally mapped isoform of THAP domain containing 10 OS=Gallus gallus OX=9031 GN=THAP10 PE=4 SV=1 CANONICAL=A0A8V0ZFU2-1" }, "locus": { "chromosome": "8", "start_pos": 16364140, "end_pos": 16356303, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050150.1", "url": "https://www.ensembl.org/id/ENSGALT00010050150.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029631.1", "url": "https://www.ensembl.org/id/ENSGALP00010029631.1" } ] } } ], "glycosylation": [], 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"cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 180, "end_pos": 182 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFV5-1", "uniprot_ac": "A0A8V0ZFV5", "uniprot_id": "A0A8V0ZFV5_CHICK", "mass": { "chemical_mass": 32560.0, "monoisotopic_mass": 32560.0 }, "refseq": {}, "gene_names": [ { "name": "SLC25A20", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5" } ] } ], "protein_names": [ { "name": "Mitochondrial carnitine/acylcarnitine carrier protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5/entry#names_and_taxonomy" } ] }, { "name": "Carnitine/acylcarnitine translocase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 25 member 20", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mediates the electroneutral exchange of acylcarnitines (O-acyl-(R)-carnitine or L-acylcarnitine) of different acyl chain lengths (ranging from O-acetyl-(R)-carnitine to long-chain O-acyl-(R)-carnitines) with free carnitine ((R)-carnitine or L-carnitine) across the mitochondrial inner membrane, via a ping-pong mechanism. Key player in the mitochondrial oxidation pathway, it translocates the fatty acids in the form of acylcarnitines into the mitochondrial matrix, where the carnitine palmitoyltransferase 2 (CPT-2) activates them to undergo fatty acid beta-oxidation. Catalyzes the unidirectional transport (uniport) of carnitine at lower rates than the antiport (exchange).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5#function" }, { "database": "UniProtKB", "id": "ARBA00056740", "url": "https://www.uniprot.org/uniprotkb/ARBA00056740#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC25A20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5", "locus": { "chromosome": "12", "start_pos": 11895787, "end_pos": 11884548, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020754", "url": "https://www.ensembl.org/id/ENSGALG00010020754" } ] } } ], "crossref": [ { "id": "A0A8V0ZFV5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFV5", "database": "AlphaFoldDB", "categories": [] }, { "id": "416062", "url": "https://www.ncbi.nlm.nih.gov/gene/416062", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEI5", "url": "https://www.orthodb.org/?gene=A0A8V0ZEI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFV5", "url": "https://www.orthodb.org/?gene=A0A8V0ZFV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLX6", "url": "https://www.orthodb.org/?gene=A0A8V0ZLX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624:SF56", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624:SF56", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-200425", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-200425", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "34959", "url": "https://www.rhea-db.org/rhea/34959", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "49908", "url": "https://www.rhea-db.org/rhea/49908", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "49912", "url": "https://www.rhea-db.org/rhea/49912", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "49916", "url": "https://www.rhea-db.org/rhea/49916", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "49920", "url": "https://www.rhea-db.org/rhea/49920", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "49924", "url": "https://www.rhea-db.org/rhea/49924", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZEI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEQPQPISPVKNFFAGGFGGVCLVFVGHPLDTIKVRLQTQPRPQPGQPPLYSGTFDCFRKTLTGEGVRGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQKKPDDILTYPQLFAAGMLSGVFTTAIMAPGERIKCLLQIQAATGETKYSGSLDCAKQLYREAGIRGVYKGTVLTLMRDVPASGMYFMTYEWLKNVLTPEGKSVSDLSVPRILFAGGLAGIFNWAVAIPPDVLKSRFQTGKYPNGFRDVLRELIREEGVASLYKGFTAVMIRAFPANAACFLGFEVAMKFLNWIVPGL", "length": 298, "header": "tr|A0A8V0ZFV5-1|A0A8V0ZFV5_CHICK Isoform 1 of Mitochondrial carnitine/acylcarnitine carrier protein OS=Gallus gallus OX=9031 GN=SLC25A20 PE=1 SV=1 CANONICAL=A0A8V0ZFV5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5/entry#A0A8V0ZEI5-1", "sequence": { "sequence": "MAEQPQPISPVKNFFAGGFGGVCLVFVGHPLDTIKVRLQTQPRPQPGQPPLYSGTFDCFRKTLTGEISSAVCSWHVVRSVHNSNHGSRRENQVPFTDVPASGMYFMTYEWLKNVLTPEGKSVSDLSVPRILFAGGLAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVASLYKGFTAVMIRAFPANAACFLGFEVAMKFLNWIVPGL", "length": 219, "header": "tr|A0A8V0ZEI5-1|A0A8V0ZFV5_CHICK Computationally mapped isoform of Mitochondrial carnitine/acylcarnitine carrier protein OS=Gallus gallus OX=9031 GN=SLC25A20 PE=1 SV=1 CANONICAL=A0A8V0ZFV5-1" }, "locus": { "chromosome": "12", "start_pos": 11894694, "end_pos": 11884879, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050177.1", "url": "https://www.ensembl.org/id/ENSGALT00010050177.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029647.1", "url": "https://www.ensembl.org/id/ENSGALP00010029647.1" } ] } }, { "isoform_ac": "A0A8V0ZFV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5/entry#A0A8V0ZFV5-1", "sequence": { "sequence": "MAEQPQPISPVKNFFAGGFGGVCLVFVGHPLDTIKVRLQTQPRPQPGQPPLYSGTFDCFRKTLTGEGVRGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQKKPDDILTYPQLFAAGMLSGVFTTAIMAPGERIKCLLQIQAATGETKYSGSLDCAKQLYREAGIRGVYKGTVLTLMRDVPASGMYFMTYEWLKNVLTPEGKSVSDLSVPRILFAGGLAGIFNWAVAIPPDVLKSRFQTGKYPNGFRDVLRELIREEGVASLYKGFTAVMIRAFPANAACFLGFEVAMKFLNWIVPGL", "length": 298, "header": "tr|A0A8V0ZFV5-1|A0A8V0ZFV5_CHICK Isoform 1 of Mitochondrial carnitine/acylcarnitine carrier protein OS=Gallus gallus OX=9031 GN=SLC25A20 PE=1 SV=1 CANONICAL=A0A8V0ZFV5-1" }, "locus": { "chromosome": "12", "start_pos": 11894694, "end_pos": 11884879, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050178.1", "url": "https://www.ensembl.org/id/ENSGALT00010050178.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029648.1", "url": "https://www.ensembl.org/id/ENSGALP00010029648.1" } ] } }, { "isoform_ac": "A0A8V0ZLX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5/entry#A0A8V0ZLX6-1", "sequence": { "sequence": "MMLTLCKHRKVRLQTQPRPQPGQPPLYSGTFDCFRKTLTGEGVRGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQKKPDDILTYPQLFAAGMLSGVFTTAIMAPGERIKCLLQIQAATGETKYSGSLDCAKQLYREAGIRGVYKGTVLTLMRDVPASGMYFMTYEWLKNVLTPEGKSVSDLSVPRILFAGGLAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVASLYKGFTAVMIRAFPANAACFLGFEVAMKFLNWIVPGL", "length": 276, "header": "tr|A0A8V0ZLX6-1|A0A8V0ZLX6_CHICK Computationally mapped isoform of Solute carrier family 25 member 20 OS=Gallus gallus OX=9031 GN=SLC25A20 PE=1 SV=1 CANONICAL=A0A8V0ZFV5-1" }, "locus": { "chromosome": "12", "start_pos": 11894694, "end_pos": 11885291, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050173.1", "url": "https://www.ensembl.org/id/ENSGALT00010050173.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029646.1", "url": "https://www.ensembl.org/id/ENSGALP00010029646.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-200425", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-200425", "resource": "Reactome", "description": "Carnitine shuttle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5" } ], "pmid": "" }, { "name": "mitochondrial envelope", "id": "GO:0005740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitochondrial transport", "id": "GO:0006839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5" } ], "pmid": "" }, { "name": "carnitine shuttle", "id": "GO:0006853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006853", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5" } ], "pmid": "" }, { "name": "carnitine transmembrane transport", "id": "GO:1902603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902603", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "O-acyl-L-carnitine transmembrane transporter activity", "id": "GO:0015227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "34959", "name": "", "equation": "(R)-carnitine(in) = (R)-carnitine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34959", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34959" } ] }, { "id": "49908", "name": "", "equation": "O-acetyl-(R)-carnitine(in) + (R)-carnitine(out) = O-acetyl-(R)-carnitine(out) + (R)-carnitine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "49908", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/49908" } ] }, { "id": "49912", "name": "", "equation": "O-propanoyl-(R)-carnitine(in) + (R)-carnitine(out) = O-propanoyl-(R)-carnitine(out) + (R)-carnitine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "49912", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/49912" } ] }, { "id": "49916", "name": "", "equation": "O-hexadecanoyl-(R)-carnitine(in) + (R)-carnitine(out) = O-hexadecanoyl-(R)-carnitine(out) + (R)-carnitine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "49916", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/49916" } ] }, { "id": "49920", "name": "", "equation": "O-octanoyl-(R)-carnitine(in) + (R)-carnitine(out) = O-octanoyl-(R)-carnitine(out) + (R)-carnitine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "49920", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/49920" } ] }, { "id": "49924", "name": "", "equation": "an O-acyl-(R)-carnitine(in) + (R)-carnitine(out) = an O-acyl-(R)-carnitine(out) + (R)-carnitine(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "49924", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/49924" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFP1-1", "uniprot_ac": "A0A8V0ZFP1", "uniprot_id": "A0A8V0ZFP1_CHICK", "mass": { "chemical_mass": 146735.0, "monoisotopic_mass": 146735.0 }, "refseq": {}, "gene_names": [ { "name": "TTBK2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTBK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1", "locus": { "chromosome": "5", "start_pos": 25402766, "end_pos": 25484475, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020762", "url": "https://www.ensembl.org/id/ENSGALG00010020762" } ] } } ], "crossref": [ { "id": "cd14129", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14129", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEK8", "url": "https://www.orthodb.org/?gene=A0A8V0ZEK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFP1", "url": "https://www.orthodb.org/?gene=A0A8V0ZFP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLY1", "url": "https://www.orthodb.org/?gene=A0A8V0ZLY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLZ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZLZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZEK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGGEQPDILTVGILVKERWKLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPQEFNIFLDHISNLDYFTKPDYQLLMSVFDNSMKTFGVIESDPFDWEKSGTDGSLTTTTTSTTPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIPVGVSPEKLPGSPGHQRSQEKDVWEEMDANRNKIKLGICKAATEEENSHGPVNGMLNAPSLGSPVRVRSETTQLDRDVPLVRKLRSIHSFELEKRLTLESKPDTDKFLENCLEKRQKDLNAAAETAVAAVPPLPQKSLIPAPVTSRMDHVWHYDEEYLPDASKPVSAGSPEQVDGVVGNGFVAVNLSSSRQEIDSKEWVIIDKERDLQDFRTNEVLGHKTTGSPSDEEPEVLQVLEESPPEEQPRQGGWAGNSVHAKNQTSGVEFLLAMESHPASSEQLTDKLELLTGAAGQLLAATPTSPMEAQAEGALTPLNSSHMLHFSTPRISSPILRTMSPIAYLSIHPDPLKEAGLPRSQSAESHSSSSRSTGRRQLPVIPCGNKFPPVIRISKAQLRQVTIPRPSVASTQSASESFHYGHQLEKRERDAQSMEQTVELLSPRETLPGLVVTEDTTVSGSRPGMVLHISQEVLGREGHVKECASVLSSGQKDLPEKHSGRQEEKELEKLPVETEEELLPVVSEAAVVMPSKEQNSLPGSSKSADEDPLTNTDAAEESKPRPVCLVPNQDELLKSTAPETPEFSPSRRINPYANRQASKIVPVQENGFHSNKEEVRVQDLQCHQVALTTFLHQEDKKEKNAPRNGELFHCISANENSHRSKKDLVKSPFVFRQSRIPVLAQEIDSTSESSSPVSAKEKLLLKKAHQTDLVRLLVEKRQLKSFLGDLSSASDKSLEEKMAAAPVPFSEDDVLSSFSKLTLDSHFSKQMEDSSLSPSSPQSRKSKIPRPVSWVTTEQINGSSSTQFLPRPPPGKPPTRPGVEARLRRYRVLGSSSSDSDLISRLAQILQNGSQRPRSSTQCKSPGSPHSPKTPPKSPVNPRRSPSASPRSSSLPRTASSSPSRAGRTHHDQRSSSPHLGRSKSPPSHSGSSSSRRSCQQEHCYNKPSKNGLKGSGSSLYHSPSAKTPTGKSKSATKLSR", "length": 1330, "header": "tr|A0A8V0ZFP1-1|A0A8V0ZFP1_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TTBK2 PE=3 SV=1 CANONICAL=A0A8V0ZFP1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1/entry#A0A8V0ZEK8-1", "sequence": { "sequence": "MSGGGEQPDILTVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPQEFNIFLDHISNLDYFTKPDYQLLMSVFDNSMKTFGVIESDPFDWEKSGTDGSLTTTTTSTTPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIPVGVSPEKLPGSPGHQRSQEKDVWEEMDANRNKIKLGICKAATEEENSHGPVNGMLNAPSLGSPVRVRSETTQLDRDVPLVRKLRSIHSFELEKRLTLESKPDTDKFLENCLEKRQKDLNAAAETAVAAVPPLPQKSLIPAPVTSRMDHVWHYDEEYLPDASKPVSAGSPEQVDGVVGNGFVAVNLSSSRQEIDSKEWVIIDKERDLQDFRTNEVLGHKTTGSPSDEEPEVLQVLEESPPEEQPRQGGWAGNSVHAKNQTSGVEFLLAMESHPASSEQLTDKLELLTGAAGQLLAATPTSPMEAQAEGALTPVTIPRPSVASTQSASESFHYGHQLEKRERDAQSMEQTVELLSPRETLPGLVVTEDTTVSGSRPGMVLHISQEVLGREGHVKECASVLSSGQKDLPEKHSGRQEEKELEKLPVETEEELLPVVSEAAVVMPSKEQNSLPGSSKSADEDPLTNTDAAEESKPRPVCLVPNQDELLKSTAPETPEFSPSRRINPYANRQASKIVPVQENGFHSNKEEVRVQDLQCHQVALTTFLHQEDKKEKNAPRNGELFHCISANENSHRSKKDLVKSPFVFRQSRIPVLAQEIDSTSESSSPVSAKEKLLLKKAHQTDLVRLLVEKRQLKSFLGDLSSASDKSLEEKMAAAPVPFSEDDVLSSFSKLTLDSHFSKQMEDSSLSPSSPQSRKSKIPRPVSWVTTEQINGSSSTQFLPRPPPGKPPTRPGVEARLRRYRVLGSSSSDSDLISRLAQILQNGSQRPRSSTQFPAVSS", "length": 1135, "header": "tr|A0A8V0ZEK8-1|A0A8V0ZFP1_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TTBK2 PE=3 SV=1 CANONICAL=A0A8V0ZFP1-1" }, "locus": { "chromosome": "5", "start_pos": 25461786, "end_pos": 25403770, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050215.1", "url": "https://www.ensembl.org/id/ENSGALT00010050215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029672.1", "url": "https://www.ensembl.org/id/ENSGALP00010029672.1" } ] } }, { "isoform_ac": "A0A8V0ZFP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1/entry#A0A8V0ZFP1-1", "sequence": { "sequence": "MSGGGEQPDILTVGILVKERWKLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPQEFNIFLDHISNLDYFTKPDYQLLMSVFDNSMKTFGVIESDPFDWEKSGTDGSLTTTTTSTTPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIPVGVSPEKLPGSPGHQRSQEKDVWEEMDANRNKIKLGICKAATEEENSHGPVNGMLNAPSLGSPVRVRSETTQLDRDVPLVRKLRSIHSFELEKRLTLESKPDTDKFLENCLEKRQKDLNAAAETAVAAVPPLPQKSLIPAPVTSRMDHVWHYDEEYLPDASKPVSAGSPEQVDGVVGNGFVAVNLSSSRQEIDSKEWVIIDKERDLQDFRTNEVLGHKTTGSPSDEEPEVLQVLEESPPEEQPRQGGWAGNSVHAKNQTSGVEFLLAMESHPASSEQLTDKLELLTGAAGQLLAATPTSPMEAQAEGALTPLNSSHMLHFSTPRISSPILRTMSPIAYLSIHPDPLKEAGLPRSQSAESHSSSSRSTGRRQLPVIPCGNKFPPVIRISKAQLRQVTIPRPSVASTQSASESFHYGHQLEKRERDAQSMEQTVELLSPRETLPGLVVTEDTTVSGSRPGMVLHISQEVLGREGHVKECASVLSSGQKDLPEKHSGRQEEKELEKLPVETEEELLPVVSEAAVVMPSKEQNSLPGSSKSADEDPLTNTDAAEESKPRPVCLVPNQDELLKSTAPETPEFSPSRRINPYANRQASKIVPVQENGFHSNKEEVRVQDLQCHQVALTTFLHQEDKKEKNAPRNGELFHCISANENSHRSKKDLVKSPFVFRQSRIPVLAQEIDSTSESSSPVSAKEKLLLKKAHQTDLVRLLVEKRQLKSFLGDLSSASDKSLEEKMAAAPVPFSEDDVLSSFSKLTLDSHFSKQMEDSSLSPSSPQSRKSKIPRPVSWVTTEQINGSSSTQFLPRPPPGKPPTRPGVEARLRRYRVLGSSSSDSDLISRLAQILQNGSQRPRSSTQCKSPGSPHSPKTPPKSPVNPRRSPSASPRSSSLPRTASSSPSRAGRTHHDQRSSSPHLGRSKSPPSHSGSSSSRRSCQQEHCYNKPSKNGLKGSGSSLYHSPSAKTPTGKSKSATKLSR", "length": 1330, "header": "tr|A0A8V0ZFP1-1|A0A8V0ZFP1_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TTBK2 PE=3 SV=1 CANONICAL=A0A8V0ZFP1-1" }, "locus": { "chromosome": "5", "start_pos": 25461786, "end_pos": 25405769, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050197.1", "url": "https://www.ensembl.org/id/ENSGALT00010050197.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029659.1", "url": "https://www.ensembl.org/id/ENSGALP00010029659.1" } ] } }, { "isoform_ac": "A0A8V0ZLY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1/entry#A0A8V0ZLY1-1", "sequence": { "sequence": "MNLSKVTIPRPSVASTQSASESFHYGHQLEKRERDAQSMEQTVELLSPRETLPGLVVTEDTTVSGSRPGMVLHISQEVLGREGHVKECASVLSSGQKDLPEKHSGRQEEKELEKLPVETEEELLPVVSEAAVVMPSKEQNSLPGSSKSADEDPLTNTDAAEESKPRPVCLVPNQDELLKSTAPETPEFSPSRRINPYANRQASKIVPVQENGFHSNKEEVRVQDLQCHQVALTTFLHQEDKKEKNAPRNGELFHCISANENSHRSKKDLVKSPFVFRQSRIPVLAQEIDSTSESSSPVSAKEKLLLKKAHQTDLVRLLVEKRQLKSFLGDLSSASDKSLEEKMAAAPVPFSEDDVLSSFSKLTLDSHFSKQMEDSSLSPSSPQSRKSKIPRPVSWVTTEQINGSSSTQFLPRPPPGKPPTRPGVEARLRRYRVLGSSSSDSDLISRLAQILQNGSQRPRSSTQCKSPGSPHSPKTPPKSPVNPRRSPSASPRSSSLPRTASSSPSRAGRTHHDQRSSSPHLGRSKSPPSHSGSSSSRRSCQQEHCYNKPSKNGLKGSGSSLYHSPSAKTPTGKSKSATKLSR", "length": 582, "header": "tr|A0A8V0ZLY1-1|A0A8V0ZLY1_CHICK Computationally mapped isoform of Tau tubulin kinase 2 OS=Gallus gallus OX=9031 GN=TTBK2 PE=4 SV=1 CANONICAL=A0A8V0ZFP1-1" }, "locus": { "chromosome": "5", "start_pos": 25413061, "end_pos": 25405769, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050186.1", "url": "https://www.ensembl.org/id/ENSGALT00010050186.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029651.1", "url": "https://www.ensembl.org/id/ENSGALP00010029651.1" } ] } }, { "isoform_ac": "A0A8V0ZLZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1/entry#A0A8V0ZLZ6-1", "sequence": { "sequence": 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"length": 1240, "header": "tr|A0A8V0ZLZ6-1|A0A8V0ZLZ6_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=TTBK2 PE=3 SV=1 CANONICAL=A0A8V0ZFP1-1" }, "locus": { "chromosome": "5", "start_pos": 25461786, "end_pos": 25404946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050208.1", "url": "https://www.ensembl.org/id/ENSGALT00010050208.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029666.1", "url": "https://www.ensembl.org/id/ENSGALP00010029666.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "cerebellar granular layer development", "id": "GO:0021681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "cerebellar granule cell precursor tangential migration", "id": "GO:0021935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021935", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" }, { "name": "negative regulation of protein localization to microtubule", "id": "GO:1902817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1150, "end_pos": 1152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1201, "end_pos": 1203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ 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"A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A1D5P517-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-5617816", "name": "RAB3IP stimulates nucleotide exchange on RAB8A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1ABB1-1", "A0A8V1AFH3-1", "A0A8V0Z564-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZFP1-1" ], "evidence": [ { "id": "R-GGA-5617816", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5617816" } ] }, { "id": "R-GGA-5626227", "name": "CP110 and CEP97 dissociate from the centriole", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZFP1-1" ], "evidence": [ { "id": "R-GGA-5626227", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5626227" } ] }, { "id": "R-GGA-5626228", "name": "The distal appendage proteins recruit TTBK2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZFP1-1" ], "evidence": [ { "id": "R-GGA-5626228", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5626228" } ] }, { "id": "R-GGA-5626681", "name": "Recruitment of transition zone proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZFP1-1" ], "evidence": [ { "id": "R-GGA-5626681", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5626681" } ] }, { "id": "R-GGA-5638009", "name": "CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XQ14-1", "A0A8V1AFH3-1", "A0A8V0Z564-1", "A0A8V0ZDW9-1", "F1NCX7-1", "A0A8V0YJI7-1", "A0A8V0ZFP1-1" ], "evidence": [ { "id": "R-GGA-5638009", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5638009" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": 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= O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2TY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] } ] }, { "uniprot_ac": "A0A3Q2U4X3", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] } ] }, { "uniprot_ac": "A0A3Q2U592", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] } ] }, { "uniprot_ac": "A0A3Q2U9U9", "gene_name": "OXSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9U9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U9U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U9U9" } ] } ] }, { "uniprot_ac": "A0A3Q2UF44", "gene_name": "NEK8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] } ] }, { "uniprot_ac": "A0A3Q3A664", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] } ] }, { "uniprot_ac": "A0A3Q3AAD7", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJI7", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJI7" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z564", "gene_name": "RAB11A", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z564" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0Z564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z564" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] 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[ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABB1", "gene_name": "", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ABB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V1ABB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABB1" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFH3", "gene_name": "CSNK1D", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFH3" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIU3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "Q5ZIU3", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q5ZKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKN1" } ] } ] }, { "uniprot_ac": "Q5ZLL1", "gene_name": "CSNK1E", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5ZLL1", "database": "UniProtKB", "url": 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"evidence": [ { "id": "Q6XUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6XUX0" } ] } ] }, { "uniprot_ac": "Q7T0B1", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q7T0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T0B1" } ] } ] }, { "uniprot_ac": "Q8AYC9", "gene_name": "CHEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8AYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8AYC9" } ] } ] }, { "uniprot_ac": "Q8QFP8", "gene_name": "LIMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QFP8" } ] } ] }, { "uniprot_ac": "Q8QGX4", "gene_name": "PRKDC", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q8QGX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8QGX4" } ] } ] }, { "uniprot_ac": "Q90771", "gene_name": "CDK6", "activity": [ { "ec_number": "2.7.11.22", 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFA7-1", "uniprot_ac": "A0A8V0ZFA7", "uniprot_id": "A0A8V0ZFA7_CHICK", "mass": { "chemical_mass": 32546.0, "monoisotopic_mass": 32546.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFA7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFA7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFA7", "locus": {} 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFJ6-1", "uniprot_ac": "A0A8V0ZFJ6", "uniprot_id": "A0A8V0ZFJ6_CHICK", "mass": { "chemical_mass": 49180.0, "monoisotopic_mass": 49180.0 }, "refseq": {}, "gene_names": [ { "name": "P4HTM", "type": "recommended", "evidence": [ { "id": 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Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFB8#function" }, { "database": "UniProtKB", "id": "ARBA00056324", "url": "https://www.uniprot.org/uniprotkb/ARBA00056324#function" }, { "database": "UniProtKB", "id": "A0A8V0ZFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "P4HTM", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6", "locus": { "chromosome": "12", "start_pos": 11839473, "end_pos": 11853006, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020684", "url": "https://www.ensembl.org/id/ENSGALG00010020684" } ] } } ], "crossref": [ { "id": "A0A8V0ZFJ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFJ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFB8", "url": "https://www.orthodb.org/?gene=A0A8V0ZFB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFJ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZFJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10869", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10869", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10869:SF246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10869:SF246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "48400", "url": "https://www.rhea-db.org/rhea/48400", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZFB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVFAHLYVLNVLGLLLFVHLSAGDAGSGPPASAAAPPPPPPPPARALPRLEGIKVGHTQRVELGPGRTRAARTLSLKPLLFEIPDFLTEEECKLIIHLAQLKGLQKSQILPTDDYEEAMEMIEISQMDFFNLLDHNQDGQLQLKEVLTHTRLGNGRWMTPENIREMYTAVKADPDGNGVLSLEEFKRLNIRDFHKYIGSQKVKMSDAVRNSQHTWLYQGEGAHQVMRAIRQRVMRLTRLPPEIVEHSEPLQVVRYDQGGHYHAHMDSGPVFPETACSHTKLVANESAPFETSCRYVTVLFYLNNVTGGGETVFPIADNRTYEEMSLIQNDVDLRDTRKNCDKGNLRVKPQQGTAVFWYNYLSDGEGWVGELDDFALHGGCLVTQGTKWIANNWINVDPNRRRQQRFQQEMERYAGSGAGAPGEWTVDKAYSGVHVEL", "length": 437, "header": "tr|A0A8V0ZFJ6-1|A0A8V0ZFJ6_CHICK Isoform 1 of Transmembrane prolyl 4-hydroxylase OS=Gallus gallus OX=9031 GN=P4HTM PE=4 SV=1 CANONICAL=A0A8V0ZFJ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6/entry#A0A8V0ZFB8-1", "sequence": { "sequence": "MMLWAQVASMSSHCCSLPGISVLRSGPCFSTSTLEGSRSKSETVVVVFFLRIRIFTAGMGEIPDFLTEEECKLIIHLAQLKGLQKSQILPTDDYEEAMEMIEISQMDFFNLLDHNQDGQLQLKEVLTHTRLGNGRWMTPENIREMYTAVKADPDGNGVLSLEEFKRLNIRDFHKYIGSQKVKMSDAVRNSQHTWLYQGEGAHQVMRAIRQRVMRLTRLPPEIVEHSEPLQVVRYDQGGHYHAHMDSGPVFPETACSHTKLVANESAPFETSCRYVTVLFYLNNVTGGGETVFPIADNRTYEEMSLIQNDVDLRDTRKNCDKGNLRVKPQQGTAVFWYNYLSDGEGWVGELDDFALHGGCLVTQGTKWIANNWINVDPNRRRQQRFQQEMERYAGSGAGAPGEWTVDKAYSGVHVEL", "length": 416, "header": "tr|A0A8V0ZFB8-1|A0A8V0ZFJ6_CHICK Computationally mapped isoform of Transmembrane prolyl 4-hydroxylase OS=Gallus gallus OX=9031 GN=P4HTM PE=4 SV=1 CANONICAL=A0A8V0ZFJ6-1" }, "locus": { "chromosome": "12", "start_pos": 11849724, "end_pos": 11839605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049964.1", "url": "https://www.ensembl.org/id/ENSGALT00010049964.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029512.1", "url": "https://www.ensembl.org/id/ENSGALP00010029512.1" } ] } }, { "isoform_ac": "A0A8V0ZFJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6/entry#A0A8V0ZFJ6-1", "sequence": { "sequence": "MVFAHLYVLNVLGLLLFVHLSAGDAGSGPPASAAAPPPPPPPPARALPRLEGIKVGHTQRVELGPGRTRAARTLSLKPLLFEIPDFLTEEECKLIIHLAQLKGLQKSQILPTDDYEEAMEMIEISQMDFFNLLDHNQDGQLQLKEVLTHTRLGNGRWMTPENIREMYTAVKADPDGNGVLSLEEFKRLNIRDFHKYIGSQKVKMSDAVRNSQHTWLYQGEGAHQVMRAIRQRVMRLTRLPPEIVEHSEPLQVVRYDQGGHYHAHMDSGPVFPETACSHTKLVANESAPFETSCRYVTVLFYLNNVTGGGETVFPIADNRTYEEMSLIQNDVDLRDTRKNCDKGNLRVKPQQGTAVFWYNYLSDGEGWVGELDDFALHGGCLVTQGTKWIANNWINVDPNRRRQQRFQQEMERYAGSGAGAPGEWTVDKAYSGVHVEL", "length": 437, "header": "tr|A0A8V0ZFJ6-1|A0A8V0ZFJ6_CHICK Isoform 1 of Transmembrane prolyl 4-hydroxylase OS=Gallus gallus OX=9031 GN=P4HTM PE=4 SV=1 CANONICAL=A0A8V0ZFJ6-1" }, "locus": { "chromosome": "12", "start_pos": 11852894, "end_pos": 11839605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049969.1", "url": "https://www.ensembl.org/id/ENSGALT00010049969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029516.1", "url": "https://www.ensembl.org/id/ENSGALP00010029516.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" } ], "pmid": "" }, { "name": "hypoxia-inducible factor-proline dioxygenase activity", "id": "GO:0160082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" } ], "pmid": "" }, { "name": "procollagen-proline 4-dioxygenase activity", "id": "GO:0004656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004656", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of erythrocyte differentiation", "id": "GO:0045646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045646", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "48400", "name": "", "equation": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E1C8C0-1", "A0A8V0XX07-1", "A0A8V0ZFJ6-1" ], "evidence": [ { "id": "48400", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48400" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XX07", "gene_name": "EGLN1", "activity": [ { "ec_number": "1.14.11.29", "activity": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "A0A8V0XX07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX07" } ] }, { "ec_number": "1.14.11.29", "activity": "", "evidence": [ { "id": "A0A8V0XX07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX07" } ] } ] }, { "uniprot_ac": "A0A8V0ZFJ6", "gene_name": "P4HTM", "activity": [ { "ec_number": "1.14.11.29", "activity": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "A0A8V0ZFJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" } ] }, { "ec_number": "1.14.11.29", "activity": "", "evidence": [ { "id": "A0A8V0ZFJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" } ] } ] }, { "uniprot_ac": "E1C8C0", "gene_name": "EGLN3", "activity": [ { "ec_number": "1.14.11.29", "activity": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "E1C8C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8C0" } ] }, { "ec_number": "1.14.11.29", "activity": "", "evidence": [ { "id": "E1C8C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C8C0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZFJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ6" }, { "id": "PS51471", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51471" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fe2OG dioxygenase", "eco_id": "ECO_0000259", "start_pos": 246, "end_pos": 396, "start_aa": "His", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.29", "ec_name": "L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "1.14.11.29", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.29" }, { "id": "1.14.11.29", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.29" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 284, "end_pos": 286 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 318, "end_pos": 320 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFC4-1", "uniprot_ac": "A0A8V0ZFC4", "uniprot_id": "A0A8V0ZFC4_CHICK", "mass": { "chemical_mass": 169477.0, "monoisotopic_mass": 169477.0 }, "refseq": { "ac": "XP_004942196", "name": "DNA excision repair protein ERCC-6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942196" }, "gene_names": [ { "name": "ERCC6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ] }, { "name": "ERCC6", "type": "synonym", "evidence": [ { "id": "XP_004942196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942196" } ] } ], "protein_names": [ { "name": "DNA excision repair protein ERCC-6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4/entry#names_and_taxonomy" } ] }, { "name": "ATP-dependent helicase ERCC6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4/entry#names_and_taxonomy" } ] }, { "name": "Cockayne syndrome protein CSB", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4/entry#names_and_taxonomy" } ] }, { "name": "DNA excision repair protein ERCC-6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004942196", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942196" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004942196.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942196", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942196" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ERCC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4", "locus": { "chromosome": "6", "start_pos": 19497153, "end_pos": 19543071, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021829", "url": "https://www.ensembl.org/id/ENSGALG00010021829" } ] } } ], "crossref": [ { "id": "cd18000", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18000", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21397", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21397", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22254", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22254", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423785", "url": "https://www.ncbi.nlm.nih.gov/gene/423785", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423785", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423785", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNITPCQ", "url": "https://omabrowser.org/oma/group/CNITPCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFC4", "url": "https://www.orthodb.org/?gene=A0A8V0ZFC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMF4", "url": "https://www.orthodb.org/?gene=A0A8V0ZMF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMG4", "url": "https://www.orthodb.org/?gene=A0A8V0ZMG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45629", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45629", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45629:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45629:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25875", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25875", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5250924", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5250924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6781823", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6781823", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6782135", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782135", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6782210", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782210", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-73762", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004942196", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942196", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTENSHLPDSIQEQDPITTLSSICPHNAEQKGTEQENGICNSDLVNHFGVHNSDSKPSTSVAVPVEVPRRGQPLLHINRQQIQSVSHSAQAAELKGLGVDVYDQEVLEQGVIQQVDNAINEANRATKIADAEKEYQSVLDDLRSCTTSLKQIDKIIEQLSPQATNNKDINRKLDSVKRQKYNKEQQLKKIRAKQKRLQAVLGGTEILDKVNEIEFEDDEEPGPSSLGSMLMPVQETEWEELIRTGQMTPFGTKIPQKPERKTRRLMLNEASDFEKYLADQAKLSSERKKLALHKRAKKKAQAKNVQCVAPTSATKEKRGKALSKTDKRLKKHLKKLQKHALQVHSKAGIPKEKKNLETTKLKPGQKDDSGESDYVPDEEHLEPEAVEEEEEQASSHAENDSDYELRNLSGKGKYLVKRDSKDAGNDTDYFPSSEEEEHTVGKRKVKRWRDDGDEDYYKQRLRKWQRERLKDKERSVAEELSDESDTEFEEGFKVPGFLFKKLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRYQGLGPTVIVCPATVMHQWVKEFHTWWPPFRVAILHETGSYTNKKVKLIREIASCHGILITSYSYIRLMQDNIHSYDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLKELWSLFDFVFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDAINPYLLRRMKADVKMSLSLPDKNEQVLFCRLTDEQRQVYQNFIDSKEVYQILNGDMQVFSGLVALRKICNHPDLFSGGPKILKCVPDADLEEADQFGYWKRSGKMIVVESLLKIWHKQGHRVLFFTQSRQMLQILEVFLRDRNYSYLRMDGTTTIASRQPLITRYNEDKSIFIFLLTTRVGGIGVNLTGADRVIIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLSSPDVSQGTETSAIFAGTGSDVQVPKHQLKRKLERPADDDTLKGGLHLKKSSSPKYSKSSSSHLTRHRANSSEAIETSEEAKGNLETFDQNSYAKDNAETATDINSVNKSKQESLERADISLSQSLPGGAGSSENAKVTEEEHEVANENAEGDFSLLCGAAGSQEKQVDKTEDGQLDNNHYKCTSKTKHRVDMLSHDSHKEKSKKKHHKDAKFEGERIPHLVKQKRYKKEDSEEKELDPKKNDDYVLEKLFKKTGVHSVMKHDAIMEASSADYVLVEAEANRVAQDALRALKVSRQRCLGAASGVPTWTGVSGLSGAPSGVKSRFGQKRNPMLLSSHSTCVSPMKKCKDADTMKKENVKKNSSNGHFDGKSETGESSSSILDSSSLLAKMRARNHLILPQRTGNEGDENLHQASAPAPGSTEYDELLVDVRNFIAFQARVDGEASTQEILQEFESKLPAAQSCVFRELLRNLCSFHRNPNGEGVWRLKPEFR", "length": 1496, "header": "tr|A0A8V0ZFC4-1|A0A8V0ZFC4_CHICK Isoform 1 of DNA excision repair protein ERCC-6 OS=Gallus gallus OX=9031 GN=ERCC6 PE=3 SV=1 CANONICAL=A0A8V0ZFC4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4/entry#A0A8V0ZFC4-1", "sequence": { "sequence": "MPTENSHLPDSIQEQDPITTLSSICPHNAEQKGTEQENGICNSDLVNHFGVHNSDSKPSTSVAVPVEVPRRGQPLLHINRQQIQSVSHSAQAAELKGLGVDVYDQEVLEQGVIQQVDNAINEANRATKIADAEKEYQSVLDDLRSCTTSLKQIDKIIEQLSPQATNNKDINRKLDSVKRQKYNKEQQLKKIRAKQKRLQAVLGGTEILDKVNEIEFEDDEEPGPSSLGSMLMPVQETEWEELIRTGQMTPFGTKIPQKPERKTRRLMLNEASDFEKYLADQAKLSSERKKLALHKRAKKKAQAKNVQCVAPTSATKEKRGKALSKTDKRLKKHLKKLQKHALQVHSKAGIPKEKKNLETTKLKPGQKDDSGESDYVPDEEHLEPEAVEEEEEQASSHAENDSDYELRNLSGKGKYLVKRDSKDAGNDTDYFPSSEEEEHTVGKRKVKRWRDDGDEDYYKQRLRKWQRERLKDKERSVAEELSDESDTEFEEGFKVPGFLFKKLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRYQGLGPTVIVCPATVMHQWVKEFHTWWPPFRVAILHETGSYTNKKVKLIREIASCHGILITSYSYIRLMQDNIHSYDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLKELWSLFDFVFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDAINPYLLRRMKADVKMSLSLPDKNEQVLFCRLTDEQRQVYQNFIDSKEVYQILNGDMQVFSGLVALRKICNHPDLFSGGPKILKCVPDADLEEADQFGYWKRSGKMIVVESLLKIWHKQGHRVLFFTQSRQMLQILEVFLRDRNYSYLRMDGTTTIASRQPLITRYNEDKSIFIFLLTTRVGGIGVNLTGADRVIIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLSSPDVSQGTETSAIFAGTGSDVQVPKHQLKRKLERPADDDTLKGGLHLKKSSSPKYSKSSSSHLTRHRANSSEAIETSEEAKGNLETFDQNSYAKDNAETATDINSVNKSKQESLERADISLSQSLPGGAGSSENAKVTEEEHEVANENAEGDFSLLCGAAGSQEKQVDKTEDGQLDNNHYKCTSKTKHRVDMLSHDSHKEKSKKKHHKDAKFEGERIPHLVKQKRYKKEDSEEKELDPKKNDDYVLEKLFKKTGVHSVMKHDAIMEASSADYVLVEAEANRVAQDALRALKVSRQRCLGAASGVPTWTGVSGLSGAPSGVKSRFGQKRNPMLLSSHSTCVSPMKKCKDADTMKKENVKKNSSNGHFDGKSETGESSSSILDSSSLLAKMRARNHLILPQRTGNEGDENLHQASAPAPGSTEYDELLVDVRNFIAFQARVDGEASTQEILQEFESKLPAAQSCVFRELLRNLCSFHRNPNGEGVWRLKPEFR", "length": 1496, "header": "tr|A0A8V0ZFC4-1|A0A8V0ZFC4_CHICK Isoform 1 of DNA excision repair protein ERCC-6 OS=Gallus gallus OX=9031 GN=ERCC6 PE=3 SV=1 CANONICAL=A0A8V0ZFC4-1" }, "locus": { "chromosome": "6", "start_pos": 19541668, "end_pos": 19499195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053115.1", "url": "https://www.ensembl.org/id/ENSGALT00010053115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031996.1", "url": "https://www.ensembl.org/id/ENSGALP00010031996.1" } ] } }, { "isoform_ac": "A0A8V0ZMF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4/entry#A0A8V0ZMF4-1", "sequence": { "sequence": "MPTENSHLPDSIQEQDPITTLSSICPHNAEQKGTEQENGICNSDLVNHFGVHNSDSKPSTSVAVPVEVPRRGQPLLHINRQQIQSVSHSAQAAELKGLGVDVYDQEVLEQGVIQQVDNAINEANRATKIADAEKEYQSVLDDLRSCTTSLKQIDKIIEQLSPQATNNKDINRKLDSVKRQKYNKEQQLKKIRAKQKRLQAVLGGTEILDKVNEIEFEDDEEPGPSSLGSMLMPVQETEWEELIRTGQMTPFGTKIPQKPERKTRRLMLNEASDFEKYLADQAKLSSERKKLALHKRAKKKAQAKNVQCVAPTSATKEKRGKALSKTDKRLKKHLKKLQKHALQVHSKAGIPKEKKNLETTKLKPGQKDDSGESDYVPDEEHLEPEAVEEEEEQASSHAENDSDYELRNLSGKGKYLVKRDSKDAGNDTDYFPSSEEEEHTVGKRKVKRWRDDGDEDYYKQRLRKWQRERLKDKERSVAEELSDESDTEFEEGFKVPGFLFKKLFKYQGLGPTVIVCPATVMHQWVKEFHTWWPPFRVAILHETGSYTNKKVKLIREIASCHGILITSYSYIRLMQDNIHSYDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLKELWSLFDFVFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDAINPYLLRRMKADVKMSLSLPDKNEQVLFCRLTDEQRQVYQNFIDSKEVYQILNGDMQVFSGLVALRKICNHPDLFSGGPKILKCVPDADLEEADQFGYWKRSGKMIVVESLLKIWHKQGHRVLFFTQSRQMLQILEVFLRDRNYSYLRMDGTTTIASRQPLITRYNEDKSIFIFLLTTRVGGIGVNLTGADRVIIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLSSPDVSQGTETSAIFAGTGSDVQVPKHQLKRKLERPADDDTLKGGLHLKKSSSPKYSKSSSSHLTRHRANSSEAIETSEEAKGNLETFDQNSYAKDNAETATDINSVNKSKQESLERADISLSQSLPGGAGSSENAKVTEEEHEVANENAEGDFSLLCGAAGSQEKQVDKTEDGQLDNNHYKCTSKTKHRVDMLSHDSHKEKSKKKHHKDAKFEGERIPHLVKQKRYKKEDSEEKELDPKKNDDYVLEKLFKKTGVHSVMKHDAIMEASSADYVLVEAEANRVAQDALRALKVSRQRCLGAASGVPTWTGVSGLSGAPSGVKSRFGQKRNPMLLSSHSTCVSPMKKCKDADTMKKENVKKNSSNGHFDGKSETGESSSSILDSSSLLAKMRARNHLILPQRTGNEGDENLHQASAPAPGSTEYDELLVDVRNFIAFQARVDGEASTQEILQEFESKLPAAQSCVFRELLRNLCSFHRNPNGEGVWRLKPEFR", "length": 1443, "header": "tr|A0A8V0ZMF4-1|A0A8V0ZMF4_CHICK Computationally mapped isoform of DNA excision repair protein ERCC-6 OS=Gallus gallus OX=9031 GN=ERCC6 PE=3 SV=1 CANONICAL=A0A8V0ZFC4-1" }, "locus": { "chromosome": "6", "start_pos": 19541668, "end_pos": 19499195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053107.1", "url": "https://www.ensembl.org/id/ENSGALT00010053107.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031990.1", "url": "https://www.ensembl.org/id/ENSGALP00010031990.1" } ] } }, { "isoform_ac": "A0A8V0ZMG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4/entry#A0A8V0ZMG4-1", "sequence": { "sequence": "MPTENSHLPDSIQEQDPITTLSSICPHNAEQKGTEQENGICNSDLVNHFGVHNSDSKPSTSVAVPVEVPRRGQPLLHINRQQIQSVSHSAQAAELKGLGVDVYDQEVLEQGVIQQVDNAINEANRATKIADAEKEYQSVLDDLRSCTTSLKQIDKIIEQLSPQATNNKDINRKLDSVKRQKYNKEQQLKKIRAKQKRLQAVLGGTEILDKVNEIEFEDDEEPGPSSLGSMLMPVQETEWEELIRTGQMTPFGTKIPQKPERKTRRLMLNEASDFEKYLADQAKLSSERKKLALHKRAKKKAQAKNVQCVAPTSATKEKRGKALSKTDKRLKKHLKKLQKHALQVHSKAGIPKEKKNLETTKLKPGQKDDSGESDYVPDEEHLEPEAVEEEEEQASSHAENDSDYELRNLSGKGKYLVKRDSKDAGNDTDYFPSSEEEEHTVGKRKVKRWRDDGDEDYYKQRLRKWQRERLKDKERSVAEELSDESDTEFEEGFKVPGFLFKKLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRYQGLGPTVIVCPATVMHQWVKEFHTWWPPFRVAILHETGSYTNKKVKLIREIASCHGILITSYSYIRLMQDNIHSYDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLKELWSLFDFVFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVLFCRLTDEQRQVYQNFIDSKEVYQILNGDMQVFSGLVALRKICNHPDLFSGGPKILKCVPDADLEEADQFGYWKRSGKMIVVESLLKIWHKQGHRVLFFTQSRQMLQILEVFLRDRNYSYLRMDGTTTIASRQPLITRYNEDKSIFIFLLTTRVGGIGVNLTGADRVIIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLSSPDVSQGTETSAIFAGTGSDVQVPKHQLKRKLERPADDDTLKGGLHLKKSSSPKYSKSSSSHLTRHRANSSEAIETSEEAKGNLETFDQNSYAKDNAETATDINSVNKSKQESLERADISLSQSLPGGAGSSENAKVTEEEHEVANENAEGDFSLLCGAAGSQEKQVDKTEDGQLDNNHYKCTSKTKHRVDMLSHDSHKEKSKKKHHKDAKFEGERIPHLVKQKRYKKEDSEEKELDPKKNDDYVLEKLFKKTGVHSVMKHDAIMEASSADYVLVEAEANRVAQDALRALKVSRQRCLGAASGVPTWTGVSGLSGAPSGVKSRFGQKRNPMLLSSHSTCVSPMKKCKDADTMKKENVKKNSSNGHFDGKSETGESSSSILDSSSLLAKMRARNHLILPQRTGNEGDENLHQASAPAPGSTEYDELLVDVRNFIAFQARVDGEASTQEILQEFESKLPAAQSCVFRELLRNLCSFHRNPNGEGVWRLKPEFR", "length": 1457, "header": "tr|A0A8V0ZMG4-1|A0A8V0ZMG4_CHICK Computationally mapped isoform of DNA excision repair protein ERCC-6 OS=Gallus gallus OX=9031 GN=ERCC6 PE=3 SV=1 CANONICAL=A0A8V0ZFC4-1" }, "locus": { "chromosome": "6", "start_pos": 19541668, "end_pos": 19499195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053121.1", "url": "https://www.ensembl.org/id/ENSGALT00010053121.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032000.1", "url": "https://www.ensembl.org/id/ENSGALP00010032000.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 312, "start_aa": "Thr", "end_pos": 312, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr312", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423785", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423785", "resource": "KEGG Pathway" }, { "id": "R-GGA-5250924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5250924", "resource": "Reactome", "description": "B-WICH complex positively regulates rRNA expression" }, { "id": "R-GGA-6781823", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6781823", "resource": "Reactome", "description": "Formation of TC-NER Pre-Incision Complex" }, { "id": "R-GGA-6782135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782135", "resource": "Reactome", "description": "Dual incision in TC-NER" }, { "id": "R-GGA-6782210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782210", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in TC-NER" }, { "id": "R-GGA-73762", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73762", "resource": "Reactome", "description": "RNA Polymerase I Transcription Initiation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTU1-1", "protein_name": "DNA excision repair protein ERCC-6", "gene_name": "Ercc6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHEEIPNSTQPQGQDWLPGQHVSADRDIPAGQETAGDSEAGKCLSSPSCDHGPSTSAEACVLAATRWGPALLHIDRHQIPAVEPSAQALELQGLGVDVYDQAVLEEGVLQQVDSAMHEASRVAQRADAEKEYQSVLDDLMSCTTSLRQINKIIEQLSPQAASNRDINRKLDSVKRQKYNKEQQLKKITAKQKRLQAILGGAEVHVELDHGSLEEEDAEPGPSCLGSMLMPAQESAWEELIRTGQMTPFGTPAPQKQEKKPRKIMLNEASGFEKYLADQAQLSFKRKKQAANKRTAKKAVVVSESSRGPNETKPNQRSQALSQTDKRLKKHIRKLQRRALQFQGKVGLQRGKRPLEPEERPGAEGDTEGEESGSSPTDGEEEEEQEEEGVAVLSSDDISYELKPLRKGQKYEKKVPVQEIDDDFFPSSEEEDEAVEGRGGGRKVSRRPDDGDEDYYKQRLRRWNRLRLQDKEKLKLEDDSEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTLIVCPTTVMHQWVKEFHTWWPPFRVAILHETGSCAHRKERLVRDIVHCHGVLITSYSYIRLMQDDISRHDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFTFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFIDSKAVYRILNGENQIFSGLVALRKICNHPDLFSGGPKNTSALPEDGLEEEQFGYWKRSGKMIVVESLLKIWHKQGQRVLLFSQSRQMLHILEVFLRAHKYSYLKMDGTTTIASRQPLITKYNEDTSIFVFLLTTRVGGLGVNLTGANRVIIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLTSPDASQGTETSAIFAGTGSNIQTLKCHFKKRTPPVLQMDPKRKKPLVSDTSVNGATVMEEKSQGSGATGSVPSTESGPLKSDRHTDGSRASSVGFGEEADAGSTLEHLSGLSGDSPAVDHTSRLSAVASTSEKQGSSYEGECCQAQTGPVHLSEQTEGHFSKHKSKRKHDAAEEETTEKCPQPKQKAKNSRHHRDAKFEGTRVPHLVKKRRYHQQTTEQESGAKDRSSDDYVLEKLFKKSVGVHSVVKHDAIIDGSSPDYVLVEAEANRVAQDALKALRLSRQQCLGATSGVPTWTGHRGISGAPAGVKKRFGQKRNSSLPVQRPSSLTERTQNMKKEGEAHTAEHFSGKEDGASSSGAPSSSSLLARMRARNHMILPERLESDGEQLAGAAAAAAPPCSTEHDALLVDMRNFIAFQAQVDGQASTQEILQAFESKLSVAQSCVFRELLRNLCNFHRTPGGEGIWKLKPEYC", "length": 1474 }, "evidence": [ { "id": "A0A8V0ZFC4", "url": "https://omabrowser.org/oma/group/A0A8V0ZFC4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8C2M3D5-1", "protein_name": "DNA excision repair protein ERCC-6", "gene_name": "Ercc6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPYEEIPNSPQPQDQDCSPSQHVSANEDMPVGQESGGDSETGECISTSFEYGPSTSAEACVLAATRRGPSLLHIDRHQIPAVEPSAQALELQGLGVDVYDQAVLEQGVLQQVDSAMHEASRVAQFADAEKEYQSVLDDLMSCTTSLRQINKIIEQLSPQAATNRDINRKLDSVKRQKCNKEQQLKKITAKQRRLQAILGGAEVQIELDHANLEEEDAEPGPSCLGSMLMPAQEATWEELIRTGQMTPFGTPAPQKQEKKPRKIMLNEVSGFEKYLADQAQLSFERKKRTANKRAAKKAVVVSESCAEPNETKPGQRSQGLSQADKRLKKHIRKLQKRALQFQGKVGLSRGKKPLEPEVRPEAEGDTEGEVSGEEEEEEQEEEKEEEGVANLSSDDVTYELRPLRKGRKYQKKVPVQDVDDDFFPSSGEEDEAMEGRGGGRKVARCPDDGDEAYYKQRLRRWNKLRLQDKEKRLKLEDDSEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTIIVCPTTVMHQWVKEFHMWWPPFRVAILHETGSYAHKKERLVRDIVHCHGVLITSYSYIRLMQDDISRHDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFIDSKEVYRILNGENQIFSGLVALRKICNHPDLFSGGPKNLSGLPEDELEEDQFGYWKRSGKMIVVESLLKIWHKQGQRVLLFSQSRQMLHILEVFLRAHKYSYLKMDGTTTIASRQPLITKYNEDTSIFVFLLTTRVGGIGVNLTGANRVIIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLSSPDASQSTETSAIFAGTGSDVQTPKCHFKKKTPPALGTDPKCKKFPFSDTSANGAILTEEESKATGAAGSATSREGGPLKDDCHPSGSRANSVAFGEETGTGSKLEQVSVISGDGKYSDVPTVDQTSGPSCEASTSEKQGPSYKGECCQVQTEPVCVSEQTDGHFCKHKSKRKHGVTKEETPEKHPQPKQKAKTSKHCRDAKFEGTRVPYLVKKRRYHQQNSEQESKAKERSSDDYVLEKLFKKSVGVHSVVKHDAIMDGTNPDYVLVEAEATRVAQDALKALKFSRQQCLGAASGVPTWTGHRGISGAPAGIKNRFGKKRNSNLPVQRSSSSLTEKHQNNVKKEGKAPAPEHFSGKEDGVSLSGAPSSSSLLARMRARNHLILPERLETDSGHLAEAAALPPCSTEHDDLLVEMRNFIAFQAQVDGQASTQEILQEFESKLSVAQSCVFRELLRNLCNFHRTPGGEGIWKLKPEYC", "length": 1478 }, "evidence": [ { "id": "A0A8V0ZFC4", "url": "https://omabrowser.org/oma/group/A0A8V0ZFC4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F8VPZ5-1", "protein_name": "DNA excision repair protein ERCC-6", "gene_name": "Ercc6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHEEVPNSTHPQEQDCLPSQHANAYKDMPVGQENGGVSEAGECLSSTSCEYGPSTSAEACVLAATRRGPTLLHIDRHQIPAVEPSAQALELQGLGVDVYDQAVLEQGVLQQVDSAMHEASCVAQLADAEKEYQSVLDDLMSCTTSLRQINKIIEQLSPQAASNRDINRKLDSVKRQKYNKEQQLKKITAKQKRLQAILGGAGVQVELDHASLEEDDAEPGPSCLGSMLMPAQETAWEELIRTGQMTPFGTPAPQKQEKKPRKIMLNEASGFEKYLAEQAQLSFERKKQAATKRTAKKAIVISESSRAAIETKADQRSQVLSQTDKRLKKHSRKLQRRALQFQGKVGLPSGKKPLEPEVRPEAEGDTEGEESGSSPTDGEEEEEQEEEEGVASLSSDDVSYELKPLRKRQKYQKKVPVQEIDDDFFPSSEEEDEAMEGRGGGRKVARRQDDGDEDYYKQRLRRWNRLRLQDKEKRLKLEDDSEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTIIVCPTTVMHQWVKEFHTWWPPFRVAVLHETGSYTHKKERLIRDIVYCHGVLITSYSYIRLMQDDISRHDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFIDSKAVYRILNGENQIFSGLVALRKICNHPDLFSGGPKNASGPPEDELEEEQFGHWRRSGKMIVVESLLKIWHRQGQRVLLFSQSRQMLHILEVFLRAHKYSYLKMDGTTTIASRQPLITKYNEDTSIFVFLLTTRVGGLGVNLTGANRVIIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLTSPDASQGTETSAIFAGTGSSIQTPKCQLKKRTSTVLGTDPKCKKPPVSDTPANAATLIGEKPKAAGATGRSVTSGESGPFKGDHDTNGNRASSVAFGEETDAGSTLEHLSVMSGDGKHSDSPTVDHTSRPPVEASTSEKQGSSYAGARCQAQTEPVPMSEQMEGQFSKYKSKRKHDASEEETTEKRPQPKQKAKNSKHCRDAKFEGTRVPHLVKKRRYRQQTSEQEGGAKDRSSDDYVLEKLFKKSVGVHSVVRHDAIIDGSSPDYVLVEAEANRVAQDALKALRLSRQQCLGAASGVPTWTGHRGISGAPTGVKNRFGQKRDSSLPVQHPSSLTEKTQNNMKKEGKAHTPEHFSGKEDGASVSGAPSSSSLLARMRARNHMILPERLESDSEHLAEAAAVPPCGTEHDDLLVDMRNFIAFQAQVDGQASTQEILQEFESKLSVAQSCVFRELLRNLCNFHRTPGGEGIWKLKPEYC", "length": 1481 }, "evidence": [ { "id": "A0A8V0ZFC4", "url": "https://omabrowser.org/oma/group/A0A8V0ZFC4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q03468-1", "protein_name": "DNA excision repair protein ERCC-6", "gene_name": "ERCC6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPNEGIPHSSQTQEQDCLQSQPVSNNEEMAIKQESGGDGEVEEYLSFRSVGDGLSTSAVGCASAAPRRGPALLHIDRHQIQAVEPSAQALELQGLGVDVYDQDVLEQGVLQQVDNAIHEASRASQLVDVEKEYRSVLDDLTSCTTSLRQINKIIEQLSPQAATSRDINRKLDSVKRQKYNKEQQLKKITAKQKHLQAILGGAEVKIELDHASLEEDAEPGPSSLGSMLMPVQETAWEELIRTGQMTPFGTQIPQKQEKKPRKIMLNEASGFEKYLADQAKLSFERKKQGCNKRAARKAPAPVTPPAPVQNKNKPNKKARVLSKKEERLKKHIKKLQKRALQFQGKVGLPKARRPWESDMRPEAEGDSEGEESEYFPTEEEEEEEDDEVEGAEADLSGDGTDYELKPLPKGGKRQKKVPVQEIDDDFFPSSGEEAEAASVGEGGGGGRKVGRYRDDGDEDYYKQRLRRWNKLRLQDKEKRLKLEDDSEESDAEFDEGFKVPGFLFKKLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTVIVCPTTVMHQWVKEFHTWWPPFRVAILHETGSYTHKKEKLIRDVAHCHGILITSYSYIRLMQDDISRYDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFVDSKEVYRILNGEMQIFSGLIALRKICNHPDLFSGGPKNLKGLPDDELEEDQFGYWKRSGKMIVVESLLKIWHKQGQRVLLFSQSRQMLDILEVFLRAQKYTYLKMDGTTTIASRQPLITRYNEDTSIFVFLLTTRVGGLGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVLKDPKQRRFFKSNDLYELFTLTSPDASQSTETSAIFAGTGSDVQTPKCHLKRRIQPAFGADHDVPKRKKFPASNISVNDATSSEEKSEAKGAEVNAVTSNRSDPLKDDPHMSSNVTSNDRLGEETNAVSGPEELSVISGNGECSNSSGTGKTSMPSGDESIDEKLGLSYKRERPSQAQTEAFWENKQMENNFYKHKSKTKHHSVAEEETLEKHLRPKQKPKNSKHCRDAKFEGTRIPHLVKKRRYQKQDSENKSEAKEQSNDDYVLEKLFKKSVGVHSVMKHDAIMDGASPDYVLVEAEANRVAQDALKALRLSRQRCLGAVSGVPTWTGHRGISGAPAGKKSRFGKKRNSNFSVQHPSSTSPTEKCQDGIMKKEGKDNVPEHFSGRAEDADSSSGPLASSSLLAKMRARNHLILPERLESESGHLQEASALLPTTEHDDLLVEMRNFIAFQAHTDGQASTREILQEFESKLSASQSCVFRELLRNLCTFHRTSGGEGIWKLKPEYC", "length": 1493 }, "evidence": [ { "id": "A0A8V0ZFC4", "url": "https://omabrowser.org/oma/group/A0A8V0ZFC4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "double-strand break repair via classical nonhomologous end joining", "id": "GO:0097680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097680", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "base-excision repair", "id": "GO:0006284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "single strand break repair", "id": "GO:0000012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase III", "id": "GO:0045945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045945", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "transcription-coupled nucleotide-excision repair", "id": "GO:0006283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": "GO:0071168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription, elongation", "id": "GO:0032786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "negative regulation of double-strand break repair via nonhomologous end joining", "id": "GO:2001033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001033", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 9, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "protein tyrosine kinase activator activity", "id": "GO:0030296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "ATP-dependent chromatin remodeler activity", "id": "GO:0140658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140658", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "ATP-dependent DNA damage sensor activity", "id": "GO:0140664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1074, "end_pos": 1076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1112, "end_pos": 1114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1365, "end_pos": 1367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 714, "end_pos": 716, "annotation": "n_glycosylation_sequon" }, { "start_pos": 876, "end_pos": 878, "annotation": "n_glycosylation_sequon" }, { "start_pos": 919, "end_pos": 921, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZFC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 515, "end_pos": 691, "start_aa": "Trp", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZFC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC4" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 840, "end_pos": 999, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 312 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1074, "end_pos": 1076 }, { "start_pos": 1112, "end_pos": 1114 }, { "start_pos": 1365, "end_pos": 1367 }, { "start_pos": 400, "end_pos": 402 }, { "start_pos": 408, "end_pos": 410 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 714, "end_pos": 716 }, { "start_pos": 876, "end_pos": 878 }, { "start_pos": 919, "end_pos": 921 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFD5-1", "uniprot_ac": "A0A8V0ZFD5", "uniprot_id": "A0A8V0ZFD5_CHICK", "mass": { "chemical_mass": 80736.0, "monoisotopic_mass": 80736.0 }, "refseq": { "ac": "XP_004944118", "name": "translin-associated factor X-interacting protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944118" }, "gene_names": [ { "name": "TSNAXIP1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFD5" } ] }, { "name": "TSNAXIP1", "type": "synonym", "evidence": [ { "id": "XP_004944118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944118" } ] } ], "protein_names": [ { "name": "Translin associated factor X interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFD5/entry#names_and_taxonomy" } ] }, { "name": "translin-associated factor X-interacting protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004944118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944118" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004944118.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944118", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944118" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFD5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TSNAXIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFD5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZFD5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "769262", "url": "https://www.ncbi.nlm.nih.gov/gene/769262", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769262", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769262", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EWGYNLH", "url": "https://omabrowser.org/oma/group/EWGYNLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFD5", "url": "https://www.orthodb.org/?gene=A0A8V0ZFD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKR9", "url": "https://www.orthodb.org/?gene=A0A8V0ZKR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKS4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16306", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16306", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16306:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16306:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004944118", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944118", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARRAVRGGTSPESSSEITSGQTHIRSAKPTLPKKQKALSLQLSARGQWSMWPAFAAGQTVLRNHKPCSAPEERTCSNEQALLTIPKPRHLEQLESYLRKELQTLDLTKGISQELKLQPYREIFEFFIDNFKTYKPLLSAIKNEYEATLAHQKEMIRALEPLKAMVTTVSEECTQQILALQEKEKVEINTLKQEKHHLLKFIDNMKEEKCSLQTQVEHLQMSVAEEYTRYLQEYGARKLLLAKLNDMHNEQLNVKQHQAQEKAVKGEDVVKLTLALKMARQDLTKAQVKLNAMTAEYGDVVPRRRFESLEKKYSDLLQEMKTLRKDFDQLHEEYGTLLEIHRETAEERDSFFTRLQEAERSHTPRPNWAKCSEVIPGGAERWDCLAKGKSSHQLVDVLLEEIGTGVLKEMNVFRGWGKGNKVPVHLRYEGEVKNKKPTKKDVVNILKDIWKEKTALDQQTGKRSSLPEFFLSYLQKKYGDASAVEWSYTLSEYMRLCPSNHVMSSFYEILTGKVAEEQYHSQNQLISDLQKELAACDSYSSGSLPSEQFRMALREAFPLKRRDAIQELVDASMFSLDSDDDFIDYISLFKEDEEGNPEPFVAKLRSQYVSEKQEYLQELKNSLGDVTEVDADDLKAAFCRIDPEISDQTLDAYIGLAYQVRREQPDQEVVPVDTILERLCVGDVRRVGPSPRKESTTDFEGE", "length": 703, "header": "tr|A0A8V0ZFD5-1|A0A8V0ZFD5_CHICK Isoform 1 of Translin associated factor X interacting protein 1 OS=Gallus gallus OX=9031 GN=TSNAXIP1 PE=4 SV=1 CANONICAL=A0A8V0ZFD5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFD5/entry#A0A8V0ZFD5-1", "sequence": { "sequence": "MAARRAVRGGTSPESSSEITSGQTHIRSAKPTLPKKQKALSLQLSARGQWSMWPAFAAGQTVLRNHKPCSAPEERTCSNEQALLTIPKPRHLEQLESYLRKELQTLDLTKGISQELKLQPYREIFEFFIDNFKTYKPLLSAIKNEYEATLAHQKEMIRALEPLKAMVTTVSEECTQQILALQEKEKVEINTLKQEKHHLLKFIDNMKEEKCSLQTQVEHLQMSVAEEYTRYLQEYGARKLLLAKLNDMHNEQLNVKQHQAQEKAVKGEDVVKLTLALKMARQDLTKAQVKLNAMTAEYGDVVPRRRFESLEKKYSDLLQEMKTLRKDFDQLHEEYGTLLEIHRETAEERDSFFTRLQEAERSHTPRPNWAKCSEVIPGGAERWDCLAKGKSSHQLVDVLLEEIGTGVLKEMNVFRGWGKGNKVPVHLRYEGEVKNKKPTKKDVVNILKDIWKEKTALDQQTGKRSSLPEFFLSYLQKKYGDASAVEWSYTLSEYMRLCPSNHVMSSFYEILTGKVAEEQYHSQNQLISDLQKELAACDSYSSGSLPSEQFRMALREAFPLKRRDAIQELVDASMFSLDSDDDFIDYISLFKEDEEGNPEPFVAKLRSQYVSEKQEYLQELKNSLGDVTEVDADDLKAAFCRIDPEISDQTLDAYIGLAYQVRREQPDQEVVPVDTILERLCVGDVRRVGPSPRKESTTDFEGE", "length": 703, "header": "tr|A0A8V0ZFD5-1|A0A8V0ZFD5_CHICK Isoform 1 of Translin associated factor X interacting protein 1 OS=Gallus gallus OX=9031 GN=TSNAXIP1 PE=4 SV=1 CANONICAL=A0A8V0ZFD5-1" }, "locus": { "chromosome": "11", "start_pos": 890537, "end_pos": 875711, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053129.1", "url": "https://www.ensembl.org/id/ENSGALT00010053129.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032006.1", "url": "https://www.ensembl.org/id/ENSGALP00010032006.1" } ] } }, { "isoform_ac": "A0A8V0ZKR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFD5/entry#A0A8V0ZKR9-1", "sequence": { "sequence": "MWPAFAAGQTVLRNHKPCSAPEERTCSNEQALLTIPKPRHLEQLESYLRKELQTLDLTKGISQELKLQPYREIFEFFIDNFKTYKPLLSAIKNEYEATLAHQKEMIRALEPLKAMVTTVSEECTQQILALQEKEKVEINTLKQEKHHLLKFIDNMKEEKCSLQTQVEHLQMSVAEEYTRYLQEYGARKLLLAKLNDMHNEQLNVKQHQAQEKAVKGEDVVKLTLALKMARQDLTKAQVKLNAMTAEYGDVVPRRRFESLEKKYSDLLQEMKTLRKDFDQLHEEYGTLLEIHRETAEERDSFFTRLQEAERSHTPRPNWAKCSEVIPGGAERWDCLAKGKSSHQLVDVLLEEIGTGVLKEMNVFRGWGKGNKVPVHLRYEGEVKNKKPTKKDVVNILKDIWKEKTALDQQTGKRSSLPEFFLSYLQKKYGDASAVEWSYTLSEYMRLCPSNHVMSSFYEILTGKVAEEQYHSQNQLISDLQKELAACDSYSSGSLPSEQFRMALREAFPLKRRDAIQELVDASMFSLDSDDDFIDYISLFKEDEEGNPEPFVAKLRSQYVSEKQEYLQELKNSLGDVTEVDADDLKAAFCRIDPEISDQTLDAYIGLAYQVRREQPDQEVVPVDTILERLCVGDVRRVGPSPRKESTTDFEGE", "length": 652, "header": "tr|A0A8V0ZKR9-1|A0A8V0ZKR9_CHICK Computationally mapped isoform of Translin associated factor X interacting protein 1 OS=Gallus gallus OX=9031 GN=TSNAXIP1 PE=4 SV=1 CANONICAL=A0A8V0ZFD5-1" }, "locus": { "chromosome": "11", "start_pos": 890537, "end_pos": 877531, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053118.1", "url": "https://www.ensembl.org/id/ENSGALT00010053118.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031998.1", "url": "https://www.ensembl.org/id/ENSGALP00010031998.1" } ] } }, { "isoform_ac": "A0A8V0ZKS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFD5/entry#A0A8V0ZKS4-1", "sequence": { "sequence": "MAARRAVRGGTSPESSSEITSGQTHIRSAKPTLPKKQKALSLQLSARGQWSMWPAFAAGQTVLRNHKPCSAPEERTCSNEQALLTIPKPRHLEQLESYLRKELQTLDLTKGISQELKLQPYREIFEFFIDNFKTYKPLLSAIKNEYEATLEKAVKGEDVVKLTLALKMARQDLTKAQVKLNAMTAEYGDVVPRRRFESLEKKYSDLLQEMKTLRKDFDQLHEEYGTLLEIHRETAEERDSFFTRLQEAERSHTPRPNWAKCSEVIPGGAERWDCLAKGKSSHQLVDVLLEEIGTGVLKEMNVFRGWGKGNKVPVHLRYEGEVKNKKPTKKDVVNILKDIWKEKTALDQQTGKRSSLPEFFLSYLQKKYGDASAVEWSYTLSEYMRLCPSNHVMSSFYEILTGKVAEEQYHSQNQLISDLQKELAACDSYSSGSLPSEQFRMALREAFPLKRRDAIQELVDASMFSLDSDDDFIDYISLFKEDEEGNPEPFVAKLRSQYVSEKQEYLQELKNSLGDVTEVDADDLKAAFCRIDPEISDQTLDAYIGLAYQVRREQPDQEVVPVDTILERLCVGDVRRVGPSPRKESTTDFEGE", "length": 592, "header": "tr|A0A8V0ZKS4-1|A0A8V0ZKS4_CHICK Computationally mapped isoform of Translin associated factor X interacting protein 1 OS=Gallus gallus OX=9031 GN=TSNAXIP1 PE=4 SV=1 CANONICAL=A0A8V0ZFD5-1" }, "locus": { "chromosome": "11", "start_pos": 890537, "end_pos": 875711, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053125.1", "url": "https://www.ensembl.org/id/ENSGALT00010053125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032003.1", "url": "https://www.ensembl.org/id/ENSGALP00010032003.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769262", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769262", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LNB3-1", "protein_name": "Translin-associated factor X-interacting protein 1", "gene_name": "Tsnaxip1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MANPQTRYYSFSKSRTGTQSSGGTAEVKGVEKRKLSQKRRTLPFQLSMGGHLSPWPTYTSGQTILYQRKPCSEDCRNRTNSWQQHPLGTSKPRYLEQLENYLRKELLLLDLGTDSAQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQREKIRALEPLKAKIITMNEDCSERILAMRAEERYEISLLKKEKMNLLKLIDKKNEEKISLQSEVSKLRKSLAEEYLRYLTERDARKILIGDLNELRYQREDMSLAQSPGVWGEDPVKLTLALKMTRQDLTRIQMELNTMKANFGDVVPRRDFEKQEKINLDLQEQLESLKADYEEVRKEHELLLQLHMTTLKERDQFYAELQEIQRTSTPRPDWTKCEGIIAGGSERWLMLAEGKNSDQLVDVLLEEIGSGLLREKDFFPGLGLEESVPAFLRFDGPVENKKPSKKEVVNILEDAWKERLAQEQKESFQDFFTNFLERRFGSNDAIAWAYTIFENIKLFRSIEVMNQFYAVLMGKRKETVYINQRETMSHLMKEMTNIDTQNEGLITMEQFSTILKTTFPLKKEEQIQELIEAAGWSPDINNVEMFNYRTLFTEDEEGQSEPFVQKLWEQYDSEKEAYLQELKEDLGQELTDEVSLSKMRVALMNIDPSLDKQTLCTYLSQAFQLPVAELPLEDEEKQEEIVVKLETALEQLRIADTKRVGLREPEPAS", "length": 705 }, "evidence": [ { "id": "A0A8V0ZFD5", "url": "https://omabrowser.org/oma/group/A0A8V0ZFD5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A5WVR3-1", "protein_name": "Translin-associated factor X-interacting protein 1", "gene_name": "tsnaxip1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVKDLQLPPLLHSRSSSQFESNDDNNRGLQRHIANKMSRAKLIKQTKEKEKSYFSSEPAEVTFQKPRQIRNYGSLAKPRFLEQLECLLKRELEVLDNTQDSKVQELRLQVYQEVFGHLIEEFKTYKPILSAIKKEYDITLAHLRDQIRDLLPLRPKLVLVSEQCDKKILEMRVQEREEVRALKQECRHLQSVIESMRSQQSALQIQVDHLKEDLATQYQLYRDERDARKLLITRISTMQSTQDAEHDDNNEEDESEDPVVVKMALQVCREDLTKAQIELNRLQAEYSDVVPRRDWDNLNHLHEETLMKLETLQTDFNQVKSEYDTLLEVHQKSAPTTQQHGSDSQHIATTPRPNWEQCSDILGGTERCKELFEGQSSQKRLEILMKEINSQNQFFTGLGTSSDVPIYLRYEGKLKNLKLKKADVIKVIKEIWRNKMADNEKNDDPRDLQTFLHSYLVEQYKDKAGEWAYSLMESVQNNLKDDLICLFNDVLTGKVDESIYHGQTQLLSHLLKVLIQSDITQCGSLTVSEFSEALRKAFPLKSDQDIEELLAAAQTELESSGVRISYQTLYTEDTDGQHKEFLSLVKKQATAERLQYISELRAQLEGKGEVDAEQLWVAFKTIDPSLEPENLEWNLSVAFQTKESELQAQALEKEVVLQRLSVAHVKRAGPKG", "length": 673 }, "evidence": [ { "id": "A0A8V0ZFD5", "url": "https://omabrowser.org/oma/group/A0A8V0ZFD5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZU07-1", "protein_name": "Translin-associated factor X interacting protein 1", "gene_name": "Tsnaxip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANPQTRNQSFSKLRTRTQSSGGTPEAESIEKRKLSQKRRTLPLQLSMCGHLSPWPTYTSGQTILHKRKPCSDDSRNRANSWQQQPLSISKPRYLEQLENYLRKELLLLDLSTDSAQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQREKIRSLEPLKAKIVTVNEDCSERVLAMRAEERHEISVLKKEKMNLLKLIDKKNEEKISLQCEVAKLRKSLAEEYLRYLTERDARKILIGDLNELRYQREDMSLAQSPGVWGEDPVKLTLALKMTRQDLTRTQMELNTMKANFGDVVPRRDFEMQEKTNMELQEQLESLRGDYEEVRKEHEMLLQLHMSTLKERDQFYNELQEIQRTSTPRPDWTKCESVIAGGQERWLVLAEGKNSDQLVDVLLEEIGMGLLREKDFFPGLGFGDSIPPFLRFDGPVKNKKPSKKEVVNLLKDAWKERVAEEQKESFPDFFFNFLERRFGVNEAMAWAYTIFENIKLFRSSEIMSQFYAVLMGKTLESVYINQKDTLFHLLKELINADTQNEGSITMEQFSTVLKTTFPLKKEEQIMELMEAAGWGPDSSNTDMLNYRSLFTEDEEGQSEPFVQKLWEQYNSEKEAYLEELKQELNMEPLEEVTLLKMRGTLMNIDPTMDRQTLSAYLSQAYQIPAIDVPLDDEERQGIISVTLETALDRLKMADTKRVGPREPEQAS", "length": 705 }, "evidence": [ { "id": "A0A8V0ZFD5", "url": "https://omabrowser.org/oma/group/A0A8V0ZFD5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S2K6-1", "protein_name": "Translin associated factor X interacting protein 1", "gene_name": "TSNAXIP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASSKPQCPSLATTSRIHLRPLGVTKDDSFITETKNPQKRKLSQKRKTLLSCPFSIGGHLSPWPRYISDQTILHNRKPCSDDYQKRTNSWQQPLGTTKPRYLEQLENYLRKELLLLDLGTDSAQELRLQPFREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQREKIRALEPLKAKLVIVDEDCKERILAMRAEERYEISMLKKEKMNLLKLIDKKNEEKISLQSEVSKLRKNLAEEYLHYLSERDARKILIADLNELRYQREDMSLAQSPGIWGEDPMKLTLALKMARQDLTRTQMELNTMKANFGDVVPRRDFEMQEKVLKDLQEQLDSLRDDYEEVRKEHEMLLQLHMSTLKERDQFYSELQEIQRTSTPRPDWSKCKDVVAGGRDRWQMLAEGKNSDQLVDVLLEEIGEGLLREKDFFSGLGYGESIPTFLRFDGTVENKKPTKKDVVNILKDAWKERMAEEQKERFPDFFFNFLERRFGPGDAMAWAYTIFEYIKLFQSNEVMSQFHAVLMGKRKESVYIKQKERIAQLLKEMTNADSQNEGLLTVEQLSTVLKSAFPFKTDEKIQELMEAVGWHPSSSNADLLNYHILFTEDEEGQSTPFVQKLWEQYMEEKDAYLQELKLELGLELHEDVTLARMREALMNIDPTLDKQTLNSYLSQAFQFPMTELPEEGEEKEAGIVVQLQTALEQLHMSDVRRMGPREQEPAS", "length": 712 }, "evidence": [ { "id": "A0A8V0ZFD5", "url": "https://omabrowser.org/oma/group/A0A8V0ZFD5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2TAA8-1", "protein_name": "Translin-associated factor X-interacting protein 1", "gene_name": "TSNAXIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGHLSPWPTYTSGQTILQNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGSGLLREKDFFPGLGYGEAIPAFLRFDGLVENKKPSKKDVVNLLKDAWKERLAEEQKETFPDFFFNFLEHRFGPSDAMAWAYTIFENIKIFHSNEVMSQFYAVLMGKRSENVYVTQKETVAQLLKEMTNADSQNEGLLTMEQFNTVLKSTFPLKTEEQIQELMEAGGWHPSSSNADLLNYRSLFMEDEEGQSEPFVQKLWEQYMDEKDEYLQQLKQELGIELHEEVTLPKLRGGLMTIDPSLDKQTVNTYMSQAFQLPESEMPEEGDEKEEAVVEILQTALERLQVIDIRRVGPREPEPAS", "length": 658 }, "evidence": [ { "id": "A0A8V0ZFD5", "url": "https://omabrowser.org/oma/group/A0A8V0ZFD5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99P25-1", "protein_name": "Translin-associated factor X-interacting protein 1", "gene_name": "Tsnaxip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANLQERKSFSKPRISIQASGGTPEAKGIEKRKLSQKRRTLPLQLSLGGHLSPWPTYTSGQTVLHNRKPCSDDSRNRANSCQQQSMSISKPKYLEQLENYLRKELLLLDLSTDSAQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQKERIRSLEPLKAKIVTMNEDCSERVLAMRAEERYEISVLKKEKMNLLKLIDKKNEEKISLQSEVAKLRRSLAEEYLRYLTERDARKILIGDLNELRYQQEDMSLAQTPGVWGEDPVKLTLALKMTRQDLTRTQMELNTMKANSGDVVPRRDLEMQEKTNMELQEQLESLKADYEEVQKEHELLLQLHMSTLKERDQFYNELQEIQRTSTPRPDWTKCESIIAGGPERWLVLAEGKNSDQLVDVLLEEIGMGLLREKDFFPGLGFGDAIPPFLRFDGPVKNKKPSKKEVVNLLKDAWKERIAEEQKEPFPDFFFNFLERRFGVNDAMAWAYTIFENIKLFRSSEIMNQFYAVLMGKNLESVYINQKKTLSHLLKELLSVDTQNEGSITMEQFSTILKTTFPLKKEEQIQELMEAVGWGPDSSNTDMLNYRSLFNEDEEGQSEPFVQRLWEQYESDKEAYLEELKQELDLDPLEDVTLLKMRGTLMNIDPTMDKQTLSAYLSQAYQIPAIDVPLEDEEKQGIISIKVETALDRLRMADTKRVGPREPDPAS", "length": 704 }, "evidence": [ { "id": "A0A8V0ZFD5", "url": "https://omabrowser.org/oma/group/A0A8V0ZFD5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZFD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFD5" }, { "id": "PF15739", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15739" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Translin-associated factor X-interacting protein 1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 96, "end_pos": 207, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFE2-1", "uniprot_ac": "A0A8V0ZFE2", "uniprot_id": "A0A8V0ZFE2_CHICK", "mass": { "chemical_mass": 19156.0, "monoisotopic_mass": 19156.0 }, "refseq": { "ac": "XP_015139282", "name": "SAYSvFN domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139282" }, "gene_names": [ { "name": "SAYSD1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFE2" } ] }, { "name": "SAYSD1", "type": "synonym", "evidence": [ { "id": "XP_015139282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139282" } ] } ], "protein_names": [ { "name": "SAYSVFN motif domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFE2/entry#names_and_taxonomy" } ] }, { "name": "SAYSvFN domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_015139282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139282" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139282" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFE2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SAYSD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFE2", "locus": { "chromosome": "3", "start_pos": 28978177, "end_pos": 28977000, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020654", "url": "https://www.ensembl.org/id/ENSGALG00010020654" } ] } } ], "crossref": [ { "id": "A0A8V0ZFE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "421426", "url": "https://www.ncbi.nlm.nih.gov/gene/421426", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421426", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421426", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAFMRRR", "url": "https://omabrowser.org/oma/group/CAFMRRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFE2", "url": "https://www.orthodb.org/?gene=A0A8V0ZFE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13527", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13527", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13527:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13527:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10260", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10260", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015139282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139282", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAVERRLAQFRAARGSAVAVPPRPAEPPGKAAAPEPAESPDGGGQARPGGAPAPLWARPLLLKVLLWAVLLALFAELELGLPYFVLSLLYWMYAGTRGPAERRQGELSAYSVFNPGCTAIAGTLTAEQLERELHYRPAAGRRPVLDYTCNRVPRCFPARRCLDPRQGTRQYQYN", "length": 175, "header": "tr|A0A8V0ZFE2-1|A0A8V0ZFE2_CHICK Isoform 1 of SAYSVFN motif domain containing 1 OS=Gallus gallus OX=9031 GN=SAYSD1 PE=4 SV=1 CANONICAL=A0A8V0ZFE2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFE2/entry#A0A8V0ZFE2-1", "sequence": { "sequence": "MSAVERRLAQFRAARGSAVAVPPRPAEPPGKAAAPEPAESPDGGGQARPGGAPAPLWARPLLLKVLLWAVLLALFAELELGLPYFVLSLLYWMYAGTRGPAERRQGELSAYSVFNPGCTAIAGTLTAEQLERELHYRPAAGRRPVLDYTCNRVPRCFPARRCLDPRQGTRQYQYN", "length": 175, "header": "tr|A0A8V0ZFE2-1|A0A8V0ZFE2_CHICK Isoform 1 of SAYSVFN motif domain containing 1 OS=Gallus gallus OX=9031 GN=SAYSD1 PE=4 SV=1 CANONICAL=A0A8V0ZFE2-1" }, "locus": { "chromosome": "3", "start_pos": 28977757, "end_pos": 28977006, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", 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Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFG3", "url": "https://www.orthodb.org/?gene=A0A8V0ZFG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKV9", "url": "https://www.orthodb.org/?gene=A0A8V0ZKV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23411", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23411", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25466", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25466", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25466:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25466:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZFG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLPAVWGRAWFQLVFPSIMVCRRPFLRGSMILGLILCCCMLAVLAGTVEGLTPVPELRRVDVVLGCSYVWEGGLSRAFGGSEHPATLVLRGLSVTDDGTLGDVTDYEIPQADHSSSPPIIFEASEQLVSIPYAEALLHVDCSGEEVSCELSPYSFQQEGNGLCSASWFLATIRLSSGISIVLLLRGPSCSSQKEGHDVTLHPKLRIPMSKEGTLLTTVEFQSSSNNTSLRTRLGSSITLDCHFALAPSFLLSSLEWRRQHRGSGRSLFRYRVGNAGLTAQPKVHVDVEQLLGNGDASLTLQEATVNDEGTYICLVSTAQHQVQHNIQLLVSEPPRVRVFPTEASLKRDETITLTCNIAGYYPLDISVSWTQKTPEDEVEISPSNTRFSSHRQSQDGTYSINSYLSVNLATAQAPATYTCHVSHVALEAPISISTHLKAPEHTELEGLVGGGHCHCHFRFCPLHCAQEEKSS", "length": 472, "header": "tr|A0A8V0ZFG3-1|A0A8V0ZFG3_CHICK Isoform 1 of TAP binding protein like OS=Gallus gallus OX=9031 GN=TAPBPL PE=1 SV=1 CANONICAL=A0A8V0ZFG3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG3/entry#A0A8V0ZFG3-1", "sequence": { "sequence": "MVLPAVWGRAWFQLVFPSIMVCRRPFLRGSMILGLILCCCMLAVLAGTVEGLTPVPELRRVDVVLGCSYVWEGGLSRAFGGSEHPATLVLRGLSVTDDGTLGDVTDYEIPQADHSSSPPIIFEASEQLVSIPYAEALLHVDCSGEEVSCELSPYSFQQEGNGLCSASWFLATIRLSSGISIVLLLRGPSCSSQKEGHDVTLHPKLRIPMSKEGTLLTTVEFQSSSNNTSLRTRLGSSITLDCHFALAPSFLLSSLEWRRQHRGSGRSLFRYRVGNAGLTAQPKVHVDVEQLLGNGDASLTLQEATVNDEGTYICLVSTAQHQVQHNIQLLVSEPPRVRVFPTEASLKRDETITLTCNIAGYYPLDISVSWTQKTPEDEVEISPSNTRFSSHRQSQDGTYSINSYLSVNLATAQAPATYTCHVSHVALEAPISISTHLKAPEHTELEGLVGGGHCHCHFRFCPLHCAQEEKSS", "length": 472, "header": "tr|A0A8V0ZFG3-1|A0A8V0ZFG3_CHICK Isoform 1 of TAP binding protein like OS=Gallus gallus OX=9031 GN=TAPBPL PE=1 SV=1 CANONICAL=A0A8V0ZFG3-1" }, "locus": { "chromosome": "1", "start_pos": 76835483, "end_pos": 76829239, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053166.1", "url": "https://www.ensembl.org/id/ENSGALT00010053166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032032.1", "url": "https://www.ensembl.org/id/ENSGALP00010032032.1" } ] } }, { "isoform_ac": "A0A8V0ZKV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG3/entry#A0A8V0ZKV9-1", "sequence": { "sequence": "MVCRRPFLRGSMILGLILCCCMLAVLAGTVEGLTPVPELRRVDVVLGCSYVWEGGLSRAFGGSEHPATLVLRGLSVTDDGTLGDVTDYEIPQADHSSSPPIIFEASEQLVSIPYAEALLHVDCSGEEVSCELSPYSFQQEGNGLCSASWFLATIRLSSGISIVLLLRGPSCSSQKEGHDVTLHPKLRIPMSKEGTLLTTVEFQSSSNNTSLRTRLGSSITLDCHFALAPSFLLSSLEWRRQHRGSGRSLFRYRVGNAGLTAQPKVHVDVEQLLGNGDASLTLQEATVNDEGTYICLVSTAQHQVQHNIQLLVSEPPRVRVFPTEASLKRDETITLTCNIAGYYPLDISVSWTQKTPEDERQLSHSTGSSHLHLPCFTCGSGGAHLHQHPSEGTRTHGIGRTGRGGPLPLPFSFLSSSLCSGGKEQLNQSLSNF", "length": 433, "header": "tr|A0A8V0ZKV9-1|A0A8V0ZKV9_CHICK Computationally mapped isoform of TAP binding protein like OS=Gallus gallus OX=9031 GN=TAPBPL PE=1 SV=1 CANONICAL=A0A8V0ZFG3-1" }, "locus": { "chromosome": "1", "start_pos": 76835506, "end_pos": 76829296, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053175.1", "url": "https://www.ensembl.org/id/ENSGALT00010053175.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032039.1", "url": "https://www.ensembl.org/id/ENSGALP00010032039.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "MHC class I protein complex binding", "id": "GO:0023024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG3" } ], "pmid": "" }, { "name": "TAP complex binding", "id": "GO:0062061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062061", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "peptide antigen assembly with MHC class I protein complex", "id": "GO:0002502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG3" } ], "pmid": "" }, { "name": "negative regulation of antigen processing and presentation of peptide antigen via MHC class I", "id": "GO:0002590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002590", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "MHC class I peptide loading complex", "id": "GO:0042824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042824", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZFG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG3" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 324, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 }, { "start_pos": 227, "end_pos": 229 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFG4-1", "uniprot_ac": "A0A8V0ZFG4", "uniprot_id": "A0A8V0ZFG4_CHICK", "mass": { "chemical_mass": 66132.0, "monoisotopic_mass": 66132.0 }, "refseq": { "ac": "XP_015152479", "name": "kelch-like protein 21 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152479" }, "gene_names": [ { "name": "KLHL21", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ] }, { "name": "KLHL21", "type": "synonym", "evidence": [ { "id": "XP_015152479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152479" } ] } ], "protein_names": [ { "name": "Kelch-like protein 21", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 21 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015152479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152479" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015152479.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152479" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4", "locus": { "chromosome": "21", "start_pos": 560422, "end_pos": 549872, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018941", "url": "https://www.ensembl.org/id/ENSGALG00010018941" } ] } } ], "crossref": [ { "id": "A0A8V0ZFG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428175", "url": "https://www.ncbi.nlm.nih.gov/gene/428175", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFG4", "url": "https://www.orthodb.org/?gene=A0A8V0ZFG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF255", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF255", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015152479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152479", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASAGGGGTAAAAAVGEPAHAVSLLRGLSALRAERSLLDVTVVAGGREFGAHRAVLAAASGYFRAMFGGALREARAERVRLHGVEPECLSRLLDFAYTGRVGGLGPDIAERLLRAADLLQFPAVKEACGAWLARQLEPANALDMQDFAEAFACPALAAAAHRFILRHVSELGAQLERLPLPRLLSYLRDDGLCVPKEEAAFQLALRWVHADPAARAPLLPQLLAHVRLPFVRRFYLLAHVEGEPLVARCPPCLRLLQEARDFQAARLDRHDRGPCARMRPRPSTGLAEILVLVGGCDRDCDELVTVDCYNPRTGHWRYLAEFPEHLGGGYSVAALGNDIYVTGGSDGSRLYDCVWRYNSSVNEWTEVSPMLKAREYHSSTVLDGLLYVIASDSTERYDHSVDSWEALQPMLYPMDNCSTTSCRGKLFAIGSLSGKETMVMQCYDPDSDLWSLVNCGHLPPWSFAPKTVTLNGLMYFIRDDSAEVDVYNPVKNEWDKIPAMLQVHVGGSVAVLGGKLYVSGGYDNTFELSDVLEAYDPETRTWSVAGRLPEPIFWHGSVSIFRQFMPETTQEDDSITLDNTINLNRQRPNLHHQNLNELR", "length": 600, "header": "tr|A0A8V0ZFG4-1|A0A8V0ZFG4_CHICK Isoform 1 of Kelch-like protein 21 OS=Gallus gallus OX=9031 GN=KLHL21 PE=4 SV=1 CANONICAL=A0A8V0ZFG4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4/entry#A0A8V0ZFG4-1", "sequence": { "sequence": "MAASAGGGGTAAAAAVGEPAHAVSLLRGLSALRAERSLLDVTVVAGGREFGAHRAVLAAASGYFRAMFGGALREARAERVRLHGVEPECLSRLLDFAYTGRVGGLGPDIAERLLRAADLLQFPAVKEACGAWLARQLEPANALDMQDFAEAFACPALAAAAHRFILRHVSELGAQLERLPLPRLLSYLRDDGLCVPKEEAAFQLALRWVHADPAARAPLLPQLLAHVRLPFVRRFYLLAHVEGEPLVARCPPCLRLLQEARDFQAARLDRHDRGPCARMRPRPSTGLAEILVLVGGCDRDCDELVTVDCYNPRTGHWRYLAEFPEHLGGGYSVAALGNDIYVTGGSDGSRLYDCVWRYNSSVNEWTEVSPMLKAREYHSSTVLDGLLYVIASDSTERYDHSVDSWEALQPMLYPMDNCSTTSCRGKLFAIGSLSGKETMVMQCYDPDSDLWSLVNCGHLPPWSFAPKTVTLNGLMYFIRDDSAEVDVYNPVKNEWDKIPAMLQVHVGGSVAVLGGKLYVSGGYDNTFELSDVLEAYDPETRTWSVAGRLPEPIFWHGSVSIFRQFMPETTQEDDSITLDNTINLNRQRPNLHHQNLNELR", "length": 600, "header": "tr|A0A8V0ZFG4-1|A0A8V0ZFG4_CHICK Isoform 1 of Kelch-like protein 21 OS=Gallus gallus OX=9031 GN=KLHL21 PE=4 SV=1 CANONICAL=A0A8V0ZFG4-1" }, "locus": { "chromosome": "21", "start_pos": 557903, "end_pos": 552273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010045830.1", "url": "https://www.ensembl.org/id/ENSGALT00010045830.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027316.1", "url": "https://www.ensembl.org/id/ENSGALP00010027316.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "chromosome passenger complex localization to spindle midzone", "id": "GO:0035853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035853", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" }, { "name": "polar microtubule", "id": "GO:0005827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005827", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cullin family protein binding", "id": "GO:0097602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097602", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZFG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG4" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 102, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 359, "end_pos": 361 }, { "start_pos": 417, "end_pos": 419 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGU2-1", "uniprot_ac": "A0A8V0ZGU2", "uniprot_id": "A0A8V0ZGU2_CHICK", "mass": { "chemical_mass": 32432.0, "monoisotopic_mass": 32432.0 }, "refseq": { "ac": "XP_015143953", "name": "F-box/LRR-repeat protein 15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143953" }, "gene_names": [ { "name": "FBXL15", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2" } ] }, { "name": "FBXL15", "type": "synonym", "evidence": [ { "id": "XP_015143953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143953" } ] } ], "protein_names": [ { "name": "F-box/LRR-repeat protein 15", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2/entry#names_and_taxonomy" } ] }, { "name": "F-box/LRR-repeat protein 15", "type": "synonym", "evidence": [ { "id": "XP_015143953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143953" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143953" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXL15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2", "locus": { "chromosome": "6", "start_pos": 17748977, "end_pos": 17743640, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021014", "url": "https://www.ensembl.org/id/ENSGALG00010021014" } ] } } ], "crossref": [ { "id": "A0A8V0ZGU2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22126", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22126", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428951", "url": "https://www.ncbi.nlm.nih.gov/gene/428951", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CHRITER", "url": "https://omabrowser.org/oma/group/CHRITER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFG7", "url": "https://www.orthodb.org/?gene=A0A8V0ZFG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGU2", "url": "https://www.orthodb.org/?gene=A0A8V0ZGU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13318:SF179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13318:SF179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015143953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143953", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLTPSRGCLLDLPWEDILVPHVLCHLPLQQLLGLQRVSKAFQALVQLYLANMRCFDSSQIGLAVPRAAFLNLLKDNKVLQQLELQNCSDWLTDRELLPVITRNHHLHHIQLKGCAQLSCHALMVISLNCPNLRRLSLAHCEWVDSLSLRSLADRCKALEAVDLTACRQLKDEAICYLVQKCSRLKSLSLAVNANVGDVAVEETAKCCPELEHLDLTGCLRVKNDSIRVLAEYCPKLRSLKVKHCHNVAESSLSVLRNRGVELDVEPLPQTALVLLQDMAGFAPFINLQI", "length": 290, "header": "tr|A0A8V0ZGU2-1|A0A8V0ZGU2_CHICK Isoform 1 of F-box/LRR-repeat protein 15 OS=Gallus gallus OX=9031 GN=FBXL15 PE=3 SV=1 CANONICAL=A0A8V0ZGU2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2/entry#A0A8V0ZFG7-1", "sequence": { "sequence": "MSLTPSRGCLLDLPWEDILVPHVLCHLPLQQLLGLQRVSKAFQALVQLYLANMRCFDSSQIGLAVPRAAFLNLLKDNKVLQQLELQNCSDWLTDRELLPVITRNHHLHHIQLKGCAQLSCHALMVISLNCPNLRRLSLAHCEWVDSLSLRSLADRCKALEAVDLTACRQLKDEAICYLVQKCSRLKSLSLAVNANVGDVAVEETAKCCPELEHLDLTGCLRVKNDSIRSRTAAAIGRGDQHVTGIPGGRRNWLLLRRTEGEIDPVGEAGPKGAHSSLWGCLTATAHL", "length": 287, "header": "tr|A0A8V0ZFG7-1|A0A8V0ZGU2_CHICK Computationally mapped isoform of F-box/LRR-repeat protein 15 OS=Gallus gallus OX=9031 GN=FBXL15 PE=3 SV=1 CANONICAL=A0A8V0ZGU2-1" }, "locus": { "chromosome": "6", "start_pos": 17746566, "end_pos": 17744650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050813.1", "url": "https://www.ensembl.org/id/ENSGALT00010050813.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030004.1", "url": "https://www.ensembl.org/id/ENSGALP00010030004.1" } ] } }, { "isoform_ac": "A0A8V0ZGU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2/entry#A0A8V0ZGU2-1", "sequence": { "sequence": "MSLTPSRGCLLDLPWEDILVPHVLCHLPLQQLLGLQRVSKAFQALVQLYLANMRCFDSSQIGLAVPRAAFLNLLKDNKVLQQLELQNCSDWLTDRELLPVITRNHHLHHIQLKGCAQLSCHALMVISLNCPNLRRLSLAHCEWVDSLSLRSLADRCKALEAVDLTACRQLKDEAICYLVQKCSRLKSLSLAVNANVGDVAVEETAKCCPELEHLDLTGCLRVKNDSIRVLAEYCPKLRSLKVKHCHNVAESSLSVLRNRGVELDVEPLPQTALVLLQDMAGFAPFINLQI", "length": 290, "header": "tr|A0A8V0ZGU2-1|A0A8V0ZGU2_CHICK Isoform 1 of F-box/LRR-repeat protein 15 OS=Gallus gallus OX=9031 GN=FBXL15 PE=3 SV=1 CANONICAL=A0A8V0ZGU2-1" }, "locus": { "chromosome": "6", "start_pos": 17746391, "end_pos": 17744650, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050809.1", "url": "https://www.ensembl.org/id/ENSGALT00010050809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030000.1", "url": "https://www.ensembl.org/id/ENSGALP00010030000.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4ABB4-1", "protein_name": "F-box/LRR-repeat protein 15", "gene_name": "Fbxl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPPMEQSGGEQEPGAVRLLDLPWEDVLLPHVLNWVPLRQLLRLQRVSRAFRALVQLHLARLRRFDAAQVGPQIPRAALVRLLRDAEGLQELALAPCHEWLLDEDLVPVLARNPQLRSVALAGCGQLSRRALGALAEGCPRLQRISLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDTAVQELARNCPQLEHLDLTGCLRVGSDGVRTLAEYCPALRSLRVRHCHHVAEPSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV", "length": 300 }, "evidence": [ { "id": "A0A8V0ZGU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BNS0-1", "protein_name": "F-box/LRR-repeat protein 15", "gene_name": "FBXL15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPPMDPSGGEQEPGAVRLLDLPWEDVLLPHVLSRVPLRQLLWLQRVSRAFRALVQLHLARLRRFDAAQVGPQIPRAALAWLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALAGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRNLSLAVNANVGDTAVQELARNCPELQHLDLTGCLRVGSDGIRTLAEYCPALRSLRVRHCHHVAEPSLSRLRKRGVDIDVEPPLHQALVLLQDMVGFAPFVNLQV", "length": 300 }, "evidence": [ { "id": "A0A8V0ZGU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q91W61-1", "protein_name": "F-box/LRR-repeat protein 15", "gene_name": "Fbxl15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPPMEQSGGEQEPGAVRLLDLPWEDVLLPHVLNWVPLRQLLRLQRVSRAFRALVQLHLARLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALAGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDTAVQELARNCPQLEHLDLTGCLRVGSDGVRTLAEYCPALRSLRVRHCHHVAEPSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV", "length": 300 }, "evidence": [ { "id": "A0A8V0ZGU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H469-1", "protein_name": "F-box/LRR-repeat protein 15", "gene_name": "FBXL15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPPMEPSGGEQEPGAVRFLDLPWEDVLLPHVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV", "length": 300 }, "evidence": [ { "id": "A0A8V0ZGU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VMY0-1", "protein_name": "Jetlag, isoform A", "gene_name": "jet", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCTLHPEEEAHLMAMASGGQPTRTASPRPLVTASIAAPRSLFDVCWDDVLIPQVAVYLSLKDLFNLRCCSRTAQRFVEAALEKRQELHLSGNNTKNIDVAFRVLARCCQRLEVLHLACCRWLTDELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLKLSKCQWLTTGAVDALTLHQSKLVEFDISYCGAIGERCLIIFFRKLNKLTVLSLANTPSVTDQVLIQIGNYCRELEHINVIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTELSLAPLRQRRLYIDRPQPDVGLNAYNLNDFYPSDFLVY", "length": 319 }, "evidence": [ { "id": "A0A8V0ZGU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZGU2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2" } ], "pmid": "" }, { "name": "positive regulation of BMP signaling pathway", "id": "GO:0030513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU2" }, { "id": "PF00646", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00646" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 47, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFQ4-1", "uniprot_ac": "A0A8V0ZFQ4", "uniprot_id": "A0A8V0ZFQ4_CHICK", "mass": { "chemical_mass": 57739.0, "monoisotopic_mass": 57739.0 }, "refseq": { "ac": "NP_001384427", "name": "secretin receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384427" }, "gene_names": [ { "name": "SCTR", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4" } ] }, { "name": "SCTR", "type": "synonym", "evidence": [ { "id": "NP_001384427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384427" } ] } ], "protein_names": [ { "name": "Secretin receptor", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4/entry#names_and_taxonomy" } ] }, { "name": "secretin receptor", "type": "synonym", "evidence": [ { "id": "NP_001384427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384427" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EU439607.1, SRR13267649.134151.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1, EU439607.1, BM427402.1 and BU243987.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001384427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384427" } ] }, { "annotation": "Chicken secretin receptor and its structurally-related receptors are activated by chicken secretin and secretin-like peptide", "evidence": [ { "database": "RefSeq", "id": "NP_001384427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384427" }, { "database": "PubMed", "id": "21939730", "url": "https://glygen.org/publication/PubMed/21939730" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCTR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4", "locus": { "chromosome": "7", "start_pos": 27985380, "end_pos": 27970875, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020713", "url": "https://www.ensembl.org/id/ENSGALG00010020713" } ] } } ], "crossref": [ { "id": "A0A8V0ZFQ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15275", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15275", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770943", "url": "https://www.ncbi.nlm.nih.gov/gene/770943", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001771", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001771", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047037", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047037", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PRPDVAC", "url": "https://omabrowser.org/oma/group/PRPDVAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFG9", "url": "https://www.orthodb.org/?gene=A0A8V0ZFG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFQ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZFQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLS1", "url": "https://www.orthodb.org/?gene=A0A8V0ZLS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45620", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45620", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45620:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45620:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384427", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAGALQLKRSIGSGWSKLGREKARRERDKVRGAESQAGEHRQPGDLWCVRDAGSGLWLNMWTISVIIFWISAVLIRAVPPVCDLLNVLKKEEENCAEILSLEARNRTPADDLLSSGRCAGMWDNMSCWPSSAVGYTVSAHCPKFFQMLTGKQGFVYRNCTSEGWSDPYPRPDIACGYNVNDTTNEARRSYFMTLKTMYTIGYCTSLVTLTIALVVLASLRRLRCTRNYIHMHLFTSFILRASSNFIKDNVLFSSEDTNYCDAYTAGCKLTMVFFQYCIMSNYSWLLVEGLYLHSLLVISFFSERKFLWWFIALGWGAPTVFVAAWATARQLSENVGCWDVNTNANTWWIIRGPVVASIFVNFILFVDILRILMRKLSSPEGRSSDFNQYKRLAKSTLLLIPLFGVHYIIFAFFPEDASSGTMEIQLFFELALGSFQGFVVAILYCFLNGEVQLEVQRKWRQWHLSKHLRQQLSTSASNGGSGVTQEMQVTKASPPQDRKATPQRSSIL", "length": 509, "header": "tr|A0A8V0ZFQ4-1|A0A8V0ZFQ4_CHICK Isoform 1 of Secretin receptor OS=Gallus gallus OX=9031 GN=SCTR PE=3 SV=1 CANONICAL=A0A8V0ZFQ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4/entry#A0A8V0ZFG9-1", "sequence": { "sequence": "DWRIAVLYVNFGPAIRAVPPVCDLLNVLKKEEENCAEILSLEARNRTPADDLLSSGRCAGMWDNMSCWPSSAVGYTVSAHCPKFFQMLTGKQGFVYRNCTSEGWSDPYPRPDIACGYNVNDTTNEARRSYFMTLKTMYTIGYCTSLVTLTIALVVLASLRRLRCTRNYIHMHLFTSFILRASSNFIKDNVLFSSEDTNYCDAYTAGCKLTMVFFQYCIMSNYSWLLVEGLYLHSLLVISFFSERKFLWWFIALGWGAPTVFVAAWATARQLSENVGCWDVNTNANTWWIIRGPVVASIFVNFILFVDILRILMRKLSSPEGRSSDFNQYKRLAKSTLLLIPLFGVHYIIFAFFPEDASSGTMEIQLFFELALGSFQGFVVAILYCFLNGEVQLEVQRKWRQWHLSKHLRQQLSTSASNGGSGVTQEMQVTKASPPQDRKATPQRSSIL", "length": 448, "header": "tr|A0A8V0ZFG9-1|A0A8V0ZFQ4_CHICK Computationally mapped isoform of Secretin receptor OS=Gallus gallus OX=9031 GN=SCTR PE=3 SV=1 CANONICAL=A0A8V0ZFQ4-1" }, "locus": { "chromosome": "7", "start_pos": 27984756, "end_pos": 27972919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050061.1", "url": "https://www.ensembl.org/id/ENSGALT00010050061.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029579.1", "url": "https://www.ensembl.org/id/ENSGALP00010029579.1" } ] } }, { "isoform_ac": "A0A8V0ZFQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4/entry#A0A8V0ZFQ4-1", "sequence": { "sequence": "MLAGALQLKRSIGSGWSKLGREKARRERDKVRGAESQAGEHRQPGDLWCVRDAGSGLWLNMWTISVIIFWISAVLIRAVPPVCDLLNVLKKEEENCAEILSLEARNRTPADDLLSSGRCAGMWDNMSCWPSSAVGYTVSAHCPKFFQMLTGKQGFVYRNCTSEGWSDPYPRPDIACGYNVNDTTNEARRSYFMTLKTMYTIGYCTSLVTLTIALVVLASLRRLRCTRNYIHMHLFTSFILRASSNFIKDNVLFSSEDTNYCDAYTAGCKLTMVFFQYCIMSNYSWLLVEGLYLHSLLVISFFSERKFLWWFIALGWGAPTVFVAAWATARQLSENVGCWDVNTNANTWWIIRGPVVASIFVNFILFVDILRILMRKLSSPEGRSSDFNQYKRLAKSTLLLIPLFGVHYIIFAFFPEDASSGTMEIQLFFELALGSFQGFVVAILYCFLNGEVQLEVQRKWRQWHLSKHLRQQLSTSASNGGSGVTQEMQVTKASPPQDRKATPQRSSIL", "length": 509, "header": "tr|A0A8V0ZFQ4-1|A0A8V0ZFQ4_CHICK Isoform 1 of Secretin receptor OS=Gallus gallus OX=9031 GN=SCTR PE=3 SV=1 CANONICAL=A0A8V0ZFQ4-1" }, "locus": { "chromosome": "7", "start_pos": 27984756, "end_pos": 27970949, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050066.1", "url": "https://www.ensembl.org/id/ENSGALT00010050066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029583.1", "url": "https://www.ensembl.org/id/ENSGALP00010029583.1" } ] } }, { "isoform_ac": "A0A8V0ZLS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4/entry#A0A8V0ZLS1-1", "sequence": { "sequence": "MVGPFSACEIARCLGQDCLLPQLVQDMNVGTFKPVLLNHVQLGGSSLTRRGKLDAQIGFVYRNCTSEGWSDPYPRPDIACGYNVNDTTNEARRSYFMTLKTMYTIGYCTSLVTLTIALVVLASLRRLRCTRNYIHMHLFTSFILRASSNFIKDNVLFSSEDTNYCDAYTAGCKLTMVFFQYCIMSNYSWLLVEGLYLHSLLVISFFSERKFLWWFIALGWGAPTVFVAAWATARQLSENVGCWDVNTNANTWWIIRGPVVASIFVNFILFVDILRILMRKLSSPEGRSSDFNQYKRLAKSTLLLIPLFGVHYIIFAFFPEDASSGTMEIQLFFELALGSFQGFVVAILYCFLNGEVQLEVQRKWRQWHLSKHLRQQLSTSASNGGSGVTQEMQVTKASPPQDRKATPQRSSIL", "length": 413, "header": "tr|A0A8V0ZLS1-1|A0A8V0ZLS1_CHICK Computationally mapped isoform of Secretin receptor OS=Gallus gallus OX=9031 GN=SCTR PE=3 SV=1 CANONICAL=A0A8V0ZFQ4-1" }, "locus": { "chromosome": "7", "start_pos": 27984756, "end_pos": 27977730, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050055.1", "url": "https://www.ensembl.org/id/ENSGALT00010050055.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029576.1", "url": "https://www.ensembl.org/id/ENSGALP00010029576.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Characterization of chicken secretin (SCT) and secretin receptor (SCTR) genes: a novel secretin-like peptide (SCT-LP) and secretin encoded in a single gene.", "journal": "Molecular and cellular endocrinology", "date": "2012-01-02", "authors": "Wang Yajun, Huang Guian, Li Juan, Meng Fengyan, He Xiaping, Leung Frederick C", "evidence": [ { "database": "RefSeq", "id": "NP_001384427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384427" } ], "reference": [ { "type": "PubMed", "id": "21939730", "url": "https://glygen.org/publication/PubMed/21939730" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P23811-1", "protein_name": "Secretin receptor", "gene_name": "Sctr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSTMRPRLSLLLLRLLLLTKAAHTVGVPPRLCDVRRVLLEERAHCLQQLSKEKKGALGPETASGCEGLWDNMSCWPSSAPARTVEVQCPKFLLMLSNKNGSLFRNCTQDGWSETFPRPDLACGVNINNSFNERRHAYLLKLKVMYTVGYSSSLAMLLVALSILCSFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHKVGCKLVMIFFQYCIMANYAWLLVEGLYLHTLLAISFFSERKYLQAFVLLGWGSPAIFVALWAITRHFLENTGCWDINANASVWWVIRGPVILSILINFIFFINILRILMRKLRTQETRGSETNHYKRLAKSTLLLIPLFGIHYIVFAFSPEDAMEVQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWRQWHLQEFPLRPVAFNNSFSNATNGPTHSTKASTEQSRSIPRASII", "length": 449 }, "evidence": [ { "id": "A0A8V0ZFQ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZFQ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P47872-1", "protein_name": "Secretin receptor", "gene_name": "SCTR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREFPLHPVASFSNSTKASHLEQSQGTCRTSII", "length": 440 }, "evidence": [ { "id": "A0A8V0ZFQ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZFQ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5FWI2-1", "protein_name": "Secretin receptor", "gene_name": "Sctr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMSPRLSLLLLWLLLLINAAHPVGALPRLCDVRRVLLEERAECLRELSEEKKALGPKTASGCERFWDNMSCWPSSALAQTVEVPCPKFLRMFSGRNGSLFRNCTKDGWSETFPRPDLACGVNMNGSFNERRHAYLLKLKVMYTVGYSSSLAMLLVALSILCSFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFPADDVTYCDAHRAGCKLVMIFFQYCIMANYAWLLVEGLYLHTLLAISFFSERKCLQAFVLFGWGSPAIFVALWAVTRHFLEDFGCWDINSNASIWWVIRGPVILSIVINFIFFINILRILMRKLRTQETRGNETHHYKRLAKSTLLLIPLFGIHYIVFAFSPEGAMEVQLFFELALGSFQGLVVAVLYCFLNGELEVQKKWRQWHLQEFPLRPVALSNSFSNATNGPTHSTKAGTSEQSRSIPGANVI", "length": 447 }, "evidence": [ { "id": "A0A8V0ZFQ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZFQ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4" } ], "pmid": "" }, { "name": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "secretin receptor activity", "id": "GO:0015055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4" } ], "pmid": "" }, { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4" } ], "pmid": "" }, { "name": "G protein-coupled peptide receptor activity", "id": "GO:0008528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008528", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4" } ], "pmid": "" }, { "name": "vasoactive intestinal polypeptide receptor activity", "id": "GO:0004999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004999", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZFQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4" }, { "id": "PS50227", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 1", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 180, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZFQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ4" }, { "id": "PS50261", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 2", "eco_id": "ECO_0000259", "start_pos": 195, "end_pos": 449, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 125, "end_pos": 127 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 282, "end_pos": 284 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFH3-1", "uniprot_ac": "A0A8V0ZFH3", "uniprot_id": "A0A8V0ZFH3_CHICK", "mass": { "chemical_mass": 38443.0, "monoisotopic_mass": 38443.0 }, "refseq": {}, "gene_names": [ { "name": "TSPAN15L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3" } ] } ], "protein_names": [ { "name": "Tetraspanin-15", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3#function" }, { "database": "UniProtKB", "id": "ARBA00056423", "url": "https://www.uniprot.org/uniprotkb/ARBA00056423#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TSPAN15L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZFH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03158", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03158", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426128", "url": "https://www.ncbi.nlm.nih.gov/gene/426128", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFH3", "url": "https://www.orthodb.org/?gene=A0A8V0ZFH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLS6", "url": "https://www.orthodb.org/?gene=A0A8V0ZLS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282:SF199", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282:SF199", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZFH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQGSECRNSLLYYYSVKFALSTYATLFSIIGLVILCIGIYAEVERQKHKTLEGMFLAPAIILLLLGFTMFSVSFVGMVGSLRDNRTLLKIFFWVLLVIFITELLLIFIEIIFENKMNAVLHSNIQEGIRHYYDDLDFKNILDFVQEKFSCCGGDEYRDWEVNLYHSCNGSGPLACGVPYTCCIRKVPGEVINTLCGYRTLDKERLELLDVIHVRGCIHAVGLWLKDNFESTLSIVCSLLLPQVVGLVMAWLYWQKLNEIYSQLDTVDFRMLEVRDFSFGALDLSGAGWCWCLPKEGGYIPVNAMEEDEEEGVCATAKRAVSSRGSLGSRTHQHPLHPH", "length": 339, "header": "tr|A0A8V0ZFH3-1|A0A8V0ZFH3_CHICK Isoform 1 of Tetraspanin-15 OS=Gallus gallus OX=9031 GN=TSPAN15L PE=3 SV=1 CANONICAL=A0A8V0ZFH3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3/entry#A0A8V0ZFH3-1", "sequence": { "sequence": "MAQGSECRNSLLYYYSVKFALSTYATLFSIIGLVILCIGIYAEVERQKHKTLEGMFLAPAIILLLLGFTMFSVSFVGMVGSLRDNRTLLKIFFWVLLVIFITELLLIFIEIIFENKMNAVLHSNIQEGIRHYYDDLDFKNILDFVQEKFSCCGGDEYRDWEVNLYHSCNGSGPLACGVPYTCCIRKVPGEVINTLCGYRTLDKERLELLDVIHVRGCIHAVGLWLKDNFESTLSIVCSLLLPQVVGLVMAWLYWQKLNEIYSQLDTVDFRMLEVRDFSFGALDLSGAGWCWCLPKEGGYIPVNAMEEDEEEGVCATAKRAVSSRGSLGSRTHQHPLHPH", "length": 339, "header": "tr|A0A8V0ZFH3-1|A0A8V0ZFH3_CHICK Isoform 1 of Tetraspanin-15 OS=Gallus gallus OX=9031 GN=TSPAN15L PE=3 SV=1 CANONICAL=A0A8V0ZFH3-1" }, "locus": { "chromosome": "22", "start_pos": 3211038, "end_pos": 3174161, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050067.1", "url": "https://www.ensembl.org/id/ENSGALT00010050067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029584.1", "url": "https://www.ensembl.org/id/ENSGALP00010029584.1" } ] } }, { "isoform_ac": "A0A8V0ZLS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3/entry#A0A8V0ZLS6-1", "sequence": { "sequence": "MAQGSECRNSLLYYYSVKFALSTYATLFSIIGLVILCIGIYAEVERQKHKTLEGMFLAPAIILLLLGFTMFSVSFVGMVGSLRDNRTLLKIMNAVLHSNIQEGIRHYYDDLDFKNILDFVQEKFSCCGGDEYRDWEVNLYHSCNGSGPLACGVPYTCCIRKVPGEVINTLCGYRTLDKERLELLDVIHVRGCIHAVGLWLKDNFESTLSIVCSLLLPQVVGLVMAWLYWQKLNEIYSQLDTVDFRMLEVRDFSFGALDLSGAGWCWCLPKEGGYIPVNAMEEDEEEGVCATAKSEEPEG", "length": 299, "header": "tr|A0A8V0ZLS6-1|A0A8V0ZLS6_CHICK Computationally mapped isoform of Tetraspanin-15 OS=Gallus gallus OX=9031 GN=TSPAN15L PE=3 SV=1 CANONICAL=A0A8V0ZFH3-1" }, "locus": { "chromosome": "22", "start_pos": 3211038, "end_pos": 3177054, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050062.1", "url": "https://www.ensembl.org/id/ENSGALT00010050062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029581.1", "url": "https://www.ensembl.org/id/ENSGALP00010029581.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFH5-1", "uniprot_ac": "A0A8V0ZFH5", "uniprot_id": "A0A8V0ZFH5_CHICK", "mass": { "chemical_mass": 36670.0, "monoisotopic_mass": 36670.0 }, "refseq": { "ac": "XP_004947539", "name": "E3 ubiquitin-protein ligase RNF186", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947539" }, "gene_names": [ { "name": "RNF186", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH5" } ] }, { "name": "RNF186", "type": "synonym", "evidence": [ { "id": "XP_004947539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947539" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF186", "type": "synonym", "evidence": [ { "id": "XP_004947539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947539" } ] }, { "name": "Ring finger protein 186", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004947539.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947539", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947539" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF186", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH5", "locus": { "chromosome": "21", "start_pos": 4816068, "end_pos": 4821148, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020672", "url": "https://www.ensembl.org/id/ENSGALG00010020672" } ] } } ], "crossref": [ { "id": "A0A8V0ZFH5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFH5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16557", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16557", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101751836", "url": "https://www.ncbi.nlm.nih.gov/gene/101751836", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101751836", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751836", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHTTGIK", "url": "https://omabrowser.org/oma/group/MHTTGIK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFH5", "url": "https://www.orthodb.org/?gene=A0A8V0ZFH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22791", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22791", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22791:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22791:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004947539", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947539", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHTTGIKEHIKGDRNLGNPSAKGRQTALRFISMEKSTDKLSSENEWTASGVPQAEKVSPAPTAGAAGMSGAGPHAEIAPDVERLAFTEGHSKELESSPGTELDSPDALKAAFSEGDGLNAASLAMVTNPSSPEVRSSERNDQTSPTSSLADMDCLVCFNKYNIYRVPKLLGCQHAFCAVCLKLILRKEENTWVISCPLCRKNTFVSGGLIRTLPNKEEIMDLLEHPDSCPEVHVSGIGLDSSSWAQSSQDVLNRDQTIPADNRLAVQRLVLLLLLLVILTILILPFIYSGMIKWVICIMLTLGLVMSMVLCCTPKFYWSCNGSSLRSCHKETHIAAIA", "length": 338, "header": "tr|A0A8V0ZFH5-1|A0A8V0ZFH5_CHICK Isoform 1 of Ring finger protein 186 OS=Gallus gallus OX=9031 GN=RNF186 PE=4 SV=1 CANONICAL=A0A8V0ZFH5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH5/entry#A0A8V0ZFH5-1", "sequence": { "sequence": "MHTTGIKEHIKGDRNLGNPSAKGRQTALRFISMEKSTDKLSSENEWTASGVPQAEKVSPAPTAGAAGMSGAGPHAEIAPDVERLAFTEGHSKELESSPGTELDSPDALKAAFSEGDGLNAASLAMVTNPSSPEVRSSERNDQTSPTSSLADMDCLVCFNKYNIYRVPKLLGCQHAFCAVCLKLILRKEENTWVISCPLCRKNTFVSGGLIRTLPNKEEIMDLLEHPDSCPEVHVSGIGLDSSSWAQSSQDVLNRDQTIPADNRLAVQRLVLLLLLLVILTILILPFIYSGMIKWVICIMLTLGLVMSMVLCCTPKFYWSCNGSSLRSCHKETHIAAIA", "length": 338, "header": "tr|A0A8V0ZFH5-1|A0A8V0ZFH5_CHICK Isoform 1 of Ring finger protein 186 OS=Gallus gallus OX=9031 GN=RNF186 PE=4 SV=1 CANONICAL=A0A8V0ZFH5-1" }, "locus": { "chromosome": "21", "start_pos": 4816215, "end_pos": 4816068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049935.1", "url": "https://www.ensembl.org/id/ENSGALT00010049935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029490.1", "url": "https://www.ensembl.org/id/ENSGALP00010029490.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZFH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZFH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH5" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 200, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 62 ], "snv_sites": [], "glycation_sites": [], 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Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004940775.1. 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"name": "positive regulation of cell cycle G1/S phase transition", "id": "GO:1902808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902808", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "epithelial cell-cell adhesion", "id": "GO:0090136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "positive regulation of protein localization", "id": "GO:1903829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "negative regulation of mRNA catabolic process", "id": "GO:1902373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902373", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "alpha-catenin binding", "id": "GO:0045294", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045294", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "cornified envelope", "id": "GO:0001533", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001533", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFL9-1", "uniprot_ac": "A0A8V0ZFL9", "uniprot_id": "A0A8V0ZFL9_CHICK", "mass": { "chemical_mass": 34764.0, "monoisotopic_mass": 34764.0 }, "refseq": { "ac": "XP_015148493", "name": "crescent isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148493" }, "gene_names": [ { "name": "LOC395991", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9" } ] }, { "name": "LOC395991", "type": "synonym", "evidence": [ { "id": "XP_015148493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148493" } ] } ], "protein_names": [ { "name": "Secreted frizzled-related protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9/entry#names_and_taxonomy" } ] }, { "name": "crescent isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015148493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148493" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148493.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148493" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC395991", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZFL9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFL9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03580", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03580", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07453", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07453", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395991", "url": "https://www.ncbi.nlm.nih.gov/gene/395991", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WGSPGAW", "url": "https://omabrowser.org/oma/group/WGSPGAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFL9", "url": "https://www.orthodb.org/?gene=A0A8V0ZFL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11309:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11309:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01392", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01392", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148493", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAASTEKASRRRGAPWLPGLLLRLLLWGCAGGRASYLRRSSSCTAIPRSMALCYDIGYSEMRIPNLLEHETMPEVIQQSSSWLPLLARECHPDARIFLCSLFAPICLDRLIYPCRSLCEAVKRSCAPVMACYGYPWPEILNCNKFPADHELCIAAVSTDESSSSRRTVPRASCKDCELEEASTAREILDNLCANDFTVKIRILRKNTTTTVSDFDLDPSRVEVLKHGPLLRTEIPGRLQQWLDIDATCAHNIMRGTHAGVFVISGEVQSDKVVVNKAYAWQKKNRNLHQAVRRWKHHRCPEQAGRKV", "length": 308, "header": "tr|A0A8V0ZFL9-1|A0A8V0ZFL9_CHICK Isoform 1 of Secreted frizzled-related protein 1 OS=Gallus gallus OX=9031 GN=LOC395991 PE=3 SV=1 CANONICAL=A0A8V0ZFL9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9/entry#A0A8V0ZFL9-1", "sequence": { "sequence": "MRAASTEKASRRRGAPWLPGLLLRLLLWGCAGGRASYLRRSSSCTAIPRSMALCYDIGYSEMRIPNLLEHETMPEVIQQSSSWLPLLARECHPDARIFLCSLFAPICLDRLIYPCRSLCEAVKRSCAPVMACYGYPWPEILNCNKFPADHELCIAAVSTDESSSSRRTVPRASCKDCELEEASTAREILDNLCANDFTVKIRILRKNTTTTVSDFDLDPSRVEVLKHGPLLRTEIPGRLQQWLDIDATCAHNIMRGTHAGVFVISGEVQSDKVVVNKAYAWQKKNRNLHQAVRRWKHHRCPEQAGRKV", "length": 308, "header": "tr|A0A8V0ZFL9-1|A0A8V0ZFL9_CHICK Isoform 1 of Secreted frizzled-related protein 1 OS=Gallus gallus OX=9031 GN=LOC395991 PE=3 SV=1 CANONICAL=A0A8V0ZFL9-1" }, "locus": { "chromosome": "12", "start_pos": 11849887, "end_pos": 11847671, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050008.1", "url": "https://www.ensembl.org/id/ENSGALT00010050008.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029541.1", "url": "https://www.ensembl.org/id/ENSGALP00010029541.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8RK92-1", "protein_name": "Secreted frizzled-related protein 1", "gene_name": "LOC101884738", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMLAAFALLLLLLGIGAMPNGHWEHQGTSRCVPIPANMALCQGLGYSSMRMPNLLGHESPAEAVQQSTSWLPLLARECHPHARIFLCSLFAPVCLERIISPCRSLCVSVRDSCAPIMNCYGYPWPRILQCDQFPKDHLMCISSVANLQNGTSNEGRVVPRASCTDCELEEATSSKELLDLFCKSDFVVKVRLSKLNSSSSVLTMFFLGSRLEVLKHGPLLGGEMRSRLTLWLERDATCVGNLTRNHPNGGTFLLTGTVTGKRLLVNKAFSWGKRQRHLNQAARKWKSHRCRG", "length": 292 }, "evidence": [ { "id": "A0A8V0ZFL9", "url": "https://omabrowser.org/oma/group/A0A8V0ZFL9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9" } ], "pmid": "" }, { "name": "non-canonical Wnt signaling pathway", "id": "GO:0035567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9" } ], "pmid": "" }, { "name": "regulation of multicellular organismal development", "id": "GO:2000026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "Wnt-protein binding", "id": "GO:0017147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZFL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9" }, { "id": "PS50038", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50038" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FZ", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 156, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZFL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFL9" }, { "id": "PS50189", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50189" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NTR", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 300, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFM5-1", "uniprot_ac": "A0A8V0ZFM5", "uniprot_id": "A0A8V0ZFM5_CHICK", "mass": { "chemical_mass": 46392.0, "monoisotopic_mass": 46392.0 }, "refseq": { "ac": "XP_040504148", "name": "cilia- and flagella-associated protein 73 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504148" }, "gene_names": [ { "name": "CFAP73", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM5" } ] }, { "name": "CFAP73", "type": "synonym", "evidence": [ { "id": "XP_040504148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504148" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 73", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM5/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 73 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040504148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504148" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040504148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504148" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZFM5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "770540", "url": "https://www.ncbi.nlm.nih.gov/gene/770540", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770540", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770540", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SIEMLYI", "url": "https://omabrowser.org/oma/group/SIEMLYI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFM5", "url": "https://www.orthodb.org/?gene=A0A8V0ZFM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN11", "url": "https://www.orthodb.org/?gene=A0A8V0ZN11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21683", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21683", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21683:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21683:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13863", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13863", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040504148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504148", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPRPAPPLPPRAAQDPDSAPEMSLGLEEHLSRAFQDKLRLQMVPAWDSASLLPSRRLLLKRREVVEVERALQAQREDFQQRMEHLAQRRQQLGQREEQLRDDTIKFNAFLKAMSARRQRAQQRAGEERARAAQRGAEALRLQQELERLQRRRERLGQRLQSLRVFGDFLQDVRAATGQFQDVPSMLAHFGALVEGRAVLLQQVEARQAALAQGRAQLQQCCEEADSELTSSNEEALQLHARLEAARSDVLKGETHWAQLQGAAAQTTLLLGQIRMAVLSLFQLTSMRLEVPKDVALEDTEAQLDVVSVTQQLWGWEGRGCPSDTEAPVSPAAALHAGPGCHLCRAGAVFSCACYHCHTPTASQSCHCASQPGIDGLRIQWSTKVTQHVQGRMKGNAPVQSLGHRCPPARHMDGQK", "length": 417, "header": "tr|A0A8V0ZFM5-1|A0A8V0ZFM5_CHICK Isoform 1 of Cilia and flagella associated protein 73 OS=Gallus gallus OX=9031 GN=CFAP73 PE=4 SV=1 CANONICAL=A0A8V0ZFM5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM5/entry#A0A8V0ZFM5-1", "sequence": { "sequence": "MAAPRPAPPLPPRAAQDPDSAPEMSLGLEEHLSRAFQDKLRLQMVPAWDSASLLPSRRLLLKRREVVEVERALQAQREDFQQRMEHLAQRRQQLGQREEQLRDDTIKFNAFLKAMSARRQRAQQRAGEERARAAQRGAEALRLQQELERLQRRRERLGQRLQSLRVFGDFLQDVRAATGQFQDVPSMLAHFGALVEGRAVLLQQVEARQAALAQGRAQLQQCCEEADSELTSSNEEALQLHARLEAARSDVLKGETHWAQLQGAAAQTTLLLGQIRMAVLSLFQLTSMRLEVPKDVALEDTEAQLDVVSVTQQLWGWEGRGCPSDTEAPVSPAAALHAGPGCHLCRAGAVFSCACYHCHTPTASQSCHCASQPGIDGLRIQWSTKVTQHVQGRMKGNAPVQSLGHRCPPARHMDGQK", "length": 417, "header": "tr|A0A8V0ZFM5-1|A0A8V0ZFM5_CHICK Isoform 1 of Cilia and flagella associated protein 73 OS=Gallus gallus OX=9031 GN=CFAP73 PE=4 SV=1 CANONICAL=A0A8V0ZFM5-1" }, "locus": { "chromosome": "15", "start_pos": 9909341, "end_pos": 9907200, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050874.1", "url": "https://www.ensembl.org/id/ENSGALT00010050874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030065.1", "url": "https://www.ensembl.org/id/ENSGALP00010030065.1" } ] } }, { "isoform_ac": "A0A8V0ZN11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM5/entry#A0A8V0ZN11-1", "sequence": { "sequence": "MAAPRPAPPLPPRAAQDPDSAPEMSLGLEEHLSRAFQDKLRLQMVPAWDSASLLPSRRLLLKRREVVEVERALQAQREDFQQRMEHLAQRRQQLGQREEQLRDDTIKFNAFLKAMSARRQRAQQRAGEERARAAQRGAEALRLQQELERLQRRRERLGQRLQSLRVFGDFLQDVRAATGQFQDVPSMLAHFGALVEGRAVLLQQVEARQAALAQGRAQLQQCCEEADSELTSSNEEALQLHARLEAARSDVLKGETHWAQLQGAAAQTTLLLGQIRMAVLSLFQLTSMRLEVPKDVALEDTEAQLDVLLLCMQDLAAICAELGLCSPVPATTATHPRRHRAVTVPPNQE", "length": 349, "header": "tr|A0A8V0ZN11-1|A0A8V0ZN11_CHICK Computationally mapped isoform of Cilia and flagella associated protein 73 OS=Gallus gallus OX=9031 GN=CFAP73 PE=4 SV=1 CANONICAL=A0A8V0ZFM5-1" }, "locus": { "chromosome": "15", "start_pos": 9909213, "end_pos": 9907200, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050873.1", "url": "https://www.ensembl.org/id/ENSGALT00010050873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030064.1", "url": "https://www.ensembl.org/id/ENSGALP00010030064.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770540", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770540", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NFT4-1", "protein_name": "Cilia- and flagella-associated protein 73", "gene_name": "CFAP73", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVPWEEYFRLALQEKLSTKLPEQAEDHVPPVLRLLEKRQELVDADQALQAQKEVFRTKTAALKQRWEQLEQKERELKGSFIRFDKFLQDSEARRNRALRRAAEERHQAGRREVEALRLWTQLQELRREHARLQRRLKRLEPCARLLEQALELLPGFQEVPELVARFDGLAETQAALRLREREQLAELEAARARLQQLRDAWPDEVLAQGQRRAQLQERLEAARERTLQWESKWIQIQNTAAEKTLLLGRSRMAVLNLFQLVCQHQGQPPTLDIEDTEGQLEHVKLFMQDLSAMLAGLGQAEPAAPAS", "length": 308 }, "evidence": [ { "id": "A0A8V0ZFM5", "url": "https://omabrowser.org/oma/group/A0A8V0ZFM5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { 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"o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZH40-1", "uniprot_ac": "A0A8V0ZH40", "uniprot_id": "A0A8V0ZH40_CHICK", "mass": { "chemical_mass": 113161.0, "monoisotopic_mass": 113161.0 }, "refseq": { "ac": "XP_004945346", "name": "centriolar coiled-coil protein of 110 kDa isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945346" }, "gene_names": [ { "name": "CCP110", "type": "recommended", "evidence": [ { "id": "A0A8V0ZH40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40" } ] }, { "name": "CCP110", "type": "synonym", "evidence": [ { "id": "XP_004945346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945346" } ] } ], "protein_names": [ { "name": "Centriolar coiled-coil protein 110", "type": "synonym", "evidence": [ { "id": "A0A8V0ZH40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40/entry#names_and_taxonomy" } ] }, { "name": "centriolar coiled-coil protein of 110 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004945346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945346" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945346.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945346" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCP110", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40", "locus": { "chromosome": "14", "start_pos": 8558299, "end_pos": 8543115, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021058", "url": "https://www.ensembl.org/id/ENSGALG00010021058" } ] } } ], "crossref": [ { "id": "A0A8V0ZH40", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZH40", "database": "AlphaFoldDB", "categories": [] }, { "id": "416613", "url": "https://www.ncbi.nlm.nih.gov/gene/416613", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416613", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416613", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFKSNGV", "url": "https://omabrowser.org/oma/group/QFKSNGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFT7", "url": "https://www.orthodb.org/?gene=A0A8V0ZFT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH40", "url": "https://www.orthodb.org/?gene=A0A8V0ZH40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13594", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13594", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13594:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13594:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013424", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004945346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945346", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMEDYETFCKKHLSRIQEEATKGENSSTSLDRNVSLIQFHGVPVLSPLLSFEKRKEIQQYRQKALDLETWRQNSHKRALLNRVQEILENIQNRKVSGKSDVNTWDAENTCPDSDSKALTDLAAVSDANLPCSPERHCSVQLEKSQELLPPDSMQQVTSNATEVGKPAEENVPSKESGSHFSRDVPCPRAASPDSVQSKLVSPALQKQEGQGVPSSDKEVQDPYAVSLQNLMKKSREYIEKEQSRRSSKSSSKKSMNESHSDKENDAVKTSDPVKERVKLTGRSSTALPLDKPCLNKSNAHIQGASTHTSNTSMSTLSSFSKVDIPMRVGTPPLVDSDSDEEFKNTSTIDRDSSIVRSLTGSYTKLPSPEPSMSPKMHRRRPRPLSMGHIVINNPVNAYELSPKGKGRAMDLIMQDIADKNNVSESVPKFMMDFSMLCPSRVPGVLRSSSGPSDGLLVGKPNRHSFGHSEGKGTLSAAMEGQVVMDNRGPYKVETGTVGSKLNEPFSINQSTVTQKLLAVNETKASSLQENTKSPVELNKSYDVESPSPLLMQSKSMHQQMDTPSIPPANEQFLENSFEKVKRRLDLDTDDCQKDNNPCVVTVGMEEQERQWLQEQKYPVTSVYITKNAASDSSMAKEEILKTKMLAFEEMRKRLEEQHAQQLSILIAEQEREQEKLQKELEEQERKGKKIATTEIEISKVNINSRMELEWRKSESGLVESVQSQLETIHNANSTSIGFAHTTSPNTFTSTSETSFFLWGPSGSGVIKTSVSRPSNRIKTRWTQIFTPEIQMKFDKITAVAKGFLTRRLLQTEKLKHLKQTVKDTMEFIRNFQSEAPLKRGSVSAQDASLHERVMAQLRAALYDIHDIFFTMEASERMNILRHDREVRKEKMLRQMDKVKSPRERATLSTATQKSLDRKKYMKASEMGMPSKKIVIKQRSPESRVLQPNQGQNAPVHRLLCRQGTPKTSMKGVEQNRKKASESRVSNKAVSGAYAGRTQRKKPNVVTI", "length": 1008, "header": "tr|A0A8V0ZH40-1|A0A8V0ZH40_CHICK Isoform 1 of Centriolar coiled-coil protein 110 OS=Gallus gallus OX=9031 GN=CCP110 PE=4 SV=1 CANONICAL=A0A8V0ZH40-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40/entry#A0A8V0ZFT7-1", "sequence": { "sequence": "MKMEDYETFCKKHLSRIQEEATKGENSSTSLDRNVSLIQFHGVPVLSPLLSFEKRKEIQQYRQKALDLETWRQNSHKRALLNRVQEILENIQNRKVSGKSDVNTWDAENTCPDSDSKALTDLAAVSDANLPCSPERHCSVQLEKSQELLPPDSMQQVTSNATEVGKPAEENVPSKESGSHFSRDVPCPRAASPDSVQSKLVSPALQKQEGQGVPSSDKEVQDPYAVSLQNLMKKSREYIEKEQSRRSSKSSSKKSMNESHSDKENDAVKTSDPVKERVKLTGRSSTALPLDKPCLNKSNAHIQGASTHTSNTSMSTLSSFSKVDIPMRVGTPPLVDSDSDEEFKNTSTIDRDSSIVRSLTGSYTKLPSPEPSMSPKMHRRRPRPLSMGHIVINNPVNAYELSPKGKGRAMDLIMQDIADKNNVSESVPKFMMDFSMLCPSRVPGVLRSSSGPSDGLLVGKPNRHSFGHSEGKGTLSAAMEGQVVMDNRGPYKVETGTVGSKLNEPFSINQSTVTQKLLAVNETKASSLQENTKSPVELNKSYDVESPSPLLMQSKSMHQQMDTPSIPPANEQFLENSFEKVKRRLDLDTDDCQKDNNPCVVTVGMEEQERQWLQEQKYPVTSVYITKNAASDSSMAKEEILKTKMLAFEEMRKRLEEQHAQQLSILIAEQEREQEKLQKELEEQERKGKKIATTEIEISKVNINSRMELEWRKSESGLVESVQSQLETIHNANSTSIGFAHTTSPNTFTSTSETSFFLWGPSGSGVIKTSVSRPSNRIKTRWTQIFTPEIQMKFDKITAVAKGFLTRRLLQTEKLKHLKQTVKDTMEFIRNFQSEAPLKRGSVSAQDASLHERVMAQLRAALYDIHDIFFTMEASERMNILRHDREVRKEKMLRQMDKVKSPRERATLSTATQKSLDRKKYMKASEMGMPSKKIVIKQRSPESRVLQPNQGQNAPVHRLLCRQGSICRKNPKKEAKCCDNLRRQHSLG", "length": 988, "header": "tr|A0A8V0ZFT7-1|A0A8V0ZH40_CHICK Computationally mapped isoform of Centriolar coiled-coil protein 110 OS=Gallus gallus OX=9031 GN=CCP110 PE=4 SV=1 CANONICAL=A0A8V0ZH40-1" }, "locus": { "chromosome": "14", "start_pos": 8558147, "end_pos": 8543756, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050946.1", "url": "https://www.ensembl.org/id/ENSGALT00010050946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030137.1", "url": "https://www.ensembl.org/id/ENSGALP00010030137.1" } ] } }, { "isoform_ac": "A0A8V0ZH40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40/entry#A0A8V0ZH40-1", "sequence": { "sequence": "MKMEDYETFCKKHLSRIQEEATKGENSSTSLDRNVSLIQFHGVPVLSPLLSFEKRKEIQQYRQKALDLETWRQNSHKRALLNRVQEILENIQNRKVSGKSDVNTWDAENTCPDSDSKALTDLAAVSDANLPCSPERHCSVQLEKSQELLPPDSMQQVTSNATEVGKPAEENVPSKESGSHFSRDVPCPRAASPDSVQSKLVSPALQKQEGQGVPSSDKEVQDPYAVSLQNLMKKSREYIEKEQSRRSSKSSSKKSMNESHSDKENDAVKTSDPVKERVKLTGRSSTALPLDKPCLNKSNAHIQGASTHTSNTSMSTLSSFSKVDIPMRVGTPPLVDSDSDEEFKNTSTIDRDSSIVRSLTGSYTKLPSPEPSMSPKMHRRRPRPLSMGHIVINNPVNAYELSPKGKGRAMDLIMQDIADKNNVSESVPKFMMDFSMLCPSRVPGVLRSSSGPSDGLLVGKPNRHSFGHSEGKGTLSAAMEGQVVMDNRGPYKVETGTVGSKLNEPFSINQSTVTQKLLAVNETKASSLQENTKSPVELNKSYDVESPSPLLMQSKSMHQQMDTPSIPPANEQFLENSFEKVKRRLDLDTDDCQKDNNPCVVTVGMEEQERQWLQEQKYPVTSVYITKNAASDSSMAKEEILKTKMLAFEEMRKRLEEQHAQQLSILIAEQEREQEKLQKELEEQERKGKKIATTEIEISKVNINSRMELEWRKSESGLVESVQSQLETIHNANSTSIGFAHTTSPNTFTSTSETSFFLWGPSGSGVIKTSVSRPSNRIKTRWTQIFTPEIQMKFDKITAVAKGFLTRRLLQTEKLKHLKQTVKDTMEFIRNFQSEAPLKRGSVSAQDASLHERVMAQLRAALYDIHDIFFTMEASERMNILRHDREVRKEKMLRQMDKVKSPRERATLSTATQKSLDRKKYMKASEMGMPSKKIVIKQRSPESRVLQPNQGQNAPVHRLLCRQGTPKTSMKGVEQNRKKASESRVSNKAVSGAYAGRTQRKKPNVVTI", "length": 1008, "header": "tr|A0A8V0ZH40-1|A0A8V0ZH40_CHICK Isoform 1 of Centriolar coiled-coil protein 110 OS=Gallus gallus OX=9031 GN=CCP110 PE=4 SV=1 CANONICAL=A0A8V0ZH40-1" }, "locus": { "chromosome": "14", "start_pos": 8558124, "end_pos": 8543756, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050948.1", "url": "https://www.ensembl.org/id/ENSGALT00010050948.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030139.1", "url": "https://www.ensembl.org/id/ENSGALP00010030139.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416613", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416613", "resource": "KEGG Pathway" }, { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" }, { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" }, { "id": "R-GGA-9013424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "resource": "Reactome", "description": "RHOV GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZT05-1", "protein_name": "Centriolar coiled-coil protein 110", "gene_name": "Ccp110", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEYEKFCEKALARAQEASLSTDSFLPAQAESVSLIRFHGVAVLSPLLTIEKREKIQQEKQKALDVQTRKQANRKKALLTRVQEILENVQVRKAPNASDFDQWATETIASNSEVTGLSVPVTVPSDLLSPTEHCTSGKLGKTTGLLPVNNEDQQSPERMGLPKDSEVFGSLKQCESPGSRWAENGAAPRLSSASSQETVISDDPLLAKEEQEPSCLAEVTPDPYIISLQNLMKRSKEYVEREQSSWSLRSSLKKSVHETHSDKENDAAKASDCVKEKAPPMPVGRHCGSAIPDKPSLNKSNVLLQGASQASSLGTSVLASFLKTDLPVGTGPPTVPDAESDFKVIPTFVTENKVKSLIGPYAKLPSPEPSMSPTMHRRHSRSSSACQILINNPVNACELSPKGKEEAVDRIAPAAAETNESEIVPKPPTDLTGVGSSKVSATKVMSDTIREMVMGKPSQVHQALGNQLGNNVTVEQFAMEGPFIPDGRGMQKVDGTCIAVPKLHELQPTSQCVSSQTLEDACGLKAASVLAKNSCNVQMELNKSYDVKRPSPLLMQTQNSRQQMDTPPVPRGNEQFVDNSFEKVKRRLDLDVDSLQKENCPHILTAGSAEQERERPPERRYPKGSVYGNKNKMLETSPKEGQELLKSKMLAFEEMRKRLEEQHVQQLSLLIAEQEREQEQLQKEIEEQEKMLKEKAVTTDVSGLNSALELEWRKRSDPAFLETMLSQVDSLQTSNNSGFLSSALQYSFGSASEVPLYLRGSLTSGVTKLSVTRPFGRAQPKWSQVFSPEIQAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMRSPRVALSVATQKSLDRKKFMKVAEMGMANKKFLLKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGAYAGKTQRKRPNVATI", "length": 1007 }, "evidence": [ { "id": "A0A8V0ZH40", "url": "https://omabrowser.org/oma/group/A0A8V0ZH40/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGQ5-1", "protein_name": "Centriolar coiled-coil protein 110", "gene_name": "CCP110", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEEYEKFCEKSLSRIQEASLSTESFLPVQSESISLIRFHGVAVLSPLLNIEKRKEMQQEKQKALDVEARRQVNRKKALLSRVQEILENVQVRKAPDASDFHQWETETVYSNSEVRNLNVPATLPNILPSPTEHSTLAEFEKITGILPLNNEDRFKSNRIDLARDSEELSYLKQCDSSNISQAENEASLKTSSTAAQETLTSDVLFPTNEEQDPSLLEEVTPDPYIMSLQNLMKKSKEYIEREQSRRSLRSSVKRSVNESHSDKENDAVKVTDNGKEKSPLIGKHCGSVIPDKPSLNKSNVLLQGAFTQASSMNTSVLGNFSKVDISIRTGHTTVLETDSNFQGIPTFVTENNVIKSLTGSYAKIPSPEPSLSPKMHRRRSRPSSACHILINNPINASELSPKGKEQAVELVVQETDEKTNVPETVPKLPVCSSKVYVSKNTEAIQEMVLGKSNQVCQPSGNQLENKVIHGLAIMEGQLISDARGPHRVDSTCTAGERLHEPYATRECVLSQNFGSVSGVKSTNVLEKNSCNLQMELNKSYDVKNPSPLLMQNQNTRQQMDTPTVSCGKEQFLDNSFGKVKRRLDLDIDNLQKENYPYVVTTGIAEQERQHLPEKRYSKGSVYIKNKMLESSSKEGEEILKSKILAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKDIEEQEKMLKEKTIITAEASELDISNAVDFGWRKISDSGLLDTVLSQVDSLHTSNSNSSGFTSSALQHSFASANEVPFYLWGSSSSGLTKLSVTRPFGRAKTKWSQVFSPEVQAKLNKVTAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPSKKFLVKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKSSQSRVPSRAPVSGVYAGKIQRKRPNVATI", "length": 1006 }, "evidence": [ { "id": "A0A8V0ZH40", "url": "https://omabrowser.org/oma/group/A0A8V0ZH40/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O43303-1", "protein_name": "Centriolar coiled-coil protein of 110 kDa", "gene_name": "CCP110", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEYEKFCEKSLARIQEASLSTESFLPAQSESISLIRFHGVAILSPLLNIEKRKEMQQEKQKALDVEARKQVNRKKALLTRVQEILDNVQVRKAPNASDFDQWEMETVYSNSEVRNLNVPATFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKTDGIDLARDSEGFNSPKQCDSSNISHVENEAFPKTSSATPQETLISDGPFSVNEQQDLPLLAEVIPDPYVMSLQNLMKKSKEYIEREQSRRSLRGSINRIVNESHLDKEHDAVEVADCVKEKGQLTGKHCVSVIPDKPSLNKSNVLLQGASTQASSMSMPVLASFSKVDIPIRTGHPTVLESNSDFKVIPTFVTENNVIKSLTGSYAKLPSPEPSMSPKMHRRRSRTSSACHILINNPINACELSPKGKEQAMDLIIQDTDENTNVPEIMPKLPTDLAGVCSSKVYVGKNTSEVKEDVVLGKSNQVCQSSGNHLENKVTHGLVTVEGQLTSDERGAHIMNSTCAAMPKLHEPYASSQCIASPNFGTVSGLKPASMLEKNCSLQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQKENCPYVITSGITEQERQHLPEKRYPKGSGFVNKNKMLGTSSKESEELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEWRKISDSSLLETMLSQADSLHTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLSVTRPFGRAKTRWSQVFSLEIQAKFNKITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKEKMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPNKKFLVKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRVPVSGVYAGKIQRKRPNVATI", "length": 1012 }, "evidence": [ { "id": "A0A8V0ZH40", "url": "https://omabrowser.org/oma/group/A0A8V0ZH40/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TSH4-1", "protein_name": "Centriolar coiled-coil protein of 110 kDa", "gene_name": "Ccp110", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEYEEFCEKALGRAQEASLSTGSFLPAQAESVSLIRFHGVAVLSPLLTIEKRKKIQEEKQKALDVQSRKQANRKKALLTRVQEILENVQVRKAPNASDFDQWATETIYSNPEVTDLNVPVRVPNSLPSPTEHCTSVKLEKITGLLPVNNEDQQTPKRVGLPGDSEVSGSLRQCESPESRQAEDGAALRLSSASPQETIISDVLGKEEQDPSCLAEVTPDPYIMSLQNLMKRSKEYVERELSSRSLRNSLKRSVNETHSDRENDAAKASDCVKEKAPPMPIGRHCGSAIPDKPSLNKSNVLLQGASQASSMGTAGLASFSKIDLPAGAAPPAAPDAGSDFTVIPTFVTENKVKSLKGPYAKLPSPEPSMSPTMHRRHSRSASACQILINNPVNACELSPKGKEEAVDRTAPAAAETTNESETVPKSPTDLTGVCSSNVSATKITSESTREMVVGKPSQRQQALGAHLGNNVTVERSAMEGPFIADDRGAQKVDGTCMAVPKLHELQPSSQCVSSQTLEDVCELKSASLLAKNSCNLQMELNKSYDVKHPSPLLTQTQTSRQQMDTPPVFRGNEQFVDNSFEKVKRRLDLDVDSLQKENCPYIITAGVAEQERDRLLERRYPKGFVHINKNKMLETSPKEGQELLKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQEQLQKEIEEQEKMLKEKAVTTDVSDLNSALEWRQRTDSALLETMLSQVDSLQTSNNSGFITSALQYSFGSAGEAPFYLWGSLTSGVTRVSGTRPCGRAQAKWSQVFNPEIHAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMKSPRVALSVATQKSLDRKKFMKVAEMGMPNKKFLLKQNPSETRVLQPNQGQNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGAYAGKTQRKRPNVATI", "length": 1004 }, "evidence": [ { "id": "A0A8V0ZH40", "url": "https://omabrowser.org/oma/group/A0A8V0ZH40/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40" } ], "pmid": "" }, { "name": "negative regulation of cilium assembly", "id": "GO:1902018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40" } ], "pmid": "" }, { "name": "positive regulation of cilium assembly", "id": "GO:0045724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40" } ], "pmid": "" }, { "name": "ciliary basal body organization", "id": "GO:0032053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032053", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 733, "end_pos": 735, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 311, "end_pos": 313 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 509, "end_pos": 511 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 733, "end_pos": 735 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFT8-1", "uniprot_ac": "A0A8V0ZFT8", "uniprot_id": "A0A8V0ZFT8_CHICK", "mass": { "chemical_mass": 20969.0, "monoisotopic_mass": 20969.0 }, "refseq": {}, "gene_names": [ { "name": "LOC107054158", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8" } ] } ], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107054158", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZFT8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFT8", "url": "https://www.orthodb.org/?gene=A0A8V0ZFT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL58", "url": "https://www.orthodb.org/?gene=A0A8V0ZL58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMX5", "url": "https://www.orthodb.org/?gene=A0A8V0ZMX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZFT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRHQEHRRQSWCNKHPVSPSFPDSLSNSACRRAVTAADCGSNTICGCFEDTEPEREAGGQQRALVKELRKAKKDRLTLGSVFPPCSVFQLCLPQREMSCCRPCVPSPCGASGPTPLASSCSEPCVARCADSTVVIEASPVVVTLPGPILTSFPQSTAVGSSLSAAVGSSLSTAGVPISSGGSLGLGGSGLCLPRPRCSFNC", "length": 202, "header": "tr|A0A8V0ZFT8-1|A0A8V0ZFT8_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC107054158 PE=3 SV=1 CANONICAL=A0A8V0ZFT8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8/entry#A0A8V0ZFT8-1", "sequence": { "sequence": "MLRHQEHRRQSWCNKHPVSPSFPDSLSNSACRRAVTAADCGSNTICGCFEDTEPEREAGGQQRALVKELRKAKKDRLTLGSVFPPCSVFQLCLPQREMSCCRPCVPSPCGASGPTPLASSCSEPCVARCADSTVVIEASPVVVTLPGPILTSFPQSTAVGSSLSAAVGSSLSTAGVPISSGGSLGLGGSGLCLPRPRCSFNC", "length": 202, "header": "tr|A0A8V0ZFT8-1|A0A8V0ZFT8_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN=LOC107054158 PE=3 SV=1 CANONICAL=A0A8V0ZFT8-1" }, "locus": { "chromosome": "10", "start_pos": 712374, "end_pos": 711769, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053370.1", "url": "https://www.ensembl.org/id/ENSGALT00010053370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032170.1", "url": "https://www.ensembl.org/id/ENSGALP00010032170.1" } ] } }, { "isoform_ac": "A0A8V0ZG59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8/entry#A0A8V0ZG59-1", "sequence": { "sequence": "MSCCRPCVPSPCGASGPTPLASSCSEPCVARCADSTVVIEASPVVVTLPGPILTSFPQSTAVGSSLSAAVGSSLSTAGVPISSGGSLGLGGSGLCLPRPRC", "length": 101, "header": "tr|A0A8V0ZG59-1|A0A8V0ZG59_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZFT8-1" }, "locus": { "chromosome": "10", "start_pos": 753603, "end_pos": 753301, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053601.1", "url": "https://www.ensembl.org/id/ENSGALT00010053601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032296.1", "url": "https://www.ensembl.org/id/ENSGALP00010032296.1" } ] } }, { "isoform_ac": "A0A8V0ZL58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8/entry#A0A8V0ZL58-1", "sequence": { "sequence": "MSCCRPCVPSPCGASGPTPLASSCSEPCVARCADSTVVIEASPVVVTLPGPILTSFPQSTAVGSSLSAAVGSSLSTAGVPISSGGSLGLGGSGLCLPRPRCSFNC", "length": 105, "header": "tr|A0A8V0ZL58-1|A0A8V0ZL58_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN=LOC107054158 PE=3 SV=1 CANONICAL=A0A8V0ZFT8-1" }, "locus": { "chromosome": "10", "start_pos": 753615, "end_pos": 753301, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053599.1", "url": "https://www.ensembl.org/id/ENSGALT00010053599.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032294.1", "url": "https://www.ensembl.org/id/ENSGALP00010032294.1" } ] } }, { "isoform_ac": "A0A8V0ZMX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8/entry#A0A8V0ZMX5-1", "sequence": { "sequence": "MSTRIRTGSRWSLTEQAGVPHSIFTAVIFFFELCLPQREMSCCRPCVPSPCGASGPTPLASSCSEPCVARCADSTVVIEASPVVVTLPGPILTSFPQSTAVGSSLSAAVGSSLSTAGVPISSGGSLGLGGSGLCLPRPRCSFNC", "length": 144, "header": "tr|A0A8V0ZMX5-1|A0A8V0ZMX5_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN=LOC107054158 PE=3 SV=1 CANONICAL=A0A8V0ZFT8-1" }, "locus": { "chromosome": "10", "start_pos": 712374, "end_pos": 711484, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053375.1", "url": "https://www.ensembl.org/id/ENSGALT00010053375.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032174.1", "url": "https://www.ensembl.org/id/ENSGALP00010032174.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 115, "start_aa": "Thr", "end_pos": 115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr115", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 36, "start_aa": "Thr", "end_pos": 36, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr36", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 36, 115 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFT9-1", "uniprot_ac": "A0A8V0ZFT9", "uniprot_id": "A0A8V0ZFT9_CHICK", "mass": { "chemical_mass": 65033.0, "monoisotopic_mass": 65033.0 }, "refseq": { "ac": "XP_046800614", "name": "mucolipin-3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046800614" }, "gene_names": [ { "name": "MCOLN3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT9" } ] }, { "name": "MCOLN3", "type": "synonym", "evidence": [ { "id": "XP_046800614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046800614" } ] } ], "protein_names": [ { "name": "Mucolipin TRP cation channel 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT9/entry#names_and_taxonomy" } ] }, { "name": "mucolipin-3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_046800614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046800614" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046800614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046800614" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCOLN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT9", "locus": { "chromosome": "8", "start_pos": 16117261, "end_pos": 16093974, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020776", "url": "https://www.ensembl.org/id/ENSGALG00010020776" } ] } } ], "crossref": [ { "id": "A0A8V0ZFT9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFT9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21072", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21072", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429091", "url": "https://www.ncbi.nlm.nih.gov/gene/429091", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429091", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429091", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR12127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12127:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12127:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046800614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046800614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZFT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCRAMETPEVAVSSCSARDDEGLCSYGQHLLLPQELVAEDQLRRKLKFFFMNPCEKFWARGRKPWKLGIQLLKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQTDVYDQIFFAINQYLQLPNISVGNHAYEKKGAEETALAVCQQFYKQGTICPGNDTFDIDPEIVTDCLYIEPMMSLDNRTVGKHNLNFTLDFHRLVAVQLMFNLKAINLQTVRHHELPDCYDFTLTIVFDNKAHSGRIKISLDNDIEIRECKDWHVSGSIQKNTHYMMIFDAFVILICLSSLILCTRSVVKGIRLQREFVSFFLYYYKKEVSYNDQMEFVNGWYILIMVSDVLTIVGSTLKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFQKYNLLILTLRAALPNVMRFCCCAAMIYLGYCFCGWIVLGPYHVKFRSLNVVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMVLSLFIALITDTYETIKHYQQDGFPETELQRFISQCKDLPNSGRYRLEEEGSVSLFCCCSGPSEHI", "length": 562, "header": "tr|A0A8V0ZFT9-1|A0A8V0ZFT9_CHICK Isoform 1 of Mucolipin TRP cation channel 3 OS=Gallus gallus OX=9031 GN=MCOLN3 PE=4 SV=1 CANONICAL=A0A8V0ZFT9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT9/entry#A0A8V0ZFT9-1", "sequence": { "sequence": "MCRAMETPEVAVSSCSARDDEGLCSYGQHLLLPQELVAEDQLRRKLKFFFMNPCEKFWARGRKPWKLGIQLLKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQTDVYDQIFFAINQYLQLPNISVGNHAYEKKGAEETALAVCQQFYKQGTICPGNDTFDIDPEIVTDCLYIEPMMSLDNRTVGKHNLNFTLDFHRLVAVQLMFNLKAINLQTVRHHELPDCYDFTLTIVFDNKAHSGRIKISLDNDIEIRECKDWHVSGSIQKNTHYMMIFDAFVILICLSSLILCTRSVVKGIRLQREFVSFFLYYYKKEVSYNDQMEFVNGWYILIMVSDVLTIVGSTLKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFQKYNLLILTLRAALPNVMRFCCCAAMIYLGYCFCGWIVLGPYHVKFRSLNVVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMVLSLFIALITDTYETIKHYQQDGFPETELQRFISQCKDLPNSGRYRLEEEGSVSLFCCCSGPSEHI", "length": 562, "header": "tr|A0A8V0ZFT9-1|A0A8V0ZFT9_CHICK Isoform 1 of Mucolipin TRP cation channel 3 OS=Gallus gallus OX=9031 GN=MCOLN3 PE=4 SV=1 CANONICAL=A0A8V0ZFT9-1" }, "locus": { "chromosome": "8", "start_pos": 16116027, "end_pos": 16096757, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050274.1", "url": "https://www.ensembl.org/id/ENSGALT00010050274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029709.1", "url": "https://www.ensembl.org/id/ENSGALP00010029709.1" } ] } }, { "isoform_ac": "A0A8V0ZM21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT9/entry#A0A8V0ZM21-1", "sequence": { "sequence": "METPEVAVSSCSARDDEGLCSYGQHLLLPQELVAEDQLRRKLKFFFMNPCEKFWARGRKPWKLGIQLLKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQTDVYDQIFFAINQYLQLPNISVGNHAYEKKGAEETALAVCQQFYKQGTICPGNDTFDIDPEIVTDCLYIEPMMSLDNRTVGKHNLNFTLDFHRLVAVQLMFNLKAINLQTVRHHELPDCYDFTLTIVFDNKAHSGRIKISLDNDIEIRECKDWHVSGSIQKNTHYMMIFDAFVILICLSSLILCTRSVVKGIRLQREFVSFFLYYYKKEVSYNDQMEFVNGWYILIMVSDVLTIVGSTLKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFQKYNLLILTLRAALPNVMRFCCCAAMIYLGYCFCGWIVLGPYHVKFRSLNVVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMVLSLFIALITDTYETIKHYQQDGFPETELQRFISQCKDLPNSGRYRLEEEGSVSLFCCCSGEEMGACFGTRTEQNLQRHRLELRALVPTGCLTWDESVG", "length": 591, "header": "tr|A0A8V0ZM21-1|A0A8V0ZM21_CHICK Computationally mapped isoform of Mucolipin TRP cation channel 3 OS=Gallus gallus OX=9031 GN=MCOLN3 PE=4 SV=1 CANONICAL=A0A8V0ZFT9-1" }, "locus": { "chromosome": "8", "start_pos": 16115280, "end_pos": 16102187, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050266.1", "url": "https://www.ensembl.org/id/ENSGALT00010050266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029706.1", "url": "https://www.ensembl.org/id/ENSGALP00010029706.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429091", "resource": "KEGG Pathway" }, { "id": "R-GGA-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": 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{ "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZG22-1", "uniprot_ac": "A0A8V0ZG22", "uniprot_id": "A0A8V0ZG22_CHICK", "mass": { "chemical_mass": 18439.0, "monoisotopic_mass": 18439.0 }, "refseq": { "ac": "XP_046756034", "name": "hydroxyacyl-thioester dehydratase type 2, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756034" }, "gene_names": [ { "name": "HTD2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZG22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22" } ] }, { "name": "HTD2", "type": "synonym", "evidence": [ { "id": "XP_046756034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756034" } ] } ], "protein_names": [ { "name": "Ribonuclease P/MRP subunit p14", "type": "synonym", "evidence": [ { "id": "A0A8V0ZG22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22/entry#names_and_taxonomy" } ] }, { "name": "hydroxyacyl-thioester dehydratase type 2, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_046756034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756034" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046756034", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756034" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HTD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22", "locus": { "chromosome": "12", "start_pos": 11975927, "end_pos": 11972439, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020806", "url": "https://www.ensembl.org/id/ENSGALG00010020806" } ] } } ], "crossref": [ { "id": "cd03449", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03449", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "112533344", "url": "https://www.ncbi.nlm.nih.gov/gene/112533344", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GCVFLHQ", "url": "https://omabrowser.org/oma/group/GCVFLHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFV6", "url": "https://www.orthodb.org/?gene=A0A8V0ZFV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG22", "url": "https://www.orthodb.org/?gene=A0A8V0ZG22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43437", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43437", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43437:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43437:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01575", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01575", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-75105", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046756034", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756034", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLLRCGISRGDFRHGASTKLVVTNLLLGCPLLQNLHIKVGDKAELSRVFTQNDVVTFSHLTGDTNPLHLSEDFAKKTKFGRTVVHGVLINGLISAVLGTKMPGQGCVFLSQEIRFPAPLYTGEEVIAAVQVRRLRSSVAHIAVSCKVRESGKTVMEGVVKVMVPASSSC", "length": 171, "header": "tr|A0A8V0ZG22-1|A0A8V0ZG22_CHICK Isoform 1 of Ribonuclease P/MRP subunit p14 OS=Gallus gallus OX=9031 GN=HTD2 PE=4 SV=1 CANONICAL=A0A8V0ZG22-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22/entry#A0A8V0ZFV6-1", "sequence": { "sequence": "MERAEPPAAAYERRVLLSAAQHWYLRVRLELPDGAARPGAPQLKQLVVAALRELHGEVGAALPVDVLAYEEKSLCAILRVISSGLVKLWSALTLQGSYQNRRCAFRVLQLGTAGSWSCTERGRLDCQKVLEMLLLLRCGISRGDFRHGASTKLVVTNLLLGCPLLQNLHIKVGDKAELSRVFTQNDVVTFSHLTGDTNPLHLSEDFAKKTKFGRTVVHGVLINGLISAVLGTKMPGQGCVFLSQEIRFPAPLYTGEEVIAAVQVRRLRSSVAHIAVSCKVRESGKTVMEGVVKVMVPASSSC", "length": 302, "header": "tr|A0A8V0ZFV6-1|A0A8V0ZG22_CHICK Computationally mapped isoform of Ribonuclease P/MRP subunit p14 OS=Gallus gallus OX=9031 GN=HTD2 PE=4 SV=1 CANONICAL=A0A8V0ZG22-1" }, "locus": { "chromosome": "12", "start_pos": 11974463, "end_pos": 11972462, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050324.1", "url": "https://www.ensembl.org/id/ENSGALT00010050324.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029724.1", "url": "https://www.ensembl.org/id/ENSGALP00010029724.1" } ] } }, { "isoform_ac": "A0A8V0ZG22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22/entry#A0A8V0ZG22-1", "sequence": { "sequence": "MLLLLRCGISRGDFRHGASTKLVVTNLLLGCPLLQNLHIKVGDKAELSRVFTQNDVVTFSHLTGDTNPLHLSEDFAKKTKFGRTVVHGVLINGLISAVLGTKMPGQGCVFLSQEIRFPAPLYTGEEVIAAVQVRRLRSSVAHIAVSCKVRESGKTVMEGVVKVMVPASSSC", "length": 171, "header": "tr|A0A8V0ZG22-1|A0A8V0ZG22_CHICK Isoform 1 of Ribonuclease P/MRP subunit p14 OS=Gallus gallus OX=9031 GN=HTD2 PE=4 SV=1 CANONICAL=A0A8V0ZG22-1" }, "locus": { "chromosome": "12", "start_pos": 11974463, "end_pos": 11973951, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050316.1", "url": "https://www.ensembl.org/id/ENSGALT00010050316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029720.1", "url": "https://www.ensembl.org/id/ENSGALP00010029720.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-75105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75105", "resource": "Reactome", "description": "Fatty acyl-CoA biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VKF6-1", "protein_name": "Hydroxyacyl-thioester dehydratase type 2", "gene_name": "HTD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPVISSHCLWWGRLQRGICLNWLALNRMHSQHMHIRVGDRAELSRAFTQRDVAAFSELTGDVNPLHLDEDFAKHTRFGKTIVHGVLINGLISALLGTKMPGPGCIFLSQEINFPAPLYVGEVVLASAEVKKLKRFIAVIAVSCFVLESKKTVMEGWVKVMVPEAPKS", "length": 168 }, "evidence": [ { "id": "A0A8V0ZG22", "url": "https://omabrowser.org/oma/group/A0A8V0ZG22/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A0M8-1", "protein_name": "Ribonuclease P/MRP subunit p14", "gene_name": "Rpp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKMWSGLQRRLWQHRVVPTGQCFRCVHMKVGDRAELSRAFTQQDVATFSELTGDANPLHLSEDFAKHTRFGKTVVHGVLINGLISALLGTKMPGPGCVFLSQEIKFPAPLYIGEVVLASAEVKRLKQSVAVVEVSCCVIESKKTVMEGLVKIMVPGAPRS", "length": 161 }, "evidence": [ { "id": "A0A8V0ZG22", "url": "https://omabrowser.org/oma/group/A0A8V0ZG22/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P86397-1", "protein_name": "Hydroxyacyl-thioester dehydratase type 2, mitochondrial", "gene_name": "HTD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFPLISSHHLWWGGLRRTVCLNLPVLTLQHFQHMHIKVGDRAELRRAFTQTDVATFSELTGDVNPLHLNEDFAKHTKFGNTIVHGVLINGLISALLGTKMPGPGCVFLSQEISFPAPLYIGEVVLASAEVKKLKRFIAIIAVSCSVIESKKTVMEGWVKVMVPEASKS", "length": 168 }, "evidence": [ { "id": "A0A8V0ZG22", "url": "https://omabrowser.org/oma/group/A0A8V0ZG22/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQH8-1", "protein_name": "Ribonuclease P protein subunit p14", "gene_name": "Rpp14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPATAYERVVYKSPSEYHYMKVCLEFQEHGVGLNVAQFKQLLVSALRDLFGEVGAALPVDVLTYDEKTLSAILRICSSGLVKLWSSLTLFGAYKSKKCAFRVIQVSPFLLALSGNSREQVLD", "length": 122 }, "evidence": [ { "id": "A0A8V0ZG22", "url": "https://omabrowser.org/oma/group/A0A8V0ZG22/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FJI2-1", "protein_name": "3-hydroxyacyl-[acyl-carrier-protein] dehydratase, mitochondrial", "gene_name": "MTHD", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MLAKTVFPRGLLVLRSFSSVASKTLLKVGDVLRETRVFSSEDIKAYAEVSHDWNPLHFDPESARKAGFENRLVHGMLVSSMFPRIISAHFPGAVYVSQSLHFRSPVYIGDEILGLVQAIALRETKNKYIVKFSTKCFKNHNELVVIDGEATAILPNLDMLQKSPSE", "length": 166 }, "evidence": [ { "id": "A0A8V0ZG22", "url": "https://omabrowser.org/oma/group/A0A8V0ZG22/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22" } ], "pmid": "" }, { "name": "ribonuclease P complex", "id": "GO:0030677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "3-hydroxyacyl-CoA dehydratase activity", "id": "GO:0018812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018812", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22" } ], "pmid": "" }, { "name": "(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity", "id": "GO:0019171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZG22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG22" }, { "id": "PF01575", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01575" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MaoC-like", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 145, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFW0-1", "uniprot_ac": "A0A8V0ZFW0", "uniprot_id": "A0A8V0ZFW0_CHICK", "mass": { "chemical_mass": 107951.0, "monoisotopic_mass": 107951.0 }, "refseq": {}, "gene_names": [ { "name": "TXNDC11", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW0" } ] } ], "protein_names": [ { "name": "Thioredoxin domain containing 11", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TXNDC11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW0", "locus": { "chromosome": "14", "start_pos": 922335, "end_pos": 899763, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020760", "url": "https://www.ensembl.org/id/ENSGALG00010020760" } ] } } ], "crossref": [ { "id": "A0A8V0ZFW0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFW0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003154", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003154", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02995", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02995", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03006", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03006", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416428", "url": "https://www.ncbi.nlm.nih.gov/gene/416428", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052792", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052792", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VIYLYHQ", "url": "https://omabrowser.org/oma/group/VIYLYHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFW0", "url": "https://www.orthodb.org/?gene=A0A8V0ZFW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C358", "url": "https://www.orthodb.org/?gene=E1C358", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46497", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46497", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46497:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46497:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-209968", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-209968", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZFW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C358", "url": "https://www.uniprot.org/uniprotkb/E1C358", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C358-1", "url": "https://www.uniprot.org/uniprotkb/E1C358-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLCGGPGPGPASASRLRPRAAQMARRPELLCGAAIVLGCAFLVALKVTCSRAKDVTMPAKLPVNFFSTRSPVIDLFRGQLDYADHLRQDSEIVLYFFYAPWCGQSVAVREEIEHVANRLSDQVLFVAINCWWNQGKCRKQKHFFYFPVIHLYHRSFGPIEYKGPMSAVYIEKFVRRVMTPLLYISSRSKLLDFLSNYECKAEIIKASFEIPKEGIQLGRYLPHPGWSPGVVGYFEFNASPQPPGYLTFFSSALHSLKKDYLGTIRFGVITDKHVAEEISLVHPGSVYLHRHINTSLIYPNGIMNYTAENVCKWALENRELLIRWLRPHGGKSLLLNNELKKGPALLVFIPYNPLTEIQPLLDEITKVALEYHSCNKSQAAEPELQHLGNSDSPASDSSDPDAHMKSAETFLITKYPCCNTVVLPQWHSISRTHNVCELCINQTLGVKPDKVNVPHCNFFEIETALDSFYLQEHTFFQVVSNSIECSNFLSFYSPFSYYTACCRTVDRHFLSFISSEKTIFQTPKVAFSSHGKKDNADVQNSIPHIEDRNCFIPDLHISGTNITGLSCRTNKTLNLYLLDSNLFWIYAERLGASRSTHLKEFAAIVDLKEELHYVLDQNQSLTGSTLENFIKNFSILYSPLKRHLVDGSSVRVPAERVVVEVTTSTFHHVVFSSEKNVLLLYYAQWCGFCASLNHIFIQLARLLPPDHFTVARIDITENDLPWEFMTDRLPTILFFPHRRKDQSVKFPEDFPVSLPHLLKFILHHSSLSSSEPCTKECLHKETVLQQGHISHLEKEIQKLRSEIRALHRAHESLEAQLSKARREEHRLQQQKHTLEKQHKTLQLHSQQLQATYDQKNRELLEMAEKLQELADASENLLKENTLLRILVASRDGKLQSKDESKEALQSEQTVADDSSVLVSTALTTEEKRIDHVDTVATEHSSENRTE", "length": 947, "header": "tr|A0A8V0ZFW0-1|A0A8V0ZFW0_CHICK Isoform 1 of Thioredoxin domain containing 11 OS=Gallus gallus OX=9031 GN=TXNDC11 PE=4 SV=1 CANONICAL=A0A8V0ZFW0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW0/entry#A0A8V0ZFW0-1", "sequence": { "sequence": "MSLCGGPGPGPASASRLRPRAAQMARRPELLCGAAIVLGCAFLVALKVTCSRAKDVTMPAKLPVNFFSTRSPVIDLFRGQLDYADHLRQDSEIVLYFFYAPWCGQSVAVREEIEHVANRLSDQVLFVAINCWWNQGKCRKQKHFFYFPVIHLYHRSFGPIEYKGPMSAVYIEKFVRRVMTPLLYISSRSKLLDFLSNYECKAEIIKASFEIPKEGIQLGRYLPHPGWSPGVVGYFEFNASPQPPGYLTFFSSALHSLKKDYLGTIRFGVITDKHVAEEISLVHPGSVYLHRHINTSLIYPNGIMNYTAENVCKWALENRELLIRWLRPHGGKSLLLNNELKKGPALLVFIPYNPLTEIQPLLDEITKVALEYHSCNKSQAAEPELQHLGNSDSPASDSSDPDAHMKSAETFLITKYPCCNTVVLPQWHSISRTHNVCELCINQTLGVKPDKVNVPHCNFFEIETALDSFYLQEHTFFQVVSNSIECSNFLSFYSPFSYYTACCRTVDRHFLSFISSEKTIFQTPKVAFSSHGKKDNADVQNSIPHIEDRNCFIPDLHISGTNITGLSCRTNKTLNLYLLDSNLFWIYAERLGASRSTHLKEFAAIVDLKEELHYVLDQNQSLTGSTLENFIKNFSILYSPLKRHLVDGSSVRVPAERVVVEVTTSTFHHVVFSSEKNVLLLYYAQWCGFCASLNHIFIQLARLLPPDHFTVARIDITENDLPWEFMTDRLPTILFFPHRRKDQSVKFPEDFPVSLPHLLKFILHHSSLSSSEPCTKECLHKETVLQQGHISHLEKEIQKLRSEIRALHRAHESLEAQLSKARREEHRLQQQKHTLEKQHKTLQLHSQQLQATYDQKNRELLEMAEKLQELADASENLLKENTLLRILVASRDGKLQSKDESKEALQSEQTVADDSSVLVSTALTTEEKRIDHVDTVATEHSSENRTE", "length": 947, "header": "tr|A0A8V0ZFW0-1|A0A8V0ZFW0_CHICK Isoform 1 of Thioredoxin domain containing 11 OS=Gallus gallus OX=9031 GN=TXNDC11 PE=4 SV=1 CANONICAL=A0A8V0ZFW0-1" }, "locus": { "chromosome": "14", "start_pos": 920028, "end_pos": 899828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050188.1", "url": "https://www.ensembl.org/id/ENSGALT00010050188.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029653.1", "url": "https://www.ensembl.org/id/ENSGALP00010029653.1" } ] } }, { "isoform_ac": "E1C358-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW0/entry#E1C358-1", "sequence": { "sequence": "MSLCGGPGPGPASASRLRPRAAQMARRPELLCGAAIVLGCAFLVALKVTCSRAKDVTMPAKLPVNFFSTRSPVIDLFRGQLDYADHLRQDSEIVLYFFYAPWCGQSVAVREEIEHVANRLSDQVLFVAINCWWNQGKCRKQKHFFYFPVIHLYHRSFGPIEYKGPMSAVYIEKFVRRVMTPLLYISSRSKLLDFLSNYEPGVVGYFEFNASPQPPGYLTFFSSALHSLKKDYLGTIRFGVITDKHVAEEISLVHPGSVYLHRHINTSLIYPNGIMNYTAENVCKWALENRELLIRWLRPHGGKSLLLNNELKKGPALLVFIPYNPLTEIQPLLDEITKVALEYHSCNKSQAAEPELQHLGNSDSPASDSSDPDAHMKSAETFLITKYPCCNTVVLPQWHSISRTHNVCELCINQTLGVKPDKVNVPHCNFFEIETALDSFYLQEHTFFQVVSNSIECSNFLSFYSPFSYYTACCRTVDRHFLSFISSEKTIFQTPKVAFSSHGKKDNADVQNSIPHIEDRNCFIPDLHISGTNITGLSCRTNKTLNLYLLDSNLFWIYAERLGASRSTHLKEFAAIVDLKEELHYVLDQNQSLTGSTLENFIKNFSILYSPLKRHLVDGSSVRVPAERVVVEVTTSTFHHVVFSSEKNVLLLYYAQWCGFCASLNHIFIQLARLLPPDHFTVARIDITENDLPWEFMTDRLPTILFFPHRRKDQSVKFPEDFPVSLPHLLKFILHHSSLSSSEPCTKECLHKETVLQQGHISHLEKEIQKLRSEIRALHRAHESLEAQLSKARREEHRLQQQKHTLEKQHKTLQLHSQQLQATYDQKNRELLEMAEKLQELADASENLLKENTLLRILVASRDGKLQSKDESKEALQSEQTVADDSSVLVSTALTTEEKRIDHVDTVATEHSSENRTE", "length": 918, "header": "tr|E1C358-1|A0A8V0ZFW0_CHICK Computationally mapped isoform of Thioredoxin domain containing 11 OS=Gallus gallus OX=9031 GN=TXNDC11 PE=4 SV=1 CANONICAL=A0A8V0ZFW0-1" }, "locus": { "chromosome": "14", "start_pos": 920028, "end_pos": 899828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050194.1", "url": "https://www.ensembl.org/id/ENSGALT00010050194.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029656.1", "url": "https://www.ensembl.org/id/ENSGALP00010029656.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-209968", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-209968", "resource": "Reactome", "description": "Thyroxine biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IQE1-1", "protein_name": "Thioredoxin domain-containing protein 11", "gene_name": "txndc11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRRVRAELRQAVNQMARRPVKILCCGAVLLTCALLLPITLTCGRVKSVVSPARPPMRFFPAEAPVLDLFLGQLEEADRLREEADVSVLFFYAPWCAHSITARQHVQQVALRLADQVQFLAVNCWWHQGRCRKQKSFFQYPVIHLYYRRFGPIEYRGPVRSDYLESFILRVCAPLVYLPTAGALHSFLTQHQQGVVGYFRFSWSPQPAGYLTFLLSALHALRRDHQGAVRFAVVTNQAVAEGVSLREDESVYLHRRLNSSLVFPRAQRNFTAQAVSDWVLENKESVVYWIQPTRAKSYSLEAELQKGPALLTFLPHNPLTANQLLDQVSAVALLYQSGCGSSAPRLCCQCVPVCASSGVCEVCVQRSVCSGLHQSLQRLQSSASCWSVQSSYTPSGRLSVCCGASVCRGGASVCSGASISGLQCRSNRTLRFYMLDAELHRPLAHRLGARGGLHRPFITIINLRDETHHVLEPSGTLEGFIQNFSVPYSPLRRHLVGQEAPQQTQSLVQEVTSDSFLQTVMDSQRDVLLLYYSAWCGFCSVLNHVFLQLGRLFRGNRALTVARVNVGRNDLPWEFMVDHLPTVLFFPRHRKQMSVKFPENTPMTVPNLLRFVLQHTGHAPWEEQQSGEGEEPVRGEESVSLLGAELRALQQEVFSLHRVRERVSQQLDVLWRENRRLTLHTHTLQSQNQELQAQIHQLEALYREKTHQLTHTVHRLQELADASEELLKENTLLKVLLTALSDADHRQTTEDRQTTDHRQATEEHDENTHAEDESS", "length": 775 }, "evidence": [ { "id": "A0A8V0ZFW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZFW0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1N1E5-1", "protein_name": "Thioredoxin domain containing 11", "gene_name": "TXNDC11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSECGGRGGGGGSSSSSDDAEDEGGGGGPAGSGSLSPAPAASSEGRLRRGLRGASLMARRRPELLCGAVALGCALLLALKFTCSRAKDVIIPAKPPVSFFSSRSPVLDLFQGQLDYAEHIRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFYFPVIYLYHRSFGPIEYKGPMSAVYIEKFVRRVMKPLLYIPSQSELLDFLSNYEPGVLGYFEFSGSPQPPGYLTFFTSALHSLKKDYLGTVRFGVITNKHLAKLVSLVHSGSVYLHRHFNTSLVFPREVINYTAENICKWALENRETLVRWLWPHGGKSLLLNNELKKGPALFVFIPFNPLAESHPLIDEITEVALEYNNCHGDQVVERLLQHLRRVDAPAFKSLAPDPPARLPDPPLITASPCCNTVVLPRWHSISRTHNVCELCVNQTAGGLRPSSVSMPQCSFFEMAAALDSFYLKEQTFYHVVSDSIECSNFLSFYSPFSYYTACCRTINRGVAGFIDSEQGVFETPPVAFSSLEKKCEVESPGSVPHIEENRYLFPELETSSSSFTGLSCRTNKTLNIYLLDSNLFWLYAERLGAPSAARVKEFATIVDVKEESHYILDPKQALMKFTLESFIQNFSVLYSPLKRHLIGSDSTQFTSQRLITEVTTDTFWEVVLQKQDVLLLYYAQWCGFCPALNHVFIQLARLLPSDTFTVARIDVSQNDLPWEFMVDRLPTVLFFPCNRKDLSVKYPEDLPITLPNLLRFILHHSDPASDPRNLAGPPTAECLQNEAVLQQGHIAHLEREIRKLRAEIGTLQRAQVQVEARLASARRDEHRLLRQQHTLERQHDLLRLHSEQLQALYEHKTRELDEVARKLQELADASETLLTENTWLKILVATMEQKLEGRDGADDRVPPSKARSEHPEPPGAPRLPASTPLPANISSTLASEGSPENRTD", "length": 957 }, "evidence": [ { "id": "A0A8V0ZFW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZFW0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RL25-1", "protein_name": "Thioredoxin domain containing 11", "gene_name": "TXNDC11", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSECGGRGSGSSSSDDAADEGGGGGGPAGSGFLSPAPASSSEGRLRRGLHGASLMARRRPELLCGAVALGCALLLALKFTCSRAKDVIIPAKPPVSFFSSRSPVLDLFQGQLDYAEHVRRDSEVVLLFFYAPWCGQSIAARAEIEQAARQLSDQVLFVAINCWWNQGKCRKQKHFFYFPVIYLYHRSFGPIEYKGPMSAVYIEKFVRRVMKPLLYIPSQSELLDFLSNYEPGVLGYFEFNGSPQPPGYLTFFTSALHSLKKDYLGTVRFGVITNKHLAKLVSLAHSGSVYLHRHFNTSLVFPREVINYTAENVYKWALENRETLLRWLRPHGGKSLLLQNELKKGPALFLFIPFNPLAESHPLIDEITEVALEYNNCHGDQVVERLLQHLRRVDAPVFKSLAPEPPARLLDPPLGSASPCCNTVVLPQWHSISRTHNVCELCVNQTAGGVRPSSVSVPQCSFFDMAAALDSFYLKEQTFYHVASDSIECSNFLSFYSPFSYYSACCRTISRGGTGLIDSEQDAFESPTTAFSSLEKKCEVDPPSSVPHIEENRYLFPELDVTSTSFTGLSCRTNKTLNMYLLDSNLFWLYAERLGAPSTAQVKEFATIVDVKEESHYILDPKLALMKFTLESFIQNFSALYSPLKRHLIGSDSAQFSSQRFITEVTTDSFWEVVLQKQDVLLLYYAQWCGFCPSLNHIFIQLARLLPADTFTVARIDVSQNDLPWEFMVDRLPTVLFFPCNRKDLSVKYPEDLPITLPNLLRFILHHSNPASSAPRNPAHPPTKECLQSEAVLQQGHISHLEREIQKLRAEIGALQRAQAQVEARLASARRDEHRLRQQQQALERQHGLLRLHSQQLQSLYEHKTRELEEVARKLQELADASENLLTENTWLKILVATMERKLEGRDRPQDRAPSAHPEPAGTPRLPAGTPPPSNVSATLASERSQENRTD", "length": 951 }, "evidence": [ { "id": "A0A8V0ZFW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZFW0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6PKC3-1", "protein_name": "Thioredoxin domain-containing protein 11", "gene_name": "TXNDC11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSECGGRGGGSSSSEDAEDEGGGGGGPAGSDCLSSSPTLATASSAGRLRRGLRGAFLMARQRPELLCGAVALGCALLLALKFTCSRAKDVIIPAKPPVSFFSLRSPVLDLFQGQLDYAEYVRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSDQVLFVAINCWWNQGKCRKQKHFFYFPVIYLYHRSFGPIEYKGPMSAVYIEKFVRRVMKPLLYIPSQSELLDFLSNYEPGVLGYFEFSGSPQPPGYLTFFTSALHSLKKALESTSSPRALVSFTGEWHLETKIYVLDYLGTVRFGVITNKHLAKLVSLVHSGSVYLHRHFNTSLVFPREVLNYTAENICKWALENQETLFRWLRPHGGKSLLLNNELKKGPALFLFIPFNPLAESHPLIDEITEVALEYNNCHGDQVVERLLQHLRRVDAPVLESLALEVPAQLPDPPTITASPCCNTVVLPQWHSFSRTHNVCELCVNQTSGGMKPSSVSVPQCSFFEMAAALDSFYLKEQTFYHVASDSIECSNFLTSYSPFSYYTACCRTISRGVSGFIDSEQGVFEAPTVAFSSLEKKCEVDAPSSVPHIEENRYLFPEVDMTSTNFTGLSCRTNKTLNIYLLDSNLFWLYAERLGAPSSTQVKEFAAIVDVKEESHYILDPKQALMKLTLESFIQNFSVLYSPLKRHLIGSGSAQFPSQHLITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQLARNLPMDTFTVARIDVSQNDLPWEFMVDRLPTVLFFPCNRKDLSVKYPEDVPITLPNLLRFILHHSDPASSPQNVANSPTKECLQSEAVLQRGHISHLEREIQKLRAEISSLQRAQVQVESQLSSARRDEHRLRQQQRALEEQHSLLHAHSEQLQALYEQKTRELQELARKLQELADASENLLTENTWLKILVATMERKLEGRDGAESLAAQREVHPKQPEPSATPQLPGSSPPPANVSATLVSERNKENRTD", "length": 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"A0A8V0ZFW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZFW0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { 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{ "uniprot_canonical_ac": "A0A8V0ZH76-1", "uniprot_ac": "A0A8V0ZH76", "uniprot_id": "A0A8V0ZH76_CHICK", "mass": { "chemical_mass": 25563.0, "monoisotopic_mass": 25563.0 }, "refseq": {}, "gene_names": [ { "name": "RNF141", "type": "recommended", "evidence": [ { "id": "A0A8V0ZH76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH76" } ] } ], "protein_names": [ { "name": "RING finger protein 141", "type": "recommended", "evidence": [ { "id": "A0A8V0ZH76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH76/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH76" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF141", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH76", "locus": { "chromosome": "5", "start_pos": 8615852, "end_pos": 8575186, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021070", "url": "https://www.ensembl.org/id/ENSGALG00010021070" } ] } } ], "crossref": [ { "id": "A0A8V0ZH76", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZH76", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16545", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16545", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFX2", "url": "https://www.orthodb.org/?gene=A0A8V0ZFX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH76", "url": "https://www.orthodb.org/?gene=A0A8V0ZH76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12109:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12109:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZFX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQQISSQTQTVMNKLPEKVAKHASLVQESGFLTYEEFLGRVAELNDVTAKLASGQEKHLLFEVQPGSDSSAFWKVVVRIILFLKINKTSGIVEASRILNLYQFVQLYKDITSQAAGVLAQSETSEEAAESLTSVSSSQASLWMGRLKQPTDEDECCICMDGRVDLILPCAHSFCQKCIDKWSDRHRSCPVCRRQVTGAGDSWVVSDAPTEDDIATYILNMVDEVGQPLRP", "length": 231, "header": "tr|A0A8V0ZH76-1|A0A8V0ZH76_CHICK Isoform 1 of RING finger protein 141 OS=Gallus gallus OX=9031 GN=RNF141 PE=4 SV=1 CANONICAL=A0A8V0ZH76-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH76/entry#A0A8V0ZFX2-1", "sequence": { "sequence": "MGQQISSQTQTVMNKLPEKVAKHASLVQESGFLTYEEFLGRVAELNDVTAKLASGQEKHLLFEVQPGSDSSAFWKVVVRIICTKINKTSGIVEASRILNLYQFVQLYKDITSQAAGVLAQSETSEEAAESLTSVSSSQASLWMGRLKQPTDEDECCICMDGRVDLILPCAHSFCQKCIDKWSDRHRSCPVCRRQVTGAVTRFVILGSQMRNSVTDEEIENVRTSHVTEAPRET", "length": 233, "header": "tr|A0A8V0ZFX2-1|A0A8V0ZH76_CHICK Computationally mapped isoform of RING finger protein 141 OS=Gallus gallus OX=9031 GN=RNF141 PE=4 SV=1 CANONICAL=A0A8V0ZH76-1" }, "locus": { "chromosome": "5", "start_pos": 8613580, "end_pos": 8576315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050986.1", "url": "https://www.ensembl.org/id/ENSGALT00010050986.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030177.1", "url": "https://www.ensembl.org/id/ENSGALP00010030177.1" } ] } }, { "isoform_ac": "A0A8V0ZH76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH76/entry#A0A8V0ZH76-1", "sequence": { "sequence": "MGQQISSQTQTVMNKLPEKVAKHASLVQESGFLTYEEFLGRVAELNDVTAKLASGQEKHLLFEVQPGSDSSAFWKVVVRIILFLKINKTSGIVEASRILNLYQFVQLYKDITSQAAGVLAQSETSEEAAESLTSVSSSQASLWMGRLKQPTDEDECCICMDGRVDLILPCAHSFCQKCIDKWSDRHRSCPVCRRQVTGAGDSWVVSDAPTEDDIATYILNMVDEVGQPLRP", "length": 231, "header": "tr|A0A8V0ZH76-1|A0A8V0ZH76_CHICK Isoform 1 of RING finger protein 141 OS=Gallus gallus OX=9031 GN=RNF141 PE=4 SV=1 CANONICAL=A0A8V0ZH76-1" }, "locus": { "chromosome": "5", "start_pos": 8583834, "end_pos": 8576315, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050983.1", "url": "https://www.ensembl.org/id/ENSGALT00010050983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030174.1", "url": "https://www.ensembl.org/id/ENSGALP00010030174.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH76" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH76" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH76" } ], "pmid": "" } ] } ] }, 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"length": 1097, "header": "tr|A0A8V0ZFY0-1|A0A8V0ZFY0_CHICK Isoform 1 of von Willebrand factor A domain containing 5B1 OS=Gallus gallus OX=9031 GN=VWA5B1 PE=4 SV=1 CANONICAL=A0A8V0ZFY0-1" }, "locus": { "chromosome": "21", "start_pos": 4872335, "end_pos": 4856548, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050360.1", "url": "https://www.ensembl.org/id/ENSGALT00010050360.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029744.1", "url": "https://www.ensembl.org/id/ENSGALP00010029744.1" } ] } }, { "isoform_ac": "A0A8V0ZG37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY0/entry#A0A8V0ZG37-1", "sequence": { "sequence": "MPGLINQSSHCPLLLTASEVTSCVSGYALGMTASLTYRNLQAQPCKVGVCHVPWRQGDSCPCGIHQNGDAESCGLGSLERRAGVALGSLGSSVLCGCGTLIWLSLSAGRIVMDEDLERIAFVANLGTIPPLESVSIFISTSSELQTLPSGAVRVLLPAVCVPMVPQPIRVQLPPGDPRAVLAGRYGAACDAHTHHPPFLPLRGVLWPSLTTPWSLHAGVESPTHEIRADADPSARSAKSIVITLANRHTFDRPVEILIHPSEPHMPHILMEEGDMTPAEYEQHLKGKNDFIKGTKKDPSTEIIRKRLHKDIPHHPVLMLNFCPELSTAPADLQKAAGEFIFLVDCSGSSTSIGRAKDALLVALKSLTPACLFNIVTFSSTFKILFPASRTYCESLAVACESIRRMHADTGSPNILSPLKWIVRQPIRRGHPRLLFLLSHGAISNAGTVLELLRNHSCSTRYGAQSWGAAAHSRARVRSTEPQRSLKKAMAPVLSDVSVEWVFPESTEALVSPLSSSCLFPGDRLVGYSIICDTSLYISKPRAVSATLLPLSFPAWLRSPWHRCAKPNAGTALLSPGQEAAVQHHALPGVGQLRFLSFPRRGDMERTPGATLEVCPSWGVKLNVFAFPSPSLPPHASPQPGSAVRVPVGPPCCSRAMCPPATAPRPHQHLTWLWGGLRGCSMPACSPHPTAGALGSRVMWERDLGGVTSSDWEPQDWDSGATRGSPRSPRASCKAVVKGLQGGEPMQWEITFDLPALLRERDGQEEDVWSETFHQLAARAVIRDLELLAERERDIEHGNGASASRPGRRYQLNAIHTSKACNVISKYTAFVPVELSSGTYLPPIIEYSHTRLLTRAAKSFMSKSPGRASDASSESDSESTHYLPLVSSSALGREPLGLPALCREVHWGMGISSFPARGACGWYLRAPRCSLQVSLQLACGAFLMNSAFCEAVSIPMEKLRWTSPFSCHRLALSPSGSSSMKKPEQRGSSSTLAEHADVQTLLLDIELQKQTEPEGMLWATAVALAWLEHSSASHFTEWELVAAKASLWLGEQGFPQGCSLAAVKSAAQQLFVLLRHWDENLEFNLLCYNPGTV", "length": 1092, "header": "tr|A0A8V0ZG37-1|A0A8V0ZG37_CHICK Computationally mapped isoform of von Willebrand factor A domain containing 5B1 OS=Gallus gallus OX=9031 GN=VWA5B1 PE=4 SV=1 CANONICAL=A0A8V0ZFY0-1" }, "locus": { "chromosome": "21", "start_pos": 4872335, "end_pos": 4856548, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050358.1", "url": "https://www.ensembl.org/id/ENSGALT00010050358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029743.1", "url": "https://www.ensembl.org/id/ENSGALP00010029743.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 694, "start_aa": "Thr", "end_pos": 694, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr694", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZFY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY0" }, { "id": "PS51468", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51468" } ], "ann_type": "Domain_Extent_Annotation", 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] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "all-trans-retinol dehydrogenase (NADP+) activity", "id": "GO:0052650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ2" } ], "pmid": "" }, { "name": "all-trans-retinol dehydrogenase (NAD+) activity", "id": "GO:0004745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004745", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "retinoid metabolic process", "id": "GO:0001523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ2" } ], "pmid": "" }, { "name": "regulation of retinoic acid receptor signaling pathway", "id": 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The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, photoreceptor outer segment membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZFZ2-1" ], "evidence": [ { "id": "R-GGA-2465940", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2465940" } ] }, { "id": "R-GGA-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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The reference sequence was derived from JAENSK010000214.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376573", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376573" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C11orf94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ5", "locus": { "chromosome": "5", "start_pos": 23459619, "end_pos": 23458967, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022000", "url": "https://www.ensembl.org/id/ENSGALG00010022000" } ] } } ], "crossref": [ { "id": "A0A8V0ZFZ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFZ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100859336", "url": "https://www.ncbi.nlm.nih.gov/gene/100859336", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IRPKHPW", "url": "https://omabrowser.org/oma/group/IRPKHPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFZ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZFZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37872:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37872:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15878", "url": 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This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149716" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "METTL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ6", "locus": { "chromosome": "14", "start_pos": 8761424, "end_pos": 8742437, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019043", "url": "https://www.ensembl.org/id/ENSGALG00010019043" } ] } } ], "crossref": [ { "id": "A0A8V0ZFZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFZ6", "database": 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"id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-L-histidine N-pros-methyltransferase activity", "id": "GO:0106370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106370", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZFZ7-1", "uniprot_ac": "A0A8V0ZFZ7", "uniprot_id": "A0A8V0ZFZ7_CHICK", "mass": { "chemical_mass": 132506.0, "monoisotopic_mass": 132506.0 }, "refseq": { "ac": "XP_004942166", "name": "protein transport protein Sec31B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942166" }, "gene_names": [ { "name": "SEC31B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ] }, { "name": "SEC31B", "type": "synonym", "evidence": [ { "id": "XP_004942166", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942166" } ] } ], "protein_names": [ { "name": "Protein transport protein Sec31A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7/entry#names_and_taxonomy" } ] }, { "name": "SEC31-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7/entry#names_and_taxonomy" } ] }, { "name": "SEC31-related protein A", "type": "synonym", "evidence": [ { "id": "A0A8V0ZFZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7/entry#names_and_taxonomy" } ] }, { "name": "protein transport protein Sec31B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004942166", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942166" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004942166.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942166", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942166" } ] }, { "annotation": "Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7#function" }, { "database": "UniProtKB", "id": "ARBA00025471", "url": "https://www.uniprot.org/uniprotkb/ARBA00025471#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHA7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEC31B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7", "locus": { "chromosome": "6", "start_pos": 18215082, "end_pos": 18183294, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021077", "url": "https://www.ensembl.org/id/ENSGALG00010021077" } ] } } ], "crossref": [ { "id": "A0A8V0ZFZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZFZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "423764", "url": "https://www.ncbi.nlm.nih.gov/gene/423764", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423764", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423764", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AQWAFGG", "url": "https://omabrowser.org/oma/group/AQWAFGG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFZ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZFZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHA7", "url": "https://www.orthodb.org/?gene=A0A8V0ZHA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13923", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13923", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13923:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13923:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004942166", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942166", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLKEIERTAVEVWSPANNHPIYLATGTSAQQLDASFSTNATLEIFEVDFRDPSLDMKQKGTLPASNRFHKLIWGNFGNGSPESSGVIIGGGDNGVLTMYSAHRILASKSDPVIGQTEKHSGPVRALDFNPFQSNLLASGANDSEIFIWDLNNFSVPMTPGTKSQPHEDISVVSWNRQVQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGMAWHPEVATQLVLSSEDDRLPVIQIWDLRFATSPLSQLEGHTRGVLSVSWCQADPELLLSSAKDNRILCWNPSTGEVVYELPIRSQWCFDVQWCPRNPSVFSAATFDGWINIYSVMGGNLEAQQKTQADKISSSFNNLDPFGTGQTLPPLQVPEQVAQTTLIPPLKKPPKWIRRPVGVSFAFGGKLITFGLTKAPGQQTQQTYPHQVFISQVTTETEFLLRSRELQMALQSGNLLDYCKGKIQTAKLKYEENLWKFLKVNLEQESRTKLLKLLGYSKEDLQKKITSCLSNGIPDKQTLPEADDTNTAQPDQLLINSSDDVAAVSSSSAFFDNLIPQNMSTLEIPVTEDTDGLISQALLLGNFEGAVELCMRAERFADAIILAIAGGENLLKETQKRYFAKRKTKLSLLLSSIVQQKWQDIVCTCDLQSWKEALAILLTYSKHEDYTQLCDMLGSRLELEGDASLSNDACLCYISSGNVERLVECWVKNHETSSPLALQDLIEKVMVLSRSIEMLRGTAEPAPGPVLAEQITQYASLLASQGCLAAAMNYLPNSSKELLIEQLRDRLFHAQGENVGDQPPPPFPYTRVNVGVTKHASPAAQRGSTPEGAAHKTDGRHPEKPNYQSSFAPSAPSQPSVPSFFPPQPVPAMSAAPHHVVPPQTSSSPQTSIYSRGLPYPQYNVGMVPATASGPALSQSQPFSPVGARPVGPAPFPSQPPLSGQSMPMTSPGVLPSGPALFAPASIPASQPPAACPLPVAAPLGFSSAPFSSPMNVGYPQGGPGAPSTKPLPAASLPPPPIGFFPWLDPHVDHAAQESWTDPSTARGSLQKKKLPEKFAPLAPITAPVMSLPTEPQGIHPQLSRLQESGQSPPGAPKEGSLQYHQLPAEKVEKKEVPPEHQGLKTTLEGLVQRCSAVATDPKTRRKLEDALQRLETLYDKLREQALSPAILMGLHEIARCIEARNYQQGLMVHTQVVSSSSFSEVSGFMPVLKVLMTIAGKLNV", "length": 1217, "header": "tr|A0A8V0ZFZ7-1|A0A8V0ZFZ7_CHICK Isoform 1 of Protein transport protein Sec31A OS=Gallus gallus OX=9031 GN=SEC31B PE=1 SV=1 CANONICAL=A0A8V0ZFZ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7/entry#A0A8V0ZFZ7-1", "sequence": { "sequence": "MKLKEIERTAVEVWSPANNHPIYLATGTSAQQLDASFSTNATLEIFEVDFRDPSLDMKQKGTLPASNRFHKLIWGNFGNGSPESSGVIIGGGDNGVLTMYSAHRILASKSDPVIGQTEKHSGPVRALDFNPFQSNLLASGANDSEIFIWDLNNFSVPMTPGTKSQPHEDISVVSWNRQVQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGMAWHPEVATQLVLSSEDDRLPVIQIWDLRFATSPLSQLEGHTRGVLSVSWCQADPELLLSSAKDNRILCWNPSTGEVVYELPIRSQWCFDVQWCPRNPSVFSAATFDGWINIYSVMGGNLEAQQKTQADKISSSFNNLDPFGTGQTLPPLQVPEQVAQTTLIPPLKKPPKWIRRPVGVSFAFGGKLITFGLTKAPGQQTQQTYPHQVFISQVTTETEFLLRSRELQMALQSGNLLDYCKGKIQTAKLKYEENLWKFLKVNLEQESRTKLLKLLGYSKEDLQKKITSCLSNGIPDKQTLPEADDTNTAQPDQLLINSSDDVAAVSSSSAFFDNLIPQNMSTLEIPVTEDTDGLISQALLLGNFEGAVELCMRAERFADAIILAIAGGENLLKETQKRYFAKRKTKLSLLLSSIVQQKWQDIVCTCDLQSWKEALAILLTYSKHEDYTQLCDMLGSRLELEGDASLSNDACLCYISSGNVERLVECWVKNHETSSPLALQDLIEKVMVLSRSIEMLRGTAEPAPGPVLAEQITQYASLLASQGCLAAAMNYLPNSSKELLIEQLRDRLFHAQGENVGDQPPPPFPYTRVNVGVTKHASPAAQRGSTPEGAAHKTDGRHPEKPNYQSSFAPSAPSQPSVPSFFPPQPVPAMSAAPHHVVPPQTSSSPQTSIYSRGLPYPQYNVGMVPATASGPALSQSQPFSPVGARPVGPAPFPSQPPLSGQSMPMTSPGVLPSGPALFAPASIPASQPPAACPLPVAAPLGFSSAPFSSPMNVGYPQGGPGAPSTKPLPAASLPPPPIGFFPWLDPHVDHAAQESWTDPSTARGSLQKKKLPEKFAPLAPITAPVMSLPTEPQGIHPQLSRLQESGQSPPGAPKEGSLQYHQLPAEKVEKKEVPPEHQGLKTTLEGLVQRCSAVATDPKTRRKLEDALQRLETLYDKLREQALSPAILMGLHEIARCIEARNYQQGLMVHTQVVSSSSFSEVSGFMPVLKVLMTIAGKLNV", "length": 1217, "header": "tr|A0A8V0ZFZ7-1|A0A8V0ZFZ7_CHICK Isoform 1 of Protein transport protein Sec31A OS=Gallus gallus OX=9031 GN=SEC31B PE=1 SV=1 CANONICAL=A0A8V0ZFZ7-1" }, "locus": { "chromosome": "6", "start_pos": 18213469, "end_pos": 18187128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051011.1", "url": "https://www.ensembl.org/id/ENSGALT00010051011.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030202.1", "url": "https://www.ensembl.org/id/ENSGALP00010030202.1" } ] } }, { "isoform_ac": "A0A8V0ZHA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7/entry#A0A8V0ZHA7-1", "sequence": { "sequence": "MKLKEIERTAVEVWSPANNHPIYLATGTSAQQLDASFSTNATLEIFEVDFRDPSLDMKQKGTLPASNRFHKLIWGNFGNGSPESSGVIIGGGDNGVLTMYSAHRILASKSDPVIGQTEKHSGPVRALDFNPFQSNLLASGANDSEIFIWDLNNFSVPMTPGTKSQPHEDISVVSWNRQVQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGMAWHPEVATQLVLSSEDDRLPVIQIWDLRFATSPLSQLEGHTRGVLSVSWCQADPELLLSSAKDNRILCWNPSTGEVVYELPIRSQWCFDVQWCPRNPSVFSAATFDGWINIYSVMGGNLEAQQKTQADKISSSFNNLDPFGTGQTLPPLQVPEQVAQTTLIPPLKKPPKWIRRPVGVSFAFGGKLITFGLTKAPGQQTQQTYPHQVFISQVTTETEFLLRSRELQMALQSGNLLDYCKGKIQTAKLKYEENLWKFLKVNLEQESRTKLLKLLGYSKEDLQKKITSCLSNGIPDKQTLPEADDTNTAQPDQLLINSSDDVAAVSSSSAFFDNLIPQNMSTLEIPVTEDTDGLISQALLLGNFEGAVELCMRAERFADAIILAIAGGENLLKETQKRYFAKRKTKLSLLLSSIVQQKWQDIVCTCDLQSWKEALAILLTYSKHEDYTQLCDMLGSRLELEGDASLSNDACLCYISSGNVERLVECWVKNHETSSPLALQDLIEKVMVLSRSIEMLRGTAEPAPGPVLAEQITQYASLLASQGCLAAAMNYLPNSSKELLIEQLRDRLFHAQGENVGDQPPPPFPYTRVNVGVTKHASPAAQRGSTPEGAAHKTDGRHPEKPNYQSSFAPSAPSQPSVPSFFPPQPVPAMSAAPHHVVPPQTSSSPQTSIYSRGLPYPQYNVGMVPATASGPALSQSQPFSPVGARPVGPAPFPSQPPLSGQSMPMTSPGVLPSGPALFAPASIPASQPPAACPLPVAAPLGFSSAPFSSPMNVGYPQGGPGAPSTKPLPAASLPPPPIAQESWTDPSTARGSLQKKKLPEKFAPLAPITAPVMSLPTEPQGIHPQLSRLQESGQSPPGAPKEGSLQYHQLPAEKVEKKEVPPEHQGLKTTLEGLVQRCSAVATDPKTRRKLEDALQRLETLYDKLREQALSPAILMGLHEIARCIEARNYQQGLMVHTQVVSSSSFSEVSGFMPVLKVLMTIAGKLNV", "length": 1204, "header": "tr|A0A8V0ZHA7-1|A0A8V0ZHA7_CHICK Computationally mapped isoform of Protein transport protein Sec31A OS=Gallus gallus OX=9031 GN=SEC31B PE=1 SV=1 CANONICAL=A0A8V0ZFZ7-1" }, "locus": { "chromosome": "6", "start_pos": 18213469, "end_pos": 18187128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051013.1", "url": "https://www.ensembl.org/id/ENSGALT00010051013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030204.1", "url": "https://www.ensembl.org/id/ENSGALP00010030204.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423764", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423764", "resource": "KEGG Pathway" }, { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L020-1", "protein_name": "Protein transport protein Sec31B", "gene_name": "Sec31b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLKELEKPAVQAWSPAKQYPVYLATGTSAQQLDASFSTNATLEIFEVDFRDPSLDLKRKGILSVSSRFHKLIWGSSSSGLLENTGVIAGGGDSGMLTLYNVTHILSPGKEPLIAQKQKHTGAVRALDFNPFQGNLLASGASDSEIFIWDLNHLTVPMTPGSKSQNPPEDIKALSWNRQVQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSSRMNCSGLAWNPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLSSAKDNQIFCWNLSSSEVVYKLPTQSSWCFDVQWCPRNPPAFSAVSFDGWISLYSVMGRSWEAQQHMRQADKVPEQVAQASLIPPLKKPPKWMRRPAGVSFAFGGKLVTFGLPSIPVQQVPQPCPRPVFISQVITESEFLTRSVVLQEALGSGNLLNYCQSKIQQASRPSEKTLWQFLKVTLEHDSRLKFLRLLGYSRDELQKKVDTCLKSDSKSQESPQLEAVDLKSDRAHTLCSQASRHTAKEASASSAFFDELIPQNMTPWEIPTTEDTDGLLSQALLLGELRSAVELCLKEERFADAIILAQAGDAELLKWTQERYLAKRRTKTSSLLACVVKKNWKDLVCACSLKNWREALALLLTYSGPEKFPELCDMLGARMEHEGGRELTSEARLCYVCSGSVERLVESWADSQQASSPVALQELMEQVTVLSRSLELLQGSHKMSPGPATTHRFTQYASLLAAQGSLAIAMSVLPSDCTQPAVLQLKDRLFHAQGSTVLGRQAPAFPFPRVAVGAALHPKETSSHRMGFQPPRQVPAPSVRPRAAAQPSVMPFLPSHPIPSVGSWTQSSSDYRVPKPQATLPVHFVPGVRPAFSQPQPFGGQSVQAINPVGFCGTWPLPGPTPVMAPPDVMQPGSTHLPETPRLLPLPPVGPPGPTPLSSQPAASPVTFSVAHPPGGPGAPRSSALPSSGILATRPGPQDTWKVAPASQENLQRKKLPETFMPPAPIITAPLMSLGPEPQQALLPQSLVSGASLPPPGAPRECSLQQLQPLPPEKTQKELPPEHQCLKDSFEALLQRCSLTATDLKTKRKLDEAAHRLECLYEKLCEGTLSPHVLAGLHEVARCVDAGSFEQGLAVHAQVVSCSSFSEVSSFMPVLKAVLTIAHKLQG", "length": 1164 }, "evidence": [ { "id": "A0A8V0ZFZ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZFZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38968-1", "protein_name": "Protein transport protein SEC31", "gene_name": "SEC31", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVKLAEFSRTATFAWSHDKIPLLVSGTVSGTVDANFSTDSSLELWSLLAADSEKPIASLQVDSKFNDLDWSHNNKIIAGALDNGSLELYSTNEANNAINSMARFSNHSSSVKTVKFNAKQDNVLASGGNNGEIFIWDMNKCTESPSNYTPLTPGQSMSSVDEVISLAWNQSLAHVFASAGSSNFASIWDLKAKKEVIHLSYTSPNSGIKQQLSVVEWHPKNSTRVATATGSDNDPSILIWDLRNANTPLQTLNQGHQKGILSLDWCHQDEHLLLSSGRDNTVLLWNPESAEQLSQFPARGNWCFKTKFAPEAPDLFACASFDNKIEVQTLQNLTNTLDEQETETKQQESETDFWNNVSREESKEKPTVFHLQAPTWYGEPSPAAHWAFGGKLVQITPDGKGVSITNPKISGLESNTTLSEALKTKDFKPLINQRLVKVIDDVNEEDWNLLEKLSMDGTEEFLKEALAFDNDESDAQDDANNEKEDDGEEFFQQIETNFQPEGDFSLSGNIEQTISKNLVSGNIKSAVKNSLENDLLMEAMVIALDSNNERLKESVKNAYFAKYGSKSSLSRILYSISKREVDDLVENLDVSQWKFISKAIQNLYPNDIAQRNEMLIKLGDRLKENGHRQDSLTLYLAAGSLDKVASIWLSEFPDLEDKLKKDNKTIYEAHSECLTEFIERFTVFSNFINGSSTINNEQLIAKFLEFINLTTSTGNFELATEFLNSLPSDNEEVKTEKARVLIASGKSLPAQNPATATTSKAKYTNAKTNKNVPVLPTPGMPSTTSIPSMQAPFYGMTPGASANALPPKPYVPATTTSAPVHTEGKYAPPSQPSMASPFVNKTNSSTRLNSFAPPPNPYATATVPATNVSTTSIPQNTFAPIQPGMPIMGDYNAQSSSIPSQPPINAVSGQTPHLNRKANDGWNDLPLKVKEKPSRAKAVSVAPPNILSTPTPLNGIPANAASTMPPPPLSRAPSSVSMVSPPPLHKNSRVPSLVATSESPRASISNPYAPPQSSQQFPIGTISTANQTSNTAQVASSNPYAPPPQQRVATPLSGGVPPAPLPKASNPYAPTATTQPNGSSYPPTGPYTNNHTMTSPPPVFNKPPTGPPPISMKKRSNKLASIEQNPSQGATYPPTLSSSASPLQPSQPPTLASQVNTSAENVSHEIPADQQPIVDFLKEELARVTPLTPKEYSKQLKDCDKRLKILFYHLEKQDLLTQPTIDCLHDLVALMKEKKYKEAMVIHANIATNHAQEGGNWLTGVKRLIGIAEATLN", "length": 1273 }, "evidence": [ { "id": "A0A8V0ZFZ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZFZ7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3TZ89-1", "protein_name": "Protein transport protein Sec31B", "gene_name": "Sec31b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLKELEKPAVQAWSPARQYPVYLATGTSAQQLDASFSTNATLEIFEIDFRDPSLDLKHKGILSVSSRFHKLIWGSFGSGLLENSGVIAGGGDNGTLTLYNVTHVLSSGKEPLIAQKQKHTGAVRALDFNPFQGNLLASGASDSEIFIWDLNHLSVPMTPGPKSQNPPEDIKALSWNLQVQHILASAHPSGKAVVWDLRKNEPIIKVSSHSSRMNCSGLAWNPDIATQLVLCSEDDQLPVIQLWDLRFASSPLKVLESHSRGILSMSWNQADAELLLSTAKDSQIFCWNLSSSEVVYKLPTQSSWCFDVQWCPQSPPVFSAVSFDGWISLCSVMGRSWEAQHMRQADKVPEQVAQASLIPPLKKPPKWMRRPAGGSFAFGGKLVTFGLPSIPVQPVAQACSRPVFISQVITESEVLTRSVVLQEALGSGNLLNYCQSKVQQASLPCEKILWQFLKVTLEQDSRPKFLGLLGYSREELQKKVDTCLKSDSKSQESPQLEAVDLKSDRAHSPCAQASKHTAKEASESSAFFDELIPQNMTPWEIPTTEDTDGLLSQALLLGELRSAVELCLKEERFADAIILAQAGDAELLKWTQERYLAKRRTKTSSLLACVVKKNWKDLVCACRLKNWREALALLLTYSGPEKFPELCDMLGTRMEQEGGRALTSEARLCYVCSGSVERLVESWAKFQQASSPMALQELMEQVTVLSRSLELLQGSNKMSPGPATTHRLTQYANLLAAQGSLATAMSFLPSDCIQPGVQQLRDRLFHAQGSAVLGQQAPAFPFPRVAVGAALHSKETSSYRRGLQPPQQVPAPSVRPRTTAQPSSVMPFSPSQPSPSQGSSDHRVLRPQAILPGHFVPGVRPALSPPQLSGGQSVPAVNPAGFCGAWPLPGPTPVMASPDFMQPGSTHLPETPRLLPLPPVGPPGPNPLSSQLPASPVTFSVAPPPGGPRAPCSSALPSSGILATCPGPQDSWKVSPASQGNLQRKKLPETFMPPAPITAPLRSLGPEPQQALLPQPLVSSATLPPPGAPRECSLQQLQPLPPERTEKELPPEHQCVKDSFEALLQRCSLTATDLKTKRKLEEAARRLECLYEKLCEGTLSPHVLAGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPMLKAVLTIAHKLQG", "length": 1158 }, "evidence": [ { "id": "A0A8V0ZFZ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZFZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQW1-1", "protein_name": "Protein transport protein Sec31B", "gene_name": "SEC31B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLKELERPAVQAWSPASQYPLYLATGTSAQQLDSSFSTNGTLEIFEVDFRDPSLDLKHRGVLSALSRFHKLVWGSFGSGLLESSGVIVGGGDNGMLILYNVTHILSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQAQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQILCRNLGSSEVVYKLPTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVMGRSWEVQHMRQADKISSSFSKGQPLPPLQVPEQVAQAPLIPPLKKPPKWIRRPTGVSFAFGGKLVTFGLPSTPAHLVPQPCPRLVFISQVTTESEFLMRSAELQEALGSGNLLNYCQNKSQQALLQSEKMLWQFLKVTLEQDSRMKFLKLLGYSKDELQKKVATWLKSDVGLGESPQPKGNDLNSDRQQAFCSQASKHTTKEASASSAFFDELVPQNMTPWEIPITKDIDGLLSQALLLGELGPAVELCLKEERFADAIILAQAGGTDLLKQTQERYLAKKKTKISSLLACVVQKNWKDVVCTCSLKNWREALALLLTYSGTEKFPELCDMLGTRMEQEGSRALTSEARLCYVCSGSVERLVECWAKCHQALSPMALQDLMEKVMVLNRSLEQLRGPHGVSPGPATTYRVTQYANLLAAQGSLATAMSFLPRDCAQPPVQQLRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRPLGPGRMVSHTPAPPASFPVPYLPGDPGAPCSSVLPTTGILTPHPGPQDSWKEAPAPRGNLQRNKLPETFMPPAPITAPVMSLTPELQGILPSQPPVSSVSHAPPGVPGELSLQLQHLPPEKMERKELPPEHQSLKSSFEALLQRCSLSATDLKTKRKLEEAAQRLEYLYEKLCEGTLSPHVVAGLHEVARCVDAGSFEQGLAVHAQVAGCSSFSEVSSFMPILKAVLIIAHKLLV", "length": 1179 }, "evidence": [ { "id": "A0A8V0ZFZ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZFZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "COPII-coated vesicle cargo loading", "id": "GO:0090110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ], "pmid": "" }, { "name": "endoplasmic reticulum organization", "id": "GO:0007029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007029", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ], "pmid": "" }, { "name": "endoplasmic reticulum exit site", "id": "GO:0070971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ], "pmid": "" }, { "name": "COPII vesicle coat", "id": "GO:0030127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ], "pmid": "" }, { "name": "ER to Golgi transport vesicle membrane", "id": "GO:0012507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZFZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 554, "end_pos": 556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 769, "end_pos": 771, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZG00-1", "uniprot_ac": "A0A8V0ZG00", "uniprot_id": "A0A8V0ZG00_CHICK", "mass": { "chemical_mass": 27002.0, "monoisotopic_mass": 27002.0 }, "refseq": {}, "gene_names": [ { "name": "RAB35", "type": "recommended", "evidence": [ { "id": "A0A8V0ZG00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-35", "type": "recommended", "evidence": [ { "id": "A0A8V0ZG00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZG00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00", "locus": { "chromosome": "15", "start_pos": 9527868, "end_pos": 9489221, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020845", "url": "https://www.ensembl.org/id/ENSGALG00010020845" } ] } } ], "crossref": [ { "id": "A0A8V0ZG00", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZG00", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041815", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041815", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG00", "url": "https://www.orthodb.org/?gene=A0A8V0ZG00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47980", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47980", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8854214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGGAAVSSGCLFGKWIRARRRPLPLLPPAALPPLPAMARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMEIQLFETSAKENINVEEMFNCITELVLRAKKENLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 238, "header": "tr|A0A8V0ZG00-1|A0A8V0ZG00_CHICK Isoform 1 of Ras-related protein Rab-35 OS=Gallus gallus OX=9031 GN=RAB35 PE=1 SV=1 CANONICAL=A0A8V0ZG00-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00/entry#A0A8V0ZG00-1", "sequence": { "sequence": "MRGGAAVSSGCLFGKWIRARRRPLPLLPPAALPPLPAMARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMEIQLFETSAKENINVEEMFNCITELVLRAKKENLAKQQQQQQNDVVKLTKNSKRKKRCC", "length": 238, "header": "tr|A0A8V0ZG00-1|A0A8V0ZG00_CHICK Isoform 1 of Ras-related protein Rab-35 OS=Gallus gallus OX=9031 GN=RAB35 PE=1 SV=1 CANONICAL=A0A8V0ZG00-1" }, "locus": { "chromosome": "15", "start_pos": 9502246, "end_pos": 9489355, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050406.1", "url": "https://www.ensembl.org/id/ENSGALT00010050406.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029759.1", "url": "https://www.ensembl.org/id/ENSGALP00010029759.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-8854214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854214", "resource": "Reactome", "description": "TBC/RABGAPs" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "clathrin-coated pit", "id": "GO:0005905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005905", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "clathrin-coated endocytic vesicle", "id": "GO:0045334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "cell projection membrane", "id": "GO:0031253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031253", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "protein localization to endosome", "id": "GO:0036010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "Rab protein signal transduction", "id": "GO:0032482", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032482", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "antigen processing and presentation", "id": "GO:0019882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" }, { "name": "plasma membrane to endosome transport", "id": "GO:0048227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] }, { "id": "R-GGA-8854173", "name": "TBC RabGAPs accelerate GTP hydrolysis by RAB35", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, clathrin-coated endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZG00-1" ], "evidence": [ { "id": "R-GGA-8854173", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854173" } ] }, { "id": "R-GGA-8877612", "name": "DENND1s exchange GTP for GDP on RAB35", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, recycling endosome membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZG00-1" ], "evidence": [ { "id": "R-GGA-8877612", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8877612" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": 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The reference sequence was derived from JAENSK010000214.1. 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"MPGSPPWPRAQGGGSMQGQARPPTLLPPPPGVHTLSCLSQRHLTVASGCPAAVGASACLSGCCSVRLFTWLSVIRGVRLSIPQGVLLPVLFLLCSSVLPSVHLSVCVTHRGVCLSRASISLLGYQSVFPAACPSTHRSPHRLPDTMYTALPKSGSLFGPAPTHPGLHIWRVEKLRPVPVPESSWGVFFSGDAYLVLHLGPEERAHLHLWIGREASQDERGACALLSTQLNALLGERPVTHREVQGHESDEFMGYFPRGITYQEGGVDSAFKSAQHSAGPGPVHRLYQVKGRRNIRATERDLSWASFNTGDCFILDLGETIFTWCGAQCNVLERSRAQELAAAIRDGQRGSKVRLEMVMDGEEPPEMLQVLGPKPTLTEGSPEEDAAADRDAGMAVLYKVSDATGRMDLSEVARSCPFNQSLLCPDDCFVLDTGAGGKVYVWKGRKANEQERQAALSVAEQTITRMGYSPHTQVEILPQGRETPLFKQFFSGWK", "length": 493, "header": "tr|A0A8V0ZG34-1|A0A8V0ZG34_CHICK Isoform 1 of Macrophage-capping protein OS=Gallus gallus OX=9031 GN=CAPG PE=1 SV=1 CANONICAL=A0A8V0ZG34-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34/entry#A0A8V0ZG34-1", "sequence": { "sequence": "MPGSPPWPRAQGGGSMQGQARPPTLLPPPPGVHTLSCLSQRHLTVASGCPAAVGASACLSGCCSVRLFTWLSVIRGVRLSIPQGVLLPVLFLLCSSVLPSVHLSVCVTHRGVCLSRASISLLGYQSVFPAACPSTHRSPHRLPDTMYTALPKSGSLFGPAPTHPGLHIWRVEKLRPVPVPESSWGVFFSGDAYLVLHLGPEERAHLHLWIGREASQDERGACALLSTQLNALLGERPVTHREVQGHESDEFMGYFPRGITYQEGGVDSAFKSAQHSAGPGPVHRLYQVKGRRNIRATERDLSWASFNTGDCFILDLGETIFTWCGAQCNVLERSRAQELAAAIRDGQRGSKVRLEMVMDGEEPPEMLQVLGPKPTLTEGSPEEDAAADRDAGMAVLYKVSDATGRMDLSEVARSCPFNQSLLCPDDCFVLDTGAGGKVYVWKGRKANEQERQAALSVAEQTITRMGYSPHTQVEILPQGRETPLFKQFFSGWK", "length": 493, "header": "tr|A0A8V0ZG34-1|A0A8V0ZG34_CHICK Isoform 1 of Macrophage-capping protein OS=Gallus gallus OX=9031 GN=CAPG PE=1 SV=1 CANONICAL=A0A8V0ZG34-1" }, "locus": { "chromosome": "22", "start_pos": 4573555, "end_pos": 4569821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046189.1", "url": "https://www.ensembl.org/id/ENSGALT00010046189.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027524.1", "url": "https://www.ensembl.org/id/ENSGALP00010027524.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "barbed-end actin filament capping", "id": "GO:0051016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051016", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" } ], "pmid": "" }, { "name": "actin polymerization or depolymerization", "id": "GO:0008154", "url": 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"evidence": [ { "id": "A0A8V0ZG34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG34" }, { "id": "PF00626", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00626" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gelsolin-like", "eco_id": "ECO_0000259", "start_pos": 176, "end_pos": 252, "start_aa": "Pro", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 418, "end_pos": 420 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"ac": "XP_015144274", "name": "ligand-dependent corepressor isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144274" }, "gene_names": [ { "name": "LCOR", "type": "recommended", "evidence": [ { "id": "A0A8V0ZG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35" } ] }, { "name": "LCOR", "type": "synonym", "evidence": [ { "id": "XP_015144274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144274" } ] } ], "protein_names": [ { "name": "Ligand dependent nuclear receptor corepressor", "type": "synonym", "evidence": [ { "id": "A0A8V0ZG35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35/entry#names_and_taxonomy" } ] }, { "name": "ligand-dependent corepressor isoform X6", "type": "synonym", "evidence": [ { "id": "XP_015144274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144274" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015144274.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015144274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144274" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LCOR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35", "locus": { "chromosome": "6", "start_pos": 23206219, "end_pos": 23282636, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020866", "url": "https://www.ensembl.org/id/ENSGALG00010020866" } ] } } ], "crossref": [ { "id": "423847", "url": "https://www.ncbi.nlm.nih.gov/gene/423847", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423847", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423847", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZG35", "url": "https://www.orthodb.org/?gene=A0A8V0ZG35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14931", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14931", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14931:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14931:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015144274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015144274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRLCTHHQKQFIRVLNDIYTEVQPDCEGQQSSESESMEASTCGSGCSQQSTENQDKGATCTDPRPLSSLEPGQPGTDSTEQPAELKPMDRAESSSPALRRDFPDPPSTRLRSASPKDSSTQGYLSTLNSSSLNFHHATKSLEGQAAGHEQDASVRRCEDSKEQGAGKALVEGYISVKVANVNGSEDGLDSCLGSQKSSFRALPEEPWDPGFSVSSPHRADKENTLQCGSKASLHQDLDAKEQDMRPKPDNHLHAVAKGKVGCHLHPADKGPLDKSKEGWLPAGTAPTSHRAPTGHPRAKAASLRPSRKSKKASGLRINDYDNQCDVVYISQPITECHFESQRAVSSRRTARKSTRGYFFNGECCELPTVRTLVKGSRAEERGGSTAQRMHALVSTKPTLVLSGGSSTGAGRDGEKRVSLRLLAKGAPASREMKGRGELGSVQRELRDMRVLRSRESSVAVPLFSLSAPPSPQTEDSTAGSPPPPGSPCSQGAGGSAAPEVGAAPSGDGSSKDSDAVPAAGCATLPTTEAAVGEEDSPDVGVQTTPDLPASPEPGSPMQLCPALDAAPAADTRDHEVLPGASSTEPCGVHPSEPSPRSPELQSPEQPPATEGRNCPPESLATLQSVEVNKSTDTIPDAELSVVPGDTSLEQEEAAPASIALPVDLEGEAEQNNSLAGEKEPAEEEILPEPDGLETAEKDSISSKDSLDKKRKKGRRTLMASDRRLRSQQSQPPSEGSTEDTGSSSPVHLPGLQIKASKSPGAKRFKREGNLDGTTPAHFPDDCFHSTLLQHNEGLSTGQAPESSAEETGVTTRQTYKSILAKETASEGENSHKDDPAATGGQSQPGEMLDVCVQADAEKKSILLPTESSVPAGNVQAEVRLGDACAKEESSDSAIDTGKLEHYEEVSSQSPCPTSRVGGSKHLPAKAAKHKKVTLQFYNLRHAPTPADTAKKSLPGKESMQAVPKARDECSSGSDDPLALEDMDAEDSKPRFMEWCAEEENQELIAEFNAQYMKVQKGWIQLEKEVQPAPKVKNKADKLKEIWKSKKRTRKSRGALEVQKLSPVQMLFMKAYKLSDICQWFLETTETRSLVIVKKLNTRLPGEIPPIKVPMQKYSSSGLYPSSLQAERLKKHLKKFAATTPARNNLKNQKLWAKIRENADKAEAEEGNAAGQPPPPEAGPEELSQERGAQPTPSLPTQASTRILRKYSQLRGKLRAQHRATRTDRRGDVPGEQPGTEGKPSRKSLCINPLMSPKLALQIKVDAFPAKSPTADGAGKGRKGKSKGLEEPSPRAEQLSRKKRTLKESEATQERAGSSGKDKVLAKKAGKIKHSEVGTKAPATRKQVERSSKLAKKMSSKEKRPPKRQLEKVRLPVRKGKENTSRRAAPPPGHEELSPSPRHRPLGESSTRAQKMANKKAGGGKALPRAVRKGQEGSSSQGKRKLRAKGDCSHSKRSRLDAK", "length": 1459, "header": "tr|A0A8V0ZG35-1|A0A8V0ZG35_CHICK Isoform 1 of Ligand dependent nuclear receptor corepressor OS=Gallus gallus OX=9031 GN=LCOR PE=4 SV=1 CANONICAL=A0A8V0ZG35-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35/entry#A0A8V0ZG35-1", "sequence": { "sequence": "MVRLCTHHQKQFIRVLNDIYTEVQPDCEGQQSSESESMEASTCGSGCSQQSTENQDKGATCTDPRPLSSLEPGQPGTDSTEQPAELKPMDRAESSSPALRRDFPDPPSTRLRSASPKDSSTQGYLSTLNSSSLNFHHATKSLEGQAAGHEQDASVRRCEDSKEQGAGKALVEGYISVKVANVNGSEDGLDSCLGSQKSSFRALPEEPWDPGFSVSSPHRADKENTLQCGSKASLHQDLDAKEQDMRPKPDNHLHAVAKGKVGCHLHPADKGPLDKSKEGWLPAGTAPTSHRAPTGHPRAKAASLRPSRKSKKASGLRINDYDNQCDVVYISQPITECHFESQRAVSSRRTARKSTRGYFFNGECCELPTVRTLVKGSRAEERGGSTAQRMHALVSTKPTLVLSGGSSTGAGRDGEKRVSLRLLAKGAPASREMKGRGELGSVQRELRDMRVLRSRESSVAVPLFSLSAPPSPQTEDSTAGSPPPPGSPCSQGAGGSAAPEVGAAPSGDGSSKDSDAVPAAGCATLPTTEAAVGEEDSPDVGVQTTPDLPASPEPGSPMQLCPALDAAPAADTRDHEVLPGASSTEPCGVHPSEPSPRSPELQSPEQPPATEGRNCPPESLATLQSVEVNKSTDTIPDAELSVVPGDTSLEQEEAAPASIALPVDLEGEAEQNNSLAGEKEPAEEEILPEPDGLETAEKDSISSKDSLDKKRKKGRRTLMASDRRLRSQQSQPPSEGSTEDTGSSSPVHLPGLQIKASKSPGAKRFKREGNLDGTTPAHFPDDCFHSTLLQHNEGLSTGQAPESSAEETGVTTRQTYKSILAKETASEGENSHKDDPAATGGQSQPGEMLDVCVQADAEKKSILLPTESSVPAGNVQAEVRLGDACAKEESSDSAIDTGKLEHYEEVSSQSPCPTSRVGGSKHLPAKAAKHKKVTLQFYNLRHAPTPADTAKKSLPGKESMQAVPKARDECSSGSDDPLALEDMDAEDSKPRFMEWCAEEENQELIAEFNAQYMKVQKGWIQLEKEVQPAPKVKNKADKLKEIWKSKKRTRKSRGALEVQKLSPVQMLFMKAYKLSDICQWFLETTETRSLVIVKKLNTRLPGEIPPIKVPMQKYSSSGLYPSSLQAERLKKHLKKFAATTPARNNLKNQKLWAKIRENADKAEAEEGNAAGQPPPPEAGPEELSQERGAQPTPSLPTQASTRILRKYSQLRGKLRAQHRATRTDRRGDVPGEQPGTEGKPSRKSLCINPLMSPKLALQIKVDAFPAKSPTADGAGKGRKGKSKGLEEPSPRAEQLSRKKRTLKESEATQERAGSSGKDKVLAKKAGKIKHSEVGTKAPATRKQVERSSKLAKKMSSKEKRPPKRQLEKVRLPVRKGKENTSRRAAPPPGHEELSPSPRHRPLGESSTRAQKMANKKAGGGKALPRAVRKGQEGSSSQGKRKLRAKGDCSHSKRSRLDAK", "length": 1459, "header": "tr|A0A8V0ZG35-1|A0A8V0ZG35_CHICK Isoform 1 of Ligand dependent nuclear receptor corepressor OS=Gallus gallus OX=9031 GN=LCOR PE=4 SV=1 CANONICAL=A0A8V0ZG35-1" }, "locus": { "chromosome": "6", "start_pos": 23217436, "end_pos": 23213060, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050443.1", "url": "https://www.ensembl.org/id/ENSGALT00010050443.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029775.1", "url": "https://www.ensembl.org/id/ENSGALP00010029775.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1192, "start_aa": "Thr", "end_pos": 1192, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1192", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423847", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423847", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35" } ], "pmid": "" }, { "name": "cellular response to estradiol stimulus", "id": "GO:0071392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071392", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35" } ], "pmid": "" }, { "name": "nuclear estrogen receptor binding", "id": "GO:0030331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35" } ], "pmid": "" }, { "name": "ubiquitin-specific protease binding", "id": "GO:1990381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35" } ], "pmid": "" }, { "name": "histone methyltransferase binding", "id": "GO:1990226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35" } ], "pmid": "" }, { "name": "transcription corepressor binding", "id": "GO:0001222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1379, "end_pos": 1381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1192 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 1379, "end_pos": 1381 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 629, "end_pos": 631 }, { "start_pos": 672, "end_pos": 674 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZHG5-1", "uniprot_ac": "A0A8V0ZHG5", "uniprot_id": "A0A8V0ZHG5_CHICK", "mass": { "chemical_mass": 36277.0, "monoisotopic_mass": 36277.0 }, "refseq": {}, "gene_names": [ { "name": "GRAMD2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5" } ] } ], "protein_names": [ { "name": "GRAM domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZHG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GRAMD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5", "locus": { "chromosome": "10", "start_pos": 1599284, "end_pos": 1607206, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021093", "url": "https://www.ensembl.org/id/ENSGALG00010021093" } ] } } ], "crossref": [ { "id": "A0A8V0ZHG5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHG5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13220", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13220", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042624", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042624", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG41", "url": "https://www.orthodb.org/?gene=A0A8V0ZG41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHE7", "url": "https://www.orthodb.org/?gene=A0A8V0ZHE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHG5", "url": "https://www.orthodb.org/?gene=A0A8V0ZHG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNH1", "url": "https://www.orthodb.org/?gene=A0A8V0ZNH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46973", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46973", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46973:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46973:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZG41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AAPCSARSLEALKEEDIKKCQREAAASKYNSQYHKLFKDIPTEESVLKVCSCALQRDILIQGRLYISPNWLCFYANLFGKDIKVVIPVVSVQLIKKHKTARLLPNGLAITTTASRKYIFVSLISRDSVYDVLRRVCTHLQVSSKKSLSLKELTEEPDAVSLEVIVPEGKWRKVSPASLSLSLPDADYQCIHRTSVSSLSAKESFTSEEPLASVCSCSSESKWYPGLHHERGGQQGQGGDCPSPLCSCEAPSGVLCPESAINTEEELEAEQGCVAELRPSDYQLLKIFIVLICLLVVSSSYLAFRIFRLEQQLCSLNRDYLSRGHRR", "length": 326, "header": "tr|A0A8V0ZHG5-1|A0A8V0ZHG5_CHICK Isoform 1 of GRAM domain containing 2 OS=Gallus gallus OX=9031 GN=GRAMD2 PE=4 SV=1 CANONICAL=A0A8V0ZHG5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5/entry#A0A8V0ZG41-1", "sequence": { "sequence": "MTAPGSAGPPGSLEALKEEDIKKCQREAAASKYNSQYHKLFKDIPTEESVLKVCSCALQRDILIQGRLYISPNWLCFYANLFGKDIKVVIPVVSVQLIKKHKTARLLPNGLAITTTASRKYIFVSLISRDSVYDVLRRVCTHLQVSSKKSLSLKELTEEPDAVSLEVIVPEGKWRKVSPASLSLSLPDADYQCIHRTSVSSLSAKESFTSEEPLASESAINTEEELEAEQGCVAELRPSDYQLLKIFIVLICLLVVSSSYLAFRIFRLEQQLCSLNRDYLSRGHRR", "length": 286, "header": "tr|A0A8V0ZG41-1|A0A8V0ZHG5_CHICK Computationally mapped isoform of GRAM domain containing 2 OS=Gallus gallus OX=9031 GN=GRAMD2 PE=4 SV=1 CANONICAL=A0A8V0ZHG5-1" }, "locus": { "chromosome": "10", "start_pos": 1607195, "end_pos": 1600200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051056.1", "url": "https://www.ensembl.org/id/ENSGALT00010051056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030247.1", "url": "https://www.ensembl.org/id/ENSGALP00010030247.1" } ] } }, { "isoform_ac": "A0A8V0ZHE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5/entry#A0A8V0ZHE7-1", "sequence": { "sequence": "EEPPAHAGPRQAAGGAQGAQRGGPGRQAASKYNSQYHKLFKDIPTEESVLKVCSCALQRDILIQGRLYISPNWLCFYANLFGKDIKVVIPVVSVQLIKKHKTARLLPNGLAITTTASRKYIFVSLISRDSVYDVLRRVCTHLQVSSKKSLSLKELTEEPDAVSLEVIVPEGKWRKVSPASLSLSLPDADYQCIHRTSVSSLSAKESFTSEEPLASESAINTEEELEAEQGCVAELRPSDYQLLKIFIVLICLLVVSSSYLAFRIFRLEQQLCSLNRDYLSRGHRR", "length": 285, "header": "tr|A0A8V0ZHE7-1|A0A8V0ZHE7_CHICK Computationally mapped isoform of GRAM domain containing 2 OS=Gallus gallus OX=9031 GN=GRAMD2 PE=4 SV=1 CANONICAL=A0A8V0ZHG5-1" }, "locus": { "chromosome": "10", "start_pos": 1606808, "end_pos": 1600200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051054.1", "url": "https://www.ensembl.org/id/ENSGALT00010051054.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030244.1", "url": "https://www.ensembl.org/id/ENSGALP00010030244.1" } ] } }, { "isoform_ac": "A0A8V0ZHG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5/entry#A0A8V0ZHG5-1", "sequence": { "sequence": "AAPCSARSLEALKEEDIKKCQREAAASKYNSQYHKLFKDIPTEESVLKVCSCALQRDILIQGRLYISPNWLCFYANLFGKDIKVVIPVVSVQLIKKHKTARLLPNGLAITTTASRKYIFVSLISRDSVYDVLRRVCTHLQVSSKKSLSLKELTEEPDAVSLEVIVPEGKWRKVSPASLSLSLPDADYQCIHRTSVSSLSAKESFTSEEPLASVCSCSSESKWYPGLHHERGGQQGQGGDCPSPLCSCEAPSGVLCPESAINTEEELEAEQGCVAELRPSDYQLLKIFIVLICLLVVSSSYLAFRIFRLEQQLCSLNRDYLSRGHRR", "length": 326, "header": "tr|A0A8V0ZHG5-1|A0A8V0ZHG5_CHICK Isoform 1 of GRAM domain containing 2 OS=Gallus gallus OX=9031 GN=GRAMD2 PE=4 SV=1 CANONICAL=A0A8V0ZHG5-1" }, "locus": { "chromosome": "10", "start_pos": 1606648, "end_pos": 1600200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051053.1", "url": "https://www.ensembl.org/id/ENSGALT00010051053.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030243.1", "url": "https://www.ensembl.org/id/ENSGALP00010030243.1" } ] } }, { "isoform_ac": "A0A8V0ZNH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5/entry#A0A8V0ZNH1-1", "sequence": { "sequence": "HAGPRQAAGGAQGAQRGGPGRQPRGPEGGGHQEVPEGSGCQQVQLPVPQAVQGHPDGGECAERWAAVCGAGQAVWGHRALTWLCSAVCSCALQRDILIQGRLYISPNWLCFYANLFGKDIKVVIPVVSVQLIKKHKTARLLPNGLAITTTASRKYIFVSLISRDSVYDVLRRVCTHLQVSSKKSLSLKELTEEPDAVSLEVIVPEGKWRKVSPASLSLSLPDADYQCIHRTSVSSLSAKESFTSEEPLASESAINTEEELEAEQGCVAELRPSDYQLLKIFIVLICLLVVSSSYLAFRIFRLEQQLCSLNRDYLSRGHRR", "length": 320, "header": "tr|A0A8V0ZNH1-1|A0A8V0ZNH1_CHICK Computationally mapped isoform of GRAM domain containing 2 OS=Gallus gallus OX=9031 GN=GRAMD2 PE=4 SV=1 CANONICAL=A0A8V0ZHG5-1" }, "locus": { "chromosome": "10", "start_pos": 1606793, "end_pos": 1600200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051055.1", "url": "https://www.ensembl.org/id/ENSGALT00010051055.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030246.1", "url": "https://www.ensembl.org/id/ENSGALP00010030246.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5" } ], "pmid": "" }, { "name": "organelle membrane contact site", "id": "GO:0044232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044232", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of store-operated calcium entry", "id": "GO:2001256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001256", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5" } ], "pmid": "" }, { "name": "endoplasmic reticulum-plasma membrane tethering", "id": "GO:0061817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZHG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG5" }, { "id": "SM00568", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00568" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GRAM", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 98, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZG44-1", "uniprot_ac": "A0A8V0ZG44", "uniprot_id": "A0A8V0ZG44_CHICK", "mass": { "chemical_mass": 11030.0, "monoisotopic_mass": 11030.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Hes family bHLH transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZG44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG44/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG44" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG44", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZG44", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZG44", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10985", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10985", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZG44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "HGARRRGGSAAHKGTLKPLLEKRRRARINESLNQLKTLILPLVCKDSSRCSKLEKADILEMTVQFLREVPAAPSAPGEAPNPPPTRRARPDAHGHLSAEPS", "length": 101, "header": "tr|A0A8V0ZG44-1|A0A8V0ZG44_CHICK Isoform 1 of Hes family bHLH transcription factor 2 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZG44-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG44/entry#A0A8V0ZG44-1", "sequence": { "sequence": "HGARRRGGSAAHKGTLKPLLEKRRRARINESLNQLKTLILPLVCKDSSRCSKLEKADILEMTVQFLREVPAAPSAPGEAPNPPPTRRARPDAHGHLSAEPS", "length": 101, "header": "tr|A0A8V0ZG44-1|A0A8V0ZG44_CHICK Isoform 1 of Hes family bHLH transcription factor 2 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZG44-1" }, "locus": { "chromosome": "21", "start_pos": 608759, "end_pos": 608083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046215.1", "url": "https://www.ensembl.org/id/ENSGALT00010046215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027534.1", "url": "https://www.ensembl.org/id/ENSGALP00010027534.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG44" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG44" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG44" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZG44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG44" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 69, "start_aa": "His", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 29, "end_pos": 31 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZG48-1", "uniprot_ac": "A0A8V0ZG48", "uniprot_id": "A0A8V0ZG48_CHICK", "mass": { "chemical_mass": 81002.0, "monoisotopic_mass": 81002.0 }, "refseq": { "ac": "XP_421126", "name": "C-Jun-amino-terminal kinase-interacting protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421126" }, "gene_names": [ { "name": "MAPK8IP1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZG48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ] }, { "name": "MAPK8IP1", "type": "synonym", "evidence": [ { "id": "XP_421126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421126" } ] } ], "protein_names": [ { "name": "C-Jun-amino-terminal kinase-interacting protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_421126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421126" } ] }, { "name": "Mitogen-activated protein kinase 8 interacting protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZG48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_421126.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421126" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAPK8IP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48", "locus": { "chromosome": "5", "start_pos": 23459956, "end_pos": 23474048, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022041", "url": "https://www.ensembl.org/id/ENSGALG00010022041" } ] } } ], "crossref": [ { "id": "A0A8V0ZG48", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZG48", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01212", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01212", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11943", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11943", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423202", "url": "https://www.ncbi.nlm.nih.gov/gene/423202", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GHHRERI", "url": "https://omabrowser.org/oma/group/GHHRERI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG48", "url": "https://www.orthodb.org/?gene=A0A8V0ZG48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNM7", "url": "https://www.orthodb.org/?gene=A0A8V0ZNM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47437", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47437", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47437:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47437:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421126", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEREKGAASPPASSPFLGLHLASPPNFRLTHDISLEEFEDEDLSEITDECGISLHCKDSLATRGRVSRAGGAARAAGGGEGGRLQAEMLQLDLIDAAGDAPAEEQTAPEPLQKEPPPASTDSYRPKRPTTLNLFPQVPRSQGPRGAGGTWEPHPAGGTGTAKAPPGQLVPTSVQTCGEDTLNNNSLGKKHSWQERVSRSSSPLKTGEQTPPHDHVCLSDEVNHQNSTTSTKDRGTSTESPCRRTAATQMAPACVASSRPPEKHQAASRPPPHGASVVVVTSRAPEAHRDRIRYQTDVRLEATEEIYLTPVQKNSDPLETEKPFLSQSSENRMSISSDIDTSSYSALAGKTNPSISEEDEVLDYMSSPDKTSLPRASCGGGSSGYRPGHGLQRASVSSDTSALSYDSVKYTLVVDENVQLELVSLKQCYSGYSDESDSATVYDNCVSSPYESAIGEEYEEDALKRDSVCLSEDSTPEADIHFSKKFLNVFMSGRARSSSAESFGLFSCMINGEEQEQTHRAVFRFVPRHADELELEVDDPLLVEVQAEDYWYEAYNMRTGDRGIFPAYYAIEVTKDPDHITALAKSNDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIAVKADDSKEHSKVNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEESTKPLAESVGRAFQQFYKEYVEYTCPTEDIYLE", "length": 738, "header": "tr|A0A8V0ZG48-1|A0A8V0ZG48_CHICK Isoform 1 of Mitogen-activated protein kinase 8 interacting protein 1 OS=Gallus gallus OX=9031 GN=MAPK8IP1 PE=3 SV=1 CANONICAL=A0A8V0ZG48-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48/entry#A0A8V0ZG48-1", "sequence": { "sequence": "MAEREKGAASPPASSPFLGLHLASPPNFRLTHDISLEEFEDEDLSEITDECGISLHCKDSLATRGRVSRAGGAARAAGGGEGGRLQAEMLQLDLIDAAGDAPAEEQTAPEPLQKEPPPASTDSYRPKRPTTLNLFPQVPRSQGPRGAGGTWEPHPAGGTGTAKAPPGQLVPTSVQTCGEDTLNNNSLGKKHSWQERVSRSSSPLKTGEQTPPHDHVCLSDEVNHQNSTTSTKDRGTSTESPCRRTAATQMAPACVASSRPPEKHQAASRPPPHGASVVVVTSRAPEAHRDRIRYQTDVRLEATEEIYLTPVQKNSDPLETEKPFLSQSSENRMSISSDIDTSSYSALAGKTNPSISEEDEVLDYMSSPDKTSLPRASCGGGSSGYRPGHGLQRASVSSDTSALSYDSVKYTLVVDENVQLELVSLKQCYSGYSDESDSATVYDNCVSSPYESAIGEEYEEDALKRDSVCLSEDSTPEADIHFSKKFLNVFMSGRARSSSAESFGLFSCMINGEEQEQTHRAVFRFVPRHADELELEVDDPLLVEVQAEDYWYEAYNMRTGDRGIFPAYYAIEVTKDPDHITALAKSNDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIAVKADDSKEHSKVNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEESTKPLAESVGRAFQQFYKEYVEYTCPTEDIYLE", "length": 738, "header": "tr|A0A8V0ZG48-1|A0A8V0ZG48_CHICK Isoform 1 of Mitogen-activated protein kinase 8 interacting protein 1 OS=Gallus gallus OX=9031 GN=MAPK8IP1 PE=3 SV=1 CANONICAL=A0A8V0ZG48-1" }, "locus": { "chromosome": "5", "start_pos": 23474013, "end_pos": 23460897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053580.1", "url": "https://www.ensembl.org/id/ENSGALT00010053580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032285.1", "url": "https://www.ensembl.org/id/ENSGALP00010032285.1" } ] } }, { "isoform_ac": "A0A8V0ZNM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48/entry#A0A8V0ZNM7-1", "sequence": { "sequence": "MAEREKGAASPPASSPFLGLHLASPPNFRLTHDISLEEFEDEDLSEITDECGISLHCKDSLATRGRVSRAGGAARAAGGGEGGRLQAEMLQLDLIDAAGDAPAEEQTAPEPLQKEPPPASTDSYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQERVSRSSSPLKTGEQTPPHDHVCLSDEVNHQNSTTSTKDRGTSTESPCRRTAATQMAPACVASSRPPEKHQAASRPPPHGASVVVVTSRAPEAHRDRIRYQTDVRLEATEEIYLTPVQKNSDPLETEKPFLSQSSENRMSISSDIDTSSYSALAGKTNPSISEEDEVLDYMSSPDKTSLPRASCGGGSSGYRPGHGLQRASVSSDTSALSYDSVKYTLVVDENVQLELVSLKQCYSGYSDESDSATVYDNCVSSPYESAIGEEYEEDALKRDSVCLSEDSTPEADIHFSKKFLNVFMSGRARSSSAESFGLFSCMINGEEQEQTHRAVFRFVPRHADELELEVDDPLLVEVQAEDYWYEAYNMRTGDRGIFPAYYAIEVTKDPDHITALAKSNDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIAVKADDSKEHSKVNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEESTKPLAESVGRAFQQFYKEYVEYTCPTEDIYLE", "length": 701, "header": "tr|A0A8V0ZNM7-1|A0A8V0ZNM7_CHICK Computationally mapped isoform of Mitogen-activated protein kinase 8 interacting protein 1 OS=Gallus gallus OX=9031 GN=MAPK8IP1 PE=3 SV=1 CANONICAL=A0A8V0ZG48-1" }, "locus": { "chromosome": "5", "start_pos": 23474013, "end_pos": 23460897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053588.1", "url": "https://www.ensembl.org/id/ENSGALT00010053588.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032288.1", "url": "https://www.ensembl.org/id/ENSGALP00010032288.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287AQ99-1", "protein_name": "Mitogen-activated protein kinase 8 interacting protein 1", "gene_name": "MAPK8IP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAERESGGLGGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAGLLSGGGGGGGGSGGGGSRLQAEMLQMDLIDATGDTPGAEDDEEEDEEERAARRPGAGPPEAEPRQETAPRGQSQGPGGGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQSSPATTKDRGTSTDSPCRRSAATQMAPPSGPPAAPPGGRGHAHRDRIHYQADVRLEATEEIYLTPVQRPPDPAEPTSAFLPPAESRMSVSSDPDPAAYPSTAGRPHPSISEEDEGFDCLSSPERAEPPAGGWRASLGEPPPPPRASLSSDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDESDSATVYDNCASASSPYESAIGEEYEEAPRPRPSACLSEDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCVINGEEQEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGIFPAYYAIEVTKEPEHMAALTKNSDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCILEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEESTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE", "length": 711 }, "evidence": [ { "id": "A0A8V0ZG48", "url": "https://omabrowser.org/oma/group/A0A8V0ZG48/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9R237-1", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 1", "gene_name": "Mapk8ip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAERESGLSGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAGLLSAGSSGSAGSRLQAEMLQMDLIDAASDTPGAEDDEEDDDELAAQRPGVGPSKAESGQEPASRSQGQGQGPGTGSGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQGSPVPTQDRGTSTDSPCRRTAATQMAPPSGPPATAPGGRGHSHRDRIHYQADVRLEATEEIYLTPVQRPPDPAEPTSTFLPPTESRMSVSSDPDPAAYSVTAGRPHPSISEEDEGFDCLSSPEQAEPPGGGWRGSLGEPPPPPRASLSSDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDESDSATVYDNCASASSPYESAIGEEYEEAPQPRPPTCLSEDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCVINGEEHEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWIDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADEAQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE", "length": 708 }, "evidence": [ { "id": "A0A8V0ZG48", "url": "https://omabrowser.org/oma/group/A0A8V0ZG48/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UQF2-1", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 1", "gene_name": "MAPK8IP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAERESGGLGGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAGLLSAGGGGAGSRLQAEMLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQSGPAPTTDRGTSTDSPCRRSTATQMAPPGGPPAAPPGGRGHSHRDRIHYQADVRLEATEEIYLTPVQRPPDAAEPTSAFLPPTESRMSVSSDPDPAAYPSTAGRPHPSISEEEEGFDCLSSPERAEPPGGGWRGSLGEPPPPPRASLSSDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDESDSATVYDNCASVSSPYESAIGEEYEEAPRPQPPACLSEDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCIINGEEQEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE", "length": 711 }, "evidence": [ { "id": "A0A8V0ZG48", "url": "https://omabrowser.org/oma/group/A0A8V0ZG48/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WVI9-1", "protein_name": "C-Jun-amino-terminal kinase-interacting protein 1", "gene_name": "Mapk8ip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAERESGLGGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAGLLSAGSSGSAGSRLQAEMLQMDLIDAAGDTPGAEDDEEEEDDELAAQRPGVGPPKAESNQDPAPRSQGQGPGTGSGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQGSPVPTQDRGTSTDSPCRRSAATQMAPPSGPPATAPGGRGHSHRDRIHYQADVRLEATEEIYLTPVQRPPDPAEPTSTFMPPTESRMSVSSDPDPAAYSVTAGRPHPSISEEDEGFDCLSSPERAEPPGGGWRGSLGEPPPPPRASLSSDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDESDSATVYDNCASASSPYESAIGEEYEEAPQPRPPTCLSEDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCVINGEEHEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWIDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDALEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE", "length": 707 }, "evidence": [ { "id": "A0A8V0ZG48", "url": "https://omabrowser.org/oma/group/A0A8V0ZG48/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of CD8-positive, alpha-beta T cell proliferation", "id": "GO:2000564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000564", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" }, { "name": "positive regulation of JNK cascade", "id": "GO:0046330", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046330", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" }, { "name": "JNK cascade", "id": "GO:0007254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" }, { "name": "regulation of JNK cascade", "id": "GO:0046328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046328", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" }, { "name": "cell body", "id": "GO:0044297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "kinesin binding", "id": "GO:0019894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019894", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" }, { "name": "MAP-kinase scaffold activity", "id": "GO:0005078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005078", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" }, { "name": "JUN kinase binding", "id": "GO:0008432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008432", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 670, "end_pos": 672, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": 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"sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 670, "end_pos": 672 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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{ "name": "PGC-1-related coactivator", "type": "synonym", "evidence": [ { "id": "A0A8V0ZG50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG50/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG50#function" }, { "database": "UniProtKB", "id": "ARBA00058682", "url": "https://www.uniprot.org/uniprotkb/ARBA00058682#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG50" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPRC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG50", "locus": { "chromosome": "6", "start_pos": 23293183, "end_pos": 23303060, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020889", "url": "https://www.ensembl.org/id/ENSGALG00010020889" } ] } } ], "crossref": [ { "id": "cd12624", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12624", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG50", "url": "https://www.orthodb.org/?gene=A0A8V0ZG50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15528:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15528:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZG50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALRGGAVLPAAGAGVGAGVCGASTGAASRGPAGGGASRQPALRAGSPLQCFSFEEDDLNLSLDAETIPEAEEILGTMQNYLDSSVISIIEDLSLSEGKACLDAQNELSLLTAITEILDSTDDETLSPFDTIMDAELLTSLRERENPSFQKFLSLSRPVLECKSPALEQPKGLWSLSSGGSMPETGKTNVDLAWDCIAHSLEDPSPPKKQTCSTPRVERKQGRPRAHEQLPLQRSDGEEEDEEAASSPELDSSMEAAEFCMNAPEVVAEEHEDPCVINTGDVSLSELVKSMHPYCLPTFTVCLDPESEPVAKELLNGPVVLEIVPREGENMEIPVVLQPLAPSFPDLEPQLLGTEGDAESIPVHGEEPPGDPAAETGMEEEEKPPGQEPSCAAPYSNTPVETAVSSKREICEKGRGRERARKSRKKKAEEGLSEDGRPGRGCVAHRLRSGRSRRAARPSLQVSDFLARQLEQARKEGQMELHAERAPRPRGRPRGVAGVSLPTKEPPELPKGLEPEMTDTVLEKGETAVPVEKTTEEPLAAKQPIPVEQEDKGAVQPDVGMPKQDVGVEPPQSVPAAEPSETLPKEAKPKALSLREYRMRMQHRQSSTGSRKEGKKQAASKWPSVPEPPTELADIPCLVAPARPPTETPSAQKSLEKSAGSPAGPPPANKAPAAPVPAPVPAPAPASAPAPASAPPPPVTPIPFVAPTMPPAAGVAPPGMPSPATTGAYAMYPSVPSWPCFGPQPLGCHALPPPPGAGPPGTFHMMHGLPPPPMAWPPPALPPPPPFVPGGPYGPVGWAPPSYWPGIPIPPPPVPPMAYGDPALQGAAASSVPAGGCPSTALLHGQAPPAPELPAIPVQPSPSREMETAGSQARPGVSRVSNPRRQARMVGESSFPKGPLAPAPTQPPVTPSGAAAQPSRAPPAAPAPNVAAPAQPVEEPPPLAPIQLSKAPPAVIPAEVSAAAVPAGGSPGTYPTEEPAGPAKTPVDKTPPEPPSHKPIIQALAPPPKPCRESSKPPAARPWRHQPLISPAQPSDSSQDIVQAFISEIGIEAADLSSLLEQFEKSEAKKEEAPVQPPEERRPARSAGSEPQPERKPPDSLQASELANVAGLTPPATPPHQLWKPLPTVSLLAKTKSPVSAPQEGIQRTAKLAKAKALPQSRLQGRSPAPGSAAPSHVCSGDHDYCIPRTAHLENSSIAGTQPPATESGSRWNVKHHRDITIKPISSLTKRTLDQPKPAPATTVGPSQESPGAACPTPLDYRTSVPSKAITGGDSPATSVLLSPAASPCRDQEVWTSSTQPGRVAAKKSLRCYRRPQDSPSPSAGSWRAGRSRASRSFSSSSDGASESSSSSSSSRSRSRSLSPPPKRWRGYRSRCSHSSSSRSSCGSCGRSRDRSSSSSSSSSYSSRSPSRRQSRSRSPSPCRRSNRRRRYSYDAQDHYQRQRILQKERAIEERRVVFIGKIPSRMTRSELRHRFSVFGDIEECTLHFRSEGDNYGFVTYRYAEEAFAAIESGHKLRRPDEQPFDLCFGGRRQFCRRNYADLDSNREDFDPAPVKSKFDSLDFDTLLRQAQRSLRR", "length": 1578, "header": "tr|A0A8V0ZG50-1|A0A8V0ZG50_CHICK Isoform 1 of Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 OS=Gallus gallus OX=9031 GN=PPRC1 PE=4 SV=1 CANONICAL=A0A8V0ZG50-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG50/entry#A0A8V0ZG50-1", "sequence": { "sequence": "MAALRGGAVLPAAGAGVGAGVCGASTGAASRGPAGGGASRQPALRAGSPLQCFSFEEDDLNLSLDAETIPEAEEILGTMQNYLDSSVISIIEDLSLSEGKACLDAQNELSLLTAITEILDSTDDETLSPFDTIMDAELLTSLRERENPSFQKFLSLSRPVLECKSPALEQPKGLWSLSSGGSMPETGKTNVDLAWDCIAHSLEDPSPPKKQTCSTPRVERKQGRPRAHEQLPLQRSDGEEEDEEAASSPELDSSMEAAEFCMNAPEVVAEEHEDPCVINTGDVSLSELVKSMHPYCLPTFTVCLDPESEPVAKELLNGPVVLEIVPREGENMEIPVVLQPLAPSFPDLEPQLLGTEGDAESIPVHGEEPPGDPAAETGMEEEEKPPGQEPSCAAPYSNTPVETAVSSKREICEKGRGRERARKSRKKKAEEGLSEDGRPGRGCVAHRLRSGRSRRAARPSLQVSDFLARQLEQARKEGQMELHAERAPRPRGRPRGVAGVSLPTKEPPELPKGLEPEMTDTVLEKGETAVPVEKTTEEPLAAKQPIPVEQEDKGAVQPDVGMPKQDVGVEPPQSVPAAEPSETLPKEAKPKALSLREYRMRMQHRQSSTGSRKEGKKQAASKWPSVPEPPTELADIPCLVAPARPPTETPSAQKSLEKSAGSPAGPPPANKAPAAPVPAPVPAPAPASAPAPASAPPPPVTPIPFVAPTMPPAAGVAPPGMPSPATTGAYAMYPSVPSWPCFGPQPLGCHALPPPPGAGPPGTFHMMHGLPPPPMAWPPPALPPPPPFVPGGPYGPVGWAPPSYWPGIPIPPPPVPPMAYGDPALQGAAASSVPAGGCPSTALLHGQAPPAPELPAIPVQPSPSREMETAGSQARPGVSRVSNPRRQARMVGESSFPKGPLAPAPTQPPVTPSGAAAQPSRAPPAAPAPNVAAPAQPVEEPPPLAPIQLSKAPPAVIPAEVSAAAVPAGGSPGTYPTEEPAGPAKTPVDKTPPEPPSHKPIIQALAPPPKPCRESSKPPAARPWRHQPLISPAQPSDSSQDIVQAFISEIGIEAADLSSLLEQFEKSEAKKEEAPVQPPEERRPARSAGSEPQPERKPPDSLQASELANVAGLTPPATPPHQLWKPLPTVSLLAKTKSPVSAPQEGIQRTAKLAKAKALPQSRLQGRSPAPGSAAPSHVCSGDHDYCIPRTAHLENSSIAGTQPPATESGSRWNVKHHRDITIKPISSLTKRTLDQPKPAPATTVGPSQESPGAACPTPLDYRTSVPSKAITGGDSPATSVLLSPAASPCRDQEVWTSSTQPGRVAAKKSLRCYRRPQDSPSPSAGSWRAGRSRASRSFSSSSDGASESSSSSSSSRSRSRSLSPPPKRWRGYRSRCSHSSSSRSSCGSCGRSRDRSSSSSSSSSYSSRSPSRRQSRSRSPSPCRRSNRRRRYSYDAQDHYQRQRILQKERAIEERRVVFIGKIPSRMTRSELRHRFSVFGDIEECTLHFRSEGDNYGFVTYRYAEEAFAAIESGHKLRRPDEQPFDLCFGGRRQFCRRNYADLDSNREDFDPAPVKSKFDSLDFDTLLRQAQRSLRR", 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The reference sequence was derived from JAENSK010000214.1. 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Involved in the formation of clusters of actin bundles. 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"strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022051", "url": "https://www.ensembl.org/id/ENSGALG00010022051" } ] } } ], "crossref": [ { "id": "A0A8V0ZG68", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZG68", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07645", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07645", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11913", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11913", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035592", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035592", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG64", "url": "https://www.orthodb.org/?gene=A0A8V0ZG64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG68", "url": "https://www.orthodb.org/?gene=A0A8V0ZG68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNB0", "url": "https://www.orthodb.org/?gene=A0A8V0ZNB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14206:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14206:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRDPEEVNKLTESTYKNVMEQFNPGLRNLINLGKNYEKAVNAMVVAGRSYYDSLAKIGDISADSPVSKELGQVLVEISRTHKKLNDSLEESFKKFHKEIISELEKKTDLDVKYMTATLKRYQTEHRSKLDSLEKSQAELKKIRRKSQGARNVMKYEHKEMEYLETVSSRQTDIQRFIAEGCREALLEEKRRFCFLVDKHCSFTQHMHFYHAQCAEFLNAKLPGWQEICSDATKVPEKVKMMIEEIRTPGSTPISGTPQPSPMIERNTMIGNNFYAHNENASKVPPAPVGRAYTSPLVDMFNNPAMAPKVSPERPTNPAENSDDASLSRSTSVATGLNIMKRQKVKTIFPHTAGNNKTLLSFAQGDTIILLVSEEKDGWLYGEHESTKVKGWFPSSYTRPLEESEEKAFVPASSAAPVRSISSVNLAEKAGVVLPPPDYLGSTSDKRMESSKGTAARTPTDKPESAGLKPDMNGIVKPPFLRYILKLLIQLQLC", "length": 494, "header": "tr|A0A8V0ZG68-1|A0A8V0ZG68_CHICK Isoform 1 of BAR/IMD domain-containing adapter protein 2-like 1 OS=Gallus gallus OX=9031 GN=BAIAP2L1 PE=1 SV=1 CANONICAL=A0A8V0ZG68-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG68/entry#A0A8V0ZG64-1", "sequence": { "sequence": "MSRDPEEVNKLTESTYKNVMEQFNPGLRNLINLGKNYEKAVNAMVVAGRSYYDSLAKIGDISADSPVSKELGQVLVEISRTHKKLNDSLEESFKKFHKEIISELEKKTDLDVKYMTATLKRYQTEHRSKLDSLEKSQAELKKIRRKSQGARNVMKYEHKEMEYLETVSSRQTDIQRFIAEGCREALLEEKRRFCFLVDKHCSFTQHMHFYHAQCAEFLNAKLPGWQEICSDATKVPEKVKMMIEEIRTPGSTPISGTPQPSPMIERNTMIGNNFYAHNENASKVPPAPVGRAYTSPLVDMFNNPAMAPKVSPERPTNPAENSDDASLSRSTSVATGLNIMKRQKVKTIFPHTAGNNKTLLSFAQGDTIILLVSEEKDGWLYGEHESTKVKGWFPSSYTRPLEESEEKAFVPASSAAPVRSISSVNLAEKAGVVLPPPDYLGSTSDKRMESSKGTAARTPTDKPESAGLKPDMNGIVKPPFLRLAQSGG", "length": 488, "header": "tr|A0A8V0ZG64-1|A0A8V0ZG68_CHICK Computationally mapped isoform of BAR/IMD domain-containing adapter protein 2-like 1 OS=Gallus gallus OX=9031 GN=BAIAP2L1 PE=1 SV=1 CANONICAL=A0A8V0ZG68-1" }, "locus": { "chromosome": "14", "start_pos": 1194200, "end_pos": 1160362, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053616.1", "url": "https://www.ensembl.org/id/ENSGALT00010053616.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032301.1", "url": "https://www.ensembl.org/id/ENSGALP00010032301.1" } ] } }, { "isoform_ac": "A0A8V0ZG68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG68/entry#A0A8V0ZG68-1", "sequence": { "sequence": "MSRDPEEVNKLTESTYKNVMEQFNPGLRNLINLGKNYEKAVNAMVVAGRSYYDSLAKIGDISADSPVSKELGQVLVEISRTHKKLNDSLEESFKKFHKEIISELEKKTDLDVKYMTATLKRYQTEHRSKLDSLEKSQAELKKIRRKSQGARNVMKYEHKEMEYLETVSSRQTDIQRFIAEGCREALLEEKRRFCFLVDKHCSFTQHMHFYHAQCAEFLNAKLPGWQEICSDATKVPEKVKMMIEEIRTPGSTPISGTPQPSPMIERNTMIGNNFYAHNENASKVPPAPVGRAYTSPLVDMFNNPAMAPKVSPERPTNPAENSDDASLSRSTSVATGLNIMKRQKVKTIFPHTAGNNKTLLSFAQGDTIILLVSEEKDGWLYGEHESTKVKGWFPSSYTRPLEESEEKAFVPASSAAPVRSISSVNLAEKAGVVLPPPDYLGSTSDKRMESSKGTAARTPTDKPESAGLKPDMNGIVKPPFLRYILKLLIQLQLC", "length": 494, "header": "tr|A0A8V0ZG68-1|A0A8V0ZG68_CHICK Isoform 1 of BAR/IMD domain-containing adapter protein 2-like 1 OS=Gallus gallus OX=9031 GN=BAIAP2L1 PE=1 SV=1 CANONICAL=A0A8V0ZG68-1" }, "locus": { "chromosome": "14", "start_pos": 1194200, "end_pos": 1160541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053623.1", "url": "https://www.ensembl.org/id/ENSGALT00010053623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032306.1", "url": "https://www.ensembl.org/id/ENSGALP00010032306.1" } ] } }, { "isoform_ac": "A0A8V0ZNB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG68/entry#A0A8V0ZNB0-1", "sequence": { "sequence": "MSRDPEEVNKLTESTYKNVMEQFNPGLRNLINLGKNYEKAVNAMVVAGRSYYDSLAKIGDISADSPVSKELGQVLVEISRTHKKLNDSLEESATLKRYQTEHRSKLDSLEKSQAELKKIRRKSQGARNVMKYEHKEMEYLETVSSRQTDIQRFIAEGCREALLEEKRRFCFLVDKHCSFTQHMHFYHAQCAEFLNAKLPGWQEICSDATKVPEKVKMMIEEIRTPGSTPISGTPQPSPMIERNTMIGNNFYAHNENASKVPPAPVGRAYTSPLVDMFNNPAMAPKVSPERPTNPAENSDDASLSRSTSVATGLNIMKRQKVKTIFPHTAGNNKTLLSFAQGDTIILLVSEEKDGWLYGEHESTKVKGWFPSSYTRPLEESEEKAFVPASSAAPVRSISSVNLAEKAGVVLPPPDYLGSTSDKRMESSKGTAARTPTDKPESAGLKPDMNGIVKPPFLSGENPFATVKLRPTVTNDRSAPIIR", "length": 482, "header": "tr|A0A8V0ZNB0-1|A0A8V0ZNB0_CHICK Computationally mapped isoform of BAI1 associated protein 2 like 1 OS=Gallus gallus OX=9031 GN=BAIAP2L1 PE=1 SV=1 CANONICAL=A0A8V0ZG68-1" }, "locus": { "chromosome": "14", "start_pos": 1194200, "end_pos": 1160071, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053621.1", "url": "https://www.ensembl.org/id/ENSGALT00010053621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032305.1", "url": "https://www.ensembl.org/id/ENSGALP00010032305.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-GGA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": 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"Protein Classification" ] }, { "id": "PF00491", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00491", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-351143", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351143", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040507022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCLLRTARLSAQLLFASAAAPCRRASRFNVPPSAEFVARPVGVCSMLRLPVQTSAEGLDAAFVGVPLDTGTSNRPGARFGPQQIRAESVMVRRYNASTGAAPFDSLLVADVGDVNVNLYNLPDSCRRIRESYQKIVASGCVPLTLGGDHSITYPILQAVAEKHGPVGLVHVDAHTDTSDMALGEKIYHGTPFRRCVDEGLLDCSRVVQIGIRGSSYAPNPYKYCWDQGFRVVPAEECWMKSLVPLMGEVRQQMGDGPVYISFDIDGLDPAYAPGTGTPEIAGLTPMQALEIIRGCKGLNIVGCDLVEVAPIYDVSGNTALLGANLLFEMLCVLPGVKTMCSDRLLCSKE", "length": 350, "header": "tr|A0A8V0ZGB9-1|A0A8V0ZGB9_CHICK Isoform 1 of Agmatinase OS=Gallus gallus OX=9031 GN=AGMAT PE=3 SV=1 CANONICAL=A0A8V0ZGB9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9/entry#A0A8V0ZG75-1", "sequence": { "sequence": "MSCLLRTARLSAQLLFASAAAPCRRASRFNVPPSAEFVARPVGVCSMLRLPVQTSAEGLDAAFVGVPLDTGTSNRPGARFGPQQIRAESVMVRSCRRIRESYQKIVASGCVPLTLGGDHSITYPILQAVAEKHGPVGLVHVDAHTDTSDMALGEKIYHGTPFRRCVDEGLLDCSRVVQIGIRGSSYAPNPYKYCWDQGFRVVPAEECWMKSLVPLMGEVRQQMGDGPVYISFDIDGLDPAYAPGTGTPEIAGLTPMQALEIIRGCKGLNIVGCDLVEVAPIYDVSGNTALLGANLLFEMLCVLPGVKTM", "length": 309, "header": "tr|A0A8V0ZG75-1|A0A8V0ZGB9_CHICK Computationally mapped isoform of Agmatinase OS=Gallus gallus OX=9031 GN=AGMAT PE=3 SV=1 CANONICAL=A0A8V0ZGB9-1" }, "locus": { "chromosome": "21", "start_pos": 4905998, "end_pos": 4904081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050534.1", "url": "https://www.ensembl.org/id/ENSGALT00010050534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029831.1", "url": "https://www.ensembl.org/id/ENSGALP00010029831.1" } ] } }, { "isoform_ac": "A0A8V0ZGB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9/entry#A0A8V0ZGB9-1", "sequence": { "sequence": "MSCLLRTARLSAQLLFASAAAPCRRASRFNVPPSAEFVARPVGVCSMLRLPVQTSAEGLDAAFVGVPLDTGTSNRPGARFGPQQIRAESVMVRRYNASTGAAPFDSLLVADVGDVNVNLYNLPDSCRRIRESYQKIVASGCVPLTLGGDHSITYPILQAVAEKHGPVGLVHVDAHTDTSDMALGEKIYHGTPFRRCVDEGLLDCSRVVQIGIRGSSYAPNPYKYCWDQGFRVVPAEECWMKSLVPLMGEVRQQMGDGPVYISFDIDGLDPAYAPGTGTPEIAGLTPMQALEIIRGCKGLNIVGCDLVEVAPIYDVSGNTALLGANLLFEMLCVLPGVKTMCSDRLLCSKE", "length": 350, "header": "tr|A0A8V0ZGB9-1|A0A8V0ZGB9_CHICK Isoform 1 of Agmatinase OS=Gallus gallus OX=9031 GN=AGMAT PE=3 SV=1 CANONICAL=A0A8V0ZGB9-1" }, "locus": { "chromosome": "21", "start_pos": 4906136, "end_pos": 4904081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050527.1", "url": "https://www.ensembl.org/id/ENSGALT00010050527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029825.1", "url": "https://www.ensembl.org/id/ENSGALP00010029825.1" } ] } }, { "isoform_ac": "A0A8V0ZMD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9/entry#A0A8V0ZMD3-1", "sequence": { "sequence": "MSCLLRTARLSAQLLFASAAAPCRRASRFNVPPSAEFVARPVGVCSMLRLPVQTSAEGLDAAFVGVPLDTGTSNRPGARFGPQQIRAESVMVRRYNASTGAAPFDSLLVADVGDVNVNLYNLPDSCRRIRESYQKIVASGCVPLTLGGDHSITYPILQAVAEKHGPVGLVHVDAHTDTSDMALGEKIYHGTPFRRCVDEGLLDCSRVVQIGIRGSSYAPNPYKYCWDQGFRVVPAEECWMKSLVPLMGEVRQQMGDGPVYISFDIDGLDPAYAPGTGTPEIAGLTPMQALEIIRGCKGLNIVGCDLVEVAPIYDVSGNTALLGANLLFEMLCVLPGVKTM", "length": 340, "header": "tr|A0A8V0ZMD3-1|A0A8V0ZMD3_CHICK Computationally mapped isoform of Agmatinase OS=Gallus gallus OX=9031 GN=AGMAT PE=3 SV=1 CANONICAL=A0A8V0ZGB9-1" }, "locus": { "chromosome": "21", "start_pos": 4905998, "end_pos": 4904081, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050539.1", "url": "https://www.ensembl.org/id/ENSGALT00010050539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029833.1", "url": "https://www.ensembl.org/id/ENSGALP00010029833.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:373942", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373942", "resource": "KEGG Pathway" }, { "id": "R-GGA-351143", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351143", "resource": "Reactome", "description": "Agmatine biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AS89-1", "protein_name": "Guanidino acid hydrolase, mitochondrial", "gene_name": "Agmat", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRLLRSSWARGLGSGVATWRPSAGLFRPGCPGIRQASGASDTPHHQSPSSESPVQPVGVGVCSMMRLPLQSSPEGLDAAFIGVPLDTGTSNRPGARFGPCRIREESLMLGAVNPSTGALPFQSLRVADLGNVNVNLYNLQDSCLLIREAYQNVLAAGCIPLTLGGDQTITYPILQAVAKEHGPVGLVHVGAHTNTTDKPREEKVYHRTPFRRSVDEGLLDSKRVVQIGIRGSSRTLDPYRYSRSQGFRVVLAEDCWMKSLVPLMAEVRQQMGGKPLYISFAIDALDPAYAPGTGTPEIAGLTPSQALEIIRGCQGLNVVGCDLVEVSPPYDLSGNTALLAANLLFEMLCALPKVTTV", "length": 358 }, "evidence": [ { "id": "A0A8V0ZGB9", "url": "https://omabrowser.org/oma/group/A0A8V0ZGB9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BLC0-1", "protein_name": "Guanidino acid hydrolase, mitochondrial", "gene_name": "AGMAT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRLLASTCARGLGGRGGSRRLVSRGRARPVAGLCDPSRRLSRQASDAPRNQPPSPEFVARSVGICSMMRLPVQATPEGLDAAFVGVPLDIGTSNRPGARFGPRRIREESVLLRTTNPSTGAVPFQFLRVADLGDVNVNLYNLQDSCRLIRADYQKIVAAGCVPLTLGGDHTITYPILQAIAEKHGPVGLVHVDAHMDMADKALGEKLYHGTPFRRCVDEGLLDCKRVVQIGIRGSSTTLDTYRYSRSQGFRVVLAEDCWLKSLVPLMGEVRQQMGGRPIYISFDIDGLDPAYAPGTGTPEIAGLTPSQALEIIRGCQGLNVVGCDLVEVSPPYDPSGNTALVAANLLFEMLCVLPKVTVA", "length": 361 }, "evidence": [ { "id": "A0A8V0ZGB9", "url": "https://omabrowser.org/oma/group/A0A8V0ZGB9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q0D2L3-1", "protein_name": "Guanidino acid hydrolase, mitochondrial", "gene_name": "Agmat", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLQLLKSSWVRSAGSGVVTWRASAGLFCPGTRQASDTSDTLHHPSPSSESQVQPVRVCSMMHLPLQSSPEGLDAAFVGVPLDTGTSNRPGARFGPRRIREESLMLGTVNPSTGALPFQSLRVADLGNVNVNLYNLQDSCRLIREAYQNILATGCIPLTLGGDHTITYPILQAVAKEHGPVGLVHVGAHSNTSDKPLEDKVYHRTPFRRSVDEGLLDSKRVVQIGIRGSSRTLDPYRYSRSQGFRVVLAEDCWMKSLVPLMAEIRQQMGGVPLYISFAIDALDPAYAPGTGTPEIAGLTPSQALEIIRGCQGLNVVGCDLVEVSPPYDLSGNTALLAANLLFEMLCALPKVTTV", "length": 353 }, "evidence": [ { "id": "A0A8V0ZGB9", "url": "https://omabrowser.org/oma/group/A0A8V0ZGB9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BSE5-1", "protein_name": "Guanidino acid hydrolase, mitochondrial", "gene_name": "AGMAT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRLLASGCARGPGPGVGARPAAGLFHPGRRQSRQASDAPRNQPPSPEFVARPVGVCSMMRLPVQTSPEGLDAAFIGVPLDTGTSNRPGARFGPRRIREESVMLGTVNPSTGALPFQSLMVADLGDVNVNLYNLQDSCRRIQEAYEKIVAAGCIPLTLGGDHTITYPILQAMAKKHGPVGLLHVDAHTDTTDKALGEKLYHGAPFRRCVDEGLLDCKRVVQIGIRGSSTTLDPYRYNRSQGFRVVLAEDCWMKSLVPLMGEVRQQMGGKPIYISFDIDALDPAYAPGTGTPEIAGLTPSQALEIIRGCQGLNVMGCDLVEVSPPYDLSGNTALLAANLLFEMLCALPKVTTV", "length": 352 }, "evidence": [ { "id": "A0A8V0ZGB9", "url": "https://omabrowser.org/oma/group/A0A8V0ZGB9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9" } ], "pmid": "" }, { "name": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines", "id": "GO:0016813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9" } ], "pmid": "" }, { "name": "arginase activity", "id": "GO:0004053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004053", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9" } ], "pmid": "" }, { "name": "agmatinase activity", "id": "GO:0008783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9" } ], "pmid": "" }, { "name": "guanidinobutyrase activity", "id": "GO:0047971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9" } ], "pmid": "" }, { "name": "guanidinopropionase activity", "id": "GO:0047972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047972", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "putrescine biosynthetic process from arginine, via agmatine", "id": "GO:0033389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033389", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A8V0ZG75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG75#function" }, { "id": "A0A8V0ZG75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG75" }, { "id": "PIRSR036979-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036979-1" } ], "binding_site_uniprot": 119, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 119, "end_pos": 119, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZG75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG75#function" }, { "id": "A0A8V0ZG75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG75" }, { "id": "PIRSR036979-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036979-1" } ], "binding_site_uniprot": 142, "amino_acid": "Val", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 142, "end_pos": 142, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZG75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG75#function" }, { "id": "A0A8V0ZG75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG75" }, { "id": "PIRSR036979-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036979-1" } ], "binding_site_uniprot": 144, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 144, "end_pos": 144, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZG75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG75#function" }, { "id": "A0A8V0ZG75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG75" }, { "id": "PIRSR036979-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036979-1" } ], "binding_site_uniprot": 146, "amino_acid": "Leu", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 146, "end_pos": 146, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9#function" }, { "id": "A0A8V0ZGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9" }, { "id": "PIRSR036979-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036979-1" }, { "id": "A0A8V0ZMD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD3#function" }, { "id": "A0A8V0ZMD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD3" } ], "binding_site_uniprot": 150, "amino_acid": "His", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 150, "end_pos": 150, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9#function" }, { "id": "A0A8V0ZGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9" }, { "id": "PIRSR036979-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036979-1" }, { "id": "A0A8V0ZMD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD3#function" }, { "id": "A0A8V0ZMD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD3" } ], "binding_site_uniprot": 173, "amino_acid": "Asp", 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"binding_site_uniprot": 235, "amino_acid": "Ala", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 235, "end_pos": 235, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9#function" }, { "id": "A0A8V0ZGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB9" }, { "id": "PIRSR036979-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR036979-1" }, { "id": "A0A8V0ZMD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD3#function" }, { "id": "A0A8V0ZMD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD3" } ], "binding_site_uniprot": 264, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "1", 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"glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZG78-1", "uniprot_ac": "A0A8V0ZG78", "uniprot_id": "A0A8V0ZG78_CHICK", "mass": { "chemical_mass": 70198.0, "monoisotopic_mass": 70198.0 }, "refseq": { "ac": "XP_040506728", "name": "polyadenylate-binding protein 1-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506728" }, "gene_names": [ { "name": "PABPC1L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZG78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG78" } ] }, { "name": "PABPC1L", "type": "synonym", "evidence": [ { "id": "XP_040506728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506728" } ] } ], "protein_names": [ { "name": "Polyadenylate-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZG78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG78/entry#names_and_taxonomy" } ] }, { "name": "PABP", "type": "synonym", "evidence": [ { "id": "A0A8V0ZG78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG78/entry#names_and_taxonomy" } ] }, { "name": "polyadenylate-binding protein 1-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040506728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506728" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506728" } ] }, { "annotation": "Binds and protects the poly(A) tail of mRNA with or without an AU-rich element (ARE) and prevents mRNA deadenylation. Stimulates the translation of mRNAs to which it is bound during early development.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG78#function" }, { "database": "UniProtKB", "id": "ARBA00057784", "url": "https://www.uniprot.org/uniprotkb/ARBA00057784#function" } ] }, { "annotation": "Binds the poly(A) tail of mRNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG78#function" }, { "database": "UniProtKB", "id": "RU362004", "url": "https://www.uniprot.org/uniprotkb/RU362004#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG78" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PABPC1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG78", "locus": { "chromosome": "20", "start_pos": 5573899, "end_pos": 5583841, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022065", "url": "https://www.ensembl.org/id/ENSGALG00010022065" } ] } } ], "crossref": [ { "id": "A0A8V0ZG78", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZG78", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12378", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12379", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12379", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12380", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12380", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12381", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12381", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419189", "url": "https://www.ncbi.nlm.nih.gov/gene/419189", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419189", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419189", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNDKEWF", "url": "https://omabrowser.org/oma/group/FNDKEWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG78", "url": "https://www.orthodb.org/?gene=A0A8V0ZG78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00658", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00658", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040506728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506728", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNASGPGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVASRRSLGYAYINFQQPADAERALDTMNFEVIKGRPVRIMWSQRDPGLRKSGVGNVFIKNLDDSIDNKALYDTFSAFGNILSCKVVCDENGSRGHGFVHFETQEAATRAIQTMNGMLLNDRKVFVGHFKSRKEREAEFGARAMEFTNVYIKNFGDDMDDNRLREIFSRFGKTLSVKVMMDHTGRSKGFGFVNFEKHEEAQKAVADMNGKEINGRMVYVGRAQKRLERQSELKRKFEQMKQERVSRYQGVNLYVKNLDDGIDDERLRKEFSPYGTITSAKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVSTKPLYVALAQRKEERKAILTNQYMQRLATMRALPGPFLGSFQPPPGYFLPPIPQPQTRAAFYSPSPVVPVRPATRWSAQPTRPPPYPAATPILRAAVQPRRLLSNISTMRQASTQVPRVPPQAQRVANIGTQTISARVPSSPTLRGAPQYKYSLAVRNIQPMGSVPPGAQQVGEPAVHIQGQEPLTASMLAAAPPQEQKQMIGERLYPLIHAMHASLAGKITGMLLEIDNSELLLLLESPESLHSKIEEAVAVLQAHQATEASHKGSTAPFLQ", "length": 632, "header": "tr|A0A8V0ZG78-1|A0A8V0ZG78_CHICK Isoform 1 of Polyadenylate-binding protein OS=Gallus gallus OX=9031 GN=PABPC1L PE=1 SV=1 CANONICAL=A0A8V0ZG78-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG78/entry#A0A8V0ZG78-1", "sequence": { "sequence": 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Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001305364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305364" }, { "database": "PubMed", "id": "22401171", "url": "https://glygen.org/publication/PubMed/22401171" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NLRC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98", "locus": { "chromosome": "11", "start_pos": 647093, "end_pos": 612096, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022005", "url": "https://www.ensembl.org/id/ENSGALG00010022005" } ] } } ], "crossref": [ { "id": "100857413", "url": "https://www.ncbi.nlm.nih.gov/gene/100857413", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857413", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857413", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AQQDETW", "url": "https://omabrowser.org/oma/group/AQQDETW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZG98", "url": "https://www.orthodb.org/?gene=A0A8V0ZG98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNB5", "url": "https://www.orthodb.org/?gene=A0A8V0ZNB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNP9", "url": "https://www.orthodb.org/?gene=A0A8V0ZNP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTY2", "url": "https://www.orthodb.org/?gene=A0A8V0ZTY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47189", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47189", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47189:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47189:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18461", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18461", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9758274", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9758274", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001305364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305364", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZG98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPTLQNDDFNLEGAVASIRPQLVEFLSHRLDWLLSASQHFLPTAVLSGLAGVTDHREKVSVLLDLLEKAGHATWKQFAQCLCMECDLPLEMEILLMSSAGEGNLTQKQEAQTDASDQSSVPRGLTRRRRSSSPISDKGAKQKRLDSAEKYQRLLVDSICKRYGSRRAAGAAAQEPTQPLAFSQAFVNLVLRQSKASRLKERTDKPREDVPSAPEPEECVDTAVRVSDLFGSVVRSGTTKVIFLFGKPGTGKTMLMHRICQKWAEGVLHQFLFTFLFEFRQLNLLKRKLTLKELLFDLFLQPEDSPDAVFQHLLENAQRTLIIFDGLDEFVGNMDVSSASKGSLNRSSSMSISELFAELCHGNLLPGCTVLVTSRPKRVPDFLINTVDLLAEVWGFDHEKVEEYVSHYFRHHSFKEQAIAHLKNNTKLLSMCQIPALCYVVCICLEYLLLKHQTSVELPQTMTQFYIKMLLIFINKQQGEHAGDEEAQLNSNKKAILGLCDLALKGLEAKKLVFYVGDIPEHVKEFASLHGLLTVFEVKTNSAHPETGYAFVHLSLQEFFAALCLMISKSVDKSHLKRKLSLKSKWTLRNEAKTGFMESFHIFLSGLSSKECRTFIMLLAEQSEAWVQDKQDAILQSLKKLAATQLTGPKVIELCHCTFETQGLEVAQHIGSLLNFKYEFKNFRLTPLDMSALVFVINSGQDVTHLDFAGCPLDTDCLEMLASCRNVEHLSFRSRRFGDDFAAALSKGLGEMGSLKKLEVTGGSITAAGLTDMVQALSHCLQLEEINLQDNRIQNPDVKTVMELFSRMEKLKKIDLSKNSLSLNAVLLLAKEFIACQNAAELHVRKDTVIISFSGPSGKVPRSLDLKREQNKECVTPTRHLRLCLQARCLSSQHAKEIVSILQSCPHLSEVDLSDNKLGDEGCSFLLENLSWISISKQLNLSHNLLSVTGIYSLLKAVNTCQRVVEVEVSLYHNTAVLRFTEDGEFASPPASREEPLYPTDDQWDGKENQTPVPSKKIRLTYCRFQASDLEKLCAVLKECGSISELDLSNNYLGDEGLAQLLQFLPNLKTLRSLKLNNNHLSLSSVFCLAQSLCTLEHLETMDLSLGRMQVVHLTFGDRIRLRRTSRWRRSFLVHPKHVTNGQCFRLRNCTVGPEDVTRLCQMLTQCTQLTEIDLCGNALNDQSIERLLSFLPHFCQLTLLSIRNNTFSPCCAVLFANSINLCERIRRVEVRSSQNAFLHLRTSTQSQKTSCRLTDCAIGQRQIEKLCRVLEQHGCLAELDLSRNQLGDEVLRFLLDHLHRVPVTCSLNLSHNRISQRGVLHLINTFTTSGNTTEVQVSLCSKATLIIKMTSRDDPRKILRLTECSFQPEHLEKLCLVLENCTNLTECISSNNNVTVDAAGGLLRSLSKTPGPLKISIEEPWVCKLSVTSLLELAVQAHGNITAIMICKEKNLFQLGVRLPHCLEKVGSVVSRLNLNEPEIKQACFYQRVHDKCTQLQELRWSHVELHDDTEMLVSILLPLPDLKKFELTSCSFTPTGIDCLITGLQRCQAIEELNLGHMKLGDAAIPKLVFGLCEMPSLKRLILNHNSIGDDGCSRLAEALSSMHCMEEINLGHNKIGDLGLINIAAVLLEMQNLKRIDLSGNCPSPAGGEKLMEALANCKHLEELILSRNDFGDGTAVKLALCLPHMNRLKILHLQHNNIGPAGGTELARALMACELLEEISLSENNLGEGGIRALSEGLPRFEHLRKIELRLCGITDDASKLLSRGFQQCPAVEEIILSWNALGDGGAQVLASILPGMETLKMLDLEKNLIGACGATRLAEELVRCPEIQFIRLWDNPVPKGLAESLTSQDPRLCFSFC", "length": 1862, "header": "tr|A0A8V0ZG98-1|A0A8V0ZG98_CHICK Isoform 1 of NLR family CARD domain containing 5 OS=Gallus gallus OX=9031 GN=NLRC5 PE=4 SV=1 CANONICAL=A0A8V0ZG98-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZG98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98/entry#A0A8V0ZG98-1", "sequence": { "sequence": "MQPTLQNDDFNLEGAVASIRPQLVEFLSHRLDWLLSASQHFLPTAVLSGLAGVTDHREKVSVLLDLLEKAGHATWKQFAQCLCMECDLPLEMEILLMSSAGEGNLTQKQEAQTDASDQSSVPRGLTRRRRSSSPISDKGAKQKRLDSAEKYQRLLVDSICKRYGSRRAAGAAAQEPTQPLAFSQAFVNLVLRQSKASRLKERTDKPREDVPSAPEPEECVDTAVRVSDLFGSVVRSGTTKVIFLFGKPGTGKTMLMHRICQKWAEGVLHQFLFTFLFEFRQLNLLKRKLTLKELLFDLFLQPEDSPDAVFQHLLENAQRTLIIFDGLDEFVGNMDVSSASKGSLNRSSSMSISELFAELCHGNLLPGCTVLVTSRPKRVPDFLINTVDLLAEVWGFDHEKVEEYVSHYFRHHSFKEQAIAHLKNNTKLLSMCQIPALCYVVCICLEYLLLKHQTSVELPQTMTQFYIKMLLIFINKQQGEHAGDEEAQLNSNKKAILGLCDLALKGLEAKKLVFYVGDIPEHVKEFASLHGLLTVFEVKTNSAHPETGYAFVHLSLQEFFAALCLMISKSVDKSHLKRKLSLKSKWTLRNEAKTGFMESFHIFLSGLSSKECRTFIMLLAEQSEAWVQDKQDAILQSLKKLAATQLTGPKVIELCHCTFETQGLEVAQHIGSLLNFKYEFKNFRLTPLDMSALVFVINSGQDVTHLDFAGCPLDTDCLEMLASCRNVEHLSFRSRRFGDDFAAALSKGLGEMGSLKKLEVTGGSITAAGLTDMVQALSHCLQLEEINLQDNRIQNPDVKTVMELFSRMEKLKKIDLSKNSLSLNAVLLLAKEFIACQNAAELHVRKDTVIISFSGPSGKVPRSLDLKREQNKECVTPTRHLRLCLQARCLSSQHAKEIVSILQSCPHLSEVDLSDNKLGDEGCSFLLENLSWISISKQLNLSHNLLSVTGIYSLLKAVNTCQRVVEVEVSLYHNTAVLRFTEDGEFASPPASREEPLYPTDDQWDGKENQTPVPSKKIRLTYCRFQASDLEKLCAVLKECGSISELDLSNNYLGDEGLAQLLQFLPNLKTLRSLKLNNNHLSLSSVFCLAQSLCTLEHLETMDLSLGRMQVVHLTFGDRIRLRRTSRWRRSFLVHPKHVTNGQCFRLRNCTVGPEDVTRLCQMLTQCTQLTEIDLCGNALNDQSIERLLSFLPHFCQLTLLSIRNNTFSPCCAVLFANSINLCERIRRVEVRSSQNAFLHLRTSTQSQKTSCRLTDCAIGQRQIEKLCRVLEQHGCLAELDLSRNQLGDEVLRFLLDHLHRVPVTCSLNLSHNRISQRGVLHLINTFTTSGNTTEVQVSLCSKATLIIKMTSRDDPRKILRLTECSFQPEHLEKLCLVLENCTNLTECISSNNNVTVDAAGGLLRSLSKTPGPLKISIEEPWVCKLSVTSLLELAVQAHGNITAIMICKEKNLFQLGVRLPHCLEKVGSVVSRLNLNEPEIKQACFYQRVHDKCTQLQELRWSHVELHDDTEMLVSILLPLPDLKKFELTSCSFTPTGIDCLITGLQRCQAIEELNLGHMKLGDAAIPKLVFGLCEMPSLKRLILNHNSIGDDGCSRLAEALSSMHCMEEINLGHNKIGDLGLINIAAVLLEMQNLKRIDLSGNCPSPAGGEKLMEALANCKHLEELILSRNDFGDGTAVKLALCLPHMNRLKILHLQHNNIGPAGGTELARALMACELLEEISLSENNLGEGGIRALSEGLPRFEHLRKIELRLCGITDDASKLLSRGFQQCPAVEEIILSWNALGDGGAQVLASILPGMETLKMLDLEKNLIGACGATRLAEELVRCPEIQFIRLWDNPVPKGLAESLTSQDPRLCFSFC", "length": 1862, "header": "tr|A0A8V0ZG98-1|A0A8V0ZG98_CHICK Isoform 1 of NLR family CARD domain containing 5 OS=Gallus gallus OX=9031 GN=NLRC5 PE=4 SV=1 CANONICAL=A0A8V0ZG98-1" }, "locus": { "chromosome": "11", "start_pos": 645953, "end_pos": 614354, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053683.1", "url": "https://www.ensembl.org/id/ENSGALT00010053683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032336.1", "url": "https://www.ensembl.org/id/ENSGALP00010032336.1" } ] } }, { "isoform_ac": "A0A8V0ZNB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98/entry#A0A8V0ZNB5-1", "sequence": { "sequence": "MCFCLHGNLTQKQEAQTDASDQSSVPRGLTRRRRSSSPISDKGAKQKRLDSAEKYQRLLVDSICKRYGSRRAAGAAAQEPTQPLAFSQAFVNLVLRQSKASRLKERTDKPREDVPSAPEPEECVDTAVRVSDLFGSVVRSGTTKVIFLFGKPGTGKTMLMHRICQKWAEGVLHQFLFTFLFEFRQLNLLKRKLTLKELLFDLFLQPEDSPDAVFQHLLENAQRTLIIFDGLDEFVGNMDVSSASKGSLNRSSSMSISELFAELCHGNLLPGCTVLVTSRPKRVPDFLINTVDLLAEVWGFDHEKVEEYVSHYFRHHSFKEQAIAHLKNNTKLLSMCQIPALCYVVCICLEYLLLKHQTSVELPQTMTQFYIKMLLIFINKQQGEHAGDEEAQLNSNKKAILGLCDLALKGLEAKKLVFYVGDIPEHVKEFASLHGLLTVFEVKTNSAHPETGYAFVHLSLQEFFAALCLMISKSVDKSHLKRKLSLKSKWTLRNEAKTGFMESFHIFLSGLSSKECRTFIMLLAEQSEAWVQDKQDAILQSLKKLAATQLTGPKVIELCHCTFETQGLEVAQHIGSLLNFKYEFKNFRLTPLDMSALVFVINSGQDVTHLDFAGCPLDTDCLEMLASCRNVEHLSFRSRRFGDDFAAALSKGLGEMGSLKKLEVTGGSITAAGLTDMVQALSHCLQLEEINLQDNRIQNPDVKTVMELFSRMEKLKKIDLSKNSLSLNAVLLLAKEFIACQNAAELHVRKDTVIISFSGPSGKVPRSLDLKREQNKECVTPTRHLRLCLQARCLSSQHAKEIVSILQSCPHLSEVDLSDNKLGDEGCSFLLENLSWISISKQLNLSHNLLSVTGIYSLLKAVNTCQRVVEVEVSLYHNTAVLRFTEDGEFASPPASREEPLYPTDDQWDGKENQTPVPSKKIRLTYCRFQASDLEKLCAVLKECGSISELDLSNNYLGDEGLAQLLQFLPNLKTLRSLKLNNNHLSLSSVFCLAQSLCTLEHLETMDLSLGRMQVVHLTFGDRIRLRRTSRWRRSFLVHPKHVTNGQCFRLRNCTVGPEDVTRLCQMLTQCTQLTEIDLCGNALNDQSIERLLSFLPHFCQLTLLSIRNNTFSPCCAVLFANSINLCERIRRVEVRSSQNAFLHLRTSTQSQKTSCRLTDCAIGQRQIEKLCRVLEQHGCLAELDLSRNQLGDEVLRFLLDHLHRVPVTCSLNLSHNRISQRGVLHLINTFTTSGNTTEVQVSLCSKATLIIKMTSRDDPRKILRLTECSFQPEHLEKLCLVLENCTNLTECISSNNNVTVDAAGGLLRSLSKTPGPLKISIEEPWVCKLSVTSLLELAVQAHGNITAIMICKEKNLFQLGVRLPHCLEKVGSVVSRLNLNEPEIKQACFYQRVHDKCTQLQELRWSHVELHDDTEMLVSILLPLPDLKKFELTSCSFTPTGIDCLITGLQRCQAIEELNLGHMKLGDAAIPKLVFGLCEMPSLKRLILNHNSIGDDGCSRLAEALSSMHCMEEINLGHNKIGDLGLINIAAVLLEMQNLKRIDLSGNCPSPAGGEKLMEALANCKHLEELILSRNDFGDGTAVKLALCLPHMNRLKILHLQHNNIGPAGGTELARALMACELLEEISLSENNLGEGGIRALSEGLPRFEHLRKIELRLCGITDDASKLLSRGFQQCPAVEEIILSWNALGDGGAQVLASILPGMETLKMLDLEKNLIGACGATRLAEELVRCPEIQFIRLWDNPVPKGLAESLTSQDPRLCFSFC", "length": 1766, "header": "tr|A0A8V0ZNB5-1|A0A8V0ZNB5_CHICK Computationally mapped isoform of NLR family CARD domain containing 5 OS=Gallus gallus OX=9031 GN=NLRC5 PE=4 SV=1 CANONICAL=A0A8V0ZG98-1" }, "locus": { "chromosome": "11", "start_pos": 645953, "end_pos": 616727, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053633.1", "url": "https://www.ensembl.org/id/ENSGALT00010053633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032310.1", "url": "https://www.ensembl.org/id/ENSGALP00010032310.1" } ] } }, { "isoform_ac": "A0A8V0ZNP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98/entry#A0A8V0ZNP9-1", "sequence": { "sequence": "MSSRSSFPTLQNDDFNLEGAVASIRPQLVEFLSHRLDWLLSASQHFLPTAVLSGLAGVTDHREKVSVLLDLLEKAGHATWKQFAQCLCMECDLPLEMEILLMSSAGEGNLTQKQEAQTDASDQSSVPRGLTRRRRSSSPISDKGAKQKRLDSAEKYQRLLVDSICKRYGSRRAAGAAAQEPTQPLAFSQAFVNLVLRQSKASRLKERTDKPREDVPSAPEPEECVDTAVRVSDLFGSVVRSGTTKVIFLFGKPGTGKTMLMHRICQKWAEGVLHQFLFTFLFEFRQLNLLKRKLTLKELLFDLFLQPEDSPDAVFQHLLENAQRTLIIFDGLDEFVGNMDVSSASKGSLNRSSSMSISELFAELCHGNLLPGCTVLVTSRPKRVPDFLINTVDLLAEVWGFDHEKVEEYVSHYFRHHSFKEQAIAHLKNNTKLLSMCQIPALCYVVCICLEYLLLKHQTSVELPQTMTQFYIKMLLIFINKQQGEHAGDEEAQLNSNKKAILGLCDLALKGLEAKKLVFYVGDIPEHVKEFASLHGLLTVFEVKTNSAHPETGYAFVHLSLQEFFAALCLMISKSVDKSHLKRKLSLKSKWTLRNEAKTGFMESFHIFLSGLSSKECRTFIMLLAEQSEAWVQDKQDAILQSLKKLAATQLTGPKVIELCHCTFETQGLEVAQHIGSLLNFKYEFKNFRLTPLDMSALVFVINSGQDVTHLDFAGCPLDTDCLEMLASCRNVEHLSFRSRRFGDDFAAALSKGLGEMGSLKKLEVTGGSITAAGLTDMVQALSHCLQLEEINLQDNRIQNPDVKTVMELFSRMEKLKKIDLSKNSLSLNAVLLLAKEFIACQNAAELHVRKDTVIISFSGPSGKVPRSLDLKREQNKECVTPTRHLRLCLQARCLSSQHAKEIVSILQSCPHLSEVDLSDNKLGDEGCSFLLENLSWISISKQLNLSHNLLSVTGIYSLLKAVNTCQRVVEVEVSLYHNTAVLRFTEDGEFASPPASREEPLYPTDDQWDGKENQTPVPSKKIRLTYCRFQASDLEKLCAVLKECGSISELDLSNNYLGDEGLAQLLQFLPNLKTLRSLKLNNNHLSLSSVFCLAQSLCTLEHLETMDLRYDQENCSFPRLRRTSRWRRSFLVHPKHVTNGQCFRLRNCTVGPEDVTRLCQMLTQCTQLTEIDLCGNALNDQSIERLLSFLPHFCQLTLLSIRNNTFSPCCAVLFANSINLCERIRRVEVRSSQNAFLHLRTSTQSQKTSCRLTDCAIGQRQIEKLCRVLEQHGCLAELDLSRNQLGDEVLRFLLDHLHRVPVTCSLNLSHNRISQRGVLHLINTFTTSGNTTEVQVSLCSKATLIIKMTSRDDPRKILRLTECSFQPEHLEKLCLVLENCTNLTECISSNNNVTVDAAGGLLRSLSKTPGPLKISIEEPWVCKLSVTSLLELAVQAHGNITAIMICKEKNLFQLGVRLPHCLEKVGSVVSRLNLNEPEIKQACFYQRVHDKCTQLQELRWSHVELHDDTEMLVSILLPLPDLKKFELTSCSFTPTGIDCLITGLQRCQAIEELNLGHMKLGDAAIPKLVFGLCEMPSLKRLILNHNSIGDDGCSRLAEALSSMHCMEEINLGHNKIGDLGLINIAAVLLEMQNLKRIDLSGNCPSPAGGEKLMEALANCKHLEELILSRNDFGDGTAVKLALCLPHMNRLKILHLQHNNIGPAGGTELARALMACELLEEISLSENNLGEGGIRALSEGLPRFEHLRKIELRLCGITDDASKLLSRGFQQCPAVEEIILSWNALGDGGAQVLASILPGMETLKMLDLEKNLIGACGATRLAEELVRCPEIQFIRLWDNPVPKGLAESLTSQDPRLCFSFC", "length": 1861, "header": "tr|A0A8V0ZNP9-1|A0A8V0ZNP9_CHICK Computationally mapped isoform of NLR family CARD domain containing 5 OS=Gallus gallus OX=9031 GN=NLRC5 PE=4 SV=1 CANONICAL=A0A8V0ZG98-1" }, "locus": { "chromosome": "11", "start_pos": 645953, "end_pos": 614455, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053647.1", "url": "https://www.ensembl.org/id/ENSGALT00010053647.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032314.1", "url": "https://www.ensembl.org/id/ENSGALP00010032314.1" } ] } }, { "isoform_ac": "A0A8V0ZTY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98/entry#A0A8V0ZTY2-1", "sequence": { "sequence": "MCHRNLTQKQEAQTDASDQSSVPRGLTRRRRSSSPISDKGAKQKRLDSAEKYQRLLVDSICKRYGSRRAAGAAAQEPTQPLAFSQAFVNLVLRQSKASRLKERTDKPREDVPSAPEPEECVDTAVRVSDLFGSVVRSGTTKVIFLFGKPGTGKTMLMHRICQKWAEGVLHQFLFTFLFEFRQLNLLKRKLTLKELLFDLFLQPEDSPDAVFQHLLENAQRTLIIFDGLDEFVGNMDVSSASKGSLNRSSSMSISELFAELCHGNLLPGCTVLVTSRPKRVPDFLINTVDLLAEVWGFDHEKVEEYVSHYFRHHSFKEQAIAHLKNNTKLLSMCQIPALCYVVCICLEYLLLKHQTSVELPQTMTQFYIKMLLIFINKQQGEHAGDEEAQLNSNKKAILGLCDLALKGLEAKKLVFYVGDIPEHVKEFASLHGLLTVFEVKTNSAHPETGYAFVHLSLQEFFAALCLMISKSVDKSHLKRKLSLKSKWTLRNEAKTGFMESFHIFLSGLSSKECRTFIMLLAEQSEAWVQDKQDAILQSLKKLAATQLTGPKVIELCHCTFETQGLEVAQHIGSLLNFKYEFKNFRLTPLDMSALVFVINSGQDVTHLDFAGCPLDTDCLEMLASCRNVEHLSFRSRRFGDDFAAALSKGLGEMGSLKKLEVTGGSITAAGLTDMVQALSHCLQLEEINLQDNRIQNPDVKTVMELFSRMEKLKKIDLSKNSLSLNAVLLLAKEFIACQNAAELHVRKDTVIISFSGPSGKVPRSLDLKREQNKECVTPTRHLRLCLQARCLSSQHAKEIVSILQSCPHLSEVDLSDNKLGDEGCSFLLENLSWISISKQLNLSHNLLSVTGIYSLLKAVNTCQRVVEVEVSLYHNTAVLRFTEDGEFASPPASREEPLYPTDDQWDGKENQTPVPSKKIRLTYCRFQASDLEKLCAVLKECGSISELDLSNNYLGDEGLAQLLQFLPNLKTLRSLKLNNNHLSLSSVFCLAQSLCTLEHLETMDLSLGRMQVVHLTFGDRIRLRRTSRWRRSFLVHPKHVTNGQCFRLRNCTVGPEDVTRLCQMLTQCTQLTEIDLCGNALNDQSIERLLSFLPHFCQLTLLSIRNNTFSPCCAVLFANSINLCERIRRVEVRSSQNAFLHLRTSTQSQKTSCRLTDCAIGQRQIEKLCRVLEQHGCLAELDLSRNQLGDEVLRFLLDHLHRVPVTCSLNLSHNRISQRGVLHLINTFTTSGNTTEVQVSLCSKATLIIKMTSRDDPRKILRLTECSFQPEHLEKLCLVLENCTNLTECISSNNNVTVDAAGGLLRSLSKTPGPLKISIEEPWVCKLSVTSLLELAVQAHGNITAIMICKEKNLFQLGVRLPHCLEKVGSVVSRLNLNEPEIKQACFYQRVHDKCTQLQELRWSHVELHDDTEMLVSILLPLPDLKKFELTSCSFTPTGIDCLITGLQRCQAIEELNLGHMKLGDAAIPKLVFGLCEMPSLKRLILNHNSIGDDGCSRLAEALSSMHCMEEINLGHNKIGDLGLINIAAVLLEMQNLKRIDLSGNCPSPAGGEKLMEALANCKHLEELILSRNDFGDGTAVKLALCLPHMNRLKILHLQHNNIGPAGGTELARALMACELLEEISLSENNLGEGGIRALSEGLPRFEHLRKIELRLCGITDDASKLLSRGFQQCPAVEEIILSWNALGDGGAQVLASILPGMETLKMLDLEKNLIGACGATRLAEELVRCPEIQFIRLWDNPVPKGLAESLTSQDPRLCFSFC", "length": 1763, "header": "tr|A0A8V0ZTY2-1|A0A8V0ZG98_CHICK Computationally mapped isoform of NLR family CARD domain containing 5 OS=Gallus gallus OX=9031 GN=NLRC5 PE=4 SV=1 CANONICAL=A0A8V0ZG98-1" }, "locus": { "chromosome": "11", "start_pos": 645953, "end_pos": 617308, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053617.1", "url": "https://www.ensembl.org/id/ENSGALT00010053617.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032302.1", "url": "https://www.ensembl.org/id/ENSGALP00010032302.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "NLRC5 knockdown in chicken macrophages alters response to LPS and poly (I:C) stimulation.", "journal": "BMC veterinary research", "date": "2012-03-08", "authors": "Lian Ling, Ciraci Ceren, Chang Guobin, Hu Jingdong, Lamont Susan J", "evidence": [ { "database": "RefSeq", "id": "NP_001305364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305364" } ], "reference": [ { "type": "PubMed", "id": "22401171", "url": "https://glygen.org/publication/PubMed/22401171" } ] }, { "title": "A mutation in the NLRC5 promoter limits NF-\u03baB signaling after Salmonella Enteritidis infection in the spleen of young chickens.", "journal": "Gene", "date": "2015-09-01", "authors": "Chang Guobin, Liu Xiangping, Ma Teng, Xu Lu, Wang Hongzhi, Li Zhiteng, Guo Xiaomin, Xu Qi, Chen Guohong", "evidence": [ { "database": "RefSeq", "id": "NP_001305364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305364" } ], "reference": [ { "type": "PubMed", "id": "25979675", "url": "https://glygen.org/publication/PubMed/25979675" } ] }, { "title": "Characterization of the NLRC5 promoter in chicken: SNPs, regulatory elements and CpG islands.", "journal": "Animal genetics", "date": "2016-10", "authors": "Guo X M, Liu X P, Chang G B, Xu L, Bi Y L, Wang H Z, Zhang Y, Zhu P F, Wu Y, Chen G H", "evidence": [ { "database": "RefSeq", "id": "NP_001305364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305364" } ], "reference": [ { "type": "PubMed", "id": "27429394", "url": "https://glygen.org/publication/PubMed/27429394" } ] }, { "title": "Expression patterns of NLRC5 and key genes in the STAT1 pathway following infection with Salmonella pullorum.", "journal": "Gene", "date": "2017-01-15", "authors": "Qiu Lingling, Ma Teng, Chang Guobin, Liu Xiangping, Guo Xiaomin, Xu Lu, Zhang Yang, Zhao Wenming, Xu Qi, Chen Guohong", "evidence": [ { "database": "RefSeq", "id": "NP_001305364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305364" } ], "reference": [ { "type": "PubMed", "id": "27771450", "url": "https://glygen.org/publication/PubMed/27771450" } ] }, { "title": "NLRC5 Serves as a Pro-viral Factor During Influenza Virus Infection in Chicken Macrophages.", "journal": "Frontiers in cellular and infection microbiology", "date": "2020", "authors": "Chothe Shubhada K, Nissly Ruth H, Lim Levina, Bhushan Gitanjali, Bird Ian, Radzio-Basu Jessica, Jayarao Bhushan M, Kuchipudi Suresh V", "evidence": [ { "database": "RefSeq", "id": "NP_001305364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001305364" } ], "reference": [ { "type": "PubMed", "id": "32509599", "url": "https://glygen.org/publication/PubMed/32509599" } ] } ], "pathway": [ { "id": "gga:100857413", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857413", "resource": "KEGG Pathway" }, { "id": "R-GGA-9758274", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9758274", "resource": "Reactome", "description": "Regulation of NF-kappa B signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M751-1", "protein_name": "Protein NLRC5", "gene_name": "Nlrc5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAESYRLGNENLWAWLVELLSKKPEWLSAKVRFFLPTLDPDCSNEAPISEVTHHQLNRLFAQGPATWESFIYTLCIELEVPLSLEVPLLSIWGQKDEFSKQLGACEESHPGPELHHGVKRPFQSYGSSPRRKHSRKQQLELVKKYLKLLRTSAQQCHGGQCPGAWNARDSPQTYIPPIVQWSGTSAPLDAQEGARIGGDPEAADSTDVSIHDLFNFKAHKGPRVTVVLGKAGMGKTTLAHRLHWRWAHGQLDRFQAVFLLEFRQLNMITQLLTLPQLLFDLYLSPESDDADAVWQYLEENAHQILLIFDGLDEALHTDSVGTDNAGSALTLFSELCHGDLLPGCWVMTTSRPGKLPSCVPTEAAMVYMWGFDGLRVEKYVTHFFSDLLSQELALKEMRANERLRGMCAIPALCRVACFCLRCSLLSGSSPGQSSALLPTITQLYLQMVKTFSSSGTLSATSLLGLGNVALRGLVTGKVIFSVEDIPPQLMALGAVHSLLTSFCIRTRSGHKEIGYAFVHLNLQEFFAALYLMASDTVDKDTLINYVTLNSHWVLRTKAKPGLSDHLPTFLAGLASHTCHTFLCHLAQQDEAWVGSRQATVIQVLRKLASRKLTGPKMVELYHYVAETQDLELARFVAQSLPFDLSFHNFPLTRADLASLANILEHRDGPIHLDFDGCPLEPHCPEALVGCGQVENLSFKSRKCGDAFAEALCRSLPTMGSLKMLGLTGSKITAQGISHLIQALPLCSQLEEVSLHDNQLKDPEVLSLVDLIPCLRKLQKLDLSQNSFCMSTLLSSVKAAITCPTVRKLQVRESELIFFLSPVPETATQQSGASDAQGEDSPKEGQSRNLQLRLQKCQLRVHDAKALVELFQKGPRLEEVDLSGNHLKDEGCRLVTKAVSQLHIAQKLDLSDNGLSQTGVTYLLKAVSTCGTLEELHISLLTNTVVLTFAQELRDQEGSFKRGAQLTGFMSPVTSELSQRSRRIRLTHCGFLAEHTEKLCEALRVSCQSHPLDHLDLSDNFLKDKGVILLTQLLPRLGPLKSLNLSRNDFSMDAVFSLVLCMSSLQWLFHLEVSLESDCIFLRGAGTSRDALAGGPEFPAGAQLLELSQRCTSRSFCLQECQLESLNLAYLCDALEKCPGPLEIQLSCKSLNDDSLKTLLQRLPQIPQLSQLRLTHTVLSSRSPFLLADIFNLCPWVQKVNLRSLSHAVLHFNSNEEHEAVCCGFPGCSLKQEHMETLCCALSKCKAISQLDLTDNLLDDSGLRCLLGYLPQLPISGWLDLSHNSISQEGVLYLLETLPSYPHIQEVSVSLGTKQIFRMHFSKEEGTGTILRLCECSFSTEQVSRLTSNLSHQQLTELWLTKCGLDPPQLTTLLNLVNRPAGLLDLRLEEPWVGYAGLPALMEVCAQASGCLTELSISESQEKLWLQLEFPRQEDHSEAMALRLAHCDLGTDHGLLMRQLVETCARLQQLSLSQVSFSDDDGTRSRLLQNILISSCELKSFRLTFSNVSTESPAHLASGLEHCHHLEELDFSNNSLCKEDTELLIGALQRTCRLKRLHLSHLPLETSSLDLLVQGLSNMTLLQDLCLKHSQIGDMGTQHLAAILPRLPGLRKLDLSGNRIGPAGGMQLVKSLTHFKNLEEIILGNNTLGDPTALELAQRFPPQLRVLCLTSSHLGPEGALCLAQALEQCPHIEEVSLAENNLAGGVPHFSKRLPLLKQINLVSCKIEDQAAKHLATNLTLCPALEKLLLSWNHLGDEMAAELAQVLPQMGQLKRVDLEKNQITACGAQLLAQGLVHGSCVPVIRLWNNPIPACVAQSLQSQEPRLDFSFFEQQPQTL", "length": 1837 }, "evidence": [ { "id": "A0A8V0ZG98", "url": "https://omabrowser.org/oma/group/A0A8V0ZG98/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C3VPR6-1", "protein_name": "Protein NLRC5", "gene_name": "Nlrc5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDAESIRLNNENLWAWLVRLLSKNPEWLSAKLRSFLPTMDLDCSYEPSNPEVIHRQLNRLFAQGMATWKSFINDLCFELDVPLDMEIPLVSIWGPRDEFSKQLGAGEESCPGPQLYHGAKRPFQSYGSSPRRKNSKKQQLELAKKYLKLLKTSAQQWHGGVCPGAWLTPHSPQTYIPPVLQWSRATAPLDAQEGATLGDPEAADNIDVSIQDLFSFKAHKGPRVTVLLGKAGMGKTTLAYRLRWRWAQGQLDRFQALFLFEFRQLNMITQLPTLPQLLFDLYLMPESEPDAVFQYLKENAQEVLLIFDGLDEALHADSVGTDNAGSALTLFSELCHGNLLPGCWVMTTSRPGKLPSCVPTEAATVHMWGFDGLRVEKYVTCFFSDLLSQELALKEMRTNARLRGMCAIPALCTVTCFCLRRLLPGSSPGQSAALLPTITQLYLQMVETFSPSETLLDTSILGFGKVALRGLDTGKVVFSVEDISPQLMSFGAVHSLLTSFCIHTRPGHEEIGYAFVHLSLQEFFAALYLMASHTVDKDTLVEYVTLNSHWVLRTKGRLGLSDHLPAFLAGLASHTCHMFLCQLAQQDRAWVGSRQAAVIQVLRKLASRKLTGPKMIELYHCVAETQDLELARFTAQSLPSRLSFHNFPLTHADLAALANILEHRDDPIHLDFDGCPLEPHCPEALVGCGQVENLSFKSRKCGDAFAEALCRSLPTMGSLKTLGLTGSRITAQGISHLIQTLPLCSQLEEVSLHDNQLKDPEVLSLVELLPSLPKLQKLDLSRNSFSRSILLSLVKVAITCPTVRKLQVRELDLIFYLSPVTETATQQSGASDVQGKDSLKEGQSRSLQLRLQKCQLRIRDAEALVELFQKSPQLEEVNLSGNHLEDDGCRLVAEAASQLHIAQKLDLSDNGLSQTGVTYVLKAMSTCGTLEDLHISLLNNTVVLTFAQEPREQEGSCKGRAPLISFVSPVTSELSQRSRRIRLTHCGFLAKHTETLCEALRASCQTHNLDHLDLSDNSLGGKGVILLTELLPGLGPLKSLNLSRNGLSMDAVFSLVQCLSSLQWVFHLDVSLESDCIFLRGAGTSRDALEPKFQTGVQVLELSQRYTSRSFCLQECQLEPTSLTFLCATLEKSPGPLEVQLSCKSLSDDSLKILLQCLPQLPQLSLLQLRHTVLSSRSPFLLADIFNLCPRVRKVTLRSLCHAVLHFDSNEEQEGVCCGFPGCSLSQEHMETLCCALSKCNALSQLDLTDNLLGDIGLRCLLECLPQLPISGWLDLSHNNISQEGILYLLETLPSYPNIQEVSVSLSSEQIFRMCFSKKEGAGTSLRLCECSFSPEQVSKLASSLSQAQQLTELWLTKCHLDLPQLTMLLNLVNRPTGLLGLRLEEPWVDSVSLPALMEVCAQASGCLTELSISEIQRKLWLQLEFPHQEGNSDSMALRLAHCDLETEHSHLMIQLVETYARLQQLSLSQVSFNDNDGTSSKLLQNILLSSCELKSFRLTFSQVSTKSLTHLAFGLGHCHHLEELDFSNNSLREEDTELLMGALQGTCRLKKLHLSFLPLGASSLALLIQGLSRMTLLQDLCLSHNQIGDVGTQCLAAILPKLPELRKFDLSHNQIGDVGTQCLAAILPKLPELRKFNLSHNQIGHVGTQCLAAILPKLPELRKFDLSRNQIGDVGTQCLAAILPKLPELRKFDLSGNRIGPAGGVQLVKSLTHFEHLEEIKLGNNALGEPTALELAQRLPPQLRVLCLPSSHLGPEGALGLAQALEQCPHIEEVSLAENNLAGGVPRFSKRLPLLRQIDLEFCKIEDQAARHLAANLTLFPALEKLLLSGNLLGDEVAAELAQVLPQMGQLKKVNLEWNRITARGAQLLAQGLVQGSCVPVIRLWNNPILNDVAQSLQSQEPRLDFSITDQQTL", "length": 1915 }, "evidence": [ { "id": "A0A8V0ZG98", "url": "https://omabrowser.org/oma/group/A0A8V0ZG98/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86WI3-1", "protein_name": "Protein NLRC5", "gene_name": "NLRC5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVGLQLGNKNLWSCLVRLLTKDPEWLNAKMKFFLPNTDLDSRNETLDPEQRVILQLNKLHVQGSDTWQSFIHCVCMQLEVPLDLEVLLLSTFGYDDGFTSQLGAEGKSQPESQLHHGLKRPHQSCGSSPRRKQCKKQQLELAKKYLQLLRTSAQQRYRSQIPGSGQPHAFHQVYVPPILRRATASLDTPEGAIMGDVKVEDGADVSISDLFNTRVNKGPRVTVLLGKAGMGKTTLAHRLCQKWAEGHLNCFQALFLFEFRQLNLITRFLTPSELLFDLYLSPESDHDTVFQYLEKNADQVLLIFDGLDEALQPMGPDGPGPVLTLFSHLCNGTLLPGCRVMATSRPGKLPACLPAEAAMVHMLGFDGPRVEEYVNHFFSAQPSREGALVELQTNGRLRSLCAVPALCQVACLCLHHLLPDHAPGQSVALLPNMTQLYMQMVLALSPPGHLPTSSLLDLGEVALRGLETGKVIFYAKDIAPPLIAFGATHSLLTSFCVCTGPGHQQTGYAFTHLSLQEFLAALHLMASPKVNKDTLTQYVTLHSRWVQRTKARLGLSDHLPTFLAGLASCTCRPFLSHLAQGNEDCVGAKQAAVVQVLKKLATRKLTGPKVVELCHCVDETQEPELASLTAQSLPYQLPFHNFPLTCTDLATLTNILEHREAPIHLDFDGCPLEPHCPEALVGCGQIENLSFKSRKCGDAFAEALSRSLPTMGRLQMLGLAGSKITARGISHLVKALPLCPQLKEVSFRDNQLSDQVVLNIVEVLPHLPRLRKLDLSSNSICVSTLLCLARVAVTCPTVRMLQAREADLIFLLSPPTETTAELQRAPDLQESDGQRKGAQSRSLTLRLQKCQLQVHDAEALIALLQEGPHLEEVDLSGNQLEDEGCRLMAEAASQLHIARKLDLSNNGLSVAGVHCVLRAVSACWTLAELHISLQHKTVIFMFAQEPEEQKGPQERAAFLDSLMLQMPSELPLSSRRMRLTHCGLQEKHLEQLCKALGGSCHLGHLHLDFSGNALGDEGAARLAQLLPGLGALQSLNLSENGLSLDAVLGLVRCFSTLQWLFRLDISFESQHILLRGDKTSRDMWATGSLPDFPAAAKFLGFRQRCIPRSLCLSECPLEPPSLTRLCATLKDCPGPLELQLSCEFLSDQSLETLLDCLPQLPQLSLLQLSQTGLSPKSPFLLANTLSLCPRVKKVDLRSLHHATLHFRSNEEEEGVCCGRFTGCSLSQEHVESLCWLLSKCKDLSQVDLSANLLGDSGLRCLLECLPQVPISGLLDLSHNSISQESALYLLETLPSCPRVREASVNLGSEQSFRIHFSREDQAGKTLRLSECSFRPEHVSRLATGLSKSLQLTELTLTQCCLGQKQLAILLSLVGRPAGLFSLRVQEPWADRARVLSLLEVCAQASGSVTEISISETQQQLCVQLEFPRQEENPEAVALRLAHCDLGAHHSLLVGQLMETCARLQQLSLSQVNLCEDDDASSLLLQSLLLSLSELKTFRLTSSCVSTEGLAHLASGLGHCHHLEELDLSNNQFDEEGTKALMRALEGKWMLKRLDLSHLLLNSSTLALLTHRLSQMTCLQSLRLNRNSIGDVGCCHLSEALRAATSLEELDLSHNQIGDAGVQHLATILPGLPELRKIDLSGNSISSAGGVQLAESLVLCRRLEELMLGCNALGDPTALGLAQELPQHLRVLHLPFSHLGPGGALSLAQALDGSPHLEEISLAENNLAGGVLRFCMELPLLRQIDLVSCKIDNQTAKLLTSSFTSCPALEVILLSWNLLGDEAAAELAQVLPQMGRLKRVDLEKNQITALGAWLLAEGLAQGSSIQVIRLWNNPIPCDMAQHLKSQEPRLDFAFFDNQPQAPWGT", "length": 1866 }, "evidence": [ { "id": "A0A8V0ZG98", "url": "https://omabrowser.org/oma/group/A0A8V0ZG98/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZG98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZG98" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZGA5" } ], "pmid": "" }, { "name": "positive regulation of neuron apoptotic process", "id": "GO:0043525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGA5" } ], "pmid": "" }, { "name": "cellular response to UV", "id": "GO:0034644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034644", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGA5" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGA5" } ], "pmid": "" }, { "name": "positive regulation of execution phase of apoptosis", "id": "GO:1900119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900119", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGA5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGA5" } ], "pmid": "" }, { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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}, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "uniprot_ac": "A0A8V0ZGC1", "uniprot_id": "A0A8V0ZGC1_CHICK", "mass": { "chemical_mass": 24064.0, "monoisotopic_mass": 24064.0 }, "refseq": { "ac": "XP_025005900", "name": "T-cell surface glycoprotein CD8 alpha chain-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005900" }, "gene_names": [ { "name": "LOC124416945", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC1" } ] }, { "name": "LOC124416945", "type": "synonym", "evidence": [ { "id": "XP_025005900", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005900" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC1/entry#names_and_taxonomy" } ] }, { "name": "T-cell surface glycoprotein CD8 alpha chain-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025005900", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005900" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025005900.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025005900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005900" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC124416945", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC1", "locus": {} } ], "crossref": [ { "id": "124416945", "url": "https://www.ncbi.nlm.nih.gov/gene/124416945", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015468", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015468", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGC1", "url": "https://www.orthodb.org/?gene=A0A8V0ZGC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10441:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10441:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025005900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005900", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220, "header": "tr|A0A8V0ZGC1-1|A0A8V0ZGC1_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC124416945 PE=4 SV=1 CANONICAL=A0A8V0ZGC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC1/entry#A0A8V0ZGC1-1", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220, "header": "tr|A0A8V0ZGC1-1|A0A8V0ZGC1_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC124416945 PE=4 SV=1 CANONICAL=A0A8V0ZGC1-1" }, "locus": { "chromosome": "4", "start_pos": 85517303, "end_pos": 85507164, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046379.1", "url": "https://www.ensembl.org/id/ENSGALT00010046379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027614.1", "url": "https://www.ensembl.org/id/ENSGALP00010027614.1" } ] } } ], "glycosylation": [], 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"database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WVZ0-1", "protein_name": "2.7.1.138", "gene_name": "cerk", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A0A8V0ZGC1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGC1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC1" } ], "pmid": "" }, { "name": "T cell mediated immunity", "id": "GO:0002456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC1" } ], "pmid": "" }, { "name": "cytotoxic T cell differentiation", "id": "GO:0045065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045065", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"MISSSPWKSNAPGPSAGSMPACPRATPRRHSHHFRRSAPPRPIPTRVFTYAPPLPPTRREVSAPRGALWEMQFFIPSLRRHPPAAPARRTTPPGMQRGRGSPARPSMAAALGGLRGKGGQGAGSGSGVPRRDSPRPTVPYRPQSLGCTRRTRAAPEATSISAKLRPLPVDPAHLLATPPGLGRGRGWSWGRGRVGAAGSSLAPPPESSLPTGFLAAAGRGAQGRQSCHRPAGPPVPPRPREPAGQLPEGVEYIPTRKKGKNPMKPVGVAWAIGLPSAIILFLLVKREVDKNRLEQLHIRRKMLGANVGDYETERYRRDA", "length": 319, "header": "tr|A0A8V0ZGD1-1|A0A8V0ZGD1_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZGD1-1" }, "locus": { "chromosome": "7", "start_pos": 22189219, "end_pos": 22188176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046395.1", "url": "https://www.ensembl.org/id/ENSGALT00010046395.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027624.1", "url": "https://www.ensembl.org/id/ENSGALP00010027624.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGE0-1", "uniprot_ac": "A0A8V0ZGE0", "uniprot_id": "A0A8V0ZGE0_CHICK", "mass": { "chemical_mass": 52343.0, "monoisotopic_mass": 52343.0 }, "refseq": {}, "gene_names": [ { "name": "VCPKMT", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE0" } ] } ], "protein_names": [ { "name": "Valosin containing protein lysine methyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VCPKMT", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE0", "locus": { "chromosome": "5", "start_pos": 57476120, "end_pos": 57480357, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019209", "url": "https://www.ensembl.org/id/ENSGALG00010019209" } ] } } ], "crossref": [ { "id": "A0A8V0ZGE0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGE0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR019410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGE0", "url": "https://www.orthodb.org/?gene=A0A8V0ZGE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14614:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14614:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876725", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876725", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZGE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWSVGVGNQRISHRMAWVERDHSAHPVPTPCYVQGRQPAAQAAQSHIQPGLECLQGWGIHSLLGQPVQCVTTLWGKNFLLISNLNLPCLSVKPFPLVLSLSTLTNSRSPSCLYAPFKYWKATMRSPRSLLFSKLNKPSSLNLSSQKRCSSPHRTARVGRDLKDHEAPTPRHRQGHQPPHVIPAQAAQGPIQPGLEHLQGWTGHPQPLWAAVPAPHHSQTAELPLTSIPNLPFLPSRTALPPPRRGSAAAMGRRGRAGSVRAAMAGFVRELERRAGPALRLEQRAGGVGCVVWDAALVLAKFLETGAWPLSRRAVLELGAGTGAVGIMAATLGADVTLTDLQELQELLAVNIENNRHLVTGSVRAEVLKWGEDVSEFRPPPDYILMADCIYYEESLEPLLKTLRELTGPDTCVLCCYEQRTVGRNPEIERRYLELLQVDFELERVPLDQHDEEYRSEDIHILTIHRKRTNSPP", "length": 473, "header": "tr|A0A8V0ZGE0-1|A0A8V0ZGE0_CHICK Isoform 1 of Valosin containing protein lysine methyltransferase OS=Gallus gallus OX=9031 GN=VCPKMT PE=4 SV=1 CANONICAL=A0A8V0ZGE0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE0/entry#A0A8V0ZGE0-1", "sequence": { "sequence": "MAWSVGVGNQRISHRMAWVERDHSAHPVPTPCYVQGRQPAAQAAQSHIQPGLECLQGWGIHSLLGQPVQCVTTLWGKNFLLISNLNLPCLSVKPFPLVLSLSTLTNSRSPSCLYAPFKYWKATMRSPRSLLFSKLNKPSSLNLSSQKRCSSPHRTARVGRDLKDHEAPTPRHRQGHQPPHVIPAQAAQGPIQPGLEHLQGWTGHPQPLWAAVPAPHHSQTAELPLTSIPNLPFLPSRTALPPPRRGSAAAMGRRGRAGSVRAAMAGFVRELERRAGPALRLEQRAGGVGCVVWDAALVLAKFLETGAWPLSRRAVLELGAGTGAVGIMAATLGADVTLTDLQELQELLAVNIENNRHLVTGSVRAEVLKWGEDVSEFRPPPDYILMADCIYYEESLEPLLKTLRELTGPDTCVLCCYEQRTVGRNPEIERRYLELLQVDFELERVPLDQHDEEYRSEDIHILTIHRKRTNSPP", "length": 473, "header": "tr|A0A8V0ZGE0-1|A0A8V0ZGE0_CHICK Isoform 1 of Valosin containing protein lysine methyltransferase OS=Gallus gallus OX=9031 GN=VCPKMT PE=4 SV=1 CANONICAL=A0A8V0ZGE0-1" }, "locus": { "chromosome": "5", "start_pos": 57480158, "end_pos": 57476432, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046423.1", "url": "https://www.ensembl.org/id/ENSGALT00010046423.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027637.1", "url": "https://www.ensembl.org/id/ENSGALP00010027637.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 30, "start_aa": "Thr", "end_pos": 30, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr30", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8876725", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876725", "resource": "Reactome", "description": "Protein methylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-lysine N-methyltransferase activity", "id": "GO:0016279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016279", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGE0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 30 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGF7-1", "uniprot_ac": "A0A8V0ZGF7", "uniprot_id": "A0A8V0ZGF7_CHICK", "mass": { "chemical_mass": 38194.0, "monoisotopic_mass": 38194.0 }, "refseq": { "ac": "XP_025007774", "name": "calcium homeostasis modulator protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007774" }, "gene_names": [ { "name": "CALHM3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF7" } ] }, { "name": "CALHM3", "type": "synonym", "evidence": [ { "id": "XP_025007774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007774" } ] } ], "protein_names": [ { "name": "Calcium homeostasis modulator 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF7/entry#names_and_taxonomy" } ] }, { "name": "calcium homeostasis modulator protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025007774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007774" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025007774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007774" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CALHM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF7", "locus": { "chromosome": "6", "start_pos": 24437249, "end_pos": 24440215, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021132", "url": "https://www.ensembl.org/id/ENSGALG00010021132" } ] } } ], "crossref": [ { "id": "A0A8V0ZGF7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "428978", "url": "https://www.ncbi.nlm.nih.gov/gene/428978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428978", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCWSQAL", "url": "https://omabrowser.org/oma/group/RCWSQAL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGF7", "url": "https://www.orthodb.org/?gene=A0A8V0ZGF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025007774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007774", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRFRMIFQYFQSNSESVMNGICGLLALASVKIYTCLDFSCPCLPHYNMAYGLGIMFVPPIALFLCGLILNRQSLVMLEEWRRPQGHRRKDLAVIRYMCCSIMQRAMVAPAVWIVVTLLDGKCLICAFSGSVDPKKFVGFANATLAQAQEMLSRVPCKEDELMRNSTSRRAVSRYLRCWSQALGWSILLILIIAVFLARWLAPCFNQAALLQTRHWSNYIDIEQKIFEETCCEHSRLFAHQCILHFFESMRKEIRQHSFDLPREKEGEEDLLQGITDRDQVNKLLKMWYYEKPPLDVSQVTHRHPLGQERSPPPCAGSCGARSKFTQHTHM", "length": 331, "header": "tr|A0A8V0ZGF7-1|A0A8V0ZGF7_CHICK Isoform 1 of Calcium homeostasis modulator 3 OS=Gallus gallus OX=9031 GN=CALHM3 PE=3 SV=1 CANONICAL=A0A8V0ZGF7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF7/entry#A0A8V0ZGF7-1", "sequence": { "sequence": "MDRFRMIFQYFQSNSESVMNGICGLLALASVKIYTCLDFSCPCLPHYNMAYGLGIMFVPPIALFLCGLILNRQSLVMLEEWRRPQGHRRKDLAVIRYMCCSIMQRAMVAPAVWIVVTLLDGKCLICAFSGSVDPKKFVGFANATLAQAQEMLSRVPCKEDELMRNSTSRRAVSRYLRCWSQALGWSILLILIIAVFLARWLAPCFNQAALLQTRHWSNYIDIEQKIFEETCCEHSRLFAHQCILHFFESMRKEIRQHSFDLPREKEGEEDLLQGITDRDQVNKLLKMWYYEKPPLDVSQVTHRHPLGQERSPPPCAGSCGARSKFTQHTHM", "length": 331, "header": "tr|A0A8V0ZGF7-1|A0A8V0ZGF7_CHICK Isoform 1 of Calcium homeostasis modulator 3 OS=Gallus gallus OX=9031 GN=CALHM3 PE=3 SV=1 CANONICAL=A0A8V0ZGF7-1" }, "locus": { "chromosome": "6", "start_pos": 24440022, "end_pos": 24437825, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051172.1", "url": "https://www.ensembl.org/id/ENSGALT00010051172.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030363.1", "url": "https://www.ensembl.org/id/ENSGALP00010030363.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428978", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BAL1-1", "protein_name": "Calcium homeostasis modulator 3", "gene_name": "CALHM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDKFRMLFQHFQSSSESVMNGICLLLAAVTVKLYSSFDFNCPCLARYNALYGLGLLLTPPLALFLCGLLANRQSVVMVEEWRRPTGHRRKDPGIIRYMCSSVLQRALAAPLVWILLALLDGKCFVCAFSSSVDPEKFLDFANMTPSQVQLFLAKVPCKEDELVRNSPARKAVSRYLRCLSQAIGWSITLLLIVVAFLARCLRPCFDQTVFLQRRYWSNYVDLEQKLFDETCCEHARDFAHRCVLHFFASMQSEMRARGLRRDSASQDPEPLEMPEPPEGLDGGSRKAHLRAVSSREQVNHLLSTWYSRKPPLDLLASPGLWGGGLSHRTPTVAPGTRLSQHTDV", "length": 344 }, "evidence": [ { "id": "A0A8V0ZGF7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGF7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A158-1", "protein_name": "Calcium homeostasis modulator 3", "gene_name": "Calhm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRFRMLFQNFQSSSESVTNGICLLLAAVTVKMYSSLDFNCPCLEHYNALYGLGLLLTPPLALFLCGLLVNRQSVLMVEEWRRPAGHRRKDLGIIRYMCSSVLQRALAAPLVWILLALLDGKCLVCAFSNSVDPEKFLDFANMTPSQVQLFLAKVPCKEDELVKTSPARKAVSRYLRCLSQAIGWSITLLVIVVAFLARCLRPCFNQTVFLQRRYWSNYMDLEQKLFDETCCEHARDFAHRCVLHFFASMQSELRALGLHRDPAGEILESQEPPEPPEEPGSESGKAHLRAISSREQVNHLLSTWYSSKPPLDLAASPRLWEPGLNHRAPIAAPGTKLGHQLDV", "length": 344 }, "evidence": [ { "id": "A0A8V0ZGF7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGF7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BG42-1", "protein_name": "Calcium homeostasis modulator 3", "gene_name": "CALHM3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDKFRTLFLHFQSSSESVMNGVCLLLAMVTVKLYSSFDFNCPCLARYNALYGLGLLFTPPIALFLCGLLANRQSVVMVEEWRRPAGHRRKDPGIVRYMCSSVLQRALAAPVIWILLALLDGKCFVCAFSSSVDPEKFLDFTNMTPSQVQLFLAKVPCKEDELVRNSPARKAVSRYLRCLSQAIGWSLTLLLILLAFLARCLRPCFDQTVFLQRRYWSNYVDLEQKLFDETCCEHARDFAHRCVLHFFASMQSEMQARGLRRDSAGRGPEAPERPEPPDGLDGGSGKAHLRAVSSQEQVDRLLSAWYSSKPPLDLTASSGLWGCGLTHRAPTVVPGTRESPHTDV", "length": 344 }, "evidence": [ { "id": "A0A8V0ZGF7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGF7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7FFW5-1", "protein_name": "Calcium homeostasis modulator protein 3", "gene_name": "calhm3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDRLKLVLQYFQSNSESISNGICIILSLISVKLYTSFDFNCPCLPQYNKMYAMGVMFVPPIILLLLGVLVNRHTGVLMEEWVRPLGKRAKNPAVVKFLLSSMMQRALLAPMVWILMTLLDGKCFICAFSMNVDPKYFTGIPNSTGLELVKIMAKVPCKEDVIFRNSSFRKAVSRYVRCYSQAIGWSILLFLIFLGAVARVIKPCFNHATFLQTRYWSNYLDMEQKLFDETCVLHARDFARKSVLQFFENMRENVTVRMPLSSAPRYSTVQNEFGEEEEERLHGITRQDQVDHLLQTWYECKPELDVTKMAYKPKACITWEDHSGRPLFSDV", "length": 331 }, "evidence": [ { "id": "A0A8V0ZGF7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGF7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "J3QMI4-1", "protein_name": "Calcium homeostasis modulator protein 3", "gene_name": "Calhm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRFRMLFQHLQSSSESVMNGICLLLAAVTVKIYSSLDFNCPCLERYNALYGLGLLLTPPLALFLCGLLVNRQSVLMVEEWRRPAGHRRKDLGIIRYMCSSVLQRALAAPLVWILLALLDGKCFVCAFSNSVDPEKFLDFANMTPRQVQLFLAKVPCKEDELVKNSPARKAVSRYLRCLSQAIGWSITLLVIVVAFLARCLRPCFDQTVFLQRRYWSNYMDLEQKLFDETCCEHARDFAHRCVLHFFANMQSELRALGLRRDPAGGIPESQESSEPPELREDRDSGNGKAHLRAISSREQVDQLLSTWYSSKPPLDLAASPRRWGPGLNHRAPIAAPGTKLCHQLNV", "length": 347 }, "evidence": [ { "id": "A0A8V0ZGF7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGF7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86XJ0-1", "protein_name": "Calcium homeostasis modulator protein 3", "gene_name": "CALHM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDKFRMLFQHFQSSSESVMNGICLLLAAVTVKLYSSFDFNCPCLVHYNALYGLGLLLTPPLALFLCGLLANRQSVVMVEEWRRPAGHRRKDPGIIRYMCSSVLQRALAAPLVWILLALLDGKCFVCAFSSSVDPEKFLDFANMTPSQVQLFLAKVPCKEDELVRDSPARKAVSRYLRCLSQAIGWSVTLLLIIAAFLARCLRPCFDQTVFLQRRYWSNYVDLEQKLFDETCCEHARDFAHRCVLHFFASMRSELQARGLRRGNAGRRLELPAVPEPPEGLDSGSGKAHLRAISSREQVDRLLSTWYSSKPPLDLAASPGLCGGGLSHRAPTLALGTRLSQHTDV", "length": 344 }, "evidence": [ { "id": "A0A8V0ZGF7", "url": "https://omabrowser.org/oma/group/A0A8V0ZGF7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF7" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { 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] } } ], "crossref": [ { "id": "A0A8V0ZGG8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13359", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13359", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGG8", "url": "https://www.orthodb.org/?gene=A0A8V0ZGG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26964", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26964", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZGG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGG8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPPKDVVKIAIQMVGAIPQLIELQQSKPLAAVLKDVCDAWSLPNAERYALQYADGRQTYITESNRGEIKNGSILRLTTSPDQEAERLYSGIQSNNVDVKTDSLKKLASLSQDVTFAQEFINRNGLKQIFYIVEEGNDTGEILAHTLKAFMELMEHDFVSWETLSAAFIKKIVSYVNMNAMDASVQQLSMSILENMVPSSRVLFELVKREVTVDRLLTHLQVTNAQLQLKAMALLIALLLAATDAERRDMMEYLREKNIRQFIHKNIIHSSEPLGDEMAHYLYVLQSVSLNLHERRMRTSVDPYSQTTMRRAQQCPSPLLSLQEQRELLQSLRQAAFESESDAPAGTFSTERRRSLCAKEFRKLGFMNNSNPAEDLRRAPPGLLALDNMVYFSRHTPSAYSRFVLENSSREDKHECPFARSSIQLTLILCEILHVGEPCSETAQAFYPMFFGQDHFFEELFCICIQLVNKTWKEMRATQEDFDKVLQVVREQITRTLSLKPTSLELFKTRVNALNYSEILKLRQTERLHQEETLAVPVLELRERLKPELLELIRQQRLLRLCEGTLFRKISSRRRQDKLWYCRLSPNHKVLHYGDVEEGVQSPPIESLPEKIPVADMKALLVGKECPHTKEKSSGKQNKDVLELAFSIVYDVEEYCLNFVAPTRYEFCLWTDGLNVLLGKEMTSERTQTDLDVLLSMELKLRLLDLENISIPDNPPPVPKPPSNLNFCYDFSYAEQ", "length": 736, "header": "tr|A0A8V0ZGG8-1|A0A8V0ZGG8_CHICK Isoform 1 of Engulfment and cell motility 3 OS=Gallus gallus OX=9031 GN=ELMO3 PE=1 SV=1 CANONICAL=A0A8V0ZGG8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGG8/entry#A0A8V0ZGG8-1", "sequence": { "sequence": "MPPPKDVVKIAIQMVGAIPQLIELQQSKPLAAVLKDVCDAWSLPNAERYALQYADGRQTYITESNRGEIKNGSILRLTTSPDQEAERLYSGIQSNNVDVKTDSLKKLASLSQDVTFAQEFINRNGLKQIFYIVEEGNDTGEILAHTLKAFMELMEHDFVSWETLSAAFIKKIVSYVNMNAMDASVQQLSMSILENMVPSSRVLFELVKREVTVDRLLTHLQVTNAQLQLKAMALLIALLLAATDAERRDMMEYLREKNIRQFIHKNIIHSSEPLGDEMAHYLYVLQSVSLNLHERRMRTSVDPYSQTTMRRAQQCPSPLLSLQEQRELLQSLRQAAFESESDAPAGTFSTERRRSLCAKEFRKLGFMNNSNPAEDLRRAPPGLLALDNMVYFSRHTPSAYSRFVLENSSREDKHECPFARSSIQLTLILCEILHVGEPCSETAQAFYPMFFGQDHFFEELFCICIQLVNKTWKEMRATQEDFDKVLQVVREQITRTLSLKPTSLELFKTRVNALNYSEILKLRQTERLHQEETLAVPVLELRERLKPELLELIRQQRLLRLCEGTLFRKISSRRRQDKLWYCRLSPNHKVLHYGDVEEGVQSPPIESLPEKIPVADMKALLVGKECPHTKEKSSGKQNKDVLELAFSIVYDVEEYCLNFVAPTRYEFCLWTDGLNVLLGKEMTSERTQTDLDVLLSMELKLRLLDLENISIPDNPPPVPKPPSNLNFCYDFSYAEQ", "length": 736, "header": "tr|A0A8V0ZGG8-1|A0A8V0ZGG8_CHICK Isoform 1 of Engulfment and cell motility 3 OS=Gallus gallus OX=9031 GN=ELMO3 PE=1 SV=1 CANONICAL=A0A8V0ZGG8-1" }, "locus": { "chromosome": "11", "start_pos": 1035247, "end_pos": 1027963, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053834.1", "url": "https://www.ensembl.org/id/ENSGALT00010053834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032407.1", "url": "https://www.ensembl.org/id/ENSGALP00010032407.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGG8" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGG8" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGG8" } ], "pmid": "" }, { "name": "cell motility", "id": "GO:0048870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048870", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGG8" } ], "pmid": "" }, { "name": "regulation of vasculogenesis", "id": "GO:2001212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGG8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGG8" }, { "id": "PS51335", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51335" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELMO", "eco_id": "ECO_0000259", "start_pos": 324, "end_pos": 497, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 708, "end_pos": 710 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGM3-1", "uniprot_ac": "A0A8V0ZGM3", "uniprot_id": "A0A8V0ZGM3_CHICK", "mass": { "chemical_mass": 27312.0, "monoisotopic_mass": 27312.0 }, "refseq": { "ac": "XP_015152670", "name": "transmembrane protein 51", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152670" }, "gene_names": [ { "name": "TMEM51", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM3" } ] }, { "name": "TMEM51", "type": "synonym", "evidence": [ { "id": "XP_015152670", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152670" } ] } ], "protein_names": [ { "name": "Transmembrane protein 51", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM3/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 51", "type": "synonym", "evidence": [ { "id": "XP_015152670", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152670" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015152670.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152670", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152670" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM3", "locus": { "chromosome": "21", "start_pos": 4946467, "end_pos": 4953890, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020971", "url": "https://www.ensembl.org/id/ENSGALG00010020971" } ] } } ], "crossref": [ { "id": "A0A8V0ZGM3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "771913", "url": "https://www.ncbi.nlm.nih.gov/gene/771913", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029265", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029265", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771913", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771913", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVMSTNY", "url": "https://omabrowser.org/oma/group/EVMSTNY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGH0", "url": "https://www.orthodb.org/?gene=A0A8V0ZGH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGM3", "url": "https://www.orthodb.org/?gene=A0A8V0ZGM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16015:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16015:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15345", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15345", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015152670", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152670", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPSRTNGSHYALTAIGLGMLILGVILAVWNLVPGFGHPDKLNAGNSSKPDRGGGGIFKSKTFSVAYVLVGAGLLLLLLSLCLNVRDKKRQSEDIPRVVQHQASVEPSQQEEDSQEEDEDVSSRYYVPSYEEVMNAGYSEPRDPERNRRISVSLPSYESLTGLEEGTQPSGAANAEPSTERPPGRNNSRLSKRLKPLKVRRIKSEKLHLKDIRLNLGDGSSTGPITIEPLTPPPKYEDIQEKAPGSQQLT", "length": 250, "header": "tr|A0A8V0ZGM3-1|A0A8V0ZGM3_CHICK Isoform 1 of Transmembrane protein 51 OS=Gallus gallus OX=9031 GN=TMEM51 PE=4 SV=1 CANONICAL=A0A8V0ZGM3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM3/entry#A0A8V0ZGH0-1", "sequence": { "sequence": "MVATRGHQGCSEVANAQWPHLAPTGRTTSKPDRGGGGIFKSKTFSVAYVLVGAGLLLLLLSLCLNVRDKKRQSEDIPRVVQHQASVEPSQQEEDSQEEDEDVSSRYYVPSYEEVMNAGYSEPRDPERNRRISVSLPSYESLTGLEEGTQPSGAANAEPSTERPPGRNNSRLSKRLKPLKVRRIKSEKLHLKDIRLNLGDGSSTGPITIEPLTPPPKYEDIQEKAPGSQQLT", "length": 231, "header": "tr|A0A8V0ZGH0-1|A0A8V0ZGM3_CHICK Computationally mapped isoform of Transmembrane protein 51 OS=Gallus gallus OX=9031 GN=TMEM51 PE=4 SV=1 CANONICAL=A0A8V0ZGM3-1" }, "locus": { "chromosome": "21", "start_pos": 4948883, "end_pos": 4947262, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050684.1", "url": "https://www.ensembl.org/id/ENSGALT00010050684.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029928.1", "url": "https://www.ensembl.org/id/ENSGALP00010029928.1" } ] } }, { "isoform_ac": "A0A8V0ZGM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM3/entry#A0A8V0ZGM3-1", "sequence": { "sequence": "MAPSRTNGSHYALTAIGLGMLILGVILAVWNLVPGFGHPDKLNAGNSSKPDRGGGGIFKSKTFSVAYVLVGAGLLLLLLSLCLNVRDKKRQSEDIPRVVQHQASVEPSQQEEDSQEEDEDVSSRYYVPSYEEVMNAGYSEPRDPERNRRISVSLPSYESLTGLEEGTQPSGAANAEPSTERPPGRNNSRLSKRLKPLKVRRIKSEKLHLKDIRLNLGDGSSTGPITIEPLTPPPKYEDIQEKAPGSQQLT", "length": 250, "header": "tr|A0A8V0ZGM3-1|A0A8V0ZGM3_CHICK Isoform 1 of Transmembrane protein 51 OS=Gallus gallus OX=9031 GN=TMEM51 PE=4 SV=1 CANONICAL=A0A8V0ZGM3-1" }, "locus": { "chromosome": "21", "start_pos": 4948833, "end_pos": 4947262, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050682.1", "url": "https://www.ensembl.org/id/ENSGALT00010050682.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029927.1", "url": "https://www.ensembl.org/id/ENSGALP00010029927.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771913", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771913", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AE69-1", "protein_name": "Transmembrane protein 51", "gene_name": "Tmem51", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMAQSKANGSHYALTAIGLGMLVLGVIMAMWNLVPGFSPADKPTAQGNKTEGGGGILKSKTFSVAYVLVGAGVMLLLLSICLSIRDKRKLRQSEELARIQQQAGAVPPSQEEDSQEEEEEASSRYYVPSYEEVMNTGYPESRDQEQNPRLSISLPSYESLTGLDEATPTSTRAETETSPGHAPDRQNSKLAKRLKPLKVRRIKSEKLHLKDFRITLPDKNVPPPSIEPLTPPPQYDEVQAKAPEARPPD", "length": 249 }, "evidence": [ { "id": "A0A8V0ZGM3", "url": "https://omabrowser.org/oma/group/A0A8V0ZGM3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3L6M7-1", "protein_name": "Transmembrane protein 51", "gene_name": "TMEM51", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQSKANGSHYALTAIGLGMLVLGVIMAMWNLVPGFSASEKPTAQGNNKTEIGSSILKSKTFSVAYVLVGAGVMLLLLSICLSIRDKRKQRQGEELAHIQQPGVEPHAQEEDSQEEEEEASSRYYVPSYEEVMNTNYSEAREPDQNPRMSISLPSYESLTGLDETTPTTTRADIETSPGNPPDRQNSKLAKRLKPLKVRRIKSEKLHLKDFRINLPDKNVPPPSIEPLTPPPQYEEVQEKAPDARPPD", "length": 248 }, "evidence": [ { "id": "A0A8V0ZGM3", "url": "https://omabrowser.org/oma/group/A0A8V0ZGM3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q99LG1-1", "protein_name": "Transmembrane protein 51", "gene_name": "Tmem51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMAQSKANGSHYALTAIGLGMLVLGVIMAMWNLVPGFSPADKPTSQGNKTEGGGGILKSKTFSVAYVLVGAGMMLLLLAICLSIRDKRRMRQSEELARIQQQAGTVPHSQEEDSQEEEEDVSSRYYVPSYEEVMNTGYPETRGQEQNPRLSISLPSYESLTGLDEATPTSTRAETETSPGHAPDRQNSKLAKRLKPLKVRRIKSEKLHLKDFRITLPDKNVPPPSIEPLTPPPLYDEVQAKAPDARPPD", "length": 249 }, "evidence": [ { "id": "A0A8V0ZGM3", "url": "https://omabrowser.org/oma/group/A0A8V0ZGM3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NW97-1", "protein_name": "Transmembrane protein 51", "gene_name": "TMEM51", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMAQSKANGSHYALTAIGLGMLVLGVIMAMWNLVPGFSAAEKPTAQGSNKTEVGGGILKSKTFSVAYVLVGAGVMLLLLSICLSIRDKRKQRQGEDLAHVQHPTGAGPHAQEEDSQEEEEEDEEAASRYYVPSYEEVMNTNYSEARGEEQNPRLSISLPSYESLTGLDETTPTSTRADVEASPGNPPDRQNSKLAKRLKPLKVRRIKSEKLHLKDFRINLPDKNVPPPSIEPLTPPPQYDEVQEKAPDTRPPD", "length": 253 }, "evidence": [ { "id": "A0A8V0ZGM3", "url": "https://omabrowser.org/oma/group/A0A8V0ZGM3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 46, "end_pos": 48 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGI1-1", "uniprot_ac": "A0A8V0ZGI1", "uniprot_id": "A0A8V0ZGI1_CHICK", "mass": { "chemical_mass": 25781.0, "monoisotopic_mass": 25781.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "PDZ domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI1", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZGI1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGI1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48484", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48484", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48484:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48484:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRNSLLQESGLSASLLIFSDREAEKVIEGIMPHKWENDRKKGSTTSSLKMDRKSNAGNRKSRKFRSISRSLILCNARNSDDGSSPDEKCPDPFEISTNWSQEEFDCCPRAQLPSTSETEDSSPDPPCVITSTAQSKAAANENCNNMRKKLLIKDNCICRLCATRGNSSSGIKLSRSPNCASLWKGISGCQVPAGGTTNRDGCLSPRNELLTLNGQSLKDLSSKEAESLIQSTTQL", "length": 236, "header": "tr|A0A8V0ZGI1-1|A0A8V0ZGI1_CHICK Isoform 1 of PDZ domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZGI1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI1/entry#A0A8V0ZGI1-1", "sequence": { "sequence": "MKRNSLLQESGLSASLLIFSDREAEKVIEGIMPHKWENDRKKGSTTSSLKMDRKSNAGNRKSRKFRSISRSLILCNARNSDDGSSPDEKCPDPFEISTNWSQEEFDCCPRAQLPSTSETEDSSPDPPCVITSTAQSKAAANENCNNMRKKLLIKDNCICRLCATRGNSSSGIKLSRSPNCASLWKGISGCQVPAGGTTNRDGCLSPRNELLTLNGQSLKDLSSKEAESLIQSTTQL", "length": 236, "header": "tr|A0A8V0ZGI1-1|A0A8V0ZGI1_CHICK Isoform 1 of PDZ domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZGI1-1" }, "locus": { "chromosome": "10", "start_pos": 12151372, "end_pos": 12137802, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050622.1", "url": "https://www.ensembl.org/id/ENSGALT00010050622.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029886.1", "url": "https://www.ensembl.org/id/ENSGALP00010029886.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "induction of positive chemotaxis", "id": "GO:0050930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI1" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 171, "end_pos": 236, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGI5-1", "uniprot_ac": "A0A8V0ZGI5", "uniprot_id": "A0A8V0ZGI5_CHICK", "mass": { "chemical_mass": 29613.0, "monoisotopic_mass": 29613.0 }, "refseq": { "ac": "NP_001264486", "name": "TLC domain-containing protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264486" }, "gene_names": [ { "name": "TLCD4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5" } ] }, { "name": "TLCD4", "type": "synonym", "evidence": [ { "id": "NP_001264486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264486" } ] }, { "name": "TMEM56", "type": "synonym", "evidence": [ { "id": "NP_001264486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264486" } ] } ], "protein_names": [ { "name": "TLC domain containing 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5/entry#names_and_taxonomy" } ] }, { "name": "TLC domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "NP_001264486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264486" } ] }, { "name": "transmembrane protein 56", "type": "synonym", "evidence": [ { "id": "NP_001264486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264486" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.231919.1, BX934812.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03376186 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On Sep 23, 2021 this sequence version replaced NP_001264486.1. Sequence Note: This RefSeq record was created from genomic sequence and transcript data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001264486", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264486" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TLCD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5", "locus": { "chromosome": "8", "start_pos": 13076116, "end_pos": 13116776, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020982", "url": "https://www.ensembl.org/id/ENSGALG00010020982" } ] } } ], "crossref": [ { "id": "A0A8V0ZGI5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "424483", "url": "https://www.ncbi.nlm.nih.gov/gene/424483", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424483", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424483", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPVYYSH", "url": "https://omabrowser.org/oma/group/MPVYYSH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGI5", "url": "https://www.orthodb.org/?gene=A0A8V0ZGI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGN7", "url": "https://www.orthodb.org/?gene=A0A8V0ZGN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13439", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13439", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13439:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13439:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264486", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264486", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASFSNLTIGIALASFTIFQLLFHVLSSWVSTRITPGFSNLSQKRKIEWNSRTVSTFHALVVGGFCLYILLYDEAVNADHLWGDPSIVKLNIAITTGYLISDLLLIICYWKAIGDKFFVVHHLAALYAYYFVLSKGLLAYFGNFRLLAEFSTPFVNQRWFFEVLGYPKSSKANMINGVLMTVVFFVVRIAVMPMYYSRVFSSFGTEGFQRLGFAAQSAWIISSVVLDVMNLMWMAKITKGCYKVICLVGREEAKTHKNGKSD", "length": 262, "header": "tr|A0A8V0ZGI5-1|A0A8V0ZGI5_CHICK Isoform 1 of TLC domain containing 4 OS=Gallus gallus OX=9031 GN=TLCD4 PE=4 SV=1 CANONICAL=A0A8V0ZGI5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5/entry#A0A8V0ZGI5-1", "sequence": { "sequence": "MASFSNLTIGIALASFTIFQLLFHVLSSWVSTRITPGFSNLSQKRKIEWNSRTVSTFHALVVGGFCLYILLYDEAVNADHLWGDPSIVKLNIAITTGYLISDLLLIICYWKAIGDKFFVVHHLAALYAYYFVLSKGLLAYFGNFRLLAEFSTPFVNQRWFFEVLGYPKSSKANMINGVLMTVVFFVVRIAVMPMYYSRVFSSFGTEGFQRLGFAAQSAWIISSVVLDVMNLMWMAKITKGCYKVICLVGREEAKTHKNGKSD", "length": 262, "header": "tr|A0A8V0ZGI5-1|A0A8V0ZGI5_CHICK Isoform 1 of TLC domain containing 4 OS=Gallus gallus OX=9031 GN=TLCD4 PE=4 SV=1 CANONICAL=A0A8V0ZGI5-1" }, "locus": { "chromosome": "8", "start_pos": 13096669, "end_pos": 13080204, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050714.1", "url": "https://www.ensembl.org/id/ENSGALT00010050714.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029945.1", "url": "https://www.ensembl.org/id/ENSGALP00010029945.1" } ] } }, { "isoform_ac": "A0A8V0ZGN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5/entry#A0A8V0ZGN7-1", "sequence": { "sequence": "SQSFSSVLLLLPCQKVLLYDCLSHLSLLSTFHALVVGGFCLYILLYDEAVNADHLWGDPSIVKLNIAITTGYLISDLLLIICYWKAIGDKFFVVHHLAALYAYYFVLSKGLLAYFGNFRLLAEFSTPFVNQRWFFEVLGYPKSSKANMINGVLMTVVFFVVRIAVMPMYYSRVFSSFGTEGFQRLGFAAQSAWIISSVVLDVMNLMWMAKITKGCYKVICLVGREEAKTHKNGKSD", "length": 236, "header": "tr|A0A8V0ZGN7-1|A0A8V0ZGN7_CHICK Computationally mapped isoform of TLC domain containing 4 OS=Gallus gallus OX=9031 GN=TLCD4 PE=4 SV=1 CANONICAL=A0A8V0ZGI5-1" }, "locus": { "chromosome": "8", "start_pos": 13092679, "end_pos": 13080204, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050713.1", "url": "https://www.ensembl.org/id/ENSGALT00010050713.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029944.1", "url": "https://www.ensembl.org/id/ENSGALP00010029944.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424483", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424483", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AN10-1", "protein_name": "TLC domain containing 4", "gene_name": "TLCD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDTSSTLVISIVIIGFFTFQLLFHFVSSWFSAKVSPGFNNLNFKKKIEWNSRVVSTCHSLVVGVVGLYIFWFDEATIADPLWGDPSFVKVNIAVSSSYLISDLFILILYWKVIGDKYYIIHHCTALYAYYFILSEGVLAYIGNFRLLAELSTPFVNQRWFFEALSYPRVSKAYVINGVLMTAVFFVMRIASIPPLYAYIYSVLGTEAYRRLGALIQCSWISSCVVLDVMNVMWMVKISKGCIKVISLFRQEKARRSLQNGKLD", "length": 263 }, "evidence": [ { "id": "A0A8V0ZGI5", "url": "https://omabrowser.org/oma/group/A0A8V0ZGI5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M2B9S8-1", "protein_name": "TLC domain-containing protein 4 isoform X1", "gene_name": "tlcd4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEGMSVKHLLYFSPGAWGRVAMDPFSQLILLISVVSFFFFQWLFHSVSPWASSRISPGFLKLTHKQKIEWNSRTVSTLHALLVGLFCLYILFFDEAVNQDPVWGDPTLVKINVSITTGYLISDLLLIFYYWRAIGDKFFVIHHLAALYAYYYVLGQGMLPYFANFRLLAEFSTPCVNQRWFFEVLGYPKSSRPNMANGVLMAAVFFLVRIAVMPVYYSRMCSVYGTEAFYRVSFGGRSAWIFSSICLDIMNVMWMHKIFRGCYKVLQSSRKSKAESQENGKTD", "length": 284 }, "evidence": [ { "id": "A0A8V0ZGI5", "url": "https://omabrowser.org/oma/group/A0A8V0ZGI5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A9J7J9G9-1", "protein_name": "TLC domain-containing protein 4", "gene_name": "LOC100772772", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEANTKLVIGIVCSSFVIFQILFHFVSYWFSAKVSPGYNSLSIEKKIEWNSRVVSTCHSLLVGTYGLYLFLFDEPTIADPLWGDPACVKLNIATASGYLVSDLLIILLNWKVIGDKFFVIHHCAALTAYFLMLRDGVLAYIANFRLLAELSSPFVNQRWFFETLKYPKFSKANVINGILMTVVFFVVRIIAIPPLYFFIYSVYGTEAFIRLGFTIQFTWITTCLILDVMNVMWMIKITKGCIKVISLIRQEKAKNSLQNGKLD", "length": 263 }, "evidence": [ { "id": "A0A8V0ZGI5", "url": "https://omabrowser.org/oma/group/A0A8V0ZGI5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4AAE5-1", "protein_name": "TLC domain containing 4", "gene_name": "Tlcd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEANTNVVIGTVCCSFVTFQLLFHFISCWFSARVSLGYNSLSTEKKIEWNSRVVSTCHSMLVGIFGLYLFFFDEATIADPLWGDPSLVKINISTASGYLISDLLIILFNWKVIGDKFFIIHHCAGLIAYYFVLKIGVLAYIANFRLLAELSSPFVNQRWFFEVLKYPKFSKVNVINGILMTVVFFIVRIIAIPPMYFYVYSVYGTEPYIRLGSVVHFVWISSCIVLDVMNIMWMIKITKGCMKVISLIRQEKAKDSLQNGKLD", "length": 263 }, "evidence": [ { "id": "A0A8V0ZGI5", "url": "https://omabrowser.org/oma/group/A0A8V0ZGI5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B7S9-1", "protein_name": "TLC domain containing 4", "gene_name": "TLCD4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDTNTILLISTCFASFFTFQIIFHVVSYWFSAKISPGFNNLNFKKKIEWNSRVVSTCHSLVVGLVGLYIFLFDEAGIADPLWGDTSLGKVNVAIASGYLVSDLLILIWYWKVIGDKYFVIHHCTALYAYHFVLNDGVLVYVGNFRLLAELSSPFVNQRWFFEALKYPKFSKANVINGILMTVVFFVVRIASIPPYYGYMYSVFGTEAYMRLGFLIQFSWISTCVVLDVMNVMWMIKISKGCIKVISLLRQEKARKSLQNGKLD", "length": 263 }, "evidence": [ { "id": "A0A8V0ZGI5", "url": "https://omabrowser.org/oma/group/A0A8V0ZGI5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47153-1", "protein_name": "Topoisomerase I damage affected protein 4", "gene_name": "TDA4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNANSTTTAIGLTSPFEKLSFFPHSSNLILAHLHEIIFSFVFYQLAFSVVAPFLNKVVFRKHYTTIRDPLLKIDFNVHTVSMIQAVVSNTVLLPTLTTPMHYNVVTYTDSYSSMVSSLSAGYFIWDLTMCVRYFKLYGLEFTGHAIGSVYVMLLSLRPFCQPWIGRFLIYEASTPFVNINWFIMQCNAKSKNSIPLWFNVVNGLLLMTVFFVVRICWGSIASALLFRQMWKVRDELPKFSAVTMMSLNIFMNLLNVLWFKKMIRIAKKLAKPAPTSKLD", "length": 279 }, "evidence": [ { "id": "A0A8V0ZGI5", "url": "https://omabrowser.org/oma/group/A0A8V0ZGI5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8CGF5-1", "protein_name": "TLC domain-containing protein 4", "gene_name": "Tlcd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEASTKAAVGSGAMEASTKAVICTVCSSFVVFQILFHFVSYWFSARVSSGYNSLSIDKKIEWNSRVVSTCHSLLVGIFGLYLFFFDEATITDPLWGDPTYVNINIATASGYLISDLLIILFNWKVIGDKFFIIHHCAGLTAYYFVLTTGALAYIANFRLLAELSSPFVNQRWFFEALKYPKFSKANVINGILMTVVFFIVRIISIPPMYFFLYSVYGTEPYIRFGFVIQSVWIVTCVILDVMNIMWMIKITKGCIKVISLIRQEKAKDSLQNGKLD", "length": 276 }, "evidence": [ { "id": "A0A8V0ZGI5", "url": "https://omabrowser.org/oma/group/A0A8V0ZGI5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96MV1-1", "protein_name": "TLC domain-containing protein 4", "gene_name": "TLCD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEINTKLLISVTCISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKKKIEWNSRVVSTCHSLVVGIFGLYIFLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIIILYWKVIGDKFFIMHHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQRWFFEALKYPKFSKAIVINGILMTVVFFIVRIASMLPHYGFMYSVYGTEPYIRLGVLIQLSWVISCVVLDVMNVMWMIKISKGCIKVISHIRQEKAKNSLQNGKLD", "length": 263 }, "evidence": [ { "id": "A0A8V0ZGI5", "url": "https://omabrowser.org/oma/group/A0A8V0ZGI5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGI5" }, { "id": "PS50922", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50922" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TLC", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 246, "start_aa": "Lys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 35 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 40, "end_pos": 42 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGJ2-1", "uniprot_ac": "A0A8V0ZGJ2", "uniprot_id": "A0A8V0ZGJ2_CHICK", "mass": { "chemical_mass": 140715.0, "monoisotopic_mass": 140715.0 }, "refseq": {}, "gene_names": [ { "name": "FHAD1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ2" } ] } ], "protein_names": [ { "name": "Forkhead associated phosphopeptide binding domain 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FHAD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ2", "locus": { "chromosome": "21", "start_pos": 4928398, "end_pos": 4944811, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020955", "url": "https://www.ensembl.org/id/ENSGALG00010020955" } ] } } ], "crossref": [ { "id": "A0A8V0ZGJ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGJ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZGJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18853", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18853", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18853:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18853:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZGJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAFLRSSEECFQLKQQRTTIGRHEGSDIVLKGTFVNGCQVQNAAVHVGPGDVLRFGARGASFELMVDGVPQKPSYPLAQRCTAWAVQGAAEPQHGAHLPPLQSQHHTSTWVDPTPHPSLRKRPISAWTRSATMTVPMDALNPPPAERPAWTTNSSSSGMGDPFLGIHSTDCSLQEKDEKLLSLEKEIGRLSAFEAESKQKDTVIRDLQGELASMAESMAAVRNDVELTQRLLTFEGEIRAKTEEIKALKEQISNLQKGSSEIFSHSLQERDLEMGNLRRESEKLKRDHALTTGLVTSLQREIAVKEQKIQQLKQEVEKTKKANREKDNQLAAVSAKCSRIKEEMKRELGEREMAAYQKRIGELECELKGLQEEVQKCHIDQKAIQTQLAEKAKVEEELKSTCKRKSLQLQEMGRRERLLKSDVDRVQGQLESFKSQVMRVCSPHAAGESGKALTVQQVVEKVRHIWEENQQSQAQEKCLQEEISSKLSKEKEMTENVEVFKKSLRELQAFLRASFCSSSLKSELSKLEAMLVDPLVLDIHAAVVEITRVVLSWLEEAEQLLASTGLELPTSKKGLTACLKRLLEKYRETERRNEMLQVQLEEVRESRDALLQESLEELKAKHEQDLQIKINQIILEKEEEKAKILESTVLKEKEKHKQCLDEEKKRIQDLESHLRSMAEIIEGKSKEQEAMDLKLQEAVHDLEEATTREMMLRQQVRMQDEQLKILQDESEVLKRKMQEEIAEYKEQIKQHSRTIVALEDRLLEAEQQQKALKEDNVVLEERIKGLQDDACRSTSGASQEAKESHCCGLEELTAMQSILQAKEAAIVGLTKELSETRARMSDMRGELSEKQKAELEQSLHRVKSQERELGVLRGKLSGMSDLVAKKDRELQAAAAELRKVQEDCRALKDASRRMAEELEMLPQAQAIPATPEESSEQELALDLANLGVRCRGLRHEETIQRQKEGLAELRERIKVLEKTQASAVLGRASELLMVQKAALPEKVAQKAGLQVEPAPLPGAEFKCSKCLGQLPDGSSHGAMSVEVLEDSDLSERMYLDLICALGRLMNMKELEGMQPMEHVPQEEREKVGQQRWRDLGLLYERISKLKDRLERKEERLREYETSIEQLRLNQESLQTCQEEMLRLEDEVYREAEEKALLREALERTRAELGQEKRLNRAARQRKSLAENGEKRKEKELPNRARSSKERGGKPGDQQPSLLVKVKSKERVVGELQAMGST", "length": 1238, "header": "tr|A0A8V0ZGJ2-1|A0A8V0ZGJ2_CHICK Isoform 1 of Forkhead associated phosphopeptide binding domain 1 OS=Gallus gallus OX=9031 GN=FHAD1 PE=4 SV=1 CANONICAL=A0A8V0ZGJ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ2/entry#A0A8V0ZGJ2-1", "sequence": { "sequence": "MRAFLRSSEECFQLKQQRTTIGRHEGSDIVLKGTFVNGCQVQNAAVHVGPGDVLRFGARGASFELMVDGVPQKPSYPLAQRCTAWAVQGAAEPQHGAHLPPLQSQHHTSTWVDPTPHPSLRKRPISAWTRSATMTVPMDALNPPPAERPAWTTNSSSSGMGDPFLGIHSTDCSLQEKDEKLLSLEKEIGRLSAFEAESKQKDTVIRDLQGELASMAESMAAVRNDVELTQRLLTFEGEIRAKTEEIKALKEQISNLQKGSSEIFSHSLQERDLEMGNLRRESEKLKRDHALTTGLVTSLQREIAVKEQKIQQLKQEVEKTKKANREKDNQLAAVSAKCSRIKEEMKRELGEREMAAYQKRIGELECELKGLQEEVQKCHIDQKAIQTQLAEKAKVEEELKSTCKRKSLQLQEMGRRERLLKSDVDRVQGQLESFKSQVMRVCSPHAAGESGKALTVQQVVEKVRHIWEENQQSQAQEKCLQEEISSKLSKEKEMTENVEVFKKSLRELQAFLRASFCSSSLKSELSKLEAMLVDPLVLDIHAAVVEITRVVLSWLEEAEQLLASTGLELPTSKKGLTACLKRLLEKYRETERRNEMLQVQLEEVRESRDALLQESLEELKAKHEQDLQIKINQIILEKEEEKAKILESTVLKEKEKHKQCLDEEKKRIQDLESHLRSMAEIIEGKSKEQEAMDLKLQEAVHDLEEATTREMMLRQQVRMQDEQLKILQDESEVLKRKMQEEIAEYKEQIKQHSRTIVALEDRLLEAEQQQKALKEDNVVLEERIKGLQDDACRSTSGASQEAKESHCCGLEELTAMQSILQAKEAAIVGLTKELSETRARMSDMRGELSEKQKAELEQSLHRVKSQERELGVLRGKLSGMSDLVAKKDRELQAAAAELRKVQEDCRALKDASRRMAEELEMLPQAQAIPATPEESSEQELALDLANLGVRCRGLRHEETIQRQKEGLAELRERIKVLEKTQASAVLGRASELLMVQKAALPEKVAQKAGLQVEPAPLPGAEFKCSKCLGQLPDGSSHGAMSVEVLEDSDLSERMYLDLICALGRLMNMKELEGMQPMEHVPQEEREKVGQQRWRDLGLLYERISKLKDRLERKEERLREYETSIEQLRLNQESLQTCQEEMLRLEDEVYREAEEKALLREALERTRAELGQEKRLNRAARQRKSLAENGEKRKEKELPNRARSSKERGGKPGDQQPSLLVKVKSKERVVGELQAMGST", "length": 1238, "header": "tr|A0A8V0ZGJ2-1|A0A8V0ZGJ2_CHICK Isoform 1 of Forkhead associated phosphopeptide binding domain 1 OS=Gallus gallus OX=9031 GN=FHAD1 PE=4 SV=1 CANONICAL=A0A8V0ZGJ2-1" }, "locus": { "chromosome": "21", "start_pos": 4944612, "end_pos": 4928636, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050639.1", "url": "https://www.ensembl.org/id/ENSGALT00010050639.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029896.1", "url": "https://www.ensembl.org/id/ENSGALP00010029896.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 115, "start_aa": "Thr", "end_pos": 115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr115", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ2" }, { "id": "PF28447", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28447" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCDC27/FHAD1 coiled-coil", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 225, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 115 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGJ3-1", "uniprot_ac": "A0A8V0ZGJ3", "uniprot_id": "A0A8V0ZGJ3_CHICK", "mass": { "chemical_mass": 62037.0, "monoisotopic_mass": 62037.0 }, "refseq": {}, "gene_names": [ { "name": "SNTA1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ] } ], "protein_names": [ { "name": "Alpha-1-syntrophin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNTA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3", "locus": { "chromosome": "20", "start_pos": 2621742, "end_pos": 2612504, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022144", "url": "https://www.ensembl.org/id/ENSGALG00010022144" } ] } } ], "crossref": [ { "id": "A0A8V0ZGJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01258", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01258", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06801", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06801", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGJ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZGJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10554", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10554", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10554:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10554:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9913351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGRRGARSGLLELRGPGGQWLRVLLTLSDDTLSVSPADGPGPGEPQPAQLNGGEQSSGVPEALANIRRTVRVVKQDVGGLGISIKGGRENKMPILISKIFKGLAADQTEALYVGDAILSVNGTDLSEATHDEAVQALKKTGKEVVLEVKYMKEISPYFKNSAAGPTVSWDPSPAVPQKHSSPVLPPRESRTVPLRMCYVSRKCLPADPEHRYLEVCSADGRVALFLRAKDEAAAQSWLGAIQSAAGALLPRVKEELRAQLAGAGTVSGRDVKHVGWLTEQLPGAGTRNLLAVLTEKELLLYGSLPQSRDALGKPVHSYPLIATRLVHSGPAKGSALLEAELAFALRAGTRLGVQSHLFSLESPRELALWTRLLVDGTHGAAELAQEVSAACTWKGQECTLSVHIDKGFTISATEPGLSRTVLLQQPFEKLQMSSDDGTKMLYLDFGGPEGEIQLDLHSCPKTIVFIIHSFLSAKMLTGQHSSTRHRDGGLPAPSTAQLQGRMDGSCRSALFAKLFLVAAMGAAVLWDGWALRFTLPTPHRFISWFWREGCRVAAGKHVTNRKILHGNASSCLILVK", "length": 578, "header": "tr|A0A8V0ZGJ3-1|A0A8V0ZGJ3_CHICK Isoform 1 of Alpha-1-syntrophin OS=Gallus gallus OX=9031 GN=SNTA1 PE=1 SV=1 CANONICAL=A0A8V0ZGJ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3/entry#A0A8V0ZGJ3-1", "sequence": { "sequence": "MAAGRRGARSGLLELRGPGGQWLRVLLTLSDDTLSVSPADGPGPGEPQPAQLNGGEQSSGVPEALANIRRTVRVVKQDVGGLGISIKGGRENKMPILISKIFKGLAADQTEALYVGDAILSVNGTDLSEATHDEAVQALKKTGKEVVLEVKYMKEISPYFKNSAAGPTVSWDPSPAVPQKHSSPVLPPRESRTVPLRMCYVSRKCLPADPEHRYLEVCSADGRVALFLRAKDEAAAQSWLGAIQSAAGALLPRVKEELRAQLAGAGTVSGRDVKHVGWLTEQLPGAGTRNLLAVLTEKELLLYGSLPQSRDALGKPVHSYPLIATRLVHSGPAKGSALLEAELAFALRAGTRLGVQSHLFSLESPRELALWTRLLVDGTHGAAELAQEVSAACTWKGQECTLSVHIDKGFTISATEPGLSRTVLLQQPFEKLQMSSDDGTKMLYLDFGGPEGEIQLDLHSCPKTIVFIIHSFLSAKMLTGQHSSTRHRDGGLPAPSTAQLQGRMDGSCRSALFAKLFLVAAMGAAVLWDGWALRFTLPTPHRFISWFWREGCRVAAGKHVTNRKILHGNASSCLILVK", "length": 578, "header": "tr|A0A8V0ZGJ3-1|A0A8V0ZGJ3_CHICK Isoform 1 of Alpha-1-syntrophin OS=Gallus gallus OX=9031 GN=SNTA1 PE=1 SV=1 CANONICAL=A0A8V0ZGJ3-1" }, "locus": { "chromosome": "20", "start_pos": 2621369, "end_pos": 2612703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053866.1", "url": "https://www.ensembl.org/id/ENSGALT00010053866.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032432.1", "url": "https://www.ensembl.org/id/ENSGALP00010032432.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 168, "start_aa": "Thr", "end_pos": 168, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr168", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-9913351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9913351", "resource": "Reactome", "description": "Formation of the dystrophin-glycoprotein complex (DGC)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "dystrophin-associated glycoprotein complex", "id": "GO:0016010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "sodium channel regulator activity", "id": "GO:0017080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "nitric-oxide synthase binding", "id": "GO:0050998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050998", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of ventricular cardiac muscle cell membrane repolarization", "id": "GO:0060307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "regulation of heart rate", "id": "GO:0002027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "ventricular cardiac muscle cell action potential", "id": "GO:0086005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" }, { "name": "regulation of sodium ion transmembrane transport", "id": "GO:1902305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902305", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 154, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZGJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ3" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 248, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 168 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 569, "end_pos": 571 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGJ7-1", "uniprot_ac": "A0A8V0ZGJ7", "uniprot_id": "A0A8V0ZGJ7_CHICK", "mass": { "chemical_mass": 29826.0, "monoisotopic_mass": 29826.0 }, "refseq": {}, "gene_names": [ { "name": "FAM3D", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7" } ] } ], "protein_names": [ { "name": "FAM3 metabolism regulating signaling molecule D", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM3D", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7", "locus": { "chromosome": "12", "start_pos": 12055756, "end_pos": 12060559, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020958", "url": "https://www.ensembl.org/id/ENSGALG00010020958" } ] } } ], "crossref": [ { "id": "A0A8V0ZGJ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007152", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007152", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13940", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13940", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416069", "url": "https://www.ncbi.nlm.nih.gov/gene/416069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039220", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039220", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416069", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416069", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWFIVQT", "url": "https://omabrowser.org/oma/group/TWFIVQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGJ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZGJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C5S9", "url": "https://www.orthodb.org/?gene=E1C5S9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5S9", "url": "https://www.uniprot.org/uniprotkb/E1C5S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C5S9-1", "url": "https://www.uniprot.org/uniprotkb/E1C5S9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRMTGVIRLLVLLATLLGSWFIVQTYFERSGRAISLRSWLGATSEPMSTPPQPRHKCANKRDCPADHFAFRIISGAANVVGPSICFEDRILMSTVKNNIGRGLNIALVNGELGPGGPKALCTANFRTASTTVHVGLGPRGASLETHPDCVGNFQPAGKSGQLLKVGSFDMYSGDVTQLETFLQEIKDGTIMLVATYDDAATKMNNKVRALFSALGSRYANQLGFRDNWVFLGAKGLKGKSPFEEHIKNDQKTNKYEGWPELLEMEGCAPRKQD", "length": 273, "header": "tr|A0A8V0ZGJ7-1|A0A8V0ZGJ7_CHICK Isoform 1 of FAM3 metabolism regulating signaling molecule D OS=Gallus gallus OX=9031 GN=FAM3D PE=1 SV=1 CANONICAL=A0A8V0ZGJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7/entry#A0A8V0ZGJ7-1", "sequence": { "sequence": "MRMTGVIRLLVLLATLLGSWFIVQTYFERSGRAISLRSWLGATSEPMSTPPQPRHKCANKRDCPADHFAFRIISGAANVVGPSICFEDRILMSTVKNNIGRGLNIALVNGELGPGGPKALCTANFRTASTTVHVGLGPRGASLETHPDCVGNFQPAGKSGQLLKVGSFDMYSGDVTQLETFLQEIKDGTIMLVATYDDAATKMNNKVRALFSALGSRYANQLGFRDNWVFLGAKGLKGKSPFEEHIKNDQKTNKYEGWPELLEMEGCAPRKQD", "length": 273, "header": "tr|A0A8V0ZGJ7-1|A0A8V0ZGJ7_CHICK Isoform 1 of FAM3 metabolism regulating signaling molecule D OS=Gallus gallus OX=9031 GN=FAM3D PE=1 SV=1 CANONICAL=A0A8V0ZGJ7-1" }, "locus": { "chromosome": "12", "start_pos": 12059561, "end_pos": 12056099, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050648.1", "url": "https://www.ensembl.org/id/ENSGALT00010050648.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029902.1", "url": "https://www.ensembl.org/id/ENSGALP00010029902.1" } ] } }, { "isoform_ac": "E1C5S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7/entry#E1C5S9-1", "sequence": { "sequence": "MRMTGVIRLLVLLATLLGSWFIVQTYFERSGRAISLRSWLGATSEPMSTPPQPRHKCANKRDCPADHFAFRIISGAANVVGPSICFEDRILMSTVKNNIGRGLNIALVNGKSGQLLKVGSFDMYSGDVTQLETFLQEIKDGTIMLVATYDDAATKMNNKVRALFSALGSRYANQLGFRDNWVFLGAKGLKGKSPFEEHIKNDQKTNKYEGWPELLEMEGCAPRKQD", "length": 226, "header": "tr|E1C5S9-1|A0A8V0ZGJ7_CHICK Computationally mapped isoform of FAM3 metabolism regulating signaling molecule D OS=Gallus gallus OX=9031 GN=FAM3D PE=1 SV=2 CANONICAL=A0A8V0ZGJ7-1" }, "locus": { "chromosome": "12", "start_pos": 12059561, "end_pos": 12056099, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050650.1", "url": "https://www.ensembl.org/id/ENSGALT00010050650.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029904.1", "url": "https://www.ensembl.org/id/ENSGALP00010029904.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416069", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416069", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7" } ], "pmid": "" }, { "name": "negative regulation of insulin secretion", "id": "GO:0046676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGJ7" }, { "id": "PF15711", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ILEI/PANDER", "eco_id": "ECO_0000259", "start_pos": 101, "end_pos": 235, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGM1-1", "uniprot_ac": "A0A8V0ZGM1", "uniprot_id": "A0A8V0ZGM1_CHICK", "mass": { "chemical_mass": 306118.0, "monoisotopic_mass": 306118.0 }, "refseq": {}, "gene_names": [ { "name": "NBEAL1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1" } ] } ], "protein_names": [ { "name": "Neurobeachin-like protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NBEAL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1", "locus": { "chromosome": "7", "start_pos": 13306446, "end_pos": 13381411, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022149", "url": "https://www.ensembl.org/id/ENSGALG00010022149" } ] } } ], "crossref": [ { "id": "cd01201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06071", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06071", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGM1", "url": "https://www.orthodb.org/?gene=A0A8V0ZGM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNQ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZNQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP42", "url": "https://www.orthodb.org/?gene=A0A8V0ZP42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13743", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13743", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13743:SF115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13743:SF115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02138", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02138", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14844", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14844", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZGM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRERLYELWMLYCSKKDPDYLKLWLDSFVSSYEQFLDVDFEKLPTRVDDIPPGISLLPDNILQVLRLQLLQCVQKMSDGLEEQQQALSLLLVKFFIILCRNLANVEEIGMCSYINHVITMTTLYIQQLKSKTKEKEMADQTPIEEFVRHALAFCESLYDPYRNWRQRIAGRILSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLKCCLLHLFGAIVAGGQRNALQAVSPATMEVLMRVLADCDNWDDGSPEEVSRKAELTLKCLTEVVHILLNSSSDQRQVETSTILENYFKLLNSDHSALPKPRRCRQWESRFIALQIQMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKVFQGHLDCLAVSTIQALTAVMHKSPAAKEVFKERIGYAHIYEVLKSLGQPSRELLEELMNMAVEGDHMAVGILGISNVQPLLLLIQWLPELESHDLQIFISNWLRRICCINRQSRATCVNADMVIRIIETLNHHSALHCTCAENLIALLGSLGSQSMGSEELLQLIRLLRTEEPKQAHPYVIPVVRAILAMARKQGMASALQYFNLCHSMAGIAVPSIQKWPGSAFSFNAWLCLDQDQVDPSTASKTGKRKQLYSFFTGSGMGFEAFITCSGVLVVAVCTKREYATVMLPDHCFFDSLWHNITIVHMPGKRPFGQSLVYIYVNGQQKISAPLRFPAMNEPFTSCCIGSAGQRTTTPPPSQIPDPPFSSPIMPHRTSLGGILSPGSWGGMLAKPELITKMISAGTQDSEWGCPTSLEGQLGSVIIFHEALQPPQVKALYLAGPNCLTPWKSQEPEVADLPSKVLLHYTPKACRNPICLDLSANLLHGRLTGNKVVNWDIKDMINCIGGINVLFPLLEQISFLGRQMPEKSVGETLPPEVVTPVEGDWVVLSSAKASEARLEKNIVATFILVIKHFIERHHVNQENLIHSHGVATLGTLLQKVPSILMDVNVLMAVQLLIEQVSVEKNLQLLQQMYQHLLFDFSIWNSGDFPFRIGHIQYLSTIIKDSRRLFRKKYGVQFLLDTLRVYYGSGCKDSDLAPDDLRTIRMSLYGLIKYFLSKGGTHEEIQSIVGYIAATSEEEQLCGILEVLFSLLHSSSAPDQLFLLLFEPGNADILYALLLHQRYSDRVRELVFKIMEEMLKCTKVYERSKHRMRLREVGYSGLGLLLNESSVTISLIKNLLNQVLYADPAVNYKDLLAVVHLAHRSDINMRVVICRKVLHLLHSQLDAAQQISQQLGWQDTLIRLFLKENSEVQIGFRENRADSLREEEKKPPAEELQKYHTDKMEGDKSDTFVSVNGLFDQWSLEDNKSLDVPAHFSAMPLEDASTAEMSFKSEDREELWHSNPSHLSLDLSSVDSYELADVVNQMTDSLPSTPSPVENRKPFSGQPEKELDVISDVGFSAADLSLFENQGGGDNELIQLLTDILLCIMWKGIEKSDDEAWMERGQVFSALTKLGISNELLRPSDEIKLKLLEKMLEWSVTDNRDSKALPTHTENAFRLLLIVQDFLQAEGLVNSNLWTEKLLEELVILMDSLSVWYSAGPEATWFSQVQIQLLLGFIAKDNLQVCAMAAAKLNTLLQTKVIESQPEACYLLGKLEGILSRSIEEKTETYSFLIPLVRTLVSKIYELLFMNLHLPSLPSTNGSPSFFEDFQEYCRSDEWKVYIDKYIIPNMKHYEENSFRHGHEQMALYWKDCYEAFMVNMHKRDRERGESKLKFQEHFVEPFSRKARQENLRYNSMLKQLNSQHTATLRQWRAAQLYLLSERGPWSEMKQHPVHWKLSNVENFSRMRLKLVQNYNFNSHQDASDLRDNLGVYQAQPSSESLLLEVVKQVKVSDLEDDVLELPEEDTAASSNMDEKDEQSQKEKLILSENCELITVIDVIPGRLEVTTQHLYFFDGSVEKEEGVGFDFKWHLSQIREIHLRRYNLRRSALEIFLTDQTNYFLNFNKEVRNKVYSRILSLRSPNISGTRSPQELFKASGLMQKWVNREISNFDYLIQLNTMAGRTYNDLAQYPVFPWILRDYTSEELDLNNPAVFRDLSKPIGVVNEKNAKAVKEKYDNFEDPLGVIDKFHYGTHYSNAAGVMHYLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPNDVKELIPEFFYFPEFLENQNGFNLGQLQISKEAVNDVVLPKWAHSPEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCTYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPQRLSAEEVVQRLTRSDTSTLNLFQHLTELKSFFIEGISDGVPIVKAVVPRNQSRSFMSQGSPEILVTASLNCIIGTHGWLPYDKNISNYFTFIKDTTVTNPKTQRNMSGPFAPGLEITSKLFAVSHDAKLLFSGGHWDNSIRVTSLTKGKLIGQHIRHMDIVTCLAIDYCGIHLISGSRDTTCMIWQIVQQGGVPVGLTPKPLQILYGHTDEVTSVGISTELDMAVSGSRDGTVIIRTIRKGQYMRTLRPPCESSLLLTVPHLAVSWEGHIVVHTSIEGKTTLKDKNALHLYSVNGKHLGSETLKEEVSDMCVTGEYIVMGSLQGFLSIRDLYSLNLSISPLAMRLPIHCISVTKEYSHILVGLEDGKLIIVGVGKPAEMRSGQLSRKLWGSSKRLSQISSGETEYNTQDSK", "length": 2696, "header": "tr|A0A8V0ZGM1-1|A0A8V0ZGM1_CHICK Isoform 1 of Neurobeachin-like protein 2 OS=Gallus gallus OX=9031 GN=NBEAL1 PE=3 SV=1 CANONICAL=A0A8V0ZGM1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1/entry#A0A8V0ZGM1-1", "sequence": { "sequence": "MASRERLYELWMLYCSKKDPDYLKLWLDSFVSSYEQFLDVDFEKLPTRVDDIPPGISLLPDNILQVLRLQLLQCVQKMSDGLEEQQQALSLLLVKFFIILCRNLANVEEIGMCSYINHVITMTTLYIQQLKSKTKEKEMADQTPIEEFVRHALAFCESLYDPYRNWRQRIAGRILSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLKCCLLHLFGAIVAGGQRNALQAVSPATMEVLMRVLADCDNWDDGSPEEVSRKAELTLKCLTEVVHILLNSSSDQRQVETSTILENYFKLLNSDHSALPKPRRCRQWESRFIALQIQMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKVFQGHLDCLAVSTIQALTAVMHKSPAAKEVFKERIGYAHIYEVLKSLGQPSRELLEELMNMAVEGDHMAVGILGISNVQPLLLLIQWLPELESHDLQIFISNWLRRICCINRQSRATCVNADMVIRIIETLNHHSALHCTCAENLIALLGSLGSQSMGSEELLQLIRLLRTEEPKQAHPYVIPVVRAILAMARKQGMASALQYFNLCHSMAGIAVPSIQKWPGSAFSFNAWLCLDQDQVDPSTASKTGKRKQLYSFFTGSGMGFEAFITCSGVLVVAVCTKREYATVMLPDHCFFDSLWHNITIVHMPGKRPFGQSLVYIYVNGQQKISAPLRFPAMNEPFTSCCIGSAGQRTTTPPPSQIPDPPFSSPIMPHRTSLGGILSPGSWGGMLAKPELITKMISAGTQDSEWGCPTSLEGQLGSVIIFHEALQPPQVKALYLAGPNCLTPWKSQEPEVADLPSKVLLHYTPKACRNPICLDLSANLLHGRLTGNKVVNWDIKDMINCIGGINVLFPLLEQISFLGRQMPEKSVGETLPPEVVTPVEGDWVVLSSAKASEARLEKNIVATFILVIKHFIERHHVNQENLIHSHGVATLGTLLQKVPSILMDVNVLMAVQLLIEQVSVEKNLQLLQQMYQHLLFDFSIWNSGDFPFRIGHIQYLSTIIKDSRRLFRKKYGVQFLLDTLRVYYGSGCKDSDLAPDDLRTIRMSLYGLIKYFLSKGGTHEEIQSIVGYIAATSEEEQLCGILEVLFSLLHSSSAPDQLFLLLFEPGNADILYALLLHQRYSDRVRELVFKIMEEMLKCTKVYERSKHRMRLREVGYSGLGLLLNESSVTISLIKNLLNQVLYADPAVNYKDLLAVVHLAHRSDINMRVVICRKVLHLLHSQLDAAQQISQQLGWQDTLIRLFLKENSEVQIGFRENRADSLREEEKKPPAEELQKYHTDKMEGDKSDTFVSVNGLFDQWSLEDNKSLDVPAHFSAMPLEDASTAEMSFKSEDREELWHSNPSHLSLDLSSVDSYELADVVNQMTDSLPSTPSPVENRKPFSGQPEKELDVISDVGFSAADLSLFENQGGGDNELIQLLTDILLCIMWKGIEKSDDEAWMERGQVFSALTKLGISNELLRPSDEIKLKLLEKMLEWSVTDNRDSKALPTHTENAFRLLLIVQDFLQAEGLVNSNLWTEKLLEELVILMDSLSVWYSAGPEATWFSQVQIQLLLGFIAKDNLQVCAMAAAKLNTLLQTKVIESQPEACYLLGKLEGILSRSIEEKTETYSFLIPLVRTLVSKIYELLFMNLHLPSLPSTNGSPSFFEDFQEYCRSDEWKVYIDKYIIPNMKHYEENSFRHGHEQMALYWKDCYEAFMVNMHKRDRERGESKLKFQEHFVEPFSRKARQENLRYNSMLKQLNSQHTATLRQWRAAQLYLLSERGPWSEMKQHPVHWKLSNVENFSRMRLKLVQNYNFNSHQDASDLRDNLGVYQAQPSSESLLLEVVKQVKVSDLEDDVLELPEEDTAASSNMDEKDEQSQKEKLILSENCELITVIDVIPGRLEVTTQHLYFFDGSVEKEEGVGFDFKWHLSQIREIHLRRYNLRRSALEIFLTDQTNYFLNFNKEVRNKVYSRILSLRSPNISGTRSPQELFKASGLMQKWVNREISNFDYLIQLNTMAGRTYNDLAQYPVFPWILRDYTSEELDLNNPAVFRDLSKPIGVVNEKNAKAVKEKYDNFEDPLGVIDKFHYGTHYSNAAGVMHYLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPNDVKELIPEFFYFPEFLENQNGFNLGQLQISKEAVNDVVLPKWAHSPEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCTYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPQRLSAEEVVQRLTRSDTSTLNLFQHLTELKSFFIEGISDGVPIVKAVVPRNQSRSFMSQGSPEILVTASLNCIIGTHGWLPYDKNISNYFTFIKDTTVTNPKTQRNMSGPFAPGLEITSKLFAVSHDAKLLFSGGHWDNSIRVTSLTKGKLIGQHIRHMDIVTCLAIDYCGIHLISGSRDTTCMIWQIVQQGGVPVGLTPKPLQILYGHTDEVTSVGISTELDMAVSGSRDGTVIIRTIRKGQYMRTLRPPCESSLLLTVPHLAVSWEGHIVVHTSIEGKTTLKDKNALHLYSVNGKHLGSETLKEEVSDMCVTGEYIVMGSLQGFLSIRDLYSLNLSISPLAMRLPIHCISVTKEYSHILVGLEDGKLIIVGVGKPAEMRSGQLSRKLWGSSKRLSQISSGETEYNTQDSK", "length": 2696, "header": "tr|A0A8V0ZGM1-1|A0A8V0ZGM1_CHICK Isoform 1 of Neurobeachin-like protein 2 OS=Gallus gallus OX=9031 GN=NBEAL1 PE=3 SV=1 CANONICAL=A0A8V0ZGM1-1" }, "locus": { "chromosome": "7", "start_pos": 13380661, "end_pos": 13307617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053909.1", "url": "https://www.ensembl.org/id/ENSGALT00010053909.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032463.1", "url": "https://www.ensembl.org/id/ENSGALP00010032463.1" } ] } }, { "isoform_ac": "A0A8V0ZNQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1/entry#A0A8V0ZNQ0-1", "sequence": { "sequence": "MTGKTKLNREKDPDYLKLWLDSFVSSYEQFLDVDFEKLPTRVDDIPPGISLLPDNILQVLRLQLLQCVQKMSDGLEEQQQALSLLLVKFFIILCRNLANVEEIGMCSYINHVITMTTLYIQQLKSKTKEKEMADQTPIEEFVRHALAFCESLYDPYRNWRQRIAGRILSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLKCCLLHLFGAIVAGGQRNALQAVSPATMEVLMRVLADCDNWDDGSPEEVSRKAELTLKCLTEVVHILLNSSSDQRQVETSTILENYFKLLNSDHSALPKPRRCRQWESRFIALQIQMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKVFQGHLDCLAVSTIQALTAVMHKSPAAKEVFKERIGYAHIYEVLKSLGQPSRELLEELMNMAVEGDHMAVGILGISNVQPLLLLIQWLPELESHDLQIFISNWLRRICCINRQSRATCVNADMVIRIIETLNHHSALHCTCAENLIALLGSLGSQSMGSEELLQLIRLLRTEEPKQAHPYVIPVVRAILAMARKQGMASALQYFNLCHSMAGIAVPSIQKWPGSAFSFNAWLCLDQDQVDPSTASKTGKRKQLYSFFTGSGMGFEAFITCSGVLVVAVCTKREYATVMLPDHCFFDSLWHNITIVHMPGKRPFGQSLVYIYVNGQQKISAPLRFPAMNEPFTSCCIGSAGQRTTTPPPSQIPDPPFSSPIMPHRTSLGGILSPGSWGGMLAKPELITKMISAGTQDSEWGCPTSLEGQLGSVIIFHEALQPPQVKALYLAGPNCLTPWKSQEPEVADLPSKVLLHYTPKACRNPICLDLSANLLHGRLTGNKVVNWDIKDMINCIGGINVLFPLLEQISFLGRQMPEKSVGETLPPEVVTPVEGDWVVLSSAKASEARLEKNIVATFILVIKHFIERHHVNQENLIHSHGVATLGTLLQKVPSILMDVNVLMAVQLLIEQVSVEKNLQLLQQMYQHLLFDFSIWNSGDFPFRIGHIQYLSTIIKDSRRLFRKKYGVQFLLDTLRVYYGSGCKDSDLAPDDLRTIRMSLYGLIKYFLSKGGTHEEIQSIVGYIAATSEEEQLCGILEVLFSLLHSSSAPDQLFLLLFEPGNADILYALLLHQRYSDRVRELVFKIMEEMLKCTKVYERSKHRMRLREVGYSGLGLLLNESSVTISLIKNLLNQVLYADPAVNYKDLLAVVHLAHRSDINMRVVICRKVLHLLHSQLDAAQQISQQLGWQDTLIRLFLKENSEVQIGFRENRADSLREEEKKPPAEELQKYHTDKMEGDKSDTFVSVNGLFDQWSLEDNKSLDVPAHFSAMPLEDASTAEMSFKSEDREELWHSNPSHLSLDLSSVDSYELADVVNQMTDSLPSTPSPVENRKPFSGQPEKELDVISDVGFSAADLSLFENQGGGDNELIQLLTDILLCIMWKGIEKSDDEAWMERGQVFSALTKLGISNELLRPSDEIKLKLLEKMLEWSVTDNRDSKALPTHTENAFRLLLIVQDFLQAEGLVNSNLWTEKLLEELVILMDSLSVWYSAGPEATWFSQVQIQLLLGFIAKDNLQVCAMAAAKLNTLLQTKVIESQPEACYLLGKLEGILSRSIEEKTETYSFLIPLVRTLVSKIYELLFMNLHLPSLPSTNGSPSFFEDFQEYCRSDEWKVYIDKYIIPNMKHYEENSFRHGHEQMALYWKDCYEAFMVNMHKRDRERGESKLKFQEHFVEPFSRKARQENLRYNSMLKQLNSQHTATLRQWRAAQLYLLSERGPWSEMKQHPVHWKLSNVENFSRMRLKLVQNYNFNSHQDASDLRDNLGVYQAQPSSESLLLEVVKQVKVSDLEDDVLELPEEDTAASSNMDEKDEQSQKEKLILSENCELITVIDVIPGRLEVTTQHLYFFDGSVEKEEGVGFDFKWHLSQIREIHLRRYNLRRSALEIFLTDQTNYFLNFNKEVRNKVYSRILSLRSPNISGTRSPQELFKASGLMQKWVNREISNFDYLIQLNTMAGRTYNDLAQYPVFPWILRDYTSEELDLNNPAVFRDLSKPIGVVNEKNAKAVKEKYDNFEDPLGVIDKFHYGTHYSNAAGVMHYLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPNDVKELIPEFFYFPEFLENQNGFNLGQLQISKEAVNDVVLPKWAHSPEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCTYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPQRLSAEEVVQRLTRSDTSTLNLFQHLTELKSFFIEGISDGVPIVKAVVPRNQSRSFMSQGSPEILVTASLNCIIGTHGWLPYDKNISNYFTFIKDTTVTNPKTQRNMSGPFAPGLEITSKLFAVSHDAKLLFSGGHWDNSIRVTSLTKGKLIGQHIRHMDIVTCLAIDYCGIHLISGSRDTTCMIWQIVQQGGVPVGLTPKPLQILYGHTDEVTSVGISTELDMAVSGSRDGTVIIRTIRKGQYMRTLRPPCESSLLLTVPHLAVSWEGHIVVHTSIEGKTTLKDKNALHLYSVNGKHLGSETLKEEVSDMCVTGEYIVMGSLQGFLSIRDLYSLNLSISPLAMRLPIHCISVTKEYSHILVGLEDGKLIIVGVGKPAEMRSGQLSRKLWGSSKRLSQISSGETEYNTQDSK", "length": 2689, "header": "tr|A0A8V0ZNQ0-1|A0A8V0ZNQ0_CHICK Computationally mapped isoform of Neurobeachin-like protein 2 OS=Gallus gallus OX=9031 GN=NBEAL1 PE=3 SV=1 CANONICAL=A0A8V0ZGM1-1" }, "locus": { "chromosome": "7", "start_pos": 13373995, "end_pos": 13307617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053888.1", "url": "https://www.ensembl.org/id/ENSGALT00010053888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032447.1", "url": "https://www.ensembl.org/id/ENSGALP00010032447.1" } ] } }, { "isoform_ac": "A0A8V0ZP42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1/entry#A0A8V0ZP42-1", "sequence": { "sequence": "MVPRVAMSMQAQKDPDYLKLWLDSFVSSYEQFLDVDFEKLPTRVDDIPPGISLLPDNILQVLRLQLLQCVQKMSDGLEEQQQALSLLLVKFFIILCRNLANVEEIGMCSYINHVITMTTLYIQQLKSKTKEKEMADQTPIEEFVRHALAFCESLYDPYRNWRQRIAGRILSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLKCCLLHLFGAIVAGGQRNALQAVSPATMEVLMRVLADCDNWDDGSPEEVSRKAELTLKCLTEVVHILLNSSSDQRQVETSTILENYFKLLNSDHSALPKPRRCRQWESRFIALQIQMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKVFQGHLDCLAVSTIQALTAVMHKSPAAKEVFKERIGYAHIYEVLKSLGQPSRELLEELMNMAVEGDHMAVGILGISNVQPLLLLIQWLPELESHDLQIFISNWLRRICCINRQSRATCVNADMVIRIIETLNHHSALHCTCAENLIALLGSLGSQSMGSEELLQLIRLLRTEEPKQAHPYVIPVVRAILAMARKQGMASALQYFNLCHSMAGIAVPSIQKWPGSAFSFNAWLCLDQDQVDPSTASKTGKRKQLYSFFTGSGMGFEAFITCSGVLVVAVCTKREYATVMLPDHCFFDSLWHNITIVHMPGKRPFGQSLVYIYVNGQQKISAPLRFPAMNEPFTSCCIGSAGQRTTTPPPSQIPDPPFSSPIMPHRTSLGGILSPGSWGGMLAKPELITKMISAGTQDSEWGCPTSLEGQLGSVIIFHEALQPPQVKALYLAGPNCLTPWKSQEPEVADLPSKVLLHYTPKACRNPICLDLSANLLHGRLTGNKVVNWDIKDMINCIGGINVLFPLLEQISFLGRQMPEKSVGETLPPEVVTPVEGDWVVLSSAKASEARLEKNIVATFILVIKHFIERHHVNQENLIHSHGVATLGTLLQKVPSILMDVNVLMAVQLLIEQVSVEKNLQLLQQMYQHLLFDFSIWNSGDFPFRIGHIQYLSTIIKDSRRLFRKKYGVQFLLDTLRVYYGSGCKDSDLAPDDLRTIRMSLYGLIKYFLSKGGTHEEIQSIVGYIAATSEEEQLCGILEVLFSLLHSSSAPDQLFLLLFEPGNADILYALLLHQRYSDRVRELVFKIMEEMLKCTKVYERSKHRMRLREVGYSGLGLLLNESSVTISLIKNLLNQVLYADPAVNYKDLLAVVHLAHRSDINMRVVICRKVLHLLHSQLDAAQQISQQLGWQDTLIRLFLKENSEVQIGFRENRADSLREEEKKPPAEELQKYHTDKMEGDKSDTFVSVNGLFDQWSLEDNKSLDVPAHFSAMPLEDASTAEMSFKSEDREELWHSNPSHLSLDLSSVDSYELADVVNQMTDSLPSTPSPVENRKPFSGQPEKELDVISDVGFSAADLSLFENQGGGDNELIQLLTDILLCIMWKGIEKSDDEAWMERGQVFSALTKLGISNELLRPSDEIKLKLLEKMLEWSVTDNRDSKALPTHTENAFRLLLIVQDFLQAEGLVNSNLWTEKLLEELVILMDSLSVWYSAGPEATWFSQVQIQLLLGFIAKDNLQVCAMAAAKLNTLLQTKVIESQPEACYLLGKLEGILSRSIEEKTETYSFLIPLVRTLVSKIYELLFMNLHLPSLPSTNGSPSFFEDFQEYCRSDEWKVYIDKYIIPNMKHYEENSFRHGHEQMALYWKDCYEAFMVNMHKRDRERGESKLKFQEHFVEPFSRKARQENLRYNSMLKQLNSQHTATLRQWRAAQLYLLSERGPWSEMKQHPVHWKLSNVENFSRMRLKLVQNYNFNSHQDASDLRDNLGVYQAQPSSESLLLEVVKQVKVSDLEDDVLELPEEDTAASSNMDEKDEQSQKEKLILSENCELITVIDVIPGRLEVTTQHLYFFDGSVEKEEGVGFDFKWHLSQIREIHLRRYNLRRSALEIFLTDQTNYFLNFNKEVRNKVYSRILSLRSPNISGTRSPQELFKASGLMQKWVNREISNFDYLIQLNTMAGRTYNDLAQYPVFPWILRDYTSEELDLNNPAVFRDLSKPIGVVNEKNAKAVKEKYDNFEDPLGVIDKFHYGTHYSNAAGVMHYLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPNDVKELIPEFFYFPEFLENQNGFNLGQLQISKEAVNDVVLPKWAHSPEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCTYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPQRLSAEEVVQRLTRSDTSTLNLFQHLTELKSFFIEGISDGVPIVKAVVPRNQSRSFMSQGSPEILVTASLNCIIGTHGWLPYDKNISNYFTFIKDTTVTNPKTQRNMSGPFAPGLEITSKLFAVSHDAKLLFSGGHWDNSIRVTSLTKGKLIGQHIRHMDIVTCLAIDYCGIHLISGSRDTTCMIWQIVQQGGVPVGLTPKPLQILYGHTDEVTSVGISTELDMAVSGSRDGTVIIRTIRKGQYMRTLRPPCESSLLLTVPHLAVSWEGHIVVHTSIEGKTTLKDKNALHLYSVNGKHLGSETLKEEVSDMCVTGEYIVMGSLQGFLSIRDLYSLNLSISPLAMRLPIHCISVTKEYSHILVGLEDGKLIIVGVGKPAEMRSGQLSRKLWGSSKRLSQISSGETEYNTQDSK", "length": 2691, "header": "tr|A0A8V0ZP42-1|A0A8V0ZP42_CHICK Computationally mapped isoform of Neurobeachin-like protein 2 OS=Gallus gallus OX=9031 GN=NBEAL1 PE=3 SV=1 CANONICAL=A0A8V0ZGM1-1" }, "locus": { "chromosome": "7", "start_pos": 13372206, "end_pos": 13307617, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053900.1", "url": "https://www.ensembl.org/id/ENSGALT00010053900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032456.1", "url": "https://www.ensembl.org/id/ENSGALP00010032456.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1399, "start_aa": "Thr", "end_pos": 1399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1399", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "myeloid cell differentiation", "id": "GO:0030099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030099", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1333, "end_pos": 1335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1667, "end_pos": 1669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1809, "end_pos": 1811, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1989, "end_pos": 1991, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2335, "end_pos": 2337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2369, "end_pos": 2371, "annotation": "n_glycosylation_sequon" }, { 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-like 7 (bone marrow stromal cell-derived)", "type": "synonym", "evidence": [ { "id": "NP_001186677", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186677" } ] }, { "name": "ubiquitin-like protein 7", "type": "synonym", "evidence": [ { "id": "NP_001186677", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186677" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01015517.1, HAEL01004088.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On Sep 23, 2021 this sequence version replaced NP_001186677.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001186677", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186677" } ] }, { "annotation": "Interferon-stimulated protein that positively regulates RNA virus-triggered innate immune signaling. Mechanistically, promotes 'Lys-27'-linked polyubiquitination of MAVS through TRIM21 leading to enhanced the IFN signaling pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60#function" }, { "database": "UniProtKB", "id": "ARBA00057016", "url": "https://www.uniprot.org/uniprotkb/ARBA00057016#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBL7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60", "locus": { "chromosome": "10", "start_pos": 2548816, "end_pos": 2543670, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021170", "url": "https://www.ensembl.org/id/ENSGALG00010021170" } ] } } ], "crossref": [ { "id": "A0A8V0ZI60", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZI60", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01815", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01815", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14326", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14326", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415297", "url": "https://www.ncbi.nlm.nih.gov/gene/415297", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415297", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415297", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HAINLLM", "url": "https://omabrowser.org/oma/group/HAINLLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGS4", "url": "https://www.orthodb.org/?gene=A0A8V0ZGS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI60", "url": "https://www.orthodb.org/?gene=A0A8V0ZI60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10677:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10677:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186677", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186677", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSEWHIAVKLADQPLAPKSILRLPETELGECPLSGCSISHLKQLITGKLQESVPDPELIDLIYCGRKLRDDQTLDFYGIQSGSTVHVLRKSWPEPDQKPEPVDKVAAVREFRVLHTALHSSPAYRDAVFKMLGNKESLDQIIVATPGLSSDPVALGVLQDKDLFSVFADPNMLDTLIPAHPALVNAIVLVLHSVAGSTPLPAPETSSRGMSSGSYRDMPGGFLFEGLSDDEDDFHQSTRSTPSSSTSGSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSSVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIHDDELSLRALQATGGDIQAALELIFAGGAP", "length": 380, "header": "tr|A0A8V0ZI60-1|A0A8V0ZI60_CHICK Isoform 1 of Ubiquitin-like protein 7 OS=Gallus gallus OX=9031 GN=UBL7 PE=1 SV=1 CANONICAL=A0A8V0ZI60-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60/entry#A0A8V0ZGS4-1", "sequence": { "sequence": "MAVSEWHIAVKLADQPLAPKSILRLPETELGECPLSGCSISHLKQLITGKLQESVPDPELIDLIYCGRKLRDDQTLDFYGIQSGSTVHVLRKSWPEPDQKPEPVDKVAAVREFRVLHTALHSSPAYRDAVFKMLGNKESLDQIIVATPGLSSDPVALGVLQDKDLFSVFADPNMLDTLIPAHPALVNAIVLVLHSVAGSTPLPAPETSSRGMSSGSYRDMPGGFLFEGLSDDEDDFHQSTRSTPSSSTSGSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSSVQSGTPITNDLFSQALQHALQASGQPSLQVSVSASSFGNP", "length": 346, "header": "tr|A0A8V0ZGS4-1|A0A8V0ZI60_CHICK Computationally mapped isoform of Ubiquitin-like protein 7 OS=Gallus gallus OX=9031 GN=UBL7 PE=1 SV=1 CANONICAL=A0A8V0ZI60-1" }, "locus": { "chromosome": "10", "start_pos": 2547901, "end_pos": 2543948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051287.1", "url": "https://www.ensembl.org/id/ENSGALT00010051287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030478.1", "url": "https://www.ensembl.org/id/ENSGALP00010030478.1" } ] } }, { "isoform_ac": "A0A8V0ZI60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60/entry#A0A8V0ZI60-1", "sequence": { "sequence": "MAVSEWHIAVKLADQPLAPKSILRLPETELGECPLSGCSISHLKQLITGKLQESVPDPELIDLIYCGRKLRDDQTLDFYGIQSGSTVHVLRKSWPEPDQKPEPVDKVAAVREFRVLHTALHSSPAYRDAVFKMLGNKESLDQIIVATPGLSSDPVALGVLQDKDLFSVFADPNMLDTLIPAHPALVNAIVLVLHSVAGSTPLPAPETSSRGMSSGSYRDMPGGFLFEGLSDDEDDFHQSTRSTPSSSTSGSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSSVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIHDDELSLRALQATGGDIQAALELIFAGGAP", "length": 380, "header": "tr|A0A8V0ZI60-1|A0A8V0ZI60_CHICK Isoform 1 of Ubiquitin-like protein 7 OS=Gallus gallus OX=9031 GN=UBL7 PE=1 SV=1 CANONICAL=A0A8V0ZI60-1" }, "locus": { "chromosome": "10", "start_pos": 2548403, "end_pos": 2543948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051284.1", "url": "https://www.ensembl.org/id/ENSGALT00010051284.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030475.1", "url": "https://www.ensembl.org/id/ENSGALP00010030475.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 290, "start_aa": "Thr", "end_pos": 290, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr290", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415297", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415297", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZWS3-1", "protein_name": "Ubiquitin-like protein 7", "gene_name": "Ubl7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRGASGFRQEDQRRKRERERERMSLSDWHLAVKLADQPLAPKSILQLPETELGEYSLGGYSISFLKQLIAGKLQESVPDPELIDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAALREFRVLHTALHSSSSYREAVFKMLNNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIILVLHSVAGSTPMPGADSSSRSMPSSSYRDMPGGFLFDGLSDDEDDFHPSTRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQALQHALQASGQQPSLQSQWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALELIFAGGAP", "length": 404 }, "evidence": [ { "id": "A0A8V0ZI60", "url": "https://omabrowser.org/oma/group/A0A8V0ZI60/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SIE4-1", "protein_name": "Ubiquitin-like protein 7", "gene_name": "UBL7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLSDWHLAVKLADQPLAPKSILRLPEAELGEYSLGGYSISFLKQLIAGKLQESVPDPELIDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAALREFRVLHTALHSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIVLVLHSVAGSTPLPGADTSSRGMPSSSYRDMPGGFLFEGLSDEEDDFHPSARSTPSSSTSSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALELIFAGGAP", "length": 380 }, "evidence": [ { "id": "A0A8V0ZI60", "url": "https://omabrowser.org/oma/group/A0A8V0ZI60/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HEH6-1", "protein_name": "Ubiquitin-like protein 7", "gene_name": "Ubl7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLSDWHLAVKLADQPLAPKSILQLPETEVGEYSLGAYSISFLKQLIAGKLQESVPDPELIDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAALREFRVLHTALHSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPSMLDTLVPAHPALVNAIILVLHSVAGSTPMPGADSSSRSMPSSSYRDMPGGFLFDGLSDDEDDFHPSTRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVPSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALELIFAGGAP", "length": 380 }, "evidence": [ { "id": "A0A8V0ZI60", "url": "https://omabrowser.org/oma/group/A0A8V0ZI60/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q91W67-1", "protein_name": "Ubiquitin-like protein 7", "gene_name": "Ubl7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLSDWHLAVKLADQPLAPKSILQLPETELGEYSLGGYSISFLKQLIAGKLQESVPDPELIDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAALREFRVLHTALHSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIILVLHSVAGSTPMPGADSSSRSMPSSSYRDMPGGFLFDGLSDDEDDFHPSTRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQIQWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALELIFAGGAP", "length": 380 }, "evidence": [ { "id": "A0A8V0ZI60", "url": "https://omabrowser.org/oma/group/A0A8V0ZI60/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96S82-1", "protein_name": "Ubiquitin-like protein 7", "gene_name": "UBL7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLSDWHLAVKLADQPLTPKSILRLPETELGEYSLGGYSISFLKQLIAGKLQESVPDPELIDLIYCGRKLKDDQTLDFYGIQPGSTVHVLRKSWPEPDQKPEPVDKVAAMREFRVLHTALHSSSSYREAVFKMLSNKESLDQIIVATPGLSSDPIALGVLQDKDLFSVFADPNMLDTLVPAHPALVNAIVLVLHSVAGSAPMPGTDSSSRSMPSSSYRDMPGGFLFEGLSDDEDDFHPNTRSTPSSSTPSSRPASLGYSGAAGPRPITQSELATALALASTPESSSHTPTPGTQGHSSGTSPMSSGVQSGTPITNDLFSQALQHALQASGQPSLQSQWQPQLQQLRDMGIQDDELSLRALQATGGDIQAALELIFAGGAP", "length": 380 }, "evidence": [ { "id": "A0A8V0ZI60", "url": "https://omabrowser.org/oma/group/A0A8V0ZI60/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60" } ], "pmid": "" }, { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 333, "end_pos": 377, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZI60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI60" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 92, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 290 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGT0-1", "uniprot_ac": "A0A8V0ZGT0", "uniprot_id": "A0A8V0ZGT0_CHICK", "mass": { "chemical_mass": 24310.0, "monoisotopic_mass": 24310.0 }, "refseq": {}, "gene_names": [ { "name": "LOC776275", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT0" } ] } ], "protein_names": [ { "name": "Transmembrane protein 263", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC776275", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT0", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZGT0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGT0", "database": "AlphaFoldDB", "categories": [] }, { "id": "776275", "url": "https://www.ncbi.nlm.nih.gov/gene/776275", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GGVIWRM", "url": "https://omabrowser.org/oma/group/GGVIWRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGT0", "url": "https://www.orthodb.org/?gene=A0A8V0ZGT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGT6", "url": "https://www.orthodb.org/?gene=A0A8V0ZGT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUJ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZUJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31443", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31443", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15475", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15475", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKCCRTPQTTPRRTAAPPVARPLARAAHPGRPTPLRWRPLTPALPLPAEVAMALPPLGPPSAAAVCVYIGREEPERWGRRGRSRRRRPPALHPLRAVRGETRHEGKGPSIETQMVEDETETTSEDLPPHLREEPPEDASKDHPQQQAGVIWRVTGGLFSITRGAVGATLGGVAWVGSKSLELTKTAVTSVPAAGVGLVKGSVSAVTGGVGAVGSAVAGKVPFAAKKKDKAD", "length": 231, "header": "tr|A0A8V0ZGT0-1|A0A8V0ZGT0_CHICK Isoform 1 of Transmembrane protein 263 OS=Gallus gallus OX=9031 GN=LOC776275 PE=1 SV=1 CANONICAL=A0A8V0ZGT0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT0/entry#A0A8V0ZGT0-1", "sequence": { "sequence": "MKCCRTPQTTPRRTAAPPVARPLARAAHPGRPTPLRWRPLTPALPLPAEVAMALPPLGPPSAAAVCVYIGREEPERWGRRGRSRRRRPPALHPLRAVRGETRHEGKGPSIETQMVEDETETTSEDLPPHLREEPPEDASKDHPQQQAGVIWRVTGGLFSITRGAVGATLGGVAWVGSKSLELTKTAVTSVPAAGVGLVKGSVSAVTGGVGAVGSAVAGKVPFAAKKKDKAD", "length": 231, "header": "tr|A0A8V0ZGT0-1|A0A8V0ZGT0_CHICK Isoform 1 of Transmembrane protein 263 OS=Gallus gallus OX=9031 GN=LOC776275 PE=1 SV=1 CANONICAL=A0A8V0ZGT0-1" }, "locus": { "chromosome": "5", "start_pos": 23717211, "end_pos": 23533442, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053990.1", "url": "https://www.ensembl.org/id/ENSGALT00010053990.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032523.1", "url": "https://www.ensembl.org/id/ENSGALP00010032523.1" } ] } }, { "isoform_ac": "A0A8V0ZGT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT0/entry#A0A8V0ZGT6-1", "sequence": { "sequence": "MVEDETETTSEDLPPHLREEPPEDASKDHPQQQAGVIWRVTGGLFSITRGAVGATLGGVAWVGSKSLELTKTAVTSVPAAGVGLVKGSVSAVTGGVGAVGSAVAGKVPFAAKKKDKAD", "length": 118, "header": "tr|A0A8V0ZGT6-1|A0A8V0ZGT6_CHICK Computationally mapped isoform of Transmembrane protein 263 OS=Gallus gallus OX=9031 GN=LOC776275 PE=1 SV=1 CANONICAL=A0A8V0ZGT0-1" }, "locus": { "chromosome": "5", "start_pos": 23704088, "end_pos": 23533442, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053997.1", "url": "https://www.ensembl.org/id/ENSGALT00010053997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032528.1", "url": "https://www.ensembl.org/id/ENSGALP00010032528.1" } ] } }, { "isoform_ac": "A0A8V0ZUJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT0/entry#A0A8V0ZUJ7-1", "sequence": { "sequence": "MLLQTICYLCLAFLRYLLYSEMVKDASKDHPQQQAGVIWRVTGGLFSITRGAVGATLGGVAWVGSKSLELTKTAVTSVPAAGVGLVKGSVSAVTGGVGAVGSAVAGKVPFAAKKKDKAD", "length": 119, "header": "tr|A0A8V0ZUJ7-1|A0A8V0ZGT0_CHICK Computationally mapped isoform of Transmembrane protein 263 OS=Gallus gallus OX=9031 GN=LOC776275 PE=1 SV=1 CANONICAL=A0A8V0ZGT0-1" }, "locus": { "chromosome": "5", "start_pos": 23634791, "end_pos": 23533442, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053985.1", "url": "https://www.ensembl.org/id/ENSGALT00010053985.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032519.1", "url": "https://www.ensembl.org/id/ENSGALP00010032519.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGT7-1", "uniprot_ac": "A0A8V0ZGT7", "uniprot_id": "A0A8V0ZGT7_CHICK", "mass": { "chemical_mass": 119214.0, "monoisotopic_mass": 119214.0 }, "refseq": { "ac": "XP_040531203", "name": "PH and SEC7 domain-containing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531203" }, "gene_names": [ { "name": "PSD", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT7" } ] }, { "name": "PSD", "type": "synonym", "evidence": [ { "id": "XP_040531203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531203" } ] } ], "protein_names": [ { "name": "PH and SEC7 domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040531203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531203" } ] }, { "name": "Pleckstrin and Sec7 domain containing", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052578.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040531203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531203" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSD", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT7", "locus": { "chromosome": "6", "start_pos": 17708308, "end_pos": 17743539, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021004", "url": "https://www.ensembl.org/id/ENSGALG00010021004" } ] } } ], "crossref": [ { "id": "A0A8V0ZGT7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13295", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13295", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423760", "url": "https://www.ncbi.nlm.nih.gov/gene/423760", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGT7", "url": "https://www.orthodb.org/?gene=A0A8V0ZGT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01369", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01369", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040531203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531203", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"ac": "XP_414755", "name": "dynein axonemal assembly factor 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414755" }, "gene_names": [ { "name": "DNAAF5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1" } ] }, { "name": "DNAAF5", "type": "synonym", "evidence": [ { "id": "XP_414755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414755" } ] } ], "protein_names": [ { "name": "Dynein axonemal assembly factor 5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1/entry#names_and_taxonomy" } ] }, { "name": "HEAT repeat-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZGV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1/entry#names_and_taxonomy" } ] }, { "name": "dynein axonemal assembly factor 5", "type": "synonym", "evidence": [ { "id": "XP_414755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414755" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_414755.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414755", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414755" } ] }, { "annotation": "Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL8#function" }, { "database": "UniProtKB", "id": "ARBA00055740", "url": "https://www.uniprot.org/uniprotkb/ARBA00055740#function" }, { "database": "UniProtKB", "id": "A0A8V0ZGV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAAF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1", "locus": { "chromosome": "14", "start_pos": 2148566, "end_pos": 2127833, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022203", "url": "https://www.ensembl.org/id/ENSGALG00010022203" } ] } } ], "crossref": [ { "id": "A0A8V0ZGV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "416447", "url": "https://www.ncbi.nlm.nih.gov/gene/416447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416447", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416447", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AFQGPWA", "url": "https://omabrowser.org/oma/group/AFQGPWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGV1", "url": "https://www.orthodb.org/?gene=A0A8V0ZGV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUL8", "url": "https://www.orthodb.org/?gene=A0A8V0ZUL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16216:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16216:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24573", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24573", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25757", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25757", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414755", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414755", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAACGAAELAQALSRPLSCLQGPECGRAARLRALEAIRAEVQERPLSSEAVQEVFEAQLVRPLARCLAGDAAERCRELALQLLLHGLSRCERPGEALPVLLPVLAQRLGPPQGAEPCEELRLGLLQLLGLLLRRGGTAVAPYLSDVVGILQAALLDHFAEVRRESCRCAVACAQAVPEHFHMQSESLIKPLMQTISHQHYRVRVDVIQATGTVIQFGNGKSVDDVLSHLAQRLFDEIPKVRQAVTTVIGEWLLHLRDRYSYFHKLIPLLLGSVTDDIPENMTLAWTYWEKVGLQWEKENEEDLKDKMDFSVPPSHYPKGVTRPGLGCRELVSRNLSKVLPGLCHDLTDWVESTRVKASQLLYVLLLHAEDHITQHMELLLRALYQACLDRESEVVRNCVKAAELIGTFVSPKVSLRLITSAFEITPKPSCLMVLAAVIRGSPKEILQPHLSDLGDTLSQAGVCQRSEEVLYMEQLLCCVRALIEVCQEDCQGICLQLMKVLVAVMAVPNSEHLKEKAEETMCSLAEVQQLDGFLYLYKQHILQLLEWVSVSHDSWTCYSPEILQLGVIATHSGPVIGEALHDFILILKTCLQPNKDPQMRLKLFTVLSELLQKANETINSQGLFPSYLEIVIKDILAPNLQWHAGRTAAAIRTTAVSCLWALIHCQMLAPEEILKVKDALMPQIIAAMDEDSKISRLMGCRIVGGILKVCGRQFDEIQLGKTYPEVLKRLDDASADVRLTAAHTLTDWFKCLKDSDVKSAMKSHIEFLYQELLIHLDDQDPDTQSAVLEVLKEGSVLYPELLVREVEVAIHKHRTPAYCNQLLHHIQTTREAA", "length": 833, "header": "tr|A0A8V0ZGV1-1|A0A8V0ZGV1_CHICK Isoform 1 of Dynein axonemal assembly factor 5 OS=Gallus gallus OX=9031 GN=DNAAF5 PE=1 SV=1 CANONICAL=A0A8V0ZGV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1/entry#A0A8V0ZGV1-1", "sequence": { "sequence": "MAACGAAELAQALSRPLSCLQGPECGRAARLRALEAIRAEVQERPLSSEAVQEVFEAQLVRPLARCLAGDAAERCRELALQLLLHGLSRCERPGEALPVLLPVLAQRLGPPQGAEPCEELRLGLLQLLGLLLRRGGTAVAPYLSDVVGILQAALLDHFAEVRRESCRCAVACAQAVPEHFHMQSESLIKPLMQTISHQHYRVRVDVIQATGTVIQFGNGKSVDDVLSHLAQRLFDEIPKVRQAVTTVIGEWLLHLRDRYSYFHKLIPLLLGSVTDDIPENMTLAWTYWEKVGLQWEKENEEDLKDKMDFSVPPSHYPKGVTRPGLGCRELVSRNLSKVLPGLCHDLTDWVESTRVKASQLLYVLLLHAEDHITQHMELLLRALYQACLDRESEVVRNCVKAAELIGTFVSPKVSLRLITSAFEITPKPSCLMVLAAVIRGSPKEILQPHLSDLGDTLSQAGVCQRSEEVLYMEQLLCCVRALIEVCQEDCQGICLQLMKVLVAVMAVPNSEHLKEKAEETMCSLAEVQQLDGFLYLYKQHILQLLEWVSVSHDSWTCYSPEILQLGVIATHSGPVIGEALHDFILILKTCLQPNKDPQMRLKLFTVLSELLQKANETINSQGLFPSYLEIVIKDILAPNLQWHAGRTAAAIRTTAVSCLWALIHCQMLAPEEILKVKDALMPQIIAAMDEDSKISRLMGCRIVGGILKVCGRQFDEIQLGKTYPEVLKRLDDASADVRLTAAHTLTDWFKCLKDSDVKSAMKSHIEFLYQELLIHLDDQDPDTQSAVLEVLKEGSVLYPELLVREVEVAIHKHRTPAYCNQLLHHIQTTREAA", "length": 833, "header": "tr|A0A8V0ZGV1-1|A0A8V0ZGV1_CHICK Isoform 1 of Dynein axonemal assembly factor 5 OS=Gallus gallus OX=9031 GN=DNAAF5 PE=1 SV=1 CANONICAL=A0A8V0ZGV1-1" }, "locus": { "chromosome": "14", "start_pos": 2147586, "end_pos": 2127841, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054012.1", "url": "https://www.ensembl.org/id/ENSGALT00010054012.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032543.1", "url": "https://www.ensembl.org/id/ENSGALP00010032543.1" } ] } }, { "isoform_ac": "A0A8V0ZUL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1/entry#A0A8V0ZUL8-1", "sequence": { "sequence": "MKREQKLIVFLCVHFLGPVIGEALHDFILILKTCLQPNKDPQMRLKLFTVLSELLQKANETINSQGLFPSYLEIVIKDILAPNLQWHAGRTAAAIRTTAVSCLWALIHCQMLAPEEILKVKDALMPQIIAAMDEDSKISRLMGCRIVGGILKVCGRQFDEIQLGKTYPEVLKRLDDASADVRLTAAHTLTDWFKCLKDSDVKSAMKSHIEFLYQELLIHLDDQDPDTQSAVLEVLKEGSVLYPELLVREVEVAIHKHRTPAYCNQLLHHIQTTREAA", "length": 277, "header": "tr|A0A8V0ZUL8-1|A0A8V0ZGV1_CHICK Computationally mapped isoform of Dynein axonemal assembly factor 5 OS=Gallus gallus OX=9031 GN=DNAAF5 PE=1 SV=1 CANONICAL=A0A8V0ZGV1-1" }, "locus": { "chromosome": "14", "start_pos": 2147586, "end_pos": 2141766, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054009.1", "url": "https://www.ensembl.org/id/ENSGALT00010054009.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032539.1", "url": "https://www.ensembl.org/id/ENSGALP00010032539.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416447", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416447", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LDA6-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "Dnaaf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPAEAEVAAGFAEADEAAELTRALGRLLPGLETESKLGRRRALEALEHALEEAVRPGTDSAAFQGPWARLLLPRLLRLLTDPAEGCRALAAHLLDLGLRRAARPRDALPRLLPALTARLARPESTRPPPEPCEELRLALVQLLHLAVDLGGAALAPHLDDAVRALRGALLDPFAAVRREGCECAAALARAIPEHFHMQSESLIGPLMQTISHQHWKVRVAVIEATGTVIQFGNGNSVDDVLSHFAQRLFDDVPQVRQAVTSVVGGWLLNLRDRYSFFHKLTPLLLSSFSDEMPEVRQTATSLWEKVGLQWQEENEADLKDKLDFASPPPPNYPEHESRPGLGCRELVFRNLSKVLPAICHDITDWVVGTRLKAAQLLPVLLLHAEDHITQHLEIVLRTLHQACTDEEKAVVSSCVRAAELIGTFVSPEVFLKLILAMLKKAPSASGLLILASVIRGCPRNALQPHLKVIATELAQEHICQGSENNSYLEHLLLCVQTLLSVCQEDCCAASLQLSEVLVTIMAVSDAVSLEKKAQKTMDTLAEVEDIPSSQDLYRKHLGALLERLTASHGEWTVHSVQLLKFTVLLTQAGPAVGEALQHVIPTLRACLQPTTDPHMRLKLFSILSSLLLRPKDTVDSQGQFHGYLDMVINDILAPNLQWHAGRTAAAIRTATISCLWALISSDILSAKQVQEAQETLMPQVLATLEDDSQTTRLISCRIISRFLKNSGDTMEPEKFLKVYPELLKRLDDVSNDVRMAAASALLTWLKCIESVDGKSAYQSSVQFLYRELLVHLDDPESAIQDTVLEVLKEGSVLFPDVLVRETEAVVHKHRSATYCEQLLQHMQTMAAAR", "length": 851 }, "evidence": [ { "id": "A0A8V0ZGV1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGV1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B9EJR8-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "Dnaaf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPAEAEVAAAPGLTEAAEAAELTRALSRLLPGLETESKLGRRRALEALEQVLEEAVRPGADSAAFQGPWARLLLPRLLRLLSDPAEGCRALAAHLLDLGLRRAARPRDALPRLLPALSARLARPELARPPPEPCEELRLALVQLLHLAVDLGGAALAPHLDDAVRALRAALLDPFAAVRREGCECAAALARATPEHFHMQSESLIGPLMQTISHQHWKVRVAVIEATGTVIQFGSGNSVDDVLSHFAQRLFDDVPQVRQAVTSVVGGWLLNLRDRYSFLHKLTPLLLSSFSDEMPEIRQTATSLWEKVGLQWQQENEADLKDKLDFASPPPPNYPEHESRPGLGCRELVFRNLSKVLPAICHDITDWVVGTRVKAAQLLPVLLLHAEDHITQHLEIVLRTLHQACTDEEKAVVGSCIRAAELIGTFVSPEVFLKLILAMLKKAPSASGLLILASVIRGCPRNALQPHVTVIATELAQEHICQGSENNLYLEHLLLCVQALLSVCQEDCRAASLQFLEVLVTIMAVSDAVGLEKKAQKTMDTLAEVEDIPSSQDLYRKHVGALLERLTASHGEWAVHSVQLLKFTVLLTQAGPAVGEALQHVIPTLRACLQPSTDPHMRLKLFSILSMMLLRPKDTVDSQGQFRGYLDMVINDILAPNLQWHAGRTAAAIRTAAISCLWALISSDILSAKQVQEAQETLMPQVLATLEDDSQTTRLMSCRIINMFLKNSGDTMEPEKFLKVYPELLKRLDDVSNDVRMAAASALLTWLKCIESLDGKSAYQSSVQFLYRELLVHLDDPESAIQDTVLEVLKEGSVLFPDVLVRETEAVVHKHRSATYCEQLLQHMQTMAAAR", "length": 853 }, "evidence": [ { "id": "A0A8V0ZGV1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGV1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1RIY8-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "DNAAF5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAALVAAEAAVTRGPAEAAEAAEAAELSRVLSRLLPGLEADNKLGRRRALEALQRELEAARPEAPDADPAAAAAAFQGPWARLLLPRLLRCLTDPAEGCRALAVHLLDLGLRRAARPCDALPRLLPALAARLACPEPARRPPPEPCEELRLALVQLLGLAVRLGGTALAPHLDDAVRVLRSTLLDPFAAVRRESCECAAGLARATPDHFHMQSESLIGPLMQTVSHQHWKVRVAVIEATGAVIQFGSGKSVDDVLPHFAQRLFDDVPQVRRAVTRVVGGWLLDLRDRYSFFHKLIPLLLSGFDDDIPDIAHEATSLWEKVGLQWQTENEEDLKDKLDFASPPPAHHPSPERRPGLGCRELVFRNLAKILPAICHDITDWVAGTRVKSAQLLAVLLLHAEDHATQHLEPILRTLLHACADEEGAVVRSCISCAELIGAFVSPEVFLKLILTTLRKSPSAPGLLVLASVVRGCPREALRPHVKVIATELAQAHICQGPENPVYGERLLLCVQALVAGSREDCREAALPLLEVLVTVLALWGATGLGDKVQETLAALAAAEGVDGSQDLFREHLGPLLEWVAASHRDWTVHSAEVLLLDVVVTHSGPALGEALPQLVPILRSCLQPARDPALRLQLFSTLTRVLLRAQEAADARGQLRGCLDTVLKDILVPNLQWHAGRTAAAIRTAAVSCLWALVSSGVLSDKQVQEVQETLMPQVLTTLEEDSQTARLLSCRIVGVFLKASDGATEPDKFIKIYPELLKRLDDVSNEVRLAATSTLVTWLECIRNEAGQCCYRSSVQHLYRELLVYLDDPERAVQDAVLEALKAGSVLFPDVLVRETEAALHRHRSPAYCEQLLRHLQAAPPAQ", "length": 863 }, "evidence": [ { "id": "A0A8V0ZGV1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGV1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3N314-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "DNAAF5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALVAPEAAAPQGPTEAGETTEAAELSRSLSRLLPGLEADSKLGRRRALEALQRVLEAAQPEAPDADPDAAAAAFQGPWVHLLLPRLLRRLTDPAEGCRALAVHLLGLGLRRAARPRDALPRLLPALAARLASPEPARRPPPEACEELRLALVQLLGLAVRLTGAAFAPHLDDAVRALRCTLLDPFAAVRRESCECAAGLARATPDHFHMQSESLIGPLMQSISHQHWKVRVAVIEATGAAIQFGSGKSVDDVLPHFAQRLFDDVPQVRQAVMRVVGGWLLSLRDRYSFFHKLIPLLLSGFHDEIPEIASEASSLWERVGLQWQTENEEDLKDKLDFASPPPAHHPSPGSRPGLGCRELVFRNLSKILPAVCHDIDDWVAGTRVKSAQLLAVLLLHAEDHVTQHLEPVLRALLRACADEEAAVVSSCTRSAELVGTFVSPEVFLKLILSTLRKSPSPSGLLVLASLIQGCPREALRPHVKVIATELAQAHICQGSENRLYGERLLQCVQAVVSAGREDCRGAGEPLLEVLVTVLALWGPAGLSDKVQETLAALAAVEGMDGSQDLFRARVSPLLEWLAASHRDWTGHSVELLQLDVVLSHSGPALGEALPQLVPILRSCLQPARDPAMRLKLFSTLTGVLLGAPETVDSQGQLHGYLDTLVQDIFVPNLQWHAGRTAAAIRTAAVSCLWALVSSGGLSDGQIQDMQETLMPQILTTLEEDSQMTRLISCQIINLFLKTSNGVIDPDKFIKIYPELLKRLDDVSDDVRLAATSALVTWLQRVQSEASKCCYQSSVRHLYRELLVYLDDPEHAVQDAVLEALKAGSVLFPDLLVKETEAVLHKHRSPTYCEQLLQHLQALPPAQ", "length": 863 }, "evidence": [ { "id": "A0A8V0ZGV1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGV1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86Y56-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "DNAAF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALGVAEAVAAPHPAEGAETAEAVELSRALSRLLPGLEADSKPGRRRALEALRRALEEPGPAADPTAFQGPWARLLLPRLLRCLSDPAEGCRALAVHLLDLGLRRAARPRDALPRLLPALAARLAGPVPARRPPEACEELRLALVQLLGLAVDLCGAALAPHLDDALRALRCSLLDPFAAVRRESCSCAAALAQATPDHFHMQSESLIGPLMQTISHQHWKVRVAAIEATGAVIHFGNGKSVDDVLSHFAQRLFDDVPQVRRAVASVVGGWLLCLRDRYSFFHKLIPLLLSSLNDEVPEVRQLAASLWEDVGLQWQKENEEDLKDKLDFAPPTPPHYPPHERRPVLGCRELVFRNLSKILPALCHDITDWVVGTRVKSAQLLPVLLLHAEDHATQHLEVVLRTLFQACTDEEAAVVQSCTRSAELVGTFVSPEVFLKLILSTLKKTPSASGLLVLASAMRGCPREALQPHLAAIATELAQAHICQASENDLYLERLLLCVQALVSVCHEDCGVASLQLLDVLLTIVALAGATGLRDKAQETMDSLAMVEGVSSCQDLYRKHIGPLLERVTASHLDWTAHSPELLQFSVIVAQSGPALGEALPHVVPTLRACLQPSQDPQMRLKLFSILSTVLLRATDTINSQGQFPSYLETVTKDILAPNLQWHAGRTAAAIRTAAVSCLWALTSSEVLSAEQIRDVQETLMPQVLTTLEEDSKMTRLISCRIINTFLKTSGGMTDPEKLIRIYPELLKRLDDVSNDVRMAAASTLVTWLQCVKGANAKSYYQSSVQYLYRELLVHLDDPERAIQDAILEVLKEGSGLFPDLLVRETEAVIHKHRSATYCEQLLQHVQAVPATQ", "length": 855 }, "evidence": [ { "id": "A0A8V0ZGV1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGV1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8INF7-1", "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "Dnaaf5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGFDIDSQKICSDLESSDRRLKTTVLDELLDKCKEATNSESADKIADVFDKLYLHLLKCYEDRFESVRSKAIQVVSAFLSSLPPTDFHLMNVVSTLAERMGKAETVEPSEEIRLLYIAQLNLMICLYEKMENVGVFRECYPLVVKILIKSIKDDYPVVQREGCSAVVTLSRLADTQEFRPFTESILLPLYTMLNHKHAQARISAIQAIARLSLHMDASGDAMRRLFNEVSPLLMDTMPLVRREVGQMGILMLMELLDRYSFFERILPLVLCCLKDESPEVLNHIYPQWLKCGIQYFNENEAELSQQEISDLPVENYPKDVKRPTIGCRGLVQRSLRLLQLITRETSDWKDNVRLHALKLLYQFVLHAEAAMTAKFFEIYGDLAHACIDHVAEVNAEAAKVADLMGRLLSYDAWIDHGFDGLERNARESYMRCFYHMFTASLGGTYEQLMRLAKLLRCTDYSHTLKPGFQHYILKLLNTIVDKTLKINAGQNELEDLYESVYVCAIKVMALSSSLENVGDEDVNFGQTLIEKMVKLLNTSVPKIHERWFHLALQDVINLDAALEDNAEPVMLLNGLINMCHIRATYVHDLIEKVKIVFQHCCDSAQVKIFSSLSLATLFWSKTMNVERESSTQMLSEFVSQIVEPYLTWKAGSNAEAMRSLAMATLCALAQGAESESVEVLPSLAKYMPSLLEDRNVTTRHYAIKAVVYFREMSVEDLKPLAYATMQRMDDPSAGIRILAALAMGKLKPKFAETDTEENYEKEVWDAIVKRAMDLLLLYHESPEKDMRAAVAVTLKVLAKSHPEAWEERYQRALPMAQKKDLLTELYDKLTINEDSHTEVTSASQD", "length": 845 }, "evidence": [ { "id": "A0A8V0ZGV1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGV1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1" } ], "pmid": "" }, { "name": "outer dynein arm assembly", "id": "GO:0036158", "url": 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} ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 615, "end_pos": 617, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV1" }, { "id": "PF24573", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24573" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dynein axonemal assembly factor 5 HEAT-repeat", "eco_id": "ECO_0000259", "start_pos": 314, "end_pos": 507, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZGV1", "database": "UniProtKB", 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"MPPPGIWHLPGQQECGTHSPPSAPASHRCPPPAGPPLAPLIQVGAGKVHGHPTVTEPWVPAVLSLAGLFPEQDIGSPQRVRGAVGHGSIPNATEVTVPTARPTAGTPSSTRRSGEPQYTAGTQPPAASSTAVPSATWRQGVVWVTTQRAPWRPMKLEPSKPHTEPSTCTGASCAAGSSNTTAAGWAELRRPLRVAWAVHAYVGAALCLLLALGCIAGLGGTILQRPPRCALLLGAMGLLLAASLLRGAFLLLDPYGARGWLPPRCMLLLCSVPFTLLLGAFALLLGRLQRAAQLCLLPPSLGGLPALGVAAVLQCVAPVAADLLWPRWGLGAGLALHGVGCVFATLLLLGGLRGGWRGSRREGLRCGARALLAAGLLGVPCCALQLLSATWLRGGVGPAGRCGWPCWAAMGWMRVGEAGVGLAVLLGVAEPLWRGRREEAAGHSCWAKAVRYFCAGRKAQVPEYPNNCYEHAPTGDISKSLIRNPAEQLPLRALKDSNTALAAGTPGLSPKCPNVAVAAIRERGSSASLGELVFRPPSPIDLRRSIDQALCRRHLLREGLFGRPRRGSGASIRTFEPQTTLARCSSLTELPRGEADASVSSMESFSLKISWNPWRHGLSSPDSLPLEEAPSRAQLLAHQETPPALQPPGSEPEARRSFLALSRQVDARSLSSDTIEL", "length": 677, "header": "tr|A0A8V0ZGV2-1|A0A8V0ZGV2_CHICK Isoform 1 of Proline rich transmembrane protein 3 OS=Gallus gallus OX=9031 GN=PRRT3 PE=4 SV=1 CANONICAL=A0A8V0ZGV2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGV2/entry#A0A8V0ZGV2-1", "sequence": { 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Transcript", "id": "ENSGALT00010046709.1", "url": "https://www.ensembl.org/id/ENSGALT00010046709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027817.1", "url": "https://www.ensembl.org/id/ENSGALP00010027817.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 106, "start_aa": "Thr", "end_pos": 106, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr106", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGW5-1", "uniprot_ac": "A0A8V0ZGW5", "uniprot_id": "A0A8V0ZGW5_CHICK", "mass": { "chemical_mass": 41531.0, "monoisotopic_mass": 41531.0 }, "refseq": { "ac": "XP_015145611", "name": "transmembrane protein 198 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145611" }, "gene_names": [ { "name": "TMEM198", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW5" } ] }, { "name": "TMEM198", "type": "synonym", "evidence": [ { "id": "XP_015145611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145611" } ] } ], "protein_names": [ { "name": "Transmembrane protein 198", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW5/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 198 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015145611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145611" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145611" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM198", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW5", "locus": { "chromosome": "7", "start_pos": 21693839, "end_pos": 21698021, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021180", "url": "https://www.ensembl.org/id/ENSGALG00010021180" } ] } } ], "crossref": [ { "id": "A0A8V0ZGW5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGW5", "database": "AlphaFoldDB", "categories": [] }, { "id": "769377", "url": "https://www.ncbi.nlm.nih.gov/gene/769377", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGW5", "url": "https://www.orthodb.org/?gene=A0A8V0ZGW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31247:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31247:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145611", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLPGLPRAMTATVQTLRFKLLPHDTGQEWAHSCQQEIERRYQVVPSVVCAMCCLFGIIYCFFGYRCFKAVMFLTGLMFGSIIIFMLCYKERVLDTQLSVEASVGIGLGIGVLCGLVTMLVRSVGLFMVGLLLGLLLAVATLVVMEQFYHPPTVWIPIALLLGVGMLFAVLTLQWQRFFTTLSTAVFGSAIMTVTVDYFIELFLLVQYIYERIKVAPARPVCWYSWVILGVWPLLTVLGVLVQWKVTAEGYSHTEVIISRQQRRVQLMRIKQREDRKEKKKKRRPHHPPPHQHKAHPPEPAYRRKPNPVRRFDGDVLSPSYIQSFRERQTGPSLNSLIASSHAVVDLDYDCSSTVPLTTGSGPAMRV", "length": 367, "header": "tr|A0A8V0ZGW5-1|A0A8V0ZGW5_CHICK Isoform 1 of Transmembrane protein 198 OS=Gallus gallus OX=9031 GN=TMEM198 PE=3 SV=1 CANONICAL=A0A8V0ZGW5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW5/entry#A0A8V0ZGW5-1", "sequence": { "sequence": "MPLPGLPRAMTATVQTLRFKLLPHDTGQEWAHSCQQEIERRYQVVPSVVCAMCCLFGIIYCFFGYRCFKAVMFLTGLMFGSIIIFMLCYKERVLDTQLSVEASVGIGLGIGVLCGLVTMLVRSVGLFMVGLLLGLLLAVATLVVMEQFYHPPTVWIPIALLLGVGMLFAVLTLQWQRFFTTLSTAVFGSAIMTVTVDYFIELFLLVQYIYERIKVAPARPVCWYSWVILGVWPLLTVLGVLVQWKVTAEGYSHTEVIISRQQRRVQLMRIKQREDRKEKKKKRRPHHPPPHQHKAHPPEPAYRRKPNPVRRFDGDVLSPSYIQSFRERQTGPSLNSLIASSHAVVDLDYDCSSTVPLTTGSGPAMRV", "length": 367, "header": "tr|A0A8V0ZGW5-1|A0A8V0ZGW5_CHICK Isoform 1 of Transmembrane protein 198 OS=Gallus gallus OX=9031 GN=TMEM198 PE=3 SV=1 CANONICAL=A0A8V0ZGW5-1" }, "locus": { "chromosome": "7", "start_pos": 21696479, "end_pos": 21694988, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051328.1", "url": "https://www.ensembl.org/id/ENSGALT00010051328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030519.1", "url": "https://www.ensembl.org/id/ENSGALP00010030519.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW5" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of canonical Wnt signaling pathway", "id": "GO:0090263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGW5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGW5" }, { "id": "PF13886", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13886" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TM7S3/TM198-like", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 244, "start_aa": "Cys", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIB5-1", "uniprot_ac": "A0A8V0ZIB5", "uniprot_id": "A0A8V0ZIB5_CHICK", "mass": { "chemical_mass": 102489.0, "monoisotopic_mass": 102489.0 }, "refseq": { "ac": "XP_004949939", "name": "transcriptional protein SWT1 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949939" }, "gene_names": [ { "name": "SWT1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5" } ] }, { "name": "SWT1", "type": "synonym", "evidence": [ { "id": "XP_004949939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949939" } ] } ], "protein_names": [ { "name": "Transcriptional protein SWT1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5/entry#names_and_taxonomy" } ] }, { "name": "transcriptional protein SWT1 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_004949939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949939" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004949939.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949939" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SWT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5", "locus": { "chromosome": "8", "start_pos": 10643436, "end_pos": 10682202, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021186", "url": "https://www.ensembl.org/id/ENSGALG00010021186" } ] } } ], "crossref": [ { "id": "A0A8V0ZIB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18727", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18727", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859817", "url": "https://www.ncbi.nlm.nih.gov/gene/100859817", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGX3", "url": "https://www.orthodb.org/?gene=A0A8V0ZGX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGX6", "url": "https://www.orthodb.org/?gene=A0A8V0ZGX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGY0", "url": "https://www.orthodb.org/?gene=A0A8V0ZGY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIB5", "url": "https://www.orthodb.org/?gene=A0A8V0ZIB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIC4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16161:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16161:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949939", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKKRLKKIKEDNLNGQDDKNSEVTRSYSKSVERQTEFQRFKTRKGRQERKQHQSSNTGADGRSQGKSPNESKTTAISLIESEKRKRIVIHFKSKEVKHGKSTGAADVVTTSRGSCNKGPCDGTGRKRLCHSFAVQRDKVVKKRKVELCKLKVKAEQTVLGKRMSSVYNLYVPHKKADRSRKMSEDVRIEKKPPSTSTETVHHDRPVTKKSNTLSRTCEEKYKEGYKEFSKKNQHDNKHTSHCSTETLQQWDCSKWKKQDADQVGCNSGTEKEDFEATALCFKQGFPSPQSKAVFLLPEGCEYLEGDQEMQIVEDLHVARVEKRMAQSVVQTCGELTSMEIDLPEQDLNISAGTSPSSLNILVVIDTNIMISHLEFVKSLKSKDIPGVGKLALIIPWVVLQELDNLKKGKMLLHVRQKAIPAVQFIYMCLKNQDSKLWGQSMQLASQKIYGLSDENNDDRVLQCCLQYQSLFPQAVVILCTDDKNLCNKAIVCEVKALCKVDLVTALLNLNVNNLKNCLELQQSKCDTEFQKTKESDAHLTSPFPNIIPDLEKNLGEALSCILETEMKIAFGNLWMEILYLKPPWTLADLLQCYKKHWVAVFGYVVPRSLLATIEFLYKHFCTGKTLDTSTAVILLQETKKLLHAFSLRSDYDGVLPRAYEKVNKLYQTFTEVRSDSEQNLSEDIAVLSKSSPCERMEETTPNLQNCEEKRLPASTHDAQENRHQEIWSVLEGVWNTMNLYRLEIFQKLESNTVIAKSSFEEAFSGLQKLLAAVNYILEGICRVLAPNSSFQDIWTLYNFLISSERKIRGGLLSAGRAGPQHQAASCICTHGSKEQGVALTPARSGTTALALRFWCPNEVREVVGGNTQEAKTAFFSQWCCFIIEFKGKKKKKKLLTLTSSISCFK", "length": 906, "header": "tr|A0A8V0ZIB5-1|A0A8V0ZIB5_CHICK Isoform 1 of Transcriptional protein SWT1 OS=Gallus gallus OX=9031 GN=SWT1 PE=3 SV=1 CANONICAL=A0A8V0ZIB5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5/entry#A0A8V0ZGX3-1", "sequence": { "sequence": "MRDLLLIQNSEVTRSYSKSVERQTEFQRFKTRKGRQERKQHQSSNTGADGRSQGKSPNESKTTAISLIESEKRKRIVIHFKSKEVKHGKSTGAADVVTTSRGSCNKGPCDGTGRKRLCHSFAVQRDKVVKKRKVELCKLKVKAEQTVLGKRMSSVYNLYVPHKKADRSRKMSEDVRIEKKPPSTSTETVHHDRPVTKKSNTLSRTCEEKYKEGYKEFSKKNQHDNKHTSHCSTETLQQWDCSKWKKQDADQVGCNSGTEKEDFEATALCFKQGFPSPQSKAVFLLPEGCEYLEGDQEMQIVEDLHVARVEKRMAQSVVQTCGELTSMEIDLPEQDLNISAGTSPSSLNILVVIDTNIMISHLEFVKSLKSKDIPGVGKLALIIPWVVLQELDNLKKGKMLLHVRQKAIPAVQFIYMCLKNQDSKLWGQSMQLASQKIYGLSDENNDDRVLQCCLQYQSLFPQAVVILCTDDKNLCNKAIVCEVKALCKVDLVTALLNLNVNNLKNCLELQQSKCDTEFQKTKESDAHLTSPFPNIIPDLEKNLGEALSCILETEMKIAFGNLWMEILYLKPPWTLADLLQCYKKHWVAVFGYVVPRSLLATIEFLYKHFCTGKTLDTSTAVILLQETKKLLHAFSLRSDYDGVLPRAYEKVNKLYQTFTEVRSDSEQNLSEDIAVLSKSSPCERMEETTPNLQNCEEKRLPASTHDAQENRHQEIWSVLEGVWNTMNLYRLEIFQKLESNTVIAKSSFEEAFSGLQKLLAAVNYILEGICRVLAPNSSFQDIWTLYNFLISSEINNSIKFTAEELYECVSQELYRGRLEVGCCQLAELDHSIKQRHASVHMEAKNRGWL", "length": 849, "header": "tr|A0A8V0ZGX3-1|A0A8V0ZIB5_CHICK Computationally mapped isoform of Transcriptional protein SWT1 OS=Gallus gallus OX=9031 GN=SWT1 PE=3 SV=1 CANONICAL=A0A8V0ZIB5-1" }, "locus": { "chromosome": "8", "start_pos": 10679674, "end_pos": 10645123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051338.1", "url": "https://www.ensembl.org/id/ENSGALT00010051338.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030529.1", "url": "https://www.ensembl.org/id/ENSGALP00010030529.1" } ] } }, { "isoform_ac": "A0A8V0ZGX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5/entry#A0A8V0ZGX6-1", "sequence": { "sequence": "MKCSSPRAAGGLIVHIAASSSQNSEVTRSYSKSVERQTEFQRFKTRKGRQERKQHQSSNTGADGRSQGKSPNESKTTAISLIESEKRKRIVIHFKSKEVKHGKSTGAADVVTTSRGSCNKGPCDGTGRKRLCHSFAVQRDKVVKKRKVELCKLKVKAEQTVLGKRMSSVYNLYVPHKKADRSRKMSEDVRIEKKPPSTSTETVHHDRPVTKKSNTLSRTCEEKYKEGYKEFSKKNQHDNKHTSHCSTETLQQWDCSKWKKQDADQVGCNSGTEKEDFEATALCFKQGFPSPQSKAVFLLPEGCEYLEGDQEMQIVEDLHVARVEKRMAQSVVQTCGELTSMEIDLPEQDLNISAGTSPSSLNILVVIDTNIMISHLEFVKSLKSKDIPGVGKLALIIPWVVLQELDNLKKGKMLLHVRQKAIPAVQFIYMCLKNQDSKLWGQSMQLASQKIYGLSDENNDDRVLQCCLQYQSLFPQAVVILCTDDKNLCNKAIVCEVKALCKVDLVTALLNLNVNNLKNCLELQQSKCDTEFQKTKESDAHLTSPFPNIIPDLEKNLGEALSCILETEMKIAFGNLWMEILYLKPPWTLADLLQCYKKHWVAVFGYVVPRSLLATIEFLYKHFCTGKTLDTSTAVILLQETKKLLHAFSLRSDYDGVLPRAYEKVNKLYQTFTEVRSDSEQNLSEDIAVLSKSSPCERMEETTPNLQNCEEKRLPASTHDAQENRHQEIWSVLEGVWNTMNLYRLEIFQKLESNTVIAKSSFEEAFSGLQKLLAAVNYILEGICRVLAPNSSFQDIWTLYNFLISSEINNSIKFTAEELYECVSQELYRGRLEVGCCQLAELDHSIKQRHASVHMEAKNRGWL", "length": 863, "header": "tr|A0A8V0ZGX6-1|A0A8V0ZGX6_CHICK Computationally mapped isoform of Transcriptional protein SWT1 OS=Gallus gallus OX=9031 GN=SWT1 PE=3 SV=1 CANONICAL=A0A8V0ZIB5-1" }, "locus": { "chromosome": "8", "start_pos": 10680733, "end_pos": 10645123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051343.1", "url": "https://www.ensembl.org/id/ENSGALT00010051343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030534.1", "url": "https://www.ensembl.org/id/ENSGALP00010030534.1" } ] } }, { "isoform_ac": "A0A8V0ZGY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5/entry#A0A8V0ZGY0-1", "sequence": { "sequence": "MSKKRLKKIKEDNLNGQDDKNSEVTRSYSKSVERQTEFQRFKTRKGRQERKQHQSSNTGADGRSQGKSPNESKTTAISLIESEKRKRIVIHFKSKEVKHGKSTGAADVVTTSRGSCNKGPCDGTGRKRLCHSFAVQRDKVVKKRKVELCKLKVKAEQTVLGKRMSSVYNLYVPHKKADRSRKMSEDVRIEKKPPSTSTETVHHDRPVTKKSNTLSRTCEEKYKEGYKEFSKKNQHDNKHTSHCSTETLQQWDCSKWKKQDADQVGCNSGTEKEDFEATALCFKQGFPSPQSKAVFLLPEGCEYLEGDQEVRVGKLALIIPWVVLQELDNLKKGKMLLHVRQKAIPAVQFIYMCLKNQDSKLWGQSMQLASQKIYGLSDENNDDRVLQCCLQYQSLFPQAVVILCTDDKNLCNKAIVCEVKALCKVDLVTALLNLNVNNLKNCLELQQSKCDLEKNLGEALSCILETEMKIAFGNLWMEILYLKPPWTLADLLQCYKKHWVAVFGYVVPRSLLATIEFLYKHFCTGKTLDTSTAVILLQETKKLLHAFSLRSDYDGVLPRAYEKVNKLYQTFTEVRSDSEQNLSEDIAVLSKSSPCERMEETTPNLQNCEEKRLPASTHDAQENRHQEIWSVLEGVWNTMNLYRLEIFQKLESNTVIAKSSFEEAFSGLQKLLAAVNYILEGICRVLAPNSSFQDIWTLYNFLISSEINNSIKFTAEELYECVSQELYRGRLEVGCCQLAELDHSIKQRHASVHMEAKNRGWL", "length": 762, "header": "tr|A0A8V0ZGY0-1|A0A8V0ZGY0_CHICK Computationally mapped isoform of Transcriptional protein SWT1 OS=Gallus gallus OX=9031 GN=SWT1 PE=3 SV=1 CANONICAL=A0A8V0ZIB5-1" }, "locus": { "chromosome": "8", "start_pos": 10680881, "end_pos": 10645123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051348.1", "url": "https://www.ensembl.org/id/ENSGALT00010051348.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030539.1", "url": "https://www.ensembl.org/id/ENSGALP00010030539.1" } ] } }, { "isoform_ac": "A0A8V0ZIB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5/entry#A0A8V0ZIB5-1", "sequence": { "sequence": "MSKKRLKKIKEDNLNGQDDKNSEVTRSYSKSVERQTEFQRFKTRKGRQERKQHQSSNTGADGRSQGKSPNESKTTAISLIESEKRKRIVIHFKSKEVKHGKSTGAADVVTTSRGSCNKGPCDGTGRKRLCHSFAVQRDKVVKKRKVELCKLKVKAEQTVLGKRMSSVYNLYVPHKKADRSRKMSEDVRIEKKPPSTSTETVHHDRPVTKKSNTLSRTCEEKYKEGYKEFSKKNQHDNKHTSHCSTETLQQWDCSKWKKQDADQVGCNSGTEKEDFEATALCFKQGFPSPQSKAVFLLPEGCEYLEGDQEMQIVEDLHVARVEKRMAQSVVQTCGELTSMEIDLPEQDLNISAGTSPSSLNILVVIDTNIMISHLEFVKSLKSKDIPGVGKLALIIPWVVLQELDNLKKGKMLLHVRQKAIPAVQFIYMCLKNQDSKLWGQSMQLASQKIYGLSDENNDDRVLQCCLQYQSLFPQAVVILCTDDKNLCNKAIVCEVKALCKVDLVTALLNLNVNNLKNCLELQQSKCDTEFQKTKESDAHLTSPFPNIIPDLEKNLGEALSCILETEMKIAFGNLWMEILYLKPPWTLADLLQCYKKHWVAVFGYVVPRSLLATIEFLYKHFCTGKTLDTSTAVILLQETKKLLHAFSLRSDYDGVLPRAYEKVNKLYQTFTEVRSDSEQNLSEDIAVLSKSSPCERMEETTPNLQNCEEKRLPASTHDAQENRHQEIWSVLEGVWNTMNLYRLEIFQKLESNTVIAKSSFEEAFSGLQKLLAAVNYILEGICRVLAPNSSFQDIWTLYNFLISSERKIRGGLLSAGRAGPQHQAASCICTHGSKEQGVALTPARSGTTALALRFWCPNEVREVVGGNTQEAKTAFFSQWCCFIIEFKGKKKKKKLLTLTSSISCFK", "length": 906, "header": "tr|A0A8V0ZIB5-1|A0A8V0ZIB5_CHICK Isoform 1 of Transcriptional protein SWT1 OS=Gallus gallus OX=9031 GN=SWT1 PE=3 SV=1 CANONICAL=A0A8V0ZIB5-1" }, "locus": { "chromosome": "8", "start_pos": 10680881, "end_pos": 10644923, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051340.1", "url": "https://www.ensembl.org/id/ENSGALT00010051340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030531.1", "url": "https://www.ensembl.org/id/ENSGALP00010030531.1" } ] } }, { "isoform_ac": "A0A8V0ZIC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5/entry#A0A8V0ZIC4-1", "sequence": { "sequence": "MGGKMSKKRLKKIKEDNLNGQDDKNSEVTRSYSKSVERQTEFQRFKTRKGRQERKQHQSSNTGADGRSQGKSPNESKTTAISLIESEKRKRIVIHFKSKEVKHGKSTGAADVVTTSRGSCNKGPCDGTGRKRLCHSFAVQRDKVVKKRKVELCKLKVKAEQTVLGKRMSSVYNLYVPHKKADRSRKMSEDVRIEKKPPSTSTETVHHDRPVTKKSNTLSRTCEEKYKEGYKEFSKKNQHDNKHTSHCSTETLQQWDCSKWKKQDADQVGCNSGTEKEDFEATALCFKQGFPSPQSKAVFLLPEGCEYLEGDQEMQIVEDLHVARVEKRMAQSVVQTCGELTSMEIDLPEQDLNISAGTSPSSLNILVVIDTNIMISHLEFVKSLKSKDIPGVGKLALIIPWVVLQELDNLKKGKMLLHVRQKAIPAVQFIYMCLKNQDSKLWGQSMQLASQKIYGLSDENNDDRVLQCCLQYQSLFPQAVVILCTDDKNLCNKAIVCEVKALCKVDLVTALLNLNVNNLKNCLELQQSKCDTEFQKTKESDAHLTSPFPNIIPDLEKNLGEALSCILETEMKIAFGNLWMEILYLKPPWTLADLLQCYKKHWVAVFGYVVPRSLLATIEFLYKHFCTGKTLDTSTAVILLQETKKLLHAFSLRSDYDGVLPRAYEKVNKLYQTFTEVRSDSEQNLSEDIAVLSKSSPCERMEETTPNLQNCEEKRLPASTHDAQENRHQEIWSVLEGVWNTMNLYRLEIFQKLESNTVIAKSSFEEAFSGLQKLLAAVNYILEGICRVLAPNSSFQDIWTLYNFLISSEINNSIKFTAEELYECVSQELYRGRLEVGCCQLAELDHSIKQRHASVHMEAKNRGWL", "length": 865, "header": "tr|A0A8V0ZIC4-1|A0A8V0ZIC4_CHICK Computationally mapped isoform of Transcriptional protein SWT1 OS=Gallus gallus OX=9031 GN=SWT1 PE=3 SV=1 CANONICAL=A0A8V0ZIB5-1" }, "locus": { "chromosome": "8", "start_pos": 10681921, "end_pos": 10645123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051350.1", "url": "https://www.ensembl.org/id/ENSGALT00010051350.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030541.1", "url": "https://www.ensembl.org/id/ENSGALP00010030541.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 788, "end_pos": 790, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIB5" }, { "id": "SM00670", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00670" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIN", "eco_id": "ECO_0000259", "start_pos": 361, "end_pos": 488, "start_aa": "Ile", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 349, "end_pos": 351 }, { "start_pos": 680, "end_pos": 682 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 788, "end_pos": 790 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZGY1-1", "uniprot_ac": "A0A8V0ZGY1", "uniprot_id": "A0A8V0ZGY1_CHICK", "mass": { "chemical_mass": 87738.0, "monoisotopic_mass": 87738.0 }, "refseq": { "ac": "NP_001186615", "name": "zinc finger FYVE domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186615" }, "gene_names": [ { "name": "ZFYVE1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ] }, { "name": "ZFYVE1", "type": "synonym", "evidence": [ { "id": "NP_001186615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186615" } ] } ], "protein_names": [ { "name": "Zinc finger FYVE domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1/entry#names_and_taxonomy" } ] }, { "name": "zinc finger FYVE domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001186615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186615" } ] }, { "name": "zinc finger, FYVE domain containing 1", "type": "synonym", "evidence": [ { "id": "NP_001186615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186615" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.163515.1, SRR13267652.24863.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Dec 14, 2021 this sequence version replaced NP_001186615.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186615", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186615" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZFYVE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1", "locus": { "chromosome": "5", "start_pos": 25973119, "end_pos": 25950120, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021022", "url": "https://www.ensembl.org/id/ENSGALG00010021022" } ] } } ], "crossref": [ { "id": "A0A8V0ZGY1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZGY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01851", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01851", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15734", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15734", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19819", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19819", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19820", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19820", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423252", "url": "https://www.ncbi.nlm.nih.gov/gene/423252", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423252", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423252", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYWIPDS", "url": "https://omabrowser.org/oma/group/SYWIPDS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGY1", "url": "https://www.orthodb.org/?gene=A0A8V0ZGY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46624", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46624", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46624:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46624:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22586", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22586", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186615", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186615", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAHTQTAEKGQNTALLCQESYVCSGTDEAVFECDECWSLQCQRCEEELHQPERLRNHERTRIRPGHVPYCDSCKGANGNIMHASMTGSRQIAAVRCQVCKINLCVECQKRTHAGGNRRKHPVTVYHAGKAQEQEEEEMDEETRRRKMAEKVVSFLLVDETEEIQVRNEEDFIKKLDCSPDQHLKVVSIFGNTGDGKSHTLNHAFFYGREVFKTSPAQESCTVGVWAAYDPVRKVVVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTRADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPGVIIFHETVYTKLLGSDHPSEVPEKLIQDRFRKLSCFPEAFSSIHYKGTRTYNPPTDFSGLRRAVEQQLENNTTRSPRQPGVIYKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSVCLSCGCGCKKSMNHTKEGVPHESKSRCRYSHQYDNRVYTCKACYERGMEVSVVPKTSASTDSPWLGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVNTVVRTEIEHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNKCNTPFKDNDTKHHCRACGEGFCDGCSSKTRPVPERGWGPAPVRVCDNCYENRGIQLDVAELPSDEEGGTLIARKVGEAVQNTLGAVVTAMDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL", "length": 781, "header": "tr|A0A8V0ZGY1-1|A0A8V0ZGY1_CHICK Isoform 1 of Zinc finger FYVE domain-containing protein 1 OS=Gallus gallus OX=9031 GN=ZFYVE1 PE=1 SV=1 CANONICAL=A0A8V0ZGY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1/entry#A0A8V0ZGY1-1", "sequence": { "sequence": "MSAHTQTAEKGQNTALLCQESYVCSGTDEAVFECDECWSLQCQRCEEELHQPERLRNHERTRIRPGHVPYCDSCKGANGNIMHASMTGSRQIAAVRCQVCKINLCVECQKRTHAGGNRRKHPVTVYHAGKAQEQEEEEMDEETRRRKMAEKVVSFLLVDETEEIQVRNEEDFIKKLDCSPDQHLKVVSIFGNTGDGKSHTLNHAFFYGREVFKTSPAQESCTVGVWAAYDPVRKVVVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTRADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPGVIIFHETVYTKLLGSDHPSEVPEKLIQDRFRKLSCFPEAFSSIHYKGTRTYNPPTDFSGLRRAVEQQLENNTTRSPRQPGVIYKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSVCLSCGCGCKKSMNHTKEGVPHESKSRCRYSHQYDNRVYTCKACYERGMEVSVVPKTSASTDSPWLGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVNTVVRTEIEHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNKCNTPFKDNDTKHHCRACGEGFCDGCSSKTRPVPERGWGPAPVRVCDNCYENRGIQLDVAELPSDEEGGTLIARKVGEAVQNTLGAVVTAMDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL", "length": 781, "header": "tr|A0A8V0ZGY1-1|A0A8V0ZGY1_CHICK Isoform 1 of Zinc finger FYVE domain-containing protein 1 OS=Gallus gallus OX=9031 GN=ZFYVE1 PE=1 SV=1 CANONICAL=A0A8V0ZGY1-1" }, "locus": { "chromosome": "5", "start_pos": 25971029, "end_pos": 25951045, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050854.1", "url": "https://www.ensembl.org/id/ENSGALT00010050854.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030045.1", "url": "https://www.ensembl.org/id/ENSGALP00010030045.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423252", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423252", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TTG3-1", "protein_name": "Zinc finger FYVE domain-containing protein 1", "gene_name": "ZFYVE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVGDFLTKLSMSAQTSPAEKGLNPGLLCQESYTCSGTDEAVFECDECCSLQCLRCEEELHRQERLRNHERIRLKAGHVPYCDPCKGPNGHSPGMKQRAVVRCQTCKINLCLECQKRTHSGGSKRRHPVTVYHVAKVQELLEDEGMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPAQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQQLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGAGCKNSMNHGKEGVPHEAKSRCRYSHQYDNRVFTCKACYERGNEVSVVPKTAASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQADDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSVKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL", "length": 787 }, "evidence": [ { "id": "A0A8V0ZGY1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGY1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A3T4-1", "protein_name": "Zinc finger FYVE domain-containing protein 1", "gene_name": "Zfyve1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAQTSLAEKGLNPGLMCQESYACSGTDEAVFECDECCSLQCLRCEEELHRQERLRNHERIRLKAGHVPYCDPCKGPNGHSPGVRQRAAVRCQTCKINLCLECQKRTHSGGNKRRHPVTVYHVSKVQESLEGEEMDEETKRRKMTERVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFHGREVFKTSPAQESCTVGVWAAHDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEAPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGAGCKNSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGKEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDAFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNQCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYDARNVQLDVAEAQADDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSVKLSKHHCRACGQGFCDECSHGRRAVPSRGWDHPVRVCFNCNKKPGDL", "length": 777 }, "evidence": [ { "id": "A0A8V0ZGY1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGY1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BPK7-1", "protein_name": "Zinc finger FYVE domain-containing protein 1", "gene_name": "ZFYVE1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAQTSPAEKGLNPGLLCQESYTCSGTDEAVFECDECCSLQCLRCEEELHRQERLRNHERIRLKAGHVPYCDPCKGPSGHSPGVKQRAVVRCQTCKINLCLECQKRTHSGGNKRRHPITVYHVTKVQELLEEEGMDEETKRKKMTEKVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPAQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEVPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQQLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGAGCKNSMNHGKEGVPHEAKSRCRYSHQYDNRVFTCKACYERGNEVSVVPKTAASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDGFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNSQLDVTEAQGDDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHSCRKEFSVKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVRVCFNCNKKPGDL", "length": 777 }, "evidence": [ { "id": "A0A8V0ZGY1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGY1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q810J8-1", "protein_name": "Zinc finger FYVE domain-containing protein 1", "gene_name": "Zfyve1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAQTSLAEKGLNPGLMCQESYACSGTDEAIFECDECCSLQCLRCEEELHRQERLRNHERIRLKAGHVPYCDPCKGPNGHSPGVRQRAAVRCQTCKINLCLECQKRTHSGGNKRRHPITVYLVSKVQESLEGEEMDEETKRKKMTERVVSFLLVDENEEIQVTNEEDFIRKLDCKPDQHLKVVSIFGNTGDGKSHTLNHTFFYGREVFKTSPAQESCTVGVWAAYDPVHKVAVIDTEGLLGATVNLSQRTRLLLKVLAISDLVIYRTHADRLHNDLFKFLGDASEAYLKHFTKELKATTARCGLDVPLSTLGPAVIIFHETVHTQLLGSDHPSEAPEKLIQDRFRKLGRFPEAFSSIHYKGTRTYNPPTDFSGLRRALEQLLENNTTRSPRHPGVIFKALKALSDRFSGEIPDDQMAHSSFFPDEYFTCSSLCLSCGAGCKNSMNHGKEGVPHEAKSRCRYSHQYDNRVYTCKACYERGKEVSVVPKTSASTDSPWMGLAKYAWSGYVIECPNCGVVYRSRQYWFGNQDPVDTVVRTEIVHVWPGTDAFLKDNNNAAQRLLDGMNFMAQSVSELSLGPTKAVTSWLTDQIAPAYWRPNSQILSCNQCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDSCYDARNVQLDVTEAQADDEGGTLIARKVGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSVKLSKHHCRACGQGFCDECSHDCRAVPSRGWDHPVRVCFNCNKKPGDL", "length": 777 }, "evidence": [ { "id": "A0A8V0ZGY1", "url": "https://omabrowser.org/oma/group/A0A8V0ZGY1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "host-mediated activation of viral genome replication", "id": "GO:0044829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "macroautophagy", "id": "GO:0016236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016236", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "lipid droplet formation", "id": "GO:0140042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4-bisphosphate binding", "id": "GO:0043325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "1-phosphatidylinositol binding", "id": "GO:0005545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005545", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 9, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "mitochondria-associated endoplasmic reticulum membrane contact site", "id": "GO:0044233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" }, { "name": "extrinsic component of omegasome membrane", "id": "GO:0097629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 618, "end_pos": 620, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY1" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 602, "end_pos": 663, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 249, "end_pos": 251 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 618, "end_pos": 620 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"length": 1194, "header": "tr|A0A8V0ZGY3-1|A0A8V0ZGY3_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=HIPK3 PE=3 SV=1 CANONICAL=A0A8V0ZGY3-1" }, "locus": { "chromosome": "5", "start_pos": 6623367, "end_pos": 6552605, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046770.1", "url": "https://www.ensembl.org/id/ENSGALT00010046770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027847.1", "url": "https://www.ensembl.org/id/ENSGALP00010027847.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ], "pmid": "" }, { "name": "protein tyrosine kinase activity", "id": "GO:0004713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ], "pmid": "" }, { "name": "mRNA transcription", "id": "GO:0009299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009299", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZGY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1033, "end_pos": 1035, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1132, "end_pos": 1134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 677, "end_pos": 679, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": 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"A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZH18-1", "uniprot_ac": "A0A8V0ZH18", "uniprot_id": "A0A8V0ZH18_CHICK", "mass": { "chemical_mass": 68760.0, "monoisotopic_mass": 68760.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC33", "type": "recommended", "evidence": [ { "id": "A0A8V0ZH18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH18" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 33", "type": "synonym", "evidence": [ { "id": "A0A8V0ZH18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH18/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH18" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH18", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZH18", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZH18", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR039889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH18", "url": "https://www.orthodb.org/?gene=A0A8V0ZH18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIG1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21623", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21623", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { 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"https://www.ensembl.org/id/ENSGALT00010051388.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030579.1", "url": "https://www.ensembl.org/id/ENSGALP00010030579.1" } ] } }, { "isoform_ac": "A0A8V0ZIG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH18/entry#A0A8V0ZIG1-1", "sequence": { "sequence": "MAGESRVPASLQRWRLRAEDKVLDFEFEVLSAQFNRRGRYALRLSVENPLLRDSGDSVRLRTGDGDSVPTSTGTTDTVLQGHLGEICAFRRKKFTFTLPRGYCKNDKNHDVRLRIEALHCPGTPLRRKRVGEAFFAIYPRPDQPRVKLLAGRDEDWYRYSAVLALLRAGSEQPAMHCGRLAFTAALHEHRPPAVVSPAPSPHAQDRGHRAASTAPSPASPAGPSPSVPLHSPESAYHSLPTEVPQADPVLSSSLELRGDSTGEQPSSSSSSSSSGPPLSFHLSSPESSLDPSPWAVQEVSRYRLALRRMAGDLVSLHQRVTSLEVENGHLRHSLAGRQEPGRALLTDGDVDVMTREEVLDRLATLKEELVSSTAEMRQLRDRVQRLQNELIRKNDQEKELVLLQRAHRQQQGALRRCREEVARTKGLEEMVRQQEKVIRVMERMLQEKLSRSAEKPAGEAPAGELHALLLAENRRLREELARPPSPPLPPSTPRPPQNTFGGTEKLSLLAKLEEAQTRGRAMERQLEEAARRWAREKQELGTRLLEKDHGFGGSAPRLLHATTLKRPPDLTLPPRRPRTLDPLP", "length": 584, "header": "tr|A0A8V0ZIG1-1|A0A8V0ZIG1_CHICK Computationally mapped isoform of Coiled-coil domain containing 33 OS=Gallus gallus OX=9031 GN=CCDC33 PE=4 SV=1 CANONICAL=A0A8V0ZH18-1" }, "locus": { "chromosome": "10", "start_pos": 2611991, "end_pos": 2590573, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051389.1", "url": "https://www.ensembl.org/id/ENSGALT00010051389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030580.1", "url": "https://www.ensembl.org/id/ENSGALP00010030580.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZH19-1", "uniprot_ac": "A0A8V0ZH19", "uniprot_id": "A0A8V0ZH19_CHICK", "mass": { "chemical_mass": 44273.0, "monoisotopic_mass": 44273.0 }, "refseq": {}, "gene_names": [ { "name": "MAJIN", "type": "recommended", "evidence": [ { "id": "A0A8V0ZH19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH19" } ] } ], "protein_names": [ { "name": "Membrane anchored junction protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZH19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH19/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAJIN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH19", "locus": { "chromosome": "15", "start_pos": 9914771, "end_pos": 9921731, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021037", "url": "https://www.ensembl.org/id/ENSGALG00010021037" } ] } } ], "crossref": [ { "id": "A0A8V0ZH19", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZH19", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR027816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH19", "url": "https://www.orthodb.org/?gene=A0A8V0ZH19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35824:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35824:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15077", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15077", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZH19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWKAPGVVFLSQDPDDSNTGLVQSWGGPPSQTATCAAQDVSWGHWRGDQAVFCGRQEEQEVLPCAPHSCGLPAVPAGLQAAAYTRHRSCSRCVGLIGAAAQGCAGLCAVRGARWGARDSLLPSEVIKEMPLKPFTYPLPETRFLHAGGVVYKFKIRYGNLQSAPELNNTDIAVKEFEEAIRVILGNLDDLHPFSTDHFTIFPYLSKWERVSKMRFKHKNVNLVPYPYICTMYLELNSFQQSLSLGREVNSDTSEPVKRKSEIPEMTDMEETVKRRRVEGQTETSYPKLCMDRPGAESVHCVIKAEHGLEKNYSKEIQREHSPASLSMGCNQESLWGPVGYNVEGRAETTQAEGEMQVLQQMDQISTKGTVEPKRGRLSKFWRRVFSPLQHLFGGKH", "length": 396, "header": "tr|A0A8V0ZH19-1|A0A8V0ZH19_CHICK Isoform 1 of Membrane anchored junction protein OS=Gallus gallus OX=9031 GN=MAJIN PE=4 SV=1 CANONICAL=A0A8V0ZH19-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZH19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH19/entry#A0A8V0ZH19-1", "sequence": { "sequence": "MWKAPGVVFLSQDPDDSNTGLVQSWGGPPSQTATCAAQDVSWGHWRGDQAVFCGRQEEQEVLPCAPHSCGLPAVPAGLQAAAYTRHRSCSRCVGLIGAAAQGCAGLCAVRGARWGARDSLLPSEVIKEMPLKPFTYPLPETRFLHAGGVVYKFKIRYGNLQSAPELNNTDIAVKEFEEAIRVILGNLDDLHPFSTDHFTIFPYLSKWERVSKMRFKHKNVNLVPYPYICTMYLELNSFQQSLSLGREVNSDTSEPVKRKSEIPEMTDMEETVKRRRVEGQTETSYPKLCMDRPGAESVHCVIKAEHGLEKNYSKEIQREHSPASLSMGCNQESLWGPVGYNVEGRAETTQAEGEMQVLQQMDQISTKGTVEPKRGRLSKFWRRVFSPLQHLFGGKH", "length": 396, "header": "tr|A0A8V0ZH19-1|A0A8V0ZH19_CHICK Isoform 1 of Membrane anchored junction protein OS=Gallus gallus OX=9031 GN=MAJIN PE=4 SV=1 CANONICAL=A0A8V0ZH19-1" }, "locus": { "chromosome": "15", "start_pos": 9921405, "end_pos": 9915090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050901.1", "url": "https://www.ensembl.org/id/ENSGALT00010050901.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030092.1", "url": "https://www.ensembl.org/id/ENSGALP00010030092.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "meiotic attachment of telomere to nuclear envelope", "id": "GO:0070197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH19" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH19" } ], "pmid": "" } ] }, { 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"uniprot_ac": "A0A8V0ZH35", "uniprot_id": "A0A8V0ZH35_CHICK", "mass": { "chemical_mass": 94798.0, "monoisotopic_mass": 94798.0 }, "refseq": {}, "gene_names": [ { "name": "IRAG1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZH35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH35" } ] } ], "protein_names": [ { "name": "Inositol 1,4,5-triphosphate receptor associated 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZH35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH35/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IRAG1", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF05781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-418457", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418457", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZH35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTLPEENEQPKEAQCNSSTPAKDTGSEGTTSSTPSIVLPENAGMPDVEIDKNLVNRPRSPHRRHSNRATRNSTSSLTSVDNNGHVIDLVNDQLPDVNISEEDKKKNLELLEEAKKVSERFLMRRGRKSRSSLPESPTAVSPTLSPKVSPVTSRSNSLTLPIPSGSDVCTATSVESVSPVQNNRTFKEDDRQAAENVSKGLMDRRLNDQRKISQGRLVPRSAGFENSKEKLSEQKENFDPCKHVDTLPKCSPSGSDGGRMSLNTCLNVCENEFGKSFLKKAKENDVPLRTCLPGPGIGNIDSKLKSPIPEMRDHKVSFKPEFKLCGLRPPLLRAVSWDSLEPGQKDKTPVKLPSEEDKSFVVGNKSSNQIKAFKDLQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPELSEAAEQEKGPSPLPSPTEEEETKNSSDVMPGIPDILLRKLRVHKSLPGSSPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENAEKELENFKTAITSSAHLWHHYEHREAYQKLLEDIAVLRRLAARLSSRAEMVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRNYGASAEDGVPRSSRSMSLTVGKNMPRRRVSVAVVPKFNSLNIPGQSPTASPIPSMPSLSESPSNGKSNLTSNPVLPAVLENGKTNGEPDCETSTSTVTQGGLEEINPETKAKIEEEAYNKGYQEGLKKTKELQDLKEEDEETPKEGLHDEHEESENDSEIKNLKSRLEVVINYLYILYPKLCKHWNVVWLIVAAIIIFAVLLGIYHSYSSCDEVSERPEGKASCSAAHQYSWWNSGFQHEQRTE", "length": 848, "header": "tr|A0A8V0ZH35-1|A0A8V0ZH35_CHICK Isoform 1 of Inositol 1,4,5-triphosphate receptor associated 1 OS=Gallus gallus OX=9031 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"MPTLPEENEQPKEAQCNSSTPAKDTGSEGTTSSTPSIVLPENAGMPDVEIDKNLVNRPRSPHRRHSNRATRNSTSSLTSVDNNGHVIDLVNDQLPDVNISEEDKKKNLELLEEAKKVSERFLMRRGRKSRSSLPESPTAVSPTLSPKVSPVTSRSNSLTLPIPSGSDVCTATSVESVSPVQNNRTFKEDDRQAAENVSKGLMDRRLNDQRKISQGRLVPRSAGFENSKEKLSEQKENFDPCKHVDTLPKCSPSGSDGGRMSLNTCLNVCENEFGKSFLKKAKENDVPLRTCLPGPGIGNIDSKLKSPIPEMRDHKVSFKPEFKLCGLRPPLLRAVSWDSLEPGQKDKTPVKLPSEEDKSFVVGNKSSNQIKAFKDLQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPELSEAAEQEKGPSPLPSPTEEEETKNSSDVMPGIPDILLRKLRVHKSLPGSSPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENAEKELENFKTAITSSAHLWHHYEHREAYQKLLEDIAVLRRLAARLSSRAEMVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRNYGASAEDGVPRSSRSMSLTVGKNMPRRRVSVAVVPKFNSLNIPGQSPTASPIPSMPSLSESPSNGKSNLTSNPVLPAVLENGKTNGEPDCETSTSTVTQGGLEEINPETKAKIEEEAYNKGYQEGLKKTKELQDLKEEDEETPKEGLHDEHEESENDSEIKNLKSRLEVVINYLYILYPKLCKHWNVVWLIVAAIIIFAVLLGIYHSYSSCDEVSERPEGKASCSAAHQYSWWNSGFQHEQRTE", "length": 848, "header": "tr|A0A8V0ZH35-1|A0A8V0ZH35_CHICK Isoform 1 of Inositol 1,4,5-triphosphate receptor associated 1 OS=Gallus gallus OX=9031 GN=IRAG1 PE=1 SV=1 CANONICAL=A0A8V0ZH35-1" }, "locus": { "chromosome": "5", "start_pos": 8558274, "end_pos": 8526596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050943.1", "url": "https://www.ensembl.org/id/ENSGALT00010050943.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030134.1", "url": "https://www.ensembl.org/id/ENSGALP00010030134.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ 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"site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZH41-1", "uniprot_ac": "A0A8V0ZH41", "uniprot_id": "A0A8V0ZH41_CHICK", "mass": { "chemical_mass": 115512.0, "monoisotopic_mass": 115512.0 }, "refseq": { "ac": "XP_421618", "name": "synaptopodin 2-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421618" }, "gene_names": [ { "name": "SYNPO2L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZH41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41" } ] }, { "name": "SYNPO2L", "type": "synonym", "evidence": [ { "id": "XP_421618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421618" } ] } ], "protein_names": [ { "name": "Synaptopodin 2-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZH41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41/entry#names_and_taxonomy" } ] }, { "name": "synaptopodin 2-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_421618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421618" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_421618.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421618" } ] }, { "annotation": "Actin-associated protein that may play a role in modulating actin-based shape.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41#function" }, { "database": "UniProtKB", "id": "ARBA00057136", "url": "https://www.uniprot.org/uniprotkb/ARBA00057136#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYNPO2L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41", "locus": { "chromosome": "6", "start_pos": 16781307, "end_pos": 16749859, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021220", "url": "https://www.ensembl.org/id/ENSGALG00010021220" } ] } } ], "crossref": [ { "id": "A0A8V0ZH41", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZH41", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10820", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10820", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423743", "url": "https://www.ncbi.nlm.nih.gov/gene/423743", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PGPYQGV", "url": "https://omabrowser.org/oma/group/PGPYQGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH41", "url": "https://www.orthodb.org/?gene=A0A8V0ZH41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24217", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24217", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24217:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24217:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421618", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAEEEMLITLSGGAPWGFRLQGGSEQKRPLQVSKIRKRSKACRGGLWENDVLVSINGKSCAGLSHASAMQIIDSSNGMLNIRVKRTVGGDQTGPRLQRSPSPGQRVLSPPSPLSPTAQLLSSGPAGAPATTQSSQPRRPQRHLESLTSPPDSEAYYGETDSDADNVAQEKHRRARKKSPRSPPDSTNSKADVPQDEVSLSEQSGYESLPEAAVQEEAKDASCSGVAKREIACPPGSCADTPFSESEGQLRSSSTEGREPSPETMLLPHATKAIRAERHLIPMVGPVEHPVDEDLTTTYMEKAKQAKLHRHESIQEKNVKEAKTKCKTIASLLTDAPNPHSKGVLMFKKRRQRAKKYTLVSFGSVDEDRSYEEEDGIFPTSESEFDEEGFSDARSLTNHSDWDNTYLDIEKGKSDSEQKEEKQKGLSEASGKGARLFEQQRERAGKYTVEKVPAQRSPQLTPAAQPQPGMVNGDMPVPQKTASVPLSIHLEGVPSKMPATTPTQVLAPPSPTVFPHPPGTPDPFSSSTSMFNRSARPFTPGFSGQRPATSSVIFRPSVPKKPSESLGGQSTVVSPFSPLAPGTPTSAPAPTHRGPVSSSTSLYIPAPGRPTTPLESQPRAGGSGPETKPSASPARTSTASIFLSTPSKPGGEAASAASQPRVPGTASSSLYISPAPAQHMVSTSPLPVQLSANSAATPRPPSEPLTSREQRIAVPAPRTGILQEARRRGNKKPMFSKVEEKKNSPNPELLSLVQNLDEKPKGDHPGAGFESGPEEDFLSLGAEACNFMQSSGRKFKTPPPVAPKPQQQDGGLVNGAHDMPQLKGKGAQLFAKRQSRMDKFVVETATKPESKPRTPSPSPSLPSSWKYSPNIRAPPPIAYNPMHSPFYPLAASKSQASKAESKVKKAPGQKSGNKAIDVMHHQPYQLKSAMFCFGDPPSSSTQESPGQPGQQASSSFTAAKQIPVKTAKTQEIRRFSTPAPMPASSSLAPTVLVPRSATTLDEPVWRTEMASSAPATPAPFQMELSQSPKPYQSSPEFGQASLGPSPNPASASRFQVARPKFSAARTGMQANVWRPSFGHH", "length": 1080, "header": "tr|A0A8V0ZH41-1|A0A8V0ZH41_CHICK Isoform 1 of Synaptopodin 2-like protein OS=Gallus gallus OX=9031 GN=SYNPO2L PE=3 SV=1 CANONICAL=A0A8V0ZH41-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZH41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41/entry#A0A8V0ZH41-1", "sequence": { "sequence": "MGAEEEMLITLSGGAPWGFRLQGGSEQKRPLQVSKIRKRSKACRGGLWENDVLVSINGKSCAGLSHASAMQIIDSSNGMLNIRVKRTVGGDQTGPRLQRSPSPGQRVLSPPSPLSPTAQLLSSGPAGAPATTQSSQPRRPQRHLESLTSPPDSEAYYGETDSDADNVAQEKHRRARKKSPRSPPDSTNSKADVPQDEVSLSEQSGYESLPEAAVQEEAKDASCSGVAKREIACPPGSCADTPFSESEGQLRSSSTEGREPSPETMLLPHATKAIRAERHLIPMVGPVEHPVDEDLTTTYMEKAKQAKLHRHESIQEKNVKEAKTKCKTIASLLTDAPNPHSKGVLMFKKRRQRAKKYTLVSFGSVDEDRSYEEEDGIFPTSESEFDEEGFSDARSLTNHSDWDNTYLDIEKGKSDSEQKEEKQKGLSEASGKGARLFEQQRERAGKYTVEKVPAQRSPQLTPAAQPQPGMVNGDMPVPQKTASVPLSIHLEGVPSKMPATTPTQVLAPPSPTVFPHPPGTPDPFSSSTSMFNRSARPFTPGFSGQRPATSSVIFRPSVPKKPSESLGGQSTVVSPFSPLAPGTPTSAPAPTHRGPVSSSTSLYIPAPGRPTTPLESQPRAGGSGPETKPSASPARTSTASIFLSTPSKPGGEAASAASQPRVPGTASSSLYISPAPAQHMVSTSPLPVQLSANSAATPRPPSEPLTSREQRIAVPAPRTGILQEARRRGNKKPMFSKVEEKKNSPNPELLSLVQNLDEKPKGDHPGAGFESGPEEDFLSLGAEACNFMQSSGRKFKTPPPVAPKPQQQDGGLVNGAHDMPQLKGKGAQLFAKRQSRMDKFVVETATKPESKPRTPSPSPSLPSSWKYSPNIRAPPPIAYNPMHSPFYPLAASKSQASKAESKVKKAPGQKSGNKAIDVMHHQPYQLKSAMFCFGDPPSSSTQESPGQPGQQASSSFTAAKQIPVKTAKTQEIRRFSTPAPMPASSSLAPTVLVPRSATTLDEPVWRTEMASSAPATPAPFQMELSQSPKPYQSSPEFGQASLGPSPNPASASRFQVARPKFSAARTGMQANVWRPSFGHH", "length": 1080, "header": "tr|A0A8V0ZH41-1|A0A8V0ZH41_CHICK Isoform 1 of Synaptopodin 2-like protein OS=Gallus gallus OX=9031 GN=SYNPO2L PE=3 SV=1 CANONICAL=A0A8V0ZH41-1" }, "locus": { "chromosome": "6", "start_pos": 16781198, "end_pos": 16750091, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051417.1", "url": "https://www.ensembl.org/id/ENSGALT00010051417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030608.1", "url": "https://www.ensembl.org/id/ENSGALP00010030608.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1016, "start_aa": "Thr", "end_pos": 1016, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1016", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 512, "start_aa": "Thr", "end_pos": 512, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr512", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZSY9-1", "protein_name": "Synaptopodin 2-like protein", "gene_name": "Synpo2l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAEEEVQVTLAGGAPWGFRLQGGAEQRKPLQVSKIRRRSQAGRSGLRERDQLLSINGVSCTDFSHASAMTLIDASGHQLVLTVRRVAEEGSVRSPSPGELQMLSPLSPLSPEPPGAPVTQAPQPGSLRSPPDSEAYYGETDSDVDGPATHEKPRRTRRRGPPRPSLPGAPPDEVYLSDSPAEPAPVKTGSPSQGDSRVSSPSWEEGSALQPPPAEALLLPHGPLRPGPHLIPMVGPVPHPVAEDLTTTYTQKAKQATSTTFLNMETISQEPLSQASCDKDPAPELQDPFYAELQRAESLQEKSVKEAKTKCRTIASLLTAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGTEEEEDGIPPTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSGIAESQSSGLGGQLSEVSGRGVQLFEQQRQRVASSSQELAQVGPAAMLNGQSLQSPPRAQSAPPEAAVLPLSPLSAPAASPSPFQDGGAPSPAPSIFNRSARPFTPGLPGQRSGTTSVIFRPVAPKKVNEALGGTSPAPSPFAASLQGPTPLPSFTTVVPNRTPVSGTSSSTQRSSGPVTATSSLYIPAPSRPVTPGGAPEPPTPPSAAAMTSTASIFLSTPLRNSARPEAPGTAAPEPASAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPLGGRSYKTLSQVSPKTPPPMAPKTPPPMTPKTPPPVAPKPGSRGLPDGLVNGSTSMVGIPELPRLQGRGGELFAKRQSRADRYVVEATPGSSLNPGLRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPNKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEGPSTPASTSGPPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRAELASSPVPNPDHLESLRSFAATPTSCGFQVARPRFSATRTGLQAHVWRPGAGHH", "length": 1013 }, "evidence": [ { "id": "A0A8V0ZH41", "url": "https://omabrowser.org/oma/group/A0A8V0ZH41/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "U3JAM7-1", "protein_name": "Synaptopodin 2-like protein", "gene_name": "synpo2lb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVAEEVVVTLSGGAPWGFRLQGGAEHQKPLQVAKVRKRSKACRAGLRETDELLSINDVSCGSLSHAEAMNLIDSGRGTLHLRIKRAPAPYQSVVLVGRAPSPRIDKEYRAALRALSPPLSSKPSGVNRASLMSPTGLEWLTSPPDSEAYYGETDSDADVAAQERQRRQKRRSPSTSPAKIPGQTSPQEEETSGLSGYESTQDVMYPQTQSWPVPDVEGMGTLQKQVMHGVARREVVFQPQQNEWSQQGENSSENSDQSPSGAAEVDSGFQEPPTVPPPLVSPERAKEALMLASHRQMVPMVGPVDNPVDEELTVTYMDKARQAKLHRGESLQDKQVKEARSKCRTIASLLTDAPNPHSKGVLMFKKRRQRAKKYTLTCFGSVDGESNSNTEGETEDESLFPGSESELDEDGFSAAPDPTWDSGYLDVLDKRTSACIVPDREAEISPGLNATSGKGAQLFEQQRKRAEEHVSNLNTFSMPQHQGDSTLTYTPVAPYTPQSTSSLSTSMVNGEPLVVSRTSVVLSSPGQTPMPSLTGALPEQIDSSAASSVHNRTARPFAPGCVSNRAATAPVVFRPSPAKKAGSQSQAVSVATLPAAFSPVVSEGKKAISTSSLYIPARPATYNGPSSLLSPSSVISSPFSPPPSNAPLYSPTYSSTSAPFSPTTSHVTSLSLPSGMAQTYSQPQAMPFSPPHPTVSSQFQPPPPVNVPAQPFSSSFMNAPGFPNVPVHPPTSLNMQPSPSHKVSFNPYISVASTTPETPNAPIAQQYPLSNSTDGISSREQRLSVPAGRTGILQEACRRSTKKPMFSAQEEKKAPSFNPELLSLVQNFDDRSRSGVEAGFESGPEEDFLNLGAEACNFMQAQKNRLPPPVAPKPGHPAPEMPQMRGKGAELFARRQSRMDRYVVDKQPKSPAQPRDPSPTPSLPGNWKYSPNIRAPPPINYNPLLSPSCPLVAQRSTKANDATKVGVKTMHGHNKQGIKALDFVSKQPYQLNPSLFSYGANPQNNTTCQQQQQNGVGITGQFLNPPKQVPIKAGRVYEIKRFSTPTPMSAPTSLTPTVIAPRSATTLGEPMWRSDVTSPPPVAPRPAAPFSPPPPAPTAALPALPKISSAANSGPITQPNQGQAYTPFQTAKQFKSAPELSPLSAGVRSSGSASGLNLRVPRPRFCTSSMGLQPNVWRPGSIHY", "length": 1184 }, "evidence": [ { "id": "A0A8V0ZH41", "url": "https://omabrowser.org/oma/group/A0A8V0ZH41/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of actin filament bundle assembly", "id": "GO:0032233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZH41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH41" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 88, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 512, 1016 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 398, "end_pos": 400 }, { "start_pos": 532, "end_pos": 534 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": 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"tr|A0A8V0ZH60-1|A0A8V0ZIL3_CHICK Computationally mapped isoform of FEV transcription factor, ETS family member OS=Gallus gallus OX=9031 GN=FEV PE=3 SV=1 CANONICAL=A0A8V0ZIL3-1" }, "locus": { "chromosome": "7", "start_pos": 21982544, "end_pos": 21981128, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051437.1", "url": "https://www.ensembl.org/id/ENSGALT00010051437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030628.1", "url": "https://www.ensembl.org/id/ENSGALP00010030628.1" } ] } }, { "isoform_ac": "A0A8V0ZH65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL3/entry#A0A8V0ZH65-1", "sequence": { "sequence": "KLPQLWQKSDFLFPGRVSWLHHSGEVGEGERPGGHSPAWPQLSPHPHPFFPTDPVGETLFKDGKSQAWGSLNPSVQKGSGQIQLWQFLLELLSDRANLNCIAWEGTNGEFKLIDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGLAQVCQPAAPDHTLYKFQGNLAPLPFSGISKLNLMTSGVTPAGFSYWPGSSPSLYPGHSLQPSAPFSAMAASHLNNMNNHYH", "length": 247, "header": "tr|A0A8V0ZH65-1|A0A8V0ZH65_CHICK Computationally mapped isoform of FEV transcription factor, ETS family member OS=Gallus gallus OX=9031 GN=FEV PE=3 SV=1 CANONICAL=A0A8V0ZIL3-1" }, "locus": { "chromosome": "7", "start_pos": 21982544, "end_pos": 21980071, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051442.1", "url": "https://www.ensembl.org/id/ENSGALT00010051442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030633.1", "url": "https://www.ensembl.org/id/ENSGALP00010030633.1" } ] } }, { "isoform_ac": "A0A8V0ZIL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL3/entry#A0A8V0ZIL3-1", "sequence": { "sequence": "HPSFTPIHPSLRYSVHPPILPLCPLSLSPLSLPSPYLSLRGFLFLYKSFPSSGRNRISFFLDAFPGFTTAVRSSGGNFVQRRQEPGVGIPQPERAESGQIQLWQFLLELLSDRANLNCIAWEGTNGEFKLIDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGLAQVCQPAAPDHTLYKFQGNLAPLPFSGISKLNLMTSGVTPAGFSYWPGSSPSLYPGHSLQPSAPFSAMAASHLNNMNNHYH", "length": 265, "header": "tr|A0A8V0ZIL3-1|A0A8V0ZIL3_CHICK Isoform 1 of FEV transcription factor, ETS family member OS=Gallus gallus OX=9031 GN=FEV PE=3 SV=1 CANONICAL=A0A8V0ZIL3-1" }, "locus": { "chromosome": "7", "start_pos": 21982544, "end_pos": 21979931, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051439.1", "url": "https://www.ensembl.org/id/ENSGALT00010051439.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030630.1", "url": "https://www.ensembl.org/id/ENSGALP00010030630.1" } ] } }, { "isoform_ac": "A0A8V0ZIL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL3/entry#A0A8V0ZIL9-1", "sequence": { "sequence": "MWCWDGSRYYAKTSELSIQQAGTRWDMGRDGKAAVRVVGTFPAPPALTGSSDLSGAGSGQIQLWQFLLELLSDRANLNCIAWEGTNGEFKLIDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFDFHGLAQVCQPAAPDHTLYKFQGNLAPLPFSGISKLNLMTSGVTPAGFSYWPGSSPSLYPGHSLQPSAPFSAMAASHLNNMNNHYH", "length": 226, "header": "tr|A0A8V0ZIL9-1|A0A8V0ZIL9_CHICK Computationally mapped isoform of FEV transcription factor, ETS family member OS=Gallus gallus OX=9031 GN=FEV PE=3 SV=1 CANONICAL=A0A8V0ZIL3-1" }, "locus": { "chromosome": "7", "start_pos": 21982544, "end_pos": 21981867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051444.1", "url": "https://www.ensembl.org/id/ENSGALT00010051444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030635.1", "url": "https://www.ensembl.org/id/ENSGALP00010030635.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 223, "start_aa": "Thr", "end_pos": 223, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr223", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" 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"https://www.uniprot.org/uniprotkb/A0A8V0ZH69", "locus": { "chromosome": "5", "start_pos": 8573459, "end_pos": 8560829, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021064", "url": "https://www.ensembl.org/id/ENSGALG00010021064" } ] } } ], "crossref": [ { "id": "A0A8V0ZH69", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZH69", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005643", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005643", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423038", "url": "https://www.ncbi.nlm.nih.gov/gene/423038", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423038", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423038", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ILPNPKC", "url": "https://omabrowser.org/oma/group/ILPNPKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH69", "url": "https://www.orthodb.org/?gene=A0A8V0ZH69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C9I1", "url": "https://www.orthodb.org/?gene=E1C9I1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10225", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10225", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10225:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10225:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2142845", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142845", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2160916", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2160916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C9I1", "url": "https://www.uniprot.org/uniprotkb/E1C9I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C9I1-1", "url": "https://www.uniprot.org/uniprotkb/E1C9I1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTYFGVTSAVLSVWVMTFMAQNYFITELKETCTRTLWFISRTGTLVSGSTLSPCRITGVGLYLGHKVNFSEASNVCNRLNLQLASKEQVEKALNHGFETCSSGWIKDGSVAIPRITSNMKCGKGSVGLVNWRPNHAHKFTVYCFNSSDVQINSCKPDPTTTIIPSSSVPTDLTAYSSSDLTGNTTAVPTAAEPEQTLKNVKFRIICITETILPTEETTTTMPEESYTYPAAFRNDGVVFGGIPTALLVLAIIFFISSVLLAVCYIKKYKKCLLFSRKNQKKEVVETTALKDTASNDKILEKETKNNGKMVEEATAKPETTVKCLEVEV", "length": 329, "header": "tr|A0A8V0ZH69-1|A0A8V0ZH69_CHICK Isoform 1 of Lymphatic vessel endothelial hyaluronan receptor 1 OS=Gallus gallus OX=9031 GN=LYVE1 PE=4 SV=1 CANONICAL=A0A8V0ZH69-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZH69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69/entry#A0A8V0ZH69-1", "sequence": { "sequence": "MTTYFGVTSAVLSVWVMTFMAQNYFITELKETCTRTLWFISRTGTLVSGSTLSPCRITGVGLYLGHKVNFSEASNVCNRLNLQLASKEQVEKALNHGFETCSSGWIKDGSVAIPRITSNMKCGKGSVGLVNWRPNHAHKFTVYCFNSSDVQINSCKPDPTTTIIPSSSVPTDLTAYSSSDLTGNTTAVPTAAEPEQTLKNVKFRIICITETILPTEETTTTMPEESYTYPAAFRNDGVVFGGIPTALLVLAIIFFISSVLLAVCYIKKYKKCLLFSRKNQKKEVVETTALKDTASNDKILEKETKNNGKMVEEATAKPETTVKCLEVEV", "length": 329, "header": "tr|A0A8V0ZH69-1|A0A8V0ZH69_CHICK Isoform 1 of Lymphatic vessel endothelial hyaluronan receptor 1 OS=Gallus gallus OX=9031 GN=LYVE1 PE=4 SV=1 CANONICAL=A0A8V0ZH69-1" }, "locus": { "chromosome": "5", "start_pos": 8573056, "end_pos": 8563034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050957.1", "url": "https://www.ensembl.org/id/ENSGALT00010050957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030148.1", "url": "https://www.ensembl.org/id/ENSGALP00010030148.1" } ] } }, { "isoform_ac": "E1C9I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69/entry#E1C9I1-1", "sequence": { "sequence": "MTTYFGVTSAVLSVWVMTFMAQNYFITGSTLSPCRITGVGLYLGHKVNFSEASNVCNRLNLQLASKEQVEKALNHGFETCSSGWIKDGSVAIPRITSNMKCGKGSVGLVNWRPNHAHKFTVYCFNSSDVQINSCKPDPTTTIIPSSSVPTDLTAYSSSDLTGNTTAVPTAAEPEQTLKNVKFRIICITETILPTEETTTTMPEESYTYPAAFRNDGVVFGGIPTALLVLAIIFFISSVLLAVCYIKKYKKCLLFSRKNQKKEVVETTALKDTASNDKILEKETKNNGKMVEEATAKPETTVKCLEVEV", "length": 308, "header": "tr|E1C9I1-1|A0A8V0ZH69_CHICK Computationally mapped isoform of Lymphatic vessel endothelial hyaluronan receptor 1 OS=Gallus gallus OX=9031 GN=LYVE1 PE=4 SV=2 CANONICAL=A0A8V0ZH69-1" }, "locus": { "chromosome": "5", "start_pos": 8573056, "end_pos": 8563034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050961.1", "url": "https://www.ensembl.org/id/ENSGALT00010050961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030152.1", "url": "https://www.ensembl.org/id/ENSGALP00010030152.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423038", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423038", "resource": "KEGG Pathway" }, { "id": "R-GGA-2142845", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2142845", "resource": "Reactome", "description": "Hyaluronan metabolism" }, { "id": "R-GGA-2160916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2160916", "resource": "Reactome", "description": "Hyaluronan degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FTE1-1", "protein_name": "Lymphatic vessel endothelial hyaluronic acid receptor 1", "gene_name": "Lyve1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFKHFSLVLLLTSTWTTRLPVQGTIRVQELSISTCRYMGVALVGKKANPQMNFTEAGEVCKVLGLTLASKDQVEAAQKSGFETCSYGWVGERITVIPRIFPNPKCGKNGIGVLIWKAMPSTKFKAYCHNSSDTWANSCIPEIITTFDPTFDTQTPEMEFSVSNSAYSASSPDFTTHAPTTTRAPPSTSMAWKTKKICFTEVYTEPNTVAAETEPPVESGAAFKNEAPGFGGVPTTLLVLALLFFAAAAVLAVCYVKRYVKAFPFTNKNQKKEMIETKVVKEEKADDINSNEESKKTDKNLEELKSPPKTTVRCLEAEV", "length": 318 }, "evidence": [ { "id": "A0A8V0ZH69", "url": "https://omabrowser.org/oma/group/A0A8V0ZH69/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LTD0-1", "protein_name": "Lymphatic vessel endothelial hyaluronic acid receptor 1", "gene_name": "LYVE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMAKYFNLLLLLASLWTTRLLVQGALRTEELSISGPCRIMGVTLVNKNTQSQLNFTEAQEACRLVGLTLASKDQVEAARKSGFETCSYGWVKDQFLVIPRIYPNPKCGKNGKGVLVWRHSLSQKFKAYCHNSSDTRTNSCIPEIIPTNDPTFNTNTAPYTTEMTVNDRTSSSSTNGPSSSVMSTVATTSLPLATTSTPRKRKLICITEAFMETSTISTETELYIENRTAFKNEAIGFGGIPTALLVLALLFFAAAAGLAVCYVKRYVKAFPFTNKNQQKEMIETKVVKEEKADDNNLNEESKTLDKKPEELKSPPKTTVRCLEAEV", "length": 326 }, "evidence": [ { "id": "A0A8V0ZH69", "url": "https://omabrowser.org/oma/group/A0A8V0ZH69/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6UC88-1", "protein_name": "Lymphatic vessel endothelial hyaluronic acid receptor 1", "gene_name": "LYVE1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKFFSLGLLLASIWTTRLLVQGSLRSEEISILGPCRIMGVTLVTKKTQPLLNFTEAQEACRLVGLTLASQDQVEEARKFGFETCSYGWVKNQFVVIPRIISNPKCGKSGVGVVIWRSSLSSRHRSYCHNSSDIWINSCLPEIITTDDPLFNTETATYTTKLMVSDSTHSELSTDGPDYVTTTVAPPLASTSTPRKRKLICITEAFMDTSAVATERESDIQNRPAFKNEAVGFGGVPTALLVLALLFFAAAAGLAVCYVKRYVKAFPFTNKNQQKEMIETKVVKEEKADDSNPNEESKKMNKTPEEPKSPPKTTVRCLEAEV", "length": 322 }, "evidence": [ { "id": "A0A8V0ZH69", "url": "https://omabrowser.org/oma/group/A0A8V0ZH69/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BHC0-1", "protein_name": "Lymphatic vessel endothelial hyaluronic acid receptor 1", "gene_name": "Lyve1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQHTSLVLLLASIWTTRHPVQGADLVQDLSISTCRIMGVALVGRNKNPQMNFTEANEACKMLGLTLASRDQVESAQKSGFETCSYGWVGEQFSVIPRIFSNPRCGKNGKGVLIWNAPSSQKFKAYCHNSSDTWVNSCIPEIVTTFYPVLDTQTPATEFSVSSSAYLASSPDSTTPVSATTRAPPLTSMARKTKKICITEVYTEPITMATETEAFVASGAAFKNEAAGFGGVPTALLVLALLFFGAAAVLAVCYVKRYVKAFPFTTKNQQKEMIETKVVKEEKADDVNANEESKKTIKNPEEAKSPPKTTVRCLEAEV", "length": 318 }, "evidence": [ { "id": "A0A8V0ZH69", "url": "https://omabrowser.org/oma/group/A0A8V0ZH69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5Y7-1", "protein_name": "Lymphatic vessel endothelial hyaluronic acid receptor 1", "gene_name": "LYVE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARCFSLVLLLTSIWTTRLLVQGSLRAEELSIQVSCRIMGITLVSKKANQQLNFTEAKEACRLLGLSLAGKDQVETALKASFETCSYGWVGDGFVVISRISPNPKCGKNGVGVLIWKVPVSRQFAAYCYNSSDTWTNSCIPEIITTKDPIFNTQTATQTTEFIVSDSTYSVASPYSTIPAPTTTPPAPASTSIPRRKKLICVTEVFMETSTMSTETEPFVENKAAFKNEAAGFGGVPTALLVLALLFFGAAAGLGFCYVKRYVKAFPFTNKNQQKEMIETKVVKEEKANDSNPNEESKKTDKNPEESKSPSKTTVRCLEAEV", "length": 322 }, "evidence": [ { "id": "A0A8V0ZH69", "url": "https://omabrowser.org/oma/group/A0A8V0ZH69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69" } ], "pmid": "" }, { "name": "hyaluronic acid binding", "id": "GO:0005540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69" } ], "pmid": "" }, { "name": "cargo receptor activity", "id": "GO:0038024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69" } ], "pmid": "" }, { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69" } ], "pmid": "" }, { "name": "hyaluronan catabolic process", "id": "GO:0030214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030214", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69" } ], "pmid": "" }, { "name": "positive regulation of cellular extravasation", "id": "GO:0002693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": 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"isoform_ac": "A0A8V0ZH81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81/entry#A0A8V0ZH81-1", "sequence": { "sequence": "MAAASSSSSSAAGCRDGPVGPGWSDSQFRHYSFETRPIPRLSHSDPRAEELIENEEPVVLTDTNLVYPALKWDLDYLQENIGNGDFSVYSASTHKFLYYDEKKMANFKNFKPKSSREEMKFAEFVDRLQEIQQKGSAERLYLQQTLNDTVGRKIVVDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYEKFPNFRSVVGYETVVGPGDVLYIPMWHHIESLLNGGITITVNFWYKGAPTPKRIEYPLKAHQKVAIMRNIEKMLGEALGSPQEVGPLLNMMIKGRYD", "length": 343, "header": "tr|A0A8V0ZH81-1|A0A8V0ZH81_CHICK Isoform 1 of Hypoxia-inducible factor 1-alpha inhibitor OS=Gallus gallus OX=9031 GN=HIF1AN PE=1 SV=1 CANONICAL=A0A8V0ZH81-1" }, "locus": { "chromosome": "6", "start_pos": 18179038, "end_pos": 18171533, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050989.1", "url": "https://www.ensembl.org/id/ENSGALT00010050989.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030179.1", "url": "https://www.ensembl.org/id/ENSGALP00010030179.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-1234174", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1234174", "resource": "Reactome", "description": "Cellular response to hypoxia" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "negative regulation of Notch signaling pathway", "id": "GO:0045746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045746", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "regulation of vascular endothelial growth factor receptor signaling pathway", "id": "GO:0030947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030947", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "positive regulation of myoblast differentiation", "id": "GO:0045663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045663", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 11, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "carboxylic acid binding", "id": "GO:0031406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031406", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "NF-kappaB binding", "id": "GO:0051059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "peptidyl-histidine dioxygenase activity", "id": "GO:0036139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "[protein]-asparagine 3-dioxygenase activity", "id": "GO:0036140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036140", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "ankyrin repeat binding", "id": "GO:0071532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071532", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" }, { "name": "peptidyl-aspartic acid 3-dioxygenase activity", "id": "GO:0062101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062101", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZH81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "54264", "name": "", "equation": "L-histidyl-[ankyrin-repeat domain protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-histidyl-[ankyrin-repeat domain protein] + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZH81-1" ], "evidence": [ { "id": "54264", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54264" } ] }, { "id": "54268", "name": "", "equation": "L-asparaginyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-asparaginyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZH81-1" ], "evidence": [ { "id": "54268", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54268" } ] }, { "id": "54272", "name": "", "equation": "L-asparaginyl-[ankyrin-repeat domain protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-asparaginyl-[ankyrin-repeat domain protein] + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZH81-1" ], "evidence": [ { "id": "54272", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54272" } ] }, { "id": "54280", "name": "", "equation": "L-aspartyl-[ankyrin-repeat domain protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-aspartyl-[ankyrin-repeat domain protein] + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZH81-1" ], "evidence": [ { "id": "54280", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54280" } ] }, { "id": "R-GGA-1234164", "name": "Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZH81-1" ], "evidence": [ { "id": "R-GGA-1234164", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1234164" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZH81", "gene_name": "HIF1AN", "activity": [ { "ec_number": "1.14.11.30", "activity": "L-asparaginyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-asparaginyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "A0A8V0ZH81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ] }, { "ec_number": "1.14.11.n4", "activity": "L-aspartyl-[ankyrin-repeat domain protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-aspartyl-[ankyrin-repeat domain protein] + succinate + CO2.", "evidence": [ { "id": "A0A8V0ZH81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ] }, { "ec_number": "1.14.11.n4", "activity": "", "evidence": [ { "id": "A0A8V0ZH81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ] }, { "ec_number": "1.14.11.30", "activity": "", "evidence": [ { "id": "A0A8V0ZH81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZH81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH81" }, { "id": "PS51184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "JmjC", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 306, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.30", "ec_name": "L-asparaginyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-asparaginyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2.", "evidence": [ { "id": "1.14.11.30", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.30" }, { "id": "1.14.11.30", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.30" } ] }, { "ec_number": "1.14.11.n4", "ec_name": "L-aspartyl-[ankyrin-repeat domain protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-aspartyl-[ankyrin-repeat domain protein] + succinate + CO2.", "evidence": [ { "id": "1.14.11.n4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.n4" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 190, "end_pos": 192 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"https://www.ensembl.org/id/ENSGALP00010030656.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZIP2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ISLR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP2", "locus": { "chromosome": "10", "start_pos": 2629764, "end_pos": 2637179, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021234", "url": "https://www.ensembl.org/id/ENSGALG00010021234" } ] } } ], "crossref": [ { "id": "A0A8V0ZIP2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIP2", "database": "AlphaFoldDB", "categories": [] }, { "id": "429941", "url": "https://www.ncbi.nlm.nih.gov/gene/429941", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429941", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429941", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHSMVQW", "url": "https://omabrowser.org/oma/group/GHSMVQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH88", "url": "https://www.orthodb.org/?gene=A0A8V0ZH88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIP2", "url": "https://www.orthodb.org/?gene=A0A8V0ZIP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPK6", "url": "https://www.orthodb.org/?gene=A0A8V0ZPK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZH88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPK6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRGAGRRQWGASPPPLSGRQGTGRAPTQPLCPLAGDMAPALWLWLAALLGSARACPEPCACVDKYAHQFADCAYKDLQVVPTGLPSNVTTLSLSANKITALQRRSFVEVTQVTSLWLAHNEIRAIEPGAFAILVQLKNLDISHNQIVDFPWQDLYNLSALQLLKMNNNHMAVVPQGAFHTLKDLRSLRINNNKFTTLAEGIFDSLSSLSHLQIYNNPFECSCKLQWLKKWMDSTLISIPEKESITCSLPEQLRGVEVGKIPDTQCTSPSVQLTYYPNLDTTELFDGFTLTLHCAVTGAPPPEVSWKIRTSSQTLELSGSPSESAGKDPPRQDPERFLVFKNGTLVIPHLSKREEGTYTCLATNEMGSNQTSVNVAVAGSQKYPLQPGRDPTGGKAQPGDKKPGAKGAKNSVLTPDERSKPLSPTRQSQPPSAAGMEPTGDGKVPFQLPPFEKKCGSMPTSRYISNHAFNQSGDFKQHTFDLGVIALDVSERDARVQLTPTYVQPDKVHLRMLYLCQESSRGHALVQWSKIEEGVNSYWFQGLKPGTNYSVCLTYLGEDCQVQVVFTTKKEIPSLIIIVVVSIFLLLLATLPLMGATWCHLLSKYQGKTYKLIMKAQNPDQMEKHMAADFDPRASYLESEKNYNPSEVGEGEAEEEDEDEEDDDEGGRRRRRREAEETTELEREESVAASSMAESQSKANGEEFEVRSEYSDKLPLGAEAVTISQEINGNYRQRPR", "length": 736, "header": "tr|A0A8V0ZIP2-1|A0A8V0ZIP2_CHICK Isoform 1 of Immunoglobulin superfamily containing leucine rich repeat 2 OS=Gallus gallus OX=9031 GN=ISLR2 PE=4 SV=1 CANONICAL=A0A8V0ZIP2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZH88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP2/entry#A0A8V0ZH88-1", "sequence": { "sequence": "MAPALWLWLAALLGSARACPEPCACVDKYAHQFADCAYKDLQVVPTGLPSNVTTLSLSANKITALQRRSFVEVTQVTSLWLAHNEIRAIEPGAFAILVQLKNLDISHNQIVDFPWQDLYNLSALQLLKMNNNHMAVVPQGAFHTLKDLRSLRINNNKFTTLAEGIFDSLSSLSHLQIYNNPFECSCKLQWLKKWMDSTLISIPEKESITCSLPEQLRGVEVGKIPDTQCTSPSVQLTYYPNLDTTELFDGFTLTLHCAVTGAPPPEVSWKIRTSSQTLELSGSPSESAGKDPPRQDPERFLVFKNGTLVIPHLSKREEGTYTCLATNEMGSNQTSVNVAVAGSQKYPLQPGRDPTGGKAQPGDKKPGAKGAKNSVLTPDERSKPLSPTRQSQPPSAAGMEPTGDGKVPFQLPPFEKKCGSMPTSRYISNHAFNQSGDFKQHTFDLGVIALDVSERDARVQLTPTYVQPDKVHLRMLYLCQESSRGHALVQWSKIEEGVNSYWFQGLKPGTNYSVCLTYLGEDCQVQVVFTTKKEIPSLIIIVVVSIFLLLLATLPLMGATWCHLLSKYQGKTYKLIMKAQNPDQMEKHMAADFDPRASYLESEKNYNPSEVGEGEAEEEDEDEEDDDEGGRRRRRREAEETTELEREESVAASSMAESQSKANGEEFEVRSEYSDKLPLGAEAVTISQEINGNYRQRPR", "length": 699, "header": "tr|A0A8V0ZH88-1|A0A8V0ZIP2_CHICK Computationally mapped isoform of Immunoglobulin superfamily containing leucine rich repeat 2 OS=Gallus gallus OX=9031 GN=ISLR2 PE=4 SV=1 CANONICAL=A0A8V0ZIP2-1" }, "locus": { "chromosome": "10", "start_pos": 2634354, "end_pos": 2632258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051469.1", "url": "https://www.ensembl.org/id/ENSGALT00010051469.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030659.1", "url": "https://www.ensembl.org/id/ENSGALP00010030659.1" } ] } }, { "isoform_ac": "A0A8V0ZIP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP2/entry#A0A8V0ZIP2-1", "sequence": { "sequence": "MLRGAGRRQWGASPPPLSGRQGTGRAPTQPLCPLAGDMAPALWLWLAALLGSARACPEPCACVDKYAHQFADCAYKDLQVVPTGLPSNVTTLSLSANKITALQRRSFVEVTQVTSLWLAHNEIRAIEPGAFAILVQLKNLDISHNQIVDFPWQDLYNLSALQLLKMNNNHMAVVPQGAFHTLKDLRSLRINNNKFTTLAEGIFDSLSSLSHLQIYNNPFECSCKLQWLKKWMDSTLISIPEKESITCSLPEQLRGVEVGKIPDTQCTSPSVQLTYYPNLDTTELFDGFTLTLHCAVTGAPPPEVSWKIRTSSQTLELSGSPSESAGKDPPRQDPERFLVFKNGTLVIPHLSKREEGTYTCLATNEMGSNQTSVNVAVAGSQKYPLQPGRDPTGGKAQPGDKKPGAKGAKNSVLTPDERSKPLSPTRQSQPPSAAGMEPTGDGKVPFQLPPFEKKCGSMPTSRYISNHAFNQSGDFKQHTFDLGVIALDVSERDARVQLTPTYVQPDKVHLRMLYLCQESSRGHALVQWSKIEEGVNSYWFQGLKPGTNYSVCLTYLGEDCQVQVVFTTKKEIPSLIIIVVVSIFLLLLATLPLMGATWCHLLSKYQGKTYKLIMKAQNPDQMEKHMAADFDPRASYLESEKNYNPSEVGEGEAEEEDEDEEDDDEGGRRRRRREAEETTELEREESVAASSMAESQSKANGEEFEVRSEYSDKLPLGAEAVTISQEINGNYRQRPR", "length": 736, "header": "tr|A0A8V0ZIP2-1|A0A8V0ZIP2_CHICK Isoform 1 of Immunoglobulin superfamily containing leucine rich repeat 2 OS=Gallus gallus OX=9031 GN=ISLR2 PE=4 SV=1 CANONICAL=A0A8V0ZIP2-1" }, "locus": { "chromosome": "10", "start_pos": 2634465, "end_pos": 2632258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051470.1", "url": "https://www.ensembl.org/id/ENSGALT00010051470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030661.1", "url": "https://www.ensembl.org/id/ENSGALP00010030661.1" } ] } }, { "isoform_ac": "A0A8V0ZPK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP2/entry#A0A8V0ZPK6-1", "sequence": { "sequence": "MAPALWLWLAALLGSARACPEPCACVDKYAHQFADCAYKDLQVVPTGLPSNVTTLSLSANKITALQRRSFVEVTQVTSLWLAHNEIRAIEPGAFAILVQLKNLDISHNQIVDFPWQDLYNLSALQLLKMNNNHMAVVPQGAFHTLKDLRSLRINNNKFTTLAEGIFDSLSSLSHLQIYNNPFECSCKLQWLKKWMDSTLISIPEKESITCSLPEQLRGVEVGKIPDTQCTSPSVQLTYYPNLDTTELFDGFTLTLHCAVTGAPPPEVSWKIRTSSQTLELSGSPSESAGKDPPRQDPERFLVFKNGTLVIPHLSKREEGTYTCLATNEMGSNQTSVNVAVAGSQKYPLQPGRDPTGGKAQPGDKKPGAKGAKNSVLTPDERSKPLSPTRQSQPPSAAGMEPTGDGKVPFQLPPFEKKCGSMPTSRYISNHAFNQSGDFKQHTFDLGVIALDVSERDARVQLTPTYVQPDKVHLRMLYLCQESSRGHALVQWSKIEEGVNSYWFQGLKPGTNYSVCLTYLGEDCQVQVVFTTKKEIPSLIIIVGEGEAEEEDEDEEDDDEGGRRRRRREAEETTELEREESVAASSMAESQSKANGEEFEVRSEYSDKLPLGAEAVTISQEINGNYRQRPR", "length": 630, "header": "tr|A0A8V0ZPK6-1|A0A8V0ZPK6_CHICK Computationally mapped isoform of Immunoglobulin superfamily containing leucine rich repeat 2 OS=Gallus gallus OX=9031 GN=ISLR2 PE=4 SV=1 CANONICAL=A0A8V0ZIP2-1" }, "locus": { "chromosome": "10", "start_pos": 2634354, "end_pos": 2632258, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051467.1", "url": "https://www.ensembl.org/id/ENSGALT00010051467.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030658.1", "url": "https://www.ensembl.org/id/ENSGALP00010030658.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429941", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429941", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R4G0-1", "protein_name": "Immunoglobulin superfamily containing leucine-rich repeat protein 2", "gene_name": "Islr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMGPFGSLCLAWALLGVARACPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHNLISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLEPGTFDALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVSLPEPDSIACASPPELQGVPVHRLPALPCAPPSVRLSAEPPPEAPGTPLRAGLSFLLHCVAEGHPTPRLQWQLQIPGGTVVLVPPVLSKEEDGGEKVDDGEGDGDEDQPTQTEAPTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGIYTCRAHNELGTNSTSLRVTVAAAGPPKHAPGTGEEPDAQAPTSERKATTKGRSNSVLPFKPEGKTKGQGLARVSILGETEAELEETDEEEQMGGQIPADPMGEKHCGHGDPSRYVSNHAFNQSSDLKPHVFELGVIALDVAEREARVQLTPLAARWGPGPDGASGARRPGRRPLRLLYLCPAGGGTAVQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVTVSVFLLVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPARGEAGGEEPEEVPEEGLDEDVEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYSDRLPLGAEAVNIAQEINGNYRQTAG", "length": 746 }, "evidence": [ { "id": "A0A8V0ZIP2", "url": "https://omabrowser.org/oma/group/A0A8V0ZIP2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5RKR3-1", "protein_name": "Immunoglobulin superfamily containing leucine-rich repeat protein 2", "gene_name": "Islr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPFGALCLAWALLGVVRACPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQLKNLDLSHNLISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLEPGTFDALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVSLPEPDSIACASPPELQGVPVHRLPALPCAPPSVRLSAEPPPEAPGTPLRAGLAFMLHCVAEGHPTPRLQWQLQIPGGTVVLVPPVLSKEEDGGDKVEDGEGDGDEDLPTQTEAPTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGIYTCRAHNELGTNSTSLRVTVAAAGPPKHAPGTGEEPDAQVPTSERKATTKGRSNSVLPFKPEGKTKGQGLARVSVLGEIEAELEETDEGEQMEGQIPADPMGEKHCGHGDPSRYVSNHAFNQSSDLKPHVFELGVIALDVAEREARVQLTPLAARWGPGPDGASGARRPGRRPLRLLYLCPAGGGTAVQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVTVSVFLLVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPARGEAGGEEPEEVPEEGLDEDVEQGDPSGDLQREESLAGCSLVESQSKANQEEFEAGSEYSDRLPLGAEAVNIAQEINGNYRQTAG", "length": 745 }, "evidence": [ { "id": "A0A8V0ZIP2", "url": "https://omabrowser.org/oma/group/A0A8V0ZIP2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UXK2-1", "protein_name": "Immunoglobulin superfamily containing leucine-rich repeat protein 2", "gene_name": "ISLR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFPLRALWLVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPVYRLPALPCAPPSVHLSAEPPLEAPGTPLRAGLAFVLHCIADGHPTPRLQWQLQIPGGTVVLEPPVLSGEDDGVGAEEGEGEGDGDLLTQTQAQTPTPAPAWPAPPATPRFLALANGSLLVPLLSAKEAGVYTCRAHNELGANSTSIRVAVAATGPPKHAPGAGGEPDGQAPTSERKSTAKGRGNSVLPSKPEGKIKGQGLAKVSILGETETEPEEDTSEGEEAEDQILADPAEEQRCGNGDPSRYVSNHAFNQSAELKPHVFELGVIALDVAEREARVQLTPLAARWGPGPGGAGGAPRPGRRPLRLLYLCPAGGGAAVQWSRVEEGVNAYWFRGLRPGTNYSVCLALAGEACHVQVVFSTKKELPSLLVIVAVSVFLLVLATVPLLGAACCHLLAKHPGKPYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPAGGEAGGEEPEDVQGEGLDEDAEQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYSDRLPLGAEAVNIAQEINGNYRQTAG", "length": 745 }, "evidence": [ { "id": "A0A8V0ZIP2", "url": "https://omabrowser.org/oma/group/A0A8V0ZIP2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 269, "end_pos": 376, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"https://www.uniprot.org/uniprotkb/A0A8V0ZHB8", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZHB8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHB8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR48071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48071:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48071:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z425", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z425", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z425-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z425-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTGIPRHPPPPCPLFVAPVEPTGVPTAVPSNASAEPGENGHPPAGQRARGPPRHPHPELPAGPWDTAVLRLAGGSHPCEGAVQVQHRGLWMPVCRDSWSAAASRELCRRLRCGDAEGDAVAVSPDGDGDAAEGCPTAPANCSGWEPRLCAPVLRLAGGRSRCEGRVELRQAGSWGTVCDDGWDLADAAVVCRQLGCGWALRAPREAAFGRGRGPVLRDEVKCGGHEERLAECPAALQHDCSHKEDAGVVCSEHHEWRLSGGKDGCAGRVEVRYRGTWSTVCDSTWYELEAAVLCRTLGCGEPLQRPSFRHTLPTKMLYECVDLQPSLAYCRWTYNKSAPCHESRAAGVVCNGTAPFGPTRRGLGQRPPPPRVVRLQPSPLSPISSANPSSPPSPSCPVSPAAPPALLVAATPSLSLPADPTPATVPTTKGSDSSDSDYEHYDFSSKPPVALSTFHSENPPFLPSGHLPSMLGSPTDPAPPTPQTPSADSRVSSCCCPARMGWSHFPQRVRQPRPPVPQLPVCPSRGGYMVALCSPSDMHPVFPQCRPRSVPSRGAGRGTHPLPPLPPPWSPTVVRAQPPRVPGPARNPHRAAPTSTQHPPVRGLKRLQGWGRPWGWRWQDPLGGESSGDGSGVGETLRDGDSPRRMWGPQGAAGGPGGAHTAPAFPSTPSRALHAHPSAQHAVGTTTPGRPRPR", "length": 695, "header": "tr|A0A8V0ZHB8-1|A0A8V0ZHB8_CHICK Isoform 1 of T-cell differentiation antigen CD6 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZHB8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z425-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB8/entry#A0A8V0Z425-1", "sequence": { "sequence": "MGTGIPRHPPPPCPLFVAPVEPTGVPTAVPSNASAEPGENGHPPAGQRARGPPRHPHPELPAGPWDTAVLRLAGGSHPCEGAVQVQHRGLWMPVCRDSWSAAASRELCRRLRCGDAEGDAVAVSPDGDGDAAEGCPTAPANCSGWEPRLCQLQMATEPGCCAAGQASVTCAPVLRLAGGRSRCEGRVELRQAGSWGTVCDDGWDLADAAVVCRQLGCGWALRAPREAAFGRGRGPVLRDEVKCGGHEERLAECPAALQHDCSHKEDAGVVCSEHHEWRLSGGKDGCAGRVEVRYRGTWSTVCDSTWYELEAAVLCRTLGCGEPLQRPSFRHTLPTKMLYECVDLQPSLAYCRWTYNKSAPCHESRAAGVVCNGTAPFVLSSPISSANPSSPPSPSCPVSPAAPPALLVAATPSLSLPADPTPATVPTTKGSDSSDSDYEHYDFSSKPPVALSTFHSENPPFLPSGHLPSMLGSPTDPAPPTPQTPSADSRVSSCCCPLLPSPAPPAVPCMPTPVLNTPWVPPPPADPDHADSSSTSSGEWYENVQGTEACGDPPLGEHTRDPSFSEGSDYDDIQGSDC", "length": 578, "header": "tr|A0A8V0Z425-1|A0A8V0Z425_CHICK Computationally mapped isoform of T-cell differentiation antigen CD6 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZHB8-1" }, "locus": { "chromosome": "5", "start_pos": 247094, "end_pos": 244012, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047179.1", "url": "https://www.ensembl.org/id/ENSGALT00010047179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027977.1", "url": "https://www.ensembl.org/id/ENSGALP00010027977.1" } ] } }, { "isoform_ac": "A0A8V0ZHB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB8/entry#A0A8V0ZHB8-1", "sequence": { "sequence": "MGTGIPRHPPPPCPLFVAPVEPTGVPTAVPSNASAEPGENGHPPAGQRARGPPRHPHPELPAGPWDTAVLRLAGGSHPCEGAVQVQHRGLWMPVCRDSWSAAASRELCRRLRCGDAEGDAVAVSPDGDGDAAEGCPTAPANCSGWEPRLCAPVLRLAGGRSRCEGRVELRQAGSWGTVCDDGWDLADAAVVCRQLGCGWALRAPREAAFGRGRGPVLRDEVKCGGHEERLAECPAALQHDCSHKEDAGVVCSEHHEWRLSGGKDGCAGRVEVRYRGTWSTVCDSTWYELEAAVLCRTLGCGEPLQRPSFRHTLPTKMLYECVDLQPSLAYCRWTYNKSAPCHESRAAGVVCNGTAPFGPTRRGLGQRPPPPRVVRLQPSPLSPISSANPSSPPSPSCPVSPAAPPALLVAATPSLSLPADPTPATVPTTKGSDSSDSDYEHYDFSSKPPVALSTFHSENPPFLPSGHLPSMLGSPTDPAPPTPQTPSADSRVSSCCCPARMGWSHFPQRVRQPRPPVPQLPVCPSRGGYMVALCSPSDMHPVFPQCRPRSVPSRGAGRGTHPLPPLPPPWSPTVVRAQPPRVPGPARNPHRAAPTSTQHPPVRGLKRLQGWGRPWGWRWQDPLGGESSGDGSGVGETLRDGDSPRRMWGPQGAAGGPGGAHTAPAFPSTPSRALHAHPSAQHAVGTTTPGRPRPR", "length": 695, "header": "tr|A0A8V0ZHB8-1|A0A8V0ZHB8_CHICK Isoform 1 of T-cell differentiation antigen CD6 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZHB8-1" }, "locus": { "chromosome": "5", "start_pos": 246949, "end_pos": 244012, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047141.1", "url": "https://www.ensembl.org/id/ENSGALT00010047141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027963.1", "url": "https://www.ensembl.org/id/ENSGALP00010027963.1" } ] } }, { "isoform_ac": "A0A8V0ZHD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB8/entry#A0A8V0ZHD5-1", "sequence": { "sequence": "TPPHPTPPHPTPSHPTPSHPAFSVLRLAGGSHPCEGAVQVQHRGLWMPVCRDSWSAAASRELCRRLRCGDAEGDAVAVSPDGDGDAAEGCPTAPANCSGWEPRLCHVTCAPVLRLAGGRSRCEGRVELRQAGSWGTVCDDGWDLADAAVVCRQLGCGWALRAPREAAFGRGRGPVLRDEVKCGGHEERLAECPAALQHDCSHKEDAGVVCSEHHEWRLSGGKDGCAGRVEVRYRGTWSTVCDSTWYELEAAVLCRTLGCGEPLQRPSFRHTLPTKMLYECVDLQPSLAYCRWTYNKSAPCHESRAAGVVCNGTAPFVLSSPISSANPSSPPSPSCPVSPAAPPALLVAATPSLSLPADPTPATVPTTKGSDSSDSDYEHYDFSSKPPVALSTFHSENPPFLPSGHLPSMLGSPTDPAPPTPQTPSADSRVSSCCCPLLPSPAPPAVPCMPTPVLNTPWVPPPPADPDHADSSSTSSGEWYENVQGTEACGDPPLGEHTRDPSFSEGSDYDDIQGSDC", "length": 517, "header": "tr|A0A8V0ZHD5-1|A0A8V0ZHD5_CHICK Computationally mapped isoform of T-cell differentiation antigen CD6 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZHB8-1" }, "locus": { "chromosome": "5", "start_pos": 247094, "end_pos": 243589, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047196.1", "url": "https://www.ensembl.org/id/ENSGALT00010047196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027983.1", "url": "https://www.ensembl.org/id/ENSGALP00010027983.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 422, "start_aa": "Thr", "end_pos": 422, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr422", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 482, "start_aa": "Thr", "end_pos": 482, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr482", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 669, "start_aa": "Thr", "end_pos": 669, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr669", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB8" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 149, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 422, 482, 669 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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24254.0, "monoisotopic_mass": 24254.0 }, "refseq": {}, "gene_names": [ { "name": "ZFAND3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS6" } ] } ], "protein_names": [ { "name": "Zinc finger AN1-type containing 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZFAND3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS6", "locus": { "chromosome": "3", "start_pos": 29355012, "end_pos": 29485080, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021245", "url": "https://www.ensembl.org/id/ENSGALG00010021245" } ] } } ], "crossref": [ { "id": "A0A8V0ZIS6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIS6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHC3", "url": "https://www.orthodb.org/?gene=A0A8V0ZHC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHC6", "url": "https://www.orthodb.org/?gene=A0A8V0ZHC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIS4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIS6", "url": "https://www.orthodb.org/?gene=A0A8V0ZIS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10634", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10634", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10634:SF67", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10634:SF67", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RVPAPAPPWETPAASAARRPACRRAAPAASGDFQKKQPDDDSTPSTSNSQSDLFSGETNSDNSNTSLTTQAANSNQQLLTELNVTSPSKEECGPCTGTAHASLTTPTKRSCDSDSQSESEASPVKRPRLLDDSNDRPEETSRSKQKSRRRCFQCQTKLELVQQELGSCRCGYVFCMLHRLPEQHDCTFDHMGRGREEAIMKMVKLDRKVGRSCQRIGEGCS", "length": 221, "header": "tr|A0A8V0ZIS6-1|A0A8V0ZIS6_CHICK Isoform 1 of Zinc finger AN1-type containing 3 OS=Gallus gallus OX=9031 GN=ZFAND3 PE=4 SV=1 CANONICAL=A0A8V0ZIS6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS6/entry#A0A8V0ZHC3-1", "sequence": { "sequence": "MELAVLRSSKTMNLCSKCFAEKRNPHNEKDFQKKQPDDDSTPSTSNSQSDLFSGETNSDNSNTSLTTQAANSNQQLLTELNVTSPSKEECGPCTGTAHASLTTPTKRSCDSDSQSESEASPVKRPRLLDDSNDRPEETSRSKQKSRRRCFQCQTKLELVQQELGSCRCGYVFCMLHRLPEQHDCTFDHMGRGREEAIMKMVKLDRKVGRSCQRIGEGCS", "length": 219, "header": "tr|A0A8V0ZHC3-1|A0A8V0ZIS6_CHICK Computationally mapped isoform of Zinc finger AN1-type containing 3 OS=Gallus gallus OX=9031 GN=ZFAND3 PE=4 SV=1 CANONICAL=A0A8V0ZIS6-1" }, "locus": { "chromosome": "3", "start_pos": 29459292, "end_pos": 29357490, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051503.1", "url": "https://www.ensembl.org/id/ENSGALT00010051503.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030694.1", "url": "https://www.ensembl.org/id/ENSGALP00010030694.1" } ] } }, { "isoform_ac": "A0A8V0ZHC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS6/entry#A0A8V0ZHC6-1", "sequence": { "sequence": "MGDAGSERSKAPSLPPRCPCGFWGSSKTMNLCSKCFAEKRNPHNEKDFQKKQPDDDSTPSTSNSQSDLFSGETNSDNSNTSLTTQAANSNQQLLTELNVTSPSKEEYSQSESEASPVKRPRLLDDSNDRPEETSRSKQKSRRRCFQCQTKLELVQQELGSCRCGYVFCMLHRLPEQHDCTFDHMGRGREEAIMKMVKLDRKVGRSCQRIGEGCS", "length": 214, "header": "tr|A0A8V0ZHC6-1|A0A8V0ZHC6_CHICK Computationally mapped isoform of Zinc finger AN1-type containing 3 OS=Gallus gallus OX=9031 GN=ZFAND3 PE=4 SV=1 CANONICAL=A0A8V0ZIS6-1" }, "locus": { "chromosome": "3", "start_pos": 29485051, "end_pos": 29357490, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051508.1", "url": "https://www.ensembl.org/id/ENSGALT00010051508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030699.1", "url": "https://www.ensembl.org/id/ENSGALP00010030699.1" } ] } }, { "isoform_ac": "A0A8V0ZIS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS6/entry#A0A8V0ZIS4-1", "sequence": { "sequence": "MLSSKTMNLCSKCFAEKRNPHNEKDFQKKQPDDDSTPSTSNSQSDLFSGETNSDNSNTSLTTQAANSNQQLLTELNVTSPSKEECGPCTGTAHASLTTPTKRSCDSDSQSESEASPVKRPRLLDDSNDRPEETSRSKQKSRRRCFQCQTKLELVQQELGSCRCGYVFCMLHRLPEQHDCTFDHMGRGREEAIMKMVKLDRKVGRSCQRIGEGCS", "length": 214, "header": "tr|A0A8V0ZIS4-1|A0A8V0ZIS4_CHICK Computationally mapped isoform of Zinc finger AN1-type containing 3 OS=Gallus gallus OX=9031 GN=ZFAND3 PE=4 SV=1 CANONICAL=A0A8V0ZIS6-1" }, "locus": { "chromosome": "3", "start_pos": 29453959, "end_pos": 29357490, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051500.1", "url": "https://www.ensembl.org/id/ENSGALT00010051500.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030690.1", "url": "https://www.ensembl.org/id/ENSGALP00010030690.1" } ] } }, { "isoform_ac": "A0A8V0ZIS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS6/entry#A0A8V0ZIS6-1", "sequence": { "sequence": "RVPAPAPPWETPAASAARRPACRRAAPAASGDFQKKQPDDDSTPSTSNSQSDLFSGETNSDNSNTSLTTQAANSNQQLLTELNVTSPSKEECGPCTGTAHASLTTPTKRSCDSDSQSESEASPVKRPRLLDDSNDRPEETSRSKQKSRRRCFQCQTKLELVQQELGSCRCGYVFCMLHRLPEQHDCTFDHMGRGREEAIMKMVKLDRKVGRSCQRIGEGCS", "length": 221, "header": "tr|A0A8V0ZIS6-1|A0A8V0ZIS6_CHICK Isoform 1 of Zinc finger AN1-type containing 3 OS=Gallus gallus OX=9031 GN=ZFAND3 PE=4 SV=1 CANONICAL=A0A8V0ZIS6-1" }, "locus": { "chromosome": "3", "start_pos": 29485074, "end_pos": 29357490, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051505.1", "url": "https://www.ensembl.org/id/ENSGALT00010051505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030696.1", "url": "https://www.ensembl.org/id/ENSGALP00010030696.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc 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"PROSITE", "url": "https://prosite.expasy.org/PS51039" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AN1-type", "eco_id": "ECO_0000259", "start_pos": 145, "end_pos": 194, "start_aa": "Gln", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 64, "end_pos": 66 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZHD2-1", "uniprot_ac": "A0A8V0ZHD2", "uniprot_id": "A0A8V0ZHD2_CHICK", "mass": { "chemical_mass": 337734.0, "monoisotopic_mass": 337734.0 }, "refseq": {}, "gene_names": [ { "name": "EP400", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ] } ], "protein_names": [ { "name": "E1A binding protein p400", "type": "synonym", "evidence": [ { "id": "A0A8V0ZHD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EP400", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2", "locus": { "chromosome": "15", "start_pos": 2598843, "end_pos": 2644601, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022279", "url": "https://www.ensembl.org/id/ENSGALG00010022279" } ] } } ], "crossref": [ { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHD2", "url": "https://www.orthodb.org/?gene=A0A8V0ZHD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ04", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV61", "url": "https://www.orthodb.org/?gene=A0A8V0ZV61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46459", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46459", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46459:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46459:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV61-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHHGNGPQNAQRQLQRSRSFTGSEGEEQQANLPQSPAASFAPSASPSAPQSPSYQIQQFIMSRSPVAGQNVNITLQNVGPVASGNQQITLTPLPIPNPTSPSFQFSPQQRRFEHGSPSYIQVTSPLPQQVQSQSPTQPSPVPVQTLPNVRAGTPGPGLGMCSQSPTRGFVDASVLVRQISLSPSNGGHFVYQEGPGIAQIAQGAAAQVQLPSSGTPATVRERRLSQPHSQSGGTIHHLGPQSPVASGANMQSLTSPGHITTTSLPPQISNIIQGQLMQQQQQVLQGQQLSRPIGYDRASGGLIAGVGGPGAFGMTSPPPPTSPSRATVPQGLSSLPLTPTVNTAVKKQPKKLEEIPPANQETAQMRKQCLDHHHKQMEILKETFKECLIELFFLQHLQGNMMDFLAFKKKHCVPLQAYLRQNDLDLEEEEEEEQSEVINDEQTHTGTPVTGTVNTIEMEAFKRQQTLTPAGGMPPTPQTVQLTGQKQSQQQYDPSKGPPVQNAASLHTPPPQLPGRLQPVNVPMTSLPAALQISQQQPQIVESPTQPQIQVKIQPQSVPLTSAPLPAPLQQQVPPAIHVQGQTPNQVSQPQATIQQQAVTLTRPSADPVQTSQRLTANILPPTSSVAPAAISGTAPPSTYPVQTNRTSPATNKSLSPIASKPPGLAVAAAPKSQSPAQNAAVLPQDNSQDKLAEQVKLENQIHQRIAELRKEGLWSLRRLPKLQEAPRPKSHWDYLLEEMQWMATDFAQERKWKMATAKKMVRTVARYHEEKKLNEERAKREEQNKLRRIAASIAREIEYFWSNIEQVVEIKLQIEFQEKRKKALNLKKISRKGKDAKPSEDLFPIKEGEMGSSSSGRKRKASTSLTDEEVEDEEETIEEQEAKEGNINHQTELSNLVKEAELPLDDLLKMYEGAFSESFHWPQPKPDSEEDSSEEEMDDHMSDRESPQKEVVLIDSLLSIDQYKSIDRSSPPKKHMRDISEVAAAAEVLLPKGSSRITTAVKYNTPSLLYGPLREYQKIGLDWLAKLYRKNLNGILADEAGLGKTVQIIAFFAHLACNEGNWGPHLVVVRSCNILKWELELKRWCPGLKILLYFGSQRELRAKRQEWSEPNSFNVCITSYKQLFKGHPAFMKMRWKYLIVDEMQQIKNMTEKHWEALFSLRSQHRLLLIDTPLHNTLMELWTMVHFLIPGISRPYLDFPVKAPNEENQDYCHKLVIRLHRMIQPFILRRSKRDVEKQLTKKYEHVLKCRLSSRQKAMYEDVILQPGTQEALKSGHFISVLHVLMQLQRICNHPDLINPRLSSTSYVSETLEYRTASLVLSALERDIWKESDLSLFDLIGMENKMTHYEAQMLPKQKVTRKLIEEIYSSPPPPTRPNPVKLKPSRLFQPVQYGQKPEGRTVVFPSTQVQRTVTTATVTQQGQVRGRSPIATVSSNQAAAAQFQTTQASTSAPRHQPAATFTTATSTAHPVKQRGQTAAQASQLGQAQPQPPPHTIQQSVLPQRLVLTSQAQARLPSGEVVKIAQLASIAGAQGRIAQPETPVTLQFQGNKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQQYLRPQGPVVMQTVSQAGTVQNALNALGNQHQAGVPTSTTVTQQVCIPGRTAVTNLSSGDMGAVLKPAPTHGQSQETYEEKNRLLKERLDRIFSGNERRCSRAPVYGSDLLSICLLTGERRPSQVSDSSWRWAGFVNCCLSSASGSPSDPLREMIQTLFREQESLKEVVDRALFVLPAAVAAPPCLYVANPPPSYSHRLKVFKHSLKQKAAPHLHQLRRITTPQLLQFPDLRLVQYDSGKLEALAVLLLKLKSEGRRVLILSQMILMLDILELFLNFHFLTFVRIDEYANHEQRQELMKSFNRDKRIFCAILSSHSRSTGVNLVEADTVVFYDNDLNPVMDAKAQEWCDRIGRCKDIHIYRLVSGNSVEEKLLKNGTKDLIREVAAQGNDYSMAFLTQQTIQELFEVHSPMEDSGFRVKAEEFVVLSQEPSPAETISPKVARPFIEALNSIEREDEELDDRVQEIRPESSIEPLVSELCESKYNEEPSPLQELVAVVDQLTPIEKYALNYLELFHVSVDENEPRLNEVELKTAKKVWEVQHLRELKEKEQKMLWEDEEELLTYTREDAYNKEYVYEGPDGQTEIMPLWTPPTPPQDDNDIYIDSVMCLMYDTTPIPESKLPPVYVRKERKRHKTDPSAAGRKKKQRHGETVIPPRSLFDRATPGMLKMRREGKEQKKNILLKQQTQFAKPLPTLVKPAAETGQDNPEWLISEDWALLQAVKQLLELPLNLAVVSPAHTPNWDLVSDVVNSCSRVYRSPKQCRNRYENVIIPREEGKLMYEANPKKKTKSIYKTKNSRPLRTNQIYAQDEGATHTQLYTNHFEMMKMIAGKRSPPIKPLLGMNPFQKNPKHASVLAESGINYDKPLPPIQVASLRAERIAKEKKALAEQQRAQQQAGPQSQQQQAGQQQAQQPAVQQAQAQPQPQAQAQVVQQPQAVVQTAVTTVANTAVLAGTIKTAVTGTSIQTATVSGNVIVNTVAGVPAATFQPINKRLASPVIPGTLTTSGGTAAAQVVHTQQRAAAAPAASTELVTIASTQGVRAVTSVTASAVVTTNLTPVQTQTRSLVTQVTPATPTVQLSGKTITPAHFQLLRQQQQQAAQVQVPQIQAQAQAQSPAQIKTVGKLSQEQLIKLQKQKLQLPQQQAAQQTQQGAQQQAAQVQVQQQQQTQQLTAVTAPRPGAVLTGTTVTNLQVARLTRVPASQLQAQGQIQAQTPQAAQVALAKPPVVSVPAAVVSSAGVTTLPVTVAGISVAIGQPQKAAGGQTVVAQPLHVQQLLKLKHHQAAQQQKAIQPQVAQGQATVQQKINAQQVTVQAQQQTSQQQKVTYTTQPAIKTQFLTTPISQTQKPGGTQQVQAQIQVAKLPQVVQQQATVANIQQMVSVSQQVQAQPQTVTLSQTTAGQQQVQVIPATTATAQVVQQKLIQQQVVTTASPQIQAPGVQNPAQTPATSEAQNQQAKVQMRTPTVRLKAPTKPS", "length": 3055, "header": "tr|A0A8V0ZHD2-1|A0A8V0ZHD2_CHICK Isoform 1 of E1A binding protein p400 OS=Gallus gallus OX=9031 GN=EP400 PE=4 SV=1 CANONICAL=A0A8V0ZHD2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2/entry#A0A8V0ZHD2-1", "sequence": { "sequence": "MHHGNGPQNAQRQLQRSRSFTGSEGEEQQANLPQSPAASFAPSASPSAPQSPSYQIQQFIMSRSPVAGQNVNITLQNVGPVASGNQQITLTPLPIPNPTSPSFQFSPQQRRFEHGSPSYIQVTSPLPQQVQSQSPTQPSPVPVQTLPNVRAGTPGPGLGMCSQSPTRGFVDASVLVRQISLSPSNGGHFVYQEGPGIAQIAQGAAAQVQLPSSGTPATVRERRLSQPHSQSGGTIHHLGPQSPVASGANMQSLTSPGHITTTSLPPQISNIIQGQLMQQQQQVLQGQQLSRPIGYDRASGGLIAGVGGPGAFGMTSPPPPTSPSRATVPQGLSSLPLTPTVNTAVKKQPKKLEEIPPANQETAQMRKQCLDHHHKQMEILKETFKECLIELFFLQHLQGNMMDFLAFKKKHCVPLQAYLRQNDLDLEEEEEEEQSEVINDEQTHTGTPVTGTVNTIEMEAFKRQQTLTPAGGMPPTPQTVQLTGQKQSQQQYDPSKGPPVQNAASLHTPPPQLPGRLQPVNVPMTSLPAALQISQQQPQIVESPTQPQIQVKIQPQSVPLTSAPLPAPLQQQVPPAIHVQGQTPNQVSQPQATIQQQAVTLTRPSADPVQTSQRLTANILPPTSSVAPAAISGTAPPSTYPVQTNRTSPATNKSLSPIASKPPGLAVAAAPKSQSPAQNAAVLPQDNSQDKLAEQVKLENQIHQRIAELRKEGLWSLRRLPKLQEAPRPKSHWDYLLEEMQWMATDFAQERKWKMATAKKMVRTVARYHEEKKLNEERAKREEQNKLRRIAASIAREIEYFWSNIEQVVEIKLQIEFQEKRKKALNLKKISRKGKDAKPSEDLFPIKEGEMGSSSSGRKRKASTSLTDEEVEDEEETIEEQEAKEGNINHQTELSNLVKEAELPLDDLLKMYEGAFSESFHWPQPKPDSEEDSSEEEMDDHMSDRESPQKEVVLIDSLLSIDQYKSIDRSSPPKKHMRDISEVAAAAEVLLPKGSSRITTAVKYNTPSLLYGPLREYQKIGLDWLAKLYRKNLNGILADEAGLGKTVQIIAFFAHLACNEGNWGPHLVVVRSCNILKWELELKRWCPGLKILLYFGSQRELRAKRQEWSEPNSFNVCITSYKQLFKGHPAFMKMRWKYLIVDEMQQIKNMTEKHWEALFSLRSQHRLLLIDTPLHNTLMELWTMVHFLIPGISRPYLDFPVKAPNEENQDYCHKLVIRLHRMIQPFILRRSKRDVEKQLTKKYEHVLKCRLSSRQKAMYEDVILQPGTQEALKSGHFISVLHVLMQLQRICNHPDLINPRLSSTSYVSETLEYRTASLVLSALERDIWKESDLSLFDLIGMENKMTHYEAQMLPKQKVTRKLIEEIYSSPPPPTRPNPVKLKPSRLFQPVQYGQKPEGRTVVFPSTQVQRTVTTATVTQQGQVRGRSPIATVSSNQAAAAQFQTTQASTSAPRHQPAATFTTATSTAHPVKQRGQTAAQASQLGQAQPQPPPHTIQQSVLPQRLVLTSQAQARLPSGEVVKIAQLASIAGAQGRIAQPETPVTLQFQGNKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQQYLRPQGPVVMQTVSQAGTVQNALNALGNQHQAGVPTSTTVTQQVCIPGRTAVTNLSSGDMGAVLKPAPTHGQSQETYEEKNRLLKERLDRIFSGNERRCSRAPVYGSDLLSICLLTGERRPSQVSDSSWRWAGFVNCCLSSASGSPSDPLREMIQTLFREQESLKEVVDRALFVLPAAVAAPPCLYVANPPPSYSHRLKVFKHSLKQKAAPHLHQLRRITTPQLLQFPDLRLVQYDSGKLEALAVLLLKLKSEGRRVLILSQMILMLDILELFLNFHFLTFVRIDEYANHEQRQELMKSFNRDKRIFCAILSSHSRSTGVNLVEADTVVFYDNDLNPVMDAKAQEWCDRIGRCKDIHIYRLVSGNSVEEKLLKNGTKDLIREVAAQGNDYSMAFLTQQTIQELFEVHSPMEDSGFRVKAEEFVVLSQEPSPAETISPKVARPFIEALNSIEREDEELDDRVQEIRPESSIEPLVSELCESKYNEEPSPLQELVAVVDQLTPIEKYALNYLELFHVSVDENEPRLNEVELKTAKKVWEVQHLRELKEKEQKMLWEDEEELLTYTREDAYNKEYVYEGPDGQTEIMPLWTPPTPPQDDNDIYIDSVMCLMYDTTPIPESKLPPVYVRKERKRHKTDPSAAGRKKKQRHGETVIPPRSLFDRATPGMLKMRREGKEQKKNILLKQQTQFAKPLPTLVKPAAETGQDNPEWLISEDWALLQAVKQLLELPLNLAVVSPAHTPNWDLVSDVVNSCSRVYRSPKQCRNRYENVIIPREEGKLMYEANPKKKTKSIYKTKNSRPLRTNQIYAQDEGATHTQLYTNHFEMMKMIAGKRSPPIKPLLGMNPFQKNPKHASVLAESGINYDKPLPPIQVASLRAERIAKEKKALAEQQRAQQQAGPQSQQQQAGQQQAQQPAVQQAQAQPQPQAQAQVVQQPQAVVQTAVTTVANTAVLAGTIKTAVTGTSIQTATVSGNVIVNTVAGVPAATFQPINKRLASPVIPGTLTTSGGTAAAQVVHTQQRAAAAPAASTELVTIASTQGVRAVTSVTASAVVTTNLTPVQTQTRSLVTQVTPATPTVQLSGKTITPAHFQLLRQQQQQAAQVQVPQIQAQAQAQSPAQIKTVGKLSQEQLIKLQKQKLQLPQQQAAQQTQQGAQQQAAQVQVQQQQQTQQLTAVTAPRPGAVLTGTTVTNLQVARLTRVPASQLQAQGQIQAQTPQAAQVALAKPPVVSVPAAVVSSAGVTTLPVTVAGISVAIGQPQKAAGGQTVVAQPLHVQQLLKLKHHQAAQQQKAIQPQVAQGQATVQQKINAQQVTVQAQQQTSQQQKVTYTTQPAIKTQFLTTPISQTQKPGGTQQVQAQIQVAKLPQVVQQQATVANIQQMVSVSQQVQAQPQTVTLSQTTAGQQQVQVIPATTATAQVVQQKLIQQQVVTTASPQIQAPGVQNPAQTPATSEAQNQQAKVQMRTPTVRLKAPTKPS", "length": 3055, "header": "tr|A0A8V0ZHD2-1|A0A8V0ZHD2_CHICK Isoform 1 of E1A binding protein p400 OS=Gallus gallus OX=9031 GN=EP400 PE=4 SV=1 CANONICAL=A0A8V0ZHD2-1" }, "locus": { "chromosome": "15", "start_pos": 2642971, "end_pos": 2599601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054220.1", "url": "https://www.ensembl.org/id/ENSGALT00010054220.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032730.1", "url": "https://www.ensembl.org/id/ENSGALP00010032730.1" } ] } }, { "isoform_ac": "A0A8V0ZQ04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2/entry#A0A8V0ZQ04-1", "sequence": { "sequence": "MHHGNGPQNAQRQLQRSRSFTGSEGEEQQANLPQSPAASFAPSASPSAPQSPSYQIQQFIMSRSPVAGQNVNITLQNVGPVASGNQQITLTPLPIPNPTSPSFQFSPQQRRFEHGSPSYIQVTSPLPQQVQSQSPTQPSPVPVQTLPNVRAGTPGPGLGMCSQSPTRGFVDASVLVRQISLSPSNGGHFVYQEGPGIAQIAQGAAAQVQLPSSGTPATVRERRLSQPHSQSGGTIHHLGPQSPVASGANMQSLTSPGHITTTSLPPQISNIIQGQLMQQQQQVLQGQQLSRPIGYDRASGGLIAGVGGPGAFGMTSPPPPTSPSRATVPQGLSSLPLTPTVNTAVKKQPKKLEEIPPANQETAQMRKQCLDHHHKQMEILKETFKECLIELFFLQHLQGNMMDFLAFKKKHCVPLQAYLRQNDLDLEEEEEEEQSEVINDEQTHTGTPVTGTVNTIEMEAFKRQQTLTPAGGMPPTPQTVQLTGQKQSQQQYDPSKGPPVQNAASLHTPPPQLPGRLQPVNVPMTSLPAALQISQQQPQIVESPTQPQIQVKIQPQSVPLTSAPLPAPLQQQVPPAIHVQGQTPNQVSQPQATIQQQAVTLTRPSADPVQTSQRLTANILPPTSSVAPAAISGTAPPSTYPVQTNRTSPATNKSLSPIASKPPGLAVAAAPKSQSPAQNAAVLPQDNSQDKLAEQVKLENQIHQRIAELRKEGLWSLRRLPKLQEAPRPKSHWDYLLEEMQWMATDFAQERKWKMATAKKMVRTVARYHEEKKLNEERAKREEQNKLRRIAASIAREIEYFWSNIEQVVEIKLQIEFQEKRKKALNLKKISRKGKDAKPSEDLFPIKEGEMGSSSSGRKRKASTSLTDEEVEDEEETIEEQEAKEGNINHQTELSNLVKEAELPLDDLLKMYEGAFSESFHWPQPKPDSEEDSSEEEMDDHMSDRESPQKEVVLIDSLLSIDQYKSIDRSSPPKKHMRDISEVAAAAEVLLPKGSSRITTAVKYNTPSLLYGPLREYQKIGLDWLAKLYRKNLNGILADEAGLGKTVQIIAFFAHLACNEGNWGPHLVVVRSCNILKWELELKRWCPGLKILLYFGSQRELRAKRQEWSEPNSFNVCITSYKQLFKGHPAFMKMRWKYLIVDEMQQIKNMTEKHWEALFSLRSQHRLLLIDTPLHNTLMELWTMVHFLIPGISRPYLDFPVKAPNEENQDYCHKLVIRLHRMIQPFILRRSKRDVEKQLTKKYEHVLKCRLSSRQKAMYEDVILQPGTQEALKSGHFISVLHVLMQLQRICNHPDLINPRLSSTSYVSETLEYRTASLVLSALERDIWKESDLSLFDLIGMENKMTHYEAQMLPKQKVTRKLIEEIYSSPPPPTRPNPVKLKPSRLFQPVQYGQKPEGRTVVFPSTQVQRTVTTATVTQQGQVRGRSPIATVSSNQAAAAQFQTTQASTSAPRHQPAATFTTATSTAHPVKQRGQTAAQASQLGQAQPQPPPHTIQQSVLPQRLVLTSQAQARLPSGEVVKIAQLASIAGAQGRIAQPETPVTLQFQGNKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQQYLRPQGPVVMQTVSQAGTVQNALNALGNQHQAGVPTSTTVTQQVCIPGRTAVTNLSSGDMGAVLKPAPTHGQSQETYEEKNRLLKERLDRIFSGNERRCSRAPVYGSDLLSICLLTGERRPSQVSDSSWRWAGFVNCCLSSASGSPSDPLREMIQTLFREQESLKEVVDRALFVLPAAVAAPPCLYVANPPPSYSHRLKVFKHSLKQKAAPHLHQLRRITTPQLLQFPDLRLVQYDSGKLEALAVLLLKLKSEGRRVLILSQMILMLDILELFLNFHFLTFVRIDEYANHEQRQELMKSFNRDKRIFCAILSSHSRSTGVNLVEADTVVFYDNDLNPVMDAKAQEWCDRIGRCKDIHIYRLVSGNSVEEKLLKNGTKDLIREVAAQGNDYSMAFLTQQTIQELFEVHSPMEDSGFRVKAEEFVVLSQEPSPAETISPKVARPFIEALNSIEREDEELDDRVQEIRPESSIEPLVSELCESKYNEEPSPLQELVAVVDQLTPIEKYALNYLELFHVSVDENEPRLNEVELKTAKKVWEVQHLRELKEKEQKMLWEDEEELLTYTREDAYNKEYVYEGPDGQTEIMPLWTPPTPPQDDNDIYIDSVMCLMYDTTPIPESKLPPVYVRKERKRHKTDPSAAGRKKKQRHGETVIPPRSLFDRATPGMLKMRREGKEQKKNILLKQQTQFAKPLPTLVKPAAETGQDNPEWLISEDWALLQAVKQLLELPLNLAVVSPAHTPNWDLVSDVVNSCSRVYRSPKQCRNRYENVIIPREEGKTKNSRPLRTNQIYAQDEGATHTQLYTNHFEMMKMIAGKRSPPIKPLLGMNPFQKNPKHASVLAESGINYDKPLPPIQVASLRAERIAKEKKALAEQQRAQQQAGPQSQQQQAGQQQAQQPAVQQAQAQPQPQAQAQVVQQPQAVVQTAVTTVANTAVLAGTIKTAVTGTSIQTATVSGNVIVNTVAGVPAATFQPINKRLASPVIPGTLTTSGGTAAAQVVHTQQRAAAAPAASTELVTIASTQGVRAVTSVTASAVVTTNLTPVQTQTRSLVTQVTPATPTVQLSGKTITPAHFQLLRQQQQQAAQVQVPQIQAQAQAQSPAQIKTVGKLSQEQLIKLQKQKLQLPQQQAAQQTQQGAQQQAAQVQVQQQQQTQQLTAVTAPRPGAVLTGTTVTNLQVARLTRVPASQLQAQGQIQAQTPQAAQVALAKPPVVSVPAAVVSSAGVTTLPVTVAGISVAIGQPQKAAGGQTVVAQPLHVQQLLKLKHHQAAQQQKAIQPQVAQGQATVQQKINAQQVTVQAQQQTSQQQKVTYTTQPAIKTQFLTTPISQTQKPGGTQQVQAQIQVAKLPQVVQQQATVANIQQMVSVSQQVQAQPQTVTLSQTTAGQQQVQVIPATTATAQVVQQKLIQQQVVTTASPQIQAPGVQNPAQTPATSEAQNQQAKVQMRTPTVRLKAPTKPS", "length": 3039, "header": "tr|A0A8V0ZQ04-1|A0A8V0ZQ04_CHICK Computationally mapped isoform of E1A binding protein p400 OS=Gallus gallus OX=9031 GN=EP400 PE=4 SV=1 CANONICAL=A0A8V0ZHD2-1" }, "locus": { "chromosome": "15", "start_pos": 2642971, "end_pos": 2599601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054230.1", "url": "https://www.ensembl.org/id/ENSGALT00010054230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032738.1", "url": "https://www.ensembl.org/id/ENSGALP00010032738.1" } ] } }, { "isoform_ac": "A0A8V0ZV61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2/entry#A0A8V0ZV61-1", "sequence": { "sequence": 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"length": 3049, "header": "tr|A0A8V0ZV61-1|A0A8V0ZHD2_CHICK Computationally mapped isoform of E1A binding protein p400 OS=Gallus gallus OX=9031 GN=EP400 PE=4 SV=1 CANONICAL=A0A8V0ZHD2-1" }, "locus": { "chromosome": "15", "start_pos": 2642971, "end_pos": 2599601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054236.1", "url": "https://www.ensembl.org/id/ENSGALT00010054236.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032741.1", "url": "https://www.ensembl.org/id/ENSGALP00010032741.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 215, "start_aa": "Thr", "end_pos": 215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2174, "start_aa": "Thr", "end_pos": 2174, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2174", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2651, "start_aa": "Thr", "end_pos": 2651, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2651", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 321, "start_aa": "Thr", "end_pos": 321, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr321", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 476, "start_aa": "Thr", "end_pos": 476, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr476", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" }, { "name": "Swr1 complex", "id": "GO:0000812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000812", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1149, "end_pos": 1151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1637, "end_pos": 1639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1957, "end_pos": 1959, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2635, "end_pos": 2637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZHD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD2" }, { "id": "PS51204", 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The reference sequence was derived from JAENSK010000236.1. 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McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T", "evidence": [ { "database": "Reactome", "id": "R-GGA-1227882", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227882" } ], "reference": [ { "type": "PubMed", "id": "12692549", "url": "https://glygen.org/publication/PubMed/12692549" } ] }, { "title": "X-ray crystal structure of IRF-3 and its functional implications.", "journal": "Nature structural biology", "date": "2003", "authors": "Takahasi K, Suzuki NN, Horiuchi M, Mori M, Suhara W, Okabe Y, Fukuhara Y, Terasawa H, Akira S, Fujita T, Inagaki F", "evidence": [ { "database": "Reactome", "id": "R-GGA-1227882", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227882" } ], "reference": [ { "type": "PubMed", "id": "14555995", "url": "https://glygen.org/publication/PubMed/14555995" } ] }, { "title": "VISA is an adapter protein required for virus-triggered IFN-beta signaling.", "journal": "Molecular cell", "date": "2005", "authors": "Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB", "evidence": [ { "database": "Reactome", "id": "R-GGA-1227882", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227882" } ], "reference": [ { "type": "PubMed", "id": "16153868", "url": "https://glygen.org/publication/PubMed/16153868" } ] }, { "title": "Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif.", "journal": "The EMBO journal", "date": "2006", "authors": "Saha SK, Pietras EM, He JQ, Kang JR, Liu SY, Oganesyan G, Shahangian A, Zarnegar B, Shiba TL, Wang Y, Cheng G", "evidence": [ { "database": "Reactome", "id": "R-GGA-1227882", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227882" } ], "reference": [ { "type": "PubMed", "id": "16858409", "url": "https://glygen.org/publication/PubMed/16858409" } ] }, { "title": "Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway.", "journal": "Cellular and molecular biology (Noisy-le-Grand, France)", "date": "2006", "authors": "Paz S, Sun Q, Nakhaei P, Romieu-Mourez R, Goubau D, Julkunen I, Lin R, Hiscott J", "evidence": [ { "database": "Reactome", "id": "R-GGA-1227882", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227882" } ], "reference": [ { "type": "PubMed", "id": "16914100", "url": "https://glygen.org/publication/PubMed/16914100" } ] }, { "title": "Regulation and function of IKK and IKK-related kinases.", "journal": "Science's STKE : signal transduction knowledge environment", "date": "2006", "authors": "Hacker H, Karin M", "evidence": [ { "database": "Reactome", "id": "R-GGA-1227882", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227882" } ], "reference": [ { "type": "PubMed", "id": "17047224", "url": "https://glygen.org/publication/PubMed/17047224" } ] }, { "title": "Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Lamothe B, Besse A, Campos AD, Webster WK, Wu H, Darnay BG", "evidence": [ { "database": "Reactome", "id": "R-GGA-1227882", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227882" } ], "reference": [ { "type": "PubMed", "id": "17135271", "url": "https://glygen.org/publication/PubMed/17135271" } ] }, { "title": "Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Guo B, Cheng G", "evidence": [ { "database": "Reactome", "id": "R-GGA-1227882", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227882" } ], "reference": [ { "type": "PubMed", "id": "17327220", "url": "https://glygen.org/publication/PubMed/17327220" } ] }, { "title": "Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity.", "journal": "Science (New York, N.Y.)", "date": "2007", "authors": "Tenoever BR, Ng SL, Chua MA, McWhirter SM, Garcia-Sastre A, Maniatis T", "evidence": [ { "database": "Reactome", "id": "R-GGA-1227882", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227882" } ], "reference": [ { "type": "PubMed", "id": "17332413", "url": "https://glygen.org/publication/PubMed/17332413" } ] }, { "title": "Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Panne D, McWhirter SM, Maniatis T, Harrison SC", "evidence": [ { "database": "Reactome", "id": "R-GGA-1227882", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1227882" } ], "reference": [ { "type": "PubMed", "id": "17526488", "url": "https://glygen.org/publication/PubMed/17526488" } ] }, { "title": "E2 interaction and dimerization in the crystal structure of TRAF6.", "journal": "Nature structural & molecular biology", "date": "2009", "authors": "Yin Q, Lin SC, Lamothe B, Lu M, Lo YC, Hura G, Zheng L, Rich RL, 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This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149850.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149850" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF216", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU7", "locus": { "chromosome": "14", "start_pos": 4206431, "end_pos": 4268344, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021251", "url": "https://www.ensembl.org/id/ENSGALG00010021251" } ] } } ], "crossref": [ { "id": "A0A8V0ZIU7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIU7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16630", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16630", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20339", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20339", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20353", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20353", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416486", "url": "https://www.ncbi.nlm.nih.gov/gene/416486", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047544", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047544", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047545", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047545", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051628", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051628", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416486", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416486", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WINHRDE", "url": "https://omabrowser.org/oma/group/WINHRDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHE6", "url": "https://www.orthodb.org/?gene=A0A8V0ZHE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIU7", "url": "https://www.orthodb.org/?gene=A0A8V0ZIU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPQ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZPQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22770", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22770", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22770:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22770:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26112", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26112", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26200", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26200", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28408", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28408", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28565", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28565", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149850", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAERAGNEEAVHLSSFHSHRGKDRINRRDEGLITISDSSDEELPLQETPAEQQHEDDDDEDVVILAETSKHQQLVRPNIIRPAAQWQGANAVGEGGSKNAVGPLGSACVQDEVSALLGQKDHTVQSSAGPSKEESVNFALQQPGPPELNGPRSELTSDPEPGPSLFPAIKTSAQLVNRDLVSLGKADFPPPQGEKVEAQGWRGEDWKAELSQNVEGAAAATTNTEQEIQDSSPPGPPCLQPLDEEPRAVLNGCVPQQGQPEAGSASLRAYGEEAPGPAFPRPEPQQDGIPGPASPQPAHPPEETRGRQATDNEQPGPAFPAQGSHELGSSSVPEQGAAGQEDQDFTALLIRETEARFPDVRKEYIEELISIKDCYDLNVLCNFLLENPDYPKKEGRMVLNPSSSLLASQDETKVPKVDYFDFSKLAPLDQRCFIQAADLLMADFKMLSSQDIKWALHELKGHYAITRKAFSDAIKKWQELSPETSGKRKRRKEMNQYSYIDFKFEQGDVKIEKRMFFLENKRRHWRSYDKLSLLPPVLLEQEFYEQKVKEMAEHADFLLALQMNEEQYQKDGQMIECRCCYGEFAFEELTQCADGHLFCKECLIKYAQEAVFGSGKSELSCMEGSCTCSFPTSELEKVLPETILCKYYERKAEEEVAAACADELVRCPFCNFPALLDNDVKRFSCPNPRCRKETCRKCQGLWKEHMNLTCEQLAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRAAINGYDHFCQHPRSPGAPCQDCAKCSLWTDPTEDDEKIIQEIQKEAEEEQRKKNGENSFKRIGPPVEKPMEKMQRIEVIPRPVPQNLHQPRMPPYPFVHPPFPLPPVRPMYNNIPLNIGPIPAPYVPPLPNMRVNYDFPQINVQLEHNLPMHFGPQPRHRF", "length": 928, "header": "tr|A0A8V0ZIU7-1|A0A8V0ZIU7_CHICK Isoform 1 of E3 ubiquitin-protein ligase RNF216 OS=Gallus gallus OX=9031 GN=RNF216 PE=4 SV=1 CANONICAL=A0A8V0ZIU7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU7/entry#A0A8V0ZHE6-1", "sequence": { "sequence": "MAERAGNEEAVHLSSFHSHRGKDRINRRDEGLITISDSSDEELPLQETPAEQQHEDDDDEDVVILAETSKHQQLVRPNIIRPAAQWQGANAVGEGGSKNAVGPLGSACVQDEVSALLGQKDHTVQSSAGPSKEESVNFALQQPGPPELNGPRSELTSDPEPGPSLFPAIKTSAQLVNRDLVSLGKADFPPPQGEKVEAQGWRGEDWKAELSQNVEGAAAATTNTEQEIQDSSPPGPPCLQPLDEEPRAVLNGCVPQQGQPEAGSASLRAYGEEAPGPAFPRPEPQQDGIPGPASPQPAHPPEETRGRQATDNEQPGPAFPAQGSHELGSSSVPEQGAAGQEDQDFTALLIRETEARFPDVRKEYIEELISIKDCYDLNVLCNFLLENPDYPKKEGRMVLNPSSSLLASQDETKVPKVDYFDFSKLAPLDQRCFIQAADLLMADFKMLSSQDIKWALHELKGHYAITRKAFSDAIKKWQELSPETSGKRKRRKEMNQYSYIDFKFEQGDVKIEKRMFFLENKRRHWRSYDKLSLLPPVLLEQEFYEQKVKEMAEHADFLLALQMNEEQYQKDGQMIECRCCYGEFAFEELTQCADGHLFCKECLIKYAQEAVFGSGKSELSCMEGSCTCSFPTSELEKVLPETILCKYYERKAEEEVAAACADELVRCPFCNFPALLDNDVKRFSCPNPRCRKETCRKCQGLWKEHMNLTCEQLAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRAAINGYDHFCQHPRSPGAPCQDCAKCSLWTDPTEDDEKIIQEIQKEAEEEQRKKNGEQLQADRPSGGKAHGENAENRSHPQTCSSEPPSATDASLPLRAPSLPAAPRPSHVQ", "length": 878, "header": "tr|A0A8V0ZHE6-1|A0A8V0ZIU7_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase RNF216 OS=Gallus gallus OX=9031 GN=RNF216 PE=4 SV=1 CANONICAL=A0A8V0ZIU7-1" }, "locus": { "chromosome": "14", "start_pos": 4260163, "end_pos": 4207128, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051528.1", "url": "https://www.ensembl.org/id/ENSGALT00010051528.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030719.1", "url": "https://www.ensembl.org/id/ENSGALP00010030719.1" } ] } }, { "isoform_ac": "A0A8V0ZIU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU7/entry#A0A8V0ZIU7-1", "sequence": { "sequence": "MAERAGNEEAVHLSSFHSHRGKDRINRRDEGLITISDSSDEELPLQETPAEQQHEDDDDEDVVILAETSKHQQLVRPNIIRPAAQWQGANAVGEGGSKNAVGPLGSACVQDEVSALLGQKDHTVQSSAGPSKEESVNFALQQPGPPELNGPRSELTSDPEPGPSLFPAIKTSAQLVNRDLVSLGKADFPPPQGEKVEAQGWRGEDWKAELSQNVEGAAAATTNTEQEIQDSSPPGPPCLQPLDEEPRAVLNGCVPQQGQPEAGSASLRAYGEEAPGPAFPRPEPQQDGIPGPASPQPAHPPEETRGRQATDNEQPGPAFPAQGSHELGSSSVPEQGAAGQEDQDFTALLIRETEARFPDVRKEYIEELISIKDCYDLNVLCNFLLENPDYPKKEGRMVLNPSSSLLASQDETKVPKVDYFDFSKLAPLDQRCFIQAADLLMADFKMLSSQDIKWALHELKGHYAITRKAFSDAIKKWQELSPETSGKRKRRKEMNQYSYIDFKFEQGDVKIEKRMFFLENKRRHWRSYDKLSLLPPVLLEQEFYEQKVKEMAEHADFLLALQMNEEQYQKDGQMIECRCCYGEFAFEELTQCADGHLFCKECLIKYAQEAVFGSGKSELSCMEGSCTCSFPTSELEKVLPETILCKYYERKAEEEVAAACADELVRCPFCNFPALLDNDVKRFSCPNPRCRKETCRKCQGLWKEHMNLTCEQLAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRAAINGYDHFCQHPRSPGAPCQDCAKCSLWTDPTEDDEKIIQEIQKEAEEEQRKKNGENSFKRIGPPVEKPMEKMQRIEVIPRPVPQNLHQPRMPPYPFVHPPFPLPPVRPMYNNIPLNIGPIPAPYVPPLPNMRVNYDFPQINVQLEHNLPMHFGPQPRHRF", "length": 928, "header": "tr|A0A8V0ZIU7-1|A0A8V0ZIU7_CHICK Isoform 1 of E3 ubiquitin-protein ligase RNF216 OS=Gallus gallus OX=9031 GN=RNF216 PE=4 SV=1 CANONICAL=A0A8V0ZIU7-1" }, "locus": { "chromosome": "14", "start_pos": 4260163, "end_pos": 4206980, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051525.1", "url": "https://www.ensembl.org/id/ENSGALT00010051525.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030716.1", "url": "https://www.ensembl.org/id/ENSGALP00010030716.1" } ] } }, { "isoform_ac": "A0A8V0ZPQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIU7/entry#A0A8V0ZPQ8-1", "sequence": { "sequence": "MAERAGNEEAVHLSSFHSHRGKDRINRRDEGLITISDSSDEELPLQETPAEQQHEDDDDEDVVILAETSKHQQLVRPNIIRPAAQWQGANAVGEGGSKNAVGPLGSACVQDEVSALLGQKDHTVQSSAGPSKEESVNFALQQPGPPELNGPRSELTSDPEPGPSLFPAIKTSAQLVNRDLVSLGKADFPPPQGEKVEAQGWRGEDWKAELSQNVEGAAAATTNTEQEIQDSSPPGPPCLQPLDEEPRAVLNGCVPQQGQPEAGSASLRAYGEEAPGPAFPRPEPQQDGIPGPASPQPAHPPEETRGRQATDNEQPGPAFPAQGSHELGSSSVPEQGAAGQEDQDFTALLIRETEARFPDVRKEYIEELISIKDCYDLNVLCNFLLENPDYPKKEGRMVLNPSSSLLASQDETKVPKVDYFDFSKLAPLDQRCFIQAADLLMADFKMLSSQDIKWALHELKGHYAITRKAFSDAIKKWQELSPETSGKRKRRKEMNQYSYIDFKFEQGDVKIEKRMFFLENKRRHWRSYDKLSLLPPVLLEQEFYEQKVKEMAEHADFLLALQMNEEQYQKDGQMIECRCCYGEFAFEELTQCADGHLFCKECLIKYAQEAVFGSGKSELSCMEGSCTCSFPTSELEKVLPETILCKYYERKAEEEVAAACADELVRCPFCNFPALLDNDVKRFSCPNPRCRKETCRKCQGLWKEHMNLTCEQLAEKDDIKYRTSMKEGGEGGETSCRVPDMNKNQFQNLWQIVAADREEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRAAINGYDHFCQHPRSPGAPCQDCAKCSLWTDPTEDDEKIIQEIQKEAEEEQRKKNGENSFKRIGPPVEKPMEKMQRIEVIPRPVPQNLHQPRMPPYPFVHPPFPLPPVRPMYNNIPLNIGPIPAPYVPPLPNMRVNYDFPQINVQLEHNLPMHFGPQPRHRF", "length": 960, "header": "tr|A0A8V0ZPQ8-1|A0A8V0ZPQ8_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase RNF216 OS=Gallus gallus OX=9031 GN=RNF216 PE=4 SV=1 CANONICAL=A0A8V0ZIU7-1" }, "locus": { "chromosome": "14", "start_pos": 4260163, "end_pos": 4206980, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051522.1", "url": "https://www.ensembl.org/id/ENSGALT00010051522.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030713.1", "url": "https://www.ensembl.org/id/ENSGALP00010030713.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416486", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416486", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LQ03-1", "protein_name": "E3 ubiquitin-protein ligase RNF216", "gene_name": "Rnf216", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEGNNKEEVIHLNNFHCHRGEEWMSVRDGTITISDSSDEEGIPMLVTPATEQHEDDDLDDDVILTEKHKPQTSRPNLIKPAAQWQDLNRLGEERPRKSRADCEAETHSSFSFCNNSLFGSGEQDDSEDEYGEFLDLESGTKGEAKPGPSNKQTANNTVNPNLDQKVLILGENDLLFPESEPLEAQNQSYEDSETDLLSNPGEPATSVDDQVIEEEYWLDHPYFQALNPQPQERTNQVVPQERHSEAEMGPLFLRHDFPEPAFPRPEPQQEGIPGPASPQLAHPLGELEDQQLAIDEDPGPAFPLPGSQQANLENMWGQEAAQVDQELVTLLVKETEARFPDVAKGYVKEIIHLKNYYDLNVLCNFLLENPDYPKREDRIIIHPSSSLLASQDDMKLPKVDFFDYSKLTPLDQRCFIQAADLLMADFKMLSSQDIKWALHELKGHYAITRKAFSDAIKKWQELSPEASGKRKKRKEMNQYSFIDFKFEQGNIKIEKRMFFLENKRRHCRSYDQQALLPAVQQEQEFYDQKVKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGAGKSELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVTAAYADELVRCPSCSFPALLDSDVKRFSCPNPRCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPAEKVQRVEALPRPVPQNLHPHMPPYAFVHPPFPLAPVRPVFNNFPINIGPVPAPYVPPLPNVRVNYDFGHVHVPLEHNLPMHFGPQPRHRF", "length": 910 }, "evidence": [ { "id": "A0A8V0ZIU7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIU7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0L925-1", "protein_name": "E3 ubiquitin-protein ligase RNF216", "gene_name": "Rnf216", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEGNNQEEVIHLNNFHCHRGKEWMAVREGPITISDSSDEEGIPMLVTPATEQQEDDLDDDVILTETHKPQTSRPNLIKPAAEWQDLNRLGEERPRKSRADFEADTHSYFSFCNNSLFDSGAQDDSEDECGGFLDLKTEKKGGEAKPGPSNKQTADNTVSPRLEQKVIILGENGLLFSESEPLEVQNQLSEDSETDLLSNPGEPAASVDEQLIEEEYWLDHPYFQALNPQPQERTNQLVPQERHSESEMGPMFFRHDFPEPAFPRPEPQQEGIPGPASPQPAHPLGELEDQQLAIDEDPGPAYPLPGPQEANLANVWGQEAAEGDQELIPLLVKETEARFPDVANGYVEEIIHLKNYYDLNVLCNFLLENPDYPKREDRILIHPSSSLLASQDDVKLPKIDFFDYSKLTPLDQRCFIQAADLLMADFKMLSSQDIKWALHELKGHYAITRKAFSDAIKKWQELSPETSGKRKKRKEMNQYSFIDFKFEQGNIKIEKRMFFLENKRRHCRSYDQQALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKSELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPRCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPAEKVQRVEALPRPVPQNLHPQMPPYAFVHPPFPLPPVRPVFNNFPINMGPVPAPYVPPLPNVRVNFDFGHVHVPLEHNLPMHFGPQPRHRF", "length": 910 }, "evidence": [ { "id": "A0A8V0ZIU7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIU7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P58283-1", "protein_name": "E3 ubiquitin-protein ligase RNF216", "gene_name": "Rnf216", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEGNNKEEVIHLNNFPCHRGKEWMAVREGPITISDSSDEEGIPMLVTPATEQQEDDLDDDVILTEDDSEDEYGGFLDLESGKKEGEAKPGPSSKQTADDIVNPRLEQKVIILGENGLLFPESEPLEVQNQSSEDSETELLSNPGEPAASVDDQLIGEEYWLDHPYFQAPNPQPQERTNQVVPQERHSESEMGPMFFRHDFPEPAFPRPEPQQEGIPGPASPQPAHPLGELEDQQLAIDEDPGPAFPLSGPQEANLANMWEQEAAEVDQDLIPLLVKETEARFPDVASGYVEEIIHLKNYYDLNVLCNFLLENPDYPKREDRLIIHPSSSLLASQDDAKLPKIDFFDYSKLTPLDQRCFIQAADLLMADFKMLSSQDIKWALHELKGHYAITRKAFSDAIKKWQELSPETSGKRKKRKEMNQYSFIDFKFEQGNIKIEKRMFFLENKRRHCRYYDHQALLPAVKQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKSELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPRCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPAEKVQRVEALPRPVPQNLHPQMPPYAFVHPPFPLPPVRPVFNNFPINMGPVPAPYVPPLPNVRVNYDFGHMHVPLEHNLPMHFGPQPRHRF", "length": 853 }, "evidence": [ { "id": "A0A8V0ZIU7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIU7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWF9-2", "protein_name": "E3 ubiquitin-protein ligase RNF216", "gene_name": "RNF216", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLDDDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQQPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFEDQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFIEEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDFGPIHMPLEHNLPMHFGPQPRHRF", "length": 866 }, "evidence": [ { "id": "A0A8V0ZIU7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIU7/", "database": "OMA" } ], 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZHG1-1", "uniprot_ac": "A0A8V0ZHG1", "uniprot_id": "A0A8V0ZHG1_CHICK", "mass": { "chemical_mass": 42847.0, "monoisotopic_mass": 42847.0 }, "refseq": { "ac": "XP_015134298", "name": "stomatin-like protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134298" }, "gene_names": [ { "name": "STOML1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG1" } ] }, { "name": "STOML1", "type": "synonym", "evidence": [ { "id": "XP_015134298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134298" } ] } ], "protein_names": [ { "name": "Stomatin like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZHG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG1/entry#names_and_taxonomy" } ] }, { "name": "stomatin-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134298" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134298.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134298" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STOML1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG1", "locus": { "chromosome": "10", "start_pos": 2646113, "end_pos": 2642458, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021263", "url": "https://www.ensembl.org/id/ENSGALG00010021263" } ] } } ], "crossref": [ { "id": "A0A8V0ZHG1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHG1", "database": "AlphaFoldDB", "categories": [] }, { "id": "415303", "url": "https://www.ncbi.nlm.nih.gov/gene/415303", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AMHFLSH", "url": "https://omabrowser.org/oma/group/AMHFLSH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHG1", "url": "https://www.orthodb.org/?gene=A0A8V0ZHG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10264:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10264:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134298", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSRSGYQALPLGDFDRFQQSSIGLYGAQKGFFSFGAKADPLGPAMNAADSSQGWLSWICHGIITSLVFLLMLLTFPISGWFALKIVPTYERMVIFRLGRLRAPQGPGVVLLLPFIDHWQRVDLRTRAFNVPPCKLISRDGAVLSMGADVQFRVWDPALSVLVVKDLVAATRMTAQSAMAKALGKKSLREIQGEKLRIGEQLLLDINDMTKSWGLEVDRVELTMEAVLQPPRDALLGPLGAVAPALEGSPPQLAAHLLNSTPSAPEAADSVGTVSEVEPPRRRPSAVELLSAVEPILSEALVSQVGASYQVDIILPGGARSTFFIDLSSGSGRAGCGVPQGSPDVVLEVAEEDLQELMLGELRPLAAYMSGRLRVQGDLQLALRLEELFKAVKLHR", "length": 396, "header": "tr|A0A8V0ZHG1-1|A0A8V0ZHG1_CHICK Isoform 1 of Stomatin like 1 OS=Gallus gallus OX=9031 GN=STOML1 PE=3 SV=1 CANONICAL=A0A8V0ZHG1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG1/entry#A0A8V0ZHG1-1", "sequence": { "sequence": "MFSRSGYQALPLGDFDRFQQSSIGLYGAQKGFFSFGAKADPLGPAMNAADSSQGWLSWICHGIITSLVFLLMLLTFPISGWFALKIVPTYERMVIFRLGRLRAPQGPGVVLLLPFIDHWQRVDLRTRAFNVPPCKLISRDGAVLSMGADVQFRVWDPALSVLVVKDLVAATRMTAQSAMAKALGKKSLREIQGEKLRIGEQLLLDINDMTKSWGLEVDRVELTMEAVLQPPRDALLGPLGAVAPALEGSPPQLAAHLLNSTPSAPEAADSVGTVSEVEPPRRRPSAVELLSAVEPILSEALVSQVGASYQVDIILPGGARSTFFIDLSSGSGRAGCGVPQGSPDVVLEVAEEDLQELMLGELRPLAAYMSGRLRVQGDLQLALRLEELFKAVKLHR", "length": 396, "header": "tr|A0A8V0ZHG1-1|A0A8V0ZHG1_CHICK Isoform 1 of Stomatin like 1 OS=Gallus gallus OX=9031 GN=STOML1 PE=3 SV=1 CANONICAL=A0A8V0ZHG1-1" }, "locus": { "chromosome": "10", "start_pos": 2645654, "end_pos": 2643191, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051543.1", "url": "https://www.ensembl.org/id/ENSGALT00010051543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030734.1", "url": "https://www.ensembl.org/id/ENSGALP00010030734.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SVK9-1", "protein_name": "Stomatin-like protein 1", "gene_name": "STOML1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSRSGYRALPLGDFDRFQQSSFGFLGSQKGCLSPEPGGVGPGADAPQSWPSCFCHGLISFLGFLLLLITFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRTRAFSVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKRPLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSPAGPSLDSTLQQLALHFLGGSVPSVAGGAPRPGPADTLEMVSEVEPSAPHGGAGPSPKQPVAEGLLMALKPILSEALVSQVGACYQFNVILPSGPQSIYFLDLTAGQGRVGHGVPDVIPDVVVELSEEDLRSLLCRELRPLGAYMSGRLKVKGDLAMAMKLEAVLKALK", "length": 398 }, "evidence": [ { "id": "A0A8V0ZHG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZHG1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A7E9-1", "protein_name": "Stomatin-like protein 1", "gene_name": "Stoml1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGRSGYRALPLGDFDRFQQSSFGFLGSQKGCLSPEPGGVGPGADAPESWPSCLCHGLISFLGFLLLLLTFPISGWFALKIVPTYERMIVFRLGRIRNPQGPGMVLLLPFIDSFQRVDLRTRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMAVKDLNAATRMTAHNAMTKALLRRPLQEIQMEKLKIGDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSLAVPSLDSTLQQLALHFLGGSMTSVGRVPSPGSDTLEMINEVEPPASRAGAGTEPSPKQPVAEGLLTALQPFLSESLVSQVGACYQFNVLLPSGTQSIYFLDLTTGQGRVGHGVPDGIPDVVVEMAEADLQALLCKELRPLGAYMSGRLKVKGDLAVVMKLEAVLKALK", "length": 398 }, "evidence": [ { "id": "A0A8V0ZHG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZHG1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HEI5-1", "protein_name": "Stomatin-like protein 1", "gene_name": "Stoml1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFGRSGYRALPLGDFDRFQQSSFGFVGSQKGCLSPEPSGVGPGADAPESWPSCLCHGLISFLGFLLLLLTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRTRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMAVKDLNTATRMTARNAMTKALLRKSLQEIQMEKLKIGDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSPAVPSLDSTLQQLALHLLGGSMNSAVGGAPSSGPVDTLEMISEVEPPACLAGTGPEPSPKQPVAEGLLTALQPFLSEALVSQVGACYQFNVILPSGTQSIYFLDLTAGQGRVGHGAPDGIPDVVVEMAEADLQALLCRELRPLGAYMSGRLKVKGDLAVVMKLEAVLRALK", "length": 400 }, "evidence": [ { "id": "A0A8V0ZHG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZHG1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8CI66-1", "protein_name": "Stomatin-like protein 1", "gene_name": "Stoml1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGRSGYRALPLGDFDRFQQSSFGFLGSQKGCLSPEPGSVGPGADAPESWPSCLCHGLVSVLGFLLLLLTFPISGWFALKIVPTYERMIVFRLGRIRNPQGPGMVLLLPFIDSFQRVDLRTRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMAVKDLNTATRMTAHNAMTKALLRRPLQEIQMEKLKIGDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSLTVPSLDSTLQQLALHLLGGSMNSAVGRVPSPGPDTLEMINEVEPPASLAGAGAEPSPKQPVAEGLLTALQPFLSEALVSQVGACYQFNVILPSGTQSIYFLDLTTGQGRVGHGEPDGIPDVVVEMAEADLQALLSKELRPLGAYMSGRLKVKGDLAVVMKLEAVLKALK", "length": 399 }, "evidence": [ { "id": "A0A8V0ZHG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZHG1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UBI4-1", "protein_name": "Stomatin-like protein 1", "gene_name": "STOML1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGRSGYRALPLGDFDRFQQSSFGFLGSQKGCLSPERGGVGTGADVPQSWPSCLCHGLISFLGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRTRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKRPLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSPAGPNLDSTLQQLALHFLGGSMNSMAGGAPSPGPADTVEMVSEVEPPAPQVGARSSPKQPLAEGLLTALQPFLSEALVSQVGACYQFNVVLPSGTQSAYFLDLTTGRGRVGHGVPDGIPDVVVEMAEADLRALLCRELRPLGAYMSGRLKVKGDLAMAMKLEAVLRALK", "length": 398 }, "evidence": [ { "id": "A0A8V0ZHG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZHG1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ion channel inhibitor activity", "id": "GO:0008200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZHG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG1" }, { "id": "SM00244", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00244" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Band 7", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 246, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 259, "end_pos": 261 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZHH4-1", "uniprot_ac": "A0A8V0ZHH4", "uniprot_id": "A0A8V0ZHH4_CHICK", "mass": { "chemical_mass": 68701.0, "monoisotopic_mass": 68701.0 }, "refseq": {}, "gene_names": [ { "name": "WSCD2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH4" } ] } ], "protein_names": [ { "name": "WSC domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZHH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WSCD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH4", "locus": { "chromosome": "15", "start_pos": 6494659, "end_pos": 6479408, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022309", "url": "https://www.ensembl.org/id/ENSGALG00010022309" } ] } } ], "crossref": [ { "id": "A0A8V0ZHH4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "416887", "url": "https://www.ncbi.nlm.nih.gov/gene/416887", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416887", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416887", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERSNTCG", "url": "https://omabrowser.org/oma/group/ERSNTCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHH4", "url": "https://www.orthodb.org/?gene=A0A8V0ZHH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV87", "url": "https://www.orthodb.org/?gene=A0A8V0ZV87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45964:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45964:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNPPQRRASPWPSRRDEDAMAKLWVKFQRSFRRRPVRFFTLLALYLAAGSLVFLHAGFTGEPRVAGSQRSPGAGEGLGLPYLGATRLSRGFSEVTVGRRRGHWFKGMAKEPAERSRAGDYGAARSRAPKGRGGRDKEEDRARYIGCYVDNTRSRTLRGVSFFDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKVQAPNASESECNMECKGERSSTCGGANRLSIYRLELAQESARRYGSAIFRGCFRQPDNVSIALPASQPMPNMSVDKCVDFCTEKEFPLSALAGTVCRCGFPTTLFPLHEREDEQLCAQRCAGEEFESCGTTEFLLVYQTQVQDNRCMDRRFLPMRSKQLVALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWRGKEWPEFVANYAPWWATHTLDWLRFGRKVLVVHFEDLKQDLFTQLKRMVGLLGIAACEDRLLCVEGQKDGNFKRSGLRKLEYDPYTPEMRKMISGYIRTVDAALKLRNLSGVPDDYYPRRDGDNSTKEEHNMRSSTLGCTEVRWS", "length": 605, "header": "tr|A0A8V0ZHH4-1|A0A8V0ZHH4_CHICK Isoform 1 of WSC domain containing 2 OS=Gallus gallus OX=9031 GN=WSCD2 PE=3 SV=1 CANONICAL=A0A8V0ZHH4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH4/entry#A0A8V0ZHH4-1", "sequence": { "sequence": "MQNPPQRRASPWPSRRDEDAMAKLWVKFQRSFRRRPVRFFTLLALYLAAGSLVFLHAGFTGEPRVAGSQRSPGAGEGLGLPYLGATRLSRGFSEVTVGRRRGHWFKGMAKEPAERSRAGDYGAARSRAPKGRGGRDKEEDRARYIGCYVDNTRSRTLRGVSFFDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKVQAPNASESECNMECKGERSSTCGGANRLSIYRLELAQESARRYGSAIFRGCFRQPDNVSIALPASQPMPNMSVDKCVDFCTEKEFPLSALAGTVCRCGFPTTLFPLHEREDEQLCAQRCAGEEFESCGTTEFLLVYQTQVQDNRCMDRRFLPMRSKQLVALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWRGKEWPEFVANYAPWWATHTLDWLRFGRKVLVVHFEDLKQDLFTQLKRMVGLLGIAACEDRLLCVEGQKDGNFKRSGLRKLEYDPYTPEMRKMISGYIRTVDAALKLRNLSGVPDDYYPRRDGDNSTKEEHNMRSSTLGCTEVRWS", "length": 605, "header": "tr|A0A8V0ZHH4-1|A0A8V0ZHH4_CHICK Isoform 1 of WSC domain containing 2 OS=Gallus gallus OX=9031 GN=WSCD2 PE=3 SV=1 CANONICAL=A0A8V0ZHH4-1" }, "locus": { "chromosome": "15", "start_pos": 6493893, "end_pos": 6484136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054274.1", "url": "https://www.ensembl.org/id/ENSGALT00010054274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032770.1", "url": "https://www.ensembl.org/id/ENSGALP00010032770.1" } ] } }, { "isoform_ac": "A0A8V0ZV87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH4/entry#A0A8V0ZV87-1", "sequence": { "sequence": "MQNPPQRRASPWPSRRDEDAMAKLWVKFQRSFRRRPVRFFTLLALYLAAGSLVFLHAGFTGEPRVAGSQRSPGAGEGLGLPYLGATRLSRGFSEVTVGRRRGHWFKGMAKEPAERSRAGDYGAARSRAPKGRGGRDKEEDRARYIGCYVDNTRSRTLRGVSFFDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKVQAPNASESECNMECKGERSSTCGGANRLSIYRLELAQESARRYGSAIFRGCFRQPDNVSIALPASQPMPNMSVDKCVDFCTEKEFPLSALAGTVCRCGFPTTLFPLHEREDEQLCAQRCAGEEFESCGTTEFLLVYQTQVQDNRCMDRRFLPMRSKQLVALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWRGKEWPEFVANYAPWWATHTLDWLRFGRKVLVVHFEDLKQDLFTQLKRMVGLLGIAACEDRLLCVEGQKDGNFKRSGLRKLEYDPYTPEMRKMISGYIRTVDAALKLRNLSGVPDDYYPR", "length": 579, "header": "tr|A0A8V0ZV87-1|A0A8V0ZHH4_CHICK Computationally mapped isoform of WSC domain containing 2 OS=Gallus gallus OX=9031 GN=WSCD2 PE=3 SV=1 CANONICAL=A0A8V0ZHH4-1" }, "locus": { "chromosome": "15", "start_pos": 6493329, "end_pos": 6484136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054269.1", "url": "https://www.ensembl.org/id/ENSGALT00010054269.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032766.1", "url": "https://www.ensembl.org/id/ENSGALP00010032766.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416887", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416887", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1I1-1", "protein_name": "WSC domain containing 2", "gene_name": "Wscd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKLWFKFQRCFRYFRRKPVRFFTLLAIYLTAGSLVFLHSGFVGQPSVPQSQASPAAGSPAEGGAELPFLGDLHLGRGFRDTVEASSIARRFGPTFKGKDTSERAKLGDYGGAWSRALKGRVVREKEKEKEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKIQAANVSEADCDMDCKGERGSVCGGINRLSVYRLQLAQESARRYGSAVFRGCFRRPNNLSLALPVTVAMPNMSVDKCVDLCTEKEFPLAALAGTACHCGFPTTRFPLHDREDEQLCAQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPAKSKKLIALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDSAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPWWATHTLDWLKFGKTVLVVHFEDLKQDLFTQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTAEMRRTIAAYIRMVDTALRSRNLTGVPEAYGPR", "length": 572 }, "evidence": [ { "id": "A0A8V0ZHH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZHH4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A286ZKC8-1", "protein_name": "WSC domain containing 2", "gene_name": "WSCD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKLWFKFQRYFRRKPVRFFTFLVLYLTAGSLVFLHSGFVGQPAVSQNQANPAVGAPAEGAELPFLGDFNLGRGFRDTGEASSIARRYGPWFKGKDGNERTKLVDYGGAWSRALKGRVIREKEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNCAERGYLYAGLEFGAECYCGHKIQATNVSEAECDMDCKGERGSVCGGANRLSVYRLQLAQESARRYGSAVFRGCFRRPDNLSLALPVTAAMPNMSVDKCVDLCTEKEYPLAALAGTACHCGFPTTRFPLHEREDEQLCAQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPAKSKKLIALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPWWATHTLDWLKFGKKVLVVHFEDLKQDLFVQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYNPYTADMQKTISAYIKMVDAALKGRNLTGVPDDYYPR", "length": 564 }, "evidence": [ { "id": "A0A8V0ZHH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZHH4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2BGL3-1", "protein_name": "Sialate:O-sulfotransferase 2", "gene_name": "wscd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARSLLKIHRYFRRKPVRFFSFILLYLTAGSLVFLHSGFSSDSSTAGIAGSGSDPLLSEGRGGTGGGSATSEGLGLLGRVFKETRRTPRRFGPPWMKESRGQDAPEWAGRGFDHTSSWSHGAKGRTTKEMDDGRAKYIGCYVDDTQKRALRGVSFLDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKIQAPNVSESECNMECKGEKSNLCGGPNRLSIYRLELSQESARRYGSAIFKGCFRRPDNVTLALPASAVMQNMSVDKCVDMCTEKEFSLAALAGDKCHCGFPTPLFNLHEHEDEELCLHRCTGEDFESCGNRDFFVVYQTQVQDNRCMDRRFLPTRSKHLMALASFPGAGNTWARHLIELATGYYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGKKEIETFDASILMIRNPYKALMAEFNRKYGGHIGFASQAHWRGKEWPEFVKNYAPWWASHTLDWLKYGKKVQVVHFEDLKRDLFSQLKGMVIFLGLEVSEDRLLCVEGQKDGNFKRSGLRKLEYDPYTVEMRATIDRLIKTVDMELRKRNLSGVPDEYRPR", "length": 572 }, "evidence": [ { "id": "A0A8V0ZHH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZHH4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4PHA7-1", "protein_name": "Sialate:O-sulfotransferase 2", "gene_name": "Wscd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKLWFKFQRCFRYFRRKPVRFFTLLAIYLTAGSLVFLHSGFVGQPAVPQSQASPAAGSPVEGAELPFLGDLHLGRGFRDTVEASSIARRYGPTFKGKDTSERAKLGDYGGAWSRALKGRVVREKEKEKEEEKAKYIGCYLDDTQSRALRGVSFFDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKIQAANVSESDCDMECKGERGSVCGGINRLSVYRLQLAQESARRYGSAVFRGCFRRPNNLSLALPVSAAMPNMSVDKCVDLCTEKEFPLAALAGTACHCGFPTTRFPLHDREDEQLCAQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPAKSKKLIALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPWWATHTLDWLKFGKTVLVVHFEDLKQDLFTQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTAEMRRTIAAYIRMVDTALRSRNLTGVPDAYGPR", "length": 571 }, "evidence": [ { "id": "A0A8V0ZHH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZHH4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MIR3-1", "protein_name": "WSC domain containing 2", "gene_name": "WSCD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKLWFKFQRYFRRKPVRFFTFLVLYLTAGSLVFLHSGFVGQPAVSQNQANPAVGAPVEGAELTFLGDLNLGRGFRDTGEVSSIARRYGPWFKGKDGNERAKLGDYGGAWSRALKGRVVREKEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKIQAANVSEAECDMDCKGERGSVCGGANRLSVYRLQLAQESARRYGSAVFRGCFRRPDNLSLALPVTAAMPNMSVDKCVDLCTEKEYPLAALAGTACHCGFPTTRFPLHEREDEQLCAQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPAKSKQLIALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPWWATHTLDWLKFGKKVLVVHFEDLKRDLFVQLGRMVGLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTADMQRTISAYIKTVDAALRGRNLTGVPDDYYPR", "length": 564 }, "evidence": [ { "id": "A0A8V0ZHH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZHH4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HVJ1-1", "protein_name": "WSC domain-containing protein 2", "gene_name": "Wscd2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKLWFKFQRCFRYFRRKPVRFFTLLALYLTAGSLVFLHSGFVGQPAVPQSQASPPAGSPAEGAELPFLGDLHLGRSFRDTGEASSIARRYGPSFKGKETSERAKLGDYGGAWSRALKGRVVREKEKEKEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTVFRCQDNCAERGYLYAGLEFGAECYCGHKIQAANVSEAECDMDCKGERGSVCGGVNRLSVYRLQLAQESARRYGSAVFRGCFRRPNNLSLALPVTAAMPNMSVDKCVDLCTEKEYPLAALAGTACHCGFPTTRFPLHDREDEQLCAQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPAKSKKLIALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPWWATHTLDWLKFGKTVLVVHFEDLKQDLFAQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTAEMRRTIAAYIRMVDTALRSRNLTGVPDAYGPR", "length": 571 }, "evidence": [ { "id": "A0A8V0ZHH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZHH4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q2TBF2-1", "protein_name": "Sialate:O-sulfotransferase 2", "gene_name": "WSCD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKLWFKFQRYFRRKPVRFFTFLALYLTAGSLVFLHSGFVGQPAVSGNQANPAAAGGPAEGAELSFLGDMHLGRGFRDTGEASSIARRYGPWFKGKDGNERAKLGDYGGAWSRALKGRVVREKEEERAKYIGCYLDDTQSRALRGVSFFDYKKMTIFRCQDNCAERGYLYGGLEFGAECYCGHKIQATNVSEAECDMECKGERGSVCGGANRLSVYRLQLAQESARRYGSAVFRGCFRRPDNLSLALPVTAAMLNMSVDKCVDFCTEKEYPLAALAGTACHCGFPTTRFPLHDREDEQLCAQKCSAEEFESCGTPSYFIVYQTQVQDNRCMDRRFLPGKSKQLIALASFPGAGNTWARHLIELATGFYTGSYYFDGSLYNKGFKGERDHWRSGRTICIKTHESGQKEIEAFDAAILLIRNPYKALMAEFNRKYGGHIGFAAHAHWKGKEWPEFVRNYAPWWATHTLDWLKFGKKVLVVHFEDLKQDLFVQLGRMVSLLGVAVREDRLLCVESQKDGNFKRSGLRKLEYDPYTADMQKTISAYIKMVDAALKGRNLTGVPDDYYPR", "length": 565 }, "evidence": [ { "id": "A0A8V0ZHH4", "url": "https://omabrowser.org/oma/group/A0A8V0ZHH4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZHH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHH4" }, { "id": "PS51212", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51212" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WSC", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 233, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 584, "end_pos": 586 } ] }, 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This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025006658.1. 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The reference sequence was derived from JAENSK010000257.1. On Dec 1, 2021 this sequence version replaced NP_001316433.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001316433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316433" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHL3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYP2AC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHL3", "locus": { "chromosome": "14", "start_pos": 2257215, "end_pos": 2250142, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022329", "url": "https://www.ensembl.org/id/ENSGALG00010022329" } ] } } ], "crossref": [ { "id": "A0A8V0ZHL3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHL3", "database": 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"protein_names": [ { "name": "Ras homolog family member D", "type": "synonym", "evidence": [ { "id": "A0A8V0ZHM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RHOD", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZHM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "776504", "url": "https://www.ncbi.nlm.nih.gov/gene/776504", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:776504", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776504", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VHISLWD", "url": "https://omabrowser.org/oma/group/VHISLWD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHM2", "url": "https://www.orthodb.org/?gene=A0A8V0ZHM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPR7", "url": "https://www.orthodb.org/?gene=A0A8V0ZPR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPLPGSQSSAAGPPEPTVAEIKAVVVGDGGCGKTSLLMVFARGDFPKVYVPTVFEKYTASFRIRGKPAKIHLWDTAGQEDYDRLRPLSYSDTNVVLICFDVTSRSSYDNILTKWYPEVNHFCKGVPVLLVGCKTDLRQGHHESVTFLEVSAATPCGTDTSHVPPHLPEAQHRCPQGEAMARQVQAAAYLECSALHQDNVRDVFIEACTIALRGGHRHRRKKRHRNGCVLC", "length": 231, "header": "tr|A0A8V0ZHM2-1|A0A8V0ZHM2_CHICK Isoform 1 of Ras homolog family member D OS=Gallus gallus OX=9031 GN=RHOD PE=3 SV=1 CANONICAL=A0A8V0ZHM2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2/entry#A0A8V0ZHM2-1", "sequence": { "sequence": "MQPLPGSQSSAAGPPEPTVAEIKAVVVGDGGCGKTSLLMVFARGDFPKVYVPTVFEKYTASFRIRGKPAKIHLWDTAGQEDYDRLRPLSYSDTNVVLICFDVTSRSSYDNILTKWYPEVNHFCKGVPVLLVGCKTDLRQGHHESVTFLEVSAATPCGTDTSHVPPHLPEAQHRCPQGEAMARQVQAAAYLECSALHQDNVRDVFIEACTIALRGGHRHRRKKRHRNGCVLC", "length": 231, "header": "tr|A0A8V0ZHM2-1|A0A8V0ZHM2_CHICK Isoform 1 of Ras homolog family member D OS=Gallus gallus OX=9031 GN=RHOD PE=3 SV=1 CANONICAL=A0A8V0ZHM2-1" }, "locus": { "chromosome": "5", "start_pos": 85942, "end_pos": 84873, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054339.1", "url": "https://www.ensembl.org/id/ENSGALT00010054339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032820.1", "url": "https://www.ensembl.org/id/ENSGALP00010032820.1" } ] } }, { "isoform_ac": "A0A8V0ZPR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2/entry#A0A8V0ZPR7-1", "sequence": { "sequence": "MQPLPGSQSSAAGPPEPTVAEIKAVVVGDGGCGKTSLLMVFARGDFPKVYVPTVFEKYTASFRIRGKPAKIHLWDTAGQEDYDRLRPLSYSDTNVVLICFDVTSRSSYDNILTKWYPEVNHFCKGVPVLLVGCKTDLRQGHHESVTFLEGEAMARQVQAAAYLECSALHQDNVRDVFIEACTIALRGGHRHRRKKRHRNGCVLC", "length": 204, "header": "tr|A0A8V0ZPR7-1|A0A8V0ZPR7_CHICK Computationally mapped isoform of Ras homolog family member D OS=Gallus gallus OX=9031 GN=RHOD PE=3 SV=1 CANONICAL=A0A8V0ZHM2-1" }, "locus": { "chromosome": "5", "start_pos": 85942, "end_pos": 84873, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054343.1", "url": "https://www.ensembl.org/id/ENSGALT00010054343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032824.1", "url": "https://www.ensembl.org/id/ENSGALP00010032824.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 18, "start_aa": "Thr", "end_pos": 18, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr18", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:776504", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776504", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ADM8-1", "protein_name": "Ras homolog family member D", "gene_name": "Rhod", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNASQTEGEEAPHSGRPIKVVLVGDGGCGKTSLMMVFANGAFPESYNPTVFERYNATLQMKGKPVRLQIWDTAGQDDYDRLRPLFYPDANVLLLCFDVTNPNSFDNVSNRWYPEVTHFCKGVPIIVVGCKIDLRKDKVLVNTLRKKRLEPVTYHRGHDMARSVGAVAYLECSARLHDNVEAVFQEAAEVALSSRSHNFWRRITQNFCVVT", "length": 210 }, "evidence": [ { "id": "A0A8V0ZHM2", "url": "https://omabrowser.org/oma/group/A0A8V0ZHM2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LKS1-1", "protein_name": "Ras homolog family member D", "gene_name": "RHOD", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKAARAEREEVKVVLVGDGGCGKTSLLMVFAEGAFPESYTPTVFERLGVNLQMKGGPVRLQIWDTAGQVDYDRLRPLFYPDASVLLLCFDVTSPHSFDNISNRWYPEVNHFCKEVPIIVVGCKTDLRKDKSLVKKLRKNGLEPVTYHRGQEMARAVGAVAYLECSALLQENVQAVFQEAAEVALSSRSRNFWRRITRSFCVLT", "length": 203 }, "evidence": [ { "id": "A0A8V0ZHM2", "url": "https://omabrowser.org/oma/group/A0A8V0ZHM2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O00212-1", "protein_name": "Rho-related GTP-binding protein RhoD", "gene_name": "RHOD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAAQAAGEEAPPGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDNVHAVFQEAAEVALSSRGRNFWRRITQGFCVVT", "length": 210 }, "evidence": [ { "id": "A0A8V0ZHM2", "url": "https://omabrowser.org/oma/group/A0A8V0ZHM2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2" } ], "pmid": "" }, { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 18 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZHN8-1", "uniprot_ac": "A0A8V0ZHN8", "uniprot_id": "A0A8V0ZHN8_CHICK", "mass": { "chemical_mass": 22238.0, "monoisotopic_mass": 22238.0 }, "refseq": {}, "gene_names": [ { "name": "USMG5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHN8" } ] } ], "protein_names": [ { "name": "Up-regulated during skeletal muscle growth 5 homolog (mouse)", "type": "synonym", "evidence": [ { "id": "A0A8V0ZHN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHN8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHN8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USMG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHN8", "locus": { "chromosome": "6", "start_pos": 24391742, "end_pos": 24398769, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021118", "url": "https://www.ensembl.org/id/ENSGALG00010021118" } ] } } ], "crossref": [ { "id": "A0A8V0ZHN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR009125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR34038", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34038", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34038:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34038:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14960", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14960", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHN8", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZQ21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFRFCGDLDCPDWVLAEISVLARISSVKLKLICAQVLRELLGETIDYEKILKLTSDAKLESGDVKAAIAVLDFILSNAAKHNVDGESLSSELQQLGLPKGGAWGGDTGGPAAAHLHQVLPRRAQSYSEQCTMLAVLSYVHAGCPQGDPWLSEPYPVPSPLGFGCPRAGAGSSGCSLLLPSSFSGRTRHGVVPLLRGEAELPAGQPQGWQPPIEPPGWRVVAGGLRTELQRAAGGGRTSGAPAAACAAPGARGARGRAHGRVGGEVPGAAGRAEAGPGADEDPPLRTRPPAVVSQRAGPDNKVRERSP", "length": 308, "header": "tr|A0A8V0ZHP7-1|A0A8V0ZHP7_CHICK Isoform 1 of COMM domain containing 4 OS=Gallus gallus OX=9031 GN=COMMD4 PE=1 SV=1 CANONICAL=A0A8V0ZHP7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHP7/entry#A0A8V0ZHP7-1", "sequence": { "sequence": "MRFRFCGDLDCPDWVLAEISVLARISSVKLKLICAQVLRELLGETIDYEKILKLTSDAKLESGDVKAAIAVLDFILSNAAKHNVDGESLSSELQQLGLPKGGAWGGDTGGPAAAHLHQVLPRRAQSYSEQCTMLAVLSYVHAGCPQGDPWLSEPYPVPSPLGFGCPRAGAGSSGCSLLLPSSFSGRTRHGVVPLLRGEAELPAGQPQGWQPPIEPPGWRVVAGGLRTELQRAAGGGRTSGAPAAACAAPGARGARGRAHGRVGGEVPGAAGRAEAGPGADEDPPLRTRPPAVVSQRAGPDNKVRERSP", "length": 308, "header": "tr|A0A8V0ZHP7-1|A0A8V0ZHP7_CHICK Isoform 1 of COMM domain containing 4 OS=Gallus gallus OX=9031 GN=COMMD4 PE=1 SV=1 CANONICAL=A0A8V0ZHP7-1" }, "locus": { "chromosome": "10", "start_pos": 2664879, "end_pos": 2663247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051690.1", "url": "https://www.ensembl.org/id/ENSGALT00010051690.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030829.1", "url": "https://www.ensembl.org/id/ENSGALP00010030829.1" } ] } }, { "isoform_ac": "A0A8V0ZQ21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHP7/entry#A0A8V0ZQ21-1", "sequence": { "sequence": "MRFRFCGDLDCPDWVLAEISVLARISSVKLKLICAQVLRELLGETIDVSVPTGNHASSQASALAVMCASVLQYEKILKLTSDAKLESGDVKAAIAVLDFILSNAAKHNVDGESLSSELQQLGLPKEHATGLCRSYEEKQSSLQDSLRAGSLRLSRLDGVSWRVDYALSSSELQEVGEPLVHLLLRVRHREHGEPEAVPMAVSAEKFRVLLAELKQAQALMKTLL", "length": 224, "header": "tr|A0A8V0ZQ21-1|A0A8V0ZQ21_CHICK Computationally mapped isoform of COMM domain containing 4 OS=Gallus gallus OX=9031 GN=COMMD4 PE=1 SV=1 CANONICAL=A0A8V0ZHP7-1" }, "locus": { "chromosome": "10", "start_pos": 2664808, "end_pos": 2663247, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051694.1", "url": "https://www.ensembl.org/id/ENSGALT00010051694.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030833.1", "url": "https://www.ensembl.org/id/ENSGALP00010030833.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZHQ3-1", "uniprot_ac": "A0A8V0ZHQ3", "uniprot_id": "A0A8V0ZHQ3_CHICK", "mass": { "chemical_mass": 116594.0, "monoisotopic_mass": 116594.0 }, "refseq": { "ac": "XP_040507223", "name": "tetratricopeptide repeat protein 34", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507223" }, "gene_names": [ { "name": "TTC34", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ3" } ] }, { "name": "TTC34", "type": "synonym", "evidence": [ { "id": "XP_040507223", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507223" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat domain 34", "type": "synonym", "evidence": [ { "id": "A0A8V0ZHQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ3/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 34", "type": "synonym", "evidence": [ { "id": "XP_040507223", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507223" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040507223", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507223" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTC34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ3", "locus": { "chromosome": "21", "start_pos": 1370455, "end_pos": 1358364, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019666", "url": "https://www.ensembl.org/id/ENSGALG00010019666" } ] } } ], "crossref": [ { "id": "A0A8V0ZHQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100857353", "url": "https://www.ncbi.nlm.nih.gov/gene/100857353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HWDGMAV", "url": "https://omabrowser.org/oma/group/HWDGMAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHQ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZHQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44874", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44874", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44874:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44874:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040507223", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507223", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPQGLAALLCREGDQHLAQQELPTATAFYVAAFSCSAPTALQKVNSLENGLWERVIATLEMWCRGKSQIPKIQSKNVAIASLRVEIAAVFLSTLSPDNVLSSVYKLEALLRRGCSEEVVSKCNVLLKAHPKYSVELLLLRALAWVLSGTQIRKGVADYIQVFVRHQAEAVAYVCTRQKEHLPQIIQAFSNFLSTYQKESPDGSSLDHWLGNCYAFLSAVAPGDVWVCRAQAAYLFKKSKFEECVAVCSKALRGLSVDNSLRDEKMLGLLLERAAAYFFLGGRMQEMMQDLAEAFAASPDLAMKHFEELFSPPDTEKIEEQARTVLEVKFAAYREAVRARTELRSNRCTELLPSVIQTVLFLLRISPGSKRELSVRLADCHLLHGHIGAALEICDQLLAAEQKTYHNTLLALRGFCALHSHDHQQALQDFQKVIEHDSPHPNSCIKALCGRGLIRISGGSHYLTALDYITACQLKLEETIFTIKAYVPWNQRGLLLKVLQEEGQKMLQKKRDALGVYQLASLLMELDPSDEASRILCADALYQMGWVEEAHKLLSLALSRNPQRSPILARLALLQLKKGFMYDGNQLLKKVIKLGDTSCLLPIMDIFKDEDRKLMQTHCRSRALSILKNKREDADIKEAIAYLSFAIIASGGYAEDCLLIRAQCYGHLGQKKTAIFDFNAVLKEDPGNVHALSGRGLIYLALKQQKEAVQDLILALKAEAGMVIPAILSLKHEAQELVAQWLLQHSRTVLAELVATKDFSKEERTLRDLLVIAGALIKVRKEAQYHTFYTDVLIANGRYEEALAHLQEAFGHSLADELASARLAVLQLKKRNVPAAAHSFSILAKKDERELEFLLNFVDAKQQQHLSQVAAQEGNVLIKGYHYKKALGYFTLAILTSKDNPRYLRQRAACFMHLKKYDKALKDMEKVIEKHGCNSLRTRVQDHCSKGYLLLSVSEEGAAVKQYIEALQLDESTALCSIMNGSGSENVAKTFHKIAQCNFESQHYEEAWKITDYGLKIDQNNPDLKKLKTRLKREASGCSIH", "length": 1041, "header": "tr|A0A8V0ZHQ3-1|A0A8V0ZHQ3_CHICK Isoform 1 of Tetratricopeptide repeat domain 34 OS=Gallus gallus OX=9031 GN=TTC34 PE=4 SV=1 CANONICAL=A0A8V0ZHQ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ3/entry#A0A8V0ZHQ3-1", "sequence": { "sequence": "MSPQGLAALLCREGDQHLAQQELPTATAFYVAAFSCSAPTALQKVNSLENGLWERVIATLEMWCRGKSQIPKIQSKNVAIASLRVEIAAVFLSTLSPDNVLSSVYKLEALLRRGCSEEVVSKCNVLLKAHPKYSVELLLLRALAWVLSGTQIRKGVADYIQVFVRHQAEAVAYVCTRQKEHLPQIIQAFSNFLSTYQKESPDGSSLDHWLGNCYAFLSAVAPGDVWVCRAQAAYLFKKSKFEECVAVCSKALRGLSVDNSLRDEKMLGLLLERAAAYFFLGGRMQEMMQDLAEAFAASPDLAMKHFEELFSPPDTEKIEEQARTVLEVKFAAYREAVRARTELRSNRCTELLPSVIQTVLFLLRISPGSKRELSVRLADCHLLHGHIGAALEICDQLLAAEQKTYHNTLLALRGFCALHSHDHQQALQDFQKVIEHDSPHPNSCIKALCGRGLIRISGGSHYLTALDYITACQLKLEETIFTIKAYVPWNQRGLLLKVLQEEGQKMLQKKRDALGVYQLASLLMELDPSDEASRILCADALYQMGWVEEAHKLLSLALSRNPQRSPILARLALLQLKKGFMYDGNQLLKKVIKLGDTSCLLPIMDIFKDEDRKLMQTHCRSRALSILKNKREDADIKEAIAYLSFAIIASGGYAEDCLLIRAQCYGHLGQKKTAIFDFNAVLKEDPGNVHALSGRGLIYLALKQQKEAVQDLILALKAEAGMVIPAILSLKHEAQELVAQWLLQHSRTVLAELVATKDFSKEERTLRDLLVIAGALIKVRKEAQYHTFYTDVLIANGRYEEALAHLQEAFGHSLADELASARLAVLQLKKRNVPAAAHSFSILAKKDERELEFLLNFVDAKQQQHLSQVAAQEGNVLIKGYHYKKALGYFTLAILTSKDNPRYLRQRAACFMHLKKYDKALKDMEKVIEKHGCNSLRTRVQDHCSKGYLLLSVSEEGAAVKQYIEALQLDESTALCSIMNGSGSENVAKTFHKIAQCNFESQHYEEAWKITDYGLKIDQNNPDLKKLKTRLKREASGCSIH", "length": 1041, "header": "tr|A0A8V0ZHQ3-1|A0A8V0ZHQ3_CHICK Isoform 1 of Tetratricopeptide repeat domain 34 OS=Gallus gallus OX=9031 GN=TTC34 PE=4 SV=1 CANONICAL=A0A8V0ZHQ3-1" }, "locus": { "chromosome": "21", "start_pos": 1369741, "end_pos": 1358563, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047455.1", "url": "https://www.ensembl.org/id/ENSGALT00010047455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028109.1", "url": "https://www.ensembl.org/id/ENSGALP00010028109.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287B552-1", "protein_name": "Tetratricopeptide repeat domain 34", "gene_name": "TTC34", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMSAQELVACLCQEGDQHLALGDTPLAAAFYLAAFSCHAPSAVRHVRATLAEVQGSPVVATLEAWCRGDSQIPAIHWDGMVVVSLTGTMASALLATLCPEHPATVLHSLASLLARGRHEEVVQRCGALLDTHCQQTLELQLTRALACILSGTQTDDGVADYLQAFATSADRTVAFIHTHQQPYLPALVSTLQGYVVGHQEAGNSASQQETDCWELLAALDPGGTWSNALSPEALLRRGRYADCKEACSQALDVDPAGSRPQGARLATLLVTRAAAAFFLNSRAQDLLRDLHEAFHESPSAARKQFESVLSTTDQACLRARVLEAAEVGFTHFQEAVRNRPELREDSDRELLAPVTRALRVLVRMAPPGARPALGTRLAECLLLAGDAAGARALCERLLRPSHTGDRARDRAPLLALRGFCALHTGDTQRAQEDFQKVVELGPPHPGSCLRALCGRGLLRVLAGSEFLGALDYVTACRLRLEEALLVTKAYVPWNQRGLLLTVLREEGRRMLQRRPDPGSKSAPGCRRKAAEIHGPVAQEGVAHGVYQLATLLTELDSEDEASRLLVADALYRLGRLDDAHKALLVALSRRPQAAPVLVRLALLQLRRGFLYDANQLVKKVVQSRDTACLQPTLDVFHHEDRQRLRGHCHARALSILRARPGGAEGGAHTREAIAYLSLAIFAAGSQASESLLARARCYGFLGRKKTAMFDFNSVLRAEPGNTQALCGRALLHLALDQQKEAVDDILSALQRGPSTAVPEIRSLKPEAQALITQGLSSRCRALLSQLRDTGARLSDKDTQSLLAAGKALIEIDAGQPGWHVLLADVLATVGSFEEAGTCLQKVLQPTPPTEAARARRGLLRLKKGDVLAAAHDLQCLAESDTQDLGFLLRLLEASEQQRLTQAAAQEADTLLNSGQPGQALGYCSLAVLAGGGQACHLRLRATCLAELHEFGRALRDLDHVLQEGSGDSDLQTQAADFCSQGRLLLNLGDEAGAARAFSQALKLAPTLAQSSLQEQPGKAPTTRALLCRAQRCLEEQCYTEAWTAAEGGLLVDPEHRGLKRLKARLRRETSSGCRLH", "length": 1076 }, "evidence": [ { "id": "A0A8V0ZHQ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZHQ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A8MYJ7-1", "protein_name": "Tetratricopeptide repeat protein 34", "gene_name": "TTC34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQRSPRAGPSRAQGRREAAETGGPTTQEGVACGVHQLATLLMELDSEDEASRLLAADALYRLGRLEETHKALLVALSRRPQAAPVLARLALLQLRRGFFYDANQLVKKLVQSGDTACLQPTLDVFCHEDRQLLQGHCHARALAILRARPGGADGRVHTKEAIAYLSLAIFAAGSQASESLLARARCYGFLGQKKTAMFDFNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGPGTVVPELRSLKPEAQALITQGLYSHCRALLSQLPDTGAPLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQGSYEEAGTHLEKALHRAPTSEAARARLGLLQLKKGDVPGAARDLQSLAEVDAPDLSCLLHLLEASERQSLAQAAAQEAGTLLDAGQPRQALGYCSLSVLASGSSACHLRLRATCLAELQEFGRALRDLDHVLQEALGDGDLPRRAEDFCRQGRLLLSLGDEAAAAGAFAQALKLAPSLAQNSLCRQPGRAPTARMFLLRGQCCLEEQRHAEAWTAVESGLLVDPDHRGLKRLKARIRREASSGCWLQ", "length": 566 }, "evidence": [ { "id": "A0A8V0ZHQ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZHQ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZC99-1", "protein_name": "Tetratricopeptide repeat domain 34", "gene_name": "Ttc34", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAQDLVACLCQEGDKHLALGELPLATAFYLAAFSCHAPSAVRHVRAVLTESPGAPVVATLEAWCRGNSQIPAIHWDGMAVVSLTGTLASAFLGAICPDHPATVLYPLAGLLAQGRHVEVVQRCNTLLDAHSQQALELQLMRALAWVLSVDQAREGIAAYLQNFASSADRTVAFIRSHQQPYLPRLLGTLQNYLSGHLKTSASQQEANCRGLLEALDPRGSWMGAMSPEALLHRGRFEDCQAACSRDLQPDSTGSRPQGEHLAALLVTRAAATFFQDGPVGDMLRDLHEAFSESPIGARRQFQALLSSEDRERLQAQAKEAADLGFARFLEAVRSRVELRRDADRELLVPVTRALRVLLRVAPARRRPALGTRLAECLLLAGDVAGARAQCERLLRPRRPGERAGNHTGEHAPLLALRGFCALHAGDAQRAREDFQAVVERAAPHAGGCVRALCGRGLLRVLAGSAFLGALDYVTACRLRPEEALLVAKAYVPWNQRGLLLTVLREEGRKMLLRSPSYAVKAAQAQEGDAYGVYQLATLLTEMDAGDETSCLLAVDALYRLGRLEDAHKSLLVALSRRPQAAPVLVRLALLQLRRGFCYDANQLVKKVAQSGDTACLQHTLDIFRREDLQLLQDHCHTRALSILRARPGGSDSEAHTREAIAYLSLAIFTAGSRASESLLVRARCYGLLGQKKTAMFDFNSILREEPGNVKALCGRALVHLALDQLQEAVDDMISALKLDPGTVITEILSLKTEVQLPLTQGLYTRSRALLNQCLDAGVPLREEDTQGLLATGEALIRINAAQSSWHLLLTDILTGLGKYQEAGTHLQEALHLTPSSEATQARRGLLQLKKGDVSAAARDLRCLAEIDTQDLSFLLRLLESAERQSLMQTAAKEASNLLDLGNPGQALSYCSLAILAGGSSPYHLRLRMACLTQLQEYDRALRDLDRVLYQPTEDSDLPRRTEDLCTRGRLLLSLGDKDGAAGAFTQALALAPAQAQSSLLEQPGRATTASVFLIHGQRCLEKQHFEEAWTAVRNGLLVDPSHSGLKKLKLRTRKEAASGCRLH", "length": 1064 }, "evidence": [ { "id": "A0A8V0ZHQ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZHQ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C0Q3-1", "protein_name": "Tetratricopeptide repeat protein 34", "gene_name": "Ttc34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLRSPSYAGKAAQAQEGDAYGVYQLATLLIGMDAEDETSCLLAADALYRLGRLDDAHKSLLVALSQRPQAAPVLVRLALLQLRRGFCYDANQLVKKVAQSGDTACLQHMLDIFHHEDLQLLQDHCHTRALSILRARPGGSDSEAHTREAIAYLSLAIFAAGSGGSESLLVRARCYGLLGQKKTAMFDFNAILREEPGNVKALCGRALVHLALDQLQEAVDDMVSALKLDPGTVIPEILSLKTEVQLPLTQGLYTRCRVLLNQCLHTGVPLREEDTQGLLAMGKALIRINATQPSWRLLLTDILTGLGKYQEAGTHLQEALHLTPSSEAAQARQGLLQLKKGDVSAAVHGLQCLAERDTQDLGFLLCLLDSPERQSLVQTAAKEASNILDLGNPGQALSYCSLAILAGGNNPYHLRLRVACLTQLQEYDRALRDLDRVLQHPAEDSDLPRQSEDFCTRGRLLLSLGDKDGAAGAFTQALALAPAQAQNSLLEQPGQAMTASVFLIHGQRCLEEEHFEEAWTAVQNGLLVDPSHSGLKKLKLRTRKVATSGCRLH", "length": 554 }, "evidence": [ { "id": "A0A8V0ZHQ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZHQ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 980, "end_pos": 982, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 980, "end_pos": 982 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZHS7-1", "uniprot_ac": "A0A8V0ZHS7", "uniprot_id": "A0A8V0ZHS7_CHICK", "mass": { "chemical_mass": 199638.0, "monoisotopic_mass": 199638.0 }, "refseq": { "ac": "NP_001032925", "name": "lymphocyte antigen 75 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032925" }, "gene_names": [ { "name": "LY75", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7" } ] }, { "name": "DEC205", "type": "synonym", "evidence": [ { "id": "NP_001032925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032925" } ] }, { "name": "LY75", "type": "synonym", "evidence": [ { "id": "NP_001032925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032925" } ] } ], "protein_names": [ { "name": "Lymphocyte antigen 75", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7/entry#names_and_taxonomy" } ] }, { "name": "DEC-205 protein", "type": "synonym", "evidence": [ { "id": "NP_001032925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032925" } ] }, { "name": "DEC-205", "type": "synonym", "evidence": [ { "id": "A0A8V0ZHS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7/entry#names_and_taxonomy" } ] }, { "name": "lymphocyte antigen 75 precursor", "type": "synonym", "evidence": [ { "id": "NP_001032925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032925" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ574899.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000236.1. On Sep 23, 2021 this sequence version replaced NP_001032925.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001032925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032925" } ] }, { "annotation": "Data indicate thata the expression of DEC205 in normal birds had a characteristic distribution in the primary lymphoid organs.", "evidence": [ { "database": "RefSeq", "id": "NP_001032925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032925" }, { "database": "PubMed", "id": "23326318", "url": "https://glygen.org/publication/PubMed/23326318" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LY75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7", "locus": { "chromosome": "7", "start_pos": 21546560, "end_pos": 21505577, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021125", "url": "https://www.ensembl.org/id/ENSGALG00010021125" } ] } } ], "crossref": [ { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00062", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00062", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424192", "url": "https://www.ncbi.nlm.nih.gov/gene/424192", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424192", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424192", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHEIYTK", "url": "https://omabrowser.org/oma/group/YHEIYTK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHS7", "url": "https://www.orthodb.org/?gene=A0A8V0ZHS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22803", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22803", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00040", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00040", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001032925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032925", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRPAGRCAAACCIAWLLACCAARRDDTGSGAFTIRHDTLNKCIQVKNSRIVVDDCKETSEALWKWVSQSRLFHLGTKQCLGLDIFTKLPSRLRMVDCNSDLRLWWRCADGSVVGASQYKVTVRSAYVTASINASDQWRSNNSSADICQYPYHEVYTKDGNSYGKPCEFPFLYNMTWHHDCIQDGTHTSRKWCATSEDYTRDGKWGICLQPEDGCHDIWEHDASSQHCYQFNTQSALSWKEAYVSCQRQGGDLLSIQDASELNYIQAKDDIAEIFWIGLNQLDVSRGWQWSDHKPLNFVNWHPDMWDLSPLDGTSCVAMNAASGQWRSYHCGNPLPYVCKKSFKEVSNLTEFWRHVNTRCDAGWLPHNGFCYMLIHNQASWSTADQLCKANKSNLISIHSLADVELIVTKLHNDAREEVWVGLRNEDVPTLFKWSDRTDVVFTYWDQNEPSVPFNATPNCVSYSGKLGQWRVKSCEENLKYVCKKKGKILNETKSDKNCSLDEGWEMHGNYCYKILNTELSFGAECNLTVTNRFEQEFINSLIRKHTKVEEKYFWTGLQDISQSGMYSWAAVDGEKSEAVTYTNWNSLQPEFSGGCVAMSSGRSLGKWETKDCKTTKAFPVCKKYIGLPKEPEVLPKPSDPCPPGWHNGSGLSCYKFFHSERVLRTRTWEEAERFCEALGGHLPSFTHTEEIKTLHSILRKIISNDRWVWVGMNKRSPDSLGTWQWSDDKPVTSLVLPHDYLEDEYDTRDCVALKTFQFSRRSFWRFYFHEGRDLEFYFKPFDCEAKLEWVCQITKGSTPKTPEWYIPDEIGIHGVPLVVDGAELWFVPDKNVSFQEAISYCQKNDSELASVESYPKLRTILSQIEKLSNSEQKWWLKFIDYGYSYHSPLQLFPRFHDRSLRDCWYVSRKSWYRDYPVNCNMKLPFICEKNNASLLEKHDPSYRPVTGGCPKGWLRFRNKCFLKMKSEYLTFNAANEKCVTFGGSLPCISSQAEQDFITSLLPQMPRDIWIGLQFLFSTRENKWIDESRLLYSNFHPLLTGRLRKIPLDLFDEEFNNQCGVILNDPKSHYVGTWNFTACADRHFLGICQRPIGIGAADNQTEQVLNDTFSYHNVQYKLILNNLTWNDAMAACIGQKMQLVSITDQFQQASLAVQAALHDYPLWIGLFSRDGGKHYGWLDGKHVSFSRWSEDDEETSEECVYLDTDGFWKTSDCYSENRGAICYSSEKKDEKEQVTQVKCPHKIKNTPWISFRNNCYTFMITKNRWREMKSQEAHHLCKKMNPEAFVLSVRDEEENNFVAEQLHSFSGLAVWVWLGVIYDDSDKVLKWYDETYLTYNNWRLGRPIIKKNSFFAGVNLDGFWDIYNYSQSWQAHHYNVYSILACKIERGPQQHKPPLPEFIPHGDVTYRILQKKLTWYDAVRECKQNMSDLASVHSESQQLFLEDIVKQDGYSLWLGLSIHDGSKANFEWSDGSSFDYYPWELENSNTTENCVLLDTKGSWNRAKCTNVAEGAICYSFSNKKQLEQKQVSRASGCSQLSGELPWIQYKDHCYAFDMAFYNFSVYNVEDAKKVCKKLNPSAALLTIGDAEENAFVSAHIKKNDLITRKVWLGLTQSSTGQTLHWLDGSSVNYANWDNRTTELSEKCSVITSTTGKWSKVDCSRSQSRVVCKAPLGSNHTGVAVAFALLVILVLVLGLVWFICKKKRLHWSAFSSVHYQRGLNDDEADDVFTKDGY", "length": 1732, "header": "tr|A0A8V0ZHS7-1|A0A8V0ZHS7_CHICK Isoform 1 of Lymphocyte antigen 75 OS=Gallus gallus OX=9031 GN=LY75 PE=1 SV=1 CANONICAL=A0A8V0ZHS7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7/entry#A0A8V0ZHS7-1", "sequence": { "sequence": "MGRPAGRCAAACCIAWLLACCAARRDDTGSGAFTIRHDTLNKCIQVKNSRIVVDDCKETSEALWKWVSQSRLFHLGTKQCLGLDIFTKLPSRLRMVDCNSDLRLWWRCADGSVVGASQYKVTVRSAYVTASINASDQWRSNNSSADICQYPYHEVYTKDGNSYGKPCEFPFLYNMTWHHDCIQDGTHTSRKWCATSEDYTRDGKWGICLQPEDGCHDIWEHDASSQHCYQFNTQSALSWKEAYVSCQRQGGDLLSIQDASELNYIQAKDDIAEIFWIGLNQLDVSRGWQWSDHKPLNFVNWHPDMWDLSPLDGTSCVAMNAASGQWRSYHCGNPLPYVCKKSFKEVSNLTEFWRHVNTRCDAGWLPHNGFCYMLIHNQASWSTADQLCKANKSNLISIHSLADVELIVTKLHNDAREEVWVGLRNEDVPTLFKWSDRTDVVFTYWDQNEPSVPFNATPNCVSYSGKLGQWRVKSCEENLKYVCKKKGKILNETKSDKNCSLDEGWEMHGNYCYKILNTELSFGAECNLTVTNRFEQEFINSLIRKHTKVEEKYFWTGLQDISQSGMYSWAAVDGEKSEAVTYTNWNSLQPEFSGGCVAMSSGRSLGKWETKDCKTTKAFPVCKKYIGLPKEPEVLPKPSDPCPPGWHNGSGLSCYKFFHSERVLRTRTWEEAERFCEALGGHLPSFTHTEEIKTLHSILRKIISNDRWVWVGMNKRSPDSLGTWQWSDDKPVTSLVLPHDYLEDEYDTRDCVALKTFQFSRRSFWRFYFHEGRDLEFYFKPFDCEAKLEWVCQITKGSTPKTPEWYIPDEIGIHGVPLVVDGAELWFVPDKNVSFQEAISYCQKNDSELASVESYPKLRTILSQIEKLSNSEQKWWLKFIDYGYSYHSPLQLFPRFHDRSLRDCWYVSRKSWYRDYPVNCNMKLPFICEKNNASLLEKHDPSYRPVTGGCPKGWLRFRNKCFLKMKSEYLTFNAANEKCVTFGGSLPCISSQAEQDFITSLLPQMPRDIWIGLQFLFSTRENKWIDESRLLYSNFHPLLTGRLRKIPLDLFDEEFNNQCGVILNDPKSHYVGTWNFTACADRHFLGICQRPIGIGAADNQTEQVLNDTFSYHNVQYKLILNNLTWNDAMAACIGQKMQLVSITDQFQQASLAVQAALHDYPLWIGLFSRDGGKHYGWLDGKHVSFSRWSEDDEETSEECVYLDTDGFWKTSDCYSENRGAICYSSEKKDEKEQVTQVKCPHKIKNTPWISFRNNCYTFMITKNRWREMKSQEAHHLCKKMNPEAFVLSVRDEEENNFVAEQLHSFSGLAVWVWLGVIYDDSDKVLKWYDETYLTYNNWRLGRPIIKKNSFFAGVNLDGFWDIYNYSQSWQAHHYNVYSILACKIERGPQQHKPPLPEFIPHGDVTYRILQKKLTWYDAVRECKQNMSDLASVHSESQQLFLEDIVKQDGYSLWLGLSIHDGSKANFEWSDGSSFDYYPWELENSNTTENCVLLDTKGSWNRAKCTNVAEGAICYSFSNKKQLEQKQVSRASGCSQLSGELPWIQYKDHCYAFDMAFYNFSVYNVEDAKKVCKKLNPSAALLTIGDAEENAFVSAHIKKNDLITRKVWLGLTQSSTGQTLHWLDGSSVNYANWDNRTTELSEKCSVITSTTGKWSKVDCSRSQSRVVCKAPLGSNHTGVAVAFALLVILVLVLGLVWFICKKKRLHWSAFSSVHYQRGLNDDEADDVFTKDGY", "length": 1732, "header": "tr|A0A8V0ZHS7-1|A0A8V0ZHS7_CHICK Isoform 1 of Lymphocyte antigen 75 OS=Gallus gallus OX=9031 GN=LY75 PE=1 SV=1 CANONICAL=A0A8V0ZHS7-1" }, "locus": { "chromosome": "7", "start_pos": 21544109, "end_pos": 21505583, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051158.1", "url": "https://www.ensembl.org/id/ENSGALT00010051158.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030349.1", "url": "https://www.ensembl.org/id/ENSGALP00010030349.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Expression of chicken DEC205 reflects the unique structure and function of the avian immune system.", "journal": "PloS one", "date": "2013", "authors": "Staines Karen, Young John R, Butter Colin", "evidence": [ { "database": "RefSeq", "id": "NP_001032925", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001032925" } ], "reference": [ { "type": "PubMed", "id": "23326318", "url": "https://glygen.org/publication/PubMed/23326318" } ] } ], "pathway": [ { "id": "gga:424192", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424192", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQK8-1", "protein_name": "Lymphocyte antigen 75", "gene_name": "Ly75", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTRWATPGRATGLLVLLLRCFELVEPSGNNPFTIVNENTGKCLQPLSDWIVAQDCSETKNMLWKWVSQHRLFHLESQKCLGLDITKATDNLRMFNCDSKAMLWWKCEHHSLYTAAQYSLALKDGYATASTNSTDVWKKGGSKENLCDQPYHEIYTRDGNSYGRPCEFPFLIGKTWHHDCIRDEDHKGPWCATTLNYEYDQKWGICLQPENGCEGNWEKNGQIGSCYQFNNQEVLTWKEAYVSCQNQGADLLSIHSTAELAYITGKEDIARIVWIGLNQLYSARGWEWSDFKPLKFLNWDPGMPIAPVIGGSSCARMDTESGLWQSVSCESQQPYICKKPLNSTAERPDDWTDSDTLCDGGWLPNKGFCYLLANESGSWDAARMKCKALGADLTSIHSLADVELVVTKLHSGDVKEEIWTGLKNTNSPTLFQWSDGTEVTVTHWNENEPNVPYNKTPNCVSYLGKLGQWKVQSCEKELRYVCKKKGEITKDARSDELCPPNEGWKRHGETCYKIYEKEVPFGTNCNLTITSRFEQEYLNDMMKNYDKSLQKYFWTGLRDADSRGEYSWAVAGGAKQAVTFSNWNFLEPASPGGCVAMSTGKTLGKWEVKNCRSFRALSICKKMRGPQASEEAAPKPDDPCPEGWHTFPSSLSCYKVFHIERIVRKRNWEEAERFCRALGAHLPSFSHRSEIKDLVHLLKDQFSGQRWLWIGLNKRSPDLQGSWQWSDRTPVSAVIMDWEFQQDYDIRDCAAVKVLDTPWHRAWHFYDEREYAYLKPFACDAKLEWVCQIPKGSTPQMPDWYNPERTGIHGPPVIIEGSEYWFVADPHLNYEEAVLYCASNQSFLATITSFTGLKAIKNKIANISGDDQKWWVKTSENPIDRYFLGSRRMWHRFPMTFGDECLHMSAKTWILDLSKRANCNAKLPFICEKYNVSSLEKYSPDPSAKVRCTGKWIPFQNKCFLKVNSEPVTFSQASSICHSYGGTLPSVLNRNEQDFIISLLPEMEASLWLGLRWSAYERINKWTDGQELTYSNFHPLLVGRRLSIPTNFFDDESHFHCALILNLKKSPLTGTWNFTSCSERHSLSLCQKYSETEDRQPWENTSETVRYLNNLYKIVSKPLTWHAALKECLTEGMRLVSITDPYQQAFLAVQAALRNTSFWIGLSSQDDELNFGWSDGKRLHFSNWAGSNEQLDDCVILDTDGFWKTADCDDSQPAAICYYPGNETEEEVRPLDSAKCPSPVQSTPWIPFQNACYNFMITKNRHKTVTPEEVQSMCKQLHSKAHSLSVRTEEENTFVVEQLLYYNYIASWVMLGITYENNSLMWFDKTALSYTHWRKGRPTVKNGKFLAGLSTDGFWDIQSFNIIEETLHFYQHSIFACKIEMVDYEDKHNSTLPQVIPYEDGVYNVIQKKVTWYEALKECSQSGGELASVHNPNGKLFLEDVVNRDGFPLWVGLSSHDGSESSFEWSDGSAFDYVPWNSPQSPGDCVVLYPKGIWRHERCPSVKDGAVCYKPTKPKELSSHTQSSKCPVAKREDVQWIQYGGHCYSSDQALHSFSEAKQLCQELDHSATVVTIADENENKFVSRLMRENFNITMRVWLGLSQHSLDQSWSWLDGLDVTFVKWENKSKDGDGKCSVLIASNETWRKVECSRGYARAVCKIPLSPDYRGIAILFAVLSVLALISGLIWFLLQRTHFHWTGFSPVRYEHGANEDEVMLPSFHD", "length": 1719 }, "evidence": [ { "id": "A0A8V0ZHS7", "url": "https://omabrowser.org/oma/group/A0A8V0ZHS7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60449-1", "protein_name": "Lymphocyte antigen 75", "gene_name": "LY75", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1722 }, "evidence": [ { "id": "A0A8V0ZHS7", "url": "https://omabrowser.org/oma/group/A0A8V0ZHS7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60767-1", "protein_name": "Lymphocyte antigen 75", "gene_name": "Ly75", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRTGRVTPGLAAGLLLLLLRSFGLVEPSESSGNDPFTIVHENTGKCIQPLSDWVVAQDCSGTNNMLWKWVSQHRLFHLESQKCLGLDITKATDNLRMFSCDSTVMLWWKCEHHSLYTAAQYRLALKDGYAVANTNTSDVWKKGGSEENLCAQPYHEIYTRDGNSYGRPCEFPFLIGETWYHDCIHDEDHSGPWCATTLSYEYDQKWGICLLPESGCEGNWEKNEQIGSCYQFNNQEILSWKEAYVSCQNQGADLLSIHSAAELAYITGKEDIARLVWLGLNQLYSARGWEWSDFRPLKFLNWDPGTPVAPVIGGSSCARMDTESGLWQSVSCESQQPYVCKKPLNNTLELPDVWTYTDTHCHVGWLPNNGFCYLLANESSSWDAAHLKCKAFGADLISMHSLADVEVVVTKLHNGDVKKEIWTGLKNTNSPALFQWSDGTEVTLTYWNENEPSVPFNKTPNCVSYLGKLGQWKVQSCEKKLRYVCKKKGEITKDAESDKLCPPDEGWKRHGETCYKIYEKEAPFGTNCNLTITSRFEQEFLNYMMKNYDKSLRKYFWTGLRDPDSRGEYSWAVAQGVKQAVTFSNWNFLEPASPGGCVAMSTGKTLGKWEVKNCRSFRALSICKKVSEPQEPEEAAPKPDDPCPEGWHTFPSSLSCYKVFHIERIVRKRNWEEAERFCQALGAHLPSFSRREEIKDFVHLLKDQFSGQRWLWIGLNKRSPDLQGSWQWSDRTPVSAVMMEPEFQQDFDIRDCAAIKVLDVPWRRVWHLYEDKDYAYWKPFACDAKLEWVCQIPKGSTPQMPDWYNPERTGIHGPPVIIEGSEYWFVADPHLNYEEAVLYCASNHSFLATITSFTGLKAIKNKLANISGEEQKWWVKTSENPIDRYFLGSRRRLWHHFPMTFGDECLHMSAKTWLVDLSKRADCNAKLPFICERYNVSSLEKYSPDPAAKVQCTEKWIPFQNKCFLKVNSGPVTFSQASGICHSYGGTLPSVLSRGEQDFIISLLPEMEASLWIGLRWTAYERINRWTDNRELTYSNFHPLLVGRRLSIPTNFFDDESHFHCALILNLKKSPLTGTWNFTSCSERHSLSLCQKYSETEDGQPWENTSKTVKYLNNLYKIISKPLTWHGALKECMKEKMRLVSITDPYQQAFLAVQATLRNSSFWIGLSSQDDELNFGWSDGKRLQFSNWAGSNEQLDDCVILDTDGFWKTADCDDNQPGAICYYPGNETEEEVRALDTAKCPSPVQSTPWIPFQNSCYNFMITNNRHKTVTPEEVQSTCEKLHSKAHSLSIRNEEENTFVVEQLLYFNYIASWVMLGITYENNSLMWFDKTALSYTHWRTGRPTVKNGKFLAGLSTDGFWDIQSFNVIEETLHFYQHSISACKIEMVDYEDKHNGTLPQFIPYKDGVYSVIQKKVTWYEALNACSQSGGELASVHNPNGKLFLEDIVNRDGFPLWVGLSSHDGSESSFEWSDGRAFDYVPWQSLQSPGDCVVLYPKGIWRREKCLSVKDGAICYKPTKDKKLIFHVKSSKCPVAKRDGPQWVQYGGHCYASDQVLHSFSEAKQVCQELDHSATVVTIADENENKFVSRLMRENYNITMRVWLGLSQHSLDQSWSWLDGLDVTFVKWENKTKDGDGKCSILIASNETWRKVHCSRGYARAVCKIPLSPDYTGIAILFAVLCLLGLISLAIWFLLQRSHIRWTGFSSVRYEHGTNEDEVMLPSFHD", "length": 1723 }, "evidence": [ { "id": "A0A8V0ZHS7", "url": "https://omabrowser.org/oma/group/A0A8V0ZHS7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "receptor-mediated endocytosis", "id": "GO:0006898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1075, "end_pos": 1077, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1099, "end_pos": 1101, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1106, "end_pos": 1108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1122, "end_pos": 1124, "annotation": 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"uniprot_canonical_ac": "A0A8V0ZHU2-1", "uniprot_ac": "A0A8V0ZHU2", "uniprot_id": "A0A8V0ZHU2_CHICK", "mass": { "chemical_mass": 79682.0, "monoisotopic_mass": 79682.0 }, "refseq": {}, "gene_names": [ { "name": "NHLRC2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2" } ] } ], "protein_names": [ { "name": "NHL repeat-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZHU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for normal embryonic development.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2#function" }, { "database": "UniProtKB", "id": "ARBA00057428", "url": "https://www.uniprot.org/uniprotkb/ARBA00057428#function" }, { "database": "UniProtKB", "id": "A0A8V0ZQG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NHLRC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2", "locus": { "chromosome": "6", "start_pos": 28394416, "end_pos": 28356602, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022400", "url": "https://www.ensembl.org/id/ENSGALG00010022400" } ] } } ], "crossref": [ { "id": "A0A8V0ZHU2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZHU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14951", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14951", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423903", "url": "https://www.ncbi.nlm.nih.gov/gene/423903", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423903", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423903", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IAMAGVH", "url": "https://omabrowser.org/oma/group/IAMAGVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHU2", "url": "https://www.orthodb.org/?gene=A0A8V0ZHU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQG7", "url": "https://www.orthodb.org/?gene=A0A8V0ZQG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVK1", "url": "https://www.orthodb.org/?gene=A0A8V0ZVK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46388:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46388:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01436", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01436", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13905", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13905", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEGLAGLLPAQTQLEYALLDADTPQEKENLVYQYLKKMDSRERDLTVPELSRDLQWLNTEGPISLHKDLCGKVVVLDFFTYCCINCLHLLPDLHELEHQYSDKDGLVIIGVHSAKFPNEKVLDSIKSAVLRYNIVHPVVNDADATLWHELEVSCWPTLVILGPRGNMLFSLVGEGHKEKLFLFTSITLKFYKERGQIKDNSIGIKLYKDSLPPSPLLFPGKVTVDKSGERLVIADTGHHRILVTLKNGQILHTIGGPNSGRKDGRFSEAAFNSPQGVAIKNNVIYVADTENHLIRKIDLELEIVTTVAGIGIQGVDKEGGAKGEEQPISSPWDVVFGNSVSGTQEDDVLWIAMAGIHQVWALMLEGGKLPKGSDLKKGVCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEEPWNCLFVADSESSTVRMISLKDGAVKHLVGGERDPLNLFAFGDVDGAGINAKLQHPLGITWDKKRKLLYVADSYNHKIKVVDPKMKNCATLAGTGEASNVVGSSFTQSTFNEPGGLCIEENGRLMYVADTNNHQIKVLDLETKILSMLPILNPETCDVTDNLSVQKDQIANLPKLPKSAPNIQLPSLSAAPGQTIQFLLKLTLPPDSKLNEEAPNAWFITAEDNNTWLLQGQCLSGEIKDVSCQTVIPFQLPRVCLSAEAVLAIKACLYYCSKDSSACMMKGISFNQPLQIGSTNQGGKMEIVLPSSRTSALL", "length": 729, "header": "tr|A0A8V0ZHU2-1|A0A8V0ZHU2_CHICK Isoform 1 of NHL repeat-containing protein 2 OS=Gallus gallus OX=9031 GN=NHLRC2 PE=1 SV=1 CANONICAL=A0A8V0ZHU2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2/entry#A0A8V0ZHU2-1", "sequence": { "sequence": "MAAEGLAGLLPAQTQLEYALLDADTPQEKENLVYQYLKKMDSRERDLTVPELSRDLQWLNTEGPISLHKDLCGKVVVLDFFTYCCINCLHLLPDLHELEHQYSDKDGLVIIGVHSAKFPNEKVLDSIKSAVLRYNIVHPVVNDADATLWHELEVSCWPTLVILGPRGNMLFSLVGEGHKEKLFLFTSITLKFYKERGQIKDNSIGIKLYKDSLPPSPLLFPGKVTVDKSGERLVIADTGHHRILVTLKNGQILHTIGGPNSGRKDGRFSEAAFNSPQGVAIKNNVIYVADTENHLIRKIDLELEIVTTVAGIGIQGVDKEGGAKGEEQPISSPWDVVFGNSVSGTQEDDVLWIAMAGIHQVWALMLEGGKLPKGSDLKKGVCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEEPWNCLFVADSESSTVRMISLKDGAVKHLVGGERDPLNLFAFGDVDGAGINAKLQHPLGITWDKKRKLLYVADSYNHKIKVVDPKMKNCATLAGTGEASNVVGSSFTQSTFNEPGGLCIEENGRLMYVADTNNHQIKVLDLETKILSMLPILNPETCDVTDNLSVQKDQIANLPKLPKSAPNIQLPSLSAAPGQTIQFLLKLTLPPDSKLNEEAPNAWFITAEDNNTWLLQGQCLSGEIKDVSCQTVIPFQLPRVCLSAEAVLAIKACLYYCSKDSSACMMKGISFNQPLQIGSTNQGGKMEIVLPSSRTSALL", "length": 729, "header": "tr|A0A8V0ZHU2-1|A0A8V0ZHU2_CHICK Isoform 1 of NHL repeat-containing protein 2 OS=Gallus gallus OX=9031 GN=NHLRC2 PE=1 SV=1 CANONICAL=A0A8V0ZHU2-1" }, "locus": { "chromosome": "6", "start_pos": 28394013, "end_pos": 28356818, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054460.1", "url": "https://www.ensembl.org/id/ENSGALT00010054460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032897.1", "url": "https://www.ensembl.org/id/ENSGALP00010032897.1" } ] } }, { "isoform_ac": "A0A8V0ZQG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2/entry#A0A8V0ZQG7-1", "sequence": { "sequence": "MAAEGLAGLLPAQTQLEYALLDADTPQEKENLVYQYLKKMDSRERDLTVPELSRDLQWLNTEGPISLHKDLCGKVVVLDFFTYCCINCLHLLPDLHELEHQYSDKDGLVIIGVHSAKFPNEKVLDSIKSAVLRYNIVHPVVNDADATLWHELEVSCWPTLVILGPRGNMLFSLVGEGHKEKLFLFTSITLKFYKERGQIKDNSIGIKLYKDSLPPSPLLFPGKVTVDKSGERLVIADTGHHRILVTLKNGQILHTIGGPNSGRKDGRFSEAAFNSPQGVAIKNNVIYVADTENHLIRKIDLELEIVTTVAGIGIQGVDKEGGAKGEEQPISSPWDVVFGNSVSGTQEDDVLWIAMAGIHQVWALMLEGGKLPKGSDLKKGVCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEEPWNCLFVADSESSTVRMISLKDGAVKHLVGGERDPLNLFAFGDVDGAGINAKLQHPLGITWDKKRKLLYVADSYNHKIKVVDPKMKNCATLAGTGEASNVVGSSFTQSTFNEPGGLCIEENGRLMYVADTNNHQIKVLDLETKILSMLPILNPETCDVTDNLSVQKDQIANLPKLPKSAPNIQLPSLSAAPGQTIQFLLKLTLPPDSKLNEEAPNAWFITAEDNNTWLLQGQCLSGEIKDVSCQTVIPFQLPRVCLSAEAVLAIKACLYYCSKDSSACMMKGISFNQPLQIGSTNQGRLTQVELTHSFITN", "length": 727, "header": "tr|A0A8V0ZQG7-1|A0A8V0ZQG7_CHICK Computationally mapped isoform of NHL repeat-containing protein 2 OS=Gallus gallus OX=9031 GN=NHLRC2 PE=1 SV=1 CANONICAL=A0A8V0ZHU2-1" }, "locus": { "chromosome": "6", "start_pos": 28387081, "end_pos": 28356818, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054457.1", "url": "https://www.ensembl.org/id/ENSGALT00010054457.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032895.1", "url": "https://www.ensembl.org/id/ENSGALP00010032895.1" } ] } }, { "isoform_ac": "A0A8V0ZVK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2/entry#A0A8V0ZVK1-1", "sequence": { "sequence": "MAAEGLAGLLPAQTQLEYALLDADTPQEKENLVYQYLKKMDSRERDLTVPELSRDGLVIIGVHSAKFPNEKVLDSIKSAVLRYNIVHPVVNDADATLWHELEVSCWPTLVILGPRGNMLFSLVGEGHKEKLFLFTSITLKFYKERGQIKDNSIGIKLYKDSLPPSPLLFPGKVTVDKSGERLVIADTGHHRILVTLKNGQILHTIGGPNSGRKDGRFSEAAFNSPQGVAIKNNVIYVADTENHLIRKIDLELEIVTTVAGIGIQGVDKEGGAKGEEQPISSPWDVVFGNSVSGTQEDDVLWIAMAGIHQVWALMLEGGKLPKGSDLKKGVCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEEPWNCLFVADSESSTVRMISLKDGAVKHLVGGERDPLNLFAFGDVDGAGINAKLQHPLGITWDKKRKLLYVADSYNHKIKVVDPKMKNCATLAGTGEASNVVGSSFTQSTFNEPGGLCIEENGRLMYVADTNNHQIKVLDLETKILSMLPILNPETCDVTDNLSVQKDQIANLPKLPKSAPNIQLPSLSAAPGQTIQFLLKLTLPPDSKLNEEAPNAWFITAEDNNTWLLQGQCLSGEIKDVSCQTVIPFQLPRVCLSAEAVLAIKACLYYCSKDSSACMMKGISFNQPLQIGSTNQGRLTQVELTHSFITN", "length": 676, "header": "tr|A0A8V0ZVK1-1|A0A8V0ZHU2_CHICK Computationally mapped isoform of NHL repeat-containing protein 2 OS=Gallus gallus OX=9031 GN=NHLRC2 PE=1 SV=1 CANONICAL=A0A8V0ZHU2-1" }, "locus": { "chromosome": "6", "start_pos": 28387081, "end_pos": 28356818, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054453.1", "url": "https://www.ensembl.org/id/ENSGALT00010054453.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032893.1", "url": "https://www.ensembl.org/id/ENSGALP00010032893.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423903", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423903", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A4IF69-1", "protein_name": "NHL repeat-containing protein 2", "gene_name": "NHLRC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAPGARSCNLSGLLPAQTSLEYALLDAVTQEEKDGLVYQYLQKVDGWEQDLLVPEFPEGLEWLNTEEPISVYKDLCGKVVILDFFTYCCINCIHLLPDLHALEHTYSDKDGLLIVGVHSAKFPNEKVLDNIRSAVLRYNITHPVVNDADASLWQELEVSCWPTLIILGPRGNMLFSLIGEGHKEKLFLYTSIALKYYKDRGQIRANKIGIKLYKDSLPPSPLLFPGKITVDHVSNRLVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESSFNSPQGVAIMNNIIYVADTENHLIRKIDLEAEMVSTVAGIGIQGTDKEGGAKGDEQPISSPWDVVFGRSGPEVQRDNILWIAMAGTHQIWALLLDCGRLPKKNELKKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEGPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINARLQHPLGVTWDQKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGNASNMIGSSFTDSTFNEPGGLCIGENGQLLYVADTNNHQIKVLDLETKTVSVFPVFRSENAVVDGPCLAGKPKTLPKLPKSAPGIRLAPVAASPGQTLQFKLRLDLPSGTKLTEGASSCWFLSAEGNEWLLQGQIPSGEIESISNQPTISLQIPGDCLSLEAILSISVFLYYCSSDSSACMMKGILFSQPLQITDTQQDCIPPVELKYIF", "length": 726 }, "evidence": [ { "id": "A0A8V0ZHU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZHU2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZLM5-1", "protein_name": "NHL repeat-containing protein 2", "gene_name": "Nhlrc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVPGARGASLSGLLPAQTSLEYALLDAVTQQEKDDLVYQYLQKVDGWEQDLAVPEFPEGLEWLNTEEPLSIYRDLCGKVVILDFFTYCCINCIHVLPDLHALERTFSDTDGLLIVGVHSAKFPNEKVLDNIKSAVLRYNITHPVVNDTDASLWQELEVSCWPTLVILGPRGNLLFSLIGEGHKDKLFSYTSIALKYYKDRGQIRDGKIGIKLFKESLPPSPLLFPGKVAADPTTGRLVVADTGHHRILVLQKNGQIQYSIGGPNPGRKDGVFSESSFHSPQGVAIADNVIYVADTENHLIRKIDLEAEKVSTVAGIGVQGTDTEGGEEGDKQPISSPWDVALGTSGSKVQRNDILWIAMAGTHQIWAFLLDSGTLPKKSDLKKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLALAPEEPWSCLFVADSESSTVRTVSLRDGAVKHLVGGERDPMNLFAFGDVDGAGISAKLQHPLGVAWDEKRHLLYVADSYNHKIKVVDPNTKVCTTLAGTGDANDASSSFAESAFNEPGGLCIGERGRLLYVADTNNHQIKVMDLEARTVSVLPVFKSDSAVVDGSFPREKQKTVPKVPKSAPNISLPPVTVHPGQALQLGLRLELPPGAKLTEGAPSGWFLKAEGNEWLLQEQIPSGDIENISNQPAISLQIPTECLSLEAVVSVTVFLYYCSADSSACMMKGVVFRQPLQINSVQPACAAPVELTYAF", "length": 725 }, "evidence": [ { "id": "A0A8V0ZHU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZHU2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S5H7-1", "protein_name": "NHL repeat-containing protein 2", "gene_name": "NHLRC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAPGARSCSLSGLLPAQTSLEYALLDAVTQEEKDSLVYQYLQKVDGWEQDLSVPEFPEGLEWLNTEESISIYKDLCGKVVVLDFFTYCCINCIHLLPDLHALEHTYSDKDGLLIVGVHSAKFPNEKVLDNIKSAVLRYNITHPVVNDAEASLWQELEVSCWPTLVILGPRGNMLFSLIGEGHKDKLFLYTSIALKYYKDRGQIKDNKIGIKLYKDSLTPSPLLFPGKVTVDHVTNRLVIADTGHHRILVVWKNGQIQYTIGGPNPGRKDGIFSESTFNSPQGVAIRNNIIYVADTENHLIRKIDLEAEMVSTVAGIGIQGTDKEGGANGEEQPISSPWDVVFGRSGSEAPGDDILWIAMAGTHQIWALLLDCGRLPKKNELKKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLSVASEDPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAKLQHPLGVTWDEKRNLLYVADSYNHKIKVVDPKTKSCTTLAGTGDAGDTIGSSFTKSTFNEPGGLCIGENGQLLYVADTNNHQIKVMDLETKTVSVLPVFRSESAMVDGPILAEKRTLPKLPKSAPGIRLSPVAASPGQTLQFKLRLDLPSGTKLTEGAPSCWFLSAEGNEWLLQGQIPSGEIESISNQPTISLQIPGDCVSLEVVLSISVFLYYCSTDSSACMMKGILFSQPLQITNTQQSYIAPVELKYIF", "length": 725 }, "evidence": [ { "id": "A0A8V0ZHU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZHU2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BZW8-1", "protein_name": "NHL repeat-containing protein 2", "gene_name": "Nhlrc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPGARGASLSGLLPAQTSLEYALLDAVTQQEKDELVYQYLQKVDGWEQDLAVPEFPEGLEWLNTEEPLSIYKDLCGKVVVLDFFTYCCINCIHVLPDLHALERRFSDKDGLLIVGVHSAKFPNEKVLDNIKSAVLRYNITHPVVNDADASLWQELEVSCWPTLVILGPRGNLLFSLIGEGHRDKLFSYTSIALKYYKDRGQIRDGKIGIKLFKESLPPSPLLFPGKVAVDHATGRLVVADTGHHRILVIQKNGRIQSSIGGPNPGRKDGMFSESSFNSPQGVAIADNVIYVADTENHLIRKIDLEAEKVTTVAGVGIQGTDTEGGEEGDKQPISSPWDVALGTSGSEVQRNDILWIAMAGTHQIWALLLDSGTLPKKSDLKKGTCIRFAGSGNEENRNNAYPHKAGFAQPSGLALASEEPWSCLFVADSESSTVRTVSLRDGAVKHLVGGERDPMNLFAFGDVDGAGINAKLQHPLGVAWDEERQVLYVADSYNHKIKVVDPKTKGCTTLAGTGDASDASSSFAESAFNEPGGLCIGESGRLLYVADTNNHQIKVMDLEARTVSVLPVCKSDSAVVDGSFPREKQKTVPKVPKSAAHIGLPPVTVHPGQALQLRLKLQLPPGAKLTEGAPSCWFLEAEGNEWLLQEQTPSGDIENISNQPAISLQIPTHCLSLEAVVSVVVFLYYCSADSSACMMKGVVFRQPLQITSTQPACAAPVELAYAF", "length": 725 }, "evidence": [ { "id": "A0A8V0ZHU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZHU2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NBF2-1", "protein_name": "NHL repeat-containing protein 2", "gene_name": "NHLRC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPGGRGRSLSGLLPAQTSLEYALLDAVTQQEKDSLVYQYLQKVDGWEQDLSVPEFPEGLEWLNTEEPISVYKDLCGKIVVLDFFTYCCINCIHLLPDLHALEHTYSDKDGLLIIGVHSAKFPNEKVLDNIKSAVLRYNITHPMVNDADASLWQELEVSCWPTLVILGPRGNMLFSLIGEGHKDKLFLYTSIALKYYKDRGQIRDNKIGIKLYKDSLPPSPLLFPGKVTVDQVTDRLVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESTFNSPQGVAIMNNIIYVADTENHLIRKIDLEAEKVSTVAGIGIQGTDKEGGAKGEQQPISSPWDVVFGTSGSEVQRGDILWIAMAGTHQIWALLLDSGKLPKKNELTKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEDPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAKLQHPLGVTWDKKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNEPGGLCIGENGELLYVADTNNHQIKVMDLETKMVSVLPIFRSENAVVDGPFLVEKQKTLPKLPKSAPSIRLSPVTACAGQTLQFKLRLDLPSGSKLTEGVSSCWFLTAEGNEWLLQGQIAAGDIENISSQPTISLQIPDDCLSLEAIVSVSVFLYYCSADSSACMMKAILFSQPLQITDTQQGCIAPVELRYVF", "length": 726 }, "evidence": [ { "id": "A0A8V0ZHU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZHU2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 640, "end_pos": 642, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZHU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU2" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"https://www.ebi.ac.uk/interpro/entry/IPR030113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHY8", "url": "https://www.orthodb.org/?gene=A0A8V0ZHY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHZ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZHZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQP2", "url": "https://www.orthodb.org/?gene=A0A8V0ZQP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14338", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14338", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14338:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14338:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKYKALEQLLTELEDFLRILDKENLSSTALVKKSFLSDLLRVYTKSSGTGGDEEYIYMNKVTVNRQQGDQEKQDKALDGKNSLTNGDLGLHSSPPQKSLPELPPPKEQTCSSACPAERSGVLALHALNILSRICTGLNQEPVEVIPETKQPSVPKIESPEGYYEEAEPYDVSMNDGEAVSSSYESYDEEESSKGKSATHQWPSTEATIELMKDARICAFLWRKKWLGQWAKQLCVIKDTRLLCYKSSKDHSPQLDVNLLGCTVIHKEKQVRKKEHKLKIIPMNADVIVLGLQSKDQAEQWLRVIQETSGLQCEGGSEGNQYIPDSQRLNYPKMDLSERYSAASESGSSTDGHPEAVETKDVKKKGTTGLKLSNLMNLGRKKSSSLDSPERSLETSSYLNVLVNSQWKSRWCQIKDGHLHFYQDKNRSKLAQQPLSLAGCEVIPEPSPDHLYSFRILHNGEERVVLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSFFLMQRKYSEPNAYIDNLPKGRVQQEELYDDVDLPDVPAEEVPKSESKLEGDQDRVYLDLTPVKSFLHCAGKKPCQPSSLSSPALERAGNKAAADSTAETAPVDKDAEPCKKEETSEQKHPEKLEPEEPPAQVPTVKIQTQQQNITFPQTAPEPPAGSVPVGSPQLVPAHRPKMPLPVAAVETKLGKNRTEAEVKRFTEEKERLEKEKDEIRAQLTQLRKERRELKEMLAGCTDKNLEQRLKEIDEECKKKESRRVDLELSLVEVKENLKKAESGPVTLGTTVDTTHLENTAPRTQTKPASPATSAESSPVNSATALKNRPLSVMVTGKGTVLQKAKEWEKKGAS", "length": 859, "header": "tr|A0A8V0ZHZ4-1|A0A8V0ZHZ4_CHICK Isoform 1 of Actin filament-associated protein 1-like 2 OS=Gallus gallus OX=9031 GN=AFAP1L2 PE=4 SV=1 CANONICAL=A0A8V0ZHZ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4/entry#A0A8V0ZHY8-1", "sequence": { "sequence": "MWMLSSQCREIRTELGTWNRKAGSLIDNPALEQLLTELEDFLRILDKENLSSTALVKKSFLSDLLRVYTKSSGGDEEYIYMNKVTVNRQQGDQEKQDKALDGKNSLTNGDLGLHSSPPQKSLPELPPPKIPETKQPSVPKIESPEGYYEEAEPYDVSMNEDGEAVSSSYESYDEEESSKGKSATHQWPSTEATIELMKDARICAFLWRKKWLGQWAKQLCVIKDTRLLCYKSSKDHSPQLDVNLLGCTVIHKEKQVRKKEHKLKIIPMNADVIVLGLQSKDQAEQWLRVIQETSGLQCEGGSEGNQYIPDSQRLNYPKMDLSERYSAASESGSSTDGHPEAVETKDVKKKGTTGLKLSNLMNLGRKKSSSLDSPERSLETSSYLNVLVNSQWKSRWCQIKDGHLHFYQDKNRSKLAQQPLSLAGCEVIPEPSPDHLYSFRILHNGEERVVLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSFFLMQRKYSEPNAYIDNLPKGRVQQEELYDDVDLPDVPAEEVPKSESKLEGDQDRVYLDLTPVKSFLHCAGKKPCQPSSLSSPALERAGNKAAADSTAETAPVDKDAEPCKKEETSEQKHPEKLEPEEPPAQVPTVKIQTQQQNITFPQTAPEPPAGSVPVGSPQLVPAHRPKMPLPVAAVETKLGKNRTEAEVKRFTEEKERLEKEKDEIRAQLTQLRKERRELKEMLAGCTDKNLEQRLKEIDEECKKKESRRVDLELSLVEVKENLKKAESGPVTLGTTVDTTHLENTAPRTQTKPASPATSAESSPVNSATALKNRPLSVMVTGKGTVLQKAKEWEKKGAS", "length": 844, "header": "tr|A0A8V0ZHY8-1|A0A8V0ZHZ4_CHICK Computationally mapped isoform of Actin filament-associated protein 1-like 2 OS=Gallus gallus OX=9031 GN=AFAP1L2 PE=4 SV=1 CANONICAL=A0A8V0ZHZ4-1" }, "locus": { "chromosome": "6", "start_pos": 28564308, "end_pos": 28542914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054541.1", "url": "https://www.ensembl.org/id/ENSGALT00010054541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032947.1", "url": "https://www.ensembl.org/id/ENSGALP00010032947.1" } ] } }, { "isoform_ac": "A0A8V0ZHZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4/entry#A0A8V0ZHZ4-1", "sequence": { "sequence": "MEKYKALEQLLTELEDFLRILDKENLSSTALVKKSFLSDLLRVYTKSSGTGGDEEYIYMNKVTVNRQQGDQEKQDKALDGKNSLTNGDLGLHSSPPQKSLPELPPPKEQTCSSACPAERSGVLALHALNILSRICTGLNQEPVEVIPETKQPSVPKIESPEGYYEEAEPYDVSMNDGEAVSSSYESYDEEESSKGKSATHQWPSTEATIELMKDARICAFLWRKKWLGQWAKQLCVIKDTRLLCYKSSKDHSPQLDVNLLGCTVIHKEKQVRKKEHKLKIIPMNADVIVLGLQSKDQAEQWLRVIQETSGLQCEGGSEGNQYIPDSQRLNYPKMDLSERYSAASESGSSTDGHPEAVETKDVKKKGTTGLKLSNLMNLGRKKSSSLDSPERSLETSSYLNVLVNSQWKSRWCQIKDGHLHFYQDKNRSKLAQQPLSLAGCEVIPEPSPDHLYSFRILHNGEERVVLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSFFLMQRKYSEPNAYIDNLPKGRVQQEELYDDVDLPDVPAEEVPKSESKLEGDQDRVYLDLTPVKSFLHCAGKKPCQPSSLSSPALERAGNKAAADSTAETAPVDKDAEPCKKEETSEQKHPEKLEPEEPPAQVPTVKIQTQQQNITFPQTAPEPPAGSVPVGSPQLVPAHRPKMPLPVAAVETKLGKNRTEAEVKRFTEEKERLEKEKDEIRAQLTQLRKERRELKEMLAGCTDKNLEQRLKEIDEECKKKESRRVDLELSLVEVKENLKKAESGPVTLGTTVDTTHLENTAPRTQTKPASPATSAESSPVNSATALKNRPLSVMVTGKGTVLQKAKEWEKKGAS", "length": 859, "header": "tr|A0A8V0ZHZ4-1|A0A8V0ZHZ4_CHICK Isoform 1 of Actin filament-associated protein 1-like 2 OS=Gallus gallus OX=9031 GN=AFAP1L2 PE=4 SV=1 CANONICAL=A0A8V0ZHZ4-1" }, "locus": { "chromosome": "6", "start_pos": 28596577, "end_pos": 28542914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054546.1", "url": "https://www.ensembl.org/id/ENSGALT00010054546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032952.1", "url": "https://www.ensembl.org/id/ENSGALP00010032952.1" } ] } }, { "isoform_ac": "A0A8V0ZQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4/entry#A0A8V0ZQP2-1", "sequence": { "sequence": "MEKYKALEQLLTELEDFLRILDKENLSSTALVKKSFLSDLLRVYTKSSGGDEEYIYMNKVTVNRQQGDQEKQDKALDGKNSLTNGDLGLHSSPPQKSLPELPPPKIPETKQPSVPKIESPEGYYEEAEPYDVSMNGLFGRLAAAGPRPGLQVTEAVIYATITMEDGEAVSSSYESYDEEESSKGKSATHQWPSTEATIELMKDARICAFLWRKKWLGQWAKQLCVIKDTRLLCYKSSKDHSPQLDVNLLGCTVIHKEKQVRKKEHKLKIIPMNADVIVLGLQSKDQAEQWLRVIQETSGLQCEGGSEGNQYIPDSQRLNYPKMDLSERYSAASESGSSTDGHPEAVETKDVKKKGTTGLKLSNLMNLGRKKSSSLDSPERSLETSSYLNVLVNSQWKSRWCQIKDGHLHFYQDKNRSKLAQQPLSLAGCEVIPEPSPDHLYSFRILHNGEERVVLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSFFLMQRKYSEPNAYIDNLPKGRVQQEELYDDVDLPDVPAEEVPKSESKLEGDQDRVYLDLTPVKSFLHCAGKKPCQPSSLSSPALERAGNKAAADSTAETAPVDKDAEPCKKEETSEQKHPEKLEPEEPPAQVPTVKIQTQQQNITFPQTAPEPPAGSVPVGSPQLVPAHRPKMPLPVAAVETKLGKNRTEAEVKRFTEEKERLEKEKDEIRAQLTQLRKERRELKEMLAGCTDKNLEQRLKEIDEECKKKESRRVDLELSLVEVKENLKKAESGPVTLGTTVDTTHLENTAPRTQTKPASPATSAESSPVNSATALKNRPLSVMVTGKGTVLQKAKEWEKKGAS", "length": 848, "header": "tr|A0A8V0ZQP2-1|A0A8V0ZQP2_CHICK Computationally mapped isoform of Actin filament-associated protein 1-like 2 OS=Gallus gallus OX=9031 GN=AFAP1L2 PE=4 SV=1 CANONICAL=A0A8V0ZHZ4-1" }, "locus": { "chromosome": "6", "start_pos": 28596577, "end_pos": 28542914, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054549.1", "url": "https://www.ensembl.org/id/ENSGALT00010054549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032955.1", "url": "https://www.ensembl.org/id/ENSGALP00010032955.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" } ], "pmid": "" }, { "name": "regulation of interleukin-6 production", "id": "GO:0032675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032675", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" } ], "pmid": "" }, { "name": "positive regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0045742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045742", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" } ], "pmid": "" }, { "name": "positive regulation of interleukin-8 production", "id": "GO:0032757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032757", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" } ], "pmid": "" }, { "name": "SH2 domain binding", "id": "GO:0042169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" } ], "pmid": "" }, { "name": "protein tyrosine kinase activator activity", "id": "GO:0030296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 658, "end_pos": 660, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZHZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHZ4" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 214, "end_pos": 310, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 658, "end_pos": 660 }, { "start_pos": 702, "end_pos": 704 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZI00-1", "uniprot_ac": "A0A8V0ZI00", "uniprot_id": "A0A8V0ZI00_CHICK", "mass": { "chemical_mass": 120220.0, "monoisotopic_mass": 120220.0 }, "refseq": {}, "gene_names": [ { "name": "STK11IP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein kinase 11-interacting protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STK11IP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00", "locus": { "chromosome": "7", "start_pos": 21672256, "end_pos": 21653740, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021152", "url": "https://www.ensembl.org/id/ENSGALG00010021152" } ] } } ], "crossref": [ { "id": "A0A8V0ZI00", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZI00", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI00", "url": "https://www.orthodb.org/?gene=A0A8V0ZI00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15454:SF69", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15454:SF69", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15904", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15904", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23142", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23142", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25624", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25624", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZI00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAEAAAEPLVSGLARLLQDTGDLVLDGSSTLTLLTPTLQHLTRVFEQHLGSRNQHRGFVALPSHPAETTAILQAQFLFDMLQKTHSLKLIHVPNCALQSTVKIFPFKSLRHLELRSVPPHCLRGLRFVYSQLESLTCSKCVSTLEEIISACGGDLSCALPWLELQTVNFSYNSITALDDSLQLLNALRVLDLSHNKVQDCEHYLTTLSELEYLNLAYNFLSKVPNLGIFSQSKLLTLILRNNELDSINGVEQLVNLQHLDVAYNLLLEHAQLAPLSTLHYLNKLHLEGNPLWFHQNHRSATLVHVSPRAASSNFLLDGEPLSSSDLMHLPKLVPSVSQSIHTSTSEKTILDRNALDSSCAADFSDSQSPAENVAVRLPRKKGKGKVKVRRASISEPSDTEHESQALPFSAGLVLQHQKEMERMDSFRDRFGVDWLQYKRLEEHDQVPVICRSRSADETTGRPAEVDLQSESFDPKQVKPQLSPKESSPAFHNAGAEEEPEVQPGEPPGGEQREEEADELMLGEEEDEKPEVDLCQPVLVSQIEGEGDPESDWIFLRVTARHVIEVELKAARVLHKLELKCLQKIETSEMTWKRMDLERVFPVLTLHFTYIRKDRQKRKYVVLDDCPEQCLQCVLEVLSPVVEENWRNQDQEKESLRLQCLKCKHEFLQSLAPWQQGPYPAETGDTKNLETLVALNQDASAAGEPIACPSCSSDHVVILPSEVSSSTPVPPSHDGTSEDLSDSALEGGSQQEGPEEVPALPRESGKFYIGGEDSLEMDTSNSTRTPELSGEHDSTIQSSSHSTDGGYGKKEQGMKSQYLSLSHRDTNGGSLMGSNRYSASRGPTSSQLSMTSDSEETWNLSPSANSALNKRDFRSVDHRLKLYLDMEVFEENDEEFQCFLKVTMVKFGRQGEFLSILVASNLRIYVLEVTGVIRGQPADWLKKDDSHYLSDISHLEVGLCHQSLRMEFENPKASYNLLIRSQSCCDQFLQTLTYLMQELPSKHRSKVKEIPAVEMNPQHWLWPLLDSKNTDSAAAGGTCFFYLLAYLIQEYSAPKWTQFKLRPCCQIDRTN", "length": 1073, "header": "tr|A0A8V0ZI00-1|A0A8V0ZI00_CHICK Isoform 1 of Serine/threonine-protein kinase 11-interacting protein OS=Gallus gallus OX=9031 GN=STK11IP PE=3 SV=1 CANONICAL=A0A8V0ZI00-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZI00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00/entry#A0A8V0ZI00-1", "sequence": { "sequence": "MAAAAEAAAEPLVSGLARLLQDTGDLVLDGSSTLTLLTPTLQHLTRVFEQHLGSRNQHRGFVALPSHPAETTAILQAQFLFDMLQKTHSLKLIHVPNCALQSTVKIFPFKSLRHLELRSVPPHCLRGLRFVYSQLESLTCSKCVSTLEEIISACGGDLSCALPWLELQTVNFSYNSITALDDSLQLLNALRVLDLSHNKVQDCEHYLTTLSELEYLNLAYNFLSKVPNLGIFSQSKLLTLILRNNELDSINGVEQLVNLQHLDVAYNLLLEHAQLAPLSTLHYLNKLHLEGNPLWFHQNHRSATLVHVSPRAASSNFLLDGEPLSSSDLMHLPKLVPSVSQSIHTSTSEKTILDRNALDSSCAADFSDSQSPAENVAVRLPRKKGKGKVKVRRASISEPSDTEHESQALPFSAGLVLQHQKEMERMDSFRDRFGVDWLQYKRLEEHDQVPVICRSRSADETTGRPAEVDLQSESFDPKQVKPQLSPKESSPAFHNAGAEEEPEVQPGEPPGGEQREEEADELMLGEEEDEKPEVDLCQPVLVSQIEGEGDPESDWIFLRVTARHVIEVELKAARVLHKLELKCLQKIETSEMTWKRMDLERVFPVLTLHFTYIRKDRQKRKYVVLDDCPEQCLQCVLEVLSPVVEENWRNQDQEKESLRLQCLKCKHEFLQSLAPWQQGPYPAETGDTKNLETLVALNQDASAAGEPIACPSCSSDHVVILPSEVSSSTPVPPSHDGTSEDLSDSALEGGSQQEGPEEVPALPRESGKFYIGGEDSLEMDTSNSTRTPELSGEHDSTIQSSSHSTDGGYGKKEQGMKSQYLSLSHRDTNGGSLMGSNRYSASRGPTSSQLSMTSDSEETWNLSPSANSALNKRDFRSVDHRLKLYLDMEVFEENDEEFQCFLKVTMVKFGRQGEFLSILVASNLRIYVLEVTGVIRGQPADWLKKDDSHYLSDISHLEVGLCHQSLRMEFENPKASYNLLIRSQSCCDQFLQTLTYLMQELPSKHRSKVKEIPAVEMNPQHWLWPLLDSKNTDSAAAGGTCFFYLLAYLIQEYSAPKWTQFKLRPCCQIDRTN", "length": 1073, "header": "tr|A0A8V0ZI00-1|A0A8V0ZI00_CHICK Isoform 1 of Serine/threonine-protein kinase 11-interacting protein OS=Gallus gallus OX=9031 GN=STK11IP PE=3 SV=1 CANONICAL=A0A8V0ZI00-1" }, "locus": { "chromosome": "7", "start_pos": 21670074, "end_pos": 21653880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051230.1", "url": "https://www.ensembl.org/id/ENSGALT00010051230.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030421.1", "url": "https://www.ensembl.org/id/ENSGALP00010030421.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 846, "start_aa": "Thr", "end_pos": 846, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr846", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 783, "end_pos": 785, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZI00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00" }, { "id": "PF15904", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LKB1 serine/threonine kinase interacting protein 1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 96, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZI00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00" }, { "id": "PF23142", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23142" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLEKHM2 PH", "eco_id": "ECO_0000259", "start_pos": 870, "end_pos": 1010, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZI00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00" }, { "id": "PF25624", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25624" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "STK11-interacting protein C-terminal PH", "eco_id": "ECO_0000259", "start_pos": 1017, "end_pos": 1055, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZI00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI00" }, { "id": "PF25357", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25357" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serine/threonine-protein kinase 11-interacting protein PH", "eco_id": "ECO_0000259", "start_pos": 531, "end_pos": 647, "start_aa": "Lys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 846 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 783, "end_pos": 785 }, { "start_pos": 861, "end_pos": 863 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZI47-1", "uniprot_ac": "A0A8V0ZI47", "uniprot_id": "A0A8V0ZI47_CHICK", "mass": { "chemical_mass": 70319.0, "monoisotopic_mass": 70319.0 }, "refseq": { "ac": "XP_003641693", "name": "beta-galactosidase-1-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641693" }, "gene_names": [ { "name": "GLB1L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47" } ] }, { "name": "GLB1L", "type": "synonym", "evidence": [ { "id": "XP_003641693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641693" } ] } ], "protein_names": [ { "name": "beta-galactosidase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.23", "type": "synonym", "evidence": [ { "id": "A0A8V0ZI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47/entry#names_and_taxonomy" } ] }, { "name": "beta-galactosidase-1-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003641693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641693" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003641693.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641693" } ] }, { "annotation": "Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47#function" }, { "database": "UniProtKB", "id": "ARBA00002691", "url": "https://www.uniprot.org/uniprotkb/ARBA00002691#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLB1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47", "locus": { "chromosome": "7", "start_pos": 21839591, "end_pos": 21835425, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021421", "url": "https://www.ensembl.org/id/ENSGALG00010021421" } ] } } ], "crossref": [ { "id": "A0A8V0ZI47", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZI47", "database": "AlphaFoldDB", "categories": [] }, { "id": "429037", "url": "https://www.ncbi.nlm.nih.gov/gene/429037", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429037", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429037", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HERQYLH", "url": "https://omabrowser.org/oma/group/HERQYLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI47", "url": "https://www.orthodb.org/?gene=A0A8V0ZI47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23421", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23421", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01301", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01301", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022857", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022857", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2024101", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024101", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9840310", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003641693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641693", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLPALGLLLAAALLRTEAAPPARSFQIDFERDCFRKDGAPFRYVSGSVHYARVPRPAWRDRLLRLYMAGLNAVQVYVPWNYHEPQPGVYDFSGDRDVEAFLDLAAELGLLVILRPGPYICAEWEMGGLPAWLLWKADIILRSSDPAYLAAVDAWLHVLLPKIKPRLYQHGGNIISVQVENEYGSYYACDLGYLQHLLGTFRALLGPEVLLFTTDGAQVEELHCGTLRGLYATIDFGPDSNVTEAFDAQRHVEPMGPLVNSEYYTGWLDYWGGPHASTSATLVAQGLADMLQLGANVNMYMFHGGTNFAYWSGADFKDQYKPVTTSYDYDAPLSEAGDPTEKLFAIRTVISKFQPLPVGPMPPPTPKYAYGRVALHKYADLLDVLDVLSPSGPIQRQFPLIFEAVKQAHGFMLYRTQLPYDILAPATLSAPPHSICDRGYVMLQKEYQGTLERDGQTELRVKGKAGDTLDVLLENMGRISFGANFSDFKGLLGNLSLDSRPLSKWLIYPLAIDAAIQQGWPHAALPKSSCRGRAGPAFYTGTFETPGIAWDTFVKFPGWSKGQLWINGFNLGRYWPRQGPQQTLFVPGSILRVGCPNNITVLELEEAPPNPFLLFLDQPLFNTTLSHSSPDKE", "length": 633, "header": "tr|A0A8V0ZI47-1|A0A8V0ZI47_CHICK Isoform 1 of beta-galactosidase OS=Gallus gallus OX=9031 GN=GLB1L PE=1 SV=1 CANONICAL=A0A8V0ZI47-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZI47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47/entry#A0A8V0ZI47-1", "sequence": { "sequence": "MGLPALGLLLAAALLRTEAAPPARSFQIDFERDCFRKDGAPFRYVSGSVHYARVPRPAWRDRLLRLYMAGLNAVQVYVPWNYHEPQPGVYDFSGDRDVEAFLDLAAELGLLVILRPGPYICAEWEMGGLPAWLLWKADIILRSSDPAYLAAVDAWLHVLLPKIKPRLYQHGGNIISVQVENEYGSYYACDLGYLQHLLGTFRALLGPEVLLFTTDGAQVEELHCGTLRGLYATIDFGPDSNVTEAFDAQRHVEPMGPLVNSEYYTGWLDYWGGPHASTSATLVAQGLADMLQLGANVNMYMFHGGTNFAYWSGADFKDQYKPVTTSYDYDAPLSEAGDPTEKLFAIRTVISKFQPLPVGPMPPPTPKYAYGRVALHKYADLLDVLDVLSPSGPIQRQFPLIFEAVKQAHGFMLYRTQLPYDILAPATLSAPPHSICDRGYVMLQKEYQGTLERDGQTELRVKGKAGDTLDVLLENMGRISFGANFSDFKGLLGNLSLDSRPLSKWLIYPLAIDAAIQQGWPHAALPKSSCRGRAGPAFYTGTFETPGIAWDTFVKFPGWSKGQLWINGFNLGRYWPRQGPQQTLFVPGSILRVGCPNNITVLELEEAPPNPFLLFLDQPLFNTTLSHSSPDKE", "length": 633, "header": "tr|A0A8V0ZI47-1|A0A8V0ZI47_CHICK Isoform 1 of beta-galactosidase OS=Gallus gallus OX=9031 GN=GLB1L PE=1 SV=1 CANONICAL=A0A8V0ZI47-1" }, "locus": { "chromosome": "7", "start_pos": 21839573, "end_pos": 21835541, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051928.1", "url": "https://www.ensembl.org/id/ENSGALT00010051928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030989.1", "url": "https://www.ensembl.org/id/ENSGALP00010030989.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 365, "start_aa": "Thr", "end_pos": 365, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr365", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:429037", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429037", "resource": "KEGG Pathway" }, { "id": "R-GGA-2022857", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022857", "resource": "Reactome", "description": "Keratan sulfate degradation" }, { "id": "R-GGA-2024101", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024101", "resource": "Reactome", "description": "CS/DS degradation" }, { "id": "R-GGA-9840310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840310", "resource": "Reactome", "description": "Glycosphingolipid catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "B1WBS6-1", "protein_name": "beta-galactosidase", "gene_name": "Glb1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPDLPSLLLRLVILLLLSQAEARSFVVDRQHDRFLLDGVPFRYISGSLHYFRVPRVLWADRLLKMKLSGLNAVQFYVPWNYHEPEPGIYNFNGSRDLTAFLNEAAKANLLVILRPGPYICAEWEMGGLPSWLLRNRDIHLRTSDPAFLHAVDSWFKVLLPKIYPFLYHNGGNIISIQVENEYGSYKVCDFKYMRHLAGLFRALLGDEILLFTTDGPQGLRCGSLQGLYATVDFGPADNVTRIFSLLREYEPHGPLVNSEYYTGWLDYWGQNHSTRSTPAVARGLERILKLGASVNMYMFHGGTNFGYWNGADDKGYFLPITTSYDYDAPISEAGDPTPKLFAIQNVISKFQEIPLGPLPPPSPKMKLGPLTMSLDGNLLSFLDFLCPEGPIHSVLPLTFEAVKLDRGFMLYRTYMTYTVSEPTPLWVPNNGIHDRAYVMVDGVLKGILERSLKEELYLTGKVGTRLDILLENMGRLSFGSNHSDFKGLLEPPLLGQTVLTGWMMFPLKVDKLVKWWIPLQLMKRAQPQAPSVPAFYSAKFPALGLLGDTFLYLPGWTKGQVWINGFNLGRYWTMRGPQQTLYVPRPLLFGSSINKITLLELEDVPHDPQIQFLDKPILNSTLHWGYNYLLSEPQGSYEPIELSGH", "length": 646 }, "evidence": [ { "id": "A0A8V0ZI47", "url": "https://omabrowser.org/oma/group/A0A8V0ZI47/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BCP9-1", "protein_name": "beta-galactosidase", "gene_name": "GLB1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPKKPLCLPFLLLPLLTLLLPQADARSFVVDRDHNRFLLDGAPFRYVSGSLHYFRVPRVLWADRLLKMRMSGLNVVQFYVPWNYHEPEPGVYNFNGSRDLFAFLKEATLANLLVILRPGPYICAEWEMGGLPAWLLRKPKIHLRTSDPDFLAAVDSWFKVLLPRIYPWLYHNGGNIISIQVENEYGSYRACDVSYMRHLAGLFRALLGDRILLFTTDGPEGLKCGSLQGLYTTVDFGPADNMTKIFGLLRKYEPRGPLVNSEYYTGWLDYWGQNHSTRSIPAVTKGLEKMLKLGASVNMYMFHGGTNFGYWNGADEKGRFLPITTSYDYDAPISEAGDPTPKLFAIRNVISKFQEVPLGPLPPPSPKMTLGPLNLHLDGNLLDFLDFLCPQGPIHSVLPMTFEAVNQVHGYMLYRTYLPHTVSEPTQLWVPNNGVHDRAYVMVDGVFQGVLERNMKHNLFLMGKIGATLDVLLENMGRLSFGSNSSDFKGLLQPPILGQTILTQWLMFPLKVDNLVKGWFPIQPLKHSHPQTPSGPTFYSTTFPILNSGGDTFLFLPGWTKGQVWINGFNLGRYWTKRGPQQTLYVPRPLLFPRGAHNRITLLELENVPPQPQIQFLDRPILNSTKHRTYVYSLSSASEPMELSGH", "length": 647 }, "evidence": [ { "id": "A0A8V0ZI47", "url": "https://omabrowser.org/oma/group/A0A8V0ZI47/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6UWU2-1", "protein_name": "Beta-galactosidase-1-like protein", "gene_name": "GLB1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPKKLSCLRSLLLPLSLTLLLPQADTRSFVVDRGHDRFLLDGAPFRYVSGSLHYFRVPRVLWADRLLKMRWSGLNAIQFYVPWNYHEPQPGVYNFNGSRDLIAFLNEAALANLLVILRPGPYICAEWEMGGLPSWLLRKPEIHLRTSDPDFLAAVDSWFKVLLPKIYPWLYHNGGNIISIQVENEYGSYRACDFSYMRHLAGLFRALLGEKILLFTTDGPEGLKCGSLRGLYTTVDFGPADNMTKIFTLLRKYEPHGPLVNSEYYTGWLDYWGQNHSTRSVSAVTKGLENMLKLGASVNMYMFHGGTNFGYWNGADKKGRFLPITTSYDYDAPISEAGDPTPKLFALRDVISKFQEVPLGPLPPPSPKMMLGPVTLHLVGHLLAFLDLLCPRGPIHSILPMTFEAVKQDHGFMLYRTYMTHTIFEPTPFWVPNNGVHDRAYVMVDGVFQGVVERNMRDKLFLTGKLGSKLDILVENMGRLSFGSNSSDFKGLLKPPILGQTILTQWMMFPLKIDNLVKWWFPLQLPKWPYPQAPSGPTFYSKTFPILGSVGDTFLYLPGWTKGQVWINGFNLGRYWTKQGPQQTLYVPRFLLFPRGALNKITLLELEDVPLQPQVQFLDKPILNSTSTLHRTHINSLSADTLSASEPMELSGH", "length": 654 }, "evidence": [ { "id": "A0A8V0ZI47", "url": "https://omabrowser.org/oma/group/A0A8V0ZI47/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VC60-1", "protein_name": "Beta-galactosidase-1-like protein", "gene_name": "Glb1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPDLPSLLLRLVVLLLLSQAEARSFVVDREHDRFLLDGVPFRYVSGSLHYFRVPPVLWADRLLKMQLSGLNAVQFYVPWNYHEPEPGIYNFNGSRDLIAFLNEAAKVNLLVILRPGPYICAEWEMGGLPSWLLRNPNIHLRTSDPAFLEAVDSWFKVLLPKIYPFLYHNGGNIISIQVENEYGSYKACDFKYMRHLAGLFRALLGDKILLFTTDGPHGLRCGSLQGLYTTIDFGPADNVTRIFSLLREYEPHGPLVNSEYYTGWLDYWGQNHSTRSSPAVAQGLEKMLKLGASVNMYMFHGGTNFGYWNGADEKGRFLPITTSYDYDAPISEAGDPTPKLFAIRNVISKFQEIPLGPLPPPSPKMKFGPLTMSLDGNLLSFLDFLCPQGPIHSVLPLTFEAVKLDHGFMLYRTYLTSPVLEPTPFWVPNNGIHDRAYVMVDGVLKGVLERSLKQELYLTGTVGTRLDILLENMGRLSFGSNHSDFKGLLEAPLLGQTILTEWMMFPLKVDKLVKWWFPLQLMKRALPQASSVPAFYSAKFPVFGLLGDTFLYLPGWTKGQVWINGFNLGRYWTMRGPQQTLYVPRLLLFGRSINKITLLELENVPHNPQVQFLDKPILNSTLHWGYNFLLSETQGSFEPMELSGH", "length": 646 }, "evidence": [ { "id": "A0A8V0ZI47", "url": "https://omabrowser.org/oma/group/A0A8V0ZI47/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "beta-galactosidase activity", "id": "GO:0004565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004565", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "galactose catabolic process", "id": "GO:0019388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019388", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1605624", "name": "Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal membrane, lysosomal lumen", "input_participant_list": [], "output_participant_list": [ "R-ALL-1605637" ], "enzyme_list": [ "A0A8V1A7L0-1", "A0A8V0Z0Z6-1", "A0A8V0ZI47-1" ], "evidence": [ { "id": "R-GGA-1605624", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1605624" } ] }, { "id": "R-GGA-1606312", "name": "GLB1 hydrolyzes SapB/C:LacCer", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A7L0-1", "A0A8V0Z0Z6-1", "A0A8V0ZI47-1" ], "evidence": [ { "id": "R-GGA-1606312", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1606312" } ] }, { "id": "R-GGA-1630306", "name": "GLB1 hydrolyses a glycosaminoglycan", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2104997" ], "output_participant_list": [], "enzyme_list": [ "A0A8V1A7L0-1", "A0A8V0Z0Z6-1", "A0A8V0ZI47-1" ], "evidence": [ { "id": "R-GGA-1630306", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1630306" } ] }, { "id": "R-GGA-2090079", "name": "GLB1 hydrolyses linker chain(2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2090075" ], "output_participant_list": [ "R-ALL-2090063" ], "enzyme_list": [ "A0A8V1A7L0-1", "A0A8V0Z0Z6-1", "A0A8V0ZI47-1" ], "evidence": [ { "id": "R-GGA-2090079", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2090079" } ] }, { "id": "R-GGA-9840795", "name": "Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. 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"https://www.ensembl.org/id/ENSGALG00010022472" } ] } } ], "crossref": [ { "id": "421599", "url": "https://www.ncbi.nlm.nih.gov/gene/421599", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052466", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052466", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI64", "url": "https://www.orthodb.org/?gene=A0A8V0ZI64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQC7", "url": "https://www.orthodb.org/?gene=A0A8V0ZQC7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQD3", "url": "https://www.orthodb.org/?gene=A0A8V0ZQD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQY5", "url": "https://www.orthodb.org/?gene=A0A8V0ZQY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQZ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZQZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVZ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZVZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZW01", "url": "https://www.orthodb.org/?gene=A0A8V0ZW01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZW07", "url": "https://www.orthodb.org/?gene=A0A8V0ZW07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14709", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14709", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14709:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14709:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZI64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNFQKLVDCSLACHLLVLLLTILVVVSFLYNCMVLLIMFNFFLSLSYGGGHPSHSETDLLHRQTYTASHQLPGYSATHHPTGLSGIFDTGMHTSGSNTKETSVMNFLSAIESRTAQAVSSGSTLLPQFRAPSWQTGMHSSTATELFVTGALPTSGTFPPTSALSAYQHPNTFSSRNFATTPSLTLQDTTFSATSNGLLTTHDPLLQIKTSQGTVPAALTFERLGSSVLSTSVPPQSSTYRSAQESAPHLLQPQFSLLPSTIGGAQQVSQAYSTSVFTGSTASIDRALQRECSVIKHHQRPSSTQSVQAQLTVSQHSLHSYLTSTSGVNFQDTCRHSALSCSPVGDVTQVSNGGPQQKTSQVTVELAQSYASAVPSSGFPPASAAKVKNCSTKQPPRSTKTPKPQSIAPPVQTQSYAKTAQNQSSVITGQAQIYSTAQLPSLLSVSQSQNYISSQAQNVPPVSHSQDFSSSKVEKLPTLYKTLTFSGQSQTITSDSQTLSYSSDEQVLTSVPNESYSPQTRELSSVSQSQSYSSSHSQGLSPVSQSQVSFSSQSQVLSAVSPSESYSSGQSLTLTSPSLPFSASPRIQTLPASSPNQSYISLHSSQNTQSQESSSPQSQKFLPSVQSPPFASPAHSQALQNSRPSSETKTYVKRKSDSNLYASSKQEEELSMQDMQALQRQASLESSTQRLTDEEINAQDASYRVTKADDRYSQSVIRSNSRLEDQVVGLTLQGTKKEERMANTVEQLSQHIGHITNLSHDMKKAANLMQSTQVNVSSKELNQQHSLIHKVHESKASEQQGQVISTTPQVQPHALRHGHQLCLPGAQVLLESTCDLQILHQSILQSGLGQAKASPQVQRIQSPQQVTHPFLQMDGHIIQSNGGHSQQQLHTQNSEVMKMDISEPSKPLQQHLTTKDHFTQTNQHDSKNPFVSLSSICFPESMLLSDERNILSNVDDILAATAAACGVTPSDFAKSASNEEEIRSVENSEESKTQFRSMDVRHVSAGFNASPAIVGKPASINNISLNGGQITINLTPVSAIQTKAVNLNHQHIDASDQNVPTRMTSPTLGPGQEEQEQGAVPVKKQSSISRESEEDNDVSADGTLNARDLDFVSSGKSLSEESAASENDFNMSGDDGTVASNQSKGPLQSLPVPQSGAEEECQDLSQGNLQKKKSKGKSQNKNAAEEDSAIQKQIKRSGQCKRQNSRGNDSCLMYSSPVSESCYDTYQHQERMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPRQQFSAPAVRMPNRTRRPVTQIVRGPCLQSPTKPVPAAAPAASDVTGESPTKKADEELKKNLETLPSFSSDEDDSVGGNHDLQKSISTALSALDDSSDRKNKSEAEKVAAVSAASTAAVIKQELPQTTSPVVNVQEKMSSADSLKAAQQDAGTSDQLAKIQATVAIEGSTEEENTDSGGEGMYRERDEFVVKIEDIETLKLALQTGKEPPAIWKVQKALLQKFVPEVRDGQREFAATNSYLGYFGDAKTKYKRVYVKFIENANKKEYVRVCSRKPRSKPVQSARTIHCKPSSSNNKTPDPPTPKPAAAKVSSVKPKAKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEAQSDEDELVPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMRKIDGMLNDNRKRLLSKLRLDNTFKSALEIFPELTVITRDSKTKSGGASVSKIKMNGKAYNKKTLRASKSTTKLAQEFTVDPEKIQLYSLYHSLHHYKYHIYLTCKEEISSVQKKSADLGQEEIVQLCMKNMKWVEDLFEKFGELLNRVQQKCS", "length": 1824, "header": "tr|A0A8V0ZI64-1|A0A8V0ZI64_CHICK Isoform 1 of Glutamine and serine rich 1 OS=Gallus gallus OX=9031 GN=QSER1 PE=4 SV=1 CANONICAL=A0A8V0ZI64-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZI64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI64/entry#A0A8V0ZI64-1", "sequence": { "sequence": "MPNFQKLVDCSLACHLLVLLLTILVVVSFLYNCMVLLIMFNFFLSLSYGGGHPSHSETDLLHRQTYTASHQLPGYSATHHPTGLSGIFDTGMHTSGSNTKETSVMNFLSAIESRTAQAVSSGSTLLPQFRAPSWQTGMHSSTATELFVTGALPTSGTFPPTSALSAYQHPNTFSSRNFATTPSLTLQDTTFSATSNGLLTTHDPLLQIKTSQGTVPAALTFERLGSSVLSTSVPPQSSTYRSAQESAPHLLQPQFSLLPSTIGGAQQVSQAYSTSVFTGSTASIDRALQRECSVIKHHQRPSSTQSVQAQLTVSQHSLHSYLTSTSGVNFQDTCRHSALSCSPVGDVTQVSNGGPQQKTSQVTVELAQSYASAVPSSGFPPASAAKVKNCSTKQPPRSTKTPKPQSIAPPVQTQSYAKTAQNQSSVITGQAQIYSTAQLPSLLSVSQSQNYISSQAQNVPPVSHSQDFSSSKVEKLPTLYKTLTFSGQSQTITSDSQTLSYSSDEQVLTSVPNESYSPQTRELSSVSQSQSYSSSHSQGLSPVSQSQVSFSSQSQVLSAVSPSESYSSGQSLTLTSPSLPFSASPRIQTLPASSPNQSYISLHSSQNTQSQESSSPQSQKFLPSVQSPPFASPAHSQALQNSRPSSETKTYVKRKSDSNLYASSKQEEELSMQDMQALQRQASLESSTQRLTDEEINAQDASYRVTKADDRYSQSVIRSNSRLEDQVVGLTLQGTKKEERMANTVEQLSQHIGHITNLSHDMKKAANLMQSTQVNVSSKELNQQHSLIHKVHESKASEQQGQVISTTPQVQPHALRHGHQLCLPGAQVLLESTCDLQILHQSILQSGLGQAKASPQVQRIQSPQQVTHPFLQMDGHIIQSNGGHSQQQLHTQNSEVMKMDISEPSKPLQQHLTTKDHFTQTNQHDSKNPFVSLSSICFPESMLLSDERNILSNVDDILAATAAACGVTPSDFAKSASNEEEIRSVENSEESKTQFRSMDVRHVSAGFNASPAIVGKPASINNISLNGGQITINLTPVSAIQTKAVNLNHQHIDASDQNVPTRMTSPTLGPGQEEQEQGAVPVKKQSSISRESEEDNDVSADGTLNARDLDFVSSGKSLSEESAASENDFNMSGDDGTVASNQSKGPLQSLPVPQSGAEEECQDLSQGNLQKKKSKGKSQNKNAAEEDSAIQKQIKRSGQCKRQNSRGNDSCLMYSSPVSESCYDTYQHQERMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPRQQFSAPAVRMPNRTRRPVTQIVRGPCLQSPTKPVPAAAPAASDVTGESPTKKADEELKKNLETLPSFSSDEDDSVGGNHDLQKSISTALSALDDSSDRKNKSEAEKVAAVSAASTAAVIKQELPQTTSPVVNVQEKMSSADSLKAAQQDAGTSDQLAKIQATVAIEGSTEEENTDSGGEGMYRERDEFVVKIEDIETLKLALQTGKEPPAIWKVQKALLQKFVPEVRDGQREFAATNSYLGYFGDAKTKYKRVYVKFIENANKKEYVRVCSRKPRSKPVQSARTIHCKPSSSNNKTPDPPTPKPAAAKVSSVKPKAKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEAQSDEDELVPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMRKIDGMLNDNRKRLLSKLRLDNTFKSALEIFPELTVITRDSKTKSGGASVSKIKMNGKAYNKKTLRASKSTTKLAQEFTVDPEKIQLYSLYHSLHHYKYHIYLTCKEEISSVQKKSADLGQEEIVQLCMKNMKWVEDLFEKFGELLNRVQQKCS", "length": 1824, "header": "tr|A0A8V0ZI64-1|A0A8V0ZI64_CHICK Isoform 1 of Glutamine and serine rich 1 OS=Gallus gallus OX=9031 GN=QSER1 PE=4 SV=1 CANONICAL=A0A8V0ZI64-1" }, "locus": { "chromosome": "5", "start_pos": 5846634, "end_pos": 5826591, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054667.1", "url": "https://www.ensembl.org/id/ENSGALT00010054667.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033027.1", "url": "https://www.ensembl.org/id/ENSGALP00010033027.1" } ] } }, { "isoform_ac": "A0A8V0ZQC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI64/entry#A0A8V0ZQC7-1", "sequence": { "sequence": "MDLFNEHTSRGNCFSNVLSYGGGHPSHSETDLLHRQTYTASHQLPGYSATHHPTGLSGIFDTGMHTSGSNTKETSVMNFLSAIESRTAQAVSSGSTLLPQFRAPSWQTGMHSSTATELFVTGALPTSGTFPPTSALSAYQHPNTFSSRNFATTPSLTLQDTTFSATSNGLLTTHDPLLQIKTSQGTVPAALTFERLGSSVLSTSVPPQSSTYRSAQESAPHLLQPQFSLLPSTIGGAQQVSQAYSTSVFTGSTASIDRALQRECSVIKHHQRPSSTQSVQAQLTVSQHSLHSYLTSTSGVNFQDTCRHSALSCSPVGDVTQVSNGGPQQKTSQVTVELAQSYASAVPSSGFPPASAAKVKNCSTKQPPRSTKTPKPQSIAPPVQTQSYAKTAQNQSSVITGQAQIYSTAQLPSLLSVSQSQNYISSQAQNVPPVSHSQDFSSSKVEKLPTLYKTLTFSGQSQTITSDSQTLSYSSDEQVLTSVPNESYSPQTRELSSVSQSQSYSSSHSQGLSPVSQSQVSFSSQSQVLSAVSPSESYSSGQSLTLTSPSLPFSASPRIQTLPASSPNQSYISLHSSQNTQSQESSSPQSQKFLPSVQSPPFASPAHSQALQNSRPSSETKTYVKRKSDSNLYASSKQEEELSMQDMQALQRQASLESSTQRLTDEEINAQDASYRVTKADDRYSQSVIRSNSRLEDQVVGLTLQGTKKEERMANTVEQLSQHIGHITNLSHDMKKAANLMQSTQVNVSSKELNQQHSLIHKVHESKASEQQGQVISTTPQVQPHALRHGHQLCLPGAQVLLESTCDLQILHQSILQSGLGQAKASPQVQRIQSPQQVTHPFLQMDGHIIQSNGGHSQQQLHTQNSEVMKMDISEPSKPLQQHLTTKDHFTQTNQHDSKNPFVSLSSICFPESMLLSDERNILSNVDDILAATAAACGVTPSDFAKSASNEEEIRSVENSEESKTQFRSMDVRHVSAGFNASPAIVGKPASINNISLNGGQITINLTPVSAIQTKAVNLNHQHIDASDQNVPTRMTSPTLGPGQEEQEQGAVPVKKQSSISRESEEDNDVSADGTLNARDLDFVSSGKSLSEESAASENDFNMSGDDGTVASNQSKGPLQSLPVPQSGAEEECQDLSQGNLQKKKSKGKSQNKNAAEEDSAIQKQIKRSGQCKRQNSRGNDSCLMYSSPVSESCYDTYQHQERMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPRQQFSAPAVRMPNRTRRPVTQIVRGPCLQSPTKPVPAAAPAASDVTGESPTKKADEELKKNLETLPSFSSDEDDSVGGNHDLQKSISTALSALDDSSDRKNKSEAEKVAAVSAASTAAVIKQELPQTTSPVVNVQEKMSSADSLKAAQQDAGTSDQLAKIQATVAIEGSTEEENTDSGGEGMYRERDEFVVKIEDIETLKLALQTGKEPPAIWKVQKALLQKFVPEVRDGQREFAATNSYLGYFGDAKTKYKRVYVKFIENANKKEYVRVCSRKPRSKPVQSARTIHCKPSSSNNKTPDPPTPKPAAAKVSSVKPKAKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEAQSDEDELVPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMRKIDGMLNDNRKRLLSKLRLDNTFKSALEIFPELTVITRDSKTKSGGASVSKIKMNGKAYNKKTLRASKSTTKLAQEFTVDPEKIQLYSLYHSLHHYKYHIYLTCKEEISSVQKKSADLGQEEIVQLCMKNMKWVEDLFEKFGELLNRVQQKCS", "length": 1796, "header": "tr|A0A8V0ZQC7-1|A0A8V0ZQC7_CHICK Computationally mapped isoform of Glutamine and serine rich 1 OS=Gallus gallus OX=9031 GN=QSER1 PE=4 SV=1 CANONICAL=A0A8V0ZI64-1" }, "locus": { "chromosome": "5", "start_pos": 5846634, "end_pos": 5824928, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054680.1", "url": "https://www.ensembl.org/id/ENSGALT00010054680.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033036.1", "url": "https://www.ensembl.org/id/ENSGALP00010033036.1" } ] } }, { "isoform_ac": "A0A8V0ZQD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI64/entry#A0A8V0ZQD3-1", "sequence": { "sequence": "MMDRNYPPTPSFADPLAPAAAQPAAAWAYERGAGGPKPSLSYGGGHPSHSETDLLHRQTYTASHQLPGYSATHHPTGLSGIFDTGMHTSGSNTKETSVMNFLSAIESRTAQAVSSGSTLLPQFRAPSWQTGMHSSTATELFVTGALPTSGTFPPTSALSAYQHPNTFSSRNFATTPSLTLQDTTFSATSNGLLTTHDPLLQIKTSQGTVPAALTFERLGSSVLSTSVPPQSSTYRSAQESAPHLLQPQFSLLPSTIGGAQQVSQAYSTSVFTGSTASIDRALQRECSVIKHHQRPSSTQSVQAQLTVSQHSLHSYLTSTSGVNFQDTCRHSALSCSPVGDVTQVSNGGPQQKTSQVTVELAQSYASAVPSSGFPPASAAKVKNCSTKQPPRSTKTPKPQSIAPPVQTQSYAKTAQNQSSVITGQAQIYSTAQLPSLLSVSQSQNYISSQAQNVPPVSHSQDFSSSKVEKLPTLYKTLTFSGQSQTITSDSQTLSYSSDEQVLTSVPNESYSPQTRELSSVSQSQSYSSSHSQGLSPVSQSQVSFSSQSQVLSAVSPSESYSSGQSLTLTSPSLPFSASPRIQTLPASSPNQSYISLHSSQNTQSQESSSPQSQKFLPSVQSPPFASPAHSQALQNSRPSSETKTYVKRKSDSNLYASSKQEEELSMQDMQALQRQASLESSTQRLTDEEINAQDASYRVTKADDRYSQSVIRSNSRLEDQVVGLTLQGTKKEERMANTVEQLSQHIGHITNLSHDMKKAANLMQSTQVNVSSKELNQQHSLIHKVHESKASEQQGQVISTTPQVQPHALRHGHQLCLPGAQVLLESTCDLQILHQSILQSGLGQAKASPQVQRIQSPQQVTHPFLQMDGHIIQSNGGHSQQQLHTQNSEVMKMDISEPSKPLQQHLTTKDHFTQTNQHDSKNPFVSLSSICFPESMLLSDERNILSNVDDILAATAAACGVTPSDFAKSASNEEEIRSVENSEESKTQFRSMDVRHVSAGFNASPAIVGKPASINNISLNGGQITINLTPVSAIQTKAVNLNHQHIDASDQNVPTRMTSPTLGPGQEEQEQGAVPVKKQSSISRESEEDNDVSADGTLNARDLDFVSSGKSLSEESAASENDFNMSGDDGTVASNQSKGPLQSLPVPQSGAEEECQDLSQGNLQKKKSKGKSQNKNAAEEDSAIQKQIKRSGQCKRQNSRGNDSCLMYSSPVSESCYDTYQHQERMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPRQQFSAPAVRMPNRTRRPVTQIVRGPCLQSPTKPVPAAAPAASDVTGESPTKKADEELKKNLETLPSFSSDEDDSVGGNHDLQKSISTALSALDDSSDRKNKSEAEKVAAVSAASTAAVIKQELPQTTSPVVNVQEKMSSADSLKAAQQDAGTSDQLAKIQATVAIEGSTEEENTDSGGEGMYRERDEFVVKIEDIETLKLALQTGKEPPAIWKVQKALLQKFVPEVRDGQREFAATNSYLGYFGDAKTKYKRVYVKFIENANKKEYVRVCSRKPRSKPVQSARTIHCKPSSSNNKTPDPPTPKPAAAKVSSVKPKAKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEAQSDEDELVPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMRKIDGMLNDNRKRLLSKLRLDNTFKSALEIFPELTVITRDSKTKSGGASVSKIKMNGKAYNKKTLRASKSTTKLAQEFTVDPEKIQLYSLYHSLHHYKYHIYLTCKEEISSVQKKSADLGQEEIVQLCMKNMKWVEDLFEKFGELLNRVQQKCS", "length": 1818, "header": "tr|A0A8V0ZQD3-1|A0A8V0ZQD3_CHICK Computationally mapped isoform of Glutamine and serine rich 1 OS=Gallus gallus OX=9031 GN=QSER1 PE=4 SV=1 CANONICAL=A0A8V0ZI64-1" }, "locus": { "chromosome": "5", "start_pos": 5846634, "end_pos": 5813477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054687.1", "url": "https://www.ensembl.org/id/ENSGALT00010054687.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033041.1", "url": "https://www.ensembl.org/id/ENSGALP00010033041.1" } ] } }, { "isoform_ac": "A0A8V0ZQY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI64/entry#A0A8V0ZQY5-1", "sequence": { "sequence": "MPNFQKLVDCSLACHLLVLLLTILVVVSFLYNCMVLLIMFNFFLSLSYGGGHPSHSETDLLHRQTYTASHQLPGYSATHHPTGLSGIFDTGMHTSGSNTKETSVMNFLSAIESRTAQAVSSGSTLLPQFRAPSWQTGMHSSTATELFVTGALPTSGTFPPTSALSAYQHPNTFSSRNFATTPSLTLQDTTFSATSNGLLTTHDPLLQIKTSQGTVPAALTFERLGSSVLSTSVPPQSSTYRSAQESAPHLLQPQFSLLPSTIGGAQQVSQAYSTSVFTGSTASIDRALQRECSVIKHHQRPSSTQSVQAQLTVSQHSLHSYLTSTSGVNFQDTCRHSALSCSPVGDVTQVSNGGPQQKTSQVTVELAQSYASAVPSSGFPPASAAKVKNCSTKQPPRSTKTPKPQSIAPPVQTQSYAKTAQNQSSVITGQAQIYSTAQLPSLLSVSQSQNYISSQAQNVPPVSHSQDFSSSKVEKLPTLYKTLTFSGQSQTITSDSQTLSYSSDEQVLTSVPNESYSPQTRELSSVSQSQSYSSSHSQGLSPVSQSQVSFSSQSQVLSAVSPSESYSSGQSLTLTSPSLPFSASPRIQTLPASSPNQSYISLHSSQNTQSQESSSPQSQKFLPSVQSPPFASPAHSQALQNSRPSSETKTYVKRKSDSNLYASSKQEEELSMQDMQALQRQASLESSTQRLTDEEINAQDASYRVTKADDRYSQSVIRSNSRLEDQVVGLTLQGTKKEERMANTVEQLSQHIGHITNLSHDMKKAANLMQSTQVNVSSKELNQQHSLIHKVHESKASEQQGQVISTTPQVQPHALRHGHQLCLPGAQVLLESTCDLQILHQSILQSGLGQAKASPQVQRIQSPQQVTHPFLQMDGHIIQSNGGHSQQQLHTQNSEVMKMDISEPSKPLQQHLTTKDHFTQTNQHDSKNPFVSLSSICFPESMLLSDERNILSNVDDILAATAAACGVTPSDFAKSASNEEEIRSVENSEESKTQFRSMDVRHVSAGFNASPAIVGKPASINNISLNGGQITINLTPVSAIQTKAVNLNHQHIDASDQNVPTRMTSPTLGPGQEEQEQGAVPVKKQSSISRESEEDNDVSADGTLNARDLDFVSSGKSLSEESAASENDFNMSGDDGTVASNQSKGPLQSLPVPQSGAEEECQDLSQGNLQKKKSKGKSQNKNAAEEDSAIQKQIKRSGQCKRQNSRGNDSCLMYSSPVSESCYDTYQHQERMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPRQQFSAPAVRMPNRTRRPVTQIVRGPCLQSPTKPVPAAAPAASDVTGESPTKKADEELKKNLETLPSFSSDEDDSVGGNHDLQKSISTALSALDDSSDRKNKSEAEKVAAVSAASTAAVIKQELPQTTSPVVNVQEKMSSADSLKAAQQDAGTSDQLAKIQATVAIEGSTEEENTDSGGEGMYRERDEFVVKIEDIETLKLALQTGKEPPAIWKVQKALLQKFVPEVRDGQREFAATNSYLGYFGDAKTKYKRVYVKFIENANKKEYVRVCSRKPRSKPVQSARTIHCKPSSSNNKTPDPPTPKPAAAKVSSVKPKAKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEAQSDEDELVPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMRKIDGMLNDNRKRLLSKLRLDNTFKCLCVAFGEHL", "length": 1705, "header": "tr|A0A8V0ZQY5-1|A0A8V0ZQY5_CHICK Computationally mapped isoform of Glutamine and serine rich 1 OS=Gallus gallus OX=9031 GN=QSER1 PE=4 SV=1 CANONICAL=A0A8V0ZI64-1" }, "locus": { "chromosome": "5", "start_pos": 5843527, "end_pos": 5826591, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054665.1", "url": "https://www.ensembl.org/id/ENSGALT00010054665.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033025.1", "url": "https://www.ensembl.org/id/ENSGALP00010033025.1" } ] } }, { "isoform_ac": "A0A8V0ZQZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI64/entry#A0A8V0ZQZ1-1", "sequence": { "sequence": "MNKDIAVCIPKCRCLSYGGGHPSHSETDLLHRQTYTASHQLPGYSATHHPTGLSGIFDTGMHTSGSNTKETSVMNFLSAIESRTAQAVSSGSTLLPQFRAPSWQTGMHSSTATELFVTGALPTSGTFPPTSALSAYQHPNTFSSRNFATTPSLTLQDTTFSATSNGLLTTHDPLLQIKTSQGTVPAALTFERLGSSVLSTSVPPQSSTYRSAQESAPHLLQPQFSLLPSTIGGAQQVSQAYSTSVFTGSTASIDRALQRECSVIKHHQRPSSTQSVQAQLTVSQHSLHSYLTSTSGVNFQDTCRHSALSCSPVGDVTQVSNGGPQQKTSQVTVELAQSYASAVPSSGFPPASAAKVKNCSTKQPPRSTKTPKPQSIAPPVQTQSYAKTAQNQSSVITGQAQIYSTAQLPSLLSVSQSQNYISSQAQNVPPVSHSQDFSSSKVEKLPTLYKTLTFSGQSQTITSDSQTLSYSSDEQVLTSVPNESYSPQTRELSSVSQSQSYSSSHSQGLSPVSQSQVSFSSQSQVLSAVSPSESYSSGQSLTLTSPSLPFSASPRIQTLPASSPNQSYISLHSSQNTQSQESSSPQSQKFLPSVQSPPFASPAHSQALQNSRPSSETKTYVKRKSDSNLYASSKQEEELSMQDMQALQRQASLESSTQRLTDEEINAQDASYRVTKADDRYSQSVIRSNSRLEDQVVGLTLQGTKKEERMANTVEQLSQHIGHITNLSHDMKKAANLMQSTQVNVSSKELNQQHSLIHKVHESKASEQQGQVISTTPQVQPHALRHGHQLCLPGAQVLLESTCDLQILHQSILQSGLGQAKASPQVQRIQSPQQVTHPFLQMDGHIIQSNGGHSQQQLHTQNSEVMKMDISEPSKPLQQHLTTKDHFTQTNQHDSKNPFVSLSSICFPESMLLSDERNILSNVDDILAATAAACGVTPSDFAKSASNEEEIRSVENSEESKTQFRSMDVRHVSAGFNASPAIVGKPASINNISLNGGQITINLTPVSAIQTKAVNLNHQHIDASDQNVPTRMTSPTLGPGQEEQEQGAVPVKKQSSISRESEEDNDVSADGTLNARDLDFVSSGKSLSEESAASENDFNMSGDDGTVASNQSKGPLQSLPVPQSGAEEECQDLSQGNLQKKKSKGKSQNKNAAEEDSAIQKQIKRSGQCKRQNSRGNDSCLMYSSPVSESCYDTYQHQERMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPRQQFSAPAVRMPNRTRRPVTQIVRGPCLQSPTKPVPAAAPAASDVTGESPTKKADEELKKNLETLPSFSSDEDDSVGGNHDLQKSISTALSALDDSSDRKNKSEAEKVAAVSAASTAAVIKQELPQTTSPVVNVQEKMSSADSLKAAQQDAGTSDQLAKIQATVAIEGSTEEENTDSGGEGMYRERDEFVVKIEDIETLKLALQTGKEPPAIWKVQKALLQKFVPEVRDGQREFAATNSYLGYFGDAKTKYKRVYVKFIENANKKEYVRVCSRKPRSKPVQSARTIHCKPSSSNNKTPDPPTPKPAAAKVSSVKPKAKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEAQSDEDELVPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMRKIDGMLNDNRKRLLSKLRLDNTFKSALEIFPELTVITRDSKTKSGGASVSKIKMNGKAYNKKTLRASKSTTKLAQEFTVDPEKIQLYSLYHSLHHYKYHIYLTCKEEISSVQKKSADLGQEEIVQLCMKNMKWVEDLFEKFGELLNRVQQKCS", "length": 1793, "header": "tr|A0A8V0ZQZ1-1|A0A8V0ZQZ1_CHICK Computationally mapped isoform of Glutamine and serine rich 1 OS=Gallus gallus OX=9031 GN=QSER1 PE=4 SV=1 CANONICAL=A0A8V0ZI64-1" }, "locus": { "chromosome": "5", "start_pos": 5846634, "end_pos": 5820526, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054671.1", "url": "https://www.ensembl.org/id/ENSGALT00010054671.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033030.1", "url": "https://www.ensembl.org/id/ENSGALP00010033030.1" } ] } }, { "isoform_ac": "A0A8V0ZVZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI64/entry#A0A8V0ZVZ6-1", "sequence": { "sequence": "MPFSIGPPFHLYLSYGGGHPSHSETDLLHRQTYTASHQLPGYSATHHPTGLSGIFDTGMHTSGSNTKETSVMNFLSAIESRTAQAVSSGSTLLPQFRAPSWQTGMHSSTATELFVTGALPTSGTFPPTSALSAYQHPNTFSSRNFATTPSLTLQDTTFSATSNGLLTTHDPLLQIKTSQGTVPAALTFERLGSSVLSTSVPPQSSTYRSAQESAPHLLQPQFSLLPSTIGGAQQVSQAYSTSVFTGSTASIDRALQRECSVIKHHQRPSSTQSVQAQLTVSQHSLHSYLTSTSGVNFQDTCRHSALSCSPVGDVTQVSNGGPQQKTSQVTVELAQSYASAVPSSGFPPASAAKVKNCSTKQPPRSTKTPKPQSIAPPVQTQSYAKTAQNQSSVITGQAQIYSTAQLPSLLSVSQSQNYISSQAQNVPPVSHSQDFSSSKVEKLPTLYKTLTFSGQSQTITSDSQTLSYSSDEQVLTSVPNESYSPQTRELSSVSQSQSYSSSHSQGLSPVSQSQVSFSSQSQVLSAVSPSESYSSGQSLTLTSPSLPFSASPRIQTLPASSPNQSYISLHSSQNTQSQESSSPQSQKFLPSVQSPPFASPAHSQALQNSRPSSETKTYVKRKSDSNLYASSKQEEELSMQDMQALQRQASLESSTQRLTDEEINAQDASYRVTKADDRYSQSVIRSNSRLEDQVVGLTLQGTKKEERMANTVEQLSQHIGHITNLSHDMKKAANLMQSTQVNVSSKELNQQHSLIHKVHESKASEQQGQVISTTPQVQPHALRHGHQLCLPGAQVLLESTCDLQILHQSILQSGLGQAKASPQVQRIQSPQQVTHPFLQMDGHIIQSNGGHSQQQLHTQNSEVMKMDISEPSKPLQQHLTTKDHFTQTNQHDSKNPFVSLSSICFPESMLLSDERNILSNVDDILAATAAACGVTPSDFAKSASNEEEIRSVENSEESKTQFRSMDVRHVSAGFNASPAIVGKPASINNISLNGGQITINLTPVSAIQTKAVNLNHQHIDASDQNVPTRMTSPTLGPGQEEQEQGAVPVKKQSSISRESEEDNDVSADGTLNARDLDFVSSGKSLSEESAASENDFNMSGDDGTVASNQSKGPLQSLPVPQSGAEEECQDLSQGNLQKKKSKGKSQNKNAAEEDSAIQKQIKRSGQCKRQNSRGNDSCLMYSSPVSESCYDTYQHQERMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPRQQFSAPAVRMPNRTRRPVTQIVRGPCLQSPTKPVPAAAPAASDVTGESPTKKADEELKKNLETLPSFSSDEDDSVGGNHDLQKSISTALSALDDSSDRKNKSEAEKVAAVSAASTAAVIKQELPQTTSPVVNVQEKMSSADSLKAAQQDAGTSDQLAKIQATVAIEGSTEEENTDSGGEGMYRERDEFVVKIEDIETLKLALQTGKEPPAIWKVQKALLQKFVPEVRDGQREFAATNSYLGYFGDAKTKYKRVYVKFIENANKKEYVRVCSRKPRSKPVQSARTIHCKPSSSNNKTPDPPTPKPAAAKVSSVKPKAKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEAQSDEDELVPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMRKIDGMLNDNRKRLLSKLRLDNTFKSALEIFPELTVITRDSKTKSGGASVSKIKMNGKAYNKKTLRASKSTTKLAQEFTVDPEKIQLYSLYHSLHHYKYHIYLTCKEEISSVQKKSADLGQEEIVQLCMKNMKWVEDLFEKFGELLNRVQQKCS", "length": 1791, "header": "tr|A0A8V0ZVZ6-1|A0A8V0ZI64_CHICK Computationally mapped isoform of Glutamine and serine rich 1 OS=Gallus gallus OX=9031 GN=QSER1 PE=4 SV=1 CANONICAL=A0A8V0ZI64-1" }, "locus": { "chromosome": "5", "start_pos": 5846634, "end_pos": 5823229, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054668.1", "url": "https://www.ensembl.org/id/ENSGALT00010054668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033028.1", "url": "https://www.ensembl.org/id/ENSGALP00010033028.1" } ] } }, { "isoform_ac": "A0A8V0ZW01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI64/entry#A0A8V0ZW01-1", "sequence": { "sequence": "MLEVLCLSYGGGHPSHSETDLLHRQTYTASHQLPGYSATHHPTGLSGIFDTGMHTSGSNTKETSVMNFLSAIESRTAQAVSSGSTLLPQFRAPSWQTGMHSSTATELFVTGALPTSGTFPPTSALSAYQHPNTFSSRNFATTPSLTLQDTTFSATSNGLLTTHDPLLQIKTSQGTVPAALTFERLGSSVLSTSVPPQSSTYRSAQESAPHLLQPQFSLLPSTIGGAQQVSQAYSTSVFTGSTASIDRALQRECSVIKHHQRPSSTQSVQAQLTVSQHSLHSYLTSTSGVNFQDTCRHSALSCSPVGDVTQVSNGGPQQKTSQVTVELAQSYASAVPSSGFPPASAAKVKNCSTKQPPRSTKTPKPQSIAPPVQTQSYAKTAQNQSSVITGQAQIYSTAQLPSLLSVSQSQNYISSQAQNVPPVSHSQDFSSSKVEKLPTLYKTLTFSGQSQTITSDSQTLSYSSDEQVLTSVPNESYSPQTRELSSVSQSQSYSSSHSQGLSPVSQSQVSFSSQSQVLSAVSPSESYSSGQSLTLTSPSLPFSASPRIQTLPASSPNQSYISLHSSQNTQSQESSSPQSQKFLPSVQSPPFASPAHSQALQNSRPSSETKTYVKRKSDSNLYASSKQEEELSMQDMQALQRQASLESSTQRLTDEEINAQDASYRVTKADDRYSQSVIRSNSRLEDQVVGLTLQGTKKEERMANTVEQLSQHIGHITNLSHDMKKAANLMQSTQVNVSSKELNQQHSLIHKVHESKASEQQGQVISTTPQVQPHALRHGHQLCLPGAQVLLESTCDLQILHQSILQSGLGQAKASPQVQRIQSPQQVTHPFLQMDGHIIQSNGGHSQQQLHTQNSEVMKMDISEPSKPLQQHLTTKDHFTQTNQHDSKNPFVSLSSICFPESMLLSDERNILSNVDDILAATAAACGVTPSDFAKSASNEEEIRSVENSEESKTQFRSMDVRHVSAGFNASPAIVGKPASINNISLNGGQITINLTPVSAIQTKAVNLNHQHIDASDQNVPTRMTSPTLGPGQEEQEQGAVPVKKQSSISRESEEDNDVSADGTLNARDLDFVSSGKSLSEESAASENDFNMSGDDGTVASNQSKGPLQSLPVPQSGAEEECQDLSQGNLQKKKSKGKSQNKNAAEEDSAIQKQIKRSGQCKRQNSRGNDSCLMYSSPVSESCYDTYQHQERMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPRQQFSAPAVRMPNRTRRPVTQIVRGPCLQSPTKPVPAAAPAASDVTGESPTKKADEELKKNLETLPSFSSDEDDSVGGNHDLQKSISTALSALDDSSDRKNKSEAEKVAAVSAASTAAVIKQELPQTTSPVVNVQEKMSSADSLKAAQQDAGTSDQLAKIQATVAIEGSTEEENTDSGGEGMYRERDEFVVKIEDIETLKLALQTGKEPPAIWKVQKALLQKFVPEVRDGQREFAATNSYLGYFGDAKTKYKRVYVKFIENANKKEYVRVCSRKPRSKPVQSARTIHCKPSSSNNKTPDPPTPKPAAAKVSSVKPKAKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEAQSDEDELVPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMRKIDGMLNDNRKRLLSKLRLDNTFKSALEIFPELTVITRDSKTKSGGASVSKIKMNGKAYNKKTLRASKSTTKLAQEFTVDPEKIQLYSLYHSLHHYKYHIYLTCKEEISSVQKKSADLGQEEIVQLCMKNMKWVEDLFEKFGELLNRVQQKCS", "length": 1785, "header": "tr|A0A8V0ZW01-1|A0A8V0ZI64_CHICK Computationally mapped isoform of Glutamine and serine rich 1 OS=Gallus gallus OX=9031 GN=QSER1 PE=4 SV=1 CANONICAL=A0A8V0ZI64-1" }, "locus": { "chromosome": "5", "start_pos": 5846634, "end_pos": 5814703, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054675.1", "url": "https://www.ensembl.org/id/ENSGALT00010054675.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033033.1", "url": "https://www.ensembl.org/id/ENSGALP00010033033.1" } ] } }, { "isoform_ac": "A0A8V0ZW07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI64/entry#A0A8V0ZW07-1", "sequence": { "sequence": "MKICVSDSLSYGGGHPSHSETDLLHRQTYTASHQLPGYSATHHPTGLSGIFDTGMHTSGSNTKETSVMNFLSAIESRTAQAVSSGSTLLPQFRAPSWQTGMHSSTATELFVTGALPTSGTFPPTSALSAYQHPNTFSSRNFATTPSLTLQDTTFSATSNGLLTTHDPLLQIKTSQGTVPAALTFERLGSSVLSTSVPPQSSTYRSAQESAPHLLQPQFSLLPSTIGGAQQVSQAYSTSVFTGSTASIDRALQRECSVIKHHQRPSSTQSVQAQLTVSQHSLHSYLTSTSGVNFQDTCRHSALSCSPVGDVTQVSNGGPQQKTSQVTVELAQSYASAVPSSGFPPASAAKVKNCSTKQPPRSTKTPKPQSIAPPVQTQSYAKTAQNQSSVITGQAQIYSTAQLPSLLSVSQSQNYISSQAQNVPPVSHSQDFSSSKVEKLPTLYKTLTFSGQSQTITSDSQTLSYSSDEQVLTSVPNESYSPQTRELSSVSQSQSYSSSHSQGLSPVSQSQVSFSSQSQVLSAVSPSESYSSGQSLTLTSPSLPFSASPRIQTLPASSPNQSYISLHSSQNTQSQESSSPQSQKFLPSVQSPPFASPAHSQALQNSRPSSETKTYVKRKSDSNLYASSKQEEELSMQDMQALQRQASLESSTQRLTDEEINAQDASYRVTKADDRYSQSVIRSNSRLEDQVVGLTLQGTKKEERMANTVEQLSQHIGHITNLSHDMKKAANLMQSTQVNVSSKELNQQHSLIHKVHESKASEQQGQVISTTPQVQPHALRHGHQLCLPGAQVLLESTCDLQILHQSILQSGLGQAKASPQVQRIQSPQQVTHPFLQMDGHIIQSNGGHSQQQLHTQNSEVMKMDISEPSKPLQQHLTTKDHFTQTNQHDSKNPFVSLSSICFPESMLLSDERNILSNVDDILAATAAACGVTPSDFAKSASNEEEIRSVENSEESKTQFRSMDVRHVSAGFNASPAIVGKPASINNISLNGGQITINLTPVSAIQTKAVNLNHQHIDASDQNVPTRMTSPTLGPGQEEQEQGAVPVKKQSSISRESEEDNDVSADGTLNARDLDFVSSGKSLSEESAASENDFNMSGDDGTVASNQSKGPLQSLPVPQSGAEEECQDLSQGNLQKKKSKGKSQNKNAAEEDSAIQKQIKRSGQCKRQNSRGNDSCLMYSSPVSESCYDTYQHQERMRQKIKEVEEKQPEVKTGFIASFLDFLKSGPRQQFSAPAVRMPNRTRRPVTQIVRGPCLQSPTKPVPAAAPAASDVTGESPTKKADEELKKNLETLPSFSSDEDDSVGGNHDLQKSISTALSALDDSSDRKNKSEAEKVAAVSAASTAAVIKQELPQTTSPVVNVQEKMSSADSLKAAQQDAGTSDQLAKIQATVAIEGSTEEENTDSGGEGMYRERDEFVVKIEDIETLKLALQTGKEPPAIWKVQKALLQKFVPEVRDGQREFAATNSYLGYFGDAKTKYKRVYVKFIENANKKEYVRVCSRKPRSKPVQSARTIHCKPSSSNNKTPDPPTPKPAAAKVSSVKPKAKQPKVKAEPPPKKRKKWKEEFSSSQSDSSPEAQSDEDELVPPAPFVTRFLNTRAMKETFKSYMELLVSIALDPDTMQALEKSNDELLLPHMRKIDGMLNDNRKRLLSKLRLDNTFKSALEIFPELTVITRDSKTKSGGASVSKIKMNGKAYNKKTLRASKSTTKLAQEFTVDPEKIQLYSLYHSLHHYKYHIYLTCKEEISSVQKKSADLGQEEIVQLCMKNMKWVEDLFEKFGELLNRVQQKCS", "length": 1787, "header": "tr|A0A8V0ZW07-1|A0A8V0ZI64_CHICK Computationally mapped isoform of Glutamine and serine rich 1 OS=Gallus gallus OX=9031 GN=QSER1 PE=4 SV=1 CANONICAL=A0A8V0ZI64-1" }, "locus": { "chromosome": "5", "start_pos": 5846634, "end_pos": 5814191, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054684.1", "url": "https://www.ensembl.org/id/ENSGALT00010054684.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033038.1", "url": "https://www.ensembl.org/id/ENSGALP00010033038.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 968, "start_aa": "Thr", "end_pos": 968, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr968", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1008, "end_pos": 1010, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1033, "end_pos": 1035, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1130, "end_pos": 1132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1141, "end_pos": 1143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1208, "end_pos": 1210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1275, "end_pos": 1277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1363, "end_pos": 1365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1557, "end_pos": 1559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 757, "end_pos": 759, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZI64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI64" }, { "id": "PF13926", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13926" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4211", "eco_id": "ECO_0000259", "start_pos": 1614, "end_pos": 1735, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 968 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1008, "end_pos": 1010 }, { "start_pos": 1022, "end_pos": 1024 }, { "start_pos": 1033, "end_pos": 1035 }, { "start_pos": 1130, "end_pos": 1132 }, { "start_pos": 1141, "end_pos": 1143 }, { "start_pos": 1208, "end_pos": 1210 }, { "start_pos": 1275, "end_pos": 1277 }, { "start_pos": 1363, "end_pos": 1365 }, { "start_pos": 1557, "end_pos": 1559 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 596, "end_pos": 598 }, { "start_pos": 757, "end_pos": 759 }, { "start_pos": 775, "end_pos": 777 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZI84-1", "uniprot_ac": "A0A8V0ZI84", "uniprot_id": "A0A8V0ZI84_CHICK", "mass": { "chemical_mass": 103533.0, "monoisotopic_mass": 103533.0 }, "refseq": { "ac": "XP_015147486", "name": "major intrinsically disordered Notch2-binding receptor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147486" }, "gene_names": [ { "name": "MINAR1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZI84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI84" } ] }, { "name": "DD1", "type": "synonym", "evidence": [ { "id": "XP_015147486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147486" } ] }, { "name": "KIAA1024", "type": "synonym", "evidence": [ { "id": "XP_015147486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147486" } ] }, { "name": "MINAR1", "type": "synonym", "evidence": [ { "id": "XP_015147486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147486" } ] } ], "protein_names": [ { "name": "Membrane integral NOTCH2 associated receptor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZI84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI84/entry#names_and_taxonomy" } ] }, { "name": "major intrinsically disordered Notch2-binding receptor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015147486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147486" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147486.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147486" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZI84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI84" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MINAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI84", "locus": { "chromosome": "10", "start_pos": 12763859, "end_pos": 12778588, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019836", "url": "https://www.ensembl.org/id/ENSGALG00010019836" } ] } } ], "crossref": [ { "id": "A0A8V0ZI84", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZI84", "database": "AlphaFoldDB", "categories": [] }, { "id": "415485", "url": "https://www.ncbi.nlm.nih.gov/gene/415485", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IMQANYA", "url": "https://omabrowser.org/oma/group/IMQANYA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI84", "url": "https://www.orthodb.org/?gene=A0A8V0ZI84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31530", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31530", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31530:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31530:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22948", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22948", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015147486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147486", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESNQETSLFLVKILEELDTKQNTVSYQDLCKSLCARFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMRCTVNNQQSKKIMVAADIVTIFNLIQMNGGVAKEKLPVARQKVKKKESFESCRSDTEICNMAECVPNCELSEQDFSQGFAVRRSSKCRKMDCKDCQQFVPSSEPNFLLGVNKEMKGRAASLDRLQALASYSIATSPPCEMQSTYFPMNIENESISDQDSLPISTGLKETFISNDEPFVMQSCVQKRNIFKEDFHNLITISPNLIPSNKKPEDGHREPQNRKESSKQTFFNHSFEMPYSSQYLNPVYSPIPDKRRVKHESLDDLQASTYFGPTTILGPQDTKKWTGKPTKQTAWPAKSWSLNTEEVPDFERSFFNRNQSEEKPRYQSSNNPSPNFPSADRHQSYLNPKDQQPIMQTNYAVKQNGHKPKEIPSILDVEKHEPVKKFKDKSINCTSVQILSIDRTMSVGTQTEQQVLDHKKCKDLCAPGQAKYAERHSLKHSDDDSEIVSDDISDIFRFLDDMSISGSTGVMQSSCYNSTGSLSQVHKSDCDSSPEHNLTKISNGSACNKLDKVVRADISNVDDELKTSVCKLVLRIGEIEKKLESLSGVREEISQVLGKLSKLDQKIQQPEKVSVQIDLNSLTSDAASDESNSPHIFQCHNTPHGGKLENNPEWCCSDASGSNSESLRVKALKKSLFTRRSSRSLTEENSATESKIASISNSPRDWRAITYTNKVGITEEEMKDRDGGENKDWHRKSKEADRQYEIPQPHRLPKQPKDAFLIEQVFSPHPYPASLKSHMKSNPLYTDMRLTELAEVKRAQPSWTIEEYTRNSGDKGKIAALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPICTMKS", "length": 916, "header": "tr|A0A8V0ZI84-1|A0A8V0ZI84_CHICK Isoform 1 of Membrane integral NOTCH2 associated receptor 1 OS=Gallus gallus OX=9031 GN=MINAR1 PE=3 SV=1 CANONICAL=A0A8V0ZI84-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZI84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI84/entry#A0A8V0ZI84-1", "sequence": { "sequence": "MESNQETSLFLVKILEELDTKQNTVSYQDLCKSLCARFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMRCTVNNQQSKKIMVAADIVTIFNLIQMNGGVAKEKLPVARQKVKKKESFESCRSDTEICNMAECVPNCELSEQDFSQGFAVRRSSKCRKMDCKDCQQFVPSSEPNFLLGVNKEMKGRAASLDRLQALASYSIATSPPCEMQSTYFPMNIENESISDQDSLPISTGLKETFISNDEPFVMQSCVQKRNIFKEDFHNLITISPNLIPSNKKPEDGHREPQNRKESSKQTFFNHSFEMPYSSQYLNPVYSPIPDKRRVKHESLDDLQASTYFGPTTILGPQDTKKWTGKPTKQTAWPAKSWSLNTEEVPDFERSFFNRNQSEEKPRYQSSNNPSPNFPSADRHQSYLNPKDQQPIMQTNYAVKQNGHKPKEIPSILDVEKHEPVKKFKDKSINCTSVQILSIDRTMSVGTQTEQQVLDHKKCKDLCAPGQAKYAERHSLKHSDDDSEIVSDDISDIFRFLDDMSISGSTGVMQSSCYNSTGSLSQVHKSDCDSSPEHNLTKISNGSACNKLDKVVRADISNVDDELKTSVCKLVLRIGEIEKKLESLSGVREEISQVLGKLSKLDQKIQQPEKVSVQIDLNSLTSDAASDESNSPHIFQCHNTPHGGKLENNPEWCCSDASGSNSESLRVKALKKSLFTRRSSRSLTEENSATESKIASISNSPRDWRAITYTNKVGITEEEMKDRDGGENKDWHRKSKEADRQYEIPQPHRLPKQPKDAFLIEQVFSPHPYPASLKSHMKSNPLYTDMRLTELAEVKRAQPSWTIEEYTRNSGDKGKIAALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPICTMKS", "length": 916, "header": "tr|A0A8V0ZI84-1|A0A8V0ZI84_CHICK Isoform 1 of Membrane integral NOTCH2 associated receptor 1 OS=Gallus gallus OX=9031 GN=MINAR1 PE=3 SV=1 CANONICAL=A0A8V0ZI84-1" }, "locus": { "chromosome": "10", "start_pos": 12772684, "end_pos": 12765172, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047907.1", "url": "https://www.ensembl.org/id/ENSGALT00010047907.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028305.1", "url": "https://www.ensembl.org/id/ENSGALP00010028305.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HSZ1-1", "protein_name": "Major intrinsically disordered Notch2-binding receptor 1", "gene_name": "Minar1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEANQEASLFLVKILEELDSKQNTVSYQDLCKSLCAQFDLSQLTKLRSVLFYTACLDPNFPATLFKDKMKCSVNNQQSKKIMVAADIVTIFNLIQMNGGTAKEKLPTSCPKVRKKEASFESCRSDTEVCNPTVCEPLNCELGERPFSRGYPTRQSSKSRKRDCKECPQFVPASEPNFLLGVSKEVKNRAASLDRLQALSPYSMASPQPCEMQRTYFPMNIENESISDQDSLSISQGIKEPFISSEEPFVVQSCVQKRNIFKEEFHNLMTVSPSLVGPPNKTEGDRGETQNQKELHKTHFFNHSFEMPYHNQYLNPVYSPIPDKRRAKHESLDDLQASTYFGPTPVMGTQDARRCPGKSSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSGSQTPTFSGPDRHPTYLVPKDQQKVLPAGYAVKPNGLKSKEISSPVDLEKHEAVKKFKEKSISCTSGQHSSDTSSVGTQTEQHVLDAPKCKDLCTLGQAKYSDRHATMKHSDDDSEIVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLQKSDCDSSPEHNLAKITNGVTSSKGDKCNRPENVHHSEEELKTSVCKLVLRIGEIERKLESLSGVREEISQVLGKLNKLDQKIQQPEKVNVQIDLNSLTSEAPSDDSVSPRVFRAHSGSHGPKLENSPDWCCSDASGSNSESLRVKALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYTNRMSLNEEEIKDAGPGDNKDWHRKSKEADRQYDIPPQHRLPKQPKEGFLVEQVFSPHPYPASLKAHLKSNPLYTDMRLTELAEVKRGQPSWTIEEYARHSGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALITAAACTVILVIVVPICTMKS", "length": 918 }, "evidence": [ { "id": "A0A8V0ZI84", "url": "https://omabrowser.org/oma/group/A0A8V0ZI84/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1L4W4-1", "protein_name": "Membrane integral NOTCH2 associated receptor 1", "gene_name": "MINAR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METSQDTSLFLVKILEELDSKQNTVSYQDLCKSLCARFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCTVNNQQSKKIMVAADIVTIFNLIQMNGGAAKEKLPSGRQKARKKEASFDSCRSDTEICGAAECEALDCEMNDRPFSRGYPPRQSSKCRKMDCKDCPQFVPASEPNFLLGVSKEGKHRAASLDRLQALAPYSVASPQPCEMQRTYFPMNIENESMSDQDSLPLAQGIKETFIANEEPFVVQSCVQKRNIFKEDFHNLMAVSPGLAGPATKAEGEHGEPQGRKEAHKTPFPNHSFEMPYNSQYLNPVYSPVPDKRRAKHESLDDLQASTYFGPTPVMGTQEARRCPGRPSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSSSQTPSFPTPDRRPAYLTPQDQQPILPVGYAAKPNGLKSKEISSPVDLEKHEPVKKFKDKSISCTSGQLSSDTSSVGTQTEQHVLEPKKCKDLCASGQGKFSDRHTMKQSDDDSEVVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLHKSDCDSSPEHNRAKIANGLPSSKGEKGNRPENGHHSEEELKTSVCKLVLRIGEIERKLESLSGVREEISQVLGKLNKLDQKMQQPEKVSVQIDLNSLTSEAPSDESASPRMFRAHNGPHGPKLENSADWCCSDASGSNSESLRVQALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYPNRVGVGEEEIKDRGPGDSTDWHRKSKEADRQYDLPPQHRLPKQPQDGFLVEQVFSPHPYPASLKAHMKNNPLYTDMRLTELAEVKRGQPSWTIEEYARNAGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPICTMKS", "length": 917 }, "evidence": [ { "id": "A0A8V0ZI84", "url": "https://omabrowser.org/oma/group/A0A8V0ZI84/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZJ47-1", "protein_name": "Major intrinsically disordered Notch2-binding receptor 1", "gene_name": "Minar1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEANQEASLFLVKILEELDSKQNTVSYQDLCKSLCAQFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCSVNNQQSKKIMVAADIVTIFNLIQMNGGTAKEKLPTSCHKVRKEEASFESCRSDAEVCSPTVCEPLNCELSERPFSRGYPTRQSSKCRKMDCKECPQFVPASEPNFLLGVSKEVKNRAASLDRLQALSPYSVASPQPCEMQRTYFPMNIENESISDQDSLPIGQGIKETFISSEEPFMVQSCVQKRNIFKEDFHNLMTVSPSLVGTTNKAEEDHGEPRSQKELHKPPFFNHSFEMPYHSQYLNPVYSPIPDKRRAKHESLDDLQASTYFGPTPVMGTQDTRRCPGRPSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSGNQTPNFSGPDRHPVYLVPKDQQKVLPAGYAVKPNGLKSKEIPSPVDLEKHEAVKKFKDKSISCTSGQHSSDTSSVGTQTEQHVLDPPKCKDLCSAGQAKYSDRHAMKHSDDDSEIVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLHKSDCDSSPEHNLAKITNGVSGSKGDKCNRPENVHHSEEELKSSVCKLVLRIGEIERKLESLAGVREEISQVLGKLNKLDQKIQQPEKVNVQIDLNSLTSEAPSDDSASPRVFHAHSGSHGPKLENSPDWCCSDVSGSNSESLRVKALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYTNRMSLNEEEIKDAGPANNKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHPYPSSLKAHMKSNPLYTDMRLTELAEVKRGQPSWNIEEYARNTGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALITAAACTVILVIVVPICTMKS", "length": 917 }, "evidence": [ { "id": "A0A8V0ZI84", "url": "https://omabrowser.org/oma/group/A0A8V0ZI84/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BL03-1", "protein_name": "Membrane integral NOTCH2 associated receptor 1", "gene_name": "MINAR1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "METNQETSLFLVKILEELDSKQNTVSYQDLCKSLCARFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCAVNNQQSKKIMVAADIVTIFNLIQMNGGAAKEKLPGGRQKMRKKDASFDSCRSDTEICSAAECEPLNCELSDRPFSRGYPTRQSSKCRKVDCKDCPQFIPASEPNFLLGVSKDVKNRAASLDRLQALAPYSVASPQPCEMQRTYFPMNLESESMSDQDSLPLPQGIKQTFISNDEPFVVQSCVQKRNIFKEDFHNLMAVSPGLASPANKAEGEHRKSQGRKESHKTPFPHHSFEMPYSSQYLNPEYSPVPDKRRAKHESLDDLQASTYFGPTPVMGPQEARRCPGKTGKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSNSQTPNFPTPDRCPAYLTPQDQQPILPVGYSAKPNGLKSKEIPSPVDLEKHEPVKKFKDKSISCTSGQLSSDTSSVGTQTDLHVLEPKKGKDLCTPGQGKYSDRHAVKHSDDDSEVVSDDISDIFRFLDDMSISGSTGVMQSSCYNSTGSLSQLHKSDCDSSPEHHLTRIANGLPSSQGEKGSRPENSHHSEEELKTSVCKLVLRIGEIERKLESLSGVREEISQVLGKLNKLDQKMQQPEKVSVQIDLNSLTSEAPSDESASPRMFRAHKGAHGPKLENTADWCCSDASGSNSESLRVQALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYSNRMGISEEEIKERGPGDSKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHPYPASLKAHMKSNPLYTDMRLTELAEVKRGQPSWTIEEYARNSGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALIAAAACTVILVIVVPICTMKS", "length": 917 }, "evidence": [ { "id": "A0A8V0ZI84", "url": 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"MEANQEASLFLVKILEELDSKQNTVSYQDLCKSLCAQFDLSQLAKLRSVLFYTACLDPNFPATLFKDKMKCSVNNQQSKKIMVAADIVTIFNLIQMNGGTAKEKLPMSCHKVRKKEASFESCRSDTEVCSPTVCEPLNCELSERPFSRGYPTRQSSKCRKMDCKECPQFVPASEPNFLLGVSKEVKNRAASLDRLQALSPYSVASPQPCEMQRTYFPMNIENEPMSDQDSLPISQGIKETFISSEEPFVVQSCVQKRNIFKEDFHNLMTVSPSLVGTTNKAEEGHGEPQSQKELHKPPFFNHSFEMPYHNQYLNPVYSPIPDKRRAKHESLDDLQASTYFGPTPVMGTQDTRRCPGRSSKQTPWPAKSWSLNTEEVPDFERSFFNRNPSEEKLRYPNSGSQTPNFSGPDRHPVYLVPKDQQKVLPAGYAVKPNGLKSKEISSPVDLEKHEAVKKFKDKSISCTSGQHSSDTSSVGTQTEQHVLDPPKCKDLCTSGQAKYGDRHAMKQSDDDSEIVSDDISDIFRFLDDMSISGSTGVIQSSCYNSTGSLSQLHKSDCDSSPEHHLAKITNGVSSGKGDKCNRPENVHHSEEELKSSVCKLVLRIGEIERKLESLSGVREEISQVLGKLNKLDQKIQQPEKVNVQIDLNSLTSEAPSDDSASPRVFRAHSGSHGPKLENSPDWCCSDASGSNSESLRVKALKKSLFTRPSSRSLTEENSATESKIASISNSPRDWRTITYTNRMSLNEEEIKDAGPANNKDWHRKSKEADRQYDIPPQHRLPKQPKDGFLVEQVFSPHPYPTSLKGHMKSNPLYTDMRLTELAEVKRGQPSWTIEEYARNSGDKGKLTALDLQTQESLNPNNLEYWMEDIYTPGYDSLLKRKEAEFRRAKVCKIAALITAAACTVILVIVVPICTMKS", "length": 917 }, "evidence": [ { "id": "A0A8V0ZI84", "url": 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"database": "UniProtKB", "id": "A0A8V0ZI84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZI84", "database": "UniProtKB", "url": 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"METNGESGGANPTPMVITATTDFYTWDYSISWDDGTLPELCEKQAVQGFARTYQPAIYLLLSLLGTVGNGLVLLTHTRYRQARSITDVCLLHLALSDLLLLLTLPFAVTAMLQGWSPDTAACKVLQGVYALNFYSGFLFLTCISMDRYVAIVRVPAACRLRPRARRHGWLTVGLAWLLAALLALPQFVYGKAERHQDLHICRVVFPPAVSRAARGATNLTQVVLGFAVPFVVMASCYAAVARTLLAARGAQPHRALRVLLALVLVFVALQLPHSLMVLLDTAELLASWELSCAQSRRKDLALLVTSGLASLRCCLNPLLYAFLGQRFRRELWLLASDAGCVGNIDTRCPGCPSPRQRSSLSTCQDVA", "length": 367, "header": "tr|A0A8V0ZI85-1|A0A8V0ZI85_CHICK Isoform 1 of C-C chemokine receptor type 10 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZI85-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZI85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI85/entry#A0A8V0ZI85-1", "sequence": { "sequence": 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"sequence": { "sequence": "MGELRVRSVLVTGANRGIGLGFVQHLLALPNPPEWVFATCRDPKGQRAQKLASKHPNLVIVPLEVTDPTSIRAAAASVGERLKGSGLNLLINNAGIARANTIDNETLKDMSEVYTTNTIAPLLLGQAFLPLLKKAAQENPGSGLSCSKAAIINISSTAGSIQDLYLWQYGQALSYRCSKAALNMLTRCQSMGYREHGIFCVALHPGWVKTDMGGTLEDKSRVTVDESVGGMLKVLSNLSEKDSGAFLNWEGKVMAW", "length": 256, "header": "tr|A0A8V0ZNM3-1|A0A8V0ZNM3_CHICK Computationally mapped isoform of C-factor OS=Gallus gallus OX=9031 GN=LOC415661 PE=1 SV=1 CANONICAL=A0A8V0ZI86-1" }, "locus": { "chromosome": "11", "start_pos": 1081628, "end_pos": 1070581, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054706.1", "url": "https://www.ensembl.org/id/ENSGALT00010054706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033055.1", "url": "https://www.ensembl.org/id/ENSGALP00010033055.1" } ] } }, { "isoform_ac": "A0A8V0ZNM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI86/entry#A0A8V0ZNM8-1", "sequence": { "sequence": "MGELRVRSVLVTGANRGIGLGLVQHLLALPNPPEWVFATCRDPKGQRAQELQKLASKHPNLVIVPLEVTDPASIKAAAASVGERLKGSGLNLLINNAGVLNANTLETETLKDMLHVYTTNTIAPLLLSQAFLPLLKKAAQESPGSRMSCSKAAIVNMSSTAGSIKEVFLWESAQCISYRCSKAALNMLTRCQSMGYREHGILCVALHPGWVQTDMGNVAGCTELQKLASKHPNLVIVPLEVTDPASIKAAAASVGERLKGSGLNLLINNAGIAKTNSLDTETLDNMSQLFTTNTIAPLLLGQAFLPLLKKAAQGSPGSGMSCSKAAIVNMSSIGGSIKEMYLWEAAHCVAYRCSKAALNMLTRCQSMGYREHGILCVALHPGWVQTDMGNAAGYTPPLTVDASVGGMLKVLSNLSEKDSGAFLDWEGNVVAW", "length": 432, "header": "tr|A0A8V0ZNM8-1|A0A8V0ZNM8_CHICK Computationally mapped isoform of C-factor-like OS=Gallus gallus OX=9031 GN=LOC415661 PE=1 SV=1 CANONICAL=A0A8V0ZI86-1" }, "locus": { "chromosome": "11", "start_pos": 1090791, "end_pos": 1075686, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054712.1", "url": "https://www.ensembl.org/id/ENSGALT00010054712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033060.1", "url": "https://www.ensembl.org/id/ENSGALP00010033060.1" } ] } }, { "isoform_ac": 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"total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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{}, "gene_names": [ { "name": "OBSL1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ] } ], "protein_names": [ { "name": "Obscurin like cytoskeletal adaptor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OBSL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1", "locus": { "chromosome": "7", "start_pos": 21694759, "end_pos": 21681358, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021177", "url": "https://www.ensembl.org/id/ENSGALG00010021177" } ] } } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIA1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP85", "url": "https://www.orthodb.org/?gene=A0A8V0ZP85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35971", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35971", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35971:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35971:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESHGAAPRFLAYPRAFTAQSGTDAMLRCQIAGDPRPSVLWEKDTAPIHPSGRFCMEAEGDMYSLRVSCVTPQDGGLYVCKAKNCVGETYAAATLRVEAEEHQQEEEEEEGRAGGRAPTFLVGPTSVRVCRGEDVTFSCRVLGQPCPLLEWEKDGHRLRDLFESSHFAVGRQPEDWHYLKLFGVRPPDAGVYVCRARSGSKEALAAAVLLVEPRCSPSDSTQPRRLRHACTDTWAPAPNGTPRAKAFAVSAGKHAKFRCYVTGKPKPEIIWQKDGKAVAPGRRHLIYEDREGYFILKVLYCRPRDQGLYVCTASNTAGQTLSAVQLQVKEHRLRFQVPLEDVEVAEREDAVLECQVPLGSIPTAWFLEDRELQPSHKYVMEECGVVRRLTIRDARTDDDGIYLCQMKDRGRSIAEVSVRGLIVKRLPRKLDVMEGENAAFCVETQEAVEGISWTRNGLQLHESPRAVLKSFGRTHLLVLVHVTREDAGIICFSVGESLTSSQLRVKCVKRDPPGVPMAAQLSTEQSNAALLTWCPAPDVHHRPPSAYIVERREAAGGSWVQCLSTELPGRVQVLGDSVPREADYCFRVCAVNKHGRSDPVEFPGCVHLVPAVHLERGLQDARVRDGEDARFSVELSASVQGEWFLNGTRLQSEESGRFSVQHCGTEHSLLIRSARLRESGARITFVASSVRDSAILHVQAPQARIAPVPEARRLRELLAGLPLLLECEVSPAGVPVCWLKDGEAVVPSESLGIQSEGCWRRLHIPTAVPSDSGTYTCDAGDDTVSFVVTVSEAPVRIISSNEETPHTYMAGQRVELWCQLSHAEAPVRWYKDGEEVEEGESLVLEREGPRCRLVLPCACPQDTGEFVCDVGGDSVFYTITVAAPQARIAPVPEAQQLRELLAGLPLLLECEVSPAGAPVRWLKDGEAVVPSESLGIQAEGCWRRLHIPTAVPSDSGTYTCDAGDDTVSFVVTVSEAPVRIVSSNEETPHTYVAGQRVELWCQLSRAEAPVRWYKDGEEVEEGESLVLEREGPRCRLVLPCARLQDTGEFICDTGDAAVSYHIMVAEPRVRILHPAQRSLELPVLAPGHVELRCELSVPDAAVRWFKDGLEVDETHNLRLLADGAWRCLLIPRSSAEDTGEYICESKDEAVSFDVKVTEPPVKILQPQRPPPVVKVSPGETVTLSCELSRPDAPVCWAREGVRLEAGGSWVLEEEGAHRRLLIPAARAEHAGKYLCDAADDAVTFTVQVSDPPVRILERDALPTCRRCRAMEDLVLEVQLSHAHGEVKWYKDGEKLQDTGHVRLEEDGQRRALVILGATGRDAGEYLCDTHDDSVIFCVTVEAPEPPVRIVGNTGTAEHRCLVAGQDLVLACELSQPDAAVRWLRDGRELQPGERVCIVARGALRELTVRGAQPGDSGCYVCDAASDRMVTSVEVTAQAVRIVNKEEAQSPLEVQEGDSVTLVAQLSPETAAAQWQKDGQMLLSGGRLLVCSEGPARSLTIKQVELGDAGTFLCDAGDDEVYFTLHVKEAPVLFVNKQEEREKLLVLEGGSAVLSAVVSKEQADVTWLCPRQLAVPSERCQLRCDGRVHSLVLSNVAKEDAGVYTCLSPDDQMQFDISVRELQVKFLRGLSDVRARRGETVVLWCELCKAHGDVVWLKDGRVLEPDARREVRVQGRERSLVLSCVGPEDAGEYCCESNDDRTLATLTVQVRRVVEIIAELQSLMVLEGDDATFKCMVSPEDVVVTWQLDGRPVVPSERLQVARSGLCHSLTVRGCQPSDAATVTANAEGLLSTARLSVQEAQVLFVRKLRDVVAEEQQDVCLEVEVSHEAAEVQWLKQGVLLQPGDKYLMRESGCRRTLTIRSVSPSDRGTYRCESLHDRTQGKLSVEPQKVSIRRPLADVETFEKQTATFLLELSHAGVPGVWTHGGVRVKPSATCRVSATGCTHSLTLEGLALEDSGTITFTADTLRCSARLLVREPPVSMLKLLQDLEVPEAGAATFECELSRPSAEVKWLKDGMELRPGPHCRMYSAGRRRLLQLSRCALPDAGIYTCEAGDCQASATLRVHEHQVHVVQELQDACVQEGDNAVFTCEVSHGDVVGEWFRDGEKIKVSSTVKIRQEGTRHFLLLYSVRPEDAGAIRFAARTASSEASLQVEVLPIRIVKPLRDKTVLARHKATLECTVSHARGRVRWLRGDTEIFAGDKYEICNLDCYRTLIIHRVGPEDEDSYTCDAFDDRSTARLLVEGS", "length": 2245, "header": "tr|A0A8V0ZIA1-1|A0A8V0ZIA1_CHICK Isoform 1 of Obscurin like cytoskeletal adaptor 1 OS=Gallus gallus OX=9031 GN=OBSL1 PE=3 SV=1 CANONICAL=A0A8V0ZIA1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1/entry#A0A8V0ZIA1-1", "sequence": { "sequence": "MESHGAAPRFLAYPRAFTAQSGTDAMLRCQIAGDPRPSVLWEKDTAPIHPSGRFCMEAEGDMYSLRVSCVTPQDGGLYVCKAKNCVGETYAAATLRVEAEEHQQEEEEEEGRAGGRAPTFLVGPTSVRVCRGEDVTFSCRVLGQPCPLLEWEKDGHRLRDLFESSHFAVGRQPEDWHYLKLFGVRPPDAGVYVCRARSGSKEALAAAVLLVEPRCSPSDSTQPRRLRHACTDTWAPAPNGTPRAKAFAVSAGKHAKFRCYVTGKPKPEIIWQKDGKAVAPGRRHLIYEDREGYFILKVLYCRPRDQGLYVCTASNTAGQTLSAVQLQVKEHRLRFQVPLEDVEVAEREDAVLECQVPLGSIPTAWFLEDRELQPSHKYVMEECGVVRRLTIRDARTDDDGIYLCQMKDRGRSIAEVSVRGLIVKRLPRKLDVMEGENAAFCVETQEAVEGISWTRNGLQLHESPRAVLKSFGRTHLLVLVHVTREDAGIICFSVGESLTSSQLRVKCVKRDPPGVPMAAQLSTEQSNAALLTWCPAPDVHHRPPSAYIVERREAAGGSWVQCLSTELPGRVQVLGDSVPREADYCFRVCAVNKHGRSDPVEFPGCVHLVPAVHLERGLQDARVRDGEDARFSVELSASVQGEWFLNGTRLQSEESGRFSVQHCGTEHSLLIRSARLRESGARITFVASSVRDSAILHVQAPQARIAPVPEARRLRELLAGLPLLLECEVSPAGVPVCWLKDGEAVVPSESLGIQSEGCWRRLHIPTAVPSDSGTYTCDAGDDTVSFVVTVSEAPVRIISSNEETPHTYMAGQRVELWCQLSHAEAPVRWYKDGEEVEEGESLVLEREGPRCRLVLPCACPQDTGEFVCDVGGDSVFYTITVAAPQARIAPVPEAQQLRELLAGLPLLLECEVSPAGAPVRWLKDGEAVVPSESLGIQAEGCWRRLHIPTAVPSDSGTYTCDAGDDTVSFVVTVSEAPVRIVSSNEETPHTYVAGQRVELWCQLSRAEAPVRWYKDGEEVEEGESLVLEREGPRCRLVLPCARLQDTGEFICDTGDAAVSYHIMVAEPRVRILHPAQRSLELPVLAPGHVELRCELSVPDAAVRWFKDGLEVDETHNLRLLADGAWRCLLIPRSSAEDTGEYICESKDEAVSFDVKVTEPPVKILQPQRPPPVVKVSPGETVTLSCELSRPDAPVCWAREGVRLEAGGSWVLEEEGAHRRLLIPAARAEHAGKYLCDAADDAVTFTVQVSDPPVRILERDALPTCRRCRAMEDLVLEVQLSHAHGEVKWYKDGEKLQDTGHVRLEEDGQRRALVILGATGRDAGEYLCDTHDDSVIFCVTVEAPEPPVRIVGNTGTAEHRCLVAGQDLVLACELSQPDAAVRWLRDGRELQPGERVCIVARGALRELTVRGAQPGDSGCYVCDAASDRMVTSVEVTAQAVRIVNKEEAQSPLEVQEGDSVTLVAQLSPETAAAQWQKDGQMLLSGGRLLVCSEGPARSLTIKQVELGDAGTFLCDAGDDEVYFTLHVKEAPVLFVNKQEEREKLLVLEGGSAVLSAVVSKEQADVTWLCPRQLAVPSERCQLRCDGRVHSLVLSNVAKEDAGVYTCLSPDDQMQFDISVRELQVKFLRGLSDVRARRGETVVLWCELCKAHGDVVWLKDGRVLEPDARREVRVQGRERSLVLSCVGPEDAGEYCCESNDDRTLATLTVQVRRVVEIIAELQSLMVLEGDDATFKCMVSPEDVVVTWQLDGRPVVPSERLQVARSGLCHSLTVRGCQPSDAATVTANAEGLLSTARLSVQEAQVLFVRKLRDVVAEEQQDVCLEVEVSHEAAEVQWLKQGVLLQPGDKYLMRESGCRRTLTIRSVSPSDRGTYRCESLHDRTQGKLSVEPQKVSIRRPLADVETFEKQTATFLLELSHAGVPGVWTHGGVRVKPSATCRVSATGCTHSLTLEGLALEDSGTITFTADTLRCSARLLVREPPVSMLKLLQDLEVPEAGAATFECELSRPSAEVKWLKDGMELRPGPHCRMYSAGRRRLLQLSRCALPDAGIYTCEAGDCQASATLRVHEHQVHVVQELQDACVQEGDNAVFTCEVSHGDVVGEWFRDGEKIKVSSTVKIRQEGTRHFLLLYSVRPEDAGAIRFAARTASSEASLQVEVLPIRIVKPLRDKTVLARHKATLECTVSHARGRVRWLRGDTEIFAGDKYEICNLDCYRTLIIHRVGPEDEDSYTCDAFDDRSTARLLVEGS", "length": 2245, "header": "tr|A0A8V0ZIA1-1|A0A8V0ZIA1_CHICK Isoform 1 of Obscurin like cytoskeletal adaptor 1 OS=Gallus gallus OX=9031 GN=OBSL1 PE=3 SV=1 CANONICAL=A0A8V0ZIA1-1" }, "locus": { "chromosome": "7", "start_pos": 21693755, "end_pos": 21682367, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051325.1", "url": "https://www.ensembl.org/id/ENSGALT00010051325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030516.1", "url": "https://www.ensembl.org/id/ENSGALP00010030516.1" } ] } }, { "isoform_ac": "A0A8V0ZP85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1/entry#A0A8V0ZP85-1", "sequence": { "sequence": 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"length": 2062, "header": "tr|A0A8V0ZP85-1|A0A8V0ZP85_CHICK Computationally mapped isoform of Obscurin like cytoskeletal adaptor 1 OS=Gallus gallus OX=9031 GN=OBSL1 PE=3 SV=1 CANONICAL=A0A8V0ZIA1-1" }, "locus": { "chromosome": "7", "start_pos": 21693755, "end_pos": 21682367, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051322.1", "url": "https://www.ensembl.org/id/ENSGALT00010051322.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030513.1", "url": "https://www.ensembl.org/id/ENSGALP00010030513.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 125, "start_aa": "Thr", "end_pos": 125, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr125", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" }, { "name": "3M complex", "id": "GO:1990393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of dendrite morphogenesis", "id": "GO:0050775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050775", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" }, { "name": "protein localization to Golgi apparatus", "id": "GO:0034067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034067", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 646, "end_pos": 648, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA1" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 515, 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"expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA6", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZIA6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIA6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24327", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24327", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24327:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24327:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZIA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYIMSDVASDIVFLFSDVSSASSSSGNFSQFMPDLATSQHSASSSPQLTTKSQISHGEREYHMGTVKKAKSCTAFSQEQQQILHQLLQSQKYLSPHQIQELAAVKTWFQNQRMKMKRCQKNTLWTAWIRCFMQNSFQPNSYLDVYPEFHQGYTITEASNIQTMPTPCQHYRAGQNAYPIVTSNDGGVFYKGGGTCSIQQTVSFIAQHKVDFYHSYPGSVEYSCTKTNDGYNFHQSAPMGASFPATASHQLYHF", "length": 253, "header": "tr|A0A8V0ZIA6-1|A0A8V0ZIA6_CHICK Isoform 1 of Homeobox domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZIA6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA6/entry#A0A8V0ZIA6-1", "sequence": { "sequence": "MYIMSDVASDIVFLFSDVSSASSSSGNFSQFMPDLATSQHSASSSPQLTTKSQISHGEREYHMGTVKKAKSCTAFSQEQQQILHQLLQSQKYLSPHQIQELAAVKTWFQNQRMKMKRCQKNTLWTAWIRCFMQNSFQPNSYLDVYPEFHQGYTITEASNIQTMPTPCQHYRAGQNAYPIVTSNDGGVFYKGGGTCSIQQTVSFIAQHKVDFYHSYPGSVEYSCTKTNDGYNFHQSAPMGASFPATASHQLYHF", "length": 253, "header": "tr|A0A8V0ZIA6-1|A0A8V0ZIA6_CHICK Isoform 1 of Homeobox domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZIA6-1" }, "locus": { "chromosome": "1", "start_pos": 75871384, "end_pos": 75868960, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052026.1", "url": "https://www.ensembl.org/id/ENSGALT00010052026.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031055.1", "url": "https://www.ensembl.org/id/ENSGALP00010031055.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA6" }, { "id": "SM00389", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 122, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIA9-1", "uniprot_ac": "A0A8V0ZIA9", "uniprot_id": "A0A8V0ZIA9_CHICK", "mass": { "chemical_mass": 199122.0, "monoisotopic_mass": 199122.0 }, "refseq": { "ac": "NP_001182529", "name": "zinc finger SWIM domain-containing protein 8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182529" }, "gene_names": [ { "name": "ZSWIM8", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9" } ] }, { "name": "ZSWIM8", "type": "synonym", "evidence": [ { "id": "NP_001182529", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182529" } ] } ], "protein_names": [ { "name": "Zinc finger SWIM-type containing 8", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger SWIM domain-containing protein 8", "type": "synonym", "evidence": [ { "id": "NP_001182529", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182529" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000231.1. On or before Oct 4, 2021 this sequence version replaced XP_015143705.2, NP_001182529.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001182529", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182529" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZSWIM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9", "locus": { "chromosome": "6", "start_pos": 16600081, "end_pos": 16661356, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021182", "url": "https://www.ensembl.org/id/ENSGALG00010021182" } ] } } ], "crossref": [ { "id": "423739", "url": "https://www.ncbi.nlm.nih.gov/gene/423739", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057945", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057945", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423739", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423739", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR22619", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22619", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22619:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22619:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25572", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25572", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001182529", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001182529", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELMFAEWEDGERFSFEDSDHFEEDSLCSFISEAESLCQNWRGWRKQSAGPNSPTVKMKDGLVIPLVELSAKQVAFHIPFEVVEKVYPPVPEQLQLRIAFWSFPENEEDIRLYSCLANGSADEFQRGEQLFRVRAVKDPLQIGFHLSATVVPPQMMSPKGAYNVAVMFDRCRITSCSCTCGAGAKWCAHVVALCLFRIHNASAVCLRAPVSESLSRLQRDQLQKFAQYLISELPQQILPTAQRLLDELLSSQSTAINTVCGAPDPTAGPSASDQSTWYLDESTLSDNIKKTLHKFCGPSPVVFSDVNSMYLSSTEPPAAAEWACLLRPLRGREPEGIWNLLSIVREMFKRRDSNAAPLLEILTDQCLNYEQITGWWYSVRTSASHSSASGHTGRSNGQSEVAAHACASMCDEMVVLWRLAVLDPTISPQRRRDLCSQLRQWQLKVIDNVKRGQHKKSLEKLFQGFKPAVEACYFNWEEAYPIPGITYSSTDKKNSFCWVKAIQQRSCRLQCAETACEAGRAHGQEPGGPCLQPGDRLRPSPQEPAVRPKELTGKRKVVSETPQRVLRRLSAEGDKAVYKTAVSKAKLPVSKGLTSKHSGKRRMSSEDSSLEPDLAEMSLDDSSLALGAEASNTFSFTESPLSRSYRDAFEEDGGVYFSEGPEPSVRSSSTTKKSTKDPVGEMGSGDDDLTSADENSGGVSLKPEEVGENGAAGGGDDGEEEDDYQVYYLNPQEVAKEDDDKAEGGNEEEQDIFAGIKPLEQENRMEILFACAEALYAHGYSNEACRLTVELARDLLANPPDLKVEQPPTKGKKNKVSTSKQTWMATNTLSKAAFLLTVLSERLEYHNLAFRIGMFALELQRPPASTKALEVKLAYQESEIAALLKKIPLVTNEMNTIRGRAEELREGTLCDYRPVLPLMLASFIFDVLCTPVVSPTGCRPPSRNWNNEMPGDEELGFEAAVAALGMKTTVSEAEHPLLCEGTRREKGDLALALMITYKDDQSKLKKILDKLLDRESQTHKPQTLSSFYSSSKPTVANQKSPSKHAAQSAAAIQQLPGTSVAQQAGVSPAVQSSPETFVEKSSQECSQRSPCEPAGESTVLKQEGKVPSRLALGNRGGYNGRCWGSPVRQKKKHTGMASIDSSAPETTSDSSPTLSRRPLRGGWATTSWGRGQDSDSISSSSSDSLGSSSSSGSRRASGGARAKTVEVGRYKGRRLESHAPHVPNQPSEAAAHFYFELAKTVLIKAGGNSSTSIFTHPSSSGGHQGPHRNLHLCAFEIGLYALGLHNFVSPNWLSRTYSSHVSWITGQAMEIGSAALNILVECWDGHLTPPEVASLADRASRARDSNMVRAAAELALSCLPHAHALNPNEIQRALVQCKEQDNLMLEKACMAVEEAAKGGGVYPEVLFEVAHQWYWLYEQIVGGTPAQREGATGCSASGARAASEAARGLTDNRVTTEPTTVTVAAAVTAAATVMPVISMGSTMYQQHTMAGPAMAHTHTQGLHPYTTLQTHIPCNPQYIGHTIQHMPRPAVFPVPGSAYPQSVHPAFIGAQYPYSVTTPSLAATAVSFPGVPVPSMTQIAVHPYHSETGLSLSSNVAIGSVHAGSTFPAIQGASLTSLSSQPNSLVTGGFPAEDEQHSQPVSPQGLHYLHSAYQVGMLALEMLGRRTQSDHPNNFSRSPPYTEDVKWLLGLAAKLGVNYVHQFCVGAAKGVLNPFVLQDIIMEALQRLNPAHVHNHLRTPAFHQLVQRCQQVYLQYIHYRLIHLAPADYDDFVNAIRSARSAFCLTPVGMMQFNDILQNLKRGKQTKDLWQRVSLEMTTFSP", "length": 1822, "header": "tr|A0A8V0ZIA9-1|A0A8V0ZIA9_CHICK Isoform 1 of Zinc finger SWIM-type containing 8 OS=Gallus gallus OX=9031 GN=ZSWIM8 PE=4 SV=1 CANONICAL=A0A8V0ZIA9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9/entry#A0A8V0ZIA9-1", "sequence": { "sequence": "MELMFAEWEDGERFSFEDSDHFEEDSLCSFISEAESLCQNWRGWRKQSAGPNSPTVKMKDGLVIPLVELSAKQVAFHIPFEVVEKVYPPVPEQLQLRIAFWSFPENEEDIRLYSCLANGSADEFQRGEQLFRVRAVKDPLQIGFHLSATVVPPQMMSPKGAYNVAVMFDRCRITSCSCTCGAGAKWCAHVVALCLFRIHNASAVCLRAPVSESLSRLQRDQLQKFAQYLISELPQQILPTAQRLLDELLSSQSTAINTVCGAPDPTAGPSASDQSTWYLDESTLSDNIKKTLHKFCGPSPVVFSDVNSMYLSSTEPPAAAEWACLLRPLRGREPEGIWNLLSIVREMFKRRDSNAAPLLEILTDQCLNYEQITGWWYSVRTSASHSSASGHTGRSNGQSEVAAHACASMCDEMVVLWRLAVLDPTISPQRRRDLCSQLRQWQLKVIDNVKRGQHKKSLEKLFQGFKPAVEACYFNWEEAYPIPGITYSSTDKKNSFCWVKAIQQRSCRLQCAETACEAGRAHGQEPGGPCLQPGDRLRPSPQEPAVRPKELTGKRKVVSETPQRVLRRLSAEGDKAVYKTAVSKAKLPVSKGLTSKHSGKRRMSSEDSSLEPDLAEMSLDDSSLALGAEASNTFSFTESPLSRSYRDAFEEDGGVYFSEGPEPSVRSSSTTKKSTKDPVGEMGSGDDDLTSADENSGGVSLKPEEVGENGAAGGGDDGEEEDDYQVYYLNPQEVAKEDDDKAEGGNEEEQDIFAGIKPLEQENRMEILFACAEALYAHGYSNEACRLTVELARDLLANPPDLKVEQPPTKGKKNKVSTSKQTWMATNTLSKAAFLLTVLSERLEYHNLAFRIGMFALELQRPPASTKALEVKLAYQESEIAALLKKIPLVTNEMNTIRGRAEELREGTLCDYRPVLPLMLASFIFDVLCTPVVSPTGCRPPSRNWNNEMPGDEELGFEAAVAALGMKTTVSEAEHPLLCEGTRREKGDLALALMITYKDDQSKLKKILDKLLDRESQTHKPQTLSSFYSSSKPTVANQKSPSKHAAQSAAAIQQLPGTSVAQQAGVSPAVQSSPETFVEKSSQECSQRSPCEPAGESTVLKQEGKVPSRLALGNRGGYNGRCWGSPVRQKKKHTGMASIDSSAPETTSDSSPTLSRRPLRGGWATTSWGRGQDSDSISSSSSDSLGSSSSSGSRRASGGARAKTVEVGRYKGRRLESHAPHVPNQPSEAAAHFYFELAKTVLIKAGGNSSTSIFTHPSSSGGHQGPHRNLHLCAFEIGLYALGLHNFVSPNWLSRTYSSHVSWITGQAMEIGSAALNILVECWDGHLTPPEVASLADRASRARDSNMVRAAAELALSCLPHAHALNPNEIQRALVQCKEQDNLMLEKACMAVEEAAKGGGVYPEVLFEVAHQWYWLYEQIVGGTPAQREGATGCSASGARAASEAARGLTDNRVTTEPTTVTVAAAVTAAATVMPVISMGSTMYQQHTMAGPAMAHTHTQGLHPYTTLQTHIPCNPQYIGHTIQHMPRPAVFPVPGSAYPQSVHPAFIGAQYPYSVTTPSLAATAVSFPGVPVPSMTQIAVHPYHSETGLSLSSNVAIGSVHAGSTFPAIQGASLTSLSSQPNSLVTGGFPAEDEQHSQPVSPQGLHYLHSAYQVGMLALEMLGRRTQSDHPNNFSRSPPYTEDVKWLLGLAAKLGVNYVHQFCVGAAKGVLNPFVLQDIIMEALQRLNPAHVHNHLRTPAFHQLVQRCQQVYLQYIHYRLIHLAPADYDDFVNAIRSARSAFCLTPVGMMQFNDILQNLKRGKQTKDLWQRVSLEMTTFSP", "length": 1822, "header": "tr|A0A8V0ZIA9-1|A0A8V0ZIA9_CHICK Isoform 1 of Zinc finger SWIM-type containing 8 OS=Gallus gallus OX=9031 GN=ZSWIM8 PE=4 SV=1 CANONICAL=A0A8V0ZIA9-1" }, "locus": { "chromosome": "6", "start_pos": 16661238, "end_pos": 16601402, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051339.1", "url": "https://www.ensembl.org/id/ENSGALT00010051339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030530.1", "url": "https://www.ensembl.org/id/ENSGALP00010030530.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1424, "start_aa": "Thr", "end_pos": 1424, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1424", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1468, "start_aa": "Thr", "end_pos": 1468, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1468", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 266, "start_aa": "Thr", "end_pos": 266, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr266", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423739", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423739", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9" } ], "pmid": "" }, { "name": "Cul2-RING ubiquitin ligase complex", "id": "GO:0031462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of miRNA catabolic process", "id": "GO:2000627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000627", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIA9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1248, "end_pos": 1250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1674, "end_pos": 1676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA9" }, { "id": "PS50966", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50966" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SWIM-type", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 198, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 266, 1424, 1468 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 1248, "end_pos": 1250 }, { "start_pos": 1674, "end_pos": 1676 }, { "start_pos": 200, "end_pos": 202 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIC0-1", "uniprot_ac": "A0A8V0ZIC0", "uniprot_id": "A0A8V0ZIC0_CHICK", "mass": { "chemical_mass": 96208.0, "monoisotopic_mass": 96208.0 }, "refseq": { "ac": "XP_414374", "name": "zinc finger protein ZXDC", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414374" }, "gene_names": [ { "name": "ZXDC", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0" } ] }, { "name": "ZXDC", "type": "synonym", "evidence": [ { "id": "XP_414374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414374" } ] } ], "protein_names": [ { "name": "ZXD family zinc finger C", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein ZXDC", "type": "synonym", "evidence": [ { "id": "XP_414374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414374" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_414374.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414374" } ] }, { "annotation": "Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0#function" }, { "database": "UniProtKB", "id": "ARBA00053079", "url": "https://www.uniprot.org/uniprotkb/ARBA00053079#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZXDC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZIC0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "416034", "url": "https://www.ncbi.nlm.nih.gov/gene/416034", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416034", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416034", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LICQYIF", "url": "https://omabrowser.org/oma/group/LICQYIF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIC0", "url": "https://www.orthodb.org/?gene=A0A8V0ZIC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414374", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METQGLPAAEAARARPGAQHGGPAAPPAAPGRPPPPPDWDPAASAAAASSAASSAASGLYVSFPVLLVEEKPEPGAGPAPSPSAPPAGPAPDSDGLLLVLNVVRGNAEPGSGDGEAGRAQPGPPPAEPPEEGPGSAPPPPPPPPPPPPPPRDGDGDGGAEDGSFSGTITINNQSLVVRIENGVLTLGPGAEQAASTAPPPAPPPPPAGPAEPPPGVPRPRSPPAFPCPEPRCGEAFPRKQQLRLHRLTAHGGGGEDSRGAPAAGGAARPFGCPVPGCAWSFATAYKLRRHLHSHDKLRPFACAAPGCSKRFTTVYNLRAHSRAHEQEAAHKCEACGQRFPSAARLAAHRRRSHLEPERPYRCDFPGCERTFITVSALFSHNRAHFREQEQFSCSFPGCNKQYDKACRLKIHMRSHTGERPFICDFEGCGWSFTSMSKLLRHKRKHEDDRRFTCPVEGCGKSFTRAEHLKGHSITHLGTKPFECPVEGCCAKFSARSSLYIHSKKHLQDVDSLKTRCPVSSCNKLFTSKHSMKTHMVKQHNFSPDLLTQLEATSSLTPSSELTSPGHSDLSNIDLVSLFSNVSSNNSGISADMALVNSGIVTIDVASVGSTLGGNLPVSSSSLSQAVDPLILVASSDMPQSLDSSLLLGTGTTVLQQSTLNLDDVQTVNAEALGSLASLSVRNPSQDVHGLTSSNNLTIDTATLTPSSSLGGTNVPELLTPTKMERNLLPSSDVVGQQEGSKVVTQFVFSNPPGSYSAQKEMDLSTMTGSSFLESSGSARTDYRAIQLAKKRKQKGNGSSTGTPGSGQRKSKGGKVSPTSFSSSAPGGRLGGNAVLPNGGLTIRDPATGAQYVQIQLLQDDPSGEGDLPFQLSSQSSSSHSQLTVDLPVHILQEPHNSAEDDAGSDNSQFTGSTINLQDLE", "length": 920, "header": "tr|A0A8V0ZIC0-1|A0A8V0ZIC0_CHICK Isoform 1 of ZXD family zinc finger C OS=Gallus gallus OX=9031 GN=ZXDC PE=3 SV=1 CANONICAL=A0A8V0ZIC0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0/entry#A0A8V0ZIC0-1", "sequence": { "sequence": "METQGLPAAEAARARPGAQHGGPAAPPAAPGRPPPPPDWDPAASAAAASSAASSAASGLYVSFPVLLVEEKPEPGAGPAPSPSAPPAGPAPDSDGLLLVLNVVRGNAEPGSGDGEAGRAQPGPPPAEPPEEGPGSAPPPPPPPPPPPPPPRDGDGDGGAEDGSFSGTITINNQSLVVRIENGVLTLGPGAEQAASTAPPPAPPPPPAGPAEPPPGVPRPRSPPAFPCPEPRCGEAFPRKQQLRLHRLTAHGGGGEDSRGAPAAGGAARPFGCPVPGCAWSFATAYKLRRHLHSHDKLRPFACAAPGCSKRFTTVYNLRAHSRAHEQEAAHKCEACGQRFPSAARLAAHRRRSHLEPERPYRCDFPGCERTFITVSALFSHNRAHFREQEQFSCSFPGCNKQYDKACRLKIHMRSHTGERPFICDFEGCGWSFTSMSKLLRHKRKHEDDRRFTCPVEGCGKSFTRAEHLKGHSITHLGTKPFECPVEGCCAKFSARSSLYIHSKKHLQDVDSLKTRCPVSSCNKLFTSKHSMKTHMVKQHNFSPDLLTQLEATSSLTPSSELTSPGHSDLSNIDLVSLFSNVSSNNSGISADMALVNSGIVTIDVASVGSTLGGNLPVSSSSLSQAVDPLILVASSDMPQSLDSSLLLGTGTTVLQQSTLNLDDVQTVNAEALGSLASLSVRNPSQDVHGLTSSNNLTIDTATLTPSSSLGGTNVPELLTPTKMERNLLPSSDVVGQQEGSKVVTQFVFSNPPGSYSAQKEMDLSTMTGSSFLESSGSARTDYRAIQLAKKRKQKGNGSSTGTPGSGQRKSKGGKVSPTSFSSSAPGGRLGGNAVLPNGGLTIRDPATGAQYVQIQLLQDDPSGEGDLPFQLSSQSSSSHSQLTVDLPVHILQEPHNSAEDDAGSDNSQFTGSTINLQDLE", "length": 920, "header": "tr|A0A8V0ZIC0-1|A0A8V0ZIC0_CHICK Isoform 1 of ZXD family zinc finger C OS=Gallus gallus OX=9031 GN=ZXDC PE=3 SV=1 CANONICAL=A0A8V0ZIC0-1" }, "locus": { "chromosome": "12", "start_pos": 10861652, "end_pos": 10852448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051345.1", "url": "https://www.ensembl.org/id/ENSGALT00010051345.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030536.1", "url": "https://www.ensembl.org/id/ENSGALP00010030536.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 802, "start_aa": "Thr", "end_pos": 802, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr802", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416034", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416034", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RTP5-1", "protein_name": "C2H2-type domain-containing protein", "gene_name": "LOC110258620", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEIPRLLPARGTRQGGGAGSPGGGGRIHGGPDPRAGQAPARRLLLLRGPQDGGSGRRREEARAASSGPGQSPSAPRPDRGSGGGGSGGGDDFFLVLLDPVGGDVETAGAGQAAGPVWREEAGLGPRLQGGESGANPEGRPALGPSCLSVIPAPVPALAPIPAPGLGPAAAFAGTVTIHNQNLLLRLENGVLTLATPPPPAWAPGVAPTPQPRGLIAPQAGIPHAAQPGDCPELPPDLLLAERAEPAPAPAPEAEAEGPAAAESPRGPPGPGQGVVLYLCPEAQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEETFPTQAKLSAHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFEGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVEGCCARFSARSSLYIHSKKHLQDVDTWKSRCPVSTCNKLFTSKHSMKTHMAKRHNLRQDLLAQLEAANSLTPSSELTSQGQNDLSEAELVSLFSDAPGNSSAAVLDTALVNSGILTIDVASVNSTLAGNHVPASNNNSLGQAVDPPALMATGDLPQSLDTSLFFGTTAAGFQQSPLDMDDVSTLSVGTLGSLGSLAMKNSSQEPQALTPSSKLTADTDALTPSSTLCESSVSELLPPTKTEWNVHPDSDFFGQEEETQFGFSNPAGNHGSQKETDLITVTGSSFLV", "length": 810 }, "evidence": [ { "id": "A0A8V0ZIC0", "url": "https://omabrowser.org/oma/group/A0A8V0ZIC0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P98169-1", "protein_name": "Zinc finger X-linked protein ZXDB", "gene_name": "ZXDB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEIPKLLPARGTLQGGGGGGIPAGGGRVHRGPDSPAGQVPTRRLLLLRGPQDGGPGRRREEASTASRGPGPSLLAPRTDQPSGGGGGGGDDFFLVLLDPVGGDVETAGSGQAAGPVLREEAEEGPGLQGGESGANPAGPTALGPRCLSAVPTPAPISAPGPAAAFAGTVTIHNQDLLLRFENGVLTLATPPPHAWEPGAAPAQQPGCLIAPQAGFPHAAHPGDCPELPPDLLLAEPAEPAPAPAPEEEAEGPAAALGPRGPLGSGPGVVLYLCPEAQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEESFPTQAKLSAHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFDGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVAGCCARFSARSSLYIHSKKHLQDVDTWKSRCPISSCNKLFTSKHSMKTHMVKRHKVGQDLLAQLEAANSLTPSSELTSQRQNDLSDAEIVSLFSDVPDSTSAALLDTALVNSGILTIDVASVSSTLAGHLPANNNNSVGQAVDPPSLMATSDPPQSLDTSLFFGTAATGFQQSSLNMDEVSSVSVGPLGSLDSLAMKNSSPEPQALTPSSKLTVDTDALTPSSTLCENSVSELLTPTKAEWNVHPDSDFFGQEGETQFGFPNAAGNHGSQKETDLITVTGSSFLV", "length": 803 }, "evidence": [ { "id": "A0A8V0ZIC0", "url": "https://omabrowser.org/oma/group/A0A8V0ZIC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0" } ], "pmid": "" }, { "name": "C2H2 zinc finger domain binding", "id": "GO:0070742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070742", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 695, "end_pos": 697, "annotation": "n_glycosylation_sequon" }, { "start_pos": 796, "end_pos": 798, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 225, "end_pos": 255, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 802 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 540, "end_pos": 542 }, { "start_pos": 580, "end_pos": 582 }, { "start_pos": 584, "end_pos": 586 }, { "start_pos": 695, "end_pos": 697 }, { "start_pos": 796, "end_pos": 798 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZID8-1", "uniprot_ac": "A0A8V0ZID8", "uniprot_id": "A0A8V0ZID8_CHICK", "mass": { "chemical_mass": 28612.0, "monoisotopic_mass": 28612.0 }, "refseq": { "ac": "NP_001264426", "name": "DNA oxidative demethylase ALKBH2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264426" }, "gene_names": [ { "name": "ALKBH2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZID8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ] }, { "name": "ALKBH2", "type": "synonym", "evidence": [ { "id": "NP_001264426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264426" } ] } ], "protein_names": [ { "name": "DNA oxidative demethylase ALKBH2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZID8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8/entry#names_and_taxonomy" } ] }, { "name": "1.14.11.33", "type": "synonym", "evidence": [ { "id": "A0A8V0ZID8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8/entry#names_and_taxonomy" } ] }, { "name": "Alkylated DNA repair protein alkB homolog 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZID8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8/entry#names_and_taxonomy" } ] }, { "name": "Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZID8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8/entry#names_and_taxonomy" } ] }, { "name": "DNA oxidative demethylase ALKBH2 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001264426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264426" } ] }, { "name": "alkB, alkylation repair homolog 2", "type": "synonym", "evidence": [ { "id": "NP_001264426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264426" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BU400522.1, SRR12888536.24437.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06140853 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. On Oct 6, 2021 this sequence version replaced NP_001264426.1. Transcript Variant: This variant (1) encodes the longest isoform (1).", "evidence": [ { "database": "RefSeq", "id": "NP_001264426", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264426" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZID8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALKBH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8", "locus": { "chromosome": "15", "start_pos": 6663100, "end_pos": 6665585, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021476", "url": "https://www.ensembl.org/id/ENSGALG00010021476" } ] } } ], "crossref": [ { "id": "A0A8V0ZID8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZID8", "database": "AlphaFoldDB", "categories": [] }, { "id": "416897", "url": "https://www.ncbi.nlm.nih.gov/gene/416897", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032852", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032852", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TQHHWQH", "url": "https://omabrowser.org/oma/group/TQHHWQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZID8", "url": "https://www.orthodb.org/?gene=A0A8V0ZID8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJW6", "url": "https://www.orthodb.org/?gene=A0A8V0ZJW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJX1", "url": "https://www.orthodb.org/?gene=A0A8V0ZJX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31573", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31573", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31573:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31573:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264426", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264426", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "30299", "url": "https://www.rhea-db.org/rhea/30299", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70435", "url": "https://www.rhea-db.org/rhea/70435", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70439", "url": "https://www.rhea-db.org/rhea/70439", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70443", "url": "https://www.rhea-db.org/rhea/70443", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70447", "url": "https://www.rhea-db.org/rhea/70447", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70459", "url": "https://www.rhea-db.org/rhea/70459", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70463", "url": "https://www.rhea-db.org/rhea/70463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70467", "url": "https://www.rhea-db.org/rhea/70467", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70471", "url": "https://www.rhea-db.org/rhea/70471", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70487", "url": "https://www.rhea-db.org/rhea/70487", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZID8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZID8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRFVVKRSAEEPGGDGKKPRLEEEAGGLPHPSQPSQEIRAQGLSLEYRLLFGRAEADAIFQQLEKEVEYFEGEQTKLHVFGKWHNIPRKQVTYGDPELTYTYSGVTFSPKPWIPVLNHIRDRLVLETGHTFNFVVINRYKDGEDHIGEHRDDEKELVPRSPIASVSFGACRDFVFRHCDSRGKNATRHIKPIRLQLAHGSLLMMKYPTNVYWYHSLPIRRRVLAPRINLTFRKMMAVDKKESILTT", "length": 247, "header": "tr|A0A8V0ZID8-1|A0A8V0ZID8_CHICK Isoform 1 of DNA oxidative demethylase ALKBH2 OS=Gallus gallus OX=9031 GN=ALKBH2 PE=3 SV=1 CANONICAL=A0A8V0ZID8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZID8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8/entry#A0A8V0ZID8-1", "sequence": { "sequence": "MDRFVVKRSAEEPGGDGKKPRLEEEAGGLPHPSQPSQEIRAQGLSLEYRLLFGRAEADAIFQQLEKEVEYFEGEQTKLHVFGKWHNIPRKQVTYGDPELTYTYSGVTFSPKPWIPVLNHIRDRLVLETGHTFNFVVINRYKDGEDHIGEHRDDEKELVPRSPIASVSFGACRDFVFRHCDSRGKNATRHIKPIRLQLAHGSLLMMKYPTNVYWYHSLPIRRRVLAPRINLTFRKMMAVDKKESILTT", "length": 247, "header": "tr|A0A8V0ZID8-1|A0A8V0ZID8_CHICK Isoform 1 of DNA oxidative demethylase ALKBH2 OS=Gallus gallus OX=9031 GN=ALKBH2 PE=3 SV=1 CANONICAL=A0A8V0ZID8-1" }, "locus": { "chromosome": "15", "start_pos": 6665468, "end_pos": 6663332, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052078.1", "url": "https://www.ensembl.org/id/ENSGALT00010052078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031090.1", "url": "https://www.ensembl.org/id/ENSGALP00010031090.1" } ] } }, { "isoform_ac": "A0A8V0ZJW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8/entry#A0A8V0ZJW6-1", "sequence": { "sequence": "MDRFVVKRSAEEPGGDGKKPRLEEEAGGLPHPSQPSQEIRAQGLSLEYRLLFGRAEADAIFQQLEKEVEYFEDIKMVRTT", "length": 80, "header": "tr|A0A8V0ZJW6-1|A0A8V0ZJW6_CHICK Computationally mapped isoform of AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase OS=Gallus gallus OX=9031 GN=ALKBH2 PE=4 SV=1 CANONICAL=A0A8V0ZID8-1" }, "locus": { "chromosome": "15", "start_pos": 6665468, "end_pos": 6664412, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052062.1", "url": "https://www.ensembl.org/id/ENSGALT00010052062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031077.1", "url": "https://www.ensembl.org/id/ENSGALP00010031077.1" } ] } }, { "isoform_ac": "A0A8V0ZJX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8/entry#A0A8V0ZJX1-1", "sequence": { "sequence": "MDRFVVKRSAEEPGGDGKKPRLEEEAGGLPHPSQPSQEIRAQGLSLEYRLLFGRAEADAIFQQLEKEVEYFEGEQTKLHVFAVDPSSQPHQRSACFGNRTYF", "length": 102, "header": "tr|A0A8V0ZJX1-1|A0A8V0ZJX1_CHICK Computationally mapped isoform of AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase OS=Gallus gallus OX=9031 GN=ALKBH2 PE=4 SV=1 CANONICAL=A0A8V0ZID8-1" }, "locus": { "chromosome": "15", "start_pos": 6665468, "end_pos": 6664577, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052070.1", "url": "https://www.ensembl.org/id/ENSGALT00010052070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031082.1", "url": "https://www.ensembl.org/id/ENSGALP00010031082.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K5G5-1", "protein_name": "DNA oxidative demethylase ALKBH2", "gene_name": "Alkbh2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCRALARVAAPDPPVEHGCVPVLAYPAGRRTEAPCFSGTRLWLAGGGGMDRFLVRPDRGDIQGAAEEPAPTGEASGDMQSPGWQHFRAEGLNCDYTVLFRKAEADQIFRELEQEVEYFTGALAKVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLTPKPWIPVLERVRDQVCRVTGQTFNFVLVNRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDILFRHKDSRGKRPRRAVEVVRLQLAHGSLLMMNHPTNTHWYHSLPIRKRVLAPRINLTFRKILPTKK", "length": 287 }, "evidence": [ { "id": "A0A8V0ZID8", "url": "https://omabrowser.org/oma/group/A0A8V0ZID8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8D0NS07-1", "protein_name": "DNA oxidative demethylase ALKBH2", "gene_name": "ALKBH2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDRFLVKGAVGGLWGKREQEQTGGGPAGLGEEEENSRKKPRREGPGNGVDSAGLSWRRIRAEGLDCDYTVLFAKAEADAIFQELEKEVEYFTGALARVQVFGKWHNVPRKQATYGDAGLTYTFSGLTLSPKPWVPVLEHVRDRVSLVTGQTFNFVLVNRYKDGHDHIGEHRDDERELAPGSPIASVSFGACRDFFFRHKDSRGKQPSRRLGVVRLQLAHGSLLMMNHPTNTHWYHSLPVRKKILAPRVNLTFRKILPTTK", "length": 260 }, "evidence": [ { "id": "A0A8V0ZID8", "url": "https://omabrowser.org/oma/group/A0A8V0ZID8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A3QK41-1", "protein_name": "DNA oxidative demethylase ALKBH2", "gene_name": "alkbh2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKFLTRKRKRSSEEPDEWKTEALIKKPTEEEECEEGEEEFSNPIPWQKIEAEGLDCDYSLLFNKEEADHLFNQLEEEVEYFTGDNAKLQVYGKSYNIPRKQATYGDEGLMYSFSGVNLLAKPWTSTLEHIRDAVTKATGYTFNFVLINRYKDGHDHIGEHRDDERELDPACPIASVSLGAARHLIFRHRDARTGPRKRQIEPVKLELANGSLLLMNFPTNTYWYHSLPIRKKVITPRINLTFRRIVKNRQKNGTKTE", "length": 258 }, "evidence": [ { "id": "A0A8V0ZID8", "url": "https://omabrowser.org/oma/group/A0A8V0ZID8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3HI87-1", "protein_name": "DNA oxidative demethylase ALKBH2", "gene_name": "Alkbh2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVQGGGMDRFLVKPDPGDLGAGGEESAPSGGASGGQPSPNWRHLRAQGLNCDYTVLFGKAEADEIFRELEQEVEYFTGALAKVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLTPKPWIPVLERVRDRVCRVTGQSFNFVLINRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFLFRHKDSRGKRPRQTVEVVRLQLAHGSLLMMNHPTNAHWYHSLPIRKKVLAPRVNLTFRKILHTKK", "length": 246 }, "evidence": [ { "id": "A0A8V0ZID8", "url": "https://omabrowser.org/oma/group/A0A8V0ZID8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q58DM4-1", "protein_name": "DNA oxidative demethylase ALKBH2", "gene_name": "ALKBH2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDRFLVKGAVGSLKRRMEQEQTGGGPAGLAEEEGNSKKNPRRAAPGNGVDSAGLTWGRIRAEGLNCDYTILFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDTGLTYTFSGLTLSPKPWIPVLERVRDRVSLVTGQTFNFVLINRYKDGQDHIGEHRDDERELALGSPIASVSFGACRDFVFRHKDSRGKHPSRRLEVVRLQLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILPTTKRTTLLTASASVGSFALHS", "length": 278 }, "evidence": [ { "id": "A0A8V0ZID8", "url": "https://omabrowser.org/oma/group/A0A8V0ZID8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6NS38-1", "protein_name": "DNA oxidative demethylase ALKBH2", "gene_name": "ALKBH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRFLVKGAQGGLLRKQEEQEPTGEEPAVLGGDKESTRKRPRREAPGNGGHSAGPSWRHIRAEGLDCSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILLTKK", "length": 261 }, "evidence": [ { "id": "A0A8V0ZID8", "url": "https://omabrowser.org/oma/group/A0A8V0ZID8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P6J4-1", "protein_name": "DNA oxidative demethylase ALKBH2", "gene_name": "Alkbh2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDKFLVRPDLRDLQGGGEEPAPTGGASGDLKSPDWRHLRAEGLSCDYTVLFGKAEADKIFRELEQEVEYFTGALAKVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLTPKPWVPVLERVRDRVCEVTGQTFNFVLVNRYKDGCDHIGEHRDDERELAPGSPIASVSFGACRDFIFRHKDSRGKRPRRTVEVVRLQLAHGSLLMMNPPTNTHWYHSLPIRKRVLAPRVNLTFRKILPTKK", "length": 239 }, "evidence": [ { "id": "A0A8V0ZID8", "url": "https://omabrowser.org/oma/group/A0A8V0ZID8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SIE0-1", "protein_name": "DNA oxidative demethylase ALKBH2", "gene_name": "ALKBH2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTNPLNSTAANRSNQPSSDGISDGQITNEEAESLINKKNCSGHKLKEVTDSDTFSDNGKDDSDTKKRFHYHQDQRRMSLTSIVAVESPSSSNAPSRKTIDLGHGSDLIYIQRFLPFQQSWTFFDYLDKHIPWTRPTIRVFGRSCLQPRDTCYVASSGLTALVYSGYRPTSYSWDDFPPLKEILDAIYKVLPGSRFNSLLLNRYKGASDYVAWHADDEKIYGPTPEIASVSFGCERDFVLKKKKDEESSQGKTGDSGPAKKRLKRSSREDQQSLTLKHGSLLVMRGYTQRDWIHSVPKRAKAEGTRINLTFRLVL", "length": 314 }, "evidence": [ { "id": "A0A8V0ZID8", "url": "https://omabrowser.org/oma/group/A0A8V0ZID8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZID8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZID8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA alkylation repair", "id": "GO:0006307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZID8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ferrous iron binding", "id": "GO:0008198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZID8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ], "pmid": "" }, { "name": "cytosine C-5 DNA demethylase activity", "id": "GO:0051747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051747", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZID8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ], "pmid": "" }, { "name": "rDNA binding", "id": "GO:0000182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZID8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ], "pmid": "" }, { "name": "broad specificity oxidative DNA demethylase activity", "id": "GO:0035516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZID8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "30299", "name": "", "equation": "a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F6RK82-1", "A0A8V0ZBI2-1", "A0A8V0ZID8-1" ], "evidence": [ { "id": "30299", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/30299" } ] }, { "id": "70435", "name": "", "equation": "an N(3)-methyl-2'-deoxycytidine in single-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxycytidine in single-stranded DNA + formaldehyde + succinate + CO2 + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBI2-1", "A0A8V0ZID8-1" ], "evidence": [ { "id": "70435", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70435" } ] }, { "id": "70439", "name": "", "equation": "an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxycytidine in double-stranded DNA + formaldehyde + succinate + CO2 + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZID8-1" ], "evidence": [ { "id": "70439", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70439" } ] }, { "id": "70443", "name": "", "equation": "an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxyadenosine in double-stranded DNA + formaldehyde + succinate + CO2 + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZID8-1" ], "evidence": [ { "id": "70443", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70443" } ] }, { "id": "70447", "name": "", "equation": "an N(1)-methyl-2'-deoxyadenosine in single-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxyadenosine in single-stranded DNA + formaldehyde + succinate + CO2 + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBI2-1", "A0A8V0ZID8-1" ], "evidence": [ { "id": "70447", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70447" } ] }, { "id": "70459", "name": "", "equation": "a 1,N(6)-etheno-2'-deoxyadenosine in single-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxyadenosine in single-stranded DNA + glyoxal + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZID8-1" ], "evidence": [ { "id": "70459", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70459" } ] }, { "id": "70463", "name": "", "equation": "a 1,N(6)-etheno-2'-deoxyadenosine in double-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxyadenosine in double-stranded DNA + glyoxal + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZID8-1" ], "evidence": [ { "id": "70463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70463" } ] }, { "id": "70467", "name": "", "equation": "a 3,N(4)-etheno-2'-deoxycytidine in double-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxycytidine in double-stranded DNA + glyoxal + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZID8-1" ], "evidence": [ { "id": "70467", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70467" } ] }, { "id": "70471", "name": "", "equation": "a 3,N(4)-etheno-2'-deoxycytidine in single-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxycytidine in single-stranded DNA + glyoxal + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZBI2-1", "A0A8V0ZID8-1" ], "evidence": [ { "id": "70471", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70471" } ] }, { "id": "70487", "name": "", "equation": "a 1,N(2)-etheno-2'-deoxyguanosine in double-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxyguanosine in double-stranded DNA + glyoxal + succinate + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZID8-1" ], "evidence": [ { "id": "70487", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70487" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZBI2", "gene_name": "ALKBH3", "activity": [ { "ec_number": "1.14.11.33", "activity": "a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ] }, { "ec_number": "1.14.11.54", "activity": "an N(1)-methyladenosine in mRNA + 2-oxoglutarate + O2 = an adenosine in mRNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ] }, { "ec_number": "1.14.11.33", "activity": "", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ] }, { "ec_number": "1.14.11.54", "activity": "", "evidence": [ { "id": "A0A8V0ZBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI2" } ] } ] }, { "uniprot_ac": "A0A8V0ZID8", "gene_name": "ALKBH2", "activity": [ { "ec_number": "1.14.11.33", "activity": "a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "A0A8V0ZID8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ] }, { "ec_number": "1.14.11.33", "activity": "", "evidence": [ { "id": "A0A8V0ZID8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" } ] } ] }, { "uniprot_ac": "F6RK82", "gene_name": "ALKBH1", "activity": [ { "ec_number": "1.14.11.51", "activity": "an N(6)-methyl-2'-deoxyadenosine in DNA + 2-oxoglutarate + O2 = a 2'-deoxyadenosine in DNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] }, { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] }, { "ec_number": "1.14.11.33", "activity": "a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] }, { "ec_number": "1.14.11.33", "activity": "", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] }, { "ec_number": "1.14.11.51", "activity": "", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "F6RK82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F6RK82" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZID8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZID8" }, { "id": "PS51471", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51471" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fe2OG dioxygenase", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 236, "start_aa": "Thr", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.33", "ec_name": "a methylated nucleobase within DNA + 2-oxoglutarate + O2 = a nucleobase within DNA + formaldehyde + succinate + CO2.", "evidence": [ { "id": 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "QAAQNMLTRCQSMGYREHGILCVALHPGWVQTDMGNVAGCTPPLTVDASVGGMLKVLSNLSEKDSGAFLDWEGNVVAW", "length": 78, "header": "tr|A0A8V0ZIE9-1|A0A8V0ZIE9_CHICK Isoform 1 of C-factor OS=Gallus gallus OX=9031 GN=LOC112533303 PE=4 SV=1 CANONICAL=A0A8V0ZIE9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE9/entry#A0A8V0ZIE9-1", "sequence": { "sequence": "QAAQNMLTRCQSMGYREHGILCVALHPGWVQTDMGNVAGCTPPLTVDASVGGMLKVLSNLSEKDSGAFLDWEGNVVAW", "length": 78, "header": "tr|A0A8V0ZIE9-1|A0A8V0ZIE9_CHICK Isoform 1 of C-factor OS=Gallus gallus OX=9031 GN=LOC112533303 PE=4 SV=1 CANONICAL=A0A8V0ZIE9-1" }, "locus": { "chromosome": "11", "start_pos": 1092449, "end_pos": 1091895, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054780.1", "url": "https://www.ensembl.org/id/ENSGALT00010054780.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033108.1", "url": "https://www.ensembl.org/id/ENSGALP00010033108.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIF0-1", "uniprot_ac": "A0A8V0ZIF0", "uniprot_id": "A0A8V0ZIF0_CHICK", "mass": { "chemical_mass": 83995.0, "monoisotopic_mass": 83995.0 }, "refseq": { "ac": "XP_015155125", "name": "alpha-N-acetylglucosaminidase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155125" }, "gene_names": [ { "name": "NAGLU", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ] }, { "name": "NAGLU", "type": "synonym", "evidence": [ { "id": "XP_015155125", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155125" } ] } ], "protein_names": [ { "name": "Alpha-N-acetylglucosaminidase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.50", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0/entry#names_and_taxonomy" } ] }, { "name": "alpha-N-acetylglucosaminidase", "type": "synonym", "evidence": [ { "id": "XP_015155125", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155125" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015155125.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155125", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155125" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAGLU", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0", "locus": { "chromosome": "27", "start_pos": 4960253, "end_pos": 4956689, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021204", "url": "https://www.ensembl.org/id/ENSGALG00010021204" } ] } } ], "crossref": [ { "id": "A0A8V0ZIF0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "107055308", "url": "https://www.ncbi.nlm.nih.gov/gene/107055308", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107055308", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055308", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YGQPFVW", "url": "https://omabrowser.org/oma/group/YGQPFVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIF0", "url": "https://www.orthodb.org/?gene=A0A8V0ZIF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12872:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12872:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12971", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12971", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12972", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12972", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2024096", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024096", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155125", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155125", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVPLRMAAVAAVLAAARAPLPPELRGPAGDARQEAAVRALARRLLGSRAAAVALSVDAALAAGGPDVYRLRSPPGSTVAVAVTGSSGVAAAAGLYRYLRDFCGCHLSWSAAQLRLPDPLPRLQTEIRAATPNRYRYYQNVCAQSYSYVWWGWERWEREIDWMALSGINAAPAFAGQEALWQRVYRALGLNQTEIDAHFTGPAFLAWNRMGNLHSWAGPLPRAWHLQQLYLQYRIVERMRSLGMITVLPAFAGHVPPGVLRVFPRINATRLGNWSHFDCTLSCAYLLSPEEPMFQVIGMLFLKELIKEFGTDHIYSADTFNEMSPLSSDPAYLAGISNAVFRAMTGADPEAQWLMQGWLFQHQPDFWQPPQVQAVLRAVPLGRMIVLDLFAESKPVYEWTESFYGQPFIWCMLHNFGGNHGLFGAVEAINRGPFVARRFPNSTMVGTGLVPEGIEQNDMVYELMNELGWRHEPLDLPVWVSRYAQRRYGAPDAAAGAAWQLLLRSVYNCSGACVNHNRSPLVRRPSLHMDTQLWYNASDVYEAWRLLLSAGAALGSSPAFRYDLADVTRQAVQQLVADYYQRIRDSFQRRALPELLAAGGVLLYDLLPELDALLGSQRLFLLGRLLQSARAAATSEREAEQYERNARNQVTLWGPSGNILDYANKQLAGLVLDYYGVRWSLFVSLLVESLNTGSPFHQEQFNQAVFQVERGFVYNEKRYPATPVGDTLEITRKIFLKYYPSATQRGRDGPP", "length": 751, "header": "tr|A0A8V0ZIF0-1|A0A8V0ZIF0_CHICK Isoform 1 of Alpha-N-acetylglucosaminidase OS=Gallus gallus OX=9031 GN=NAGLU PE=3 SV=1 CANONICAL=A0A8V0ZIF0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0/entry#A0A8V0ZIF0-1", "sequence": { "sequence": "MAVPLRMAAVAAVLAAARAPLPPELRGPAGDARQEAAVRALARRLLGSRAAAVALSVDAALAAGGPDVYRLRSPPGSTVAVAVTGSSGVAAAAGLYRYLRDFCGCHLSWSAAQLRLPDPLPRLQTEIRAATPNRYRYYQNVCAQSYSYVWWGWERWEREIDWMALSGINAAPAFAGQEALWQRVYRALGLNQTEIDAHFTGPAFLAWNRMGNLHSWAGPLPRAWHLQQLYLQYRIVERMRSLGMITVLPAFAGHVPPGVLRVFPRINATRLGNWSHFDCTLSCAYLLSPEEPMFQVIGMLFLKELIKEFGTDHIYSADTFNEMSPLSSDPAYLAGISNAVFRAMTGADPEAQWLMQGWLFQHQPDFWQPPQVQAVLRAVPLGRMIVLDLFAESKPVYEWTESFYGQPFIWCMLHNFGGNHGLFGAVEAINRGPFVARRFPNSTMVGTGLVPEGIEQNDMVYELMNELGWRHEPLDLPVWVSRYAQRRYGAPDAAAGAAWQLLLRSVYNCSGACVNHNRSPLVRRPSLHMDTQLWYNASDVYEAWRLLLSAGAALGSSPAFRYDLADVTRQAVQQLVADYYQRIRDSFQRRALPELLAAGGVLLYDLLPELDALLGSQRLFLLGRLLQSARAAATSEREAEQYERNARNQVTLWGPSGNILDYANKQLAGLVLDYYGVRWSLFVSLLVESLNTGSPFHQEQFNQAVFQVERGFVYNEKRYPATPVGDTLEITRKIFLKYYPSATQRGRDGPP", "length": 751, "header": "tr|A0A8V0ZIF0-1|A0A8V0ZIF0_CHICK Isoform 1 of Alpha-N-acetylglucosaminidase OS=Gallus gallus OX=9031 GN=NAGLU PE=3 SV=1 CANONICAL=A0A8V0ZIF0-1" }, "locus": { "chromosome": "27", "start_pos": 4959759, "end_pos": 4956888, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051379.1", "url": "https://www.ensembl.org/id/ENSGALT00010051379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030570.1", "url": "https://www.ensembl.org/id/ENSGALP00010030570.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:107055308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107055308", "resource": "KEGG Pathway" }, { "id": "R-GGA-2024096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2024096", "resource": "Reactome", "description": "HS-GAG degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QHV1-1", "protein_name": "Alpha-N-acetylglucosaminidase", "gene_name": "NAGLU", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAVVVAAALGLLLLAAAGSSAGDEAREAAAVRELLARLLGPGPAASFSVSVERALAAESGLDTYRLSGGGPGAQVRVIGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPQPLPAVPEELTEATPNRYRYYQNVCTQSYSFVWWDWARWEQEIDWMALNGINLALAWSGQEAIWQRVYLALGLTQTEIDEFFTGPAFLAWGRMGNLHTWSGPLPRSWHLKQLYLQHRILDRMRSFGMIPVLPAFAGHVPKALTRVFPQISVTQMGSWGHFNCSYSCSFLLAPEDPLFPIVGSLFLRELTKEFGTDHIYGADTFNEMQPPSSEPSYLAAATAAVYQAMITVDPDAVWLLQGWLFQHQPQFWGPAQVGAVLGAVPRGRLLVLDLFAESQPVYVRTASFLGQPFIWCMLHNFGGNHGLFGALESVNQGPAAARLFPNSTMAGTGMAPEGIGQNEVVYALMAELGWRKDPVADLGTWVTSFAARRYGVSQGDAEAAWRLLLRSVYNCSGEGCTGHNRSPLVRRPSLQMATTVWYNQSDVFEAWRLLLKATPTLASSPAFRYDLVDITRQAVQELVSLYYEEARTAYLNKELVSLMRAGGILAYELLPALDKVLASDSHFLLGSWLEQARGVAVSEAEALFYEQNSRYQLTLWGPEGNILDYANKQLAGLVADYYTPRWRLFMEMLVESLVQGIPFQQHQFDQNVFQLEQTFVLGTRRYPSQPQGDTVDLAKKLFLKYYPRWVAGSL", "length": 744 }, "evidence": [ { "id": "A0A8V0ZIF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZIF0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZZL3-1", "protein_name": "Alpha-N-acetylglucosaminidase", "gene_name": "Naglu", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAAGLAAILGFLLLARDLVGDEAQEAEAVRELVVRLLGPGPAADFLVSVERALANESGLDTYSLSGGGGVPVLVRGSSGVAAAAGLHRYLRDFCGCHIAWSSSQLHLPSPLPAVPDGLTEATPNRYRYYQNVCTHSYSFVWWDWARWEQEIDWMALNGINLALAWNGQEAIWQRVYLALGLTQSEIDNYFTGPAFLAWGRMGNLHTWDGPLPRSWHLKQLYLQHRILDRMRSFGMTPVLPAFAGHVPKAITRVFPQVNVIQLGNWGHFNCSYSCSFLLAPGDPLFPLIGTLFLRELTKEFGTDHIYGADTFNEMQPPFSDPSYLAAATAAVYEAMVTVDPDAVWLLQGWLFQHQPQFWGPSQIKAVLEAVPRGRLLVLDLFAETQPVYSRTASFHGQPFIWCMLHNFGGNHGLFGALEDVNQGPQAARLFPNSTMVGTGIAPEGIGQNEVVYALMAELGWRKDPVPDLVAWVSSFASRRYGVSQPDAVAAWRLLLRSVYNCSGEACSGHNRSPLVKRPSLQMSTAVWYNRSDVFEAWRLLLRAAPNLTASPAFRYDLLDVTRQAVQELVSSCYEEARTAFLNQDLDLLLRAGGLLTYKLLPSLDELLASNSHFLLGTWLDQAREVAVSESEAQFYEQNSRYQITLWGPEGNILDYANKQLAGLVADYYQPRWCLFLGTLAHSLARGIPFQQHQFEKSVFPLEQAFINNKKRYPIQPQGDTVDLSKKIFLKFHPQPDSL", "length": 739 }, "evidence": [ { "id": "A0A8V0ZIF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZIF0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HLX3-1", "protein_name": "Alpha-N-acetylglucosaminidase", "gene_name": "Naglu", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEAAVLAVALGFLLLARGSVGDEARETEAVRQLVVRLLGPEPAADFLVSVERELATEAGLDTYKLSGGGSGIPVRVRGSTGVAAAAGLYRYLRDFCGCQVAWSGSQLRLPRPLPALLQELTEATPNRYRYYQNVCTHSYSFVWWDWARWEQEIDWMALNGINLALAWSGQEAIWQRVYLILGLTQSEIDKHFTGPAFLAWERMGNLHTWGGPLPRSWHLKQLYLQHRILDRMRAFGMIPVLPAFAGHVPKAITRVFPQVNVFQLGSWGHFNCSYSCSFLLAPGDPVFPLIGSLFLRELIKEFGTDHIYGADTFNEMQPISSDPSFLTAATAAVYEAMISVDPDAIWLLQGWLFQHQPQFWGPAQVKAVLQAVPRGRLLVLDLFAESHPVYMQTASFYGQPFIWCMLHNFGGNHGLFGALEAVNQGPRAARIFPNSTMVGTGIAPEGIGQNEMVYALMAELGWRKDPVPDLEVWVSRFASHRYGMSHPDAEAAWRLLLRSVYNCPGETYNGHNRSPLVKRPSLQINTIVWYNRSDVFEAWRLLLTAAPNLTTSKAFRYDLLDVTRQSLQELVSLFYEEARIAFMKEELDLLLRAGGIITRKLLPALDELLASDSRFLLGTWLNQARAMAVSEDEAQFYELNSLYQLTLWGPEGNIMDYANKQLAGLVADYYQPRWGLFMEALAHSLARGVPFRQHEFEKNVFPLELAFIINKKRYPSHPQGDTVDLSKKLFLKYHPQAGSL", "length": 740 }, "evidence": [ { "id": "A0A8V0ZIF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZIF0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O88325-1", "protein_name": "Alpha-N-acetylglucosaminidase", "gene_name": "Naglu", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAAGLAVILGFLLLAGGSVGDEAREAKAVRELVVRLLGPGPAANFLVSVERALADESGLDTYSLSGGGGVPVLVRGSTGVAAAAGLHRYLRDFCGCQVAWSSAQLHLPWPLPAVPDGLTETTPNRYRYYQNVCTHSYSFVWWDWARWEQEIDWMALNGINLALAWNGQEAIWQRVYLALGLTQSEIDTYFTGPAFLAWGRMGNLHTWDGPLPRSWHLSQVYLQHRILDRMRSFGMIPVLPAFAGHVPKAITRVFPQVNVIKLGSWGHFNCSYSCSFLLAPGDPMFPLIGNLFLRELTKEFGTDHIYGADTFNEMQPPFSDPSYLAATTAAVYEAMVTVDPDAVWLLQGWLFQHQPQFWGPSQIRAVLEAVPRGRLLVLDLFAESHPVYMHTASFHGQPFIWCMLHNFGGNHGLFGALEDVNRGPQAARLFPNSTMVGTGIAPEGIGQNEVVYALMAELGWRKDPVPDLMAWVSSFAIRRYGVSQPDAVAAWKLLLRSVYNCSGEACSGHNRSPLVKRPSLQMSTAVWYNRSDVFEAWRLLLTAAPNLTTSPAFRYDLLDVTRQAVQELVSLCYEEARTAYLKQELDLLLRAGGLLVYKLLPTLDELLASSSHFLLGTWLDQARKAAVSEAEAQFYEQNSRYQITLWGPEGNILDYANKQLAGLVADYYQPRWCLFLGTLAHSLARGVPFQQHEFEKNVFPLEQAFVYNKKRYPSQPRGDTVDLSKKIFLKYHPQPDSL", "length": 739 }, "evidence": [ { "id": "A0A8V0ZIF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZIF0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P54802-1", "protein_name": "Alpha-N-acetylglucosaminidase", "gene_name": "NAGLU", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAVAVAAAVGVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKPGLDTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPRPLPAVPGELTEATPNRYRYYQNVCTQSYSFVWWDWARWEREIDWMALNGINLALAWSGQEAIWQRVYLALGLTQAEINEFFTGPAFLAWGRMGNLHTWDGPLPPSWHIKQLYLQHRVLDQMRSFGMTPVLPAFAGHVPEAVTRVFPQVNVTKMGSWGHFNCSYSCSFLLAPEDPIFPIIGSLFLRELIKEFGTDHIYGADTFNEMQPPSSEPSYLAAATTAVYEAMTAVDTEAVWLLQGWLFQHQPQFWGPAQIRAVLGAVPRGRLLVLDLFAESQPVYTRTASFQGQPFIWCMLHNFGGNHGLFGALEAVNGGPEAARLFPNSTMVGTGMAPEGISQNEVVYSLMAELGWRKDPVPDLAAWVTSFAARRYGVSHPDAGAAWRLLLRSVYNCSGEACRGHNRSPLVRRPSLQMNTSIWYNRSDVFEAWRLLLTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKELASLLRAGGVLAYELLPALDEVLASDSRFLLGSWLEQARAAAVSEAEADFYEQNSRYQLTLWGPEGNILDYANKQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQQHQFDKNVFQLEQAFVLSKQRYPSQPRGDTVDLAKKIFLKYYPRWVAGSW", "length": 743 }, "evidence": [ { "id": "A0A8V0ZIF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZIF0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54DW5-1", "protein_name": "Alpha-N-acetylglucosaminidase", "gene_name": "naglu", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLKINKSKFGFLIFLTFLVINFSKSIQFNNQINFNDNGNEILNNIEDQRFNNVLLDLHMERDYKDGNKQISTVYGLIERLFNFEMTLFFKLKIEESEWMTGEYYEISTESVENEDSSKNITFVTIRADSGVNLAMGLQYYLKYYCFCSYTWSGDQCSITSYSQLPAVTEGSVSIPVISAYRYYMNVCTFGYSTTWWNWSRWEREIDWMALNGYNLPLAFVGQEYIWYRVFSELGLSFDQISTWLTGPAFLPWNRMGNVNGWGGPITLDWLEKQRDLQIKILERMRQYGMKPVLPGFAGHIPGAIQQLFPQANISVLSTWCNFNGTFYLESTDPLFAKITTMFIGELIDVFGTDHFYNFDPFNELEPPSNDTDYLRQTSQSMYENVLLADPKAVWVLQGWFIVDAPEFWQAKQTEAWFSGVPIGGVLVLDLWSDVIPGWTTTNYYYGHYWVWCMLHNFGGRSGMYGRLPWISSNPITARGLSPNMVGIGLTPEAIEQNVVVYDMMSEMSWRSVQPNLTEWVTQYTHRRYGKLVPEIVDVWISLVNTVFNATAATARANMGAPESFIALRPQLTFGNNSFYNPNILYNAWNVFSMVDDEYVISTETFEFDISEFTMQSLSNYFMDQYFLLIEAFNASDVQTLSTISIELLDIINYMDEIASTQSSLQLGLWTYRARLWAYPTNDIPTLQNSSNSNTAPYEFNARNVLTLWGPSNSVLHDYAFKLWSGLVSDFYSPRWQLFLKSLVQSVENRKPFNKESFNRMVENLEEQWVVQQTIYPTVPVGQAYNTSKYIQTHLKINF", "length": 798 }, "evidence": [ { "id": "A0A8V0ZIF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZIF0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9FNA3-1", "protein_name": "Alpha-N-acetylglucosaminidase", "gene_name": "NAGLU", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MHSIKLVLLVLLIISFHSQTVSKHHPTIDGLLDRLDSLLPTSSVQESAAKGLLQRLLPTHSQSFELRIISKDACGGTSCFVIENYDGPGRIGPEILIKGTTGVEIASGLHWYLKYKCNAHVSWDKTGGIQVASVPQPGHLPRIDSKRIFIRRPVPWNYYQNVVTSSYSYVWWGWERWEREIDWMALQGINLPLAFTGQEAIWQKVFKRFNISKEDLDDYFGGPAFLAWARMGNLHAWGGPLSKNWLDDQLLLQKQILSRMLKFGMTPVLPSFSGNVPSALRKIYPEANITRLDNWNTVDGDSRWCCTYLLNPSDPLFIEIGEAFIKQQTEEYGEITNIYNCDTFNENTPPTSEPEYISSLGAAVYKAMSKGNKNAVWLMQGWLFSSDSKFWKPPQLKALLHSVPFGKMIVLDLYAEVKPIWNKSAQFYGTPYIWCMLHNFGGNIEMYGALDSISSGPVDARVSKNSTMVGVGMCMEGIEQNPVVYELTSEMAFRDEKVDVQKWLKSYARRRYMKENHQIEAAWEILYHTVYNCTDGIADHNTDFIVKLPDWDPSSSVQDDLKQKDSYMISTGPYETKRRVLFQDKTADLPKAHLWYSTKEVIQALKLFLEAGDDLSRSLTYRYDMVDLTRQVLSKLANQVYTEAVTAFVKKDIGSLGQLSEKFLELIKDMDVLLASDDNCLLGTWLESAKKLAKNGDERKQYEWNARTQVTMWYDSNDVNQSKLHDYANKFWSGLLEDYYLPRARLYFNEMLKSLRDKKIFKVEKWRREWIMMSHKWQQSSSEVYPVKAKGDALAISRHLLSKYFP", "length": 806 }, "evidence": [ { "id": "A0A8V0ZIF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZIF0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VLL5-1", "protein_name": "Alpha-N-acetylglucosaminidase", "gene_name": "Naglu", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQLNWKLALALLAVLCLQLAQGSELNWDAASGPEMGLQMAAHLAPSTPKDVQETAAMAVISRVIGERSSQLFKVQVNKNMDLRSFQISMLDDGRILLMGWDGVSVCKALHHYLKYVLNKDVDWFKMRIELPTNLQLPNVTIESKSASPIIYHQNVCTWSYSFAWWGIEQWRRHLDWMALMGISLTIAPVQEAIWVKVYTDMGLRMEEIDEHLAGPAFQAWQRMGNIRGWAGPLTPAWRRYQLLLQQEIITAQRNLGMSVALPAFAGHVPRALKRLNPESTFMEVQRWNQFPDRYCCGLFVEPTENLFKEIASRFLHNIITKYGSNHIFFCDPFNELEPPVAKPEYMRSTAAAIYESMRGIDPQAIWLLQGWMFVKNPFWTTDMAEAFLTAAPRGRILVLDLQSEQFPQYELTRSYFGQPFIWCMLHNFGGTLGMFGSAKLINSGIEEARRLPNSSLVGTGITPEGIGQNYVMYSFTLERGWSNTSLDLDSWFTNFSHSRYGVKDERLEQAWLLLKNSVYSFRGLQKMRGQYVVTRRPSFNQEPFTWYNASAVLDAWHLLLTFRAIIPLEDNRYEIYEHDLVDITRQFLQISADQLYINLRSAYRKRQVSRFEFLSVKLLKLFDDMELILASSRNFLLGNWLQQAKQAAPNTGQQRNFEFNARNQITAWGPDGQILDYACKQWSGLVSDYYRPRWRLFLEDVTVALHAGRPFNGTAFKLKVSHEIELPFSNKDDVYPVTPVGNTWLISQDIFETWKGYSKDTLFLHNNRLSVPQKAGPK", "length": 778 }, "evidence": [ { "id": "A0A8V0ZIF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZIF0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan catabolic process", "id": "GO:0030200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ], "pmid": "" }, { "name": "heparin proteoglycan metabolic process", "id": "GO:0030202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ], "pmid": "" }, { "name": "lysosomal lumen", "id": "GO:0043202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alpha-N-acetylglucosaminidase activity", "id": "GO:0004561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004561", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ], "pmid": "" }, { "name": "iron ion sequestering activity", "id": "GO:0140315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140315", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-1678742", "name": "NAGLU hydrolyses Heparan sulfate chain(4)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2090069" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZIF0-1" ], "evidence": [ { "id": "R-GGA-1678742", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1678742" } ] }, { "id": "R-GGA-2090038", "name": "NAGLU hydrolyses heparan chain(2)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "lysosomal lumen", "input_participant_list": [ "R-ALL-2090053" ], "output_participant_list": [ "R-ALL-9941448" ], "enzyme_list": [ "A0A8V0ZIF0-1" ], "evidence": [ { "id": "R-GGA-2090038", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2090038" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2090053", "participant_name": "GlcNAc- group [lysosomal lumen]", "crossref": [ { "id": "747401", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-2090069", "participant_name": "GlcNAc-IdoA2S-GlcNS3S- group [lysosomal lumen]", "crossref": [ { "id": "63807", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9941448", "participant_name": "-R [lysosomal lumen]", "crossref": [ { "id": "24433", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZIF0", "gene_name": "NAGLU", "activity": [ { "ec_number": "3.2.1.50", "activity": "Hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.", "evidence": [ { "id": "A0A8V0ZIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ] }, { "ec_number": "3.2.1.50", "activity": "", "evidence": [ { "id": "A0A8V0ZIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" }, { "id": "PF12972", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12972" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-N-acetylglucosaminidase C-terminal", "eco_id": "ECO_0000259", "start_pos": 479, "end_pos": 737, "start_aa": "Trp", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" }, { "id": "PF12971", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12971" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-N-acetylglucosaminidase N-terminal", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 121, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZIF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF0" }, { "id": "PF05089", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-N-acetylglucosaminidase tim-barrel", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 470, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.2.1.50", "ec_name": "Hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.", "evidence": [ { "id": "3.2.1.50", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.2.1.50" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 267, "end_pos": 269 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 441, "end_pos": 443 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 517, "end_pos": 519 }, { "start_pos": 536, "end_pos": 538 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"MNRMEETDGTDGVDGMDRMDGADEQSPMGSFGPLCPRADAQSCFAGQCVLSPHHGKAWVYRDGIQPQVGLQPKGTTWGQSSHFGAARSPEGTTLLPPSLATTPSSHPLSPLAPQKGVRGWSPPSLSSPRPGAAPLGGGHGGLGAACPSPASPCSLPNTALMRTSWSAALTASELRAAAGGGGGGGKERGGGGSGTRAWCGQAEKHRTDRQTRGASELPACLLLVFLVAPVHLAAPRHVAVFHEPSGGSGDGEEASALPPAQPVTPGSGPTVGDTVGTAVTNSSAPGNVLDGLVAFFKEYMLLVVVVGSLAFVLLFIICAAVIVRQKHKASAYYPSSFPKKKYVDQRDKTGGPRDFSEVPEKAPDPDAEEPLDCGRQLQADILAAAQNLKSPHKAPLANGAQGEREGGEEEGSEHPVEPPPQNQDAEGVGPEATSAEGKETQDGSPST", "length": 447, "header": "tr|A0A8V0ZII7-1|A0A8V0ZII7_CHICK Isoform 1 of Transmembrane protein 119 OS=Gallus gallus OX=9031 GN=TMEM119 PE=1 SV=1 CANONICAL=A0A8V0ZII7-1" }, "locus": { "chromosome": "15", "start_pos": 6544030, "end_pos": 6541584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054839.1", "url": "https://www.ensembl.org/id/ENSGALT00010054839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033148.1", "url": "https://www.ensembl.org/id/ENSGALP00010033148.1" } ] } } ], "glycosylation": [ 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"https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZII7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZII7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of osteoblast proliferation", "id": "GO:0033690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033690", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZII7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZII7" } ], "pmid": "" }, { "name": "positive regulation of bone mineralization", "id": "GO:0030501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030501", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZII7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZII7" } ], "pmid": "" }, { "name": "positive regulation of osteoblast differentiation", "id": "GO:0045669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZII7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZII7" } ], "pmid": "" }, { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZII7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZII7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 264, 270 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 281, "end_pos": 283 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", 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"tr|A0A8V0ZIJ1-1|A0A8V0ZIJ1_CHICK Isoform 1 of ribonuclease H OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZIJ1-1" }, "locus": { "chromosome": "9", "start_pos": 120739, "end_pos": 119777, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054850.1", "url": "https://www.ensembl.org/id/ENSGALT00010054850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033153.1", "url": "https://www.ensembl.org/id/ENSGALP00010033153.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ1" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 132, "start_aa": "Met", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.26.4", "ec_name": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "3.1.26.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.26.4" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIK7-1", "uniprot_ac": "A0A8V0ZIK7", "uniprot_id": "A0A8V0ZIK7_CHICK", "mass": { "chemical_mass": 32359.0, "monoisotopic_mass": 32359.0 }, "refseq": { "ac": "XP_421619", "name": "myozenin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421619" }, "gene_names": [ { "name": "MYOZ1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ] }, { "name": "MYOZ1", "type": "synonym", "evidence": [ { "id": "XP_421619", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421619" } ] } ], "protein_names": [ { "name": "Myozenin 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7/entry#names_and_taxonomy" } ] }, { "name": "myozenin-1", "type": "synonym", "evidence": [ { "id": "XP_421619", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421619" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_421619.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421619" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYOZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7", "locus": { "chromosome": "6", "start_pos": 16807787, "end_pos": 16789337, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021224", "url": "https://www.ensembl.org/id/ENSGALG00010021224" } ] } } ], "crossref": [ { "id": "A0A8V0ZIK7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "423744", "url": "https://www.ncbi.nlm.nih.gov/gene/423744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TFQMPKI", "url": "https://omabrowser.org/oma/group/TFQMPKI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIK7", "url": "https://www.orthodb.org/?gene=A0A8V0ZIK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15941", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15941", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15941:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15941:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421619", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421619", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLAGTPAPLKRKKPTKLIGKLTHEVMPQEVTKLNLGKKISIPRDVMLEELSLLTNKGSKMFKLRQLRVEKFIYENNPDAFTDNSVDHFQKFIPPGGHYGEDAHGYGHGRMVGGVTAGHHGSSKQHYSTVPPRPGSKGGPGDSEGEHAELSAGTAGEGGHGTEKDGKSGGKKPLVKTYISPWERAMGISPEDKSQLTIDLLSYSPKADFPHYKSFNRTAMPYGGYEKAAKRMTFKVPQFDICPLLPESLVLYNQNFRNRPSFNRTPIPWMPSGESSEYHTDINVPRSGETEEL", "length": 293, "header": "tr|A0A8V0ZIK7-1|A0A8V0ZIK7_CHICK Isoform 1 of Myozenin 1 OS=Gallus gallus OX=9031 GN=MYOZ1 PE=3 SV=1 CANONICAL=A0A8V0ZIK7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7/entry#A0A8V0ZIK7-1", "sequence": { "sequence": "MPLAGTPAPLKRKKPTKLIGKLTHEVMPQEVTKLNLGKKISIPRDVMLEELSLLTNKGSKMFKLRQLRVEKFIYENNPDAFTDNSVDHFQKFIPPGGHYGEDAHGYGHGRMVGGVTAGHHGSSKQHYSTVPPRPGSKGGPGDSEGEHAELSAGTAGEGGHGTEKDGKSGGKKPLVKTYISPWERAMGISPEDKSQLTIDLLSYSPKADFPHYKSFNRTAMPYGGYEKAAKRMTFKVPQFDICPLLPESLVLYNQNFRNRPSFNRTPIPWMPSGESSEYHTDINVPRSGETEEL", "length": 293, "header": "tr|A0A8V0ZIK7-1|A0A8V0ZIK7_CHICK Isoform 1 of Myozenin 1 OS=Gallus gallus OX=9031 GN=MYOZ1 PE=3 SV=1 CANONICAL=A0A8V0ZIK7-1" }, "locus": { "chromosome": "6", "start_pos": 16804041, "end_pos": 16791615, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051434.1", "url": "https://www.ensembl.org/id/ENSGALT00010051434.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030625.1", "url": "https://www.ensembl.org/id/ENSGALP00010030625.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 6, "start_aa": "Thr", "end_pos": 6, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr6", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MLL1-1", "protein_name": "Myozenin-1", "gene_name": "Myoz1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPLSGTPAPNKRRKPSKLIMELTGGGRENSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLETAGQGFSYGKGSSGGQAGGSGSAGQYGSDQHHQQGSGFGAGGAGGPGGQAGRRGASGTAGTGEPGTGDQAGGEGKHVTVFKTYISPWDRAMGVDPQQKVELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYTVDIGIPLDGETEEL", "length": 297 }, "evidence": [ { "id": "A0A8V0ZIK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIK7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A7U8-1", "protein_name": "Myozenin 1", "gene_name": "Myoz1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESEHSRSVKSPSTMPLSGTPAPNKRRKSSKLIMELTGGGRESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLESAGQGFSYGKGSSGGQAGASGSAGQYGSDRHQQGSGFGAGGAGGPGGQAGGGAAPGTVGVGEPGSGDQAGGDGKHVTVFKTYISPWDRAMGVDPQQKVELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEHVDYSVDIGIPLDGETEEL", "length": 310 }, "evidence": [ { "id": "A0A8V0ZIK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIK7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JK37-1", "protein_name": "Myozenin-1", "gene_name": "Myoz1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLSGTPAPNKRRKSSKLIMELTGGGRESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLETAGQGFSYGKGSSGGQAGSSGSAGQYGSDRHQQGSGFGAGGSGGPGGQAGGGGAPGTVGLGEPGSGDQAGGDGKHVTVFKTYISPWDRAMGVDPQQKVELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEHVDYNVDVGIPLDGETEEL", "length": 296 }, "evidence": [ { "id": "A0A8V0ZIK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIK7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP98-1", "protein_name": "Myozenin-1", "gene_name": "MYOZ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGGSGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITVFKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL", "length": 299 }, "evidence": [ { "id": "A0A8V0ZIK7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIK7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein serine/threonine phosphatase inhibitor activity", "id": "GO:0004865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" }, { "name": "FATZ binding", "id": "GO:0051373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051373", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" }, { "name": "telethonin binding", "id": "GO:0031433", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031433", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" }, { "name": "actinin binding", "id": "GO:0042805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" }, { "name": "negative regulation of calcineurin-NFAT signaling cascade", "id": "GO:0070885", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070885", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" }, { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" }, { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" }, { "name": "skeletal muscle tissue development", "id": "GO:0007519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007519", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" }, { "name": "negative regulation of skeletal muscle tissue regeneration", "id": "GO:0043417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 6 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 }, { "start_pos": 263, "end_pos": 265 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIL2-1", "uniprot_ac": "A0A8V0ZIL2", "uniprot_id": "A0A8V0ZIL2_CHICK", "mass": { "chemical_mass": 57084.0, "monoisotopic_mass": 57084.0 }, "refseq": { "ac": "XP_015150651", "name": "tripartite motif-containing protein 45 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150651" }, "gene_names": [ { "name": "TRIM45", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2" } ] }, { "name": "TRIM45", "type": "synonym", "evidence": [ { "id": "XP_015150651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150651" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2/entry#names_and_taxonomy" } ] }, { "name": "tripartite motif-containing protein 45 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015150651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150651" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015150651.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015150651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150651" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRIM45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2", "locus": { "chromosome": "1", "start_pos": 79419598, "end_pos": 79411881, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022550", "url": "https://www.ensembl.org/id/ENSGALG00010022550" } ] } } ], "crossref": [ { "id": "A0A8V0ZIL2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIL2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19785", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19785", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769776", "url": "https://www.ncbi.nlm.nih.gov/gene/769776", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769776", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769776", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TRCPLCM", "url": "https://omabrowser.org/oma/group/TRCPLCM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIL2", "url": "https://www.orthodb.org/?gene=A0A8V0ZIL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25462", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25462", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25462:SF291", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25462:SF291", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00630", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00630", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015150651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015150651", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAASRCPVCAEPCVEARLLPCLHSLCAPCLRRLGTLGEPGRAAAAFSVLCPLCDAEVALPPGGLGQLVPDYTALGRGGAAGTAGCDLCADGAAARRCQTCGAHLCLFCCQAHRRQKKTASHVVMELESTKDCSQAGKPFFCPSHPSEELGLFCEQCDQPVCQDCVAERHRQHPYDFTSNAVHRHGDSLRELLRSTQQRMSALEDVLGQTDGVGSAIRARAEAVATEICLFARGYVKAIEEHRDRLLKQLEDLKVQKENLLHLQKAQLQQLLLDMRTGVEFTERLLTSGSDLGILVTKGVVASRLAKLNSAAYSTHPSVDDSIQFSPQERAGQCHGYEVFGAVICKAVDPAKCTLQGEGLRSARQNELTGFTLLCSDTTGERMGRGGEAVVVTITHKDKKDCAVKPTVCDNGDGTYHISYSPEEPGLYAVCVYVKGQHVQGSPFIVMVKSQFRKHQGMFHCCTFCSSGGQKAARCACGGTMPGGYQGCGHGHKGHPGCPHWSCCGQVKMSSECLSGLPSDRSQRSLLRTVEL", "length": 531, "header": "tr|A0A8V0ZIL2-1|A0A8V0ZIL2_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM45 PE=3 SV=1 CANONICAL=A0A8V0ZIL2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2/entry#A0A8V0ZIL2-1", "sequence": { "sequence": "MAASRCPVCAEPCVEARLLPCLHSLCAPCLRRLGTLGEPGRAAAAFSVLCPLCDAEVALPPGGLGQLVPDYTALGRGGAAGTAGCDLCADGAAARRCQTCGAHLCLFCCQAHRRQKKTASHVVMELESTKDCSQAGKPFFCPSHPSEELGLFCEQCDQPVCQDCVAERHRQHPYDFTSNAVHRHGDSLRELLRSTQQRMSALEDVLGQTDGVGSAIRARAEAVATEICLFARGYVKAIEEHRDRLLKQLEDLKVQKENLLHLQKAQLQQLLLDMRTGVEFTERLLTSGSDLGILVTKGVVASRLAKLNSAAYSTHPSVDDSIQFSPQERAGQCHGYEVFGAVICKAVDPAKCTLQGEGLRSARQNELTGFTLLCSDTTGERMGRGGEAVVVTITHKDKKDCAVKPTVCDNGDGTYHISYSPEEPGLYAVCVYVKGQHVQGSPFIVMVKSQFRKHQGMFHCCTFCSSGGQKAARCACGGTMPGGYQGCGHGHKGHPGCPHWSCCGQVKMSSECLSGLPSDRSQRSLLRTVEL", "length": 531, "header": "tr|A0A8V0ZIL2-1|A0A8V0ZIL2_CHICK Isoform 1 of RING-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=TRIM45 PE=3 SV=1 CANONICAL=A0A8V0ZIL2-1" }, "locus": { "chromosome": "1", "start_pos": 79419427, "end_pos": 79411937, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054880.1", "url": "https://www.ensembl.org/id/ENSGALT00010054880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033178.1", "url": "https://www.ensembl.org/id/ENSGALP00010033178.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:769776", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769776", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A7S9-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Trim45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSENRKPLPGFVNKLQDASASGSSGKTHCPSCLRLFKVPRLLPCLHTVCTSCLERLDPFSVVDIRGGDSDTSSEGSIFQEPKSCSLKPQIGILCPVCDAQVDLPLGGVKALTVDHLAMNDVMLESLHGEGQGLVCDLCSDREVEKRCQTCKANLCHFCCQAHRRQKKTTDHTMVDLKDLKGYSRVGKPILCPSHPAEELRLFCELCDRPVCRDCVVGEHREHPYDFTSNVIHKHGDSVRELLRDTQPHVEALEDALAQIKSSNNALQERVEAVAADVRTFSEGYIRAIEEHRDKLLRQLDDIRVQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILVTKGVVVERLRKLNKVEYSARPGVNHKICFSPQEKARCQGYEVYGAINTQEVDPAQCVLQGEDLHRAREKQTASFTLVCKDATGESMSRGGDNVRVEVVPKNKKDSPIRTVVQDNKDGSYRVSYTPKEPGVYTVWVGIREQQVQGSPFNVTVRRKHRPHPGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGRPHWSCCGKFIEKSECSYSTGQSAPRSLLRTVAL", "length": 579 }, "evidence": [ { "id": "A0A8V0ZIL2", "url": "https://omabrowser.org/oma/group/A0A8V0ZIL2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H907-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Trim45", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSENRKPLLGFVHKVPDANASGSSGKTHCPSCLGLFKAPRLLPCLHTVCTTCLEKLEPFSVVDIRGGDSDTSSERSIFQEPKSRSLQPQIGILCPVCDAQVDLPLGGVKALTIDHLAMNDVMLQSLRGEGQGLVCDLCSDREVEKRCQTCKANLCHFCCQAHRRQKKTMYHSMVDLKDLKGYSRVGKPILCPTHPAEELRLFCELCDQPVCRDCVVGEHREHPYDFTSNVIHKHGDSVRELLRGTQPHVEALEEALAQIKTMNSGLQERVEAVAADVRTFSEGYIKAIEEHRDKLLQQLDTIRVQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKGVVVERLQKLNKVEYSSRPGVNDKICFSPREKAGQCRGYEVYGTINTKEVDPAKCVLQGEDLQRAREKQTTSFTLLCKDASGESLGRGGEDVQVAVVPKDKKDSPIRTVVQDNKDGSYHVSFTPKEAGVYIVWVCIREQHVQGSPFTVTVRRKHRSHPGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGRPHWSCCGKFIEKSDCTYTGGQSAPRSLLRTVAL", "length": 580 }, "evidence": [ { "id": "A0A8V0ZIL2", "url": "https://omabrowser.org/oma/group/A0A8V0ZIL2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5BIM1-1", "protein_name": "E3 ubiquitin-protein ligase TRIM45", "gene_name": "TRIM45", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEKRRPLLGFVGKLPSGTTAGNSGKTHCPLCMGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGESDTSSEGSVFQELKPRALQPQIGILCPVCDAQVDLPMGGVKALTIDHLAMNDVMLESLRGEGQGLVCDLCSDREVEKRCQTCKANLCRFCCQAHRRQKKTTYHTMVDLKDLKGYSQIGKPILCPAHPAEELRLFCELCDRPVCRDCVVGEHREHPCDFTSNVIHKHGDSVRELLRGTQPHVEALEEALAQIKGTNSAVQERVKAVAADIRTFSEGYIKAIEEHRDKLLKQLEDIRVQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKGVVVERLTKLNKVEYSAHPGVNEKISFSPKQKAGLCRGYEVYGAINTKEVDPAKCVLQGEDLHRAREKQPASFIVLCKDATGESMGRGGDNVQVTVIPNDKKDSPVKTMVHDNKDGTYYVSYTPKEPGTYTVLVCVKEQHVQGSPFTVTVRKRHRSHPGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGRPHWSCCGKFAEKSECTWAGGQSAPRSLLRTVAL", "length": 580 }, "evidence": [ { "id": "A0A8V0ZIL2", "url": "https://omabrowser.org/oma/group/A0A8V0ZIL2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PFY8-1", "protein_name": "E3 ubiquitin-protein ligase TRIM45", "gene_name": "Trim45", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEIRKPLLGFVHKLQDANASGSSGKTHCPTCLRLFKVPRLLPCLHTVCTTCLEKLDPFSVVDIRGGDSDTSSEGSVFQDPELCSLQPQIGILCPVCDAQVDLPLGGVKALTVDHLAMNDVLLENLRGEGQGLVCDLCSDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSQVGKPILCPSHPAEELRLFCELCDRPVCRDCVVGEHREHPYDFTSNVIHKHGDSVRELLRDTQPHVEALEDALAQIKSVNNALQERVEAVAADVRTFSEGYIKAIEEHRDKLLQQLDDIRIQRETALQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKGVVVERLRKLNKVEYSARPGVNHKICFSPQEKAGQCQGYEVYGAINTQEVDPAQCVLQGEDLHRAREKQTASFTLFCKDASGQSMGRGGDNVHVEVVPKDKKDSPIRTVVQDNKDGSYRVSYTPKEPGIYTVWVCIREQHVQGSPFNVTVRRKHRPHPGVFHCCTFCSSGGQKAARCACGGTMPGGYLGCGHGHKGHPGRPHWSCCGKFIEKSECSFTSGQGAPRSLLRTVAL", "length": 580 }, "evidence": [ { "id": "A0A8V0ZIL2", "url": "https://omabrowser.org/oma/group/A0A8V0ZIL2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8W5-1", "protein_name": "E3 ubiquitin-protein ligase TRIM45", "gene_name": "TRIM45", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTRPGVNDKIRFCPQEKAGQCRGYEIYGTINTKEVDPAKCVLQGEDLHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVRRKHRPHSGVFHCCTFCSSGGQKTARCACGGTMPGGYLGCGHGHKGHPGHPHWSCCGKFNEKSECTWTGGQSAPRSLLRTVAL", "length": 580 }, "evidence": [ { "id": "A0A8V0ZIL2", "url": "https://omabrowser.org/oma/group/A0A8V0ZIL2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of inflammatory response", "id": "GO:0050728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050728", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 126, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZIL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL2" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 54, "start_aa": "Cys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIL8-1", "uniprot_ac": "A0A8V0ZIL8", "uniprot_id": "A0A8V0ZIL8_CHICK", "mass": { "chemical_mass": 138574.0, "monoisotopic_mass": 138574.0 }, "refseq": { "ac": "XP_015148621", "name": "peregrin isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148621" }, "gene_names": [ { "name": "BRPF1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8" } ] }, { "name": "BRPF1", "type": "synonym", "evidence": [ { "id": "XP_015148621", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148621" } ] }, { "name": "peregrin", "type": "synonym", "evidence": [ { "id": "XP_015148621", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148621" } ] } ], "protein_names": [ { "name": "Bromodomain and PHD finger containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8/entry#names_and_taxonomy" } ] }, { "name": "peregrin isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015148621", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148621" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148621" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BRPF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8", "locus": { "chromosome": "12", "start_pos": 11656691, "end_pos": 11645486, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021528", "url": "https://www.ensembl.org/id/ENSGALG00010021528" } ] } } ], "crossref": [ { "id": "A0A8V0ZIL8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05512", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05512", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15676", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15676", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15701", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15701", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20156", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20156", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427590", "url": "https://www.ncbi.nlm.nih.gov/gene/427590", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIL8", "url": "https://www.orthodb.org/?gene=A0A8V0ZIL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKA0", "url": "https://www.orthodb.org/?gene=A0A8V0ZKA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793:SF85", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793:SF85", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6804758", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804758", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015148621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148621", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVDFDVKTFCHNLRATKPPYECPVGSCRKIYKSYSGIEYHLYHYDHDNPPPPQQPPLRKHKKKGRQGRAGAADKQSPNPSEASQSPGREVMTYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAAEEAPENGGSKENGESQAAAAAAAAPKSAKQKSKEKRKDSNHHHHHNASAGAAPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPGSVRRLPALSHSEGEEEDEEEEEEGKSWSSEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQRDTEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQVALEMQLTPFLILLRKTLEHLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFQTMKQNLEAYRYLNFDDFEEDFNLIINNCLKYNAKDTIFYRAAVRLREQGGVVLRQARRQAEKMGIDFETGMHFPHCVTVEEAQVQDIEDEDMRLLLSENQKHLPLEEQLKILLERLDEVNAGKQSIGRSRRAKMIKKEITVLRRKLAHPRDLGRDGLERHSSSARGVLQSHNPCEKDLQTDSAAEESSSQETGKGLGPNSSSTPAHEVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRDSQIAPGHGNSPIGPPQLPIMGSSQRQRKRGRSPRPSSSSDSDSDKSTEDAPMDLPANGFSSGSQPVKKSFLVYRNDCNLPRSSSDSESSSSSSSSAASDRTSTTPSKQGRGKPSFSRVNFPEDSSEDTSGTENESYSVGAGRGVGHSMVRKGIGRGAGWLSEDEDSSLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWWLPAPRRQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRAMQHRNKVQGEQSSDSSESD", "length": 1225, "header": "tr|A0A8V0ZIL8-1|A0A8V0ZIL8_CHICK Isoform 1 of Bromodomain and PHD finger containing 1 OS=Gallus gallus OX=9031 GN=BRPF1 PE=4 SV=1 CANONICAL=A0A8V0ZIL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8/entry#A0A8V0ZIL8-1", "sequence": { "sequence": "MGVDFDVKTFCHNLRATKPPYECPVGSCRKIYKSYSGIEYHLYHYDHDNPPPPQQPPLRKHKKKGRQGRAGAADKQSPNPSEASQSPGREVMTYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAAEEAPENGGSKENGESQAAAAAAAAPKSAKQKSKEKRKDSNHHHHHNASAGAAPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPGSVRRLPALSHSEGEEEDEEEEEEGKSWSSEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQRDTEDKNWALKEQLKSWQRLRHDLERARLLVELIRKREKLKRETIKVQQVALEMQLTPFLILLRKTLEHLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFQTMKQNLEAYRYLNFDDFEEDFNLIINNCLKYNAKDTIFYRAAVRLREQGGVVLRQARRQAEKMGIDFETGMHFPHCVTVEEAQVQDIEDEDMRLLLSENQKHLPLEEQLKILLERLDEVNAGKQSIGRSRRAKMIKKEITVLRRKLAHPRDLGRDGLERHSSSARGVLQSHNPCEKDLQTDSAAEESSSQETGKGLGPNSSSTPAHEVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRDSQIAPGHGNSPIGPPQLPIMGSSQRQRKRGRSPRPSSSSDSDSDKSTEDAPMDLPANGFSSGSQPVKKSFLVYRNDCNLPRSSSDSESSSSSSSSAASDRTSTTPSKQGRGKPSFSRVNFPEDSSEDTSGTENESYSVGAGRGVGHSMVRKGIGRGAGWLSEDEDSSLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWWLPAPRRQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRAMQHRNKVQGEQSSDSSESD", "length": 1225, "header": "tr|A0A8V0ZIL8-1|A0A8V0ZIL8_CHICK Isoform 1 of Bromodomain and PHD finger containing 1 OS=Gallus gallus OX=9031 GN=BRPF1 PE=4 SV=1 CANONICAL=A0A8V0ZIL8-1" }, "locus": { "chromosome": "12", "start_pos": 11656450, "end_pos": 11645600, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052217.1", "url": "https://www.ensembl.org/id/ENSGALT00010052217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031189.1", "url": "https://www.ensembl.org/id/ENSGALP00010031189.1" } ] } }, { "isoform_ac": "A0A8V0ZKA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8/entry#A0A8V0ZKA0-1", "sequence": { "sequence": "MGVDFDVKTFCHNLRATKPPYECPVGSCRKIYKSYSGIEYHLYHYDHDNPPPPQQPPLRKHKKKGRQGRAGAADKQSPNPSEASQSPGREVMTYAQAQRMVEVDLHGRVHRISIFDNLDVVSEDEEAAEEAPENGGSKENGESQAAAAAAAAPKSAKQKSKEKRKDSNHHHHHNASAGAAPKLPEVVYRELEQDTPDAPPRPTSYYRYIEKSAEELDEEVEYDMDEEDYIWLDIMNERRKTEGVSPIPQEIFEYLMDRLEKESYFESHNKGDPNALVDEDAVCCICNDGECQNSNVILFCDMCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRAVDCALCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQRGSGACIQCHKANCYTAFHVTCAQQAGLYMKMEPVRETGANGTSFSVRKTAYCDIHTPPGSVRRLPALSHSEGEEEDEEEEEEGKSWSSEKVKKAKAKSRIKMKKARKILAEKRAAAPVVSVPCIPPHRLSKITNRLTIQRKSQFMQRLHSYWTLKRQSRNGVPLLRRLQTHLQSQRNCDQIKVQQVALEMQLTPFLILLRKTLEHLQEKDTGNIFSEPVPLSEVTEIYEVPDYLDHIKKPMDFQTMKQNLEAYRYLNFDDFEEDFNLIINNCLKYNAKDTIFYRAAVRLREQGGVVLRQARRQAEKMGIDFETGMHFPHCVTVEEAQVQDIEDEDMRLLLSENQKHLPLEEQLKILLERLDEVNAGKQSIGRSRRAKMIKKEITVLRRKLAHPRDLGRDGLERHSSSARGVLQSHNPCEKDLQTDSAAEESSSQETGKGLGPNSSSTPAHEVGRRTSVLFSKKNPKTAGPPKRPGRPPKNRDSQIAPGHGNSPIGPPQLPIMGSSQRQRKRGRSPRPSSSSDSDSDKSTEDAPMDLPANGFSSGSQPVKKSFLVYRNDCNLPRSSSDSESSSSSSSSAASDRTSTTPSKQGRGKPSFSRVNFPEDSSEDTSGTENESYSVGAGRGVGHSMVRKGIGRGAGWLSEDEDSSLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLKLGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEGRKSNIRKSVQIAYHRAMQHRNKVQGEQSSDSSESD", "length": 1180, "header": "tr|A0A8V0ZKA0-1|A0A8V0ZKA0_CHICK Computationally mapped isoform of Bromodomain and PHD finger containing 1 OS=Gallus gallus OX=9031 GN=BRPF1 PE=4 SV=1 CANONICAL=A0A8V0ZIL8-1" }, "locus": { "chromosome": "12", "start_pos": 11656450, "end_pos": 11645600, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052210.1", "url": "https://www.ensembl.org/id/ENSGALT00010052210.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031182.1", "url": "https://www.ensembl.org/id/ENSGALP00010031182.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 884, "start_aa": "Thr", "end_pos": 884, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr884", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6804758", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6804758", "resource": "Reactome", "description": "Regulation of TP53 Activity through Acetylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "histone H4K12 acetyltransferase activity", "id": "GO:0043997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043997", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8" } ], "pmid": "" }, { "name": "histone H4K5 acetyltransferase activity", "id": "GO:0043995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8" } ], "pmid": "" }, { "name": "histone H4K8 acetyltransferase activity", "id": "GO:0043996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043996", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8" } ], "pmid": "" }, { "name": "acetyltransferase activator activity", "id": "GO:0010698", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010698", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8" } ], "pmid": "" }, { "name": "histone reader activity", "id": "GO:0140566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140566", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL8" } ], "pmid": "" }, { "name": "MOZ/MORF histone acetyltransferase complex", "id": "GO:0070776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070776", 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member 18", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TNFRSF18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN1", "locus": { "chromosome": "21", "start_pos": 2559828, "end_pos": 2553443, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021538", "url": "https://www.ensembl.org/id/ENSGALG00010021538" } ] } } ], "crossref": [ { "id": "A0A8V0ZIN1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIN1", "database": "AlphaFoldDB", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZIN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERKLELHWPKGLLSIPARMMLSLAEKSSGSILRADWINVFHVCQPVRLRVKCITVTKATLNSLSFFTGDNSPCKETEDIDCKCPQGFSCADRSCTSCKKTECPEGKELVKLGIIQYTYSCKPCENGTYSNGKNSWCQSWTDCESSGLLTIKQGNSTHNSLCGYLVKYLDQDNITHDSLYTTILAILTAVGLFVLILLTFFLHLCIWSLKKEKHPAVDSVEHTFPRLPLAPQPSHHREETYSCQFPEEEHGDKILEEKPYYFQPPSLH", "length": 268, "header": "tr|A0A8V0ZIN1-1|A0A8V0ZIN1_CHICK Isoform 1 of TNF receptor superfamily member 18 OS=Gallus gallus OX=9031 GN=TNFRSF18 PE=4 SV=1 CANONICAL=A0A8V0ZIN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN1/entry#A0A8V0ZIN1-1", "sequence": { "sequence": "MERKLELHWPKGLLSIPARMMLSLAEKSSGSILRADWINVFHVCQPVRLRVKCITVTKATLNSLSFFTGDNSPCKETEDIDCKCPQGFSCADRSCTSCKKTECPEGKELVKLGIIQYTYSCKPCENGTYSNGKNSWCQSWTDCESSGLLTIKQGNSTHNSLCGYLVKYLDQDNITHDSLYTTILAILTAVGLFVLILLTFFLHLCIWSLKKEKHPAVDSVEHTFPRLPLAPQPSHHREETYSCQFPEEEHGDKILEEKPYYFQPPSLH", "length": 268, "header": "tr|A0A8V0ZIN1-1|A0A8V0ZIN1_CHICK Isoform 1 of TNF receptor superfamily member 18 OS=Gallus gallus OX=9031 GN=TNFRSF18 PE=4 SV=1 CANONICAL=A0A8V0ZIN1-1" }, "locus": { "chromosome": "21", "start_pos": 2557685, "end_pos": 2554930, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052238.1", "url": "https://www.ensembl.org/id/ENSGALT00010052238.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031205.1", "url": "https://www.ensembl.org/id/ENSGALP00010031205.1" } ] } }, { "isoform_ac": "A0A8V0ZK87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN1/entry#A0A8V0ZK87-1", "sequence": { "sequence": "MTVRRREVCLLNTRVCLLLAMYLWHWVPQTLATSCPSGELRTVAKDVKKCCPKCLSSSGDNSPCKETEDIDCKCPQGFSCADRSCTSCKKTECPEGKELVKLGIIQYTYSCKPCENGTYSNGKNSWCQSWTDCESSGLLTIKQGNSTHNSLCGYLVKYLDQDNITHDSLYTTILAILTAVGLFVLILLTFFLHLCIWSLKKEKHPAVDSVEHTFPRLPLAPQPSHHREETYSCQFPEEEHGDKILEEKPYYFQPPSLH", "length": 258, "header": "tr|A0A8V0ZK87-1|A0A8V0ZK87_CHICK Computationally mapped isoform of TNF receptor superfamily member 18 OS=Gallus gallus OX=9031 GN=TNFRSF18 PE=4 SV=1 CANONICAL=A0A8V0ZIN1-1" }, "locus": { "chromosome": "21", "start_pos": 2557685, "end_pos": 2553654, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052242.1", "url": "https://www.ensembl.org/id/ENSGALT00010052242.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031207.1", "url": "https://www.ensembl.org/id/ENSGALP00010031207.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419424", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419424", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F7FFS7-1", "protein_name": "TNF receptor superfamily member 18", "gene_name": "Tnfrsf18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGNWRWSWPGAQSEGWGQRQRQRQNMLERELLKSANRRLGRSTMGAWAMLYGVSLICVLDLGQQSIAEEPSCGPGRVRNGTGTNTRCCSLCGPDKEDCPKGRCICVKPEYHCEDPQCKTCKHYPCQPGQRVESQGNIKFGFQCVDCAMGTFSAGREGHCRLWTNCSQFGFLTVFPGNKTHNAVCIPEPLPTEQYGHLTVIFLVMAACILFLTTVQLGLHIWQLRRQHTCPRDTQPLLEVQLPPAEDACSFQFPEEERGEQMEEKCRLGDRWP", "length": 274 }, "evidence": [ { "id": "A0A8V0ZIN1", "url": "https://omabrowser.org/oma/group/A0A8V0ZIN1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35714-1", "protein_name": "Tumor necrosis factor receptor superfamily member 18", "gene_name": "Tnfrsf18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAWAMLYGVSMLCVLDLGQPSVVEEPGCGPGKVQNGSGNNTRCCSLYAPGKEDCPKERCICVTPEYHCGDPQCKICKHYPCQPGQRVESQGDIVFGFRCVACAMGTFSAGRDGHCRLWTNCSQFGFLTMFPGNKTHNAVCIPEPLPTEQYGHLTVIFLVMAACIFFLTTVQLGLHIWQLRRQHMCPRETQPFAEVQLSAEDACSFQFPEEERGEQTEEKCHLGGRWP", "length": 228 }, "evidence": [ { "id": "A0A8V0ZIN1", "url": "https://omabrowser.org/oma/group/A0A8V0ZIN1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5U5-1", "protein_name": "Tumor necrosis factor receptor superfamily member 18", "gene_name": "TNFRSF18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLLTSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV", "length": 241 }, "evidence": [ { "id": "A0A8V0ZIN1", "url": "https://omabrowser.org/oma/group/A0A8V0ZIN1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN1" } ], "pmid": "" }, { "name": "positive regulation of cell adhesion", "id": "GO:0045785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tumor necrosis factor receptor activity", "id": "GO:0005031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 173, "end_pos": 175 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIP1-1", "uniprot_ac": "A0A8V0ZIP1", "uniprot_id": "A0A8V0ZIP1_CHICK", "mass": { "chemical_mass": 241511.0, "monoisotopic_mass": 241511.0 }, "refseq": {}, "gene_names": [ { "name": "KIAA1549L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP1" } ] } ], "protein_names": [ { "name": "KIAA1549 like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA1549L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP1", "locus": { "chromosome": "5", "start_pos": 6438178, "end_pos": 6547078, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022569", "url": "https://www.ensembl.org/id/ENSGALG00010022569" } ] } } ], "crossref": [ { "id": "IPR024606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIP1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP10", "url": "https://www.orthodb.org/?gene=A0A8V0ZP10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21590:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21590:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12877", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12877", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQTLENANLLQMIKTTLTGTRTRTLDQTNLSPTLYQGSGNSASQEPAEVSAESLLRLSSQDADETAGESGLPQLGMFATLSTIPSVTHLSTAVPFQLTPLETPSISKESTSGPDMLAAVPSPSFSSLAVQSPHTINFSKSAVLAFKVPLSAEPESSFNTDSTSSQVSESRSSPLSVVSDVNSSMVNQGEGPELLTDTMSFNLSGSTVHFTNTVGKEFPSGRTSFLSEYSNTPVPKILHQFSMPVTSRSVLWFLYESMRNVSSTGVKPNSQPFKPLLIGRNNDVTPLSSPVFQNKAEVPALFFHPVGTPHKMPQMSHQSSTALTNCATGSTTAPFMSSASESLAEVSSSTESMSSLLLPKSFIPDAKHAHDAVLPGPAFRSETDFLFRNAAHSSSTSTMSPLLTETNETSARIALTNSPSTATANKGILQIPLTVFSQRSVVFLNQALAEDLTNGAHEANGMLLPSASARTVPYSDGSPVTRTTQQFLTRSVTAKISTDLNPNFVLPYGSQLSKLSPDIHVSKLSKQLKLPGTALETGMAAPGLAAITGLSNPELAVTNTSATTSISGTAHLPPFDADRTASDEDRSIGVPTVVTTHADYPPPRTLTHSHFTSGQTSRSIDTLQLVSFVPPARTTLPSFVSMTTARDSHSSGFSGISSAASESNLAPISSPKLTVSPSVWTNTVSLSSADTGISLVKNSIGTAVREVPLSTSTSATEYRSLYSVVSDLQKETRTNNQPLFFAPFAEYMHAMSSQNVSHLPFTGAKLDSFPEFVIDGFALKTSPVPYPSLATVVPASLQEKNGNTAENVTDFFTAGDINISAQYEAPLRLHVPHVNDAGVFPSSLESQTAGAGKMTLLAKTFSTTPALAFQLPDNLSLSAGYEIGAAHSRLPTKPPVSVSKPFSSALIRSSVTEEDTGSGNLEFIDSQLESSGYLVMADKNPATLSVEEWDTSAARQSLDPTSVSSKATTGMPLQTPSLSALQSVIITSVHPLPTQLTSAFFPTTNFTHSVITVLSGVSSGAIPTVGTSEAKPLTRKSSPASPVPASSFLSLGTENTPLPSVMALNTPVLTLIKNNTATKLTSVLSSVGAHTDLPSATRNTAASPVDMTAMFITSKSSTVMAPTLAPTAHVPRQIKTTVTDSQKFPSSEITKTSTPYPLTITAALTSITASAKATRLPPTRVENTSAPSETTAAAAFANMTAAPPLDCRLSWNLMVKTVLFLNTRRMMISKSFKESVTRGLNQALRQAFNQNVSTQVEILEQSSNITVGYYVTRGRLVFIPAAVVERLIAYGISNATADLKQHILSLQSIVALAMPWKPLPAYHFQLKTELQFVSQTDNIQSCRFVQTMEQRLQRAFQDAERKVWNTSNNLTVQILNTSKVSQAVTLFYVVNNQSTTLNGTISSNLLNQLSAELVGFYLTYPPLTIAESLEYPNLDVSESTRDYWVITVIQGVDIALLGLNNQSFARLMEQRLAPLFMMSHQQGRRFKRATTVGSYTVQMVKIQRIPGPKEPAELTYYTLYNGKPLLGTAAAKILSTVDSQRMALTLGYVIQVQADPVVKNPPNNLWIIAAVLAPIAVVTVIIIIITAVLCRKNKNDFKPDTMMNLPQRAKPVQGFDYAKQHLGQQGAEDEVLPVTQETVVLPLPVRDAPASQEREITQDGSTIKTAQSNDTRKSRSPSQNGSIISNESGKPSSSRSSPQKVVAPPKVTKDEGRKRNGFKASKKIVPISDEEEGGILFDNIAKSAIDPFDTSSGSVQLIAIKPVALPAVHAASDRSQESAIINGEVNKALKQKSDIEHYRNKLRLKAKRKGYYDFPQVDNNKGLTDRKRMYEKNQKEIDHILDPDPDVSSPFAEPKNRQQMKNSIYRSRQSLNSPSPGETEMDLLVTRERPRRGIRNSGYDTEPEIIEETNVDRVTEPRSYTRSRQAKGHSETSTLSSQPSIDEVRQQMHMLLEEAFSLASAGHGGQSRQEAYSSAPHLPYSEVVTSAPGTMTRPRAGVQWVPTYRPEMYQYSLPRPAYRFSQLPEMVMGSPPPPVPPRTGPVAVASLRRSTSDIGSKVRIPESSGVDQAQHHDPASYAPGSRAPMSVGPLDQSAFHSGNTVPAVFAIPAANRPGFTGYFIPTPPTAYRNQAWMPYAGENELPGQWADSVPLPGYIEAYPRPRYQHNSPSRLPRQYSQSSSIHPSLEQAPLPSATASQQSLTENDPSDAPLTNISTAALVKAIREEVAKLAKKQTDMFEFQV", "length": 2241, "header": "tr|A0A8V0ZIP1-1|A0A8V0ZIP1_CHICK Isoform 1 of KIAA1549 like OS=Gallus gallus OX=9031 GN=KIAA1549L PE=4 SV=1 CANONICAL=A0A8V0ZIP1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP1/entry#A0A8V0ZIP1-1", "sequence": { "sequence": "MGQTLENANLLQMIKTTLTGTRTRTLDQTNLSPTLYQGSGNSASQEPAEVSAESLLRLSSQDADETAGESGLPQLGMFATLSTIPSVTHLSTAVPFQLTPLETPSISKESTSGPDMLAAVPSPSFSSLAVQSPHTINFSKSAVLAFKVPLSAEPESSFNTDSTSSQVSESRSSPLSVVSDVNSSMVNQGEGPELLTDTMSFNLSGSTVHFTNTVGKEFPSGRTSFLSEYSNTPVPKILHQFSMPVTSRSVLWFLYESMRNVSSTGVKPNSQPFKPLLIGRNNDVTPLSSPVFQNKAEVPALFFHPVGTPHKMPQMSHQSSTALTNCATGSTTAPFMSSASESLAEVSSSTESMSSLLLPKSFIPDAKHAHDAVLPGPAFRSETDFLFRNAAHSSSTSTMSPLLTETNETSARIALTNSPSTATANKGILQIPLTVFSQRSVVFLNQALAEDLTNGAHEANGMLLPSASARTVPYSDGSPVTRTTQQFLTRSVTAKISTDLNPNFVLPYGSQLSKLSPDIHVSKLSKQLKLPGTALETGMAAPGLAAITGLSNPELAVTNTSATTSISGTAHLPPFDADRTASDEDRSIGVPTVVTTHADYPPPRTLTHSHFTSGQTSRSIDTLQLVSFVPPARTTLPSFVSMTTARDSHSSGFSGISSAASESNLAPISSPKLTVSPSVWTNTVSLSSADTGISLVKNSIGTAVREVPLSTSTSATEYRSLYSVVSDLQKETRTNNQPLFFAPFAEYMHAMSSQNVSHLPFTGAKLDSFPEFVIDGFALKTSPVPYPSLATVVPASLQEKNGNTAENVTDFFTAGDINISAQYEAPLRLHVPHVNDAGVFPSSLESQTAGAGKMTLLAKTFSTTPALAFQLPDNLSLSAGYEIGAAHSRLPTKPPVSVSKPFSSALIRSSVTEEDTGSGNLEFIDSQLESSGYLVMADKNPATLSVEEWDTSAARQSLDPTSVSSKATTGMPLQTPSLSALQSVIITSVHPLPTQLTSAFFPTTNFTHSVITVLSGVSSGAIPTVGTSEAKPLTRKSSPASPVPASSFLSLGTENTPLPSVMALNTPVLTLIKNNTATKLTSVLSSVGAHTDLPSATRNTAASPVDMTAMFITSKSSTVMAPTLAPTAHVPRQIKTTVTDSQKFPSSEITKTSTPYPLTITAALTSITASAKATRLPPTRVENTSAPSETTAAAAFANMTAAPPLDCRLSWNLMVKTVLFLNTRRMMISKSFKESVTRGLNQALRQAFNQNVSTQVEILEQSSNITVGYYVTRGRLVFIPAAVVERLIAYGISNATADLKQHILSLQSIVALAMPWKPLPAYHFQLKTELQFVSQTDNIQSCRFVQTMEQRLQRAFQDAERKVWNTSNNLTVQILNTSKVSQAVTLFYVVNNQSTTLNGTISSNLLNQLSAELVGFYLTYPPLTIAESLEYPNLDVSESTRDYWVITVIQGVDIALLGLNNQSFARLMEQRLAPLFMMSHQQGRRFKRATTVGSYTVQMVKIQRIPGPKEPAELTYYTLYNGKPLLGTAAAKILSTVDSQRMALTLGYVIQVQADPVVKNPPNNLWIIAAVLAPIAVVTVIIIIITAVLCRKNKNDFKPDTMMNLPQRAKPVQGFDYAKQHLGQQGAEDEVLPVTQETVVLPLPVRDAPASQEREITQDGSTIKTAQSNDTRKSRSPSQNGSIISNESGKPSSSRSSPQKVVAPPKVTKDEGRKRNGFKASKKIVPISDEEEGGILFDNIAKSAIDPFDTSSGSVQLIAIKPVALPAVHAASDRSQESAIINGEVNKALKQKSDIEHYRNKLRLKAKRKGYYDFPQVDNNKGLTDRKRMYEKNQKEIDHILDPDPDVSSPFAEPKNRQQMKNSIYRSRQSLNSPSPGETEMDLLVTRERPRRGIRNSGYDTEPEIIEETNVDRVTEPRSYTRSRQAKGHSETSTLSSQPSIDEVRQQMHMLLEEAFSLASAGHGGQSRQEAYSSAPHLPYSEVVTSAPGTMTRPRAGVQWVPTYRPEMYQYSLPRPAYRFSQLPEMVMGSPPPPVPPRTGPVAVASLRRSTSDIGSKVRIPESSGVDQAQHHDPASYAPGSRAPMSVGPLDQSAFHSGNTVPAVFAIPAANRPGFTGYFIPTPPTAYRNQAWMPYAGENELPGQWADSVPLPGYIEAYPRPRYQHNSPSRLPRQYSQSSSIHPSLEQAPLPSATASQQSLTENDPSDAPLTNISTAALVKAIREEVAKLAKKQTDMFEFQV", "length": 2241, "header": "tr|A0A8V0ZIP1-1|A0A8V0ZIP1_CHICK Isoform 1 of KIAA1549 like OS=Gallus gallus OX=9031 GN=KIAA1549L PE=4 SV=1 CANONICAL=A0A8V0ZIP1-1" }, "locus": { "chromosome": "5", "start_pos": 6508106, "end_pos": 6446604, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054928.1", "url": "https://www.ensembl.org/id/ENSGALT00010054928.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033209.1", "url": "https://www.ensembl.org/id/ENSGALP00010033209.1" } ] } }, { "isoform_ac": "A0A8V0ZP10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP1/entry#A0A8V0ZP10-1", "sequence": { "sequence": "MGQTLENANLLQMIKTTLTGTRTRTLDQTNLSPTLYQGSGNSASQEPAEVSAESLLRLSSQDADETAGESGLPQLGMFATLSTIPSVTHLSTAVPFQLTPLETPSISKESTSGPDMLAAVPSPSFSSLAVQSPHTINFSKSAVLAFKVPLSAEPESSFNTDSTSSQVSESRSSPLSVVSDVNSSMVNQGEGPELLTDTMSFNLSGSTVHFTNTVGKEFPSGRTSFLSEYSNTPVPKILHQFSMPVTSRSVLWFLYESMRNVSSTGVKPNSQPFKPLLIGRNNDVTPLSSPVFQNKAEVPALFFHPVGTPHKMPQMSHQSSTALTNCATGSTTAPFMSSASESLAEVSSSTESMSSLLLPKSFIPDAKHAHDAVLPGPAFRSETDFLFRNAAHSSSTSTMSPLLTETNETSARIALTNSPSTATANKGILQIPLTVFSQRSVVFLNQALAEDLTNGAHEANGMLLPSASARTVPYSDGSPVTRTTQQFLTRSVTAKISTDLNPNFVLPYGSQLSKLSPDIHVSKLSKQLKLPGTALETGMAAPGLAAITGLSNPELAVTNTSATTSISGTAHLPPFDADRTASDEDRSIGVPTVVTTHADYPPPRTLTHSHFTSGQTSRSIDTLQLVSFVPPARTTLPSFVSMTTARDSHSSGFSGISSAASESNLAPISSPKLTVSPSVWTNTVSLSSADTGISLVKNSIGTAVREVPLSTSTSATEYRSLYSVVSDLQKETRTNNQPLFFAPFAEYMHAMSSQNVSHLPFTGAKLDSFPEFVIDGFALKTSPVPYPSLATVVPASLQEKNGNTAENVTDFFTAGDINISAQYEAPLRLHVPHVNDAGVFPSSLESQTAGAGKMTLLAKTFSTTPALAFQLPDNLSLSAGYEIGAAHSRLPTKPPVSVSKPFSSALIRSSVTEEDTGSGNLEFIDSQLESSGYLVMADKNPATLSVEEWDTSAARQSLDPTSVSSKATTGMPLQTPSLSALQSVIITSVHPLPTQLTSAFFPTTNFTHSVITVLSGVSSGAIPTVGTSEAKPLTRKSSPASPVPASSFLSLGTENTPLPSVMALNTPVLTLIKNNTATKLTSVLSSVGAHTDLPSATRNTAASPVDMTAMFITSKSSTVMAPTLAPTAHVPRQIKTTVTDSQKFPSSEITKTSTPYPLTITAALTSITASAKATRLPPTRVENTSAPSETTAAAAFANMTAAPPLDCRLSWNLMVKTVLFLNTRRMMISKSFKESVTRGLNQALRQAFNQNVSTQVEILEQSSNITVGYYVTRGRLVFIPAAVVERLIAYGISNATADLKQHILSLQSIVALAMPWKPLPAYHFQLKTELQFVSQTDNIQSCRFVQTMEQRLQRAFQDAERKVWNTSNNLTVQILNTSKVSQAVTLFYVVNNQSTTLNGTISSNLLNQLSAELVGFYLTYPPLTIAESLEYPNLDVSESTRDYWVITVIQGVDIALLGLNNQSFARLMEQRLAPLFMMSHQQGRRFKRATTVGSYTVQMVKIQRIPGPKEPAELTYYTLYNGKPLLGTAAAKILSTVDSQRMALTLGYVIQVQADPVVKNPPNNLWIIAAVLAPIAVVTVIIIIITAVLCRKNKNDFKPDTMMNLPQRAKPVQGFDYAKQHLGQQGAEDEVLPVTQETVVLPLPVRDAPASQEREITQDGSTIKTAQSNDTRKSRSPSQNGSIISNESGKPSSSRSSPQKVVAPPKVTKDEGRKRNVPISDEEEGGILFDNIAKSAIDPFDTSSGSVQLIAIKPVALPAVHAASDRSQESAIINGEVNKALKQKSDIEHYRNKLRLKAKRKGYYDFPQVDNNKGLTDRKRMYEKNQKEIDHILDPDPDVSSPFAEPKNRQQMKNSIYRSRQSLNSPSPGETEMDLLVTRERPRRGIRNSGYDTEPEIIEETNVDRVTEPRSYTRSRQAKGHSETSTLSSQPSIDEVRQQMHMLLEEAFSLASAGHGGQSRQEAYSSAPHLPYSEVVTSAPGTMTRPRAGVQWVPTYRPEMYQYSLPRPAYRFSQLPEMVMGSPPPPVPPRTGPVAVASLRRSTSDIGSKVRIPESSGVDQAQHHDPASYAPGSRAPMSVGPLDQSAFHSGNTVPAVFAIPAANRPGFTGYFIPTPPTAYRNQAWMPYAGENELPGQWADSVPLPGYIEAYPRPRYQHNSPSRLPRQYSQSSSIHPSLEQAPLPSATASQQSLTENDPSDAPLTNISTAALVKAIREEVAKLAKKQTDMFEFQV", 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIR8-1", "uniprot_ac": "A0A8V0ZIR8", "uniprot_id": "A0A8V0ZIR8_CHICK", "mass": { "chemical_mass": 60159.0, "monoisotopic_mass": 60159.0 }, "refseq": {}, "gene_names": [ { "name": "TCP11L1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR8" } ] } ], "protein_names": [ { "name": "T-complex 11 like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TCP11L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIR8", "locus": { "chromosome": "5", "start_pos": 6682423, "end_pos": 6698694, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022588", "url": "https://www.ensembl.org/id/ENSGALG00010022588" } ] } } ], "crossref": [ { "id": "A0A8V0ZIR8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIR8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIR8", "url": "https://www.orthodb.org/?gene=A0A8V0ZIR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12832:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12832:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIS5-1", "uniprot_ac": "A0A8V0ZIS5", "uniprot_id": "A0A8V0ZIS5_CHICK", "mass": { "chemical_mass": 41817.0, "monoisotopic_mass": 41817.0 }, "refseq": { "ac": "XP_015151771", "name": "homeobox protein TGIF2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151771" }, "gene_names": [ { "name": "TGIF2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIS5", "database": 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015151771.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151771", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151771" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TGIF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS5", "locus": { "chromosome": "20", "start_pos": 786384, "end_pos": 793691, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021561", "url": "https://www.ensembl.org/id/ENSGALG00010021561" } ] } } ], "crossref": [ { "id": "A0A8V0ZIS5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": 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], "sequence": { "sequence": "MAASPGRFLPGPNPPAQRCRRLHAPSSRPPPRPPPVPPAVSAPVGARLGQAALRRAPAGSPFLASKNTNSTATGGEGRRERRPSGAGCPAALSVRLHPLRHCPSDCFPNGRSLTALSCQWARRGSKQDRAAGSPAMSDSDLGEDDGAAALDPSQSNKRKRRGNLPKESVRILREWLYEHRFNAYPSEQEKLSLSGQTSLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKAGDVTLPRGAAAGSGMLVVPPVTAGGAAKVLPISMCPQVLCHPTQALGGNLAVLGAHSPEREKQPGLQRVEPDPHPKAPPGAAGSTVALLARAEAASPTSGLFNTPPPTPPELFGDDFSSFQLLVEVALQKAAELESQRQGGQLPLSPQTEPPGASVAK", "length": 397, "header": "tr|A0A8V0ZIS5-1|A0A8V0ZIS5_CHICK Isoform 1 of TGFB induced factor homeobox 2 OS=Gallus gallus OX=9031 GN=TGIF2 PE=3 SV=1 CANONICAL=A0A8V0ZIS5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS5/entry#A0A8V0ZIS0-1", "sequence": { "sequence": "MQGPRRRRRRPGGSKQDRAAGSPAMSDSDLGEDDGAAALDPSQSNKRKRRGNLPKESVRILREWLYEHRFNAYPSEQEKLSLSGQTSLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKAGDVTLPRGAAAGSGMLVVPPVTAGGAAKVLPISMCPQVLCHPTQALGGNLAVLGAHSPEREKQPGLQRVEPDPHPKAPPGAAGSTVALLARAEAASPTSGLFNTPPPTPPELFGDDFSSFQLLVEVALQKAAELESQRQGGQLPLSPQTEPPGASVAK", "length": 286, "header": "tr|A0A8V0ZIS0-1|A0A8V0ZIS5_CHICK Computationally mapped isoform of TGFB induced factor homeobox 2 OS=Gallus gallus OX=9031 GN=TGIF2 PE=3 SV=1 CANONICAL=A0A8V0ZIS5-1" }, "locus": { "chromosome": "20", "start_pos": 792091, "end_pos": 788541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052309.1", "url": "https://www.ensembl.org/id/ENSGALT00010052309.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031250.1", "url": "https://www.ensembl.org/id/ENSGALP00010031250.1" } ] } }, { "isoform_ac": "A0A8V0ZIS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS5/entry#A0A8V0ZIS5-1", "sequence": { "sequence": "MAASPGRFLPGPNPPAQRCRRLHAPSSRPPPRPPPVPPAVSAPVGARLGQAALRRAPAGSPFLASKNTNSTATGGEGRRERRPSGAGCPAALSVRLHPLRHCPSDCFPNGRSLTALSCQWARRGSKQDRAAGSPAMSDSDLGEDDGAAALDPSQSNKRKRRGNLPKESVRILREWLYEHRFNAYPSEQEKLSLSGQTSLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKAGDVTLPRGAAAGSGMLVVPPVTAGGAAKVLPISMCPQVLCHPTQALGGNLAVLGAHSPEREKQPGLQRVEPDPHPKAPPGAAGSTVALLARAEAASPTSGLFNTPPPTPPELFGDDFSSFQLLVEVALQKAAELESQRQGGQLPLSPQTEPPGASVAK", "length": 397, "header": "tr|A0A8V0ZIS5-1|A0A8V0ZIS5_CHICK Isoform 1 of TGFB induced factor homeobox 2 OS=Gallus gallus OX=9031 GN=TGIF2 PE=3 SV=1 CANONICAL=A0A8V0ZIS5-1" }, "locus": { "chromosome": "20", "start_pos": 793492, "end_pos": 788541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052317.1", "url": "https://www.ensembl.org/id/ENSGALT00010052317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031255.1", "url": "https://www.ensembl.org/id/ENSGALP00010031255.1" } ] } }, { "isoform_ac": "A0A8V0ZKD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS5/entry#A0A8V0ZKD0-1", "sequence": { "sequence": "MSDSDLGEDDGAAALDPSQSNKRKRRGNLPKESVRILREWLYEHRFNAYPSEQEKLSLSGQTSLSVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKAGDVTLPRGAAAGSGMLVVPPVTAGGAAKVLPISMCPQVLCHPTQALGGNLAVLGAHSPEREKQPGLQRVEPDPHPKAPPGAAGSTVALLARAEAASPTSGLFNTPPPTPPELFGDDFSSFQLLVEVALQKAAELESQRQGGQLPLSPQTEPPGASVAK", "length": 262, "header": "tr|A0A8V0ZKD0-1|A0A8V0ZKD0_CHICK Computationally mapped isoform of TGFB induced factor homeobox 2 OS=Gallus gallus OX=9031 GN=TGIF2 PE=3 SV=1 CANONICAL=A0A8V0ZIS5-1" }, "locus": { "chromosome": "20", "start_pos": 791240, "end_pos": 788541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052314.1", "url": "https://www.ensembl.org/id/ENSGALT00010052314.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031252.1", "url": "https://www.ensembl.org/id/ENSGALP00010031252.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIT5-1", "uniprot_ac": "A0A8V0ZIT5", "uniprot_id": "A0A8V0ZIT5_CHICK", "mass": { "chemical_mass": 701278.0, "monoisotopic_mass": 701278.0 }, "refseq": {}, "gene_names": [ { "name": "AHNAK2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT5" } ] } ], "protein_names": [ { "name": "AHNAK nucleoprotein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AHNAK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT5", "locus": {} } ], "crossref": [ { "id": "IPR052082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIT5", "url": "https://www.orthodb.org/?gene=A0A8V0ZIT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23348:SF41", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23348:SF41", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTEELNETSTKNLKDGENGIPTYAKKCPEVEISIKKEKEKESTLKYTVTEVQDVKRKESKPSLEADLKETPMKQTPKTSSKSRKKKQKGTEDKTEGENGIKGDTMDHTAEVYIEERGLEIGRARAELQSTETQETREKQGEEDKQVPTIQKTKFWMSVSKRKETDTKKILTKPEIDVADSGLETQAEKEIEKGRKMEVEAQIASTETEESTRKITLPSIEMAILPVDDKTIQDTKVESKYKLNKEQTEERNIQTSDRSSNIEITAKKAEKDADGKESKQRLPKFKLPTFTWGTTKDETMKSDIQVSEPMTAKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAVGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTAEVDVTLPGKGRFKMPDVKMPSVELPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTAEVDVTLPGAEIQAPGVEVTIEAALPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTMPSVKLPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQVPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTMPSVKLPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTMPSVKLPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTMPSVKLPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTMPSVKLPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTAKVDMPSVKLPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTMPSVKLPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTMPSVKLPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTMPSVKLPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTMPSVKLPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTMPSVKLPKVKAPHVQVSLPKAEISLPKAQGEIPEGELALQGPDAEGSLDVAAGKAEGGGMKLHMPKVKVPSVAFSKPTVKAPKVEVDVSVPKVDASLPEAEVKAGAVDVSISAPDIKPPSVEGSLDLQAPKVDLKVPSAEGSLDGGELEAAGLKGKFKMPKFDKPKFGVSVPKAEGPEGEVSLPTAEVELPSGTVTVTGEGPSLDLKADTGGAKTEGAGWKLEKPSLKMPKADIKAPKVDISLPSVDITLPKAGVDLQAPEAALSLEGEAKAPEKEATKAKDGKFKMPKFGMPSFGWSSSREAKGTVAADVDVSLKEPQVTAPSGTAEVDVTLPGAEIQPPDIAFISSSSSVKEESTSKSKVSFFSMPRVLLSRSSKHELQSKSNIECSESESMCYSVTEESPAVISGSVGSKLVPDVKGDSSSKSTKFRIPSLGFSKVDISSSKFEQDSPLSKGDVTLTKYQMNAAESESKISSSADVKISFTDLEILNGEGSYEQGITKPEGVKTPPAELSGGDIEYTVKIPKFRKPKFGFSWSKGKPSESDIGSKVESEFSTEKMTSEMFDIENPSQIPESEFGLKMQKTSPEFVTGASKLDVSLPSPEITLPKLEMDIHDPECRKEQELISGKKDTEEKESKFKMSKFKLLSFNWSPKKEAIAPSEAEGHLEESTILSGDTESKLAPIIPENQDLHVELDTATEKHGEMGKTKKSQFIMPKISLTKVMGQKVQGSLPVLETDVCDLKQEKCGDDSVQKSDKGSSGERAEIAVKMSKVKVSAPEFSKPAVEGPKIEMDISMPAGEVILTSCEQDELTLKSAADDIPSSDTKMTIEASLEVKSPETSVERISSEIAMSGVEIKVEGPEGKTKMSKFQMPKFGMTHSKGKGSEKEVSQTKSEAKVPQIKAMIEIADIAVEAPNLEVECGEGTESSSSKLKITKDDKKAPEVDTHFPTGEISISKTDSDIQDSDMALKIKEETKHRNEDGEEKEGHFKMPKLKLPSFSWSPKKEATVKEDSGGNLEDNKVAVMSGRIDTEAEGTVADDQGPRPAFDLEIPAGKDQQKSPIKKPQFVMPKISLSKIKIPKSQGHSSKVEAGSTVTKTERDGVDSVQIPDIEISHSTQIEEGAQISIKTAVVKIPTLELSKTEAFQANLGVSSAKIDAALTASEESFQQVVLKSSSDKDSIQRTGIEFPEGETSVELRSTKIATEGSLVMDGRKMKLEGHDVQIKMPKFQKPKFGISLTKGKGPEPEVSSPKLEAELPQLKMTAEAADIAARAPASEFTSDMSDPGLEVYASKAKTPQVLTAVIEAPKVDISPQSESKAVIEEDTEGLEEKEIKSEEETKAEEAQTEEHQGWFKMPKFRIPAFGRTSLKEKKGDADVERSLEKTQASIPSAKVQTEAEITIGKEEIPKLGDSMEISVISLPKVEGDISLSAERRDSRVNIQKTETYADIVKRGAEGQKMHSSEFTVSSVGLSEREISASIIDKDNSSPSKFPMGTLTLQEQKDKSQDIDTPEVESSTEVKTLSAEFKTSSGEITLDRTQEKIDASLPKGELDLQNQGAVIKTVKIRTSEMKITGKDSELKWSTGEWATAKGSENAVYIAAKMEDVKVDVPEVKTDVEIERVDPEMKCQVKRVEKDMSANVEAQVEDRAEISKIKTYKFKIPKFGVLHSEVKGFEDDISLPKSGAVSVTKTEIDRAEMQFQKSEGSIGPTSPTLDHMESSARITGETVDKSQDDPEVNIIIPKLKIPRFTFRVLPSEADVSLSKVVTDPKGTSADIEVVHLQTSSTIPEEIPETLEGDIQKAKSKILTLIEPDIKTAQMTATIDSCLSNAGQDIHWSYVEGQEVREKVEPEHVSIERCEIYSTQILKESEILSSEVKTATLGFSLLKAKLPESHSNSEVLVQQSPSMDNASVNKSEHSDESFAVTTQRTGTSELKLSDKPHSETEESRRMTGLPTLKTFAAEVKPFSKPEESHPDKAPEKITAAPLSKDGDITEAQEDEEKYVTNEKEKADSKRSPGRFKFWLPSIGFSSSGDETSSDSKTEVKKSEETRPEDMKPADTSVSDSSKQGEKTGWFRFPKLGFTSPSKKAKTVDKEETGHEERRISDEDSPSDKPDVFFDAQESLSPKEIIESEKQEIDGTSSNIPVSQTIVTSSARTELILLEEEKASQPNIPGDTTK", "length": 6687, "header": "tr|A0A8V0ZIT5-1|A0A8V0ZIT5_CHICK Isoform 1 of AHNAK nucleoprotein 2 OS=Gallus gallus OX=9031 GN=AHNAK2 PE=1 SV=1 CANONICAL=A0A8V0ZIT5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT5/entry#A0A8V0ZIT5-1", "sequence": { "sequence": 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"length": 6687, "header": "tr|A0A8V0ZIT5-1|A0A8V0ZIT5_CHICK Isoform 1 of AHNAK nucleoprotein 2 OS=Gallus gallus OX=9031 GN=AHNAK2 PE=1 SV=1 CANONICAL=A0A8V0ZIT5-1" }, "locus": { "chromosome": "5", "start_pos": 51336760, "end_pos": 51315266, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048315.1", "url": "https://www.ensembl.org/id/ENSGALT00010048315.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028488.1", "url": "https://www.ensembl.org/id/ENSGALP00010028488.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 6220, "start_aa": "Thr", "end_pos": 6220, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr6220", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5161, "end_pos": 5163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5996, "end_pos": 5998, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6419, "end_pos": 6421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6423, "end_pos": 6425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 6220 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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combination :: AJ719391.1, ERR2368565.183512.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000328.1. On Sep 23, 2021 this sequence version replaced NP_001073205.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001073205", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073205" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C20H20ORF24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV7", "locus": { "chromosome": "20", "start_pos": 808460, "end_pos": 804097, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021579", "url": "https://www.ensembl.org/id/ENSGALG00010021579" } ] } } ], "crossref": [ { "id": "A0A8V0ZIV7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIV7", "database": "AlphaFoldDB", 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"tr|A0A8V0ZIV7-1|A0A8V0ZIV7_CHICK Isoform 1 of Chromosome 20 open reading frame, human C20orf24 OS=Gallus gallus OX=9031 GN=C20H20ORF24 PE=1 SV=1 CANONICAL=A0A8V0ZIV7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV7/entry#A0A8V0ZIV7-1", "sequence": { "sequence": "MSGARRREEPPHAQQHALANGGGAGPRGSVWGKALRSDSAWHDKDEFLDVIYWFRQIIAVILGVIWGVVPLKGFVGIAIFCLINAGVLYLYFSSFQQIDEEEYGGTWELTKEGFMTSFALFLVVWIIFYTAIHYD", "length": 135, "header": "tr|A0A8V0ZIV7-1|A0A8V0ZIV7_CHICK Isoform 1 of Chromosome 20 open reading frame, human C20orf24 OS=Gallus gallus OX=9031 GN=C20H20ORF24 PE=1 SV=1 CANONICAL=A0A8V0ZIV7-1" }, "locus": { "chromosome": "20", "start_pos": 806711, "end_pos": 804153, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052363.1", "url": "https://www.ensembl.org/id/ENSGALT00010052363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031291.1", "url": "https://www.ensembl.org/id/ENSGALP00010031291.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768550", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768550", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A7K9-1", "protein_name": "RAB5 interacting factor", "gene_name": "RAB5IF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LQTPTPFRSARAPQPQLANGALKVSVWSKVLRSDAAWEDKDEFLDVIYWFRQIIAVVLGVIWGVLPLRGFLGIAGFCLINAGVLYLYFSNYLQIDEEEYGGTWELTKEGFMTSFALFMVIWIIFYTAIHYD", "length": 131 }, "evidence": [ { "id": "A0A8V0ZIV7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIV7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RD59-1", "protein_name": "GEL complex subunit OPTI", "gene_name": "rab5if", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSSSKRKEEIHAVNGGVKQSTWSKAISCKAVWEEKDEFLDVVYWFRQIIAIILGVIWGVAPLKGFLGIAIFCIINAGVLYVYFSSFQQVDEEEYGGTWELTKEGFMTSFALFLVVWIIFYTALHYD", "length": 127 }, "evidence": [ { "id": "A0A8V0ZIV7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIV7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q54I50-1", "protein_name": "Rab5-interacting protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSETKERSQLLLLKNSFNKDFKFTNKEIAQNVHWLRQIVSILVGIIVGSIPVIGFPGFIAFLIFTCGFVAIYYTKVLEIEEDDFKWELMREGFMSSLTIFVISWIIAYNSLYV", "length": 113 }, "evidence": [ { "id": "A0A8V0ZIV7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIV7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5FVK9-1", "protein_name": "RAB5 interacting factor", "gene_name": "Rab5if", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGGRRKEEPPQPQLANGALKVSVWSKVLRSDAAWDDKDEFLDVIYWFRQIIAVVLGVIWGILPLRGFLGIAGFCLINAGVLYLYFSNYLQIDEEEYGGTWELTKEGFMTSFALFMVIWIIFYTAIHYD", "length": 129 }, "evidence": [ { "id": "A0A8V0ZIV7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIV7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BUV8-1", "protein_name": "GEL complex subunit OPTI", "gene_name": "RAB5IF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGGRRKEEPPQPQLANGALKVSVWSKVLRSDAAWEDKDEFLDVIYWFRQIIAVVLGVIWGVLPLRGFLGIAGFCLINAGVLYLYFSNYLQIDEEEYGGTWELTKEGFMTSFALFMVCVADSFTTGHLDHLLHCHPL", "length": 137 }, "evidence": [ { "id": "A0A8V0ZIV7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIV7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQT9-1", "protein_name": "GEL complex subunit OPTI", "gene_name": "Rab5if", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGGRRKEEPPQPQLANGALKVSVWSKVLRSDAAWDDKDEFLDVIYWFRQIIALVLGVIWGVLPLRGFLGIAGFCLINAGVLYLYFSNYLQIDEEEYGGTWELTKEGFMTSFALFMVIWIIFYTAIHYD", "length": 129 }, "evidence": [ { "id": "A0A8V0ZIV7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIV7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV7" } ], "pmid": "" }, { "name": "multi-pass translocon complex", "id": "GO:0160064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial respirasome assembly", "id": "GO:0097250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097250", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV7" } ], "pmid": "" }, { "name": "multi-pass transmembrane protein insertion into ER membrane", "id": "GO:0160063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160063", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIX6-1", "uniprot_ac": "A0A8V0ZIX6", "uniprot_id": "A0A8V0ZIX6_CHICK", "mass": { "chemical_mass": 96434.0, "monoisotopic_mass": 96434.0 }, "refseq": {}, "gene_names": [ { "name": "OVCH2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX6" } ] } ], "protein_names": [ { "name": "Ovochymase 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OVCH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX6", "locus": { "chromosome": "5", "start_pos": 7089522, "end_pos": 7106727, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021584", "url": "https://www.ensembl.org/id/ENSGALG00010021584" } ] } } ], "crossref": [ { "id": "A0A8V0ZIX6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIX6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIX6", "url": "https://www.orthodb.org/?gene=A0A8V0ZIX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRB2", "url": "https://www.orthodb.org/?gene=A0A8V0ZRB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24252:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24252:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCITSSKLLLLLLGVVCITESRAVPHILQKDPKCGQKVHETKPWSYFNLFTRIVGGNQVKQGSHPWQVSLKRREKHFCGGTIVSAQWVVTAAHCVSDRADSTHFDCTYYTRKSEDERNLLKYLNVTAGEHDLRIRENGEQTLPVKYIIKHPNFDPRRPMNYDIALLKLDGTFNFSSSVLPACLPDPGEKFEAGYICTACGWGRLRENGVLPQVLYEVNLPILNSMECSRALSTLRKPIQGDTILCAGFPDGGKDACQGDSGGPLLCRRKHGAWILAGVISWGMGCARGWRGNEMKRHYERGSPGIFTDLSAVLSWIQENMSADLKMKSSTPFCSVQDGKLTDSEGELNFPGGSEQFYQNHQLCIWTLFVPEGNYILLHFSHFDIEPETFCDYDSLSVYSKDDRLVGKFCGGDLPLPILIGSNNIRLKFVSDNKDYGTGFSMTYKALTTGILPDSGCESLAVLFEEGVLQSMHYPENYSNLAVCQWIICAPEDHVIKLTYQTFEVEESEDCSYDAVTVYEDAGKEEEIAKSCGFVLPAPVLSSSSMMLVVFHSDETETFEGFRATITFVHVTDLDTLDSASVEVFENTDMTEEEIQVTTDDVCGMPSNQPRFIFSRIIGGEEAVPHSWPWQVSIQISDQHICGGAVLAKEWVITAAHCFNSKELYRDLWMVVTGIHDLTEQEYRQKRSVKQYIIHPSFNKTTMDSDIALLQLAEPLEFNHYVHPVCLPAKEEVVQPSSVCIITGWGAQEEDREKSKKLHQLEVPILMLEACQTYYINLPSRVTQRMICAGFPLEEGKDSCTGDSGGPLVCPSEDGSGFYTLHGITSWGLGCGRKSYPGVYTNVGVFVDWIKQSINSSDLPIFMV", "length": 863, "header": "tr|A0A8V0ZIX6-1|A0A8V0ZIX6_CHICK Isoform 1 of Ovochymase 1 OS=Gallus gallus OX=9031 GN=OVCH2 PE=1 SV=1 CANONICAL=A0A8V0ZIX6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX6/entry#A0A8V0ZIX6-1", "sequence": { "sequence": "MCITSSKLLLLLLGVVCITESRAVPHILQKDPKCGQKVHETKPWSYFNLFTRIVGGNQVKQGSHPWQVSLKRREKHFCGGTIVSAQWVVTAAHCVSDRADSTHFDCTYYTRKSEDERNLLKYLNVTAGEHDLRIRENGEQTLPVKYIIKHPNFDPRRPMNYDIALLKLDGTFNFSSSVLPACLPDPGEKFEAGYICTACGWGRLRENGVLPQVLYEVNLPILNSMECSRALSTLRKPIQGDTILCAGFPDGGKDACQGDSGGPLLCRRKHGAWILAGVISWGMGCARGWRGNEMKRHYERGSPGIFTDLSAVLSWIQENMSADLKMKSSTPFCSVQDGKLTDSEGELNFPGGSEQFYQNHQLCIWTLFVPEGNYILLHFSHFDIEPETFCDYDSLSVYSKDDRLVGKFCGGDLPLPILIGSNNIRLKFVSDNKDYGTGFSMTYKALTTGILPDSGCESLAVLFEEGVLQSMHYPENYSNLAVCQWIICAPEDHVIKLTYQTFEVEESEDCSYDAVTVYEDAGKEEEIAKSCGFVLPAPVLSSSSMMLVVFHSDETETFEGFRATITFVHVTDLDTLDSASVEVFENTDMTEEEIQVTTDDVCGMPSNQPRFIFSRIIGGEEAVPHSWPWQVSIQISDQHICGGAVLAKEWVITAAHCFNSKELYRDLWMVVTGIHDLTEQEYRQKRSVKQYIIHPSFNKTTMDSDIALLQLAEPLEFNHYVHPVCLPAKEEVVQPSSVCIITGWGAQEEDREKSKKLHQLEVPILMLEACQTYYINLPSRVTQRMICAGFPLEEGKDSCTGDSGGPLVCPSEDGSGFYTLHGITSWGLGCGRKSYPGVYTNVGVFVDWIKQSINSSDLPIFMV", "length": 863, "header": "tr|A0A8V0ZIX6-1|A0A8V0ZIX6_CHICK Isoform 1 of Ovochymase 1 OS=Gallus gallus OX=9031 GN=OVCH2 PE=1 SV=1 CANONICAL=A0A8V0ZIX6-1" }, "locus": { "chromosome": "5", "start_pos": 7105474, "end_pos": 7090106, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052393.1", "url": "https://www.ensembl.org/id/ENSGALT00010052393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031311.1", "url": "https://www.ensembl.org/id/ENSGALP00010031311.1" } ] } }, { "isoform_ac": "A0A8V0ZRB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX6/entry#A0A8V0ZRB2-1", "sequence": { "sequence": "MCITSSKLLLLLLGVVCITESRAVPHILQKDPKCGQKVHETKPWSYFNLFTRIVGGNQVKQGSHPWQVSLKRREKHFCGGTIVSAQWVVTAAHCVSDRNLLKYLNVTAGEHDLRIRENGEQTLPVKYIIKHPNFDPRRPMNYDIALLKLDGTFNFSSSVLPACLPDPGEKFEAGYICTACGWGRLRENGVLPQVLYEVNLPILNSMECSRALSTLRKPIQGDTILCAGFPDGGKDACQGDSGGPLLCRRKHGAWILAGVISWGMGCARGWRGNEMKRHYERGSPGIFTDLSAVLSWIQENMSADLKMKSSTPFCSVQDGKLTDSEGELNFPGGSEQFYQNHQLCIWTLFVPEGNYILLHFSHFDIEPETFCDYDSLSVYSKDDRLVGKFCGGDLPLPILIGSNNIRLKFVSDNKDYGTGFSMTYKALTTGILPDSGCESLAVLFEEGVLQSMHYPENYSNLAVCQWIICAPEDHVIKLTYQTFEVEESEDCSYDAVTVYEDAGKEEEIAKSCGFVLPAPVLSSSSMMLVVFHSDETETFEGFRATITFVHVTDLDTLDSASVEVFENTDMTEEEIQVTTDDVCGMPSNQPRFIFSRIIGGEEAVPHSWPWQVSIQISDQHICGGAVLAKEWVITAAHCFNSKELYRDLWMVVTGIHDLTEQEYRQKRSVKQYIIHPSFNKTTMDSDIALLQLAEPLEFNHYVHPVCLPAKEEVVQPSSVCIITGWGAQEEDREKSKKLHQLEVPILMLEACQTYYINLPSRVTQRMICAGFPLEEGKDSCTGDSGGPLVCPSEDGSGFYTLHGITSWGLGCGRKSYPGVYTNVGVFVDWIKQSINSSGMYGSKPKQLSKSFGYC", "length": 854, "header": "tr|A0A8V0ZRB2-1|A0A8V0ZRB2_CHICK Computationally mapped isoform of Ovochymase 1 OS=Gallus gallus OX=9031 GN=OVCH2 PE=1 SV=1 CANONICAL=A0A8V0ZIX6-1" }, "locus": { "chromosome": "5", "start_pos": 7105474, "end_pos": 7090526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052385.1", "url": "https://www.ensembl.org/id/ENSGALT00010052385.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031305.1", "url": "https://www.ensembl.org/id/ENSGALP00010031305.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIX6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": 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genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5NVU8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NVU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PMC0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PMC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAAHTSHSASSGEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLQQICLCGYYENLEKGITLFRQGDIGSNWYAVLTGSLDVKVSDTSNHQDAVTICTLGIGTAFGESILDNTPRHATIVTREYSELLRIEQKDFKALWEKYRQYMSGLLTPPYGVMETGSNNDRMPDKDSMSSGALCQVSKNCNKVPSEKILRAGKILRNTILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQSTCVHSRSQAVGMWQVLLEEGVLNHVDQEHHFQDKYLFYRFLDDEREDAPLPTEEEKKECDEELQDTMLLLSQIGPDAHMRMILRKPPGQRSIDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHPKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKIPAGNRVSNQGSSQPQHKYIVMSGTPEKILEHFLETMRLEATLNEATDSVLNDFIMMHCVFMPNSQLCPALMAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAALYGDLLQEDEAAMAFLEEFYVSVSDDTRMIAALKEQLPELEKIVKQVAEEPKAPQKKHKVLLQLFNTSDDRAQKRQPIRGSDEVLFKVYCIDQTYTTIRVPVSSSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPHDVSVFTTLSVNGRLFACPRDQFDSLAPLPEQEGPSAGTVGTFELMSSKDLAHQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKYIKIAAHCKEYKNLNSFFAIIMGLSNVAVSRLSLTWEKLPSKFKKIYAEFESLMDPSRNHRAYRLTVAKLDPPIIPFMPLLIKDMTFTHEGNKTLTDNLVNFEKMRMIANTVRTVKFCRSQSFNPDAALANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRA", "length": 1008, "header": "tr|A0A8V0ZKI7-1|A0A8V0ZKI7_CHICK Isoform 1 of Rap guanine nucleotide exchange factor 4 OS=Gallus gallus OX=9031 GN=RAPGEF4 PE=4 SV=1 CANONICAL=A0A8V0ZKI7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NVU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7/entry#A0A1D5NVU8-1", "sequence": { "sequence": "MVAAHTSHSASSGEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLQQICLCGYYENLEKGITLFRQGDIGSNWYAVLTGSLDVKVSDTSNHQKYRQYMSGLLTPPYGVMETGSNNDRMPDKDSMSSGALCQVSKNCNKTPLIDSHIPHRPSKTITQVPSEKILRAGKILRNTILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQSTCVHSRSQAVGMWQVLLEEGVLNHVDQEHHFQDKYLFYRFLDDEREDAPLPTEEEKKECDEELQDTMLLLSQIGPDAHMRMILRKPPGQRSIDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHPKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKIPAGNRVSNQGSSQPQHKYIVMSGTPEKILEHFLETMRLEATLNEATDSVLNDFIMMHCVFMPNSQLCPALMAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAALYGDLLQEDEAAMAFLEEFYVSVSDDTRMIAALKEQLPELEKIVKQVAEEPKAPQKKHKVLLQLFNTSDDRAQKRQPIRGSDEVLFKVYCIDQTYTTIRVPVSSSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPHDVSVFTTLSVNGRLFACPRDQFDSLAPLPEQEGPSAGTVGTFELMSSKDLAHQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKYIKIAAHCKEYKNLNSFFAIIMGLSNVAVSRLSLTWEKLPSKFKKIYAEFESLMDPSRNHRAYRLTVAKLDPPIIPFMPLLIKDMTFTHEGNKTLTDNLVNFEKMRMIANTVRTVKFCRSQSFNPDAALANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRA", "length": 977, "header": "tr|A0A1D5NVU8-1|A0A8V0ZKI7_CHICK Computationally mapped isoform of Rap guanine nucleotide exchange factor 4 OS=Gallus gallus OX=9031 GN=RAPGEF4 PE=4 SV=2 CANONICAL=A0A8V0ZKI7-1" }, "locus": { "chromosome": "7", "start_pos": 17207723, "end_pos": 17064283, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052996.1", "url": "https://www.ensembl.org/id/ENSGALT00010052996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031902.1", "url": "https://www.ensembl.org/id/ENSGALP00010031902.1" } ] } }, { "isoform_ac": "A0A1D5PMC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7/entry#A0A1D5PMC0-1", "sequence": { "sequence": "MVAAHTSHSASSGEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLQQICLCGYYENLEKGITLFRQGDIGSNWYAVLTGSLDVKVSDTSNHQDAVTICTLGIGTAFGESILDNTPRHATIVTREYSELLRIEQKDFKALWEKYRQYMSGLLTPPYGVMETGSNNDRMPDKDSMSSGALCQVSKNCNKTPLIDSHIPHRPSKTITQVPSEKILRAGKILRNTILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQSTCVHSRSQAVGMWQVLLEEGVLNHVDQEHHFQDKYLFYRFLDDEREDAPLPTEEEKKECDEELQDTMLLLSQIGPDAHMRMILRKPPGQRSIDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHPKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKIPAGNRVSNQGSSQPQHKYIVMSGTPEKILEHFLETMRLEATLNEATDSVLNDFIMMHCVFMPNSQLCPALMAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAALYGDLLQEDEAAMAFLEEFYVSVSDDTRMIAALKEQLPELEKIVKQVAEEPKAPQKKHKVLLQLFNTSDDRAQKRQPIRGSDEVLFKVYCIDQTYTTIRVPVSSSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPHDVSVFTTLSVNGRLFACPRDQFDSLAPLPEQEGPSAGTVGTFELMSSKDLAHQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKYIKIAAHCKEYKNLNSFFAIIMGLSNVAVSRLSLTWEKLPSKFKKIYAEFESLMDPSRNHRAYRLTVAKLDPPIIPFMPLLIKDMTFTHEGNKTLTDNLVNFEKMRMIANTVRTVKFCRSQSFNPDAALANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRA", "length": 1026, "header": "tr|A0A1D5PMC0-1|A0A8V0ZKI7_CHICK Computationally mapped isoform of Rap guanine nucleotide exchange factor 4 OS=Gallus gallus OX=9031 GN=RAPGEF4 PE=4 SV=2 CANONICAL=A0A8V0ZKI7-1" }, "locus": { "chromosome": "7", "start_pos": 17207723, "end_pos": 17064283, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052988.1", "url": "https://www.ensembl.org/id/ENSGALT00010052988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031894.1", "url": "https://www.ensembl.org/id/ENSGALP00010031894.1" } ] } }, { "isoform_ac": "A0A8V0ZF43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7/entry#A0A8V0ZF43-1", "sequence": { "sequence": "MLPLLPENIASSFELSRRTSKHFGRNTGSICLDFLLLLMVLWKLAPTMTECQIRTVCQAVLFAKFLKIVIRQCCVGTELVDWMMQQSTCVHSRSQAVGMWQVLLEEGVLNHVDQEHHFQDKYLFYRFLDDEREDAPLPTEEEKKECDEELQDTMLLLSQIGPDAHMRMILRKPPGQRSIDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHPKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKIPAGNRVSNQGSSQPQHKYIVMSGTPEKILEHFLETMRLEATLNEATDSVLNDFIMMHCVFMPNSQLCPALMAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAALYGDLLQEDEAAMAFLEEFYVSVSDDTRMIAALKEQLPELEKIVKQVAEEPKAPQKKHKVLLQLFNTSDDRAQKRQPIRGSDEVLFKVYCIDQTYTTIRVPVSSSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPHDVSVFTTLSVNGRLFACPRDQFDSLAPLPEQEGPSAGTVGTFELMSSKDLAHQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKYIKIAAHCKEYKNLNSFFAIIMGLSNVAVSRLSLTWEKLPSKFKKIYAEFESLMDPSRNHRAYRLTVAKLDPPIIPFMPLLIKDMTFTHEGNKTLTDNLVNFEKMRMIANTVRTVKFCRSQSFNPDAALANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRA", "length": 849, "header": "tr|A0A8V0ZF43-1|A0A8V0ZKI7_CHICK Computationally mapped isoform of Rap guanine nucleotide exchange factor 4 OS=Gallus gallus OX=9031 GN=RAPGEF4 PE=4 SV=1 CANONICAL=A0A8V0ZKI7-1" }, "locus": { "chromosome": "7", "start_pos": 17187277, "end_pos": 17064283, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053009.1", "url": "https://www.ensembl.org/id/ENSGALT00010053009.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031915.1", "url": "https://www.ensembl.org/id/ENSGALP00010031915.1" } ] } }, { "isoform_ac": "A0A8V0ZKI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7/entry#A0A8V0ZKI7-1", "sequence": { "sequence": "MVAAHTSHSASSGEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLQQICLCGYYENLEKGITLFRQGDIGSNWYAVLTGSLDVKVSDTSNHQDAVTICTLGIGTAFGESILDNTPRHATIVTREYSELLRIEQKDFKALWEKYRQYMSGLLTPPYGVMETGSNNDRMPDKDSMSSGALCQVSKNCNKVPSEKILRAGKILRNTILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQSTCVHSRSQAVGMWQVLLEEGVLNHVDQEHHFQDKYLFYRFLDDEREDAPLPTEEEKKECDEELQDTMLLLSQIGPDAHMRMILRKPPGQRSIDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHPKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKIPAGNRVSNQGSSQPQHKYIVMSGTPEKILEHFLETMRLEATLNEATDSVLNDFIMMHCVFMPNSQLCPALMAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAALYGDLLQEDEAAMAFLEEFYVSVSDDTRMIAALKEQLPELEKIVKQVAEEPKAPQKKHKVLLQLFNTSDDRAQKRQPIRGSDEVLFKVYCIDQTYTTIRVPVSSSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPHDVSVFTTLSVNGRLFACPRDQFDSLAPLPEQEGPSAGTVGTFELMSSKDLAHQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKYIKIAAHCKEYKNLNSFFAIIMGLSNVAVSRLSLTWEKLPSKFKKIYAEFESLMDPSRNHRAYRLTVAKLDPPIIPFMPLLIKDMTFTHEGNKTLTDNLVNFEKMRMIANTVRTVKFCRSQSFNPDAALANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRA", "length": 1008, "header": "tr|A0A8V0ZKI7-1|A0A8V0ZKI7_CHICK Isoform 1 of Rap guanine nucleotide exchange factor 4 OS=Gallus gallus OX=9031 GN=RAPGEF4 PE=4 SV=1 CANONICAL=A0A8V0ZKI7-1" }, "locus": { "chromosome": "7", "start_pos": 17207723, "end_pos": 17064283, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053000.1", "url": "https://www.ensembl.org/id/ENSGALT00010053000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031906.1", "url": "https://www.ensembl.org/id/ENSGALP00010031906.1" } ] } }, { "isoform_ac": "A0A8V0ZM50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7/entry#A0A8V0ZM50-1", "sequence": { "sequence": "MWVWFVFQGSITLPGVADAVTICTLGIGTAFGESILDNTPRHATIVTREYSELLRIEQKDFKALWEKYRQYMSGLLTPPYGVMETGSNNDRMPDKDSMSSGALCQVSKNCNKTPLIDSHIPHRPSKTITQVPSEKILRAGKILRNTILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQSTCVHSRSQAVGMWQVLLEEGVLNHVDQEHHFQDKYLFYRFLDDEREDAPLPTEEEKKECDEELQDTMLLLSQIGPDAHMRMILRKPPGQRSIDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHPKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKIPAGNRVSNQGSSQPQHKYIVMSGTPEKILEHFLETMRLEATLNEATDSVLNDFIMMHCVFMPNSQLCPALMAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAALYGDLLQEDEAAMAFLEEFYVSVSDDTRMIAALKEQLPELEKIVKQVAEEPKAPQKKHKVLLQLFNTSDDRAQKRQPIRGSDEVLFKVYCIDQTYTTIRVPVSSSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPHDVSVFTTLSVNGRLFACPRDQFDSLAPLPEQEGPSAGTVGTFELMSSKDLAHQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKYIKIAAHCKEYKNLNSFFAIIMGLSNVAVSRLSLTWEKLPSKFKKIYAEFESLMDPSRNHRAYRLTVAKLDPPIIPFMPLLIKDMTFTHEGNKTLTDNLVNFEKMRMIANTVRTVKFCRSQSFNPDAALANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRA", "length": 944, "header": "tr|A0A8V0ZM50-1|A0A8V0ZM50_CHICK Computationally mapped isoform of Rap guanine nucleotide exchange factor 4 OS=Gallus gallus OX=9031 GN=RAPGEF4 PE=4 SV=1 CANONICAL=A0A8V0ZKI7-1" }, "locus": { "chromosome": "7", "start_pos": 17192399, "end_pos": 17064283, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052982.1", "url": "https://www.ensembl.org/id/ENSGALT00010052982.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031888.1", "url": "https://www.ensembl.org/id/ENSGALP00010031888.1" } ] } }, { "isoform_ac": "A0A8V0ZMF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7/entry#A0A8V0ZMF3-1", "sequence": { "sequence": "MVLWKLAPTMTECQIRTVCQAVLFAKFLKIVIRQCCVGTELVDWMMQQSTCVHSRSQAVGMWQVLLEEGVLNHVDQEHHFQDKYLFYRFLDDEREDAPLPTEEEKKECDEELQDTMLLLSQIGPDAHMRMILRKPPGQRSIDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHPKAGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKIPAGNRVSNQGSSQPQHKYIVMSGTPEKILEHFLETMRLEATLNEATDSVLNDFIMMHCVFMPNSQLCPALMAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAALYGDLLQEDEAAMAFLEEFYVSVSDDTRMIAALKEQLPELEKIVKQVAEEPKAPQKKHKVLLQLFNTSDDRAQKRQPIRGSDEVLFKVYCIDQTYTTIRVPVSSSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPHDVSVFTTLSVNGRLFACPRDQFDSLAPLPEQEGPSAGTVGTFELMSSKDLAHQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKYIKIAAHCKEYKNLNSFFAIIMGLSNVAVSRLSLTWEKLPSKFKKIYAEFESLMDPSRNHRAYRLTVAKLDPPIIPFMPLLIKDMTFTHEGNKTLTDNLVNFEKMRMIANTVRTVKFCRSQSFNPDAALANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRA", "length": 811, "header": "tr|A0A8V0ZMF3-1|A0A8V0ZMF3_CHICK Computationally mapped isoform of Rap guanine nucleotide exchange factor 4 OS=Gallus gallus OX=9031 GN=RAPGEF4 PE=4 SV=1 CANONICAL=A0A8V0ZKI7-1" }, "locus": { "chromosome": "7", "start_pos": 17140261, "end_pos": 17064283, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052976.1", "url": "https://www.ensembl.org/id/ENSGALT00010052976.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031882.1", "url": "https://www.ensembl.org/id/ENSGALP00010031882.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-354192", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-354192", "resource": "Reactome", "description": "Integrin signaling" }, { "id": "R-GGA-381676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381676", "resource": "Reactome", "description": "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" }, { "id": "R-GGA-392517", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-392517", "resource": "Reactome", "description": "Rap1 signalling" }, { "id": "R-GGA-422356", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-422356", "resource": "Reactome", "description": "Regulation of insulin secretion" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SGQ1-1", "protein_name": "Rap guanine nucleotide exchange factor 4", "gene_name": "RAPGEF4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPCKKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMLQQTPCVHSRTQAVGMWQVLVEDSVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMVLRKPPGQRTMDDLEIIYEELLHIKALSHLSTTVKRELAAVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEPALNEATDSVLNDFVMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDILQEDDVAMAFLEEFYVSVSDDARMLAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCVDHTYTTIRVPVAASVKEVLSAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTMGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHHFKKTTANLDLFLRRFNEIQFWVVTEICLCSQPSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLDPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYCRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP", "length": 867 }, "evidence": [ { "id": "A0A8V0ZKI7", "url": "https://omabrowser.org/oma/group/A0A8V0ZKI7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A1Z6P8-1", "protein_name": "Exchange protein directly activated by cAMP, isoform E", "gene_name": "Epac", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAMEWITAMDKRPCDRNLRDVELISCRLRRVEPLCRLPGSALQQLAMCGFYEDLEKGVTLFRAGEQGRFWYAVLGGSLEVRYHAHADADGKSAVTLCNLGVGATFGESVLHDLPRDSTVVTKTTCELLRVEQQDFRLIWEKNKELMNDIFTNCKLKNGFGPSVQATAAATSPTKRPLSPDHPNPALPITETPSPAMNRMGWALRTLLVADNSSCLKDRKVSGKLIRKCAPGTELVDWLVNLSPIVHTRAQAAGMWQALLEEGVLAHVNKEQPFKDKCFLYRFRIDEEGGTAAAGVPQAEDLGAANEHIREALSALFQRGPDATLRMILRKPSHERTSEELELVFEELVHIAALSHLSTSIKRELSSIFVFEAHAQAGTILFNQGDEGRSWYILLKGSVDVVIHGKGTVATLKTGDDFGKLALINDAPRAATIVLKENNCHLLRVDKEHFNRILRDVEANTLRLQEHGKDVLVLERVAKQRGQHSAFKYTVMSGTPAKMLEHLLETRLGQSVGGMDPFLDDFLLTHIVFMPVVQLVDELANYFHCDAHEDAQTPEDREYIINFKKRVIQFMQKWVMAVRHAAFEEPSVCDFIEDLAAEVEADPDLNEETSIVHNVLTQMARYQEDRNQNAGQKWKLPPNGQPICLFSGNATPSKTVIRPDDDIIFRVYCADHTYCTLRFPMHTTAELIKACAADKLQLNRGPEDLVLVEVKSNGERSVFKDNDVSIPTGLSLNGRLFVSVKDHLDALTQLQEQECPTEGVDIDLEILSTKELAYHITLFEWDLFWAVHEYELLYHTFGRHHFGKITANLDVFLRRFNEVQYWIVTELVSTPSLSKRVGLVRKFIKLAAYCKEYQNLNAFFAVVMGLSNMAVSRLQQTWEKIPSKFRKIFQEFEALIDPSRNHRAYRVFVGKLQPPLIPFMPLLLKDMTFAHEGNKTSLDGLVNFEKMHMMAQTMRTIRFCRSRSLGLEPPSPKSEGEVRSYISSFRVIDNQRVLTAMSQKVEPTRKL", "length": 1006 }, "evidence": [ { "id": "A0A8V0ZKI7", "url": "https://omabrowser.org/oma/group/A0A8V0ZKI7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8WZA2-1", "protein_name": "Rap guanine nucleotide exchange factor 4", "gene_name": "RAPGEF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVAAHAAHSSSSAEWIACLDKRPLERSSEDVDIIFTRLKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQKDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPANTITKVPSEKILRAGKILRNAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHFQDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEATLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVADKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP", "length": 1011 }, "evidence": [ { "id": "A0A8V0ZKI7", "url": "https://omabrowser.org/oma/group/A0A8V0ZKI7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQZ6-1", "protein_name": "Rap guanine nucleotide exchange factor 4", "gene_name": "Rapgef4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVAAHAAHSQSSAEWIACLDKRPLERSSEDVDIIFTRLKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTLGIGTAFGESILDNTPRHATIVTRESSELLRIEQEDFKALWEKYRQYMAGLLAPPYGVMETGSNNDRIPDKENTPLIEPHVPLRPAHTITKVPSEKILRAGKILRIAILSRAPHMIRDRKYHLKTYRQCCVGTELVDWMIQQTSCVHSRTQAVGMWQVLLEDGVLNHVDQERHFQDKYLFYRFLDDEREDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVPAGNRAANQGNSQPQQKYTVMSGTPEKILEHFLETIRLEPSLNEATDSVLNDFVMMHCVFMPNTQLCPALVAHYHAQPSQGTEQERMDYALNNKRRVIRLVLQWAAMYGDLLQEDDVAMAFLEEFYVSVSDDARMMAAFKEQLPELEKIVKQISEDAKAPQKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCIDHTYTTIRVPVAASVKEVISAVADKLGSGEGLIIVKMNSGGEKVVLKSNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGPTTGTVGTFELMSSKDLAYQMTTYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRFNEIQFWVVTEVCLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLALTWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTAAKLEPPLIPFMPLLIKDMTFTHEGNKTFIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLSQMSHRLEPRRP", "length": 1011 }, "evidence": [ { "id": "A0A8V0ZKI7", "url": "https://omabrowser.org/oma/group/A0A8V0ZKI7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" }, { "name": "regulation of insulin secretion", "id": "GO:0050796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050796", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" }, { "name": "Rap protein signal transduction", "id": "GO:0032486", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032486", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle cycle", "id": "GO:0098693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" }, { "name": "cAMP binding", "id": "GO:0030552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" }, { "start_pos": 935, "end_pos": 937, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" }, { "id": "PS50042", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50042" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclic nucleotide-binding", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 146, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZKI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKI7" }, { "id": "PS50186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50186" } ], "ann_type": "Domain_Extent_Annotation", 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[], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 649, "end_pos": 651 }, { "start_pos": 935, "end_pos": 937 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZM03-1", "uniprot_ac": "A0A8V0ZM03", "uniprot_id": "A0A8V0ZM03_CHICK", "mass": { "chemical_mass": 166705.0, "monoisotopic_mass": 166705.0 }, "refseq": { "ac": "XP_015151731", "name": "ral GTPase-activating protein subunit beta isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151731" }, "gene_names": [ { "name": "RALGAPB", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03" } ] }, { "name": "RALGAPB", "type": "synonym", "evidence": [ { "id": "XP_015151731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151731" } ] } ], "protein_names": [ { "name": "Ral GTPase-activating protein subunit beta", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03/entry#names_and_taxonomy" } ] }, { "name": "p170", "type": "synonym", "evidence": [ { "id": "A0A8V0ZM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03/entry#names_and_taxonomy" } ] }, { "name": "ral GTPase-activating protein subunit beta isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015151731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151731" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015151731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151731" } ] }, { "annotation": "Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators for the Ras-like small GTPases RALA and RALB.", "evidence": [ { "database": "UniProtKB", "id": "R4GK99", "url": "https://www.uniprot.org/uniprotkb/R4GK99#function" }, { "database": "UniProtKB", "id": "ARBA00053327", "url": "https://www.uniprot.org/uniprotkb/ARBA00053327#function" }, { "database": "UniProtKB", "id": "A0A8V0ZM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RALGAPB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03", "locus": { "chromosome": "20", "start_pos": 1074432, "end_pos": 1139599, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021770", "url": "https://www.ensembl.org/id/ENSGALG00010021770" } ] } } ], "crossref": [ { "id": "ENSGALG00000001420", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001420", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "419128", "url": "https://www.ncbi.nlm.nih.gov/gene/419128", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CWEECCV", "url": "https://omabrowser.org/oma/group/CWEECCV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM03", "url": "https://www.orthodb.org/?gene=A0A8V0ZM03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GK99", "url": "https://www.orthodb.org/?gene=R4GK99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21344:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21344:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015151731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015151731", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GK99", "url": "https://www.uniprot.org/uniprotkb/R4GK99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GK99-1", "url": "https://www.uniprot.org/uniprotkb/R4GK99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYSEWRSLHLVIQNDQGNTSVLHSYPESVGREVANAVVRPLGQALITSSVGSESLLKTDKEVKWTMEVVCYGLTLPLDGDTVKYCVDVYTDWIMALVLPKDSIPLPVIKEPNLYVQSILKHLQNLFVPRPDPGSSQIRLCLQVLKAVQKLARESTIMARETWEVLLLFLLQINDTLLAAPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKIPEEDAGLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMTQELNQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQNTAINTTPPHNRRHRAVTVNKATMKTSTVTTAHASKVQHQPSSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTAIATQASVEFRRKGSQMSTDTMASNPLFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQIADFVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKIYVNPTELRRASINILLSLLPLPHHFGTVKSEVVLEGKFSNDDSSTYDKPVTFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMETNGGENNLFKSHSRTNSGISTASGGSTEPTTPDSERPAQALLRDYALNTDTAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVLVDSSDQKRAISSVCSYIVFQCSRPAPLHSRDLHSVIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKSSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDSFPSVTVLIRGTSGRFAWAQQLCLLPRGAKANQKTFVPEPRPAPKNDVGLKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVNEELEERHEKLRNGMAQQIIFETSIDQRSEEEWRKKSFPDPITECKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTLPGFFDDLGYLDLLPCRPFDTVFIFYMKAGQKTSQEILKNMESSRIVQPHFLEFLLSLGWSVDVGKHPGWTGHVSTSWSINSCSDEEGPEQDDVIISEDVGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNVSDQESDSNMDLLPGILKQPSLTLELFPNHTDNLNPSQRLSPTSRSKRVPQGRTIPPMGPETKVYVVWVERYDDIENFPLPDLVSETSTGVETTANSSTSLRSTIPEKEVPVIFIHPLNTGLFRIKLQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYNPPHVRRKQKIADIVNKYRNRQLEPEFYTSLFQEVGLKNCNP", "length": 1495, "header": "tr|A0A8V0ZM03-1|A0A8V0ZM03_CHICK Isoform 1 of Ral GTPase-activating protein subunit beta OS=Gallus gallus OX=9031 GN=RALGAPB PE=1 SV=1 CANONICAL=A0A8V0ZM03-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZM03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03/entry#A0A8V0ZM03-1", "sequence": { "sequence": "MYSEWRSLHLVIQNDQGNTSVLHSYPESVGREVANAVVRPLGQALITSSVGSESLLKTDKEVKWTMEVVCYGLTLPLDGDTVKYCVDVYTDWIMALVLPKDSIPLPVIKEPNLYVQSILKHLQNLFVPRPDPGSSQIRLCLQVLKAVQKLARESTIMARETWEVLLLFLLQINDTLLAAPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKIPEEDAGLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMTQELNQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQNTAINTTPPHNRRHRAVTVNKATMKTSTVTTAHASKVQHQPSSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTAIATQASVEFRRKGSQMSTDTMASNPLFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQIADFVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKIYVNPTELRRASINILLSLLPLPHHFGTVKSEVVLEGKFSNDDSSTYDKPVTFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMETNGGENNLFKSHSRTNSGISTASGGSTEPTTPDSERPAQALLRDYALNTDTAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVLVDSSDQKRAISSVCSYIVFQCSRPAPLHSRDLHSVIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKSSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDSFPSVTVLIRGTSGRFAWAQQLCLLPRGAKANQKTFVPEPRPAPKNDVGLKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVNEELEERHEKLRNGMAQQIIFETSIDQRSEEEWRKKSFPDPITECKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTLPGFFDDLGYLDLLPCRPFDTVFIFYMKAGQKTSQEILKNMESSRIVQPHFLEFLLSLGWSVDVGKHPGWTGHVSTSWSINSCSDEEGPEQDDVIISEDVGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNVSDQESDSNMDLLPGILKQPSLTLELFPNHTDNLNPSQRLSPTSRSKRVPQGRTIPPMGPETKVYVVWVERYDDIENFPLPDLVSETSTGVETTANSSTSLRSTIPEKEVPVIFIHPLNTGLFRIKLQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYNPPHVRRKQKIADIVNKYRNRQLEPEFYTSLFQEVGLKNCNP", "length": 1495, "header": "tr|A0A8V0ZM03-1|A0A8V0ZM03_CHICK Isoform 1 of Ral GTPase-activating protein subunit beta OS=Gallus gallus OX=9031 GN=RALGAPB PE=1 SV=1 CANONICAL=A0A8V0ZM03-1" }, "locus": { "chromosome": "20", "start_pos": 1134004, "end_pos": 1078176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052936.1", "url": "https://www.ensembl.org/id/ENSGALT00010052936.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031842.1", "url": "https://www.ensembl.org/id/ENSGALP00010031842.1" } ] } }, { "isoform_ac": "R4GK99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03/entry#R4GK99-1", "sequence": { "sequence": "MYSEWRSLHLVIQNDQGNTSVLHSYPESVGREVANAVVRPLGQALITSSVGSESLLKTDKEVKWTMEVVCYGLTLPLDGDTVKYCVDVYTDWIMALVLPKDSIPLPVIKEPNLYVQSILKHLQNLFVPRPDPGSSQIRLCLQVLKAVQKLARESTIMARETWEVLLLFLLQINDTLLAAPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKIPEEDAGLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMTQELNQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQNTAINTTPPHNRRHRAVTVNKATMKTSTVTTAHASKVQHQPSSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTASFIQILLSYKSSIATQASVEFRRKGSQMSTDTMASNPLFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQIADFVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKIYVNPTELRRASINILLSLLPLPHHFGTVKSEVVLEGKFSNDDSSTYDKPVTFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMETNGGENNLFKSHSRTNSGISTASGGSTEPTTPDSERPAQALLRDYALNTDTAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVLVDSSDQKRAISSVCSYIVFQCSRPAPLHSRDLHSVIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKSSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDSFPSVTVLIRGTSGRFAWAQQLCLLPRGAKANQKTFVPEPRPAPKNDVGLKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVNEELEERHEKLRNGMAQQIIFETSIDQRSEEEWRKKSFPDPITECKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTLPGFFDDLGYLDLLPCRPFDTVFIFYMKAGQKTSQEILKNMESSRIVQPHFLEFLLSLGWSVDVGKHPGWTGHVSTSWSINSCSDEEGPEQDDVIISEDVGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNVSDQESDSNMDLLPGILKQPSLTLELFPNHTDNLNPSQRLSPTSRSKRVPQGRTIPPMGPETKVYVVWVERYDDIENFPLPDLVSETSTGVETTANSSTSLRSTIPEKEVPVIFIHPLNTGLFRIKLQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYNPPHVRRKQKIADIVNKYRNRQLEPEFYTSLFQEVGLKNCNP", "length": 1507, "header": "tr|R4GK99-1|A0A8V0ZM03_CHICK Computationally mapped isoform of Ral GTPase-activating protein subunit beta OS=Gallus gallus OX=9031 GN=RALGAPB PE=1 SV=1 CANONICAL=A0A8V0ZM03-1" }, "locus": { "chromosome": "20", "start_pos": 1134004, "end_pos": 1078176, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052932.1", "url": "https://www.ensembl.org/id/ENSGALT00010052932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031838.1", "url": "https://www.ensembl.org/id/ENSGALP00010031838.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 212, "start_aa": "Thr", "end_pos": 212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr212", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 362, "start_aa": "Thr", "end_pos": 362, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr362", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3ATR5-1", "protein_name": "Ral GTPase-activating protein subunit beta", "gene_name": "ralgapb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYSEWRSLHLVVQSDQGHLSVLHTYPAGVGRDVANAVVRPLGNSLGGVPSECLLKTDKEVKWTMEVLCYGLTLPLDGDTVKLCVDVYTDWIMALVSPRDSIPQPIIKEPDLYVQTILKHLHNLFLPRPENFSLVHFKLCQQVLSAVQKLARDSSSMARETWEVLLLFLLRINDTLLAPPTVGGGLAEKLAEKLISVLFEVWFLACTRCFPTPPYWKTAREMLANWRHHPPVVEQWSKVIAALTSRLLRFMYGPSFPPFKVPEEDASLIPAEMDNDCVAQTWYRFLHMLSNPVDLSNPVIVSSTPKFQEQLLGVNSVPHEVIQHPCLKQLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPPPPTTTNTTPPHNRRHRPTAVAKTTSKSSTTGQTRVSHQPSSTSPLSSPNQTSSEPRPLPAPTRPKVNSVLNLFGQWLFDAALVHCKLHSGLSRDSSMTALATQAGVELRRKGSQMSTDTMVSNPMFDANEFPDNYESGRAEACGTLCRIFCSKKTGEEILPVYLSRFYMVLIQGLQISDFICRPVLASIILNSSALFCSDLKGINVVVPYFISALETILPDRELSKFKSYVNPTELRRASIHILLSMLPLPHHFGNVKSEVLLEGKFSNDDNSLHDKAVTFLSLKLRLVNILIGALQTETDPINTQMILAAMLNIVQDSALLESVGAQAEVGSVDGSHSLAKSHSRNNSGISNASAGSSEATTPDSERPAQALLRDYDTAAGLLIRSIHLLTQRLNSQWRLDMSISLAALELLAGLAKVKVSVESSDRKRAVSSVCSYIVYQCSRPAPLHSRDLHSMIVAAFHCLCVWLTEHPDMLNEKDCLIEVLEIVELGISGSKSKTGEQEVKYKGDKEHNPASMRVKDAAEATLSCIMQVLGAFPSPSGPASPCSLLNEDTLIKYSRLTSTSHSNFRYFVLDNSVILAMLEQPLGNEQNPCPSVTMLIRGMSGRHAWTMQLFHQPRGARANQKQVFVPESRPTPKNDVGIRFNVKHRPFPEEVDKIPFVKADLSIPDLHDIVDKELEQQHDKLRVVMGKQIDYETKLEHHTEDLWRNKAFPDPLTDCKPPAPAQEFQTARLFLSHFGFLSLEALKEPGNSRLPPHLIALDSSVPGFFDDVGYLDLLPSRPCDTVFIFYMRAGQKSSQEILKNVESSANVQPHFLELLLSLGWPVEVAQHPGWTGSVFTSWTINTSNGADTPDDSVTLGDTGGGVFNGEKQVLYYADALTEIAFVVPSLSDSSAESSEHSFPTADSDSQMELLPSLLKQPNLTLELFPNHSDNMGPAQRSPTAKNKKLPPGRTIPPLGPDTKVLVVWVERYDDIENFPVSELLAETSTGVETAVNSSASRSSSSEKDVPIVFIHPLKTGLFRIKLQGALGKFNMVIPLVDNMVVSRRSLGFLVRQTVINACRRKRLESDSYSPPHVRRKQKIAEIVNRYRNKQLEPEFYTSLFLEVNETSLKP", "length": 1486 }, "evidence": [ { "id": "A0A8V0ZM03", "url": "https://omabrowser.org/oma/group/A0A8V0ZM03/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LRQ6-1", "protein_name": "Ral GTPase-activating protein subunit beta", "gene_name": "RALGAPB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYSEWRSLHLVIQNDQGHTSVLHSYPESVGREVANAVVHPLGQALGTPSVAGSESLLKTDKEVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKDSIPLPIIKEPNLYVQSILKHLQNLFVPRQDQGSGQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACARCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDASLIPPEMDNECVAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMPQELNQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSTAVNTTPPHNRRHRAVTVNKATMKTSTVTTAHASKVQHQTSSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTAITTQASMEFRRKGSQMSTDTMVSNPMFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQINDYVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVKSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERPAQALLRDYDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMVDSGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYTVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRNGMAQQIAYEIHLEQQSEEELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFFDDMGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRNVQPHFLEFLLSLGWSVDVGKHPGWTGHVSTSWSINSCDDGEGPEQDEVISSEDIGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNVSDQDSDSNMDLMPGILKQPSLTLELFPNHTDNLNSSQRLSPSSRMKKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLADLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQEVGLKNCSS", "length": 1491 }, "evidence": [ { "id": "A0A8V0ZM03", "url": "https://omabrowser.org/oma/group/A0A8V0ZM03/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P86410-1", "protein_name": "Ral GTPase-activating protein subunit beta", "gene_name": "Ralgapb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYSEWRSLHLVIQNDQGHTSVLHSYPESVGREVANAVVRPLGQALGHSPVSASQSLLYTDKDVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKDSIPLPVIKEPNLYIQSILKHLQNLFVPRQEQGSSQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAVISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSAAVNTTPPHNRRHRAVTVNKATMKTSTVTTAHTSKVQHQASSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTASFIQILLSYKSSIATQASMEFRRKGSQMSTDTMVSNPVFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSSVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEALGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERPAQALLRDYGSTDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMVDLGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEMHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRNVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINSCDDGEGSEQDEVTSSEDVGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILKQPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS", "length": 1484 }, "evidence": [ { "id": "A0A8V0ZM03", "url": "https://omabrowser.org/oma/group/A0A8V0ZM03/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54TK4-1", "protein_name": "Rap-GAP domain-containing protein DDB_G0281809", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MITNSFTNNFQFIKDTGILKDFPLSVKRILVFQTVNFLLEPPNGNTQFIVTSKEHLQWIMEITEQGFLLPIEDSQIILQCIELYKKWLFDPKHKPTPLIDDDDEYFHKKIIEHLTLIFQPRSYPHYISMSNNNSNNNSNNSNININNNNNNNNNNNNNNNNNNNNNNNNNSNNTNSGSNNKESSNNNSPILSSSNSGSGSSLSLNKDKEGGGSNSGSFLGVNQQSSPPPQQISATTTAATSPTTPTTPIKDTLQQQFLQQEVGGFNEVVQQQQQQQQQQQQQQQQQQQQQQQQQSPSITTGTVKGSKYRESVMPGSSMMVQSSTTALYSSNNYSGNVQLPNISVKELIDSHSVLCQKVLQIYLEMSRGTYSRSFSTDTLEHWNRLMLSITDCILGIHSNSDEMLARNLCPLLLKTLFEVWLQSKTLNPTLWNSLTKYAQGWFHHMPTVNQWNLTCLALTTPLVQSIYTNDHQSKSTITIRLDETSIEFEKEYLYYAWNRILNLIGNPNQIKSPAIFSEAITGIFHLVSMFLSVTNDGNAILHIFGSWIFEAVKTIKPGFDEGISLGSEILLHIFLSCSRKIEFLPIYLSCFYTCISEALWCDGKILRDTIIHSQNIFSSGLPGSRILIPSYIRALNHILTAQGTNDPELRRCAIKILGSILCLPNRYETVKFHNFFPGRTIDPYPPLPNDIIDGKHNELTLPPNEINTYDDLKPHLAYLILSALNTEMSSSNLLTLIWYIMFYQLEYQHQHVKPYPDGKLITSSFIHQSINTILKKCSSFTNQWSHDVILSSFQLLSDLASQHQRIPNFLENASTVVRKLCKFITFKCKETNMSPETEDLISLGCSTIADWVVVSPWIFEGNYLTDTSTFYMVFNALSVAMGAKSPNDIISSNASISSSVSNTGISSIGGGGSSGSGNSSQPSSTGSGSGGVDSGSKSNSSSSSSSQPSSTGGSGNNSNSANGGSFKRPKPYINNNISPKVKEVAQCALKAIMSKISYFPNPYNATPTNTSSKVTESDIITQIKAKAEKHLGIKNFPSEQSLRFYAIGDSIIITVIDQPFTSTSSSPSDSYVTLIIRDMSGKSVINSQLAFLPFKQREISEIQQPITNEKESQIDDGDDSVPTNTTATTIDNTISNNNTTTTSNNSIKSTSNNKVPIKKRSQYNCNEEPFISSYIENVEDFGDLSSYIEKHIDENFTKLIDNQMEVEKQKLFANKYSLTPSITTHPPVLKTSFNGDCKLQQARILLTHLGFLNQENRNKLTPLENSVQFFQSLNMLDSVSERVQIKIPIIYVKKGDSTEDDIYNNVTSNTTQDYQDFIASLGWLVPISTHTGFLGDLDKKNLTHGQFTPYYATHSREMVFFVSTMMPNSDIANNSSQEHKKKLINKTNVSVIWFNGSIEVYEKTLLETFPHAIQIVITPLENDLFRLKTLRKATHSNRMKTGPVNDEIIISKHILANVIRLSVVNSNQSLLNLSSGDGKTQHIYTNRKKLISDITESFKHDMTIQKFYEFHFEPLDQSQLYQNTENLPMANNFKFVKTSSVNLFRKDRTQSALIGTFTLPPPPISPTISPQPSPHLSSSGGSWASSKGGSTQPTTPSGRTSNFLSRRPNLSQSEDQSHK", "length": 1619 }, "evidence": [ { "id": "A0A8V0ZM03", "url": "https://omabrowser.org/oma/group/A0A8V0ZM03/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86X10-1", "protein_name": "Ral GTPase-activating protein subunit beta", "gene_name": "RALGAPB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYSEWRSLHLVIQNDQGHTSVLHSYPESVGREVANAVVRPLGQVLGTPSVAGSENLLKTDKEVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKDSIPLPVIKEPNQYVQTILKHLQNLFVPRQEQGSSQIRLCLQVLRAIQKLARESSLMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPAFKVPDEDASLIPPEMDNECVAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMPQELNQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSAAVSTTPPHNRRHRAVTVNKATMKTSTVSTAHASKVQHQTSSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTAITTQASMEFRRKGSQMSTDTMVSNPMFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQINDYVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVKSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERPAQALLRDYALNTDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMVDSGDRKRAISSVCTYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNNEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEIHLEQQSEEELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRTVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINCCDDGEGSQQEVISSEDIGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILKQPSLTLELFPNHTDNLNSSQRLSPSSRMRKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQEVGLKNCSS", "length": 1494 }, "evidence": [ { "id": "A0A8V0ZM03", "url": "https://omabrowser.org/oma/group/A0A8V0ZM03/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BQZ4-1", "protein_name": "Ral GTPase-activating protein subunit beta", "gene_name": "Ralgapb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYSEWRSLHLVIQSDQGHTSVLHSYPESVGREVANAVVRPLGQALGTSSVAGSESLLKTDKEVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKDSIPLPIIKEPNLYVQSILKHLQNLFVPRQEQGSSQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAVISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSAAVNTTPPHNRRHRAVTVNKATMKTSTVTTAHTSKVQHQASSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDNSMTASFIQILLSYKSSIATQASMEFRRKGSQMSTDTMVSNPVFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSSVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERPAQALLRDYGSTDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMVDSGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEMHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRNVQPHFLEFLLSLGWSVDVGKHPGWTGHVSTSWSINSCDDGEGSEPDEITSSEDVGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILKQPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS", "length": 1484 }, "evidence": [ { "id": "A0A8V0ZM03", "url": "https://omabrowser.org/oma/group/A0A8V0ZM03/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X2JEC6-1", "protein_name": "Rap-GAP domain-containing protein", "gene_name": "CG32689", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYSEWASLSAQITANSCGAQCFSVLNKFPASAGREVVVSVVKQLGTNLGITQNAEPSHLVKDEEVKWCMDVICFGLSLPLQEHETIKDCVNVYCEWLTALHPQPRISVPKPICEDANLYARQIINHFHNLFVPRQGEILPFLYQTTLGADTIKRQAVLCHRVLRTLQQTAQISQLMDRQTWDTLLLFLLAINEILLAPPTVKDDVGDQLCERVLSVLFEVWLLACVRSFPSPSMWKTLQESCAMWRHRVALVDQWNRVNLALTARLLEFSYGPAFPQLKNADEDGQLIPIGMSNDCVAQTWYRFLRMIGNPTALCSPHIISKSSHFVQWALTHEKGAETHQHPCLQQLPQIFLNAMKGISSQVDAFLGVYQPPPQQTDGVVTNLLEIRHSLNEATSSTLQQFIHSSSATNIANQQNQPAHHHHHLHYPHLHLHGAGSFLRDNFMSNSASSALNAIMGHHGGHHGHHHQQQQQQQQQLQISASPTSSLTTSGSSAVGSTSAGGSHSAGVVGSISFGATESPGPGQASASATPTPPLQRRLAKSFSVAPTITQQKGLSKTSLIGLTGGGARNAISSSSTTTTNAGSTGGTGSGDGSAPAPLPTTPTSTSGPPSASSSINSLPLTSMGAGVELAVARPKCNSILHVFHEWLFEAAHIGGDTWRQNRKKQACEASKRPSSMIMEHRKGSISLSQPNSLNDPQSLPPTLTIDKYESGRAEAIGTLCKIFCAKKTGEEILPVYLARFYMALQQCLKITESRECDETLASILLHSSDLFRLDLDGINVLLPGFIAALEIVLPDKDLKLKTQSMVFNRTELRRSAINILLSIMVLPLHYQTLPIRDLTCESSEKMFTFIQLKSRLMNILMNALQVETDAQNTHMLLGGLLLCVQDAVTFEETELGGGNANLSQNSSGVQHHDANLLSSACSERSASLVSAGTASLGGQTTATMGAGSGSIRDTASAHDYPSLTISDDMSFEFGQELEGVTTYDNAHALFVRATYLVCHRLISSWKTDLNVSLAALELLSGLARLHIRETDALECKRAVKWICDYICYQCSRPPPAHSKDLHSTIVAAFQCTAAWLMQHPYLLQDKDCLQTVLEVVELGISGTKSQSKGTDIPKFKDEKELKPASMRVRDAAENLLTIILEQVGYFPSECGPESISSLLDELALMKHCNSMVPAAAASSEQAIAKFKYFVTENSTILALLEEPLGNDQDPQPTVTLLIRGPFGRHAWTMQLRHLPRSKSGIKYHAINPGRPIPMNDVTQRLDSEQKNFPDGVDKVQPCVADYSIPTIEQMREQYGTAVIRELESLLENQSIHEKLAWAEADTSADSLSHAQECVPPTVCHEFHAARLFLSHFGFLGFETRNPQNPAEALGNPPQRPLIVLDTKSAAFAADLDRLDKLSARTHDSVYVFYVKSGQTSAQQIIANMGEESSASHDPHFASMLQTLGWPVQVSEHSGWTGFAHNSWSLKGTPEEQLKSTANELNYNGSQRVLYWADVSSEIAFVVPTTWNLRYNSDTCDSGSISSTDQIGSSNVWTRGEADSAAGLAKSKSRNLSLELDTNRRDVKEPVPPTRRKGNVTKPTLLAQAPAKIFLVWLESYEDYLNFPLEDLLAYTRTGEELQTQQLPRASDCHVIFVHSLLSGLLRVKLQGPPGRMSFATPLVDGMVLSRRVVGNLVRQTALNISRRRRLDNDNYQPPHVRRRLKVQDIVQKYKMDLSEADLLAHLFQRAI", "length": 1728 }, "evidence": [ { "id": "A0A8V0ZM03", "url": "https://omabrowser.org/oma/group/A0A8V0ZM03/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03" } ], "pmid": "" }, { "name": "Ral protein signal transduction", "id": "GO:0032484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1280, "end_pos": 1282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1309, "end_pos": 1311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1376, "end_pos": 1378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 676, "end_pos": 678, "annotation": "n_glycosylation_sequon" }, { "start_pos": 927, "end_pos": 929, "annotation": "n_glycosylation_sequon" }, { "start_pos": 968, "end_pos": 970, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZM03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM03" }, { "id": "PS50085", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50085" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rap-GAP", "eco_id": "ECO_0000259", "start_pos": 1149, "end_pos": 1393, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 212, 362 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1280, "end_pos": 1282 }, { "start_pos": 1309, "end_pos": 1311 }, { "start_pos": 1376, "end_pos": 1378 }, { "start_pos": 173, "end_pos": 175 }, { "start_pos": 18, "end_pos": 20 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 676, "end_pos": 678 }, { "start_pos": 927, "end_pos": 929 }, { "start_pos": 968, "end_pos": 970 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJB7-1", "uniprot_ac": "A0A8V0ZJB7", "uniprot_id": "A0A8V0ZJB7_CHICK", "mass": { "chemical_mass": 28469.0, "monoisotopic_mass": 28469.0 }, "refseq": {}, "gene_names": [ { "name": "PSMC3IP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ] } ], "protein_names": [ { "name": "PSMC3 interacting protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], 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Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJA7", "url": "https://www.orthodb.org/?gene=A0A8V0ZJA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJB7", "url": "https://www.orthodb.org/?gene=A0A8V0ZJB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ49", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15938", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15938", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15938:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15938:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZJA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ49-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SCPVSRELTLKASIEEQPSIAGQLSCGDRRHRNCPRSAAGSGAEPDHLRADRGRKPRSFAVRRAGSASRRLSGAREQDEQRARGPRGGRRGHRYPAALPAGAEPAVQRPGRLREPAAGARAGQGGRGEGAGAAGAAGPHPREGLRQAEGVLRRPELKDLNSTMTTADMAREVEELKKDCASYTEKLERIKSATNQVTPEEKEKVCSEQKLYCKEWRRRKRMATELLDAILEGYPKSKKQFFEEVGIETDEDHNVTLPTAV", "length": 260, "header": "tr|A0A8V0ZJB7-1|A0A8V0ZJB7_CHICK Isoform 1 of PSMC3 interacting protein OS=Gallus gallus OX=9031 GN=PSMC3IP PE=4 SV=1 CANONICAL=A0A8V0ZJB7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7/entry#A0A8V0ZJA7-1", "sequence": { "sequence": "MSKGREGPAAGGGATAILLRYLREQNRPYSAQDVFGNLQREHGLGKAAVVKALEQLAQQGHIREKAYGKQKVYFADQEQLPAAGDAELRVLDADISARSAELQALLQGCRQLEAELKDLNSTMTTADMAREVEELKKDCASYTEKLERIKSATNQVTPEEKEKVCSEQKLYCKEWRRRKRMATELLDAILEGYPKSKKQFFEHFVLVQEEVGIETDEDHNVTLPTAV", "length": 227, "header": "tr|A0A8V0ZJA7-1|A0A8V0ZJB7_CHICK Computationally mapped isoform of PSMC3 interacting protein OS=Gallus gallus OX=9031 GN=PSMC3IP PE=4 SV=1 CANONICAL=A0A8V0ZJB7-1" }, "locus": { "chromosome": "27", "start_pos": 4972413, "end_pos": 4970476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051715.1", "url": "https://www.ensembl.org/id/ENSGALT00010051715.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030850.1", "url": "https://www.ensembl.org/id/ENSGALP00010030850.1" } ] } }, { "isoform_ac": "A0A8V0ZJB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7/entry#A0A8V0ZJB7-1", "sequence": { "sequence": "SCPVSRELTLKASIEEQPSIAGQLSCGDRRHRNCPRSAAGSGAEPDHLRADRGRKPRSFAVRRAGSASRRLSGAREQDEQRARGPRGGRRGHRYPAALPAGAEPAVQRPGRLREPAAGARAGQGGRGEGAGAAGAAGPHPREGLRQAEGVLRRPELKDLNSTMTTADMAREVEELKKDCASYTEKLERIKSATNQVTPEEKEKVCSEQKLYCKEWRRRKRMATELLDAILEGYPKSKKQFFEEVGIETDEDHNVTLPTAV", "length": 260, "header": "tr|A0A8V0ZJB7-1|A0A8V0ZJB7_CHICK Isoform 1 of PSMC3 interacting protein OS=Gallus gallus OX=9031 GN=PSMC3IP PE=4 SV=1 CANONICAL=A0A8V0ZJB7-1" }, "locus": { "chromosome": "27", "start_pos": 4972645, "end_pos": 4970476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051737.1", "url": "https://www.ensembl.org/id/ENSGALT00010051737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030860.1", "url": "https://www.ensembl.org/id/ENSGALP00010030860.1" } ] } }, { "isoform_ac": "A0A8V0ZQ49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7/entry#A0A8V0ZQ49-1", "sequence": { "sequence": "QLSCGDRRHRNCPRSAAGSGAEPDHLRADRGRKPRSFAVRRAGSASRRLSGAREQDEQRARGPRGGRRGHRYPAALPAGAEPAVQRPGRLREPAAGARAGQGGRGEGAGAAGAAGPHPREGLRQAEGVLRRPVEELKKDCASYTEKLERIKSATNQVTPEEKEKVCSEQKLYCKEWRRRKRMATELLDAILEGYPKSKKQFFEHFVLVQEEVGIETDEDHNVTLPTAV", "length": 228, "header": "tr|A0A8V0ZQ49-1|A0A8V0ZQ49_CHICK Computationally mapped isoform of PSMC3 interacting protein OS=Gallus gallus OX=9031 GN=PSMC3IP PE=4 SV=1 CANONICAL=A0A8V0ZJB7-1" }, "locus": { "chromosome": "27", "start_pos": 4972579, "end_pos": 4970476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051741.1", "url": "https://www.ensembl.org/id/ENSGALT00010051741.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030863.1", "url": "https://www.ensembl.org/id/ENSGALP00010030863.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" }, { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" }, { "name": "DNA recombinase auxiliary factor complex", "id": "GO:0120231", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120231", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" }, { "name": "meiotic joint molecule formation", "id": "GO:0000709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000709", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" }, { "name": "meiotic strand invasion involved in reciprocal meiotic recombination", "id": "GO:0010774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" }, { "name": "recombinase activator activity", "id": "GO:0120230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120230", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB7" }, { "id": "PF18517", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18517" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Leucine zipper with capping helix", "eco_id": "ECO_0000259", "start_pos": 196, "end_pos": 252, "start_aa": "Val", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 253, "end_pos": 255 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLF9-1", "uniprot_ac": "A0A8V0ZLF9", "uniprot_id": "A0A8V0ZLF9_CHICK", "mass": { "chemical_mass": 29086.0, "monoisotopic_mass": 29086.0 }, "refseq": { "ac": "NP_001008470", "name": "CD82 antigen", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008470" }, "gene_names": [ { "name": "CD82", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9" } ] }, { "name": "CD82", "type": "synonym", "evidence": [ { "id": "NP_001008470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008470" } ] } ], "protein_names": [ { "name": "Tetraspanin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9/entry#names_and_taxonomy" } ] }, { "name": "CD82 antigen", "type": "synonym", "evidence": [ { "id": "NP_001008470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008470" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719947.1, HAEK01009811.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000214.1. On Sep 23, 2021 this sequence version replaced NP_001008470.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008470" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9", "locus": { "chromosome": "5", "start_pos": 21543221, "end_pos": 21509240, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021703", "url": "https://www.ensembl.org/id/ENSGALG00010021703" } ] } } ], "crossref": [ { "id": "A0A8V0ZLF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423172", "url": "https://www.ncbi.nlm.nih.gov/gene/423172", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018503", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018503", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423172", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423172", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TTEHAWD", "url": "https://omabrowser.org/oma/group/TTEHAWD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJT5", "url": "https://www.orthodb.org/?gene=A0A8V0ZJT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLF9", "url": "https://www.orthodb.org/?gene=A0A8V0ZLF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLG4", "url": "https://www.orthodb.org/?gene=A0A8V0ZLG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLN4", "url": "https://www.orthodb.org/?gene=A0A8V0ZLN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS77", "url": "https://www.orthodb.org/?gene=A0A8V0ZS77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001008470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008470", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLN4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSGCLKVTKYFLFLFNLLFLILGAVILGFGIWILADKTSFISVLQNSSPSVRTGAYILVGVGSLTMLMGFLGCLGAVNEIRCLLGLYFTCLMMILITQVAAGLVIYFQQEELKGELSRIVEKLIGDYDPVNGEDKNLQDAWDYVQKQLTCCGWNGAEEWEKNPILINRSMTAYPCSCSNSSKDAEENTGFCTLDVVVNETATHANWPVHRQGCVDGVQDWLKDNLGIILGVCTGVAVVELLGMILSISLCKNIHSEDYTKVPKS", "length": 265, "header": "tr|A0A8V0ZLF9-1|A0A8V0ZLF9_CHICK Isoform 1 of Tetraspanin OS=Gallus gallus OX=9031 GN=CD82 PE=1 SV=1 CANONICAL=A0A8V0ZLF9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9/entry#A0A8V0ZJT5-1", "sequence": { "sequence": "MGSGCLKVTKYFLFLFNLLFLILGAVILGFGIWILADKTSFISVLQNSSPSVRTGAYILVGVGSLTMLMGFLGCLGAVNEIRCLLGLLKGELSRIVEKLIGDYDPVNGEDKNLQDAWDYVQKQLTCCGWNGAEEWEKNPILINRSMTAYPCSCSNSSKDAEENTGFCTLDVVVNETATHANWPVHRQGCVDGVQDWLKDNLGIILGVCTGVAVVELLGMILSISLCKNIHSEDYTKVPKS", "length": 240, "header": "tr|A0A8V0ZJT5-1|A0A8V0ZLF9_CHICK Computationally mapped isoform of Tetraspanin OS=Gallus gallus OX=9031 GN=CD82 PE=1 SV=1 CANONICAL=A0A8V0ZLF9-1" }, "locus": { "chromosome": "5", "start_pos": 21541164, "end_pos": 21524437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052740.1", "url": "https://www.ensembl.org/id/ENSGALT00010052740.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031646.1", "url": "https://www.ensembl.org/id/ENSGALP00010031646.1" } ] } }, { "isoform_ac": "A0A8V0ZLF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9/entry#A0A8V0ZLF9-1", "sequence": { "sequence": "MGSGCLKVTKYFLFLFNLLFLILGAVILGFGIWILADKTSFISVLQNSSPSVRTGAYILVGVGSLTMLMGFLGCLGAVNEIRCLLGLYFTCLMMILITQVAAGLVIYFQQEELKGELSRIVEKLIGDYDPVNGEDKNLQDAWDYVQKQLTCCGWNGAEEWEKNPILINRSMTAYPCSCSNSSKDAEENTGFCTLDVVVNETATHANWPVHRQGCVDGVQDWLKDNLGIILGVCTGVAVVELLGMILSISLCKNIHSEDYTKVPKS", "length": 265, "header": "tr|A0A8V0ZLF9-1|A0A8V0ZLF9_CHICK Isoform 1 of Tetraspanin OS=Gallus gallus OX=9031 GN=CD82 PE=1 SV=1 CANONICAL=A0A8V0ZLF9-1" }, "locus": { "chromosome": "5", "start_pos": 21541164, "end_pos": 21524437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052737.1", "url": "https://www.ensembl.org/id/ENSGALT00010052737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031643.1", "url": "https://www.ensembl.org/id/ENSGALP00010031643.1" } ] } }, { "isoform_ac": "A0A8V0ZLG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9/entry#A0A8V0ZLG4-1", "sequence": { "sequence": "MGSGCLKVTKYFLFLFNLLFLILGAVILGFGIWILADKTSFISVLQNSSPSVRTGAYILVGVGSLTMLMGFLGCLGAVNEIRCLLGLYFTCLMMILITQVAAGLVIYFQQEELKGELSRIVEKLIGDYDPVNGEDKNLQDAWDYVQKQLTCCGWNGAEEWEKNPILINRSMTAYPCSCSNSSKDAEENTGFCTLDVVVNETATHANWPVHRQDWLKDNLGIILGVCTGVAVVELLGMILSISLCKNIHSEDYTKVPKS", "length": 258, "header": "tr|A0A8V0ZLG4-1|A0A8V0ZLG4_CHICK Computationally mapped isoform of Tetraspanin OS=Gallus gallus OX=9031 GN=CD82 PE=1 SV=1 CANONICAL=A0A8V0ZLF9-1" }, "locus": { "chromosome": "5", "start_pos": 21541164, "end_pos": 21524437, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052742.1", "url": "https://www.ensembl.org/id/ENSGALT00010052742.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031648.1", "url": "https://www.ensembl.org/id/ENSGALP00010031648.1" } ] } }, { "isoform_ac": "A0A8V0ZLN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9/entry#A0A8V0ZLN4-1", "sequence": { "sequence": "MPQPGSGIRKAFCSREPACKILGAVILGFGIWILADKTSFISVLQNSSPSVRTGAYILVGVGSLTMLMGFLGCLGAVNEIRCLLGLYFTCLMMILITQVAAGLVIYFQQEELKGELSRIVEKLIGDYDPVNGEDKNLQDAWDYVQKQLTCCGWNGAEEWEKNPILINRSMTAYPCSCSNSSKDAEENTGFCTLDVVVNETATHANWPVHRQGCVDGVQDWLKDNLGIILGVCTGVAVVELLGMILSISLCKNIHSEDYTKVPKS", "length": 264, "header": "tr|A0A8V0ZLN4-1|A0A8V0ZLN4_CHICK Computationally mapped isoform of Tetraspanin OS=Gallus gallus OX=9031 GN=CD82 PE=1 SV=1 CANONICAL=A0A8V0ZLF9-1" }, "locus": { "chromosome": "5", "start_pos": 21541164, "end_pos": 21528385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052730.1", "url": "https://www.ensembl.org/id/ENSGALT00010052730.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031636.1", "url": "https://www.ensembl.org/id/ENSGALP00010031636.1" } ] } }, { "isoform_ac": "A0A8V0ZS77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9/entry#A0A8V0ZS77-1", "sequence": { "sequence": "MPQHKILGAVILGFGIWILADKTSFISVLQNSSPSVRTGAYILVGVGSLTMLMGFLGCLGAVNEIRCLLGLYFTCLMMILITQVAAGLVIYFQQEELKGELSRIVEKLIGDYDPVNGEDKNLQDAWDYVQKQLTCCGWNGAEEWEKNPILINRSMTAYPCSCSNSSKDAEENTGFCTLDVVVNETATHANWPVHRQGCVDGVQDWLKDNLGIILGVCTGVAVVELLGMILSISLCKNIHSEDYTKVPKS", "length": 249, "header": "tr|A0A8V0ZS77-1|A0A8V0ZLF9_CHICK Computationally mapped isoform of Tetraspanin OS=Gallus gallus OX=9031 GN=CD82 PE=1 SV=1 CANONICAL=A0A8V0ZLF9-1" }, "locus": { "chromosome": "5", "start_pos": 21541164, "end_pos": 21525058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052733.1", "url": "https://www.ensembl.org/id/ENSGALT00010052733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031640.1", "url": "https://www.ensembl.org/id/ENSGALP00010031640.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423172", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423172", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P27701-1", "protein_name": "CD82 antigen", "gene_name": "CD82", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRHVHSEDYSKVPKY", "length": 267 }, "evidence": [ { "id": "A0A8V0ZLF9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLF9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P40237-1", "protein_name": "CD82 antigen", "gene_name": "Cd82", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAGCVKVTKYFLFLFNLLFFILGAVILGFGVWILADKNSFISVLQTSSSSLQVGAYVFIGVGAITIVMGFLGCIGAVNEVRCLLGLYFVFLLLILIAQVTVGVLFYFNADKLKKEMGNTVMDIIRNYTANATSSREEAWDYVQAQVKCCGWVSHYNWTENEELMGFTKTTYPCSCEKIKEEDNQLIVKKGFCEADNSTVSENNPEDWPVNTEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLFLSICLCRYIHSEDYSKVPKY", "length": 266 }, "evidence": [ { "id": "A0A8V0ZLF9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLF9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 180, "end_pos": 182 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKX2-1", "uniprot_ac": "A0A8V0ZKX2", "uniprot_id": "A0A8V0ZKX2_CHICK", "mass": { "chemical_mass": 10105.0, "monoisotopic_mass": 10105.0 }, "refseq": {}, "gene_names": [ { "name": "CXCL12", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX2" } ] } ], "protein_names": [ { "name": "Stromal cell-derived factor 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX2/entry#names_and_taxonomy" } ] }, { "name": "C-X-C motif chemokine 12", "type": "synonym", "evidence": [ { "id": 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"MGTRRGGPHLSAPRLALGMPWQGTAMAPKWLPDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLVEIGLAKDDQLKVHGF", "length": 135, "header": "tr|A0A8V0ZJ52-1|A0A8V0ZJ52_CHICK Isoform 1 of Eukaryotic translation initiation factor 1 OS=Gallus gallus OX=9031 GN=EIF1 PE=3 SV=1 CANONICAL=A0A8V0ZJ52-1" }, "locus": { "chromosome": "27", "start_pos": 4641499, "end_pos": 4635525, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055180.1", "url": "https://www.ensembl.org/id/ENSGALT00010055180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033383.1", "url": "https://www.ensembl.org/id/ENSGALP00010033383.1" } ] } }, { "isoform_ac": "A0A8V0ZPG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52/entry#A0A8V0ZPG8-1", "sequence": { "sequence": "HVTTRKSDRCFRNTREVPKHSQASDPFYPARDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLVEIGLAKDDQLKVHGF", "length": 134, "header": "tr|A0A8V0ZPG8-1|A0A8V0ZJ52_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 1 OS=Gallus gallus OX=9031 GN=EIF1 PE=3 SV=1 CANONICAL=A0A8V0ZJ52-1" }, "locus": { "chromosome": "27", "start_pos": 4641499, "end_pos": 4639219, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055168.1", "url": "https://www.ensembl.org/id/ENSGALT00010055168.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033375.1", "url": "https://www.ensembl.org/id/ENSGALP00010033375.1" } ] } }, { "isoform_ac": "A0A8V0ZWX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52/entry#A0A8V0ZWX3-1", "sequence": { "sequence": "MSAIQNLQPFDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKVGCGRCVGPGGQRHTGGCGAGVAVPGFVVLRGPSSFPRNLPAMVL", "length": 110, "header": "tr|A0A8V0ZWX3-1|A0A8V0ZJ52_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 1 OS=Gallus gallus OX=9031 GN=EIF1 PE=3 SV=1 CANONICAL=A0A8V0ZJ52-1" }, "locus": { "chromosome": "27", "start_pos": 4641094, "end_pos": 4640546, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055174.1", "url": "https://www.ensembl.org/id/ENSGALT00010055174.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033379.1", "url": "https://www.ensembl.org/id/ENSGALP00010033379.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52" } ], "pmid": "" }, { "name": "regulation of primary metabolic process", "id": "GO:0080090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52" } ], "pmid": "" }, { "name": "regulation of translational initiation", "id": "GO:0006446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52" } ], "pmid": "" }, { "name": "ribosomal small subunit binding", "id": "GO:0043024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52" } ], "pmid": "" }, { "name": "eukaryotic 43S preinitiation complex", "id": "GO:0016282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016282", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52" } ], "pmid": "" }, { "name": "eukaryotic 48S preinitiation complex", "id": "GO:0033290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033290", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52" } ], "pmid": "" }, { "name": "multi-eIF complex", "id": "GO:0043614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043614", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJ52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ52" }, { "id": "PS50296", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50296" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUI1", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 123, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJT1-1", "uniprot_ac": "A0A8V0ZJT1", "uniprot_id": "A0A8V0ZJT1_CHICK", "mass": { "chemical_mass": 52965.0, "monoisotopic_mass": 52965.0 }, "refseq": { "ac": "XP_004942796", "name": "mRNA N(3)-methylcytidine methyltransferase METTL8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942796" }, "gene_names": [ { "name": "METTL8", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" } ] }, { "name": "METTL8", "type": "synonym", "evidence": [ { "id": "XP_004942796", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942796" } ] } ], "protein_names": [ { "name": "Methyltransferase 8, tRNA N3-cytidine", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1/entry#names_and_taxonomy" } ] }, { "name": "mRNA N(3)-methylcytidine methyltransferase METTL8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004942796", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942796" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004942796.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942796", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942796" } ] }, { "annotation": "S-adenosyl-L-methionine-dependent methyltransferase.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ75#function" }, { "database": "UniProtKB", "id": "PIRNR037755", "url": "https://www.uniprot.org/uniprotkb/PIRNR037755#function" }, { "database": "UniProtKB", "id": "A0A8V0ZXL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXL6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "METTL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1", "locus": { "chromosome": "7", "start_pos": 17688504, "end_pos": 17659083, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022816", "url": "https://www.ensembl.org/id/ENSGALG00010022816" } ] } } ], "crossref": [ { "id": "A0A8V0ZJT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424154", "url": "https://www.ncbi.nlm.nih.gov/gene/424154", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424154", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424154", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDRMQSV", "url": "https://omabrowser.org/oma/group/PDRMQSV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22809:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22809:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08242", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08242", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942796", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942796", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQASCFLKVVTINCICQKRKWTSGDKLVFFPPMAQMGSPNKMNFITRLSALCLRKKNNMQQRYQSSRRPAVPLGSRILTDPSKVFEHNMWDHMQWSQEEEEHAKEKAAENSLVKVHLEDQDKYEREASKYWNEFYKTHKNNFFKDRNWLFLEFPEILPEKMREQLKIEGRPSELTKINITNSFSQEKEMFEEGEKYWKKNTGDDSTSEKGYNKKQPKCIADRPWGKSNEEEVNVLESFPGSDATYRILEVGCGAGNSVFPILKVLCNTPGTFLYCCDFASGAVELVKSHSSYNSAWCSAFVHDVCDDALPYPFPDEILDVILLVFVLSTIHPDRMQQVVNRLVKLLKPGGILLFRDYGRYDTAQLRFKKGHCLSENFYVRGDGTRVYFFTKEEVQSMFTLAGLTEIQNLVDRRLQVNRKKKVKMQRVWVQGKFQKPLLLSLNNPEETTKRHPYG", "length": 455, "header": "tr|A0A8V0ZJT1-1|A0A8V0ZJT1_CHICK Isoform 1 of Methyltransferase 8, tRNA N3-cytidine OS=Gallus gallus OX=9031 GN=METTL8 PE=3 SV=1 CANONICAL=A0A8V0ZJT1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1/entry#A0A8V0ZJT1-1", "sequence": { "sequence": "MEQASCFLKVVTINCICQKRKWTSGDKLVFFPPMAQMGSPNKMNFITRLSALCLRKKNNMQQRYQSSRRPAVPLGSRILTDPSKVFEHNMWDHMQWSQEEEEHAKEKAAENSLVKVHLEDQDKYEREASKYWNEFYKTHKNNFFKDRNWLFLEFPEILPEKMREQLKIEGRPSELTKINITNSFSQEKEMFEEGEKYWKKNTGDDSTSEKGYNKKQPKCIADRPWGKSNEEEVNVLESFPGSDATYRILEVGCGAGNSVFPILKVLCNTPGTFLYCCDFASGAVELVKSHSSYNSAWCSAFVHDVCDDALPYPFPDEILDVILLVFVLSTIHPDRMQQVVNRLVKLLKPGGILLFRDYGRYDTAQLRFKKGHCLSENFYVRGDGTRVYFFTKEEVQSMFTLAGLTEIQNLVDRRLQVNRKKKVKMQRVWVQGKFQKPLLLSLNNPEETTKRHPYG", "length": 455, "header": "tr|A0A8V0ZJT1-1|A0A8V0ZJT1_CHICK Isoform 1 of Methyltransferase 8, tRNA N3-cytidine OS=Gallus gallus OX=9031 GN=METTL8 PE=3 SV=1 CANONICAL=A0A8V0ZJT1-1" }, "locus": { "chromosome": "7", "start_pos": 17685029, "end_pos": 17663094, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055491.1", "url": "https://www.ensembl.org/id/ENSGALT00010055491.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033609.1", "url": "https://www.ensembl.org/id/ENSGALP00010033609.1" } ] } }, { "isoform_ac": "A0A8V0ZQ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1/entry#A0A8V0ZQ75-1", "sequence": { "sequence": "MAQMGSPNKMNFITRLSALCLRKKNNMQQRYQSSRRPAVPLGSRILTDPSKVFEHNMWDHMQWSQEEEEHAKEKAAENSLVKVHLEDQDKYEREAKILPEKMREQLKIEGRPSELTKINITNSFSQEKEMFEEGEKYWKKNTGDDSTSEKGYNKKQPKCIADRPWGKSNEEEVNVLESFPGSDATYRILEVGCGAGNSVFPILKVLCNTPGTFLYCCDFASGAVELVKSHSSYNSAWCSAFVHDVCDDALPYPFPDEILDVILLVFVLSTIHPDRMQQVVNRLVKLLKPGGILLFRDYGRYDTAQLRFKKGHCLSENFYVRGDGTRVYFFTKEEVQSMFTLAGLTEIQNLVDRRLQVNRKKKVKMQRVWVQGKFQKPLLLSLNNPEETTKRHPYG", "length": 395, "header": "tr|A0A8V0ZQ75-1|A0A8V0ZJT1_CHICK Computationally mapped isoform of Methyltransferase 8, tRNA N3-cytidine OS=Gallus gallus OX=9031 GN=METTL8 PE=3 SV=1 CANONICAL=A0A8V0ZJT1-1" }, "locus": { "chromosome": "7", "start_pos": 17685029, "end_pos": 17663294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055498.1", "url": "https://www.ensembl.org/id/ENSGALT00010055498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033616.1", "url": "https://www.ensembl.org/id/ENSGALP00010033616.1" } ] } }, { "isoform_ac": "A0A8V0ZXL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1/entry#A0A8V0ZXL6-1", "sequence": { "sequence": "MAQMGSPNKMNFITRLSALCLRKKNNMQQRYQSSRRPAVPLGSRILTDPSKVFEHNMWDHMQWSQEEEEHAKEKAAENSLVKVHLEDQDKYEREASKYWNEFYKTHKNNFFKDRNWLFLEFPEILPEKMREQLKIEGRPSELTKINITNSFSQEKEMFEEGEKYWKKNTGDDSTSEKGYNKKQPKCIADRPWGKSNEEEVNVLESFPGSDATYRILEVGCGAGNSVFPILKVLCNTPGTFLYCCDFASGAVELVKSHSSYNSAWCSAFVHDVCDDALPYPFPDEILDVILLVFVLSTIHPDRMQQVVNRLVKLLKPGGILLFRDYGRYDTAQLRFKKGHCLSENFYVRGDGTRVYFFTKEEVQSMFTLAGLTEIQNLVDRRLQVNRKKKVKMQRVWVQGKFQKPLLLSLNNPEETTKRHPYG", "length": 422, "header": "tr|A0A8V0ZXL6-1|A0A8V0ZJT1_CHICK Computationally mapped isoform of Methyltransferase 8, tRNA N3-cytidine OS=Gallus gallus OX=9031 GN=METTL8 PE=3 SV=1 CANONICAL=A0A8V0ZJT1-1" }, "locus": { "chromosome": "7", "start_pos": 17685029, "end_pos": 17663294, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055502.1", "url": "https://www.ensembl.org/id/ENSGALT00010055502.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033620.1", "url": "https://www.ensembl.org/id/ENSGALP00010033620.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424154", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424154", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MY71-1", "protein_name": "tRNA N(3)-cytidine methyltransferase", "gene_name": "METTL8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNVIWRNYISCPRMRKVPHRYQSGCHPVAPLGSRILTDPTKVFEHNMWDHMQWSKEEEAAARKKVEENSAVRVLLEEQVKYESEASKYWDTFYKIHKNKFFKDRNWLLREFPEILPVGQKTEEKVKELSWNHVKINAESFFSKMHCPTMPEEKNHYKESSGSSDGQSKAGSDFSKLDSEEYRERPLKTELFPGSNAAFRILEVGCGAGNSVFPILNTLQNVPEFFLYCCDFASGAVELVKSHASYRAAQCCAFVHDVCDHGLPYPFPDGTLDVILLVFVLSSIHPDRMQGVINRLSKLLKPGGMLLFRDYGRYDKTQLRFKRGHCLSENFYVRGDGTRAYFFTKGEVHNMFCKAGLDEKQNLVDRRLQVNRKKKVKMHRVWVQGKFQKPLHLTQKSSNLVFSVLSHE", "length": 407 }, "evidence": [ { "id": "A0A8V0ZJT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJT1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2AUU0-1", "protein_name": "tRNA N(3)-cytidine methyltransferase METTL8, mitochondrial", "gene_name": "Mettl8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVIWRSCICRLRQGKVPHRCQSGVHPVAPLGSRILTDPAKVFEHNMWDHMQWSKEEEDAARKKVEENSATRVAPEEQVKFESDANKYWDIFYQTHKNKFFKNRNWLLREFPEILPVNQNTKEKVGESSWDQVGSSISRTQGTETHCQESFVSPEPGSRGRSAPDPDLEEYSKGPGKTEPFPGSNATFRILEVGCGAGNSVFPILNTLQNIPGSFLYCCDFASEAVELVKSHESYSEAQCSAFIHDVCDDGLAYPFPDGILDVVLLVFVLSSIHPDRALFI", "length": 281 }, "evidence": [ { "id": "A0A8V0ZJT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZFN6-1", "protein_name": "tRNA N(3)-cytidine methyltransferase", "gene_name": "Mettl8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MINYGILKVLFGMNVIWRNCICRLRQGKVPHRCQSGVHPVAPLGSRILTDPTKVFEHNMWDHMQWSKEEEDEARKKVEENSATRVAPEEQVKFENAANKYWDTFYQTHKNKFFKNRNWLLREFPEILPVDQNTKEKLGESSWDPARSSISRTQGTETHRQETFVSSEPGSRERSASNPDLEEYSRGPRKAEQFPGSKATFRILEVGCGAGNSVFPILNTLQNIPGSFLYCCDFAPEAVELVKSHEAYSEAHCSAFIHDVCDDGLAYPFPDGTLDVILLVFVLSSIHPDRMQAVIHRLSRLLKPGGMLLFRDHGRYDNAQLRFKKGRCLSENFYVRGDGTRAYFFTKGEIHRMFCEAGLHEKQNLVDHRLQVNRKKQIQMHRVWVQGKFQKPSCWTPRSADEHALPSPD", "length": 408 }, "evidence": [ { "id": "A0A8V0ZJT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJT1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S1U3-1", "protein_name": "tRNA N(3)-cytidine methyltransferase", "gene_name": "METTL8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCQKVLSVMWRNYISCRRIRKLPHRYQSHYHPAAPLGSRILTDPAKVFEHNMWDHMQWSKEEEAAARKKVEENSAVRVLLEEQVKYENEASKYWDTFYKIHKNKFFKDRNWLLREFPEILPINQNTEEKTKELPQDHVKMNAPNCFSRMYCTTVPEEKNYKKISGLSDGQSKAGSDFSNLDSKEDRKGPSKTELFPGSNATFRILEVGCGAGNSVFPILNTLQNTPESFLYCCDFASGAVELVKSHPSYRAAQCCAFVHDVCDDGLAYPFPDGILDVILLVFVLSSIHPDRMQGVVKQLSKLLKPGGMLLFRDYGRYDKTQLRFKRGHCLSENFYVRGDGTRAYFFTKGEVHDMFCKAGLDEKQNLVDRRLQVNRKKKVKMHRVWVQGKFQKPLYLTQKSSKRVFSVLSHG", "length": 411 }, "evidence": [ { "id": "A0A8V0ZJT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJT1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9H825-1", "protein_name": "tRNA N(3)-cytidine methyltransferase METTL8, mitochondrial", "gene_name": "METTL8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNMIWRNSISCLRLGKVPHRYQSGYHPVAPLGSRILTDPAKVFEHNMWDHMQWSKEEEAAARKKVKENSAVRVLLEEQVKYEREASKYWDTFYKIHKNKFFKDRNWLLREFPEILPVDQKPEEKARESSWDHVKTSATNRFSRMHCPTVPDEKNHYEKSSGSSEGQSKTESDFSNLDSEKHKKGPMETGLFPGSNATFRILEVGCGAGNSVFPILNTLENSPESFLYCCDFASGAVELVKSHSSYRATQCFAFVHDVCDDGLPYPFPDGILDVILLVFVLSSIHPDRTLFI", "length": 291 }, "evidence": [ { "id": "A0A8V0ZJT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJT1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" } ], "pmid": "" }, { "name": "histone acetyltransferase activity", "id": "GO:0004402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004402", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" } ], "pmid": "" }, { "name": "mRNA methyltransferase activity", "id": "GO:0008174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008174", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" } ], "pmid": "" }, { "name": "tRNA (cytidine-3-)-methyltransferase activity", "id": "GO:0052735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJT1" }, { "id": "PF08242", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08242" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase type 12", "eco_id": "ECO_0000259", "start_pos": 249, "end_pos": 353, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 179, "end_pos": 181 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZK11-1", "uniprot_ac": "A0A8V0ZK11", "uniprot_id": "A0A8V0ZK11_CHICK", "mass": { "chemical_mass": 38260.0, "monoisotopic_mass": 38260.0 }, "refseq": {}, "gene_names": [ { "name": "C11orf49", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11" } ] } ], "protein_names": [ { "name": "Centriolar satellite-associated tubulin polyglutamylase complex regulator 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Regulator of the tubulin polyglutamylase complex (TPGC) that controls cytoskeletal organization, nuclear shape, and cilium disassembly by balancing microtubule and actin assembly. Regulates the assembly and stability of the TPGC and thereby modulates polyglutamylation of the microtubule, which antagonizes MAP4 binding.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQE6#function" }, { "database": "UniProtKB", "id": "ARBA00045673", "url": "https://www.uniprot.org/uniprotkb/ARBA00045673#function" }, { "database": "UniProtKB", "id": "A0A8V0ZK11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11#function" }, { "database": "UniProtKB", "id": "A0A8V0ZK16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK16#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C11orf49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZK11", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZK11", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22959", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22959", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423188", "url": "https://www.ncbi.nlm.nih.gov/gene/423188", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423188", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423188", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KATPHNR", "url": "https://omabrowser.org/oma/group/KATPHNR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK11", "url": "https://www.orthodb.org/?gene=A0A8V0ZK11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK16", "url": "https://www.orthodb.org/?gene=A0A8V0ZK16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQE6", "url": "https://www.orthodb.org/?gene=A0A8V0ZQE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34252:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34252:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZK11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSQLCLFFLHLQNLKGFEKAQRHVLTYMEDAVSQLLENREDISQYGIARFFTEYFNSVRQGTHILFREFSFVQATPHNRASFLRTFWRCFRTVGKNGDLLTAQEYHCLLQLLCPDFPMELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLESVAAIYQDLLAGKNPNTVIVPTSSSGQHRQRQPPNDCNLPDGVEASLFYQCVESLCDRSKYSCPPSALVKEVLSTTQRLTFSGFLMTLAKDQGINRALGALPDKDLFLDPAMDQELEKLVAQVSGLSISAPTSSSGDTANFHGRNSPRINSPWKPLHHRRKIDAESEGSNEETDSSEN", "length": 338, "header": "tr|A0A8V0ZK11-1|A0A8V0ZK11_CHICK Isoform 1 of Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 OS=Gallus gallus OX=9031 GN=C11orf49 PE=3 SV=1 CANONICAL=A0A8V0ZK11-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZK11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11/entry#A0A8V0ZK11-1", "sequence": { "sequence": "MAVSQLCLFFLHLQNLKGFEKAQRHVLTYMEDAVSQLLENREDISQYGIARFFTEYFNSVRQGTHILFREFSFVQATPHNRASFLRTFWRCFRTVGKNGDLLTAQEYHCLLQLLCPDFPMELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLESVAAIYQDLLAGKNPNTVIVPTSSSGQHRQRQPPNDCNLPDGVEASLFYQCVESLCDRSKYSCPPSALVKEVLSTTQRLTFSGFLMTLAKDQGINRALGALPDKDLFLDPAMDQELEKLVAQVSGLSISAPTSSSGDTANFHGRNSPRINSPWKPLHHRRKIDAESEGSNEETDSSEN", "length": 338, "header": "tr|A0A8V0ZK11-1|A0A8V0ZK11_CHICK Isoform 1 of Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 OS=Gallus gallus OX=9031 GN=C11orf49 PE=3 SV=1 CANONICAL=A0A8V0ZK11-1" }, "locus": { "chromosome": "5", "start_pos": 22815372, "end_pos": 22745087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055621.1", "url": "https://www.ensembl.org/id/ENSGALT00010055621.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033694.1", "url": "https://www.ensembl.org/id/ENSGALP00010033694.1" } ] } }, { "isoform_ac": "A0A8V0ZK16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11/entry#A0A8V0ZK16-1", "sequence": { "sequence": "MALPGSSLNNLLTAQEYHCLLQLLCPDFPMELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLESVAAIYQDLLAGKNPNTVIVPTSSSGQHRQRQPPNDCNLPDGVEASLFYQCVESLCDRSKYSCPPSALVKEVLSTTQRLTFSGFLMTLAKDQGINRALGALPDKDLFLDPAMDQELEKLVAQVSGLSISAPTSSSGDTANFHGRNSPRINSPWKPLHHRRKIDAESEGSNEETDSSEN", "length": 248, "header": "tr|A0A8V0ZK16-1|A0A8V0ZK16_CHICK Computationally mapped isoform of Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 OS=Gallus gallus OX=9031 GN=C11orf49 PE=3 SV=1 CANONICAL=A0A8V0ZK11-1" }, "locus": { "chromosome": "5", "start_pos": 22815011, "end_pos": 22745087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055629.1", "url": "https://www.ensembl.org/id/ENSGALT00010055629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033699.1", "url": "https://www.ensembl.org/id/ENSGALP00010033699.1" } ] } }, { "isoform_ac": "A0A8V0ZQE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11/entry#A0A8V0ZQE6-1", "sequence": { "sequence": "MLSPERLPGPEYLAQRHVLTYMEDAVSQLLENREDISQYGIARFFTEYFNSVRQGTHILFREFSFVQATPHNRASFLRTFWRCFRTVGKNGDLLTAQEYHCLLQLLCPDFPMELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLESVAAIYQDLLAGKNPNTVIVPTSSSGQHRQRQPPNDCNLPDGVEASLFYQCVESLCDRSKYSCPPSALVKEVLSTTQRLTFSGFLMTLAKDQGINRALGALPDKDLFLDPAMDQELEKLVAQVSGLSISAPTSSSGDTANFHGRNSPRINSPWKPLHHRRKIDAESEGSNEETDSSEN", "length": 330, "header": "tr|A0A8V0ZQE6-1|A0A8V0ZK11_CHICK Computationally mapped isoform of Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 OS=Gallus gallus OX=9031 GN=C11orf49 PE=3 SV=1 CANONICAL=A0A8V0ZK11-1" }, "locus": { "chromosome": "5", "start_pos": 22825726, "end_pos": 22745087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055633.1", "url": "https://www.ensembl.org/id/ENSGALT00010055633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033701.1", "url": "https://www.ensembl.org/id/ENSGALP00010033701.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 182, "start_aa": "Thr", "end_pos": 182, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr182", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423188", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423188", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MC77-1", "protein_name": "Centriolar satellite-associated tubulin polyglutamylase complex regulator 1", "gene_name": "CSTPP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSPERLALPDYEYLAQRHVLTYVEDAVCQLLENKEDISQYGIARFFTEYFNSVCQGTHILFREFSFIQATPHNRASFLRAFWRCFRTVGKNGDLLTMREYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLESVAAIYQDLLSGKNPNTVIVPTSSSGQHRHRPSTGEAGTPEGVEASLFYQCLENLCDRHKYSCPPPALVKEVLSNVQRLTFYGFLVALSKHHGINQALGALPDKGDLMHDPAMDEELERLLAQIPGLVTSVTAGPEASYLPPRTPPRVGSPWRPLHHARKVDGESDGSTEETDESET", "length": 331 }, "evidence": [ { "id": "A0A8V0ZK11", "url": "https://omabrowser.org/oma/group/A0A8V0ZK11/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A480UYS9-1", "protein_name": "Centriolar satellite-associated tubulin polyglutamylase complex regulator 1", "gene_name": "CSTPP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENKEDISQYGIARFFTEYFNSVCQGTHILFREFSFIQATPHNRASFLRAFWRCFRTVGKNGDLLTMKEYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLLAFQIQFYYSEFLESVAAIYQDLLSGKNPNTVIVPTSSSGQHRQRPALGEASTLEGVEASLFCQCLENLCDRHKYSCPPPALVKEVLSNVQRLTFYGFLVALSKHHGINQALGALPDKGDLMHDPAMDAELERLLAQIPGLVNPVTAGPEASCLPSRPPPRVGSPWRPLHHARKVDAESDGSTEETDESET", "length": 331 }, "evidence": [ { "id": "A0A8V0ZK11", "url": "https://omabrowser.org/oma/group/A0A8V0ZK11/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BHR8-1", "protein_name": "Centriolar satellite-associated tubulin polyglutamylase complex regulator 1", "gene_name": "Cstpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENREDISQYGIARFFTDYFNSVCQGTHILFREFSFIQATPHNRASFLRAFWRCFRTVGKNGDLLTMREYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLESVAAIYQDLLSGKNPNTVIVPTSSSGQHRQRPALGDAGMLDGVEASLFYQRLENLCDRHKYSCPPPALVKEILSNVQRLTFYGFLVALSKHHGINQALGALPDKGDLMHDPAMDEELERLLVQVPGLVNSITATSEASCLPSRTPPRVGSPWKPLHRSRKLDAESDGSTEETDESET", "length": 331 }, "evidence": [ { "id": "A0A8V0ZK11", "url": "https://omabrowser.org/oma/group/A0A8V0ZK11/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H6J7-1", "protein_name": "Centriolar satellite-associated tubulin polyglutamylase complex regulator 1", "gene_name": "CSTPP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENREDISQYGIARFFTEYFNSVCQGTHILFREFSFVQATPHNRVSFLRAFWRCFRTVGKNGDLLTMKEYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLDSVAAIYEDLLSGKNPNTVIVPTSSSGQHRQRPALGGAGTLEGVEASLFYQCLENLCDRHKYSCPPPALVKEALSNVQRLTFYGFLMALSKHRGINQALGALPDKGDLMHDPAMDEELERLLAQVPGLVNSVTASPEASCLPSRTPPRVGSPWRPLHHSRKVDGESDGSTEETDESET", "length": 331 }, "evidence": [ { "id": "A0A8V0ZK11", "url": "https://omabrowser.org/oma/group/A0A8V0ZK11/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of protein complex stability", "id": "GO:0061635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 182 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZL66-1", "uniprot_ac": "A0A8V0ZL66", "uniprot_id": "A0A8V0ZL66_CHICK", "mass": { "chemical_mass": 45308.0, "monoisotopic_mass": 45308.0 }, "refseq": {}, "gene_names": [ { "name": "ZFYVE27", "type": "recommended", "evidence": [ { "id": "A0A8V0ZL66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ] } ], "protein_names": [ { "name": "Zinc finger FYVE-type containing 27", "type": "synonym", "evidence": [ { "id": "A0A8V0ZL66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZFYVE27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66", "locus": { "chromosome": "6", "start_pos": 23088252, "end_pos": 23093511, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020595", "url": "https://www.ensembl.org/id/ENSGALG00010020595" } ] } } ], "crossref": [ { "id": "A0A8V0ZL66", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZL66", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15723", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15723", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z808", "url": "https://www.orthodb.org/?gene=A0A8V0Z808", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL66", "url": "https://www.orthodb.org/?gene=A0A8V0ZL66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14543", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14543", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14543:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14543:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z808", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z808", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z808-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z808-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQAAERDGVAGGLEAAAAVAATGGGEASSEPPSPPKAAAFDLLDLVRSYRRLELYLEPLRDAAEGVRSLLRWQRPLCSLLVCLGLNFLLLTLDQAAWYSVLALLVLLPALLGYLQETYRVRPSERELLRRKYHSVRREDLRRVQLSRQEALAQVKCFLIQLEGFLSGLCYNCEAVYRVLYWENPTVSSQFYGALLGSVCILYLLPLCWVMAILNSTLFLGNSQFYQVIKELKASVEQSLGTKPLESAPEPAKPLPTDAPPDRTPTPTSTEDLTPGSVEEAEEAEPDEEFKDAIEENQLLVMEDDEGSQCSADFDLSLPDNGFMSKNDVIRSKVSRLTERLRKRYPSNNFGTCTGCGATFSVLKKRVSLQSLQLASHTMAEVLCCVWLALAFLVARMAVLSHDPTVDDFS", "length": 409, "header": "tr|A0A8V0ZL66-1|A0A8V0ZL66_CHICK Isoform 1 of Zinc finger FYVE-type containing 27 OS=Gallus gallus OX=9031 GN=ZFYVE27 PE=4 SV=1 CANONICAL=A0A8V0ZL66-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z808-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66/entry#A0A8V0Z808-1", "sequence": { "sequence": "MRLRVCALSSGGSGPCALCSSASASTSSSSPSTKVCVHMCVCVCAGSAGLRPSADAVLLLAAAWYSVLALLVLLPALLGYLQETYRVRPSERELLRRKYHSVRREDLRRVQLSRQEALAQVKCFLIQLEGFLSGLCYNCEAVYRVLYWENPTVSSQFYGALLGSVCILYLLPLCWVMAILNSTLFLGNSQFYQVIKELKASVEQSLGTKPLESAPEPAKPLPTDAPPDRTPTPTSTEDLTPGSVEEAEEAEPDEEFKDAIEEDDEGSQCSADFDLSLPDNGFMSKNDVIRSKVSRLTERLRKRYPSNNFGTCTGCGATFSVLKKRRSCSNCGNSFCSRCCSFKVPKAVMGATAPEAQRETVFVCAQCNQMLIK", "length": 373, "header": "tr|A0A8V0Z808-1|A0A8V0ZL66_CHICK Computationally mapped isoform of Zinc finger FYVE-type containing 27 OS=Gallus gallus OX=9031 GN=ZFYVE27 PE=4 SV=1 CANONICAL=A0A8V0ZL66-1" }, "locus": { "chromosome": "6", "start_pos": 23093232, "end_pos": 23088994, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049713.1", "url": "https://www.ensembl.org/id/ENSGALT00010049713.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029374.1", "url": "https://www.ensembl.org/id/ENSGALP00010029374.1" } ] } }, { "isoform_ac": "A0A8V0ZL66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66/entry#A0A8V0ZL66-1", "sequence": { "sequence": "MQAAERDGVAGGLEAAAAVAATGGGEASSEPPSPPKAAAFDLLDLVRSYRRLELYLEPLRDAAEGVRSLLRWQRPLCSLLVCLGLNFLLLTLDQAAWYSVLALLVLLPALLGYLQETYRVRPSERELLRRKYHSVRREDLRRVQLSRQEALAQVKCFLIQLEGFLSGLCYNCEAVYRVLYWENPTVSSQFYGALLGSVCILYLLPLCWVMAILNSTLFLGNSQFYQVIKELKASVEQSLGTKPLESAPEPAKPLPTDAPPDRTPTPTSTEDLTPGSVEEAEEAEPDEEFKDAIEENQLLVMEDDEGSQCSADFDLSLPDNGFMSKNDVIRSKVSRLTERLRKRYPSNNFGTCTGCGATFSVLKKRVSLQSLQLASHTMAEVLCCVWLALAFLVARMAVLSHDPTVDDFS", "length": 409, "header": "tr|A0A8V0ZL66-1|A0A8V0ZL66_CHICK Isoform 1 of Zinc finger FYVE-type containing 27 OS=Gallus gallus OX=9031 GN=ZFYVE27 PE=4 SV=1 CANONICAL=A0A8V0ZL66-1" }, "locus": { "chromosome": "6", "start_pos": 23093413, "end_pos": 23090068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049702.1", "url": "https://www.ensembl.org/id/ENSGALT00010049702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029365.1", "url": "https://www.ensembl.org/id/ENSGALP00010029365.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "growth cone membrane", "id": "GO:0032584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032584", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network", "id": "GO:0071782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network formation", "id": "GO:0071787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" }, { "name": "positive regulation of axon extension", "id": "GO:0045773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045773", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" }, { "name": "neurotrophin TRK receptor signaling pathway", "id": "GO:0048011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048011", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMI4-1", "uniprot_ac": "A0A8V0ZMI4", "uniprot_id": "A0A8V0ZMI4_CHICK", "mass": { "chemical_mass": 23334.0, "monoisotopic_mass": 23334.0 }, "refseq": {}, "gene_names": [ { "name": "RAMP2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI4" } ] } ], "protein_names": [ { "name": "Receptor activity modifying protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAMP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI4", "locus": { "chromosome": "27", "start_pos": 5034178, "end_pos": 5028975, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022235", "url": "https://www.ensembl.org/id/ENSGALG00010022235" } ] } } ], "crossref": [ { "id": "A0A8V0ZMI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH54", "url": "https://www.orthodb.org/?gene=A0A8V0ZH54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMI4", "url": "https://www.orthodb.org/?gene=A0A8V0ZMI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPS9", "url": "https://www.orthodb.org/?gene=A0A8V0ZPS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13149:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13149:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05871", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05871", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZH54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPCAQMGSGHLSRGLLLLCALLGHQFCHVGATAEGFRQEARTSPPVSAYNHTGKLVAEMIQQMKSSMVWMRLCYFVPCKPCSKSTRLKSSHWMMAEASSSSDGSPLPASLWRLEHFLAWFQAVAQAAAYLELLGVKRICEAFQRHDFLSCCCFPILVNAVDGHSGGWSGTAAKGFSSQLPAACLGSIAPTAWLSEVKANTQNALLLLWHRRPH", "length": 214, "header": "tr|A0A8V0ZMI4-1|A0A8V0ZMI4_CHICK Isoform 1 of Receptor activity modifying protein 2 OS=Gallus gallus OX=9031 GN=RAMP2 PE=4 SV=1 CANONICAL=A0A8V0ZMI4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZH54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI4/entry#A0A8V0ZH54-1", "sequence": { "sequence": "MSFSWPWQYSFPPFFTLQPNGETRQKQLAAWCALALAYSRRQRLPAMTLREAQDSPLFANRRLQSILWARSGPLRSPLPPSLVGCLLNQLSREAAARGHPGGAGGAAQEREPGVVRQEQNQFSDNVEKTRGMGKAHLSVSKNGLTNSVFTLYELISGDDTANEEFHGLDEAMLLRALQALQQEHKAEIITLDDGRGVKFF", "length": 200, "header": "tr|A0A8V0ZH54-1|A0A8V0ZMI4_CHICK Computationally mapped isoform of Receptor activity modifying protein 2 OS=Gallus gallus OX=9031 GN=RAMP2 PE=4 SV=1 CANONICAL=A0A8V0ZMI4-1" }, "locus": { "chromosome": "27", "start_pos": 5032837, "end_pos": 5030896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054113.1", "url": "https://www.ensembl.org/id/ENSGALT00010054113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032644.1", "url": "https://www.ensembl.org/id/ENSGALP00010032644.1" } ] } }, { "isoform_ac": "A0A8V0ZMI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI4/entry#A0A8V0ZMI4-1", "sequence": { "sequence": "MAPCAQMGSGHLSRGLLLLCALLGHQFCHVGATAEGFRQEARTSPPVSAYNHTGKLVAEMIQQMKSSMVWMRLCYFVPCKPCSKSTRLKSSHWMMAEASSSSDGSPLPASLWRLEHFLAWFQAVAQAAAYLELLGVKRICEAFQRHDFLSCCCFPILVNAVDGHSGGWSGTAAKGFSSQLPAACLGSIAPTAWLSEVKANTQNALLLLWHRRPH", "length": 214, "header": "tr|A0A8V0ZMI4-1|A0A8V0ZMI4_CHICK Isoform 1 of Receptor activity modifying protein 2 OS=Gallus gallus OX=9031 GN=RAMP2 PE=4 SV=1 CANONICAL=A0A8V0ZMI4-1" }, "locus": { "chromosome": "27", "start_pos": 5033174, "end_pos": 5029066, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054131.1", "url": "https://www.ensembl.org/id/ENSGALT00010054131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032662.1", "url": "https://www.ensembl.org/id/ENSGALP00010032662.1" } ] } }, { "isoform_ac": "A0A8V0ZPS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI4/entry#A0A8V0ZPS9-1", "sequence": { "sequence": "MSFSWPWQYSFPPFFTLQPNGETRQKQLAAWCALALAYSRRQRLPAMTLREAQDSPLFANRRLQRKLPPEAIQVVLEELRKNGNLEWLDKNKTSFLIMWRRPEEWGKLIYQWVSKNGLTNSVFTLYELISGDDTANEAFQRHDFLSCCCFPILVNAVDGHSGGWSGTAAKGFSSQLPAACLGSIAPTAWLSEVKANTQNALLLLWHRRPH", "length": 210, "header": "tr|A0A8V0ZPS9-1|A0A8V0ZPS9_CHICK Computationally mapped isoform of Vacuolar protein-sorting-associated protein 25 OS=Gallus gallus OX=9031 GN=RAMP2 PE=3 SV=1 CANONICAL=A0A8V0ZMI4-1" }, "locus": { "chromosome": "27", "start_pos": 5033174, "end_pos": 5030896, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054122.1", "url": "https://www.ensembl.org/id/ENSGALT00010054122.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032653.1", "url": "https://www.ensembl.org/id/ENSGALP00010032653.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKL6-1", "uniprot_ac": "A0A8V0ZKL6", "uniprot_id": "A0A8V0ZKL6_CHICK", "mass": { "chemical_mass": 132766.0, "monoisotopic_mass": 132766.0 }, "refseq": { "ac": "XP_004942977", "name": "uncharacterized protein ARHGEF1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942977" }, "gene_names": [ { "name": "ARHGEF1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6" } ] }, { "name": "ARHGEF1", "type": "synonym", "evidence": [ { "id": "XP_004942977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942977" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein ARHGEF1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004942977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942977" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004942977.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942977" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGEF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZKL6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKL6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026460", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026460", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424241", "url": "https://www.ncbi.nlm.nih.gov/gene/424241", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051480", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051480", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424241", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424241", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCKGRLY", "url": "https://omabrowser.org/oma/group/RCKGRLY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UDE9", "url": "https://www.orthodb.org/?gene=A0A3Q2UDE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AN37", "url": "https://www.orthodb.org/?gene=A0A3Q3AN37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF55", "url": "https://www.orthodb.org/?gene=A0A8V0ZF55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKL6", "url": "https://www.orthodb.org/?gene=A0A8V0ZKL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSZ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZSZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46006:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46006:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942977", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942977", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2UDE9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UDE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UDE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UDE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AN37", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AN37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AN37-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AN37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTYINVDERQEHCRVILSCQNNQLCAQHGLKEFSVSSMHPLKNLDTHVFSGDFHTVHSCHTGKALLANPVEKRMYRSVENLHWATVADSGLYSHCRSLDNEIIFRYRGTRQWSEGCVDVAPIRSTLDSLRNLSLRPKQTSQSAQNVLLPPYVKVPQWLFPSAEDRALREDAKKELKEKLRLHSNKVAEPSKPVRPQAALTDLAAQEFSECQMCQQYKNGCAVSCCTVLVEHTARRHSLTGRQRLCVAHRIISPEDIKQEAQRRLRLHRQNSSPSLPFQHAEESHEMEKSRTAESLERLTGEIDVKETLGQSRKSHCKGRLYIPSFEEFKQMRSKEANSSAGSSETTKHLNKRLLANQPLDEESNKNICPEGLGTEAVNEAAITAEDDDNVFQENHTSAGFSQYPVTWDGFRINSPEVKDRTVQSSSLDISPVPICSSPIPRSPLQAVAVHRAGQEIFSGEQQKGETRKLNDVLHLAGQSLASEAQSSCCSSLLLEGADLSSYGAKLQKMKDEFIGSALELIKKSCNAETAAKPPSEGQCDLKEDDQPPPEDSQQATAMSMATESWEDKTSNEKPSDTQPAGNTSSPSCRRSSSDIVHESTDGAKAQRECRLRPHFSDPMPTDSVKRKQLELKIAAAARQHAQKRRQERDYGPVVAKANLGHGSSFDETRRAPRGSLRSRHHWSNVSSLSTDSGIVGVNDVRDDLDPSEATRTKSAEVERADSGISQMSARKWRNRASETLSSLQAWEAHRPCTDCGERDLPVETDMQNCNQRRADLCEKCRKRRTERKESVLEFVNTEASYGEDLRIIKEEFYLPMQAAGLLSQEQLLGIFSNIQELIDLNESFLEILQEEIDQAFDQGDDDLMTVCIGEIFLEFVNMLPAFQTYCLQQSSSVNMLNALEKEKELLRIFLNVSQNDNTALRRMNLRSFLMAPLQRVTKYPLLLSRIIKATTEYHPDHGSLREAKSRIESHLEHINMKTKQEGNTWTLRSFRQDSKKKREVINIEMRETALKTVGWLREETRFVMEGSLQLAQPPDGQWVKKGSKTLKFQNMQVLLLVNMKRVSESSLESAEPGPVKDAVLVLIRDKNNGKFHLLREPLRLSNCIVSTDPDCDDTFELIEIRREAFVFRDSDRARTHHWFRQIRRYSRELGSWKKRRNALPNIMISTPHTRP", "length": 1171, "header": "tr|A0A8V0ZKL6-1|A0A8V0ZKL6_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=ARHGEF1 PE=4 SV=1 CANONICAL=A0A8V0ZKL6-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UDE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6/entry#A0A3Q2UDE9-1", "sequence": { "sequence": "MITESPDPHVSLLSPVGSSTAVKKGELQPHHEKTGCNAETAAKPPSEGQCDLKEDDQPPPEDSQQATAMSMATESWEDKTSNEKPSDTQPAGNTSSPSCRRSSSDIVHESTDGAKAQRECRLRPHFSDPMPTDSVKRKQLELKIAAAARQHAQKRRQERDYGPVVAKANLGHGSSFDETRRAPRGSLRSRHHWSNVSSLSTDSGIVGVNDVRDDLDPSEATRTKSAEVERADSGISQMSARKWRNRASETLSSLQAWEAHRPCTDCGERDLPVETDMQNCNQRRADLCEKCRKRRTERKESVLEFVNTEASYGEDLRIIKEEFYLPMQAAGLLSQEQLLGIFSNIQELIDLNESFLEILQEEIDQAFDQGDDDLMTVCIGEIFLEFVNMLPAFQTYCLQQSSSVNMLNALEKEKELLRIFLNVSQNDNTALRRMNLRSFLMAPLQRVTKYPLLLSRIIKATTEYHPDHGSLREAKSRIESHLEHINMKTKQEGNTWTLRSFRQDSKKKREVINIEMRETALKTVGWLREETRFVMEGSLQLAQPPDGQWVKKGSKTLKFQNMQVLLLVNMKRVSESSLESAEPGPVKDAVLVLIRDKNNGKFHLLREPLRLSNCIVSTDPDCDDTFELIEIRREAFVFRDSDRARTHHWFRQIRRYSRELGSWKKRRNALPNIMISTPHTRP", "length": 682, "header": "tr|A0A3Q2UDE9-1|A0A8V0ZKL6_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=ARHGEF1 PE=4 SV=1 CANONICAL=A0A8V0ZKL6-1" }, "locus": { "chromosome": "7", "start_pos": 25891731, "end_pos": 25877830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053021.1", "url": "https://www.ensembl.org/id/ENSGALT00010053021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031927.1", "url": "https://www.ensembl.org/id/ENSGALP00010031927.1" } ] } }, { "isoform_ac": "A0A3Q3AN37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6/entry#A0A3Q3AN37-1", "sequence": { "sequence": "MSRLCLQEPLLHKLSCNAETAAKPPSEGQCDLKEDDQPPPEDSQQATAMSMATESWEDKTSNEKPSDTQPAGNTSSPSCRRSSSDIVHESTDGAKAQRECRLRPHFSDPMPTDSVKRKQLELKIAAAARQHAQKRRQERDYGPVVAKANLGHGSSFDETRRAPRGSLRSRHHWSNVSSLSTDSGIVGVNDVRDDLDPSEATRTKSAEVERADSGISQMSARKWRNRASETLSSLQAWEAHRPCTDCGERDLPVETDMQNCNQRRADLCEKCRKRRTERKESVLEFVNTEASYGEDLRIIKEEFYLPMQAAGLLSQEQLLGIFSNIQELIDLNESFLEILQEEIDQAFDQGDDDLMTVCIGEIFLEFVNMLPAFQTYCLQQSSSVNMLNALEKEKELLRIFLNVSQNDNTALRRMNLRSFLMAPLQRVTKYPLLLSRIIKATTEYHPDHGSLREAKSRIESHLEHINMKTKQEGNTWTLRSFRQDSKKKREVINIEMRETALKTVGWLREETRFVMEGSLQLAQPPDGQWVKKGSKTLKFQNMQVLLLVNMKRVSESSLESAEPGPVKDAVLVLIRDKNNGKFHLLREPLRLSNCIVSTDPDCDDTFELIEIRREAFVFRDSDRARTHHWFRQIRRYSRELGSWKKRRNALPNIMISTPHTRP", "length": 662, "header": "tr|A0A3Q3AN37-1|A0A8V0ZKL6_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=ARHGEF1 PE=4 SV=1 CANONICAL=A0A8V0ZKL6-1" }, "locus": { "chromosome": "7", "start_pos": 25895557, "end_pos": 25877830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053027.1", "url": "https://www.ensembl.org/id/ENSGALT00010053027.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031933.1", "url": "https://www.ensembl.org/id/ENSGALP00010031933.1" } ] } }, { "isoform_ac": "A0A8V0ZF55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6/entry#A0A8V0ZF55-1", "sequence": { "sequence": "METFPCSCNAETAAKPPSEGQCDLKEDDQPPPEDSQQATAMSMATESWEDKTSNEKPSDTQPAGNTSSPSCRRSSSDIVHESTDGAKAQRECRLRPHFSDPMPTDSVKRKQLELKIAAAARQHAQKRRQERDYGPVVAKANLGHGSSFDETRRAPRGSLRSRHHWSNVSSLSTDSGIVGVNDVRDDLDPSEATRTKSAEVERADSGISQMSARKWRNRASETLSSLQAWEAHRPCTDCGERDLPVETDMQNCNQRRADLCEKCRKRRTERKESVLEFVNTEASYGEDLRIIKEEFYLPMQAAGLLSQEQLLGIFSNIQELIDLNESFLEILQEEIDQAFDQGDDDLMTVCIGEIFLEFVNMLPAFQTYCLQQSSSVNMLNALEKEKELLRIFLNVSQNDNTALRRMNLRSFLMAPLQRVTKYPLLLSRIIKATTEYHPDHGSLREAKSRIESHLEHINMKTKQEGNTWTLRSFRQDSKKKREVINIEMRETALKTVGWLREETRFVMEGSLQLAQPPDGQWVKKGSKTLKFQNMQVLLLVNMKRVSESSLESAEPGPVKDAVLVLIRDKNNGKFHLLREPLRLSNCIVSTDPDCDDTFELIEIRREAFVFRDSDRARTHHWFRQIRRYSRELGSWKKRRNALPNIMISTPHTRP", "length": 654, "header": "tr|A0A8V0ZF55-1|A0A8V0ZKL6_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=ARHGEF1 PE=4 SV=1 CANONICAL=A0A8V0ZKL6-1" }, "locus": { "chromosome": "7", "start_pos": 25887596, "end_pos": 25877830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053019.1", "url": "https://www.ensembl.org/id/ENSGALT00010053019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031925.1", "url": "https://www.ensembl.org/id/ENSGALP00010031925.1" } ] } }, { "isoform_ac": "A0A8V0ZKL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6/entry#A0A8V0ZKL6-1", "sequence": { "sequence": "MTYINVDERQEHCRVILSCQNNQLCAQHGLKEFSVSSMHPLKNLDTHVFSGDFHTVHSCHTGKALLANPVEKRMYRSVENLHWATVADSGLYSHCRSLDNEIIFRYRGTRQWSEGCVDVAPIRSTLDSLRNLSLRPKQTSQSAQNVLLPPYVKVPQWLFPSAEDRALREDAKKELKEKLRLHSNKVAEPSKPVRPQAALTDLAAQEFSECQMCQQYKNGCAVSCCTVLVEHTARRHSLTGRQRLCVAHRIISPEDIKQEAQRRLRLHRQNSSPSLPFQHAEESHEMEKSRTAESLERLTGEIDVKETLGQSRKSHCKGRLYIPSFEEFKQMRSKEANSSAGSSETTKHLNKRLLANQPLDEESNKNICPEGLGTEAVNEAAITAEDDDNVFQENHTSAGFSQYPVTWDGFRINSPEVKDRTVQSSSLDISPVPICSSPIPRSPLQAVAVHRAGQEIFSGEQQKGETRKLNDVLHLAGQSLASEAQSSCCSSLLLEGADLSSYGAKLQKMKDEFIGSALELIKKSCNAETAAKPPSEGQCDLKEDDQPPPEDSQQATAMSMATESWEDKTSNEKPSDTQPAGNTSSPSCRRSSSDIVHESTDGAKAQRECRLRPHFSDPMPTDSVKRKQLELKIAAAARQHAQKRRQERDYGPVVAKANLGHGSSFDETRRAPRGSLRSRHHWSNVSSLSTDSGIVGVNDVRDDLDPSEATRTKSAEVERADSGISQMSARKWRNRASETLSSLQAWEAHRPCTDCGERDLPVETDMQNCNQRRADLCEKCRKRRTERKESVLEFVNTEASYGEDLRIIKEEFYLPMQAAGLLSQEQLLGIFSNIQELIDLNESFLEILQEEIDQAFDQGDDDLMTVCIGEIFLEFVNMLPAFQTYCLQQSSSVNMLNALEKEKELLRIFLNVSQNDNTALRRMNLRSFLMAPLQRVTKYPLLLSRIIKATTEYHPDHGSLREAKSRIESHLEHINMKTKQEGNTWTLRSFRQDSKKKREVINIEMRETALKTVGWLREETRFVMEGSLQLAQPPDGQWVKKGSKTLKFQNMQVLLLVNMKRVSESSLESAEPGPVKDAVLVLIRDKNNGKFHLLREPLRLSNCIVSTDPDCDDTFELIEIRREAFVFRDSDRARTHHWFRQIRRYSRELGSWKKRRNALPNIMISTPHTRP", "length": 1171, "header": "tr|A0A8V0ZKL6-1|A0A8V0ZKL6_CHICK Isoform 1 of Rho guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=ARHGEF1 PE=4 SV=1 CANONICAL=A0A8V0ZKL6-1" }, "locus": { "chromosome": "7", "start_pos": 25889915, "end_pos": 25877830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053031.1", "url": "https://www.ensembl.org/id/ENSGALT00010053031.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031937.1", "url": "https://www.ensembl.org/id/ENSGALP00010031937.1" } ] } }, { "isoform_ac": "A0A8V0ZSZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6/entry#A0A8V0ZSZ4-1", "sequence": { "sequence": "MHNKGERGGAARGLCSCNAETAAKPPSEGQCDLKEDDQPPPEDSQQATAMSMATESWEDKTSNEKPSDTQPAGNTSSPSCRRSSSDIVHESTDGAKAQRECRLRPHFSDPMPTDSVKRKQLELKIAAAARQHAQKRRQERDYGPVVAKANLGHGSSFDETRRAPRGSLRSRHHWSNVSSLSTDSGIVGVNDVRDDLDPSEATRTKSAEVERADSGISQMSARKWRNRASETLSSLQAWEAHRPCTDCGERDLPVETDMQNCNQRRADLCEKCRKRRTERKESVLEFVNTEASYGEDLRIIKEEFYLPMQAAGLLSQEQLLGIFSNIQELIDLNESFLEILQEEIDQAFDQGDDDLMTVCIGEIFLEFVNMLPAFQTYCLQQSSSVNMLNALEKEKELLRIFLNVSQNDNTALRRMNLRSFLMAPLQRVTKYPLLLSRIIKATTEYHPDHGSLREAKSRIESHLEHINMKTKQEGNTWTLRSFRQDSKKKREVINIEMRETALKTVGWLREETRFVMEGSLQLAQPPDGQWVKKGSKTLKFQNMQVLLLVNMKRVSESSLESAEPGPVKDAVLVLIRDKNNGKFHLLREPLRLSNCIVSTDPDCDDTFELIEIRREAFVFRDSDRARTHHWFRQIRRYSRELGSWKKRRNALPNIMISTPHTRP", "length": 663, "header": "tr|A0A8V0ZSZ4-1|A0A8V0ZKL6_CHICK Computationally mapped isoform of Rho guanine nucleotide exchange factor 1 OS=Gallus gallus OX=9031 GN=ARHGEF1 PE=4 SV=1 CANONICAL=A0A8V0ZKL6-1" }, "locus": { "chromosome": "7", "start_pos": 25915329, "end_pos": 25877830, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053025.1", "url": "https://www.ensembl.org/id/ENSGALT00010053025.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031931.1", "url": "https://www.ensembl.org/id/ENSGALP00010031931.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 621, "start_aa": "Thr", "end_pos": 621, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr621", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424241", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424241", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BFM6-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "arhgef49", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAALSVAMPDVKAPQCDYSPAGSPAGCSMDLSMDLSVLSSPLSAFPHHGVPSFPAQGVTPGHCNNNNGLLSNLGLYCSTSSMHPLKQPAGQSGYSTLRFPQGCINTGGTRLYRSLENLHWAAVSDPNAYPYRTVDSEFILHCTSRSHWYDGASQEQQVYGLMPSPDGMAIYGRRGVLKKDIPLFPQWLLPAVEDWGMNGNARKGLRDKLRLQSTRVAEPIKPVRPQPVLGNAPSLMHQDVAVQPGLAFLQKNGQRELSARRITSPEEIKQEAMRRLQLRRQRSTPNLALTCRQESSALSKAQTAELICTNSAQSTPERKRPPMGRLHIPTFEEFKRMRQRESSKNHSSSEMESCDRPSEDTQNPERTANNVRTTLDSAGGPSGGEMSELISTTVVPGGPICTGPVARSPLHPQAAAGKEEETKGPAGPGATDVAVLPFPPRRESGDVPSSCCQAILLDGTDLSSYGAKIYKMRDGFLGSALDLIKKSCSAEIAAETPVRLSREPDDVTGITQPCHQSACVAMTTQACGEEACTEPTGRRGKADTECVSGPGCRRSSSDAAYELAESVKAQRECRLRPHYSDPMPADATKRKQLEMKIAAAARLHIHRRDRDTAAGTARGRSEPRGEERSRGLGVRRSAQHRWSTVSSLSADSGVVGWSDEREDEEEPRRARHSAGAEVERVDSGIGHGLARSWRRPLPSLRTWDVQQPCPDCGHKEGAHGEGMCERCSKLRTERKEAILEFLNTESSYGEDLRIIKEEFYCPMQSAGLLTAEQLAVVFSNVQELIDVNEKFTEHLQDSIDQAFDQGDEDLQAVCIGEIFLEFVNMLPAFQTYCLQQSTSVNMLNTLEKEKELLRIFLDVSQNDNTALRRMNLRSFLMAPLQRVTKYPLLLSRISKATNECHPDYPRLKEAKSRVESHLEHINMKTKQEGTATWSLRSFRRDSRKNREVINIEMRELSMKMVGWARESTRFIMEGPLQLAQPADGQWLKKGSKSLKFQNVQSLLMVRTLRATDAVPDGSLESSEAVQDGVLVLIKDKSSGKFTVLREPIRLANCVVSVDPDCEDTFEVLDIRREAFVFRASDKPRTQQWFRQVKRYVCDLGSWRKRRNALPNIMINTSQSRS", "length": 1121 }, "evidence": [ { "id": "A0A8V0ZKL6", "url": "https://omabrowser.org/oma/group/A0A8V0ZKL6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 684, "end_pos": 686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 841, "end_pos": 843, "annotation": "n_glycosylation_sequon" }, { "start_pos": 911, "end_pos": 913, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL6" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 786, "end_pos": 977, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 621 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 684, "end_pos": 686 }, { "start_pos": 841, "end_pos": 843 }, { "start_pos": 911, "end_pos": 913 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMS7-1", "uniprot_ac": "A0A8V0ZMS7", "uniprot_id": "A0A8V0ZMS7_CHICK", "mass": { "chemical_mass": 28816.0, "monoisotopic_mass": 28816.0 }, "refseq": {}, "gene_names": [ { "name": "NRN1L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7" } ] } ], "protein_names": [ { "name": "Neuritin 1 like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NRN1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZMS7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000050750", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000050750", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100858970", "url": "https://www.ncbi.nlm.nih.gov/gene/100858970", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HACASQV", "url": "https://omabrowser.org/oma/group/HACASQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AUX4", "url": "https://www.orthodb.org/?gene=A0A3Q3AUX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMS7", "url": "https://www.orthodb.org/?gene=A0A8V0ZMS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15902:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15902:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15056", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15056", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-163125", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q3AUX4", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AUX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AUX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AUX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCGCGRLLGVVCPLLLLLLLHVAPQNHKGWKRPLRSPNPPSLCPTSPPLQTQRFPCFAACMLGPRTRCRLRWVLPRREPSGCYLVVGAQLHPSAPRSRRSGAHQHGREVQHHLQGLRWLPHQPGGQHGAERAAAAGRGGGGGWPGGAGVGHHLQVSGSRPRPPMLGAATAASLMPTPTCRSWDEFHACASGVLSRCPEEAAAIWESLRQESRKIQFQGNLQELCSARGRLASAQGSPPAETNQATLRGSAPPGHPGILPLLALVLLGAWA", "length": 271, "header": "tr|A0A8V0ZMS7-1|A0A8V0ZMS7_CHICK Isoform 1 of Neuritin 1 like OS=Gallus gallus OX=9031 GN=NRN1L PE=3 SV=1 CANONICAL=A0A8V0ZMS7-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AUX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7/entry#A0A3Q3AUX4-1", "sequence": { "sequence": "MGCGCGRLLGVVCPLLLLLLLHVAVAQEPISTAGKCNTIYKGFAGCLISLGDSMAQSVRQQRDEEEEEGGQEAQELDTICRSWDEFHACASGVLSRCPEEAAAIWESLRQESRKIQFQGNLQELCSARGRLASAQGSPPAETNQATLRGSAPPGHPGILPLLALVLLGAWA", "length": 171, "header": "tr|A0A3Q3AUX4-1|A0A8V0ZMS7_CHICK Computationally mapped isoform of Neuritin 1 like OS=Gallus gallus OX=9031 GN=NRN1L PE=3 SV=1 CANONICAL=A0A8V0ZMS7-1" }, "locus": { "chromosome": "11", "start_pos": 973841, "end_pos": 972289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053303.1", "url": "https://www.ensembl.org/id/ENSGALT00010053303.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032125.1", "url": "https://www.ensembl.org/id/ENSGALP00010032125.1" } ] } }, { "isoform_ac": "A0A8V0ZMS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7/entry#A0A8V0ZMS7-1", "sequence": { "sequence": "MGCGCGRLLGVVCPLLLLLLLHVAPQNHKGWKRPLRSPNPPSLCPTSPPLQTQRFPCFAACMLGPRTRCRLRWVLPRREPSGCYLVVGAQLHPSAPRSRRSGAHQHGREVQHHLQGLRWLPHQPGGQHGAERAAAAGRGGGGGWPGGAGVGHHLQVSGSRPRPPMLGAATAASLMPTPTCRSWDEFHACASGVLSRCPEEAAAIWESLRQESRKIQFQGNLQELCSARGRLASAQGSPPAETNQATLRGSAPPGHPGILPLLALVLLGAWA", "length": 271, "header": "tr|A0A8V0ZMS7-1|A0A8V0ZMS7_CHICK Isoform 1 of Neuritin 1 like OS=Gallus gallus OX=9031 GN=NRN1L PE=3 SV=1 CANONICAL=A0A8V0ZMS7-1" }, "locus": { "chromosome": "11", "start_pos": 973841, "end_pos": 972289, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053300.1", "url": "https://www.ensembl.org/id/ENSGALT00010053300.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032123.1", "url": "https://www.ensembl.org/id/ENSGALP00010032123.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-163125", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-163125", "resource": "Reactome", "description": "Post-translational modification: synthesis of GPI-anchored proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LUX9-1", "protein_name": "Neuritin-like protein", "gene_name": "Nrn1l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MMCYCWRCCCQRLPCALTLLLLLPLAMASEGPNRCDSIYQGFAECLIRLGESMGRGLELQTVCRSWNDFHACASRVLSGCPEEAAAVWESLQQEARRAPHPDNLHILCGAPVSVREMVAGPETNQETLRATAPALTPAPTPALLAAALALACLLGPLA", "length": 158 }, "evidence": [ { "id": "A0A8V0ZMS7", "url": "https://omabrowser.org/oma/group/A0A8V0ZMS7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q496H8-1", "protein_name": "Neuritin-like protein", "gene_name": "NRN1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMRCCRRRCCCRQPPHALRPLLLLPLVLLPPLAAAAAGPNRCDTIYQGFAECLIRLGDSMGRGGELETICRSWNDFHACASQVLSGCPEEAAAVWESLQQEARQAPRPNNLHTLCGAPVHVRERGTGSETNQETLRATAPALPMAPAPPLLAAALALAYLLRPLA", "length": 165 }, "evidence": [ { "id": "A0A8V0ZMS7", "url": "https://omabrowser.org/oma/group/A0A8V0ZMS7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C4W3-1", "protein_name": "Neuritin-like protein", "gene_name": "Nrn1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMCNCCHCHWRRRCQRLPCALTLLLLLPLAVASEGPNRCDTIYQGFAECLIRLGDGMGRGGELQTVCRSWNDFHACASRVLSGCPEEAAAVWESLQQEARRAPHPDNLHILCGAPVSVRERIAGPETNQETLRATAPALAPAPAPVLLAAALALACLLGPLA", "length": 162 }, "evidence": [ { "id": "A0A8V0ZMS7", "url": "https://omabrowser.org/oma/group/A0A8V0ZMS7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7" } ], "pmid": "" }, { "name": "neuron projection extension", "id": "GO:1990138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990138", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMR8-1", "uniprot_ac": "A0A8V0ZMR8", "uniprot_id": "A0A8V0ZMR8_CHICK", "mass": { "chemical_mass": 99618.0, "monoisotopic_mass": 99618.0 }, "refseq": { "ac": "XP_040534138", "name": "ecotropic viral integration site 5 protein homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534138" }, "gene_names": [ { "name": "EVI5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8" } ] }, { "name": "EVI5", "type": "synonym", "evidence": [ { "id": "XP_040534138", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534138" } ] } ], "protein_names": [ { "name": "Ecotropic viral integration site 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8/entry#names_and_taxonomy" } ] }, { "name": "ecotropic viral integration site 5 protein homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040534138", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534138" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052580.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040534138.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040534138", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534138" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EVI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8", "locus": { "chromosome": "8", "start_pos": 13861980, "end_pos": 13792057, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021817", "url": "https://www.ensembl.org/id/ENSGALG00010021817" } ] } } ], "crossref": [ { "id": "A0A8V0ZMR8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMR8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029582", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029582", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424500", "url": "https://www.ncbi.nlm.nih.gov/gene/424500", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3AVD8", "url": "https://www.orthodb.org/?gene=A0A3Q3AVD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFA4", "url": "https://www.orthodb.org/?gene=A0A8V0ZFA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFG8", "url": "https://www.orthodb.org/?gene=A0A8V0ZFG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKQ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZKQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZME9", "url": "https://www.orthodb.org/?gene=A0A8V0ZME9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMR8", "url": "https://www.orthodb.org/?gene=A0A8V0ZMR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT41", "url": "https://www.orthodb.org/?gene=A0A8V0ZT41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040534138", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534138", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3AVD8", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AVD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AVD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AVD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZME9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZME9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAGTVAAVQKGSELAEVATDKVAGKLSSTLSWVKNTVSHTVSQMASQVASPSASLHTTSSSTTLSTPALSPSSPAQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHDFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELYVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQTNQAELLQLDMEGMLQHFQKVIPHQFDSGPDKLIQASYQVKYNAKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQSDEANTKLEQAESTIRELQQQQQWHKCSSRYSEDFVLQLEKELVQARLSEAESHCALKEMQDKVLEMEKRNSSLPDEENVARLQEELIAVKLREAEALMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPRKNTVNELQDELMTVRLREAETQAELKETKQRMMEMETQSQINNNHLRRAELEVTSLQEKVQYLTAQNKGLLAQLNEAKRRQAEIECKSKEEVMAARLREADSIAAVAELQQHIAELEIQKEEGKIQGQLNKSDSNQYIRELKDQIAELHHEIKCLKGQKDFSDQPTFDGIHIVNHFTGDDESFHSSDEDFITNSIQESGVNFHLHRRTGQMVLDRTVVDSSDSENEESTLQTGNLDKMVSKQRRMESYSTTV", "length": 867, "header": "tr|A0A8V0ZMR8-1|A0A8V0ZMR8_CHICK Isoform 1 of Ecotropic viral integration site 5 OS=Gallus gallus OX=9031 GN=EVI5 PE=4 SV=1 CANONICAL=A0A8V0ZMR8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AVD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8/entry#A0A3Q3AVD8-1", "sequence": { "sequence": "MNLSRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHDFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELYVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQTNQAELLQLDMEGMLQHFQKVIPHQFDSGPDKLIQASYQVKYNAKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQSDEANTKLEQAESTIRELQQQQQWHKCSSRYSEDFVLQLEKELVQARLSEAESHCALKEMQDKVLEMEKRNSSLPDEENVARLQEELIAVKLREAEALMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPRKNTVNELQDELMTVRLREAETQAELKETKQRMMEMETQSQINNNHLRRAELEVTSLQEKVQYLTAQNKGLLAQLNEAKRRQAEIECKSKEEVMAARLREADSIAAVAELQQHIAELEIQKEEGKIQGQLNKSDSNQYIRELKDQIAELHHEIKCLKGQKDFSDQPTFDGIHIVNHFTGDDESFHSSDEDFITNSIQESGVNFHLHRRTGQMVLDRTVVDSSDSENEESTLQTGNLDKMVSKQRRMESYSTTV", "length": 778, "header": "tr|A0A3Q3AVD8-1|A0A8V0ZMR8_CHICK Computationally mapped isoform of Ecotropic viral integration site 5 OS=Gallus gallus OX=9031 GN=EVI5 PE=4 SV=1 CANONICAL=A0A8V0ZMR8-1" }, "locus": { "chromosome": "8", "start_pos": 13861022, "end_pos": 13801894, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053084.1", "url": "https://www.ensembl.org/id/ENSGALT00010053084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031973.1", "url": "https://www.ensembl.org/id/ENSGALP00010031973.1" } ] } }, { "isoform_ac": "A0A8V0ZFA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8/entry#A0A8V0ZFA4-1", "sequence": { "sequence": "MASQVASPSASLHTTSSSTTLSTPALSPSSPAQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHDFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELYVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQTNQAELLQLDMEGMLQHFQKVIPHQFDSGPDKLIQASYQVKYNAKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKHKCSSRYSEDFVLQLEKELVQARLSEAESHCALKEMQDKVLEMEKRNSSLPDEENVARLQEELIAVKLREAEALMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPRKNTVNELQDELMTVRLREAETQAELKETKQRMMEMETQSQINNNHLRRAELEVTSLQEKVQYLTAQNKGLLAQLNEAKRRQAEIECKSKEEVMAARLREADSIAAVAELQQHIAELEIQKEEGKIQGQLNKSDSNQYIRELKDQIAELHHEIKCLKGQKDFSDQPTFDGIHIVNHFTGDDESFHSSDEDFITNSIQESGVNFHLHRRTGQMVLDRTVVDSSDSENEESTLQTGNLDKMVSKQRRMESYSTTV", "length": 763, "header": "tr|A0A8V0ZFA4-1|A0A8V0ZMR8_CHICK Computationally mapped isoform of Ecotropic viral integration site 5 OS=Gallus gallus OX=9031 GN=EVI5 PE=4 SV=1 CANONICAL=A0A8V0ZMR8-1" }, "locus": { "chromosome": "8", "start_pos": 13861022, "end_pos": 13799821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053088.1", "url": "https://www.ensembl.org/id/ENSGALT00010053088.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031976.1", "url": "https://www.ensembl.org/id/ENSGALP00010031976.1" } ] } }, { "isoform_ac": "A0A8V0ZFG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8/entry#A0A8V0ZFG8-1", "sequence": { "sequence": "MLAGTVAAVQKGSELAEVATDKVAGKLSSTLSWVKNTVSHTVSQMASQVASPSASLHTTSSSTTLSTPALSPSSPAQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHDFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELYVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQTNQAELLQLDMEGMLQHFQKVIPHQFDSGPDKLIQASYQVKYNAKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKHKCSSRYSEDFVLQLEKELVQARLSEAESHCALKEMQDKVLEMEKRNSSLPDEENVARLQEELIAVKLREAEALMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPRKNTVNELQDELMTVRLREAETQAELKETKQRMMEMETQSQINNNHLRRAELEVTSLQEKVQYLTAQNKGLLAQLNEAKRRQAEIECKSKEEVMAARLREADSIAAVAELQQHIAELEIQIKCLKGQKDFSDQPTFDGIHIVNHFTGDDESFHSSDEDFITNSIQESGVNFHLHRRTGQMVLDRTVVDSSDSENEESTLQTGNLDKMVSKQRRMESYSTTV", "length": 775, "header": "tr|A0A8V0ZFG8-1|A0A8V0ZMR8_CHICK Computationally mapped isoform of Ecotropic viral integration site 5 OS=Gallus gallus OX=9031 GN=EVI5 PE=4 SV=1 CANONICAL=A0A8V0ZMR8-1" }, "locus": { "chromosome": "8", "start_pos": 13861022, "end_pos": 13792065, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053171.1", "url": "https://www.ensembl.org/id/ENSGALT00010053171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032037.1", "url": "https://www.ensembl.org/id/ENSGALP00010032037.1" } ] } }, { "isoform_ac": "A0A8V0ZKQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8/entry#A0A8V0ZKQ7-1", "sequence": { "sequence": "MASQVASPSASLHTTSSSTTLSTPALSPSSPAQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHDFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELYVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQTNQAELLQLDMEGMLQHFQKVIPHQFDSGPDKLIQASYQVKYNAKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQSDEANTKLEQAESTIRELQQQQQWHKCSSRYSEDFVLQLEKELVQARLSEAESHCALKEMQDKVLEMEKRNSSLPDEENVARLQEELIAVKLREAEALMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPRKNTVNELQDELMTVRLREAETQAELKETKQRMMEMETQSQINNNHLRRAELEVTSLQEKVQYLTAQNKGLLAQLNEAKRRQAEIECKSKEEVMAARLREADSIAAVAELQQHIAELEIQKEEGKIQGQLNKSDSNQYIRELKDQIAELHHEIKCLKGQKDFSDQPTFDGIHIVNHFTGDDESFHSSDEDFITNSIQESGVNFHLHRRTGQMVLDRTVVDSSDSENEESTLQTGNLDKMVSKQRRMESYSTTV", "length": 823, "header": "tr|A0A8V0ZKQ7-1|A0A8V0ZKQ7_CHICK Computationally mapped isoform of Ecotropic viral integration site 5 OS=Gallus gallus OX=9031 GN=EVI5 PE=4 SV=1 CANONICAL=A0A8V0ZMR8-1" }, "locus": { "chromosome": "8", "start_pos": 13861022, "end_pos": 13799821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053098.1", "url": "https://www.ensembl.org/id/ENSGALT00010053098.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031983.1", "url": "https://www.ensembl.org/id/ENSGALP00010031983.1" } ] } }, { "isoform_ac": "A0A8V0ZME9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8/entry#A0A8V0ZME9-1", "sequence": { "sequence": "MASQVASPSASLHTTSSSTTLSTPALSPSSPAQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHDFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELYVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQTNQAELLQLDMEGMLQHFQKVIPHQFDSGPDKLIQASYQVKYNAKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQHKCSSRYSEDFVLQLEKELVQARLSEAESHCALKEMQDKVLEMEKRNSSLPDEENVARLQEELIAVKLREAEALMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPRKNTVNELQDELMTVRLREAETQAELKETKQRMMEMETQSQINNNHLRRAELEVTSLQEKVQYLTAQNKGLLAQLNEAKRRQAEIECKSKEEVMAARLREADSIAAVAELQQHIAELEIQKEEGKIQGQLNKSDSNQYIRELKDQIAELHHEIKCLKGQKDFSDQPTFDGIHIVNHFTGDDESFHSSDEDFITNSIQESGVNFHLHRRTGQMVLDRTVVDSSDSENEESTLQTGNLDKMVSKQRRMESYSTTV", "length": 774, "header": "tr|A0A8V0ZME9-1|A0A8V0ZME9_CHICK Computationally mapped isoform of Ecotropic viral integration site 5 OS=Gallus gallus OX=9031 GN=EVI5 PE=4 SV=1 CANONICAL=A0A8V0ZMR8-1" }, "locus": { "chromosome": "8", "start_pos": 13861022, "end_pos": 13799821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053100.1", "url": "https://www.ensembl.org/id/ENSGALT00010053100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031985.1", "url": "https://www.ensembl.org/id/ENSGALP00010031985.1" } ] } }, { "isoform_ac": "A0A8V0ZMR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8/entry#A0A8V0ZMR8-1", "sequence": { "sequence": "MLAGTVAAVQKGSELAEVATDKVAGKLSSTLSWVKNTVSHTVSQMASQVASPSASLHTTSSSTTLSTPALSPSSPAQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHDFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELYVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQTNQAELLQLDMEGMLQHFQKVIPHQFDSGPDKLIQASYQVKYNAKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQSDEANTKLEQAESTIRELQQQQQWHKCSSRYSEDFVLQLEKELVQARLSEAESHCALKEMQDKVLEMEKRNSSLPDEENVARLQEELIAVKLREAEALMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPRKNTVNELQDELMTVRLREAETQAELKETKQRMMEMETQSQINNNHLRRAELEVTSLQEKVQYLTAQNKGLLAQLNEAKRRQAEIECKSKEEVMAARLREADSIAAVAELQQHIAELEIQKEEGKIQGQLNKSDSNQYIRELKDQIAELHHEIKCLKGQKDFSDQPTFDGIHIVNHFTGDDESFHSSDEDFITNSIQESGVNFHLHRRTGQMVLDRTVVDSSDSENEESTLQTGNLDKMVSKQRRMESYSTTV", "length": 867, "header": "tr|A0A8V0ZMR8-1|A0A8V0ZMR8_CHICK Isoform 1 of Ecotropic viral integration site 5 OS=Gallus gallus OX=9031 GN=EVI5 PE=4 SV=1 CANONICAL=A0A8V0ZMR8-1" }, "locus": { "chromosome": "8", "start_pos": 13861022, "end_pos": 13792065, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053106.1", "url": "https://www.ensembl.org/id/ENSGALT00010053106.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031989.1", "url": "https://www.ensembl.org/id/ENSGALP00010031989.1" } ] } }, { "isoform_ac": "A0A8V0ZT41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8/entry#A0A8V0ZT41-1", "sequence": { "sequence": "MASQVASPSASLHTTSSSTTLSTPALSPSSPAQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHDFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELYVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQTNQAELLQLDMEGMLQHFQKVIPHQFDSGPDKLIQASYQVKYNAKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATIKQQSDEANTKLEQAESTIRELQQQQQWRNSSLPDEENVARLQEELIAVKLREAEALMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPRKNTVNELQDELMTVRLREAETQAELKETKQRMMEMETQSQINNNHLRRAELEVTSLQEKVQYLTAQNKGLLAQLNEAKRRQAEIECKSKEEVMAARLREADSIAAVAELQQHIAELEIQKEEGKIQGQLNKSDSNQYIRELKDQIAELHHEIKCLKGQKDFSDQPTFDGIHIVNHFTGDDESFHSSDEDFITNSIQESGVNFHLHRRTGQMVLDRTVVDSSDSENEESTLQTGNLDKMVSKQRRMESYSTTV", "length": 778, "header": "tr|A0A8V0ZT41-1|A0A8V0ZMR8_CHICK Computationally mapped isoform of Ecotropic viral integration site 5 OS=Gallus gallus OX=9031 GN=EVI5 PE=4 SV=1 CANONICAL=A0A8V0ZMR8-1" }, "locus": { "chromosome": "8", "start_pos": 13861022, "end_pos": 13799821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053091.1", "url": "https://www.ensembl.org/id/ENSGALT00010053091.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031977.1", "url": "https://www.ensembl.org/id/ENSGALP00010031977.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 745, "end_pos": 747, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR8" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 163, "end_pos": 348, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 126, "end_pos": 128 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 745, "end_pos": 747 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMR2-1", "uniprot_ac": "A0A8V0ZMR2", "uniprot_id": "A0A8V0ZMR2_CHICK", "mass": { "chemical_mass": 118147.0, "monoisotopic_mass": 118147.0 }, "refseq": { "ac": "XP_040504143", "name": "ATPase MORC2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504143" }, "gene_names": [ { "name": "MORC1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR2" } ] }, { "name": "MORC1", "type": "synonym", "evidence": [ { "id": "XP_040504143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504143" } ] } ], "protein_names": [ { "name": "ATPase MORC2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040504143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504143" } ] }, { "name": "MORC family CW-type zinc finger 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040504143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504143" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MORC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR2", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZMR2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMR2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007512", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007512", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16931", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16931", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858829", "url": "https://www.ncbi.nlm.nih.gov/gene/100858829", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NFASKTF", "url": "https://omabrowser.org/oma/group/NFASKTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q3B150", "url": "https://www.orthodb.org/?gene=A0A3Q3B150", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL07", "url": "https://www.orthodb.org/?gene=A0A8V0ZL07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMQ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZMQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMR2", "url": "https://www.orthodb.org/?gene=A0A8V0ZMR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTG0", "url": "https://www.orthodb.org/?gene=A0A8V0ZTG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23337:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23337:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17942", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17942", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23327", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23327", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-75105", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75105", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9843970", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9843970", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040504143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040504143", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q3B150", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B150", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3B150-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B150-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCANYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNASYRERNSCSVEKILRDADATRIDIYTERREDLRGGFMLCFLDDGTGMDSNEAASVIQFGKSAKRSPESTQIGQYGNGLKSGSMRIGKDFILFTKKSNTMTCLLLSRTFHEEEGIDEVIVPLPTWNVWNREPVSDNMEKFAIETELIYKYSPFKSEQEVMEQFNKIRGEKGTLVIIFNLKLMDNGEPELDVTSDPRDIQMAETPPEGTKPERRSFRAYAAVLYIDPRMRIFINGHKVQTKRLSCCLYKPRMYKYTSNRFKTRAEQEVKKAEHMARIAEEKAREAESKARAFELRLGGDLTRESRVTLRQVQNSAITMRREADVKKRIKDAKQRALKEPKELNFIFGVNIEQRELDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLKAMGEHLAQYWKDVAIAQRGIVKFWDEFGYLSAKWSQPPSSELRYKRRRAMEIPTTIQCDVCLKWRTLPFQLSSVEKNYPDSWVCSMNPDPEQNRCEAPEQKQKLPLGTLKKDSKSQEEKQKQLSEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVSTRPAGEPVTRSQRPRSPPLPDVIKNAPSRPPPLTPPSKSVSQLKKSSSTWTNINTPRLASILSKEEASTSKTHHDAVTAGKSNSTSKTLAKPTTPTKPSSAVPLSPKSPRETPNSKTAKVSTPKKSATVKSPQACTPRKRTMHTAEELSEEEVESKKERTKRGKFVAVKEENKDPSEVVVELTDSAGEEDVAELKKAQKDKGLRVEVRVNKEWFTGRVTAVEIGKHAVRWKVKFDYVPTATTPRDRWVEKDSEDVRLMKPPSPEYQSPDTQQEEEVVVAEPSTSECVGIEPDTTGPSSGQETVDLLVQILRNCLRYFLPPNFPISKKELSSMSSEGLLAFPLKDYFKQYEMGLQNLCNSYQTRADARAKACEENLHNTERKLKETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD", "length": 1039, "header": "tr|A0A8V0ZMR2-1|A0A8V0ZMR2_CHICK Isoform 1 of MORC family CW-type zinc finger 1 OS=Gallus gallus OX=9031 GN=MORC1 PE=4 SV=1 CANONICAL=A0A8V0ZMR2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3B150-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR2/entry#A0A3Q3B150-1", "sequence": { "sequence": "MSCANYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYTERREDLRGGFMLCFLDDGTGMDSNEAASVIQFGKSAKRSPESTQIGQYGNGLKSGSMRIGKDFILFTKKSNTMTCLLLSRTFHEEEGIDEVIVPLPTWNVWNREPVSDNMEKFAIETELIYKYSPFKSEQEVMEQFNKIRGEKGTLVIIFNLKLMDNGEPELDVTSDPRDIQMAETPPEGTKPERRSFRAYAAVLYIDPRMRIFINGHKVQTKRLSCCLYKPRMYKYTSNRFKTRAEQEVKKAEHMARIAEEKAREAESKARAFELRLGGDLTRESRVTLRQVQNSAITMRREADVKKRIKDAKQRALKEPKELNFIFGVNIEQRELDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLKAMGEHLAQYWKDVAIAQRGIVKFWDEFGYLSAKWSQPPSSELRYKRRRAMEIPTTIQCDVCLKWRTLPFQLSSVEKNYPDSWVCSMNPDPEQNRCEAPEQKQKLPLGTLKKDSKSQEEKQKQLSEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVSTRPAGEPVTRSQRPRSPPLPDVIKNAPSRPPPLTPPSKSVSQLKKSSSTWTNINTPRLASILSKEEASTSKTHHDAVTAGKSNSTSKTLAKPTTPTKPSSAVPLSPKSPRETPNSKTAKVSTPKKSATVKSPQACTPRKRTMHTAEELSEEEVESKKERTKRGKFVAVKEENKDPSEVVVELTDSAGEEDVAELKKAQKDKGLRVEVRVNKEWFTGRVTAVEIGKHAVRWKVKFDYVPTATTPRDRWVEKDSEDVRLMKPPSPEYQSPDTQQEEEVVVAEPSTSECVGIEPDTTGPSSGQETVDLLVQILRNCLRYFLPPNFPISKKELSSMSSEGLLAFPLMTRLTEMEQN", "length": 950, "header": "tr|A0A3Q3B150-1|A0A8V0ZMR2_CHICK Computationally mapped isoform of MORC family CW-type zinc finger 1 OS=Gallus gallus OX=9031 GN=MORC1 PE=4 SV=1 CANONICAL=A0A8V0ZMR2-1" }, "locus": { "chromosome": "15", "start_pos": 9965032, "end_pos": 9930073, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053261.1", "url": "https://www.ensembl.org/id/ENSGALT00010053261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032100.1", "url": "https://www.ensembl.org/id/ENSGALP00010032100.1" } ] } }, { "isoform_ac": "A0A8V0ZL07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR2/entry#A0A8V0ZL07-1", "sequence": { "sequence": "MSCANYSSLNRAQLTFEYLHTNSDADATRIDIYTERREDLRGGFMLCFLDDGTGMDSNEAASVIQFGKSAKRSPESTQIGQYGNGLKSGSMRIGKDFILFTKKSNTMTCLLLSRTFHEEEGIDEVIVPLPTWNVWNREPVSDNMEKFAIETELIYKYSPFKSEQEVMEQFNKIRGEKGTLVIIFNLKLMDNGEPELDVTSDPRDIQMAETPPEGTKPERRSFRAYAAVLYIDPRMRIFINGHKVQTKRLSCCLYKPRMYKYTSNRFKTRAEQEVKKAEHMARIAEEKAREAESKARAFELRLGGDLTRESRVTLRQVQNSAITMRREADVKKRIKDAKQRALKEPKELNFIFGVNIEQRELDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLKAMGEHLAQYWKDVAIAQRGIVKFWDEFGYLSAKWSQPPSSELRYKRRRAMEIPTTIQCDVCLKWRTLPFQLSSVEKNYPDSWVCSMNPDPEQNRCEAPEQKQKLPLGTLKKDSKSQEEKQKQLSEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVSTRPAGEPVTRSQRPRSPPLPDVIKNAPSRPPPLTPPSKSVSQLKKSSSTWTNINTPRLASILSKEEASTSKTHHDAVTAGKSNSTSKTLAKPTTPTKPSSAVPLSPKSPRETPNSKTAKVSTPKKSATVKSPQACTPRKRTMHTAEELSEEEVESKKERTKRGKFVAVKEENKDPSEVVVELTDSAGEEDVAELKKAQKDKGLRVEVRVNKEWFTGRVTAVEIGKHAVRWKVKFDYVPTATTPRDRWVEKDSEDVRLMKPPSPEYQSPDTQQEEEVVVAEPSTSECVGIEPDTTGPSSGQETVDLLVQILRNCLRYFLPPNFPISKKELSSMSSEGLLAFPLKDYFKQYEMGLQNLCNSYQTRADARAKACEENLHNTERKLKETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD", "length": 1007, "header": "tr|A0A8V0ZL07-1|A0A8V0ZL07_CHICK Computationally mapped isoform of MORC family CW-type zinc finger 1 OS=Gallus gallus OX=9031 GN=MORC1 PE=4 SV=1 CANONICAL=A0A8V0ZMR2-1" }, "locus": { "chromosome": "15", "start_pos": 9965032, "end_pos": 9928501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053270.1", "url": "https://www.ensembl.org/id/ENSGALT00010053270.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032105.1", "url": "https://www.ensembl.org/id/ENSGALP00010032105.1" } ] } }, { "isoform_ac": "A0A8V0ZMQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR2/entry#A0A8V0ZMQ7-1", "sequence": { "sequence": "MLCFLDDGTGMDSNEAASVIQFGKSAKRSPESTQIGQYGNGLKSGSMRIGKDFILFTKKSNTMTCLLLSRTFHEEEGIDEVIVPLPTWNVWNREPVSDNMEKFAIETELIYKYSPFKSEQEVMEQFNKIRGEKGTLVIIFNLKLMDNGEPELDVTSDPRDIQMAETPPEGTKPERRSFRAYAAVLYIDPRMRIFINGHKVQTKRLSCCLYKPRMYKYTSNRFKTRAEQEVKKAEHMARIAEEKAREAESKARAFELRLGGDLTRESRVTLRQVQNSAITMRREADVKKRIKDAKQRALKEPKELNFIFGVNIEQRELDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLKAMGEHLAQYWKDVAIAQRGIVKFWDEFGYLSAKWSQPPSSELRYKRRRAMEIPTTIQCDVCLKWRTLPFQLSSVEKNYPDSWVCSMNPDPEQNRCEAPEQKQKLPLGTLKKDSKSQEEKQKQLSEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVSTRPAGEPVTRSQRPRSPPLPDVIKNAPSRPPPLTPPSKSVSQLKKSSSTWTNINTPRLASILSKEEASTSKTHHDAVTAGKSNSTSKTLAKPTTPTKPSSAVPLSPKSPRETPNSKTAKVSTPKKSATVKSPQACTPRKRTMHTAEELSEEEVESKKERTKRGKFVAVKEENKDPSEVVVELTDSAGEEDVAELKKAQKDKGLRVEVRVNKEWFTGRVTAVEIGKHAVRWKVKFDYVPTATTPRDRWVEKDSEDVRLMKPPSPEYQSPDTQQEEEVVVAEPSTSECVGIEPDTTGPSSGQETVDLLVQILRNCLRYFLPPNFPISKKELSSMSSEGLLAFPLKDYFKQYEMGLQNLCNSYQTRADARAKACEENLHNTERKLKETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD", "length": 963, "header": "tr|A0A8V0ZMQ7-1|A0A8V0ZMQ7_CHICK Computationally mapped isoform of MORC family CW-type zinc finger 1 OS=Gallus gallus OX=9031 GN=MORC1 PE=4 SV=1 CANONICAL=A0A8V0ZMR2-1" }, "locus": { "chromosome": "15", "start_pos": 9957341, "end_pos": 9928501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053265.1", "url": "https://www.ensembl.org/id/ENSGALT00010053265.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032102.1", "url": "https://www.ensembl.org/id/ENSGALP00010032102.1" } ] } }, { "isoform_ac": "A0A8V0ZMR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR2/entry#A0A8V0ZMR2-1", "sequence": { "sequence": "MSCANYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNASYRERNSCSVEKILRDADATRIDIYTERREDLRGGFMLCFLDDGTGMDSNEAASVIQFGKSAKRSPESTQIGQYGNGLKSGSMRIGKDFILFTKKSNTMTCLLLSRTFHEEEGIDEVIVPLPTWNVWNREPVSDNMEKFAIETELIYKYSPFKSEQEVMEQFNKIRGEKGTLVIIFNLKLMDNGEPELDVTSDPRDIQMAETPPEGTKPERRSFRAYAAVLYIDPRMRIFINGHKVQTKRLSCCLYKPRMYKYTSNRFKTRAEQEVKKAEHMARIAEEKAREAESKARAFELRLGGDLTRESRVTLRQVQNSAITMRREADVKKRIKDAKQRALKEPKELNFIFGVNIEQRELDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLKAMGEHLAQYWKDVAIAQRGIVKFWDEFGYLSAKWSQPPSSELRYKRRRAMEIPTTIQCDVCLKWRTLPFQLSSVEKNYPDSWVCSMNPDPEQNRCEAPEQKQKLPLGTLKKDSKSQEEKQKQLSEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVSTRPAGEPVTRSQRPRSPPLPDVIKNAPSRPPPLTPPSKSVSQLKKSSSTWTNINTPRLASILSKEEASTSKTHHDAVTAGKSNSTSKTLAKPTTPTKPSSAVPLSPKSPRETPNSKTAKVSTPKKSATVKSPQACTPRKRTMHTAEELSEEEVESKKERTKRGKFVAVKEENKDPSEVVVELTDSAGEEDVAELKKAQKDKGLRVEVRVNKEWFTGRVTAVEIGKHAVRWKVKFDYVPTATTPRDRWVEKDSEDVRLMKPPSPEYQSPDTQQEEEVVVAEPSTSECVGIEPDTTGPSSGQETVDLLVQILRNCLRYFLPPNFPISKKELSSMSSEGLLAFPLKDYFKQYEMGLQNLCNSYQTRADARAKACEENLHNTERKLKETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD", "length": 1039, "header": "tr|A0A8V0ZMR2-1|A0A8V0ZMR2_CHICK Isoform 1 of MORC family CW-type zinc finger 1 OS=Gallus gallus OX=9031 GN=MORC1 PE=4 SV=1 CANONICAL=A0A8V0ZMR2-1" }, "locus": { "chromosome": "15", "start_pos": 9965032, "end_pos": 9928501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053273.1", "url": "https://www.ensembl.org/id/ENSGALT00010053273.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032107.1", "url": "https://www.ensembl.org/id/ENSGALP00010032107.1" } ] } }, { "isoform_ac": "A0A8V0ZTG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMR2/entry#A0A8V0ZTG0-1", "sequence": { "sequence": "MSCANYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYTDEAASVIQFGKSAKRSPESTQIGQYGNGLKSGSMRIGKDFILFTKKSNTMTCLLLSRTFHEEEGIDEVIVPLPTWNVWNREPVSDNMEKFAIETELIYKYSPFKSEQEVMEQFNKIRGEKGTLVIIFNLKLMDNGEPELDVTSDPRDIQMAETPPEGTKPERRSFRAYAAVLYIDPRMRIFINGHKVQTKRLSCCLYKPRMYKYTSNRFKTRAEQEVKKAEHMARIAEEKAREAESKARAFELRLGGDLTRESRVTLRQVQNSAITMRREADVKKRIKDAKQRALKEPKELNFIFGVNIEQRELDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLKAMGEHLAQYWKDVAIAQRGIVKFWDEFGYLSAKWSQPPSSELRYKRRRAMEIPTTIQCDVCLKWRTLPFQLSSVEKNYPDSWVCSMNPDPEQNRCEAPEQKQKLPLGTLKKDSKSQEEKQKQLSEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVSTRPAGEPVTRSQRPRSPPLPDVIKNAPSRPPPLTPPSKSVSQLKKSSSTWTNINTPRLASILSKEEASTSKTHHDAVTAGKSNSTSKTLAKPTTPTKPSSAVPLSPKSPRETPNSKTAKVSTPKKSATVKSPQACTPRKRTMHTAEELSEEEVESKKERTKRGKFVAVKEENKDPSEVVVELTDSAGEEDVAELKKAQKDKGLRVEVRVNKEWFTGRVTAVEIGKHAVRWKVKFDYVPTATTPRDRWVEKDSEDVRLMKPPSPEYQSPDTQQEEEVVVAEPSTSECVGIEPDTTGPSSGQETVDLLVQILRNCLRYFLPPNFPISKKELSSMSSEGLLAFPLKDYFKQYEMGLQNLCNSYQTRADARAKACEENLHNTERKLKETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD", "length": 1002, "header": "tr|A0A8V0ZTG0-1|A0A8V0ZMR2_CHICK Computationally mapped isoform of MORC family CW-type zinc finger 1 OS=Gallus gallus OX=9031 GN=MORC1 PE=4 SV=1 CANONICAL=A0A8V0ZMR2-1" }, "locus": { "chromosome": "15", "start_pos": 9965032, "end_pos": 9928501, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053277.1", "url": "https://www.ensembl.org/id/ENSGALT00010053277.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032109.1", "url": "https://www.ensembl.org/id/ENSGALP00010032109.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-75105", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75105", "resource": "Reactome", "description": "Fatty acyl-CoA biosynthesis" }, { "id": "R-GGA-9843970", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9843970", "resource": "Reactome", "description": "Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JWF7-1", "protein_name": "MORC family CW-type zinc finger 2", "gene_name": "Morc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFTNYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYAERREDLRGGFMLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPITDNVEKFAIETELVYKYSPFHTEEQVMNQFMKIPGNSGTLVIIFNLKLMDNGEPELDIISNPKDIQMAETSPEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRMGGDLTRDSRVMLRQVQNAAITLRREADVKKRIKDAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSELRFKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTLKKDPKSQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIKNAPSRPPSIQTPRPATQLRKTSVISSPKPPATAARGETSTSRILQPAEAPRKPANLPIKTVPRPTPTVQTPSPSLIPNSKNLREVPAQKAIKTPMVKKPEPPAKQSMASSGRKRSLVVSDEEEAEEEAEKRKERCKRGKLAVKEEKKEANELSDSAGEDDPAELKKAQKDKGLHVEVRVNREWYTGRVTAVEMGKNVVRWKVKFDYVPTDTTPRDRWVEKGSEDVRLMKPPSPEHQSPDTQQEGGEEEEAMVAQQAVALPEPSTSDGLPIEPDTTATSTSHETIDLLVQILRNCLRYFLPPSFPISKKELSVMNSEELISFPLKEYFKQYEVGLQNLCHSYQSRADSRAKASEESLRTSEKKLRETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD", "length": 1031 }, "evidence": [ { "id": "A0A8V0ZMR2", "url": "https://omabrowser.org/oma/group/A0A8V0ZMR2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q69ZX6-1", "protein_name": "ATPase MORC2A", "gene_name": "Morc2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFTNYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYAERREDLRGGFMLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPITDNVEKFAIETELVYKYSPFHTEEQVMNQFMKIPGNSGTLVIIFNLKLMDNGEPELDIISNPKDIQMAETSPEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRMGGDLTRDSRVMLRQVQNTAITLRREADVKKRIKDAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSELRFKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVETDYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTLKKDPKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPIEEPVRRPQRPRSPPLPAVIKNAPSRPPSIQTPRPSTQLRKTSVISLPKPPTTAARGETSTSRLLQPTEAPRKPANPPIKTVPRPTPPVHTPPLSLIPSSKSLREVPAQKAIKTPVVKKPEPPVKQSVATSGRKRSLAVSDEEEAEEEAEKRRERCKRGKLAVKEEKKEANELSDSAGEDHPAELRKAQKDKGLHVEVRVNREWYTGRVTAVEVGKNAVRWKVKFDYVPTDTTPRDRWVEKGSEDVRLMKPPSPEHQSPDTQQEGGEEEEAMVARQAVALPEPSTSDGLPIEPDTTATSPSHETIDLLVQILRNCLRYFLPPSFPISKKELSVMNSEELISFPLKEYFKQYEVGLQNLCHSYQSRADSRAKASEESLRTSEKKLRETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD", "length": 1030 }, "evidence": [ { "id": "A0A8V0ZMR2", "url": "https://omabrowser.org/oma/group/A0A8V0ZMR2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6X9-1", "protein_name": "ATPase MORC2", "gene_name": "MORC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFTNYSSLNRAQLTFEYLHTNSTTHEFLFGALAELVDNARDADATRIDIYAERREDLRGGFMLCFLDDGAGMDPSDAASVIQFGKSAKRTPESTQIGQYGNGLKSGSMRIGKDFILFTKKEDTMTCLFLSRTFHEEEGIDEVIVPLPTWNARTREPVTDNVEKFAIETELIYKYSPFRTEEEVMTQFMKIPGDSGTLVIIFNLKLMDNGEPELDIISNPRDIQMAETSPEGTKPERRSFRAYAAVLYIDPRMRIFIHGHKVQTKRLSCCLYKPRMYKYTSSRFKTRAEQEVKKAEHVARIAEEKAREAESKARTLEVRLGGDLTRDSRVMLRQVQNRAITLRREADVKKRIKEAKQRALKEPKELNFVFGVNIEHRDLDGMFIYNCSRLIKMYEKVGPQLEGGMACGGVVGVVDVPYLVLEPTHNKQDFADAKEYRHLLRAMGEHLAQYWKDIAIAQRGIIKFWDEFGYLSANWNQPPSSELRYKRRRAMEIPTTIQCDLCLKWRTLPFQLSSVEKDYPDTWVCSMNPDPEQDRCEASEQKQKVPLGTFRKDMKTQEEKQKQLTEKIRQQQEKLEALQKTTPIRSQADLKKLPLEVTTRPSTEEPVRRPQRPRSPPLPAVIRNAPSRPPSLPTPRPASQPRKAPVISSTPKLPALAAREEASTSRLLQPPEAPRKPANTLVKTASRPAPLVQQLSPSLLPNSKSPREVPSPKVIKTPVVKKTESPIKLSPATPSRKRSVAVSDEEEVEEEAERRKERCKRGRFVVKEEKKDSNELSDSAGEEDSADLKRAQKDKGLHVEVRVNREWYTGRVTAVEVGKHVVRWKVKFDYVPTDTTPRDRWVEKGSEDVRLMKPPSPEHQSLDTQQEGGEEEVGPVAQQAIAVAEPSTSECLRIEPDTTALSTNHETIDLLVQILRNCLRYFLPPSFPISKKQLSAMNSDELISFPLKEYFKQYEVGLQNLCNSYQSRADSRAKASEESLRTSERKLRETEEKLQKLRTNIVALLQKVQEDIDINTDDELDAYIEDLITKGD", 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"https://www.ensembl.org/id/ENSGALG00010021718" } ] } } ], "crossref": [ { "id": "A0A8V0ZJX2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJX2", "url": "https://www.orthodb.org/?gene=A0A8V0ZJX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSC1", "url": "https://www.orthodb.org/?gene=A0A8V0ZSC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSC6", "url": "https://www.orthodb.org/?gene=A0A8V0ZSC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10558", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10558", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10558:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10558:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-375276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-375276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZJX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLVASLVSVLLLVWSVRATALPGEERLALQNSRAKEEQTKLRRDALLKMLAGLLESSDVASPDLEEEGKLEEERAALGRLAQLSQRDRKAPCKNFFWKTFTSC", "length": 104, "header": "tr|A0A8V0ZJX2-1|A0A8V0ZJX2_CHICK Isoform 1 of Somatostatin 7 OS=Gallus gallus OX=9031 GN=SST7 PE=3 SV=1 CANONICAL=A0A8V0ZJX2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX2/entry#A0A8V0ZJX2-1", "sequence": { "sequence": "MQLVASLVSVLLLVWSVRATALPGEERLALQNSRAKEEQTKLRRDALLKMLAGLLESSDVASPDLEEEGKLEEERAALGRLAQLSQRDRKAPCKNFFWKTFTSC", "length": 104, "header": "tr|A0A8V0ZJX2-1|A0A8V0ZJX2_CHICK Isoform 1 of Somatostatin 7 OS=Gallus gallus OX=9031 GN=SST7 PE=3 SV=1 CANONICAL=A0A8V0ZJX2-1" }, "locus": { "chromosome": "21", "start_pos": 4099865, "end_pos": 4096299, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052780.1", "url": "https://www.ensembl.org/id/ENSGALT00010052780.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031686.1", "url": "https://www.ensembl.org/id/ENSGALP00010031686.1" } ] } }, { "isoform_ac": "A0A8V0ZSC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX2/entry#A0A8V0ZSC1-1", "sequence": { "sequence": "TALRGNLLEQADPACQQQGQGDVCADLCVCFIPLQLQERNNRTSPHVECVNPRVRLSQPSDPWQAQPCVLTSVPSCFCLNSHKAQSICNPSGIPCHGWDEPGVAELVASLVSVLLLVWSVRATALPGEERLALQNSREQTKLRRDALLKMLAGLLESSDVASPDLEEEGKLEEERAALGRLAQLSQRDRKAPCKNFFWKTFTSC", "length": 204, "header": "tr|A0A8V0ZSC1-1|A0A8V0ZJX2_CHICK Computationally mapped isoform of Somatostatin 7 OS=Gallus gallus OX=9031 GN=SST7 PE=3 SV=1 CANONICAL=A0A8V0ZJX2-1" }, "locus": { "chromosome": "21", "start_pos": 4104337, "end_pos": 4096299, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052784.1", "url": "https://www.ensembl.org/id/ENSGALT00010052784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031690.1", "url": "https://www.ensembl.org/id/ENSGALP00010031690.1" } ] } }, { "isoform_ac": "A0A8V0ZSC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX2/entry#A0A8V0ZSC6-1", "sequence": { "sequence": "QVQAFYPPSLQERNNRTSPHVECVNPRVRLSQPSDPWQAQPCVLTSVPSCFCLNSHKAQSICNPSGIPCHGWDEPGVAELVASLVSVLLLVWSVRATALPGEERLALQNSREQTKLRRDALLKMLAGLLESSDVASPDLEEEGKLEEERAALGRLAQLSQRDRKAPCKNFFWKTFTSC", "length": 178, "header": "tr|A0A8V0ZSC6-1|A0A8V0ZJX2_CHICK Computationally mapped isoform of Somatostatin 7 OS=Gallus gallus OX=9031 GN=SST7 PE=3 SV=1 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"https://www.uniprot.org/uniprotkb/A0A8V0ZJX2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX2" } ], "pmid": "" }, { "name": "neuropeptide hormone activity", "id": "GO:0005184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005184", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX2" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], 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"uniprot_ac": "A0A8V0ZKU4", "uniprot_id": "A0A8V0ZKU4_CHICK", "mass": { "chemical_mass": 25678.0, "monoisotopic_mass": 25678.0 }, "refseq": { "ac": "XP_414889", "name": "BTB/POZ domain-containing protein KCTD5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414889" }, "gene_names": [ { "name": "KCTD5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4" } ] }, { "name": "KCTD5", "type": "synonym", "evidence": [ { "id": "XP_414889", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414889" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein KCTD5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_414889", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414889" } ] }, { "name": "Potassium channel tetramerization domain containing 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414889" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCTD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZKU4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKU4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18390", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18390", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416589", "url": "https://www.ncbi.nlm.nih.gov/gene/416589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LPGKWVR", "url": "https://omabrowser.org/oma/group/LPGKWVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKT0", "url": "https://www.orthodb.org/?gene=A0A8V0ZKT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKT9", "url": "https://www.orthodb.org/?gene=A0A8V0ZKT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKU4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT21", "url": "https://www.orthodb.org/?gene=A0A8V0ZT21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14958", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14958", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14958:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14958:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414889", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAENHCDFPVAPIGGLGLGGPGGPCRRCSSAPPPGAVPGKWVRLNVGGTCFLTTRQTLCRDPKSFLFRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKISQVPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTTSEPSEKAKILQERGSRM", "length": 231, "header": "tr|A0A8V0ZKU4-1|A0A8V0ZKU4_CHICK Isoform 1 of Potassium channel tetramerization domain containing 5 OS=Gallus gallus OX=9031 GN=KCTD5 PE=4 SV=1 CANONICAL=A0A8V0ZKU4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4/entry#A0A8V0ZKT0-1", "sequence": { "sequence": "AEHQLEVAVCLCLHEGGRSCIFSIPFFCLFFRRCTYNTYLVHGSSQYPDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKISQVPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSQYGCGRAQQSEYLLIVSREVKGEERCFQKCCSELVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTTSEPSEKAKILQERGSRM", "length": 237, "header": "tr|A0A8V0ZKT0-1|A0A8V0ZKT0_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 5 OS=Gallus gallus OX=9031 GN=KCTD5 PE=4 SV=1 CANONICAL=A0A8V0ZKU4-1" }, "locus": { "chromosome": "14", "start_pos": 7406565, "end_pos": 7388596, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056157.1", "url": "https://www.ensembl.org/id/ENSGALT00010056157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033979.1", "url": "https://www.ensembl.org/id/ENSGALP00010033979.1" } ] } }, { "isoform_ac": "A0A8V0ZKT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4/entry#A0A8V0ZKT9-1", "sequence": { "sequence": "MAAENHCDFPVAPIGGLGLGGPGGPCRRCSSAPPPGAVPGKWVRLNVGGTCFLTTRQTLCRDPKSFLFRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKISQVPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTTSEPSEKAKEKRRKFKLQNGVSHPLSN", "length": 240, "header": "tr|A0A8V0ZKT9-1|A0A8V0ZKT9_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 5 OS=Gallus gallus OX=9031 GN=KCTD5 PE=4 SV=1 CANONICAL=A0A8V0ZKU4-1" }, "locus": { "chromosome": "14", "start_pos": 7403750, "end_pos": 7382679, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056171.1", "url": "https://www.ensembl.org/id/ENSGALT00010056171.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033989.1", "url": "https://www.ensembl.org/id/ENSGALP00010033989.1" } ] } }, { "isoform_ac": "A0A8V0ZKU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4/entry#A0A8V0ZKU4-1", "sequence": { "sequence": "MAAENHCDFPVAPIGGLGLGGPGGPCRRCSSAPPPGAVPGKWVRLNVGGTCFLTTRQTLCRDPKSFLFRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKISQVPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTTSEPSEKAKILQERGSRM", "length": 231, "header": "tr|A0A8V0ZKU4-1|A0A8V0ZKU4_CHICK Isoform 1 of Potassium channel tetramerization domain containing 5 OS=Gallus gallus OX=9031 GN=KCTD5 PE=4 SV=1 CANONICAL=A0A8V0ZKU4-1" }, "locus": { "chromosome": "14", "start_pos": 7406565, "end_pos": 7382679, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056176.1", "url": "https://www.ensembl.org/id/ENSGALT00010056176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033994.1", "url": "https://www.ensembl.org/id/ENSGALP00010033994.1" } ] } }, { "isoform_ac": "A0A8V0ZT21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4/entry#A0A8V0ZT21-1", "sequence": { "sequence": "MAAENHCDFPVAPIGGLGLGGPGGPCRRCSSAPPPGAVPGKWVRLNVGGTCFLTTRQTLCRDPKSFLFRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKISQVPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSQYGCGRAQQSEYLLIVSREVKGEERCFQKCCSELVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTTSEPSEKAKILQERGSRM", "length": 270, "header": "tr|A0A8V0ZT21-1|A0A8V0ZKU4_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 5 OS=Gallus gallus OX=9031 GN=KCTD5 PE=4 SV=1 CANONICAL=A0A8V0ZKU4-1" }, "locus": { "chromosome": "14", "start_pos": 7406565, "end_pos": 7382679, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056164.1", "url": "https://www.ensembl.org/id/ENSGALT00010056164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033983.1", "url": "https://www.ensembl.org/id/ENSGALP00010033983.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A5PKG7-1", "protein_name": "BTB/POZ domain-containing protein KCTD5", "gene_name": "KCTD5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAENHCELLPPAPGGLGAGLGGGLCRRCSAGLGALAQRPGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQVPLKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGSEDQAEFLCVVSKELHNSPHGPASEPSEKAKILQERGSRM", "length": 234 }, "evidence": [ { "id": "A0A8V0ZKU4", "url": "https://omabrowser.org/oma/group/A0A8V0ZKU4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SUH5-1", "protein_name": "Potassium channel tetramerization domain containing 5", "gene_name": "KCTD5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAESHCELLPPAPGGLGAGLGGSLCRRCSAGLGTLAQRPGNVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQVPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVNIGSSYNYGSEDQSEFLCVVSKELHNSPYGTASEPSEKAKILQERGSRM", "length": 234 }, "evidence": [ { "id": "A0A8V0ZKU4", "url": "https://omabrowser.org/oma/group/A0A8V0ZKU4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8VC57-1", "protein_name": "BTB/POZ domain-containing protein KCTD5", "gene_name": "Kctd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAENHCELLPPAPSGLGAGLGGGLCRRCSAGMGALAQRPGGVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSRISQMPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTTSEPSEKAKILQERGSRM", "length": 234 }, "evidence": [ { "id": "A0A8V0ZKU4", "url": "https://omabrowser.org/oma/group/A0A8V0ZKU4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NXV2-1", "protein_name": "BTB/POZ domain-containing protein KCTD5", "gene_name": "KCTD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAENHCELLSPARGGIGAGLGGGLCRRCSAGLGALAQRPGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQVPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTASEPSEKAKILQERGSRM", "length": 234 }, "evidence": [ { "id": "A0A8V0ZKU4", "url": "https://omabrowser.org/oma/group/A0A8V0ZKU4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W579-1", "protein_name": "Insomniac, isoform B", "gene_name": "inc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTVFINSRKSPNVLKKQGTDQWVKLNVGGTYFLTTKTTLSRDPNSFLSRLIQEDCDLISDRDETGAYLIDRDPKYFAPVLNYLRHGKLVLDGVSEEGVLEEAEFYNVTQLIALLKECILHRDQRPQTDKKRVYRVLQCREQELTQMISTLSDGWRFEQLISMQYTNYGPFENNEFLCVVSKECGTTAGRELELNDRAKVLQQKGSRILGI", "length": 211 }, "evidence": [ { "id": "A0A8V0ZKU4", "url": "https://omabrowser.org/oma/group/A0A8V0ZKU4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": 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{ "database": "UniProtKB", "id": "A0A8V0ZKU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU4" }, { "id": "SM00225", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 143, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMW6-1", "uniprot_ac": "A0A8V0ZMW6", "uniprot_id": "A0A8V0ZMW6_CHICK", "mass": { "chemical_mass": 39138.0, "monoisotopic_mass": 39138.0 }, "refseq": {}, "gene_names": [ { "name": "TMOD3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW6" } ] } ], "protein_names": [ { "name": "Tropomodulin 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMOD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW6", "locus": { "chromosome": "10", "start_pos": 9032731, "end_pos": 9058488, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023432", "url": "https://www.ensembl.org/id/ENSGALG00010023432" } ] } } ], "crossref": [ { "id": "A0A8V0ZMW6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMW6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMW1", "url": "https://www.orthodb.org/?gene=A0A8V0ZMW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMW6", "url": "https://www.orthodb.org/?gene=A0A8V0ZMW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT40", "url": "https://www.orthodb.org/?gene=A0A8V0ZT40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10901", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10901", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10901:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10901:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-390522", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390522", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013418", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013418", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZMW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLPFRKDLDKYKDLDEDDILGKLSEEELKQLETVLDDLDPENALLPAGFRQKDQTAKKASGPFDRERLLAYLEKQALEHKDREDYVPFTKEKKGKVFIPKQKPAQSYAEEKIALDPELEEALTSATDTELCDLAAILGMSNLITNNQFCDIVGSSNGVGKDSFSNIVKGEKMLPVFDEPPNPTNVEETLQRIKDNDSRLVEVNLNNIKPIPTLKEFAKALETNTHVKNFSLAATRSNDPVAVALADMLRVNTKLKSLNIESNFITGVGILALVDALKDNETLTEIKIDNQRQQLGTLAEVEIAKMLEENTKILKFGYHFTQQGPRARAAAAITKNNDLVRKRRVEGDGQ", "length": 350, "header": "tr|A0A8V0ZMW6-1|A0A8V0ZMW6_CHICK Isoform 1 of Tropomodulin 3 OS=Gallus gallus OX=9031 GN=TMOD3 PE=1 SV=1 CANONICAL=A0A8V0ZMW6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW6/entry#A0A8V0ZMW1-1", "sequence": { "sequence": "MTLPFRKDLDKYKDLDEDDILGKLSEEELKQLETVLDDLDPENALLPAGFRQKDQTAKKASGPFDRERLLAYLEKQALEHKDREDYVPFTKEKKGKVFIPKQKPAQSYAEEKIALDPELEEALTSATDTELCDLAAILGMSNLITNNQFCDIVGSSNGVGKDSFSNIVKGEKMLPVFDEPPNPTNVEETLQRIKDNDSRLVEVNLNNIKNIPIPTLKEFAKALETNTHVKNFSLAATRSNDPVAVALADMLRVNTKLKSLNIESNFITGVGILALVDALKDNETLTEIKIDNQRQQLGTLAEVEIAKMLEENTKILKFGYHFTQQGPRARAAAAITKNNDLVWSSRVKISANTFSPLQP", "length": 359, "header": "tr|A0A8V0ZMW1-1|A0A8V0ZMW1_CHICK Computationally mapped isoform of Tropomodulin 3 OS=Gallus gallus OX=9031 GN=TMOD3 PE=1 SV=1 CANONICAL=A0A8V0ZMW6-1" }, "locus": { "chromosome": "10", "start_pos": 9052606, "end_pos": 9036482, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057105.1", "url": "https://www.ensembl.org/id/ENSGALT00010057105.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034736.1", "url": "https://www.ensembl.org/id/ENSGALP00010034736.1" } ] } }, { "isoform_ac": "A0A8V0ZMW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW6/entry#A0A8V0ZMW6-1", "sequence": { "sequence": "MTLPFRKDLDKYKDLDEDDILGKLSEEELKQLETVLDDLDPENALLPAGFRQKDQTAKKASGPFDRERLLAYLEKQALEHKDREDYVPFTKEKKGKVFIPKQKPAQSYAEEKIALDPELEEALTSATDTELCDLAAILGMSNLITNNQFCDIVGSSNGVGKDSFSNIVKGEKMLPVFDEPPNPTNVEETLQRIKDNDSRLVEVNLNNIKPIPTLKEFAKALETNTHVKNFSLAATRSNDPVAVALADMLRVNTKLKSLNIESNFITGVGILALVDALKDNETLTEIKIDNQRQQLGTLAEVEIAKMLEENTKILKFGYHFTQQGPRARAAAAITKNNDLVRKRRVEGDGQ", "length": 350, "header": "tr|A0A8V0ZMW6-1|A0A8V0ZMW6_CHICK Isoform 1 of Tropomodulin 3 OS=Gallus gallus OX=9031 GN=TMOD3 PE=1 SV=1 CANONICAL=A0A8V0ZMW6-1" }, "locus": { "chromosome": "10", "start_pos": 9052606, "end_pos": 9035706, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057111.1", "url": "https://www.ensembl.org/id/ENSGALT00010057111.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034741.1", "url": "https://www.ensembl.org/id/ENSGALP00010034741.1" } ] } }, { "isoform_ac": "A0A8V0ZT40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW6/entry#A0A8V0ZT40-1", "sequence": { "sequence": "MTLPFRKDLDKYKDLDEDDILGKLSEEELKQLETVLDDLDPENALLPAGFRQKDQTAKKASGPFDRERLLAYLEKQALEHKDREDYVPFTKEKKGKVFIPKQKPAQSYAEEKIALDPELEEALTSATDTELCDLAAILGMSNLITNNQFCDIVGSSNGVGKDSFSNIVKGEKMLPVFDEPPNPTNVEETLQRIKDNDSRLVEVNLNNIKNIPIPTLKEFAKALETNTHVKNFSLAATRSNDPVAVALADMLRVNTKLKSLNIESNFITGVGILALVDALKDNETLTEIKIDNQRQQLGTLAEVEIAKMLEENTKILKFGYHFTQQGPRARAAAAITKNNDLVKRRAVYLNRIAFYNSVSLTFVGLDAL", "length": 368, "header": "tr|A0A8V0ZT40-1|A0A8V0ZMW6_CHICK Computationally mapped isoform of Tropomodulin 3 OS=Gallus gallus OX=9031 GN=TMOD3 PE=1 SV=1 CANONICAL=A0A8V0ZMW6-1" }, "locus": { "chromosome": "10", "start_pos": 9052606, "end_pos": 9036935, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057101.1", "url": "https://www.ensembl.org/id/ENSGALT00010057101.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034733.1", "url": "https://www.ensembl.org/id/ENSGALP00010034733.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-390522", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390522", "resource": "Reactome", "description": "Striated Muscle Contraction" }, { "id": "R-GGA-9013418", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013418", "resource": "Reactome", "description": "RHOBTB2 GTPase cycle" }, { "id": "R-GGA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW6", 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"glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJM7-1", "uniprot_ac": "A0A8V0ZJM7", "uniprot_id": "A0A8V0ZJM7_CHICK", "mass": { "chemical_mass": 54557.0, "monoisotopic_mass": 54557.0 }, "refseq": {}, "gene_names": [ { "name": "BTBD10", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7" } ] } ], "protein_names": [ { "name": "BTB domain containing 10", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BTBD10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7", "locus": { "chromosome": "5", "start_pos": 7234259, "end_pos": 7208100, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021681", "url": "https://www.ensembl.org/id/ENSGALG00010021681" } ] } } ], "crossref": [ { "id": "A0A8V0ZJM7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005369", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005369", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18385", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18385", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423029", "url": "https://www.ncbi.nlm.nih.gov/gene/423029", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423029", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423029", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HNSERDG", "url": "https://omabrowser.org/oma/group/HNSERDG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P2C7", "url": "https://www.orthodb.org/?gene=A0A1D5P2C7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJM7", "url": "https://www.orthodb.org/?gene=A0A8V0ZJM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLB8", "url": "https://www.orthodb.org/?gene=A0A8V0ZLB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLI0", "url": "https://www.orthodb.org/?gene=A0A8V0ZLI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS32", "url": "https://www.orthodb.org/?gene=A0A8V0ZS32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C8S4", "url": "https://www.orthodb.org/?gene=E1C8S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "R4GI02", "url": "https://www.orthodb.org/?gene=R4GI02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21637", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21637", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21637:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21637:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P2C7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P2C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P2C7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8S4", "url": "https://www.uniprot.org/uniprotkb/E1C8S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C8S4-1", "url": "https://www.uniprot.org/uniprotkb/E1C8S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI02", "url": "https://www.uniprot.org/uniprotkb/R4GI02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "R4GI02-1", "url": "https://www.uniprot.org/uniprotkb/R4GI02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEEKDADLAFRAVFLEGTEFLCALIPKLFPCFCVSSLIDTRGSTSSRIAKGVDCTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQYHSDREKDHSSSRPSSPRPQKTSPNGSSVSMGNSSRNSSQSSSDGSCKAGGEMVFVYENGKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGVIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARKQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPPSNSEMDTEGQNPPL", "length": 484, "header": "tr|A0A8V0ZJM7-1|A0A8V0ZJM7_CHICK Isoform 1 of BTB domain containing 10 OS=Gallus gallus OX=9031 GN=BTBD10 PE=4 SV=1 CANONICAL=A0A8V0ZJM7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P2C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7/entry#A0A1D5P2C7-1", "sequence": { "sequence": "MLCTSSRIAKGVDCTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQYHSDREKDHSSSRPSSPRPQKTSPNGSSVSMGNSSRNSSQSSSDGSCKAGGEMVFVYENGKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGVIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARKQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPPSNSEMDTEGQNPPL", "length": 443, "header": "tr|A0A1D5P2C7-1|A0A8V0ZJM7_CHICK Computationally mapped isoform of BTB domain containing 10 OS=Gallus gallus OX=9031 GN=BTBD10 PE=4 SV=2 CANONICAL=A0A8V0ZJM7-1" }, "locus": { "chromosome": "5", "start_pos": 7232595, "end_pos": 7215462, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052684.1", "url": "https://www.ensembl.org/id/ENSGALT00010052684.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031590.1", "url": "https://www.ensembl.org/id/ENSGALP00010031590.1" } ] } }, { "isoform_ac": "A0A8V0ZJM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7/entry#A0A8V0ZJM7-1", "sequence": { "sequence": "MMEEKDADLAFRAVFLEGTEFLCALIPKLFPCFCVSSLIDTRGSTSSRIAKGVDCTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQYHSDREKDHSSSRPSSPRPQKTSPNGSSVSMGNSSRNSSQSSSDGSCKAGGEMVFVYENGKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGVIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARKQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPPSNSEMDTEGQNPPL", "length": 484, "header": "tr|A0A8V0ZJM7-1|A0A8V0ZJM7_CHICK Isoform 1 of BTB domain containing 10 OS=Gallus gallus OX=9031 GN=BTBD10 PE=4 SV=1 CANONICAL=A0A8V0ZJM7-1" }, "locus": { "chromosome": "5", "start_pos": 7232595, "end_pos": 7219897, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052669.1", "url": "https://www.ensembl.org/id/ENSGALT00010052669.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031574.1", "url": "https://www.ensembl.org/id/ENSGALP00010031574.1" } ] } }, { "isoform_ac": "A0A8V0ZLB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7/entry#A0A8V0ZLB8-1", "sequence": { "sequence": "MSVCSWCPYLLAGFHSTSSRIAKGVDCTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQYHSDREKDHSSSRPSSPRPQKTSPNGSSVSMGNSSRNSSQSSSDGSCKAGGEMVFVYENGKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGVIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARKQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPPSNSEMDTEGQNPPL", "length": 456, "header": "tr|A0A8V0ZLB8-1|A0A8V0ZLB8_CHICK Computationally mapped isoform of BTB domain containing 10 OS=Gallus gallus OX=9031 GN=BTBD10 PE=4 SV=1 CANONICAL=A0A8V0ZJM7-1" }, "locus": { "chromosome": "5", "start_pos": 7232595, "end_pos": 7208876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052691.1", "url": "https://www.ensembl.org/id/ENSGALT00010052691.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031597.1", "url": "https://www.ensembl.org/id/ENSGALP00010031597.1" } ] } }, { "isoform_ac": "A0A8V0ZLI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7/entry#A0A8V0ZLI0-1", "sequence": { "sequence": "MLTEQQLRFKQRVMNIFIDSTSSRIAKGVDCTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQYHSDREKDHSSSRPSSPRPQKTSPNGSSVSMGNSSRNSSQSSSDGSCKAGGEMVFVYENGKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGVIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARKQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPPSNSEMDTEGQNPPL", "length": 460, "header": "tr|A0A8V0ZLI0-1|A0A8V0ZLI0_CHICK Computationally mapped isoform of BTB domain containing 10 OS=Gallus gallus OX=9031 GN=BTBD10 PE=4 SV=1 CANONICAL=A0A8V0ZJM7-1" }, "locus": { "chromosome": "5", "start_pos": 7232595, "end_pos": 7217465, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052679.1", "url": "https://www.ensembl.org/id/ENSGALT00010052679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031585.1", "url": "https://www.ensembl.org/id/ENSGALP00010031585.1" } ] } }, { "isoform_ac": "A0A8V0ZS32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7/entry#A0A8V0ZS32-1", "sequence": { "sequence": "MEWLMQSSCFCTSSRIAKGVDCTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQYHSDREKDHSSSRPSSPRPQKTSPNGSSVSMGNSSRNSSQSSSDGSCKAGGEMVFVYENGKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGVIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARKQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPPSNSEMDTEGQNPPL", "length": 451, "header": "tr|A0A8V0ZS32-1|A0A8V0ZJM7_CHICK Computationally mapped isoform of BTB domain containing 10 OS=Gallus gallus OX=9031 GN=BTBD10 PE=4 SV=1 CANONICAL=A0A8V0ZJM7-1" }, "locus": { "chromosome": "5", "start_pos": 7232595, "end_pos": 7215540, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052682.1", "url": "https://www.ensembl.org/id/ENSGALT00010052682.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031588.1", "url": "https://www.ensembl.org/id/ENSGALP00010031588.1" } ] } }, { "isoform_ac": "E1C8S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7/entry#E1C8S4-1", "sequence": { "sequence": "MPKDADLAFRAVFLEGTEFLCALIPKLFPCFCVSSLIDTRGSTSSRIAKGVDCTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQYHSDREKDHSSSRPSSPRPQKTSPNGSSVSMGNSSRNSSQSSSDGSCKAGGEMVFVYENGKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGVIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARKQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPPSNSEMDTEGQNPPL", "length": 482, "header": "tr|E1C8S4-1|A0A8V0ZJM7_CHICK Computationally mapped isoform of BTB domain containing 10 OS=Gallus gallus OX=9031 GN=BTBD10 PE=4 SV=2 CANONICAL=A0A8V0ZJM7-1" }, "locus": { "chromosome": "5", "start_pos": 7232595, "end_pos": 7219986, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052674.1", "url": "https://www.ensembl.org/id/ENSGALT00010052674.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031580.1", "url": "https://www.ensembl.org/id/ENSGALP00010031580.1" } ] } }, { "isoform_ac": "R4GI02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7/entry#R4GI02-1", "sequence": { "sequence": "MAGRPHPYDSNSSDPENWDRKLHNRPRKLCKHSSTSSRIAKGVDCTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQYHSDREKDHSSSRPSSPRPQKTSPNGSSVSMGNSSRNSSQSSSDGSCKAGGEMVFVYENGKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGVIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARKQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPPSNSEMDTEGQNPPL", "length": 474, "header": "tr|R4GI02-1|A0A8V0ZJM7_CHICK Computationally mapped isoform of BTB domain containing 10 OS=Gallus gallus OX=9031 GN=BTBD10 PE=4 SV=3 CANONICAL=A0A8V0ZJM7-1" }, "locus": { "chromosome": "5", "start_pos": 7232595, "end_pos": 7214431, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052688.1", "url": "https://www.ensembl.org/id/ENSGALT00010052688.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031594.1", "url": "https://www.ensembl.org/id/ENSGALP00010031594.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423029", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423029", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3I057-1", "protein_name": "BTB/POZ domain-containing protein 10 isoform X1", "gene_name": "Btbd10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGRPHPYDSNSSDPENWDRKLHSRPRKLYKHSSTASRVAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQRASPNGSMSSAGNSSRNSSQSSSDGSCKTSGEMVFVYENAKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPSHPASGSNDLDPDAQNPML", "length": 475 }, "evidence": [ { "id": "A0A8V0ZJM7", "url": "https://omabrowser.org/oma/group/A0A8V0ZJM7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "X1WDG9-1", "protein_name": "BTB/POZ domain-containing protein 10", "gene_name": "btbd10b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNMHGASGGCDRSRDRRRSSDRSRDSSHERGEGQLTPCIRNVTSPTRQHNSEREGGSSRPSSPRPQRISPSSSSSSGVASSRNSSLSSSEGTYKSMVPGEMVFVYENVKDGTRSVRTSEKVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGISSTVFRAILDYYKSGIIRCPDGISIPELREACDYLCISFDYSTIKCRDLSALMHELSNDGARRQFEFYLEEMVLPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKDRGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMNPGPQVDELDILPNHPPPGHHYSNNFNNEPDSDAPSPAV", "length": 434 }, "evidence": [ { "id": "A0A8V0ZJM7", "url": "https://omabrowser.org/oma/group/A0A8V0ZJM7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0051897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 138, "end_pos": 140, "annotation": 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"label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 138, "end_pos": 140 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ] }, { "name": "NYGGF4", "type": "synonym", "evidence": [ { "id": "XP_046754340", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754340" } ] }, { "name": "PID1", "type": "synonym", "evidence": [ { "id": "XP_046754340", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754340" } ] } ], "protein_names": [ { "name": "PTB-containing, cubilin and LRP1-interacting protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9/entry#names_and_taxonomy" } ] }, { "name": "PTB-containing, cubilin and LRP1-interacting protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046754340", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754340" } ] }, { "name": "Phosphotyrosine interaction domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046754340", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046754340" } ] }, { "annotation": "Increases proliferation of preadipocytes without affecting adipocytic differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7N1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7N1#function" }, { "database": "UniProtKB", "id": "ARBA00054486", "url": "https://www.uniprot.org/uniprotkb/ARBA00054486#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP4#function" }, { "database": "UniProtKB", "id": "A0A8V0ZZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZG4#function" }, { "database": "UniProtKB", "id": "A0A8V0ZRY2", "url": 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} ], "sequence": { "sequence": "MASLCSVRGCGSPGGWSQATVTLACIVGLQCTLPFCFLQKDNLLSMAADIQPVYKIQTSCWRELHLQQTAVPDGPSRPSAVVGHQQHFQTMLKTKLNVLTLRKEPLPTVIFHEPEAIELCTTTPLMKTRAHTGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDIYPANALLEIRPFQVWLHHLDLKGEATVHMDTFQVARIAYCTADHNISPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFKKTFHSMKSDGRIHRNSSSEEVSHGFESDDG", "length": 293, "header": "tr|A0A8V0ZLN9-1|A0A8V0ZLN9_CHICK Isoform 1 of PTB-containing, cubilin and LRP1-interacting protein OS=Gallus gallus OX=9031 GN=PID1 PE=4 SV=1 CANONICAL=A0A8V0ZLN9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P7N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9/entry#A0A1D5P7N1-1", "sequence": { "sequence": "MWQPATERLQHFQTMLKTKLNVLTLRKEPLPTVIFHEPEAIELCTTTPLMKTRAHTGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDIYPANALLEIRPFQVWLHHLDLKGEATVHMDTFQVARIAYCTADHNISPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFKKTFHSMKSDGRIHRNSSSEEVSHGFESDDG", "length": 217, "header": "tr|A0A1D5P7N1-1|A0A8V0ZLN9_CHICK Computationally mapped isoform of PTB-containing, cubilin and LRP1-interacting protein OS=Gallus gallus OX=9031 GN=PID1 PE=4 SV=1 CANONICAL=A0A8V0ZLN9-1" }, "locus": { "chromosome": "9", "start_pos": 9590513, "end_pos": 9513541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056554.1", "url": "https://www.ensembl.org/id/ENSGALT00010056554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034296.1", "url": "https://www.ensembl.org/id/ENSGALP00010034296.1" } ] } }, { "isoform_ac": "A0A8V0ZLN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9/entry#A0A8V0ZLN9-1", "sequence": { "sequence": "MASLCSVRGCGSPGGWSQATVTLACIVGLQCTLPFCFLQKDNLLSMAADIQPVYKIQTSCWRELHLQQTAVPDGPSRPSAVVGHQQHFQTMLKTKLNVLTLRKEPLPTVIFHEPEAIELCTTTPLMKTRAHTGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDIYPANALLEIRPFQVWLHHLDLKGEATVHMDTFQVARIAYCTADHNISPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFKKTFHSMKSDGRIHRNSSSEEVSHGFESDDG", "length": 293, "header": "tr|A0A8V0ZLN9-1|A0A8V0ZLN9_CHICK Isoform 1 of PTB-containing, cubilin and LRP1-interacting protein OS=Gallus gallus OX=9031 GN=PID1 PE=4 SV=1 CANONICAL=A0A8V0ZLN9-1" }, "locus": { "chromosome": "9", "start_pos": 9561956, "end_pos": 9513541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056544.1", "url": "https://www.ensembl.org/id/ENSGALT00010056544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034286.1", "url": "https://www.ensembl.org/id/ENSGALP00010034286.1" } ] } }, { "isoform_ac": "A0A8V0ZLP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9/entry#A0A8V0ZLP4-1", "sequence": { "sequence": "MGRRGKSWKAARSRPLGVLQSDKRLNSNVHFQTMLKTKLNVLTLRKEPLPTVIFHEPEAIELCTTTPLMKTRAHTGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDIYPANALLEIRPFQVWLHHLDLKGEATVHMDTFQVARIAYCTADHNISPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFKKTFHSMKSDGRIHRNSSSEEVSHGFESDDG", "length": 236, "header": "tr|A0A8V0ZLP4-1|A0A8V0ZLP4_CHICK Computationally mapped isoform of PTB-containing, cubilin and LRP1-interacting protein OS=Gallus gallus OX=9031 GN=PID1 PE=4 SV=1 CANONICAL=A0A8V0ZLN9-1" }, "locus": { "chromosome": "9", "start_pos": 9588972, "end_pos": 9513541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056550.1", "url": "https://www.ensembl.org/id/ENSGALT00010056550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034292.1", "url": "https://www.ensembl.org/id/ENSGALP00010034292.1" } ] } }, { "isoform_ac": "A0A8V0ZRY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9/entry#A0A8V0ZRY2-1", "sequence": { "sequence": "MLQGRHPRLHTARGHFQTMLKTKLNVLTLRKEPLPTVIFHEPEAIELCTTTPLMKTRAHTGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDIYPANALLEIRPFQVWLHHLDLKGEATVHMDTFQVARIAYCTADHNISPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFKKTFHSMKSDGRIHRNSSSEEVSHGFESDDG", "length": 221, "header": "tr|A0A8V0ZRY2-1|A0A8V0ZLN9_CHICK Computationally mapped isoform of PTB-containing, cubilin and LRP1-interacting protein OS=Gallus gallus OX=9031 GN=PID1 PE=4 SV=1 CANONICAL=A0A8V0ZLN9-1" }, "locus": { "chromosome": "9", "start_pos": 9589576, "end_pos": 9513541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056552.1", "url": "https://www.ensembl.org/id/ENSGALT00010056552.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034294.1", "url": "https://www.ensembl.org/id/ENSGALP00010034294.1" } ] } }, { "isoform_ac": "A0A8V0ZTX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9/entry#A0A8V0ZTX5-1", "sequence": { "sequence": "MREHFQTMLKTKLNVLTLRKEPLPTVIFHEPEAIELCTTTPLMKTRAHTGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDIYPANALLEIRPFQVWLHHLDLKGEATVHMDTFQVARIAYCTADHNISPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFKKTFHSMKSDGRIHRNSSSEEVSHGFESDDG", "length": 210, "header": "tr|A0A8V0ZTX5-1|A0A8V0ZLN9_CHICK Computationally mapped isoform of PTB-containing, cubilin and LRP1-interacting protein OS=Gallus gallus OX=9031 GN=PID1 PE=4 SV=1 CANONICAL=A0A8V0ZLN9-1" }, "locus": { "chromosome": "9", "start_pos": 9561281, "end_pos": 9513541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056543.1", "url": "https://www.ensembl.org/id/ENSGALT00010056543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034285.1", "url": "https://www.ensembl.org/id/ENSGALP00010034285.1" } ] } }, { "isoform_ac": "A0A8V0ZZF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9/entry#A0A8V0ZZF4-1", "sequence": { "sequence": "MDSVFYKHFQTMLKTKLNVLTLRKEPLPTVIFHEPEAIELCTTTPLMKTRAHTGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDIYPANALLEIRPFQVWLHHLDLKGEATVHMDTFQVARIAYCTADHNISPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFKKTFHSMKSDGRIHRNSSSEEVSHGFESDDG", "length": 214, "header": "tr|A0A8V0ZZF4-1|A0A8V0ZLN9_CHICK Computationally mapped isoform of PTB-containing, cubilin and LRP1-interacting protein OS=Gallus gallus OX=9031 GN=PID1 PE=4 SV=1 CANONICAL=A0A8V0ZLN9-1" }, "locus": { "chromosome": "9", "start_pos": 9581560, "end_pos": 9513541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056546.1", "url": "https://www.ensembl.org/id/ENSGALT00010056546.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034288.1", "url": "https://www.ensembl.org/id/ENSGALP00010034288.1" } ] } }, { "isoform_ac": "A0A8V0ZZG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9/entry#A0A8V0ZZG4-1", "sequence": { "sequence": "MWQPATERLQKDNLLSMAADIQPVYKIQTSCWRELHLQQTAVPDGPSRPSAVVGHQQHFQTMLKTKLNVLTLRKEPLPTVIFHEPEAIELCTTTPLMKTRAHTGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDIYPANALLEIRPFQVWLHHLDLKGEATVHMDTFQVARIAYCTADHNISPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFKKTFHSMKSDGRIHRNSSSEEVSHGFESDDG", "length": 264, "header": "tr|A0A8V0ZZG4-1|A0A8V0ZLN9_CHICK Computationally mapped isoform of PTB-containing, cubilin and LRP1-interacting protein OS=Gallus gallus OX=9031 GN=PID1 PE=4 SV=1 CANONICAL=A0A8V0ZLN9-1" }, "locus": { "chromosome": "9", "start_pos": 9590513, "end_pos": 9513541, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056556.1", "url": "https://www.ensembl.org/id/ENSGALT00010056556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034298.1", "url": "https://www.ensembl.org/id/ENSGALP00010034298.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424787", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424787", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 19, "go_terms": [ { "name": "negative regulation of insulin receptor signaling pathway", "id": "GO:0046627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046627", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "regulation of mitochondrial membrane potential", "id": "GO:0051881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051881", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "regulation of reactive oxygen species metabolic process", "id": "GO:2000377", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000377", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "negative regulation of D-glucose import", "id": "GO:0046325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "regulation of ATP biosynthetic process", "id": "GO:2001169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001169", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "positive regulation of biosynthetic process", "id": "GO:0009891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "positive regulation of ATP biosynthetic process", "id": "GO:2001171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "positive regulation of reactive oxygen species metabolic process", "id": "GO:2000379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000379", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "negative regulation of protein localization to plasma membrane", "id": "GO:1903077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903077", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "negative regulation of ATP biosynthetic process", "id": "GO:2001170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "cellular response to interleukin-6", "id": "GO:0071354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071354", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" } ], "pmid": "" }, { "name": "cellular response to fatty acid", "id": "GO:0071398", "url": 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"" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN9" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 206, "end_pos": 266, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLX7-1", "uniprot_ac": "A0A8V0ZLX7", "uniprot_id": "A0A8V0ZLX7_CHICK", "mass": { "chemical_mass": 181068.0, "monoisotopic_mass": 181068.0 }, "refseq": {}, "gene_names": [ { "name": "RIMBP2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7" } ] } ], "protein_names": [ { "name": "RIMS binding protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PLA7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLA7#function" }, { "database": "UniProtKB", "id": "ARBA00054159", "url": "https://www.uniprot.org/uniprotkb/ARBA00054159#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX3#function" }, { "database": "UniProtKB", "id": "A0A8V0ZZP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZP8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZS42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS42#function" }, { "database": "UniProtKB", "id": "A0A8V0ZS47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS47#function" }, { "database": "UniProtKB", "id": "A0A8V0ZV88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV88#function" }, { "database": "UniProtKB", "id": "A0A8V0ZV93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV93#function" }, { "database": "UniProtKB", "id": "A0A8V0ZV99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV99#function" }, { "database": "UniProtKB", "id": "A0A8V0ZVA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVA5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RIMBP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7", "locus": { "chromosome": "15", "start_pos": 3353294, "end_pos": 3232638, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023212", "url": "https://www.ensembl.org/id/ENSGALG00010023212" } ] } } ], "crossref": [ { "id": "ENSGALG00000002579", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002579", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12013", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12013", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12014", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12014", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374105", "url": "https://www.ncbi.nlm.nih.gov/gene/374105", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PLA7", "url": "https://www.orthodb.org/?gene=A0A1D5PLA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLX3", "url": "https://www.orthodb.org/?gene=A0A8V0ZLX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLX7", "url": "https://www.orthodb.org/?gene=A0A8V0ZLX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS42", "url": "https://www.orthodb.org/?gene=A0A8V0ZS42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS47", "url": "https://www.orthodb.org/?gene=A0A8V0ZS47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV88", "url": "https://www.orthodb.org/?gene=A0A8V0ZV88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV93", "url": "https://www.orthodb.org/?gene=A0A8V0ZV93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV99", "url": "https://www.orthodb.org/?gene=A0A8V0ZV99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVA5", "url": "https://www.orthodb.org/?gene=A0A8V0ZVA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZP8", "url": "https://www.orthodb.org/?gene=A0A8V0ZZP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14234:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14234:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PLA7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PLA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PLA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKAISHILDHDYSVLDSPKANQSFPKAAKSLIKDQEEDKVSKKGNKKAKQTSEKLPHFRPEDGSRQKGSSVTAKKSKDVSPSTSLILPSNNSAVITKTITRTFPFKQKMHLVNAKAHHLQNINKQSKRIKDVEIQMLQVEREELKNQLGCLREGLMGQKPGNTEELLKQSQKELLWLQRQLSLISTGSSMCVLAANKFGNDPSCLQSATSECTSDQVEFIEETWISKSHVTTLNQEYHHWQYSKNELKDAVQEKNRLSLQYAIVSHKALQYDQVKSDYDHLRETLIRVTKERDLAVKGKHQLQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIELLQKAQVEAKKEHEGAVQLLEAKVRELEEKCRTQSEQFNLLSRELEKFRQQAGKIDLLSSNPLTSSDISGSPSKSLSQLMNGIATSLGKGHESPSGSRCVISEFIRPLQISGDKPEQLSVKPTFLSKSRSDTPRCRFDSDMDNDQNSNTSKQRYSGKVHLCIARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNETRLSSTLSSEQDQNFINHSGSTLEGDILEISPPSHIDSSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSWLPTNSNYSHVIFLNEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKPPALTATGTSHGANVTGYGVYAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDSSVAAIPSDLLVPPSPHPRTAPKSKPLASAGAPETKEEHLGPHLKIDESWEQTHSASPVHGHTLEPPVPNFHSSLQGRRSPSPNRILPQPQGTPVPNTVAKAMAREAAQRVAESNRMERRSVFSERSNAAQYANSDDEEDGYDSPNVKRRGASVDDFLKGSELGKQPHYCHGEDYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRVSLTSHNALKECNKNKTTDATFLEQPDFSQQIHHSKKLFSIPEVAEEDGEYSELLYKQGLGMPYKKKSTIARDSRPPRPYNQDQQHNFWYPAKHRISGMEDFTADDKGCKYSRSLSRSPDSGLDCGSEEEESRFTFRYTCDSVSANVASSCCADTADCSCRKSMRPLLARRKTLTRQTSIEEDFGDLGSSFVEPRSEQVKSSYEKKYETQKCNRTDNLSNEDIQGGWKNDLKMADSRAAGPLAKSSHRDAEDSLLLGNPSSAGRPERVEHAGRRSSHGSAVPQRSRPMLVPSIEITMDSNSEGGRSRSGSEGNISPVKEEAYYRSIGGHKKWPQQRTMASEYRYDGYGGHDHLSPDIYEESETDPGTEDISTRIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCTRIGLIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYDPRESSPNVDVEVFT", "length": 1618, "header": "tr|A0A8V0ZLX7-1|A0A8V0ZLX7_CHICK Isoform 1 of RIMS binding protein 2 OS=Gallus gallus OX=9031 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A8V0ZLX7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PLA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7/entry#A0A1D5PLA7-1", "sequence": { "sequence": "MREAAERRQQLELEHEQALAVLNAKQQEIELLQKAQVEAKKEHEGAVQLLEAKVRELEEKCRTQSEQFNLLSRELEKFRQQAGKIDLLSSNPLTSSDISGSPSKSLSQLMNGIATSLGKGHESPSGSRCVISEFIRPLQISGDKPEQLSVKPTFLSKSRSDTPRCRFDSDMDNDQNSNTSKQRYSGKVHLCIARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNETRLSSTLSSEQDQNFINHSGSTLEGDILEISPPSHIDSSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSWLPTNSNYSHVIFLNEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKPPALTATGTSHGANVTGYGVYAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDSSVAAIPSDLLVPPSPHPRTAPKSKPLASAGAPETKEEHLGPHLKIDESWEQTHSASPVHGHTLEPPVPNFHSSLQGRRSPSPNRILPQPQGTPVPNTVAKAMAREAAQRVAESNRMERRSVFSERSNAAQYANSDDEEDGYDSPNVKRRGASVDDFLKGSELGKQPHYCHGEDYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRVSLTSHNALKECNKNKTTDATFLEQPDFSQQIHHSKKLFSIPEVAEEDGEYSELLYKQGLGMPYKKKSTIARDSRPPRPYNQDQQHNFWYPAKHRISGMEDFTADDKGCKYSRSLSRSPDSGLDCGSEEEESRFTFRYTCDSVSANVASSCCADTADCSCRKSMRPLLARRKTLTRQTSIEEDFGDLGSSFVEPRSEQVKSSYEKKYETQKCNRTDNLSNEDIQGGWKNDLKMADSRAAGPLAKSSHRDAEDSLLLGNPSSAGRPERVEHAGRRSSHGSAVPQRSRPMLVPSIDGYGGHDHLSPDIYEESETDPGTEDISTRIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCTRIGLIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSRYLHDTPIRTKAKRVPPENTGTSRRAPSPTVHLHSGSPTSPMGSGSPGRGRDMSSKKKKGLLSKGKKLLKKLGAVK", "length": 1379, "header": "tr|A0A1D5PLA7-1|A0A8V0ZLX7_CHICK Computationally mapped isoform of RIMS binding protein 2 OS=Gallus gallus OX=9031 GN=RIMBP2 PE=3 SV=2 CANONICAL=A0A8V0ZLX7-1" }, "locus": { "chromosome": "15", "start_pos": 3353138, "end_pos": 3309444, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056626.1", "url": "https://www.ensembl.org/id/ENSGALT00010056626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034368.1", "url": "https://www.ensembl.org/id/ENSGALP00010034368.1" } ] } }, { "isoform_ac": "A0A8V0ZLX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7/entry#A0A8V0ZLX3-1", "sequence": { "sequence": "MHLVNAKAHHLQNINKQSKRIKDVEIQMLQVEREELKNQLGCLREGLMGQKPGNTEELLKQSQKELLWLQRQLSLISTGSSMCVLAANKFGNDPSCLQSATSECTSDQVEFIEETWISKSHVTTLNQEYHHWQYSKNELKDAVQEKNRLSLQYAIVSHKALQYDQVKSDYDHLRETLIRVTKERDLAVKGKHQLQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIELLQKAQVEAKKEHEGAVQLLEAKVRELEEKCRTQSEQFNLLSRELEKFRQQAGKIDLLSSNPLTSSDISGSPSKSLSQLMNGIATSLGKGHESPSGSRCVISEFIRPLQISGDKPEQLSVKPTFLSKSRSDTPRCRFDSDMDNDQNSNTSKQRYSGKVHLCIARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNETRLSSTLSSEQDQNFINHSGSTLEGDILEISPPSHIDSSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSWLPTNSNYSHVIFLNEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKPPALTATGTSHGANVTGYGVYAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDSSVAAIPSDLLVPPSPHPRTAPKSKPLASAGAPETKEEHLGPHLKIDESWEQTHSASPVHGHTLEPPVPNFHSSLQGRRSPSPNRILPQPQGTPVPNTVAKAMAREAAQRVAESNRMERRSVFSERSNAAQYANSDDEEDGYDSPNVKRRGASVDDFLKGSELGKQPHYCHGEDYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRVSLTSHNALKLLGNPSSAGRPERVEHAGRRSSHGSAVPQRSRPMLVPSIEITMDSNSEGGRSRSGSEGNISPVKEEAYYRSIGGHKKWPQQRTMASEYRYDGYGGHDHLSPDIYEESETDPGTEDISTRIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCTRIGLIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSRYLHDTPIRTKAKRVSNKVLQT", "length": 1339, "header": "tr|A0A8V0ZLX3-1|A0A8V0ZLX3_CHICK Computationally mapped isoform of RIMS-binding protein 2 OS=Gallus gallus OX=9031 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A8V0ZLX7-1" }, "locus": { "chromosome": "15", "start_pos": 3350589, "end_pos": 3244124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056631.1", "url": "https://www.ensembl.org/id/ENSGALT00010056631.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034372.1", "url": "https://www.ensembl.org/id/ENSGALP00010034372.1" } ] } }, { "isoform_ac": "A0A8V0ZLX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7/entry#A0A8V0ZLX7-1", "sequence": { "sequence": "MKKAISHILDHDYSVLDSPKANQSFPKAAKSLIKDQEEDKVSKKGNKKAKQTSEKLPHFRPEDGSRQKGSSVTAKKSKDVSPSTSLILPSNNSAVITKTITRTFPFKQKMHLVNAKAHHLQNINKQSKRIKDVEIQMLQVEREELKNQLGCLREGLMGQKPGNTEELLKQSQKELLWLQRQLSLISTGSSMCVLAANKFGNDPSCLQSATSECTSDQVEFIEETWISKSHVTTLNQEYHHWQYSKNELKDAVQEKNRLSLQYAIVSHKALQYDQVKSDYDHLRETLIRVTKERDLAVKGKHQLQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIELLQKAQVEAKKEHEGAVQLLEAKVRELEEKCRTQSEQFNLLSRELEKFRQQAGKIDLLSSNPLTSSDISGSPSKSLSQLMNGIATSLGKGHESPSGSRCVISEFIRPLQISGDKPEQLSVKPTFLSKSRSDTPRCRFDSDMDNDQNSNTSKQRYSGKVHLCIARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNETRLSSTLSSEQDQNFINHSGSTLEGDILEISPPSHIDSSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSWLPTNSNYSHVIFLNEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKPPALTATGTSHGANVTGYGVYAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDSSVAAIPSDLLVPPSPHPRTAPKSKPLASAGAPETKEEHLGPHLKIDESWEQTHSASPVHGHTLEPPVPNFHSSLQGRRSPSPNRILPQPQGTPVPNTVAKAMAREAAQRVAESNRMERRSVFSERSNAAQYANSDDEEDGYDSPNVKRRGASVDDFLKGSELGKQPHYCHGEDYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRVSLTSHNALKECNKNKTTDATFLEQPDFSQQIHHSKKLFSIPEVAEEDGEYSELLYKQGLGMPYKKKSTIARDSRPPRPYNQDQQHNFWYPAKHRISGMEDFTADDKGCKYSRSLSRSPDSGLDCGSEEEESRFTFRYTCDSVSANVASSCCADTADCSCRKSMRPLLARRKTLTRQTSIEEDFGDLGSSFVEPRSEQVKSSYEKKYETQKCNRTDNLSNEDIQGGWKNDLKMADSRAAGPLAKSSHRDAEDSLLLGNPSSAGRPERVEHAGRRSSHGSAVPQRSRPMLVPSIEITMDSNSEGGRSRSGSEGNISPVKEEAYYRSIGGHKKWPQQRTMASEYRYDGYGGHDHLSPDIYEESETDPGTEDISTRIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCTRIGLIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYDPRESSPNVDVEVFT", "length": 1618, "header": "tr|A0A8V0ZLX7-1|A0A8V0ZLX7_CHICK Isoform 1 of RIMS binding protein 2 OS=Gallus gallus OX=9031 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A8V0ZLX7-1" }, "locus": { "chromosome": "15", "start_pos": 3348207, "end_pos": 3232837, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056635.1", "url": "https://www.ensembl.org/id/ENSGALT00010056635.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034377.1", "url": "https://www.ensembl.org/id/ENSGALP00010034377.1" } ] } }, { "isoform_ac": "A0A8V0ZS42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7/entry#A0A8V0ZS42-1", "sequence": { "sequence": "MREAAERRQQLELEHEQALAVLNAKQQEIELLQKVIKCLCSVLLMQAKVRELEEKCRTQSEQFNLLSRELEKFRQQAGKIDLLSSNPLTSSDISGSPSKSLSQLMNGIATSLGKGHESPSGSRCVISEFIRPLQISGDKPEQLSVKPTFLSKSRSDTPRCRFDSDMDNDQNSNTSKQRYSGKVHLCIARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNETRLSSTLSSEQDQNFINHSGSTLEGDILEISPPSHIDSSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSWLPTNSNYSHVIFLNEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKPPALTATGTSHGANVTGYGVYAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDSSVAAIPSDLLVPPSPHPRTAPKSKPLASAGAPETKEEHLGPHLKIDESWEQTHSASPVHGHTLEPPVPNFHSSLQGRRSPSPNRILPQPQGTPVPNTVAKAMAREAAQRVAESNRMERRSVFSERSNAAQYANSDDEEDGYDSPNVKRRGASVDDFLKGSELGKQPHYCHGEDYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRVSLTSHNALKECNKNKTTDATFLEQPDFSQQIHHSKKLFSIPEVAEEDGEYSELLYKQGLGMPYKKKSTIARDSRPPRPYNQDQQHNFWYPAKHRISGMEDFTADDKGCKYSRSLSRSPDSGLDCGSEEEESRFTFRYTCDSVSANVASSCCADTADCSCRKSMRPLLARRKTLTRQTSIEEDFGDLGSSFVEPRSEQVKSSYEKKYETQKCNRTDNLSNEDIQGGWKNDLKMADSRAAGPLAKSSHRDAEDSLLLGNPSSAGRPERVEHAGRRSSHGSAVPQRSRPMLVPSIDGYGGHDHLSPDIYEESETDPGTEDISTRIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCTRIGLIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSRYLHDTPIRTKAKRKKSVHFTP", "length": 1320, "header": "tr|A0A8V0ZS42-1|A0A8V0ZLX7_CHICK Computationally mapped isoform of RIMS binding protein 2 OS=Gallus gallus OX=9031 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A8V0ZLX7-1" }, "locus": { "chromosome": "15", "start_pos": 3351147, "end_pos": 3309444, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056617.1", "url": "https://www.ensembl.org/id/ENSGALT00010056617.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034359.1", "url": "https://www.ensembl.org/id/ENSGALP00010034359.1" } ] } }, { "isoform_ac": "A0A8V0ZS47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7/entry#A0A8V0ZS47-1", "sequence": { "sequence": "MKNELKDAVQEKNRLSLQYAIVSHKALQYDQVKSDYDHLRETLIRVTKERDLAVKGKHQLQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIELLQKAQVEAKKEHEGAVQLLEAKVRELEEKCRTQSEQFNLLSRELEKFRQQAGKIDLLSSNPLTSSDISGSPSKSLSQLMNGIATSLGKGHESPSGSRCVISEFIRPLQISGDKPEQLSVKPTFLSKSRSDTPRCRFDSDMDNDQNSNTSKQRYSGKVHLCIARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNETRLSSTLSSEQDQNFINHSGSTLEGDILEISPPSHIDSSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSWLPTNSNYSHVIFLNEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKPPALTATGTSHGANVTGYGVYAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDSSVAAIPSDLLVPPSPHPRTAPKSKPLASAGAPETKEEHLGPHLKIDESWEQTHSASPVHGHTLEPPVPNFHSSLQGRRSPSPNRILPQPQGTPVPNTVAKAMAREAAQRVAESNRMERRSVFSERSNAAQYANSDDEEDGYDSPNVKRRGASVDDFLKGSELGKQPHYCHGEDYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRVSLTSHNALKECNKNKTTDATFLEQPDFSQQIHHSKKLFSIPEVAEEDGEYSELLYKQGLGMPYKKKSTIARDSRPPRPYNQDQQHNFWYPAKHRISGMEDFTADDKGCKYSRSLSRSPDSGLDCGSEEEESRFTFRYTCDSVSANVASSCCADTADCSCRKSMRPLLARRKTLTRQTSIEEDFGDLGSSFVEPRSEQVKSSYEKKYETQKCNRTDNLSNEDIQGGWKNDLKMADSRAAGPLAKSSHRDAEDSLLLGNPSSAGRPERVEHAGRRSSHGSAVPQRSRPMLVPSIEITMDSNSEGGRSRSGSEGNISPVKEEAYYRSIGGHKKWPQQRTMASEYRYDGYGGHDHLSPDIYEESETDPGTEDISTRIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCTRIGLIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSRYLHDTPIRTKAKRVPPENTGTSRRAPSPTVHLHSGSPTSPMGSGSPGRGRDMSSKKKKGLLSKGKKLLKKLGAVK", "length": 1503, "header": "tr|A0A8V0ZS47-1|A0A8V0ZLX7_CHICK Computationally mapped isoform of RIMS binding protein 2 OS=Gallus gallus OX=9031 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A8V0ZLX7-1" }, "locus": { "chromosome": "15", "start_pos": 3353138, "end_pos": 3290200, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056622.1", "url": "https://www.ensembl.org/id/ENSGALT00010056622.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034364.1", "url": "https://www.ensembl.org/id/ENSGALP00010034364.1" } ] } }, { "isoform_ac": "A0A8V0ZV88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7/entry#A0A8V0ZV88-1", "sequence": { "sequence": "MKNELKDAVQEKNRLSLQYAIVSHKALQYDQVKSDYDHLRETLIRVTKERDLAVKGKHQLQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIELLQKAQVEAKKEHEGAVQLLEAKVRELEEKCRTQSEQFNLLSRELEKFRQQAGKIDLLSSNPLTSSDISGSPSKSLSQLMNGIATSLGKGHESPSGSRCVISEFIRPLQISGDKPEQLSVKPTFLSKSRSDTPRCRFDSDMDNDQNSNTSKQRYSGKVHLCIARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNETRLSSTLSSEQDQNFINHSGSTLEGDILEISPPSHIDSSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSWLPTNSNYSHVIFLNEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKPPALTATGTSHGANVTGYGVYAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDSSVAAIPSDLLVPPSPHPRTAPKSKPLASAGAPETKEEHLGPHLKIDESWEQTHSASPVHGHTLEPPVPNFHSSLQGRRSPSPNRILPQPQGTPVPNTVAKAMAREAAQRVAESNRMERRSVFSERSNAAQYANSDDEEDGYDSPNVKRRGASVDDFLKGSELGKQPHYCHGEDYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRVSLTSHNALKLLGNPSSAGRPERVEHAGRRSSHGSAVPQRSRPMLVPSIEITMDSNSEGGRSRSGSEGNISPVKEEAYYRSIGGHKKWPQQRTMASEYRYDGYGGHDHLSPDIYEESETDPGTEDISTRIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCTRIGLIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSRYLHDTPIRTKAKRVPPENTGTSRRAPSPTVHLHSGSPTSPMGSGSPGRGRDMSSKKKKGLLSKGKKLLKKLGAVK", "length": 1259, "header": "tr|A0A8V0ZV88-1|A0A8V0ZLX7_CHICK Computationally mapped isoform of RIMS binding protein 2 OS=Gallus gallus OX=9031 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A8V0ZLX7-1" }, "locus": { "chromosome": "15", "start_pos": 3353138, "end_pos": 3290200, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056623.1", "url": "https://www.ensembl.org/id/ENSGALT00010056623.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034365.1", "url": "https://www.ensembl.org/id/ENSGALP00010034365.1" } ] } }, { "isoform_ac": "A0A8V0ZV93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7/entry#A0A8V0ZV93-1", "sequence": { "sequence": "MREAAERRQQLELEHEQALAVLNAKQQEIELLQKAQVEAKKEHEGAVQLLENTLDSMQAKVRELEEKCRTQSEQFNLLSRELEKFRQQAGKIDLLSSNPLTSSDISGSPSKSLSQLMNGIATSLGKGHESPSGSRCVISEFIRPLQISGDKPEQLSVKPTFLSKSRSDTPRCRFDSDMDNDQNSNTSKQRYSGKVHLCIARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNETRLSSTLSSEQDQNFINHSGSTLEGDILEISPPSHIDSSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSWLPTNSNYSHVIFLNEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKPPALTATGTSHGANVTGYGVYAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDSSVAAIPSDLLVPPSPHPRTAPKSKPLASAGAPETKEEHLGPHLKIDESWEQTHSASPVHGHTLEPPVPNFHSSLQGRRSPSPNRILPQPQGTPVPNTVAKAMAREAAQRVAESNRMERRSVFSERSNAAQYANSDDEEDGYDSPNVKRRGASVDDFLKGSELGKQPHYCHGEDYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRVSLTSHNALKLLGNPSSAGRPERVEHAGRRSSHGSAVPQRSRPMLVPSIEITMDSNSEGGRSRSGSEGNISPVKEEAYYRSIGGHKKWPQQRTMASEYRYDGYGGHDHLSPDIYEESETDPGTEDISTRIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCTRIGLIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSRYLHDTPIRTKAKRVPPENTGTSRRAPSPTVHLHSGSPTSPMGSGSPGRGRDMSSKKKKGLLSKGKKLLKKLGAVK", "length": 1193, "header": "tr|A0A8V0ZV93-1|A0A8V0ZLX7_CHICK Computationally mapped isoform of RIMS binding protein 2 OS=Gallus gallus OX=9031 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A8V0ZLX7-1" }, "locus": { "chromosome": "15", "start_pos": 3353138, "end_pos": 3309444, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056628.1", "url": "https://www.ensembl.org/id/ENSGALT00010056628.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034370.1", "url": "https://www.ensembl.org/id/ENSGALP00010034370.1" } ] } }, { "isoform_ac": "A0A8V0ZV99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7/entry#A0A8V0ZV99-1", "sequence": { "sequence": "MHLVNAKAHHLQNINKQSKRIKDVEIQMLQVEREELKNQLGCLREGLMGQKPGNTEELLKQSQKELLWLQRQLSLISTGSSMCVLAANKKNELKDAVQEKNRLSLQYAIVSHKALQYDQVKSDYDHLRETLIRVTKERDLAVKGKHQLQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIELLQKAQVEAKKEHEGAVQLLEAKVRELEEKCRTQSEQFNLLSRELEKFRQQAGKIDLLSSNPLTSSDISGSPSKSLSQLMNGIATSLGKGHESPSGSRCVISEFIRPLQISGDKPEQLSVKPTFLSKSRSDTPRCRFDSDMDNDQNSNTSKQRYSGKVHLCIARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNETRLSSTLSSEQDQNFINHSGSTLEGDILEISPPSHIDSSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSWLPTNSNYSHVIFLNEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKPPALTATGTSHGANVTGYGVYAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDSSVAAIPSDLLVPPSPHPRTAPKSKPLASAGAPETKEEHLGPHLKIDESWEQTHSASPVHGHTLEPPVPNFHSSLQGRRSPSPNRILPQPQGTPVPNTVAKAMAREAAQRVAESNRMERRSVFSERSNAAQYANSDDEEDGYDSPNVKRRGASVDDFLKGSELGKQPHYCHGEDYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRVSLTSHNALKECNKNKTTDATFLEQPDFSQQIHHSKKLFSIPEVAEEDGEYSELLYKQGLGMPYKKKSTIARDSRPPRPYNQDQQHNFWYPAKHRISGMEDFTADDKGCKYSRSLSRSPDSGLDCGSEEEESRFTFRYTCDSVSANVASSCCADTADCSCRKSMRPLLARRKTLTRQTSIEEDFGDLGSSFVEPRSEQVKSSYEKKYETQKCNRTDNLSNEDIQGGWKNDLKMADSRAAGPLAKSSHRDAEDSLLLGNPSSAGRPERVEHAGRRSSHGSAVPQRSRPMLVPSIEITMDSNSEGGRSRSGSEGNISPVKEEAYYRSIGGHKKWPQQRTMASEYRYDGYGGHDHLSPDIYEESETDPGTEDISTRIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCTRIGLIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSRYLHDTPIRTKAKRVPPENTGTSRRAPSPTVHLHSGSPTSPMGSGSPGRGRDMSSKKKKGLLSKGKKLLKKLGAVK", "length": 1591, "header": "tr|A0A8V0ZV99-1|A0A8V0ZLX7_CHICK Computationally mapped isoform of RIMS binding protein 2 OS=Gallus gallus OX=9031 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A8V0ZLX7-1" }, "locus": { "chromosome": "15", "start_pos": 3353138, "end_pos": 3244124, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056633.1", "url": "https://www.ensembl.org/id/ENSGALT00010056633.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034375.1", "url": "https://www.ensembl.org/id/ENSGALP00010034375.1" } ] } }, { "isoform_ac": "A0A8V0ZVA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7/entry#A0A8V0ZVA5-1", "sequence": { "sequence": "MKKAISHILDHDYSVLDSPKANQSFPKAAKSLIKDQEEDKVSKKGNKKAKQTSEKLPHFRPEDGSRQKGSSVTAKKSKDVSPSTSLILPSNNSAVITKTITRTFPFKQKMHLVNAKAHHLQNINKQSKRIKDVEIQMLQVEREELKNQLGCLREGLMGQKPGNTEELLKQSQKELLWLQRQLSLISTGSSMCVLAANKFGNDPSCLQSATSECTSDQVEFIEETWISKSHVTTLNQEYHHWQYSKNELKDAVQEKNRLSLQYAIVSHKALQYDQVKSDYDHLRETLIRVTKERDLAVKGKHQLQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIELLQKAQVEAKKEHEGAVQLLEAKVRELEEKCRTQSEQFNLLSRELEKFRQQAGKIDLLSSNPLTSSDISGSPSKSLSQLMNGIATSLGKGHESPSGSRCVISEFIRPLQISGDKPEQLSVKPTFLSKSRSDTPRCRFDSDMDNDQNSNTSKQRYSGKVHLCIARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNETRLSSTLSSEQDQNFINHSGSTLEGDILEISPPSHIDSSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSWLPTNSNYSHVIFLNEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKPPALTATGTSHGANVTGYGVYAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDSSVAAIPSDLLVPPSPHPRTAPKSKPLASAGAPETKEEHLGPHLKIDESWEQTHSASPVHGHTLEPPVPNFHSSLQGRRSPSPNRILPQPQGTPVPNTVAKAMAREAAQRVAESNRMERRSVFSERSNAAQYANSDDEEDGYDSPNVKRRGASVDDFLKGSELGKQPHYCHGEDYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRVSLTSHNALKLLGNPSSAGRPERVEHAGRRSSHGSAVPQRSRPMLVPSIEITMDSNSEGGRSRSGSEGNISPVKEEAYYRSIGGHKKWPQQRTMASEYRYDGYGGHDHLSPDIYEESETDPGTEDISTRIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCTRIGLIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSRYLHDTPIRTKAKRKKSVHFTP", "length": 1448, "header": "tr|A0A8V0ZVA5-1|A0A8V0ZLX7_CHICK Computationally mapped isoform of RIMS binding protein 2 OS=Gallus gallus OX=9031 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A8V0ZLX7-1" }, "locus": { "chromosome": "15", "start_pos": 3351147, "end_pos": 3232837, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056638.1", "url": "https://www.ensembl.org/id/ENSGALT00010056638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034380.1", "url": "https://www.ensembl.org/id/ENSGALP00010034380.1" } ] } }, { "isoform_ac": "A0A8V0ZZP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7/entry#A0A8V0ZZP8-1", "sequence": { "sequence": "MKKAISHILDHDYSVLDSPKANQSFPKAAKSLIKDQEEDKVSKKGNKKAKQTSEKLPHFRPEDGSRQKGSSVTAKKSKDVSPSTSLILPSNNSAVITKTITRTFPFKQKMHLVNAKAHHLQNINKQSKRIKDVEIQMLQVEREELKNQLGCLREGLMGQKPGNTEELLKQSQKELLWLQRQLSLISTGSSMCVLAANKKNELKDAVQEKNRLSLQYAIVSHKALQYDQVKSDYDHLRETLIRVTKERDLAVKGKHQLQAKLENLEQVLKHMREAAERRQQLELEHEQALAVLNAKQQEIELLQKAQVEAKKEHEGAVQLLEAKVRELEEKCRTQSEQFNLLSRELEKFRQQAGKIDLLSSNPLTSSDISGSPSKSLSQLMNGIATSLGKGHESPSGSRCVISEFIRPLQISGDKPEQLSVKPTFLSKSRSDTPRCRFDSDMDNDQNSNTSKQRYSGKVHLCIARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNETRLSSTLSSEQDQNFINHSGSTLEGDILEISPPSHIDSSVISNGAGTLDVNIDEIGEDIVPYPRKITLIKQLAKSVIVGWEPPVVPPGWGTINSYNVLVDKEVRMNIALGSRTKALIEKLNISTCTYRISIQSITNKGNSDELQCTLLVGKDVVVAPSNLKVDNITQISAELSWLPTNSNYSHVIFLNEEEFDIVKAASYKYHFFNLKPNMAYKVKVMAKPHQMPWQLPLEQREKKEAFVEFSTLPAGPPAPPQDVTVRAGSTQATIQVSWKPPALTATGTSHGANVTGYGVYAKGQRVAEVIFPTAENTLVELMRLRNLEAKEVTVRTLSAQGESVDSSVAAIPSDLLVPPSPHPRTAPKSKPLASAGAPETKEEHLGPHLKIDESWEQTHSASPVHGHTLEPPVPNFHSSLQGRRSPSPNRILPQPQGTPVPNTVAKAMAREAAQRVAESNRMERRSVFSERSNAAQYANSDDEEDGYDSPNVKRRGASVDDFLKGSELGKQPHYCHGEDYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRVSLTSHNALKLLGNPSSAGRPERVEHAGRRSSHGSAVPQRSRPMLVPSIEITMDSNSEGGRSRSGSEGNISPVKEEAYYRSIGGHKKWPQQRTMASEYRYDGYGGHDHLSPDIYEESETDPGTEDISTRIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCTRIGLIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLSDAPSRYLHDTPIRTKAKRKKSVHFTP", "length": 1402, "header": "tr|A0A8V0ZZP8-1|A0A8V0ZLX7_CHICK Computationally mapped isoform of RIMS binding protein 2 OS=Gallus gallus OX=9031 GN=RIMBP2 PE=3 SV=1 CANONICAL=A0A8V0ZLX7-1" }, "locus": { "chromosome": "15", "start_pos": 3351147, "end_pos": 3232837, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056641.1", "url": "https://www.ensembl.org/id/ENSGALT00010056641.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034383.1", "url": "https://www.ensembl.org/id/ENSGALP00010034383.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuromuscular synaptic transmission", "id": "GO:0007274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007274", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1133, "end_pos": 1135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1331, "end_pos": 1333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1335, "end_pos": 1337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1431, "end_pos": 1433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 735, "end_pos": 737, "annotation": "n_glycosylation_sequon" }, { "start_pos": 751, "end_pos": 753, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 823, "end_pos": 924, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZLX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX7" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 502, "end_pos": 569, "start_aa": "Gly", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1133, "end_pos": 1135 }, { "start_pos": 1331, "end_pos": 1333 }, { "start_pos": 1335, "end_pos": 1337 }, { "start_pos": 1431, "end_pos": 1433 }, { "start_pos": 22, "end_pos": 24 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 570, "end_pos": 572 }, { "start_pos": 588, "end_pos": 590 }, { "start_pos": 692, "end_pos": 694 }, { "start_pos": 735, "end_pos": 737 }, { "start_pos": 751, "end_pos": 753 }, { "start_pos": 857, "end_pos": 859 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLC8-1", "uniprot_ac": "A0A8V0ZLC8", "uniprot_id": "A0A8V0ZLC8_CHICK", "mass": { "chemical_mass": 16723.0, "monoisotopic_mass": 16723.0 }, "refseq": {}, "gene_names": [ { "name": "BLOC1S2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ] } ], "protein_names": [ { "name": "Biosis of lysosomal organelles complex 1 subunit 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BLOC1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8", "locus": { "chromosome": "6", "start_pos": 18333655, "end_pos": 18325628, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020632", "url": "https://www.ensembl.org/id/ENSGALG00010020632" } ] } } ], "crossref": [ { "id": "A0A8V0ZLC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005794", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005794", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423768", "url": "https://www.ncbi.nlm.nih.gov/gene/423768", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423768", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423768", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSDMFEK", "url": "https://omabrowser.org/oma/group/CSDMFEK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RL19", "url": "https://www.orthodb.org/?gene=A0A1L1RL19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLC8", "url": "https://www.orthodb.org/?gene=A0A8V0ZLC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46479", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46479", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46479:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46479:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1L1RL19", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RL19-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RL19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAAEGLPEADAQPAKQDPAVETAEEAKEPAEADINELCKDMFSKMATYLTGELTATSEDYKLLENMNKLTSLKYLEMKDIAINISRNLKDLNQKYAALQPYLEQINLIEEQVAALEQAAYKLDAYSKRLDLQDGHKRVMFHQRKLP", "length": 148, "header": "tr|A0A8V0ZLC8-1|A0A8V0ZLC8_CHICK Isoform 1 of Biosis of lysosomal organelles complex 1 subunit 2 OS=Gallus gallus OX=9031 GN=BLOC1S2 PE=1 SV=1 CANONICAL=A0A8V0ZLC8-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RL19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8/entry#A0A1L1RL19-1", "sequence": { "sequence": "MATAAEGLPEADAQPAKQDPAVETAEEAKEPAEADINELCKDMFSKMATYLTGELTATSEDYKLLENMNKLTSLKYLEMKDIAINISRNLKDLNQKYAALQPYLEQINLIEEQVAALEQAAYKLDAYSKRLEAKYKKLEKR", "length": 141, "header": "tr|A0A1L1RL19-1|A0A8V0ZLC8_CHICK Computationally mapped isoform of Biosis of lysosomal organelles complex 1 subunit 2 OS=Gallus gallus OX=9031 GN=BLOC1S2 PE=1 SV=2 CANONICAL=A0A8V0ZLC8-1" }, "locus": { "chromosome": "6", "start_pos": 18329024, "end_pos": 18325700, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049798.1", "url": "https://www.ensembl.org/id/ENSGALT00010049798.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029426.1", "url": "https://www.ensembl.org/id/ENSGALP00010029426.1" } ] } }, { "isoform_ac": "A0A8V0ZLC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8/entry#A0A8V0ZLC8-1", "sequence": { "sequence": "MATAAEGLPEADAQPAKQDPAVETAEEAKEPAEADINELCKDMFSKMATYLTGELTATSEDYKLLENMNKLTSLKYLEMKDIAINISRNLKDLNQKYAALQPYLEQINLIEEQVAALEQAAYKLDAYSKRLDLQDGHKRVMFHQRKLP", "length": 148, "header": "tr|A0A8V0ZLC8-1|A0A8V0ZLC8_CHICK Isoform 1 of Biosis of lysosomal organelles complex 1 subunit 2 OS=Gallus gallus OX=9031 GN=BLOC1S2 PE=1 SV=1 CANONICAL=A0A8V0ZLC8-1" }, "locus": { "chromosome": "6", "start_pos": 18332748, "end_pos": 18325700, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049800.1", "url": "https://www.ensembl.org/id/ENSGALT00010049800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029427.1", "url": "https://www.ensembl.org/id/ENSGALP00010029427.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423768", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423768", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2BIA5-1", "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 2 isoform 1", "gene_name": "bloc1s2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAATGDEAAAMDSISKAPAPPTELNLTAEPENSREATTSDTTENQKPKRPSNNNDGGVETAEEATEPAEPDINELCRDMFDKMSVFLQGELTATCEDYKLLENMNKLTSLKYMEMKDISINISRNLQDLNQKYASLQPYLDQINQIEEQVTALEQAAYKLDTYSKKLEAKFKKLEKR", "length": 177 }, "evidence": [ { "id": "A0A8V0ZLC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLC8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F4K657-1", "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 2", "gene_name": "BLOS2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADSRDDLAESLQNLFTSVSSMVKSELQGTNNHLDLLEKMNLRVASEYDDMGDVAAGLRVFAEQMKSKSGGLDEFVGQMDAIEKQVSEFEAVISVLDRYVSVLESKIRAEYRHPHHQRRSNDSVVTD", "length": 127 }, "evidence": [ { "id": "A0A8V0ZLC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLC8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6QNY1-1", "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 2", "gene_name": "BLOC1S2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAEGVLATRSDEPARDDAAVETAEEAKEPAEADITELCRDMFSKMATYLTGELTATSEDYKLLENMNKLTSLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLEAKYKKLEKR", "length": 142 }, "evidence": [ { "id": "A0A8V0ZLC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CWG9-1", "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 2", "gene_name": "Bloc1s2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAEGVPATRREEQPPRDDAAVETAEEAKEPAEADINELCRDMFSKMATYLTGELTATSEDYKLLENMNKLTSLKYLEMKDIAINISRNLKDLNQKYAELQPYLDQINMIEEQVAALEQAAYKLDAYSKKLEAKYKKLEKR", "length": 143 }, "evidence": [ { "id": "A0A8V0ZLC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLC8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" }, { "name": "BORC complex", "id": "GO:0099078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099078", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" }, { "name": "BLOC-1 complex", "id": "GO:0031083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031083", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" }, { "name": "gamma-tubulin complex", "id": "GO:0000930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" }, { "name": "anterograde synaptic vesicle transport", "id": "GO:0048490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048490", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" }, { "name": "extrinsic apoptotic signaling pathway via death domain receptors", "id": "GO:0008625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" }, { "name": "lysosome localization", "id": "GO:0032418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032418", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" }, { "name": "mitochondrial outer membrane permeabilization", "id": "GO:0097345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097345", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZM84-1", "uniprot_ac": "A0A8V0ZM84", "uniprot_id": "A0A8V0ZM84_CHICK", "mass": { "chemical_mass": 16878.0, "monoisotopic_mass": 16878.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC58", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84" } ] } ], "protein_names": [ { "name": "Protein MIX23", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 58", "type": "synonym", "evidence": [ { "id": "A0A8V0ZM84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84", "locus": { "chromosome": "1", "start_pos": 76736987, "end_pos": 76746394, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021767", "url": "https://www.ensembl.org/id/ENSGALG00010021767" } ] } } ], "crossref": [ { "id": "A0A8V0ZM84", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZM84", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000014413", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000014413", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "418269", "url": "https://www.ncbi.nlm.nih.gov/gene/418269", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RWZ8", "url": "https://www.orthodb.org/?gene=A0A1L1RWZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM84", "url": "https://www.orthodb.org/?gene=A0A8V0ZM84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM95", "url": "https://www.orthodb.org/?gene=A0A8V0ZM95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31905:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31905:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09774", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1L1RWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RWZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPSSTVNCEDFAEFQELLRVMRTIDDRIVHELNTTIPTASFVGKVDASQTCKELYQSLMEAHTSRERIIKNCIAQTSSVVKTLREEREKAQDDVALLKQLRKEQTKPPFRCWKATLKSSLLQAEQCQLRQWNLGSVVLCSYWLDL", "length": 147, "header": "tr|A0A8V0ZM84-1|A0A8V0ZM84_CHICK Isoform 1 of Protein MIX23 OS=Gallus gallus OX=9031 GN=CCDC58 PE=1 SV=1 CANONICAL=A0A8V0ZM84-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RWZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84/entry#A0A1L1RWZ8-1", "sequence": { "sequence": "MAAPSSTVNCEDFAEFQELLRVMRTIDDRIVHELNTTIPTASFVGKVDASQTCKELYQSLMEAHTSRERIIKNCIAQTSSVVKTLREEREKAQDDVALLKQLRKEQTKVFNERCRIHYKPPKSQ", "length": 124, "header": "tr|A0A1L1RWZ8-1|A0A8V0ZM84_CHICK Computationally mapped isoform of Protein MIX23 OS=Gallus gallus OX=9031 GN=CCDC58 PE=1 SV=1 CANONICAL=A0A8V0ZM84-1" }, "locus": { "chromosome": "1", "start_pos": 76746187, "end_pos": 76737237, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052919.1", "url": "https://www.ensembl.org/id/ENSGALT00010052919.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031825.1", "url": "https://www.ensembl.org/id/ENSGALP00010031825.1" } ] } }, { "isoform_ac": "A0A8V0ZM84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84/entry#A0A8V0ZM84-1", "sequence": { "sequence": "MAAPSSTVNCEDFAEFQELLRVMRTIDDRIVHELNTTIPTASFVGKVDASQTCKELYQSLMEAHTSRERIIKNCIAQTSSVVKTLREEREKAQDDVALLKQLRKEQTKPPFRCWKATLKSSLLQAEQCQLRQWNLGSVVLCSYWLDL", "length": 147, "header": "tr|A0A8V0ZM84-1|A0A8V0ZM84_CHICK Isoform 1 of Protein MIX23 OS=Gallus gallus OX=9031 GN=CCDC58 PE=1 SV=1 CANONICAL=A0A8V0ZM84-1" }, "locus": { "chromosome": "1", "start_pos": 76746187, "end_pos": 76744119, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052915.1", "url": "https://www.ensembl.org/id/ENSGALT00010052915.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031821.1", "url": "https://www.ensembl.org/id/ENSGALP00010031821.1" } ] } }, { "isoform_ac": "A0A8V0ZM95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84/entry#A0A8V0ZM95-1", "sequence": { "sequence": "MAAPSSTVNCEDFAEFQELLRVMRTIDDRIVHELNTTIPTASFVGKVDASQTCKELYQSLMEAHTSRERIIKNCIAQTSSVVKTLREEREKAQDDVALLKQLRKEQTKLKLMQSELNVEEVVNDRSWKVLSHFRKRCSSVPWV", "length": 143, "header": "tr|A0A8V0ZM95-1|A0A8V0ZM95_CHICK Computationally mapped isoform of Protein MIX23 OS=Gallus gallus OX=9031 GN=CCDC58 PE=1 SV=1 CANONICAL=A0A8V0ZM84-1" }, "locus": { "chromosome": "1", "start_pos": 76746187, "end_pos": 76740640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052925.1", "url": "https://www.ensembl.org/id/ENSGALT00010052925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031831.1", "url": "https://www.ensembl.org/id/ENSGALP00010031831.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM84", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 35, "end_pos": 37 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJ19-1", "uniprot_ac": "A0A8V0ZJ19", "uniprot_id": "A0A8V0ZJ19_CHICK", "mass": { "chemical_mass": 56506.0, "monoisotopic_mass": 56506.0 }, "refseq": { "ac": "XP_025007473", "name": "prosaposin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007473" }, "gene_names": [ { "name": "LOC423719", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ] }, { "name": "LOC423719", "type": "synonym", "evidence": [ { "id": "XP_025007473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007473" } ] } ], "protein_names": [ { "name": "Prosaposin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19/entry#names_and_taxonomy" } ] }, { "name": "Pulmonary surfactant-associated protein B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19/entry#names_and_taxonomy" } ] }, { "name": "Pulmonary surfactant-associated proteolipid SPL(Phe)", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19/entry#names_and_taxonomy" } ] }, { "name": "prosaposin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025007473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007473" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025007473.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025007473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007473" } ] }, { "annotation": "Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5R8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R8#function" }, { "database": "UniProtKB", "id": "ARBA00037221", "url": "https://www.uniprot.org/uniprotkb/ARBA00037221#function" }, { "database": "UniProtKB", "id": "A0A8V0ZD09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD09#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19#function" } ] }, { "annotation": "Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5R8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R8#function" }, { "database": "UniProtKB", "id": "ARBA00037150", "url": "https://www.uniprot.org/uniprotkb/ARBA00037150#function" }, { "database": "UniProtKB", "id": "A0A8V0ZD09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD09#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19#function" } ] }, { "annotation": "Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5R8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R8#function" }, { "database": "UniProtKB", "id": "ARBA00037606", "url": "https://www.uniprot.org/uniprotkb/ARBA00037606#function" }, { "database": "UniProtKB", "id": "A0A8V0ZD09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD09#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19#function" } ] }, { "annotation": "Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5R8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R8#function" }, { "database": "UniProtKB", "id": "ARBA00037231", "url": "https://www.uniprot.org/uniprotkb/ARBA00037231#function" }, { "database": "UniProtKB", "id": "A0A8V0ZD09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD09#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC423719", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZJ19", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJ19", "database": "AlphaFoldDB", "categories": [] }, { "id": "423719", "url": "https://www.ncbi.nlm.nih.gov/gene/423719", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CKWMVDA", "url": "https://omabrowser.org/oma/group/CKWMVDA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5R8", "url": "https://www.orthodb.org/?gene=A0A8V0Z5R8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD09", "url": "https://www.orthodb.org/?gene=A0A8V0ZD09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ19", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11480", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11480", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11480:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11480:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02199", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02199", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025007473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007473", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5R8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5R8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKWGGWVLILSVCLGYYQAGASPLPECGEQPEDWCRDVGTAAKCGVLELCRLTLWDQAIGQKGIPCHLCQVVVSMMGKILQDNCTEEKLRLFLDKRCQYLPFQDWSVKCKKMVDTGVLILAQLGKQVLSDPKVVCGTIKLCQPRVGREGALKFQEQPSTPADPAQDLAQLSVPFINGVPLLLQPQDLPHSQDSGDLCEDCARLVAAVQLELSNGATTARSLVARAKEECEGLGPVLAQRCNYYLAKYADTATWMLRHLLAEDPRELCGMLELCPTAEPGPLHTLLSEKMAQLLGTLFSNTEATPLCEMCEFAVRTAESLLENNMTEEQLVNDIEKVCYMLPHSVIGQCKDFVDSYGKAVVIMLLEATDPQAVCTMLHICPHWGVAQGAELRAALEPAAGAFCNVCQILISYLDNELLKNETLTELGDVLEKACELLPGPLTSTCEALVVQYEPAAVRLLVQMMDPDFVCTKIRACDSELTSVPCAQGPDYWCISMATATKCDAVEHCRQHVWN", "length": 515, "header": "tr|A0A8V0ZJ19-1|A0A8V0ZJ19_CHICK Isoform 1 of Prosaposin OS=Gallus gallus OX=9031 GN=LOC423719 PE=4 SV=1 CANONICAL=A0A8V0ZJ19-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z5R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19/entry#A0A8V0Z5R8-1", "sequence": { "sequence": "MASKWGGWVLILSVCLGYYQAGASPLPECGEQPEDWCRDVGTAAKCGVLELCRLTLWDQAIGKGIPCHLCQVVVSMMGKILQDNCTEEKLRLFLDKRCQYLPFQDWSVKCKKMVDTGVLILAQLGKQVLSDPKVVCGTIKLCQPRVGREGALKFQEQPSTPADPAQDLAQLSVPFINGVPLLLQPQDLPHSQDSGDLCEDCARLVAAVQLELSNGATTARSLVARAKEECEGLGPVLAQRCNYYLAKYADTATWMLRHLLAEDPRELCGMLELCPTAEPGPLHTLLSEKMAQLLGTLFSNTEATPLCEMCEFAVRTAESLLENNMTEEQLVNDIEKVCYMLPHSVIGQCKDFVDSYGKAVVIMLLEATDPQAILISYLDNELLKNETLTELGDVLEKACELLPGPLTSTCEALVVQYEPAAVRLLVQMMDPDFVCTKIRACDSELTSVPCAQGPDYWCISMATATKCDAVEHCRQHVWN", "length": 479, "header": "tr|A0A8V0Z5R8-1|A0A8V0ZJ19_CHICK Computationally mapped isoform of Prosaposin OS=Gallus gallus OX=9031 GN=LOC423719 PE=4 SV=1 CANONICAL=A0A8V0ZJ19-1" }, "locus": { "chromosome": "6", "start_pos": 12653299, "end_pos": 12647146, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048495.1", "url": "https://www.ensembl.org/id/ENSGALT00010048495.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028596.1", "url": "https://www.ensembl.org/id/ENSGALP00010028596.1" } ] } }, { "isoform_ac": "A0A8V0ZD09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19/entry#A0A8V0ZD09-1", "sequence": { "sequence": "MASKWGGWVLILSVCLGYYQAGASPLPECGEQPEDWCRDVGTAAKCGVLELCRLTLWDQAIGQKGIPCHLCQVVVSMMGKILQDNCTEEKLRLFLDKRCQYLPFQDWSVKCKKMVDTGVLILAQLGKQVLSDPKVVCGTIKLCQPRVGREGALKFQEQPSTPADPAQDLAQLSVPFINGVPLLLQPQDLPHSQDSGDLCEDCARLVAAVQLELSNGATTARSLVARAKEECEGLGPVLAQRCNYYLAKYADTATWMLRHLDPRELCGMLELCPTAEPGPLHTLLSEKMAQLLGTLFSNTEATPLCEMCEFAVRTAESLLENNMTEEQLVNDIEKVCYMLPHSVIGQCKDFVDSYGKAVVIMLLEATDPQAVCTMLHICPHWGVAQGAELRAALEPAAGAFCNVCQILISYLDNELLKNETLTELGDVLEKACELLPGPLTSTCEALVVQYEPAAVRLLVQMMDPDFVCTKIRACDSELTSVPCAQGPDYWCISMATATKCDAVEHCRQHVWN", "length": 512, "header": "tr|A0A8V0ZD09-1|A0A8V0ZJ19_CHICK Computationally mapped isoform of Prosaposin OS=Gallus gallus OX=9031 GN=LOC423719 PE=4 SV=1 CANONICAL=A0A8V0ZJ19-1" }, "locus": { "chromosome": "6", "start_pos": 12653299, "end_pos": 12647146, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048490.1", "url": "https://www.ensembl.org/id/ENSGALT00010048490.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028594.1", "url": "https://www.ensembl.org/id/ENSGALP00010028594.1" } ] } }, { "isoform_ac": "A0A8V0ZJ19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19/entry#A0A8V0ZJ19-1", "sequence": { "sequence": "MASKWGGWVLILSVCLGYYQAGASPLPECGEQPEDWCRDVGTAAKCGVLELCRLTLWDQAIGQKGIPCHLCQVVVSMMGKILQDNCTEEKLRLFLDKRCQYLPFQDWSVKCKKMVDTGVLILAQLGKQVLSDPKVVCGTIKLCQPRVGREGALKFQEQPSTPADPAQDLAQLSVPFINGVPLLLQPQDLPHSQDSGDLCEDCARLVAAVQLELSNGATTARSLVARAKEECEGLGPVLAQRCNYYLAKYADTATWMLRHLLAEDPRELCGMLELCPTAEPGPLHTLLSEKMAQLLGTLFSNTEATPLCEMCEFAVRTAESLLENNMTEEQLVNDIEKVCYMLPHSVIGQCKDFVDSYGKAVVIMLLEATDPQAVCTMLHICPHWGVAQGAELRAALEPAAGAFCNVCQILISYLDNELLKNETLTELGDVLEKACELLPGPLTSTCEALVVQYEPAAVRLLVQMMDPDFVCTKIRACDSELTSVPCAQGPDYWCISMATATKCDAVEHCRQHVWN", "length": 515, "header": "tr|A0A8V0ZJ19-1|A0A8V0ZJ19_CHICK Isoform 1 of Prosaposin OS=Gallus gallus OX=9031 GN=LOC423719 PE=4 SV=1 CANONICAL=A0A8V0ZJ19-1" }, "locus": { "chromosome": "6", "start_pos": 12653299, "end_pos": 12647146, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048488.1", "url": "https://www.ensembl.org/id/ENSGALT00010048488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028592.1", "url": "https://www.ensembl.org/id/ENSGALP00010028592.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7EYI7-1", "protein_name": "Proactivator polypeptide-like 1", "gene_name": "Psapl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLRTLILLSGVLGAAKASPISGPQECARGSEVWCQDLQAAARCQAVRYCQSAVWSKPIVRSLPCSVCQDVAAAAANGMNPDATEADILASVMKTCEWLPHPESSAKCKWMVDNHSPAVLGMLSGTPGTGLAPVCTALTLCEPLQRHLATATSERPLTQEDATEMTSPFLSNGALSFHPSQMPGGAVCQDCIQLISRLQGALESNLTLAEVTVQDQCESLGPGLAALCKNYIRQQFVPTKQTLQILSPQEVCRKGGFCEEWREPAHRLAQVAAVDGVPSLELELPKKNEMQMELGLTCDVCLNVIQEVDKWLMTNSTEALITHALERVCSIMPESLVQQCITLVETYSPSLVQLVSRVTPEKVCETIRLCNSKRQARSIPKAEATTPSLLVDEENYGSFCQGCKRILGVSSQNLDRKSTKRDILNAFKGGCRILPLPYVLQCHRFVAEYEPVLLESLRFMMDPNDLCKKMGACHSPKVPLLGTDQCVIGPSFWCKSPEAAEMCDALEHCQRLVWKKPASEVKDQP", "length": 524 }, "evidence": [ { "id": "A0A8V0ZJ19", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ19/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6NUJ1-1", "protein_name": "Proactivator polypeptide-like 1", "gene_name": "PSAPL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLCALLLLPSLLGATRASPTSGPQECAKGSTVWCQDLQTAARCGAVGYCQGAVWNKPTAKSLPCDVCQDIAAAAGNGLNPDATESDILALVMKTCEWLPSQESSAGCKWMVDAHSSAILSMLRGAPDSAPAQVCTALSLCEPLQRHLATLRPLSKEDTFEAVAPFMANGPLTFHPRQAPEGALCQDCVRQVSRLQEAVRSNLTLADLNIQEQCESLGPGLAVLCKNYLFQFFVPADQALRLLPPQELCRKGGFCEELGAPARLTQVVAMDGVPSLELGLPRKQSEMQMKAGVTCEVCMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQLVAKITPEKVCKFIRLCGNRRRARAVHDAYAIVPSPEWDAENQGSFCNGCKRLLTVSSHNLESKSTKRDILVAFKGGCSILPLPYMIQCKHFVTQYEPVLIESLKDMMDPVAVCKKVGACHGPRTPLLGTDQCALGPSFWCRSQEAAKLCNAVQHCQKHVWKEMHLHAGEHA", "length": 521 }, "evidence": [ { "id": "A0A8V0ZJ19", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ19/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "sphingolipid metabolic process", "id": "GO:0006665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ], "pmid": "" }, { "name": "respiratory gaseous exchange by respiratory system", "id": "GO:0007585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007585", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ], "pmid": "" }, { "name": "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway", "id": "GO:0007193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007193", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ], "pmid": "" }, { "name": "regulation of lipid metabolic process", "id": "GO:0019216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ], "pmid": "" }, { "name": "prostate gland growth", "id": "GO:0060736", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060736", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ], "pmid": "" }, { "name": "epithelial cell differentiation involved in prostate gland development", "id": "GO:0060742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060742", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" }, { "id": "PS51110", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51110" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Saposin A-type", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 62, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZJ19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ19" }, { "id": "PS50015", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50015" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Saposin B-type", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 147, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 325, "end_pos": 327 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46079", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46079:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46079:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11819", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11819", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z672", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z672", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z672-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z672-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBW9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGERRGRAGLLRPPPCSEPRRSQGISHGRGLESTDRSQVFRDGVLLWITLRHSQMTEGRHCQVHLLDDRNLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDIGQSVWLQLDHRVLDHDLPKKPGPATLYFAVRFYIESISFLKDKTTVELFFLNAKSCVHKGQIEVESETVFKLAALVLQEAKGDYSSDENTRKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYTQIKGLTRGQAIVQYMRVVEALPTYGVHYYGVKDKQGIPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLVVQTWYANTSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTEMGTPKVSKLVTLEAKNQLIMASNGSLISSGSQDSEVSEEQKKEKIMELKKKEKLLQEKLLQKVEELKKICLREAELTGKMPKEYPLSAGEEPPQVRRRVGTAFKLDDNLLPTEEDPALQELESNFVIQQKLVEAAKKLASEPDLCKNVKKKRKQEYADAVKKLQEIENSINEYRIKCGKKPTQKSSLTLPDDIIPSESSSLSDTTTYDDGSESLSVPAQRTSSAQLSPRLLPPKSLGLERVHLRKSSMNEQLLESRHSRDALSTHSSPYRTLERAAPSHGGRSMPTTPVLTRNAYSSSHLQPDVSPHHCRQRSGSLESQTHLLSEVPAEKTAFSLTKSQRSSSTEILDDGSSYTSQSSTEYYCVTPTPKPYYTTQTLDNRTRGRRRSKKQHISAAGSGSMPNLAQKDIRNGVYHKSQEQPSSSYYISGYSPYTESDVYYNGGYVYESDTEGQYSVNPSYRSSAHYGYDRYREFRSYNEDEVDRVPHNPYATLRLPRKQVAKTEHITKNIHKALVAEHLRGWYQRASSLKEQGHCLQAGFESDRGSQRSLGFAGLQVPCSPSSRVSSFSSASSANTAGNWRNPLALGLSDYDTLSHSSFASCYGNAYGNLPLQSRVYPEPSQLGGDEENQLEEDLHSNEQRLFWHEDSKPGTLV", "length": 1036, "header": "tr|A0A8V0ZJG9-1|A0A8V0ZJG9_CHICK Isoform 1 of FERM domain containing 4B OS=Gallus gallus OX=9031 GN=FRMD4B PE=4 SV=1 CANONICAL=A0A8V0ZJG9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z672-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9/entry#A0A8V0Z672-1", "sequence": { "sequence": "MFALLKMTEGRHCQVHLLDDRNLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDIGQSVWLQLDHRVLDHDLPKKPGPATLYFAVRFYIESISFLKDKTTVELFFLNAKSCVHKGQIEVESETVFKLAALVLQEAKGDYSSDENTRKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYTQIKGLTRGQAIVQYMRVVEALPTYGVHYYGVKDKQGIPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLVVQTWYANTSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTEMGTPKVSKLVTLEAKNQLIMASNGSLISSGSQDSEVSEEQKKEKIMELKKKEKLLQEKLLQKVEELKKICLREAELTGKMPKEYPLSAGEEPPQVRRRVGTAFKLDDNLLPTEEDPALQELESNFVIQQKLVEAAKKLASEPDLCKNVKKKRKQEYADAVKKLQEIENSINEYRIKCGKKPTQKSSLTLPDDIIPSESSSLSDTTTYDDGSESLSVPAQRTSSAQLSPRLLPPKSLGLERVHLRKSSMNEQLLESRHSRDALSTHSSPYRTLERAAPSHGGRSMPTTPVLTRNAYSSSHLQPDVSPHHCRQRSGSLESQTHLLSEVPAEKTAFSLTKSQRSSSTEILDDGSSYTSQSSTEYYCVTPTPKPYYTTQTLDNRTRGRRRSKKQHISAAGSGSMPNLAQKDIRNGVYHKSQEQPSSSYYISGYSPYTESDVYYNGGYVYESDTEGQYSVNPSYRSSAHYGYDRYREFRSYNEDEVDRVPHNPYATLRLPRKQVAKTEHITKNIHKALVAEHLRGWYQRASSLKEQGHCLQAGFESDRGSQRSLGFAGLQVPCSPSSRVSSFSSASSANTAGNWRNPLALGLSDYDTLSHSSFASCYGNAYGNLPLQSRVYPEPSQLGGDEENQLEEDLHSNEQRLFWHEDSKPGTLV", "length": 987, "header": "tr|A0A8V0Z672-1|A0A8V0ZJG9_CHICK Computationally mapped isoform of FERM domain containing 4B OS=Gallus gallus OX=9031 GN=FRMD4B PE=4 SV=1 CANONICAL=A0A8V0ZJG9-1" }, "locus": { "chromosome": "12", "start_pos": 15635526, "end_pos": 15530511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048656.1", "url": "https://www.ensembl.org/id/ENSGALT00010048656.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028747.1", "url": "https://www.ensembl.org/id/ENSGALP00010028747.1" } ] } }, { "isoform_ac": "A0A8V0ZBW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9/entry#A0A8V0ZBW9-1", "sequence": { "sequence": "MTKLQKDNMRCQEKGVGEEPGGRWKQTACVCVHTLSAHERRRNAPQAGVAGLPPSCAGSRAGRGAVSFSAGTGRLPALTFCSFPAQGQIEVESETVFKLAALVLQEAKGDYSSDENTRKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYTQIKGLTRGQAIVQYMRVVEALPTYGVHYYGVKDKQGIPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLVVQTWYANTSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTEMGTPKVSKLVTLEAKNQLIMASNGSLISSGSQDSEVSEEQKKEKIMELKKKEKLLQEKLLQKVEELKKICLREAELTGKMPKEYPLSAGEEPPQVRRRVGTAFKLDDNLLPTEEDPALQELESNFVIQQKLVEAAKKLASEPDLCKNVKKKRKQEYADAVKKLQEIENSINEYRIKCGKKPTQKSSLTLPGSESLSVPAQRTSSAQLSPRLLPPKSLGLERVHLRKSSMNEQLLESRHSRDALSTHSSPYRTLERAAPSHGGRSMPTTPVLTRNAYSSSHLQPDVSPHHCRQRSGSLESQTHLLSEVPAEKTAFSLTKSQRSSSTEILDDGSSYTSQSSTEYYCVTPTPKPYYTTQTLDNRTRGRRRSKKQHISAAGSGSMPNLAQKDIRNGVYHKSQEQPSSSYYISGYSPYTESDVYYNGGYVYESDTEGQYSVNPSYRSSAHYGYDRYREFRSYNEDEVDRVPHNPYATLRLPRKQVAKTEHITKNIHKALVAEHLRGWYQRASSLKEQGHCLQAGFESDRGSQRSLGFAGLQVPCSPSSRVSSFSSASSANTAGNWRNPLALGLSDYDTLSHSSFASCYGNAYGNLPLQSRVYPEPSQLGGDEENQLEEDLHSNEQRLFWHEDSKPGTLV", "length": 935, "header": "tr|A0A8V0ZBW9-1|A0A8V0ZJG9_CHICK Computationally mapped isoform of FERM domain containing 4B OS=Gallus gallus OX=9031 GN=FRMD4B PE=4 SV=1 CANONICAL=A0A8V0ZJG9-1" }, "locus": { "chromosome": "12", "start_pos": 15567378, "end_pos": 15530511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048618.1", "url": "https://www.ensembl.org/id/ENSGALT00010048618.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028709.1", "url": "https://www.ensembl.org/id/ENSGALP00010028709.1" } ] } }, { "isoform_ac": "A0A8V0ZBZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9/entry#A0A8V0ZBZ1-1", "sequence": { "sequence": "MATEEAWIMSPFFPSSNVQKIQRLSACFLLCASWVSPVLLNQQGCGLEMTEGRHCQVHLLDDRNLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDIGQSVWLQLDHRVLDHDLPKKPGPATLYFAVRFYIESISFLKDKTTVELFFLNAKSCVHKGQIEVESETVFKLAALVLQEAKGDYSSDENTRKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYTQIKGLTRGQAIVQYMRVVEALPTYGVHYYGVKDKQGIPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLVVQTWYANTSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTEMGTPKVSKLVTLEAKNQLIMASNGSLISSGSQDSEVSEEQKKEKIMELKKKEKLLQEKLLQKVEELKKICLREAELTGKMPKEYPLSAGEEPPQVRRRVGTAFKLDDNLLPTEEDPALQELESNFVIQQKLVEAAKKLASEPDLCKNVKKKRKQEYADAVKKLQEIENSINEYRIKCGKKPTQKSSLTLPDDIIPSESSSLSDTTTYDDGSESLSVPAQRTSSAQLSPRLLPPKSLGLERVHLRKSSMNEQLLESRHSRDALSTHSSPYRTLERAAPSHGGRSMPTTPVLTRNAYSSSHLQPDVSPHHCRQRSGSLESQTHLLSEVPAEKTAFSLTKSQRSSSTEILDDGSSYTSQSSTEYYCVTPTPKPYYTTQTLDNRTRGRRRSKKQHISAAGSGSMPNLAQKDIRNGVYHKSQEQPSSSYYISGYSPYTESDVYYNGGYVYESDTEGQYSVNPSYRSSAHYGYDRYREFRSYNEDEVDRVPHNPYATLRLPRKQVAKTEHITKNIHKALVAEHLRGWYQRASSLKEQGHCLQAGFESDRGSQRSLGFAGLQVPCSPSSRVSSFSSASSANTAGNWRNPLALGLSDYDTLSHSSFASCYGNAYGNLPLQSRVYPEPSQLGGDEENQLEEDLHSNEQRLFWHEDSKPGTLV", "length": 1029, "header": "tr|A0A8V0ZBZ1-1|A0A8V0ZJG9_CHICK Computationally mapped isoform of FERM domain containing 4B OS=Gallus gallus OX=9031 GN=FRMD4B PE=4 SV=1 CANONICAL=A0A8V0ZJG9-1" }, "locus": { "chromosome": "12", "start_pos": 15589181, "end_pos": 15530511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048638.1", "url": "https://www.ensembl.org/id/ENSGALT00010048638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028729.1", "url": "https://www.ensembl.org/id/ENSGALP00010028729.1" } ] } }, { "isoform_ac": "A0A8V0ZCX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9/entry#A0A8V0ZCX4-1", "sequence": { "sequence": "MASVLMCGVEDLLLGGSRCVWTLTVTALRRWYAGRLRACRQALRAWCGLGDVYQMTEGRHCQVHLLDDRNLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDIGQSVWLQLDHRVLDHDLPKKPGPATLYFAVRFYIESISFLKDKTTVELFFLNAKSCVHKGQIEVESETVFKLAALVLQEAKGDYSSDENTRKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYTQIKGLTRGQAIVQYMRVVEALPTYGVHYYGVKDKQGIPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLVVQTWYANTSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTEMGTPKVSKLVTLEAKNQLIMASNGSLISSGSQDSEVSEEQKKEKIMELKKKEKLLQEKLLQKVEELKKICLREAELTGKMPKEYPLSAGEEPPQVRRRVGTAFKLDDNLLPTEEDPALQELESNFVIQQKLVEAAKKLASEPDLCKNVKKKRKQEYADAVKKLQEIENSINEYRIKCGKKPTQKSSLTLPDDIIPSESSSLSDTTTYDDGSESLSVPAQRTSSAQLSPRLLPPKSLGLERVHLRKSSMNEQLLESRHSRDALSTHSSPYRTLERAAPSHGGRSMPTTPVLTRNAYSSSHLQPDVSPHHCRQRSGSLESQTHLLSEVPAEKTAFSLTKSQRSSSTEILDDGSSYTSQSSTEYYCVTPTPKPYYTTQTLDNRTRGRRRSKKQHISAAGSGSMPNLAQKDIRNGVYHKSQEQPSSSYYISGYSPYTESDVYYNGGYVYESDTEGQYSVNPSYRSSAHYGYDRYREFRSYNEDEVDRVPHNPYATLRLPRKQVAKTEHITKNIHKALVAEHLRGWYQRASSLKEQGHCLQAGFESDRGSQRSLGFAGLQVPCSPSSRVSSFSSASSANTAGNWRNPLALGLSDYDTLSHSSFASCYGNAYGNLPLQSRVYPEPSQLGGDEENQLEEDLHSNEQRLFWHEDSKPGTLV", "length": 1035, "header": "tr|A0A8V0ZCX4-1|A0A8V0ZJG9_CHICK Computationally mapped isoform of FERM domain containing 4B OS=Gallus gallus OX=9031 GN=FRMD4B PE=4 SV=1 CANONICAL=A0A8V0ZJG9-1" }, "locus": { "chromosome": "12", "start_pos": 15595215, "end_pos": 15530511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048645.1", "url": "https://www.ensembl.org/id/ENSGALT00010048645.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028736.1", "url": "https://www.ensembl.org/id/ENSGALP00010028736.1" } ] } }, { "isoform_ac": "A0A8V0ZDB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9/entry#A0A8V0ZDB5-1", "sequence": { "sequence": "MEVTPQPRGTDSVRIPGLSPCSDENTRKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYTQIKGLTRGQAIVQYMRVVEALPTYGVHYYGVKDKQGIPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLVVQTWYANTSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTEMGTPKVSKLVTLEAKNQLIMASNGSLISSGSQDSEVSEEQKKEKIMELKKKEKLLQEKLLQKVEELKKICLREAELTGKMPKEYPLSAGEEPPQVRRRVGTAFKLDDNLLPTEEDPALQELESNFVIQQKLVEAAKKLASEPDLCKNVKKKRKQEYADAVKKLQEIENSINEYRIKCGKKPTQKSSLTLPDDIIPSESSSLSDTTTYDDGSESLSVPAQRTSSAQLSPRLLPPKSLGLERVHLRKSSMNEQLLESRHSRDALSTHSSPYRTLERAAPSHGGRSMPTTPVLTRNAYSSSHLQPDVSPHHCRQRSGSLESQTHLLSEVPAEKTAFSLTKSQRSSSTEILDDGSSYTSQSSTEYYCVTPTPKPYYTTQTLDNRTRGRRRSKKQHISAAGSGSMPNLAQKDIRNGVYHKSQEQPSSSYYISGYSPYTESDVYYNGGYVYESDTEGQYSVNPSYRSSAHYGYDRYREFRSYNEDEVDRVPHNPYATLRLPRKQVAKTEHITKNIHKALVAEHLRGWYQRASSLKEQGHCLQAGFESDRGSQRSLGFAGLQVPCSPSSRVSSFSSASSANTAGNWRNPLALGLSDYDTLSHSSFASCYGNAYGNLPLQSRVYPEPSQLGGDEENQLEEDLHSNEQRLFWHEDSKPGTLV", "length": 863, "header": "tr|A0A8V0ZDB5-1|A0A8V0ZJG9_CHICK Computationally mapped isoform of FERM domain containing 4B OS=Gallus gallus OX=9031 GN=FRMD4B PE=4 SV=1 CANONICAL=A0A8V0ZJG9-1" }, "locus": { "chromosome": "12", "start_pos": 15563766, "end_pos": 15530511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048614.1", "url": "https://www.ensembl.org/id/ENSGALT00010048614.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028705.1", "url": "https://www.ensembl.org/id/ENSGALP00010028705.1" } ] } }, { "isoform_ac": "A0A8V0ZDG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9/entry#A0A8V0ZDG2-1", "sequence": { "sequence": "MTGTWSCWFRGQSVWLQLDHRVLDHDLPKKPGPATLYFAVRFYIESISFLKDKTTVELFFLNAKSCVHKGQIEVESETVFKLAALVLQEAKGDYSSDENTRKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYTQIKGLTRGQAIVQYMRVVEALPTYGVHYYGVKDKQGIPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLVVQTWYANTSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTEMGTPKVSKLVTLEAKNQLIMASNGSLISSGSQDSEVSEEQKKEKIMELKKKEKLLQEKLLQKVEELKKICLREAELTGKMPKEYPLSAGEEPPQVRRRVGTAFKLDDNLLPTEEDPALQELESNFVIQQKLVEAAKKLASEPDLCKNVKKKRKQEYADAVKKLQEIENSINEYRIKCGKKPTQKSSLTLPDDIIPSESSSLSDTTTYDDGSESLSVPAQRTSSAQLSPRLLPPKSLGLERVHLRKSSMNEQLLESRHSRDALSTHSSPYRTLERAAPSHGGRSMPTTPVLTRNAYSSSHLQPDVSPHHCRQRSGSLESQTHLLSEVPAEKTAFSLTKSQRSSSTEILDDGSSYTSQSSTEYYCVTPTPKPYYTTQTLDNRTRGRRRSKKQHISAAGSGSMPNLAQKDIRNGVYHKSQEQPSSSYYISGYSPYTESDVYYNGGYVYESDTEGQYSVNPSYRSSAHYGYDRYREFRSYNEDEVDRVPHNPYATLRLPRKQVAKTEHITKNIHKALVAEHLRGWYQRASSLKEQGHCLQAGFESDRGSQRSLGFAGLQVPCSPSSRVSSFSSASSANTAGNWRNPLALGLSDYDTLSHSSFASCYGNAYGNLPLQSRVYPEPSQLGGDEENQLEEDLHSNEQRLFWHEDSKPGTLV", "length": 937, "header": "tr|A0A8V0ZDG2-1|A0A8V0ZJG9_CHICK Computationally mapped isoform of FERM domain containing 4B OS=Gallus gallus OX=9031 GN=FRMD4B PE=4 SV=1 CANONICAL=A0A8V0ZJG9-1" }, "locus": { "chromosome": "12", "start_pos": 15581981, "end_pos": 15530511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048654.1", "url": "https://www.ensembl.org/id/ENSGALT00010048654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028745.1", "url": "https://www.ensembl.org/id/ENSGALP00010028745.1" } ] } }, { "isoform_ac": "A0A8V0ZJE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9/entry#A0A8V0ZJE2-1", "sequence": { "sequence": "MTEGRHCQVHLLDDRNLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDIGQSVWLQLDHRVLDHDLPKKPGPATLYFAVRFYIESISFLKDKTTVELFFLNAKSCVHKGQIEVESETVFKLAALVLQEAKGDYSSDENTRKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYTQIKGLTRGQAIVQYMRVVEALPTYGVHYYGVKDKQGIPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLVVQTWYANTSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTEMGTPKVSKLVTLEAKNQLIMASNGSLISSGSQDSEVSEEQKKEKIMELKKKEKLLQEKLLQKVEELKKICLREAELTGKMPKEYPLSAGEEPPQVRRRVGTAFKLDDNLLPTEEDPALQELESNFVIQQKLVEAAKKLASEPDLCKNVKKKRKQEYADAVKKLQEIENSINEYRIKCGKKPTQKSSLTLPDDIIPSESSSLSDTTTYDDGSESLSVPAQRTSSAQLSPRLLPPKSLGLERVHLRKSSMNEQLLESRHSRDALSTHSSPYRTLERAAPSHGGRSMPTTPVLTRNAYSSSHLQPDVSPHHCRQRSGSLESQTHLLSEVPAEKTAFSLTKSQRSSSTEILDDGSSYTSQSSTEYYCVTPTPKPYYTTQTLDNRTRGRRRSKKQHISAAGSGSMPNLAQKDIRNGVYHKSQEQPSSSYYISGYSPYTESDVYYNGGYVYESDTEGQYSVNPSYRSSAHYGYDRYREFRSYNEDEVDRVPHNPYATLRLPRKQVAKTEHITKNIHKALVAEHLRGWYQRASSLKEQGHCLQAGFESDRGSQRSLGFAGLQVPCSPSSRVSSFSSASSANTAGNWRNPLALGLSDYDTLSHSSFASCYGNAYGNLPLQSRAQPPTSARLAAACSLPGCRGFPEDCKEPRIPLGCCRNACRTLAAPALRFRSALVLARQPSPGRTAAACPRSGTDAAMSQCPHAKHSQL", 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gallus OX=9031 GN=FRMD4B PE=4 SV=1 CANONICAL=A0A8V0ZJG9-1" }, "locus": { "chromosome": "12", "start_pos": 15576489, "end_pos": 15530511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048632.1", "url": "https://www.ensembl.org/id/ENSGALT00010048632.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028723.1", "url": "https://www.ensembl.org/id/ENSGALP00010028723.1" } ] } }, { "isoform_ac": "A0A8V0ZJG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9/entry#A0A8V0ZJG9-1", "sequence": { "sequence": 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"length": 1036, "header": "tr|A0A8V0ZJG9-1|A0A8V0ZJG9_CHICK Isoform 1 of FERM domain containing 4B OS=Gallus gallus OX=9031 GN=FRMD4B PE=4 SV=1 CANONICAL=A0A8V0ZJG9-1" }, "locus": { "chromosome": "12", "start_pos": 15629418, "end_pos": 15530511, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048652.1", "url": "https://www.ensembl.org/id/ENSGALT00010048652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028743.1", "url": "https://www.ensembl.org/id/ENSGALP00010028743.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 748, "start_aa": "Thr", "end_pos": 748, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr748", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 750, "start_aa": "Thr", "end_pos": 750, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr750", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG9" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG9", "url": 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"PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 362, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 748, 750 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 340, "end_pos": 342 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 762, "end_pos": 764 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZK19-1", "uniprot_ac": "A0A8V0ZK19", "uniprot_id": "A0A8V0ZK19_CHICK", "mass": { "chemical_mass": 89606.0, "monoisotopic_mass": 89606.0 }, "refseq": { "ac": "XP_015141721", "name": "protein kinase C-binding protein NELL1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141721" }, "gene_names": [ { "name": "NELL1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ] }, { "name": "NELL1", "type": "synonym", "evidence": [ { "id": "XP_015141721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141721" } ] } ], "protein_names": [ { "name": "Protein kinase C-binding protein NELL2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19/entry#names_and_taxonomy" } ] }, { "name": "NEL-like protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZK19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19/entry#names_and_taxonomy" } ] }, { "name": "protein kinase C-binding protein NELL1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141721" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015141721.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141721" } ] }, { "annotation": "May regulate neuronal differentiation, polarization and axon guidance.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z6S7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S7#function" }, { "database": "UniProtKB", "id": "ARBA00055061", "url": "https://www.uniprot.org/uniprotkb/ARBA00055061#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T2#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U4#function" }, { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NELL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19", "locus": { "chromosome": "5", "start_pos": 2706398, "end_pos": 2420385, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020290", "url": "https://www.ensembl.org/id/ENSGALG00010020290" } ] } } ], "crossref": [ { "id": "A0A8V0ZK19", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZK19", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770845", "url": "https://www.ncbi.nlm.nih.gov/gene/770845", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770845", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770845", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ATCECKT", "url": "https://omabrowser.org/oma/group/ATCECKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6S7", "url": "https://www.orthodb.org/?gene=A0A8V0Z6S7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6T2", "url": "https://www.orthodb.org/?gene=A0A8V0Z6T2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z6U4", "url": "https://www.orthodb.org/?gene=A0A8V0Z6U4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE05", "url": "https://www.orthodb.org/?gene=A0A8V0ZE05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK19", "url": "https://www.orthodb.org/?gene=A0A8V0ZK19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK31", "url": "https://www.orthodb.org/?gene=A0A8V0ZK31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK42", "url": "https://www.orthodb.org/?gene=A0A8V0ZK42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24042", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24042", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24042:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24042:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12947", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12947", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015141721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141721", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6S7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6U4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLLLLLWACAAAAGAAVGFGMDPDLQIDIITELDLVNTTIGVTQVPGLHNASKAFLFQDVEREIHAAPHVSEKLVHLFRNKSEFTFLVTLQQKTSTSGVILSIRELEHSYFELESSGLRDEIRYHYRFNGKSRTEVFPYRLADGQWHRIAVSLSASHLLLHVDCNRIYERIIDPPETNLIPESNLWLGQRNRKHGFFKGVIQDVKVVFIPNGYITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAEARLSRLEDCHCEKTCQVNGLIYRDKDSWFEDDHCRNCTCKSGVVECRRMSCPPLDCPPDALPVHVDSQCCKVCKAKCIYGGKVLAEGQRVLAKSCRECQNGVLVKVTETCPPLNCSEKDHVLPENQCCSVCRGHNFCAEGHRCGENSECKNWNTKATCECKNGYLSVQGDSAYCEDIDECTAKMHYCHANTMCVNLPGSYRCDCVRGYVRVDDFSCTEHDECGSGRHNCDENAICTNSVRGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGNHCEKDIDECAEGIIECHNHSRCVNLPGWYHCECRSGFHDNGSYSLSGESCVDIDECALKTHTCWNDSACVNLAGGFDCLCPSGPSCTGDCLHEGGFKRNGQVWTLREDRCSVCSCKDGKIFCRRTACDCENPSADLFCCPECDTRVTSQCLDQTGHKLYRSGDNWTYSCQQCRCLEGEVDCWPLLCPNLNCEYTATSEGECCPHCVSDPCLADNITYDIRKTCLDGYGITRLSGAVWTMVGSPCTTCKCKNGSVCCSVDLECLNNN", "length": 808, "header": "tr|A0A8V0ZK19-1|A0A8V0ZK19_CHICK Isoform 1 of Protein kinase C-binding protein NELL2 OS=Gallus gallus OX=9031 GN=NELL1 PE=4 SV=1 CANONICAL=A0A8V0ZK19-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z6S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19/entry#A0A8V0Z6S7-1", "sequence": { "sequence": "MEPTQRISIWMCFTAVGFGMDPDLQIDIITELDLVNTTIGVTQVPGLHNASKAFLFQDVEREIHAAPHVSEKLVHLFRNKSEFTFLVTLQQKTSTSGVILSIRELEHSYFELESSGLRDEIRYHYRFNGKSRTEVFPYRLADGQWHRIAVSLSASHLLLHVDCNRIYERIIDPPETNLIPESNLWLGQRNRKHGFFKGVIQDVKVVFIPNGYITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAEARLSRLEDCHCEKTCQVNGLIYRDKDSWFEDDHCRNCTCKSGVVECRRMSCPPLDCPPDALPVHVDSQCCKVCKAKCIYGGKVLAEGQRVLAKSCRECQNGVLVKVTETCPPLNCSEKDHVLPENQCCSVCRGHNFCAEGHRCGENSECKNWNTKATCECKNGYLSVQGDSAYCEDIDECTAKMHYCHANTMCVNLPGSYRCDCVRGYVRVDDFSCTEHDECGSGRHNCDENAICTNSVRGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGNHCEKDIDECAEGIIECHNHSRCVNLPGWYHCECRSGFHDNGSYSLSGESCVDIDECALKTHTCWNDSACVNLAGGFDCLCPSGPSCTGDCLHEGGFKRNGQVWTLREDRCSVCSCKDGKIFCRRTACDCENPSADLFCCPECDTRVTSQCLDQTGHKLYRSGDNWTYSCQQCRCLEGEVDCWPLLCPNLNCEYTATSEGECCPHCVSDPCLADNITYDIRKTCLDGYGITRLSGAVWTMVGSPCTTCKCKNGSVCCSVDLECLNNN", "length": 806, "header": "tr|A0A8V0Z6S7-1|A0A8V0ZK19_CHICK Computationally mapped isoform of Protein kinase C-binding protein NELL2 OS=Gallus gallus OX=9031 GN=NELL1 PE=4 SV=1 CANONICAL=A0A8V0ZK19-1" }, "locus": { "chromosome": "5", "start_pos": 2704448, "end_pos": 2423367, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048957.1", "url": "https://www.ensembl.org/id/ENSGALT00010048957.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028938.1", "url": "https://www.ensembl.org/id/ENSGALP00010028938.1" } ] } }, { "isoform_ac": "A0A8V0Z6T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19/entry#A0A8V0Z6T2-1", "sequence": { "sequence": "MEPTQRISIWMCFTAVGFGMDPDLQIDIITELDLVNTTIGVTQVPGLHNASKAFLFQDVEREIHAAPHVSEKLVHLFRNKSEFTFLVTLQQKTSTSGVILSIRELEHSYFELESSGLRDEIRYHYRFNGKSRTEVFPYRLADGQWHRIAVSLSASHLLLHVDCNRIYERIIDPPETNLIPESNLWLGQRNRKHGFFKGVIQDVKVVFIPNGYITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAEARLSRLEDCHCEKTCQVNGLIYRDKDSWFEDDHCRNCTCKSGVVECRRMSCPPLDCPPDALPVHVDSQCCKVCKAKCIYGGKVLAEGQRVLAKSCRECQNGVLVKVTETCPPLNCSEKDHVLPENQCCSVCRGHNFCAEGHRCGENSECKNWNTKATCECKNGYLSVQGDSAYCEDIDECTAKMHYCHANTMCVNLPGSYRCDCVRGYVRVDDFSCTEHDECGSGRHNCDENAICTNSVRGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGNHCEKDIDECAEGIIECHNHSRCVNLPGWYHCECRSGFHDNGSYSLSGESCVDIDECALKTHTCWNDSACVNLAGGFDCLCPSGPSCTGDCLHEGGFKRNGQVWTLREDRCSVCSCKEGEVDCWPLLCPNLNCEYTATSEGECCPHCVSDPCLADNITYDIRKTCLDGYGITRLSGAVWTMVGSPCTTCKCKNGSVCCSVDLECLNNN", "length": 747, "header": "tr|A0A8V0Z6T2-1|A0A8V0ZK19_CHICK Computationally mapped isoform of Protein kinase C-binding protein NELL2 OS=Gallus gallus OX=9031 GN=NELL1 PE=4 SV=1 CANONICAL=A0A8V0ZK19-1" }, "locus": { "chromosome": "5", "start_pos": 2704448, "end_pos": 2423367, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048965.1", "url": "https://www.ensembl.org/id/ENSGALT00010048965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028943.1", "url": "https://www.ensembl.org/id/ENSGALP00010028943.1" } ] } }, { "isoform_ac": "A0A8V0Z6U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19/entry#A0A8V0Z6U4-1", "sequence": { "sequence": "MGLLLLLWACAAAAGAAVGFGMDPDLQIDIITELDLVNTTIGVTQVPGLHNASKAFLFQDVEREIHAAPHVSEKLVHLFRNKSEFTFLVTLQQKTSTSGVILSIRELEHSYFELESSGLRDEIRYHYRFNGKSRTEVFPYRLADGQWHRIAVSLSASHLLLHVDCNRIYERIIDPPETNLIPESNLWLGQRNRKHGFFKGVIQDVKVVFIPNGYITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAEARLSRLEDCHCEKTCQVNGLIYRDKDSWFEDDHCRNCTCKSGVVECRRMSCPPLDCPPDALPVHVDSQCCKVCKAKCIYGGKVLAEGQRVLAKSCRECQNGVLVKVTETCPPLNCSEKDHVLPENQCCSVCRGHNFCAEGHRCGENSECKNWNTKATCECKNGYLSVQGDSAYCEEHDECGSGRHNCDENAICTNSVRGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGNHCEKDIDECAEGIIECHNHSRCVNLPGWYHCECRSGFHDNGSYSLSGESCVDIDECALKTHTCWNDSACVNLAGGFDCLCPSGPSCTGDCLHEGGFKRNGQVWTLREDRCSVCSCKDGKIFCRRTACDCENPSADLFCCPECDTRVTSQCLDQTGHKLYRSGDNWTYSCQQCRCLEGEVDCWPLLCPNLNCEYTATSEGECCPHCVSDPCLADNITYDIRKTCLDGYGITRLSGAVWTMVGSPCTTCKCKNGSVCCSVDLECLNNN", "length": 766, "header": "tr|A0A8V0Z6U4-1|A0A8V0ZK19_CHICK Computationally mapped isoform of Protein kinase C-binding protein NELL2 OS=Gallus gallus OX=9031 GN=NELL1 PE=4 SV=1 CANONICAL=A0A8V0ZK19-1" }, "locus": { "chromosome": "5", "start_pos": 2704448, "end_pos": 2420510, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048979.1", "url": "https://www.ensembl.org/id/ENSGALT00010048979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028953.1", "url": "https://www.ensembl.org/id/ENSGALP00010028953.1" } ] } }, { "isoform_ac": "A0A8V0ZE05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19/entry#A0A8V0ZE05-1", "sequence": { "sequence": "MGLLLLLWACAAAAGAAVGFGMDPDLQIDIITELDLVNTTIGVTQVPGLHNASKAFLFQDVEREIHAAPHVSEKLVHLFRNKSEFTFLVTLQQKTSTSGVILSIRELEHSYFELESSGLRDEIRYHYRFNGKSRTEVFPYRLADGQWHRIAVSLSASHLLLHVDCNRIYERIIDPPETNLIPESNLWLGQRNRKHGFFKGVIQDVKVVFIPNGYITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAEARLSRLEDCHCEKTCQVNGLIYRDKDSWFEDDHCRNCTCKSGVVECRRMSCPPLDCPPDALPVHVDSQCCKVCKAKCIYGGKVLAEGQRVLAKSCRECQNGVLVKVTETCPPLNCSEKDHVLPENQCCSVCRGHNFCAEGHRCGENSECKNWNTKATCECKNGYLSVQGDSAYCEDIDECTAKMHYCHANTMCVNLPGSYRCDCVRGYVRVDDFSCTEHDECGSGRHNCDENAICTNSVRGHSCTCKPGYVGNGTICRDIDECALKTHTCWNDSACVNLAGGFDCLCPSGPSCTGDCLHEGGFKRNGQVWTLREDRCSVCSCKDGKIFCRRTACDCENPSADLFCCPECDTRVTSQCLDQTGHKLYRSGDNWTYSCQQCRCLEGEVDCWPLLCPNLNCEYTATSEGECCPHCVSDPCLADNITYDIRKTCLDGYGITRLSGAVWTMVGSPCTTCKCKNGSVCCSVDLECLNNN", "length": 729, "header": "tr|A0A8V0ZE05-1|A0A8V0ZK19_CHICK Computationally mapped isoform of Protein kinase C-binding protein NELL2 OS=Gallus gallus OX=9031 GN=NELL1 PE=4 SV=1 CANONICAL=A0A8V0ZK19-1" }, "locus": { "chromosome": "5", "start_pos": 2704448, "end_pos": 2420510, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048970.1", "url": "https://www.ensembl.org/id/ENSGALT00010048970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028946.1", "url": "https://www.ensembl.org/id/ENSGALP00010028946.1" } ] } }, { "isoform_ac": "A0A8V0ZK19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19/entry#A0A8V0ZK19-1", "sequence": { "sequence": "MGLLLLLWACAAAAGAAVGFGMDPDLQIDIITELDLVNTTIGVTQVPGLHNASKAFLFQDVEREIHAAPHVSEKLVHLFRNKSEFTFLVTLQQKTSTSGVILSIRELEHSYFELESSGLRDEIRYHYRFNGKSRTEVFPYRLADGQWHRIAVSLSASHLLLHVDCNRIYERIIDPPETNLIPESNLWLGQRNRKHGFFKGVIQDVKVVFIPNGYITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAEARLSRLEDCHCEKTCQVNGLIYRDKDSWFEDDHCRNCTCKSGVVECRRMSCPPLDCPPDALPVHVDSQCCKVCKAKCIYGGKVLAEGQRVLAKSCRECQNGVLVKVTETCPPLNCSEKDHVLPENQCCSVCRGHNFCAEGHRCGENSECKNWNTKATCECKNGYLSVQGDSAYCEDIDECTAKMHYCHANTMCVNLPGSYRCDCVRGYVRVDDFSCTEHDECGSGRHNCDENAICTNSVRGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGNHCEKDIDECAEGIIECHNHSRCVNLPGWYHCECRSGFHDNGSYSLSGESCVDIDECALKTHTCWNDSACVNLAGGFDCLCPSGPSCTGDCLHEGGFKRNGQVWTLREDRCSVCSCKDGKIFCRRTACDCENPSADLFCCPECDTRVTSQCLDQTGHKLYRSGDNWTYSCQQCRCLEGEVDCWPLLCPNLNCEYTATSEGECCPHCVSDPCLADNITYDIRKTCLDGYGITRLSGAVWTMVGSPCTTCKCKNGSVCCSVDLECLNNN", "length": 808, "header": "tr|A0A8V0ZK19-1|A0A8V0ZK19_CHICK Isoform 1 of Protein kinase C-binding protein NELL2 OS=Gallus gallus OX=9031 GN=NELL1 PE=4 SV=1 CANONICAL=A0A8V0ZK19-1" }, "locus": { "chromosome": "5", "start_pos": 2704448, "end_pos": 2420510, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048974.1", "url": "https://www.ensembl.org/id/ENSGALT00010048974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028949.1", "url": "https://www.ensembl.org/id/ENSGALP00010028949.1" } ] } }, { "isoform_ac": "A0A8V0ZK31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19/entry#A0A8V0ZK31-1", "sequence": { "sequence": "MGLLLLLWACAAAAGAAVGFGMDPDLQIDIITELDLVNTTIGVTQVPGLHNASKAFLFQDVEREIHAAPHVSEKLVHLFRNKSEFTFLVTLQQKTSTSGVILSIRELEHSYFELESSGLRDEIRYHYRFNGKSRTEVFPYRLADGQWHRIAVSLSASHLLLHVDCNRIYERIIDPPETNLIPESNLWLGQRNRKHGFFKGVIQDVKVVFIPNGYITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAEARLSRLEDCHCEKTCQVNGLIYRDKDSWFEDDHCRNCTCKSGVVECRRMSCPPLDCPPDALPVHVDSQCCKVCKAKCIYGGKVLAEGQRVLAKSCRECQNGVLVKVTETCPPLNCSEKDHVLPENQCCSVCRGHNFCAEGHRCGENSECKNWNTKATCECKNGYLSVQGDSAYCEDIDECTAKMHYCHANTMCVNLPGSYRCDCVRGYVRVDDFSCTEHDECGSGRHNCDENAICTNSVRGHSCTCKPGYVGNGTICRGWYHCECRSGFHDNGSYSLSGESCVDIDECALKTHTCWNDSACVNLAGGFDCLCPSGPSCTGDCLHEGGFKRNGQVWTLREDRCSVCSCKDGKIFCRRTACDCENPSADLFCCPECDTRVTSQCLDQTGHKLYRSGDNWTYSCQQCRCLEGEVDCWPLLCPNLNCEYTATSEGECCPHCVSDPCLADNITYDIRKTCLDGYGITRLSGAVWTMVGSPCTTCKCKNGSVCCSVDLECLNNN", "length": 754, "header": "tr|A0A8V0ZK31-1|A0A8V0ZK31_CHICK Computationally mapped isoform of Neural EGFL like 1 OS=Gallus gallus OX=9031 GN=NELL1 PE=4 SV=1 CANONICAL=A0A8V0ZK19-1" }, "locus": { "chromosome": "5", "start_pos": 2704448, "end_pos": 2420510, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048988.1", "url": "https://www.ensembl.org/id/ENSGALT00010048988.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028959.1", "url": "https://www.ensembl.org/id/ENSGALP00010028959.1" } ] } }, { "isoform_ac": "A0A8V0ZK42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19/entry#A0A8V0ZK42-1", "sequence": { "sequence": "MEPTQRISIWMCFTAVGFGMDPDLQIDIITELDLVNTTIGVTQVPGLHNASKAFLFQDVEREIHAAPHVSEKLVHLFRNKSEFTFLVTLQQKTSTSGVILSIRELEHSYFELESSGLRDEIRYHYRFNGKSRTEVFPYRLADGQWHRIAVSLSASHLLLHVDCNRIYERIIDPPETNLIPESNLWLGQRNRKHGFFKGVIQDVKVVFIPNGYITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAEARLSRLEDCHCEKTCQVNGLIYRDKDSWFEDDHCRNCTCKSGVVECRRMSCPPLDCPPDALPVHVDSQCCKVCKAKCIYGGKVLAEGQRVLAKSCRECQNGVLVKVTETCPPLNCSEKDHVLPENQCCSVCRGHNFCAEGHRCGENSECKNWNTKATCECKNGYLSVQGDSAYCEDIDECTAKMHYCHANTMCVNLPGSYRCDCVRGYVRVDDFSCTEHDECGSGRHNCDENAICTNSVRGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGNHCEKDIDECALKTHTCWNDSACVNLAGGFDCLCPSGPSCTGDCLHEGGFKRNGQVWTLREDRCSVCSCKDGKIFCRRTACDCENPSADLFCCPECDTRVTSQCLDQTGHKLYRSGDNWTYSCQQCRCLEGEVDCWPLLCPNLNCEYTATSEGECCPHCVSDPCLADNITYDIRKTCLDGYGITRLSGAVWTMVGSPCTTCKCKNGSVCCSVDLECLNNN", "length": 759, "header": "tr|A0A8V0ZK42-1|A0A8V0ZK42_CHICK Computationally mapped isoform of Neural EGFL like 1 OS=Gallus gallus OX=9031 GN=NELL1 PE=4 SV=1 CANONICAL=A0A8V0ZK19-1" }, "locus": { "chromosome": "5", "start_pos": 2704448, "end_pos": 2423367, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048993.1", "url": "https://www.ensembl.org/id/ENSGALT00010048993.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028964.1", "url": "https://www.ensembl.org/id/ENSGALP00010028964.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770845", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770845", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q2VWQ2-1", "protein_name": "Protein kinase C-binding protein NELL1", "gene_name": "Nell1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"uniprot_canonical_ac": "Q62919-1", "protein_name": "Protein kinase C-binding protein NELL1", "gene_name": "Nell1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPMDVILVLWFCVCTARTVLGFGMDPDLQLDIISELDLVNTTLGVTQVAGLHNASKAFLFQDVQREIHSAPHVSEKLIQLFRNKSEFTFLATVQQKPSTSGVILSIRELEHSYFELESSGPREEIRYHYIHGGKPRTEALPYRMADGQWHKVALSVSASHLLLHIDCNRIYERVIDPPETNLPPGSNLWLGQRNQKHGFFKGIIQDGKIIFMPNGFITQCPNLNRTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAETRLGQLENCHCEKTCQVSGLLYRDQDSWVDGDNCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHISGQCCKVCRPKCIYGGKVLAEGQRILTKTCRECRGGVLVKITEACPPLNCSAKDHILPENQCCRVCPGHNFCAEAPKCGENSECKNWNTKATCECKNGYISVQGNSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDDCGSGQHNCDKNAICTNTVQGHSCTCQPGYVGNGTICKAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECAEGFVECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWILREDRCSVCSCKDGKIFCRRTACDCQNPNVDLFCCPECDTRVTSQCLDQSGQKLYRSGDNWTHSCQQCRCLEGEADCWPLACPSLGCEYTAMFEGECCPRCVSDPCLADNIAYDIRKTCLDSFGVSRLSGAVWTMAGSPCTTCKCKNGRVCCSVDLECIENN", "length": 810 }, "evidence": [ { "id": "A0A8V0ZK19", "url": "https://omabrowser.org/oma/group/A0A8V0ZK19/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q92832-1", "protein_name": "Protein kinase C-binding protein NELL1", "gene_name": "NELL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPMDLILVVWFCVCTARTVVGFGMDPDLQMDIVTELDLVNTTLGVAQVSGMHNASKAFLFQDIEREIHAAPHVSEKLIQLFRNKSEFTILATVQQKPSTSGVILSIRELEHSYFELESSGLRDEIRYHYIHNGKPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRIYERVIDPPDTNLPPGINLWLGQRNQKHGLFKGIIQDGKIIFMPNGYITQCPNLNHTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSPCTTCKCKNGRVCCSVDFECLQNN", "length": 810 }, "evidence": [ { "id": "A0A8V0ZK19", "url": "https://omabrowser.org/oma/group/A0A8V0ZK19/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ], "pmid": "" }, { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ], "pmid": "" }, { "name": "protein kinase C binding", "id": "GO:0005080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of bone mineralization", "id": "GO:0030501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030501", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ], "pmid": "" }, { "name": "positive regulation of osteoblast differentiation", "id": "GO:0045669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ], "pmid": "" }, { "name": "negative regulation of protein catabolic process", "id": "GO:0042177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK19" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKH6-1", "uniprot_ac": "A0A8V0ZKH6", "uniprot_id": "A0A8V0ZKH6_CHICK", "mass": { "chemical_mass": 160581.0, "monoisotopic_mass": 160581.0 }, "refseq": {}, "gene_names": [ { "name": "LRPPRC", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ] } ], "protein_names": [ { "name": "Leucine rich pentatricopeptide repeat containing", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRPPRC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6", "locus": { "chromosome": "3", "start_pos": 24947979, "end_pos": 25034074, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020375", "url": "https://www.ensembl.org/id/ENSGALG00010020375" } ] } } ], "crossref": [ { "id": "421403", "url": "https://www.ncbi.nlm.nih.gov/gene/421403", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421403", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421403", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIDRNKI", "url": "https://omabrowser.org/oma/group/HIDRNKI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z784", "url": "https://www.orthodb.org/?gene=A0A8V0Z784", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE27", "url": "https://www.orthodb.org/?gene=A0A8V0ZE27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKH1", "url": "https://www.orthodb.org/?gene=A0A8V0ZKH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKH6", "url": "https://www.orthodb.org/?gene=A0A8V0ZKH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46669", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46669", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46669:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46669:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13812", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13812", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23276", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23276", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z784", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z784", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z784-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z784-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCCGPAARGRKRGRETAPQLFSVPRGMARGTSALCGRVPRGQRVKSQVYLQAVIFASVRNGLPQSCGGPSLGALKARNVIHQARFLTVVPQREGSVKEEPVSEIQNRRSWQFDWALNKLDHSVRKTGRIPKTLLLKVFQETCREGCPGSNQTLLLLRSCGALLPEVLSSERTELAHMIWDKMKELGAVYDTSHYNALLKVYLQNEHKFSPTEFLARMEEANVQPNRVTYQRLIAAYCNEGDIEGASKILGFMKSKDLPITEAVFSSLVKGHARSGDIKSAENILSVMRMAGVEPGPDTYLSLLNVYAEKGDADSIKKTLEEVEKTEGYLMDRVLMQVIFSLAKAGYPQYIEDIKERMRFEKELIPDMMNLCLTLITHGFEDISFRILKSYNHLSRENVDQGSFFLQHCVNRNMPMSKLKQFCNELKEAKMHSAPLIFILRCALETNKSGLAIDVMRAMKEEGLPLRPHYCWPLLVGFQKEKNLKGVFEVLKVMHELGVELNAETYTDYVFKNFADIETACAQMKENNCLFETDGLFVAQIRHEAGHGRLKNVVSLLSSASTPSIDFRQFRNSLILGFRSSNDVQLWSQITELLYKDERYCLTPPGPTEAVGYFLYHLIDSMSDSEVQAKEERLRQYFHQLKKMNVVIPATYCSGICRLLDSSQVPELIKDVRSLSPKKFMSTEDIPDSAKSDVSALEKKLEKRKAENQPITDVLKQLIYALCEEENMQKALEVKAKYEPDMVVGGYAALINLCCRHDNVEEAMNLKEKVFPKSSPVALDSGKYIALVEVLAKRGRLEDAINVLREMKEKDVPISERAVASFFRLLNAAAIRGEVETVNRLHETIVNLGLAETAALYSPLITVHLEKDDMPAVLEALMDCYKKHGKILQLHNIYCRLIEKGDTELLRKVSDFISSEYGDMMALYDLFFAFLQTGKYKEARKVIETPGLRAHSGRLQWFAKRCISGNQMETLEHLVELTQNVFECDRDEMYYYLLQLCDNNSDWRRAEAVWTKIQEENVVPREKTLRLLADIFEKNGQVVPFEVPKTRQEEMRSPGSSDIEERKIRMLCKKNSAREAYNVFLKNQGKSDYQYRTYDTLIKALLSLDCIEEAMKVKHTAETHIKGFTLNSAASSLLIISQVRRDYLKDAVAAFQGMLDSGLLPSRPAVIALTQALAMKGDLRNLKALENMVESITQSIGLSPSLISNAIALAHTNNNDLDAAVEYLEPLLISGAQNPDQPVKNISFLLRKVSEKGLEPALEKFGVMAERLANQFGIYRPVTDLFLQYVSADRVDDARSLLQRCGGLVEEKRAFVNYMTKAASKPGQARKIEKLLELIPDSIDLETAYRHLIRCYELDGDVASVKAVYEKTKEKNIQLPELSLKSLAAFLKKAGEPVPFTEPPESFKFYVEEWRKRRLEAS", "length": 1418, "header": "tr|A0A8V0ZKH6-1|A0A8V0ZKH6_CHICK Isoform 1 of Leucine rich pentatricopeptide repeat containing OS=Gallus gallus OX=9031 GN=LRPPRC PE=1 SV=1 CANONICAL=A0A8V0ZKH6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z784-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6/entry#A0A8V0Z784-1", "sequence": { "sequence": "MAALLSSAGRLRSLCVRLRPLLLPPAPAAARNVIHQARFLTVVPQREGSVKEEPVSEIQNRRSWQFDWALNKLDHSVRKTGRIPKTLLLKVFQETCREGCPGSNQTLLLLRSCGALLPEVLSSERTELAHMIWDKMKELGAVYDTSHYNALLKVYLQNEHKFSPTEFLARMEEANVQPNRVTYQRLIAAYCNEGDIEGASKILGFMKSKDLPITEAVFSSLVKGHARSGDIKSAENILSVMRMAGVEPGPDTYLSLLNVYAEKGDADSIKKTLEEVEKTEGYLMDRVLMQVIFSLAKAGYPQYIEDIKERMRFEKELIPDMMNLCLTLITHGFEDISFRILKSYNHLSRENVDQGSFFLQHCVNRNMPMSKLKQFCNELKEAKMHSAPLIFILRCALETNKSGLAIDVMRAMKEEGLPLRPHYCWPLLVGFQKEKNLKGVFEVLKVMHELGVELNAETYTDYVFKNFADIETACAQMKENNCLFETDGLFVAQIRHEAGHGRLKNVVSLLSSASTPSIDFRQFRNSLILGFRSSNDVQLWSQITELLYKDERYCLTPPGPTEAVGYFLYHLIDSMSDSEVQAKEERLRQYFHQLKKMNVVIPATYCSGICRLLDSSQVPELIKDVRSLSPKKFMSTEDIPDSAKSDVSALEKKLEKRKAENQPITDVLKQLIYALCEEENMQKALEVKAKYEPDMVVGGYAALINLCCRHDNVEEAMNLKEKVFPKSSPVALDSGKYIALVEVLAKRGRLEDAINVLREMKEKDVPISERAVASFFRLLNAAAIRGEVETVNRLHETIVNLGLAETAALYSPLITVHLEKDDMPAVLEALMDCYKKHGKILQLHNIYCRLIEKGDTELLRKVSDFISSEYGDMMALYDLFFAFLQTGKYKEARKVIETPGLRAHSGRLQWFAKRCISGNQMETLEHLVELTQNVFECDRDEMYYYLLQLCDNNSDWRRAEAVWTKIQEENVVPREKTLRLLADIFEKNGQVVPFEVPKTRQEEMRSPGSSDIEERKIRMLCKKNSAREAYNVFLKNQGKSDYQYRTYDTLIKALLSLDCIEEAMKVKHTAETHIKGFTLNSAASSLLIISQVRRDYLKDAVAAFQGMLDSGLLPSRPAVIALTQALAMKGDLRNLKALENMVESITQSIGLSPSLISNAIALAHTNNNDLDAAVEYLEPLLISGAQNPDQPVKNISFLLRKVSEKGLEPALEKFGVMAERLANQFGIYRPVTDLFLQYVSADRVDDARSLLQRCGGLVEEKRAFVNYMTKAASKPGQARKIEKLLELIPDSIDLETAYRHLIRCYELDGDVASVKAVYEKTKEKNIQLPELSLKSLAAFLKKAGEPVPFTEPPESFKFYVEEWRKRRLEAS", "length": 1371, "header": "tr|A0A8V0Z784-1|A0A8V0ZKH6_CHICK Computationally mapped isoform of Leucine rich pentatricopeptide repeat containing OS=Gallus gallus OX=9031 GN=LRPPRC PE=1 SV=1 CANONICAL=A0A8V0ZKH6-1" }, "locus": { "chromosome": "3", "start_pos": 25033990, "end_pos": 24948580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049236.1", "url": "https://www.ensembl.org/id/ENSGALT00010049236.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029107.1", "url": "https://www.ensembl.org/id/ENSGALP00010029107.1" } ] } }, { "isoform_ac": "A0A8V0ZE27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6/entry#A0A8V0ZE27-1", "sequence": { "sequence": "MAALLSSAGRLRSLCVRLRPLLLPPAPAAARNVIHQARFLTVVPQREGSVKEEPVSEIQNRRSWQFDWALNKLDHSVRKTGRIPKTLLLKVFQETCREGCPGSNQTLLLLRSCGALLPEVLSSERTELAHMIWDKMKELGAVYDTSHYNALLKVYLQNEHKFSPTEFLARMEEANVQPNRVTYQRLIAAYCNEGDIEGASKILGFMKSKDLPITEAVFSSLVKGHARSGDIKSAENILSVMRMAGVEPGPDTYLSLLNVYAEKGDADSIKKTLEEVEKTEGYLMDRVLMQVIFSLAKAGYPQYIEDIKERMRFEKELIPDMMNLCLTLITHGFEDISFRILKSYNHLSRENVDQGSFFLQHCVNRNMPMSKLKQFCNELKEAKMHSAPLIFILRCALETNKSGLAIDVMRAMKEEGLPLRPHYCWPLLVGFQKEKNLKGVFEVLKVMHELGVELNAETYTDYVFKNFADIETACAQMKENNCLFETDGLFVAQIRHEAGHGRLKNVVSLLSSASTPSIDFRQFRNSLILGFRSSNDVQLWSQITELLYKDERYCLTPPGPTAVGYFLYHLIDSMSDSEVQAKEERLRQYFHQLKKMDVRSLSPKKFMSTEDIPDSAKSDVSALEKKLEKRKAENQPITDVLKQLIYALCEEENMQKALEVKAKYEPDMVVGGYAALINLCCRHDNVEEAMNLKEKVFPKSSPVALDSGKYIALVEVLAKRGRLEDAINVLREMKEKDVPISERAVASFFRLLNAAAIRGEVETVNRLHETIVNLGLAETAALYSPLITVHLEKDDMPAVLEALMDCYKKHGKILQLHNIYCRLIEKGDTELLRKVSDFISSEYGDMMALYDLFFAFLQTGKYKEARKVIETPGLRAHSGRLQWFAKRCISGNQMETLEHLVELTQNVFECDRDEMYYYLLQLCDNNSDWRRAEAVWTKIQEENVVPREKTLRLLADIFEKNGQVVPFEVPKTRQEEMRSPGSSDIEERKIRMLCKKNSAREAYNVFLKNQGKSDYQYRTYDTLIKALLSLDCIEEAMKVKHTAETHIKGFTLNSAASSLLIISQVRRDYLKDAVAAFQGMLDSGLLPSRPAVIALTQALAMKGDLRNLKALENMVESITQSIGLSPSLISNAIALAHTNNNDLDAAVEYLEPLLISGAQNPDQPVKNISFLLRKVSEKGLEPALEKFGVMAERLANQFGIYRPVTDLFLQYVSADRVDDARSLLQRCGGLVEEKRAFVNYMTKAASKPGQARKIEKLLELIPDSIDLETAYRHLIRCYELDGDVASVKAVYEKTKEKNIQLPELSLKSLAAFLKKAGEPVPFTEPPESFKFYVEEWRKRRLEAS", "length": 1344, "header": "tr|A0A8V0ZE27-1|A0A8V0ZKH6_CHICK Computationally mapped isoform of Leucine rich pentatricopeptide repeat containing OS=Gallus gallus OX=9031 GN=LRPPRC PE=1 SV=1 CANONICAL=A0A8V0ZKH6-1" }, "locus": { "chromosome": "3", "start_pos": 25033990, "end_pos": 24948580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049233.1", "url": "https://www.ensembl.org/id/ENSGALT00010049233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029105.1", "url": "https://www.ensembl.org/id/ENSGALP00010029105.1" } ] } }, { "isoform_ac": "A0A8V0ZKH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6/entry#A0A8V0ZKH1-1", "sequence": { "sequence": "MAALLSSAGRLRSLCVRLRPLLLPPAPAAARNVIHQARFLTVVPQREGSVKEEPVSEIQNRRSWQFDWALNKLDHSVRKTGRIPKTLLLKVFQETCREELAHMIWDKMKELGAVYDTSHYNALLKVYLQNEHKFSPTEFLARMEEANVQPNRVTYQRLIAAYCNEGDIEGASKILGFMKSKDLPITEAVFSSLVKGHARSGDIKSRKYPFRDEDGWC", "length": 217, "header": "tr|A0A8V0ZKH1-1|A0A8V0ZKH1_CHICK Computationally mapped isoform of Leucine rich pentatricopeptide repeat containing OS=Gallus gallus OX=9031 GN=LRPPRC PE=1 SV=1 CANONICAL=A0A8V0ZKH6-1" }, "locus": { "chromosome": "3", "start_pos": 25033990, "end_pos": 25019146, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049226.1", "url": "https://www.ensembl.org/id/ENSGALT00010049226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029102.1", "url": "https://www.ensembl.org/id/ENSGALP00010029102.1" } ] } }, { "isoform_ac": "A0A8V0ZKH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6/entry#A0A8V0ZKH6-1", "sequence": { "sequence": "MLCCGPAARGRKRGRETAPQLFSVPRGMARGTSALCGRVPRGQRVKSQVYLQAVIFASVRNGLPQSCGGPSLGALKARNVIHQARFLTVVPQREGSVKEEPVSEIQNRRSWQFDWALNKLDHSVRKTGRIPKTLLLKVFQETCREGCPGSNQTLLLLRSCGALLPEVLSSERTELAHMIWDKMKELGAVYDTSHYNALLKVYLQNEHKFSPTEFLARMEEANVQPNRVTYQRLIAAYCNEGDIEGASKILGFMKSKDLPITEAVFSSLVKGHARSGDIKSAENILSVMRMAGVEPGPDTYLSLLNVYAEKGDADSIKKTLEEVEKTEGYLMDRVLMQVIFSLAKAGYPQYIEDIKERMRFEKELIPDMMNLCLTLITHGFEDISFRILKSYNHLSRENVDQGSFFLQHCVNRNMPMSKLKQFCNELKEAKMHSAPLIFILRCALETNKSGLAIDVMRAMKEEGLPLRPHYCWPLLVGFQKEKNLKGVFEVLKVMHELGVELNAETYTDYVFKNFADIETACAQMKENNCLFETDGLFVAQIRHEAGHGRLKNVVSLLSSASTPSIDFRQFRNSLILGFRSSNDVQLWSQITELLYKDERYCLTPPGPTEAVGYFLYHLIDSMSDSEVQAKEERLRQYFHQLKKMNVVIPATYCSGICRLLDSSQVPELIKDVRSLSPKKFMSTEDIPDSAKSDVSALEKKLEKRKAENQPITDVLKQLIYALCEEENMQKALEVKAKYEPDMVVGGYAALINLCCRHDNVEEAMNLKEKVFPKSSPVALDSGKYIALVEVLAKRGRLEDAINVLREMKEKDVPISERAVASFFRLLNAAAIRGEVETVNRLHETIVNLGLAETAALYSPLITVHLEKDDMPAVLEALMDCYKKHGKILQLHNIYCRLIEKGDTELLRKVSDFISSEYGDMMALYDLFFAFLQTGKYKEARKVIETPGLRAHSGRLQWFAKRCISGNQMETLEHLVELTQNVFECDRDEMYYYLLQLCDNNSDWRRAEAVWTKIQEENVVPREKTLRLLADIFEKNGQVVPFEVPKTRQEEMRSPGSSDIEERKIRMLCKKNSAREAYNVFLKNQGKSDYQYRTYDTLIKALLSLDCIEEAMKVKHTAETHIKGFTLNSAASSLLIISQVRRDYLKDAVAAFQGMLDSGLLPSRPAVIALTQALAMKGDLRNLKALENMVESITQSIGLSPSLISNAIALAHTNNNDLDAAVEYLEPLLISGAQNPDQPVKNISFLLRKVSEKGLEPALEKFGVMAERLANQFGIYRPVTDLFLQYVSADRVDDARSLLQRCGGLVEEKRAFVNYMTKAASKPGQARKIEKLLELIPDSIDLETAYRHLIRCYELDGDVASVKAVYEKTKEKNIQLPELSLKSLAAFLKKAGEPVPFTEPPESFKFYVEEWRKRRLEAS", "length": 1418, "header": "tr|A0A8V0ZKH6-1|A0A8V0ZKH6_CHICK Isoform 1 of Leucine rich pentatricopeptide repeat containing OS=Gallus gallus OX=9031 GN=LRPPRC PE=1 SV=1 CANONICAL=A0A8V0ZKH6-1" }, "locus": { "chromosome": "3", "start_pos": 25033814, "end_pos": 24948580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049238.1", "url": "https://www.ensembl.org/id/ENSGALT00010049238.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029108.1", "url": "https://www.ensembl.org/id/ENSGALP00010029108.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 562, "start_aa": "Thr", "end_pos": 562, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr562", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 608, "start_aa": "Thr", "end_pos": 608, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr608", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421403", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421403", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1S5J1-1", "protein_name": "Leucine-rich PPR motif-containing protein, mitochondrial", "gene_name": "LRPPRC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAALLRPARWLLRARAAKSLPLSLRLLAGGPGRPHAAFCLPTGRARPVAGGLQSQVRLYTIAAEKKNYLQEEPASSHKRNASQFDWALMRLDNSVRRTGRIPKTLLQKVFDNTCHSGSPGSNQALLLLRSCGSLLPELKLSERMEFAHRIWDELQKLGTVYDISHYNALLKVYLQNEYKFSPTDFLAKMEKANIQPNRVTYQRLIAAYCNEGDIEGASKILGFMKTKDLPITEAVFSALVTGHARAGDMENAENILTVMKEAGIEPGPDTYLALLNAYAEKGDIDHVKQTLEKVEKSDHFLMDRDLLQIIFSFSKAGYPQYVSEILEKITYERRYIPDTMNLILLLVTEKLEDTALQILLACPVSREDSLSDFGSFFLRHCVTMNTPTEKLKDYCKKLKEARLHRSPFQFTLQCALLANKIDLAKSLMKALKEEGFPIRTHYFWPLLVGYQKEKNVQGIVEILKGMHELGVTPDQETYINYVFPCFDSIKSVRAVLQEHGCLHENTVFSQAELRSEAVNGNLDYILSFLESNTLPLSFTSLRGSLILGFRRSMDINLWSKITELLYKDGRYCQEPPGPTVECFLLFFSTEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLKEMNVKIPENIYKGIRNLLDSYHVPELIKDVNKLVEREKTDPQKTAQLTLSDLESKLEKLKSENQPIGDVLKHLILILCSEENMEKALELKAKYESDMVVGGYAALINLCCRHDNAEDALNLKREFDRLDSSAVLDTGKYLGLVKVLGKHGKLQDAINILKEMKEKDVLIKDATVLSFFHILNGAALRGETETVKQLHEAIVTLGLAKPSSSLSSPLVTLYLEKDDLPTALEVTIDCYEKYKVLPRIHDVLCRLIEKGKTELIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVETLEKLVELTQKLFECDRDQLYYNLLKLYKVNGDWQRADAVWNKMQEENIIPRGKTLRLLAEILRNSNQEVPFDVPELWYEDEQHSQISSASPEQGNLQKELLKACRKRKNRDAFNIFLKAKRQNIVFDDETYNTLIHFLLSKDNSVEAMQVKDFAETHIKGFTLNDAANSLLIITQVRRDYLKDALTTLKTALDLEQIPSRIAVTRLIQAYAMKGDTESIRAIQKLVNGLEDSIGLSRMVFINNIALAQIKNNDIDVAVENIENMLTSENPTMEPQYFGLAYLFRKVIEEQLEPALEKISIMAERLANQFAVYKPVTDLFLQLVDSGKVDDARALLQRCGAIAEQIPIFLVFCIRNSQRSGKASTMKSLLELIPELIDKEEAYTSIMKSYVLDKDVTSAKELYENLTAKDTKLNDLFLKRYAVLLKNAGESVPFTEPPESFEFYAKQLKESKENPL", "length": 1404 }, "evidence": [ { "id": "A0A8V0ZKH6", "url": "https://omabrowser.org/oma/group/A0A8V0ZKH6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P42704-1", "protein_name": "Leucine-rich PPR motif-containing protein, mitochondrial", "gene_name": "LRPPRC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALLRSARWLLRAGAAPRLPLSLRLLPGGPGRLHAASYLPAARAGPVAGGLLSPARLYAIAAKEKDIQEESTFSSRKISNQFDWALMRLDLSVRRTGRIPKKLLQKVFNDTCRSGGLGGSHALLLLRSCGSLLPELKLEERTEFAHRIWDTLQKLGAVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEEANIQPNRVTYQRLIASYCNVGDIEGASKILGFMKTKDLPVTEAVFSALVTGHARAGDMENAENILTVMRDAGIEPGPDTYLALLNAYAEKGDIDHVKQTLEKVEKSELHLMDRDLLQIIFSFSKAGYPQYVSEILEKVTCERRYIPDAMNLILLLVTEKLEDVALQILLACPVSKEDGPSVFGSFFLQHCVTMNTPVEKLTDYCKKLKEVQMHSFPLQFTLHCALLANKTDLAKALMKAVKEEGFPIRPHYFWPLLVGRRKEKNVQGIIEILKGMQELGVHPDQETYTDYVIPCFDSVNSARAILQENGCLSDSDMFSQAGLRSEAANGNLDFVLSFLKSNTLPISLQSIRSSLLLGFRRSMNINLWSEITELLYKDGRYCQEPRGPTEAVGYFLYNLIDSMSDSEVQAKEEHLRQYFHQLEKMNVKIPENIYRGIRNLLESYHVPELIKDAHLLVESKNLDFQKTVQLTSSELESTLETLKAENQPIRDVLKQLILVLCSEENMQKALELKAKYESDMVTGGYAALINLCCRHDKVEDALNLKEEFDRLDSSAVLDTGKYVGLVRVLAKHGKLQDAINILKEMKEKDVLIKDTTALSFFHMLNGAALRGEIETVKQLHEAIVTLGLAEPSTNISFPLVTVHLEKGDLSTALEVAIDCYEKYKVLPRIHDVLCKLVEKGETDLIQKAMDFVSQEQGEMVMLYDLFFAFLQTGNYKEAKKIIETPGIRARSARLQWFCDRCVANNQVETLEKLVELTQKLFECDRDQMYYNLLKLYKINGDWQRADAVWNKIQEENVIPREKTLRLLAEILREGNQEVPFDVPELWYEDEKHSLNSSSASTTEPDFQKDILIACRLNQKKGAYDIFLNAKEQNIVFNAETYSNLIKLLMSEDYFTQAMEVKAFAETHIKGFTLNDAANSRLIITQVRRDYLKEAVTTLKTVLDQQQTPSRLAVTRVIQALAMKGDVENIEVVQKMLNGLEDSIGLSKMVFINNIALAQIKNNNIDAAIENIENMLTSENKVIEPQYFGLAYLFRKVIEEQLEPAVEKISIMAERLANQFAIYKPVTDFFLQLVDAGKVDDARALLQRCGAIAEQTPILLLFLLRNSRKQGKASTVKSVLELIPELNEKEEAYNSLMKSYVSEKDVTSAKALYEHLTAKNTKLDDLFLKRYASLLKYAGEPVPFIEPPESFEFYAQQLRKLRENSS", "length": 1394 }, "evidence": [ { "id": "A0A8V0ZKH6", "url": "https://omabrowser.org/oma/group/A0A8V0ZKH6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5SGE0-1", "protein_name": "Leucine-rich PPR motif-containing protein, mitochondrial", "gene_name": "Lrpprc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSALLRPARWLLGAAAVPRLPLSLRLPAGGPGRLPSVVRVAAAGGRPAAGELLSQARLYAIVAEKKDLPEEPAPVRRSGSQFDWALMRLDNSVRRTGRITKGLLQKVFESTCRSGSPGSNQALLLLRSCGSLLPELSLAERTEFAHKIWDKLQQLGTVYDVSHYNALLKVYLQNEYRFSPTDFLAKMEGANIQPNRVTYQRLIAAYCSVGDIEGASKILGFMKTRDLPITEAVFSALVTGHARAGDMESAENILTVMKQAGIEPGPDTYLALLNAHAEKGDIDHVKQILEKVEKSDHYFMDRDFLQIIVSFSKAGYPQYVSEILEKITYERRSIPDAMNLILLLVTEKLEDTAFQVLLALPLARDETSSSFGSFFLRHCVTMDTPAEKLIDYCKRLRDAKVHSSSLQFTLHCALQANKTALAKAVMEALRDEGFPIRTHYFWPLLVGHQKTKNVQGIIDILKIMKEMGVDPDQETYINYVFPCFGSVQSARAALQENKCLPKSTTFAQAEVRNEAINGNLQNILSFLESNALPFSFNSLRGSLILGFRRSMNIDLWSKITELLYKDDRYCQKPPGPTEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLREMNVKVSENIYKGICNLLDNYHVPELIKDVKVLVDREKIDSRKTSQFTSSDLESTLEKLKAEGHPVGDPLKQLILLLCSEENMQKALEVKAKYESDMVIGGYAALINLCCRHDNAEDALNLKQEFDRLDPSAVLDTAKYVALVKVLGKHGRVQDAINILKEMKEKDVVIKDAAVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEKDDLPAALEASIACHEKYKVLPRIHDVLCKLIEKGETDLIQKAMDFVSQEQGEMSMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIANNQVETLEKLVELTEKLFECDRDQMYYNLLKLYKISGDWQRADAVWNKMQEENLIPRERTLRLLAGILKTSNQEVPFDVPELWFGDDRSSLSSSSPSAGDTVTEKMLLSDCRLKKSKDAYNIFLKAEKQDVVFSSEAYSTLVGLLLSKDDFTRAMHVKDFAETHIKGFTLNGAASSLLIIAQVRRDYLKVALETLKAALDLEQVPSELAVTRLIQALALQGDVKSIETIQKMVKGLDAIELSRMVFINNIALAQMKNNEIDAAIENIEHMLASENQTVEHQYFGLSYLFRKVIEEQMEPALEKLSIMSERLANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQTSILSVFCLRTSQKPKKAPVLKTLLELIPELRENDRVYSCSMKSYVADKDVASAKALYEHLTAKNMKLDDLFLKRYASLLKDVGEPVPFTEPPESFGFYIKQLKEARENPS", "length": 1392 }, "evidence": [ { "id": "A0A8V0ZKH6", "url": "https://omabrowser.org/oma/group/A0A8V0ZKH6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PB66-1", "protein_name": "Leucine-rich PPR motif-containing protein, mitochondrial", "gene_name": "Lrpprc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALLRPARWLLGAAAAPRLPLSLRLPAGVPGRLSSVVRVAAVGSRPAAGERLSQARLYAIVAEKRDLQEEPAPVRKNSSQFDWALMRLDNSVRRTGRITKGLLQRVFESTCSSGSPGSNQALLLLRSCGSLLPELSLAERTEFAHKIWDKLQQLGVVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEGANIQPNRVTYQRLIAAYCNVGDIEGASKILGFMKTKDLPITEAVFSALVTGHARAGDMENAENILTVMKQAGIEPGPDTYLALLNAHAERGDIGQVRQILEKVEKSDHYFMDRDFLQVIFSFSKAGYPQYVSEILEKITYERRSIPDAMNLILFLATEKLEDTAFQVLLALPLSKDESSDNFGSFFLRHCVTLDLPPEKLIDYCRRLRDAKLHSSSLQFTLHCALQANRTALAKAVMEALREEGFPIRPHYFWPLLAGHQKTKNVQGIIDILKIMNKVGVDPDQETYINYVFPCFDSAQSVRAALQENECLLASSTFAQAEVKNEAINGNLQNILSFLESNTLPFSFSSLRNSLILGFRRSMNIDLWSKITELLYKDERYCSKPPGPAEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLQEMNVKVPENIYKGICNLLNTYHVPELIKDIKVLVDREKVDSQKTSQVTSSDLESTLEKLKAEGQPVGSALKQLLLLLCSEENMQKALEVKAKYESDMVIGGYAALINLCCRHDNAEDAWNLKQEVDRLDASAILDTAKYVALVKVLGKHSRLQDAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEKGDLPAALEASIACHKKYKVLPRIHDVLCKLVEKGETDLIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVEALEKLVELTEKLFECDRDQMYYNLLKLYKISSDWQRADAAWTKMQEENIIPRERTLRLLAEILKTSNQEVPFDVPELWFGDDRPSLSPSSRSAGEDVTEKTLLSNCKLKKSKDAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDFTQAMHVKDFAETHIKGFTLNDAANSLLIIRQVRRDYLKGALATLRAALDLKQVPSQIAVTRLIQALALKGDVESIEAIQRMVAGLDTIGLSKMVFINNIALAQMKNNKLDAAIENIEHLLASENQAIEPQYFGLSYLFRKVIEEQMEPALEKLSIMSERMANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSLLSVFCLRTSQKPKKAPVLKTLLELIPELRDNDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLDDLFLKRYAALLKDVGEPVPFPEPPESFAFYIKQLKEARESPS", "length": 1392 }, "evidence": [ { "id": "A0A8V0ZKH6", "url": "https://omabrowser.org/oma/group/A0A8V0ZKH6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VJ86-1", "protein_name": "Leucine-rich PPR motif-containing protein, mitochondrial", "gene_name": "bsf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASILRTGKLLRYFAGFTRNVLVNSVRENETSNLLNNAPCMCGQFQNGFATNAAAKAELSLDKQIRRLDQDVRRIGRISRRDLEEVLDEIRSHRTATSSQSLLVIRCCGNLVPEELPEVRTALVQEIWKTLNALNVPMDISHYNALLRVYLENEHGFAPTDFLAEIEAKGIEPNRVTYQRLIARYCQQGDIEGATRILEFMRAKSLPVNENVFNSLILGHSQANDLESAKGILGVMMQAGLEPSADTYTTLLCAFARHGDLAAVKETLAECEQKEIILLDKDLLDIVYTLTVNGNGEHVDDVLTKLRLSPGFNQDAVNVILRLVNKGHEDVGLKLLRVMPRSSRVNGEPVDVGAFFIRQMVKANRPVEKILSICKSLQSEGLNPKALTIATEAGLTNGVINNALPLLQEMKNAGLPIRQHYFWPLICSAESNQVLEIVRRMQQEFSVFPNSETVRDYVIPNLKEKNWERIVTSLRDAGVPNSTAVTSAVYSALVTHQIAEAAKIMEKNRAYYVPFLFKQPLILALSHTNDYASFIRCVRQIHEGLQFRQGKDEEVEQVEGVAAVPTERITPDVVGAIVQEATTYFRRDRGATLEKILKGLVKQGLSISSDKATQLSEQLGSELTPKISELLGKLSSGELEPVPLPNSGKRSLDSLSINELERFIVNVEGKGENANNIKRQLLNACFRSQNLEKTLQVIEKLEAEKFQIPVGIYAQLIDLNTHHKKSSEALEIYGKLKAKDATFQLDNLKAVRLADLLLQEERVDAAFKILEENKKEVPVAEAEGSYNYMSTVWRILNSLAEAGQPERLRKLFDVLVGANYIVPTNVLLGPLIKVHLVKDDIPKAIEAFEEICQKYKSTPWKNELACRLIQKEDAANLQKLTDLSTGIHGEVNSLYDLVFSFVECGRVRQARKILETPGLRTRPQRINSACDRYKNEGLLQPLEGLIEATKDLGHIDRNKIYYTLLLSYDKADEAEKALGLWTKMQEENVTPNDAFLLKLAEILSKKNIDVPFVVPETQNEQAKAKKSKAKDATTTEAATETAKVAEQPKEKAAKKEPAKTETAKPPKTASHLSGFRKAIQANDPDAAISHKQSVLSGEKIGALDTSRLIELLVRADRLTEATKYVEELLGDKLHPQPKIFKFYLNKIAAAGDLETMQRIGQQLNDEQKRLISFDNRFCHANIVAGKAEEFLKHLTTEIDAAKTPEESTKLAEKFPRGGAVGILEKHPELVPQYQSLAEKFAAHNQLGPMNVLWMHLISTGQEAASKEIWDKHLSNAPRLMFQRVLQTAREQQDEKLASTVISQLKNSKISEGAIGNAYSCLIDIQTTKGNSDKAMVVLANAIKDVSLENINRTALLRLKQAVEEKSQKFPYTIPEKRTKADDSSSSSSSSSSDDDVSPSVPETVPPKPDSKA", "length": 1412 }, "evidence": [ { "id": "A0A8V0ZKH6", "url": "https://omabrowser.org/oma/group/A0A8V0ZKH6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" }, { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of mitochondrial translation", "id": "GO:0070129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070129", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" }, { "name": "mitochondrial mRNA polyadenylation", "id": "GO:0097222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" }, { "name": "negative regulation of mitochondrial mRNA catabolic process", "id": "GO:1905638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905638", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1241, "end_pos": 1243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH6" }, { "id": "PF23276", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23276" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mitochondrial 15S rRNA processing factor CCM1-like TPR repeats", "eco_id": "ECO_0000259", "start_pos": 260, "end_pos": 341, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 562, 608 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1241, "end_pos": 1243 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 999, "end_pos": 1001 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKZ2-1", "uniprot_ac": "A0A8V0ZKZ2", "uniprot_id": "A0A8V0ZKZ2_CHICK", "mass": { "chemical_mass": 573697.0, "monoisotopic_mass": 573697.0 }, "refseq": {}, "gene_names": [ { "name": "UBR4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2" } ] } ], "protein_names": [ { "name": "Ubiquitin protein ligase E3 component n-recognin 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2", "locus": { "chromosome": "21", "start_pos": 4585917, "end_pos": 4653584, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020517", "url": "https://www.ensembl.org/id/ENSGALG00010020517" } ] } } ], "crossref": [ { "id": "cd19680", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19680", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045189", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045189", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056530", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056530", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z7S9", "url": "https://www.orthodb.org/?gene=A0A8V0Z7S9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKZ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZKZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21725", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21725", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21725:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21725:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13764", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13764", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z7S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z7S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z7S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGGGAAEPGWEVAVRPLLSASYSAFEMKELPQLLASVIESESEILHHDKQYEPFYSSFVALSTHYITTVCGLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTIKTLSDVEDQKELASPVSPELRQKEVQMNFLNQLTSVFNPRVSASPSIMQETQVEGENEDQASADQTSAAKTKSIFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVSANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLTPTRLQDVTVLALSCLYAGVSVATCMAILHVGTTQQVRTGSTSSKEEDYENDAATIVQKCLEIYEMIGQAISNSRRAGGEHYQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLAALRVRDIIARTKEGVGSPKLGPGKGHQGFGVLSVVLANHAIKLLSSLFQDLQVEALHKGWESDGPPAVLDIMAQSTSIQRIQRLIDSVPLTNLLLTLLSTSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQWFEETISPSKEKVAPPPPPPPPPLESSPRVKSPNKQTAGENGNILASRKDPELFLSLASNILNFITSSMLNSRNNFIRNYLSVSLSEQHMATLASIIKEVDKDGLKGTSDEEFAAALYHFNHSLVTSDLQSPALQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKATAQGDPDVPECLKVWERFVGTLKQNALQGTLPSDAEDLNVEHLQLLLLIFHNFSERGRRSIMMLCIQTIVELTGNMDTQQSSVPLIVARLLLVFDYLLHQYSKAPVYLFEQVQYNLLTPPIGWVSGSQDSSRRTSVPLYHGFKEVEENWTKHCSSDAVPQPRFYCILSLEASEDDLNRLDSTVCEVLFSRTMKYDELYTALTSLLAAGSQFDTLRRKENKNVTALEACALQYYFLILWRILGILPPSKNYMNQLATNTPEMSECDILHTLRWSSRLRIPSYVTWIKDHLTKQGMKAEHAASLIELASSKCSSVKYDVEIAEEYFARQISSFCGIDCTTILQLHEVPSLQSIYTLDAAISKIQVSLDEHFTKLAAETDPHKSSEMTKNLLPATLQLIDTYATFTRSYLLRSLSEEGSSENKPSEEKLRGYAAVLAIGSSRCKSNTLGPMLVQNLPSAVQTLCDSWNNIHTNEFPNIGSWRNAFANDTIPAESYISAVQAAHLGTLCSQSLPLAASLKHTLLSLVRLTGDLIVWSDDLNPPQVIHSLLPLLLETSTESVAEISSNSLERILGPAESDEFLARVYEKLITGCYNILAHHSDPNSGLDESILEECLQHLEKQLESSQARKAMEEFFSESGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLRLCGSLAQLACVEPIRLQAWLTRMTMSPPKDSDQLDVVQENRQLLQLLTTYIVRENSQVGEGVCTVLLSTLIPMATEMLANGDGTGFPELMVVMATLASAGQGAGHLQLHGAAVDWLGKCKKYLSQKNVVEKMNANVMQGKHVTILECTCHIVSYLADVTNALSQTSGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQSEPRVPESVIRHASTSPAEKAKVTISEGKGPDEEKPKKSSLCRNVEGCREELQSQANFSFAPLVLEMLNFLMDAIQINFQQASAMGSSSRAQQALNELHTLDKSVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQHGPFYVTNVLEVNHEDLKDSNGQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRASLEVQRLFPINIKSSNGGSKTSPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKAAAITTRTSSQVNFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEVTNNNSTMVMTGMRIQIGTQAIERAPSYLEIFGRTMQLNLTRARWFDFPFTREEALQADKKLTFFIGASVDPAGVTMLDSIKIYGKTKEQFGWPDEPPEDFPSASVSNVCPPNLNQGNGTGDTESATPAATSGTVLESSETESLTTLDRLVVSSLEALESCFAVGPVNEKEKNKAAAQELATMLLSMPAPSSVQQQTKSLLASLHTSRSAYHNHKDQALLSKAIQYLSSSTKEGKDLDPEVFQRLVITARSIAIMRPNNLVHYTESKLSQLETESEEGQEAQKHAEGEGCTFITQLVNHFWKLHASKPKNAFLAPACLPGLTHVEATVNALVDIIHGYCTCELDCIHTASKIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDAEDKLQSSGIANGEHIRQESQEQSEVDHGDFEMVSESMVLETSENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASALFILLAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDTTAEGHPAGPGSVSSSTGAISTTTGQQEGDGSEGEGEAEGDVHTSNRLHMVRLMLLERLLQNLPQLRNVGGVRAIPYMQVILMLTTDLDGDDEKDKGALDNLLSQLIAELCMEKKDVSKKNERSPVNEVHLVVMRLLSVFMSRTKSGSKSSICESSSLISSATAAALLSSGAVDYCLHVLKSLLEYWKSQQNDEEPVATSQLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKDKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIATQRTVNWQKFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLSVASSSGSSSTSSTSAPAASGSGQPATQSKSSTKKSKKEEKEKEREGESSGSQEDQLCTALVNQLNKFADKETLIQFLRCFLLESNSSSVRWQAHCLALHIYRNSNKSQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTQQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVTNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDESGSSGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTTVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNSAIRHILVSQGLIRELFDYNLRRGAATMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSAALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPADALTTVKPYSNEIHAQAQLWLKRDPKASYEAWKKCLPARGVDANGKSPSKAELHQLYLSEKYVWKWKQFMSRRGKRTCPLDLKLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLDELSIAGECAAEYLALYQKLIKPAHWKVYLAARGVLPYIGSLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYSLDDYRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCPTNEGEPMRIIYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLTGIKDFKQGRHLLTVLLKLFSYCVKVKINRQQLVKPEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNLSVLQGLLRIIPYLSFGEMEKMQILVDRFKPYCNFDKYDEEHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIPSAKNLDADIWKKFLSRPALPFILRLLRGLATQHPATQVLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHPEVNKKIDAARKETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEFENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNVHDIKLLFLRFAMEQSFSVDTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQSFMEHPKEKWLESAYEVDGPHYYTVLALHISPPEKWKAMRVEILKRLLVTSHARVVSPGGASRLADKAVKEYATYRSGLLFWALVDLIYNMFKKVPTSNTEGGWSYSLAEFIRHNDMPIHEAADKALKTFQEEFMPVETFSEFLDVAGLLSEISDPDSFLRDLLNSIP", "length": 5177, "header": "tr|A0A8V0ZKZ2-1|A0A8V0ZKZ2_CHICK Isoform 1 of Ubiquitin protein ligase E3 component n-recognin 4 OS=Gallus gallus OX=9031 GN=UBR4 PE=1 SV=1 CANONICAL=A0A8V0ZKZ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z7S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2/entry#A0A8V0Z7S9-1", "sequence": { "sequence": "MAAGGGAAEPGWEVAVRPLLSASYSAFEMKELPQLLASVIESESEILHHDKQYEPFYSSFVALSTHYITTVCGLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTIKTLSDVEDQKELASPVSPELRQKEVQMNFLNQLTSVFNPRVSASPSIMQETQVEGENEDQASADQTSAAKTKSIFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVSANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLTPTRLQDVTVLALSCLYAGVSVATCMAILHVGTTQQVRTGSTSSKEEDYENDAATIVQKCLEIYEMIGQAISNSRRAGGEHYQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLAALRVRDIIARTKEGVGSPKLGPGKGHQGFGVLSVVLANHAIKLLSSLFQDLQVEALHKGWESDGPPAVLDIMAQSTSIQRIQRLIDSVPLTNLLLTLLSTSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQWFEETISPSKEKVAPPPPPPPPPLESSPRVKSPNKQTAGENGNILASRKDPELFLSLASNILNFITSSMLNSRNNFIRNYLSVSLSEQHMATLASIIKEVDKDGLKGTSDEEFAAALYHFNHSLVTSDLQSPALQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKATAQGDPDVPECLKVWERFVGTLKQNALQGTLPSDAEDLNVEHLQLLLLIFHNFSERGRRSIMMLCIQTIVELTGNMDTQQSSVPLIVARLLLVFDYLLHQYSKAPVYLFEQVQYNLLTPPIGWVSGSQDSSRRTSVPLYHGFKEVEENWTKHCSSDAVPQPRFYCILSLEASEDDLNRLDSTVCEVLFSRTMKYDELYTALTSLLAAGSQFDTLRRKENKNVTALEACALQYYFLILWRILGILPPSKNYMNQLATNTPEMSECDILHTLRWSSRLRIPSYVTWIKDHLTKQGMKAEHAASLIELASSKCSSVKYDVEIAEEYFARQISSFCGIDCTTILQLHEVPSLQSIYTLDAAISKIQVSLDEHFTKLAAETDPHKSSEMTKNLLPATLQLIDTYATFTRSYLLRSLSEEGSSENKPSEEKLRGYAAVLAIGSSRCKSNTLGPMLVQNLPSAVQTLCDSWNNIHTNEFPNIGSWRNAFANDTIPAESYISAVQAAHLGTLCSQSLPLAASLKHTLLSLVRLTGDLIVWSDDLNPPQVIHSLLPLLLETSTESVAEISSNSLERILGPAESDEFLARVYEKLITGCYNILAHHSDPNSGLDESILEECLQHLEKQLESSQARKAMEEFFSESGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLRLCGSLAQLACVEPIRLQAWLTRMTMSPPKDSDQLDVVQENRQLLQLLTTYIVRENSQVGEGVCTVLLSTLIPMATEMLANGDGTGFPELMVVMATLASAGQGAGHLQLHGAAVDWLGKCKKYLSQKNVVEKMNANVMQGKHVTILECTCHIVSYLADVTNALSQTSGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQSEPRVPESVIRHASTSPAEKAKVTISEGKGPDEEKPKKSSLCRNVEGCREELQSQANFSFAPLVLEMLNFLMDAIQINFQQASAMGSSSRAQQALNELHTLDKSVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQHGPFYVTNVLEVNHEDLKDSNGQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRASLEVQRLFPINIKSSNGGSKTSPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKAAAITTRTSSQVNFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEVTNNNSTMVMTGMRIQIGTQAIERAPSYLEIFGRTMQLNLTRARWFDFPFTREEALQADKKLTFFIGASVDPAGVTMLDSIKIYGKTKEQFGWPDEPPEDFPSASVSNVCPPNLNQGNGTGDTESATPAATSGTVLERLVVSSLEALESCFAVGPVNEKEKNKAAAQELATMLLSMPAPSSVQQQTKSLLASLHTSRSAYHNHKDQALLSKAIQYLSSSTKEGKDLDPEVFQRLVITARSIAIMRPNNLVHYTESKLSQLETESEEGQEAQKHAEGEGCTFITQLVNHFWKLHASKPKNAFLAPACLPGLTHVEATVNALVDIIHGYCTCELDCIHTASKIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDAEDKLQSSGIANGEHIRQESQEQSEVDHGDFEMVSESMVLETSENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASALFILLAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDTTAEGHPAGPGSVSSSTGAISTTTGQQEGDGSEGEGEAEGDVHTSNRLHMVRLMLLERLLQNLPQLRNVGGVRAIPYMQVILMLTTDLDGDDEKDKGALDNLLSQLIAELCMEKKDVSKKNERSPVNEVHLVVMRLLSVFMSRTKSGSKSSICESSSLISSATAAALLSSGAVDYCLHVLKSLLEYWKSQQNDEEPVATSQLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKDKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIATQRTVNWQKFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLSVASSSGSSSTSSTSAPAASGSGQPATQSKSSTKKSKKEEKEKEREGESSGSQEDQLCTALVNQLNKFADKETLIQFLRCFLLESNSSSVRWQAHCLALHIYRNSNKSQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTQQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVTNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDESGSSGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTTVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNSAIRHILVSQGLIRELFDYNLRRGAATMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSAALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPADALTTVKPYSNEIHAQAQLWLKRDPKASYEAWKKCLPARGVDANGKSPSKAELHQLYLSEKYVWKWKQFMSRRGKRTCPLDLKLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLDELSIAGECAAEYLALYQKLIKPAHWKVYLAARGVLPYIGSLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYSLDDYRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCPTNEGEPMRIIYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLTGIKDFKQGRHLLTVLLKLFSYCVKVKINRQQLVKPEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNLSVLQGLLRIIPYLSFGEMEKMQILVDRFKPYCNFDKYDEEHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIPSAKNLDADIWKKFLSRPALPFILRLLRGLATQHPATQVLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHPEVNKKIDAARKETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEFENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNVHDIKLLFLRFAMEQSFSVDTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQSFMEHPKEKWLESAYEVDGPHYYTVLALHISPPEKWKAMRVEILKRLLVTSHARVVSPGGASRLADKAVKEYATYRSGLLFWALVDLIYNMFKKVPTSNTEGGWSYSLAEFIRHNDMPIHEAADKALKTFQEEFMPVETFSEFLDVAGLLSEISDPDSFLRDLLNSIP", "length": 5166, "header": "tr|A0A8V0Z7S9-1|A0A8V0ZKZ2_CHICK Computationally mapped isoform of Ubiquitin protein ligase E3 component n-recognin 4 OS=Gallus gallus OX=9031 GN=UBR4 PE=1 SV=1 CANONICAL=A0A8V0ZKZ2-1" }, "locus": { "chromosome": "21", "start_pos": 4653568, "end_pos": 4586304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049596.1", "url": "https://www.ensembl.org/id/ENSGALT00010049596.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029299.1", "url": "https://www.ensembl.org/id/ENSGALP00010029299.1" } ] } }, { "isoform_ac": "A0A8V0ZKZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2/entry#A0A8V0ZKZ2-1", "sequence": { "sequence": "MAAGGGAAEPGWEVAVRPLLSASYSAFEMKELPQLLASVIESESEILHHDKQYEPFYSSFVALSTHYITTVCGLIPRNQLQSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTIKTLSDVEDQKELASPVSPELRQKEVQMNFLNQLTSVFNPRVSASPSIMQETQVEGENEDQASADQTSAAKTKSIFIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVSANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLPVLEPLTPTRLQDVTVLALSCLYAGVSVATCMAILHVGTTQQVRTGSTSSKEEDYENDAATIVQKCLEIYEMIGQAISNSRRAGGEHYQNFQLLGAWCLLNSLFLILNLSPTALADKGKEKDPLAALRVRDIIARTKEGVGSPKLGPGKGHQGFGVLSVVLANHAIKLLSSLFQDLQVEALHKGWESDGPPAVLDIMAQSTSIQRIQRLIDSVPLTNLLLTLLSTSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQWFEETISPSKEKVAPPPPPPPPPLESSPRVKSPNKQTAGENGNILASRKDPELFLSLASNILNFITSSMLNSRNNFIRNYLSVSLSEQHMATLASIIKEVDKDGLKGTSDEEFAAALYHFNHSLVTSDLQSPALQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKATAQGDPDVPECLKVWERFVGTLKQNALQGTLPSDAEDLNVEHLQLLLLIFHNFSERGRRSIMMLCIQTIVELTGNMDTQQSSVPLIVARLLLVFDYLLHQYSKAPVYLFEQVQYNLLTPPIGWVSGSQDSSRRTSVPLYHGFKEVEENWTKHCSSDAVPQPRFYCILSLEASEDDLNRLDSTVCEVLFSRTMKYDELYTALTSLLAAGSQFDTLRRKENKNVTALEACALQYYFLILWRILGILPPSKNYMNQLATNTPEMSECDILHTLRWSSRLRIPSYVTWIKDHLTKQGMKAEHAASLIELASSKCSSVKYDVEIAEEYFARQISSFCGIDCTTILQLHEVPSLQSIYTLDAAISKIQVSLDEHFTKLAAETDPHKSSEMTKNLLPATLQLIDTYATFTRSYLLRSLSEEGSSENKPSEEKLRGYAAVLAIGSSRCKSNTLGPMLVQNLPSAVQTLCDSWNNIHTNEFPNIGSWRNAFANDTIPAESYISAVQAAHLGTLCSQSLPLAASLKHTLLSLVRLTGDLIVWSDDLNPPQVIHSLLPLLLETSTESVAEISSNSLERILGPAESDEFLARVYEKLITGCYNILAHHSDPNSGLDESILEECLQHLEKQLESSQARKAMEEFFSESGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLRLCGSLAQLACVEPIRLQAWLTRMTMSPPKDSDQLDVVQENRQLLQLLTTYIVRENSQVGEGVCTVLLSTLIPMATEMLANGDGTGFPELMVVMATLASAGQGAGHLQLHGAAVDWLGKCKKYLSQKNVVEKMNANVMQGKHVTILECTCHIVSYLADVTNALSQTSGQGPSHLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTMKESAFQSEPRVPESVIRHASTSPAEKAKVTISEGKGPDEEKPKKSSLCRNVEGCREELQSQANFSFAPLVLEMLNFLMDAIQINFQQASAMGSSSRAQQALNELHTLDKSVEMTDQLMVPTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTFSSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYFLLPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQHGPFYVTNVLEVNHEDLKDSNGQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRASLEVQRLFPINIKSSNGGSKTSPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKAAAITTRTSSQVNFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEVTNNNSTMVMTGMRIQIGTQAIERAPSYLEIFGRTMQLNLTRARWFDFPFTREEALQADKKLTFFIGASVDPAGVTMLDSIKIYGKTKEQFGWPDEPPEDFPSASVSNVCPPNLNQGNGTGDTESATPAATSGTVLESSETESLTTLDRLVVSSLEALESCFAVGPVNEKEKNKAAAQELATMLLSMPAPSSVQQQTKSLLASLHTSRSAYHNHKDQALLSKAIQYLSSSTKEGKDLDPEVFQRLVITARSIAIMRPNNLVHYTESKLSQLETESEEGQEAQKHAEGEGCTFITQLVNHFWKLHASKPKNAFLAPACLPGLTHVEATVNALVDIIHGYCTCELDCIHTASKIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDAEDKLQSSGIANGEHIRQESQEQSEVDHGDFEMVSESMVLETSENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASALFILLAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDTTAEGHPAGPGSVSSSTGAISTTTGQQEGDGSEGEGEAEGDVHTSNRLHMVRLMLLERLLQNLPQLRNVGGVRAIPYMQVILMLTTDLDGDDEKDKGALDNLLSQLIAELCMEKKDVSKKNERSPVNEVHLVVMRLLSVFMSRTKSGSKSSICESSSLISSATAAALLSSGAVDYCLHVLKSLLEYWKSQQNDEEPVATSQLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKDKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIATQRTVNWQKFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLSVASSSGSSSTSSTSAPAASGSGQPATQSKSSTKKSKKEEKEKEREGESSGSQEDQLCTALVNQLNKFADKETLIQFLRCFLLESNSSSVRWQAHCLALHIYRNSNKSQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTQQTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVTNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQDESGSSGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAATKSSRTTVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNSAIRHILVSQGLIRELFDYNLRRGAATMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSAALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPADALTTVKPYSNEIHAQAQLWLKRDPKASYEAWKKCLPARGVDANGKSPSKAELHQLYLSEKYVWKWKQFMSRRGKRTCPLDLKLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLDELSIAGECAAEYLALYQKLIKPAHWKVYLAARGVLPYIGSLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYSLDDYRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCPTNEGEPMRIIYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLTGIKDFKQGRHLLTVLLKLFSYCVKVKINRQQLVKPEMNTLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNLSVLQGLLRIIPYLSFGEMEKMQILVDRFKPYCNFDKYDEEHSGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIPSAKNLDADIWKKFLSRPALPFILRLLRGLATQHPATQVLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREHPEVNKKIDAARKETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEFENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNVHDIKLLFLRFAMEQSFSVDTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQSFMEHPKEKWLESAYEVDGPHYYTVLALHISPPEKWKAMRVEILKRLLVTSHARVVSPGGASRLADKAVKEYATYRSGLLFWALVDLIYNMFKKVPTSNTEGGWSYSLAEFIRHNDMPIHEAADKALKTFQEEFMPVETFSEFLDVAGLLSEISDPDSFLRDLLNSIP", "length": 5177, "header": "tr|A0A8V0ZKZ2-1|A0A8V0ZKZ2_CHICK Isoform 1 of Ubiquitin protein ligase E3 component n-recognin 4 OS=Gallus gallus OX=9031 GN=UBR4 PE=1 SV=1 CANONICAL=A0A8V0ZKZ2-1" }, "locus": { "chromosome": "21", "start_pos": 4653568, "end_pos": 4586304, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049581.1", "url": "https://www.ensembl.org/id/ENSGALT00010049581.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029290.1", "url": "https://www.ensembl.org/id/ENSGALP00010029290.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2447, "start_aa": "Thr", "end_pos": 2447, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2447", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": 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"MVLATASPRSQGTIDELEEKLSLCRQSMEEVDLKLRGEKLSHEGRKSLERERNLLMTKADNYEKELSVLRKENRKNAALAVAMVLLIALIYTCWTM", "length": 96, "header": "tr|A0A8V0Z7T4-1|A0A8V0ZL03_CHICK Computationally mapped isoform of Coiled-coil domain-containing protein 167 OS=Gallus gallus OX=9031 GN=CCDC167 PE=4 SV=1 CANONICAL=A0A8V0ZL03-1" }, "locus": { "chromosome": "3", "start_pos": 29845415, "end_pos": 29830630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049604.1", "url": "https://www.ensembl.org/id/ENSGALT00010049604.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029304.1", "url": "https://www.ensembl.org/id/ENSGALP00010029304.1" } ] } }, { "isoform_ac": "A0A8V0ZL03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL03/entry#A0A8V0ZL03-1", "sequence": { "sequence": "MRRLLGEGFSSLPPPLRLALISSMRVRRRKPHYLTLLDVNIDELEEKLSLCRQSMEEVDLKLRGEKLSHEGRKSLERERNLLMTKADNYEKELSVLRKENRKNAALAVAMVLLIALIYTCWTM", "length": 123, "header": "tr|A0A8V0ZL03-1|A0A8V0ZL03_CHICK Isoform 1 of Coiled-coil domain-containing protein 167 OS=Gallus gallus OX=9031 GN=CCDC167 PE=4 SV=1 CANONICAL=A0A8V0ZL03-1" }, "locus": { "chromosome": "3", "start_pos": 29845415, "end_pos": 29839213, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049597.1", "url": "https://www.ensembl.org/id/ENSGALT00010049597.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029300.1", "url": "https://www.ensembl.org/id/ENSGALP00010029300.1" } ] } }, { "isoform_ac": "F1NAT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL03/entry#F1NAT1-1", "sequence": { "sequence": "MGKKREGLSVAREIDELEEKLSLCRQSMEEVDLKLRGEKLSHEGRKSLERERNLLMTKADNYEKELSVLRKENRKNAALAVAMVLLIALIYTCWTM", "length": 96, "header": "tr|F1NAT1-1|A0A8V0ZL03_CHICK Computationally mapped isoform of Coiled-coil domain-containing protein 167 OS=Gallus gallus OX=9031 GN=CCDC167 PE=4 SV=3 CANONICAL=A0A8V0ZL03-1" }, "locus": { "chromosome": "3", "start_pos": 29845415, "end_pos": 29837893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049600.1", "url": "https://www.ensembl.org/id/ENSGALT00010049600.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029302.1", "url": "https://www.ensembl.org/id/ENSGALP00010029302.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421433", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421433", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AUD4-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "CCDC167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTKKKRENLGVALEIDGLEEKLSQCRRELEAVNSRLYGAELSPEARRSLEKEKSSLMSKASNYEKELKLLRQENRKNMLLSVVIFILLTFLYAYWTT", "length": 97 }, "evidence": [ { "id": "A0A8V0ZL03", "url": "https://omabrowser.org/oma/group/A0A8V0ZL03/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7IER4-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "Ccdc167", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTKKKRENLGVAQEIDGLEEKLSQCRKDLEAVTSQLYRTELSPEDRRSLEKEKTTLMSKASKYEKELKLLRQENRKNMLLSVAIFILLALLYAHWTM", "length": 97 }, "evidence": [ { "id": "A0A8V0ZL03", "url": "https://omabrowser.org/oma/group/A0A8V0ZL03/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0M027-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "Ccdc167", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKKRENLGVAREIDGLEEKLSQCRKDLEAVTSQLHRAELSPEDRRSLEKEKNALMNKASKYEKELKLLRQENQKNMLLSVAIFIVFALLYAYWTMHESSCPPCPPCPGAQAHRWLKCCSRTSLPFSTRTSRMWIALIFRWAFPYNDKHAVRWAGRPALPALCALLVSKCLCLSRGKVASGLEQRLD", "length": 188 }, "evidence": [ { "id": "A0A8V0ZL03", "url": "https://omabrowser.org/oma/group/A0A8V0ZL03/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1A4P9-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "CCDC167", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTKKKRENLGVALEIDGLEKKLSQCRRDLEVVNSRLCGVELSSEARRSLEKEKSSLMNKASNYEKELKLLRQENRKNMLLSVAIFLLLTVIYAYWAL", "length": 97 }, "evidence": [ { "id": "A0A8V0ZL03", "url": "https://omabrowser.org/oma/group/A0A8V0ZL03/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5RHZ2-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "ccdc167", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTRTRTVKKEKISVASEIDRVEERKLQCKNSLERAEFRKRKQQLSDDDRLALEDEMTILNERVEKYEKDLQVLRGENRRNMMLSVALLAISALFYYTFIY", "length": 100 }, "evidence": [ { "id": "A0A8V0ZL03", "url": "https://omabrowser.org/oma/group/A0A8V0ZL03/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D162-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "Ccdc167", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKKKRENLGVAQEIDGLEEKLSRCRKDLEAVTSQLYRAELSPEDRRSLEKEKHTLMNKASKYEKELKLLRHENRKNTLLSVAIFTVFALLYAYWTM", "length": 97 }, "evidence": [ { "id": "A0A8V0ZL03", "url": "https://omabrowser.org/oma/group/A0A8V0ZL03/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P0B6-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "CCDC167", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKKKRENLGVALEIDGLEEKLSQCRRDLEAVNSRLHSRELSPEARRSLEKEKNSLMNKASNYEKELKFLRQENRKNMLLSVAIFILLTLVYAYWTM", "length": 97 }, "evidence": [ { "id": "A0A8V0ZL03", "url": "https://omabrowser.org/oma/group/A0A8V0ZL03/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLR8-1", "uniprot_ac": "A0A8V0ZLR8", "uniprot_id": "A0A8V0ZLR8_CHICK", "mass": { "chemical_mass": 109543.0, "monoisotopic_mass": 109543.0 }, "refseq": { "ac": "XP_004945148", "name": "zinc finger CCCH domain-containing protein 7A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945148" }, "gene_names": [ { "name": "ZC3H7A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8" } ] }, { "name": "ZC3H7A", "type": "synonym", "evidence": [ { "id": "XP_004945148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945148" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH-type containing 7A", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCCH domain-containing protein 7A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004945148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945148" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945148.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945148" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZC3H7A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8", "locus": { "chromosome": "14", "start_pos": 898703, "end_pos": 873142, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020712", "url": "https://www.ensembl.org/id/ENSGALG00010020712" } ] } } ], "crossref": [ { "id": "A0A8V0ZLR8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLR8", "database": "AlphaFoldDB", "categories": [] }, { "id": "416426", "url": "https://www.ncbi.nlm.nih.gov/gene/416426", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416426", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416426", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ICERYMN", "url": "https://omabrowser.org/oma/group/ICERYMN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8I8", "url": "https://www.orthodb.org/?gene=A0A8V0Z8I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLR8", "url": "https://www.orthodb.org/?gene=A0A8V0ZLR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14928", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14928", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14928:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14928:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945148", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8I8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNVSEERSTRQQDIKKGLQFIESTLPYPGTQEQYELFIRELVRNLFNEGNDVYREGDWRGSLNHYSEAINIADYANSEEIHVSDDILEKLHVNRIACFSNMGLHEKVLEDCEIALRLNENNFRALYRKAKALNELGRYKTAYDAVAKCSLAVPQDESVIKLTQELAQKLGLKIRKAYVRAKPPSNSVSSDISTQNSSSVEDIELDLSDQKQDTVSSASSSAFVSELSKVASVPISSLSSVMSLQAEKASLPSAALANGGNVSFSMPEACLDCGDGDIIIGEELDELLDSVPDPDESVMQTTGARGPIPAGGVGPSVPFSASLLGTLPVSTGFVPPPSLSEIFSQPLASSLENFCSPLSTFSISDPKRDLSSSASRDGTPTLSSSNSPLFINGPSSLFGSENYMGISGQTRNDFSNVFSSATASIPASSALVGRNPLEGTHELRQACQLCFVKKGPKLLDYAYHPNLEHKCKKDILIGRIKNSEDKSWKKIRPRPTKTQYVGPYYICKDVAAEEECRYPGHCTFAYCQEEIDVWTLERKGAFSREALFGGNGKINFTVSRLLQEHHGFFMFLCEKCFDHKPRIISKRNKDNSSSCSHPAMHDFEDNKCLVHILRETMVKYSKIRPFQVRCQLDLCRHEVHYGCLREDKCFYAHSLVELKVWIMQKETGISHDAIVQESKKYWQNMEASAHGSQILGNQMKYGSLNLKMKFVCGQCWRNGQVNEPDRNKKYCSAKARHPWTKDRRVVLVMSNERKKWMTIRPLPAKKQVPLQFDLCNHIASGKKCQYDGNCSFAHSPEEREMWTYMKENSIQDLEQLYDIWLKSQKPEKGDDTAAQANKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQNCWQYRFPTGCFSICDRYMAGTCTEGNNCKFAHGNAELHEWEERRQVLRMKLSKARKDHLIAPSDNDFGKYSFLFKGLD", "length": 971, "header": "tr|A0A8V0ZLR8-1|A0A8V0ZLR8_CHICK Isoform 1 of Zinc finger CCCH-type containing 7A OS=Gallus gallus OX=9031 GN=ZC3H7A PE=4 SV=1 CANONICAL=A0A8V0ZLR8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8/entry#A0A8V0Z8I8-1", "sequence": { "sequence": "MSNVSEERSTRQQDIKKGLQFIESTLPYPGTQEQYELFIRELVRNLFNEGNDVYREGDWRGSLNHYSEAINIADYANSEEIHVSDDILEKLHVNRIACFSNMGLHEKVLEDCEIALRLNENNFRALYRKAKALNELGRYKTAYDAVAKCSLAVPQDESVIKLTQELAQKLGLKIRKAYVRAKPPSNSVSSDISTQNSSSVEDIELDLSDQKQDTVSSASSSAFVSELSKVASVPISSLSSVMSLQAEKASLPSAALANGGNVSFSMPEACLDCGDGDIIIGEELDELLDSVPDPDESVMQTTGARGPIPAGEIFSQPLASSLENFCSPLSTFSISDPKRDLSSSASRDGTPTLSSSNSPLFINGPSSLFGSENYMGISGQTRNDFSNVFSSATASIPASSALVGRNPLEGTHELRQACQLCFVKKGPKLLDYAYHPNLEHKCKKDILIGRIKNSEDKSWKKIRPRPTKTQYVGPYYICKDVAAEEECRYPGHCTFAYCQEEIDVWTLERKGAFSREALFGGNGKINFTVSRLLQEHHGFFMFLCEKCFDHKPRIISKRNKDNSSSCSHPAMHDFEDNKCLVHILRETMVKYSKIRPFQVRCQLDLCRHEVHYGCLREDKCFYAHSLVELKVWIMQKETGISHDAIVQESKKYWQNMEASAHGSQILGNQMKYGSLNLKMKFVCGQCWRNGQVNEPDRNKKYCSAKARHPWTKDRRVVLVMSNERKKWMTIRPLPAKKQVPLQFDLCNHIASGKKCQYDGNCSFAHSPEEREMWTYMKENSIQDLEQLYDIWLKSQKPEKGDDTAAQANKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQNCWQYRFPTGCFSICDRYMAGTCTEGNNCKFAHGNAELHEWEERRQVLRMKLSKARKDHLIAPSDNDFGKYSFLFKGLD", "length": 942, "header": "tr|A0A8V0Z8I8-1|A0A8V0ZLR8_CHICK Computationally mapped isoform of Zinc finger CCCH-type containing 7A OS=Gallus gallus OX=9031 GN=ZC3H7A PE=4 SV=1 CANONICAL=A0A8V0ZLR8-1" }, "locus": { "chromosome": "14", "start_pos": 897979, "end_pos": 877580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050048.1", "url": "https://www.ensembl.org/id/ENSGALT00010050048.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029570.1", "url": "https://www.ensembl.org/id/ENSGALP00010029570.1" } ] } }, { "isoform_ac": "A0A8V0ZLR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8/entry#A0A8V0ZLR8-1", "sequence": { "sequence": "MSNVSEERSTRQQDIKKGLQFIESTLPYPGTQEQYELFIRELVRNLFNEGNDVYREGDWRGSLNHYSEAINIADYANSEEIHVSDDILEKLHVNRIACFSNMGLHEKVLEDCEIALRLNENNFRALYRKAKALNELGRYKTAYDAVAKCSLAVPQDESVIKLTQELAQKLGLKIRKAYVRAKPPSNSVSSDISTQNSSSVEDIELDLSDQKQDTVSSASSSAFVSELSKVASVPISSLSSVMSLQAEKASLPSAALANGGNVSFSMPEACLDCGDGDIIIGEELDELLDSVPDPDESVMQTTGARGPIPAGGVGPSVPFSASLLGTLPVSTGFVPPPSLSEIFSQPLASSLENFCSPLSTFSISDPKRDLSSSASRDGTPTLSSSNSPLFINGPSSLFGSENYMGISGQTRNDFSNVFSSATASIPASSALVGRNPLEGTHELRQACQLCFVKKGPKLLDYAYHPNLEHKCKKDILIGRIKNSEDKSWKKIRPRPTKTQYVGPYYICKDVAAEEECRYPGHCTFAYCQEEIDVWTLERKGAFSREALFGGNGKINFTVSRLLQEHHGFFMFLCEKCFDHKPRIISKRNKDNSSSCSHPAMHDFEDNKCLVHILRETMVKYSKIRPFQVRCQLDLCRHEVHYGCLREDKCFYAHSLVELKVWIMQKETGISHDAIVQESKKYWQNMEASAHGSQILGNQMKYGSLNLKMKFVCGQCWRNGQVNEPDRNKKYCSAKARHPWTKDRRVVLVMSNERKKWMTIRPLPAKKQVPLQFDLCNHIASGKKCQYDGNCSFAHSPEEREMWTYMKENSIQDLEQLYDIWLKSQKPEKGDDTAAQANKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQNCWQYRFPTGCFSICDRYMAGTCTEGNNCKFAHGNAELHEWEERRQVLRMKLSKARKDHLIAPSDNDFGKYSFLFKGLD", "length": 971, "header": "tr|A0A8V0ZLR8-1|A0A8V0ZLR8_CHICK Isoform 1 of Zinc finger CCCH-type containing 7A OS=Gallus gallus OX=9031 GN=ZC3H7A PE=4 SV=1 CANONICAL=A0A8V0ZLR8-1" }, "locus": { "chromosome": "14", "start_pos": 897979, "end_pos": 877580, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050049.1", "url": "https://www.ensembl.org/id/ENSGALT00010050049.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029571.1", "url": "https://www.ensembl.org/id/ENSGALP00010029571.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416426", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416426", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B4P9-1", "protein_name": "Zinc finger CCCH-type containing 7A", "gene_name": "ZC3H7A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSVSEERRKRQQNIQEGLQFIQSPLSYPGTQEQYAVYLGALVRNLFNEGNDVYRERDWNSSVSQYSEALSIADYAKSEEILIPKEIIEKLHINRIACYSIMGFHDKVLEDCETVLSLNASNCKALYRKSKALSDLGRYKEAYDAVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAELSLKSVPGDGAAKALNCSVEDIEPDLLTPRQEAVPVVSIPTSSFSHQVGSELASVPVMPIASVLPLPVEESSLPSTVLANGGKIPFVMPEPFLDDGDMVLGDEIDELLDSAPETNENVMPSALVRGPLSTATVTPNIPFSASLLGTLPIGARYAPAPSFSELFPPLASSLEDFCSSLKSFSMSESKRDLSTSTSREGTSLNSSNSSLLLMNGPSSLFASESFLGLSTPARNEFGNIFTSAVTKPPSSVTPRHPLEGTHELRQACQICFVKSGPKLMDFTYLANIDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAAEEECRYSGHCTFAYCQEEIDVWTLERKGAFSREAFFGGNGKIHLTVFKLLQEHLGEFIFLCEKCFDHKPRMISKRNKDNSTSCSHPVTKHEFEDNKCLVHILRETTVKYSKIRSFHGQCQLDLCRHEVRYGCLREDECFYAHSLVELKVWMLQSETGISHDAIAEESKRYWQNLEANVPGAQVLGDQIMPGSLNMKIKFVCAQCLRNGQVIEPDKNRKYCSAKARHSWTKDRRAMRVMSIERKKWMNIRPLPTKKQMPLQFDLCNHIASGKKCQYVGNCSFAHSPEERDVWTYMKENGIQDMEQFYELWLKSQKNEKSDDVASQSNKDNGKQIHMPTDYAEVTVDFHCWMCRKNCNSEKQWQGHISSEKHKEKVFYTESDQYCWQHRFPTGYFSICDRYINGTCTEGSSCKFAHGNAELQEWEERRDALKMKLNKARKDHLIAPNDNDFGKYSFLFKDLN", "length": 971 }, "evidence": [ { "id": "A0A8V0ZLR8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLR8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZP12-1", "protein_name": "Zinc finger CCCH type containing 7 A", "gene_name": "Zc3h7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSVSEERRKRQHSIKDGLQFIQSPLSYPGTQEQYAVYLHALVRNLFNEGNDVYRECDWSGSLLQYSEALNIASYAKSEEILIPKEIIEKLQINRIACYSNMGLHDKVLEDCNAVLSVNASNCKALYRKAKALSDLRRYREAYDVVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAELSLKAVPGDGAPKAVNHSVEDIEPDLLTPRQEALSVVSLPTSSFSHVIGSELASVPIMPVTSVLQLQVDESPLPSTVFANGGKIPFTISEAFLDDDIVLGDEIDALLDSAPETNDAVMSSTLVRGPLPTASAAPGFPFRAPSLLGTLPIGARYAPEPSFAECFPPLTSPLEDFYSSLNAFSVTESTRDLSTSTAREGTALNSSNSSLLLMNGPGSLFASDNFLGITSQPSNDCGNLFGSVIAKPFSSGTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANLDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAADDECRYSGHCTFAYCQEEIDVWTLERTGAFSREAFFGGNGKISLTVVKILQEHLGEFTFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILREATVKYSKIRSFHKQCQLDLCRHEVRYGCVREDECFYAHSLIELKVWIMQNERGISHDDIAQQSRQYWRSLEASLPGLQVLGNQIMPGLLNMEIKFVCAQCLRNGQVTEPDRNRKYCSAKAQHSWTKERRAMRAMSFERKKWMNIRPLPTKKQMPLQFDLCNHIANRKKCQYVGNCSFAHSPEEREVWTYMKDNKIHDIEQFYELWLKNQKTEKSDETSSHCSKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQDHISSEKHKEKVFHTEDDQYCWQHRFPTGYFSVCDRYMDGSCTEGSSCKFAHGNAELHEWEERRKALQMKLQKARKDHLIAPNDNDFGKYSFLFKDLK", "length": 971 }, "evidence": [ { "id": "A0A8V0ZLR8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLR8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PWW6-1", "protein_name": "Zinc finger CCCH type containing 7 A", "gene_name": "Zc3h7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSVSEERRKRQHSIKEGLQFIQSPLSYPGTQEQYAVYLHALVRNLFNEGNDIYRECDWRGSLIQYSEALSIANYAKSEEILIPTEIIEKLRINRIACYSNMGLRDEVLEDCNAVLSVNASNCKALYRKAKALSDLGHYREAYDAVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAEHLLKAVPGDGAPKAVNYSVEDIEPDLLAPRQEALSVASLPTSSFSHVIGSELASVPIMPVTSVLQLQVDESPLPSTVFANGGKIPFTISDAFLDDDIVLGDEIDALLDSAPETNDAVMSSTLVRGPLPTASAAPSLPFRTQSLLGTLPMGTRYPEPSFADFFPPLTSSLEEFYSSLNSFSVTESKRDLCTSTAREGTPLNNSNSSLLLMNGPGNLLASENFLGITSQPRNDFGNFFGSVIAKPFSSGTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANVDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAADDECRYPGHCTFAYCQEEIDVWTLERKGAFSREAFFGGNGKINLTVVRILQEHHGEFTFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILRETTVKYSKIRSFHKQCQFDICRHEVRYGCVREDECFYAHSLIELKVWIMQSERGISHDDIAQQSKQYWRSLQASMPGVQVLGNQIMPGLLNMEIKFVCAQCLRNGQVIEPDRNRKYCSAKAQHSWTKERRAMRAMSFERKKWMNIRPLPTKKQMPLQFDLCNHIANRKKCQYVGNCSFAHSPEEREVWTYMKDNKIHDIEQFYELWLKNQKTEKSDETASHCSKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQDHISSEKHKEKVFHTEDDQYCWQHRFPTGYFSICERYINGSCTEGSSCKFAHGNAELHEWEERRKALQMKFKKARKDHLIAPNDNDFGKYSFLFKDLK", "length": 970 }, "evidence": [ { "id": "A0A8V0ZLR8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLR8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWR0-1", "protein_name": "Zinc finger CCCH domain-containing protein 7A", "gene_name": "ZC3H7A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNVSEERRKRQQNIKEGLQFIQSPLSYPGTQEQYAVYLRALVRNLFNEGNDVYREHDWNNSISQYTEALNIADYAKSEEILIPKEIIEKLYINRIACYSNMGFHDKVLEDCNIVLSLNASNCKALYRKSKALSDLGRYKKAYDAVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAELSLKSVPGDGATKALNHSVEDIEPDLLTPRQEAVPVVSLPAPSFSHEVGSELASVPVMPLTSILPLQVEESALPSAVLANGGKMPFTMPEAFLDDGDMVLGDELDDLLDSAPETNETVMPSALVRGPLQTASVSPSMPFSASLLGTLPIGARYAPPPSFSEFYPPLTSSLEDFCSSLNSFSMSESKRDLSTSTSREGTPLNNSNSSLLLMNGPGSLFASENFLGISSQPRNDFGNFFGSAVTKPSSSVTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANIDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAAEEECRYSGHCTFAYCQEEIDVWTLERKGAFSREAFFGGNGKINLTVFKLLQEHLGEFIFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILRETTVKYSKIRSFHGQCQLDLCRHEVRYGCLREDECFYAHSLVELKVWIMQNETGISHDAIAQESKRYWQNLEANVPGAQVLGNQIMPGFLNMKIKFVCAQCLRNGQVIEPDKNRKYCSAKARHSWTKDRRAMRVMSIERKKWMNIRPLPTKKQMPLQFDLCNHIASGKKCQYVGNCSFAHSPEEREVWTYMKENGIQDMEQFYELWLKSQKNEKSEDIASQSNKENGKQIHMPTDYAEVTVDFHCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQYCWQHRFPTGYFSICDRYMNGTCPEGNSCKFAHGNAELHEWEERRDALKMKLNKARKDHLIGPNDNDFGKYSFLFKDLN", "length": 971 }, "evidence": [ { "id": "A0A8V0ZLR8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLR8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8" } ], "pmid": "" }, { "name": "miRNA binding", "id": "GO:0035198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "post-transcriptional regulation of gene expression", "id": "GO:0010608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8" } ], "pmid": "" }, { "name": "miRNA processing", "id": "GO:0035196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035196", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR8" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 634, "end_pos": 656, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 591, "end_pos": 593 }, { "start_pos": 789, "end_pos": 791 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLT2-1", "uniprot_ac": "A0A8V0ZLT2", "uniprot_id": "A0A8V0ZLT2_CHICK", "mass": { "chemical_mass": 74518.0, "monoisotopic_mass": 74518.0 }, "refseq": {}, "gene_names": [ { "name": "RPH3A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ] } ], "protein_names": [ { "name": "Rabphilin-3A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2/entry#names_and_taxonomy" } ] }, { "name": "Exophilin-1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays an essential role in docking and fusion steps of regulated exocytosis. At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP-dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release. In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability. Also plays a role in the exocytosis of arginine vasopressin hormone.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z8L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8L2#function" }, { "database": "UniProtKB", "id": "ARBA00060345", "url": "https://www.uniprot.org/uniprotkb/ARBA00060345#function" }, { "database": "UniProtKB", "id": "A0A8V0ZED6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZED6#function" }, { "database": "UniProtKB", "id": "A0A8V0ZFH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPH3A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2", "locus": { "chromosome": "15", "start_pos": 6466345, "end_pos": 6426670, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020719", "url": "https://www.ensembl.org/id/ENSGALG00010020719" } ] } } ], "crossref": [ { "id": "A0A8V0ZLT2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLT2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04035", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04035", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15762", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15762", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416886", "url": "https://www.ncbi.nlm.nih.gov/gene/416886", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z8L2", "url": "https://www.orthodb.org/?gene=A0A8V0Z8L2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZED6", "url": "https://www.orthodb.org/?gene=A0A8V0ZED6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFH8", "url": "https://www.orthodb.org/?gene=A0A8V0ZFH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLT2", "url": "https://www.orthodb.org/?gene=A0A8V0ZLT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLT7", "url": "https://www.orthodb.org/?gene=A0A8V0ZLT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45729", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45729", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45729:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45729:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02318", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02318", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z8L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z8L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8L2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZED6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZED6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZED6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZED6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFH8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTSASSQEESMENRGGLHDFSPSRGNVVPGCPPPSPCRIPAGWAARGGQPERQRKGEELTDEEKEIINRVIARAEKMEEMEQERIGRLMTRLEDMRRSVLGDGVNRCILCGEQLGPRGSACVVCEDCKKNVCTKCGVETTNSRPHPIWLCKICSEQREVWKRSGAWFFKGLPKQMLPQPMPVSKSKVPPAPSEPSPAEPPAPDPKVPSRTPGRGQADEQDHCGSEVTMAARVRKPAEGRTGPCGSEDTESREPTTESGVSRSPGVKRANSMQSNSTPPPRPPAVTAGPAAPAAARPGPGAAGRMLETQASPPPGPPEPARAAPKEERAGGYAAPPARDERPARPPGAPQPPAPLRQPPPEEEEEDANSYDSDEGTTLGALEFSLLYDQENSALHCTLIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLVYHGITDEDMTRKTLRISVCDEDKFGHNEFIGETRVSLKKLKANQKKNFNICLERVIPMKRAGTTGSSRGMALYEEEVDRGGDVEERGKILVSLMYSTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGITAKGERLKHWYECLKNKDKKIERWHTLQNENHVASD", "length": 678, "header": "tr|A0A8V0ZLT2-1|A0A8V0ZLT2_CHICK Isoform 1 of Rabphilin-3A OS=Gallus gallus OX=9031 GN=RPH3A PE=4 SV=1 CANONICAL=A0A8V0ZLT2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z8L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2/entry#A0A8V0Z8L2-1", "sequence": { "sequence": "MTDAVVGGSADRWMCPGDRTMSLRARIPAGWAARGGQPERQRKGEELTDEEKEIINRVIARAEKMEEMEQERIGRLMTRLEDMRRSVLGDGVNRCILCGEQLGPRGSACVVCEDCKKNVCTKCGVETTNSRPHPIWLCKICSEQREVWKRSGAWFFKGLPKQMLPQPMPVSKSKVPPAPSEPSPAEPPAPDPKVPSRTPGRGSEVTMAARVRKPAEGRTGPCGSEDTESREPTTESGVSRSPGVKRANSMQSNSTPPPRPPAVTAGPAAPAAARPGPGAAGRMLETQASPPPGPPEPARAAPKEERAGGYAAPPARDERPARPPGAPQPPAPLRQPPPEEEEEDANSYDSDEGTTLGALEFSLLYDQENSALHCTLIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLVYHGITDEDMTRKTLRISVCDEDKFGHNEFIGETRVSLKKLKANQKKNFNICLERVIPMKRAGTTGSSRGMALYEEEVDRGGDVEERGKILVSLMYSTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGITAKGERLKHWYECLKNKDKKIERWHTLQNENHVASD", "length": 656, "header": "tr|A0A8V0Z8L2-1|A0A8V0ZLT2_CHICK Computationally mapped isoform of Rabphilin-3A OS=Gallus gallus OX=9031 GN=RPH3A PE=4 SV=1 CANONICAL=A0A8V0ZLT2-1" }, "locus": { "chromosome": "15", "start_pos": 6464395, "end_pos": 6450413, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050084.1", "url": "https://www.ensembl.org/id/ENSGALT00010050084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029595.1", "url": "https://www.ensembl.org/id/ENSGALP00010029595.1" } ] } }, { "isoform_ac": "A0A8V0ZED6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2/entry#A0A8V0ZED6-1", "sequence": { "sequence": "MGTSASSQEESMENRGGLHDFSPSRGNVVPGCPPPSPCRIPAGWAARGGQPERQRKGEELTDEEKEIINRVIARAEKMEEMEQERIGRLMTRLEDMRRSVLGDGVNRCILCGEQLGPRGSACVVCEDCKKNVCTKCGVETTNSRPHPIWLCKICSEQREVWKRSGAWFFKGLPKQMLPQPMPVSKSKVPPAPSEPSPAEPPAPDPKVPSRTPGRGSEVTMAARVRKPAEGRTGPCGSEDTESREPTTESGVSRSPGVKRANSMQSNSTPPPRPPAVTAGPAAPAAARPGPGAAGRMLETQASPPPGPPEPARAAPKEERAGGYAAPPARDERPARPPGAPQPPAPLRQPPPEEEEEDANSYDSDEGTTLGALEFSLLYDQENSALHCTLIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLVYHGITDEDMTRKTLRISVCDEDKFGHNEFIGETRVSLKKLKANQKKNFNICLERVIPMKRAGTTGSSRGMALYEEEVDRGGDVEERGKILVSLMYSTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGITAKGERLKHWYECLKNKDKKIERWHTLQNENHVASD", "length": 669, "header": "tr|A0A8V0ZED6-1|A0A8V0ZLT2_CHICK Computationally mapped isoform of Rabphilin-3A OS=Gallus gallus OX=9031 GN=RPH3A PE=4 SV=1 CANONICAL=A0A8V0ZLT2-1" }, "locus": { "chromosome": "15", "start_pos": 6464395, "end_pos": 6451966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050070.1", "url": "https://www.ensembl.org/id/ENSGALT00010050070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029587.1", "url": "https://www.ensembl.org/id/ENSGALP00010029587.1" } ] } }, { "isoform_ac": "A0A8V0ZFH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2/entry#A0A8V0ZFH8-1", "sequence": { "sequence": "MTDAVVGGSADRWMCPGDRTMSLRASSEKEQIPAGWAARGGQPERQRKGEELTDEEKEIINRVIARAEKMEEMEQERIGRLMTRLEDMRRSVLGDGVNRCILCGEQLGPRGSACVVCEDCKKNVCTKCGVETTNSRPHPIWLCKICSEQREVWKRSGAWFFKGLPKQMLPQPMPVSKSKVPPAPSEPSPAEPPAPDPKVPSRTPGRGQADEQDHCGSEVTMAARVRKPAEGRTGPCGSEDTESREPTTESGVSRSPGVKRANSMQSNSTPPPRPPAVTAGPAAPAAARPGPGAAGRMLETQASPPPGPPEPARAAPKEERAGGYAAPPARDERPARPPGAPQPPAPLRQPPPEEEEEDANSYDSDEGTTLGALEFSLLYDQENSALHCTLIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLVYHGITDEDMTRKTLRISVCDEDKFGHNEFIGETRVSLKKLKANQKKNFNICLERVIPMKRAGTTGSSRGMALYEEEVDRGGDVEERGKILVSLMYSTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGITAKGERLKHWYECLKNKDKKIERWHTLQNENHVASD", "length": 670, "header": "tr|A0A8V0ZFH8-1|A0A8V0ZLT2_CHICK Computationally mapped isoform of Rabphilin-3A OS=Gallus gallus OX=9031 GN=RPH3A PE=4 SV=1 CANONICAL=A0A8V0ZLT2-1" }, "locus": { "chromosome": "15", "start_pos": 6464395, "end_pos": 6450413, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050075.1", "url": "https://www.ensembl.org/id/ENSGALT00010050075.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029589.1", "url": "https://www.ensembl.org/id/ENSGALP00010029589.1" } ] } }, { "isoform_ac": "A0A8V0ZLT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2/entry#A0A8V0ZLT2-1", "sequence": { "sequence": "MGTSASSQEESMENRGGLHDFSPSRGNVVPGCPPPSPCRIPAGWAARGGQPERQRKGEELTDEEKEIINRVIARAEKMEEMEQERIGRLMTRLEDMRRSVLGDGVNRCILCGEQLGPRGSACVVCEDCKKNVCTKCGVETTNSRPHPIWLCKICSEQREVWKRSGAWFFKGLPKQMLPQPMPVSKSKVPPAPSEPSPAEPPAPDPKVPSRTPGRGQADEQDHCGSEVTMAARVRKPAEGRTGPCGSEDTESREPTTESGVSRSPGVKRANSMQSNSTPPPRPPAVTAGPAAPAAARPGPGAAGRMLETQASPPPGPPEPARAAPKEERAGGYAAPPARDERPARPPGAPQPPAPLRQPPPEEEEEDANSYDSDEGTTLGALEFSLLYDQENSALHCTLIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLVYHGITDEDMTRKTLRISVCDEDKFGHNEFIGETRVSLKKLKANQKKNFNICLERVIPMKRAGTTGSSRGMALYEEEVDRGGDVEERGKILVSLMYSTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGITAKGERLKHWYECLKNKDKKIERWHTLQNENHVASD", "length": 678, "header": "tr|A0A8V0ZLT2-1|A0A8V0ZLT2_CHICK Isoform 1 of Rabphilin-3A OS=Gallus gallus OX=9031 GN=RPH3A PE=4 SV=1 CANONICAL=A0A8V0ZLT2-1" }, "locus": { "chromosome": "15", "start_pos": 6464395, "end_pos": 6451966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050069.1", "url": "https://www.ensembl.org/id/ENSGALT00010050069.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029586.1", "url": "https://www.ensembl.org/id/ENSGALP00010029586.1" } ] } }, { "isoform_ac": "A0A8V0ZLT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2/entry#A0A8V0ZLT7-1", "sequence": { "sequence": "MEDGNNVVPSAMTDAVVGGSADRWMCPGDRTMSLRASSEKEQIPAGWAARGGQPERQRKGEELTDEEKEIINRVIARAEKMEEMEQERIGRLMTRLEDMRRSVLGDGVNRCILCGEQLGPRGSACVVCEDCKKNVCTKCGVETTNSRPHPIWLCKICSEQREVWKRSGAWFFKGLPKQMLPQPMPVSKSKVPPAPSEPSPAEPPAPDPKVPSRTPGRGSEVTMAARVRKPAEGRTGPCGSEDTESREPTTESGVSRSPGVKRANSMQSNSTPPPRPPAVTAGPAAPAAARPGPGAAGRMLETQASPPPGPPEPARAAPKEERAGGYAAPPARDERPARPPGAPQPPAPLRQPPPEEEEEDANSYDSDEGTTLGALEFSLLYDQENSALHCTLIRAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPVWNETLVYHGITDEDMTRKTLRISVCDEDKFGHNEFIGETRVSLKKLKANQKKNFNICLERVIPMKRAGTTGSSRGMALYEEEVDRGGDVEERGKILVSLMYSTQQGGLIVGIVRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGITAKGERLKHWYECLKNKDKKIERWHTLQNENHVASD", "length": 672, "header": "tr|A0A8V0ZLT7-1|A0A8V0ZLT7_CHICK Computationally mapped isoform of Rabphilin-3A OS=Gallus gallus OX=9031 GN=RPH3A PE=4 SV=1 CANONICAL=A0A8V0ZLT2-1" }, "locus": { "chromosome": "15", "start_pos": 6464395, "end_pos": 6443819, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050079.1", "url": "https://www.ensembl.org/id/ENSGALT00010050079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029591.1", "url": "https://www.ensembl.org/id/ENSGALP00010029591.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 286, "start_aa": "Thr", "end_pos": 286, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr286", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" }, { "name": "positive regulation of calcium ion-dependent exocytosis", "id": "GO:0045956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" }, { "name": "synaptic vesicle priming", "id": "GO:0016082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" }, { "name": "calcium-dependent activation of synaptic vesicle fusion", "id": "GO:0099502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" }, { "name": "extrinsic component of synaptic vesicle membrane", "id": "GO:0098850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098850", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLT2" }, { "id": "PS50004", "database": "PROSITE", "url": 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"Gln", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 286 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 275, "end_pos": 277 }, { "start_pos": 445, "end_pos": 447 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMW2-1", "uniprot_ac": "A0A8V0ZMW2", "uniprot_id": "A0A8V0ZMW2_CHICK", "mass": { "chemical_mass": 75199.0, "monoisotopic_mass": 75199.0 }, "refseq": { "ac": "NP_001385039", "name": "RNA polymerase-associated protein LEO1 isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385039" }, "gene_names": [ { "name": "LEO1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2" } ] }, { "name": "LEO1", "type": "synonym", "evidence": [ { "id": "NP_001385039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385039" } ] } ], "protein_names": [ { "name": "RNA polymerase-associated protein LEO1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2/entry#names_and_taxonomy" } ] }, { "name": "Leo1, Paf1/RNA polymerase II complex component, homolog", "type": "synonym", "evidence": [ { "id": "NP_001385039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385039" } ] }, { "name": "RNA polymerase-associated protein LEO1 isoform 2", "type": "synonym", "evidence": [ { "id": "NP_001385039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385039" } ] }, { "name": "RNA polymerase-associated protein LEO1-like", "type": "synonym", "evidence": [ { "id": "NP_001385039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385039" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.259515.1, SRR13267655.231879.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On Dec 8, 2021 this sequence version replaced XP_040562345.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001385039", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385039" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LEO1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2", "locus": { "chromosome": "10", "start_pos": 9019755, "end_pos": 9031396, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021010", "url": "https://www.ensembl.org/id/ENSGALG00010021010" } ] } } ], "crossref": [ { "id": "A0A8V0ZMW2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "769405", "url": "https://www.ncbi.nlm.nih.gov/gene/769405", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RSDRSMH", "url": "https://omabrowser.org/oma/group/RSDRSMH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9P6", "url": "https://www.orthodb.org/?gene=A0A8V0Z9P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Q3", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9R4", "url": "https://www.orthodb.org/?gene=A0A8V0Z9R4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMW2", "url": "https://www.orthodb.org/?gene=A0A8V0ZMW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMW7", "url": "https://www.orthodb.org/?gene=A0A8V0ZMW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23146", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23146", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23146:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23146:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-201722", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001385039", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385039", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9R4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADMEELFGSDADSEAEQKDTDSGSDSDSDQENAGSGSNASGSDSEQDDEREAAKPSNKELFGDDSEDEGASHHTGSDNHSERSYNRSEASGHSEHEDNDQSDVDQHSASEAAHDDEEDERGHGSDEGSHHSEGDGSEKAHSEDEKWGKEDKSDQSDDEERQQNSDDEERQQNSDDEEKAQNSDEDERPQMSDDEERLQNSDEEKMQNSDDEERPQVSDEEKMQNSDDDERAQHSDEEKMQNSDDDERAQRSDEEEQEHKSGESARGSDSEDEVLRMKRKKPIASDSEADSDTEGQKGKAGIEHADVMDLFGGADDISSGSDGEDKPPTPGQPIDENGLSQEQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRMRRDEEGNEIRESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPESQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSANYLEPDRYEEEDEGDDAISLAAIKNRYKGGIREERARIYSSDSDEGSDEDKTQRLLKAKKLTSDEEGEPSGKRKAEDDDKASKKHKKYVISDEEEDDDD", "length": 662, "header": "tr|A0A8V0ZMW2-1|A0A8V0ZMW2_CHICK Isoform 1 of RNA polymerase-associated protein LEO1 OS=Gallus gallus OX=9031 GN=LEO1 PE=1 SV=1 CANONICAL=A0A8V0ZMW2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z9P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2/entry#A0A8V0Z9P6-1", "sequence": { "sequence": "MADMEELFGSDADSEAEQKDTDSGSDSDSDQENAGSGSNASGSDSEQDDEREAAKPSNKELFGDDSEDEGASHHTGSDNHSERSYNRSEASGHSEHEDNDQSDVDQHSASEAAHDDEEDERGHGSDEGSHHSEGDGSEKAHSEDEKWGKEDKSDQSDDEERQQNSDDEERQQNSDDEEKAQNSDEDERPQMSDDEERLQNSDEEKMQNSDDEERPQVSDEEKMQNSDDDERAQHSDEEKMQNSDDDERAQRSDEEEQEHKSGESARGSDSEDEVLRMKRKKPIASDSEADSDTEGQKEHADVMDLFGGADDISSGSDGEDKPPTPGQPIDENGLSQEQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRMRRDEEGNEIRESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPESQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSANYLEPDRYEEEDEGDDAISLAAIKNRYKGGIREERARIYSSDSDEGSDEDKTQRLLKAKKLTSDEQVTVNVINEDILHIGR", "length": 639, "header": "tr|A0A8V0Z9P6-1|A0A8V0ZMW2_CHICK Computationally mapped isoform of RNA polymerase-associated protein LEO1 OS=Gallus gallus OX=9031 GN=LEO1 PE=1 SV=1 CANONICAL=A0A8V0ZMW2-1" }, "locus": { "chromosome": "10", "start_pos": 9031344, "end_pos": 9024064, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050806.1", "url": "https://www.ensembl.org/id/ENSGALT00010050806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029997.1", "url": "https://www.ensembl.org/id/ENSGALP00010029997.1" } ] } }, { "isoform_ac": "A0A8V0Z9Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2/entry#A0A8V0Z9Q3-1", "sequence": { "sequence": "MADMEELFGSDADSEAEQKDTDSGSDSDSDQENAGSGSNASGSDSEQDDEREAAKPSNKELFGDDSEDEGASHHTGSDNHSERSYNRSEASGHSEHEDNDQSDVDQHSASEAAHDDEEDERGHGSDEGSHHSEGDGSEKAHSEDEKWGKEDKSDQSDDEERQQNSDDEERQQNSDDEEKAQNSDEDERPQMSDDEERLQNSDEEKMQNSDDEERPQVSDEEKMQNSDDDERAQHSDEEKMQNSDDDERAQRSDEEEQEHKSGESARGSDSEDEVLRMKRKKPIASDSEADSDTEGQKEHADVMDLFGGADDISSGSDGEDKPPTPGQPIDENGLSQEQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRMRRDEEGNEIRESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPESQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSANYLEPDRYEEEDEGDDAISLAAIKNRYKGGIREERARIYSSDSDEGSDEDKTQRLLKAKKLTSDEFTDLSDT", "length": 630, "header": "tr|A0A8V0Z9Q3-1|A0A8V0ZMW2_CHICK Computationally mapped isoform of RNA polymerase-associated protein LEO1 OS=Gallus gallus OX=9031 GN=LEO1 PE=1 SV=1 CANONICAL=A0A8V0ZMW2-1" }, "locus": { "chromosome": "10", "start_pos": 9031344, "end_pos": 9024926, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050811.1", "url": "https://www.ensembl.org/id/ENSGALT00010050811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030002.1", "url": "https://www.ensembl.org/id/ENSGALP00010030002.1" } ] } }, { "isoform_ac": "A0A8V0Z9R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2/entry#A0A8V0Z9R4-1", "sequence": { "sequence": "MADMEELFGSDADSEAEQKDTDSGSDSDSDQENAGSGSNASGSDSEQDDEREAAKPSNKELFGDDSEDEGASHHTGSDNHSERSYNRSEASGHSEHEDNDQSDVDQHSASEAAHDDEEDERGHGSDEGSHHSEGDGSEKAHSEDEKWGKEDKSDQSDDEERQQNSDDEERQQNSDDEEKAQNSDEDERPQMSDDEERLQNSDEEKMQNSDDEERPQVSDEEKMQNSDDDERAQHSDEEKMQNSDDDERAQRSDEEEQEHKSGESARGSDSEDEVLRMKRKKPIASDSEADSDTEGQKEHADVMDLFGGADDISSGSDGEDKPPTPGQPIDENGLSQEQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRMRRDEEGNEIRESNARIVKWSDGRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPESQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSANYLEPDRYEEEDEGDDAISLAAIKNRYKGGIREERARIYSSDSDEGSDEDKTQRLLKAKKLTSDEEGEPSGKRKAEDDDKASKKHKKYVISDEEEDDDD", "length": 612, "header": "tr|A0A8V0Z9R4-1|A0A8V0ZMW2_CHICK Computationally mapped isoform of RNA polymerase-associated protein LEO1 OS=Gallus gallus OX=9031 GN=LEO1 PE=1 SV=1 CANONICAL=A0A8V0ZMW2-1" }, "locus": { "chromosome": "10", "start_pos": 9031344, "end_pos": 9021940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050826.1", "url": "https://www.ensembl.org/id/ENSGALT00010050826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030017.1", "url": "https://www.ensembl.org/id/ENSGALP00010030017.1" } ] } }, { "isoform_ac": "A0A8V0ZMW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2/entry#A0A8V0ZMW2-1", "sequence": { "sequence": "MADMEELFGSDADSEAEQKDTDSGSDSDSDQENAGSGSNASGSDSEQDDEREAAKPSNKELFGDDSEDEGASHHTGSDNHSERSYNRSEASGHSEHEDNDQSDVDQHSASEAAHDDEEDERGHGSDEGSHHSEGDGSEKAHSEDEKWGKEDKSDQSDDEERQQNSDDEERQQNSDDEEKAQNSDEDERPQMSDDEERLQNSDEEKMQNSDDEERPQVSDEEKMQNSDDDERAQHSDEEKMQNSDDDERAQRSDEEEQEHKSGESARGSDSEDEVLRMKRKKPIASDSEADSDTEGQKGKAGIEHADVMDLFGGADDISSGSDGEDKPPTPGQPIDENGLSQEQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRMRRDEEGNEIRESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPESQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSANYLEPDRYEEEDEGDDAISLAAIKNRYKGGIREERARIYSSDSDEGSDEDKTQRLLKAKKLTSDEEGEPSGKRKAEDDDKASKKHKKYVISDEEEDDDD", "length": 662, "header": "tr|A0A8V0ZMW2-1|A0A8V0ZMW2_CHICK Isoform 1 of RNA polymerase-associated protein LEO1 OS=Gallus gallus OX=9031 GN=LEO1 PE=1 SV=1 CANONICAL=A0A8V0ZMW2-1" }, "locus": { "chromosome": "10", "start_pos": 9031344, "end_pos": 9021940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050817.1", "url": "https://www.ensembl.org/id/ENSGALT00010050817.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030008.1", "url": "https://www.ensembl.org/id/ENSGALP00010030008.1" } ] } }, { "isoform_ac": "A0A8V0ZMW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2/entry#A0A8V0ZMW7-1", "sequence": { "sequence": "MADMEELFGSDADSEAEQKDTDSGSDSDSDQENAGSGSNASGSDSEQDDEREAAKPSNKELFGDDSEDEGASHHTGSDNHSERSYNRSEASGHSEHEDNDQSDVDQHSASEAAHDDEEDERGHGSDEGSHHSEGDGSEKAHSEDEKWGKEDKSDQSDDEERQQNSDDEERQQNSDDEEKAQNSDEDERPQMSDDEERPQVSDEEKMQNSDDDERAQHSDEEKMQNSDDDERAQRSDEEEQEHKSGESARGSDSEDEVLRMKRKKPIASDSEADSDTEGQKEHADVMDLFGGADDISSGSDGEDKPPTPGQPIDENGLSQEQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRMRRDEEGNEIRESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPESQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSANYLEPDRYEEEDEGDDAISLAAIKNRYKGGIREERARIYSSDSDEGSDEDKTQRLLKAKKLTSDEEGEPSGKRKAEDDDKASKKHKKYVISDEEEDDDD", "length": 640, "header": "tr|A0A8V0ZMW7-1|A0A8V0ZMW7_CHICK Computationally mapped isoform of RNA polymerase-associated protein LEO1 OS=Gallus gallus OX=9031 GN=LEO1 PE=1 SV=1 CANONICAL=A0A8V0ZMW2-1" }, "locus": { "chromosome": "10", "start_pos": 9031344, "end_pos": 9021940, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050822.1", "url": "https://www.ensembl.org/id/ENSGALT00010050822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030013.1", "url": "https://www.ensembl.org/id/ENSGALP00010030013.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 329, "start_aa": "Thr", "end_pos": 329, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr329", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-201722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201722", "resource": "Reactome", "description": "Formation of the beta-catenin:TCF transactivating complex" }, { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RZB7-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "LEO1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADMEDLFGSDVDSDAERKDSDSGSESDSDQENVASGSNASGSESDQDERDDSGKPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEVSERSDHEDNDPSDVDQHSGSEAHNDDEDEGHRSDGGSHHSEVEGSEKAHSDDEKWGGEDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDEQPAASDNDDEKQNSDDEERPQMSDEEKMQNSDDERPQGSDEEHRHSEDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESISLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGKRKAEDDDKANKKHKKYVISDEEEEDDD", "length": 666 }, "evidence": [ { "id": "A0A8V0ZMW2", "url": "https://omabrowser.org/oma/group/A0A8V0ZMW2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P38439-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "LEO1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSESPQDQPQKEQISNNVGVTTNSTSNEETSRSQDDNVKEVNGNDDTKEEEQEEDAELDDLFGDDNDDDDDDDVKKSETEKSDSDSDEDDEGENINHRSRHRESLGLDDDEAEEQAMYTRKFYGEDANNFSDQDETTHTFKEENVELVRHIIPSKANVNETASHNEIFYARIPNFLTIDPIPFDPPSFEAKVNERASNSASREDQLDDRLIDENTVRWRYSRDKDQHVFKESNTQIVQWSDGTYSLKVGEECTDILVNDTSNTFLTVSHDQQELIQCYEGGEIKKTLMFIPTSTNSKIHQKLSKAVIRRNQRQSKGPGTYIVSMDPEVEKKELERKQSQILRDRRRRQLKEKEKQESPDAAFETGFRKQNSPTTYGASRRNEYEEDDFLVDDDEEEEAAFDDEEDDNEEEEEEEDADEENASRLRNLKREGAAMYREEEEEEKDRSETKRRRVAVIEDDEDED", "length": 464 }, "evidence": [ { "id": "A0A8V0ZMW2", "url": "https://omabrowser.org/oma/group/A0A8V0ZMW2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5XJE5-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "Leo1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADMEDLFGSEAESEAERKDSESESDSDSDQDNGASGSNASGSESDQDDRGDSGQPSNKELFGDDSEEEGASHHSGSDNHSERSDNRSEASERSDHEDNEPSDEDQHSGSEAHNDDDDEGHRSDEGSRHSEAEGSEKAQSDDEKWDGEDKSDQSDDEKLQNSDDEDREQGSDEDKLQNSDDDEEKMQNTDDEDRAQISDDDRQQLSEEEKGNSDDEHPVASDNDEEKQNSDDEDQPQVSDEEKMQNSDDERPQVSDEDGRRSDGEEEQDQKSESARGSDSEDEVLRLKRKNAIPSDSEADSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESVSLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLNSDEEGESSGKRKAEDDDKANKKHKKYVISDEEEEEDD", "length": 667 }, "evidence": [ { "id": "A0A8V0ZMW2", "url": "https://omabrowser.org/oma/group/A0A8V0ZMW2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q641X2-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "Leo1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADMEDLFGSEAESEAERKDSDSGSDSDSDQDNGASGSNASGSESDQDERGDSGQPSNKELFGDDSEEEGAPHHSGSDNHSEQSDNRSEASEERSDHEDNEPSDVDQHSGSEAHNDDDDDDDDEDDDDEGHRSDEGSHHSEAEGSEKAQSDDEKWDGEDKSDQSDDDEKLQNSDDEEREQGSDDEKLQNSADEEEKMQNTDDEDRAQLSDDDRQQLSEEEKGNSDDERPAASDNDEEKQNSDDEDRPQVSDEEKMQNSDDERPQVSDEDRRHSDDEEEQDQKSESARGSDSEDEVLRMKRKNAIPSDSEVDSDTEVPKDNNGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRMRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESVSLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLNSDEEGESSGKRKAEDDDKANKKHKKYVISDEEEEEDD", "length": 678 }, "evidence": [ { "id": "A0A8V0ZMW2", "url": "https://omabrowser.org/oma/group/A0A8V0ZMW2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WVC0-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "LEO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADMEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEFEDEEMLDEEGRTRLKLKVENTIRWRIRRDEEGNEIKESNARIVKWSDGSMSLHLGNEVFDVYKAPLQGDHNHLFIRQGTGLQGQAVFKTKLTFRPHSTDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSASYLEPDRYDEEEEGEESISLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGKRKAEDDDKANKKHKKYVISDEEEEDDD", "length": 666 }, "evidence": [ { "id": "A0A8V0ZMW2", "url": "https://omabrowser.org/oma/group/A0A8V0ZMW2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FNQ0-1", "protein_name": "Protein LEO1 homolog", "gene_name": "VIP4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVKGEKRSEMMLNLFGDNSEEEEIESEHECNRRQPNYASDEAEGGVEPEGEGEAEVEVHGEAEAESDGEQGDVELDPGESEGEREQSSQEADPQEESEARDSDSDNKEEEHGGRVAKKRRQEVVESGSERSGEKHYESEDEEVDQTRSPRSPSEEKEEVQVAQSDVNIRNVFGSSDDEDAEEYVRNDVEQDEHRSPIEDEEGSEKDLRPDDMVLDDIIPEEDPQYESEAEHVEARYRERPVGPPLEVEVPFRPPPGDPVKMNMIKVSNIMGIDPKPFDAKTFVEEDTFMTDEPGAKNRIRLDNNIVRHRFVKSRDGKTYSESNARFVRWSDGSLQLLIGNEVLNITEQDAKEDQNHLFIKHEKGILQSQGRILKKMRFTPSSLTSNSHRLLTAIVESRQKKAFKVKNCVTDIDPEREKEKREKAESQNLKASTKLSQAREKIKRKYPLPVERRQLSTGYLEDALDEDDEDYRSNRGYEEDLEAEAQRERRILNAKKSHKGIPGRSSMTSARPSRRQMEYSESEREESEYETEEEEEEKSPARGRGKDSEDEYEEDAEEDEEERGKSNRYSDEDEEEEEVAGGRAEKDHRGSGRKRKGIESDEEESPPRKAPTHRRKAVIDDSDED", "length": 625 }, "evidence": [ { "id": "A0A8V0ZMW2", "url": "https://omabrowser.org/oma/group/A0A8V0ZMW2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2" } ], "pmid": "" }, { "name": "negative regulation of myeloid cell differentiation", "id": "GO:0045638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045638", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2" } ], "pmid": "" }, { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Cdc73/Paf1 complex", "id": "GO:0016593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA polymerase II C-terminal domain phosphoserine binding", "id": "GO:1990269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990269", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 329 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 39, "end_pos": 41 }, { "start_pos": 79, "end_pos": 81 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZIZ7-1", "uniprot_ac": "A0A8V0ZIZ7", "uniprot_id": "A0A8V0ZIZ7_CHICK", "mass": { "chemical_mass": 66440.0, "monoisotopic_mass": 66440.0 }, "refseq": { "ac": "XP_040545317", "name": "R3H and coiled-coil domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545317" }, "gene_names": [ { "name": "R3HCC1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZIZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ7" } ] }, { "name": "R3HCC1", "type": "synonym", "evidence": [ { "id": "XP_040545317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545317" } ] } ], "protein_names": [ { "name": "R3H and coiled-coil domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_040545317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545317" } ] }, { "name": "R3H domain and coiled-coil containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZIZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052594.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_040545317.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040545317", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545317" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "R3HCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ7", "locus": { "chromosome": "22", "start_pos": 1296062, "end_pos": 1305233, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020055", "url": "https://www.ensembl.org/id/ENSGALG00010020055" } ] } } ], "crossref": [ { "id": "A0A8V0ZIZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZIZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02638", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02638", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419534", "url": "https://www.ncbi.nlm.nih.gov/gene/419534", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IFPCQAS", "url": "https://omabrowser.org/oma/group/IFPCQAS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBI8", "url": "https://www.orthodb.org/?gene=A0A8V0ZBI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCY6", "url": "https://www.orthodb.org/?gene=A0A8V0ZCY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIZ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZIZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21678:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21678:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040545317", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545317", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBI8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGVFLSPNEDEFVGRIAEELEHFMLQGQHHRVLLFPPLSSRLRYLIHRTVENVDLLSSFSVGEGWRRRTVICHSAVRIPSETSEQNPATTAPRPPRPTQPWGRGARGARLRHGGDGHGDTSRACVGSGRIKRPPRRKPDKALYVPKAMRKKVEWGEQEVGADGAREGEICPKAALEGEAEGGPGPNGAIGGVCLVLDEQHKDGEESGKSSHGTNGDRPPRCTDVPPLESSNSSSGQHSQDKDCSDSLSSVPNENPAEPEEQSKSCDDTVGPEGSKTPCQDQKSRDADSKSSHLLGEHCSDATLVLENPKKSCAMSLESSGNVSVQGEDVVSPVLELGEGPSAPESEDQESFSSAREEPTQQQTPLEARGEAVLAPEPIGGAGPSGRSEQEEHREDVPVAKDGVREPMGLADALQRELRLPKGDQEENAATQSRELAFEDDCTAELLQEIMGHLTVKDISVERITLDYSSYGDAQVHEGDFGHVTEIYDFSPSLKTEHLMEVFSDFHESGFKIQWVDDTHALGIFSSLSAASQALGRRYPSLKIRPLIHATKQSKIKALQRPKLLQLAKERPQTDTVVARRLVTRALGLKHQQQCGSGPEGLLPEGLDQEE", "length": 611, "header": "tr|A0A8V0ZIZ7-1|A0A8V0ZIZ7_CHICK Isoform 1 of R3H domain and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=R3HCC1 PE=1 SV=1 CANONICAL=A0A8V0ZIZ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ7/entry#A0A8V0ZBI8-1", "sequence": { "sequence": "MDGVFLSPNEDEFVGRIAEELEHFMLQGQHHSRLRYLIHRTVENVDLLSSFSVGEGWRRRTVICHSAVRIPSETSEQNPATTAPRPPRPTQPWGRGARGARLRHGGDGHGDTSRACVGSGRIKRPPRRKPDKALYVPKAMRKKVEWGEQEVGADGAREGEICPKAALEGEAEGGPGPNGAIGGVCLVLDEQHKDGEESGKSSHGTNGDRPPRCTDVPPLESSNSSSGQHSQDKDCSDSLSSVPNENPAEPEEQSKSCDDTVGPEGSKTPCQDQKSRDADSKSSHLLGEHCSDATLVLENPKKSCAMSLESSGNVSVQGEDVVSPVLELGEGPSAPESEDQESFSSAREEPTQQQTPLEARGEAVLAPEPIGGAGPSGRSEQEEHREDVPVAKDGVREPMGLADALQRELRLPKGDQEENAATQSRELAFEDDCTAELLQEIMGHLTVKDISVERITLDYSSYGDAQVHEGDFGHVTEIYDFSPSLKTEHLMEVFSDFHESGFKIQWVDDTHALGIFSSLSAASQALGRRYPSLKIRPLIHATKQSKIKALQRPKLLQLAKERPQTDTVVARRLVTRALGLKHQQQCGSGPEGLLPEGLDQEE", "length": 602, "header": "tr|A0A8V0ZBI8-1|A0A8V0ZIZ7_CHICK Computationally mapped isoform of R3H domain and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=R3HCC1 PE=1 SV=1 CANONICAL=A0A8V0ZIZ7-1" }, "locus": { "chromosome": "22", "start_pos": 1304718, "end_pos": 1297527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048457.1", "url": "https://www.ensembl.org/id/ENSGALT00010048457.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028570.1", "url": "https://www.ensembl.org/id/ENSGALP00010028570.1" } ] } }, { "isoform_ac": "A0A8V0ZCY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ7/entry#A0A8V0ZCY6-1", "sequence": { "sequence": "MDGVFLSPNEDEFVGRIAEELEHFMLQGQHHRVLLFPPLSSRLRYLIHRTVENVDLLSSFSVGEGWRRRTVICHSAVRIPSETSEQNPATTAPRPPRPTQPWGRGARGARLRHGGDGHGDTSRACVGSGRIKRPPRRKPDKALYVPKAMRKKVGADGAREGEICPKAALEGEAEGGPGPNGAIGGVCLVLDEQHKDGEESGKSSHGTNGDRPPRCTDVPPLESSNSSSGQHSQDKDCSDSLSSVPNENPAEPEEQSKSCDDTVGPEGSKTPCQDQKSRDADSKSSHLLGEHCSDATLVLENPKKSCAMSLESSGNVSVQGEDVVSPVLELGEGPSAPESEDQESFSSAREEPTQQQTPLEARGEAVLAPEPIGGAGPSGRSEQEEHREDVPVAKDGVREPMGLADALQRELRLPKGDQEENAATQSRELAFEDDCTAELLQEIMGHLTVKDISVERITLDYSSYGDAQVHEGDFGHVTEIYDFSPSLKTEHLMEVFSDFHESGFKIQWVDDTHALGIFSSLSAASQALGRRYPSLKIRPLIHATKQSKIKALQRPKLLQLAKERPQTDTVVARRLVTRALGLKHQQQCGSGPEGLLPEGLDQEE", "length": 604, "header": "tr|A0A8V0ZCY6-1|A0A8V0ZIZ7_CHICK Computationally mapped isoform of R3H domain and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=R3HCC1 PE=1 SV=1 CANONICAL=A0A8V0ZIZ7-1" }, "locus": { "chromosome": "22", "start_pos": 1304718, "end_pos": 1297527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048452.1", "url": "https://www.ensembl.org/id/ENSGALT00010048452.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028566.1", "url": "https://www.ensembl.org/id/ENSGALP00010028566.1" } ] } }, { "isoform_ac": "A0A8V0ZIZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ7/entry#A0A8V0ZIZ7-1", "sequence": { "sequence": "MDGVFLSPNEDEFVGRIAEELEHFMLQGQHHRVLLFPPLSSRLRYLIHRTVENVDLLSSFSVGEGWRRRTVICHSAVRIPSETSEQNPATTAPRPPRPTQPWGRGARGARLRHGGDGHGDTSRACVGSGRIKRPPRRKPDKALYVPKAMRKKVEWGEQEVGADGAREGEICPKAALEGEAEGGPGPNGAIGGVCLVLDEQHKDGEESGKSSHGTNGDRPPRCTDVPPLESSNSSSGQHSQDKDCSDSLSSVPNENPAEPEEQSKSCDDTVGPEGSKTPCQDQKSRDADSKSSHLLGEHCSDATLVLENPKKSCAMSLESSGNVSVQGEDVVSPVLELGEGPSAPESEDQESFSSAREEPTQQQTPLEARGEAVLAPEPIGGAGPSGRSEQEEHREDVPVAKDGVREPMGLADALQRELRLPKGDQEENAATQSRELAFEDDCTAELLQEIMGHLTVKDISVERITLDYSSYGDAQVHEGDFGHVTEIYDFSPSLKTEHLMEVFSDFHESGFKIQWVDDTHALGIFSSLSAASQALGRRYPSLKIRPLIHATKQSKIKALQRPKLLQLAKERPQTDTVVARRLVTRALGLKHQQQCGSGPEGLLPEGLDQEE", "length": 611, "header": "tr|A0A8V0ZIZ7-1|A0A8V0ZIZ7_CHICK Isoform 1 of R3H domain and coiled-coil containing 1 OS=Gallus gallus OX=9031 GN=R3HCC1 PE=1 SV=1 CANONICAL=A0A8V0ZIZ7-1" }, "locus": { "chromosome": "22", "start_pos": 1304718, "end_pos": 1297527, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048448.1", "url": "https://www.ensembl.org/id/ENSGALT00010048448.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028562.1", "url": "https://www.ensembl.org/id/ENSGALP00010028562.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 99, "start_aa": "Thr", "end_pos": 99, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr99", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1LZB0-1", "protein_name": "R3H domain and coiled-coil containing 1", "gene_name": "R3hcc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "FLYMLPQSLGIRGSECWGHGGFRGAYVIGGHGHFHLRQKQVSFTGPRASPPFDARQDKNTPLCGTCVISSRPHDGADSAGKKGTLRLLGTLSAAATFWAAAALPSVTLALLCLDGVFLSSAENDFVHRVQEELDRFLLQKQLSKVLLFPPVSSRLRYLIHRTAENFDLLSSFSVGEGWKRRTVICHLDIRLPNSDGPSGPCRPPASHPSKYRGPRYTSHQGAAAGPRGAPAGRWHRGRKPDQPLYVPRVLRRQDEPVAPSIPSLKGEDPAGGVSEEPREGGAAEAEADQGVPMLVTQETELLERPDPGYANEPQLELGDAEPSEDPEKEHGAEATVQQGSSPQLAMEEENRSQGMQSLVNQEEKVEGEEKEKVDEKEEDIGRQKERVGEEEGKTDVQNGQVDAEEEKMDEDEDKADGEEDNKDDADLDHFSELLQEITANLTEKEIEIEKIHLDTSAFTEELPGERDLTHLVEIYDFKPTLKTEDLLATFSEFQEKGFKIQWVDDTHAIGIFPCPASALEALAKDFSVLKIRPLTQGTKQSKLKALQRPKFLRLAKERPQTDSAVARRLVARALGLQQNKKKELPTPPSLLPS", "length": 593 }, "evidence": [ { "id": "A0A8V0ZIZ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BSI6-1", "protein_name": "R3H and coiled-coil domain-containing protein 1", "gene_name": "R3hcc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLCLDGVFLSSAENDFVHRVQEELDRFLLQKQLSKVLLFPPVSSRLRYLIHRTAENFDLLSSFSVGEGWKRRTVICHLDIRVPSSDGPSGPCRPPASHPSKYRGPRYTSHQGAAAGPRGAPAGRWHRGRKPDQPLYVPRVLRRQGGPVAASIPGIKGEDPAGAVSEEEPREAGAGDAEADQGIAMLVTQELLKSPDPGHANEPQMGLGDTEPSENPEKEQGAETAVQQGSGAQLAMEEENRSHGMRSLVDQEEEEIEGEEEEKVDEKEEDTGKQKERVDEEEEKTDAQEGKVDSEGERMDEGEDKVDAEEEDEDEADADHGDFSELLQEITANLTEKEIKIEKIHLDTSAFTEELPGERDLTHLVEIYDFKPTLKTEDLLATFSEFQEKGFRIQWVDDTHAIGIFPCPASALEALAKDFSVLKIRPLTQGTKQSKLKALQRPKFLRLSKERPQTDSAVARRLVARALGLQHNRKKELPTPPSVLPS", "length": 488 }, "evidence": [ { "id": "A0A8V0ZIZ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3T6-1", "protein_name": "R3H and coiled-coil domain-containing protein 1", "gene_name": "R3HCC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLCLDGVFLSSAENDFVHRIQEELDRFLLQKQLSKVLLFPPLSSRLRYLIHRTAENFDLLSSFSVGEGWKRRTVICHQDIRVPSSDGLSGPCRAPASCPSRYHGPRPISNQGAAAVPRGARAGRWYRGRKPDQPLYVPRVLRRQEEWGLTSTSVLKREAPAGRDPEEPGDVGAGDPNSDQGLPVLMTQGTEDLKGPGQRCENEPLLDPVGPEPLGPESQSGKGDMVEMATRFGSTLQLDLEKGKESLLEKRLVAEEEEDEEEVEEDGPSSCSEDDYSELLQEITDNLTKKEIQIEKIHLDTSSFVEELPGEKDLAHVVEIYDFEPALKTEDLLATFSEFQEKGFRIQWVDDTHALGIFPCLASAAEALTREFSVLKIRPLTQGTKQSKLKALQRPKLLRLVKERPQTNATVARRLVARALGLQHKKKERPAVRGPLPP", "length": 440 }, "evidence": [ { "id": "A0A8V0ZIZ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZIZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZIZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIZ7" }, { "id": "PS51061", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "R3H", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 76, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 99 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 }, { "start_pos": 322, "end_pos": 324 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJ53-1", "uniprot_ac": "A0A8V0ZJ53", "uniprot_id": "A0A8V0ZJ53_CHICK", "mass": { "chemical_mass": 41097.0, "monoisotopic_mass": 41097.0 }, "refseq": {}, "gene_names": [ { "name": "MORF4L2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ] } ], "protein_names": [ { "name": "Mortality factor 4-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MORF4L2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53", "locus": { "chromosome": "10", "start_pos": 19676869, "end_pos": 19699216, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020090", "url": "https://www.ensembl.org/id/ENSGALG00010020090" } ] } } ], "crossref": [ { "id": "A0A8V0ZJ53", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJ53", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18983", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18983", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "554283", "url": "https://www.ncbi.nlm.nih.gov/gene/554283", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBN5", "url": "https://www.orthodb.org/?gene=A0A8V0ZBN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBP4", "url": "https://www.orthodb.org/?gene=A0A8V0ZBP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD42", "url": "https://www.orthodb.org/?gene=A0A8V0ZD42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ44", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ53", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10880:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10880:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10880:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10880:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05712", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05712", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22732", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22732", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZBN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQKELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVFFRRDGAHTVCCLETPTISTRFGRKDSLQRTSPLKTKKNKQKTPGLGEGNSSSETPQPPRKKRARVDPTVESEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSSALFSASDYEVAPPEYHRKAV", "length": 357, "header": "tr|A0A8V0ZJ53-1|A0A8V0ZJ53_CHICK Isoform 1 of Mortality factor 4-like protein 1 OS=Gallus gallus OX=9031 GN=MORF4L2 PE=1 SV=1 CANONICAL=A0A8V0ZJ53-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZBN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53/entry#A0A8V0ZBN5-1", "sequence": { "sequence": "MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQKELQKANQKKRARVDPTVESEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSSALFSASDYEVAPPEYHRKAV", "length": 270, "header": "tr|A0A8V0ZBN5-1|A0A8V0ZJ53_CHICK Computationally mapped isoform of Mortality factor 4-like protein 1 OS=Gallus gallus OX=9031 GN=MORF4L2 PE=1 SV=1 CANONICAL=A0A8V0ZJ53-1" }, "locus": { "chromosome": "10", "start_pos": 19698997, "end_pos": 19677473, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048533.1", "url": "https://www.ensembl.org/id/ENSGALT00010048533.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028624.1", "url": "https://www.ensembl.org/id/ENSGALP00010028624.1" } ] } }, { "isoform_ac": "A0A8V0ZBP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53/entry#A0A8V0ZBP4-1", "sequence": { "sequence": "MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKKQKSEHFFLHWDEWVPESRVLKYVDTNLQKQKELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGLGEGNSSSETPQPPRKKRARVDPTVESEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSSALFSASDYEVAPPEYHRKAV", "length": 332, "header": "tr|A0A8V0ZBP4-1|A0A8V0ZJ53_CHICK Computationally mapped isoform of Mortality factor 4-like protein 1 OS=Gallus gallus OX=9031 GN=MORF4L2 PE=1 SV=1 CANONICAL=A0A8V0ZJ53-1" }, "locus": { "chromosome": "10", "start_pos": 19698997, "end_pos": 19677473, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048543.1", "url": "https://www.ensembl.org/id/ENSGALT00010048543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028634.1", "url": "https://www.ensembl.org/id/ENSGALP00010028634.1" } ] } }, { "isoform_ac": "A0A8V0ZD42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53/entry#A0A8V0ZD42-1", "sequence": { "sequence": "MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKKQKSEHFFLHWDEWVPESRVLKYVDTNLQKQKELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVFFRRDGAHTVCCLETPTISTRKTKKNKQKTPGLGEGNSSSETPQPPRKKRARVDPTVESEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSSALFSASDYEVAPPEYHRKAV", "length": 353, "header": "tr|A0A8V0ZD42-1|A0A8V0ZJ53_CHICK Computationally mapped isoform of Mortality factor 4-like protein 1 OS=Gallus gallus OX=9031 GN=MORF4L2 PE=1 SV=1 CANONICAL=A0A8V0ZJ53-1" }, "locus": { "chromosome": "10", "start_pos": 19698997, "end_pos": 19677473, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048539.1", "url": "https://www.ensembl.org/id/ENSGALT00010048539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028630.1", "url": "https://www.ensembl.org/id/ENSGALP00010028630.1" } ] } }, { "isoform_ac": "A0A8V0ZJ44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53/entry#A0A8V0ZJ44-1", "sequence": { "sequence": "MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQKELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVFFRRDGAHTVCCLETPTISTRKTKKNKQKTPGLGEGNSSSETPQPPRKKRARVDPTVESEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFGEYLAKNSSALFSASDYEVAPPEYHRKAV", "length": 317, "header": "tr|A0A8V0ZJ44-1|A0A8V0ZJ44_CHICK Computationally mapped isoform of Mortality factor 4-like protein 1 OS=Gallus gallus OX=9031 GN=MORF4L2 PE=1 SV=1 CANONICAL=A0A8V0ZJ53-1" }, "locus": { "chromosome": "10", "start_pos": 19698997, "end_pos": 19677473, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048527.1", "url": "https://www.ensembl.org/id/ENSGALT00010048527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028618.1", "url": "https://www.ensembl.org/id/ENSGALP00010028618.1" } ] } }, { "isoform_ac": "A0A8V0ZJ53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53/entry#A0A8V0ZJ53-1", "sequence": { "sequence": "MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQKELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVFFRRDGAHTVCCLETPTISTRFGRKDSLQRTSPLKTKKNKQKTPGLGEGNSSSETPQPPRKKRARVDPTVESEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSSALFSASDYEVAPPEYHRKAV", "length": 357, "header": "tr|A0A8V0ZJ53-1|A0A8V0ZJ53_CHICK Isoform 1 of Mortality factor 4-like protein 1 OS=Gallus gallus OX=9031 GN=MORF4L2 PE=1 SV=1 CANONICAL=A0A8V0ZJ53-1" }, "locus": { "chromosome": "10", "start_pos": 19698997, "end_pos": 19677473, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048537.1", "url": "https://www.ensembl.org/id/ENSGALT00010048537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028628.1", "url": "https://www.ensembl.org/id/ENSGALP00010028628.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" }, { "name": "Sin3-type complex", "id": "GO:0070822", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070822", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via homologous recombination", "id": "GO:1905168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ53" }, { "id": "SM00298", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00298" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromo", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 78, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 335, "end_pos": 337 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJJ0-1", "uniprot_ac": "A0A8V0ZJJ0", "uniprot_id": "A0A8V0ZJJ0_CHICK", "mass": { "chemical_mass": 43278.0, "monoisotopic_mass": 43278.0 }, "refseq": {}, "gene_names": [ { "name": "FAHD2A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0" } ] } ], "protein_names": [ { "name": "Fumarylacetoacetate hydrolase domain containing 2A", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAHD2A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0", "locus": { "chromosome": "22", "start_pos": 4635696, "end_pos": 4637570, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020149", "url": "https://www.ensembl.org/id/ENSGALG00010020149" } ] } } ], "crossref": [ { "id": "A0A8V0ZJJ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC24", "url": "https://www.orthodb.org/?gene=A0A8V0ZC24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDH7", "url": "https://www.orthodb.org/?gene=A0A8V0ZDH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJJ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZJJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42796", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42796", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42796:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42796:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZC24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RCLRHHRARPGWPRPGWRRRCPAPCACCASTAPGRPRPGWGWRWRRAGKWWTSARPSPRCPAPCAPSWRAARAAWRLPAGGGPEVVNGGRRWASRSGGRCGGREVAVRGARGVFLGCGGGVGVSRCVLGSPRRVPGVGAVFGAPKRALRPGGGCRCPPRSAPSRRALASGRHRLPRAGVRLLAPIDDPEKVICVGLNYRDHCLEQDVKVPKEPLIFSKFPSAIAGPFDDIVHPAESSEVDWEVELAAIIGKTGRHIQESVAMEHIVGFTVANDVSARDWQMRRNGRQWLLGKTFDTFCPIGPAIVTKDSVTDVHNLRIRCSVNGQLMQSSSTNQLIFRLPQLVAWVSQFVTLRPGDVLLTGTPPGVGVFRKPPMFLKPGDEVQCEIEELGTICNKVV", "length": 397, "header": "tr|A0A8V0ZJJ0-1|A0A8V0ZJJ0_CHICK Isoform 1 of Fumarylacetoacetate hydrolase domain containing 2A OS=Gallus gallus OX=9031 GN=FAHD2A PE=1 SV=1 CANONICAL=A0A8V0ZJJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZC24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0/entry#A0A8V0ZC24-1", "sequence": { "sequence": "MAPARLAAALPRAMRLLRFHGPGTAAPRLGLEVEEGGEVVDLGEAEPALPRSMRAFLESGESGLAAARRALASGRHRLPRAGVRLLAPIDDPEKVICVGLNYRDHCLEQDVKVPKEPLIFSKFPSAIAGPFDDIVHPAESSEVDWEVELAAIIGKTGRHIQESVAMEHIVGFTVANDVSARDWQMRRNGRQWLLGKTFDTFCPIGPAIVTKDSVTGLSHCALGMFC", "length": 226, "header": "tr|A0A8V0ZC24-1|A0A8V0ZJJ0_CHICK Computationally mapped isoform of Fumarylacetoacetate hydrolase domain containing 2A OS=Gallus gallus OX=9031 GN=FAHD2A PE=1 SV=1 CANONICAL=A0A8V0ZJJ0-1" }, "locus": { "chromosome": "22", "start_pos": 4637537, "end_pos": 4636173, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048672.1", "url": "https://www.ensembl.org/id/ENSGALT00010048672.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028759.1", "url": "https://www.ensembl.org/id/ENSGALP00010028759.1" } ] } }, { "isoform_ac": "A0A8V0ZDH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0/entry#A0A8V0ZDH7-1", "sequence": { "sequence": "MAPARLAAALPRAMRLLRFHGPGTAAPRLGLEVEEGGEVVDLGEAEPALPRSMRAFLESGESGLAAARRALASGRHRLPRAGVRLLAPIDDPEKVICVGLNYRDHCLEQDVKVPKEPLIFSKFPSAIAGPFDDIVHPAESSEVDWEVELAAIIGKTGRHIQESVAMEHIVGFTVANDVSARDWQMRRNGRQWLLGKTFDTFCPIGPAIVTKDSVTDVHNLRIRCSVNGQLMQSSSTNQLIFRLPQLVAWVSQFVTLRPGDVLLTGTPPGVGVFRKPPMFLKLLLEVEKPAAALPPQPPPHPSSLWGCRRSCYMHGAAASLAFAAR", "length": 325, "header": "tr|A0A8V0ZDH7-1|A0A8V0ZJJ0_CHICK Computationally mapped isoform of Fumarylacetoacetate hydrolase domain containing 2A OS=Gallus gallus OX=9031 GN=FAHD2A PE=1 SV=1 CANONICAL=A0A8V0ZJJ0-1" }, "locus": { "chromosome": "22", "start_pos": 4637537, "end_pos": 4635824, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048674.1", "url": "https://www.ensembl.org/id/ENSGALT00010048674.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028760.1", "url": "https://www.ensembl.org/id/ENSGALP00010028760.1" } ] } }, { "isoform_ac": "A0A8V0ZJJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0/entry#A0A8V0ZJJ0-1", "sequence": { "sequence": "RCLRHHRARPGWPRPGWRRRCPAPCACCASTAPGRPRPGWGWRWRRAGKWWTSARPSPRCPAPCAPSWRAARAAWRLPAGGGPEVVNGGRRWASRSGGRCGGREVAVRGARGVFLGCGGGVGVSRCVLGSPRRVPGVGAVFGAPKRALRPGGGCRCPPRSAPSRRALASGRHRLPRAGVRLLAPIDDPEKVICVGLNYRDHCLEQDVKVPKEPLIFSKFPSAIAGPFDDIVHPAESSEVDWEVELAAIIGKTGRHIQESVAMEHIVGFTVANDVSARDWQMRRNGRQWLLGKTFDTFCPIGPAIVTKDSVTDVHNLRIRCSVNGQLMQSSSTNQLIFRLPQLVAWVSQFVTLRPGDVLLTGTPPGVGVFRKPPMFLKPGDEVQCEIEELGTICNKVV", "length": 397, "header": "tr|A0A8V0ZJJ0-1|A0A8V0ZJJ0_CHICK Isoform 1 of Fumarylacetoacetate hydrolase domain containing 2A OS=Gallus gallus OX=9031 GN=FAHD2A PE=1 SV=1 CANONICAL=A0A8V0ZJJ0-1" }, "locus": { "chromosome": "22", "start_pos": 4637569, "end_pos": 4635769, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048680.1", "url": "https://www.ensembl.org/id/ENSGALT00010048680.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028763.1", "url": "https://www.ensembl.org/id/ENSGALP00010028763.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0" } ], "pmid": "" }, { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0" } ], "pmid": "" }, { "name": "oxaloacetate tautomerase activity", "id": "GO:0050163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050163", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "small molecule metabolic process", "id": "GO:0044281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0" } ], "pmid": "" }, { "name": "oxaloacetate metabolic process", "id": "GO:0006107", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006107", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ0" }, { "id": "PF01557", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01557" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fumarylacetoacetase-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 190, "end_pos": 397, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJG6-1", "uniprot_ac": "A0A8V0ZJG6", "uniprot_id": "A0A8V0ZJG6_CHICK", "mass": { "chemical_mass": 40157.0, "monoisotopic_mass": 40157.0 }, "refseq": {}, "gene_names": [ { "name": "MSI1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" } ] } ], "protein_names": [ { "name": "RNA-binding protein Musashi homolog 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCA6#function" }, { "database": "UniProtKB", "id": "ARBA00058359", "url": "https://www.uniprot.org/uniprotkb/ARBA00058359#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX4#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MSI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6", "locus": { "chromosome": "15", "start_pos": 9372589, "end_pos": 9302199, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021383", "url": "https://www.ensembl.org/id/ENSGALG00010021383" } ] } } ], "crossref": [ { "id": "A0A8V0ZJG6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12323", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12323", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12576", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12576", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416979", "url": "https://www.ncbi.nlm.nih.gov/gene/416979", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCA6", "url": "https://www.orthodb.org/?gene=A0A8V0ZCA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHX0", "url": "https://www.orthodb.org/?gene=A0A8V0ZHX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHX4", "url": "https://www.orthodb.org/?gene=A0A8V0ZHX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJE5", "url": "https://www.orthodb.org/?gene=A0A8V0ZJE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJG1", "url": "https://www.orthodb.org/?gene=A0A8V0ZJG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJG6", "url": "https://www.orthodb.org/?gene=A0A8V0ZJG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ91", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48032", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48032", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48032:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48032:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPGWCLFPETPPSTLSPSWGASAGCRRQQTGTSAPQLAPSKMFIGGLSWQTTQEGLREYFSQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQAATYASRSYTGIAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH", "length": 372, "header": "tr|A0A8V0ZJG6-1|A0A8V0ZJG6_CHICK Isoform 1 of RNA-binding protein Musashi homolog 1 OS=Gallus gallus OX=9031 GN=MSI1 PE=1 SV=1 CANONICAL=A0A8V0ZJG6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6/entry#A0A8V0ZCA6-1", "sequence": { "sequence": "METDGSQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFSQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQAATYASRSYTGIAPGYTYQFPAIPLTAYGPMAAAAAAAAVVRGTGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH", "length": 332, "header": "tr|A0A8V0ZCA6-1|A0A8V0ZJG6_CHICK Computationally mapped isoform of RNA-binding protein Musashi homolog 1 OS=Gallus gallus OX=9031 GN=MSI1 PE=1 SV=1 CANONICAL=A0A8V0ZJG6-1" }, "locus": { "chromosome": "15", "start_pos": 9369371, "end_pos": 9344287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051813.1", "url": "https://www.ensembl.org/id/ENSGALT00010051813.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030907.1", "url": "https://www.ensembl.org/id/ENSGALP00010030907.1" } ] } }, { "isoform_ac": "A0A8V0ZHX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6/entry#A0A8V0ZHX0-1", "sequence": { "sequence": "METDGSQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFSQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMCKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQAATYASRSYTGIAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH", "length": 349, "header": "tr|A0A8V0ZHX0-1|A0A8V0ZJG6_CHICK Computationally mapped isoform of RNA-binding protein Musashi homolog 1 OS=Gallus gallus OX=9031 GN=MSI1 PE=1 SV=1 CANONICAL=A0A8V0ZJG6-1" }, "locus": { "chromosome": "15", "start_pos": 9369371, "end_pos": 9344287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051816.1", "url": "https://www.ensembl.org/id/ENSGALT00010051816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030909.1", "url": "https://www.ensembl.org/id/ENSGALP00010030909.1" } ] } }, { "isoform_ac": "A0A8V0ZHX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6/entry#A0A8V0ZHX4-1", "sequence": { "sequence": "MQKKSYLLHWQNFRMMNPSFLQTCAGICHCKMFIGGLSWQTTQEGLREYFSQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQAATYASRSYTGIAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH", "length": 361, "header": "tr|A0A8V0ZHX4-1|A0A8V0ZJG6_CHICK Computationally mapped isoform of RNA-binding protein Musashi homolog 1 OS=Gallus gallus OX=9031 GN=MSI1 PE=1 SV=1 CANONICAL=A0A8V0ZJG6-1" }, "locus": { "chromosome": "15", "start_pos": 9369371, "end_pos": 9324155, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051825.1", "url": "https://www.ensembl.org/id/ENSGALT00010051825.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030914.1", "url": "https://www.ensembl.org/id/ENSGALP00010030914.1" } ] } }, { "isoform_ac": "A0A8V0ZJE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6/entry#A0A8V0ZJE5-1", "sequence": { "sequence": "MVLPVETPGTRRSQNTKASEQSSKMFIGGLSWQTTQEGLREYFSQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQAATYASRSYTGIAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH", "length": 354, "header": "tr|A0A8V0ZJE5-1|A0A8V0ZJE5_CHICK Computationally mapped isoform of RNA-binding protein Musashi homolog 1 OS=Gallus gallus OX=9031 GN=MSI1 PE=1 SV=1 CANONICAL=A0A8V0ZJG6-1" }, "locus": { "chromosome": "15", "start_pos": 9369371, "end_pos": 9302398, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051827.1", "url": "https://www.ensembl.org/id/ENSGALT00010051827.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030916.1", "url": "https://www.ensembl.org/id/ENSGALP00010030916.1" } ] } }, { "isoform_ac": "A0A8V0ZJG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6/entry#A0A8V0ZJG1-1", "sequence": { "sequence": "METDGSQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFSQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQAATYASRSYTGIAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTVLLPPVGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH", "length": 343, "header": "tr|A0A8V0ZJG1-1|A0A8V0ZJG1_CHICK Computationally mapped isoform of Musashi RNA binding protein 1 OS=Gallus gallus OX=9031 GN=MSI1 PE=1 SV=1 CANONICAL=A0A8V0ZJG6-1" }, "locus": { "chromosome": "15", "start_pos": 9369371, "end_pos": 9344287, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051810.1", "url": "https://www.ensembl.org/id/ENSGALT00010051810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030905.1", "url": "https://www.ensembl.org/id/ENSGALP00010030905.1" } ] } }, { "isoform_ac": "A0A8V0ZJG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6/entry#A0A8V0ZJG6-1", "sequence": { "sequence": "MPPGWCLFPETPPSTLSPSWGASAGCRRQQTGTSAPQLAPSKMFIGGLSWQTTQEGLREYFSQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQAATYASRSYTGIAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH", "length": 372, "header": "tr|A0A8V0ZJG6-1|A0A8V0ZJG6_CHICK Isoform 1 of RNA-binding protein Musashi homolog 1 OS=Gallus gallus OX=9031 GN=MSI1 PE=1 SV=1 CANONICAL=A0A8V0ZJG6-1" }, "locus": { "chromosome": "15", "start_pos": 9369371, "end_pos": 9328614, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051819.1", "url": "https://www.ensembl.org/id/ENSGALT00010051819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030910.1", "url": "https://www.ensembl.org/id/ENSGALP00010030910.1" } ] } }, { "isoform_ac": "A0A8V0ZQ91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6/entry#A0A8V0ZQ91-1", "sequence": { "sequence": "MSRRAAELNKAVRGAEETRLPLGCLNCWQIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQAATYASRSYTGIAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH", "length": 291, "header": "tr|A0A8V0ZQ91-1|A0A8V0ZQ91_CHICK Computationally mapped isoform of Musashi RNA binding protein 1 OS=Gallus gallus OX=9031 GN=MSI1 PE=1 SV=1 CANONICAL=A0A8V0ZJG6-1" }, "locus": { "chromosome": "15", "start_pos": 9369371, "end_pos": 9348418, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051804.1", "url": "https://www.ensembl.org/id/ENSGALT00010051804.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030903.1", "url": "https://www.ensembl.org/id/ENSGALP00010030903.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 310, "start_aa": "Thr", "end_pos": 310, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr310", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" } ], "pmid": "" }, { "name": "poly(U) RNA binding", "id": "GO:0008266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG6" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 131, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 310 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ 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"uniprot_canonical_ac": "A0A8V0ZJQ8-1", "uniprot_ac": "A0A8V0ZJQ8", "uniprot_id": "A0A8V0ZJQ8_CHICK", "mass": { "chemical_mass": 93759.0, "monoisotopic_mass": 93759.0 }, "refseq": {}, "gene_names": [ { "name": "PRICKLE2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8" } ] } ], "protein_names": [ { "name": "Prickle planar cell polarity protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], 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Classification" ] }, { "id": "PTHR24211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLEMEKTVTKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQYYSCLPEDKVPYVNSPGEKSRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFICSVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKDGRPYCCSCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAQCKKSLLGRPFLPKQGQIFCSRACSVGDDPNGSDSSDSAFQSARAKESRRSAKIGKNKGKAEEAALSQLQVTSNRLSTDVDPLSLQMDLLSLASQTPSLNREHVWRSRDELYHYGSKMEQGQAQSPLQLLSQCNIRTSYNPSQVPGSQPDLWAKHFNNPKRSSSLAMKGHGGSFIQDCREDYYSGRLRSQESYSDMSNQSFPETRGSLKVPKYEEEEEGGMPTPQCRTRHPINALKFTEDLTPTEQTPRGSMESLALSNATGLSADVGAKRQEHLSRFSMPDLSKDSGMNVSEKLSTMGTLNSSVQFRSAESVRSLLSAQQYQDLEPNLHDLASPMGYRERPAHGRLHQSFDYGSGVPGGKLAAQDGTRHAPMSERTRRRTPLRDDERHYRPHRPRRSRRSRSDNALHLASEQCCRLKERPSLRARDDYDQFMHQRSCRESLEQGPRRDAYGHCPRTVSDLALQNHLGERWGPYFAEYDWCSTCSSSSESDNEGYFLGEPIPQPARLRYVTSEELLHKYGSYSMPKSSTLGGRGQLHSRKRQKSKNCIIS", "length": 829, "header": "tr|A0A8V0ZJQ8-1|A0A8V0ZJQ8_CHICK Isoform 1 of Prickle planar cell polarity protein 2 OS=Gallus gallus OX=9031 GN=PRICKLE2 PE=3 SV=1 CANONICAL=A0A8V0ZJQ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8/entry#A0A8V0ZCB1-1", "sequence": { "sequence": "MPRLRPAQVEICLHCKCSQEEHIVTVMPLEMEKTVTKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEDKVPYVNSPGEKSRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFICSVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKDGRPYCCSCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAQCKKSLLGRPFLPKQGQIFCSRACSVGDDPNGSDSSDSAFQSARAKESRRSAKIGKNKGKAEEAALSQLQVTSNRLSTDVDPLSLQMDLLSLASQTPSLNREHVWRSRDELYHYGSKMEQGQAQSPLQLLSQCNIRTSYNPSQVPGSQPDLWAKHFNNPKRSSSLAMKGHGGSFIQDCREDYYSGRLRSQESYSDMSNQSFPETRGSLKVPKYEEEEEGGMPTPQCRTRHPINALKFTEDLTPTEQTPRGSMESLALSNATGLSADVGAKRQEHLSRFSMPDLSKDSGMNVSEKLSTMGTLNSSVQFRSAESVRSLLSAQQYQDLEPNLHDLASPMGYRERPAHGRLHQSFDYGSGVPGGKLAAQDGTRHAPMSERTRRRTPLRDDERHYRPHRPRRSRRSRSDNALHLASEQCCRLKERPSLRARDDYDQFMHQRSCRESLEQGPRRDAYGHCPRTVSDLALQNHLGERWGPYFAEYDWCSTCSSSSESDNEGYFLGEPIPQPARLRYVTSEELLHKYGSYSMPKSSTLGGRGQLHSRKRQKSKNCIIS", "length": 858, "header": "tr|A0A8V0ZCB1-1|A0A8V0ZJQ8_CHICK Computationally mapped isoform of Prickle planar cell polarity protein 2 OS=Gallus gallus OX=9031 GN=PRICKLE2 PE=3 SV=1 CANONICAL=A0A8V0ZJQ8-1" }, "locus": { "chromosome": "12", "start_pos": 13906920, "end_pos": 13818949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048789.1", "url": "https://www.ensembl.org/id/ENSGALT00010048789.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028844.1", "url": "https://www.ensembl.org/id/ENSGALP00010028844.1" } ] } }, { "isoform_ac": "A0A8V0ZDP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8/entry#A0A8V0ZDP5-1", "sequence": { "sequence": "MLTLWRLTEQTVHQYYSCLPEDKVPYVNSPGEKSRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFICSVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKDGRPYCCSCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAQCKKSLLGRPFLPKQGQIFCSRACSVGDDPNGSDSSDSAFQSARAKESRRSAKIGKNKGKAEEAALSQLQVTSNRLSTDVDPLSLQMDLLSLASQTPSLNREHVWRSRDELYHYGSKMEQGQAQSPLQLLSQCNIRTSYNPSQVPGSQPDLWAKHFNNPKRSSSLAMKGHGGSFIQDCREDYYSGRLRSQESYSDMSNQSFPETRGSLKVPKYEEEEEGGMPTPQCRTRHPINALKFTEDLTPTEQTPRGSMESLALSNATGLSADVGAKRQEHLSRFSMPDLSKDSGMNVSEKLSTMGTLNSSVQFRSAESVRSLLSAQQYQDLEPNLHDLASPMGYRERPAHGRLHQSFDYGSGVPGGKLAAQDGTRHAPMSERTRRRTPLRDDERHYRPHRPRRSRRSRSDNALHLASEQCCRLKERPSLRARDDYDQFMHQRSCRESLEQGPRRDAYGHCPRTVSDLALQNHLGERWGPYFAEYDWCSTCSSSSESDNEGYFLGEPIPQPARLRYVTSEELLHKYGSYSMPKSSTLGGRGQLHSRKRQKSKNCIIS", "length": 799, "header": "tr|A0A8V0ZDP5-1|A0A8V0ZJQ8_CHICK Computationally mapped isoform of Prickle planar cell polarity protein 2 OS=Gallus gallus OX=9031 GN=PRICKLE2 PE=3 SV=1 CANONICAL=A0A8V0ZJQ8-1" }, "locus": { "chromosome": "12", "start_pos": 13835895, "end_pos": 13818949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048771.1", "url": "https://www.ensembl.org/id/ENSGALT00010048771.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028830.1", "url": "https://www.ensembl.org/id/ENSGALP00010028830.1" } ] } }, { "isoform_ac": "A0A8V0ZDQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8/entry#A0A8V0ZDQ5-1", "sequence": { "sequence": "MYLSHTRSQLFPFMNNMLCASLSFRIQIFFSSLYVYLKGFGDMRTAMPYLEQAYALIASPVSGVGSCGVLFRYPFCSGEPTGMGKLCQRGALLQRKICLHCKCSQEEHIVTVMPLEMEKTVTKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQVHQYYSCLPEDKVPYVNSPGEKSRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFICSVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKDGRPYCCSCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAQCKKSLLGRPFLPKQGQIFCSRACSVGDDPNGSDSSDSAFQSARAKESRRSAKIGKNKGKAEEAALSQLQVTSNRLSTDVDPLSLQMDLLSLASQTPSLNREHVWRSRDELYHYGSKMEQGQAQSPLQLLSQCNIRTSYNPSQVPGSQPDLWAKHFNNPKRSSSLAMKGHGGSFIQDCREDYYSGRLRSQESYSDMSNQSFPETRGSLKVPKYEEEEEGGMPTPQCRTRHPINALKFTEDLTPTEQTPRGSMESLALSNATGLSADVGAKRQEHLSRFSMPDLSKDSGMNVSEKLSTMGTLNSSVQFRSAESVRSLLSAQQYQDLEPNLHDLASPMGYRERPAHGRLHQSFDYGSGVPGGKLAAQDGTRHAPMSERTRRRTPLRDDERHYRPHRPRRSRRSRSDNALHLASEQCCRLKERPSLRARDDYDQFMHQRSCRESLEQGPRRDAYGHCPRTVSDLALQNHLGERWGPYFAEYDWCSTCSSSSESDNEGYFLGEPIPQPARLRYVTSEELLHKYGSYSMPKSSTLGGRGQLHSRKRQKSKNCIIS", "length": 944, "header": "tr|A0A8V0ZDQ5-1|A0A8V0ZJQ8_CHICK Computationally mapped isoform of Prickle planar cell polarity protein 2 OS=Gallus gallus OX=9031 GN=PRICKLE2 PE=3 SV=1 CANONICAL=A0A8V0ZJQ8-1" }, "locus": { "chromosome": "12", "start_pos": 13902265, "end_pos": 13818949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048784.1", "url": "https://www.ensembl.org/id/ENSGALT00010048784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028840.1", "url": "https://www.ensembl.org/id/ENSGALP00010028840.1" } ] } }, { "isoform_ac": "A0A8V0ZJQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8/entry#A0A8V0ZJQ3-1", "sequence": { "sequence": "MLYKCKVHQYYSCLPEDKVPYVNSPGEKSRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFICSVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKDGRPYCCSCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAQCKKSLLGRPFLPKQGQIFCSRACSVGDDPNGSDSSDSAFQSARAKESRRSAKIGKNKGKAEEAALSQLQVTSNRLSTDVDPLSLQMDLLSLASQTPSLNREHVWRSRDELYHYGSKMEQGQAQSPLQLLSQCNIRTSYNPSQVPGSQPDLWAKHFNNPKRSSSLAMKGHGGSFIQDCREDYYSGRLRSQESYSDMSNQSFPETRGSLKVPKYEEEEEGGMPTPQCRTRHPINALKFTEDLTPTEQTPRGSMESLALSNATGLSADVGAKRQEHLSRFSMPDLSKDSGMNVSEKLSTMGTLNSSVQFRSAESVRSLLSAQQYQDLEPNLHDLASPMGYRERPAHGRLHQSFDYGSGVPGGKLAAQDGTRHAPMSERTRRRTPLRDDERHYRPHRPRRSRRSRSDNALHLASEQCCRLKERPSLRARDDYDQFMHQRSCRESLEQGPRRDAYGHCPRTVSDLALQNHLGERWGPYFAEYDWCSTCSSSSESDNEGYFLGEPIPQPARLRYVTSEELLHKYGSYSMPKSSTLGGRGQLHSRKRQKSKNCIIS", "length": 794, "header": "tr|A0A8V0ZJQ3-1|A0A8V0ZJQ3_CHICK Computationally mapped isoform of Prickle planar cell polarity protein 2 OS=Gallus gallus OX=9031 GN=PRICKLE2 PE=3 SV=1 CANONICAL=A0A8V0ZJQ8-1" }, "locus": { "chromosome": "12", "start_pos": 13836836, "end_pos": 13818949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048775.1", "url": "https://www.ensembl.org/id/ENSGALT00010048775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028833.1", "url": "https://www.ensembl.org/id/ENSGALP00010028833.1" } ] } }, { "isoform_ac": "A0A8V0ZJQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8/entry#A0A8V0ZJQ8-1", "sequence": { "sequence": "MPLEMEKTVTKLMFDFQRNSTSDDDSGCALEEYAWVPPGLKPEQYYSCLPEDKVPYVNSPGEKSRIKQLLHQLPPHDNEVRYCNSLDEEEKRELKLFSNQRKRENLGRGNVRPFPVTMTGAICEQCGGQINGGDIAVFASRAGHGVCWHPPCFICSVCNELLVDLIYFYQDGKIYCGRHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKDGRPYCCSCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATETCFCCAQCKKSLLGRPFLPKQGQIFCSRACSVGDDPNGSDSSDSAFQSARAKESRRSAKIGKNKGKAEEAALSQLQVTSNRLSTDVDPLSLQMDLLSLASQTPSLNREHVWRSRDELYHYGSKMEQGQAQSPLQLLSQCNIRTSYNPSQVPGSQPDLWAKHFNNPKRSSSLAMKGHGGSFIQDCREDYYSGRLRSQESYSDMSNQSFPETRGSLKVPKYEEEEEGGMPTPQCRTRHPINALKFTEDLTPTEQTPRGSMESLALSNATGLSADVGAKRQEHLSRFSMPDLSKDSGMNVSEKLSTMGTLNSSVQFRSAESVRSLLSAQQYQDLEPNLHDLASPMGYRERPAHGRLHQSFDYGSGVPGGKLAAQDGTRHAPMSERTRRRTPLRDDERHYRPHRPRRSRRSRSDNALHLASEQCCRLKERPSLRARDDYDQFMHQRSCRESLEQGPRRDAYGHCPRTVSDLALQNHLGERWGPYFAEYDWCSTCSSSSESDNEGYFLGEPIPQPARLRYVTSEELLHKYGSYSMPKSSTLGGRGQLHSRKRQKSKNCIIS", "length": 829, "header": "tr|A0A8V0ZJQ8-1|A0A8V0ZJQ8_CHICK Isoform 1 of Prickle planar cell polarity protein 2 OS=Gallus gallus OX=9031 GN=PRICKLE2 PE=3 SV=1 CANONICAL=A0A8V0ZJQ8-1" }, "locus": { "chromosome": "12", "start_pos": 13845685, "end_pos": 13818949, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048781.1", "url": "https://www.ensembl.org/id/ENSGALT00010048781.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028838.1", "url": "https://www.ensembl.org/id/ENSGALP00010028838.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 121, "end_pos": 185, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZJQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ8" }, { "id": "PS51303", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51303" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PET", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 119, "start_aa": "Phe", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 477, "end_pos": 479 }, { "start_pos": 538, "end_pos": 540 }, { "start_pos": 569, "end_pos": 571 }, { "start_pos": 581, "end_pos": 583 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJQ9-1", "uniprot_ac": "A0A8V0ZJQ9", "uniprot_id": "A0A8V0ZJQ9_CHICK", "mass": { "chemical_mass": 34088.0, "monoisotopic_mass": 34088.0 }, "refseq": {}, "gene_names": [ { "name": "UQCC1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ9" } ] } ], "protein_names": [ { "name": "Ubiquinol-cytochrome c reductase complex assembly factor 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJQ9", "database": "UniProtKB", "url": 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"MAALARAASCQAEVTQWVAACSGLLQTATVQGQCRRMLHGIFQRCKTGQFQLPKACGGLIEANGAKTHQNRLIYSTSKQLSAKDSVQTSEEKVGPFTRIIEAMGFTGPLKYSRWKIKVAALRMYTCCVEKTDYEEFFNRCQMPDTLNSWFLVAQLHVWMCLVRMKQEGRAGKYMCRYIVHCMWEDVEQRGKVMGINSVVLKQDLRSMVENFYAALFGYDEGILSDDHVLAAALWRNLFNRNCEDPQHLELLVEYVRKQHLDALSGEDLLLTGEVSWRPLVESNARSILKPLSPVYNDEGL", "length": 300, "header": "tr|A0A8V0ZJQ9-1|A0A8V0ZJQ9_CHICK Isoform 1 of Ubiquinol-cytochrome c reductase complex assembly factor 1 OS=Gallus gallus OX=9031 GN=UQCC1 PE=1 SV=1 CANONICAL=A0A8V0ZJQ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ9/entry#A0A8V0ZCJ9-1", "sequence": { "sequence": "MAALARAASCQAEVTQWVAACSGLLQTATVQGQCRRMLHGIFQRCKTGQFQLPKACGGLIEANGAKTHQNRLIYSTSKQLSAKDSVQTSEEKVGPFTRIIEAMGFTGPLKYSRWKIKVAALRMYTCCVEKTDYEEFFNRCQMPDTLNSWFLVAQLHVWMCLVRMKQEGRAGKYMCRYIVHCMWEDVEQRGKVMGGILSDDHVLAAALWRNLFNRNCEDPQHLELLVEYVRKQVQHLDALSGEDLLLTGEVSWRPLVESNARSILKPLSPVYNDEGL", "length": 276, "header": "tr|A0A8V0ZCJ9-1|A0A8V0ZJQ9_CHICK Computationally mapped isoform of Ubiquinol-cytochrome c reductase complex assembly factor 1 OS=Gallus gallus OX=9031 GN=UQCC1 PE=1 SV=1 CANONICAL=A0A8V0ZJQ9-1" }, "locus": { "chromosome": "20", "start_pos": 1636006, "end_pos": 1584562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051932.1", "url": "https://www.ensembl.org/id/ENSGALT00010051932.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030992.1", "url": "https://www.ensembl.org/id/ENSGALP00010030992.1" } ] } }, { "isoform_ac": "A0A8V0ZJK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ9/entry#A0A8V0ZJK3-1", "sequence": { "sequence": "MAALARAASCQAEVTQWVAACSGLLQTATVQGQCRRMLHGIFQRCKTGQFQLPKACGGLIEANGAKTHQNRLIYSTSKQLSAKDSVQTSEEKVGPFTRIIEAMGFTGPLKYSRWKIKVAALRMYTCCVEKTDYEEFFNRCQMPDTLNSWFLVAQLHVWMCLVRMKQEGRAGKYMCRYIVHCMWEDVEQRGKVMGGLKQQQAAKRSKTVCYSDKHAELKNEAWFSWMCWMLLLYSNLSLVCFVPPPDACKNYTGSCLVPFQGMLLPLFPTFYTCETHVPKLILLCRAVGAKCCPVLLKSQSMA", "length": 302, "header": "tr|A0A8V0ZJK3-1|A0A8V0ZJK3_CHICK Computationally mapped isoform of Ubiquinol-cytochrome c reductase complex assembly factor 1 OS=Gallus gallus OX=9031 GN=UQCC1 PE=1 SV=1 CANONICAL=A0A8V0ZJQ9-1" }, "locus": { "chromosome": "20", "start_pos": 1616811, "end_pos": 1584562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051876.1", "url": "https://www.ensembl.org/id/ENSGALT00010051876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030950.1", "url": "https://www.ensembl.org/id/ENSGALP00010030950.1" } ] } }, { "isoform_ac": "A0A8V0ZJQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ9/entry#A0A8V0ZJQ9-1", "sequence": { "sequence": "MAALARAASCQAEVTQWVAACSGLLQTATVQGQCRRMLHGIFQRCKTGQFQLPKACGGLIEANGAKTHQNRLIYSTSKQLSAKDSVQTSEEKVGPFTRIIEAMGFTGPLKYSRWKIKVAALRMYTCCVEKTDYEEFFNRCQMPDTLNSWFLVAQLHVWMCLVRMKQEGRAGKYMCRYIVHCMWEDVEQRGKVMGINSVVLKQDLRSMVENFYAALFGYDEGILSDDHVLAAALWRNLFNRNCEDPQHLELLVEYVRKQHLDALSGEDLLLTGEVSWRPLVESNARSILKPLSPVYNDEGL", "length": 300, "header": "tr|A0A8V0ZJQ9-1|A0A8V0ZJQ9_CHICK Isoform 1 of Ubiquinol-cytochrome c reductase complex assembly factor 1 OS=Gallus gallus OX=9031 GN=UQCC1 PE=1 SV=1 CANONICAL=A0A8V0ZJQ9-1" }, "locus": { "chromosome": "20", "start_pos": 1636006, "end_pos": 1584562, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051946.1", "url": "https://www.ensembl.org/id/ENSGALT00010051946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031000.1", "url": "https://www.ensembl.org/id/ENSGALP00010031000.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ9" } ], 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"reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJQ9" }, { "id": "PF03981", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03981" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquinol-cytochrome c chaperone", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 272, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"uniprot_id": "A0A8V0ZJU1_CHICK", "mass": { "chemical_mass": 103309.0, "monoisotopic_mass": 103309.0 }, "refseq": { "ac": "XP_421748", "name": "cilia- and flagella-associated protein 58 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421748" }, "gene_names": [ { "name": "CFAP58", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1" } ] }, { "name": "CFAP58", "type": "synonym", "evidence": [ { "id": "XP_421748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421748" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 58", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 58 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_421748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421748" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_421748.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421748" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1", "locus": { "chromosome": "6", "start_pos": 25129840, "end_pos": 25074368, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021455", "url": "https://www.ensembl.org/id/ENSGALG00010021455" } ] } } ], "crossref": [ { "id": "A0A8V0ZJU1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "423882", "url": "https://www.ncbi.nlm.nih.gov/gene/423882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR049270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CQDDMRL", "url": "https://omabrowser.org/oma/group/CQDDMRL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCQ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZCQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJU1", "url": "https://www.orthodb.org/?gene=A0A8V0ZJU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32083:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32083:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421748", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEEEKSAKLYLEESAFEALEKDFEEVINLLKGDNTLEKFRTEYEKLYAVLKKSHENEKRLMEKCRQLNAELVVNSSKVAALTKLSKDDRGTISSMKAEIEKAWKMVDAAYEKEQKAKETIHSLQEEIAHLTNSVEQGSGLSSSQEYNISELIKYKEEITKERDQLLSEVVELRQSLTQATEQQQDAERAKDEADQAIMQLQQEIQMRNNEVSREVRKKEKMEKELKNLQAEIVNKQTEIKNLQQRIQKNKEEQLKVEQHLKEQMMLNERTGKELEQFQMRNNKLVQESEHHSVMFQGVVQDLQKKTAELKARDDELTQMHLEISKMNKVRDVLQSKLRAAEDKKVAAGHERETLKRQISGLERELEAAKKQAEIDKKAIDDLVRERDTLSKNLNKATNAVQKQTDLVKLHEQSKKNLEDEIQNYKNEAQKQRKIIYQLEKERDCFINEASDLKQKVLQHLKDVEIREVKICDYEKKIEESEMKLKQQQNRCETVRTERNLYSKNLIEAKDEITEMRKRLKTVTHQGDQLKEEITKKEEALVKAQLEHQQLEREKESLKAELLKMKKQALETKNFIENQEAEERKLLKIIAEADAERLKQNKEYDRVINERDVLGSQLVRRNDEVALLYEKIKIQQSILNKGETQYRQRMEDIRLLKLEIRKLRREKGILGKTVANVEELRQEVHHMRKELLREQTRCKVLEEELENPLNVHRWRKLEASDPSTYELIQKIQRLQKQLISKTGEVIEKELLLQEKEKLYVELKHVLARQPGPEAAEQLQLYRHTLREKTKQLKILSSELNMYESQSQEYKYEIERLANELLNVKKKYLAQKRKEQQAKEKERSLAESEFPHLRSDVPRFTGGGFALSRPVPKVTA", "length": 875, "header": "tr|A0A8V0ZJU1-1|A0A8V0ZJU1_CHICK Isoform 1 of Cilia and flagella associated protein 58 OS=Gallus gallus OX=9031 GN=CFAP58 PE=4 SV=1 CANONICAL=A0A8V0ZJU1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1/entry#A0A8V0ZCQ2-1", "sequence": { "sequence": "MEKSAKLYLEESAFEALEKDFEEVINLLKGDNTLEKFRTEYEKLYAVLKKSHENEKRLMEKCRQLNAELVVNSSKVAALTKLSKDDRGTISSMKAEIEKAWKMVDAAYEKEQKAKETIHSLQEEIAHLTNSVEQGSGLSSSQEYNISELIKYKEEITKERDQLLSEVVELRQSLTQATEQQQDAERAKDEADQAIMQLQQEIQMRNNEVSREVRKKEKMEKELKNLQAEIVNKQTEIKNLQQRIQKNKEEQLKVEQHLKEQMMLNERTGKELEQFQMRNNKLVQESEHHSVMFQGVVQDLQKKTAELKARDDELTQMHLEISKMNKVRDVLQSKLRAAEDKKVAAGHERETLKRQISGLERELEAAKKQAEIDKKAIDDLVRERDTLSKNLNKATNAVQKQTDLVKLHEQSKKNLEDEIQNYKNEAQKQRKIIYQLEKERDCFINEASDLKQKVLQHLKDVEIREVKICDYEKKIEESEMKLKQQQNRCETVRTERNLYSKNLIEAKDEITEMRKRLKTVTHQGDQLKEEITKKEEALVKAQLEHQQLEREKESLKAELLKMKKQALETKNFIENQEAEERKLLKIIAEADAERLKQNKEYDRVINERDVLGSQLVRRNDEVALLYEKIKIQQSILNKGETQYRQRMEDIRLLKLEIRKLRREKGILGKTVANVEELRQEVHHMRKELLREQTRCKVLEEELENPLNVHRWRKLEASDPSTYELIQKIQRLQKQLISKTGEVIEKELLLQEKEKLYVELKHVLARQPGPEAAEQLQLYRHTLREKTKQLKILSSELNMYESQSQEYKYEIERLANELLNVKKKYLAQKRKEQQAKEKERSLAESEFPHLRSDVPRFTGGGFALSRPVPKVTA", "length": 872, "header": "tr|A0A8V0ZCQ2-1|A0A8V0ZJU1_CHICK Computationally mapped isoform of Cilia and flagella associated protein 58 OS=Gallus gallus OX=9031 GN=CFAP58 PE=4 SV=1 CANONICAL=A0A8V0ZJU1-1" }, "locus": { "chromosome": "6", "start_pos": 25128912, "end_pos": 25075167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052014.1", "url": "https://www.ensembl.org/id/ENSGALT00010052014.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031048.1", "url": "https://www.ensembl.org/id/ENSGALP00010031048.1" } ] } }, { "isoform_ac": "A0A8V0ZJU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1/entry#A0A8V0ZJU1-1", "sequence": { "sequence": "MEEEEKSAKLYLEESAFEALEKDFEEVINLLKGDNTLEKFRTEYEKLYAVLKKSHENEKRLMEKCRQLNAELVVNSSKVAALTKLSKDDRGTISSMKAEIEKAWKMVDAAYEKEQKAKETIHSLQEEIAHLTNSVEQGSGLSSSQEYNISELIKYKEEITKERDQLLSEVVELRQSLTQATEQQQDAERAKDEADQAIMQLQQEIQMRNNEVSREVRKKEKMEKELKNLQAEIVNKQTEIKNLQQRIQKNKEEQLKVEQHLKEQMMLNERTGKELEQFQMRNNKLVQESEHHSVMFQGVVQDLQKKTAELKARDDELTQMHLEISKMNKVRDVLQSKLRAAEDKKVAAGHERETLKRQISGLERELEAAKKQAEIDKKAIDDLVRERDTLSKNLNKATNAVQKQTDLVKLHEQSKKNLEDEIQNYKNEAQKQRKIIYQLEKERDCFINEASDLKQKVLQHLKDVEIREVKICDYEKKIEESEMKLKQQQNRCETVRTERNLYSKNLIEAKDEITEMRKRLKTVTHQGDQLKEEITKKEEALVKAQLEHQQLEREKESLKAELLKMKKQALETKNFIENQEAEERKLLKIIAEADAERLKQNKEYDRVINERDVLGSQLVRRNDEVALLYEKIKIQQSILNKGETQYRQRMEDIRLLKLEIRKLRREKGILGKTVANVEELRQEVHHMRKELLREQTRCKVLEEELENPLNVHRWRKLEASDPSTYELIQKIQRLQKQLISKTGEVIEKELLLQEKEKLYVELKHVLARQPGPEAAEQLQLYRHTLREKTKQLKILSSELNMYESQSQEYKYEIERLANELLNVKKKYLAQKRKEQQAKEKERSLAESEFPHLRSDVPRFTGGGFALSRPVPKVTA", "length": 875, "header": "tr|A0A8V0ZJU1-1|A0A8V0ZJU1_CHICK Isoform 1 of Cilia and flagella associated protein 58 OS=Gallus gallus OX=9031 GN=CFAP58 PE=4 SV=1 CANONICAL=A0A8V0ZJU1-1" }, "locus": { "chromosome": "6", "start_pos": 25128912, "end_pos": 25074442, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052021.1", "url": "https://www.ensembl.org/id/ENSGALT00010052021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031052.1", "url": "https://www.ensembl.org/id/ENSGALP00010031052.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A096MJJ4-1", "protein_name": "Cilia and flagella associated protein 58", "gene_name": "Cfap58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEEKPDKIAPEETAFEEIEKDFQEVLSELSGDKSLEKFRVEYEKLHTIMKKSYENEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLIEQGSGLSMDQDSNIRDLLKFKEEVTRERDQLLTEVVKLRENLAQITEKQQAAERAKEEAEHAISQFQQEIQHRQNEASRESRKKEKLEKELKQIQLDMDGRQSEIKAMQQYMHKSKEELQRLEQQLKEQKILNERAAKEVEQFQLRNMKLQQENEQHTLTCEQLSQENQQKALELKAKEDEIHQMRLDLGKLNKIREQIHKKLRLIDDQKIEVEQQKETLKNQILGLEREVESSKKQAELDKKAMEELLRERDILNKNMLKAVSATQKQVDLVKLHEQAKRNLEEEIQNYKDEAQKQRKIIFQLEKERDRYINEASDLTQRVLANMEDIKVREIQIFDYRKKIAESETKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITEMKRKLKIMTHQVDQLKEEISAKEAALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEVEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGETQYNQRVEDMRILKLEIKKLRREKGILARSVANVEELRQELYHMQREFLKERTRCRALEEELENPMNVHRWRKLEASDPSTFELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYVELKHILARQPGPEAAEQLQIYRYTLREKTKQLKVLSSELNMYESQSQEYKYEIERLSNELVTLKKKYLAQKRKELVQKNKDRISINNIFSDPKQSVPRFTGGGFPLNQPHKVKL", "length": 873 }, "evidence": [ { "id": "A0A8V0ZJU1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJU1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B2RW38-1", "protein_name": "Cilia- and flagella-associated protein 58", "gene_name": "Cfap58", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEDKAEKVMPEETAFEEIEKDFQEVLSELSGDKSLEKFRTEYEKLHSIMKKSYENEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQDSNIRDLLKFKEEVTKERDQLLSEVVKLRENLAQTIEKQQAAEHAKEEAEMAISQFQQEIQHRQNEASRESRKKEKLEKELRQIQTDMDGRQAEIKAMQQYMHKSKEELQRLEQQLKEQKILNERAAKEVEQFQMRNAKLQQENDQHTLTCEQLSQENQQKALELKAKEDEIHQMRLDLGKLNKIREQIHKKLHQLDDQKAEVEQQKDTLKNQILGLEREVESSKKQAELDKKAMEELLRERDILNKNMLKAVSATQKQVDLVKLHEQAKKNLEEEIQNYKDEAQKQRKIIFQLEKERDRYINEASDLTQRVLANMEDIKVREIQIFDYRKKIAESETKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITEMKRKLKIMTHQVDQLKEEISAKEAALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEVEERKLLRIIAEADGERVRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGETQYNQRVEDMRILKLEIKKLRREKGILARSVANVEELRQELYHMQREFLKERTRCRALEEELENPMNVHRWRKLEASDPSTFELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYVELKHILARQPGPEAAEQLQIYRHTLREKTKQLKVLSSELNMYESQSQEYKYEIERLGNELMSLKKKYLAQKRKELVLKNKDRMSMNNIFSETKKSVPRFTGGGFPLHQATKVKF", "length": 873 }, "evidence": [ { "id": "A0A8V0ZJU1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJU1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1QGB9-1", "protein_name": "Cilia- and flagella-associated protein 58", "gene_name": "cfap58", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNKEERQTTTMETDDSTLETMEIGFQEVLNELSGDEKFDKFRVEYEKVTKALRKSHENEKRLMAKCRELNAEIVSNSVKLSTAMKLVDEDQASINTLKQEIDKAWKMVEASHEKELQAKETIKKHKEEIANLNNLVEKGAGVSGGQEYSVGDLLKIKEELTEQRDKLLSEVVTLRENLTKATGAQQEIEAEKNKAMDMIAQLQQEIQVRQNEVHRETRRKEKLEKEVKQFQTDLESKQSEIKLLTQQSQRLQDDQQKLEQLLQEHKIINEKSSKEMEQLQHRNTKLQQDNEQNSINLEQLSQQNQQRASDLKMKEEEVTQLKQEITKLTRLREGAQRRLRQMEEQKAEVENQRETLKNQITGLEREMEASKNQIDADKKAIDELVRERDILNKNMIKAANETDKQQTLVKLHEQSKKTLEHEILNYRDEAQKQRKIIYQLEKERDRYINEASELTKKVLENIEDIKLKEMQIFEYKKRIAEAETKLKQQQNLYEDVRTERNLFSKNLIEAKDQNAEMRRKVKIVNHMFEQLKDEITAKEVALDKERQEFQRVERERENLKAELQKMKLQAQETKQLLAKQQAQEQELLKIIAEADAERIRQKKELDQVISERDLLGTQLVKRNDSLALLYEKVKIQQSILNKGEVHYNERLEDIRVLKIEIKKQRREKSILSKTVINVDDLRQEVFHMHRELMKERTRCRALEDELNNPLNVHRWRKLEASDPSSFELIQKIHSLQRRLISKTQEVVEKELLLQEKEKLYVELKHILARQPGPEAAEKLQVYQRTLREKTKQLKALTAELNMHESQAEGYKYEIERLVHELQEVKKKYFAQKRKDQENREKQRSLGPAGQPVIQPQRPDGPRFTGGGFSLKQHNRMTLQALEQQS", "length": 885 }, "evidence": [ { "id": "A0A8V0ZJU1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJU1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1S5N5-1", "protein_name": "Cilia and flagella associated protein 58", "gene_name": "CFAP58", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEEKSEKLVLEETAYEEIERDFQEVLNELSGDKSLERFRIEYEKLHAVMKKSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQDSNIRDLLKFKEEVTKERDQLLSEVVKLRESLAQITEQQQDTERSREEAEQAISQFQQEIQQRQNEASRETRKKEKLEKELKQIQTDMDTRQTEIKALQQYMQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKVLELKAKEEEVHQMRLDIGKLNKIREQIHKKLHQIEDQKGEVEQHKETLKNQILGLEREVEASKKQAELDKKAMDELLRERDVLNKNMLKAVNATQKQIDLVKLHEQAKRNLEEEIQNYREEAQKQRKIIFQLEKERDRYINEASDLTQKVLMNMEDIKVREMQIFDYRKKIAESETKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITEMKRKLKIMTHQVDQLKEEISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILKLEIKKLRREKGILARSVANVDELRQELFHTQREFLKERTRCRALEEELENPMNIHRWRKLEASDPSTFELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYVELKHILARQPGPEAAEQLQIYRHTLREKTKQLKVLSSELNMYESQSQEYKYEIEKLTNELLNLKKKYLAQKRKEYIQKNKDRISMDDAFSMAKPTGPRFTGGGFPLSKSSKMKS", "length": 873 }, "evidence": [ { "id": "A0A8V0ZJU1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJU1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5T655-1", "protein_name": "Cilia- and flagella-associated protein 58", "gene_name": "CFAP58", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEEKGGKQVLEESAFEEMERDFQGVLHELSGDKSLEKFRIEYERLHAVMKKSYDNEKRLMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQYNQRLEDMRILRLEIKKLRREKGILARSMANVEELRQEFFHMQRELLKERTRCRALEEELENPLNVHRWRKLEASDPNAYELIQKIHTLQKRLISKTEEVVEKELLLQEKEKLYMELKHVLARQPGPEAAEQLKLYRRTLHDKKQQLKVLSSELNMYEVQSKEYKYEVEKLTNELQNLKKKYLAQKRKEQLQKNKDTAPMDNTFLMVKPNGPGFTGGGFPLRSTKMTF", "length": 872 }, "evidence": [ { "id": "A0A8V0ZJU1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJU1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VB72-1", "protein_name": "Cilia- and flagella-associated protein 58 central coiled coil domain-containing protein", "gene_name": "Dmel\\CG5882", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKASGSEDEPLVPDDFDDDFYKELCDKIPEATKALRQKDTPNNADNVQRLLICGSRYKSDLRLEKERSQELRKEIESLEERLENAARVTKLDMATIEELRGVIEGAWKQKDAAQIREQSAQDEVLSLREKLDESEQMVAHLNEKRLAMSKRDDGKERERLNAEIADLNKRLHLQRTYATELDHTIEGLEAKNKELLKLLDETSSDACNLKRKSDALTKELSTMKTEESRYQEQISQMKSANEHLTKVKVRQNLQILSLKTNLEHLNTQHNAANNKLAKITVDLEYTVQERDKNKRALNQRINLLKVREDELIKVRQDNGKLAKSQEAIARKYAVLDEAKREVETLNIRLRTQLGTQDKELESMRRVVHHFEKNNENLTKERDSLRRELQAEHHQLEQSNAQHQEAQHEVRALKDTITTMDTKLKKLNEDANKLKKEKTKKLDEIQHWIDKLDALQNEMHLKENYEIELKRTISDLEAKCSKFQQQHDGLAAERQTLQRSVQLADEERQKLRDQLVNLQAHVEKLKAKIGYRDGEISRLQLQIDRMEKERRLLRNEIRHAQLGQQHTKAELLDKRKENDRHAKSLQEDEQKLARLRKDVDNLMNEKNAISAALTKRNEEFDRLKHSQENLQTVYDQTQRQCSQYQDDMRLMGVEIKNLRTERDVLRADRESAADLRQELLQMHRMLNQERIKARALQDEMVTPMNVHRWRLLSGKDPEKMDLLGRISILRKQLLQQNVAASEQERALNEAQQLYAALREFMLKLPSHKVRAELNSVKANLSAKDRKLKVLKAELSAREADEKSKKEKLEEMRVSLALTKTQLLEEKKHKQKLLEERQLLEQMHCYSAPAQLPRTLGAGFKMVSSLL", "length": 866 }, "evidence": [ { "id": "A0A8V0ZJU1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJU1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1" } ], "pmid": "" }, { "name": "protein localization to motile cilium", "id": "GO:0120229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1" } ], "pmid": "" }, { "name": "sperm mitochondrial sheath assembly", "id": "GO:0120317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120317", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU1" }, { "id": "PF21771", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21771" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cilia- and flagella-associated protein 58 central coiled coil", "eco_id": "ECO_0000259", "start_pos": 367, "end_pos": 671, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJB5-1", "uniprot_ac": "A0A8V0ZJB5", "uniprot_id": "A0A8V0ZJB5_CHICK", "mass": { "chemical_mass": 88680.0, "monoisotopic_mass": 88680.0 }, "refseq": {}, "gene_names": [ { "name": "GPAT2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5" } ] } ], "protein_names": [ { "name": "Glycerol-3-phosphate acyltransferase 2, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPAT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZJB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCS0", "url": "https://www.orthodb.org/?gene=A0A8V0ZCS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD99", "url": "https://www.orthodb.org/?gene=A0A8V0ZD99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJB5", "url": "https://www.orthodb.org/?gene=A0A8V0ZJB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12563", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12563", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12563:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12563:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483166", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-75109", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75109", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZCS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAWFSDSGQRVEVFIPSRRWFRPLMGRCCQACTPRSWVSPGWAEGCCLLQPKPTMTPSLCFQDGFYHTRLSSLGFRSATWVTEEDTRYRGWLVRRICCVLAVGSWKVLTNTPGDLLERVCSNKRVQDVAASQACGCRGDSKFQQQCKEKVLGILAGIQAPLCLPMLRLCCWALLRFLSCLFFSVQLHRGQLDMVLRAVRRKPGVPLVFLSTHKSQLDGLLLSFLLFSQGLGVPRVTVGNLTCSPRLRALLGCLGAVFLPTRVEQALSDQDGELPVAVLASYVEEVLRSRQPLVVFLEEPSAPWHLSGPARAWLAPLYRAVRDGAVPDILLVPVGIAYDRTPDRFCRDGAEPSAQPLGLRACLWAACRALCRCFGCARVDLAQPFSLQEFVAKSLICQSSMGKPLEELLPTILGMLSSQPDYSRADGPEHRMTTSSEAEEEMMVTKLGLHALSDAIACSAVTAVGITSALLLHKHRKCVRLSQLMADFAWLLEETLLRQHDVSFSGQLRALVLHSLAMLRAHLTLYHLAPLGDVLVVVKDSAETQWELSCHSTQIVPIFASEAVGACAIRALLLELLPFVGEAPCPSSITFSEDELHHKILTLLQLLPPSLLGLKPCQPLDCQSQDILDKLTLCGLLEAEEEGERYLCDVSSRRCRTPHWTNLDFSDSDTDSDDNHCKRCFRICEPKDSPGFLLFFCHLLSPVLATYVRAVAFLEQHSWPQPEAMCARALQQFLAEENGLEHPMWSLVLSTLQSFKNIGVLKERPSPSGPLLHLTQPFCSSEGRRKLRAFLEQFMQL", "length": 797, "header": "tr|A0A8V0ZJB5-1|A0A8V0ZJB5_CHICK Isoform 1 of Glycerol-3-phosphate acyltransferase 2, mitochondrial OS=Gallus gallus OX=9031 GN=GPAT2 PE=4 SV=1 CANONICAL=A0A8V0ZJB5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5/entry#A0A8V0ZCS0-1", "sequence": { "sequence": "MKAWFSDSGQRVEVFIPSRRWFRPLMGRCCQACTPRSWDGFYHTRLSSLGFRSATWVTEEDTRYRGWLVRRICCVLAVGSWKVLTNTPGDLLERVCSNKRVQDVAASQACGCRGDSKFQQQCKEKVLGILAGIQAPLCLPMLRLCCWALLRFLSCLFFSVQLHRGQLDMVLRAVRRKPGVPLVFLSTHKSQLDGLLLSFLLFSQGLGVPRVTVGNLTCSPRLRALLGCLGAVFLPTRVEQALSDQDGELPVAVLASYVEEVLRSRQPLVVFLEEPSAPWHLSGPARAWLAPLYRAVRDGAVPDILLVPVGIAYDRTPDRFCRDGAEPSAQPLGLRACLWAACRALCRCFGCARVDLAQPFSLQEFVAKSLICQSSMGKPLEELLPTILGMLSSQPDYSRADGPEHRMTTSSEAEEEMMVTKLGLHALSDAIACSAVTAVGITSALLLHKHRKCVRLSQLMADFAWLLEETLLRQHDVSFSGQLRALVLHSLAMLRAHLTLYHLAPLGDVLVVVKDSAETQWELSCHSTQIVPIFASEAVGACAIRALLLELLPFVGEAPCPSSITFSEDELHHKILTLLQLLPPSLLGLKPCQPLDCQSQDILDKLTLCGLLEAEEEGERYLCDVSSRRCRTPHWTNLDFSDSDTDSDDNHCKRCFRICEPKDSPGFLLFFCHLLSPVLATYVRAVAFLEQHSWPQPEHPMWSLVLSTLQSFKNIGVLKERPSPSGPLLHLTQPFCSSEGRRKLRAFLEQFMQL", "length": 754, "header": "tr|A0A8V0ZCS0-1|A0A8V0ZJB5_CHICK Computationally mapped isoform of Glycerol-3-phosphate acyltransferase 2, mitochondrial OS=Gallus gallus OX=9031 GN=GPAT2 PE=4 SV=1 CANONICAL=A0A8V0ZJB5-1" }, "locus": { "chromosome": "22", "start_pos": 4635652, "end_pos": 4629042, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048605.1", "url": "https://www.ensembl.org/id/ENSGALT00010048605.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028696.1", "url": "https://www.ensembl.org/id/ENSGALP00010028696.1" } ] } }, { "isoform_ac": "A0A8V0ZD99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5/entry#A0A8V0ZD99-1", "sequence": { "sequence": "MKAWFSDSGQRVEVFIPSRRWFRPLMGRCCQACTPRSWDGFYHTRLSSLGFRSATWVTEEDTRYRGWLVRRICCVLAVGSWKVLTNTPGDLLERVCSNKRVQDVAASQACGCRGDSKFQQQCKEKVLGILAGIQAPLCLPMLRLCCWALLRFLSCLFFSVQLHRGQLDMVLRAVRRKPGVPLVFLSTHKSQLDGLLLSFLLFSQGLGVPRVTVGNLTCSPRLRALLGCLGAVFLPTRVEQALSDQDGELPVAVLASYVEEVLRSRQPLVVFLEEPSAPWHLSGPARAWLAPLYRAVRDGAVPDILLVPVGIAYDRTPDRFCRDGAEPSAQPLGLRACLWAACRALCRCFGCARVDLAQPFSLQEFVAKSLICQSSMGKPLEELLPTILGMLSSQPDYSRADGPEHRMTTSSEAEEEMMVTKLGLHALSDAIACSAVTAVGITSALLLHKHRKLSPLFPQCVRLSQLMADFAWLLEETLLRQHDVSFSGQLRALVLHSLAMLRAHLTLYHLAPLGDVLVVVKDSAETQWELSCHSTQIVPIFASEAVGACAIRALLLELLPFVGEAPCPSSITFSEDELHHKILTLLQLLPPSLLGLKPCQPLDCQSQDILDKLTLCGLLEAEEEGERYLCDVSSRRCRTPHWTNLDFSDSDTDSDDNHCKRCFRICEPKDSPGFLLFFCHLLSPVLATYVRAVAFLEQHSWPQPEAMCARALQQFLAEENGLEHPMWSLVLSTLQSFKNIGVLKERPSPSGPLLHLTQPFCSSEGRRKLRAFLEQFMQL", "length": 779, "header": "tr|A0A8V0ZD99-1|A0A8V0ZJB5_CHICK Computationally mapped isoform of Glycerol-3-phosphate acyltransferase 2, mitochondrial OS=Gallus gallus OX=9031 GN=GPAT2 PE=4 SV=1 CANONICAL=A0A8V0ZJB5-1" }, "locus": { "chromosome": "22", "start_pos": 4635652, "end_pos": 4629042, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048599.1", "url": "https://www.ensembl.org/id/ENSGALT00010048599.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028690.1", "url": "https://www.ensembl.org/id/ENSGALP00010028690.1" } ] } }, { "isoform_ac": "A0A8V0ZJB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5/entry#A0A8V0ZJB5-1", "sequence": { "sequence": "MKAWFSDSGQRVEVFIPSRRWFRPLMGRCCQACTPRSWVSPGWAEGCCLLQPKPTMTPSLCFQDGFYHTRLSSLGFRSATWVTEEDTRYRGWLVRRICCVLAVGSWKVLTNTPGDLLERVCSNKRVQDVAASQACGCRGDSKFQQQCKEKVLGILAGIQAPLCLPMLRLCCWALLRFLSCLFFSVQLHRGQLDMVLRAVRRKPGVPLVFLSTHKSQLDGLLLSFLLFSQGLGVPRVTVGNLTCSPRLRALLGCLGAVFLPTRVEQALSDQDGELPVAVLASYVEEVLRSRQPLVVFLEEPSAPWHLSGPARAWLAPLYRAVRDGAVPDILLVPVGIAYDRTPDRFCRDGAEPSAQPLGLRACLWAACRALCRCFGCARVDLAQPFSLQEFVAKSLICQSSMGKPLEELLPTILGMLSSQPDYSRADGPEHRMTTSSEAEEEMMVTKLGLHALSDAIACSAVTAVGITSALLLHKHRKCVRLSQLMADFAWLLEETLLRQHDVSFSGQLRALVLHSLAMLRAHLTLYHLAPLGDVLVVVKDSAETQWELSCHSTQIVPIFASEAVGACAIRALLLELLPFVGEAPCPSSITFSEDELHHKILTLLQLLPPSLLGLKPCQPLDCQSQDILDKLTLCGLLEAEEEGERYLCDVSSRRCRTPHWTNLDFSDSDTDSDDNHCKRCFRICEPKDSPGFLLFFCHLLSPVLATYVRAVAFLEQHSWPQPEAMCARALQQFLAEENGLEHPMWSLVLSTLQSFKNIGVLKERPSPSGPLLHLTQPFCSSEGRRKLRAFLEQFMQL", "length": 797, "header": "tr|A0A8V0ZJB5-1|A0A8V0ZJB5_CHICK Isoform 1 of Glycerol-3-phosphate acyltransferase 2, mitochondrial OS=Gallus gallus OX=9031 GN=GPAT2 PE=4 SV=1 CANONICAL=A0A8V0ZJB5-1" }, "locus": { "chromosome": "22", "start_pos": 4635652, "end_pos": 4629042, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048602.1", "url": "https://www.ensembl.org/id/ENSGALT00010048602.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028693.1", "url": "https://www.ensembl.org/id/ENSGALP00010028693.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 237, "start_aa": "Thr", "end_pos": 237, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr237", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-1483166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483166", "resource": "Reactome", "description": "Synthesis of PA" }, { "id": "R-GGA-75109", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75109", "resource": "Reactome", "description": "Triglyceride biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5" } ], "pmid": "" }, { "name": "glycerophospholipid metabolic process", "id": "GO:0006650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5" } ], "pmid": "" }, { "name": "triglyceride biosynthetic process", "id": "GO:0019432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019432", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "O-acyltransferase activity", "id": "GO:0008374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5" } ], "pmid": "" }, { "name": "glycerol-3-phosphate O-acyltransferase activity", "id": "GO:0004366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004366", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB5" }, { "id": "SM00563", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00563" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phospholipid/glycerol acyltransferase", "eco_id": "ECO_0000259", "start_pos": 207, "end_pos": 339, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 237 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 240, "end_pos": 242 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZK98-1", "uniprot_ac": "A0A8V0ZK98", "uniprot_id": "A0A8V0ZK98_CHICK", "mass": { "chemical_mass": 174929.0, "monoisotopic_mass": 174929.0 }, "refseq": {}, "gene_names": [ { "name": "PLEKHH2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK98" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain-containing family H member 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK98/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK98#function" }, { "database": "UniProtKB", "id": "ARBA00054898", "url": "https://www.uniprot.org/uniprotkb/ARBA00054898#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK98" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK98", "locus": { "chromosome": "3", "start_pos": 24881235, "end_pos": 24828433, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020324", "url": "https://www.ensembl.org/id/ENSGALG00010020324" } ] } } ], "crossref": [ { "id": "cd13206", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13206", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13282", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13282", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17179", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17179", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCT1", "url": "https://www.orthodb.org/?gene=A0A8V0ZCT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK98", "url": "https://www.orthodb.org/?gene=A0A8V0ZK98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22903:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22903:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00784", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00784", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK98", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTQEHVHLLVRPCYDCSAQRADTQRHKPMQEPFIATVTAPAPLTAQLQRLGLINMADLSEPEGTVNWKERCLTLESQLMKFRLQASKIRELLAEKMQQLERQVIDADRQAERAFQQVQVMEEKLKAANVQTSESENRLYKRCQDLETLIQDKNDIIQKLEQQLEEQKQIRLQEAKIIEEKAAKIKEWVTVKLHELEVENQNLRLINQKQIKEMRTVQSKLQEATGKKSVTSTQKPGECQRLSSLTFGCFSNRARSPQPSPKFEEISKSSSKELDYAESKNTLEKDILETTSAGSAHESNKGQKSLQQSSSGSEQNKNVRTSRSSKDVDSDMSKNSCTTGSDWSSDEDGGDNKGLKSRCASTLSSHTSEENARYSRVGSEMYLTASDDSSSLFEEESLGVQRTQHKKLYSWQQGSQRKGQNNTGGRCNSDFTNMKKDLDSSSDELNKKFQSQRLDYSSSSSEANTPSPILTPALAHKHAIRATSADSQCTTPSDSPSNLPPPKLRTPNVFSINSSLAKKYLSQPQLSSDRMFGRNRNAISMIRPWRPQETDIDQVDGEDTAILEKMEIGCDEGVFTYDCTEAQDAEAQEPCDMTKKVASNKPPTPPLHRFPSWESRIYAVAKSGLRMSEAFTTESLNKSAASLTSYSISGLYTSLIYKNMTTPVYTTLKGKATQISNSPFIDESSGSEEEESSRSSSRTSESDSRCRSGPGSPRAMKRGVSLSSVTSDSDYAIPPDAYSVDTDYSEPEQKLPKTSSSSSDNGKNEPLEKSGYLLKMSGKVKTWKRRWFVLKGGELLYYKSPSDVIRKPQGQIELNASSHIERGDGKQTIQLTTEKRTYYLTADSPNILEEWIKVLQNVLKIQAASPLFIQPEIKPTMKGLLTKVKHGYSKRVWCTLVGKTLYYFRNQEDKFPLGQIKLFEAKVEEVDRSCDSDEDYEASGRSLLSTHYTVVIHPKDQGPTYLLIGSKHEKDTWLYHLTVAAGSTSVNVGSEFEQLICKLLNVEGDTTSQIWRHPTLCHSKEGITCPLTTLPSEALQTEAIKLFKTCQLFINAAVDSPAIDYHVSLAQSALQICLTHPELQNEICCQLIKQTRRRHPQNQTGPIQGLQLLALCIGLFLPQHPFLWLLKLHLKKNADSRTEFGKYAIYCQRCVERTQQNGDREARPSRMEILSTLLRNPYHHSLPFSIPVHFMNGIYQVVGFDASTTVDEFLNTLNQDTGMRKPAQSGFALFSDDPSGKDIEHCLQGNIKICDIISKWEQASKEQHPGKCEGTRTVRLTYKNRLYFSVQVHGETDREKLLLVYQTNDQIVNGLFPVNKELAMELSALLAQVEIGDFERPFSTPAGQVTSQSKSNQTLKQVLERFYPKRYRLGCSEEQLRQLCQRLSTRWMALRGHSAADCVRIYLTVARKWSFFGAKLFAAKPLATSSLEKSFIWFAVHEDGISILDYSTMRLTVTYTYKSLMTFGGYQDDFMLVVNDAQTKDKATEKLLFAMTKPKILEITLLIASYINNFHQQKGAAHHLSAPALLTPQSGQKLKEMGSQPLLTNNRPTKCPTLL", "length": 1554, "header": "tr|A0A8V0ZK98-1|A0A8V0ZK98_CHICK Isoform 1 of Pleckstrin homology domain-containing family H member 2 OS=Gallus gallus OX=9031 GN=PLEKHH2 PE=4 SV=1 CANONICAL=A0A8V0ZK98-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK98/entry#A0A8V0ZCT1-1", "sequence": { "sequence": "MADLSEPEGTVNWKERCLTLESQLMKFRLQASKIRELLAEKMQQLERQVIDADRQAERAFQQVQVMEEKLKAANVQTSESENRLYKRCQDLETLIQDKNDIIQKLEQQLEEQKQIRLQEAKIIEEKAAKIKEWVTVKLHELEVENQNLRLINQKQIKEMRTVQSKLQEATGKKSVTSTQKPGECQRLSSLTFGCFSNRARSPQPSPKFEEISKSSSKELDYAESKNTLEKDILETTSAGSAHESNKGQKSLQQSSSGSEQNKNVRTSRSSKDVDSDMSKNSCTTGSDWSSDEDGGDNKGLKSRCASTLSSHTSEENARYSRVGSEMYLTASDDSSSLFEEESLGVQRTQHKKLYSWQQGSQRKGQNNTGGRCNSDFTNMKKDLDSSSDELNKKFQSQRLDYSSSSSEANTPSPILTPALAHKHAIRATSADSQCTTPSDSPSNLPPPKLRTPNVFSINSSLAKKYLSQPQLSSDRMFGRNRNAISMIRPWRPQETDIDQVDGEDTAILEKMEIGCDEGVFTYDCTEAQDAEAQEPCDMTKKVASNKPPTPPLHRFPSWESRIYAVAKSGLRMSEAFTTESLNKSAASLTSYSISGLYTSLIYKNMTTPVYTTLKGKATQISNSPFIDESSGSEEEESSRSSSRTSESDSRCRSGPGSPRAMKRGVSLSSVTSDSDYAIPPDAYSVDTDYSEPEQKLPKTSSSSSDNGKNEPLEKSGYLLKMSGKVKTWKRRWFVLKGGELLYYKSPSDVIRKPQGQIELNASSHIERGDGKQTIQLTTEKRTYYLTADSPNILEEWIKVLQNVLKIQAASPLFIQPEIKPTMKGLLTKVKHGYSKRVWCTLVGKTLYYFRNQEDKFPLGQIKLFEAKVEEVDRSCDSDEDYEASGRSLLSTHYTVVIHPKDQGPTYLLIGSKHEKDTWLYHLTVAAGSTSVNVGSEFEQLICKLLNVEGDTTSQIWRHPTLCHSKEGITCPLTTLPSEALQTEAIKLFKTCQLFINAAVDSPAIDYHVSLAQSALQICLTHPELQNEICCQLIKQTRRRHPQNQTGPIQGLQLLALCIGLFLPQHPFLWLLKLHLKKNADSRTEFGKYAIYCQRCVERTQQNGDREARPSRMEILSTLLRNPYHHSLPFSIPVHFMNGIYQVVGFDASTTVDEFLNTLNQDTGMRKPAQSGFALFSDDPSGKDIEHCLQGNIKICDIISKWEQASKEQHPGKCEGTRTVRLTYKNRQLCQRLSTRWMALRGHSAADCVRIYLTVARKWSFFGAKLFAAKPLATSSLEKSFIWFAVHEDGISILDYSTMRLTVTYTYKSLMTFGGYQDDFMLVVNDAQTKDKATEKLLFAMTKPKILEITLLIASYINNFHQQKGAAHHLSAPALLTPQSGQKLKEMGSQPLLTNNRPTKCPTLL", "length": 1404, "header": "tr|A0A8V0ZCT1-1|A0A8V0ZK98_CHICK Computationally mapped isoform of Pleckstrin homology domain-containing family H member 2 OS=Gallus gallus OX=9031 GN=PLEKHH2 PE=4 SV=1 CANONICAL=A0A8V0ZK98-1" }, "locus": { "chromosome": "3", "start_pos": 24880314, "end_pos": 24832840, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049073.1", "url": "https://www.ensembl.org/id/ENSGALT00010049073.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029016.1", "url": "https://www.ensembl.org/id/ENSGALP00010029016.1" } ] } }, { "isoform_ac": "A0A8V0ZK98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK98/entry#A0A8V0ZK98-1", "sequence": { "sequence": "MTQEHVHLLVRPCYDCSAQRADTQRHKPMQEPFIATVTAPAPLTAQLQRLGLINMADLSEPEGTVNWKERCLTLESQLMKFRLQASKIRELLAEKMQQLERQVIDADRQAERAFQQVQVMEEKLKAANVQTSESENRLYKRCQDLETLIQDKNDIIQKLEQQLEEQKQIRLQEAKIIEEKAAKIKEWVTVKLHELEVENQNLRLINQKQIKEMRTVQSKLQEATGKKSVTSTQKPGECQRLSSLTFGCFSNRARSPQPSPKFEEISKSSSKELDYAESKNTLEKDILETTSAGSAHESNKGQKSLQQSSSGSEQNKNVRTSRSSKDVDSDMSKNSCTTGSDWSSDEDGGDNKGLKSRCASTLSSHTSEENARYSRVGSEMYLTASDDSSSLFEEESLGVQRTQHKKLYSWQQGSQRKGQNNTGGRCNSDFTNMKKDLDSSSDELNKKFQSQRLDYSSSSSEANTPSPILTPALAHKHAIRATSADSQCTTPSDSPSNLPPPKLRTPNVFSINSSLAKKYLSQPQLSSDRMFGRNRNAISMIRPWRPQETDIDQVDGEDTAILEKMEIGCDEGVFTYDCTEAQDAEAQEPCDMTKKVASNKPPTPPLHRFPSWESRIYAVAKSGLRMSEAFTTESLNKSAASLTSYSISGLYTSLIYKNMTTPVYTTLKGKATQISNSPFIDESSGSEEEESSRSSSRTSESDSRCRSGPGSPRAMKRGVSLSSVTSDSDYAIPPDAYSVDTDYSEPEQKLPKTSSSSSDNGKNEPLEKSGYLLKMSGKVKTWKRRWFVLKGGELLYYKSPSDVIRKPQGQIELNASSHIERGDGKQTIQLTTEKRTYYLTADSPNILEEWIKVLQNVLKIQAASPLFIQPEIKPTMKGLLTKVKHGYSKRVWCTLVGKTLYYFRNQEDKFPLGQIKLFEAKVEEVDRSCDSDEDYEASGRSLLSTHYTVVIHPKDQGPTYLLIGSKHEKDTWLYHLTVAAGSTSVNVGSEFEQLICKLLNVEGDTTSQIWRHPTLCHSKEGITCPLTTLPSEALQTEAIKLFKTCQLFINAAVDSPAIDYHVSLAQSALQICLTHPELQNEICCQLIKQTRRRHPQNQTGPIQGLQLLALCIGLFLPQHPFLWLLKLHLKKNADSRTEFGKYAIYCQRCVERTQQNGDREARPSRMEILSTLLRNPYHHSLPFSIPVHFMNGIYQVVGFDASTTVDEFLNTLNQDTGMRKPAQSGFALFSDDPSGKDIEHCLQGNIKICDIISKWEQASKEQHPGKCEGTRTVRLTYKNRLYFSVQVHGETDREKLLLVYQTNDQIVNGLFPVNKELAMELSALLAQVEIGDFERPFSTPAGQVTSQSKSNQTLKQVLERFYPKRYRLGCSEEQLRQLCQRLSTRWMALRGHSAADCVRIYLTVARKWSFFGAKLFAAKPLATSSLEKSFIWFAVHEDGISILDYSTMRLTVTYTYKSLMTFGGYQDDFMLVVNDAQTKDKATEKLLFAMTKPKILEITLLIASYINNFHQQKGAAHHLSAPALLTPQSGQKLKEMGSQPLLTNNRPTKCPTLL", 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-9639288", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZCU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARPCCYGSLPLPGQALRGGVRGRGSEGGGRGFRADMAAAERPEAEVEEAGHVFLLMKKDYRISRNVRLAWVLSRLHQVIWAVPEPELLKSENELDVLSILPNGWQPDEPVQPRPYLLVPSTRVTFLARQYRFVIELDLSPSTGIVDDSTGEIIFDEVFHALSRCLVGLLRPFRIPGSDIIYQPEIFVTIQAYSSIIGLQSHQVLFQGCQLDETKREAFLHQVYTQLCAFENKVAEMLQQQYEPKPQVDLSPLSQESPGDVQEPSGRKPSVSVVTADVGLVSMVRQGILALQLLPSNSSAGIIIITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGAYLSTCPELDPLSTDLNVYHKAFLLYSFLRTGESLNPEYYCVSQHRLFNEHLVSASSNPALAMRRKKHTEKEVHADLVSIVSVRLREGYSIREVNITKGGSQLEVKLVLLWKHNMRIEYLAVTPWPLDPSKRSTWVEVTMEGSYDILHDISCTMRKPITSLYRTTVIRRFWNTLQSINQTDQMLVHLQSFDTVPEHFTIPESTKNGVPLFYIPPGSTTPVLSLQHSGSDSSHSQFASYWKPILSMDANFWQRWLHMHRIVLLLEHDTPVPKHLHTPGNNGRYSTIQCRISHSALTSLLRDWSSFVLVEGYSYVKLMHSSEDPTPSSFYVVRIISKAPCMVLRLGFPIGTPAQARNKIVEELRDRILQLRFPHRVQSKEATPKAKRKMLGSSSPSKSPPVAGVQSALSDRPCLVVLHKPLEKLLIRYEKLPSDYRAPFILNLEHPPVSGPLTMVANRTASSTLASLSRYFYHQRWIWSVQSGLAPAVPITAVAQLLSTLTEVRLSEGFHFASSGDGIINMVLELPIQIDGSSGSSSGSSREKHTCVVQYILFPPHSTSTKDSFSTDDDNDTEVEAIEVDTELNLVTECWVEPQSGHVHSTAENWKHLHGLPYQKIPKALYPRDLACIATMLTFEYISQLCQNKEWVCPPSDTKATEDPDMGAGFRVHEIPFQFNLMKLLPRCQQVEMFFLMLTKENEEVTKDSSFVPNEMLLNLFHGCLQHDLSDREIPMADADHVAFMEQVLQRDRDGHQPPFTLPVIREETSKASGTLEQQDTSASYHHAGSNGTRDMTGSTSTLQSLGNTELPEDDVTLSDTTGPFPPQWRCYAKLVNPQHVFLTFLPATFSDVQKLMSCGLDKPPKDESQSGESTLRPVCAEQDRAEAEEGDAAVSLPTLSVTPVHEASHDSGEQSGPSRRDIHISFCRQNSQSELGECRRFRCPMYIYSCSLELLREQLVSPRTHRPPRDIFFRSQSLERPPAAAWLDHKHKELVSYCTLLQEHSHQCYVKGLFKSLQQSHSISSQDLLTAMDYCEELLQEIDITNFLLTVCSHVRSFRESHQHFHTHPKAASFQVGSIEQEEEQSSRERGVLVSESSAEMEDYSEQDSHNVASPPEEPKSSVGTSCCSEFPLSLLENGQPCQAHPDLHRIIQEKFLEIGSLHFKPVPSNPHYFFYCPPSAKKEEEASRDQADRKGSEDMEVSEAELAAEEGTVSGCCIATESDPELEVEYREKLEHEFPDTDSLSDSNTVNQDDDSFSVLGGDSLNEQEFLEQEMPPLFVHLTCSVKLRSQHSSMPVQSLPTCLGEVLGCLESCQGLTTIDLGDLCVTLDIFVLTLPLEIEVVNADILHNRCTSESSVSFTRSPGQPSSFRSDEDIMHNLDRLPSTGDERHPALSNLPGVHRQAIEATMNEIRWLLDDEIVSALRHSQVISTSILHRVATHIYNSKGRPSCHSEVVLLQFVFGPEHSLEKFKEEFRRMALPGYVINAEGNDYHYISISRLHSRRAAPNPSGTPCSQQQAGGSTGTALGQAGQEGSSEAEAESSELHRASCVLPEESQGLWGWPESEMRIVPDTGNPVGGGSHAQDEVTGEALSLEQTKVPGHDSLEEAVLETTIQSLPSSSSEKGNSEKSPLVTPSAASLADSVTQTREGSSKQRPSRVQSLVSSQGSMDSDHLGYDGGSSDSEYDEALMSDQEPKCPLMPDFWLIIKIEQDRVEVYYHTRLSVEKAASAEIEEQPGECQSLNQMVVKKISEICRVVNQRLLLQDLHDSHICNSLLVAESEEDIWKSETPYTYYRQRVMPTDDYSVEESYQPRDYLAATMQFMPGHFACDVVWSTLIHVHSRLKMGPNMGVSRAIQALRSVLNAFSVVNRKNMFVYQERATKSVFYLRLAETTNSGKGWEAESSISPGSRSLALTRSQEPIYTEDLTGSRSSLDTASCRSMDSARPVGQVDRHIQLMVHGVAPAGPEITDELVKVLRRRLDEATLDIITVMLVRNCKLTPADVEFIQPPGTPPTEVLQFTLPPSALPWLQAVAYYLRQNLLIFLHTPKYTDSNVEHHFKHYFSHSGGVPDQDLYLYNKPGGQGTGGKGIACIALTFVDETGSPTTLPHGERSGSPKVPIVDLLQDADFESLTAVSKHQPEAGTQHTEPCVLVRLDIWEKGNISLLQLSEKLRGALRHALCDAIMEFLVLPAPLCVEASCPLSAPDLEELSSAAGLRRTMSETKGLAMGTGGAGKSCPPPLHFTSAPLASPGEPVTPTSKLGRRSFWDMLSKAESSELGSPKTTDDIVLERPEEARTRRRHKTENVKQQLSQDRATATAELEQAQRRRVCQLEEGDVGTMHSLYSQTCQQWMAFMNHLGCPSVQQCSAEIVSRFLLSSILVEVVNLVTSLASDTTVKVFEKICCHRSTAFLPYKPGQSASPRPAAVRHFILLGRNFHQWRCSTEQDSSSEEEQPVPPAHRFRPHKGLQRFEAMEFSSAERGSDPSIVGRDLAPRQRFLFMEIVDKKLTLYTYNWSPDLGANLNCSLIRLLQWQNARSHIVHCLISQKMGLFHHHCFMDPPWHEDSKQEPNPFLNSTLEVDALIRSSCPPPSKEQGRLSSSARSLPSLHFHPDVVPFDEALRDVTTIKRIPHGPELGPFDPVARHGAQFLEIKSMERKELEKQMKIENLFVTWQQRSAQSNMPISLSDLETLKQSSRLVHYCATPLLFDPAFRQQIQADQQGKVEGKKRHRSNDSTASGRDRSHSCDSTESLPCKLKEEPWLQEMCNAFLQQYIQYLQSMGFILVQVRPPSPTTRSSTSRIRALAAVGVEGRGSFSYTKPKAEGSPKSTSPAVATYHLQRALPGGIVLMELAFQGYYFCVKQYALECSRIPMGQSVNSQLSMLFTEECDKVRDLMHVHSFSYDFHLRIVHQYLLGSHMTLRQGYHLTSFLEDFIAHHTDIPKFGRNHVFQGMLALPTNMITAHQLYNYIADHANTYHMKPLRMARPATGIDNKKGTPGTEQNEYALVSIWNSSGSYKDSEGLRHHDDFDVSLLVCHSAAPFEEQSEAERRMLRLRFYVIMTSQRELFPRLTADMRRFKKLPHLQREVLEPVVGPAAWEAAEPEPSLGRPQPAEREMWQDMEDSSEFYAGGKQVQVGPGLFYTSPLFPLLASEVASAQKQLSSMVQLAKCHCRRDNLWKRLFLLEPLASDKLKLGKLSLVELEELLDAVHGKSIADVDPQLGCFLTMTVSWYQSLIKVLLSRFPQSCRHFHNAETGTQYLVVLNQKFTDCFVLVFLDSHSGKTSLTVVFREPFPVQPQNSESPLPQLVSTYHHLESVINTACFNLWTGLL", "length": 3688, "header": "tr|A0A8V0ZJY5-1|A0A8V0ZJY5_CHICK Isoform 1 of Seizure threshold 2 homolog (mouse) OS=Gallus gallus OX=9031 GN=SZT2 PE=1 SV=1 CANONICAL=A0A8V0ZJY5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5/entry#A0A8V0ZCU2-1", "sequence": { "sequence": "MAAAERPEAEVEEAGHVFLLMKKDYRISRNVRLAWVLSRLHQVIWAVPEPELLKSENELDVLSILPNGWQPDEPVQPRPYLLVPSTRVTFLARQYRFVIELDLSPSTGIVDDSTGEIIFDEVFHALSRCLVGLLRPFRIPGSDIIYQPEIFVTIQAYSSIIGLQSHQVLFQGCQLDETKREAFLHQVYTQLCAFENKVAEMLQQQYEPKPQVDLSPLSQESPGDVQEPSGRKPSVSVVTADVGLVSMVRQGILALQLLPSNSSAGIIIITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGAYLSTCPELDPLSTDLNVYHKAFLLYSFLRTGESLNPEYYCVSQHRLFNEHLVSASSNPALAMRRKKHTEKEVHADLVSIVSVRLREGYSIREVNITKGGSQLEVKLVLLWKHNMRIEYLAVTPWPLDPSKRSTWVEVTMEGSYDILHDISCTMRKPITSLYRTTVIRRFWNTLQSINQTDQMLVHLQSFDTVPEHFTIPESTKNGVPLFYIPPGSTTPVLSLQHSGSDSSHSQFASYWKPILSMDANFWQRWLHMHRIVLLLEHDTPVPKHLHTPGNNGRYSTIQCRISHSALTSLLRDWSSFVLVEGYSYVKLMHSSEDPTPSSFYVVRIISKAPCMVLRLGFPIGTPAQARNKIVEELRDRILQLRFPHRVQSKEATPKAKRKMLGSSSPSKSPPVAGVQSALSDRPCLVVLHKPLEKLLIRYEKLPSDYRAPFILNLEHPPVSGPLTMVANRTASSTLASLSRYFYHQRWIWSVQSGLAPAVPITAVAQLLSTLTEVRLSEGFHFASSGDGIINMVLELPIQIDGSSGSSSGSSREKHTCVVQYILFPPHSTSTKDSFSTDDDNDTEVEAIEVDTELNLVTECWVEPQSGHVHSTAENWKHLHGLPYQKIPKALYPRDLACIATMLTFEYISQLCQNKEWVCPPSDTKATEDPDMGAGFRVHEIPFQFNLMKLLPRCQQVEMFFLMLTKENEEVTKDSSFVPNEMLLNLFHGCLQHDLSDREIPMADADHVAFMEQVLQRDRDGHQPPFTLPVIREETSKASGTLEQQDTSASYHHAGSNGTRDMTGSTSTLQSLGNTELPEDDVTLSDTTGPFPPQWRCYAKLVNPQHVFLTFLPATFSEASHDSGEQSGPSRRDIHISFCRQNSQSELGECRRFRCPMYIYSCSLELLREQLVSPRTHRPPRDIFFRSQSLERPPAAAWLDHKHKELVSYCTLLQEHSHQCYVKGLFKSLQQSHSISSQDLLTAMDYCEELLQEIDITNFLLTVCSHVRSFRESHQHFHTHPKAASFQVGSIEQEEEQSSRERGVLVSESSAEMEDYSEQDSHNVASPPEEPKSSVGTSCCSEFPLSLLENGQPCQAHPDLHRIIQEKFLEIGSLHFKPVPSNPHYFFYCPPSAKKEEEASRDQADRKGSEDMEVSEAELAAEEGTVSGCCIATESDPELEVEYREKLEHEFPDTDSLSDSNTVNQDDDSFSVLGGDSLNEQEFLEQEMPPLFVHLTCSVKLRSQHSSMPVQSLPTCLGEVLGCLESCQGLTTIDLGDLCVTLDIFVLTLPLEIEVVNADILHNRCTSESSVSFTRSPGQPSSFRSDEDIMHNLDRLPSTGDERHPALSNLPGVHRQAIEATMNEIRWLLDDEIVSALRHSQVISTSILHRVATHIYNSKGRPSCHSEVVLLQFVFGPEHSLEKFKEEFRRMALPGYVINAEGNDYHYISISRLHSRRAAPNPSGTPCSQQQAGGSTGTALGQAGQEGSSEAEAESSELHRASCVLPEESQGLWGWPESEMRIVPDTGNPVGGGSHAQDEVTGEALSLEQTKVPGHDSLEEAVLETTIQSLPSSSSEKGNSSSKQRPSRVQSLVSSQGSMDSDHLGYDGGSSDSEYDEALMSDQEPKCPLMPDFWLIIKIEQDRVEVYYHTRLSVEKAASAEIEEQPGECQSLNQMVVKKISEICRVVNQRLLLQDLHDSHICNSLLVAESEEDIWKSETPYTYYRQRVMPTDDYSVEESYQPRDYLAATMQFMPGHFACDVVWSTLIHVHSRLKMGPNMGVSRAIQALRSVLNAFSVVNRKNMFVYQERATKSVFYLRLAETTNSGKGWEAESSISPGSRSLALTRSQEPIYTEDLTGSRSSLDTASCRSMDSARPVGQVDRHIQLMVHGVAPAGPEITDELVKVLRRRLDEATLDIITVMLVRNCKLTPADVEFIQPPGTPPTEVLQFTLPPSALPWLQAVAYYLRQNLLIFLHTPKYTDSNVEHHFKHYFSHSGGVPDQDLYLYNKPGGQGTGGKGIACIALTFVDETGSPTTLPHGERSGSPKVPIVDLLQDADFESLTAVSKHQPEAGTQHTEPCVLVRLDIWEKGNISLLQLSEKLRGALRHALCDAIMEFLVLPAPLCVEASCPLSAPDLEELSSAAGLRRTMSETKGLAMGTGGAGKSCPPPLHFTSAPLASPGEPVTPTSKLGRRSFWDMLSKAESSELGSPKTTDDIVLERPEEARTRRRHKTENVKQQLSQDRATATAELEQAQRRRVCQLEEGDVGTMHSLYSQTCQQWMAFMNHLGCPSVQQCSAEIVSRFLLSSILVEVVNLVTSLASDTTVKVFEKICCHRSTAFLPYKPGQSASPRPAAVRHFILLGRNFHQWRCSTEQAHKGLQRFEAMEFSSAERGSDPSIVGRDLAPRQRFLFMEIVDKKLTLYTYNWSPDLGANLNCSLIRLLQWQNARSHIVHCLISQKMGLFHHHCFMDPPWHEDSKQPNPFLNSTLEVDALIRSSCPPPSKEQGRLSSSARSLPSLHFHPDVVPFDEALRDVTTIKRIPHGPELGPFDPVARHGAQFLEIKSMERKELEKQMKIENLFVTWQQRSAQSNMPISLSDLETLKQSSRLVHYCATPLLFDPAFRQQIQADQQGKVEGKKRHRSNDSTASGRDRSHSCDSTESLPCKLKEEPWLQEMCNAFLQQYIQYLQSMGFILVQVRPPSPTTRSTSRIRALAAVGVEGRGSFSYTKPKAEGSPKSTSPAVATYHLQRALPGGIVLMELAFQGYYFCVKQYALECSRIPMGQSVNSQLSMLFTEECDKVRDLMHVHSFSYDFHLRIVHQYLLGSHMTLRQGYHLTSFLEDFIAHHTDIPKFGRNHVFQGMLALPTNMITAHQLYNYIADHANTYHMKPLRMARPATGIDNKKGTPGTEQNEYALVSIWNSSGSYKDSEGLRHHDDFDVSLLVCHSAAPFEEQSEAERRMLRLRFYVIMTSQRELFPRLTADMRRFKKLPHLQREVLEPDMEDSSEFYAGGKQVQVGPGLFYTSPLFPLLASEVASAQKQLSSMVQLAKCHCRRDNLWKRLFLLEPLASDKLKLGKLSLVELEELLDAVHGKSIADVDPQLGCFLTMTVSWYQSLIKVLLSRFPQSCRHFHNAETGTQYLVVLNQKFTDCFVLVFLDSHSGKTSLTVVFREPFPVQPQNSESPLPQLVSTYHHLESVINTACFNLWTGLL", "length": 3526, "header": "tr|A0A8V0ZCU2-1|A0A8V0ZJY5_CHICK Computationally mapped isoform of Seizure threshold 2 homolog (mouse) OS=Gallus gallus OX=9031 GN=SZT2 PE=1 SV=1 CANONICAL=A0A8V0ZJY5-1" }, "locus": { "chromosome": "8", "start_pos": 19459695, "end_pos": 19406016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052076.1", "url": "https://www.ensembl.org/id/ENSGALT00010052076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031088.1", "url": "https://www.ensembl.org/id/ENSGALP00010031088.1" } ] } }, { "isoform_ac": "A0A8V0ZJY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5/entry#A0A8V0ZJY5-1", "sequence": { "sequence": "MAARPCCYGSLPLPGQALRGGVRGRGSEGGGRGFRADMAAAERPEAEVEEAGHVFLLMKKDYRISRNVRLAWVLSRLHQVIWAVPEPELLKSENELDVLSILPNGWQPDEPVQPRPYLLVPSTRVTFLARQYRFVIELDLSPSTGIVDDSTGEIIFDEVFHALSRCLVGLLRPFRIPGSDIIYQPEIFVTIQAYSSIIGLQSHQVLFQGCQLDETKREAFLHQVYTQLCAFENKVAEMLQQQYEPKPQVDLSPLSQESPGDVQEPSGRKPSVSVVTADVGLVSMVRQGILALQLLPSNSSAGIIIITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGAYLSTCPELDPLSTDLNVYHKAFLLYSFLRTGESLNPEYYCVSQHRLFNEHLVSASSNPALAMRRKKHTEKEVHADLVSIVSVRLREGYSIREVNITKGGSQLEVKLVLLWKHNMRIEYLAVTPWPLDPSKRSTWVEVTMEGSYDILHDISCTMRKPITSLYRTTVIRRFWNTLQSINQTDQMLVHLQSFDTVPEHFTIPESTKNGVPLFYIPPGSTTPVLSLQHSGSDSSHSQFASYWKPILSMDANFWQRWLHMHRIVLLLEHDTPVPKHLHTPGNNGRYSTIQCRISHSALTSLLRDWSSFVLVEGYSYVKLMHSSEDPTPSSFYVVRIISKAPCMVLRLGFPIGTPAQARNKIVEELRDRILQLRFPHRVQSKEATPKAKRKMLGSSSPSKSPPVAGVQSALSDRPCLVVLHKPLEKLLIRYEKLPSDYRAPFILNLEHPPVSGPLTMVANRTASSTLASLSRYFYHQRWIWSVQSGLAPAVPITAVAQLLSTLTEVRLSEGFHFASSGDGIINMVLELPIQIDGSSGSSSGSSREKHTCVVQYILFPPHSTSTKDSFSTDDDNDTEVEAIEVDTELNLVTECWVEPQSGHVHSTAENWKHLHGLPYQKIPKALYPRDLACIATMLTFEYISQLCQNKEWVCPPSDTKATEDPDMGAGFRVHEIPFQFNLMKLLPRCQQVEMFFLMLTKENEEVTKDSSFVPNEMLLNLFHGCLQHDLSDREIPMADADHVAFMEQVLQRDRDGHQPPFTLPVIREETSKASGTLEQQDTSASYHHAGSNGTRDMTGSTSTLQSLGNTELPEDDVTLSDTTGPFPPQWRCYAKLVNPQHVFLTFLPATFSDVQKLMSCGLDKPPKDESQSGESTLRPVCAEQDRAEAEEGDAAVSLPTLSVTPVHEASHDSGEQSGPSRRDIHISFCRQNSQSELGECRRFRCPMYIYSCSLELLREQLVSPRTHRPPRDIFFRSQSLERPPAAAWLDHKHKELVSYCTLLQEHSHQCYVKGLFKSLQQSHSISSQDLLTAMDYCEELLQEIDITNFLLTVCSHVRSFRESHQHFHTHPKAASFQVGSIEQEEEQSSRERGVLVSESSAEMEDYSEQDSHNVASPPEEPKSSVGTSCCSEFPLSLLENGQPCQAHPDLHRIIQEKFLEIGSLHFKPVPSNPHYFFYCPPSAKKEEEASRDQADRKGSEDMEVSEAELAAEEGTVSGCCIATESDPELEVEYREKLEHEFPDTDSLSDSNTVNQDDDSFSVLGGDSLNEQEFLEQEMPPLFVHLTCSVKLRSQHSSMPVQSLPTCLGEVLGCLESCQGLTTIDLGDLCVTLDIFVLTLPLEIEVVNADILHNRCTSESSVSFTRSPGQPSSFRSDEDIMHNLDRLPSTGDERHPALSNLPGVHRQAIEATMNEIRWLLDDEIVSALRHSQVISTSILHRVATHIYNSKGRPSCHSEVVLLQFVFGPEHSLEKFKEEFRRMALPGYVINAEGNDYHYISISRLHSRRAAPNPSGTPCSQQQAGGSTGTALGQAGQEGSSEAEAESSELHRASCVLPEESQGLWGWPESEMRIVPDTGNPVGGGSHAQDEVTGEALSLEQTKVPGHDSLEEAVLETTIQSLPSSSSEKGNSEKSPLVTPSAASLADSVTQTREGSSKQRPSRVQSLVSSQGSMDSDHLGYDGGSSDSEYDEALMSDQEPKCPLMPDFWLIIKIEQDRVEVYYHTRLSVEKAASAEIEEQPGECQSLNQMVVKKISEICRVVNQRLLLQDLHDSHICNSLLVAESEEDIWKSETPYTYYRQRVMPTDDYSVEESYQPRDYLAATMQFMPGHFACDVVWSTLIHVHSRLKMGPNMGVSRAIQALRSVLNAFSVVNRKNMFVYQERATKSVFYLRLAETTNSGKGWEAESSISPGSRSLALTRSQEPIYTEDLTGSRSSLDTASCRSMDSARPVGQVDRHIQLMVHGVAPAGPEITDELVKVLRRRLDEATLDIITVMLVRNCKLTPADVEFIQPPGTPPTEVLQFTLPPSALPWLQAVAYYLRQNLLIFLHTPKYTDSNVEHHFKHYFSHSGGVPDQDLYLYNKPGGQGTGGKGIACIALTFVDETGSPTTLPHGERSGSPKVPIVDLLQDADFESLTAVSKHQPEAGTQHTEPCVLVRLDIWEKGNISLLQLSEKLRGALRHALCDAIMEFLVLPAPLCVEASCPLSAPDLEELSSAAGLRRTMSETKGLAMGTGGAGKSCPPPLHFTSAPLASPGEPVTPTSKLGRRSFWDMLSKAESSELGSPKTTDDIVLERPEEARTRRRHKTENVKQQLSQDRATATAELEQAQRRRVCQLEEGDVGTMHSLYSQTCQQWMAFMNHLGCPSVQQCSAEIVSRFLLSSILVEVVNLVTSLASDTTVKVFEKICCHRSTAFLPYKPGQSASPRPAAVRHFILLGRNFHQWRCSTEQDSSSEEEQPVPPAHRFRPHKGLQRFEAMEFSSAERGSDPSIVGRDLAPRQRFLFMEIVDKKLTLYTYNWSPDLGANLNCSLIRLLQWQNARSHIVHCLISQKMGLFHHHCFMDPPWHEDSKQEPNPFLNSTLEVDALIRSSCPPPSKEQGRLSSSARSLPSLHFHPDVVPFDEALRDVTTIKRIPHGPELGPFDPVARHGAQFLEIKSMERKELEKQMKIENLFVTWQQRSAQSNMPISLSDLETLKQSSRLVHYCATPLLFDPAFRQQIQADQQGKVEGKKRHRSNDSTASGRDRSHSCDSTESLPCKLKEEPWLQEMCNAFLQQYIQYLQSMGFILVQVRPPSPTTRSSTSRIRALAAVGVEGRGSFSYTKPKAEGSPKSTSPAVATYHLQRALPGGIVLMELAFQGYYFCVKQYALECSRIPMGQSVNSQLSMLFTEECDKVRDLMHVHSFSYDFHLRIVHQYLLGSHMTLRQGYHLTSFLEDFIAHHTDIPKFGRNHVFQGMLALPTNMITAHQLYNYIADHANTYHMKPLRMARPATGIDNKKGTPGTEQNEYALVSIWNSSGSYKDSEGLRHHDDFDVSLLVCHSAAPFEEQSEAERRMLRLRFYVIMTSQRELFPRLTADMRRFKKLPHLQREVLEPVVGPAAWEAAEPEPSLGRPQPAEREMWQDMEDSSEFYAGGKQVQVGPGLFYTSPLFPLLASEVASAQKQLSSMVQLAKCHCRRDNLWKRLFLLEPLASDKLKLGKLSLVELEELLDAVHGKSIADVDPQLGCFLTMTVSWYQSLIKVLLSRFPQSCRHFHNAETGTQYLVVLNQKFTDCFVLVFLDSHSGKTSLTVVFREPFPVQPQNSESPLPQLVSTYHHLESVINTACFNLWTGLL", "length": 3688, "header": "tr|A0A8V0ZJY5-1|A0A8V0ZJY5_CHICK Isoform 1 of Seizure threshold 2 homolog (mouse) OS=Gallus gallus OX=9031 GN=SZT2 PE=1 SV=1 CANONICAL=A0A8V0ZJY5-1" }, "locus": { "chromosome": "8", "start_pos": 19459695, "end_pos": 19405905, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052085.1", "url": "https://www.ensembl.org/id/ENSGALT00010052085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031097.1", "url": "https://www.ensembl.org/id/ENSGALP00010031097.1" } ] } }, { "isoform_ac": "A0A8V0ZQQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5/entry#A0A8V0ZQQ9-1", "sequence": { "sequence": "MAAAERPEAEVEEAGHVFLLMKKDYRISRNVRLAWVLSRLHQVIWAVPEPELLKSENELDVLSILPNGWQPDEPVQPRPYLLVPSTRVTFLARQYRFVIELDLSPSTGIVDDSTGEIIFDEVFHALSRCLVGLLRPFRIPGSDIIYQPEIFVTIQAYSSIIGLQSHQVLFQGCQLDETKREAFLHQVYTQLCAFENKVAEMLQQQYEPKPQVDLSPLSQESPGDVQEPSGRKPSVSVVTADVGLVSMVRQGILALQLLPSNSSAGIIIITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGAYLSTCPELDPLSTDLNVYHKAFLLYSFLRTGESLNPEYYCVSQHRLFNEHLVSASSNPALAMRRKKHTEKEVHADLVSIVSVRLREGYSIREVNITKGGSQLEVKLVLLWKHNMRIEYLAVTPWPLDPSKRSTWVEVTMEGSYDILHDISCTMRKPITSLYRTTVIRRFWNTLQSINQTDQMLVHLQSFDTVPEHFTIPESTKNGVPLFYIPPGSTTPVLSLQHSGSDSSHSQFASYWKPILSMDANFWQRWLHMHRIVLLLEHDTPVPKHLHTPGNNGRYSTIQCRISHSALTSLLRDWSSFVLVEGYSYVKLMHSSEDPTPSSFYVVRIISKAPCMVLRLGFPIGTPAQARNKIVEELRDRILQLRFPHRVQSKEATPKAKRKMLGSSSPSKSPPVAGVQSALSDRPCLVVLHKPLEKLLIRYEKLPSDYRAPFILNLEHPPVSGPLTMVANRTASSTLASLSRYFYHQRWIWSVQSGLAPAVPITAVAQLLSTLTEVRLSEGFHFASSGDGIINMVLELPIQIDGSSGSSSGSSREKHTCVVQYILFPPHSTSTKDSFSTDDDNDTEVEAIEVDTELNLVTECWVEPQSGHVHSTAENWKHLHGLPYQKIPKALYPRDLACIATMLTFEYISQLCQNKEWVCPPSDTKATEDPDMGAGFRVHEIPFQFNLMKLLPRCQQVEMFFLMLTKENEEVTKDSSFVPNEMLLNLFHGCLQHDLSDREIPMADADHVAFMEQVLQRDRDGHQPPFTLPVIREETSKASGTLEQQDTSASYHHAGSNGTRDMTGSTSTLQSLGNTELPEDDVTLSDTTGPFPPQWRCYAKLVNPQHVFLTFLPATFSDVQKLMSCGLDKPPKDESQSGESTLRPVCAEQDRAEAEEGDAAVSLPTLSVTPVHEASHDSGEQSGPSRRDIHISFCRQNSQSELGECRRFRCPMYIYSCSLELLREQLVSPRTHRPPRDIFFRSQSLERPPAAAWLDHKHKELVSYCTLLQEHSHQCYVKGLFKSLQQSHSISSQDLLTAMDYCEELLQEIDITNFLLTVCSHVRSFRESHQHFHTHPKAASFQVGSIEQEEEQSSRERGVLVSESSAEMEDYSEQDSHNVASPPEEPKSSVGTSCCSEFPLSLLENGQPCQAHPDLHRIIQEKFLEIGSLHFKPVPSNPHYFFYCPPSAKKEEEASRDQADRKGSEDMEVSEAELAAEEGTVSGCCIATESDPELEVEYREKLEHEFPDTDSLSDSNTVNQDDDSFSVLGGDSLNEQEFLEQEMPPLFVHLTCSVKLRSQHSSMPVQSLPTCLGEVLGCLESCQGLTTIDLGDLCVTLDIFVLTLPLEIEVVNADILHNRCTSESSVSFTRSPGQPSSFRSDEDIMHNLDRLPSTGDERHPALSNLPGVHRQAIEATMNEIRWLLDDEIVSALRHSQVISTSILHRVATHIYNSKGRPSCHSEVVLLQFVFGPEHSLEKFKEEFRRMALPGYVINAEGNDYHYISISRLHSRRAAPNPSGTPCSQQQAGGSTGTALGQAGQEGSSEAEAESSELHRASCVLPEESQGLWGWPESEMRIVPDTGNPVGGGSHAQDEVTGEALSLEQTKVPGHDSLEEAVLETTIQSLPSSSSEKGNSEKSPLVTPSAASLADSVTQTREGSSKQRPSRVQSLVSSQGSMDSDHLGYDGGSSDSEYDEALMSDQEPKCPLMPDFWLIIKIEQDRVEVYYHTRSLSVEKAASAEIEEQPGECQSLNQMVVKKISEICRVVNQRLLLQDLHDSHICNSLLVAESEEDIWKSETPYTYYRQRVMPTDDYSVEESYQPRDYLAATMQFMPGHFACDVVWSTLIHVHSRLKMGPNMGVSRAIQALRSVLNAFSVVNRKNMFVYQERATKSVFYLRLAETTNSGKGWEAESSISPGSRSLALTRSQEPIYTEDLTGSRSSLDTASCRSMDSARPVGQVDRHIQLMVHGVAPAGPEITDELVKVLRRRLDEATLDIITVMLVRNCKLTPADVEFIQPPGTPPTEVLQFTLPPSALPWLQAVAYYLRQNLLIFLHTPKYTDSNVEHHFKHYFSHSGGVPDQDLYLYNKPGGQGTGGKGIACIALTFVDETGSPTTLPHGERSGSPKVPIVDLLQDADFESLTAVSKHQPEAGTQHTEPCVLVRLDIWEKGNISLLQLSEKLRGALRHALCDAIMEFLVLPAPLCVEASCPLSAPDLEELSSAAGLRRTMSETKGLAMGTGGAGKSCPPPLHFTSAPLASPGEPVTPTSKLGRRSFWDMLSKAESSELGSPKTTDDIVLERPEEARTRRRHKTENVKQQLSQDRATATAELEQAQRRRVCQLEEGDVGTMHSLYSQTCQQWMAFMNHLGCPSVQQCSAEIVSRFLLSSILVEVVNLVTSLASDTTVKVFEKICCHRSTAFLPYKPGQSASPRPAAVRHFILLGRNFHQWRCSTEQAHKGLQRFEAMEFSSAERGSDPSIVGRDLAPRQRFLFMEIVDKKLTLYTYNWSPDLGANLNCSLIRLLQWQNARSHIVHCLISQKMGLFHHHCFMDPPWHEDSKQEPNPFLNSTLEVDALIRSSCPPPSKEQGRLSSSARSLPSLHFHPDVVPFDEALRDVTTIKRIPHGPELGPFDPVARHGAQFLEIKSMERKELEKQMKIENLFVTWQQRSAQSNMPISLSDLETLKQSSRLVHYCATPLLFDPAFRQQIQADQQGKVEGKKRHRSNDSTASGRDRSHSCDSTESLPCKLKEEPWLQEMCNAFLQQYIQYLQSMGFILVQVRPPSPTTRSSTSRIRALAAVGVEGRGSFSYTKPKAEGSPKSTSPAVATYHLQRALPGGIVLMELAFQGYYFCVKQYALECSRIPMGQSVNSQLSMLFTEECDKVRDLMHVHSFSYDFHLRIVHQYLLGSHMTLRQGYHLTSFLEDFIAHHTDIPKFGRNHVFQGMLALPTNMITAHQLYNYIADHANTYHMKPLRMARPATGIDNKKGTPGTEQNEYALVSIWNSSGSYKDSEGLRHHDDFDVSLLVCHSAAPFEEQSEAERRMLRLRFYVIMTSQRELFPRLTADMRRFKKLPHLQREVLEPVVGPAAWEAAEPEPSLGRPQPAEREMWQDMEDSSEFYAGGKQVQVGPGLFYTSPLFPLLASEVASAQKQLSSMVQLAKCHCRRDNLWKRLFLLEPLASDKLKLGKLSLVELEELLDAVHGKSIADVDPQLGCFLTMTVSWYQSLIKVLLSRFPQSCRHFHNAETGTQYLVVLNQKFTDCFVLVFLDSHSGKTSLTVVFREPFPVQPQNSESPLPQLVSTYHHLESVINTACFNLWTGLL", "length": 3635, "header": "tr|A0A8V0ZQQ9-1|A0A8V0ZQQ9_CHICK Computationally mapped isoform of Seizure threshold 2 homolog (mouse) OS=Gallus gallus OX=9031 GN=SZT2 PE=1 SV=1 CANONICAL=A0A8V0ZJY5-1" }, "locus": { "chromosome": "8", "start_pos": 19459695, "end_pos": 19406016, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052045.1", "url": "https://www.ensembl.org/id/ENSGALT00010052045.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031069.1", "url": "https://www.ensembl.org/id/ENSGALP00010031069.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1995, "start_aa": "Thr", "end_pos": 1995, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1995", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 489, "start_aa": "Thr", "end_pos": 489, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr489", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 689, "start_aa": "Thr", "end_pos": 689, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr689", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424566", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424566", "resource": "KEGG Pathway" }, { "id": "R-GGA-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" } ], "orthologs": [ { "uniprot_canonical_ac": "A2A9C3-1", "protein_name": "KICSTOR complex protein SZT2", "gene_name": "Szt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLNHLHQTVQATPQELLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCINFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQREAFLQQVYEQLCLFEDKVATMLQQQYEPQGQAEDQSPESGESLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPETEPGNLGLTVYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAVAPWPLEPEGPRGTRVEVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGSSTPVLSLQHSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPLPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPSSFYMVRIISKTPCMVLRLGFPIGTPAQARHKIVSGLKEEILRLRFPHRVQSKEPTPKVKRKGLGGVGGSSPSKSPPTLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHRRWLWSVPSGLAPTLPLSATAQLLSVLTEVRLSEGFHFACSGEGIINMVLELPVQNEPLGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPENWKHLQDLTYSEIPQALHPRDAACIGSLLTFEYLIQLCQSKEWGPLPPEPRLSDGLDQRGDTCVHEIPFHFDLLGLLPQCQQLQMFFLLLSREPEGVPLAEGPCPTNDMVLCLLHSCLGQELSDREIPLTPADQAAFLNEVLRRSLRDPGPEGPPVGGHAVAKDRAGNSTQASGDSTLPSQSVVIPGVLRSSISAQPPQWHCYARLLGPQHVFLTFLPATFSDVQHLTAYGLESSFQEETKPKLGDWSGAPSLKDPGATGTKATESQVPTLSVTLASDSAQDSGEPSTPSCQDLAANSGRQAPQTEGADGPRTRCPVYIYSCSLEALREQMVGLQPPQAPRDLIFRAQDLDHPSSSSAWMEPRCKEAATHCALLQEHAQRCFVRGLFRSLQQAQSVTCQDLLTAVDACEELLQEIDITSFLLALCGHTWGLPHAPPSPGPLSPGPFSSSIEEGPEPRERAILVSESSIETEDLSEPEFQSSRVSGNLDPGPEISLTDVCQLRGEAHDALHSLIQEKFLEISRLHFRTVPSNPHYFFYCPPSSRREDEGPRDTVDRKISDLEFSEAELVGEEGDTSACCVVTESDPELEVEYRESREPDLGPAGLDSASLSDADTVNPDEDSFSILGGDSPTGPDSLMHDLPPLFLHLTCSVRLRGQHSSVPVCSLPTCLGQVLSSLEGPPIGGRVPLRDLSITLDVFVLTLPLEVELPPASDPQHHRSTSESSASFPRSPGQPSSLRSDDGLGPPLPPPEEERHPGLSSLAMPHRLAIESTMNEIRWLLEDEMVGALRRGGIPQSPALHRAAAHIHSSSGRPTCLRQAPPLSFVFGPERSLTQFKEEFRRLHLPGHVLLEDPDSGFFFVAAGQQPGVLHGEPPSAAWAWHNHEDRAEDAEGEVLTASPQVPGSLEDSEGTPLISLPSLSQGGSQPGPSRGLSLMSSQGSVDSDHLGYDGGSSGSDSEGPGETLGEKALFTLRTPPGPAPPQPSLPVLPGPSLPDFWLIVRILQDRVEVYAHARSLSREDGGPGAECRHLQQFLVRRVGEICREVNQRLLLQDLHDSHVCNSLLVAESEEDLWRSETPFHSRQRAVLPSDDFAADESCAPRGYLAATMQFVPGHFSCDVVWGTVIRVHSRLKMGPSMGVSRAIQALRSVLNAFSVVNRKNMFVYQERATKAVYYLRLLETSCSDRPWEGDTLPPSLALSRSQEPISSEDSVAPRSPLDMASSRSSDAVRPVGQVDRHIQLLVHGVGQAGPEITDELVRVLRRRLDEATLDIITVMLVRNCKLTPADVEFIQPPGSLPSEVLHLVLPPSCRPCLPALAWYLRQNLLTFLHSPKYTDSNSRNHFQHPLPAQGGLPDLDIYLYNKPGGQGTGGKGVACITLAFVEEGGTPISLASWPPSSPGPPDPLREEEFEQLTQVIRCPNTLDSCSAQDGSPRLRLDVWEKGNISIVQLEEKLRAAARQALADAIMELRLLPASLCTEDIPPGSLKSGPLDTKSPACRANTFPCTPVSGEPVTPPSKAGRRSFWDMLSKTEAGDLGSPKTTDDIVLDRPEDTRGRRRHKTENVRTPGGSERAPGPDSGAQRQRRRTTQLEEGEVGTLHPVFARVIQRWMGFMVQIGCASVSRSSTHMVSRFLLPSILSEFTTLVISMAGDTSVRVFEQHLGSEPDVFSPCSPGQLGPAPRPAAQRHLLLLGRNFAQWRRPTQQAAKAVQRFESGGDGSPGRSAPRQRLLLLEVTDKKLQLLTYNWAPDLGAALGRALIRLVQWQNARAHLISCLLSQKLGLFHHCGQLDFPMRDGKEPNPFLLPTMEVETLIRNASPPLSREQGRLSGSSRGGGPLSLDTFPFDEALRDITAARPSSTGGPAPRPPDPVTYHGQQFLEIKMTERKELERQMKMENLFVTWQQRSAPASMPISAGELETLKQSSRLVHYCATALLFDPAAWLHGPPETCAPSEGQRRPCPESGSGSREVPTSCESLDVPPPGAREEPWLKELSLAFLQQYVQYLQSIGFVLVPLRPPSPARSTSRLRAMAILGTEGRGSFSCPKAKAEGSPKSTSTPVTTYHLQRALPGGIILMELTFQGCYFCVKQFALECSRIPMGQAVNSQLSLLFTEECDKVRDLMHVHSFSYDFHLRLVHQHVLGAHLALRHGYHLTTFLQHFLAHHPDGPHFGRNHIYQGTLELPTPLIAAHQLYNYVADHASSYHMKPLRMARPGGPEHNEYALVSAWHSSGSYLDSEGLRHQDDFDVSLLVCHSAAPFEEQGEAERHVLRLQFFVVLTSQRELFPRLTADMRRFRKPSRLPLEPETPGSLVGSPREASGMMLAPGPAPLFPPLAAEVGMARARLAQLVRLAGGHCRRDTLWKRLFLLEPPGPDRLRLGGRLALAELEELLEAVHAKSIADIDPQLDCFLSMTVSWYQSLIKVLLSRFPQSCRHFQSPDLGTQYLVVLNQKFTDCFVLVFLDSHLGKTSLTVVFREPFPVQPQDSESPPAQLVSTYHHLESVINTACFTLWTRLL", "length": 3431 }, "evidence": [ { "id": "A0A8V0ZJY5", "url": "https://omabrowser.org/oma/group/A0A8V0ZJY5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZUQ8-1", "protein_name": "SZT2 subunit of KICSTOR complex", "gene_name": "Szt2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLNHLHQTVQAIPQESLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSRREAFLQQVYEQLCLFEEKVATMLQQQHEPQSQAEDQSPESGESLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAKAGSQLEVKLVLLWKHNMRIEYVAVAPWPLEPEGPRGTRVEVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQAFSSVPEHFTLPDSTKSGVPLFYIPPGSGTPVLSLQHSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPLPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPSSFYMVRIISKAPCMVLRLGFPIGTPAQARHKIVSGLQEEILRLRFPHRVQSKEPTPKVKRKGLGGVGGSSPSKSPPTLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHRRWLWSVPSGLAPTLPLSAIAQLLSVLTEVRLSEGFHFACSGEGIINMVLELPVQNDPLGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPESWKHLQDLTYSEIPQALHPRDAACIGSLLTFEYLIQLCQSKEWGPLPPEPQVSDGLDQRGDTCVHEIPFRFDLLGLLPQCQQLQMFFLLLSREPEGVPLTEGPCPTNDMVLCLLHSCLGQELSDREIPLTTADQTAFLNEVLRRSSLDPGPEGALVGGHAIPKDQAGNRTQATGDSTLPTQSVGIPGIPRSSISAQPPQWHCYARLLSPQHVFLTFLPATFSDVQHLTAYGLVGSSQEETKPKLGDWSGAPSLKDLGAAGTRAPKSQVPILSVTLASDSTQNPGEPSPPSCRDFPANSGRQAPQTEGADGPRTRCPVYIYSCSLEALREQMVGLQPPQAPRDLIFRTQDLDHPSSSSAWMEPRYKEAATHCALLQEHAQRCFVRGLFRSLQQAQSVTCQDLLTAVDACEELLQEVDITSFLLALCGHTWGLPHAPPSPGPLSPGPFSSSIEEGPEPRERAILVSESSIETEDLSEPEFQSTRVPGNSDPGPEISLTDVCQLRGEAHDALHSLIQEKFLEISRLHFRTVPSNPHYFFYCPPSSRREDEGPRDTVDRKVSDLEFSEAELVGEEGDTSACCVVTESDPELEVEYRESREPDLGPAGLDSASLSDADTVNPDEDSFSILGGDSPTGPDSLMHDLPPLFLHLTCSVRLRGQHSSVPVCSLPTCLGQVLSSLEGPPVGGRVPLRDLSITLDVFVLTLPLEVELPPASDPQHHRSTSESSASFPRSPGQPSSLRSDDGLGPPLPPPEEERHPGLSSLATPHRLAIESTMSEIRWLLEDEMVGALRRGGIPQSPALHRAAAHIHSSSGRSTCLRQAPPLSFVFGPERSLTQFKEEFRRLHLPGHVLLEDPDSGFFFVAVGQQPGGLHGEPPSSAWAWHNHEDRAEDAEGEVLTASPQVPGSLEDSECTPLISLPSLSQGGSQPGPSRGLSLMSSQGSVDSDHLGYDGGSSGSDSEGPGETLGEKALFTLRTPPGPAPPQPSLSVLPGPSLPDFWLIVRILQDRVEVYAHARSLNREDGGPGTECRHLQQLLVRCVGEICREVNQRLLLQDLHDSHVCNSLLVAESEEDLWRSEMPFHSRQRVVLPSDDYAADESCAPRGYLAATMQFVPGHFSCDVVWGTVIRVHSRLKMGPSMGVSRAIQALRSVLNAFSVVNRKNMFVYQERATKAVYYLRLLETSCSDRPWEGDTLTPSLALSRSQEPIYSEDSAAPRSPLDMASSRSSDAVRPVGQVDRHIQLLVHGVGQAGPEITDELVRVLRRRLDEATLDIITVMLVRNCKLTPADVEFIQPPGSLPSEVLHLVLPPSCRPWLPALAWYLRQNLLTFLHSPKYTDSNSRNHFQHPLPAQGGLPDLDIYLYNKPGGQGTGGKGVACITLAFVEEGGAPISLASWPPSSPGPPGPLQEEEFEQLTQVIRCPNTPDNSQAQDGSPQLRLDVWEKGNISIVQLEEKLRAAARQALADAIMELRLLPASLCTEDIPPGSLKSGPLETKSPACRASTFPSTPVSGEPVTPPSKAGRRSFWDMLSKTEAGDLGSPKTTDDIVLDRPEDTRGRRRHKTENVRTPGGSERAPGSDSGAQRQRRRTTQLEEGEVGTLHPVFAHVIQRWMGFMVQIGCASVSRSSTHMVSRFLLPSILSEFTTLVISMAGDTSVRVFEQHLGSEPGLFSPCFPGQLGPAPRPAAERHLLLLGRNFAQWRRPTQQAAKAVQRFEAGGDGSPGRGAPRQRLLLLEVTDKKLQLLTYNWAPDLGAALGRALIRLAQWQNARAHLISCLLSQKLGLFHHCGQLDFPVRDGKEPNPFLLPTMEVETLIRNASPPLSREQGRLSGSSRGGGSLSLDTFPFDEALRDITAARPSSTGGPAPRPPDPVTYHGQQFLEIKMTERKELERQMKMENLFVTWQQRSAPASMPISAGELETLKQSSRLVHYCATALLFDPAAWLHGPPETSAPSEGQRRLRPESGSGGRELPTSCESSDVPPPGAREEPWLKELSLAFLQQYVQYLQSIGFVLVPLRPPSPARSTSRLRAMAVLGTEGRGSFSCPKAKTEGSPKSTSTPVTTYHLQRALPGGIILMELTFQGCYFCVKQFALECSRIPMGQAVNSQLSLLFTEECDKVRDLMHVHSFSYDFHLRLVHQHVLGAHLVLRHGYHLTTFLQHFLAHHPDGPHFGRNHIYQGTLELPTPLIAAHQLYNYVADHASSYHMKPLRMARPGGLEHNEYALVSAWHSSGSYLDSEGLRHQDDFDVSLLVCHSAAPFEEQGEAERHVLRLQFFVVLTSQRELFPRLTADMRRFRKPSRLSLEPEAPGSLVGSPGEASGIMLAPGPAPLFPPLAAEVGMARARLAQLVRLAGGHCRRDTLWKRLFLLEPPGPDRLRLGGRLALAELEELLEAVHAKSIADIDPQLDCFLSMTVSWYQSLIKVLLSRFPQSCRHFQSPDLGTQYLVVLNQKFTDCFVLVFLDSHLGKTSLTVVFREPFPVQPQESESPPAQLVSTYHHLESVINTACFTLWTRLL", "length": 3431 }, "evidence": [ { "id": "A0A8V0ZJY5", "url": "https://omabrowser.org/oma/group/A0A8V0ZJY5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5T011-1", "protein_name": "KICSTOR complex protein SZT2", "gene_name": "SZT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASERPEPEVEEAGQVFLLMKKDYRISRNVRLAWFLSHLHQTVQATPQEMLLQSEQELEVLSVLPPGWQPDEPVVPRPFLLVPSTRVTFLAWQYRFVIELDLSPSTGIVDDSTGEILFDEVFHALSRCLGGLLRPFRVPGSCIDFQPEIYVTIQAYSSIIGLQSHQVLVQGCLLDPSQREVFLQQIYEQLCLFEDKVATMLQQQYDPQSQAEDQSPDSGDLLGRKVGVSMVTADLGLVSMIRQGILALQLLPSNSSAGIIVITDGVTSVPDVAVCETLLNQLRSGTVACSFVQVGGVYSYDCSFGHVPNVELMKFIAMATFGSYLSTCPEPEPGNLGLTVYHRAFLLYSFLRSGEALNPEYYCGSQHRLFNEHLVSASSNPALALRRKKHTEKEVPADLVSTVSVRLREGYSVREVTLAKGGSQLEVKLVLLWKHNMRIEYVAMAPWPLEPEGPRVTRVEVTMEGGYDILHDVSCALRQPIRSLYRTHVIRRFWNTLQSINQTDQMLAHLQSFSSVPEHFTLPDSTKSGVPLFYIPPGSTTPVLSLQPSGSDSSHAQFAAYWKPVLSMDANSWQRWLHMHRLVLILEHDTPIPKHLHTPGSNGRYSTIQCRISHSSLTSLLRDWSSFVLVEGYSYVKLLSSAPDQPPNSFYMVRIISKAPCMVLRLGFPIGTPAPARHKIVSGLREEILRLRFPHRVQSKEPTPKVKRKGLGGAGGGSSPSKSPPVLGPQQALSDRPCLVVLHKPLDKLLIRYEKLPLDYRAPFLLTLEPPGPLPLVSGRSASSSLASLSRYLYHQRWLWSVPSGLAPALPLSAIAQLLSILTEVRLSEGFHFACSGEGIINMVLELPIQNEPPGQAAAEEKHTCVVQYILFPPHSTSTKDSFSTDDDNDVEVEALEGDSELNLVTEVWVEPQYGRVGPGPGIWKHLQDLTYSEIPQALHPRDAACIGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHFDLMGLLPQCQQLQMFFLLLAREPEGVPFAEGSCPANDMVLCLLHSCLGQELSDREIPLTPVDQAAFLSEVLRRTCHVPGAEGPLLGVHGIPKEQAVGSTQATGDSAFTSLSVGLPETLKPLISAQPPQWRCYARLVNPQHVFLTFLPATFSDVQRLAACGLEGPPQEETKPKFGDWSGAPSLKDLGGTGIKATKSHVPVLSVTLASDNAQNQGELSPPFRRDLQAYAGRQASQTESADGPRTRCPVYIYSCSLEALREQMVGMQPPQAPRDLIFRTQFLDHPSPSSAWMEPRYKEAANHCALLQEHAQRCYVRGLFRSLQQAQSVTSQDLLTAVDACEELLQEIDITPFLLALCGHTWGLPHAPPSPGPLSPGPFSSSMEEGAEPRERAILASESSIETEDLSEPEFQSTRVPGIPDPGPEISLTDVCQLRGEAHGALHSVIQEKFLEISRLHFRTVPSNPHYFFYCPPSSRREDEGPRDTVDRKISDLEFSEAELMGEEGDTSACCVVTESDPELEVEYRESRESDLGPAGLDSASLSDVDTVNPDEDSFSILGGDSPTGPESFLHDLPPLFLHLTCSVRLRGQHSSVPVCSLPTCLGQVLSSLEGPPVGGRVPLRDLSVTLDVFMLTLPLEVELPTASDPQHHRSTSESSASFPRSPGQPSSLRSDDGLGPPLPPPEEERHPGLSNLATPHRLAIETTMNEIRWLLEDEMVGALRRGGIPQSPALHRAAAHIHSSPGRSTCLRQTLPLSFVFGPERSLTQFKEEFRRLHLPGHVLLEDPDSGFFFVAAGQQPGGSHGEPSSAAWAWHSHEDRAEGIEGETLTASPQAPGSPEDSEGVPLISLPRVPQGGSQPGPSRGLSLMSSQGSVDSDHLGYDGGSSGSDSEGPNDTLGEKAPFTLRTPPGPAPPQPSLSGLPGPCLPDFWLIVRVLQDRVEVYAHARSLIREDGGPGTECRHLQQLLVRRVGEICREVNQRLLLQDLHDSHVCNSLLVAESEEDLWRSETPFHSRQRAPLPSDDYAADESCAPRGYLAATMQFVPGHFSCDVVWGTVIRVHSRLKMGPSMGVSRAIQALRSVLNAFSVVNRKNMFVYQERATKAVYYLRLLETSCSDRPWKGDALPPSLALSRSQEPIYSEEASGPRSPLDMVSSRSSDAARPVGQVDRHIQLLVHGVGQAGPEITDELVRVLCRRLDEATLDVITVMLVRNCKLTPADVEFIQPPGSLPSEVLHLALPTSCRPWLPALAWYLRQNLLIFLHSPKYTDSNSRNHFQHPLPPQGGLPDLDIYLYNKPGGQGTGGKGVACITLAFVDEGGAPLSLALWPPSSPGPPDPLREEEFEQLTQVIRCPVVVDSSSAQNGAPRLRLDVWEKGNISIVQLEEKLRGAARQALADAIIELQLLPASLCTEDTPTGSLRNGSLETKSSAGRASTFPPAPVPGEPVTPPSKAGRRSFWDMLSKTECGDLGSPKTTDDIVLDRPEDTRGRRRHKTESVRTPGGAERAPGSDSGAQRQKRRTTQLEEGEVGTLHPVFARVAQRWMEFMVQIGCASVSRSSAHMVSRFLLPSILSEFTALVTSMAGDTSVRIFEQHLGSEPEIFGPCSPGQLGPSPRPAAERHLLLLGRNFLQWRRPTQQAAKAMQRFEPGGDGSSGRNAPRQRLLLLEVVDKKLQLLTYNWAPDLGAALGRALVRLVQWQNARAHLIFCLLSQKLGLFHHYGQLDFPVRDEKEPNPFLLPTMEVETLIRSASPPLSREQGRLSGSSRGGGPLPLDTFPFDEALRDITAARPSSVLGPVPRPPDPVTYHGQQFLEIKMAERRELERQMKMENLFVTWQQRSTPATMPISAGELETLKQSSRLVHYCATAMLFDPAAWLHGPPETSGPPDGQRRHRPESGSGSREAPTSCESLDVSPPGAREEPWLKELSLAFLQQYVQYLQSIGFVLVPLRPPSPARSTSRPRAMAILGTEGRGSFSCPKTKTDGSPKSTSSPVTTYHLQRALPGGIILMELAFQGCYFCVKQFALECSRIPMGQAVNSQLSMLFTEECDKVRDLMHVHSFSYDFHLRLVHQHVLGAHLVLRHGYHLTTFLRHFLAHHPDGPHFGRNHIYQGTLELPTPLIAAHQLYNYVADHASSYHMKPLRMARPGGPEHNEYALVSAWHSSGSYLDSEGLRHQDDFDVSLLVCHCAAPFEEQGEAERHVLRLQFFVVLTSQRELFPRLTADMRRFRKPPRLPPEPEAPGSSAGSPGEASGLILAPGPAPLFPPLAAEVGMARARLAQLVRLAGGHCRRDTLWKRLFLLEPPGPDRLRLGGRLALAELEELLEAVHAKSIGDIDPQLDCFLSMTVSWYQSLIKVLLSRFPQSCRHFQSPDLGTQYLVVLNQKFTDCFVLVFLDSHLGKTSLTVVFREPFPVQPQDSESPPAQLVSTYHHLESVINTACFTLWTRLL", "length": 3432 }, "evidence": [ { "id": "A0A8V0ZJY5", "url": "https://omabrowser.org/oma/group/A0A8V0ZJY5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5" } ], "pmid": "" }, { "name": "KICSTOR complex", "id": "GO:0140007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5" } ], "pmid": "" }, { "name": "GATOR1 complex", "id": "GO:1990130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5" } ], "pmid": "" }, { "name": "GATOR2 complex", "id": "GO:0061700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5" } ], "pmid": "" }, { "name": "protein localization to lysosome", "id": "GO:0061462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJY5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1150, "end_pos": 1152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2522, "end_pos": 2524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2873, "end_pos": 2875, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2883, "end_pos": 2885, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2934, "end_pos": 2936, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3092, "end_pos": 3094, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3370, "end_pos": 3372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 821, "end_pos": 823, "annotation": "n_glycosylation_sequon" }, { "start_pos": 934, "end_pos": 936, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 489, 689, 1995 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1150, "end_pos": 1152 }, { "start_pos": 2522, "end_pos": 2524 }, { "start_pos": 2873, "end_pos": 2875 }, { "start_pos": 2883, "end_pos": 2885 }, { "start_pos": 2934, "end_pos": 2936 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 3092, "end_pos": 3094 }, { "start_pos": 3370, "end_pos": 3372 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 544, "end_pos": 546 }, { "start_pos": 821, "end_pos": 823 }, { "start_pos": 934, "end_pos": 936 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKD6-1", "uniprot_ac": "A0A8V0ZKD6", "uniprot_id": "A0A8V0ZKD6_CHICK", "mass": { "chemical_mass": 119301.0, "monoisotopic_mass": 119301.0 }, "refseq": {}, "gene_names": [ { "name": "PDZRN3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" } ] } ], "protein_names": [ { "name": "PDZ domain containing ring finger 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDZRN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6", "locus": { "chromosome": "12", "start_pos": 16792297, "end_pos": 16913229, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020350", "url": "https://www.ensembl.org/id/ENSGALG00010020350" } ] } } ], "crossref": [ { "id": "A0A8V0ZKD6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKD6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06715", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06715", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16718", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16718", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003613", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003613", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCX1", "url": "https://www.orthodb.org/?gene=A0A8V0ZCX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDY8", "url": "https://www.orthodb.org/?gene=A0A8V0ZDY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEC5", "url": "https://www.orthodb.org/?gene=A0A8V0ZEC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKD6", "url": "https://www.orthodb.org/?gene=A0A8V0ZKD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15545", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15545", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15545:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15545:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGFELDRFSGEVDPDFKCNLCNKVLEDPLTTPCGHVFCAGCVLPWVVQQGSCPANCQRISAKELNHVLPLKSLILKLDIKCDNHARGCEAVVPLQHLGEHAETCDFSPAKCRNRGCRQVLNLRDVEAHMRERCEARPAGLCEQGCGLMLTHGERRSGGHSCLRALRAHGAALQARAAALEKALKKEALRAGKREQSLLSRLAAAQLELQVTALRYQKRFTQYSARLDALARARSASPGKGEETKALTLVLHRDSGSLGFNIIGGRPCVDNQDGSASEGIFVSKIVDTGPAAKEGGLQIHDRIIEVNGKDLSKATHEQAVEAFKTAKEPIVVQVLRRTPRTKIFTAPESQLVDVGTQTDITFEHIMALSKMGSPTPPVSVLDPYLLPEDHPSVHEYYDPNDYMGGIHQEMDRDELELEEVDLHRVNSQDKLGLTVCYRTDDEDDTGIYVSEIDPNSIAAKDGRLREGDRIIQINGIEVQNREEAVALLTSEESKNVSLLVARPEIQLDEGWMDDDRNDFLDDLHMDMLEEQHHQAMQFTASMLQQKHEEDGGTTDTATILSNQHEKDSGVGRTDDSTRNDESSEQENNADDHTTSSNTLGSQKKLTYSHDTLGSGDMQFSNESFISADCTDVDFLGIPVDECERFRELLELKCQVKSANPYSLYYHTSTLDMSKSDQESVDKELEMLNEELRNIELECLNIVRAHKMQQLKDQYREPWMLHNSGFRNYNTSIDVRRHELSDITELPEKSDKDSSSAYNTGESCRSTPLTLEISPDNSLRRTAEGINCQGNEGAVAYNVSQKNLFASSESHESSTGKCHSSAKDPDTSKQMECKERKASDGSKSPTHGQKPSGSYVSPYHHSPYKHAHIPAHAQHYQSYMQLIQQKSAVEYAQSQMSLVSMCKDFNASQSEPRMEWKVKVRSDGTRYITKRPVRDRLLRERAIKIKEERSGMTTDDDAISEMKMGRYWSKEERKQHLVKAKEQRRRREFMMQSRLDCLKEQQGAEEKKEMNIIELSHKKMMKKRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV", "length": 1059, "header": "tr|A0A8V0ZKD6-1|A0A8V0ZKD6_CHICK Isoform 1 of PDZ domain containing ring finger 3 OS=Gallus gallus OX=9031 GN=PDZRN3 PE=4 SV=1 CANONICAL=A0A8V0ZKD6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6/entry#A0A8V0ZCX1-1", "sequence": { "sequence": "MGCSLCTLQKQEEQYKLLYEVCQVNGKDLSKATHEQAVEAFKTAKEPIVVQVLRRTPRTKIFTAPESQLVDVGTQTDITFEHIMALSKMGSPTPPVSVLDPYLLPEEQRKTTKEVGKDDFIHPSVHEYYDPNDYMGGIHQEMDRDELELEEVDLHRVNSQDKLGLTVCYRTDDEDDTGIYVSEIDPNSIAAKDGRLREGDRIIQINGIEVQNREEAVALLTSEESKNVSLLVARPEIQLDEGWMDDDRNDFLDDLHMDMLEEQHHQAMQFTASMLQQKKHEEDGGTTDTATILSNQHEKDSGVGRTDDSTRNDESSEQENNADDHTTSSNTLGSQKKLTYSHDTLGSGDMQFSNESFISADCTDVDFLGIPVDECERFRELLELKCQVKSANPYSLYYHTSTLDMSKSDQESVDKELEMLNEELRNIELECLNIVRAHKMQQLKDQYREPWMLHNSGFRNYNTSIDVRRHELSDITELPEKSDKDSSSAYNTGESCRSTPLTLEISPDNSLRRTAEGINCQGNEGAVAYNVSQKNLFASSESHESSTGKCHSSAKDPDTSKQMECKERKASDGSKSPTHGQKPSGSYVSPYHHSPYKHAHIPAHAQHYQSYMQLIQQKSAVEYAQSQMSLVSMCKDFNASQSEPRMEWKVKVRSDGTRYITKRPVRDRLLRERAIKIKEERSGMTTDDDAISEMKMGRYWSKEERKQHLVKAKEQRRRREFMMQSRLDCLKEQQGAEEKKEMNIIELSHKKMMKKRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV", "length": 793, "header": "tr|A0A8V0ZCX1-1|A0A8V0ZKD6_CHICK Computationally mapped isoform of PDZ domain containing ring finger 3 OS=Gallus gallus OX=9031 GN=PDZRN3 PE=4 SV=1 CANONICAL=A0A8V0ZKD6-1" }, "locus": { "chromosome": "12", "start_pos": 16820353, "end_pos": 16793301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049155.1", "url": "https://www.ensembl.org/id/ENSGALT00010049155.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029062.1", "url": "https://www.ensembl.org/id/ENSGALP00010029062.1" } ] } }, { "isoform_ac": "A0A8V0ZDY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6/entry#A0A8V0ZDY8-1", "sequence": { "sequence": "MGQQPFGWVNGKDLSKATHEQAVEAFKTAKEPIVVQVLRRTPRTKIFTAPESQLVDVGTQTDITFEHIMALSKMGSPTPPVSVLDPYLLPEDHPSVHEYYDPNDYMGGIHQEMDRDELELEEVDLHRVNSQDKLGLTVCYRTDDEDDTGIYVSEIDPNSIAAKDGRLREGDRIIQINGIEVQNREEAVALLTSEESKNVSLLVARPEIQLDEGWMDDDRNDFLDDLHMDMLEEQHHQAMQFTASMLQQKKHEEDGGTTDTATILSNQHEKDSGVGRTDDSTRNDESSEQENNADDHTTSSNTLGSQKKLTYSHDTLGSGDMQFSNESFISADCTDVDFLGIPVDECERFRELLELKCQVKSANPYSLYYHTSTLDMSKSDQESVDKELEMLNEELRNIELECLNIVRAHKMQQLKDQYREPWMLHNSGFRNYNTSIDVRRHELSDITELPEKSDKDSSSAYNTGESCRSTPLTLEISPDNSLRRTAEGINCQGNEGAVAYNVSQKNLFASSESHESSTGKCHSSAKDPDTSKQMECKERKASDGSKSPTHGQKPSGSYVSPYHHSPYKHAHIPAHAQHYQSYMQLIQQKSAVEYAQSQMSLVSMCKDFNASQSEPRMEWKVKVRSDGTRYITKRPVRDRLLRERAIKIKEERSGMTTDDDAISEMKMGRYWSKEERKQHLVKAKEQRRRREFMMQSRLDCLKEQQGAEEKKEMNIIELSHKKMMKKRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV", "length": 764, "header": "tr|A0A8V0ZDY8-1|A0A8V0ZKD6_CHICK Computationally mapped isoform of PDZ domain containing ring finger 3 OS=Gallus gallus OX=9031 GN=PDZRN3 PE=4 SV=1 CANONICAL=A0A8V0ZKD6-1" }, "locus": { "chromosome": "12", "start_pos": 16842008, "end_pos": 16793301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049158.1", "url": "https://www.ensembl.org/id/ENSGALT00010049158.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029064.1", "url": "https://www.ensembl.org/id/ENSGALP00010029064.1" } ] } }, { "isoform_ac": "A0A8V0ZEC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6/entry#A0A8V0ZEC5-1", "sequence": { "sequence": "MGFELDRFSGEVDPDFKCNLCNKVLEDPLTTPCGHVFCAGCVLPWVVQQGSCPANCQRISAKELNHVLPLKSLILKLDIKCDNHARGCEAVVPLQHLGEHAETCDFSPAKCRNRGCRQVLNLRDVEAHMRERCEARPAGLCEQGCGLMLTHGERRSGGHSCLRALRAHGAALQARAAALEKALKKEALRAGKREQSLLSRLAAAQLELQVTALRYQKRFTQYSARLDALARARSASPGKGEETKALTLVLHRDSGSLGFNIIGGRPCVDNQDGSASEGIFVSKIVDTGPAAKEGGLQIHDRIIEVNGKDLSKATHEQAVEAFKTAKEPIVVQVLRRTPRTKIFTAPESQLVDVGTQTDITFEHIMALSKMGSPTPPVSVLDPYLLPEDHPSVHEYYDPNDYMGGIHQEMDRDELELEEVDLHRVNSQDKLGLTVCYRTDDEDDTGIYVSEIDPNSIAAKDGRLREGDRIIQINGIEVQNREEAVALLTSEESKNVSLLVARPEIQKKHEEDGGTTDTATILSNQHEKDSGVGRTDDSTRNDESSEQENNADDHTTSSNTLGSQKKLTYSHDTLGSGDMQFSNESFISADCTDVDFLGIPVDECERFRELLELKCQVKSANPYSLYYHTSTLDMSKSDQESVDKELEMLNEELRNIELECLNIVRAHKMQQLKDQYREPWMLHNSGFRNYNTSIDVRRHELSDITELPEKSDKDSSSAYNTGESCRSTPLTLEISPDNSLRRTAEGINCQGNEGAVAYNVSQKNLFASSESHESSTGKCHSSAKDPDTSKQMECKERKASDGSKSPTHGQKPSGSYVSPYHHSPYKHAHIPAHAQHYQSYMQLIQQKSAVEYAQSQMSLVSMCKDFNASQSEPRMEWKVKVRSDGTRYITKRPVRDRLLRERAIKIKEERSGMTTDDDAISEMKMGRYWSKEERKQHLVKAKEQRRRREFMMQSRLDCLKEQQGAEEKKEMNIIELSHKKMMKKRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV", "length": 1021, "header": "tr|A0A8V0ZEC5-1|A0A8V0ZKD6_CHICK Computationally mapped isoform of PDZ domain containing ring finger 3 OS=Gallus gallus OX=9031 GN=PDZRN3 PE=4 SV=1 CANONICAL=A0A8V0ZKD6-1" }, "locus": { "chromosome": "12", "start_pos": 16912978, "end_pos": 16793301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049165.1", "url": "https://www.ensembl.org/id/ENSGALT00010049165.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029068.1", "url": "https://www.ensembl.org/id/ENSGALP00010029068.1" } ] } }, { "isoform_ac": "A0A8V0ZKD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6/entry#A0A8V0ZKD6-1", "sequence": { "sequence": "MGFELDRFSGEVDPDFKCNLCNKVLEDPLTTPCGHVFCAGCVLPWVVQQGSCPANCQRISAKELNHVLPLKSLILKLDIKCDNHARGCEAVVPLQHLGEHAETCDFSPAKCRNRGCRQVLNLRDVEAHMRERCEARPAGLCEQGCGLMLTHGERRSGGHSCLRALRAHGAALQARAAALEKALKKEALRAGKREQSLLSRLAAAQLELQVTALRYQKRFTQYSARLDALARARSASPGKGEETKALTLVLHRDSGSLGFNIIGGRPCVDNQDGSASEGIFVSKIVDTGPAAKEGGLQIHDRIIEVNGKDLSKATHEQAVEAFKTAKEPIVVQVLRRTPRTKIFTAPESQLVDVGTQTDITFEHIMALSKMGSPTPPVSVLDPYLLPEDHPSVHEYYDPNDYMGGIHQEMDRDELELEEVDLHRVNSQDKLGLTVCYRTDDEDDTGIYVSEIDPNSIAAKDGRLREGDRIIQINGIEVQNREEAVALLTSEESKNVSLLVARPEIQLDEGWMDDDRNDFLDDLHMDMLEEQHHQAMQFTASMLQQKHEEDGGTTDTATILSNQHEKDSGVGRTDDSTRNDESSEQENNADDHTTSSNTLGSQKKLTYSHDTLGSGDMQFSNESFISADCTDVDFLGIPVDECERFRELLELKCQVKSANPYSLYYHTSTLDMSKSDQESVDKELEMLNEELRNIELECLNIVRAHKMQQLKDQYREPWMLHNSGFRNYNTSIDVRRHELSDITELPEKSDKDSSSAYNTGESCRSTPLTLEISPDNSLRRTAEGINCQGNEGAVAYNVSQKNLFASSESHESSTGKCHSSAKDPDTSKQMECKERKASDGSKSPTHGQKPSGSYVSPYHHSPYKHAHIPAHAQHYQSYMQLIQQKSAVEYAQSQMSLVSMCKDFNASQSEPRMEWKVKVRSDGTRYITKRPVRDRLLRERAIKIKEERSGMTTDDDAISEMKMGRYWSKEERKQHLVKAKEQRRRREFMMQSRLDCLKEQQGAEEKKEMNIIELSHKKMMKKRNKKIFDNWMTIQELLTHGTKSPDGTRVYNSFLSVTTV", "length": 1059, "header": "tr|A0A8V0ZKD6-1|A0A8V0ZKD6_CHICK Isoform 1 of PDZ domain containing ring finger 3 OS=Gallus gallus OX=9031 GN=PDZRN3 PE=4 SV=1 CANONICAL=A0A8V0ZKD6-1" }, "locus": { "chromosome": "12", "start_pos": 16912978, "end_pos": 16793301, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049162.1", "url": "https://www.ensembl.org/id/ENSGALT00010049162.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029066.1", "url": "https://www.ensembl.org/id/ENSGALP00010029066.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" } ], "pmid": "" }, { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 796, "end_pos": 798, "annotation": "n_glycosylation_sequon" }, { "start_pos": 904, "end_pos": 906, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 247, "end_pos": 337, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZKD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 53, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZKD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKD6" }, { "id": "PS51081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SIAH-type", "eco_id": "ECO_0000259", "start_pos": 76, "end_pos": 134, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 494, "end_pos": 496 }, { "start_pos": 620, "end_pos": 622 }, { "start_pos": 728, "end_pos": 730 }, { "start_pos": 796, "end_pos": 798 }, { "start_pos": 904, "end_pos": 906 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZK32-1", "uniprot_ac": "A0A8V0ZK32", "uniprot_id": "A0A8V0ZK32_CHICK", "mass": { "chemical_mass": 55910.0, "monoisotopic_mass": 55910.0 }, "refseq": {}, "gene_names": [ { "name": "ODR4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32" } ] } ], "protein_names": [ { "name": "Protein odr-4 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in the trafficking of a subset of G-protein coupled receptors.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ2#function" }, { "database": "UniProtKB", "id": "ARBA00003891", "url": "https://www.uniprot.org/uniprotkb/ARBA00003891#function" }, { "database": "UniProtKB", "id": "A0A8V0ZCZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCZ8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZK32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ODR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32", "locus": { "chromosome": "8", "start_pos": 10240924, "end_pos": 10262322, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021504", "url": "https://www.ensembl.org/id/ENSGALG00010021504" } ] } } ], "crossref": [ { "id": "A0A8V0ZK32", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZK32", "database": "AlphaFoldDB", "categories": [] }, { "id": "424455", "url": "https://www.ncbi.nlm.nih.gov/gene/424455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCZ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZCZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIJ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZIJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK32", "url": "https://www.orthodb.org/?gene=A0A8V0ZK32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33966:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33966:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZCZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTKASSSRRGLNAGGASRCELGCSVMQQEVVAQAETVIPGLEPAAMGRTYFVEEAVGRYLSDLSVKFKPYVTGLLIGQCSPQRDYIIRAARTPPKEEQKEGNTSPSKLDSIDEEWFTAHASQISRMLPGGLLVLGVFIIATPELSKDCQNTLRKLIFSIEKSLTKRRLWKPADEDVSDRAALQICSATKKCFIGYFCPQGSAKPADWKYQSALSASWLSLGCTVNVNIHIPLLATSPNHDLEKNTKNGLNRWSKQIEDSIFLINGQVKDNDIELLEGQKKLRGNTHSGTQIFDVKVLTQLSQGSSHRSTATVQVCSGSINLKGAVKCRAYVHNNKPKVKEAVLALKRDIINTLSDRCEILFEDLILNEGRCKKNFERVYHVLPQRLFVPFAGSNVMLSDYKFGDEAAGEIQERFVEMLDQFVQAEDIHIAEEVNTVGICSLSEKMDDTQLEQLTKATLLLKLQQNMEIMMGPFSIKFASTALLLFSQLVRLIKKQTNKQNPS", "length": 503, "header": "tr|A0A8V0ZK32-1|A0A8V0ZK32_CHICK Isoform 1 of Protein odr-4 homolog OS=Gallus gallus OX=9031 GN=ODR4 PE=3 SV=1 CANONICAL=A0A8V0ZK32-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32/entry#A0A8V0ZCZ8-1", "sequence": { "sequence": "MGTKASSSRRGLNAGGASRCELGCSVMQQEVVAQAETVIPGLEPAAMGRTYFVEEAVGRYLSDLSVKFKPYVTGLLIGQCSPQRDYIIRAARTPPKEEQKEGNTSPSKLDSIDEEWFTAHASQISRMLPGGLLVLGVFIIATPELSKDCQNTLRKLIFSIEKSLTKRRLWKPADEDVSDRAALQICSATKKIVCRTYDVQDPKGSAKPADWKYQSALSASWLSLGCTVNVNIHIPLLATSPNHDLEKNTKNGLNRWSKQIEDSIFLINGQVKDNDIELLEGQKKLRGNTHSGTQIFDVKVLTQLSQGSSHRSTATVQVCSGSINLKGAVKCRAYVHNNKPKVKEAVLALKRDIINTLSDRCEILFEDLILNEGRCKKNFERVYHVLPQRLFVPFAGSNVMLSDYKFGDEAAGEIQERFVEMLDQFVQAEDIHIAEEVNTVGICSLSEKMDDTQLEQLTKATLLLKLQQNMGVVIAVAVAVFASIFSFNYFSD", "length": 492, "header": "tr|A0A8V0ZCZ8-1|A0A8V0ZK32_CHICK Computationally mapped isoform of Protein odr-4 homolog OS=Gallus gallus OX=9031 GN=ODR4 PE=3 SV=1 CANONICAL=A0A8V0ZK32-1" }, "locus": { "chromosome": "8", "start_pos": 10261830, "end_pos": 10242036, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052154.1", "url": "https://www.ensembl.org/id/ENSGALT00010052154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031149.1", "url": "https://www.ensembl.org/id/ENSGALP00010031149.1" } ] } }, { "isoform_ac": "A0A8V0ZIJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32/entry#A0A8V0ZIJ2-1", "sequence": { "sequence": "MGRTYFVEEAVGRYLSDLSVKFKPYVTGLLIGQCSPQRDYIIRAARTPPKEEQKEGNTSPSKLDSIDEEWFTAHASQISRMLPGGLLVLGVFIIATPELSKDCQNTLRKLIFSIEKSLTKRRLWKPADEDVSDRAALQICSATKKIVCRTYDVQDPKGSAKPADWKYQSALSASWLSLGCTVNVNIHIPLLATSPNHDLEKNTKNGLNRWSKQIEDSIFLINGQVKDNDIELLEGQKKLRGNTHSGTQIFDVKVLTQLALKRDIINTLSDRCEILFEDLILNEGRCKKNFERVYHVLPQRLFVPFAGSNVMLSDYKFGDEAAGEIQERFVEMLDQFVQAEDIHIAEEVNTVGICSLSEKMDDTQLEQLTKATLLLKLQQNMGVVIAVAVAVFASIFSFNYFSD", "length": 403, "header": "tr|A0A8V0ZIJ2-1|A0A8V0ZK32_CHICK Computationally mapped isoform of Protein odr-4 homolog OS=Gallus gallus OX=9031 GN=ODR4 PE=3 SV=1 CANONICAL=A0A8V0ZK32-1" }, "locus": { "chromosome": "8", "start_pos": 10261412, "end_pos": 10242036, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052157.1", "url": "https://www.ensembl.org/id/ENSGALT00010052157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031151.1", "url": "https://www.ensembl.org/id/ENSGALP00010031151.1" } ] } }, { "isoform_ac": "A0A8V0ZK32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32/entry#A0A8V0ZK32-1", "sequence": { "sequence": "MGTKASSSRRGLNAGGASRCELGCSVMQQEVVAQAETVIPGLEPAAMGRTYFVEEAVGRYLSDLSVKFKPYVTGLLIGQCSPQRDYIIRAARTPPKEEQKEGNTSPSKLDSIDEEWFTAHASQISRMLPGGLLVLGVFIIATPELSKDCQNTLRKLIFSIEKSLTKRRLWKPADEDVSDRAALQICSATKKCFIGYFCPQGSAKPADWKYQSALSASWLSLGCTVNVNIHIPLLATSPNHDLEKNTKNGLNRWSKQIEDSIFLINGQVKDNDIELLEGQKKLRGNTHSGTQIFDVKVLTQLSQGSSHRSTATVQVCSGSINLKGAVKCRAYVHNNKPKVKEAVLALKRDIINTLSDRCEILFEDLILNEGRCKKNFERVYHVLPQRLFVPFAGSNVMLSDYKFGDEAAGEIQERFVEMLDQFVQAEDIHIAEEVNTVGICSLSEKMDDTQLEQLTKATLLLKLQQNMEIMMGPFSIKFASTALLLFSQLVRLIKKQTNKQNPS", "length": 503, "header": "tr|A0A8V0ZK32-1|A0A8V0ZK32_CHICK Isoform 1 of Protein odr-4 homolog OS=Gallus gallus OX=9031 GN=ODR4 PE=3 SV=1 CANONICAL=A0A8V0ZK32-1" }, "locus": { "chromosome": "8", "start_pos": 10261830, "end_pos": 10243228, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052146.1", "url": "https://www.ensembl.org/id/ENSGALT00010052146.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031142.1", "url": "https://www.ensembl.org/id/ENSGALP00010031142.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJ39-1", "uniprot_ac": "A0A8V0ZJ39", "uniprot_id": "A0A8V0ZJ39_CHICK", "mass": { "chemical_mass": 62649.0, "monoisotopic_mass": 62649.0 }, "refseq": { "ac": "XP_015148734", "name": "leiomodin-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148734" }, "gene_names": [ { "name": "LMOD3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ] }, { "name": "LMOD3", "type": "synonym", "evidence": [ { "id": "XP_015148734", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148734" } ] } ], "protein_names": [ { "name": "Leiomodin-3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39/entry#names_and_taxonomy" } ] }, { "name": "leiomodin-3", "type": "synonym", "evidence": [ { "id": "XP_015148734", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148734" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148734.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148734", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148734" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LMOD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39", "locus": { "chromosome": "12", "start_pos": 15517254, "end_pos": 15528026, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020088", "url": "https://www.ensembl.org/id/ENSGALG00010020088" } ] } } ], "crossref": [ { "id": "A0A8V0ZJ39", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJ39", "database": "AlphaFoldDB", "categories": [] }, { "id": "426075", "url": "https://www.ncbi.nlm.nih.gov/gene/426075", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426075", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426075", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GMWERLG", "url": "https://omabrowser.org/oma/group/GMWERLG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD23", "url": "https://www.orthodb.org/?gene=A0A8V0ZD23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ39", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10901", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10901", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10901:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10901:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148734", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148734", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSELSQTSDEDVSPEDINEDEILANLSPEELKELQSEMEVMAPDPELPTGMIQRDQTEKPPTGSFDHRSLVDYLYWQKASRRMLEDERVPVTLLPSERMTAEEMGDGGGPGDAGGRRGPDADGKERHYKNESVSHAVTQPGEMNRDGSNEEGEDEEEEEEEGEEEEDESESETKETCVNENHHSDQTSKQSGMESGETTEKPEENEKKISKLNIPKKLALDTSFMKLSARPSGNQTNLEESLEKVRKNNPDMKELNLNNIENIPKEMLIDFVNAMKKNKNIKTFSLANVGADDNVAFALANMLRENRSITTLNIDSNFISGKGVVAIMRCLQYNEMLTEFRFHNQRSMLGHQAEMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLSRNLDKQRQKRQEGQRQQQMKEQRELITMLENGLGLPPGMWEMLGGPLPQPRPQEAPPAPKPPIPTSAPQGRGKESMRPADPEQPRGAEPSFRVIKLKKIQRKAAVPKYVEPTEKTNLKDVIKTLKPIPRRRPPPLVEITPRDQLLNDIRQSNVAYLKPVPLPKQLE", "length": 554, "header": "tr|A0A8V0ZJ39-1|A0A8V0ZJ39_CHICK Isoform 1 of Leiomodin-3 OS=Gallus gallus OX=9031 GN=LMOD3 PE=3 SV=1 CANONICAL=A0A8V0ZJ39-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39/entry#A0A8V0ZD23-1", "sequence": { "sequence": "MSELSQTSDEDVSPEDINEDEILANLSPEELKELQSEMEVMAPDPELPTGMIQRDQTEKPPTGSFDHRSLVDYLYWQKASRRMLEDERVPVTLLPSERMTAEEMGDGGGPGDAGGRRGPDADGKERHYKNESVSHAVTQPGEMNRDGSNEEGEDEEEEEEEGEEEEDESESETKETCVNENHHSDQTSKQSGMESGETTEKPEENEKKISKLNIPKKLALDTSFMKLSARPSGNQTNLEESLEKVRKNNPDMKELNLNNIENIPKEMLIDFVNAMKKNKNIKTFSLANVGADDNVAFALANMLRENRSITTLNIDSNFISGKGVVAIMRCLQYNEMLTEFRFHNQRSMLGHQAEMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLSRNLDKQRQKRQEGQRQQQMKEQRELITMLENGLGLPPGMWEMLGGPLPQPRPQEAPPAPKPPIPTSAPQGRGKESMRPADPEQPRGAEPSFRVIKLKKIQRKAAVPKYVEPTEKTNLKDVIKTLKPIPRRRPPPLVEITPRDQLLNDIRQSNVAYLKPVSV", "length": 549, "header": "tr|A0A8V0ZD23-1|A0A8V0ZJ39_CHICK Computationally mapped isoform of Leiomodin-3 OS=Gallus gallus OX=9031 GN=LMOD3 PE=3 SV=1 CANONICAL=A0A8V0ZJ39-1" }, "locus": { "chromosome": "12", "start_pos": 15522851, "end_pos": 15519818, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048519.1", "url": "https://www.ensembl.org/id/ENSGALT00010048519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028610.1", "url": "https://www.ensembl.org/id/ENSGALP00010028610.1" } ] } }, { "isoform_ac": "A0A8V0ZJ39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39/entry#A0A8V0ZJ39-1", "sequence": { "sequence": "MSELSQTSDEDVSPEDINEDEILANLSPEELKELQSEMEVMAPDPELPTGMIQRDQTEKPPTGSFDHRSLVDYLYWQKASRRMLEDERVPVTLLPSERMTAEEMGDGGGPGDAGGRRGPDADGKERHYKNESVSHAVTQPGEMNRDGSNEEGEDEEEEEEEGEEEEDESESETKETCVNENHHSDQTSKQSGMESGETTEKPEENEKKISKLNIPKKLALDTSFMKLSARPSGNQTNLEESLEKVRKNNPDMKELNLNNIENIPKEMLIDFVNAMKKNKNIKTFSLANVGADDNVAFALANMLRENRSITTLNIDSNFISGKGVVAIMRCLQYNEMLTEFRFHNQRSMLGHQAEMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLSRNLDKQRQKRQEGQRQQQMKEQRELITMLENGLGLPPGMWEMLGGPLPQPRPQEAPPAPKPPIPTSAPQGRGKESMRPADPEQPRGAEPSFRVIKLKKIQRKAAVPKYVEPTEKTNLKDVIKTLKPIPRRRPPPLVEITPRDQLLNDIRQSNVAYLKPVPLPKQLE", "length": 554, "header": "tr|A0A8V0ZJ39-1|A0A8V0ZJ39_CHICK Isoform 1 of Leiomodin-3 OS=Gallus gallus OX=9031 GN=LMOD3 PE=3 SV=1 CANONICAL=A0A8V0ZJ39-1" }, "locus": { "chromosome": "12", "start_pos": 15522851, "end_pos": 15517743, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048522.1", "url": "https://www.ensembl.org/id/ENSGALT00010048522.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028613.1", "url": "https://www.ensembl.org/id/ENSGALP00010028613.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426075", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426075", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AV50-1", "protein_name": "Leiomodin-3", "gene_name": "FRMD4B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEHSRNSDQEEPFDREIDEDEILANLSPEELKELQSEMDVMAPDPRLPVGMIQKDQTDKPPTGNFDHKSLVDYMYWQKASRRMLEDERVPVTFVPSEEKPQEQRKEIDKGNKNMSQYLKEKLNNEIAAHKRESKSSDNEQETNDDDEDNEDDEDDEEDDAEDEEDEGDESDEKTKGEEEGEVKEPIRNGESNCQQVPNKAFEEQKDRPEAQEKFEKKISKLDPKKLALDTSFLKVSARPSGNQTDLDGSLRRVRQNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADESVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEISRLLKANTTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQQQLKEQKKLIAMLENGLGLPPGMWEMLGGPMPDSQMQEFLQPPPPKSLHPQTAPFSRRNEVMAKPAQPPKYRTDPDSFRVVKLKRIQRKSRMPEAREPPEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSNIAYLKPVQLPKELA", "length": 566 }, "evidence": [ { "id": "A0A8V0ZJ39", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ39/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7JQU1-1", "protein_name": "Leiomodin-3", "gene_name": "Lmod3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSEHSRNSDQEDTLSEELNEDEILANLSPEELKELQSEMEVMAPDPHLPVGMIQKDQTNKAPTGNFDHKSLVDYMYLQKASRRMVEDERVPVSFVQSEENTQKQHEVRDKGVKNMPQFLKEKLNSEILANKRESNGSKNTQETEDDEEDEDDEDEEDDEDEDDEDEEDDEDEDEKAKREKKEQIQNSSGACQKPTTKALEEQKDRPETKDKTEKKIAKLDPKKLALDTSFLKVSARPSGNQTDLDGSLRRVRQNDPDMKELNLNNIENIPREMLLDFVNAMKKNKHIKSFSLANVGADESVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEISRLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKRRQKRQEEQQQQQLKEQRKLIAMLENGLGLPPGMWERLGGPMPDPRMQEFFQPSSGHPLTAQEVPFGGRKEMIKNPPQPPQYKTDPDSFRVVKLKRIQRKSRMPEAREAQEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSNVAYLKPVQLPKELA", "length": 563 }, "evidence": [ { "id": "A0A8V0ZJ39", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ39/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A871-1", "protein_name": "Leiomodin-3", "gene_name": "Lmod3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEHSGNSDQEDTLSEELDEDEILANLSPEELKELQSEMEVMAPDPHLPVGMIQKDQTDKAPTGNFDHKSLVDYMYLQKASRRMLEDERVPVSFVQSEENTQKQHEVREKGIASMPQFLKEKLNSEILAKKRQSNGSNNVQETEDDEDEEDEEDEEDDEDEDEGEEGDEDEEDGDGEQANRGKNEAKEQVHNNASICQQPATRAMEEQKATRAMEEQKDTAETKGKGAKKIAKLDPKKLALDTSFLKVSARPSGNQTDLDGSLRRVRQNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKSFSLANVGADESVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEISRLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKRRQKRQEEQQQQQLKEQRKLIAMLENGLGLPPGMWERLGGPMPDPRMQEFFQPSPGRSLAAQEVPFGARKEMIKNPPQPPQYKTDPDSFRVVKLKRIQRKSRMPEARESQEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSNVAYLKPVQLPKELA", "length": 578 }, "evidence": [ { "id": "A0A8V0ZJ39", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ39/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F7X0-1", "protein_name": "Leiomodin-3", "gene_name": "lmod3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSERTEQESYTDKIDEDEILAGLSAEELKQLQSEMDDIAPDERVPVGLRQKDASHEMTVRDCTEPESEEEIDEDEILAGLSAEELKQLQSEMEEIAPDERVPVGMRQRDQTDKPPTGSFDHRSLVEYLYWEKESKRMLEEERVPTTLLPSQKTNEEHEAKNEDKVEELELVYEEIVEEVEGGQGDAVVDEVIEEVIMEVEEEDKVCDKPVKTDLDATDPTVTSEDGLQRPSESADANVEAKTDQSGLDTETKVNEEKKEDSTEPAPSSYENWVPEKEERVISKLKIPKLALGGNTFVKKTARPSGNETNLESTLDKIRNNNPSVTDVNLNNIENIPKEMLLDYVNSLKKNRHVKTFSIANTGADENVAFTLANMLKENRSITTLNIESNFITGKGIVAIIRCLQFNETLTELRFHNQRHMLGHHAEMEVSRLLKANNTLLKMGYHFELPGPRMVVTNLLTRNLDRQRQQRMEEQKLQQMKEQRKVMEMYEDSLNLPPGMLEMLGGYIPLSLLQNCQNGAEDIPEDSPEPSPQPSPPHQLCKTQHLAPQQHPPNLSTGNLFEEVQLKKTPKRRDPLLEWNQCDERKDGRPNVHLRSVPKKRSIAREGPVDERANLKDMIKTLKPVPRRREPPKVDLTPRDHLLSEIRQSNVAYLKAVPLPKILESQETSLF", "length": 670 }, "evidence": [ { "id": "A0A8V0ZJ39", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ39/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QA62-1", "protein_name": "Leiomodin-3", "gene_name": "Lmod3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGHSRNSEQEDTLSEELDEDELLANLSPEELKELQSEMEVMAPDPHLPVGMIQKDQTDKAPTGNFNHKSLVDYMYLQKASRRMLEDERVPVSFVQSEKNTQNQREVGDKGIKNMPQFLKEKLNSEILAKKRESNGSNNVQEAEDDDEDEEEEEEDDEDEEEEEEDEEDDEGEEDEDGEQANREKNDAKEQIHNNPGTYQQLATKTAHEQKDTSETKEKGEKKIAKLDPKKLALDTSFLKVSARPSGNQTDLDGSLRRVRQNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADESVAFALANMLRENRSVTTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEISRLLKANTTLLKMGYHFELPGPRMVVTNLLTRNQDKRRQKRQEEQQQQQLKEQRKLIAMLENGLGLPPGMWERLGGPMPDPRMQEFFQPASGRPLDAQEVPFGSRKEMIKNPPQPPQCKTDPDSFRVVKLKRIQRKSRMPEAREAQEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSNVAYLKPVQLPKELE", "length": 571 }, "evidence": [ { "id": "A0A8V0ZJ39", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ39/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q0VAK6-1", "protein_name": "Leiomodin-3", "gene_name": "LMOD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEHSRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQQQLKEQKKLIAMLENGLGLPPGMWELLGGPKPDSRMQEFFQPPPPRPPNPQNVPFSQRSEMMKKPSQAPKYRTDPDSFRVVKLKRIQRKSRMPEAREPPEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSSVAYLKPVQLPKELA", "length": 560 }, "evidence": [ { "id": "A0A8V0ZJ39", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ39/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "tropomyosin binding", "id": "GO:0005523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "striated muscle thin filament", "id": "GO:0005865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "myofibril", "id": "GO:0030016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030016", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "pointed-end actin filament capping", "id": "GO:0051694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "striated muscle cell development", "id": "GO:0055002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055002", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "muscle contraction", "id": "GO:0006936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "skeletal muscle thin filament assembly", "id": "GO:0030240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030240", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "skeletal muscle fiber development", "id": "GO:0048741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "striated muscle contraction", "id": "GO:0006941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006941", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "actin nucleation", "id": "GO:0045010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "positive regulation of skeletal muscle fiber development", "id": "GO:0048743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" }, { "name": "myofibril assembly", "id": "GO:0030239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030239", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJ39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ39" }, { "id": "PS51082", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WH2", "eco_id": "ECO_0000259", "start_pos": 528, "end_pos": 547, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 364, "end_pos": 366 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJK1-1", "uniprot_ac": "A0A8V0ZJK1", "uniprot_id": "A0A8V0ZJK1_CHICK", "mass": { "chemical_mass": 41032.0, "monoisotopic_mass": 41032.0 }, "refseq": { "ac": "XP_040535814", "name": "hyaluronan and proteoglycan link protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535814" }, "gene_names": [ { "name": "HAPLN3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" } ] }, { "name": "HAPLN3", "type": "synonym", "evidence": [ { "id": "XP_040535814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535814" } ] } ], "protein_names": [ { "name": "Hyaluronan and proteoglycan link protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1/entry#names_and_taxonomy" } ] }, { "name": "hyaluronan and proteoglycan link protein 3", "type": "synonym", "evidence": [ { "id": "XP_040535814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535814" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052582.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040535814", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535814" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HAPLN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1", "locus": { "chromosome": "10", "start_pos": 13060818, "end_pos": 13055683, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020166", "url": "https://www.ensembl.org/id/ENSGALG00010020166" } ] } } ], "crossref": [ { "id": "A0A8V0ZJK1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03518", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03518", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03519", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03519", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05877", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05877", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415495", "url": "https://www.ncbi.nlm.nih.gov/gene/415495", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415495", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415495", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHPRPNC", "url": "https://omabrowser.org/oma/group/AHPRPNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZD24", "url": "https://www.orthodb.org/?gene=A0A8V0ZD24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDJ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZDJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDK3", "url": "https://www.orthodb.org/?gene=A0A8V0ZDK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJK1", "url": "https://www.orthodb.org/?gene=A0A8V0ZJK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22804", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22804", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22804:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22804:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040535814", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040535814", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZD24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLPLLLKATLLRMVNSYHPFYNGFYYNHVMNDDDNGNEKVVDFNGVRLVVETSKDPIYSFSGVNVTLPCHYHHEPESEAKHKIRIKWSKLRDDYTKEQDVLVAIGKTYMAFGDFQGRAHLHRAGQREASLLISDVRLQDDGKYRCEVIDGLEDASDVVELRLRGIVFPYQPPRGQYSLNFHEAERVCQEQGSLIATFHQLFQAWSEGLDWCNAGWLADGTVHYPIRLPRKPCGGVHLAPGIRSYGPRHRHLHRFDVFCFSSRLRGEVFYLEHPTRMTLEEAKQACQDAGAEIAKVGHLYSAWKFHGLDRCDAGWLADGSVRYPIAKPRPNCGPTEPGVRSFGFPSKGRFGVFCYKER", "length": 359, "header": "tr|A0A8V0ZJK1-1|A0A8V0ZJK1_CHICK Isoform 1 of Hyaluronan and proteoglycan link protein 3 OS=Gallus gallus OX=9031 GN=HAPLN3 PE=1 SV=1 CANONICAL=A0A8V0ZJK1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZD24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1/entry#A0A8V0ZD24-1", "sequence": { "sequence": "MSNPSLQGLREAPWVPGPLCRLRGSLQAPLPALSATLGCQQEKGCGDTGHRDSPMGCGWPRVQPHSPAMLLLPLLLKATLLRMVNSYHPFYNGFYYNHVMNDDDNGNEKVVDFNGVRLVVETSKDPIYSFSGVNVTLPCHYHHEPESEAKHKIRIKWSKLRDDYTKEQDVLVAIGKTYMAFGDFQGRAHLHRAGQREASLLISDVRLQDDGKYRCEVIDGLEDASDVVELRLRGIVFPYQPPRGQYSLNFHEAERVCQEQGSLIATFHQLFQAWSEGLDWCNAGWLADGTVHYPIRLPRKPCGGVHLAPGIRSYGPRHRHLHRFDVFCFSSRLRGEVFYLEHPTRMTLEEAKQACQDAGAEIAKVGHLYSAWKFHGLDRCDAGWLADGSVRYPIAKPRPNCGPTEPGVRSFGFPSKGRFGVFCYKER", "length": 427, "header": "tr|A0A8V0ZD24-1|A0A8V0ZJK1_CHICK Computationally mapped isoform of Hyaluronan and proteoglycan link protein 3 OS=Gallus gallus OX=9031 GN=HAPLN3 PE=1 SV=1 CANONICAL=A0A8V0ZJK1-1" }, "locus": { "chromosome": "10", "start_pos": 13059550, "end_pos": 13056788, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048699.1", "url": "https://www.ensembl.org/id/ENSGALT00010048699.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028776.1", "url": "https://www.ensembl.org/id/ENSGALP00010028776.1" } ] } }, { "isoform_ac": "A0A8V0ZDJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1/entry#A0A8V0ZDJ8-1", "sequence": { "sequence": "MLLLPLLLKATLLRMVNSYHPFYNGFYYNHVMNDDDNGNEKVVDFNGVRLVVETSKDPIYSFSGVNVTLPCHYHHEPESEAKHKIRIKWSKLRDDYTKEQDVLVAIGKTYMAFGDFQGRAHLHRAGQREASLLISDVRLQDDGKYRCEVIDGLEDASDVVELRLRGIVFPYQPPRGQYSLNFHEAERVCQEQGSLIATFHQLFQAWSEGLDWCNAGWLADGTVHYPIRLPRKPCGGVHLAPGIRSYGPRHRHLHRFDVFCFSSRLRGGYPRGCATCWRPMALLSLRMWHAAMLRVMLSPTHCPPDPALLLRGGFLPGTPNQNDAGGSQAGVPGCWR", "length": 336, "header": "tr|A0A8V0ZDJ8-1|A0A8V0ZJK1_CHICK Computationally mapped isoform of Hyaluronan and proteoglycan link protein 3 OS=Gallus gallus OX=9031 GN=HAPLN3 PE=1 SV=1 CANONICAL=A0A8V0ZJK1-1" }, "locus": { "chromosome": "10", "start_pos": 13059348, "end_pos": 13057410, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048706.1", "url": "https://www.ensembl.org/id/ENSGALT00010048706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028780.1", "url": "https://www.ensembl.org/id/ENSGALP00010028780.1" } ] } }, { "isoform_ac": "A0A8V0ZDK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1/entry#A0A8V0ZDK3-1", "sequence": { "sequence": "MLLLPLLLKATLLRMVNSYHPFYNGFYYNHVMNDDDNGNEKVVDFNGVRLVVETSKDPIYSFSGVNVTLPCHYHHEPESEAKHKIRIKWSKLRDDYTKEQDVLVAIGKTYMAFGDFQGRAHLHRAGQREASLLISDVRLQDDGKYRCEVIDGLEDASDVVELRLRGIVFPYQPPRGQYSLNFHEAERVCQEQGSLIATFHQLFQAWSEGLDWCNAGWLADGTVHYPIRLPRKPCGGVHLAPGIRSYGPRHRHLHRFDVFCFSSRLRGEVFYLEHPTRMTLEEAKQACQDAGAEIAKQDAGLEHPALQQGTGSIWATCKDDGPSPSTLVSCP", "length": 331, "header": "tr|A0A8V0ZDK3-1|A0A8V0ZJK1_CHICK Computationally mapped isoform of Hyaluronan and proteoglycan link protein 3 OS=Gallus gallus OX=9031 GN=HAPLN3 PE=1 SV=1 CANONICAL=A0A8V0ZJK1-1" }, "locus": { "chromosome": "10", "start_pos": 13059814, "end_pos": 13057410, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048709.1", "url": "https://www.ensembl.org/id/ENSGALT00010048709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028785.1", "url": "https://www.ensembl.org/id/ENSGALP00010028785.1" } ] } }, { "isoform_ac": "A0A8V0ZJK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1/entry#A0A8V0ZJK1-1", "sequence": { "sequence": "MLLLPLLLKATLLRMVNSYHPFYNGFYYNHVMNDDDNGNEKVVDFNGVRLVVETSKDPIYSFSGVNVTLPCHYHHEPESEAKHKIRIKWSKLRDDYTKEQDVLVAIGKTYMAFGDFQGRAHLHRAGQREASLLISDVRLQDDGKYRCEVIDGLEDASDVVELRLRGIVFPYQPPRGQYSLNFHEAERVCQEQGSLIATFHQLFQAWSEGLDWCNAGWLADGTVHYPIRLPRKPCGGVHLAPGIRSYGPRHRHLHRFDVFCFSSRLRGEVFYLEHPTRMTLEEAKQACQDAGAEIAKVGHLYSAWKFHGLDRCDAGWLADGSVRYPIAKPRPNCGPTEPGVRSFGFPSKGRFGVFCYKER", "length": 359, "header": "tr|A0A8V0ZJK1-1|A0A8V0ZJK1_CHICK Isoform 1 of Hyaluronan and proteoglycan link protein 3 OS=Gallus gallus OX=9031 GN=HAPLN3 PE=1 SV=1 CANONICAL=A0A8V0ZJK1-1" }, "locus": { "chromosome": "10", "start_pos": 13059550, "end_pos": 13057410, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048702.1", "url": "https://www.ensembl.org/id/ENSGALT00010048702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028778.1", "url": "https://www.ensembl.org/id/ENSGALP00010028778.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 336, "start_aa": "Thr", "end_pos": 336, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr336", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415495", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415495", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R305-1", "protein_name": "Hyaluronan and proteoglycan link protein 3", "gene_name": "HAPLN3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPSLYRGSSSIPPHLLPPDGTAAQGPDPPPFTARPAVPRVGGGPRPSLETARVAPSLQAVQDPQICPLPRTWSACSQEHSRRQEPDAWGRLPQAPASPGMPWHCHMHDTMGLPLLVLLLPLCCVSGLPFYNGFYYSNSLNGRNSGNGHGEGIFNGVKLVVETPEETLFSHRGANVTLPCRYRYEPALVSPRPVRIKWWKLSENGTLEQDVLVAIGLRHRSFGDYQGRVHLRRDREQEVSLEIRDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQHPRGRYQFNFHEAQRACEEQDAVVASFEQLFRAWEEGLDWCNAGWLQDASVQYPITQTRHPCGGLSLAPGVRSYGPRHRRRHRYDVFCFAAALRGQVYYLEHPEKLTLAEAKEACQEDGAQIAKVGQLFAAWKFRGLDRCDAGWLADGSARYPVAHPRSNCGSVEPGVRSFGFPDPQSRNYGVYCHRPR", "length": 470 }, "evidence": [ { "id": "A0A8V0ZJK1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJK1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3ICD4-1", "protein_name": "Hyaluronan and proteoglycan link protein 3", "gene_name": "Hapln3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLFLVLLLSLSCVMGLPFSNGFYYSNGLHSRTLGHGYGEGLFNGVKLVVETTEESLFSHRGASVTLPCHYRYEPALASPRHVRVKWWKLSENGSPEQDVLVAIGQRHRSFGNYQGRVQLRQGKQQEVSLELRDLRPEDSGRYRCEVIDGLEDESGLVELELRGVVFPYQPREGRYQLNFHEAQKACQEQDAVVASFEQLFRAWEEGLDWCNAGWLQDASVQYPIALPRQPCGGLGLAPGVRSYGQRHHRLHRYDVFCFTAVLRGWVYYLEHPRKLTLLEAREACQEDGAQISTVGQLFAAWKFRGLDRCDAGWLADGSARYPIVHPRPNCGPPEPGVRTFGFPDPHSRYGVYCYRQR", "length": 359 }, "evidence": [ { "id": "A0A8V0ZJK1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJK1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q80WM5-1", "protein_name": "Hyaluronan and proteoglycan link protein 3", "gene_name": "Hapln3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLLFLVLLSPFPCVLGLPFYNGFYYSNDLSGRTLGNGYGEGLFNGVKLVVETTEESLFSHQGASVTLPCHYHYEPALASPRHVRVKWWKLSENGAPEQDVLVVIGQRHRSFGDYQGRVQLRQDKQQEVSLELRDLRLEDSGRYRCEVIDGLEDESGLVELELRGVVFPYQSREGRYQLNFHEAQQACQEQGAMVATFEQLFRAWEEGLDWCNAGWLQDASVQYPIVLPRQPCGGLGLAPGVRSYGQRHHRLHRYDVFCFAAALKGRVYYLENPKKLTLLEAREACQEDGAQISTVGQLFAAWKFRGLDRCDAGWLADGSARYPIVHPRLNCGPPEPGVRTFGFPDPHTRYGVYCYVQH", "length": 359 }, "evidence": [ { "id": "A0A8V0ZJK1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96S86-1", "protein_name": "Hyaluronan and proteoglycan link protein 3", "gene_name": "HAPLN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLLLLVPLLLLPGSYGLPFYNGFYYSNSANDQNLGNGHGKDLLNGVKLVVETPEETLFTYQGASVILPCRYRYEPALVSPRRVRVKWWKLSENGAPEKDVLVAIGLRHRSFGDYQGRVHLRQDKEHDVSLEIQDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQSPNGRYQFNFHEGQQVCAEQAAVVASFEQLFRAWEEGLDWCNAGWLQDATVQYPIMLPRQPCGGPGLAPGVRSYGPRHRRLHRYDVFCFATALKGRVYYLEHPEKLTLTEAREACQEDDATIAKVGQLFAAWKFHGLDRCDAGWLADGSVRYPVVHPHPNCGPPEPGVRSFGFPDPQSRLYGVYCYRQH", "length": 360 }, "evidence": [ { "id": "A0A8V0ZJK1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" } ], "pmid": "" }, { "name": "perineuronal net", "id": "GO:0072534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072534", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" } ], "pmid": "" }, { "name": "gel phase of interstitial matrix", "id": "GO:0140150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140150", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hyaluronic acid binding", "id": "GO:0005540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 163, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZJK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK1" }, { "id": "PS50963", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50963" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Link", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 262, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 336 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKJ3-1", "uniprot_ac": "A0A8V0ZKJ3", "uniprot_id": "A0A8V0ZKJ3_CHICK", "mass": { "chemical_mass": 61019.0, "monoisotopic_mass": 61019.0 }, "refseq": { "ac": "XP_040562189", "name": "Bardet-Biedl syndrome 4 protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562189" }, "gene_names": [ { "name": "BBS4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ] }, { "name": "BBS4", "type": "synonym", "evidence": [ { "id": "XP_040562189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562189" } ] } ], "protein_names": [ { "name": "BBSome complex member BBS4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3/entry#names_and_taxonomy" } ] }, { "name": "Bardet-Biedl syndrome 4 protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040562189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562189" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040562189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562189" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BBS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3", "locus": { "chromosome": "10", "start_pos": 1748824, "end_pos": 1714097, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021586", "url": "https://www.ensembl.org/id/ENSGALG00010021586" } ] } } ], "crossref": [ { "id": "A0A8V0ZKJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "415318", "url": "https://www.ncbi.nlm.nih.gov/gene/415318", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YCEVAWH", "url": "https://omabrowser.org/oma/group/YCEVAWH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDF3", "url": "https://www.orthodb.org/?gene=A0A8V0ZDF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIY5", "url": "https://www.orthodb.org/?gene=A0A8V0ZIY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKJ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZKJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44186", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44186", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44186:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44186:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620922", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040562189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562189", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPQAGPVSSSPVVAGPPKPHPKRGKKEERRLLCSQSVPEIPVLERRNWFIYLLYVRREYDECKAVIKEQLQESHGRCEYAVYVQALIFRLEGKIQESLELFQTCSILNPRSADNLKQVARSLFLLGKHKAAIEVYNEAAKLDEKDWEISHNLGVCYMYLKHFNKARDQLNNALEMNRHDLTYMMLGKIHLLEGETEKAIEVYKKAVEFSPENTDLLTKLGLIYLQLGDYQKAFEHLGKALTYDQGNYKATLAAGSMMQAHGDYDVALSKYRAVISSMPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRSYEQAVALDKCNPLVNLNYAVLLYNHGDKKGALCQYQEMEKKVTALKENSTLDFDPEMVEVAQKMGTALQVGESQVWTKPAKESRSKQRAAPSGKSASMQQQLGSNQALGQAMSSAAGYGKNMQLPPGAGALATPAKPPSLPLEPEPGPEETSAPAEAKEQRQEKHKSRQAAD", "length": 545, "header": "tr|A0A8V0ZKJ3-1|A0A8V0ZKJ3_CHICK Isoform 1 of BBSome complex member BBS4 OS=Gallus gallus OX=9031 GN=BBS4 PE=3 SV=1 CANONICAL=A0A8V0ZKJ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3/entry#A0A8V0ZDF3-1", "sequence": { "sequence": "MSFFFFFQFVLGKKEERRLLCSQSVPEIPVLERRNWFIYLLYVRREYDECKAVIKEQLQESHGRCEYAVYVQALIFRLEGKIQESLELFQTCSILNPRSADNLKQVARSLFLLGKHKAAIEVYNEAAKLDEKDWEISHNLGVCYMYLKHFNKARDQLNNALEMNRHDLTYMMLGKIHLLEGETEKAIEVYKKAVEFSPENTDLLTKLGLIYLQLGDYQKAFEHLGKALTYDQGNYKATLAAGSMMQAHGDYDVALSKYRAVISSMPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRSYEQAVALDKCNPLVNLNYAVLLYNHGDKKGALCQYQEMEKKVTALKENSTLDFDPEMVEVAQKMGTALQVGESQVWTKPAKESRSKQRAAPSGKSASMQQQLGSNQALGQAMSSAAGYGKNMQLPPGAGALATPAKPPSLPLEPEPGPEETSAPAEAKEQRQEKHKSRQAAD", "length": 531, "header": "tr|A0A8V0ZDF3-1|A0A8V0ZKJ3_CHICK Computationally mapped isoform of BBSome complex member BBS4 OS=Gallus gallus OX=9031 GN=BBS4 PE=3 SV=1 CANONICAL=A0A8V0ZKJ3-1" }, "locus": { "chromosome": "10", "start_pos": 1746449, "end_pos": 1726182, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052400.1", "url": "https://www.ensembl.org/id/ENSGALT00010052400.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031314.1", "url": "https://www.ensembl.org/id/ENSGALP00010031314.1" } ] } }, { "isoform_ac": "A0A8V0ZIY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3/entry#A0A8V0ZIY5-1", "sequence": { "sequence": "MAEPQAGPVSSSPVVAGPPKPHPKRVPEIPVLERRNWFIYLLYVRREYDECKAVIKEQLQESHGRCEYAVYVQALIFRLEGKIQESLELFQTCSILNPRSADNLKQVARSLFLLGKHKAAIEVYNEAAKLDEKDWEISHNLGVCYMYLKHFNKARDQLNNALEMNRHDLTYMMLGKIHLLEGETEKAIEVYKKAVEFSPENTDLLTKLGLIYLQLGDYQKAFEHLGKALTYDQGNYKATLAAGSMMQAHGDYDVALSKYRAVISSMPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRSYEQAVALDKCNPLVNLNYAVLLYNHGDKKGALCQYQEMEKKVTALKENSTLDFDPEKMVEVAQKMGTALQVGESQVWTKPAKESRSKQRAAPSGKSASMQQQLGSNQALGQAMSSAAGYGKNMQLPPGAGALATPAKPPSLPLEPEPGPEETSAPAEAKEQRQEKHKSRQAAD", "length": 533, "header": "tr|A0A8V0ZIY5-1|A0A8V0ZKJ3_CHICK Computationally mapped isoform of BBSome complex member BBS4 OS=Gallus gallus OX=9031 GN=BBS4 PE=3 SV=1 CANONICAL=A0A8V0ZKJ3-1" }, "locus": { "chromosome": "10", "start_pos": 1746449, "end_pos": 1714100, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052411.1", "url": "https://www.ensembl.org/id/ENSGALT00010052411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031322.1", "url": "https://www.ensembl.org/id/ENSGALP00010031322.1" } ] } }, { "isoform_ac": "A0A8V0ZKJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3/entry#A0A8V0ZKJ3-1", "sequence": { "sequence": "MAEPQAGPVSSSPVVAGPPKPHPKRGKKEERRLLCSQSVPEIPVLERRNWFIYLLYVRREYDECKAVIKEQLQESHGRCEYAVYVQALIFRLEGKIQESLELFQTCSILNPRSADNLKQVARSLFLLGKHKAAIEVYNEAAKLDEKDWEISHNLGVCYMYLKHFNKARDQLNNALEMNRHDLTYMMLGKIHLLEGETEKAIEVYKKAVEFSPENTDLLTKLGLIYLQLGDYQKAFEHLGKALTYDQGNYKATLAAGSMMQAHGDYDVALSKYRAVISSMPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRSYEQAVALDKCNPLVNLNYAVLLYNHGDKKGALCQYQEMEKKVTALKENSTLDFDPEMVEVAQKMGTALQVGESQVWTKPAKESRSKQRAAPSGKSASMQQQLGSNQALGQAMSSAAGYGKNMQLPPGAGALATPAKPPSLPLEPEPGPEETSAPAEAKEQRQEKHKSRQAAD", "length": 545, "header": "tr|A0A8V0ZKJ3-1|A0A8V0ZKJ3_CHICK Isoform 1 of BBSome complex member BBS4 OS=Gallus gallus OX=9031 GN=BBS4 PE=3 SV=1 CANONICAL=A0A8V0ZKJ3-1" }, "locus": { "chromosome": "10", "start_pos": 1746449, "end_pos": 1714100, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052407.1", "url": "https://www.ensembl.org/id/ENSGALT00010052407.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031319.1", "url": "https://www.ensembl.org/id/ENSGALP00010031319.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 506, "start_aa": "Thr", "end_pos": 506, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr506", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5620922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620922", "resource": "Reactome", "description": "BBSome-mediated cargo-targeting to cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AKX1-1", "protein_name": "BBSome complex member BBS4", "gene_name": "BBS4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEERLATRTQFLASAESQKPQLKKAPEFPILEKQNWLIHLHYIRKDYEACKAIIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAILSPQCADNLKQVARSLFLLGKHKAATEVYNEAAKLNQKDWEICHNLGVCYIYLKQFDKAQDQLHNALHLNRHDLTYIMLGKIHLLEGDLDKAIEIYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFEVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDLENAKRAYAEAVRLDKCNPLVNLNYAVLLYNQGEKRGALAQYQEMEKKVNLLKDSSSLEFDPEMVEMAQKLGAALQAGEALVWTKPVKDPKSKHRTPSTSKTTSVQQPLGSNQALGQAMSSAATYRKLPSGAGGTPQPTKPPSLPLEPEPTVEAQPTGASAQIREKQV", "length": 521 }, "evidence": [ { "id": "A0A8V0ZKJ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKJ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2N4D2-1", "protein_name": "BBSome complex member BBS4", "gene_name": "Bbs4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEEKLRMKTQVPESQKPRPKKALEFPIVERLNWLIHLHYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQCADNLKQVARSLFLLGKHKAATEVYNEAAKLNQKDWEICHNLGVCYTYLKQFSKAQDQLHSALQLNKHDLTYIMLGKIHLLEGDLDKAIEIYKKAVEFSPENTDLLTTLGLLYLQLGVYQKAFEHLGNALTYDPANYKAILAAGSMMQTHGDFDVALTKYRVVACAIPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDTENAKRAYAEAVRLDKCNPLVNLNYAVLLYNQGDKKGALAQYQEMEKKVNFLKDNSTLEFDSEMVEMAQKLGAALQVGEALVWTKPVKDPKSKHRTNSASKSAALQQPLGSNQALGQAMSSAAAYRKLPSGAVGAQLTKPPSLPLEPEPESTVEASPTEASEQKKEK", "length": 517 }, "evidence": [ { "id": "A0A8V0ZKJ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKJ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6AHB5-1", "protein_name": "BBSome complex member BBS4", "gene_name": "Bbs4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLERYSFRRCTLACSDSVDLFHLLGSTEMPMKTQVPASIESQKPRPKKAPEFPIVEKLNWLIHLYYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQCADNLKQVARSLFLLGKHKAATEVYNEAAKLNQKDWEICHNLGVCYTYLKQFSKAQDQLHSALQLNKHDLTYIMLGKIHLLQGDLDKAIEIYKKAVEFSPENTELLTTLGLLYLQLGVYQKAFEHLGNALTYDPANYKAILAAGSMMQTHGDFDVALTKYRVVACAIPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYVEAVRLDKCNPLVNLNYAVLLYNQGEKKGALAQYQEMEKKVHFLKDNNPLEFDSEMVEMAQKLGAALQVGEALVWTKPVKDPKSKHRTNSGSKSATLQQPLGSFQALGQAMSSAAAHRKIPSGAVGAQLTKPPSLPLEPEPEPTVEASPTEASEQNKEK", "length": 544 }, "evidence": [ { "id": "A0A8V0ZKJ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKJ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1Z8E9-1", "protein_name": "BBSome complex member BBS4 homolog", "gene_name": "BBS4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYEPGTEQINCNGRLIELPTLEVVRPAPKMPSDANIDWLLHIYFTRREFTRCRRLIERELNRHLNPEYLYFVQGLIDREEGNHIEALRHLQKSAELNPRNIETYKEIGRTLYIMGRFSQALGVFREAEQRSSRQDHEIYHYLGELLYRAATTQSQKDVASQQQDEARTYFELAVQSGRKLESYVRLAELYRKDKQYQKAIEILENCLHLTPENSEVLIEISVLYLKINETQKAHDRLAEVVSIERKCSPKGLLAFGAILQSRNDIDGALSKYSQIANAEPEIAELWNNIGLCFFKKQKFIVAISSLRKSVWLSPLNYNALYNLSLIYIASEQYASAFHTLAAAINLRKDNAECYMLLGLCLRKLDDMENAFVALERASSMATGQQGAGRNPLVVLNFALFCYETGRLALSTEQYNRFMSQAQDLLLPTEYKFQATKLKSLLRISNQGNGILLDSADMGESDLGHNRATELLPDELPLEVNAVVSQN", "length": 486 }, "evidence": [ { "id": "A0A8V0ZKJ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKJ3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "E7EXH4-1", "protein_name": "BBSome complex member BBS4", "gene_name": "bbs4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADDAMRTDVQLPVATELKKPRLKKAPELPILEKRNWLIHLHYIRKDYETCKAIVKEQLHETQGMCEYAVYVQALIMRLEGKIQESLELFQSCAIINPTSSDNLKQVARSLFLLGKHKAAIEVYNEAARLNQKDWEISHNLGVCYIYTKDFRSAEEQLNLALQLNKHDLTYMMLGKIHLLQGDTEKAIDVYKSAVEFSPENTELLTTLGLLYMQLGKYQKAFEHLGNALTYDPNNFKAILAAGSMMQTHGDYDVAMNKYRVAAYAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLSPFDWKILYNLGLVHLTMQQFASAFHFLSAAINLRPRMSELYMLLAVALTNLDDAENARRSYEQAVQIDESSPLVNLNFAVFLYNQGDKKAALLQYQEMERKVNTQLENSSNTEFDPELVEMAQKLGGALQAGENLYWSKPGKDGKTSQRSSSSKPSGSQQPLGTNQALGQAMSSAAGFSKSMQISAEADVSRAPSPPAGDPEDEDEVEDAAGPAKPKDKKGRAKPVAE", "length": 528 }, "evidence": [ { "id": "A0A8V0ZKJ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKJ3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1JQ97-1", "protein_name": "BBSome complex member BBS4", "gene_name": "BBS4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEEKLSARTQLPVSAESQKPVLKKAPEFPILEKQNWLIHLYYIQKDYEACKAVIKEQLQETHGLCEYAIYVQALIFRLEGNIQESLRLFQMCAFLSPQCADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEICHNLGVCYIYLKQFDKAQDQLHNALHLNRHDLTYIMLGKIFLLKGDLDKAIEIYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNTLTYDPTNYKAILAAGSMMQTHGDFDVALTKYKVVACAVIESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPLDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDSENAKRAYEEAVRLDKCNPLVNLNYAVLLYNQGEKRDALAQYQEMEKKVNLLKYSSSLEFDPEMVEVAQKLGAALQVGEALVWTKPVKDPKSKHQTASTSKAAGFQQPLGSNQALGQAMSSAATCRKLSSGAGGTSQLTKPPSLPLEPEPTVEAQPTEASAQTREK", "length": 519 }, "evidence": [ { "id": "A0A8V0ZKJ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKJ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8C1Z7-1", "protein_name": "BBSome complex member BBS4", "gene_name": "Bbs4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEVKLGMKTQVPASVESQKPRSKKAPDFPIVEKQNWLIHLHYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQCADNLKQVARSLFLLGKHKAATEVYNEAAKLNQKDWEICHNLGVCYTYLKQFNKAQDQLHSALQLNKHDLTYIMLGKIHLLQGDLDKAIEIYKKAVEFSPENTELLTTLGLLYLQLGVYQKAFEHLGNALTYDPANYKAILAAGSMMQTHGDFDVALTKYRVVACAIPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENARRAYVEAVRLDKCNPLVNLNYAVLLYNQGEKKSALAQYQEMEKKVNFLKDNSPLEFDSEMVEMAQKLGAALQVGEALVWTKPVKDPKTKHRTNSGSKSATLQQPLGSIQALGQAMSSAAAYRKILSGAVGAQLPKPPSLPLEPEPEPTVEASPTEASEQKKEK", "length": 520 }, "evidence": [ { "id": "A0A8V0ZKJ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKJ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96RK4-1", "protein_name": "BBSome complex member BBS4", "gene_name": "BBS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEERVATRTQFPVSTESQKPRQKKAPEFPILEKQNWLIHLHYIRKDYEACKAVIKEQLQETQGLCEYAIYVQALIFRLEGNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLLYNQGEKKNALAQYQEMEKKVSLLKDNSSLEFDSEMVEMAQKLGAALQVGEALVWTKPVKDPKSKHQTTSTSKPASFQQPLGSNQALGQAMSSAAAYRTLPSGAGGTSQFTKPPSLPLEPEPAVESSPTETSEQIREK", "length": 519 }, "evidence": [ { "id": "A0A8V0ZKJ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKJ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "photoreceptor connecting cilium", "id": "GO:0032391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032391", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "BBSome", "id": "GO:0034464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034464", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "pericentriolar material", "id": "GO:0000242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "beta-tubulin binding", "id": "GO:0048487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048487", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "alpha-tubulin binding", "id": "GO:0043014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043014", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "dynactin binding", "id": "GO:0034452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034452", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "mitotic cytokinesis", "id": "GO:0000281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "centrosome cycle", "id": "GO:0007098", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007098", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "maintenance of protein location in nucleus", "id": "GO:0051457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "protein localization to centrosome", "id": "GO:0071539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "negative regulation of appetite by leptin-mediated signaling pathway", "id": "GO:0038108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038108", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "regulation of cilium beat frequency involved in ciliary motility", "id": "GO:0060296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" }, { "name": "microtubule anchoring at centrosome", "id": "GO:0034454", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034454", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 506 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 421, "end_pos": 423 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKW3-1", "uniprot_ac": "A0A8V0ZKW3", "uniprot_id": "A0A8V0ZKW3_CHICK", "mass": { "chemical_mass": 29402.0, "monoisotopic_mass": 29402.0 }, "refseq": { "ac": "XP_040530616", "name": "ribonuclease P protein subunit p30", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040530616" }, "gene_names": [ { "name": "RPP30", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ] }, { "name": "RPP30", "type": "synonym", "evidence": [ { "id": "XP_040530616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040530616" } ] } ], "protein_names": [ { "name": "Ribonuclease P protein subunit p30", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3/entry#names_and_taxonomy" } ] }, { "name": "RNase P subunit 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3/entry#names_and_taxonomy" } ] }, { "name": "ribonuclease P protein subunit p30", "type": "synonym", "evidence": [ { "id": "XP_040530616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040530616" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052578.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040530616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040530616" } ] }, { "annotation": "Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZDG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG1#function" }, { "database": "UniProtKB", "id": "ARBA00053284", "url": "https://www.uniprot.org/uniprotkb/ARBA00053284#function" }, { "database": "UniProtKB", "id": "A0A8V0ZEH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEH2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPP30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3", "locus": { "chromosome": "6", "start_pos": 20401533, "end_pos": 20384007, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020481", "url": "https://www.ensembl.org/id/ENSGALG00010020481" } ] } } ], "crossref": [ { "id": "A0A8V0ZKW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "423795", "url": "https://www.ncbi.nlm.nih.gov/gene/423795", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CYGPGIT", "url": "https://omabrowser.org/oma/group/CYGPGIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDG1", "url": "https://www.orthodb.org/?gene=A0A8V0ZDG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEH2", "url": "https://www.orthodb.org/?gene=A0A8V0ZEH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKW3", "url": "https://www.orthodb.org/?gene=A0A8V0ZKW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13031", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13031", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13031:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13031:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01876", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01876", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040530616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040530616", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGFADLNVPQGADRKAVQSLLEAAAHLGYSAVALNHIIDFKEKKQEIAKPVSPSELFPSLPIVQGTSKRLKVLTRLTLVVSDPSHCNLLRSTSTNIRLYDIIAVFPKTEKLFHIACTTLDVDLVCINVTEKLPFYFRRPPVNMAIDRGIYFELLYTPAIKDSTMRRYTISNAISLMQICKGKNIVISSAAERPLELRGPYDVANLGLLFGLSEGEAKAAVSTNCRATILHGETRKSACGVVYTVKKLHKVEEEETVPACKKAKTQA", "length": 267, "header": "tr|A0A8V0ZKW3-1|A0A8V0ZKW3_CHICK Isoform 1 of Ribonuclease P protein subunit p30 OS=Gallus gallus OX=9031 GN=RPP30 PE=1 SV=1 CANONICAL=A0A8V0ZKW3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3/entry#A0A8V0ZDG1-1", "sequence": { "sequence": "VAVHLRVYPSTGCAHPCPHHCQSVRTRCQSWVVLRKKFVLFRHIFVGYSAVALNHIIDFKEKKQEIAKPVSPSELFPSLPIVQGTSKRLKVLTRLTLVVSDPSHCNLLRSTSTNIRLYDIIAVFPKTEKLFHIACTTLDVDLVCINVTEKLPFYFRRPPVNMAIDRGIYFELLYTPAIKDSTMRRYTISNAISLMQICKGKNIVISSAAERPLELRGPYDVANLGLLFGLSEGEAKAAVSTNCRATILHGETRKSACGVVYTVKKLHKVEEEETVPACKKAKTQA", "length": 285, "header": "tr|A0A8V0ZDG1-1|A0A8V0ZKW3_CHICK Computationally mapped isoform of Ribonuclease P protein subunit p30 OS=Gallus gallus OX=9031 GN=RPP30 PE=1 SV=1 CANONICAL=A0A8V0ZKW3-1" }, "locus": { "chromosome": "6", "start_pos": 20399763, "end_pos": 20384800, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049510.1", "url": "https://www.ensembl.org/id/ENSGALT00010049510.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029256.1", "url": "https://www.ensembl.org/id/ENSGALP00010029256.1" } ] } }, { "isoform_ac": "A0A8V0ZEH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3/entry#A0A8V0ZEH2-1", "sequence": { "sequence": "MAGFADLNVPQGADRKAVQSLLEAAAHLGYSAVALNHIIDFKEKKQGTSKRLKVLTRLTLVVSDPSHCNLLRSTSTNIRLYDIIAVFPKTEKLFHIACTTLDVDLVCINVTEKLPFYFRRPPVNMAIDRGIYFELLYTPAIKDSTMRRYTISNAISLMQICKGKNIVISSAAERPLELRGPYDVANLGLLFGLSEGEAKAAVSTNCRATILHGETRKSACGVVYTVKKLHKVEEEETVPACKKAKTQA", "length": 248, "header": "tr|A0A8V0ZEH2-1|A0A8V0ZKW3_CHICK Computationally mapped isoform of Ribonuclease P protein subunit p30 OS=Gallus gallus OX=9031 GN=RPP30 PE=1 SV=1 CANONICAL=A0A8V0ZKW3-1" }, "locus": { "chromosome": "6", "start_pos": 20399763, "end_pos": 20384214, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049505.1", "url": "https://www.ensembl.org/id/ENSGALT00010049505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029253.1", "url": "https://www.ensembl.org/id/ENSGALP00010029253.1" } ] } }, { "isoform_ac": "A0A8V0ZKW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3/entry#A0A8V0ZKW3-1", "sequence": { "sequence": "MAGFADLNVPQGADRKAVQSLLEAAAHLGYSAVALNHIIDFKEKKQEIAKPVSPSELFPSLPIVQGTSKRLKVLTRLTLVVSDPSHCNLLRSTSTNIRLYDIIAVFPKTEKLFHIACTTLDVDLVCINVTEKLPFYFRRPPVNMAIDRGIYFELLYTPAIKDSTMRRYTISNAISLMQICKGKNIVISSAAERPLELRGPYDVANLGLLFGLSEGEAKAAVSTNCRATILHGETRKSACGVVYTVKKLHKVEEEETVPACKKAKTQA", "length": 267, "header": "tr|A0A8V0ZKW3-1|A0A8V0ZKW3_CHICK Isoform 1 of Ribonuclease P protein subunit p30 OS=Gallus gallus OX=9031 GN=RPP30 PE=1 SV=1 CANONICAL=A0A8V0ZKW3-1" }, "locus": { "chromosome": "6", "start_pos": 20399763, "end_pos": 20384214, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049516.1", "url": "https://www.ensembl.org/id/ENSGALT00010049516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029260.1", "url": "https://www.ensembl.org/id/ENSGALP00010029260.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "G3H3V1-1", "protein_name": "Ribonuclease P protein subunit p30", "gene_name": "Rpp30", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAFADLDLRAGSDLKALRGLVETAAHLGYSVVAINHIVDFKEKKQEIEKPVAVSELFTTLPIVQGKSRPIKILTRLTIIVTDPSHCNVLRATSSRVRLYDIVAVFPKTEKLFHVACTHLDVDLVCITVTEKLPFYFKRPPINVAIDRGLGFELVYGPAIRDATMRRYTISNALNLMQICRGKNVILSSAAERPLEIRGPYDVANLGLLFGLSENEAKAAVSTNCRAVFLHGETRKTAFGIISTVKKPRPSEVDDDCLPACKKAKCEG", "length": 268 }, "evidence": [ { "id": "A0A8V0ZKW3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKW3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O88796-1", "protein_name": "Ribonuclease P protein subunit p30", "gene_name": "Rpp30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAFADLDLRAGSDLKALRGLVETAAHLGYSVVAINHIVDFKEKKREIEKPIAVSELFTTLPIVQGKSRPIKILTRLTIIVTDPAHCNVLRATSSRVRLYDIVAVFPKTEKLFHVACTHLDVDLVCITVTEKLPFYFKRPPVNVAIERGLGFELVYGPAIRDATMRRYTISNALNLMQICKGKNVILSSAAERPLEIRGPYDVANLGLLFGLSENDGKAAVSTNCRAVFLHGETRKTAFGIISTVKKPRPSEADDESLPVCKKAKCEG", "length": 268 }, "evidence": [ { "id": "A0A8V0ZKW3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKW3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P38786-1", "protein_name": "Ribonuclease P/MRP protein subunit RPP1", "gene_name": "RPP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLVDLNVPWPQNSYADKVTSQAVNNLIKTLSTLHMLGYTHIAINFTVNHSEKFPNDVKLLNPIDIKRRFGELMDRTGLKLYSRITLIIDDPSKGQSLSKISQAFDIVAALPISEKGLTLSTTNLDIDLLTFQYGSRLPTFLKHKSICSCVNRGVKLEIVYGYALRDVQARRQFVSNVRSVIRSSRSRGIVIGSGAMSPLECRNILGVTSLIKNLGLPSDRCSKAMGDLASLVLLNGRLRNKSHKQTIVTGGGSGNGDDVVNDVQGIDDVQTIKVVKRSMDAEQLGHASKRHKP", "length": 293 }, "evidence": [ { "id": "A0A8V0ZKW3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKW3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P78346-1", "protein_name": "Ribonuclease P protein subunit p30", "gene_name": "RPP30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVFADLDLRAGSDLKALRGLVETAAHLGYSVVAINHIVDFKEKKQEIEKPVAVSELFTTLPIVQGKSRPIKILTRLTIIVSDPSHCNVLRATSSRARLYDVVAVFPKTEKLFHIACTHLDVDLVCITVTEKLPFYFKRPPINVAIDRGLAFELVYSPAIKDSTMRRYTISSALNLMQICKGKNVIISSAAERPLEIRGPYDVANLGLLFGLSESDAKAAVSTNCRAALLHGETRKTAFGIISTVKKPRPSEGDEDCLPASKKAKCEG", "length": 268 }, "evidence": [ { "id": "A0A8V0ZKW3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKW3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3SZ21-1", "protein_name": "Ribonuclease P protein subunit p30", "gene_name": "RPP30", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVFADLDLRAGSDLKALRGLVENAAHLGYSVVAINHVVEFKEKKQEIEKPVAVSELFTTLPIVQGKSKPIKILTRLTIIVSDPSHCNVLRATSSRVRLYDIVAVFPKTEKLFHVACTHLDVDLVCITVTEKLPFYFKRPPINVAIDRGVGFELLYSPAIKDSTMRRYTISNALNLMQVCKGKNVIISSAAERPLEIRGPYDVANLGLLFGLSESDAKAAVSTNCRAVLLHGETRKTAFGIISTVKKPRTSEADDDSLPACKKAKCES", "length": 268 }, "evidence": [ { "id": "A0A8V0ZKW3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKW3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9VPM0-1", "protein_name": "RNaseP protein p30, isoform B", "gene_name": "Rpp30", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEQTRPFYDFSIPYNKDDSVLRALLNELVETGYKTVAIDQSFDHSKKDPGKRGSEMFPEPHKIEHLRKEFQDKLRILQRITILYVDVNVAHAMSVSHNLRKFNLIAGQPKTDAALTHCCTAFNGDLITFDPVAGSRLLVNRKAYQVAVRRGMFFEIKYAPSICDSNNRKDMIKIAQNYCTKGKSKNVIFSSGAAHEFQLRGPYDVANLAFIFGLSEDQGKNAVDGHCRELFLKAEARRLGKTIMFLKGNGPIIYSDSSEDEKSTEDEMKGLKPQIGKADAFEVKDGTEHAIKRLKVA", "length": 297 }, "evidence": [ { "id": "A0A8V0ZKW3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKW3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolar ribonuclease P complex", "id": "GO:0005655", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005655", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" }, { "name": "ribonuclease MRP complex", "id": "GO:0000172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000172", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" }, { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" }, { "name": "ribonuclease P RNA binding", "id": "GO:0033204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" }, { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" }, { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJ27-1", "uniprot_ac": "A0A8V0ZJ27", "uniprot_id": "A0A8V0ZJ27_CHICK", "mass": { "chemical_mass": 151763.0, "monoisotopic_mass": 151763.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Castor zinc finger 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27", "locus": {} } ], "crossref": [ { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDK5", "url": "https://www.orthodb.org/?gene=A0A8V0ZDK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ27", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKP4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKQ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZKQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKQ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZKQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12451", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12451", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12451:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12451:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26743", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26743", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZDK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLCFPSAILSPSAVLSGSLPAGFPFSVGSCRPKGEMQILPMSLLPQRRGNWGWGDKGMGWLAESWQQSWQEDWGADSLRHRHRWDGEMASGRVGFVDHGRAERTICTDATSGKPTMAAKRKGGLKLNAICAKLSRQVVFDHGGAEQARADKGPQRESSNKDLPQPGTKEPGTEFSDGLSHVQKIEEDKRREVIEKWVNGEYEEPLLGRAEGKECRGAEGAEVPPEGVYMVQPKGCSDEEDNGDEADALRGSQDGTFLDDRDSDGAASKDDAYRASSEAASKLGTTSGEASSLRDYAATTMNEFLGMFGYDDQNMRDELARKISFDKLNAATSEATAAAASLPGEDAMSKRARFSKYEEYIRKLKAGEQLSWPMHLAKSEELGSKLGKEASSVLAQPIRLPGPDASMLTETKATILPLPSPSSSQMQGLMSRASKYDFFIQKLKTGESIRPQNGNTYKKASKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRNIQKLTQVKAPTPSLAPTPLASTPSSAPMAGPEQAVSLPFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPTVSEDVNIYQKYIARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTVECQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGVLGLPASLLGPKDNEQEESSNDDLIDFSAMSSKNSSLSASPTSQQSSVSLIVPAAPSSAAELASSQVSKPANSMTPATKISGLLSQALPSNIPLALALSNSALPGAAGSFFPIIPSRVSTPLPASSANLMTAGSSGANPTSSAPTDSSSQAVSGSGEPSATSSPAPVASIMERISASKGLISPMMARLAAAALKPSVALEAGNGQAAAPGRFNPVQVKQEPAEAMGSSSAAGQESLQEHSLDLSVKDHGNESNGHTVSANSSLLSSLMNKMSKTSASLGNLLNIKTEGDGSQAGAGEPTQYLGKAVKALVQEKLSEPWKMYLRRFGTKDFCDAQCDFLHKVHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAVKSNSESPFSTATDSKASLGPSSPSATSATMASAPALDVPTPSPATVPSAPTLLAWKQLASTIPQMPQIPASVPNLATSPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRPGCYFVTNITTKLPWHVKKT", "length": 1399, "header": "tr|A0A8V0ZJ27-1|A0A8V0ZJ27_CHICK Isoform 1 of Castor zinc finger 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZJ27-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27/entry#A0A8V0ZDK5-1", "sequence": { "sequence": "MKVDYLSEFGFRLSYYAERTICTDATSGKPTMAAKRKGGLKLNAICAKLSRQVVFDHGGAEQARADKGPQRESSNKDLPQPGTKEPGTEFSDGLSHVQKIEEDKRREVIEKWVNGEYEEPLLGRAEGKECRGAEGAEVPPEGVYMVQPKGCSDEEDNGDEADALRGSQDGTFLDDRDSDGAASKDDAYRASSEAASKLGTTSGEASSLRDYAATTMNEFLGMFGYDDQNMRDELARKISFDKLNAATSEATAAAASLPGEDAMSKRARFSKYEEYIRKLKAGEQLSWPMHLAKSEELGSKLGKEASSVLAQPIRLPGPDASMLTETKATILPLPSPSSSQMQGLMSRASKYDFFIQKLKTGESIRPQNGNTYKKASKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRNIQKLTQVKAPTPSLAPTPLASTPSSAPMAGPEQAVSLPFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPTVSEDVNIYQKYIARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTVECQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGVLGLPASLLGPKDNEQEESSNDDLIDFSAMSSKNSSLSASPTSQQSSVSLIVPAAPSSAAELASSQVSKPANSMTPATKISGLLSQALPSNIPLALALSNSALPGAAGSFFPIIPSRVSTPLPASSANLMTAGSSGANPTSSAPTDSSSQAVSGSGEPSATSSPAPVASIMERISASKGLISPMMARLAAAALKPSVALEAGNGQAAAPGRFNPVQVKQEPAEAMGSSSAAGQESLQEHSLDLSVKDHGNESNGHTVSANSSLLSSLMNKMSKTSASLGNLLNIKTEGDGSQAGAGEPTQYLGKAVKALVQEKLSEPWKMYLRRFGTKDFCDAQCDFLHKVHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAVKSNSESPFSTATDSKASLGPSSPSATSATMASAPALDVPTPSPATVPSAPTLLAWKQLASTIPQMPQIPASVPNLATSPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQVRVIQSISS", "length": 1289, "header": "tr|A0A8V0ZDK5-1|A0A8V0ZJ27_CHICK Computationally mapped isoform of Castor zinc finger 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZJ27-1" }, "locus": { "chromosome": "21", "start_pos": 3894141, "end_pos": 3834432, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052458.1", "url": "https://www.ensembl.org/id/ENSGALT00010052458.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031365.1", "url": "https://www.ensembl.org/id/ENSGALP00010031365.1" } ] } }, { "isoform_ac": "A0A8V0ZJ27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27/entry#A0A8V0ZJ27-1", "sequence": { "sequence": "MMLCFPSAILSPSAVLSGSLPAGFPFSVGSCRPKGEMQILPMSLLPQRRGNWGWGDKGMGWLAESWQQSWQEDWGADSLRHRHRWDGEMASGRVGFVDHGRAERTICTDATSGKPTMAAKRKGGLKLNAICAKLSRQVVFDHGGAEQARADKGPQRESSNKDLPQPGTKEPGTEFSDGLSHVQKIEEDKRREVIEKWVNGEYEEPLLGRAEGKECRGAEGAEVPPEGVYMVQPKGCSDEEDNGDEADALRGSQDGTFLDDRDSDGAASKDDAYRASSEAASKLGTTSGEASSLRDYAATTMNEFLGMFGYDDQNMRDELARKISFDKLNAATSEATAAAASLPGEDAMSKRARFSKYEEYIRKLKAGEQLSWPMHLAKSEELGSKLGKEASSVLAQPIRLPGPDASMLTETKATILPLPSPSSSQMQGLMSRASKYDFFIQKLKTGESIRPQNGNTYKKASKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRNIQKLTQVKAPTPSLAPTPLASTPSSAPMAGPEQAVSLPFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPTVSEDVNIYQKYIARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTVECQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGVLGLPASLLGPKDNEQEESSNDDLIDFSAMSSKNSSLSASPTSQQSSVSLIVPAAPSSAAELASSQVSKPANSMTPATKISGLLSQALPSNIPLALALSNSALPGAAGSFFPIIPSRVSTPLPASSANLMTAGSSGANPTSSAPTDSSSQAVSGSGEPSATSSPAPVASIMERISASKGLISPMMARLAAAALKPSVALEAGNGQAAAPGRFNPVQVKQEPAEAMGSSSAAGQESLQEHSLDLSVKDHGNESNGHTVSANSSLLSSLMNKMSKTSASLGNLLNIKTEGDGSQAGAGEPTQYLGKAVKALVQEKLSEPWKMYLRRFGTKDFCDAQCDFLHKVHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAVKSNSESPFSTATDSKASLGPSSPSATSATMASAPALDVPTPSPATVPSAPTLLAWKQLASTIPQMPQIPASVPNLATSPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRPGCYFVTNITTKLPWHVKKT", "length": 1399, "header": "tr|A0A8V0ZJ27-1|A0A8V0ZJ27_CHICK Isoform 1 of Castor zinc finger 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZJ27-1" }, "locus": { "chromosome": "21", "start_pos": 3868540, "end_pos": 3833843, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052455.1", "url": "https://www.ensembl.org/id/ENSGALT00010052455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031362.1", "url": "https://www.ensembl.org/id/ENSGALP00010031362.1" } ] } }, { "isoform_ac": "A0A8V0ZKP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27/entry#A0A8V0ZKP4-1", "sequence": { "sequence": "MAERTICTDATSGKPTMAAKRKGGLKLNAICAKLSRQVVFDHGGAEQARADKGPQRESSNKDLPQPGTKEPGTEFSDGLSHVQKIEEDKRREVIEKWVNGEYEEPLLGRAEGKECRGAEGAEVPPEGVYMVQPKGCSDEEDNGDEADALRGSQDGTFLDDRDSDGAASKDDAYRASSEAASKLGTTSGEASSLRDYAATTMNEFLGMFGYDDQNMRDELARKISFDKLNAATSEATAAAASLPGEDAMSKRARFSKYEEYIRKLKAGEQLSWPMHLAKSEELGSKLGKEASSVLAQPIRLPGPDASMLTETKATILPLPSPSSSQMQGLMSRASKYDFFIQKLKTGESIRPQNGNTYKKASKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRNIQKLTQVKAPTPSLAPTPLASTPSSAPMAGPEQAVSLPFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPTVSEDVNIYQKYIARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTVECQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGVLGLPASLLGPKDNEQEESSNDDLIDFSAMSSKNSSLSASPTSQQSSVSLIVPAAPSSAAELASSQVSKPANSMTPATKISGLLSQALPSNIPLALALSNSALPGAAGSFFPIIPSRVSTPLPASSANLMTAGSSGANPTSSAPTDSSSQAVSGSGEPSATSSPAPVASIMERISASKGLISPMMARLAAAALKPSVALEAGNGQAAAPGRFNPVQVKQEPAEAMGSSSAAGQESLQEHSLDLSVKDHGNESNGHTVSANSSLLSSLMNKMSKTSASLGNLLNIKTEGDGSQAGAGEPTQYLGKAVKALVQEKLSEPWKMYLRRFGTKDFCDAQCDFLHKVHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAVKSNSESPFSTATDSKASLGPSSPSATSATMASAPALDVPTPSPATVPSAPTLLAWKQLASTIPQMPQIPASVPNLATSPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRPGCYFVTNITTKLPWHVKKT", 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"MAAKRKGGLKLNAICAKLSRQVVFDHGGAEQARADKGPQRESSNKDLPQPGTKEPGTEFSDGLSHVQKIEEDKRREVIEKWVNGEYEEPLLGRAEGKECRGAEGAEVPPEGVYMVQPKGCSDEEDNGDEADALRGSQDGTFLDDRDSDGAASKDDAYRASSEAASKLGTTSGEASSLRDYAATTMNEFLGMFGYDDQNMRDELARKISFDKLNAATSEATAAAASLPGEDAMSKRARFSKYEEYIRKLKAGEQLSWPMHLAKSEELGSKLGKEASSVLAQPIRLPGPDASMLTETKATILPLPSPSSSQMQGLMSRASKYDFFIQKLKTGESIRPQNGNTYKKASKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRNIQKLTQVKAPTPSLAPTPLASTPSSAPMAGPEQAVSLPFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPTVSEDVNIYQKYIARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTVECQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGVLGLPASLLGPKDNEQEESSNDDLIDFSAMSSKNSSLSASPTSQQSSVSLIVPAAPSSAAELASSQVSKPANSMTPATKISGLLSQALPSNIPLALALSNSALPGAAGSFFPIIPSRVSTPLPASSANLMTAGSSGANPTSSAPTDSSSQAVSGSGEPSATSSPAPVASIMERISASKGLISPMMARLAAAALKPSVALEAGNGQAAAPGRFNPVQVKQEPAEAMGSSSAAGQESLQEHSLDLSVKDHGNESNGHTVSANSSLLSSLMNKMSKTSASLGNLLNIKTEGDGSQAGAGEPTQYLGKAVKALVQEKLSEPWKMYLRRFGTKDFCDAQCDFLHKVHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAVKSNSESPFSTATDSKASLGPSSPSATSATMASAPALDVPTPSPATVPSAPTLLAWKQLASTIPQMPQIPASVPNLATSPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQVRVIQSISS", "length": 1258, "header": "tr|A0A8V0ZKQ0-1|A0A8V0ZKQ0_CHICK Computationally mapped isoform of Castor zinc finger 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZJ27-1" }, "locus": { "chromosome": "21", "start_pos": 3865939, "end_pos": 3834432, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052470.1", "url": "https://www.ensembl.org/id/ENSGALT00010052470.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031377.1", "url": "https://www.ensembl.org/id/ENSGALP00010031377.1" } ] } }, { "isoform_ac": "A0A8V0ZKQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27/entry#A0A8V0ZKQ6-1", "sequence": { "sequence": "MAHARCSLHPKHTHISPDLESHPKQPQVQGKETSPSEEKPSNSLSSPETASETKILTSLPALYTGMDLEACDFSMQAERTICTDATSGKPTMAAKRKGGLKLNAICAKLSRQVVFDHGGAEQARADKGPQRESSNKDLPQPGTKEPGTEFSDGLSHVQKIEEDKRREVIEKWVNGEYEEPLLGRAEGKECRGAEGAEVPPEGVYMVQPKGCSDEEDNGDEADALRGSQDGTFLDDRDSDGAASKDDAYRASSEAASKLGTTSGEASSLRDYAATTMNEFLGMFGYDDQNMRDELARKISFDKLNAATSEATAAAASLPGEDAMSKRARFSKYEEYIRKLKAGEQLSWPMHLAKSEELGSKLGKEASSVLAQPIRLPGPDASMLTETKATILPLPSPSSSQMQGLMSRASKYDFFIQKLKTGESIRPQNGNTYKKASKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVRNIQKLTQVKAPTPSLAPTPLASTPSSAPMAGPEQAVSLPFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPTVSEDVNIYQKYIARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTVECQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGVLGLPASLLGPKDNEQEESSNDDLIDFSAMSSKNSSLSASPTSQQSSVSLIVPAAPSSAAELASSQVSKPANSMTPATKISGLLSQALPSNIPLALALSNSALPGAAGSFFPIIPSRVSTPLPASSANLMTAGSSGANPTSSAPTDSSSQAVSGSGEPSATSSPAPVASIMERISASKGLISPMMARLAAAALKPSVALEAGNGQAAAPGRFNPVQVKQEPAEAMGSSSAAGQESLQEHSLDLSVKDHGNESNGHTVSANSSLLSSLMNKMSKTSASLGNLLNIKTEGDGSQAGAGEPTQYLGKAVKALVQEKLSEPWKMYLRRFGTKDFCDAQCDFLHKVHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAVKSNSESPFSTATDSKASLGPSSPSATSATMASAPALDVPTPSPATVPSAPTLLAWKQLASTIPQMPQIPASVPNLATSPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRPGCYFVTNITTKLPWHVKKT", "length": 1374, "header": "tr|A0A8V0ZKQ6-1|A0A8V0ZKQ6_CHICK Computationally mapped isoform of Castor zinc finger 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZJ27-1" }, "locus": { "chromosome": "21", "start_pos": 3971545, "end_pos": 3833843, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052475.1", "url": "https://www.ensembl.org/id/ENSGALT00010052475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031382.1", "url": "https://www.ensembl.org/id/ENSGALP00010031382.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 515, "start_aa": "Thr", "end_pos": 515, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr515", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 526, "start_aa": "Thr", "end_pos": 526, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr526", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27" } ], "pmid": "" }, { "name": "regulation of neuron differentiation", "id": "GO:0045664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1072, "end_pos": 1074, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZDK9#function" }, { "database": "UniProtKB", "id": "A0A8V0ZDL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDL3#function" }, { "database": "UniProtKB", "id": "A0A8V0ZKW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZRG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3", "locus": { "chromosome": "14", "start_pos": 4540477, "end_pos": 4531979, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021610", "url": "https://www.ensembl.org/id/ENSGALG00010021610" } ] } } ], "crossref": [ { "id": "A0A8V0ZKX3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDK9", "url": "https://www.orthodb.org/?gene=A0A8V0ZDK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDL3", "url": "https://www.orthodb.org/?gene=A0A8V0ZDL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKV4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKW2", "url": "https://www.orthodb.org/?gene=A0A8V0ZKW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKW8", "url": "https://www.orthodb.org/?gene=A0A8V0ZKW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKX3", "url": "https://www.orthodb.org/?gene=A0A8V0ZKX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRG7", "url": "https://www.orthodb.org/?gene=A0A8V0ZRG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15099:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15099:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14972", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14972", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZDK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAWGRRRAGPGSTNSGGGGRESSCSHVGEKSVFKCCSVHSVFPVDRVTLSSTDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTTCLFTPLALPVDYSHYISLPAGVLSMACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV", "length": 218, "header": "tr|A0A8V0ZKX3-1|A0A8V0ZKX3_CHICK Isoform 1 of Transmembrane protein 11 OS=Gallus gallus OX=9031 GN=TMEM11 PE=3 SV=1 CANONICAL=A0A8V0ZKX3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3/entry#A0A8V0ZDK9-1", "sequence": { "sequence": "MSVIFKQPWVTLSSTDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTTCLFTPLALPVDYSHYISLPAGVLSMACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV", "length": 180, "header": "tr|A0A8V0ZDK9-1|A0A8V0ZKX3_CHICK Computationally mapped isoform of Transmembrane protein 11 OS=Gallus gallus OX=9031 GN=TMEM11 PE=3 SV=1 CANONICAL=A0A8V0ZKX3-1" }, "locus": { "chromosome": "14", "start_pos": 4539473, "end_pos": 4535592, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052464.1", "url": "https://www.ensembl.org/id/ENSGALT00010052464.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031371.1", "url": "https://www.ensembl.org/id/ENSGALP00010031371.1" } ] } }, { "isoform_ac": "A0A8V0ZDL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3/entry#A0A8V0ZDL3-1", "sequence": { "sequence": "CHRLGAESSCVLVVRVRESQHSTRVTLSSTDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTTCLFTPLALPVDYSHYISLPAGVLSMACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV", "length": 195, "header": "tr|A0A8V0ZDL3-1|A0A8V0ZKX3_CHICK Computationally mapped isoform of Transmembrane protein 11 OS=Gallus gallus OX=9031 GN=TMEM11 PE=3 SV=1 CANONICAL=A0A8V0ZKX3-1" }, "locus": { "chromosome": "14", "start_pos": 4539473, "end_pos": 4532717, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052471.1", "url": "https://www.ensembl.org/id/ENSGALT00010052471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031378.1", "url": "https://www.ensembl.org/id/ENSGALP00010031378.1" } ] } }, { "isoform_ac": "A0A8V0ZKV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3/entry#A0A8V0ZKV4-1", "sequence": { "sequence": "YKEVCNWSKSAFLNRTKYCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTTCLFTPLALPVDYSHYISLPAGVLSMACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV", "length": 182, "header": "tr|A0A8V0ZKV4-1|A0A8V0ZKV4_CHICK Computationally mapped isoform of Transmembrane protein 11 OS=Gallus gallus OX=9031 GN=TMEM11 PE=3 SV=1 CANONICAL=A0A8V0ZKX3-1" }, "locus": { "chromosome": "14", "start_pos": 4539473, "end_pos": 4534120, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052462.1", "url": "https://www.ensembl.org/id/ENSGALT00010052462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031369.1", "url": "https://www.ensembl.org/id/ENSGALP00010031369.1" } ] } }, { "isoform_ac": "A0A8V0ZKW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3/entry#A0A8V0ZKW2-1", "sequence": { "sequence": "MMALQKSLPYSIFRVTLSSTDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTTCLFTPLALPVDYSHYISLPAGVLSMACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV", "length": 185, "header": "tr|A0A8V0ZKW2-1|A0A8V0ZKW2_CHICK Computationally mapped isoform of Transmembrane protein 11 OS=Gallus gallus OX=9031 GN=TMEM11 PE=3 SV=1 CANONICAL=A0A8V0ZKX3-1" }, "locus": { "chromosome": "14", "start_pos": 4539473, "end_pos": 4537361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052468.1", "url": "https://www.ensembl.org/id/ENSGALT00010052468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031375.1", "url": "https://www.ensembl.org/id/ENSGALP00010031375.1" } ] } }, { "isoform_ac": "A0A8V0ZKW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3/entry#A0A8V0ZKW8-1", "sequence": { "sequence": "ISPRWRRGEGGALVPAAPTAAAVAGRGFLSQDAFLSTEVTLSSTDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTTCLFTPLALPVDYSHYISLPAGVLSMACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV", "length": 209, "header": "tr|A0A8V0ZKW8-1|A0A8V0ZKW8_CHICK Computationally mapped isoform of Transmembrane protein 11 OS=Gallus gallus OX=9031 GN=TMEM11 PE=3 SV=1 CANONICAL=A0A8V0ZKX3-1" }, "locus": { "chromosome": "14", "start_pos": 4539473, "end_pos": 4532014, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052474.1", "url": "https://www.ensembl.org/id/ENSGALT00010052474.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031381.1", "url": "https://www.ensembl.org/id/ENSGALP00010031381.1" } ] } }, { "isoform_ac": "A0A8V0ZKX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3/entry#A0A8V0ZKX3-1", "sequence": { "sequence": "MAAWGRRRAGPGSTNSGGGGRESSCSHVGEKSVFKCCSVHSVFPVDRVTLSSTDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTTCLFTPLALPVDYSHYISLPAGVLSMACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV", "length": 218, "header": "tr|A0A8V0ZKX3-1|A0A8V0ZKX3_CHICK Isoform 1 of Transmembrane protein 11 OS=Gallus gallus OX=9031 GN=TMEM11 PE=3 SV=1 CANONICAL=A0A8V0ZKX3-1" }, "locus": { "chromosome": "14", "start_pos": 4539473, "end_pos": 4532025, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052479.1", "url": "https://www.ensembl.org/id/ENSGALT00010052479.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031386.1", "url": "https://www.ensembl.org/id/ENSGALP00010031386.1" } ] } }, { "isoform_ac": "A0A8V0ZRG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3/entry#A0A8V0ZRG7-1", "sequence": { "sequence": "MSSTSRETAVALCEELIQNCCQALAFPKCSQFLQVRKMVTLSSTDCYIVHEIYNGENAQDQFEYELEQALEAQYKYIVIEPTRIGDETARWITVGNCLHKTAVLAGTTCLFTPLALPVDYSHYISLPAGVLSMACCTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIALAALVYCVKKIYELYAV", "length": 209, "header": "tr|A0A8V0ZRG7-1|A0A8V0ZRG7_CHICK Computationally mapped isoform of Transmembrane protein 11 OS=Gallus gallus OX=9031 GN=TMEM11 PE=3 SV=1 CANONICAL=A0A8V0ZKX3-1" }, "locus": { "chromosome": "14", "start_pos": 4539473, "end_pos": 4538627, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052459.1", "url": "https://www.ensembl.org/id/ENSGALT00010052459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031366.1", "url": "https://www.ensembl.org/id/ENSGALP00010031366.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3" } ], "pmid": "" }, { "name": "inner mitochondrial membrane organization", "id": "GO:0007007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKX3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJ56-1", "uniprot_ac": "A0A8V0ZJ56", "uniprot_id": "A0A8V0ZJ56_CHICK", "mass": { "chemical_mass": 69558.0, "monoisotopic_mass": 69558.0 }, "refseq": { "ac": "XP_417587", "name": "inactive polyglycylase TTLL10 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417587" }, "gene_names": [ { "name": "TTLL10", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ56" } ] }, { "name": "TTLL10", "type": "synonym", "evidence": [ { "id": "XP_417587", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417587" } ] } ], "protein_names": [ { "name": "Tubulin tyrosine ligase like 10", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJ56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ56/entry#names_and_taxonomy" } ] }, { "name": "inactive polyglycylase TTLL10 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_417587", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417587" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417587.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417587", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417587" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ56" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTLL10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ56", "locus": { "chromosome": "21", "start_pos": 2569978, "end_pos": 2589440, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021620", "url": "https://www.ensembl.org/id/ENSGALG00010021620" } ] } } ], "crossref": [ { "id": "A0A8V0ZJ56", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJ56", "database": "AlphaFoldDB", "categories": [] }, { "id": "419426", "url": "https://www.ncbi.nlm.nih.gov/gene/419426", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419426", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419426", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SRMWICK", "url": "https://omabrowser.org/oma/group/SRMWICK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDN1", "url": "https://www.orthodb.org/?gene=A0A8V0ZDN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ56", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46810", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46810", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46810:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46810:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417587", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417587", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEQRGCLSRSWGPTTSPSMPTGNPRSTPEPAPSQDAFVLPKLLTTCPEVKCTSSKLKKGQGAIKALLKYLETAECSPGSAMASVPPKRKRNSRATRQGHHQQQARSLSADRGKPRENLSPTSEAELDRARPCESRMCGKAHPQGKHPEELIREVPMASGPYFYISGSNGAGLVSIYCQSRGWQRIYDNRRQDYALKWCEIKCRETYYHFKEGEQLLYQIPNNSILTSKTGLLSCLREQERVMKKINRSSNPKLLKMEEFFPESFRLDLKEERNAFFEHCKEEEIWICKPSCSNQGRGIFLLKNPSAVTTLQAKLYSSERDLPSKRVPCGAPQTRIVQRYIDQPLLLEGKKFDVRSYLLIACTAPYVLFFAQGYVRLTCSNYDATSDDLTVHLTNQYMQKKNSLYSQLKDETVWGMEHFNSYINEKFGKTNSLPQDWVFTVFTKRMKQIMLQCFLAAKHKLDRKLGYFDLIGCDFLIDENFKVWLLEMNANPALHTNCKVLRDIIPSIIYESLDLVLEIFTKCLKGQSVLPLKTLCHFVLLYNEDAADLGQKQPWKLSTRLCTGRYLRPHTDSTGHIRYSPAKAAGLPPRSSAVPEERVPCCLQRAVGKLS", "length": 611, "header": "tr|A0A8V0ZJ56-1|A0A8V0ZJ56_CHICK Isoform 1 of Tubulin tyrosine ligase like 10 OS=Gallus gallus OX=9031 GN=TTLL10 PE=4 SV=1 CANONICAL=A0A8V0ZJ56-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ56/entry#A0A8V0ZDN1-1", "sequence": { "sequence": "MGVRSNPAKSPRPQYLPLPPLLPPMFSLLSSVPQQSNSKGSPDAHCGRRAKTRPALGLTLPGGLISMRAQLWGAAEPHLHPCWAMELQDTGKVSAAQQRGHGGWSRCPGSAMASVPPKRKRNSRATRQGHHQQQARSLSADRGKPRENLSPTSEAELDRARPCESRMCGKAHPQGKHPEELIREVPMASGPYFYISGSNGAGLVSIYCQSRGWQRIYDNRRQDYALKWCEIKCRETYYHFKEGEQLLYQIPNNSILTSKTGLLSCLREQERVMKKINRSSNPK", "length": 283, "header": "tr|A0A8V0ZDN1-1|A0A8V0ZJ56_CHICK Computationally mapped isoform of Tubulin tyrosine ligase like 10 OS=Gallus gallus OX=9031 GN=TTLL10 PE=4 SV=1 CANONICAL=A0A8V0ZJ56-1" }, "locus": { "chromosome": "21", "start_pos": 2589241, "end_pos": 2577591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052491.1", "url": "https://www.ensembl.org/id/ENSGALT00010052491.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031398.1", "url": "https://www.ensembl.org/id/ENSGALP00010031398.1" } ] } }, { "isoform_ac": "A0A8V0ZJ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ56/entry#A0A8V0ZJ56-1", "sequence": { "sequence": "MAEQRGCLSRSWGPTTSPSMPTGNPRSTPEPAPSQDAFVLPKLLTTCPEVKCTSSKLKKGQGAIKALLKYLETAECSPGSAMASVPPKRKRNSRATRQGHHQQQARSLSADRGKPRENLSPTSEAELDRARPCESRMCGKAHPQGKHPEELIREVPMASGPYFYISGSNGAGLVSIYCQSRGWQRIYDNRRQDYALKWCEIKCRETYYHFKEGEQLLYQIPNNSILTSKTGLLSCLREQERVMKKINRSSNPKLLKMEEFFPESFRLDLKEERNAFFEHCKEEEIWICKPSCSNQGRGIFLLKNPSAVTTLQAKLYSSERDLPSKRVPCGAPQTRIVQRYIDQPLLLEGKKFDVRSYLLIACTAPYVLFFAQGYVRLTCSNYDATSDDLTVHLTNQYMQKKNSLYSQLKDETVWGMEHFNSYINEKFGKTNSLPQDWVFTVFTKRMKQIMLQCFLAAKHKLDRKLGYFDLIGCDFLIDENFKVWLLEMNANPALHTNCKVLRDIIPSIIYESLDLVLEIFTKCLKGQSVLPLKTLCHFVLLYNEDAADLGQKQPWKLSTRLCTGRYLRPHTDSTGHIRYSPAKAAGLPPRSSAVPEERVPCCLQRAVGKLS", "length": 611, "header": "tr|A0A8V0ZJ56-1|A0A8V0ZJ56_CHICK Isoform 1 of Tubulin tyrosine ligase like 10 OS=Gallus gallus OX=9031 GN=TTLL10 PE=4 SV=1 CANONICAL=A0A8V0ZJ56-1" }, "locus": { "chromosome": "21", "start_pos": 2580421, "end_pos": 2570097, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052488.1", "url": "https://www.ensembl.org/id/ENSGALT00010052488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031395.1", "url": "https://www.ensembl.org/id/ENSGALP00010031395.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 15, "start_aa": "Thr", "end_pos": 15, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr15", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419426", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419426", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-glycine ligase activity, elongating", "id": "GO:0070737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 15 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 247, "end_pos": 249 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKT1-1", "uniprot_ac": "A0A8V0ZKT1", "uniprot_id": "A0A8V0ZKT1_CHICK", "mass": { "chemical_mass": 152433.0, "monoisotopic_mass": 152433.0 }, "refseq": {}, "gene_names": [ { "name": "FHOD1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ] } ], "protein_names": [ { "name": "Formin homology 2 domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FHOD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1", "locus": { "chromosome": "11", "start_pos": 1380933, "end_pos": 1365771, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021619", "url": "https://www.ensembl.org/id/ENSGALG00010021619" } ] } } ], "crossref": [ { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056771", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056771", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDN6", "url": "https://www.orthodb.org/?gene=A0A8V0ZDN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKT1", "url": "https://www.orthodb.org/?gene=A0A8V0ZKT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKY4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45920", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45920", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45920:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45920:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZDN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSLHHLPSLLSPRCPSIIYFPFITSCPLHPPAVSSITCCPSVPLQSPPEGPSLHTPCMRGTQSIPVHLEPLGALGASLRPLAPRSPPSTPSPPPAPLYPLEPPEQSPAYTRGGRPSAGRCRLRAGAVPGAVPMPPPELRARCGGGGGAAMAEAAVPCRVQYLEDSDPFGCGSFPEPRRAPVYAVEEALALGAQLPAVHRLLGAPLPLEDCTLQVSPSGHYLDLELSLLEQKDDLEAFYEEVRKGRRPTLILRTQLSVRVHAIIEKLYNSQGPELRRSLFSLKQLFQEDKDLVPEFVNLDGLTCLINVGAEADQNYQNYILRALSQIMLFVDGMQGVINHNETVQWLYTLSGSPFRLVVKMALKLLLVFVEYTEPNALLLIRAVNAVDQARGACPWSNLMAILEQRNGADTELLVFAMTLINKTLAALPDQDSFYDVTDCLEQQGMERVVQQYLSSKGTDLDLKQQFVLYESALRLEDGVEEPPAGGRKERRKTDEGRRGWRAQGSCAEPDPLQSPGSPASPNETPSTPKEPPIEDSPELSIPVEPCPKSILSSASSLRLSLSSPPAEKEPPSVGERSVYKARFLENLAAAQKEKMSAMAKGRIDILSDVTPLEHPVTWDGDGSNPDAGTEPPRMRSHAGRQDVFDSCSTISDTKFMLDMLYAKGSSEPGRQKVFPEEPSLSSRQGEVETDAGSSCAEGPGGQEQESARPHGRAPDGLVASAHAKLARAASSIDAESHTQKLENTVMMPVKNDVELSWERLEAGPVQLKIKDLDFTDLGEEEDLDVLDSGPIANGSFLPGSIEAASAGVLMAPPPLPMVPGCPPPPPPPPVVPGCPPPPPPPPMVPGCPPPPGFSGPSTMDGPSQAKKKRTVKLFWKELKQLDGTVGSGRFGQATLWASLQNVEVNTAKLEHLFESRAKEMPASKKVTDGKKVVVVLDPKRSNAINIGLTVLPPVHIIKTAVLNFDEFAVSKEGIEKILTMVPTEEEKQKIQEAQLANPDVPLGSAEQFLLSLSSISDLTARLQLWAFKLDYESLEQEIAEPLFDLKVGMEQLARNHTFKCILATLLAMGNFLNGSQSRGFELGYLEKVSEVKDTVHRQSLLHHLCQMVVEKFPETTDLYSEIASITRSAKVDFDELANSLVQLERRCRASWDNLKVIAKHEAKPVLKSKLTDFLKDSTQRIVVLKVVHRRVLNRFHSFLLYLGYPASAARDVKVMPICKLLREFALEYRTCRERVLQQQKKRAAHRERNKTRGRLITETEKFSGITEASPPAVVSASPTQQEQAEVGHESMKSVLSSPTDVPARRSRGGRGTGLTTPSQGSPAQEDVPSSPDDASDEIMDRLVKSVTHSANPRPCPSRERRRSRGNRKSLRRTLKSGLSDELVQALGLGRAPGMEV", "length": 1397, "header": "tr|A0A8V0ZKT1-1|A0A8V0ZKT1_CHICK Isoform 1 of Formin homology 2 domain containing 1 OS=Gallus gallus OX=9031 GN=FHOD1 PE=1 SV=1 CANONICAL=A0A8V0ZKT1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1/entry#A0A8V0ZDN6-1", "sequence": { "sequence": 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"length": 1290, "header": "tr|A0A8V0ZDN6-1|A0A8V0ZKT1_CHICK Computationally mapped isoform of Formin homology 2 domain containing 1 OS=Gallus gallus OX=9031 GN=FHOD1 PE=1 SV=1 CANONICAL=A0A8V0ZKT1-1" }, "locus": { "chromosome": "11", "start_pos": 1380668, "end_pos": 1366369, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052496.1", "url": "https://www.ensembl.org/id/ENSGALT00010052496.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031403.1", "url": "https://www.ensembl.org/id/ENSGALP00010031403.1" } ] } }, { "isoform_ac": "A0A8V0ZKT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1/entry#A0A8V0ZKT1-1", "sequence": { "sequence": 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"length": 1397, "header": "tr|A0A8V0ZKT1-1|A0A8V0ZKT1_CHICK Isoform 1 of Formin homology 2 domain containing 1 OS=Gallus gallus OX=9031 GN=FHOD1 PE=1 SV=1 CANONICAL=A0A8V0ZKT1-1" }, "locus": { "chromosome": "11", "start_pos": 1380668, "end_pos": 1365970, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052500.1", "url": "https://www.ensembl.org/id/ENSGALT00010052500.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031407.1", "url": "https://www.ensembl.org/id/ENSGALP00010031407.1" } ] } }, { "isoform_ac": "A0A8V0ZKY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1/entry#A0A8V0ZKY4-1", "sequence": { "sequence": "MTWRLSTRRSEKLYNSQGPELRRSLFSLKQLFQEDKDLVPEFVNLDGLTCLINVGAEADQNYQNYILRALSQIMLFVDGMQGVINHNETVQWLYTLSGSPFRLVVKMALKLLLVFVEYTEPNALLLIRAVNAVDQARGACPWSNLMAILEQRNGADTELLVFAMTLINKTLAALPDQDSFYDVTDCLEQQGMERVVQQYLSSKGTDLDLKQQFVLYESALRLEDGVEEPPAGGRKERRKTDEGRRGWRAQGSCAEPDPLQSPGSPASPNETPSTPKEPPIEDSPELSIPVEPCPKSILSSASSLRLSLSSPPAEKEPPSVGERSVYKARFLENLAAAQKEKMSAMAKGRIDILSDVTPLEHPVTWDGDGSNPDAGTEPPRMRSHAGRQDVFDSCSTISDTKFMLDMLYAKGSSEPGRQKVFPEEPSLSSRQGEVETDAGSSCAEGPGGQEQESARPHGRAPDGLVASAHAKLARAASSIDAESHTQKLENTVMMPVKNDVELSWERLEAGPVQLKIKDLDFTDLGEEEDLDVLDSGPIANGSFLPGSIEAASAGVLMAPPPLPMVPGCPPPPPPPPVVPGCPPPPPPPPMVPGCPPPPGFSGPSTMDGPSQAKKKRTVKLFWKELKQLDGTVGSGRFGQATLWASLQNVEVNTAKLEHLFESRAKEMPASKKVTDGKKVVVVLDPKRSNAINIGLTVLPPVHIIKTAVLNFDEFAVSKEGIEKILTMVPTEEEKQKIQEAQLANPDVPLGSAEQFLLSLSSISDLTARLQLWAFKLDYESLEQEIAEPLFDLKVGMEQLARNHTFKCILATLLAMGNFLNGSQSRGFELGYLEKVSEVKDTVHRQSLLHHLCQMVVEKFPETTDLYSEIASITRSAKVDFDELANSLVQLERRCRASWDNLKVIAKHEAKPVLKSKLTDFLKDSTQRIVVLKVVHRRVLNRFHSFLLYLGYPASAARDVKVMPICKLLREFALEYRTCRERVLQQQKKRAAHRERNKTRGRLITETEKFSGITEASPPAVVSASPTQQEQAEVGHESMKSVLSSPTDVPARRSRGGRGTGLTTPSQGSPAQEDVPSSPDDASDEIMDRLVKSVTHSANPRPCPSRERRRSRGNRKSLRRTLKSGLSDELVQALGLGRAPGMEV", "length": 1143, "header": "tr|A0A8V0ZKY4-1|A0A8V0ZKY4_CHICK Computationally mapped isoform of Formin homology 2 domain containing 1 OS=Gallus gallus OX=9031 GN=FHOD1 PE=1 SV=1 CANONICAL=A0A8V0ZKT1-1" }, "locus": { "chromosome": "11", "start_pos": 1380668, "end_pos": 1371773, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052489.1", "url": "https://www.ensembl.org/id/ENSGALT00010052489.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031396.1", "url": "https://www.ensembl.org/id/ENSGALP00010031396.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 90, "start_aa": "Thr", "end_pos": 90, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr90", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ], "pmid": "" }, { "name": "intercalated disc", "id": "GO:0014704", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014704", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT1" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", 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This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046759238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759238" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMCO4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ7", "locus": { "chromosome": "21", "start_pos": 4777178, "end_pos": 4817183, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020666", "url": "https://www.ensembl.org/id/ENSGALG00010020666" } ] } } ], "crossref": [ { "id": "A0A8V0ZLJ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLJ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "419476", "url": "https://www.ncbi.nlm.nih.gov/gene/419476", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE38", "url": "https://www.orthodb.org/?gene=A0A8V0ZE38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFH1", "url": "https://www.orthodb.org/?gene=A0A8V0ZFH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLJ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZLJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17920", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17920", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17920:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17920:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046759238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759238", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATEERWKSSASKQHSGAEQAGEKESCVLLSQQLGEPERFTYAALCGVSLAWLFPEKEQSSFRTEFIEGLVKWLDLPDAVLPAMTAFASGLGGEGTETFAQLLLKDPTVKDSPAVITQDLLSFSLRDGYYDARVRVLICHICWLLRIPLEELEALEESLLESLKEQTEEESETAEVSRKKKERRRKLKRYLLIGLATVGGGTVIGLTGGLAAPLVAAGAATIIGSAGAAALGSTAGIAVMASLFGAAGAGLTGYKMKKRVGAIEEFEFLPLTEGRQLHITIAITGWLCAGKYGSFTAPWSSMLHSSEQYCLAWESKYLMELGSALDTLVNGFVNMMAQEALKFTVLSGIVTALTWPTSLLTVANVIDNPWGVCLHRSAEVGKHLAHILLSRQQGKRPVTLIGFSLGARVIYFCLQEMAQEKDSQGIIEDVVLLGAPVEGEAKYWKAITKVVSGRIINGYCRGDWLLGFVYRTSSVQLNVAGLQPIKLDDRRMVNMDLSSVVSGHLDYMKQMDTILKAVGIKTKECRQEEKGSTNLFSPLAKKSQRAAGSETWEEDNSVQEEDGADSDCQAPTTSTSVSSALTQPVSAGTSSDGNLHSGDDSLASCAHRQDSPGFLLAESSPPCPACPSSASSAKQAAGDSTD", "length": 642, "header": "tr|A0A8V0ZLJ7-1|A0A8V0ZLJ7_CHICK Isoform 1 of Transmembrane and coiled-coil domains 4 OS=Gallus gallus OX=9031 GN=TMCO4 PE=3 SV=1 CANONICAL=A0A8V0ZLJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZE38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ7/entry#A0A8V0ZE38-1", "sequence": { "sequence": "MRYTSEALTNLPCYRPASMAVKKQRQFVSSISDFHLFCYFFPSAFSSLNLQVKMATEERWKSSASKQHSGAEQAGEKESCVLLSQQLGEPERFTYAALCGVSLAWLFPEKEQSSFRTEFIEGLVKWLDLPDAVLPAMTAFASGLGGEGTETFAQLLLKDPTVKDSPAVITQDLLSFSLRDGYYDARVRVLICHICWLLRIPLEELEALEESLLESLKEQTEEESETAEVSRKKKERRRKLKRYLLIGLATVGGGTVIGLTGGLAAPLVAAGAATIIGSAGAAALGSTAGIAVMASLFGAAGAGLTGYKMKKRVGAIEEFEFLPLTEGRQLHITIAITGWLCAGKYGSFTAPWSSMLHSSEQYCLAWESKYLMELGSALDTLVNGFVNMMAQEALKFTVLSGIVTALTWPTSLLTVANVIDNPWGVCLHRSAEVGKHLAHILLSRQQGKRPVTLIGFSLGARVIYFCLQEMAQEKDSQGIIEDVVLLGAPVEGEAKYWKAITKVVSGRIINGYCRGDWLLGFVYRTSSVQLNVAGLQPIKLDDRRMVNMDLSSVVSGHLDYMKQMDTILKAVGIKTKECRQEEKGSTNLFSPLAKKSQRAAGSETWEEDNSVQEEDGADSDCQAPTTSTSVSSALTQPVSAGTSSDGNLHSGDDSLASCAHRQDSPGFLLAESSPPCPACPSSASSAKQAAGDSTD", "length": 695, "header": "tr|A0A8V0ZE38-1|A0A8V0ZLJ7_CHICK Computationally mapped isoform of Transmembrane and coiled-coil domains 4 OS=Gallus gallus OX=9031 GN=TMCO4 PE=3 SV=1 CANONICAL=A0A8V0ZLJ7-1" }, "locus": { "chromosome": "21", "start_pos": 4814483, "end_pos": 4779822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049918.1", "url": "https://www.ensembl.org/id/ENSGALT00010049918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029479.1", "url": "https://www.ensembl.org/id/ENSGALP00010029479.1" } ] } }, { "isoform_ac": "A0A8V0ZFH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ7/entry#A0A8V0ZFH1-1", "sequence": { "sequence": "MATEERWKSSASKQHSGAEQAGEKESCVLLSQQLGEPERFTYAALCGVSLAWLFPEKEQSSFRTEFIEGLVKWLDLPDAVLPAMTAFASGLGGEGTETFAQLLLKDPTVKDSPAVITQDLLSFSLRDGYYDARVRVLICHICWLLRIPLEELEALEESLLESLKEQTEEESETAEVSRKKKERRRKLKRYLLIGLATVGGGTVIGLTGGLAAPLVAAGAATIIGSAGAAALGSTAGIAVMASLFGAAGAGLTGYKMKKRVGAIEEFEFLPLTEGRQLHITIAITGWLCAGKYGIVTALTWPTSLLTVANVIDNPWGVCLHRSAEVGKHLAHILLSRQQGKRPVTLIGFSLGARVIYFCLQEMAQEKDSQGIIEDVVLLGAPVEGEAKYWKAITKVVSGRIINGYCRGDWLLGFVYRTSSVQLNVAGLQPIKLDDRRMVNMDLSSVVSGHLDYMKQMDTILKAVGIKTKECRQEEKGSTNLFSPLAKKSQRAAGSETWEEDNSVQEEDGADSDCQAPTTSTSVSSALTQPVSAGTSSDGNLHSGDDSLASCAHRQDSPGFLLAESSPPCPACPSSASSAKQAAGDSTD", "length": 587, "header": "tr|A0A8V0ZFH1-1|A0A8V0ZLJ7_CHICK Computationally mapped isoform of Transmembrane and coiled-coil domains 4 OS=Gallus gallus OX=9031 GN=TMCO4 PE=3 SV=1 CANONICAL=A0A8V0ZLJ7-1" }, "locus": { "chromosome": "21", "start_pos": 4814324, "end_pos": 4779822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049924.1", "url": "https://www.ensembl.org/id/ENSGALT00010049924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029485.1", "url": "https://www.ensembl.org/id/ENSGALP00010029485.1" } ] } }, { "isoform_ac": "A0A8V0ZLJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ7/entry#A0A8V0ZLJ7-1", "sequence": { "sequence": "MATEERWKSSASKQHSGAEQAGEKESCVLLSQQLGEPERFTYAALCGVSLAWLFPEKEQSSFRTEFIEGLVKWLDLPDAVLPAMTAFASGLGGEGTETFAQLLLKDPTVKDSPAVITQDLLSFSLRDGYYDARVRVLICHICWLLRIPLEELEALEESLLESLKEQTEEESETAEVSRKKKERRRKLKRYLLIGLATVGGGTVIGLTGGLAAPLVAAGAATIIGSAGAAALGSTAGIAVMASLFGAAGAGLTGYKMKKRVGAIEEFEFLPLTEGRQLHITIAITGWLCAGKYGSFTAPWSSMLHSSEQYCLAWESKYLMELGSALDTLVNGFVNMMAQEALKFTVLSGIVTALTWPTSLLTVANVIDNPWGVCLHRSAEVGKHLAHILLSRQQGKRPVTLIGFSLGARVIYFCLQEMAQEKDSQGIIEDVVLLGAPVEGEAKYWKAITKVVSGRIINGYCRGDWLLGFVYRTSSVQLNVAGLQPIKLDDRRMVNMDLSSVVSGHLDYMKQMDTILKAVGIKTKECRQEEKGSTNLFSPLAKKSQRAAGSETWEEDNSVQEEDGADSDCQAPTTSTSVSSALTQPVSAGTSSDGNLHSGDDSLASCAHRQDSPGFLLAESSPPCPACPSSASSAKQAAGDSTD", "length": 642, "header": "tr|A0A8V0ZLJ7-1|A0A8V0ZLJ7_CHICK Isoform 1 of Transmembrane and coiled-coil domains 4 OS=Gallus gallus OX=9031 GN=TMCO4 PE=3 SV=1 CANONICAL=A0A8V0ZLJ7-1" }, "locus": { "chromosome": "21", "start_pos": 4814324, "end_pos": 4779822, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049927.1", "url": "https://www.ensembl.org/id/ENSGALT00010049927.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029488.1", "url": "https://www.ensembl.org/id/ENSGALP00010029488.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLM2-1", "uniprot_ac": "A0A8V0ZLM2", "uniprot_id": "A0A8V0ZLM2_CHICK", "mass": { "chemical_mass": 24872.0, "monoisotopic_mass": 24872.0 }, "refseq": {}, "gene_names": [ { "name": "C1orf52", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM2" } ] } ], "protein_names": [ { "name": "C1orf52 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1orf52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM2", "locus": { "chromosome": "8", "start_pos": 16024651, "end_pos": 16022340, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020686", "url": "https://www.ensembl.org/id/ENSGALG00010020686" } ] } } ], "crossref": [ { "id": "A0A8V0ZLM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE72", "url": "https://www.orthodb.org/?gene=A0A8V0ZE72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLM2", "url": "https://www.orthodb.org/?gene=A0A8V0ZLM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31833", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31833", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31833:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31833:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15559", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15559", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZE72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQKGQLFPSPSPERRLPPAKQAGAGGRNPRRGAGFRAGGELRSPAMAAEGEDPLGYFAAYGSSSSDSEADEASAEERQGGAGAAAGSSPGRRPKLPPPDELFRKVSQPPAFLYNPLNKQIDWESRVLRAPEEPPKEFKAWKTNAVPPPEVYSPPEKKPPPAPAVDMAIKWSNIYEDNGDDAPRPAGRARFLPEEEEEHTVSDDEKDDEPAYAKKRKLDSGEKMKRKKV", "length": 228, "header": "tr|A0A8V0ZLM2-1|A0A8V0ZLM2_CHICK Isoform 1 of C1orf52 homolog OS=Gallus gallus OX=9031 GN=C1orf52 PE=1 SV=1 CANONICAL=A0A8V0ZLM2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZE72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM2/entry#A0A8V0ZE72-1", "sequence": { "sequence": "MAAEGEDPLGYFAAYGSSSSDSEADEASAEERQGGAGAAAGSSPGRRPKLPPPDELFRKVSQPPAFLYNPLNKQIDWESRVLRAPEEPPKEFKAWKTNAVPPPEVYSPPEKKPPPAPAVDMAIKWSNIYEDNGDDAPRPAGRARFLPEEEEEHTVSGRAAGGAAAAAGAPGRVGAHLQGIL", "length": 181, "header": "tr|A0A8V0ZE72-1|A0A8V0ZLM2_CHICK Computationally mapped isoform of C1orf52 homolog OS=Gallus gallus OX=9031 GN=C1orf52 PE=1 SV=1 CANONICAL=A0A8V0ZLM2-1" }, "locus": { "chromosome": "8", "start_pos": 16023351, "end_pos": 16022674, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049968.1", "url": "https://www.ensembl.org/id/ENSGALT00010049968.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029515.1", "url": "https://www.ensembl.org/id/ENSGALP00010029515.1" } ] } }, { "isoform_ac": "A0A8V0ZLM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM2/entry#A0A8V0ZLM2-1", "sequence": { "sequence": "MQKGQLFPSPSPERRLPPAKQAGAGGRNPRRGAGFRAGGELRSPAMAAEGEDPLGYFAAYGSSSSDSEADEASAEERQGGAGAAAGSSPGRRPKLPPPDELFRKVSQPPAFLYNPLNKQIDWESRVLRAPEEPPKEFKAWKTNAVPPPEVYSPPEKKPPPAPAVDMAIKWSNIYEDNGDDAPRPAGRARFLPEEEEEHTVSDDEKDDEPAYAKKRKLDSGEKMKRKKV", "length": 228, "header": "tr|A0A8V0ZLM2-1|A0A8V0ZLM2_CHICK Isoform 1 of C1orf52 homolog OS=Gallus gallus OX=9031 GN=C1orf52 PE=1 SV=1 CANONICAL=A0A8V0ZLM2-1" }, "locus": { "chromosome": "8", "start_pos": 16024040, "end_pos": 16022539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049973.1", "url": "https://www.ensembl.org/id/ENSGALT00010049973.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029519.1", "url": "https://www.ensembl.org/id/ENSGALP00010029519.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLM7-1", "uniprot_ac": "A0A8V0ZLM7", "uniprot_id": "A0A8V0ZLM7_CHICK", "mass": { "chemical_mass": 96821.0, "monoisotopic_mass": 96821.0 }, "refseq": { "ac": "XP_004943023", "name": "cilia- and flagella-associated protein 221 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943023" }, "gene_names": [ { "name": "CFAP221", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ] }, { "name": "CFAP221", "type": "synonym", "evidence": [ { "id": "XP_004943023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943023" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 221", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 221 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943023" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943023.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943023" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP221", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7", "locus": { "chromosome": "7", "start_pos": 27947927, "end_pos": 27986924, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020680", "url": "https://www.ensembl.org/id/ENSGALG00010020680" } ] } } ], "crossref": [ { "id": "A0A8V0ZLM7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "424272", "url": "https://www.ncbi.nlm.nih.gov/gene/424272", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424272", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424272", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TYNPPQW", "url": "https://omabrowser.org/oma/group/TYNPPQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZE76", "url": "https://www.orthodb.org/?gene=A0A8V0ZE76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFC3", "url": "https://www.orthodb.org/?gene=A0A8V0ZFC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFJ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZFJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLM7", "url": "https://www.orthodb.org/?gene=A0A8V0ZLM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46500", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46500", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46500:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46500:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZE76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVVESASTEIFKKIPSVLGSLVEEPKKRHAIPNHLLESKVYSERKKSNVIQAEPAVLHYGGYEVGKHHQQTLKLINISDNVINPHIIPPQTKYFLIKYNKTHRLVPGLSYVVTVDFCPDEWRYYYDCIRIHCQGEDTLVVPVHAYPTVNVLEFPSFINMSDVSIGQSKEYVIPLQCSCPIDFEFHIDFIQPHRAFTVQPISGIIPGNGKEEVTVKYSPLEYGTAQMKMQLLISQFHSKPYVCVFTGTSTPHLGQIKEQFEKQQRHPEKKAASIGKSLVWRRDKFSLPRSKAIQKVKEIEYQNLKFPTDLSNPYAVATVLNQEPGKLKIKNLKEVLCQGNEGIKTRQMKEAMFELKVKQNIKEEEANNLKWQVRKGKDPVSVEFKREVIESREREEEQYKIQRGDPIIEKEFQRNEVEVSSRRVLRLVEQHSNVHPTFDLLRNDPWANRNRMLRKFQQAAYKIVIQSRLNHLLLLFRGLTREAEGLEESSTSEKGSLRQTEGSEEPKGISSSISEDQILPSQFSSYGFLKVRRDLEPDALGPVPVKPIGVKMKRFLPIYSLKVPQHFSIIKYQPLRAHRTAASSKTQKLFRALRQGAQDELAQVVASPKDYHKPSSEEVAERDIGLLKLVPPQALVYPTESNPLRIFNPTPGLFPLLPPLTYCETNIEYHLCPHPKYTFTKECPKGSSIPITQKKFLHHEEVICGVMDWRQFLPVVYLTFPNTPISTSTTSRDPYSLDMLPRDVPPVLYNLPERDRENVIDLGTDETEFEVLLTPEMLSAEFPQIEQMLTEEGKVKSAKKERDPHKHPDGDFQPQDNGLRERVQKHMEKMKMKALNKALILD", "length": 842, "header": "tr|A0A8V0ZLM7-1|A0A8V0ZLM7_CHICK Isoform 1 of Cilia and flagella associated protein 221 OS=Gallus gallus OX=9031 GN=CFAP221 PE=4 SV=1 CANONICAL=A0A8V0ZLM7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZE76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7/entry#A0A8V0ZE76-1", "sequence": { "sequence": "MDVVESASTEIFKKIPSVLGSLVEEPKKRHAIPNHLLESKVYSERKKSNVIQAEPAVLHYGGYEVGKHHQQTLKLINISDNVINPHIIPPQTKYFLIKYNKTHRLVPGLSYVVTVDFCPDEWRYYYDCIRIHCQGEDTLVVPVHAYPTVNVLEFPSFINMSDVSIGQSKEYVIPLQCSCPIDFEFHIDFIQPHRAFTVQPISGIIPGNGKEEVTVKYSPLEYGTAQMKMQLLISQFHSKPYVCVFTGTSTPHLGQIKEQFEKQQRHPEKKAASIGKSLVWRRDKFSLPRSKAIQKVKEIEYQNLKFPTDLSNPYAVATVLNQEPGKLKIKNLKEVLCQGNEGIKTRQMKEAMFELKVKQNIKEEEANNLKWQVRKGKDPVSVEFKREVIESREREEEQYKIQRGDPIIEKEFQRNEVEVSSRRVLRLVEQHSNVHPTFDLLRNDPWANRNRMLRKFQQAAYKIVIQSRLNHLLLLFRGLTREAEGLEESSTSEKGSLRQTEGSEEPKGISSSISEDQILPSQFSSYGFLKVRRDLEPDALGPVPVKPIGVKMKRFLPIYSLKVPQHFSIIKYQPLRAHRTAASSKTQKLFRALRQGAQDELAQVVASPKDYHKPSSEEVAERDIGLLKLVPPQALVYPTESNPLRIFNPTPGLFPLLPPLTYCETNIEYHLCPHPKYTFTKECPKGSSIPITQKKFLHHEEVICGVMDWRQFLPVVYLTFPNTPISTSTTSRDPYSLDMLPRDVPPVLYNLPERDRENVIDLGTDETEFEVLLTPEMLSAEFPQIEQMLTEEGKVKSAKKER", "length": 802, "header": "tr|A0A8V0ZE76-1|A0A8V0ZLM7_CHICK Computationally mapped isoform of Cilia and flagella associated protein 221 OS=Gallus gallus OX=9031 GN=CFAP221 PE=4 SV=1 CANONICAL=A0A8V0ZLM7-1" }, "locus": { "chromosome": "7", "start_pos": 27965984, "end_pos": 27950109, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049975.1", "url": "https://www.ensembl.org/id/ENSGALT00010049975.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029520.1", "url": "https://www.ensembl.org/id/ENSGALP00010029520.1" } ] } }, { "isoform_ac": "A0A8V0ZFC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7/entry#A0A8V0ZFC3-1", "sequence": { "sequence": "MDVVESASTEIFKKIPSVLGSLVEEPKKRHAIPNHLLESKVYSERKKSNVIQAEPAVLHYGGYEVGKHHQQTLKLINISDNVINPHIIPPQTKYFLIKYNKTHRLVPGLSYVVTVDFCPDEWRYYYDCIRIHCQGEDTLVVPVHAYPTVNVLEFPSFINMSDVSIGQSKEYVIPLQCSCPIDFEFHIDFIQPHRAFTVQPISGIIPGNGKEEVTVKYSPLEYGTAQMKMQLLISQFHSKPYVCVFTGTSTPHLGQIKEQFEKQQRHPEKKAASIGKSLVWRRDKFSLPRSKAIQKVKSFAKAMKE", "length": 305, "header": "tr|A0A8V0ZFC3-1|A0A8V0ZLM7_CHICK Computationally mapped isoform of Cilia and flagella associated protein 221 OS=Gallus gallus OX=9031 GN=CFAP221 PE=4 SV=1 CANONICAL=A0A8V0ZLM7-1" }, "locus": { "chromosome": "7", "start_pos": 27965984, "end_pos": 27959974, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049970.1", "url": "https://www.ensembl.org/id/ENSGALT00010049970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029517.1", "url": "https://www.ensembl.org/id/ENSGALP00010029517.1" } ] } }, { "isoform_ac": "A0A8V0ZFJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7/entry#A0A8V0ZFJ2-1", "sequence": { "sequence": "MWLNQPPQKSSRKYPVFWAAWWRNLKRDMLSPITCWNQHRLVPGLSYVVTVDFCPDEWRYYYDCIRIHCQGEDTLVVPVHAYPTVNVLEFPSFINMSDVSIGQSKEYVIPLQCSCPIDFEFHIDFIQPHRAFTVQPISGIIPGNGKEEVTVKYSPLEYGTAQMKMQLLISQFHSKPYVCVFTGTSTPHLGQIKEQFEKQQRHPEKKAASIGKSLVWRRDKFSLPRSKAIQKVKEIEYQNLKFPTDLSNPYAVATVLNQEPGKLKIKNLKEVLCQGNEGIKTRQMKEAMFELKVKQNIKEEEANNLKWQVRKGKDPVSVEFKREVIESREREEEQYKIQRGDPIIEKEFQRNEVEVSSRRVLRLVEQHSNVHPTFDLLRNDPWANRNRMLRKFQQAAYKIVIQSRLNHLLLLFRGLTREAEGLEESSTSEKGSLRQTEGSEEPKGISSSISEDQILPSQFSSYGFLKVRRDLEPDALGPVPVKPIGVKMKRFLPIYSLKVPQHFSIIKYQPLRAHRTAASSKTQKLFRALRQGAQDELAQVVASPKDYHKPSSEEVAERDIGLLKLVPPQALVYPTESNPLRIFNPTPGLFPLLPPLTYCETNIEYHLCPHPKYTFTKECPKGSSIPITQKKFLHHEEVICGVMDWRQFLPVVYLTFPNTPISTSTTSRDPYSLDMLPRDVPPVLYNLPERDRENVIDLGTDETEFEVLLTPEMLSAEFPQIEQMLTEEGKVKSAKKERDPHKHPDGDFQPQDNGLRERVQKHMEKMKMKALNKALILD", "length": 778, "header": "tr|A0A8V0ZFJ2-1|A0A8V0ZLM7_CHICK Computationally mapped isoform of Cilia and flagella associated protein 221 OS=Gallus gallus OX=9031 GN=CFAP221 PE=4 SV=1 CANONICAL=A0A8V0ZLM7-1" }, "locus": { "chromosome": "7", "start_pos": 27965980, "end_pos": 27948252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049963.1", "url": "https://www.ensembl.org/id/ENSGALT00010049963.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029511.1", "url": "https://www.ensembl.org/id/ENSGALP00010029511.1" } ] } }, { "isoform_ac": "A0A8V0ZLM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7/entry#A0A8V0ZLM7-1", "sequence": { "sequence": "MDVVESASTEIFKKIPSVLGSLVEEPKKRHAIPNHLLESKVYSERKKSNVIQAEPAVLHYGGYEVGKHHQQTLKLINISDNVINPHIIPPQTKYFLIKYNKTHRLVPGLSYVVTVDFCPDEWRYYYDCIRIHCQGEDTLVVPVHAYPTVNVLEFPSFINMSDVSIGQSKEYVIPLQCSCPIDFEFHIDFIQPHRAFTVQPISGIIPGNGKEEVTVKYSPLEYGTAQMKMQLLISQFHSKPYVCVFTGTSTPHLGQIKEQFEKQQRHPEKKAASIGKSLVWRRDKFSLPRSKAIQKVKEIEYQNLKFPTDLSNPYAVATVLNQEPGKLKIKNLKEVLCQGNEGIKTRQMKEAMFELKVKQNIKEEEANNLKWQVRKGKDPVSVEFKREVIESREREEEQYKIQRGDPIIEKEFQRNEVEVSSRRVLRLVEQHSNVHPTFDLLRNDPWANRNRMLRKFQQAAYKIVIQSRLNHLLLLFRGLTREAEGLEESSTSEKGSLRQTEGSEEPKGISSSISEDQILPSQFSSYGFLKVRRDLEPDALGPVPVKPIGVKMKRFLPIYSLKVPQHFSIIKYQPLRAHRTAASSKTQKLFRALRQGAQDELAQVVASPKDYHKPSSEEVAERDIGLLKLVPPQALVYPTESNPLRIFNPTPGLFPLLPPLTYCETNIEYHLCPHPKYTFTKECPKGSSIPITQKKFLHHEEVICGVMDWRQFLPVVYLTFPNTPISTSTTSRDPYSLDMLPRDVPPVLYNLPERDRENVIDLGTDETEFEVLLTPEMLSAEFPQIEQMLTEEGKVKSAKKERDPHKHPDGDFQPQDNGLRERVQKHMEKMKMKALNKALILD", "length": 842, "header": "tr|A0A8V0ZLM7-1|A0A8V0ZLM7_CHICK Isoform 1 of Cilia and flagella associated protein 221 OS=Gallus gallus OX=9031 GN=CFAP221 PE=4 SV=1 CANONICAL=A0A8V0ZLM7-1" }, "locus": { "chromosome": "7", "start_pos": 27965984, "end_pos": 27948252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049980.1", "url": "https://www.ensembl.org/id/ENSGALT00010049980.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029524.1", "url": "https://www.ensembl.org/id/ENSGALP00010029524.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424272", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424272", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0U0-1", "protein_name": "Cilia and flagella associated protein 221", "gene_name": "Cfap221", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVKSPMQELKNANEPFDTMSPILLKSLVEEPKKRTEVPNHLLESKVYAKLLNNKVIQARPGIVHFGGYTIEKEHQQILNIANISDEDTHLHILPPQTKYFQISFEKKEHRLIPGLSLTVTITFSPDEWRYYYDCIRIHCKGDDTLLVPIHAYPVLNDLDFPTFINLSDVLLGESKSYVIPLQCSCPVDFEFHITLLRSHQAFTIEPKSGIIPANGEARVTVTFTPIQYGIAQIKIQLWISQFNSQPYECVFTGTCHPNIALPLEEFKRLNDRSKKVNVPLEKTAYVQFYPTVAQAKKPQKLKEIDYQDLRFPADLSNPFAVATVLNQEAGKMKIKDLKQVLDQGDEVSKTKQMKEAIFEQKVRQDIVTEIENHLKWQVHLGKEHTTYKFKKELIEERQKAREKYKQNRGDPIIGEELQRLQMKQSKKRIVHNLEEKVQEFHANFDPLINNMWLSRHRAQRRFQQAARKIMLERRLLLMLCAIREMDKEGIMRKLVQVKRSLVQAENPYRSLKVRVSQDDNLWPYSLQPEEVLHFAFPTDSQSYNELALDGLGLVPIKSSDIQIKHNYPFFTLKVPQLYKIKGYHPFSVNKSSTNYRLQKLARPLKHGAEDEVTTIITLPKKNTVQVSEKPSILSMKPPEGLAMSVEYDPLYIFNPSPGLFTMKHPLTYEETLIDYHLCTHPKYKYTQEPHQGSSIPLTQKQFLHHTDIIPGIMNWKKFQPLVFSSMSESSKENTQRSDWYSPVMLPIDIPSPLEDLPEEDRLETTERDLCDQDIEVMLTPEMIQVEFPILTHRDSKKEKDFKDPTQLPEKVGEKVQEEMKNLRNKALNTYLILD", "length": 836 }, "evidence": [ { "id": "A0A8V0ZLM7", "url": "https://omabrowser.org/oma/group/A0A8V0ZLM7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A480DI89-1", "protein_name": "Cilia and flagella associated protein 221", "gene_name": "CFAP221", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAVKTPSREVKNAEEPFQNMSPLPLRSLVEEPKKRGAVPNHLLESKVYAKLLKNKVLQAKPGILHFGGYQVEKQHQQILHLVNICNEDTHVHILPPQTKYFQIKYVKKENRLVPGLSLTVTVIFSPDEWRYYYDCIRVHCKGDETLLVPIHAYPVANTLDFPSFINLSNVLLGESKSYVIPLQCSCPVDFEFHVTLIQSHPAFTVEPSSGIIPANGKMNATVRFTPFQYGTAQIKLQLWISQFNSQPYECVFTGTCYPNMALKLEEFERLNTLARKVAVPPEKAMIPVRFHRLTTNLKPPKLKEIEYQNLRFPVDLSNPFAVATVLNQEPGKLKIKELREVLDQGTEISKTRQMKEALFEQKVRQDTYEELENHLKWQVHLGKDPMSFKLKKDLMEERQRINQKYKLDRGDPILEEEFQRLKTEVNPKRVVRDLEENIREFHPNFDPVINNTWVNRFRAQRRFQQAARKVIVHRRLLTMLDAVRNMRGEAVIRKFTEGRQSTAQDQNSSKYLRSQVSQDDYPIQFPVSPETVLPFAFPSYSPPQASNELAPDGLGPVPIKSSEIQIKQPYSFFNLQVPQQYKIKGYQPISVQKASNSYRPQKLARALKQGAEDEATTVIALPKEDAVCAPQLPGETSILSLKLPEALARAPDYDPLYIFNPSPGLFAVMHPLTYAETLIDYHLCSHPKYRFTKESHSGSSIPLTQKQFLHHTDIIPGVMTWKKFQSLALSSLPETSKIETSQSCDSFNLVMLPVNVPAVLDALPEEDKMETFERELCEQSVEIMLTPEMIEVEFPMLDYKDTKKEKEMKDQAQPVEKAAEKVLEEMKNLRGKALNSYLILE", "length": 842 }, "evidence": [ { "id": "A0A8V0ZLM7", "url": "https://omabrowser.org/oma/group/A0A8V0ZLM7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A9Q751-1", "protein_name": "Cilia- and flagella-associated protein 221", "gene_name": "Cfap221", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVVKSPMQELQQAKEPFDTMSPLLLKSLVEEPKKRTEVPNHLLESRVYAKLLNNKVIQARPGIVHFGGYEIESKHQQILNIANISDEDTHLHILPPQTKYFQINFEKKEHRLIPGLSLTVTITFSPDEWRYYYDCIRIHCKGDDTLLVPIHAYPVLNNLDFPTFINLSDVFLGESKSYVIPLQCSCPVDFEFHITLLRSHQAFTIEPKSGIIPANGKAKVTVKFTPIQYGMAQIKIQLWISQFNSQPYECVFTGTCYPNMALPLEEFKRLNTRSKKVNVPLEKTTYVQFYPAPAKAKPQKLKEIDYQDLRFPADLSNPFAVATVLNQEPGKLKIKELKQVLDQGDEISKTRQMKEAIFEQKVRQDILTEIENHLKWQVHLGKEHTTYRFKRELTEEWKKARAKYKQNRGDPVEGEELQRLQTEQSQKRIVRDLKGKRQEFHPNFDPLVNNVWLTRHRAQRRFQQAARKIMLERRLLSMLGAIRGMDKESILRKIIQVNGKLIQGENPSRGRRAHLKQEDNIWRYSLESEEVLHFAFPTDSESYNELALDGLGLVPIKSPEIQIKHSYPYFTLKVPQLYKIKGYHPFSVNKSSTNYRLQKLARPLKHGAEDEVTTIITIPKKDTTPLSAKPSILSMKPPEGLAMSVEYDPLYIFNPSPGLFAVKHPLTYAETLIDYHLCSHPKYKYTQESHMGSSIPLTQRQFLHHTDIIPGIMNWKKFQPLVFSSMSDPSMVEATQRSDWYSSVMLPIDVPAPLEDLPEEDRLETTERDLCDQGIEVMLTPEMVQVEFPMLIHRDSKKEKDFKDSTQLPEKVGERVQEEMKNLRSKALNTYLILD", "length": 836 }, "evidence": [ { "id": "A0A8V0ZLM7", "url": "https://omabrowser.org/oma/group/A0A8V0ZLM7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4G0U5-1", "protein_name": "Cilia- and flagella-associated protein 221", "gene_name": "CFAP221", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVVKTPSRGLKNAKEPFNNASPHLLKNLVEEPKKRKEVPNHLLESKVYAKLVNNKVIQARPGIIHFGGYQVEKQHQQILHLVNVSNEDTRVHILPPQTKYFEINYVRKEHHLVPGLSLTVTVTFSPDEWRYYYDCIRVHCKGDDTLLVPIHAYPVMNSLDFPSFINLSNVLLGESKTYVIPLQCSCPVDFEFYITLIQSHQAFAIEPTSGIIPANGKMTVTIKFTPFQYGTAQIKMQLWISQFNSQPYECVFTGTCYPNMALPLEEFERLNTLSKKVNVPPEKAMMHINFHRPPAKPKPQKVKEIEYQNLRFPVDLSNPFAVATVLNQEPGKLKIKELREVLDQGTEISKTRQMKEALFEQKVRQDIHEEMENHLKWQVHLGKDPMSFKLKKELTEEWQKACAKYKLDRGDPILDEEFQRLKTEVSHKRVVRNQEEKIKEFHPTFDPLINNTWLSRSRAQKRFQQVARKVMIQGRLFNMLSAVREMDKESILRKIGQAKQSIAQEANFFKFFLRRISQDDYTSRFSVSPKEVLPFAFPDCSPPQDSNELAPDGLGLVPIKSSEVQIKQSYSFFNLQVPQLYKIKRYQPFSVHKSSTSYRPQKLARALKQGAEDEVTTITALPKQDSTTQLSGKTSVLSMKPPEALAMSLDYDPLYVFNPNPGLFAVMHPLTYAETLIDYHLCSHPKYKFTKESRHGSSIPVTQKQFLHHTDIIPGIMHWKSFQSLVLSSLPDPSKMETTKSCDSFNSFMLPIDVPAILDALPEEDRLETVERELCEQNVEVMLTPEMIKVEFPMLNYKDIRKEKEVKDQAQPAEKAGEKLLEEMRNLRGKALNTYLILE", "length": 840 }, "evidence": [ { "id": "A0A8V0ZLM7", "url": "https://omabrowser.org/oma/group/A0A8V0ZLM7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" }, { "name": "manchette", "id": "GO:0002177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" }, { "name": "ciliary tip", "id": "GO:0097542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097542", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" }, { "name": "9+2 motile cilium", "id": "GO:0097729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" }, { "name": "sperm head-tail coupling apparatus", "id": "GO:0120212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120212", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" }, { "name": "cilium movement", "id": "GO:0003341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003341", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" }, { "name": "motile cilium assembly", "id": "GO:0044458", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044458", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM7" }, { "id": "PF22067", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cep192-like", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 241, "start_aa": "Asp", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLS8-1", "uniprot_ac": "A0A8V0ZLS8", "uniprot_id": "A0A8V0ZLS8_CHICK", "mass": { "chemical_mass": 31641.0, "monoisotopic_mass": 31641.0 }, "refseq": {}, "gene_names": [ { "name": "MMAB", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8" } ] } ], "protein_names": [ { "name": "Metabolism of cobalamin associated B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion. Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP-binding to MMAB and gated by MMAA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF2#function" }, { "database": "UniProtKB", "id": "ARBA00056747", "url": "https://www.uniprot.org/uniprotkb/ARBA00056747#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MMAB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8", "locus": { "chromosome": "15", "start_pos": 6784125, "end_pos": 6788411, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021715", "url": "https://www.ensembl.org/id/ENSGALG00010021715" } ] } } ], "crossref": [ { "id": "A0A8V0ZLS8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLS8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100859013", "url": "https://www.ncbi.nlm.nih.gov/gene/100859013", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HQACTVV", "url": "https://omabrowser.org/oma/group/HQACTVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEF2", "url": "https://www.orthodb.org/?gene=A0A8V0ZEF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJW7", "url": "https://www.orthodb.org/?gene=A0A8V0ZJW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLS8", "url": "https://www.orthodb.org/?gene=A0A8V0ZLS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12213:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12213:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9759218", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9759218", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "56796", "url": "https://www.rhea-db.org/rhea/56796", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZEF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRRAAAAAAGSGLGRPLWVVAGRGQSGEAGSPEGGPPSARSPRIYTRTGDEGFSSTFTGERRPKGDRIFEALGTTDELSSAIGLASELSSEKGHAFVEQLHKVQCMLQDVGSNIATPLSSAREAHLKRTSFSEEPILELEKWIDRYSEQLPPLRAFILPCGSLSTSRGGRSKRGQIFKQTERLPLRFGTLCCNEGREGRENIYKAKTITGSWDVYAVDLGKLNPAERFSRHGWQREQAQIGNVSCQRLPVNMMGTLFINAVRNTAVLSTRPCSDTVVLVSELLFALDQS", "length": 290, "header": "tr|A0A8V0ZLS8-1|A0A8V0ZLS8_CHICK Isoform 1 of Metabolism of cobalamin associated B OS=Gallus gallus OX=9031 GN=MMAB PE=1 SV=1 CANONICAL=A0A8V0ZLS8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8/entry#A0A8V0ZEF2-1", "sequence": { "sequence": "MLRRAAAAAAGSGLGRPLWVVAGRGQSGEAGSPEGGPPSARSPRIYTRTGDEGFSSTFTGERRPKGDRIFEALGTTDELSSAIGLASELSSEKGHAFVEQLHKVQCMLQDVGSNIATPLSSAREAHLKRTSFSEEPILELEKWIDRYSEQLPPLRAFILPSGGKSSAALHFSRAVCRRAERCVVPLVQAGEADPNVAKYLNRLSDYLFVLARYAAMKEGKEEKIYTKPKP", "length": 230, "header": "tr|A0A8V0ZEF2-1|A0A8V0ZLS8_CHICK Computationally mapped isoform of Metabolism of cobalamin associated B OS=Gallus gallus OX=9031 GN=MMAB PE=1 SV=1 CANONICAL=A0A8V0ZLS8-1" }, "locus": { "chromosome": "15", "start_pos": 6787928, "end_pos": 6784601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052768.1", "url": "https://www.ensembl.org/id/ENSGALT00010052768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031674.1", "url": "https://www.ensembl.org/id/ENSGALP00010031674.1" } ] } }, { "isoform_ac": "A0A8V0ZJW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8/entry#A0A8V0ZJW7-1", "sequence": { "sequence": "GRDGAVSGAVPPRRALEPRRRLPCRAPRRARRAGSPSPGRTPAGRAPTSPPPPERERRGLRSPEGGPPSARSPRIYTRTGDEGFSSTFTGERRPKGDRIFEALGTTDELSSAIGLASELSSEKGHAFVEQLHKVQCMLQDVGSNIATPLSSAREAHLKRTSFSEEPILELEKWIDRYSEQLPPLRAFILPSGGKSSAALHFSRAVCRRAERCVVPLVQAGEADPNVAKYLNRLSDYLFVLARYAAMKEGKEEKIYTKPKP", "length": 260, "header": "tr|A0A8V0ZJW7-1|A0A8V0ZJW7_CHICK Computationally mapped isoform of Corrinoid adenosyltransferase MMAB OS=Gallus gallus OX=9031 GN=MMAB PE=1 SV=1 CANONICAL=A0A8V0ZLS8-1" }, "locus": { "chromosome": "15", "start_pos": 6788355, "end_pos": 6784601, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052776.1", "url": "https://www.ensembl.org/id/ENSGALT00010052776.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031681.1", "url": "https://www.ensembl.org/id/ENSGALP00010031681.1" } ] } }, { "isoform_ac": "A0A8V0ZLS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8/entry#A0A8V0ZLS8-1", "sequence": { "sequence": "MLRRAAAAAAGSGLGRPLWVVAGRGQSGEAGSPEGGPPSARSPRIYTRTGDEGFSSTFTGERRPKGDRIFEALGTTDELSSAIGLASELSSEKGHAFVEQLHKVQCMLQDVGSNIATPLSSAREAHLKRTSFSEEPILELEKWIDRYSEQLPPLRAFILPCGSLSTSRGGRSKRGQIFKQTERLPLRFGTLCCNEGREGRENIYKAKTITGSWDVYAVDLGKLNPAERFSRHGWQREQAQIGNVSCQRLPVNMMGTLFINAVRNTAVLSTRPCSDTVVLVSELLFALDQS", "length": 290, "header": "tr|A0A8V0ZLS8-1|A0A8V0ZLS8_CHICK Isoform 1 of Metabolism of cobalamin associated B OS=Gallus gallus OX=9031 GN=MMAB PE=1 SV=1 CANONICAL=A0A8V0ZLS8-1" }, "locus": { "chromosome": "15", "start_pos": 6787928, "end_pos": 6784356, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052771.1", "url": "https://www.ensembl.org/id/ENSGALT00010052771.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031677.1", "url": "https://www.ensembl.org/id/ENSGALP00010031677.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9759218", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9759218", "resource": "Reactome", "description": "Cobalamin (Cbl) metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FZ58-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "Mmab", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVWVFGGRLGLRRHLDVCRLLCPRFQSRGPQSEEDGNRPKSSSKAHKIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFAMELITEKGHTFAKELQKIQCTLQDVGSALATPRSSAREAHLKYTTFKEGPIVELEQWIDKYSSQLPPLTAFILPSGGKSSSALHFCRAVCRRAERRLEADSPAHEGTKTTLVGTKASLPSAYLLCLLLHWPGHVMSVQVWCLLSKWEKRMQMWPSF", "length": 249 }, "evidence": [ { "id": "A0A8V0ZLS8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLS8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0L5G5-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "Mmab", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVWTFGGRLGLRGRLGGCRLLCPRFQSFGPQGGEDGDRPQPSSKAAKVLKIYTKTGDKGLSSTFTGERRPKDDQVFEALGTTDELSSAIGFAMELITEKGHTFAEELRKIQCTLQDVGSALATPRSSAREAHLKHTAFQEEPILELEQWIDKYSSQLPPLTAFILPSGGKSSSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNSSGRAEPGAGATCRLLGWRSSPGLSDYLFTVARYAAMKEGSQEKIYKKRDV", "length": 259 }, "evidence": [ { "id": "A0A8V0ZLS8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLS8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2BGN0-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "mmab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSLVTRSTSLHRVLRLGTCMNIKQMRVCGDRGRYASSTSEENRRIPKIYTKTGDKGFSSTFTGERRPKEDHIFDALGTTDELSSAIGLAREFCIDSGHSFTDQLEKVQCVLQDVGSNIATPRSSARESHITKTKFSSQSVSELEKWIDSFTEELPPLTSFILPSGGKSSAALHVARAVCRRAERCVAPVVRSGETDPEVAKYLNRLSDYLFTVARYAAMKDGNAETIYKRQE", "length": 233 }, "evidence": [ { "id": "A0A8V0ZLS8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLS8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q54W51-1", "protein_name": "Cobalamin adenosyltransferase-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIKISNFRNNNNNNILIINRFFSSKIYTKTGDKGTSALFNGERRKKDDQIFQALGSVDELSSQLGLSKEHLIVLRKEINNEKKELANRVIDEIEQIQCLLLDIGSHIATPSYSEEQFQKRSQFNDFHTTQLENWVDHYTNNHLAPLKNFILPGGGLTSASLHVCRSVCRRSERELITMTNLENEYENNNNNNNNNNNNNNNNNNNEISSPVLRFINRLSDYLFTIARISNKIEGGEESIYRRPSESLSSNNKNNNNSNSSNNNNNNNNNNNDNNKYQRILEKHSTIQD", "length": 291 }, "evidence": [ { "id": "A0A8V0ZLS8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLS8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q96EY8-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "MMAB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVCGLGSRLGLGSRLGLRGCFGAARLLYPRFQSRGPQGVEDGDRPQPSSKTPRIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMKNDPSAESEGL", "length": 250 }, "evidence": [ { "id": "A0A8V0ZLS8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLS8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D273-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "Mmab", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVWLFGGRLGLRGRLSACRLLCPRFQSRGPQGGEDGDRLQPSSTAAKIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFAMELVTEKGHMFAEELQKIQCMLQDVGSALATPRSSAREAHLKHTAFQEGPVLELERWIDKYSSQLPPLKAFILPSGGKSSSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTVARYAAMKEGSQEKIYKKHDV", "length": 237 }, "evidence": [ { "id": "A0A8V0ZLS8", "url": "https://omabrowser.org/oma/group/A0A8V0ZLS8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8" } ], "pmid": "" }, { "name": "corrinoid adenosyltransferase activity", "id": "GO:0008817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8" } ], "pmid": "" }, { "name": "cobalamin binding", "id": "GO:0031419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031419", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cobalamin metabolic process", "id": "GO:0009235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "56796", "name": "", "equation": "cob(I)alamin-[corrinoid adenosyltransferase] + ATP = apo-[corrinoid adenosyltransferase] + adenosylcob(III)alamin + triphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "56796", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56796" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS8" }, { "id": "PF01923", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cobalamin adenosyltransferase-like", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 167, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKV8-1", "uniprot_ac": "A0A8V0ZKV8", "uniprot_id": "A0A8V0ZKV8_CHICK", "mass": { "chemical_mass": 38317.0, "monoisotopic_mass": 38317.0 }, "refseq": {}, "gene_names": [ { "name": "LMAN2L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8" } ] } ], "protein_names": [ { "name": "Lectin, mannose binding 2 like", "type": 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"id": "cd06901", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06901", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035664", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035664", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEH7", "url": "https://www.orthodb.org/?gene=A0A8V0ZEH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKV8", "url": "https://www.orthodb.org/?gene=A0A8V0ZKV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12223:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12223:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-204005", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5694530", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694530", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZEH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGRWRAGLALLAVALGLGGPRAEQMEEHLKREHSLSKPYQGVGSASAGLWELQGNAIVMAQYIRLTPDVQSKWGAVWNRVPCYLRDWEMQVHFKIHGQGKKNLNGDGFAIWYTKDRMQQGPVFGSKDNFLGLGVFVDTYPNEEKQQEAQKRRYSPGNQRVFPYISAMVNNGSLTYDHDRDGRPTELGGCTAMVRNLNHDTFLVIRYVKRRLTVLIDIDGKQEWRDCIDVPGVRLPRGYYFGTSSVTGDLSDNHDIISLKLYQLTVERTPEEERRDKEVYLPVVDNLKLPGTHERPGSLLNRLLLPRGHRLRHRYRGHCVQQVAGAEPEALLLTAAV", "length": 338, "header": "tr|A0A8V0ZKV8-1|A0A8V0ZKV8_CHICK Isoform 1 of Lectin, mannose binding 2 like OS=Gallus gallus OX=9031 GN=LMAN2L PE=1 SV=1 CANONICAL=A0A8V0ZKV8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8/entry#A0A8V0ZEH7-1", "sequence": { "sequence": "MAAGRWRAGLALLAVALGLGGPRAEQMEEHLKREHSLSKPYQGVGSASAGLWELQGNAIVMAQYIRLTPDVQSKWGAVWNRVPCYLRDWEMQVHFKIHGQGKKNLNGDGFAIWYTKDRMQQGPVFGSKDNFLGLGVFVDTYPNEEKQQERVFPYISAMVNNGSLTYDHDRDGRPTELGGCTAMVRNLNHDTFLVIRYVKRRLTEWRDCIDVPGVRLPRGYYFGTSSVTGDLSDNHDIISLKLYQLTVERTPEEERRDKEVYLPVVDNLKLPGMEAPLEPMSGLALFLIVFFSLVAIVFAIVIGVIVYNKWQEQSRKHFY", "length": 319, "header": "tr|A0A8V0ZEH7-1|A0A8V0ZKV8_CHICK Computationally mapped isoform of Lectin, mannose binding 2 like OS=Gallus gallus OX=9031 GN=LMAN2L PE=1 SV=1 CANONICAL=A0A8V0ZKV8-1" }, "locus": { "chromosome": "22", "start_pos": 2993767, "end_pos": 2988692, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049512.1", "url": "https://www.ensembl.org/id/ENSGALT00010049512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029258.1", "url": "https://www.ensembl.org/id/ENSGALP00010029258.1" } ] } }, { "isoform_ac": "A0A8V0ZKV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8/entry#A0A8V0ZKV8-1", "sequence": { "sequence": "MAAGRWRAGLALLAVALGLGGPRAEQMEEHLKREHSLSKPYQGVGSASAGLWELQGNAIVMAQYIRLTPDVQSKWGAVWNRVPCYLRDWEMQVHFKIHGQGKKNLNGDGFAIWYTKDRMQQGPVFGSKDNFLGLGVFVDTYPNEEKQQEAQKRRYSPGNQRVFPYISAMVNNGSLTYDHDRDGRPTELGGCTAMVRNLNHDTFLVIRYVKRRLTVLIDIDGKQEWRDCIDVPGVRLPRGYYFGTSSVTGDLSDNHDIISLKLYQLTVERTPEEERRDKEVYLPVVDNLKLPGTHERPGSLLNRLLLPRGHRLRHRYRGHCVQQVAGAEPEALLLTAAV", "length": 338, "header": "tr|A0A8V0ZKV8-1|A0A8V0ZKV8_CHICK Isoform 1 of Lectin, mannose binding 2 like OS=Gallus gallus OX=9031 GN=LMAN2L PE=1 SV=1 CANONICAL=A0A8V0ZKV8-1" }, "locus": { "chromosome": "22", "start_pos": 2993781, "end_pos": 2988692, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049507.1", "url": "https://www.ensembl.org/id/ENSGALT00010049507.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029255.1", "url": "https://www.ensembl.org/id/ENSGALP00010029255.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-204005", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-204005", "resource": "Reactome", "description": "COPII-mediated vesicle transport" }, { "id": "R-GGA-5694530", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5694530", "resource": "Reactome", "description": "Cargo concentration in the ER" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8" } ], "pmid": "" }, { "name": "COPII-coated ER to Golgi transport vesicle", "id": "GO:0030134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment", "id": "GO:0005793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8" } ], "pmid": "" }, { "name": "D-mannose binding", "id": "GO:0005537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005537", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV8" }, { "id": "PS51328", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51328" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "L-type lectin-like", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 265, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKW7-1", "uniprot_ac": "A0A8V0ZKW7", "uniprot_id": "A0A8V0ZKW7_CHICK", "mass": { "chemical_mass": 59367.0, "monoisotopic_mass": 59367.0 }, "refseq": { "ac": "NP_001186335", "name": "DEP domain-containing protein 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186335" }, "gene_names": [ { "name": "DEPDC7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW7" } ] }, { "name": "DEPDC7", "type": "synonym", "evidence": [ { "id": "NP_001186335", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186335" } ] } ], "protein_names": [ { "name": "DEP domain-containing protein 7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW7/entry#names_and_taxonomy" } ] }, { "name": "DEP domain-containing protein 7", "type": "synonym", "evidence": [ { "id": "NP_001186335", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186335" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CR354003.1, HAEK01021741.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Sep 23, 2021 this sequence version replaced NP_001186335.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186335", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186335" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DEPDC7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW7", "locus": { "chromosome": "5", "start_pos": 6699872, "end_pos": 6708224, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020493", "url": "https://www.ensembl.org/id/ENSGALG00010020493" } ] } } ], "crossref": [ { "id": "A0A8V0ZKW7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKW7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04405", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04405", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04446", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04446", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421593", "url": "https://www.ncbi.nlm.nih.gov/gene/421593", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421593", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421593", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YCTRVSA", "url": "https://omabrowser.org/oma/group/YCTRVSA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEI2", "url": "https://www.orthodb.org/?gene=A0A8V0ZEI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKW7", "url": "https://www.orthodb.org/?gene=A0A8V0ZKW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16206:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16206:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186335", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186335", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATVREKAAALSLSAVCSPATRPPGFSLAQKPFGATYVWSSIISALQTQVEVKKRRQNLKCYHDCFIGSDAVDVVFAHLLQNKYFGDVDISRAKVVRVCQALMDYKVFEAVSRRVFGKDKRSVFEDSSSSLYRFTNVSSQADLDKDYQQCTPQRHQKNTLFNTTPVKAESLEDLWENLSLKPANTPQVNISESLSRRVINEVWREQTIARLLQLVDLPLLDSLLEHQAVKPQLPQPKEDSGYVITSNYLDREILKAFSDSQTDEWLSSAIDCLEYLPDHMVVDISRNLPDQLDKADTWKLLLFENIGRYYGQKKEPLLSHAPEVHSGIAELLVNGKMEQSLEAIQLYLKLLDSQIREEFRRLLYFMAVAAHNSELKLQKESDNRMVVKRTFSKAIINNKSLSRGKTDLLILFLVDHQKDVLKIPGTLHKMVSNKLMALQEGQDPSKIAGYTFCQKLDEREYRLNTEKTTKDELLSLLKAIDEDSKLSEKERKRLLGQFHSSNPSIFMQYFGDRVPNMCM", "length": 519, "header": "tr|A0A8V0ZKW7-1|A0A8V0ZKW7_CHICK Isoform 1 of DEP domain-containing protein 7 OS=Gallus gallus OX=9031 GN=DEPDC7 PE=3 SV=1 CANONICAL=A0A8V0ZKW7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW7/entry#A0A8V0ZEI2-1", "sequence": { "sequence": "MLLPRLGFSLAQKPFGATYVWSSIISALQTQVEVKKRRQNLKCYHDCFIGSDAVDVVFAHLLQNKYFGDVDISRAKVVRVCQALMDYKVFEAVSRRVFGKDKRSVFEDSSSSLYRFTNVSSQADLDKDYQQCTPQRHQKNTLFNTTPVKAESLEDLWENLSLKPANTPQVNISESLSRRVINEVWREQTIARLLQLVDLPLLDSLLEHQAVKPQLPQPKEDSGYVITSNYLDREILKAFSDSQTDEWLSSAIDCLEYLPDHMVVDISRNLPDQLDKADTWKLLLFENIGRYYGQKKEPLLSHAPEVHSGIAELLVNGKMEQSLEAIQLYLKLLDSQIREEFRRLLYFMAVAAHNSELKLQKESDNRMVVKRTFSKAIINNKSLSRGKTDLLILFLVDHQKDVLKIPGTLHKMVSNKLMALQEGQDPSKIAGYTFCQKLDEREYRLNTEKTTKDELLSLLKAIDEDSKLSEKERKRLLGQFHSSNPSIFMQYFGDRVPNMCM", "length": 501, "header": "tr|A0A8V0ZEI2-1|A0A8V0ZKW7_CHICK Computationally mapped isoform of DEP domain-containing protein 7 OS=Gallus gallus OX=9031 GN=DEPDC7 PE=3 SV=1 CANONICAL=A0A8V0ZKW7-1" }, "locus": { "chromosome": "5", "start_pos": 6707520, "end_pos": 6699966, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049521.1", "url": "https://www.ensembl.org/id/ENSGALT00010049521.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029263.1", "url": "https://www.ensembl.org/id/ENSGALP00010029263.1" } ] } }, { "isoform_ac": "A0A8V0ZKW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW7/entry#A0A8V0ZKW7-1", "sequence": { "sequence": "MATVREKAAALSLSAVCSPATRPPGFSLAQKPFGATYVWSSIISALQTQVEVKKRRQNLKCYHDCFIGSDAVDVVFAHLLQNKYFGDVDISRAKVVRVCQALMDYKVFEAVSRRVFGKDKRSVFEDSSSSLYRFTNVSSQADLDKDYQQCTPQRHQKNTLFNTTPVKAESLEDLWENLSLKPANTPQVNISESLSRRVINEVWREQTIARLLQLVDLPLLDSLLEHQAVKPQLPQPKEDSGYVITSNYLDREILKAFSDSQTDEWLSSAIDCLEYLPDHMVVDISRNLPDQLDKADTWKLLLFENIGRYYGQKKEPLLSHAPEVHSGIAELLVNGKMEQSLEAIQLYLKLLDSQIREEFRRLLYFMAVAAHNSELKLQKESDNRMVVKRTFSKAIINNKSLSRGKTDLLILFLVDHQKDVLKIPGTLHKMVSNKLMALQEGQDPSKIAGYTFCQKLDEREYRLNTEKTTKDELLSLLKAIDEDSKLSEKERKRLLGQFHSSNPSIFMQYFGDRVPNMCM", "length": 519, "header": "tr|A0A8V0ZKW7-1|A0A8V0ZKW7_CHICK Isoform 1 of DEP domain-containing protein 7 OS=Gallus gallus OX=9031 GN=DEPDC7 PE=3 SV=1 CANONICAL=A0A8V0ZKW7-1" }, "locus": { "chromosome": "5", "start_pos": 6708155, "end_pos": 6699966, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049527.1", "url": "https://www.ensembl.org/id/ENSGALT00010049527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029265.1", "url": "https://www.ensembl.org/id/ENSGALP00010029265.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421593", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421593", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QPH6-1", "protein_name": "DEP domain-containing protein 7", "gene_name": "Depdc7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATVREKAAALNLSALHSPAQKPPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHHLKRHNDCFIGSEAVDVIYSHLTQNKFFGDVDIPRAKVVRVCQALMDYKVFEAVPTRVFGKDKKPPFEDSSCSLYRFTTIPGQNSQSGNENKVDSPSRYSDTLFQSPEIKSDSLEDLWENLSLKPANSPHINISTRLSPQVINEVWQEETIGRLLQLVDLPFLDSLLKQQEVVPKVPRSKKQPDMVNTSNYLDRGILRAYGDSQEDEWVSAAIDCLEYLPDHMVVDISRNFPEQPDRTDLVKELLFDAIGKYYSTREPLLNHLCDVHNGIAELLVNGKTEIALEATQLFLKLLDSQNREEFRRLLYFMAVAAHPSEFKLQEESDNRMVVKRVFSKAVVNNKNLSKGKTDLLVLFLMDHQKDVFKIPATLHKIVSVKLLAIQKGRDPNKDTGYIYCQRIDESDYSGSKQKKTKEELLNLLKTIDEDSKLSAKEKKKLLGQFHKCHPDIFTEYFGN", "length": 511 }, "evidence": [ { "id": "A0A8V0ZKW7", "url": "https://omabrowser.org/oma/group/A0A8V0ZKW7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BIJ1-1", "protein_name": "DEP domain-containing protein 7", "gene_name": "DEPDC7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATVREKAAALNLSAFQSPVQRPPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHHLKRHNDCFVGSEAVDVIFSHLMQNKYFGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRFTTTPNQDSQLGKENKVCSPSRYADTLFKSSDIRSTSLEALWENLSLKPADSPRVNISATLSPQVINEVWQEETIGRLLQLIDLPLLDSLLKRQEMIPKVSQPKRQLDLVNNRNYLDRGILKAYSDSQEDEWLSSAIDCLEYLPDQMVVDISRNFPEQPDRIDLVKELLFDAISKYYSSREPLLNHLSDVHNGIAELLVNGKTEIALEATQLFLKLLDSQNREEFRRLLYFMAVAAHPSEFKLQQESDNRMVVKRMFSKAIVHNKNLSKGKTDLLVLFLMDHQRDVFKIPGTLHKIVSIKLMDIQKGRDPNRDAGYIYCQRIDRSDYSDHTRKTTKDELLNLLKNIDEDSKLSTKEKKKLLGQFYKCHPDVFIEYFGD", "length": 511 }, "evidence": [ { "id": "A0A8V0ZKW7", "url": "https://omabrowser.org/oma/group/A0A8V0ZKW7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4QR86-1", "protein_name": "DEP domain-containing protein 7", "gene_name": "Depdc7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATVREKAAALDLSALHSPAQRPPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHHLKRHNDCFVGSEAVDVIYSHLTQNKFFGDVDIPRAKVVRVCQALMDYKVFEAVQTRVFGKDKKPAFEDSSCSLYRFTTIPNQDSQLGHENKGTSPSRFSDALFKSSDIKSDSLEDLWENLSLKPTNSPHVSTRLSPQVINEVWQEETIGRLLQLVDLPFLDSLLKQQEVVPKAPQSKRQPDMVNTSNYLDRGILRAYGDSQEDEWISAAIDCLEYLPDQMVVDISRNFPEQPDRTDLVKELLFGAIGKYYSTREPLLNHLSDVHNGIAELLVNGKTEIALEATQLFLKLLDSQNREEFRRLLYFMAVAADPSEFKLQEESDNRMVVKRVFSKAIVNNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLLAIQKGRDPNKDTGYIYCQRIDGREYSSSIQKKTKDQLLSLLKTIDEDSKLSAKEKKKLLGQFHKSHPDIFIEYFGDSF", "length": 511 }, "evidence": [ { "id": "A0A8V0ZKW7", "url": "https://omabrowser.org/oma/group/A0A8V0ZKW7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91WS7-1", "protein_name": "DEP domain-containing protein 7", "gene_name": "Depdc7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVREKAAALNLSALHSPAQRPPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHHLKRHNDCFVGSEAVDVIYSHLTQNKFFGDVDIPRAKVVRVCQALMDYKVFEAVQTRVFGKDKKPTFEDSSCSLYRFTTIPNQDNQLGHENKVHSPSRYSDASFMSSDIKSDSLEDLWENLSLKPASSPHIHISTRLSPQVINEVWQEETIGRLLQLVDLPFLDSLLKQQEVVPKAPQSKRQPDMVNTSNYLDRGILRAYGDSQEDEWISAAIDCLEYLPDQMVVDISRNFPEQPDRTDLVKELLFDAIGRYYSTREPLLNHLYDVHNGIAELLVNGKTEMALEATQLFLKLQDSQNREEFRRLLYFMAVAADPSEFKLQEESDNRMVVKRVFSKAIVNNKNVSKGKTDLLVLFLMDHQKDVFKIPAALHKIVSVKLLAIQKGRDPNKDTGYIYCQRIDESEYSSSTKKKTKDQLLSLLKTIDEDSKLSAKEKKKLLGQFRKTHPDIFTEYFGD", "length": 511 }, "evidence": [ { "id": "A0A8V0ZKW7", "url": "https://omabrowser.org/oma/group/A0A8V0ZKW7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96QD5-1", "protein_name": "DEP domain-containing protein 7", "gene_name": "DEPDC7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATVQEKAAALNLSALHSPAHRPPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHRLKRHNDCFVGSEAVDVIFSHLIQNKYFGDVDIPRAKVVRVCQALMDYKVFEAVPTKVFGKDKKPTFEDSSCSLYRFTTIPNQDSQLGKENKLYSPARYADALFKSSDIRSASLEDLWENLSLKPANSPHVNISATLSPQVINEVWQEETIGRLLQLVDLPLLDSLLKQQEAVPKIPQPKRQSTMVNSSNYLDRGILKAYSDSQEDEWLSAAIDCLEYLPDQMVVEISRSFPEQPDRTDLVKELLFDAIGRYYSSREPLLNHLSDVHNGIAELLVNGKTEIALEATQLLLKLLDFQNREEFRRLLYFMAVAANPSEFKLQKESDNRMVVKRIFSKAIVDNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLMAIQNGRDPNRDAGYIYCQRIDQRDYSNNTEKTTKDELLNLLKTLDEDSKLSAKEKKKLLGQFYKCHPDIFIEHFGD", "length": 511 }, "evidence": [ { "id": "A0A8V0ZKW7", "url": "https://omabrowser.org/oma/group/A0A8V0ZKW7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW7" }, { "id": "PS50186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DEP", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 136, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 398, "end_pos": 400 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLZ1-1", "uniprot_ac": "A0A8V0ZLZ1", "uniprot_id": "A0A8V0ZLZ1_CHICK", "mass": { "chemical_mass": 37768.0, "monoisotopic_mass": 37768.0 }, "refseq": {}, "gene_names": [ { "name": "UBXN10", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1" } ] } ], "protein_names": [ { "name": "UBX domain protein 10", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBXN10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1", "locus": { "chromosome": "21", "start_pos": 4850797, "end_pos": 4839413, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020767", "url": "https://www.ensembl.org/id/ENSGALG00010020767" } ] } } ], "crossref": [ { "id": "A0A8V0ZLZ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17076", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17076", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771670", "url": "https://www.ncbi.nlm.nih.gov/gene/771670", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771670", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771670", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ADSFIWQ", "url": "https://omabrowser.org/oma/group/ADSFIWQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEK3", "url": "https://www.orthodb.org/?gene=A0A8V0ZEK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM04", "url": "https://www.orthodb.org/?gene=A0A8V0ZM04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM04", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSSSNMLPRAGGSPAGRDMGTECHQHGPSPSPQNHPEHCREMAKPMDKRRSKPVSWEAMATAALLNPVPLCCYFPSSTAVSVFQPNAITMHMTRPKSAKGRTRSTFNCSGTTGAYPCAVPSSPAAPHDLQSSRRAPPMKTVFPPGQISPEEIPELLQQVPLRSSSSLNKYRVLPSIGRKGVEGAAEQSGHPDVSWGREDDPKTAAPSGDQGSACRPPESHVPNEEALCAPEKLGRKMRQEGPLLSTLSLEEPLQKESRLLLAIRSPSGQRFEHHFKPTDSLQMVLAIAEHQTATKYERCSIETTEVPRRSFCDLNRSLQECGIPHKSVLCIRQAEQQDLQDTDL", "length": 345, "header": "tr|A0A8V0ZLZ1-1|A0A8V0ZLZ1_CHICK Isoform 1 of UBX domain protein 10 OS=Gallus gallus OX=9031 GN=UBXN10 PE=4 SV=1 CANONICAL=A0A8V0ZLZ1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1/entry#A0A8V0ZEK3-1", "sequence": { "sequence": "MATAALLNPVPLCCYFPSSTAVSVFQPNAITMHMTRPKSAKGRTRSTFNCSGTTGAYPCAVPSSPAAPHDLQSSRRAPPMKTVFPPGQISPEEIPELLQQVPLRSSSSLNKYRVLPSIGRKGVEGAAEQSGHPDVSWGREDDPKTAAPSGDQGSACRPPESHVPNEEALCAPEKLGRKMRQEGPLLSTLSLEEPLQKESRLLLAIRSPSGQRFEHHFKPTDSLQMVLAIAEHQTATKYERCSIETTEVPRRSFCDLNRSLQECGIPHKSVLCIRQAEQQDLQDTDL", "length": 286, "header": "tr|A0A8V0ZEK3-1|A0A8V0ZLZ1_CHICK Computationally mapped isoform of UBX domain protein 10 OS=Gallus gallus OX=9031 GN=UBXN10 PE=4 SV=1 CANONICAL=A0A8V0ZLZ1-1" }, "locus": { "chromosome": "21", "start_pos": 4849641, "end_pos": 4848821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050218.1", "url": "https://www.ensembl.org/id/ENSGALT00010050218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029675.1", "url": "https://www.ensembl.org/id/ENSGALP00010029675.1" } ] } }, { "isoform_ac": "A0A8V0ZLZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1/entry#A0A8V0ZLZ1-1", "sequence": { "sequence": "MRSSSNMLPRAGGSPAGRDMGTECHQHGPSPSPQNHPEHCREMAKPMDKRRSKPVSWEAMATAALLNPVPLCCYFPSSTAVSVFQPNAITMHMTRPKSAKGRTRSTFNCSGTTGAYPCAVPSSPAAPHDLQSSRRAPPMKTVFPPGQISPEEIPELLQQVPLRSSSSLNKYRVLPSIGRKGVEGAAEQSGHPDVSWGREDDPKTAAPSGDQGSACRPPESHVPNEEALCAPEKLGRKMRQEGPLLSTLSLEEPLQKESRLLLAIRSPSGQRFEHHFKPTDSLQMVLAIAEHQTATKYERCSIETTEVPRRSFCDLNRSLQECGIPHKSVLCIRQAEQQDLQDTDL", "length": 345, "header": "tr|A0A8V0ZLZ1-1|A0A8V0ZLZ1_CHICK Isoform 1 of UBX domain protein 10 OS=Gallus gallus OX=9031 GN=UBXN10 PE=4 SV=1 CANONICAL=A0A8V0ZLZ1-1" }, "locus": { "chromosome": "21", "start_pos": 4845557, "end_pos": 4842130, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050200.1", "url": "https://www.ensembl.org/id/ENSGALT00010050200.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029661.1", "url": "https://www.ensembl.org/id/ENSGALP00010029661.1" } ] } }, { "isoform_ac": "A0A8V0ZM04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1/entry#A0A8V0ZM04-1", "sequence": { "sequence": "MANARRAFIFPGRLPWKRNPMPGHLPTAPPSLLQQVSWEAMATAALLNPVPLCCYFPSSTAVSVFQPNAITMHMTRPKSAKGRTRSTFNCSGTTGAYPCAVPSSPAAPHDLQSSRRAPPMKTVFPPGQISPEEIPELLQQVPLRSSSSLNKYRVLPSIGRKGVEGAAEQSGHPDVSWGREDDPKTAAPSGDQGSACRPPESHVPNEEALCAPEKLGRKMRQEGPLLSTLSLEEPLQKESRLLLAIRSPSGQRFEHHFKPTDSLQMVLAIAEHQTATKYERCSIETTEVPRRSFCDLNRSLQECGIPHKSVLCIRQAEQQDLQDTDL", "length": 326, "header": "tr|A0A8V0ZM04-1|A0A8V0ZM04_CHICK Computationally mapped isoform of UBX domain protein 10 OS=Gallus gallus OX=9031 GN=UBXN10 PE=4 SV=1 CANONICAL=A0A8V0ZLZ1-1" }, "locus": { "chromosome": "21", "start_pos": 4845557, "end_pos": 4840208, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050219.1", "url": "https://www.ensembl.org/id/ENSGALT00010050219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029676.1", "url": "https://www.ensembl.org/id/ENSGALP00010029676.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:771670", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771670", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BA51-1", "protein_name": "UBX domain protein 10", "gene_name": "UBXN10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATEAPVNIAPPECSPVGSTATDSFPWQPDSLNMHVTRPKSAKGRTRPRLHKRLGMEGCSGRAPASLPPAIPCESPSSHKPGACTPGSPDQGAPGEIPELLQQAPFGVSSSLNKYPVLPSINRRTLEEGALETVAKKAGSLQLSSAQALSQEEACTMKMGEKDPQAQTCSPERRVLVRTERQTSSRVGDLEEPSDQEPRLLLAIRSPSGRRFVRHFRPADALQTVVAVAEHKNKAAYRHCSIETMGVPRRRFSDLSKSLQDCGIPNKSVLGISQEEGEGWS", "length": 281 }, "evidence": [ { "id": "A0A8V0ZLZ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZLZ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SUN3-1", "protein_name": "UBX domain protein 10", "gene_name": "UBXN10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATEAPVNIAPPECSTAVSTAVDGFLWQRDSLNMHVIRPKSAKGRTRPSLPRPQGPEVCSSRAPSPPPAIPCESPSSQKPGACTPKSPNQWAPDEIPELLQQMPIGSSSSLNKYPVLPSIKRKSLAQGALETTSKKTSALQRSSLQGLYPKETGTLRMSGEDARARPCSLERKFVMQPKKQSSYGAGDLEEPSDQEPRLLLAVRSPSGRRFVRHFRPTDDLQTVVTVAEHKNKATYRHCSIETMEVPRRRFSDLTKSLQECGIAHRSALGIAREDREGWP", "length": 280 }, "evidence": [ { "id": "A0A8V0ZLZ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZLZ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3V606-1", "protein_name": "UBX domain-containing protein 10", "gene_name": "Ubxn10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEAPVNFAPPEHSTVVSTAADSYTWQPSSLRMHVIRPKSAKGRKRPNLHLPQGIGDGSHSGLTSSSPPRSSGSPSNQKREVCATAPASQGAPDEMPELLQQAPIRTASSLNRYPVLPSINRRSSEDGAVDTVSSKTSSLQLSSVQALYQEEARAAVKSSQEDSRTQVCALEKKFIIRTKRQSSSRASNMEEPSDEEPRLLLAVRSPSGQRFVRYFRPSDDLQTVLEVAEQKNKATYQHCIVETMEVPRRRFSDLTKSLQECGILHKSVLGISQEEGEGWP", "length": 282 }, "evidence": [ { "id": "A0A8V0ZLZ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZLZ1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0P3Z8-1", "protein_name": "UBX domain-containing protein 10", "gene_name": "ubxn10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHVTRPKSSKGRSRPMITNSSMIYTPSQPSALSPQPPAAAKTKDKSNQSLRSRAILRRSSQPTTDILTEAYDRPPEEPVSLNRYRVLPSIEKKTSTDNQKCSQCVSRHRKCQHTNARLDVVSDSTPPEESDLLLAIRTPCGQRFKRSFRPSDQLKGVLSAAEAEFGDRFDNCIIETMDVPRRTFSNLTMTLAQCGVLNKSVLCISHDDSEMDLT", "length": 214 }, "evidence": [ { "id": "A0A8V0ZLZ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZLZ1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BG34-1", "protein_name": "UBX domain-containing protein 10", "gene_name": "Ubxn10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIEAPVNFAPPERSTVVSTAGDSSTWQPSSLRMHVIRPKSAKGRKRPNLHRPQGMGDGSPSALSSSPPPRSSGSPSNQKPGVCATVSTSQGAPDEMPELLLQQAPTRTASSLNRYPVLPSINRRSLEVGAVDTVASKTSSLQLSSVQALYQEDSSQEDSRTQVCALEKKFIIRTKRQSSSRASNIEEPSDEEPRLLLAVRSPSGQRFVRYFRPSDDLQTVLEVAEQKNKATYQHCSIETMEVPRRRFSDLTKSLQECGILHKSVLGISQEEGEAWP", "length": 277 }, "evidence": [ { "id": "A0A8V0ZLZ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZLZ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96LJ8-1", "protein_name": "UBX domain-containing protein 10", "gene_name": "UBXN10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATEAPVNIAPPECSTVVSTAVDSLIWQPNSLNMHMIRPKSAKGRTRPSLQKSQGVEVCAHHIPSPPPAIPYELPSSQKPGACAPKSPNQGASDEIPELQQQVPTGASSSLNKYPVLPSINRKNLEEEAVETVAKKASSLQLSSIRALYQDETGTMKTSEEDSRARACAVERKFIVRTKKQGSSRAGNLEEPSDQEPRLLLAVRSPTGQRFVRHFRPTDDLQTIVAVAEQKNKTSYRHCSIETMEVPRRRFSDLTKSLQECRIPHKSVLGISLEDGEGWP", "length": 280 }, "evidence": [ { "id": "A0A8V0ZLZ1", "url": "https://omabrowser.org/oma/group/A0A8V0ZLZ1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLZ1" }, { "id": "PS50033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBX", "eco_id": "ECO_0000259", "start_pos": 255, "end_pos": 332, "start_aa": "Gln", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 316, "end_pos": 318 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZM16-1", "uniprot_ac": "A0A8V0ZM16", "uniprot_id": "A0A8V0ZM16_CHICK", "mass": { "chemical_mass": 132843.0, "monoisotopic_mass": 132843.0 }, "refseq": { "ac": "XP_015145010", "name": "partitioning defective 3 homolog B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145010" }, "gene_names": [ { "name": "PARD3B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ] }, { "name": "PARD3B", "type": "synonym", "evidence": [ { "id": "XP_015145010", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145010" } ] } ], "protein_names": [ { "name": "Partitioning defective 3 homolog B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#names_and_taxonomy" } ] }, { "name": "PAR3-beta", "type": "synonym", "evidence": [ { "id": "A0A8V0ZM16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#names_and_taxonomy" } ] }, { "name": "Partitioning defective 3-like protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZM16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#names_and_taxonomy" } ] }, { "name": "partitioning defective 3 homolog B", "type": "synonym", "evidence": [ { "id": "XP_015145010", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145010" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015145010.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145010" } ] }, { "annotation": "Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZEP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP1#function" }, { "database": "UniProtKB", "id": "ARBA00055389", "url": "https://www.uniprot.org/uniprotkb/ARBA00055389#function" }, { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16#function" }, { "database": "UniProtKB", "id": "A0A8V0ZK18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK18#function" }, { "database": "UniProtKB", "id": "A0A8V0ZK28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK28#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP3#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP9#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM05#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PARD3B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16", "locus": { "chromosome": "7", "start_pos": 12382284, "end_pos": 12747252, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021734", "url": "https://www.ensembl.org/id/ENSGALG00010021734" } ] } } ], "crossref": [ { "id": "A0A8V0ZM16", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZM16", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06691", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06691", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23058", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23058", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426120", "url": "https://www.ncbi.nlm.nih.gov/gene/426120", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426120", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426120", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFQHIKA", "url": "https://omabrowser.org/oma/group/QFQHIKA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEP1", "url": "https://www.orthodb.org/?gene=A0A8V0ZEP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK18", "url": "https://www.orthodb.org/?gene=A0A8V0ZK18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK28", "url": "https://www.orthodb.org/?gene=A0A8V0ZK28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLP3", "url": "https://www.orthodb.org/?gene=A0A8V0ZLP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLP9", "url": "https://www.orthodb.org/?gene=A0A8V0ZLP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLQ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZLQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLS0", "url": "https://www.orthodb.org/?gene=A0A8V0ZLS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM05", "url": "https://www.orthodb.org/?gene=A0A8V0ZM05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM16", "url": "https://www.orthodb.org/?gene=A0A8V0ZM16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16484", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16484", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16484:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16484:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145010", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVRDLTQQALQRYRKAQEKDPTYWVNIHHLEYTDGGILDPDDVLADVVEDKDKLIAVYDEQEPHRKSDGTNGNVTDRSSPDLFEAEVAAQLAAFQPIGGEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHLSDLSHKHAVAGASQVSFEDGEMNLAGPTELLSSQRARLPVSEMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFIRGIEENSRSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVVLEVLPPYNREQYEKSAIAPLCFLHNDEEVPKTKIPPPVHPKPTLKTINLSGAGSLDAGVLATLQAKSPNLPRLGRKSSSPSLSPLMGFGNKKNAKKIKIDLKKGPEGLGFTVVTRDSSVHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQQELVAMLRSTKQGETVCLIVARQEEAFLPRELKGEPNCSALSPETTEQLTFEIPLNDSGSAGLGVSLKGNKSRETGADLGIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQLVVLRRLEAQTEERLDQGVYQKSAFDGSHNFAAISRRNGAVLQQFVNSGPQERVQDLPVSDCGNCENETPPPLPPHPSEDLLSEDHNHSPTINSAVYLADQHINFTSLTPAKQSESINLKASKSMDLVADESKVGSLAGHRSDASSKDFGPTLGLKKSSSLESLQTAVAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVEEDGFSDKSSHSGQEAQNMESVPPGNPEIEDVETKVKKDKKSREKEKKKEKGKTKIKEKKRKEENEDPEKKKKKGFGVMLRFGKKKEDKSGKADQKGNPKHDILKEEDLEKMKDERERIGAKHQELRQKQLRGLLDYSTGPGGPDIDDDEVDPNYARVNHFREAYPAASIYRPSSPAVAETFVYPRDSSSTAMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQARREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHYEGMERQYASLPRRGPAEPLEYLTGPRVIYKERDLPYYQGGGQPVVHPSKGNYIHAPDTRVAELRYPQYYPAQSIPNQHKGPFRQDVPPSPPQPHRAPAYNEIVRHRGTSPDQYQYRQQDPRQKNPMTAAV", "length": 1201, "header": "tr|A0A8V0ZM16-1|A0A8V0ZM16_CHICK Isoform 1 of Partitioning defective 3 homolog B OS=Gallus gallus OX=9031 GN=PARD3B PE=3 SV=1 CANONICAL=A0A8V0ZM16-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#A0A8V0ZEP1-1", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVRDLTQQALQRYRKAQEKDPTYWVNIHHLEYTDGGILDPDDVLADVVEDKDKLIAVYDEQEPHRKSDGTNGNVTDRSSPDLFEAEVAAQLAAFQPIGGEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHLSDLSHKHAVAGASQVSFEDGEMNLAGPTELLSSQRARLPVSEMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFIRGIEENSRSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVVLEVLPPYNREQYEKSAIAPLCFLHNDEEVPKTKIPPPVHPKPTLKTINLSGAGSLDAGVLATLQAKSPNLPRLGRKSSSPSLSPLMGFGNKKNAKKIKIDLKKGPEGLGFTVVTRDSSVHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQQELVAMLRSTKQGETVCLIVARQEEAFLPRELKGEPNCSALSPETTEQLTFEIPLNDSGSAGLGVSLKGNKSRETGADLGIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQLVVLRRLEAQTEERLDQGVYQKSAFDGSHNFAAISRRNGAVLQQFVNSGPQERVQVADESKVGSLAGHRSDASSKDFGPTLGLKKSSSLESLQTAVAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVEEDGFSDKSSHSGQEAQNMESVPPGNPEIEDVETKVKKDKKSREKEKKKEKGKTKIKEKKRKEENEDPEKKKKKGFGVMLRFGKKKEDKSGKADQKGNPKHDILKEEDLEKMKDERERIGAKHQELRQKQLRGLLDYSTGPGGPDIDDDEVDPNYARVNHFREAYPAASIYRPSSPAVAETFVYPRDSSSTAMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQARREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHYEGMERQYASLPRRGPAEPLEYLTGPRVIYKERDLPYYQGGGQPVVHPSKGNYIHAPDTRVAELRYPQYYPAQSIPNQHKGPFRQDVPPSPPQPHRAPAYNEIVRHRGTSPDQYQYRQQDPRQKNPMTAAV", "length": 1129, "header": "tr|A0A8V0ZEP1-1|A0A8V0ZM16_CHICK Computationally mapped isoform of Partitioning defective 3 homolog B OS=Gallus gallus OX=9031 GN=PARD3B PE=3 SV=1 CANONICAL=A0A8V0ZM16-1" }, "locus": { "chromosome": "7", "start_pos": 12747139, "end_pos": 12383288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052855.1", "url": "https://www.ensembl.org/id/ENSGALT00010052855.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031761.1", "url": "https://www.ensembl.org/id/ENSGALP00010031761.1" } ] } }, { "isoform_ac": "A0A8V0ZK18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#A0A8V0ZK18-1", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVRDLTQQALQRYRKAQEKDPTYWVNIHHLEYTDGGILDPDDVLADVVEDKDKLIAVYDEQEPHRKSDGTNGNVTDRSSPDLFEAEVAAQLAAFQPIGGEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHLSDLSHKHAVAGASQVSFEDGEMNLAGPTELLSSQRARLPVSEMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFIRGIEENSRSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVVLEVLPPYNREQYEKSAIAPLCFLHNDEEVPKTKIPPPVHPKPTLKTINLSGAGSLDAGVLATLQAKSPNLPRLGRKSSSPSLSPLMGFGNKKNAKKIKIDLKKGPEGLGFTVVTRDSSVHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQQELVAMLRSTKQGETVCLIVARQEEAFLPRELKGEPNCSALSPETTEQLTFEIPLNDSGSAGLGVSLKGNKSRETGADLGIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQLVVLRRLEAQTEERLDQGVYQKSAFDGSHNFAAISRRNGAVLQQFVNSGPQERVQDLPVSDCGNCENETPPPLPPHPSEDLLSEDHNHSPTINSAVYLADQHINFTSLTPAKQSESINLKASKSMDLVADESKVGSLAGHRSDASSKDFGPTLGLKKSSSLESLQTAVAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVEEDGFSDKSSHSGQEAQNMESVPPGNPEIEDVETKVKKDKKSREKEKKKEKGKTKIKEKKRKEENEDPEKKKKKGFGVMLRFGKKKEDKSGKADQKGNPKHDILKEEDLEKMKDERERIGAKHQELRQKQLRGLLDYSTGPGGPDIDDDEVDPNYARVNHFREAYPAASIYRPSSPAVAETFVYPRDSSSTAMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQARREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHYEGMERQYASLPRHFIFGRTSSTFHKL", "length": 1097, "header": "tr|A0A8V0ZK18-1|A0A8V0ZK18_CHICK Computationally mapped isoform of Partitioning defective 3 homolog B OS=Gallus gallus OX=9031 GN=PARD3B PE=3 SV=1 CANONICAL=A0A8V0ZM16-1" }, "locus": { "chromosome": "7", "start_pos": 12747139, "end_pos": 12396096, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052827.1", "url": "https://www.ensembl.org/id/ENSGALT00010052827.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031733.1", "url": "https://www.ensembl.org/id/ENSGALP00010031733.1" } ] } }, { "isoform_ac": "A0A8V0ZK28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#A0A8V0ZK28-1", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVRDLTQQALQRYRKAQEKDPTYWVNIHHLEYTDGGILDPDDVLADVVEDKDKLIAVYDEQEPHRKSDGTNGNVTDRSSPDLFEAEVAAQLAAFQPIGGEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHLSDLSHKHAVAGASQVSFEDGEMNLAGPTELLSSQRARLPVSEMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFIRGIEENSRSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVVLEVLPPYNREQYEKSAIAPLCFLHNDEEVPKTKIPPPVHPKPTLKTINLSGAGSLDAGVLATLQAKSPNLPRLGRKSSSPSLSPLMGFGNKKNAKKIKIDLKKGPEGLGFTVVTRDSSVHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQQELVAMLRSTKQGETVCLIVARQEEAFLPRELKGEPNCSALSPETTEQLTFEIPLNDSGSAGLGVSLKGNKSRETGADLGIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQLVVLRRLEAQTEERLDQGVYQKSAFDGSHNFAAISRRNGAVLQQFVNSGPQERVQDLPVSDCGNCENETPPPLPPHPSEDLLSEDHNHSPTINSAVYLADQHINFTSLTPAKQSESINLKASKSMDLVADESKVGSLAGHRSDASSKDFGPTLGLKKSSSLESLQTAVAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVEEDGFSDKSSHSGQEAQNMESVPPGNPEIEDVETKVKKDKKSREKEKKKEKGKTKIKEKKRKEENEDPEKKKKKGFGVMLRFGKKKEDKSGKADQKGNPKHDILKEEDLEKMKDERERIGAKHQELRQKQLRGLLDYSTGPGGPDIDDDEVDPNYARVNHFREAYPAASIYRPSSPAVAETFVYPRDSSSTAMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQARREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHYEGMERQYASLPRTGLPESSWQWLCWELSSLAGWQSTSHSAATSRPAL", "length": 1118, "header": "tr|A0A8V0ZK28-1|A0A8V0ZK28_CHICK Computationally mapped isoform of Partitioning defective 3 homolog B OS=Gallus gallus OX=9031 GN=PARD3B PE=3 SV=1 CANONICAL=A0A8V0ZM16-1" }, "locus": { "chromosome": "7", "start_pos": 12747139, "end_pos": 12385781, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052838.1", "url": "https://www.ensembl.org/id/ENSGALT00010052838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031743.1", "url": "https://www.ensembl.org/id/ENSGALP00010031743.1" } ] } }, { "isoform_ac": "A0A8V0ZLP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#A0A8V0ZLP3-1", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVRDLTQQALQRYRKAQEKDPTYWVNIHHLEYTDGGILDPDDVLADVVEDKDKLIAVYDEQEPHRKSDGTNGNVTDRSSPDLFEAEVAAQLAAFQPIGGEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHLSDLSHKHAVAGASQVSFEDGEMNLAGPTELLSSQRARLPVSEMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFIRGIEENSRSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVVLEVLPPYNREQYEKSAIAPLCFLHNDEEVPKTKIPPPVHPKPTLKTINLSGAGSLDAGVLATLQAKSPNLPRLGRKSSSPSLSPLMGFGNKKNAKKIKIDLKKGPEGLGFTVVTRDSSVHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQQELVAMLRSTKQGETVCLIVARQEEAFLPRELKGEPNCSALSPETTEQLTFEIPLNDSGSAGLGVSLKGNKSRETGADLGIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQLVVLRRLEAQTEERLDQGVYQKSAFDGSHNFAAISRRNGAVLQQFVNSGPQERVQDLPVSDCGNCENETPPPLPPHPSEDLLSEDHNHSPTINSAVYLADQHINFTSLTPAKQSESINLKASKSMDLVADESKVGSLAGHRSDASSKDFGPTLGLKKSSSLESLQTAVAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVEEDGFSDKSSHSGQEAQNMESVPPGNPEIEDVETKVKKDKKSREKEKKKEKGKTKIKEKKRKEENEDPEKKKKKGFGVMLRFGKKKEDKSGKADQKGNPKHDILKEEDLEKMKDERERIGAKHQELRQKQLRGLLDYSTGPGGPDIDDDEVDPNYARVNHFREAYPAASIYRPSSPAVAETFVYPRDSSSTAMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQARREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHYEGMERQYASLPRKPLTLNMSARAVIRL", "length": 1098, "header": "tr|A0A8V0ZLP3-1|A0A8V0ZLP3_CHICK Computationally mapped isoform of Partitioning defective 3 homolog B OS=Gallus gallus OX=9031 GN=PARD3B PE=3 SV=1 CANONICAL=A0A8V0ZM16-1" }, "locus": { "chromosome": "7", "start_pos": 12747139, "end_pos": 12408200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052824.1", "url": "https://www.ensembl.org/id/ENSGALT00010052824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031730.1", "url": "https://www.ensembl.org/id/ENSGALP00010031730.1" } ] } }, { "isoform_ac": "A0A8V0ZLP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#A0A8V0ZLP9-1", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVRDLTQQALQRYRKAQEKDPTYWVNIHHLEYTDGGILDPDDVLADVVEDKDKLIAVYDEQEPHRKSDGTNGNVTDRSSPDLFEAEVAAQLAAFQPIGGEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHLSDLSHKHAVAGASQVSFEDGEMNLAGPTELLSSQRARLPVSEMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFIRGIEENSRSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVVLEVLPPYNREQYEKSAIAPLCFLHNDEEVPKTKIPPPVHPKPTLKTINLSGAGSLDAGVLATLQAKSPNLPRLGRKSSSPSLSPLMGFGNKKNAKKIKIDLKKGPEGLGFTVVTRDSSVHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQQELVAMLRSTKQGETVCLIVARQEEAFLPRELKGEPNCSALSPETTEQLTFEIPLNDSGSAGLGVSLKGNKSRETGADLGIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQLVVLRRLEAQTEERLDQGVYQKSAFDGSHNFAAISRRNGAVLQQFVNSGPQERVQDLPVSDCGNCENETPPPLPPHPSEDLLSEDHNHSPTINSAVYLADQHINFTSLTPAKQSESINLKASKSMDLVADESKVGSLAGHRSDASSKDFGPTLGLKKSSSLESLQTAVAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVEEDGFSDKSSHSGQEAQNMESVPPGNPEIEDVETKVKKDKKSREKEKKKEKGKTKIKEKKRKEENEDPEKKKKKGFGVMLRFGKKKEDKSGKADQKGNPKHDILKEEDLEKMKDERERIGAKHQELRQKQLRGLLDYSTGPGGPDIDDDEVDPNYARVNHFREAYPAASIYRPSSPAVAETFVYPRDSSSTAMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQARREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHYEGMERQYASLPSITRTFTAGEESKEELPGQECKIQLVLLDGRACRRS", "length": 1118, "header": "tr|A0A8V0ZLP9-1|A0A8V0ZLP9_CHICK Computationally mapped isoform of Partitioning defective 3 homolog B OS=Gallus gallus OX=9031 GN=PARD3B PE=3 SV=1 CANONICAL=A0A8V0ZM16-1" }, "locus": { "chromosome": "7", "start_pos": 12747139, "end_pos": 12393672, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052829.1", "url": "https://www.ensembl.org/id/ENSGALT00010052829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031735.1", "url": "https://www.ensembl.org/id/ENSGALP00010031735.1" } ] } }, { "isoform_ac": "A0A8V0ZLQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#A0A8V0ZLQ5-1", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVRDLTQQALQRYRKAQEKDPTYWVNIHHLEYTDGGILDPDDVLADVVEDKDKLIAVYDEQEPHRKSDGTNGNVTDRSSPDLFEAEVAAQLAAFQPIGGEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHLSDLSHKHAVAGASQVSFEDGEMNLAGPTELLSSQRARLPVSEMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFIRGIEENSRSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVVLEVLPPYNREQYEKSAIAPLCFLHNDEEVPKTKIPPPVHPKPTLKTINLSGAGSLDAGVLATLQAKSPNLPRLGRKSSSPSLSPLMGFGNKKNAKKIKIDLKKGPEGLGFTVVTRDSSVHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQQELVAMLRSTKQGETVCLIVARQEEAFLPRELKGEPNCSALSPETTEQLTFEIPLNDSGSAGLGVSLKGNKSRETGADLGIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQLVVLRRLEAQTEERLDQGVYQKSAFDGSHNFAAISRRNGAVLQQFVNSGPQERVQDLPVSDCGNCENETPPPLPPHPSEDLLSEDHNHSPTINSAVYLADQHINFTSLTPAKQSESINLKASKSMDLVADESKVGSLAGHRSDASSKDFGPTLGLKKSSSLESLQTAVAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVEEDGFSDKSSHSGQEAQNMESVPPGNPEIEDVETKVKKDKKSREKEKKKEKGKTKIKEKKRKEENEDPEKKKKKGFGVMLRFGKKKEDKSGKADQKGNPKHDILKEEDLEKMKDERERIGAKHQELRQKQLRGLLDYSTGPGGPDIDDDEVDPNYARVNHFREAYPAASIYRPSSPAVAETFVYPRDSSSTAMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQARREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHYEGMERQYASLPSIALKI", "length": 1088, "header": "tr|A0A8V0ZLQ5-1|A0A8V0ZLQ5_CHICK Computationally mapped isoform of Partitioning defective 3 homolog B OS=Gallus gallus OX=9031 GN=PARD3B PE=3 SV=1 CANONICAL=A0A8V0ZM16-1" }, "locus": { "chromosome": "7", "start_pos": 12747139, "end_pos": 12386016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052834.1", "url": "https://www.ensembl.org/id/ENSGALT00010052834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031740.1", "url": "https://www.ensembl.org/id/ENSGALP00010031740.1" } ] } }, { "isoform_ac": "A0A8V0ZLS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#A0A8V0ZLS0-1", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVRDLTQQALQRYRKAQEKDPTYWVNIHHLEYTDGGILDPDDVLADVVEDKDKLIAVYDEQEPHRKSDGTNGNVTDRSSPDLFEAEVAAQLAAFQPIGGEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHLSDLSHKHAVAGASQVSFEDGEMNLAGPTELLSSQRARLPVSEMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFIRGIEENSRSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVVLEVLPPYNREQYEKSAIAPLCFLHNDEEVPKTKIPPPVHPKPTLKTINLSGAGSLDAGVLATLQAKSPNLPRLGRKSSSPSLSPLMGFGNKKNAKKIKIDLKKGPEGLGFTVVTRDSSVHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQQELVAMLRSTKQGETVCLIVARQEEAFLPRELKGEPNCSALSPETTEQLTFEIPLNDSGSAGLGVSLKGNKSRETGADLGIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQLVVLRRLEAQTEERLDQGVYQKSAFDGSHNFAAISRRNGAVLQQFVNSGPQERVQDLPVSDCGNCENETPPPLPPHPSEDLLSEDHNHSPTINSAVYLADQHINFTSLTPAKQSESINLKASKSMDLVADESKVGSLAGHRSDASSKDFGPTLGLKKSSSLESLQTAVAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVEEDGFSDKSSHSGQEAQNMESVPPGNPEIEDVETKVKKDKKSREKEKKKEKGKTKIKEKKRKEENEDPEKKKKKGFGVMLRFGKKKEDKSGKADQKGNPKHDILKEEDLEKMKDERERIGAKHQELRQKQLRGLLDYSTGPGGPDIDDDEVDPNYARVNHFREAYPAASIYRPSSPAVAETFVYPRDSSSTAMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQARREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHYEGMERQYASLPSNRQITHAEMEHRHWVLPLKVNLLLPASLKRPAACSSHFSPALNIHWPAVTRGHPQGFSSATDVDLQSHWNI", "length": 1154, "header": "tr|A0A8V0ZLS0-1|A0A8V0ZLS0_CHICK Computationally mapped isoform of Partitioning defective 3 homolog B OS=Gallus gallus OX=9031 GN=PARD3B PE=3 SV=1 CANONICAL=A0A8V0ZM16-1" }, "locus": { "chromosome": "7", "start_pos": 12747139, "end_pos": 12383614, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052849.1", "url": "https://www.ensembl.org/id/ENSGALT00010052849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031755.1", "url": "https://www.ensembl.org/id/ENSGALP00010031755.1" } ] } }, { "isoform_ac": "A0A8V0ZM05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#A0A8V0ZM05-1", "sequence": { "sequence": "MKKDPTYWVNIHHLEYTDGGILDPDDVLADVVEDKDKLIAVYDEQEPHRKSDGTNGNVTDRSSPDLFEAEVAAQLAAFQPIGGEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHLSDLSHKHAVAGASQVSFEDGEMNLAGPTELLSSQRARLPVSEMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFIRGIEENSRSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVVLEVLPPYNREQYEKSAIAPLCFLHNDEEVPKTKIPPPVHPKPTLKTINLSGAGSLDAGVLATLQAKSPNLPRLGRKSSSPSLSPLMGFGNKKNAKKIKIDLKKGPEGLGFTVVTRDSSVHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQQELVAMLRSTKQGETVCLIVARQEEAFLPRELKGEPNCSALSPETTEQLTFEIPLNDSGSAGLGVSLKGNKSRETGADLGIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQLVVLRRLEAQTEERLDQGVYQKSAFDGSHNFAAISRRNGAVLQQFVNSGPQERVQDLPVSDCGNCENETPPPLPPHPSEDLLSEDHNHSPTINSAVYLADQHINFTSLTPAKQSESINLKASKSMDLVADESKVGSLAGHRSDASSKDFGPTLGLKKSSSLESLQTAVAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVEEDGFSDKSSHSGQEAQNMESVPPGNPEIEDVETKVKKDKKSREKEKKKEKGKTKIKEKKRKEENEDPEKKKKKGFGVMLRFGKKKEDKSGKADQKGNPKHDILKEEDLEKMKDERERIGAKHQELRQKQLRGLLDYSTGPGGPDIDDDEVDPNYARVNHFREAYPAASIYRPSSPAVAETFVYPRDSSSTAMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQARREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHYEGMERQYASLPRRGPAEPLEYLTGPRVIYKERDLPYYQGGGQPVVHPSKGNYIHAPDTRVAELRYPQYYPAQSIPNQHKGPFRQDVPPSPPQPHRAPAYNEIVRHRGTSPDQYQYRQQDPRQKNPMTAAV", "length": 1164, "header": "tr|A0A8V0ZM05-1|A0A8V0ZM05_CHICK Computationally mapped isoform of Partitioning defective 3 homolog B OS=Gallus gallus OX=9031 GN=PARD3B PE=3 SV=1 CANONICAL=A0A8V0ZM16-1" }, "locus": { "chromosome": "7", "start_pos": 12744780, "end_pos": 12383288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052843.1", "url": "https://www.ensembl.org/id/ENSGALT00010052843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031749.1", "url": "https://www.ensembl.org/id/ENSGALP00010031749.1" } ] } }, { "isoform_ac": "A0A8V0ZM16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16/entry#A0A8V0ZM16-1", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVRDLTQQALQRYRKAQEKDPTYWVNIHHLEYTDGGILDPDDVLADVVEDKDKLIAVYDEQEPHRKSDGTNGNVTDRSSPDLFEAEVAAQLAAFQPIGGEIEVTPSALKLGMPLLVRRSSDPALGPPADFHPSASHLSDLSHKHAVAGASQVSFEDGEMNLAGPTELLSSQRARLPVSEMTKTVEISGEGGPLGIHVVPFFSSLSGRMLGLFIRGIEENSRSRRDGLFHENECIVKINNVDLIDKTFAQAQDIFRQAMKFQSVVLEVLPPYNREQYEKSAIAPLCFLHNDEEVPKTKIPPPVHPKPTLKTINLSGAGSLDAGVLATLQAKSPNLPRLGRKSSSPSLSPLMGFGNKKNAKKIKIDLKKGPEGLGFTVVTRDSSVHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDITGRTQQELVAMLRSTKQGETVCLIVARQEEAFLPRELKGEPNCSALSPETTEQLTFEIPLNDSGSAGLGVSLKGNKSRETGADLGIFIKSVIHGGAAFKDGRLRVNDQLVAVNGESLLGKSNHEAMETLRRSMSMEGNIRGRIQLVVLRRLEAQTEERLDQGVYQKSAFDGSHNFAAISRRNGAVLQQFVNSGPQERVQDLPVSDCGNCENETPPPLPPHPSEDLLSEDHNHSPTINSAVYLADQHINFTSLTPAKQSESINLKASKSMDLVADESKVGSLAGHRSDASSKDFGPTLGLKKSSSLESLQTAVAEVRKNELPFHRPRPHVVRGRGCNESFRAAIDKSYDGPEDVEEDGFSDKSSHSGQEAQNMESVPPGNPEIEDVETKVKKDKKSREKEKKKEKGKTKIKEKKRKEENEDPEKKKKKGFGVMLRFGKKKEDKSGKADQKGNPKHDILKEEDLEKMKDERERIGAKHQELRQKQLRGLLDYSTGPGGPDIDDDEVDPNYARVNHFREAYPAASIYRPSSPAVAETFVYPRDSSSTAMEREHLEGLYAKINKQHYPQVPGDSGCAGGGNADRIQKLRKEYHQARREGLPFYEDDEGRTQLSDCDHRWVPGKGPDGSSYSLHYEGMERQYASLPRRGPAEPLEYLTGPRVIYKERDLPYYQGGGQPVVHPSKGNYIHAPDTRVAELRYPQYYPAQSIPNQHKGPFRQDVPPSPPQPHRAPAYNEIVRHRGTSPDQYQYRQQDPRQKNPMTAAV", "length": 1201, "header": "tr|A0A8V0ZM16-1|A0A8V0ZM16_CHICK Isoform 1 of Partitioning defective 3 homolog B OS=Gallus gallus OX=9031 GN=PARD3B PE=3 SV=1 CANONICAL=A0A8V0ZM16-1" }, "locus": { "chromosome": "7", "start_pos": 12747139, "end_pos": 12383288, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052853.1", "url": "https://www.ensembl.org/id/ENSGALT00010052853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031759.1", "url": "https://www.ensembl.org/id/ENSGALP00010031759.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426120", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426120", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M2X6-1", "protein_name": "Partitioning defective 3 homolog B", "gene_name": "Pard3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVSELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILDPDDVLADVVEDKDKLIAVFDEQEPLQKIESPSGNPVDRQSPDAFDTEVAAQLAAFKPIGGEIVVTPSALKLGTPLLVRRSSDPAPGPHADAQPSTASPSGQSLKPVVLDSAQNLENRDVMNGEQTGLLMLHKTKNELSDMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFIRGIEENSRCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVVLHVLLPQNREQYEKSVIGQLNIFGNNDSASRTKAPPPTRGKAGLKAVNPTRANSPEGEESPSPQQSKSPRVPRLGRKPSSPSLSPLMGFGSKKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLVIARQEGSFLPRELKGEPDCYALSLESSEQLTLEIPLNDSGSAGLGVSLKGNKSRETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRLERPLEEISECGALSRPCFENCQEALSASRRNDSSLLYPCGTYSPQDKRKDLLLPSDGWAENEVPPSPPPHPSLEWGLEDFSHSSRVDSTGYFPDQHVNFRIVTPVGQPESINLKASKSMDLVPDESKVQSLADRRSDSPGKDFGPTLGLKKSSSLESLQTAVAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEAEADGLSDKSSHSGHTALNCESAPQGNPELDDVENKAKNVKKTKEKEKKKGKGKMKVKEKKQKEEHEDTERKMKRKGFGAMLRFGKKKDDKVGKTEQKGTQKSGHPGEEELERMKEERERIGAKHQELREKQARGLVDYATVATGPVHDIDDDEMDPNYARVNHFREPCTSANVFRSPSPPRAGTLGYPRDGRPLSPDHLEGLYAKVNKPYHPPALADSGRPMAGTTDRIQKLRKEYYQARREGFLLYEDEEGVTRPSDYDLHWVSGKGPDGSAHNLRFEGMERQYASLPRGGSADPVDYLTASPRGRYNERELPYYPGPHPVHSPRGSYPRPPDLRVTDLRYPQYYPPPPAHQHKGPFRQDVPPSPPQHQRVPVYQEMGRAGPRGGSPDQYPYRNQDPRQKNPMTAAV", "length": 1203 }, "evidence": [ { "id": "A0A8V0ZM16", "url": "https://omabrowser.org/oma/group/A0A8V0ZM16/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TEW8-1", "protein_name": "Partitioning defective 3 homolog B", "gene_name": "PARD3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILDPDDVLADVVEDKDKLIAVFEEQEPLHKIESPSGNPADRQSPDAFETEVAAQLAAFKPIGGEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPSASHPGGQSLKLVVPDSTQNLEDREVLNGVQTELLTSPRTKDTLSDMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFIRGIEDNSRSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQNREQYEKSVIGSLNIFGNNDGVLKTKVPPPVHGKSGLKTANLTGTDSPETDASASLQQNKSPRVPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQEGHFLPRELKGEPDCCALSLETSEQLTFEIPLNDSGSAGLGVSLKGNKSRETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRPERPMEDPAECGAFSKPCFENCQNAVTTSRRNDNSILHPLGTCSPQDKQKGLLLPNDGWAESEVPPSPTPHSALGLGLEDYSHSSGVDSAVYFPDQHINFRSVTPARQPESINLKASKSMDLVPDESKVHSLAGQKSESPSKDFGPTLGLKKSSSLESLQTAVAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIEADGLSDKSSHSGQGALNCESAPQGNSELEDMENKARKVKKTKEKEKKKEKGKLKVKEKKRKEENEDPERKIKKKGFGAMLRFGKKKEDKGGKAEQKGTLKHGGLREEELEKMKEERERIGAKHQELREKQARGLLDYATGAIGSVYDMDDDEMDPNYARVNHFREPCTSANVFRSPSPPRAGPFGYPRDGHPLSPERDHLEGLYAKVNKPYHPLVPADSGRPTGGSTDRIQKLRKEYYQARREGFPLYEDDEGRARPSEYDLLWVPGRGPDGNAHNLRFEGMERQYASLPRGGPADPVDYLPAAPRGLYKERELPYYPGAHPMHPPKGSYPRPTELRVADLRYPQHYPPPPAPQHKGPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV", "length": 1205 }, "evidence": [ { "id": "A0A8V0ZM16", "url": "https://omabrowser.org/oma/group/A0A8V0ZM16/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CSB4-1", "protein_name": "Partitioning defective 3 homolog B", "gene_name": "Pard3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILDPDDVLADVVEDKDKLIAVFDEQEPLQKTESPGGNPADRQSPDAFETEVAAQLAAFKPVGGEIVVTPSALKLGTPLLVRRSSDPAPGPHADAQPSTASLSGQSLKPVVLDSTQNVENKEAMNGEQAGLLSLHRPKDELSDMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFIRGIEENSRCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVILHVLLPQNREQYEKSVIGPLNIFGNNDGASRTKAAPPARGKPGLKAVHLTRASSPEGEEPASPQQSKSPRVPRLGRKPSSPSLSPLMGFGSKKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLVIARQEGSFLPRELKGEPDCYALSLESSEQLTLEIPLNDSGSAGLGVSLKGNKSRETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRPERPLEELSECGALSRPGFENCQEALSTSRRNDSSILYPFGTYSPQDKRKDLLLPSDGWAENEVPPSPPPHPALEWGLEDFSHSSGVDSTGYFPDQHVNFRTVTPVRQPELINLKASKSMDLVPDEGKVQSLADRRSDSPGKDFGPTLGLKKSSSLESLQTAVAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEADADGLSDKSSRSGHTALNCESAPQGNPELDNVENKAKNIKKTKEKEKKKGKGKLKVKEKKLKEEHEDAERKMKRKGFGAMLRFGKKKDDKVGKAEQKGAQKSGHPEEEELERMKEERERIGAKHQELREKQARGLVDYATAVTGPVHDMDDDEMDPNYARVNHFREPCASANVFRSPSPLRAGPLAYPRDGRPLSPDHLEGLYAKVNKPYHPPALADSGRPMAGTTDRIQKLRKEYYQARREGFLLYEDENTRARPSDHDLRWVSGKGPDGSTHNLRFEGMERQYASLPRGGSADPVDYLTASPRGRYNDRELPYYPGPHPVHAPRGSYPRPPDLRATDLRYPQYYPPPPAHQHKGPFRQDVPPSPPQHQRVPVYQEMGRAGPRGSSPDQYPYRNQDPRQKNPMTAAV", 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"pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 333, 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"class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLU9-1", "uniprot_ac": "A0A8V0ZLU9", "uniprot_id": "A0A8V0ZLU9_CHICK", "mass": { "chemical_mass": 50713.0, "monoisotopic_mass": 50713.0 }, "refseq": {}, "gene_names": [ { "name": "SLC17A9", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ] } ], "protein_names": [ { "name": "Voltage-gated purine nucleotide uniporter SLC17A9", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 17 member 9", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9/entry#names_and_taxonomy" } ] }, { "name": "Vesicular nucleotide transporter", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Voltage-gated ATP nucleotide uniporter that can also transport the purine nucleotides ADP and GTP. Uses the membrane potential as the driving force to control ATP accumulation in lysosomes and secretory vesicles. By controlling ATP storage in lysosomes, regulates ATP-dependent proteins of these organelles. Also indirectly regulates the exocytosis of ATP through its import into lysosomes in astrocytes and secretory vesicles such as adrenal chromaffin granules, mucin granules and synaptic vesicles.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZES0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES0#function" }, { "database": "UniProtKB", "id": "ARBA00056522", "url": "https://www.uniprot.org/uniprotkb/ARBA00056522#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC17A9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9", "locus": { "chromosome": "20", "start_pos": 8799509, "end_pos": 8784450, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021754", "url": "https://www.ensembl.org/id/ENSGALG00010021754" } ] } } ], "crossref": [ { "id": "A0A8V0ZLU9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17380", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17380", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419236", "url": "https://www.ncbi.nlm.nih.gov/gene/419236", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419236", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419236", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LITFWMP", "url": "https://omabrowser.org/oma/group/LITFWMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZES0", "url": "https://www.orthodb.org/?gene=A0A8V0ZES0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLU9", "url": "https://www.orthodb.org/?gene=A0A8V0ZLU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11662", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11662", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11662:SF279", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11662:SF279", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "75687", "url": "https://www.rhea-db.org/rhea/75687", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "75783", "url": "https://www.rhea-db.org/rhea/75783", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "75787", "url": "https://www.rhea-db.org/rhea/75787", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZES0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZES0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGGGRNAPVCGGERGSRAPQHDGMWKDGGGEQYWSRPECRAWTAVLLLGTCLLYCARVTVPICAVALSAHFGWDKKQSGVVLSSFFWGYCLTQVIGGHISDQIGGEKVLLLSASAWGFLTFITPLLTQITSAHLVFMTCSRFLMGLLQGVYFPSLASLLSQRVRESERAFTYSTVGTGSQFGTLVIGAAGSLLLDWYGWESVFYFSGLLTLLWVYCTCKYLLVEKDLVIPIGYLRRGISISKQSKVPWKQLFKKAPIWAVIVAQLCTASTFFTLLSWLPTFFKETFPESKGWVFNVVPWLVAIPTSLFSGFLSDHLINQGKSPSGFSSVIGSGVSSVFALCLGQTSSFCKAIVFASASVGLQTFNHSGISVNVQDLAPSCAGLLFGKALPAAHPMDRQDAAPLHFHLFPLCTGVVCVYLAGYLMETTGSWISVFNLVAVVNSVGLCVFLVFGEAQRVDTDSAYIDL", "length": 468, "header": "tr|A0A8V0ZLU9-1|A0A8V0ZLU9_CHICK Isoform 1 of Voltage-gated purine nucleotide uniporter SLC17A9 OS=Gallus gallus OX=9031 GN=SLC17A9 PE=3 SV=1 CANONICAL=A0A8V0ZLU9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZES0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9/entry#A0A8V0ZES0-1", "sequence": { "sequence": "MAAGGGRNAPVCGGERGSRAPQHDGMWKDGGGEQYWSRPECRAWTAVLLLGTCLLYCARVTVPICAVALSAHFGWDKKQSGVVLSSFFWGYCLTQVIGGHISDQIGGEKVLLLSASAWGFLTFITPLLTQITSAHLVFMTCSRFLMGLLQGVYFPSLASLLSQRVRESERAFTYSTVGTGSQFGTLVIGAAGSLLLDWYGWESVFYFSGLLTLLWVYCTCKYLLVEKDLVIPIGYLRRGISISKQSKVPWKQLFKKAPIWAVIVAQLCTASTFFTLLSWLPTFFKETFPESKGWVFNVVPWLVAIPTSLFSGFLSDHLINQGYKTITVRKFMQVIGSGVSSVFALCLGQTSSFCKAIVFASASVGLQTFNHSGISVNVQDLAPSCAGLLFGVGNTGGALLGVVCVYLAGYLMETTGSWISVFNLVAVVNSVGLCVFLVFGEAQRVDTDSAYIDL", "length": 454, "header": "tr|A0A8V0ZES0-1|A0A8V0ZLU9_CHICK Computationally mapped isoform of Voltage-gated purine nucleotide uniporter SLC17A9 OS=Gallus gallus OX=9031 GN=SLC17A9 PE=3 SV=1 CANONICAL=A0A8V0ZLU9-1" }, "locus": { "chromosome": "20", "start_pos": 8798083, "end_pos": 8784508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052887.1", "url": "https://www.ensembl.org/id/ENSGALT00010052887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031792.1", "url": "https://www.ensembl.org/id/ENSGALP00010031792.1" } ] } }, { "isoform_ac": "A0A8V0ZLU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9/entry#A0A8V0ZLU9-1", "sequence": { "sequence": "MAAGGGRNAPVCGGERGSRAPQHDGMWKDGGGEQYWSRPECRAWTAVLLLGTCLLYCARVTVPICAVALSAHFGWDKKQSGVVLSSFFWGYCLTQVIGGHISDQIGGEKVLLLSASAWGFLTFITPLLTQITSAHLVFMTCSRFLMGLLQGVYFPSLASLLSQRVRESERAFTYSTVGTGSQFGTLVIGAAGSLLLDWYGWESVFYFSGLLTLLWVYCTCKYLLVEKDLVIPIGYLRRGISISKQSKVPWKQLFKKAPIWAVIVAQLCTASTFFTLLSWLPTFFKETFPESKGWVFNVVPWLVAIPTSLFSGFLSDHLINQGKSPSGFSSVIGSGVSSVFALCLGQTSSFCKAIVFASASVGLQTFNHSGISVNVQDLAPSCAGLLFGKALPAAHPMDRQDAAPLHFHLFPLCTGVVCVYLAGYLMETTGSWISVFNLVAVVNSVGLCVFLVFGEAQRVDTDSAYIDL", "length": 468, "header": "tr|A0A8V0ZLU9-1|A0A8V0ZLU9_CHICK Isoform 1 of Voltage-gated purine nucleotide uniporter SLC17A9 OS=Gallus gallus OX=9031 GN=SLC17A9 PE=3 SV=1 CANONICAL=A0A8V0ZLU9-1" }, "locus": { "chromosome": "20", "start_pos": 8798083, "end_pos": 8784508, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052880.1", "url": "https://www.ensembl.org/id/ENSGALT00010052880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031786.1", "url": "https://www.ensembl.org/id/ENSGALP00010031786.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419236", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419236", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BR67-1", "protein_name": "Voltage-gated purine nucleotide uniporter SLC17A9", "gene_name": "SLC17A9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPPADEARRDGAEDAQWSRPEGQVWTGTLLLGTCLLYCARVSMPVCAAAMSQDFGWNKKEAGVVLSSFFWGYCLTQVVGGHLGDRIGGEKVILLSASAWGFITAATPLLAHLGSAHLAFMTFSRILTGLLQGVYFPALTSLLSQKVRESERAFTYSTVGAGSQFGTLVTGAVGSLLLDWYGWPSVFYFSGGLTLLWVWYVYKCLLSERDLILALGVLAQGLPVSRPTKVPWRQLFRKPAVWAAVTSQLSAACSFFILLCWLPTFFEETFPSSKGWVFNVVPWLVAIPASLLSGLLSDHLINQGYRTISVRKFMQVMGLGLSGVFALCLGHTSSFCTSVVFASASIGLQTFNHSGISVNIQDLAPSCAGFLFGVANTAGALAGVVGVCLGGYLIETTGSWASVFNLVAAVSSLGLCIFLVFGKAQRVDLSPAHEDL", "length": 436 }, "evidence": [ { "id": "A0A8V0ZLU9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLU9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MJF3-1", "protein_name": "Voltage-gated purine nucleotide uniporter SLC17A9", "gene_name": "Slc17a9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSQRSSLMHPTTEETRKTPFAAAEDTQWSRPECQAWTGMLLLGTCLLYCARVTMPVCTVAMSQDFGWNKKEAGIVLSSFFWGYCLTQVVGGHLGDRLGGEKVILLSASTWGFITVVTPLLVHLGSGHLAFMTFSRILMGLLQGVYFPALTSLLSQRVQESERAFTYSTVGAGSQFGTLVTGGVGSVLLDWCGWQSVFYFSGGLTLLWVYYVYRYLLNEKDLVLALGVLAQGLPMARPSKVPWRQLFRKPSVWAAVFSQLSSACSFFILLSWLPTFFKETFPYSKGWIFNVVPWLLAIPASLFSGFLSDRLISQGYRVIAVRKFMQVMGLGLSSIFALCLGHTTSFLKAMIFASASIGFQTFNHSGISVNIQDLAPSCAGFLFGVANTAGALAGVIGVCLSGYLIEATGSWTCIFNLVAIISNLGLGTFLVFGKAQRVDLAPTHEDL", "length": 447 }, "evidence": [ { "id": "A0A8V0ZLU9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLU9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P0DX21-1", "protein_name": "Voltage-gated purine nucleotide uniporter SLC17A9", "gene_name": "Slc17a9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSQRSSLMQPIPEETRKTPSAAAEDKRWSRPECQLWTGMLLLGTCLLYCTRVTMPVCTVAMSQDFGWNKKEAGIVLSSFFWGYCLTQVVGGHLGDRIGGEKVILLSASAWGFITVTTPLLAHLGSGHLAFVTFSRILTGLLQGVYFPALTSLLSQRVQESERSFTYSTVGAGSQVGTLVTGGIGSVLLDRCGWQSVFYFSGGLTLLWVYYVYKYLLDEKDLVLALGVLAQGLPVTRPSKVPWRQLFRKASVWAVICSQLSSACSFFILLSWLPTFFKETFPHSKGWVFNVVPWLLAIPASLFSGFISDRLISQGYRVITVRKFMQVMGLGLSSIFALCLGHTTSFLKSMIFASASIGFQTFNHSGISVNIQDLAPSCAGFLFGVANTAGALAGVVGVCLGGYLIETTGSWTCVFHLVAIVSNLGLGTFLVFGKAQRVDLVPTHEDL", "length": 447 }, "evidence": [ { "id": "A0A8V0ZLU9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLU9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54W37-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFDKTNSKENGLTNHAVSLNRYPTPKYYFPRRYLLVMIGFLGLCMAYILRVLISTTVIDMQAEYNYSNSFKGLLLSSFFMGYLSTQLLAQPLCDKIGGKKTLLFGLTLSIISSLFVPLAAQSKVAVVFVRIVTGITQGITYPTMNWLMSRWYPISERSSLASRTWTGAYIGTILVDFISPLILEYLGWEKAFYIFAGTALSWTLLWAIFIKDDPKDVIIGIHPNELAFINETEEKQPSEKSPLINKAQSYGSINQEVATGDSRSDYFASNGASMDEQESQLVKQNDIELPYFKVVKILLSSKALLTLLYFNLVTSWGFYLLLMWYPTWLLSVGVQTGIELSFFNALPYFISAVIASAMGVVADKLMARGVKKIIVRKVLGVLSAAIPGVFLFLIAFCKLSDKTQIAFMVIVVCSNGLAAAGPQMVTLDISPRYAGVTMGIGNFVATIPGILGPLIAGVLLEKFNSSWTQIFSMSATFYLSGAVIWAIFASSDKVL", "length": 495 }, "evidence": [ { "id": "A0A8V0ZLU9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLU9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VCL5-1", "protein_name": "Voltage-gated purine nucleotide uniporter SLC17A9", "gene_name": "Slc17a9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSQRSSLMQPIPEETRKTPSAAAEDTRWSRPECQAWTGILLLGTCLLYCARVTMPVCTVAMSQDFGWNKKEAGIVLSSFFWGYCLTQVVGGHLGDRIGGEKVILLSASAWGFITVTTPLLAHLGSGHLAFLTFSRILTGLLQGVYFPALTSLLSQKVQESERAFTYSTVGAGSQVGTLVTGGVGSVLLDQCGWQSVFYFSGGLTLLWAYYVYRYLLNEKDLVLALGFLAQGLPVTKPSKVPWRQLFRKASVWAAICSQLCSACSFFILLSWLPTFFKETFPNSKGWVFNVVPWMLAIPASLFSGFISDRLISQGYRVITVRKFMQVMGLGLSSIFALCLGHTTSFLKAMIFASASIGFQTFNHSGISVNIQDLAPSCAGFLFGVANTAGALAGVVGVCLSGYLIETTGSWTCVFHLVAIISNLGLGTFLVFGKAQRVDLVPTHEDL", "length": 447 }, "evidence": [ { "id": "A0A8V0ZLU9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLU9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BYT1-1", "protein_name": "Voltage-gated purine nucleotide uniporter SLC17A9", "gene_name": "SLC17A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPPPDEARRDMAGDTQWSRPECQAWTGTLLLGTCLLYCARSSMPICTVSMSQDFGWNKKEAGIVLSSFFWGYCLTQVVGGHLGDRIGGEKVILLSASAWGSITAVTPLLAHLSSAHLAFMTFSRILMGLLQGVYFPALTSLLSQKVRESERAFTYSIVGAGSQFGTLLTGAVGSLLLEWYGWQSIFYFSGGLTLLWVWYVYRYLLSEKDLILALGVLAQSRPVSRHNRVPWRRLFRKPAVWAAVVSQLSAACSFFILLSWLPTFFEETFPDAKGWIFNVVPWLVAIPASLFSGFLSDHLINQGYRAITVRKLMQGMGLGLSSVFALCLGHTSSFCESVVFASASIGLQTFNHSGISVNIQDLAPSCAGFLFGVANTAGALAGVVGVCLGGYLMETTGSWTCLFNLVAIISNLGLCTFLVFGQAQRVDLSSTHEDL", "length": 436 }, "evidence": [ { "id": "A0A8V0ZLU9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLU9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9FKV1-1", "protein_name": "Probable anion transporter 5", "gene_name": "ANTR5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKLSNIPQRYVIVFLTFLSTCVCYIERVGFSIAYTVAADAAGINQSSKGTILSTFFVGYACSQVPGGWAAQKIGGRKVLLLSFVLWSSTCFLVPLDPNRVGLLVVARLLVGVAQGFIFPSIHTVLAQWVPPHERSRLVSITTSGMYLGAALGMWLLPALVELRGPESVFLAEALAGVIWSLLWIRYATDPPRSEHPKAAAAGFGGALLPTNVNHHKVTHIPWKKIMLSLPVWAIVVNNFTFHYALYVLMNWLPTYFELGLQISLQGMDSSKMVPYLNMFVFSIVGGFIADYLITKRILSVTRTRKFLNTVGFLIASAALMVLPMFRTENGVILCSSVALGFLALGRAGFAVNHMDIAPRYAGIVMGVSNTAGTLAGIIGVDLTGKLLEASKLVYSDLSHPESWRVVFFIPGLLCIFSSVVFLLFSTGERIFD", "length": 432 }, "evidence": [ { "id": "A0A8V0ZLU9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLU9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VQZ7-1", "protein_name": "Major facilitator superfamily transporter 18", "gene_name": "MFS18", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDEKLKYSLLRGELVDTQSIWTRHEKRVWFITLITGTCMLYSTRTTMPLLVPAVASAQKWSKTDSGTVLSSFFWGYTLTQVVGGYFSDRFGGQRVILFAAIGWSLITFLMPTIIWTAGSIKSYAIPFIVAIRILNGALQGVHFPSMISLTSQNLCPNERSSFFGLLTAGSALGTLLTGIMGSFLLDYFGWSYVFRVIGLMGIAWALVLRYYAMAGERNRIINIATPSRLCANKSPAETSAVPWLRYFRRLSFWACVLTHACEMNCFFVLLSWLPTYFHDGFPHAKGWVVNMIPWLALPPCTLFAKYLTTRLLAREWHTTTVRKVIQSCCFAAQNLALFVMSRTSDFHTALICMTIIIGGTGFHNNAVTVNPQDLAPLHSGSVFGLMNTVGAIPGFLGVYLAGHILELTQSWPMVFSAAAGINLVGWIIFIVFGSAEAIV", "length": 439 }, "evidence": [ { "id": "A0A8V0ZLU9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLU9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "pmid": "" }, { "name": "chromaffin granule membrane", "id": "GO:0042584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042584", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "pmid": "" }, { "name": "mucin granule", "id": "GO:0098594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "pmid": "" }, { "name": "purine-containing compound transmembrane transport", "id": "GO:0072530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072530", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "pmid": "" }, { "name": "ATP transport", "id": "GO:0015867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "pmid": "" }, { "name": "purine nucleotide import into lysosome", "id": "GO:0141013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "purine nucleotide uniporter activity", "id": "GO:0160042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "pmid": "" }, { "name": "ATP transmembrane transporter activity", "id": "GO:0005347", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005347", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "pmid": "" }, { "name": "ADP transmembrane transporter activity", "id": "GO:0015217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015217", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "pmid": "" }, { "name": "guanine nucleotide transmembrane transporter activity", "id": "GO:0001409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001409", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "75687", "name": "", "equation": "ATP(in) = ATP(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "75687", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/75687" } ] }, { "id": "75783", "name": "", "equation": "ADP(in) = ADP(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "75783", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/75783" } ] }, { "id": "75787", "name": "", "equation": "GTP(in) = GTP(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "75787", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/75787" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU9" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 468, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 367, "end_pos": 369 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZM62-1", "uniprot_ac": "A0A8V0ZM62", "uniprot_id": "A0A8V0ZM62_CHICK", "mass": { "chemical_mass": 151326.0, "monoisotopic_mass": 151326.0 }, "refseq": { "ac": "XP_015149747", "name": "ubiquitin carboxyl-terminal hydrolase 42", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149747" }, "gene_names": [ { "name": "USP42", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62" } ] }, { "name": "USP42", "type": "synonym", "evidence": [ { "id": "XP_015149747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149747" } ] } ], "protein_names": [ { "name": "Ubiquitin specific peptidase 42", "type": "synonym", "evidence": [ { "id": "A0A8V0ZM62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 42", "type": "synonym", "evidence": [ { "id": "XP_015149747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149747" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149747" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USP42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62", "locus": { "chromosome": "14", "start_pos": 952368, "end_pos": 970977, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021756", "url": "https://www.ensembl.org/id/ENSGALG00010021756" } ] } } ], "crossref": [ { "id": "cd02661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416431", "url": "https://www.ncbi.nlm.nih.gov/gene/416431", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416431", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416431", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YGGRPYK", "url": "https://omabrowser.org/oma/group/YGGRPYK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZES5", "url": "https://www.orthodb.org/?gene=A0A8V0ZES5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM62", "url": "https://www.orthodb.org/?gene=A0A8V0ZM62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF727", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF727", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015149747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149747", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZES5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZES5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZES5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTIVKPKSSKSKKSSSRRSGKSKKPSAKNMKSRTANWGRIPPAKDPNQVSVNQGRGGAIYCRSSEKSKPFALRDLVINDGIAPPQRILFPPEKICMDWQQTQNVGVGLFNLGNTCFINSALQCLTYTPPLANYMLSLEHTQSCNYQGFCMMCTMETHINRVLCCAHDAIKPAFVVHELKRIGKHFRFGAQEDAHEFLRFTVDAMQQACLHGCTILDRSSQATTIIHQIFGGFLRSRVKCLNCKAVSDTYEAFLDIPLDIKTVSSVTKALEQFVKPEQLDGENCYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKINKEVKYPEYLDLRAYMSQSIGEPLIYALYAVLVHSGVNSHAGHYFCFIKAADGLWYQMNDASVVQSNIKTVLGQQAYLLFYIRRYDLTLGERAFYLPAPSYPRSFLGQRGTNSKQAGFMGPRLPPHMIKNSSRLNGNGSLKEDPNTVGVTLKRPSSAPPTACVQNWAITRPSITDPSKKQKITISIHNKLPARQTVSQPDCLRALEEEEELNKSVPSFTVTNSSAAESTSNASTMLFATNISEVPDEIFVEPVVNGNPKLSSDNMVSYGTESSGKPEDESSKGLFTRNCNIISSNGILIGKVCTLQNSYSSCQNAEEERSKHELPKNDSLNGANSLDNEPKENGLKLDDSSCQVPPVKPSEMLFPKTNGVLETMPIALSPDPQEIILDSFTYGQLNSLSEEISVPGPQKSSENDSLMETVVMEALLVYEESRKLPCDLSCEAGNLFIQSDSETISTKEVVAESIMTKADNAQLNINGQHKVRKRSLDTEDEFLENFESEDSDDKDKPRRSKEPDLISKENPLYIKGSPETEEELGQASSIKSDVECSSKKPACLDTADKCQDTKDISNNYVEVPPVNDSSITKLDKVLESQFSRENEGPTNRNCEENKHRKKDKHIYESKKTDKEHYRRKREHSDTEEREKQNSKPDGHSHKRRCSRSVETNKQNRRKQDYCNGNKYRSSYTERSSPDVSRNSGKYSHYRSRSRGREQGRNRYYHSKGERTWSRERYYQDEPWRWQKCRHYNDYYYSHAKGDSRERKFSHYNKDFDRSSQAYSRSHKDYHYKSRRPHHSLSREEDVRHFSSHRADSRHCSVPQQQSEKYSYERHILPPVLTHLRFEDSSPKNEKQSYRKRKYADSSESETERKSRKIEKEVLDDEKMKKYKKVKKKKKSKDKHREKDYKLYDSDFSVLHFDNDNRRRKKKKKKKKHIRKLKGFLEYLDPRFLKKTWEKEGSCSPADCLREQYRNEGSKQPDKEGKPSSCASEIENYISTASKEYIKDADY", "length": 1323, "header": "tr|A0A8V0ZM62-1|A0A8V0ZM62_CHICK Isoform 1 of Ubiquitin specific peptidase 42 OS=Gallus gallus OX=9031 GN=USP42 PE=4 SV=1 CANONICAL=A0A8V0ZM62-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZES5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62/entry#A0A8V0ZES5-1", "sequence": { "sequence": "MTIVKPKSSKSKKSSSRRSGKSKKPSAKNMKSRTANWGRIPPAKDPNQVSVNQGRGGAIYCRSSEKSKPFALRDLVINDGIAPPQRILFPPEKICMDWQQTQNVGVGLFNLGNTCFINSALQCLTYTPPLANYMLSLEHTQSCNYQGFCMMCTMETHINRVLCCAHDAIKPAFVVHELKRIGKHFRFGAQEDAHEFLRFTVDAMQQACLHGCTILDRSSQATTIIHQIFGGFLRSRVKCLNCKAVSDTYEAFLDIPLDIKTVSSVTKALEQFVKPEQLDGENCYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKINKEVKYPEYLDLRAYMSQSIGEPLIYALYAVLVHSGVNSHAGHYFCFIKAADGLWYQMNDASVVQSNIKTVLGQQAYLLFYIRRYDLTLGERAFYLPAPSYPRSFLGQRGTNSKQAGFMGPRLPPHMIKNSSRLNGNGSLKEDPNTVGVTLKRPSSAPPTACVQNWAITRPSITDPSKKQKITISIHNKLPARQTVSQPDCLRALEEEEELNKSVPSFTVTNSSAAESTSNASTMLFATNISEVPDEIFVEPVVNGNPKLSSDNMVSYGTESSGKPEDESSKGLFTRNCNIISSNGILIGKVCTLQNSYSSCQNAEEERSKHELPKNDSLNGANSLDNEPKENGLKLDDSSCQVPPVKPSEMLFPKTNGVLETMPIALSPDPQEIILDSFTYGQLNSLSEEISVPGPQKSSENDSLMETVVMEALLVYEESRKLPCDLSCEAGNLFIQSDSETISTKEVVAESIMTKADNAQLNINGQHKVRKRSLDTEDEFLENFESEDSDDKDKPRRSKEPDLISKENPLYIKGSPETEEELGQASSIKSDVECSSKKPACLDTADKCQDTKDISNNYVEVPPVNDSSITKLDKVLESQFSRENEGPTNRNCEENKHRKKDKHIYESKKTDKEHYRRKREHSDTEEREKQNSKPDGHSHKRRCSRSVETNKQNRRKQDYCNGNKYRSSYTERSSPDVSRNSGKYSHYRSRSRGREQGRNRYYHSKGERTWSRERYYQDEPWRWQKCRHYNDYYYSHAKGDSRERKFSHYNKDFDRSSQAYSRSHKDYHYKSRRPHHSLSREEDVRHFSSHRADSRHCSVPQQQSEKYSYERHILPPVLTHLRFEDSSPKNEKQSYRKRKYADSSESETERKSRKIEKEVLDDEKMKKYKKVKKKKKSKDKHREKDYKLYDSDFSVLHFDNDNRRRKKKKK", "length": 1245, "header": "tr|A0A8V0ZES5-1|A0A8V0ZM62_CHICK Computationally mapped isoform of Ubiquitin specific peptidase 42 OS=Gallus gallus OX=9031 GN=USP42 PE=4 SV=1 CANONICAL=A0A8V0ZM62-1" }, "locus": { "chromosome": "14", "start_pos": 967589, "end_pos": 956025, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052891.1", "url": "https://www.ensembl.org/id/ENSGALT00010052891.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031797.1", "url": "https://www.ensembl.org/id/ENSGALP00010031797.1" } ] } }, { "isoform_ac": "A0A8V0ZM62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62/entry#A0A8V0ZM62-1", "sequence": { "sequence": "MTIVKPKSSKSKKSSSRRSGKSKKPSAKNMKSRTANWGRIPPAKDPNQVSVNQGRGGAIYCRSSEKSKPFALRDLVINDGIAPPQRILFPPEKICMDWQQTQNVGVGLFNLGNTCFINSALQCLTYTPPLANYMLSLEHTQSCNYQGFCMMCTMETHINRVLCCAHDAIKPAFVVHELKRIGKHFRFGAQEDAHEFLRFTVDAMQQACLHGCTILDRSSQATTIIHQIFGGFLRSRVKCLNCKAVSDTYEAFLDIPLDIKTVSSVTKALEQFVKPEQLDGENCYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKINKEVKYPEYLDLRAYMSQSIGEPLIYALYAVLVHSGVNSHAGHYFCFIKAADGLWYQMNDASVVQSNIKTVLGQQAYLLFYIRRYDLTLGERAFYLPAPSYPRSFLGQRGTNSKQAGFMGPRLPPHMIKNSSRLNGNGSLKEDPNTVGVTLKRPSSAPPTACVQNWAITRPSITDPSKKQKITISIHNKLPARQTVSQPDCLRALEEEEELNKSVPSFTVTNSSAAESTSNASTMLFATNISEVPDEIFVEPVVNGNPKLSSDNMVSYGTESSGKPEDESSKGLFTRNCNIISSNGILIGKVCTLQNSYSSCQNAEEERSKHELPKNDSLNGANSLDNEPKENGLKLDDSSCQVPPVKPSEMLFPKTNGVLETMPIALSPDPQEIILDSFTYGQLNSLSEEISVPGPQKSSENDSLMETVVMEALLVYEESRKLPCDLSCEAGNLFIQSDSETISTKEVVAESIMTKADNAQLNINGQHKVRKRSLDTEDEFLENFESEDSDDKDKPRRSKEPDLISKENPLYIKGSPETEEELGQASSIKSDVECSSKKPACLDTADKCQDTKDISNNYVEVPPVNDSSITKLDKVLESQFSRENEGPTNRNCEENKHRKKDKHIYESKKTDKEHYRRKREHSDTEEREKQNSKPDGHSHKRRCSRSVETNKQNRRKQDYCNGNKYRSSYTERSSPDVSRNSGKYSHYRSRSRGREQGRNRYYHSKGERTWSRERYYQDEPWRWQKCRHYNDYYYSHAKGDSRERKFSHYNKDFDRSSQAYSRSHKDYHYKSRRPHHSLSREEDVRHFSSHRADSRHCSVPQQQSEKYSYERHILPPVLTHLRFEDSSPKNEKQSYRKRKYADSSESETERKSRKIEKEVLDDEKMKKYKKVKKKKKSKDKHREKDYKLYDSDFSVLHFDNDNRRRKKKKKKKKHIRKLKGFLEYLDPRFLKKTWEKEGSCSPADCLREQYRNEGSKQPDKEGKPSSCASEIENYISTASKEYIKDADY", "length": 1323, "header": "tr|A0A8V0ZM62-1|A0A8V0ZM62_CHICK Isoform 1 of Ubiquitin specific peptidase 42 OS=Gallus gallus OX=9031 GN=USP42 PE=4 SV=1 CANONICAL=A0A8V0ZM62-1" }, "locus": { "chromosome": "14", "start_pos": 967589, "end_pos": 953372, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052894.1", "url": "https://www.ensembl.org/id/ENSGALT00010052894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031800.1", "url": "https://www.ensembl.org/id/ENSGALP00010031800.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416431", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416431", "resource": "KEGG Pathway" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RQC2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42", "gene_name": "Usp42", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTIVDKTEPSDPSTCQNQPGSCEAVSPEDMDTGSASWGAVSSISDVSSHTLPLGPVPGAVVYSNSSVPEKSKPSPPKDQVLGDGIAPPQKVLFPSEKICLKWQQSHRVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCHAEGFCMMCTMQTHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYMSQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRAVLNQQAYVLFYIRSHDVKNGGESAHPAHSPGQSSPRPGVSQRVVNNKQVAPGFIGPQLPSHVMKNTPHLNGTTPVKDTPSSSVSSPNGNTSVNRASPATASTSVQNWSVTRPSVIPDHPKKQKITISIHNKLPARQGQAPLNNSLHGPCLEAPSKAAPSSTITNPSAIQSTSNVPTTSTSPSEACPKPMVNGKAKVGASVLVPYGAESSEESDEESKGLAKENGVDMMAGTHSDRPEAAADDGAEASSHELQEPVLLNGANSADSDSQENSLAFDSASCQVQPELHTENLFSKLNGLPGKVTPAPLQSVPEDRILETFKLTNQAKGPAGEESWTTTGGSSPKDPVSQLEPISDEPSPLEIPEAVTNGSTQTPSTTSPLEPTISCTKEDSSVVVSAEPVEGLPSVPALCNSTGTILGDTPVPELCDPGDLTANPSQPTEAVKGDTAEKAQDSAMAEVVERLSPAPSVLTGDGCEQKLLLYLSAEGSEETEDSSRSSAVSADTMPPKPDRTTTSSCEGAAEQAAGDRGDGGHVGPKAQEPSPAKEKMSSLRKVDRGHYRSRRERSSSGEHVRDSRPRPEDHHHKKRHCYSRERPKQDRHPTNSYCNGGQHLGHGDRASPERRSLSRYSHHHSRIRSGLEQDWSRYHHLENEHAWVRERFYQDKLRWDKCRYYHDRYTPLYTARDAREWRPLHGREHDRLVQSGRPYKDSYWGRKGWELQSRGKERPHFNSPREAPSLAVPLERHLQEKAALSVQDSSHSLPERFHEHKSVKSRKRRYETLENNDGRLEKKVHKSLEKDTLEEPRVKKHKKSKKKKKSKDKHRDRESRHQQESDFSGAYSDADLHRHRKKKKKKKRHSRKSEDFIKDVEMRLPKLSSYEAGGHFRRTEGSFLLADGLPVEDSGPFREKTKHLRMESRPDRCRLSEYGQGD", "length": 1324 }, "evidence": [ { "id": "A0A8V0ZM62", "url": "https://omabrowser.org/oma/group/A0A8V0ZM62/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZU96-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42", "gene_name": "Usp42", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTIVDKTEPSDPSTCQNQPGSSEAVSPEDMDTGSASWGAVSSISDVSNHTLSLGPVPGAVVYNNSSVPEKSKPSPPKDQVLGDGIAPPQKVLFPSEKICLKWQQSHRVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCHAEGFCMMCTMQTHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYMSQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLNQQAYVLFYIRSHDVKNGGETTHPAHSPGQSSPRPGISQRVVNSKQAAPGFIGPQLPPHVMKNTPHLNGTTPVKDTPSSSVSSPNGNTSVNRASPATASTSVQNWSVNRPSVIPEHPKKQKITISIHNKLPVRQGQAQLNNNLHGPCLEAPSKAAPSSTITNPSAIQSTSNAPTTSVSPSESCPKPMVNGKAKVGSSVLVPYGAESSEESDEESKGLAKENGVDMMTSTQSSRPETADEDGEASPHELQESVMLNGANSADSDSRESSLAFDSASCQVQPDLHTENLFNKLNGLPGKVTPAPLQSVPEDKILETFKLTNQAKGPAVEESWTTTGGSSPRASVSQPEPITDETSPLEIPEAVTNGSMKTPSTTSPLEPTISCTKEDSSVVVVSAEPMEVLPSVPALCNSTGTTLGDAPVPESCDPGDLTANPSQPSQAVKGDPAENSENSTLAEVVERLSPAPSVLTGDGCEQKLFLYLSTEGSEEAEDSSRSSAVSADTVPPQPDRTTSSCAGAAEQAAGDRGDGGSVGPKAQEPSPAKEKMNSLRKVDRGHYRSRRDRSSSGEHVRDSRARPEDHHHKKRRCYSRERPKQERHPANTYCNGGQHLGHGDRASPERRSLSRYSHHHSRVRSGLEQDWSRYHHSENEPAWARERFYPDKMRWDKCRYYHDRYTTTLYTAREAAREWRPLHGREHERLVQSGRPHKDSYWGRKGWDLQSRGKERPHFHSPREAPGLAVPLERHLQEKAALSVQDSSHSLPERFHEHESVKLRKRRYETLDNNDDHPEKKVHKSLEKDALEEPRAKKHKKSKKKKKSKDKHRARDSRHQQESDFSGAYSDADLHRHRKKKKKKKRHSRKSEDFIKDVEMHLPKLSSYEAVGHFRRTEGTFLLADGLPVEDSGPFREKTKHLRMESRPDRCHLSEYGQGN", "length": 1325 }, "evidence": [ { "id": "A0A8V0ZM62", "url": "https://omabrowser.org/oma/group/A0A8V0ZM62/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B9W9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42", "gene_name": "USP42", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTIVDKASESSDPSTYQNQPGSSEAVSPGDMDAGSASWGAVSSLNDVSNHTLSLGPVPGAVVYSSSSVPEKSKPSPQKDQALGDGIAPPQKVLFPSEKICLKWQQTHRVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCHAEGFCMMCTMQAHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYMSQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQAYVLFYIRSHDVKNGGELTHSAHSPGQSSPRPVISQRVVNSKQAASGFIGPQLPSHMMKNPPHLNGTGPLKETPSSPMSGPSGNSSVSRTGPVSASPSVQNWSVNRPSVIPEHPKKQKITISIHNKLPVRQGQSQSNLHSNSLEHPNKPAPSSTITTSSAIQSTSSAPTPPASSKVPKQMAPREACSRPMMNGRPRLSAGVLVPYGAESSEESDEEAKGLGQENGRGLTESACSPALDAEDGDASPHELQEPVALNGATGLDSDPTENGLPSDGAPCPGQPALHSEHPFPKANGLPGKLMPAPLPPLPEDKILETFKLGSKAKGSAEETRTPGSEERPLEHPEAELEAGRSPPGDARDNLESVSNLSSKFKKASPPSDPSIKPTKEEVSERVSAEPEEAVPSASTFCNPDKDALGDDQLLAPCDPGNLTDDQSKPSPDVGGTLPERPQDPVAAEAAGRLSPGPSVPSEGDHEPEPLGHSGRDRGSDAEGPSKSMGVSTDEAPSAQLDTITENRPEGPPERSSSERGEDSKAGQKAPEPCLVQEKVSSLRKVDRGHYRSRRDRSSSGEHARESRSRTEVQHRRKRPHREHERPRPERPRPEPCALAPQPPCPSSLARSGHHHSRSRGAPDQEWGRYHHAEGDHAWTREKYYPDRLRWERCRYHHDRSPLYPSREPRDWRPFHAEREYERAGPYGGRPYKDHYRGRKGYELVAKERDRHRFSSPRAGMAHAPPPHPAAKYTHDRLSFGAEDGSCDLAARFHEHDNIKSRKRRYDSLENESHVEKKAWRSLQKDPVEEPKVKKHKKSKKKKKSKDKHRDRDSRHQQDSDLSVAHSDADLHRHKKKKKKKKRHSRKSEDFGRDSEPRLPKAASCETVDHFRKAEGAFPLADGLPLEGAAPFCEKTKHFRMESREVRCRLSQCDQGKGARWESGS", "length": 1333 }, "evidence": [ { "id": "A0A8V0ZM62", "url": "https://omabrowser.org/oma/group/A0A8V0ZM62/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9H9J4-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42", "gene_name": "USP42", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTIVDKASESSDPSAYQNQPGSSEAVSPGDMDAGSASWGAVSSLNDVSNHTLSLGPVPGAVVYSSSSVPDKSKPSPQKDQALGDGIAPPQKVLFPSEKICLKWQQTHRVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCHAEGFCMMCTMQAHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYMSQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQAYVLFYIRSHDVKNGGELTHPTHSPGQSSPRPVISQRVVTNKQAAPGFIGPQLPSHMIKNPPHLNGTGPLKDTPSSSMSSPNGNSSVNRASPVNASASVQNWSVNRSSVIPEHPKKQKITISIHNKLPVRQCQSQPNLHSNSLENPTKPVPSSTITNSAVQSTSNASTMSVSSKVTKPIPRSESCSQPVMNGKSKLNSSVLVPYGAESSEDSDEESKGLGKENGIGTIVSSHSPGQDAEDEEATPHELQEPMTLNGANSADSDSDPKENGLAPDGASCQGQPALHSENPFAKANGLPGKLMPAPLLSLPEDKILETFRLSNKLKGSTDEMSAPGAERGPPEDRDAEPQPGSPAAESLEEPDAAAGLSSTKKAPPPRDPGTPATKEGAWEAMAVAPEEPPPSAGEDIVGDTAPPDLCDPGSLTGDASPLSQDAKGMIAEGPRDSALAEAPEGLSPAPPARSEEPCEQPLLVHPSGDHARDAQDPSQSLGAPEAAERPPAPVLDMAPAGHPEGDAEPSPGERVEDAAAPKAPGPSPAKEKIGSLRKVDRGHYRSRRERSSSGEPARESRSKTEGHRHRRRRTCPRERDRQDRHAPEHHPGHGDRLSPGERRSLGRCSHHHSRHRSGVELDWVRHHYTEGERGWGREKFYPDRPRWDRCRYYHDRYALYAARDWKPFHGGREHERAGLHERPHKDHNRGRRGCEPARERERHRPSSPRAGAPHALAPHPDRFSHDRTALVAGDNCNLSDRFHEHENGKSRKRRHDSVENSDSHVEKKARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDSRHQQDSDLSAACSDADLHRHKKKKKKKKRHSRKSEDFVKDSELHLPRVTSLETVAQFRRAQGGFPLSGGPPLEGVGPFREKTKHLRMESRDDRCRLFEYGQGKRRYLELGR", "length": 1324 }, "evidence": [ { "id": "A0A8V0ZM62", "url": "https://omabrowser.org/oma/group/A0A8V0ZM62/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 554, "end_pos": 556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 900, "end_pos": 902, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZM62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM62" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 106, "end_pos": 407, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 317, "end_pos": 319 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 545, "end_pos": 547 }, { "start_pos": 554, "end_pos": 556 }, { "start_pos": 563, "end_pos": 565 }, { "start_pos": 650, "end_pos": 652 }, { "start_pos": 736, "end_pos": 738 }, { "start_pos": 900, "end_pos": 902 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZL55-1", "uniprot_ac": "A0A8V0ZL55", "uniprot_id": "A0A8V0ZL55_CHICK", "mass": { "chemical_mass": 49469.0, "monoisotopic_mass": 49469.0 }, "refseq": {}, "gene_names": [ { "name": "ASCL3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZL55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55" } ] } ], "protein_names": [ { "name": "Chromosome 11 open reading frame 16", "type": "synonym", "evidence": [ { "id": "A0A8V0ZL55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASCL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZL55", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZL55", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19745", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19745", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107053378", "url": "https://www.ncbi.nlm.nih.gov/gene/107053378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107053378", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107053378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHAVNTD", "url": "https://omabrowser.org/oma/group/DHAVNTD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "MMDNRSY", "url": "https://omabrowser.org/oma/group/MMDNRSY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEU9", "url": "https://www.orthodb.org/?gene=A0A8V0ZEU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEW3", "url": "https://www.orthodb.org/?gene=A0A8V0ZEW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL55", "url": "https://www.orthodb.org/?gene=A0A8V0ZL55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL60", "url": "https://www.orthodb.org/?gene=A0A8V0ZL60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14343", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14343", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14343:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14343:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349:SF108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349:SF108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZEU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEW3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHAEGFLPMDHRYCSMMPALDKFPCSSAIPAIHPCCRSSFAVHPAWITKPLAPLRCQRFGCCLPSLGPAWQRLSTSQRSAILAKNVPVLVRGEHDGFYYRGTVKEEMENERGMFLVEFTRPLDLHGRHSVCVQKAAKDDILEYANGMKHSLLPGDKVLAPWEPDLVRYGPGTVLTGIETRDPLRASEDEEITVQFWNDKKVKLPRGVALWIHPSLCGRIVEMIHMPLSSRLKHRESLDTNSCIFSCSPKAAWVPVCVAHSHAKHSLLCSPCWPFLHCCGGGMCCSSACVRCFCCCRGHSDVFWPLPPKSQVFQRGAEEAELSSKSSPRLLELEGPKQGVLAAVAARSLSSDSEVFPTQSTAVDSTVDTDPSCPEKPRLEESAGPSGNTPEGTTASLVPVIQELADAAAYVQRASWNPKPSLLWTCPVLHHLIRLQCLKPQSSLPEGNSQ", "length": 450, "header": "tr|A0A8V0ZL55-1|A0A8V0ZL55_CHICK Isoform 1 of Chromosome 11 open reading frame 16 OS=Gallus gallus OX=9031 GN=ASCL3 PE=4 SV=1 CANONICAL=A0A8V0ZL55-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55/entry#A0A8V0ZEU9-1", "sequence": { "sequence": "MAHAEGFLPMDHRYCSMMPALDKFPCSSAIPAIHPCCRSSFAVHPAWITKPLAPLRCQRFGCCLPSLGPAWQRLSTSQRSAILAKNVPVLVRGEHDGFYYRGTVKEEMENERGMFLVEFTRPLDLHGRHSVCVQKAAKDDILEYANGMKHSLLPGDKVLAPWEPDLVRYGPGTVLTGIETRDPLRASEDEEITVQFWNDKKVKLPRGVALWIHPSLHAKHSLLCSPCWPFLHCCGGGMCCSSACVRCFCCCRGHSDVFWPLPPKSQVFQRGAEEAELSSKSSPRLLELEGPKQGVLAAVAARSLSSDSEVFPTQSTAVDSTVDTDPSCPEKPRRNHCKSRASNSAISVVDMSRVAPPDQTAVFETTEQPPGGQFTMNEMVKYRDFKLSSVVR", "length": 392, "header": "tr|A0A8V0ZEU9-1|A0A8V0ZL55_CHICK Computationally mapped isoform of Chromosome 11 open reading frame 16 OS=Gallus gallus OX=9031 GN=ASCL3 PE=4 SV=1 CANONICAL=A0A8V0ZL55-1" }, "locus": { "chromosome": "5", "start_pos": 9248066, "end_pos": 9244112, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049692.1", "url": "https://www.ensembl.org/id/ENSGALT00010049692.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029358.1", "url": "https://www.ensembl.org/id/ENSGALP00010029358.1" } ] } }, { "isoform_ac": "A0A8V0ZEW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55/entry#A0A8V0ZEW3-1", "sequence": { "sequence": "MDGKGCCNLMDKLSISADTQHIQLPRPFCADPLVMFHMYPETANQVACSEDLSFLPFMSEHFITENFCSDPCGFSYQIPHCSYNRSEYSYGPAFIRKRNERERQRVKCVNEGYAKLRHHLPKEYLEKRLSKVETLRAAIKYIRYLQSVLYSDSVAADKIVVEPSQAPKAINKQSQFLKAI", "length": 180, "header": "tr|A0A8V0ZEW3-1|A0A8V0ZL55_CHICK Computationally mapped isoform of Chromosome 11 open reading frame 16 OS=Gallus gallus OX=9031 GN=ASCL3 PE=4 SV=1 CANONICAL=A0A8V0ZL55-1" }, "locus": { "chromosome": "5", "start_pos": 9240990, "end_pos": 9240451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049683.1", "url": "https://www.ensembl.org/id/ENSGALT00010049683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029352.1", "url": "https://www.ensembl.org/id/ENSGALP00010029352.1" } ] } }, { "isoform_ac": "A0A8V0ZL55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55/entry#A0A8V0ZL55-1", "sequence": { "sequence": "MAHAEGFLPMDHRYCSMMPALDKFPCSSAIPAIHPCCRSSFAVHPAWITKPLAPLRCQRFGCCLPSLGPAWQRLSTSQRSAILAKNVPVLVRGEHDGFYYRGTVKEEMENERGMFLVEFTRPLDLHGRHSVCVQKAAKDDILEYANGMKHSLLPGDKVLAPWEPDLVRYGPGTVLTGIETRDPLRASEDEEITVQFWNDKKVKLPRGVALWIHPSLCGRIVEMIHMPLSSRLKHRESLDTNSCIFSCSPKAAWVPVCVAHSHAKHSLLCSPCWPFLHCCGGGMCCSSACVRCFCCCRGHSDVFWPLPPKSQVFQRGAEEAELSSKSSPRLLELEGPKQGVLAAVAARSLSSDSEVFPTQSTAVDSTVDTDPSCPEKPRLEESAGPSGNTPEGTTASLVPVIQELADAAAYVQRASWNPKPSLLWTCPVLHHLIRLQCLKPQSSLPEGNSQ", "length": 450, "header": "tr|A0A8V0ZL55-1|A0A8V0ZL55_CHICK Isoform 1 of Chromosome 11 open reading frame 16 OS=Gallus gallus OX=9031 GN=ASCL3 PE=4 SV=1 CANONICAL=A0A8V0ZL55-1" }, "locus": { "chromosome": "5", "start_pos": 9248016, "end_pos": 9244112, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049688.1", "url": "https://www.ensembl.org/id/ENSGALT00010049688.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029355.1", "url": "https://www.ensembl.org/id/ENSGALP00010029355.1" } ] } }, { "isoform_ac": "A0A8V0ZL60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55/entry#A0A8V0ZL60-1", "sequence": { "sequence": "MDGKGCCNLMDKLSISADTQHIQLPRPFCADPLVMFHMYPETANQVACSEDLSFLPFMSEHFITENFCSDPCGFSYQIPHCSYNRSEYSYGPAFIRKRNERERQRVKCVNEGYAKLRHHLPKEYLEKRLSKVETLRAAIKYISLAGSCLCKNGSCRRIPAHGPQVLQHDAGSGQVPLLQCHPCYPPLLQELLRRASCLDHQAPCSPAVKLSSCWVCDLFFCMISNRIKQAGMCQVNT", "length": 237, "header": "tr|A0A8V0ZL60-1|A0A8V0ZL60_CHICK Computationally mapped isoform of Chromosome 11 open reading frame 16 OS=Gallus gallus OX=9031 GN=ASCL3 PE=4 SV=1 CANONICAL=A0A8V0ZL55-1" }, "locus": { "chromosome": "5", "start_pos": 9244368, "end_pos": 9240451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049695.1", "url": "https://www.ensembl.org/id/ENSGALT00010049695.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029360.1", "url": "https://www.ensembl.org/id/ENSGALP00010029360.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107053378", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107053378", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZW49-1", "protein_name": "TMEM9 domain family, member B", "gene_name": "Tmem9b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLWCGSLLRLGSGLSMSCLALYVLLLAPLTGAAKNFEDVRCKCICPPYKENPGHIYNKNISQKDCDCLHVVEPMPVRGPDVEAYCLRCECKYEERSSVTIKVTIIIYLSILGLLLLYMVYLTLVEPILKRRLFGHSQLLQSDDDIGDHQPFANAHDVLARSRSRANVLNKVEYAQQRWKLQVQEQRKSVFDRHVVLS", "length": 199 }, "evidence": [ { "id": "A0A8V0ZL55", "url": "https://omabrowser.org/oma/group/A0A8V0ZL55/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6T9F7-1", "protein_name": "Similar to human chromosome 11 open reading frame 16", "gene_name": "C1h11orf16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPSTRPGLPLPKCCSVATTVKAPDLHGAVPPWDMSVACPFATQAAWLPTHCTVTRCGSCCPCFHTADPQWPGLSWLGRVGDAAGSWVLARKEQDGFYYLAQIKAAPELEKRGALVVEFEAPLVTDVKLPAQQRRVVFPEDVIQFSPSVPHSLQLGDKVLAPWEPEQQQYGPGTVLLGLKKQKGQRASKEKEIPVHFWNGKTAKVPLDRVRWVPPTVWKKAVERLQTPHTRDCHRSCLWAPHCSRLGPNTGCTAHRHPLDSSFLCPPCLSCACCQLQCQSSCPLVGPSWWPFTGTSELTTRELPEPEKPTAQLLSLQGPKEVAVFSHNMSSSSSSEEENSERHLEVGLPQRQMVSRAVNTDPILSETSLRQCSPHKPEWRYWRRNGPEPPPGKLGS", "length": 396 }, "evidence": [ { "id": "A0A8V0ZL55", "url": "https://omabrowser.org/oma/group/A0A8V0ZL55/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I3W9-1", "protein_name": "Achaete-scute homolog 3", "gene_name": "Ascl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDSRSYSSPPDRLSVFSESAHLPPSRPFYLDPMVTVHLCPETPVPSPYTEELPLLPFSSDTLIMDNYGDPYPFPFPMPYVNYRRCDYAYGPAFIRKRNERERQRVKCVNEGYARLRRHLPENYLEKRLSKVETLRAAIKYISYLQSLLYPDETEAERNPRTTSCGPLDPSFRVI", "length": 174 }, "evidence": [ { "id": "A0A8V0ZL55", "url": "https://omabrowser.org/oma/group/A0A8V0ZL55/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9JJR6-1", "protein_name": "Uncharacterized protein C11orf16 homolog", "gene_name": "D7h11orf16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPSASPGLPLPKYCSVATTVKAPDLHGAVPPWDMSFTCPFATQAPWLATHCTFTRCTACCPCLHTVDRPWPGLRWLGRVGAAGGSWVLARKEPDGFYYLAQIKAAPELEKRGALVVEFEAPLVTGLELPAQQQRVVFPEDVIQFSPSVPHSLQLGDKVLAPWEPGQQRYGPGTVLVGLKKQKGQRASKEKEITVHFWNGKTTKVPLGSVRWVPPTVWKKAVERLQAPHTRDCHSSCLWVPHCSQLGPRAGCTTHRHPLDSSFLCPPCLSCACCQLQCQSSCPLVGPSWWPLTRTSELTTRKLPEPEVKPTAQLLPLQGPKEEPVAELSYNMFSSSSSSSEEENSESHLEMGLPLRQMVSRAVNTDPILSETTSLQQYSPHKPEWRYWRRNGPEPPPGKPGR", "length": 402 }, "evidence": [ { "id": "A0A8V0ZL55", "url": "https://omabrowser.org/oma/group/A0A8V0ZL55/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJR7-1", "protein_name": "Achaete-scute homolog 3", "gene_name": "Ascl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTRSYPSPPDRLSVFAESAHLPLSRPFYLDPMVTVHLCPETPVPASYTDELPLLPFSSDTLIMNNYGDPYPFPFPMPYTNYRRCDYTYGPAFIRKRNERERQRVKCVNEGYARLRRHLPEDYLEKRLSKVETLRAAIKYISYLQSLLYPDESETKKNPRTASCGSLDPALRVI", "length": 174 }, "evidence": [ { "id": "A0A8V0ZL55", "url": "https://omabrowser.org/oma/group/A0A8V0ZL55/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQ32-1", "protein_name": "Uncharacterized protein C11orf16", "gene_name": "C11orf16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESSTGPRMPLLKYCSVATSLKAPGWDGAAPPWDLSFTYPFALQAPWLTGHKPLARHASSCPCLHVADPAWQGPGWLGRAGDAANTWVLARREADGFYYRAQIKATPELERQGVLLVEFEAPLVAGPKLPAQQQRVVLEEDVIPLSPSVGYSLRPGDKVLALWEPGQQQYGPGTVLLGLEMRDPQRASKEKEITVHFWNGKAAKVPLGGVQSVSLTIWKKAVERLHKSFTREHPRPLHWAPCCSLLGPITGRITNELPPDAPFLCPLCHHHACCQLLCQGCLCGCPPCGTTWWPLTRTSEVMARELPELEPTAQLLPLEGPKEEKVAMHAPLAVSSSSSSSCEQDGVENDLEMGPPQRLMVNSAVNTDPIFLEMPLRQSGLCQPEWRYWKRNGPEPCLGKPGTRYSNICKEEKDHKQQRAQTAVVGTTKELVSKATHMKPPRTPPGEAEHRKRSQSLAICQWNKNSR", "length": 467 }, "evidence": [ { "id": "A0A8V0ZL55", "url": "https://omabrowser.org/oma/group/A0A8V0ZL55/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9NQ33-1", "protein_name": "Achaete-scute homolog 3", "gene_name": "ASCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMDNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPSDSLILGNYSEPCPFSFPMPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHHLPEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFRIV", "length": 181 }, "evidence": [ { "id": "A0A8V0ZL55", "url": "https://omabrowser.org/oma/group/A0A8V0ZL55/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "epithelium development", "id": "GO:0060429", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060429", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZL55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL55" }, { "id": "PF15057", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4537", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 215, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKY2-1", "uniprot_ac": "A0A8V0ZKY2", "uniprot_id": "A0A8V0ZKY2_CHICK", "mass": { "chemical_mass": 81740.0, "monoisotopic_mass": 81740.0 }, "refseq": { "ac": "XP_421651", "name": "rho GTPase-activating protein 22 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421651" }, "gene_names": [ { "name": "ARHGAP22", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" } ] }, { "name": "ARHGAP22", "type": "synonym", "evidence": [ { "id": "XP_421651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421651" } ] } ], "protein_names": [ { "name": "Rho GTPase activating protein 22", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 22 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_421651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421651" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_421651.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421651" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGAP22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2", "locus": { "chromosome": "6", "start_pos": 19049923, "end_pos": 19184743, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020520", "url": "https://www.ensembl.org/id/ENSGALG00010020520" } ] } } ], "crossref": [ { "id": "A0A8V0ZKY2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04390", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04390", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13378", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423779", "url": "https://www.ncbi.nlm.nih.gov/gene/423779", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEX1", "url": "https://www.orthodb.org/?gene=A0A8V0ZEX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKY2", "url": "https://www.orthodb.org/?gene=A0A8V0ZKY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_421651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421651", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEPPLEEKPSCEEEACCSLSLKEQSFGTGEVVSGAVLQRARSKSLVMGEQIGPPSRPSSPNPQERVVKCGWLKKQRSIMKNWQQRWFVLRGDQLFYYKDEEETKPQGLILLQGNQVNELPPNPDEPGKHLFEIAPGGAGDREKMPVNHEAFLLMANSQNEMEDWVKAIRRVIWAPFGGGIFGQRLEDTVQYERKYGQRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVKDLQDSFDCGEKPLFDSNTDVHTVASLLKLYLRELPEPVIPFAKYEDFLSCGQLLSKDEGEGTQELVKQVKNLPQANYNLLKYICKFLDEVQAHSSVNKMSVQNLATVFGPNILRPKMEDPVTMMEGTSLVQHLMTVLISEQGRIFAVPQADVPGSQLEIRPVRPRNTVEWISEEDGEDSRSESNVPSPADLPSGNAVSLEATPGPVLKNTPPEHSSKLAQPATSPSKRVQTLPPWKYSFRQQGARSGSPKLGSSSLDIPNLSSSGNWLMNGLYSLRGHRRTASGERVKDSCSSQRLSTYDNVPSSSLSLSTHSMGSTTWSTSSCEISVVDSVSSCPACRASDSSALSSLQTEWMTQGSLSQSEVKTADLENSIDRLEACSSSSEQSNLAPASRDSVRCSRALQSLVVELKTELSKQRTEYETSIKRIEEASADLRKQVVRLEEELDQERKKYTMLEIKLRNSERAREDAEKRNHLLQKEMEEFFSTLGCLTGGSQSAKVPK", "length": 734, "header": "tr|A0A8V0ZKY2-1|A0A8V0ZKY2_CHICK Isoform 1 of Rho GTPase activating protein 22 OS=Gallus gallus OX=9031 GN=ARHGAP22 PE=4 SV=1 CANONICAL=A0A8V0ZKY2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2/entry#A0A8V0ZEX1-1", "sequence": { "sequence": "MLSPRIRQARRARSKSLVMGEQIGPPSRPSSPNPQERVVKCGWLKKQRSIMKNWQQRWFVLRGDQLFYYKDEEETKPQGLILLQGNQVNELPPNPDEPGKHLFEIAPGGAGDREKMPVNHEAFLLMANSQNEMEDWVKAIRRVIWAPFGGGIANSSHAHKLKHLPQGIFGQRLEDTVQYERKYGQRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVKDLQDSFDCGEKPLFDSNTDVHTVASLLKLYLRELPEPVIPFAKYEDFLSCGQLLSKDEGEGTQELVKQVKNLPQANYNLLKYICKFLDEVQAHSSVNKMSVQNLATVFGPNILRPKMEDPVTMMEGTSLVQHLMTVLISEQGRIFAVPQADVPGSQLEIRPVRPRNTVEWISEEDGEDSRSESNVPSPADLPSGNAVSLEATPGPVLKNTPPEHSSKLAQPATSPSKRVQTLPPWKYSFRQQGARSGSPKLGSSSLDIPNLSSSGNWLMNGLYSLRGHRRTASGERVKDSCSSQRLSTYDNVPSSSLSLSTHSMGSTTWSTSSCEISVVDSVSSCPACRASDSSALSSLQTEWMTQGSLSQSEVKTADLENSIDRLEACSSSSEQSNLAPASRDSVRCSRALQSLVVELKTELSKQRTEYETSIKRIEEASADLRKQVVRLEEELDQERKKYTMLEIKLRNSERAREDAEKRNHLLQKEMEEFFSTLGCLTGGSQSAKVPK", "length": 721, "header": "tr|A0A8V0ZEX1-1|A0A8V0ZKY2_CHICK Computationally mapped isoform of Rho GTPase activating protein 22 OS=Gallus gallus OX=9031 GN=ARHGAP22 PE=4 SV=1 CANONICAL=A0A8V0ZKY2-1" }, "locus": { "chromosome": "6", "start_pos": 19184606, "end_pos": 19050545, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049567.1", "url": "https://www.ensembl.org/id/ENSGALT00010049567.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029282.1", "url": "https://www.ensembl.org/id/ENSGALP00010029282.1" } ] } }, { "isoform_ac": "A0A8V0ZKY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2/entry#A0A8V0ZKY2-1", "sequence": { "sequence": "MEEPPLEEKPSCEEEACCSLSLKEQSFGTGEVVSGAVLQRARSKSLVMGEQIGPPSRPSSPNPQERVVKCGWLKKQRSIMKNWQQRWFVLRGDQLFYYKDEEETKPQGLILLQGNQVNELPPNPDEPGKHLFEIAPGGAGDREKMPVNHEAFLLMANSQNEMEDWVKAIRRVIWAPFGGGIFGQRLEDTVQYERKYGQRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVKDLQDSFDCGEKPLFDSNTDVHTVASLLKLYLRELPEPVIPFAKYEDFLSCGQLLSKDEGEGTQELVKQVKNLPQANYNLLKYICKFLDEVQAHSSVNKMSVQNLATVFGPNILRPKMEDPVTMMEGTSLVQHLMTVLISEQGRIFAVPQADVPGSQLEIRPVRPRNTVEWISEEDGEDSRSESNVPSPADLPSGNAVSLEATPGPVLKNTPPEHSSKLAQPATSPSKRVQTLPPWKYSFRQQGARSGSPKLGSSSLDIPNLSSSGNWLMNGLYSLRGHRRTASGERVKDSCSSQRLSTYDNVPSSSLSLSTHSMGSTTWSTSSCEISVVDSVSSCPACRASDSSALSSLQTEWMTQGSLSQSEVKTADLENSIDRLEACSSSSEQSNLAPASRDSVRCSRALQSLVVELKTELSKQRTEYETSIKRIEEASADLRKQVVRLEEELDQERKKYTMLEIKLRNSERAREDAEKRNHLLQKEMEEFFSTLGCLTGGSQSAKVPK", "length": 734, "header": "tr|A0A8V0ZKY2-1|A0A8V0ZKY2_CHICK Isoform 1 of Rho GTPase activating protein 22 OS=Gallus gallus OX=9031 GN=ARHGAP22 PE=4 SV=1 CANONICAL=A0A8V0ZKY2-1" }, "locus": { "chromosome": "6", "start_pos": 19179564, "end_pos": 19050545, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049564.1", "url": "https://www.ensembl.org/id/ENSGALT00010049564.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029280.1", "url": "https://www.ensembl.org/id/ENSGALP00010029280.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 435, "start_aa": "Thr", "end_pos": 435, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr435", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" } ], "pmid": "" }, { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 174, "start_aa": "Arg", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZKY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKY2" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZM14-1", "uniprot_ac": "A0A8V0ZM14", "uniprot_id": "A0A8V0ZM14_CHICK", "mass": { "chemical_mass": 54596.0, "monoisotopic_mass": 54596.0 }, "refseq": { "ac": "XP_004948637", "name": "F-box/LRR-repeat protein 20 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948637" }, "gene_names": [ { "name": "FBXL20", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" } ] }, { "name": "FBXL20", "type": "synonym", "evidence": [ { "id": "XP_004948637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948637" } ] } ], "protein_names": [ { "name": "F-box and leucine rich repeat protein 20", "type": "synonym", "evidence": [ { "id": "A0A8V0ZM14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14/entry#names_and_taxonomy" } ] }, { "name": "F-box/LRR-repeat protein 20 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004948637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948637" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004948637.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948637" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXL20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14", "locus": { "chromosome": "27", "start_pos": 4107625, "end_pos": 4128859, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021774", "url": "https://www.ensembl.org/id/ENSGALG00010021774" } ] } } ], "crossref": [ { "id": "A0A8V0ZM14", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZM14", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22115", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22115", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771869", "url": "https://www.ncbi.nlm.nih.gov/gene/771869", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771869", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771869", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LCNRIRY", "url": "https://omabrowser.org/oma/group/LCNRIRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZEX4", "url": "https://www.orthodb.org/?gene=A0A8V0ZEX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKE3", "url": "https://www.orthodb.org/?gene=A0A8V0ZKE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKF3", "url": "https://www.orthodb.org/?gene=A0A8V0ZKF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM14", "url": "https://www.orthodb.org/?gene=A0A8V0ZM14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMA5", "url": "https://www.orthodb.org/?gene=A0A8V0ZMA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMC1", "url": "https://www.orthodb.org/?gene=A0A8V0ZMC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSS7", "url": "https://www.orthodb.org/?gene=A0A8V0ZSS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13382", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13382", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13382:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13382:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004948637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948637", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZEX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRAAEPVPPGPSHTHGRWGEDISLSTCTHSTTTTTTIIIIIVAARAGREPSIAVLTHNWRPWKRDSSALNQMFSNNDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCQGVGDNALRTFAQNCRNIEVLNLNGCTKITDATCTSLSKFCSKLRHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGVQALVRGCGGLKALSLKGCTQLEDEALKYIGANCPELVTLNLQTCLQITDDGLITICRGCHKLQSLCASGCCNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHDLEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDRLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 494, "header": "tr|A0A8V0ZM14-1|A0A8V0ZM14_CHICK Isoform 1 of F-box and leucine rich repeat protein 20 OS=Gallus gallus OX=9031 GN=FBXL20 PE=4 SV=1 CANONICAL=A0A8V0ZM14-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZEX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14/entry#A0A8V0ZEX4-1", "sequence": { "sequence": "ANVRAVHRALGNAPIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCQGVGDNALRTFAQNCRNIEVLNLNGCTKITDATCTSLSKFCSKLRHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGVQALVRGCGGLKALSLKGCTQLEDEALKYIGANCPELVTLNLQTCLQITDDGLITICRGCHKLQSLCASGCCNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHDLEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDRLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 415, "header": "tr|A0A8V0ZEX4-1|A0A8V0ZM14_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 20 OS=Gallus gallus OX=9031 GN=FBXL20 PE=4 SV=1 CANONICAL=A0A8V0ZM14-1" }, "locus": { "chromosome": "27", "start_pos": 4120647, "end_pos": 4109727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052942.1", "url": "https://www.ensembl.org/id/ENSGALT00010052942.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031848.1", "url": "https://www.ensembl.org/id/ENSGALP00010031848.1" } ] } }, { "isoform_ac": "A0A8V0ZKE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14/entry#A0A8V0ZKE3-1", "sequence": { "sequence": "MRREMNGVTKSRFEMFSNNDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCQGVGDNALRTFAQNCRNIEVLNLNGCTKITDATCTSLSKFCSKLRHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGVQALVRGCGGLKALSLKGCTQLEDEALKYIGANCPELVTLNLQTCLQITDDGLITICRGCHKLQSLCASGCCNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHDLEKMDLEECVQITDSTLIQLSIHCPRLQVLSPGYDVQGHRDFTKLVSLIAESLSHCELITDDGIRHLGNGACAHDRLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 457, "header": "tr|A0A8V0ZKE3-1|A0A8V0ZKE3_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 20 OS=Gallus gallus OX=9031 GN=FBXL20 PE=4 SV=1 CANONICAL=A0A8V0ZM14-1" }, "locus": { "chromosome": "27", "start_pos": 4128580, "end_pos": 4109727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052955.1", "url": "https://www.ensembl.org/id/ENSGALT00010052955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031861.1", "url": "https://www.ensembl.org/id/ENSGALP00010031861.1" } ] } }, { "isoform_ac": "A0A8V0ZKF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14/entry#A0A8V0ZKF3-1", "sequence": { "sequence": "STRSFPKSCCCEFSLSWTWSLCVAALRSPGAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCQGVGDNALRTFAQNCRNIEVLNLNGCTKITDATCTSLSKFCSKLRHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGVQALVRGCGGLKALSLKGCTQLEDEALKYIGANCPELVTLNLQTCLQITDDGLITICRGCHKLQSLCASGCCNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHDLEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDRLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 413, "header": "tr|A0A8V0ZKF3-1|A0A8V0ZKF3_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 20 OS=Gallus gallus OX=9031 GN=FBXL20 PE=4 SV=1 CANONICAL=A0A8V0ZM14-1" }, "locus": { "chromosome": "27", "start_pos": 4122367, "end_pos": 4109727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052965.1", "url": "https://www.ensembl.org/id/ENSGALT00010052965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031871.1", "url": "https://www.ensembl.org/id/ENSGALP00010031871.1" } ] } }, { "isoform_ac": "A0A8V0ZM14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14/entry#A0A8V0ZM14-1", "sequence": { "sequence": "MRRAAEPVPPGPSHTHGRWGEDISLSTCTHSTTTTTTIIIIIVAARAGREPSIAVLTHNWRPWKRDSSALNQMFSNNDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCQGVGDNALRTFAQNCRNIEVLNLNGCTKITDATCTSLSKFCSKLRHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGVQALVRGCGGLKALSLKGCTQLEDEALKYIGANCPELVTLNLQTCLQITDDGLITICRGCHKLQSLCASGCCNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHDLEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDRLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 494, "header": "tr|A0A8V0ZM14-1|A0A8V0ZM14_CHICK Isoform 1 of F-box and leucine rich repeat protein 20 OS=Gallus gallus OX=9031 GN=FBXL20 PE=4 SV=1 CANONICAL=A0A8V0ZM14-1" }, "locus": { "chromosome": "27", "start_pos": 4125229, "end_pos": 4109727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052947.1", "url": "https://www.ensembl.org/id/ENSGALT00010052947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031853.1", "url": "https://www.ensembl.org/id/ENSGALP00010031853.1" } ] } }, { "isoform_ac": "A0A8V0ZMA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14/entry#A0A8V0ZMA5-1", "sequence": { "sequence": "MEKVIFMKVQKLSPVIGLAAVPMDLGIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCQGVGDNALRTFAQNCRNIEVLNLNGCTKITDATCTSLSKFCSKLRHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGVQALVRGCGGLKALSLKGCTQLEDEALKYIGANCPELVTLNLQTCLQITDDGLITICRGCHKLQSLCASGCCNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHDLEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDRLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 427, "header": "tr|A0A8V0ZMA5-1|A0A8V0ZMA5_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 20 OS=Gallus gallus OX=9031 GN=FBXL20 PE=4 SV=1 CANONICAL=A0A8V0ZM14-1" }, "locus": { "chromosome": "27", "start_pos": 4120242, "end_pos": 4109727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052935.1", "url": "https://www.ensembl.org/id/ENSGALT00010052935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031841.1", "url": "https://www.ensembl.org/id/ENSGALP00010031841.1" } ] } }, { "isoform_ac": "A0A8V0ZMC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14/entry#A0A8V0ZMC1-1", "sequence": { "sequence": "MRMFSNNDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCQGVGDNALRTFAQNCRNIEVLNLNGCTKITDATCTSLSKFCSKLRHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGVQALVRGCGGLKALSLKGCTQLEDEALKYIGANCPELVTLNLQTCLQITDDGLITICRGCHKLQSLCASGCCNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHDLEKMDLEECVQITDSTLIQLSIHCPRLQVLFVPLRADHGRWHSPPGERRLRPRPPGGDRVGQLPPDHRRFPGAPEELPQPGEDRAVRLPADHAGGDQETQDPFTQHQSPRLLRAGDTTSIGRGQPTALLQMLHHPMTLEAAIPAN", "length": 433, "header": "tr|A0A8V0ZMC1-1|A0A8V0ZMC1_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 20 OS=Gallus gallus OX=9031 GN=FBXL20 PE=4 SV=1 CANONICAL=A0A8V0ZM14-1" }, "locus": { "chromosome": "27", "start_pos": 4126999, "end_pos": 4109698, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052951.1", "url": "https://www.ensembl.org/id/ENSGALT00010052951.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031857.1", "url": "https://www.ensembl.org/id/ENSGALP00010031857.1" } ] } }, { "isoform_ac": "A0A8V0ZSS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14/entry#A0A8V0ZSS7-1", "sequence": { "sequence": "MGAAALCGMFSNNDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCQGVGDNALRTFAQNCRNIEVLNLNGCTKITDATCTSLSKFCSKLRHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGVQALVRGCGGLKALSLKGCTQLEDEALKYIGANCPELVTLNLQTCLQITDDGLITICRGCHKLQSLCASGCCNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHDLEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDRLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 430, "header": "tr|A0A8V0ZSS7-1|A0A8V0ZM14_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 20 OS=Gallus gallus OX=9031 GN=FBXL20 PE=4 SV=1 CANONICAL=A0A8V0ZM14-1" }, "locus": { "chromosome": "27", "start_pos": 4128835, "end_pos": 4109727, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052960.1", "url": "https://www.ensembl.org/id/ENSGALT00010052960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031865.1", "url": "https://www.ensembl.org/id/ENSGALP00010031865.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 475, "start_aa": "Thr", "end_pos": 475, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr475", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:771869", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771869", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QU00-1", "protein_name": "F-box/LRR-repeat protein 20", "gene_name": "FBXL20", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVRVQSLAREFLHEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 436 }, "evidence": [ { "id": "A0A8V0ZM14", "url": "https://omabrowser.org/oma/group/A0A8V0ZM14/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A8DYA6-1", "protein_name": "F-box domain-containing protein", "gene_name": "Dmel\\CG9003", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFASSAETGVMEVGGTSGTGTGSSSSNNGGGSSSNSGGAGGSIELLCPPSGSSSISGSASFSSNSGASGSSSQTHSTAVSSATDRSNNNGNNHNPSLQLNGNGGSNTRQHSSGSNSRQHSSSSSNSNSSNISPPPSSSSSSRSNNNNNNHSSNIISGFCSTIWRSATFGSATPVINPLPAVSINPKIMESSSDSCSLSSSTTPDVGLADQQRNMAGSAQDQSEDQSQTFLGATELDDELIKQLPKEVLLRVFSYLDVVSLCRCAQVCKYWNVLALDGSSWQKINLFDFQRDIEGPVIENISQRCRGFLKSLSLRGCQSVGDQSVRTLANHCHNIEHLDLSDCKKITDISTQSISRYCSKLTAINLHSCSNITDNSLKYLSDGCPNLMEINVSWCHLISENGVEALARGCVKLRKFSSKGCKQINDNAIMCLAKYCPDLMVLNLHSCETITDSSIRQLAANCHKLQKLCVSKCADLTDLTLLSLSQHNHLLNTLEVSGCRNFTDIGFQALGRNCKYLERMDLEECSQITDLTLAHLATGCPSLEKLTLSHCELITDDGIRHLTTGSCAAEILSVLELDNCPLITDRTLEHLVSCHNLQRIELFDCQLITRTAIRKLKNHLPNIKVHAYFAPGTPPAVTSGHRPRYCRCCEIL", "length": 651 }, "evidence": [ { "id": "A0A8V0ZM14", "url": "https://omabrowser.org/oma/group/A0A8V0ZM14/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "B8K0E7-1", "protein_name": "F-box/LRR-repeat protein 20", "gene_name": "fbxl20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKEVNGVSRSRFEMFSNNDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRSWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDSALRTFAQNCRNIELLSLNGCTKITDSTCNSLSKFCPKLKHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRCCPGLKGLFLKGCTQLEDEALKHIGGHCPELVTLNLQTCSQITDEGLITICRGCHRLQSLCVSGCANITDAILNALGQNCPRLRILEVARCSQLTDVGFTSLARNCHELEKMDLEECVQITDATLIQLSIHCPRLQVLSLSHCELITDDGIRQLGSGPCAHDRLEVIELDNCPLITDASLEHLKSCHSLDRIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCVLL", "length": 436 }, "evidence": [ { "id": "A0A8V0ZM14", "url": "https://omabrowser.org/oma/group/A0A8V0ZM14/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q58DG6-1", "protein_name": "F-box/LRR-repeat protein 20", "gene_name": "FBXL20", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 436 }, "evidence": [ { "id": "A0A8V0ZM14", "url": "https://omabrowser.org/oma/group/A0A8V0ZM14/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96IG2-1", "protein_name": "F-box/LRR-repeat protein 20", "gene_name": "FBXL20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 436 }, "evidence": [ { "id": "A0A8V0ZM14", "url": "https://omabrowser.org/oma/group/A0A8V0ZM14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle exocytosis", "id": "GO:2000300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000300", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" } ], "pmid": "" }, { "name": "regulation of protein catabolic process at presynapse, modulating synaptic transmission", "id": "GO:0099575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZM14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM14" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 126, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 475 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 317, "end_pos": 319 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZL71-1", "uniprot_ac": "A0A8V0ZL71", "uniprot_id": "A0A8V0ZL71_CHICK", "mass": { "chemical_mass": 32197.0, "monoisotopic_mass": 32197.0 }, "refseq": { "ac": "NP_001006304", "name": "lysosomal amino acid transporter 1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006304" }, "gene_names": [ { "name": "PQLC2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZL71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71" } ] }, { "name": "PQLC2", "type": "synonym", "evidence": [ { "id": "NP_001006304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006304" } ] }, { "name": "SLC66A1", "type": "synonym", "evidence": [ { "id": "NP_001006304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006304" } ] } ], "protein_names": [ { "name": "Lysosomal amino acid transporter 1 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0ZL71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71/entry#names_and_taxonomy" } ] }, { "name": "PQ-loop repeat-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001006304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006304" }, { "id": "A0A8V0ZL71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 66 member 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZL71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71/entry#names_and_taxonomy" } ] }, { "name": "lysosomal amino acid transporter 1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001006304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006304" } ] }, { "name": "solute carrier family 66 member 1", "type": "synonym", "evidence": [ { "id": "NP_001006304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006304" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720314.1, SRR13267649.3097.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000329.1. On Sep 23, 2021 this sequence version replaced NP_001006304.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006304", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006304" } ] }, { "annotation": "Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71#function" }, { "database": "UniProtKB", "id": "ARBA00056009", "url": "https://www.uniprot.org/uniprotkb/ARBA00056009#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PQLC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71", "locus": { "chromosome": "21", "start_pos": 4675179, "end_pos": 4670631, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020594", "url": "https://www.ensembl.org/id/ENSGALG00010020594" } ] } } ], "crossref": [ { "id": "A0A8V0ZL71", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZL71", "database": "AlphaFoldDB", "categories": [] }, { "id": "419472", "url": "https://www.ncbi.nlm.nih.gov/gene/419472", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419472", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419472", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMCIFIQ", "url": "https://omabrowser.org/oma/group/DMCIFIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF44", "url": "https://www.orthodb.org/?gene=A0A8V0ZF44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL71", "url": "https://www.orthodb.org/?gene=A0A8V0ZL71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16201", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16201", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16201:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16201:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5223345", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5223345", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006304", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006304", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEGLRAPPPPGNGSECPDGARWVLRLLGECARDGRDVSSALLGLLSIGCFAAAALPQFYQACKTGIMDRALSIYFLLGWLGGDLLNLIGSFLANQLPLQVYTAVYYVLADLVMLSLYGYYKAKNWGTGATASINAACLFCLLGTATTLTVLSHDTGPAPNPAAFGGRSLLSLGLEGPGPEPISKTEIIGFAIGSISSVLYLCSRLPQIYTNYRRKSTAGVSFLLFALVMLGNLLYGTSVLLKNPEPGQSEGDYILHHLPWLIGSLGVLSLDVIISFQFLAYRTGQPSAGEEREALLAEHGDS", "length": 303, "header": "tr|A0A8V0ZL71-1|A0A8V0ZL71_CHICK Isoform 1 of Lysosomal amino acid transporter 1 homolog OS=Gallus gallus OX=9031 GN=PQLC2 PE=3 SV=1 CANONICAL=A0A8V0ZL71-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZF44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71/entry#A0A8V0ZF44-1", "sequence": { "sequence": "MAEGLRAPPPPGNGSECPDGARWVLRLLGECARDGRDVSSALLGLLSIGCFAAAALPQFYQACKTGIMDRALSIYFLLGWLGGDLLNLIGSFLANQLPLQVYTAVYYVLADLVMLSLYGYYKAKNWGTGATASINAACLFCLLGTATTLTVLSHDTGPAPNPAAFGGRSLLSLGLEGPGPEPISKTEIIGFAIGSISSVLYLCSRLPQIYTNVSEGSRHAKSRSEQGSGFLPSSLLGGCSSLTSHCVTACSEARFVFLPLQLNNVSVELSFFFPHLQAKREPNGTRQSVPIFSFPTAE", "length": 298, "header": "tr|A0A8V0ZF44-1|A0A8V0ZL71_CHICK Computationally mapped isoform of Lysosomal amino acid transporter 1 homolog OS=Gallus gallus OX=9031 GN=PQLC2 PE=3 SV=1 CANONICAL=A0A8V0ZL71-1" }, "locus": { "chromosome": "21", "start_pos": 4673702, "end_pos": 4671058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049698.1", "url": "https://www.ensembl.org/id/ENSGALT00010049698.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029362.1", "url": "https://www.ensembl.org/id/ENSGALP00010029362.1" } ] } }, { "isoform_ac": "A0A8V0ZL71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71/entry#A0A8V0ZL71-1", "sequence": { "sequence": "MAEGLRAPPPPGNGSECPDGARWVLRLLGECARDGRDVSSALLGLLSIGCFAAAALPQFYQACKTGIMDRALSIYFLLGWLGGDLLNLIGSFLANQLPLQVYTAVYYVLADLVMLSLYGYYKAKNWGTGATASINAACLFCLLGTATTLTVLSHDTGPAPNPAAFGGRSLLSLGLEGPGPEPISKTEIIGFAIGSISSVLYLCSRLPQIYTNYRRKSTAGVSFLLFALVMLGNLLYGTSVLLKNPEPGQSEGDYILHHLPWLIGSLGVLSLDVIISFQFLAYRTGQPSAGEEREALLAEHGDS", "length": 303, "header": "tr|A0A8V0ZL71-1|A0A8V0ZL71_CHICK Isoform 1 of Lysosomal amino acid transporter 1 homolog OS=Gallus gallus OX=9031 GN=PQLC2 PE=3 SV=1 CANONICAL=A0A8V0ZL71-1" }, "locus": { "chromosome": "21", "start_pos": 4674252, "end_pos": 4671058, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049707.1", "url": "https://www.ensembl.org/id/ENSGALT00010049707.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029370.1", "url": "https://www.ensembl.org/id/ENSGALP00010029370.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419472", "resource": "KEGG Pathway" }, { "id": "R-GGA-5223345", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5223345", "resource": "Reactome", "description": "Miscellaneous transport and binding events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7UY59-1", "protein_name": "Lysosomal amino acid transporter 1 homolog", "gene_name": "slc66a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDGFELGGGGNFSSLCPNGIAWIWYGLGECAQDGRDVASVVLGLLSIVCFMVSSIPQYYSSCKTGNMDSALSIWFLLFWLAGDSCNLIGSFLADQLPLQKYTAVYYVVADLLMLAMYMYYKLKNKRSSDRALLNALSVLCLLGMTSSLLSIPHWSLEDQMPSGFRGRALLALEEDNGAVQPFKTREIIGFVIGSISSVLYLCSRLPQIYTNFQRKSTEGLSYFLFALVILGNTTYGVSVLLKNPDPGQGEASYMVHHLPWLIGSLGTLSLDLVISVQFMMYRKSPQVSADTDEERAALLQN", "length": 302 }, "evidence": [ { "id": "A0A8V0ZL71", "url": "https://omabrowser.org/oma/group/A0A8V0ZL71/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B0BMY1-1", "protein_name": "Lysosomal amino acid transporter 1 homolog", "gene_name": "Slc66a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVWRTLVASNFSTCPNGSIQWIWDVFGECAQDGWDEASVALGLVSIFCFAASTFPQYIKACKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLLMLTLYFHYKFKKQPSLLSAPINSVLLFILGTVCITPLLSSTDPVAVPREGFRGRTLLSVEPGNKPFTKKEVVGFVIGSASSVLYLLSRLPQIRTNFVRQSTQGISYSLFALVMLGNTLYGLSVLLKNPEVGQSEGSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRSHDADAASEREPLLPS", "length": 293 }, "evidence": [ { "id": "A0A8V0ZL71", "url": "https://omabrowser.org/oma/group/A0A8V0ZL71/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HU25-1", "protein_name": "Lysosomal amino acid transporter 1 homolog", "gene_name": "Slc66a1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVWRTLGASNFSMCPNGSIQWIWDVFGECAQDGWDEASVVLGLVSILCFAASTFPQYIKACKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLMMLTLYFHYKFKNRSSPLSAPINSVLLFILGTVCITPLLRVADPVAVSREGFRGRTLLSVEPGNKPFTKKEVIGFVIGSVSSVLYLLSRLPQIRTNFLRQSTQGISYSLFALVMLGNTLYGLSVLLKNPEVGQSEGSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRSQATAAASETEPLLPS", "length": 293 }, "evidence": [ { "id": "A0A8V0ZL71", "url": "https://omabrowser.org/oma/group/A0A8V0ZL71/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6ZP29-1", "protein_name": "Lysosomal amino acid transporter 1 homolog", "gene_name": "SLC66A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVWKKLGSRNFSSCPSGSIQWIWDVLGECAQDGWDEASVGLGLISILCFAASTFPQFIKAYKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLVMLTLYFYYKFRTRPSLLSAPINSVLLFLMGMACATPLLSAAGPVAAPREAFRGRALLSVESGSKPFTRQEVIGFVIGSISSVLYLLSRLPQIRTNFLRKSTQGISYSLFALVMLGNTLYGLSVLLKNPEEGQSEGSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRRSTAASELEPLLPS", "length": 291 }, "evidence": [ { "id": "A0A8V0ZL71", "url": "https://omabrowser.org/oma/group/A0A8V0ZL71/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C4N4-1", "protein_name": "Lysosomal amino acid transporter 1 homolog", "gene_name": "Slc66a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVWRTLGASNFSTCPNGSVQWIWDVFGECAQDGWDEASVGLGLVSILCFAASTFPQYIKACKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLMMLTLYFHYKFKKRPSPLSAPINSVLLFILGTVCITPLLSSTDPVAVPREGFRGRTLLSVEPGNKPFTKKEVIGFVIGSASSLLYLLSRLPQIRTNFIRQSTQGISYSLFALVMLGNTLYGLSVLLKNPEVGQSEGSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRSHETAAASEREPLLPS", "length": 293 }, "evidence": [ { "id": "A0A8V0ZL71", "url": "https://omabrowser.org/oma/group/A0A8V0ZL71/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "basic amino acid transmembrane transporter activity", "id": "GO:0015174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015174", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71" } ], "pmid": "" }, { "name": "L-lysine transmembrane transporter activity", "id": "GO:0015189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015189", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71" } ], "pmid": "" }, { "name": "L-histidine transmembrane transporter activity", "id": "GO:0005290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005290", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71" } ], "pmid": "" }, { "name": "L-arginine transmembrane transporter activity", "id": "GO:0061459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lytic vacuole membrane", "id": "GO:0098852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lysine transport", "id": "GO:0015819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71" } ], "pmid": "" }, { "name": "intracellular amino acid homeostasis", "id": "GO:0080144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080144", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL71" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLD9-1", "uniprot_ac": "A0A8V0ZLD9", "uniprot_id": "A0A8V0ZLD9_CHICK", "mass": { "chemical_mass": 39200.0, "monoisotopic_mass": 39200.0 }, "refseq": {}, "gene_names": [ { "name": "ANKRD2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ANKRD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9", "locus": { "chromosome": "6", "start_pos": 23111835, "end_pos": 23114085, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020642", "url": "https://www.ensembl.org/id/ENSGALG00010020642" } ] } } ], "crossref": [ { "id": "A0A8V0ZLD9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF46", "url": "https://www.orthodb.org/?gene=A0A8V0ZF46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLD9", "url": "https://www.orthodb.org/?gene=A0A8V0ZLD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLE6", "url": "https://www.orthodb.org/?gene=A0A8V0ZLE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24126", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24126", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24126:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24126:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZF46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPQRLKGDGPREPLAVERMSTPELEEEKRQGPRNRGIEAIKVRALCRGVGCRRAPSWGPTECCMSPQGQDRVRRSSVDLRREIIDVGSIQRLIELRKQRRKRREERAATPEPTPPPEPEEIEGPVEPEDFLRAAVQGKIRVIEKFLADGGPPDTCDEFHRTALHRSSLEGHMDILQKLLDSGATVDFRDRLDSAAVHWACRGGHLDAVKLLQDRGADLNLKDKLLSTPLHVATRTGHLDIVEHLIHCGVDINSPDRVSATPTCSPSPCSLGDAVHRARLLLLQEGDTALHDATRLSRYKIIKVLILHGADMMARNLAGKTPTDLVQQWQVDTRQALETKERPQEETEVPA", "length": 351, "header": "tr|A0A8V0ZLD9-1|A0A8V0ZLD9_CHICK Isoform 1 of Ankyrin repeat domain 2 OS=Gallus gallus OX=9031 GN=ANKRD2 PE=4 SV=1 CANONICAL=A0A8V0ZLD9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZF46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9/entry#A0A8V0ZF46-1", "sequence": { "sequence": "MELDGEKGKELEVEQITELDVEKAKELIDQKLAEEEEEEKRLKGDGPREPLAVERMSTPELEEEKRQGPRNRGIEAIKGQDRVRRSSVDLRREIIDVGSIQRLIELRKQRRKRREERAATPEPTPPPEPEEIEGPVEPEDFLRAAVQGKIRVIEKFLADGGPPDTCDEFHRTALHRSSLEGHMDILQKLLDSGATVDFRDRVSSASSLDSAAVHWACRGGHLDAVKLLQDRGADLNLKDKLLSTPLHVATRTGHLDIVEHLIHCGVDINSPDREGDTALHDATRLSRYKIIKVLILHGADMMARNLAGKTPTDLVQQWQVDTRQALETKERPQEETEVPA", "length": 340, "header": "tr|A0A8V0ZF46-1|A0A8V0ZLD9_CHICK Computationally mapped isoform of Ankyrin repeat domain 2 OS=Gallus gallus OX=9031 GN=ANKRD2 PE=4 SV=1 CANONICAL=A0A8V0ZLD9-1" }, "locus": { "chromosome": "6", "start_pos": 23113892, "end_pos": 23111927, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049834.1", "url": "https://www.ensembl.org/id/ENSGALT00010049834.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029441.1", "url": "https://www.ensembl.org/id/ENSGALP00010029441.1" } ] } }, { "isoform_ac": "A0A8V0ZLD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9/entry#A0A8V0ZLD9-1", "sequence": { "sequence": "MSPQRLKGDGPREPLAVERMSTPELEEEKRQGPRNRGIEAIKVRALCRGVGCRRAPSWGPTECCMSPQGQDRVRRSSVDLRREIIDVGSIQRLIELRKQRRKRREERAATPEPTPPPEPEEIEGPVEPEDFLRAAVQGKIRVIEKFLADGGPPDTCDEFHRTALHRSSLEGHMDILQKLLDSGATVDFRDRLDSAAVHWACRGGHLDAVKLLQDRGADLNLKDKLLSTPLHVATRTGHLDIVEHLIHCGVDINSPDRVSATPTCSPSPCSLGDAVHRARLLLLQEGDTALHDATRLSRYKIIKVLILHGADMMARNLAGKTPTDLVQQWQVDTRQALETKERPQEETEVPA", "length": 351, "header": "tr|A0A8V0ZLD9-1|A0A8V0ZLD9_CHICK Isoform 1 of Ankyrin repeat domain 2 OS=Gallus gallus OX=9031 GN=ANKRD2 PE=4 SV=1 CANONICAL=A0A8V0ZLD9-1" }, "locus": { "chromosome": "6", "start_pos": 23113539, "end_pos": 23111927, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049829.1", "url": "https://www.ensembl.org/id/ENSGALT00010049829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029438.1", "url": "https://www.ensembl.org/id/ENSGALP00010029438.1" } ] } }, { "isoform_ac": "A0A8V0ZLE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9/entry#A0A8V0ZLE6-1", "sequence": { "sequence": "MWKKRRSSLTRSWRRRKRKRRSPMSPQRLKGDGPREPLAVERMSTPELEEEKRQGPRNRGIEAIKGQDRVRRSSVDLRREIIDVGSIQRLIELRKQRRKRREERAATPEPTPPPEPEEIEGPVEPEDFLRAAVQGKIRVIEKFLADGGPPDTCDEFHRTALHRSSLEGHMDILQKLLDSGATVDFRDRLDSAAVHWACRGGHLDAVKLLQDRGADLNLKDKLLSTPLHVATRTGHLDIVEHLIHCGVDINSPDREGDTALHDATRLSRYKIIKVLILHGADMMARNLAGKTPTDLVQQWQVDTRQALETKERPQEETEVPA", "length": 321, "header": "tr|A0A8V0ZLE6-1|A0A8V0ZLE6_CHICK Computationally mapped isoform of Ankyrin repeat domain 2 OS=Gallus gallus OX=9031 GN=ANKRD2 PE=4 SV=1 CANONICAL=A0A8V0ZLD9-1" }, "locus": { "chromosome": "6", "start_pos": 23113834, "end_pos": 23111927, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049839.1", "url": "https://www.ensembl.org/id/ENSGALT00010049839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029443.1", "url": "https://www.ensembl.org/id/ENSGALP00010029443.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 114, "start_aa": "Thr", "end_pos": 114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr114", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 114 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMD9-1", "uniprot_ac": "A0A8V0ZMD9", "uniprot_id": "A0A8V0ZMD9_CHICK", "mass": { "chemical_mass": 119898.0, "monoisotopic_mass": 119898.0 }, "refseq": { "ac": "XP_004943847", "name": "WD repeat-containing protein 72 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943847" }, "gene_names": [ { "name": "WDR72", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD9" } ] }, { "name": "WDR72", "type": "synonym", "evidence": [ { "id": "XP_004943847", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943847" } ] } ], "protein_names": [ { "name": "WD repeat domain 72", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD9/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 72 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943847", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943847" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943847.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943847" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD9", "locus": { "chromosome": "10", "start_pos": 8434660, "end_pos": 8332079, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021813", "url": "https://www.ensembl.org/id/ENSGALG00010021813" } ] } } ], "crossref": [ { "id": "A0A8V0ZMD9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMD9", "database": "AlphaFoldDB", "categories": [] }, { "id": "427497", "url": "https://www.ncbi.nlm.nih.gov/gene/427497", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049916", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049916", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427497", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427497", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHCSSRM", "url": "https://omabrowser.org/oma/group/YHCSSRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZF99", "url": "https://www.orthodb.org/?gene=A0A8V0ZF99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMD9", "url": "https://www.orthodb.org/?gene=A0A8V0ZMD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44099:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44099:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23123", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23123", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943847", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZF99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVSIPAVAVWGRIAPSHSITAIMITDDQQTIVTGSQEGQICLWDLSSELKISSKEILFGHTASVTCLAKAREFEKQPYVVSATENGEMCVWNVTSGLCIENTKLPYRHTAIYYYHCSFRMTGEGWLLCFGEYQDVLIIDAKTLGVLHTLSSQSSDWINCMCIVHSARIQEDSLVAVSVTGVLKAWDLSSSLTSIQERQNVCEKESKSLGCTNCRAVRFCTYTERLLLVVSSICWQVYDYCDFSLLCTEFCKSGQCFAGGEVLAAYRLIIWTEDGYSYIYQLLNSGLSKSIYPADGKVLKETVYPHLLCFTDVKENKSFPFVMGFMNERKEPFYKILFSGEASGRITLWHVPDVPASTFDGSPQEIPISTTWTLQDNFNKAHSMAEGIIDHLCDSKDGIENAVVTSSVYIPSLDKLVCGCENGEIFITPGLETARARLLENVSLKGNLPHKVLNGHSSRVTCLLYPHGNSVRFDPSWLLSGGQDSTVICWDIFTGKILHRFSLQSGPVTELLRSPENCKLQYHSVVCCVCSDHSVAVLHLQKKVCLLHARKHLFPVKKIKFDPMEGLLIVGCEDDSVYVWEIETGTLERHETGEIAKAILSSIGDSEYLVVDSLHPVSQESKRNKNVQYKSSSSYKRGMISYNLTQTEKSSDKVMDNSLIQQPFTVLPVKPKWNNANFHVLLFDLEKLVDLLLSYQPCGLKSSNSFHNYDTLERAKSTTEKRALTLKRNKTAGFTLSVDGQVDTVYANQVNRDSNTIRPLEESGGIKRQKKMKSSRKTKMQPSGNIDVNITTDTAKLLLSCLLPWGVDKEIDDLCVGQLDILRLQCPVAFGLVSNERHLSLMLPGWKCTDGGVLEEHTLSNLFSKRVLDLSNKYLAATEGRTGERDGTVDNVYGTKGAEIIFFLLSRIVLINRVFNMPSADTSQIESLQQPESVHNKWQNMEAAISSFPSFYGELPRNKSRRHSSDFGNASLLKLICCWSDQSIKIIEAMQAVLLAEVQRTMTTLRKTAVCREPLATVENGNVSVLKHDKSSNSANFQDVEDAPDRCVLEESESPDDMKAHPWISKVCSCKVC", "length": 1073, "header": "tr|A0A8V0ZMD9-1|A0A8V0ZMD9_CHICK Isoform 1 of WD repeat domain 72 OS=Gallus gallus OX=9031 GN=WDR72 PE=4 SV=1 CANONICAL=A0A8V0ZMD9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZF99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD9/entry#A0A8V0ZF99-1", "sequence": { "sequence": "MRVSIPAVAVWGRIAPSHSITAIMITDDQQTIVTGSQEGQICLWDLSSELKISSKEILFGHTASVTCLAKAREFEKQPYVVSATENGEMCVWNVTSGLCIENTKLPYRHTAIYYYHCSFRMTGEGWLLCFGEYQDVLIIDAKTLGVLHTLSSQSSDWINCMCIVHSARIQEDSLVAVSVTGVLKAWDLSSSLTSIQERQNVCEKESKSLGCTNCRAVRFCTYTERLLLVVSSICWQVYDYCDFSLLCTEFCKSGQCFAGGEVLAAYRLIIWTEDGYSYIYQLLNSGLSKSIYPADGKVLKETVYPHLLCFTDVKENKSFPFVMGFMNERKEPFYKILFSGEASGRITLWHVPDVPASTFDGSPQEIPISTTWTLQDNFNKAHSMAEGIIDHLCDSKDGIENAVVTSSVYIPSLDKLVCGCENGEIFITPGLETARARLLENVSLKGNLPHKVLNGHSSRVTCLLYPHGNSVRFDPSWLLSGGQDSTVICWDIFTGKILHRFSLQSGPVTELLRSPENCKLQYHSVVCCVCSDHSVAVLHLQKKVCLLHARKHLFPVKKIKFDPMEGLLIVGCEDDSVYVWEIETGTLERHETGEIAKAILSSIGDSEYLVVDSLHPVSQESKRNKNVQYKSSSSYKRGMISYNLTQTEKSSDKVMDNSLIQQPFTVLPVKPKWNNANFHVLLFDLEKLVDLLLSYQPCGLKSSNSFHNYDTLERAKSTTEKRALTLKRNKTAGFTLSVDGQVDTVYANQVNRDSNTIRPLEESGGIKRQKKMKSSRKTKMQPSGNIDVNITTDTAKLLLSCLLPWGVDKEIDDLCVGQLDILRLQCPVAFGLVSNERHLSLMLPGWKCTDGGVLEEHTLSNLFSKRVLDLSNKYLAATEGRTGERDGTVDNVYGTKGAEIIFFLLSRIVLINRVFNMPSADTSQIESLQQPESVHNKWQNMEAAISSFPSFYGELPRNKSRRHSSDFGNASLLKLICCWSDQSIKIIEAMQAVLLAEVQRTMTTLRKTAVCREPLATVENGNGC", "length": 1024, "header": "tr|A0A8V0ZF99-1|A0A8V0ZMD9_CHICK Computationally mapped isoform of WD repeat domain 72 OS=Gallus gallus OX=9031 GN=WDR72 PE=4 SV=1 CANONICAL=A0A8V0ZMD9-1" }, "locus": { "chromosome": "10", "start_pos": 8397808, "end_pos": 8340279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053079.1", "url": "https://www.ensembl.org/id/ENSGALT00010053079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031971.1", "url": "https://www.ensembl.org/id/ENSGALP00010031971.1" } ] } }, { "isoform_ac": "A0A8V0ZMD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD9/entry#A0A8V0ZMD9-1", "sequence": { "sequence": "MRVSIPAVAVWGRIAPSHSITAIMITDDQQTIVTGSQEGQICLWDLSSELKISSKEILFGHTASVTCLAKAREFEKQPYVVSATENGEMCVWNVTSGLCIENTKLPYRHTAIYYYHCSFRMTGEGWLLCFGEYQDVLIIDAKTLGVLHTLSSQSSDWINCMCIVHSARIQEDSLVAVSVTGVLKAWDLSSSLTSIQERQNVCEKESKSLGCTNCRAVRFCTYTERLLLVVSSICWQVYDYCDFSLLCTEFCKSGQCFAGGEVLAAYRLIIWTEDGYSYIYQLLNSGLSKSIYPADGKVLKETVYPHLLCFTDVKENKSFPFVMGFMNERKEPFYKILFSGEASGRITLWHVPDVPASTFDGSPQEIPISTTWTLQDNFNKAHSMAEGIIDHLCDSKDGIENAVVTSSVYIPSLDKLVCGCENGEIFITPGLETARARLLENVSLKGNLPHKVLNGHSSRVTCLLYPHGNSVRFDPSWLLSGGQDSTVICWDIFTGKILHRFSLQSGPVTELLRSPENCKLQYHSVVCCVCSDHSVAVLHLQKKVCLLHARKHLFPVKKIKFDPMEGLLIVGCEDDSVYVWEIETGTLERHETGEIAKAILSSIGDSEYLVVDSLHPVSQESKRNKNVQYKSSSSYKRGMISYNLTQTEKSSDKVMDNSLIQQPFTVLPVKPKWNNANFHVLLFDLEKLVDLLLSYQPCGLKSSNSFHNYDTLERAKSTTEKRALTLKRNKTAGFTLSVDGQVDTVYANQVNRDSNTIRPLEESGGIKRQKKMKSSRKTKMQPSGNIDVNITTDTAKLLLSCLLPWGVDKEIDDLCVGQLDILRLQCPVAFGLVSNERHLSLMLPGWKCTDGGVLEEHTLSNLFSKRVLDLSNKYLAATEGRTGERDGTVDNVYGTKGAEIIFFLLSRIVLINRVFNMPSADTSQIESLQQPESVHNKWQNMEAAISSFPSFYGELPRNKSRRHSSDFGNASLLKLICCWSDQSIKIIEAMQAVLLAEVQRTMTTLRKTAVCREPLATVENGNVSVLKHDKSSNSANFQDVEDAPDRCVLEESESPDDMKAHPWISKVCSCKVC", "length": 1073, "header": "tr|A0A8V0ZMD9-1|A0A8V0ZMD9_CHICK Isoform 1 of WD repeat domain 72 OS=Gallus gallus OX=9031 GN=WDR72 PE=4 SV=1 CANONICAL=A0A8V0ZMD9-1" }, "locus": { "chromosome": "10", "start_pos": 8434124, "end_pos": 8340279, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053087.1", "url": "https://www.ensembl.org/id/ENSGALT00010053087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031975.1", "url": "https://www.ensembl.org/id/ENSGALP00010031975.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427497", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427497", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LDC8-1", "protein_name": "WD repeat-containing protein 72 isoform X1", "gene_name": "Wdr72", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRSALQAVALWGRKAPPHSITAIMITDDQQTIVTGSQEGQLCLWSLSPELKISAKELLFGHSASVTCLAKARDFSKQPYVVSAAENGEMYVWNVSSGQCVEKATLPYRHTAICYYHCSSRMTGDGWLLCCGEYQDVLIIDAGTLAFLHTFSSSQSPDWMKCMCIVHSVRIQEDSLLVVSVTGELKVWDLSSSINSVQEKQDVYEKESKFLDSVNCQTIRFCTYTERLLLVVFSKCWKVYDYCDFSLLWTEVSRDGQFFAGGEVLAAHRVLVWTEDGHSYIYQLLNRWAQMGAAFRTFSGLSKCICPADGGVLKETIYPHLLCSTSVEENQSLHFVMGYMNERKEPFYKVLFSGEVSGRITLWHIPDVPISKFDGSPREIPVTTTWTLQDNFDKHQTVSQSITDHFSGSRDETGMTATITSSEYIPNLDKLICGCEDGTIFITKALNAAKAGLLEGDSLLRDPPCHALLRGHHQSVTSLLYPHGLASKLDESWMVSGDQGSCVILWDIFKEEILHTFSLESGPVTRLLMSPENLKISDGQILCCVCGDHSVALLHLEGRQCLLRARKHLFPVRTIRWHPVENFLIVGCADDSVYIWEIETGTLERHETGERARIILNCGDNVQFVKSEPTLPVASETHKHKSVEQRSSNAHQPGLVPCPVLQLESSCKVADTTSVPRPFNVLPVKTKWSHIGFHVLLFDLENLVELLLPTPINDVDHSGSFYGSDILRRAKSTVEKKTLTMRRNKASCSSLQAEAQAKPSGDSLPPGDNASKLPEESDGIKRQKKMKSSKKTRPKPSRKVDASFTIDMAKLFLSCVLPWGVDKELDSLCTRHLSILKLQGPVSLGLASNENLFSLMLPGWDACSTEIKEHSGINLFSRKVLELSNKYTATLPNQTGIPRGPDNHCDALQQSDTIVYLLNRLFLVNKLVNMPLDLACETDRPFKVESVHNKGKFPGSDILNISSFYGHLRNGRNEYHTPEVDISLLKLISCWRDQAVQVTEAIQAVLLAEVQQHMKHLKNTPISSQPDPVAEHTICERMLISSKVGWNEEIELPYVGNSYPPKTSVSPVKHGNDLNSANFQDTEDILDRCVLEESESAGQPRRRPWIAQVCSCRMC", "length": 1114 }, "evidence": [ { "id": "A0A8V0ZMD9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMD9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I6GHQ1-1", "protein_name": "WD repeat domain 72", "gene_name": "Wdr72", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSALQAVALWGRKAPPHSITAIMITDDQRTIVTGSQEGQLCLWSLSPELKISAKELLFGHSASVTCLARARDFSKQPYVVSAAENGEMCLWDVSSGQCVEKTTLPYRHTAICYYHCSFRMTGEGWLLCCGEYQDVLVLDAGTLAVLHTFSSSQSPDWMKCMCIVHSVRIQEDSLLVVSVTGELKVWDLSSSINSIQEKQDVYEKESKFLDSFNCQTIRFCTYTERLLLVVFSKCWKIYDYCDFSLLWTEVSRDGQFFAGGEVLAAHRILVWTEDGHSYIYQLLNRWAQMGTAFRTFSGLSKCMCPADGGVLKGTVYPHLLCSTSVEENKSLHFVMGYMNERKEPFYKVLFSGEVSGRITLWHIPDVPISKFDGSPREIPITTTWTLQDNFDKHQMVSQSIADHFSGSRDEVGETVTITSSEYVPNLDKLICGCEDGTIFITKALNAAKAGLLEGGSLLKDSPCHTLLRGHRHSVTSLLYPHSLASKLDQSWMVSGDRGSYVILWDIFTEEILHTFFLEAGPVTRLLMSPENLKRSDGQILCCVCGDHSVALLHLEGRRCLLRARKHLFPVRTIRWHPVENFLIVGCTDDSVYIWEIETGTLERHETGERARIILNCGDDAQLVRSEPTLSVASETHKHKSVEQKSSNSHLPGPVPCPGLQLESSCQVADASSVPRPFNVLPVKTKWSHVGFHVLLFDLENLVELLLPTPLSDVDPSGSFYGSDILRRAKSTVEKKTLTIRRNKASCTSLQAEAQAKSSGETLLPGDSTCKFSEESNGIKRQKKMKSSKKARPKPSRKVDASLTIDMAKLFLSCILPWGVDKELDSLCTRHLSILKLQGPVSLGLASNEDLFSLMLPGWDACNTEMKEYSGVNLCSRKVLDLSNKYTTALLNQTGIPRSLENHCDALQQSDAIVYLLSRLFLVNKLVNMPLDLACETDRPFKMESVHNKVRFPGSDILNLSSFYGHLKNGRHECHTPEADLSLLKLISCWRDQSVQVTEAIQAALLAEVQQHMKSLRDTPVRSQPDPVAEHSICERVQTSAKVEQAEELELQCVGTSSPLKTSVSSVKQGNDLNSANFQDTEDILDRCVLEESESAGQPRHRPWIAKVCSCRMC", "length": 1114 }, "evidence": [ { "id": "A0A8V0ZMD9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3YYM4-1", "protein_name": "WD repeat-containing protein 72", "gene_name": "Wdr72", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGALQAVALWGRKAPPHSITAIMITDDQQTIVTGSQEGQLCLWSLSPELKISAKELLFGHSASVTCLARARDFSKQPYVVSAAENGEMCMWNVSSGQCVEKTSLPYRHTAICYYHCSFRMTGEGWLLCCGEYQDVLVLDAGTLAVLHTFTSLQSPDWMKCMCIVHSVRIQEDSLLVVSITGELKVWDLSSSINSIQEKQDVHEKESKFLDSFNCQTIRFCPYTERLLLVVFSKCWKIYDYCDFSLLWTEVSRDGQFFAGGEVLAAHRILVWTEDGHSYIYQLLNRWAQMGATLRTFSGLSKCVCPADGGVLKGTVYPHLLCSTSVEENKSLHFVMGYMNERKEPFYKVLFSGEVSGRITLWHIPDVPISKFDGSPREIPITTTWTLQDNFDKHQMVSQSITDHFSGSRDEVGMTATITSSEYIPNLDKLICGCEDGTIFITKALNAAKAGLLEGDSLLKDSPCHTLLRGHHQSVTSLLYPHNLASKLDQSWMVSGDRGSYVILWDIFTEEILHTFFLEAGPVTRLLMSPENLKRSDGQILCCVCGDHSVALLHLEGRRCLLRARKHLFPVRMIRWHPVENFLIVGCTDDSVYIWEIETGTLERHETGERARIILNCGDDAQLIRSEPTLSVASETHKHKSIEQKSSNSHQPGPVPCPSVQLESSCKVADASSVPRPFNVLPVKTKWSHIGFHVLLFDLENLVELLLPTPLSDVDPSGSFYGGDILRRAKSTVEKKTLTIRRNKASCSSLQTEAQAKPSGDSLVLGDSTSKFSEENNGIKRQKKMKSSKKAHPKPPRKVDASLTIDMAKLFLSCILPWGVDKDLDSLCTRHLSILKLQGPVSLGLASNEDLFSLMLPGWDACSTEMKEYSGVNLCSRKVLDLSSKYTATLLHQTGIPRGLESHCDSVQQSDAIVYLLSRLFLVNKLVNMPLDLACEIDRPFKMETVHSKARFPGSDILNISSFYGHPKNGGNECRAPEADLSLLKLISCWRDQSVQVTEAIQAVLLAEVQQHMKSLRNTPVSSQPDPVAEHSICERMQISAKMEWTEELELQYVGKSSPLKTSVSPVKHGNDLNSANFQDTEDILDRCVLEESESAGQPRHRPWIAKVCSCRMC", "length": 1114 }, "evidence": [ { "id": "A0A8V0ZMD9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMD9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3MJ13-1", "protein_name": "WD repeat-containing protein 72", "gene_name": "WDR72", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTSLQAVALWGQKAPPHSITAIMITDDQRTIVTGSQEGQLCLWNLSHELKISAKELLFGHSASVTCLARARDFSKQPYIVSAAENGEMCVWNVTNGQCMEKATLPYRHTAICYYHCSFRMTGEGWLLCCGEYQDVLIIDAKTLAVVHSFRSSQFPDWINCMCIVHSMRIQEDSLLVVSVAGELKVWDLSSSINSIQEKQDVYEKESKFLESLNCQTIRFCTYTERLLLVVFSKCWKVYDYCDFSLLLTEVSRNGQFFAGGEVIAAHRILIWTEDGHSYIYQLLNSGLSKSIYPADGRVLKETIYPHLLCSTSVQENKEQSRPFVMGYMNERKEPFYKVLFSGEVSGRITLWHIPDVPVSKFDGSPREIPVTATWTLQDNFDKHDTMSQSIIDYFSGLKDGAGTAVVTSSEYIPSLDKLICGCEDGTIIITQALNAAKARLLEGGSLVKDSPPHKVLKGHHQSVTSLLYPHGLSSKLDQSWMLSGDLDSCVILWDIFTEEILHKFFLEAGPVTSLLMSPEKFKLRGEQIICCVCGDHSVALLHLEGKSCLLHARKHLFPVRMIKWHPVENFLIVGCADDSVYIWEIETGTLERHETGERARIILNCCDDSQLVKSVLPIASETLKHKSIEQRSSSPYQLGPLPCPGLQVESSCKVTDAKFCPRPFNVLPVKTKWSNVGFHILLFDLENLVELLLPTPLSDVDSSSSFYGGEVLRRAKSTVEKKTLTLRKSKTACGPLSAEALAKPITESLAQGDNTIKFSEENDGIKRQKKMKISKKMQPKPSRKVDASLTIDTAKLFLSCLLPWGVDKDLDYLCIKHLNILKLQGPISLGISLNEDNFSLMLPGWDLCNSGMIKDYSGVNLFSRKVLDLSDKYTATLPNQVGIPRGLENNCDSLRESDTIVYLLSRLFLVNKLVNMPLELACRVGSSFRMESIHNKMRGAGNDILNMSSFYSCLRNGKNESHVPEADLSLLKLISCWRDQSVQVTEAIQAVLLAEVQQHMKSLGKIPVNSQPVSMAENGNCEMKQMLPKLEWTEELELQCVRNTLPLQTPVSPVKHDSNSNSANFQDVEDMPDRCALEESESPGEPRHHSWIAKVCPCKVS", "length": 1102 }, "evidence": [ { "id": "A0A8V0ZMD9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMD9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 729, "end_pos": 731, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" }, { "start_pos": 958, "end_pos": 960, "annotation": "n_glycosylation_sequon" }, { "start_pos": 969, "end_pos": 971, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD9" }, { "id": "PF23123", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23123" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WDR72-like alpha-solenoid", "eco_id": "ECO_0000259", "start_pos": 867, "end_pos": 1022, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1022, "end_pos": 1024 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 441, "end_pos": 443 }, { "start_pos": 643, "end_pos": 645 }, { "start_pos": 729, "end_pos": 731 }, { "start_pos": 789, "end_pos": 791 }, { "start_pos": 93, "end_pos": 95 }, { "start_pos": 958, "end_pos": 960 }, { "start_pos": 969, "end_pos": 971 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMG0-1", "uniprot_ac": "A0A8V0ZMG0", "uniprot_id": "A0A8V0ZMG0_CHICK", "mass": { "chemical_mass": 14415.0, "monoisotopic_mass": 14415.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG0", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZMG0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMG0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZFC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLHQETQEVVLVQQASSTSKICCQSFQLSPELCLPQREMSCCRPCVPSPCGASGPTPLASSCSEPCVARCADSTVAIQASAVVVTLPGPILTSFPQNTAVGSSLSAAVGSSLSTAGVPISSGGSLGLGGSGLCLPRPPCSFNC", "length": 144, "header": "tr|A0A8V0ZMG0-1|A0A8V0ZMG0_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZMG0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG0/entry#A0A8V0ZFC0-1", "sequence": { "sequence": "MSCCRPCVPSPCGASGPTPLASSCSEPCVARCADSTVAIQASAVVVTLPGPILTSFPQNTAVGSSLSAAVGSSLSTAGVPISSGGSLGLGGSGLCLPRPPCSFNC", "length": 105, "header": "tr|A0A8V0ZFC0-1|A0A8V0ZMG0_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZMG0-1" }, "locus": { "chromosome": "10", "start_pos": 781097, "end_pos": 780783, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053111.1", "url": "https://www.ensembl.org/id/ENSGALT00010053111.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031993.1", "url": "https://www.ensembl.org/id/ENSGALP00010031993.1" } ] } }, { "isoform_ac": "A0A8V0ZMG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG0/entry#A0A8V0ZMG0-1", "sequence": { "sequence": "MLLHQETQEVVLVQQASSTSKICCQSFQLSPELCLPQREMSCCRPCVPSPCGASGPTPLASSCSEPCVARCADSTVAIQASAVVVTLPGPILTSFPQNTAVGSSLSAAVGSSLSTAGVPISSGGSLGLGGSGLCLPRPPCSFNC", "length": 144, "header": "tr|A0A8V0ZMG0-1|A0A8V0ZMG0_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZMG0-1" }, "locus": { "chromosome": "10", "start_pos": 781097, "end_pos": 780504, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053114.1", "url": "https://www.ensembl.org/id/ENSGALT00010053114.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031995.1", "url": "https://www.ensembl.org/id/ENSGALP00010031995.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 57 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMJ8-1", "uniprot_ac": "A0A8V0ZMJ8", "uniprot_id": "A0A8V0ZMJ8_CHICK", "mass": { "chemical_mass": 153048.0, "monoisotopic_mass": 153048.0 }, "refseq": { "ac": "NP_990254", "name": "protein phosphatase 1 regulatory subunit 9 like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990254" }, "gene_names": [ { "name": "PPP1R19L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ] }, { "name": "PPP1R19AL", "type": "synonym", "evidence": [ { "id": "NP_990254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990254" } ] }, { "name": "PPP1R19L", "type": "synonym", "evidence": [ { "id": "NP_990254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990254" } ] }, { "name": "PPP1R9B", "type": "synonym", "evidence": [ { "id": "NP_990254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990254" } ] } ], "protein_names": [ { "name": "Neurabin-1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8/entry#names_and_taxonomy" } ] }, { "name": "KS5 protein", "type": "synonym", "evidence": [ { "id": "NP_990254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990254" } ] }, { "name": "Neurabin-I", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8/entry#names_and_taxonomy" } ] }, { "name": "Neural tissue-specific F-actin-binding protein I", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8/entry#names_and_taxonomy" } ] }, { "name": "Protein phosphatase 1 regulatory subunit 9A", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 9 like", "type": "synonym", "evidence": [ { "id": "NP_990254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990254" } ] }, { "name": "protein phosphatase 1 regulatory subunit 9A-like", "type": "synonym", "evidence": [ { "id": "NP_990254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990254" } ] }, { "name": "protein phosphatase 1, regulatory (inhibitor) subunit 9B", "type": "synonym", "evidence": [ { "id": "NP_990254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990254" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267659.181338.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1. On or before Oct 4, 2021 this sequence version replaced XP_040559261.1, NP_990254.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_990254", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990254" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPP1R19L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8", "locus": { "chromosome": "7", "start_pos": 17320464, "end_pos": 17277452, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021821", "url": "https://www.ensembl.org/id/ENSGALG00010021821" } ] } } ], "crossref": [ { "id": "cd06790", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06790", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09512", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09512", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395762", "url": "https://www.ncbi.nlm.nih.gov/gene/395762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043446", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043446", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395762", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395762", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TGHREEM", "url": "https://omabrowser.org/oma/group/TGHREEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMJ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZMJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16154", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16154", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16154:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16154:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17817", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17817", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990254", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990254", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFE0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMKTESKGERTLRSASPHRNAYKSDFHAIKCSFDGVNSPENTSNKTGLQQKLSTSSNGGGNDPHSRGRAATYGNRVHKIKSMFLQMGGSTSTPSSESSPPAETKLISRATAAEHGPSPGSTSFLIIQKNNLLNTNTGPSSSPVDSSSVPSTADKIVRSNDEADLDKVALAEKFSETRKLFERNIKQRSSVDRYSPSKCERSEDKRRHGSASDCSSVVDHFNFNTDVSPSLALDKVENQGSELKQQHPSNGSKTSFLNAGPISRRLESFLGDSDTEDSKEISKNDGLDQGPLRGHCSLDSSTTVQRSPEKIASAEVPVIDRDELSEVFEKDKREKAVLGRSLQDMSSISSQEAKWRTETALSQVSPVEETCVELSVQDETSGHGKEGLEKGHVVNEDQPLKYQIQEGKRSSYSLEVVEEFTERKGTNQEEVTDGMTVKDVPVQDVLQQEGDTEEEEQVVEKQRDGFCAFGIENAAFDDYRDTENQDPEDNEILEEEEEYMYDSEYEEFPGLSEEEDPEPDRKVKFSTAPIKVFSTYSNEDYDRRNEEVDPVAASAEYELEKRVEKMEVFPVEIEKGDSGLGISIIGMGVGADQGLEKLGIFVKTITDGGAAQRDGRIQVNDQIVEVDGISLVGVTQFFAATVLKNTKGTVRFLIGREKPGTQSEVARLISETLEQERCLYEQHYVHDDTEQDDEYDDDDDTYESHLHEKSVEVFDLPENEDISLPLDMDSAQSLLKFKELQLKHAVTVAEVNQLKEKLEVVEAEKNEWKLNRAQLQQNLEESKEKIKKLETYWLEAQSLCKTVNEHLKETQEQCDALEKKYNKAKKLLKDYQQKEIEFMKKEEDHSRVLEERDQKYAEQLKMYQEKISELESKLIVYEKMPYMFGSGSLLEDGCQNPSQHNEQSKMREENEKETESVQERLNSSEMLISDFDAFVGDTPRLDTSAHKAKAQLALKVKRQPPSRSKLKESLGAGQQTANLQDEDSEDDILNKEVSTLCLTKTSEISEKLTLPHLDDIERKSEKPEQTQSTESPLESSPSASTHSSPVHKPNSENITTTTHSTPEEVTPNSPQGYTKNVKQKEVKGKGKEAKEEKKSEDRAVETNEGTSSGKSKRRFPDFGGLRKSGGKGKKQEKESVRGSLDSRGSRELLDDSGNNLSASDSDSPVPTCMPFSWFGDSHKEPQVSSSSLHFTQSGQDSCEHGQDKNRSKSRIVIDDTYHSKPSCELSGLVTEPNLSGRSHTLTFSSNEALDDEFTTTGKQNQWHSRPISEWTTQQVCHWLMGMNMEQYITEFTAMNIDGQQLMQLDSDKLKALGVSSQNDRSTIKKKIKDIRKTQEKLEKQKEKVQKKEREVRKTARVVTTLESSC", "length": 1364, "header": "tr|A0A8V0ZMJ8-1|A0A8V0ZMJ8_CHICK Isoform 1 of Neurabin-1 OS=Gallus gallus OX=9031 GN=PPP1R19L PE=1 SV=1 CANONICAL=A0A8V0ZMJ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8/entry#A0A8V0ZFE0-1", "sequence": { "sequence": "MMKTESKGERTLRSASPHRNAYKSDFHAIKCSFDGVNSPENTSNKTGLQQKLSTSSNGGGNDPHSRGRAATYGNRVHKIKSMFLQMGGSTSTPSSESSPPAETKLISRATAAEHGPSPGSTSFLIIQKNNLLNTNTGPSSSPVDSSSVPSTADKIVRSNDEADLDKVALAEKFSETRKLFERNIKQRSSVDRYSPSKCERSEDKRRHGSASDCSSVVDHFNFNTDVSPSLALDKVENQGSELKQQHPSNGSKTSFLNAGPISRRLESFLGDSDTEDSKEISKNDGLDQGPLRGHCSLDSSTTVQRSPEKIASAEVPVIDRDELSEVFEKDKREKAVLGRSLQDMSSISSQEAKWRTETALSQVSPVEETCVELSVQDETSGHGKEGLEKGHVVNEDQPLKYQIQEGKRSSYSLEVVEEFTERKGTNQEEVTDGMTVKDVPVQDVLQQEGDTEEEEQVVEKQRDGFCAFGIENAAFDDYRDTENQDPEDNEILEEEEEYMYDSEYEEFPGLSEEEDPEPDRKVKFSTAPIKVFSTYSNEDYDRRNEEVDPVAASAEYELEKRVEKMEVFPVEIEKGDSGLGISIIGMGVGADQGLEKLGIFVKTITDGGAAQRDGRIQVNDQIVEVDGISLVGVTQFFAATVLKNTKGTVRFLIGREKPGTQSEVARLISETLEQERCLYEQHYVHDDTEQDDEYDDDDDTYESHLHEKSVEVFDLPENEDISLPLDMDSAQSLLKFKELQLKHAVTVAEVNQLKEKLEVVEAEKNEWKLNRAQLQQNLEESKEKIKKLETYWLEAQSLCKTVNEHLKETQEQCDALEKKYNKAKKLLKDYQQKEIEFMKKEEDHSRVLEERDQKYAEQLKMYQEKISELESKLIVYEKMPYMFGSGSLLEDGCQNPSQHNEQSKMREENEKETESVQERLNSSEMLISDFDAFVGDTPRLDTSAHKAKAQLALKVKRQPPSRSKLKESLGAGQQTANLQDEDSEDDILNKEVSTLCLTKTSEISEKLTLPHLDDIERKSEKPEQTQSTESPLESSPSASTHSSPVHKPNSENITTTTHSTPEEVTPNSPQGYTKNVKQKEVKGKGKEAKEEKKSEDRAVETNEGTSSGKSKRRFPDFGGLRKSGGKGKKQEKESVRGSLDSRGSRELLDDSGNNLSASDSDSPVPTCMPFSWFGDSHKEPQVSSSSLHFTQSGQDSCEHGQDKNRSKALDDEFTTTGKQNQWHSRPISEWTTQQVCHWLMGMNMEQYITEFTAMNIDGQQLMQLDSDKLKVCEYLRIDL", "length": 1279, "header": "tr|A0A8V0ZFE0-1|A0A8V0ZMJ8_CHICK Computationally mapped isoform of Neurabin-1 OS=Gallus gallus OX=9031 GN=PPP1R19L PE=1 SV=1 CANONICAL=A0A8V0ZMJ8-1" }, "locus": { "chromosome": "7", "start_pos": 17317187, "end_pos": 17278995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053134.1", "url": "https://www.ensembl.org/id/ENSGALT00010053134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032011.1", "url": "https://www.ensembl.org/id/ENSGALP00010032011.1" } ] } }, { "isoform_ac": "A0A8V0ZMI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8/entry#A0A8V0ZMI6-1", "sequence": { "sequence": "MMKTESKGERTLRSASPHRNAYKSDFHAIKCSFDGQKLSTSSNGGGNDPHSRGRAATYGNRVHKIKSMFLQMGGSTSTPSSESSPPAETKLISRATAAEHGPSPGSTSFLIIQKNNLLNTNTGPSSSPVDSSSVPSTADKIVRSNDEADLDKVALAEKFSETRKLFERNIKQRSSVDRYSPSKCERSEDKRRHGSASDCSSVVDHFNFNTDVSPSLALDKVENQGSELKQQHPSNGSKTSFLNAGPISRRLESFLGDSDTEDSKEISKNDGLDQGPLRGHCSLDSSTTVQRSPEKIASAEVPVIDRDELSEVFEKDKREKAVLGRSLQDMSSISSQEAKWRTETALSQVSPVEETCVELSVQDETSGHGKEGLEKGHVVNEDQPLKYQIQEGKRSSYSLEVVEEFTERKGTNQEEVTDGMTVKDVPVQDVLQQEGDTEEEEQVVEKQRDGFCAFGIENAAFDDYRDTENQDPEDNEILEEEEEYMYDSEYEEFPGLSEEEDPEPDRKVKFSTAPIKVFSTYSNEDYDRRNEEVDPVAASAEYELEKRVEKMEVFPVEIEKGDSGLGISIIGMGVGADQGLEKLGIFVKTITDGGAAQRDGRIQVNDQIVEVDGISLVGVTQFFAATVLKNTKGTVRFLIGREKPGTQSEVARLISETLEQERCLYEQHYVHDDTEQDDEYDDDDDTYESHLHEKSVEVFDLPENEDISLPLDMDSAQSLLKFKELQLKHAVTVAEVNQLKEKLEVVEAEKNEWKLNRAQLQQNLEESKEKIKKLETYWLEAQSLCKTVNEHLKETQEQCDALEKKYNKAKKLLKDYQQKEIEFMKKEEDHSRVLEERDQKYAEQLKMYQEKISELESKLIVYEKMPYMFGSGSLLEDGCQNPSQHNEQSKMREENEKETESVQERLNSSEMLISDFDAFVGDTPRLDTSAHKAKAQLALKVKRQPPSRSKLKESLGAGQQTANLQDEDSEDDILNKEVSTLCLTKTSEISEKLTLPHLDDIERKSEKPEQTQSTESPLESSPSASTHSSPVHKPNSENITTTTHSTPEEVTPNSPQGYTKNVKQKEVKGKGKEAKEEKKSEDRAVETNEGTSSGKSKRRFPDFGGLRKSGGKGKKQEKESVRGSLDSRGSRELLDDSGNNLSASDSDSPVPTCMPFSWFGDSHKEPQVSSSSLHFTQSGQDSCEHGQDKNRSKSRIVIDDTYHSKPSCELSGLVTEPNLSGRSHTLTFSSNEALDDEFTTTGKQNQWHSRPISEWTTQQVCHWLMGMNMEQYITEFTAMNIDGQQLMQLDSDKLKALGVSSQNDRSTIKKKIKDIRKTQEKLEKQKEKVQKKEREVRKTARVVTTLESSC", "length": 1350, "header": "tr|A0A8V0ZMI6-1|A0A8V0ZMI6_CHICK Computationally mapped isoform of Neurabin-1 OS=Gallus gallus OX=9031 GN=PPP1R19L PE=1 SV=1 CANONICAL=A0A8V0ZMJ8-1" }, "locus": { "chromosome": "7", "start_pos": 17319201, "end_pos": 17278995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053150.1", "url": "https://www.ensembl.org/id/ENSGALT00010053150.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032020.1", "url": "https://www.ensembl.org/id/ENSGALP00010032020.1" } ] } }, { "isoform_ac": "A0A8V0ZMJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8/entry#A0A8V0ZMJ8-1", "sequence": { "sequence": "MMKTESKGERTLRSASPHRNAYKSDFHAIKCSFDGVNSPENTSNKTGLQQKLSTSSNGGGNDPHSRGRAATYGNRVHKIKSMFLQMGGSTSTPSSESSPPAETKLISRATAAEHGPSPGSTSFLIIQKNNLLNTNTGPSSSPVDSSSVPSTADKIVRSNDEADLDKVALAEKFSETRKLFERNIKQRSSVDRYSPSKCERSEDKRRHGSASDCSSVVDHFNFNTDVSPSLALDKVENQGSELKQQHPSNGSKTSFLNAGPISRRLESFLGDSDTEDSKEISKNDGLDQGPLRGHCSLDSSTTVQRSPEKIASAEVPVIDRDELSEVFEKDKREKAVLGRSLQDMSSISSQEAKWRTETALSQVSPVEETCVELSVQDETSGHGKEGLEKGHVVNEDQPLKYQIQEGKRSSYSLEVVEEFTERKGTNQEEVTDGMTVKDVPVQDVLQQEGDTEEEEQVVEKQRDGFCAFGIENAAFDDYRDTENQDPEDNEILEEEEEYMYDSEYEEFPGLSEEEDPEPDRKVKFSTAPIKVFSTYSNEDYDRRNEEVDPVAASAEYELEKRVEKMEVFPVEIEKGDSGLGISIIGMGVGADQGLEKLGIFVKTITDGGAAQRDGRIQVNDQIVEVDGISLVGVTQFFAATVLKNTKGTVRFLIGREKPGTQSEVARLISETLEQERCLYEQHYVHDDTEQDDEYDDDDDTYESHLHEKSVEVFDLPENEDISLPLDMDSAQSLLKFKELQLKHAVTVAEVNQLKEKLEVVEAEKNEWKLNRAQLQQNLEESKEKIKKLETYWLEAQSLCKTVNEHLKETQEQCDALEKKYNKAKKLLKDYQQKEIEFMKKEEDHSRVLEERDQKYAEQLKMYQEKISELESKLIVYEKMPYMFGSGSLLEDGCQNPSQHNEQSKMREENEKETESVQERLNSSEMLISDFDAFVGDTPRLDTSAHKAKAQLALKVKRQPPSRSKLKESLGAGQQTANLQDEDSEDDILNKEVSTLCLTKTSEISEKLTLPHLDDIERKSEKPEQTQSTESPLESSPSASTHSSPVHKPNSENITTTTHSTPEEVTPNSPQGYTKNVKQKEVKGKGKEAKEEKKSEDRAVETNEGTSSGKSKRRFPDFGGLRKSGGKGKKQEKESVRGSLDSRGSRELLDDSGNNLSASDSDSPVPTCMPFSWFGDSHKEPQVSSSSLHFTQSGQDSCEHGQDKNRSKSRIVIDDTYHSKPSCELSGLVTEPNLSGRSHTLTFSSNEALDDEFTTTGKQNQWHSRPISEWTTQQVCHWLMGMNMEQYITEFTAMNIDGQQLMQLDSDKLKALGVSSQNDRSTIKKKIKDIRKTQEKLEKQKEKVQKKEREVRKTARVVTTLESSC", "length": 1364, "header": "tr|A0A8V0ZMJ8-1|A0A8V0ZMJ8_CHICK Isoform 1 of Neurabin-1 OS=Gallus gallus OX=9031 GN=PPP1R19L PE=1 SV=1 CANONICAL=A0A8V0ZMJ8-1" }, "locus": { "chromosome": "7", "start_pos": 17319201, "end_pos": 17278995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053164.1", "url": "https://www.ensembl.org/id/ENSGALT00010053164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032031.1", "url": "https://www.ensembl.org/id/ENSGALP00010032031.1" } ] } }, { "isoform_ac": "A0A8V0ZMU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8/entry#A0A8V0ZMU5-1", "sequence": { "sequence": "MMKTESKGERTLRSASPHRNAYKSDFHAIKCSFDGVNSPENTSNKTGLQQKLSTSSNGGGNDPHSRGRAATYGNRVHKIKSMFLQMGGSTSTPSSESSPPAETKLISRATAAEHGPSPGSTSFLIIQKNNLLNTNTGPSSSPVDSSSVPSTADKIVRSNDEADLDKVALAEKFSETRKLFERNIKQRSSVDRYSPSKCERSEDKRRHGSASDCSSVVDHFNFNTDVSPSLALDKVENQGSELKQQHPSNGSKTSFLNAGPISRRLESFLGDSDTEDSKEISKNDGLDQGPLRGHCSLDSSTTVQRSPEKIASAEVPVIDRDELSEVFEKDKREKAVLGRSLQDMSSISSQEAKWRTETALSQVSPVEETCVELSVQDETSGHGKEGLEKGHVVNEDQPLKYQIQEGKRSSYSLEVVEEFTERKGTNQEEVTDGMTVKDVPVQDVLQQEGDTEEEEQVVEKQRDGFCAFGIENAAFDDYRDTENQDPEDNEILEEEEEYMYDSEYEEFPGLSEEEDPEPDRKVKFSTAPIKVFSTYSNEDYDRRNEEVDPVAASAEYELEKRVEKMEVFPVEIEKGDSGLGISIIGMGVGADQGLEKLGIFVKTITDGGAAQRDGRIQVNDQIVEVDGISLVGVTQFFAATVLKNTKGTVRFLIGREKPGTQSEVARLISETLEQERCLYEQHYVHDDTEQDDEYDDDDDTYESHLHEKSVEVFDLPENEDISLPLDMDSAQSLLKFKELQLKHAVTVAEVNQLKEKLEVVEAEKNEWKLNRAQLQQNLEESKEKIKKLETYWLEAQSLCKTVNEHLKETQEQCDALEKKYNKAKKLLKDYQQKEIEFMKKEEDHSRVLEERDQKYAEQLKMYQEKISELESKLIVYEKMPYMFGSGSLLEDGCQNPSQHNEQSKMREENEKETESVQERLNSSEMLISDFDAFVGDTPRLDTSAHKAKAQLALKVKRQPPSRSKLKESLGAGQQTANLQDEDSEDDILNKEVSTLCLTKTSEISEKLTLPHLDDIERKSEKPEQTQSTESPLESSPSASTHSSPVHKPNSENITTTTHSTPEEVTPNSPQGYTKNVKQKEVKGKGKEAKEEKKSEDRAVETNEGTSSGKSKRRFPDFGGLRKSGGKGKKQEKESVRGSLDSRGSRELLDDSGNNLSASDSDSPVPTCMPFSWFGDSHKEPQVSSSSLHFTQSGQDSCEHGQDKNRSKSRIVIDDTYHSKPSCELSGLVTEPNLSGRSHTLTFSSNEALDDEFTTTGKQNQWHSRPISEWTTQQVCHWLMGMNMEQYITEFTAMNIDGQQLMQLDSDKLKALGVSSQNDRSTIKKKIKDIRK", "length": 1331, "header": "tr|A0A8V0ZMU5-1|A0A8V0ZMU5_CHICK Computationally mapped isoform of Neurabin-1 OS=Gallus gallus OX=9031 GN=PPP1R19L PE=1 SV=1 CANONICAL=A0A8V0ZMJ8-1" }, "locus": { "chromosome": "7", "start_pos": 17319102, "end_pos": 17278995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053141.1", "url": "https://www.ensembl.org/id/ENSGALT00010053141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032014.1", "url": "https://www.ensembl.org/id/ENSGALP00010032014.1" } ] } }, { "isoform_ac": "A0A8V0ZT93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8/entry#A0A8V0ZT93-1", "sequence": { "sequence": "MMKTESKGERTLRSASPHRNAYKSDFHAIKCSFDGVNSPENTSNKTGLQQKLSTSSNGGGNDPHSRGRAATYGNRVHKIKSMFLQMGGSTSTPSSESSPPAETKLISRATAAEHGPSPGSTSFLIIQKNNLLNTNTGPSSSPVDSSSVPSTADKIVRSNDEADLDKVALAEKFSETRKLFERNIKQRSSVDRYSPSKCERSEDKRRHGSASDCSSVVDHFNFNTDVSPSLALDKVENQGSELKQQHPSNGSKTSFLNAGPISRRLESFLGDSDTEDSKEISKNDGLDQGPLRGHCSLDSSTTVQRSPEKIASAEVPVIDRDELSEVFEKDKREKAVLGRSLQDMSSISSQEAKWRTETALSQVSPVEETCVELSVQDETSGHGKEGLEKGHVVNEDQPLKYQIQEGKRSSYSLEVVEEFTERKGTNQEEVTDGMTVKDVPVQDVLQQEGDTEEEEQVVEKQRDGFCAFGIENAAFDDYRDTENQDPEDNEILEEEEEYMYDSEYEEFPGLSEEEDPEPDRKVKFSTAPIKVFSTYSNEDYDRRNEEVDPVAASAEYELEKRVEKMEVFPVEIEKGDSGLGISIIGMGVGADQGLEKLGIFVKTITDGGAAQRDGRIQVNDQIVEVDGISLVGVTQFFAATVLKNTKGTVRFLIGREKPGTQSEVARLISETLEQERCLYEQHYVHDDTEQDDEYDDDDDTYESHLHEKSVEVFDLPENEDISLPLDMDSAQSLLKFKELQLKHAVTVAEVNQLKEKLEVVEAEKNEWKLNRAQLQQNLEESKEKIKKLETYWLEAQSLCKTVNEHLKETQEQCDALEKKYNKAKKLLKDYQQKEIEFMKKEEDHSRVLEERDQKYAEQLKMYQEKVKLLYLKTNICLLEDLFLTSTLQFSQISELESKLIVYEKMPYMFGSGSLLEDGCQNPSQHNEQSKMREENEKETESVQERLNSSEMLISDFDAFVGDTPRLDTSAHKAKAQLALKVKRQPPSRSKLKESLGAGQQTANLQDEDSEDDILNKEVSTLCLTKTSEISEKLTLPHLDDIERKSEKPEQTQSTESPLESSPSASTHSSPVHKPNSENITTTTHSTPEEVTPNSPQGYTKNVKQKEVKGKGKEAKEEKKSEDRAVETNEGTSSGKSKRRFPDFGGLRKSGGKGKKQEKESVRGSLDSRGSRELLDDSGNNLSASDSDSPVPTCMPFSWFGDSHKEPQVSSSSLHFTQSGQDSCEHGQDKNRSKALDDEFTTTGKQNQWHSRPISEWTTQQVCHWLMGMNMEQYITEFTAMNIDGQQLMQLDSDKLKALGVSSQNDRSTIKKKIKDIRKTQEKLEKQKEKVQKKEREVRKTARVVTTLESSC", "length": 1351, "header": "tr|A0A8V0ZT93-1|A0A8V0ZMJ8_CHICK Computationally mapped isoform of Neurabin-1 OS=Gallus gallus OX=9031 GN=PPP1R19L PE=1 SV=1 CANONICAL=A0A8V0ZMJ8-1" }, "locus": { "chromosome": "7", "start_pos": 17319201, "end_pos": 17278995, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053160.1", "url": "https://www.ensembl.org/id/ENSGALT00010053160.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032028.1", "url": "https://www.ensembl.org/id/ENSGALP00010032028.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 746, "start_aa": "Thr", "end_pos": 746, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr746", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 92, "start_aa": "Thr", "end_pos": 92, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr92", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395762", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395762", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F571-1", "protein_name": "Neurabin-1", "gene_name": "ppp1r9ala", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIKAESKGERTLRSASPHRNAYKSDFHAIKCSFDGTKSDSEAKSYANGASDPREDSRGRPFGNRVNKIKNIFLQMDGQQPQESQDASPVSPVSPVSKFAVNTNKPNSANSQEPQNTDRKAEEVEIDKVALAEKFSVTRKLFERGIKDQPATERPIPGRTSTRLSHGKVPDDAVRGSRRSFGSSESMNTNSAIKTPPISPVRSVSDEKGIDESKQVNRLSLNAGPISRRLENFIVDGGDDKESTQVIPEKSSRPIQASFQKTSSPATDSTQKPLNADSSHELSSPKSDPISNISPISIKLSSSSSTGELNSPSTNHIPFKRSSSSSGSDLVKPSATNESTKDPKSPSSPCNSSQSPEEPKSDNHIIGSSSREQCLDPAGAGMVRAELVVVQNESSESDDDEDEDLLEDVMTEVKLQRELKSEAPVDDVTHTGDKSLEKKVCLLEETKKRESNAEEEVEEIVQRRRSSCHEDDDEDDDDEESEQEDPDECGKTSPVFYSFENAAFVDDKEAVEDKQKDEDEDEEHDEEYDEVPGLSEDEERPSRRTIRFSTKPIRVYRTFSNEDYDRRNDDVDPVAASAEYELEKRVEKMDVFPVEIEKGDKGLGISIIGMGVGADQGLEKLGIFVKTITEDGAAERDGRIQVNDQIVEVDGISLVGVTQLFAATVLKNTKGSVRFLIGREKPGTQSEVARLISETLEQERQQQQGDDTYEQSTEEDEHYEDEEEGGEDGILGSSFCGRNVEVYDLPESEDMFLPSNMDTTQLTFRFKELQIKHTIAEAEVDELKERLRESSEERAAWEAREAQLERSVQENSERIAQMEKNWLEAQALCKSINEQLNDTQSQYEALDKKYSKAKKLLKDYQQKEAEFEQREEELKRSLDERESAYKSQIEDLQRRLAKLESGRGHNESSLSGSKSADSLLLAGADWSGMVPETERLDTSAHRARAQLAQRSKRQPPSRSKLKETLSSPGGRPQGDDESESLSPESPLLRRRSFQESLSLPVVISSPTNQPKNEGSVMSSSQSGQRDPQSPAVSPPKDSSPSSFARNVKKRESKGKGKEVKDESNDAAGKTKRRFPDFGGLRKSGGKGKKLNKESRASLDSRGSAELLEESGVRVSPSESMTSIPTCMPFSWFGEKDKERDRESSSSSLPYATADASTEHNSKNKTNLSWSSLFSRSLDLSLSVLDDSNPSSPASEFSGLVVEPNLSGRSHTLTFSSSEMLDEESSSGGKDYHWQNRPVSDWTSQQVCHWLMGMNMDQYTPEFSTQAIDGQQLLNLDSDRLKALGVCSQTDRATIKKKLKEMKKAQEKMEKQREKREKEARRSGRLPASTDSVC", "length": 1332 }, "evidence": [ { "id": "A0A8V0ZMJ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZMJ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" }, { "name": "calcium-mediated signaling", "id": "GO:0019722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" }, { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1052, "end_pos": 1054, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1154, "end_pos": 1156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1204, "end_pos": 1206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1232, "end_pos": 1234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 921, "end_pos": 923, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ8" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", 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{ "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKU5-1", "uniprot_ac": "A0A8V0ZKU5", "uniprot_id": "A0A8V0ZKU5_CHICK", "mass": { "chemical_mass": 23056.0, "monoisotopic_mass": 23056.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZKU5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKU5", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0ZFF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSFSGTDISSSTVQGWLTWPEMLKSFVPELRSRPKPANHAPPRRQMVGATATVSTLATVVGQPKTPAGNQSRERCRRESGEWRWAEGLQDVPTSAGKGGLRRGLPCLPSMDSMSAVSSPQISPASYASLMATCGGDNRQLAAGDVPTCVPLRPWRPPAGAGFPLICVHHQVLGSDRMRCRCRHSVPSHSSVSPVFPLLRLPTTPPLSPPRSQCP", "length": 215, "header": "tr|A0A8V0ZKU5-1|A0A8V0ZKU5_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZKU5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU5/entry#A0A8V0ZFF2-1", "sequence": { "sequence": "MSSFSGTDISSSTVQGWLTWPEMLKSFVPELRSRPKPANHAPPRRQMVGATATVSTLATVVGQPKTPAGNQSRERCRRESGEWRWAEGLQDVPTSAGKGGLRRGLPCLPSMDSMSAVSSPQMYAPAPLTTKTSKA", "length": 135, "header": "tr|A0A8V0ZFF2-1|A0A8V0ZKU5_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZKU5-1" }, "locus": { "chromosome": "5", "start_pos": 602860, "end_pos": 602456, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053149.1", "url": "https://www.ensembl.org/id/ENSGALT00010053149.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032019.1", "url": "https://www.ensembl.org/id/ENSGALP00010032019.1" } ] } }, { "isoform_ac": "A0A8V0ZFF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU5/entry#A0A8V0ZFF8-1", "sequence": { "sequence": "MSSFSGTDISSSTVQGWLTWPEMLKSFVPELRSRPKPANHAPPRRQMVGATATVSTLATVVGQPKTPAGNQSRERCRRESGEWRWAEGLQDVPTSAGKGGLRRGLPCLPSMDSMSAVSSPQISPASYASLMATCGGDNRQLAAGDVPTCVPLRPWRPPAGAGFPLICVHHQSPRRSAPCSLRARHGGCEHPHPPAAPRPSPAAHLHSCRP", "length": 210, "header": "tr|A0A8V0ZFF8-1|A0A8V0ZKU5_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZKU5-1" }, "locus": { "chromosome": "5", "start_pos": 604048, "end_pos": 602456, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053159.1", "url": "https://www.ensembl.org/id/ENSGALT00010053159.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032027.1", "url": "https://www.ensembl.org/id/ENSGALP00010032027.1" } ] } }, { "isoform_ac": "A0A8V0ZKU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU5/entry#A0A8V0ZKU5-1", "sequence": { "sequence": "MSSFSGTDISSSTVQGWLTWPEMLKSFVPELRSRPKPANHAPPRRQMVGATATVSTLATVVGQPKTPAGNQSRERCRRESGEWRWAEGLQDVPTSAGKGGLRRGLPCLPSMDSMSAVSSPQISPASYASLMATCGGDNRQLAAGDVPTCVPLRPWRPPAGAGFPLICVHHQVLGSDRMRCRCRHSVPSHSSVSPVFPLLRLPTTPPLSPPRSQCP", "length": 215, "header": "tr|A0A8V0ZKU5-1|A0A8V0ZKU5_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZKU5-1" }, "locus": { "chromosome": "5", "start_pos": 603302, "end_pos": 602456, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053154.1", "url": "https://www.ensembl.org/id/ENSGALT00010053154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032024.1", "url": "https://www.ensembl.org/id/ENSGALP00010032024.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMU0-1", "uniprot_ac": "A0A8V0ZMU0", "uniprot_id": "A0A8V0ZMU0_CHICK", "mass": { "chemical_mass": 247426.0, "monoisotopic_mass": 247426.0 }, "refseq": { "ac": "XP_015130905", "name": "protein PRR14L isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130905" }, "gene_names": [ { "name": "PRR14L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU0" } ] }, { "name": "PRR14L", "type": "synonym", "evidence": [ { "id": "XP_015130905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130905" } ] } ], "protein_names": [ { "name": "Proline rich 14 like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU0/entry#names_and_taxonomy" } ] }, { "name": "protein PRR14L isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015130905", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130905" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015130905.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015130905", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130905" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRR14L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU0", "locus": { "chromosome": "15", "start_pos": 8916150, "end_pos": 8897366, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021933", "url": "https://www.ensembl.org/id/ENSGALG00010021933" } ] } } ], "crossref": [ { "id": "416957", "url": "https://www.ncbi.nlm.nih.gov/gene/416957", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416957", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416957", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EICSWPE", "url": "https://omabrowser.org/oma/group/EICSWPE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFQ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZFQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL27", "url": "https://www.orthodb.org/?gene=A0A8V0ZL27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL37", "url": "https://www.orthodb.org/?gene=A0A8V0ZL37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMU0", "url": "https://www.orthodb.org/?gene=A0A8V0ZMU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14522", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14522", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14522:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14522:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015130905", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015130905", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSSGVECLLDSSACTGTEDLHKGLPLSIPAGLMAVSEPGAGLDAKPDVSTPELACSNELSSEHHRTLEAKGFGEGAAHLDDMVREVHWEPAELLTEELLNDGDVENNEENKQTRRKQDCSSGERQQGGKEAKDAEEDHAECCVLNPGGKWLKQEAPHLSKHEVNSSATCCTEIAAFLKIKGENQANVQVTAETLPKLTEEAQGMKADGTRIFSKAGYQNGSVSKGLPPESDECPDTDTVMARAGVSETTRLDFIEPLKVMDVESTTEHSQEISEYNGLKAHADMSLRTEGNVVSILETTEEKLPRQNLANEFSTSLDNCQTYQQEEENNTCDFCTVLPPRHNEPVRLSSVGSCRMLSIKSSQGMCSVLESVCYLDFRNMSLDNNSTAIHGIINETSKKHLPESMTSQTNYDHRTGFVKDCISKSMPVEHLSALSNKELSGDKTDDGETNDSTGKSYSSEFEEAAEIQREIAVGGNTDAQESAHFEHCHPSVFSSIAIQDLSVKQEDESPEVQLFEQKSQSNTMLEFSGKETNLIYALNVLLPPVAQKSREPHCDECLFCTANEAASKDKAQDNLSGKESFGSSGTTEEQVAEFVLHKDKFKSSINPKASDESSITGHISQKNRKSSEGKVESVDAGLENEHSNTWNSSNQTLKDQHTAATTSSILSSSTPVDDAVLESNFFKADIEMKIDENDSSEGEISGGYGSKKTISFLEEHCPLSCRSLPYQDDWGNRCVALRGINDISTEKSMFFLTYDAEESTATLVGDDISNKNMESENMKQFNLCKLTDCSEIICDKDEAKDQFSVCAVHRDEFDKIGNWRSKTGEQLLVRNLNKKNYVHNFEFCNSPLLLKMRELGISGKKGMSSLTASSEYSFSICGACPLFNNMNMQTRRAIQTEMTISPMENQFLAHQSEVYGLVPGRKQHVESLNKEPNTGLQYIATSAEEAKLSISSSQHEDMLLKKGDDLTLIVHKHVREDGFQRTVKENAVDFESSSGLRNTDYSACTGFVSDVIQEKMTKLKEKENSCGREDKGIHEESFFDSKSQYSQHGLASKCVKDKAELVFSGNTTQQSLAKMKWLTGDQANTVNISFLPFSSIHGSLFYKPKKMHVLSEMENRSLRIKSILNNSCSQLMLEPGKETDADKDMGPSCFVKFNIQDSSNDTHGDSETLSALNLANSLPQKEKLFVSSENTGIDNSDSSSDEICCKGSSVTKPLSVTIYIRREASNTEIQSSEDEKATSSLKGAKSQTVCACNKERQRVERHGVLTARVMDVTLLKSADCGEKLKYACTEEKMEREVSYKKKLPIHSLLDGENCLWASLEGSEESSSKTVTVSTENYEKGFEEIPRPDLSSLSKEKNATKPASFTHPSLLSEAVQDCQTAGASDTETSPEFKYNEMNMLSNSCKESLPNYVAQCEVCVPYKLNAQSKDNTKEITGCQDAIPAHSVSMENETSDSVRFDKVDKCQARKRKKKYEEVKVHGSDKAKQEKKAAYKAKAKVAVHPSILYSSELLCSSSNELVMSRNTKFASPSKDIFVVRSSENKLCSTLQEIKRPKITTDTTSSRFLKTQDSEMENLNLKSGYNGILGAFGTRNKLRGPLPLKIQPGRTCKKVPTSYQLDTVRKIKKTKSSTLLEPPLEMPPKQENTVLKSLYFAYKSPTVKKEIAMRFVHMPRQKAKRCSLLSSLKFRKCTKEPALLSKLSAIASKLLVPATSIHTLESLPYSSEILPVAARYSQRRSKNLLEAFSCINRNLHSRWADSWCTKMFSFQSLALYSVGSTKIPSLESSNNSPSSFLNTPVFPISFHIKLDSSPVTDLTRTTSQHSVHHRLVLEEMPAPPSKWTFLLSQSCSDATAIKEDSSQDHELHAPLSVTTPEVVALHPDHRRNAIAKRTGSCSMLGLHTVLALSSPGCYRIWTRRRNLTSHIPTIQRLFISQFNQGLKGASNVSDDLVSSLPYSLGRALSIWSQHGPSARPSEITPLHSSHCKWQPSVGIENSYAILPHLPVQGMEALQTAGHEICLEPPFPLPLPNSCLLSEALPPMLPEPELQVHALDEADTSIPDCLRSQDDTELKKTEPEKRPKKVSQIRIRKTVPRLDHNLTPMGLPKPKRLKKKEFSLEEIYTNKNYKSPPPARSLETIFEEPKEKNGHLISVSQQKRKRILEFQDFTVPRKRKARGKIKAVGSFTRAKKAAPQSAELDALLSQKLMDLEEFFAKEDEQELSSSTGGSHELKMVQ", "length": 2231, "header": "tr|A0A8V0ZMU0-1|A0A8V0ZMU0_CHICK Isoform 1 of Proline rich 14 like OS=Gallus gallus OX=9031 GN=PRR14L PE=4 SV=1 CANONICAL=A0A8V0ZMU0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU0/entry#A0A8V0ZFQ6-1", "sequence": { "sequence": "MLSSGVECLLDSSACTGTEDLHKGLPLSIPAGLMAVSEPGAGLDAKPDVSTPELACSNELSSEHHRTLEAKGFGEGAAHLDDMVREVHWEPAELLTEELLNDGDVENNEENKQTRRKQDCSSGERQQGGKEAKDAEEDHAECCVLNPGGKWLKQEAPHLSKHEVNSSATCCTEIAAFLKIKGENQANVQVTAETLPKLTEEAQGMKADGTRIFSKAGYQNGSVSKGLPPESDECPDTDTVMARAGVSETTRLDFIEPLKVMDVESTTEHSQEISEYNGLKAHADMSLRTEGNVVSILETTEEKLPRQNLANEFSTSLDNCQTYQQEEENNTCDFCTVLPPRHNEPVRLSSVGSCRMLSIKSSQGMCSVLESVCYLDFRNMSLDNNSTAIHGIINETSKKHLPESMTSQTNYDHRTGFVKDCISKSMPVEHLSALSNKELSGDKTDDGETNDSTGKSYSSEFEEAAEIQREIAVGGNTDAQESAHFEHCHPSVFSSIAIQDLSVKQEDESPEVQLFEQKSQSNTMLEFSGKETNLIYALNVLLPPVAQKSREPHCDECLFCTANEAASKDKAQDNLSGKESFGSSGTTEEQVAEFVLHKDKFKSSINPKASDESSITGHISQKNRKSSEGKVESVDAGLENEHSNTWNSSNQTLKDQHTAATTSSILSSSTPVDDAVLESNFFKADIEMKIDENDSSEGEISGGYGSKKTISFLEEHCPLSCRSLPYQDDWGNRCVALRGINDISTEKSMFFLTYDAEESTATLVGDDISNKNMESENMKQFNLCKLTDCSEIICDKDEAKDQFSVCAVHRDEFDKIGNWRSKTGEQLLVRNLNKKNYVHNFEFCNSPLLLKMRELGISGKKGMSSLTASSEYSFSICGACPLFNNMNMQTRRAIQTEMTISPMENQFLAHQSEVYGLVPGRKQHVESLNKEPNTGLQYIATSAEEAKLSISSSQHEDMLLKKGDDLTLIVHKHVREDGFQRTVKENAVDFESSSGLRNTDYSACTGFVSDVIQEKMTKLKEKENSCGREDKGIHEESFFDSKSQYSQHGLASKCVKDKAELVFSGNTTQQSLAKMKWLTGDQANTVNISFLPFSSIHGSLFYKPKKMHVLSEMENRSLRIKSILNNSCSQLMLEPGKETDADKDMGPSCFVKFNIQDSSNDTHGDSETLSALNLANSLPQKEKLFVSSENTGIDNSDSSSDEICCKGSSVTKPLSVTIYIRREASNTEIQSSEDEKATSSLKGAKSQTVCACNKERQRVERHGVLTARVMDVTLLKSADCGEKLKYACTEEKMEREVSYKKKLPIHSLLDGENCLWASLEGSEESSSKTVTVSTENYEKGFEEIPRPDLSSLSKEKNATKPASFTHPSLLSEAVQDCQTAGASDTETSPEFKYNEMNMLSNSCKESLPNYVAQCEVCVPYKLNAQSKDNTKEITGCQDAIPAHSVSMENETSDSVRFDKVDKCQARKRKKKYEEVKVHGSDKAKQEKKAAYKAKAKVAVHPSILYSSELLCSSSNELVMSRNTKFASPSKDIFVVRSSENKLCSTLQEIKRPKITTDTTSSRFLKTQDSEMENLNLKSGYNGILGAFGTRNKLRGPLPLKIQPGRTCKKVPTSYQLDTVRKIKKTKSSTLLEPPLEMPPKQENTVLKSLYFAYKSPTVKKEIAMRFVHMPRQKAKRCSLLSSLKFRKCTKEPALLSKLSAIASKLLVPATSIHTLESLPYSSEILPVAARYSQRRSKNLLEAFSCINRNLHSRWADSWCTKMFSFQSLALYSVGSTKIPSLESSNNSPSSFLNTPVFPISFHIKLDSSPVTDLTRTTSQHSVHHRLVLEEMPAPPSKWTFLLSQSCSDATAIKEDSSQDHELHAPLSVTTPEVVALHPDHRRNAIAKRTGSCSMLGLHTVLALSSPGCYRIWTRRRNLTSHIPTIQRLFISQFNQGLKGASNVSDDLVSSLPYSLGRALSIWSQHGPSARPSEITPLHSSHCKWQPSVGIENSIPVWL", "length": 1998, "header": "tr|A0A8V0ZFQ6-1|A0A8V0ZMU0_CHICK Computationally mapped isoform of Proline rich 14 like OS=Gallus gallus OX=9031 GN=PRR14L PE=4 SV=1 CANONICAL=A0A8V0ZMU0-1" }, "locus": { "chromosome": "15", "start_pos": 8909197, "end_pos": 8898479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053322.1", "url": "https://www.ensembl.org/id/ENSGALT00010053322.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032134.1", "url": "https://www.ensembl.org/id/ENSGALP00010032134.1" } ] } }, { "isoform_ac": "A0A8V0ZL27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU0/entry#A0A8V0ZL27-1", "sequence": { "sequence": "MLSSGVECLLDSSACTGTEDLHKGLPLSIPAGLMAVSEPGAGLDAKPDVSTPELACSNELSSEHHRTLEAKGFGEGAAHLDDMVREVHWEPAELLTEELLNDGDVENNEENKQTRRKQDCSSGERQQGGKEAKDAEEDHAECCVLNPGGKWLKQEAPHLSKHEVNSSATCCTEIAAFLKIKGENQANVQVTAETLPKLTEEAQGMKADGTRIFSKAGYQNGSVSKGLPPESDECPDTDTVMARAGVSETTRLDFIEPLKVMDVESTTEHSQEISEYNGLKAHADMSLRTEGNVVSILETTEEKLPRQNLANEFSTSLDNCQTYQQEEENNTCDFCTVLPPRHNEPVRLSSVGSCRMLSIKSSQGMCSVLESVCYLDFRNMSLDNNSTAIHGIINETSKKHLPESMTSQTNYDHRTGFVKDCISKSMPVEHLSALSNKELSGDKTDDGETNDSTGKSYSSEFEEAAEIQREIAVGGNTDAQESAHFEHCHPSVFSSIAIQDLSVKQEDESPEVQLFEQKSQSNTMLEFSGKETNLIYALNVLLPPVAQKSREPHCDECLFCTANEAASKDKAQDNLSGKESFGSSGTTEEQVAEFVLHKDKFKSSINPKASDESSITGHISQKNRKSSEGKVESVDAGLENEHSNTWNSSNQTLKDQHTAATTSSILSSSTPVDDAVLESNFFKADIEMKIDENDSSEGEISGGYGSKKTISFLEEHCPLSCRSLPYQDDWGNRCVALRGINDISTEKSMFFLTYDAEESTATLVGDDISNKNMESENMKQFNLCKLTDCSEIICDKDEAKDQFSVCAVHRDEFDKIGNWRSKTGEQLLVRNLNKKNYVHNFEFCNSPLLLKMRELGISGKKGMSSLTASSEYSFSICGACPLFNNMNMQTRRAIQTEMTISPMENQFLAHQSEVYGLVPGRKQHVESLNKEPNTGLQYIATSAEEAKLSISSSQHEDMLLKKGDDLTLIVHKHVREDGFQRTVKENAVDFESSSGLRNTDYSACTGFVSDVIQEKMTKLKEKENSCGREDKGIHEESFFDSKSQYSQHGLASKCVKDKAELVFSGNTTQQSLAKMKWLTGDQANTVNISFLPFSSIHGSLFYKPKKMHVLSEMENRSLRIKSILNNSCSQLMLEPGKETDADKDMGPSCFVKFNIQDSSNDTHGDSETLSALNLANSLPQKEKLFVSSENTGIDNSDSSSDEICCKGSSVTKPLSVTIYIRREASNTEIQSSEDEKATSSLKGAKSQTVCACNKERQRVERHGVLTARVMDVTLLKSADCGEKLKYACTEEKMEREVSYKKKLPIHSLLDGENCLWASLEGSEESSSKTVTVSTENYEKGFEEIPRPDLSSLSKEKNATKPASFTHPSLLSEAVQDCQTAGASDTETSPEFKYNEMNMLSNSCKESLPNYVAQCEVCVPYKLNAQSKDNTKEITGCQDAIPAHSVSMENETSDSVRFDKVDKCQARKRKKKYEEVKVHGSDKAKQEKKAAYKAKAKVAVHPSILYSSELLCSSSNELVMSRNTKFASPSKDIFVVRSSENKLCSTLQEIKRPKITTDTTSSRFLKTQDSEMENLNLKSGYNGILGAFGTRNKLRGPLPLKIQPGRTCKKVPTSYQLDTVRKIKKTKSSTLLEPPLEMPPKQENTVLKSLYFAYKSPTVKKEIAMRFVHMPRQKAKRCSLLSSLKFRKCTKEPALLSKLSAIASKLLVPATSIHTLESLPYSSEILPVAARYSQRRSKNLLEAFSCINRNLHSRWADSWCTKMFSFQSLALYSVGSTKIPSLESSNNSPSSFLNTPVFPISFHIKLDSSPVTDLTRTTSQHSVHHRLVLEEMPAPPSKWTFLLSQSCSDATAIKEDSSQDHELHAPLSVTTPEVVALHPDHRRNAIAKRTGSCSMLGLHTVLALSSPGCYRIWTRRRNLTSHIPTIQRLFISQFNQGLKGASNVSDDLVSSLPYSLGRALSIWSQHGPSARPSEITPLHSSHCKWQPSVGIENRIYNAER", "length": 1999, "header": "tr|A0A8V0ZL27-1|A0A8V0ZL27_CHICK Computationally mapped isoform of Proline rich 14 like OS=Gallus gallus OX=9031 GN=PRR14L PE=4 SV=1 CANONICAL=A0A8V0ZMU0-1" }, "locus": { "chromosome": "15", "start_pos": 8907580, "end_pos": 8898479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053317.1", "url": "https://www.ensembl.org/id/ENSGALT00010053317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032131.1", "url": "https://www.ensembl.org/id/ENSGALP00010032131.1" } ] } }, { "isoform_ac": "A0A8V0ZL37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU0/entry#A0A8V0ZL37-1", "sequence": { "sequence": "MLSSGVECLLDSSACTGTEDLHKGLPLSIPAGLMAVSEPGAGLDAKPDVSTPELACSNELSSEHHRTLEAKGFGEGAAHLDDMVREVHWEPAELLTEELLNDGDVENNEENKQTRRKQDCSSGERQQGGKEAKDAEEDHAECCVLNPGGKWLKQEAPHLSKHEVNSSATCCTEIAAFLKIKGENQANVQVTAETLPKLTEEAQGMKADGTRIFSKAGYQNGSVSKGLPPESDECPDTDTVMARAGVSETTRLDFIEPLKVMDVESTTEHSQEISEYNGLKAHADMSLRTEGNVVSILETTEEKLPRQNLANEFSTSLDNCQTYQQEEENNTCDFCTVLPPRHNEPVRLSSVGSCRMLSIKSSQGMCSVLESVCYLDFRNMSLDNNSTAIHGIINETSKKHLPESMTSQTNYDHRTGFVKDCISKSMPVEHLSALSNKELSGDKTDDGETNDSTGKSYSSEFEEAAEIQREIAVGGNTDAQESAHFEHCHPSVFSSIAIQDLSVKQEDESPEVQLFEQKSQSNTMLEFSGKETNLIYALNVLLPPVAQKSREPHCDECLFCTANEAASKDKAQDNLSGKESFGSSGTTEEQVAEFVLHKDKFKSSINPKASDESSITGHISQKNRKSSEGKVESVDAGLENEHSNTWNSSNQTLKDQHTAATTSSILSSSTPVDDAVLESNFFKADIEMKIDENDSSEGEISGGYGSKKTISFLEEHCPLSCRSLPYQDDWGNRCVALRGINDISTEKSMFFLTYDAEESTATLVGDDISNKNMESENMKQFNLCKLTDCSEIICDKDEAKDQFSVCAVHRDEFDKIGNWRSKTGEQLLVRNLNKKNYVHNFEFCNSPLLLKMRELGISGKKGMSSLTASSEYSFSICGACPLFNNMNMQTRRAIQTEMTISPMENQFLAHQSEVYGLVPGRKQHVESLNKEPNTGLQYIATSAEEAKLSISSSQHEDMLLKKGDDLTLIVHKHVREDGFQRTVKENAVDFESSSGLRNTDYSACTGFVSDVIQEKMTKLKEKENSCGREDKGIHEESFFDSKSQYSQHGLASKCVKDKAELVFSGNTTQQSLAKMKWLTGDQANTVNISFLPFSSIHGSLFYKPKKMHVLSEMENRSLRIKSILNNSCSQLMLEPGKETDADKDMGPSCFVKFNIQDSSNDTHGDSETLSALNLANSLPQKEKLFVSSENTGIDNSDSSSDEICCKGSSVTKPLSVTIYIRREASNTEIQSSEDEKATSSLKGAKSQTVCACNKERQRVERHGVLTARVMDVTLLKSADCGEKLKYACTEEKMEREVSYKKKLPIHSLLDGENCLWASLEGSEESSSKTVTVSTENYEKGFEEIPRPDLSSLSKEKNATKPASFTHPSLLSEAVQDCQTAGASDTETSPEFKYNEMNMLSNSCKESLPNYVAQCEVCVPYKLNAQSKDNTKEITGCQDAIPAHSVSMENETSDSVRFDKVDKCQARKRKKKYEEVKVHGSDKAKQEKKAAYKAKAKVAVHPSILYSSELLCSSSNELVMSRNTKFASPSKDIFVVRSSENKLCSTLQEIKRPKITTDTTSSRFLKTQDSEMENLNLKSGYNGILGAFGTRNKLRGPLPLKIQPGRTCKKVPTSYQLDTVRKIKKTKSSTLLEPPLEMPPKQENTVLKSLYFAYKSPTVKKEIAMRFVHMPRQKAKRCSLLSSLKFRKCTKEPALLSKLSAIASKLLVPATSIHTLESLPYSSEILPVAARYSQRRSKNLLEAFSCINRNLHSRWADSWCTKMFSFQSLALYSVGSTKIPSLESSNNSPSSFLNTPVFPISFHIKLDSSPVTDLTRTTSQHSVHHRLVLEEMPAPPSKWTFLLSQSCSDATAIKEDSSQDHELHAPLSVTTPEVVALHPDHRRNAIAKRTGSCSMLGLHTVLALSSPGCYRIWTRRRNLTSHIPTIQRLFISQFNQGLKGASNVSDDLVSSLPYSLGRALSIWSQHGPSARPSEITPLHSSHCKWQPSVGIENSYAILPHLPVQGMEALQTAGHEIWLKKKEFSLEEIYTNKNYKSPPPARSLETIFEEPKEKNGHLISVSQQKRKRILEFQDFTVPRKRKARGKIKAVGSFTRAKKAAPQSAELDALLSQKLMDLEEFFAKEDEQELSSSTGGSHELKMVQ", "length": 2141, "header": "tr|A0A8V0ZL37-1|A0A8V0ZL37_CHICK Computationally mapped isoform of Proline rich 14 like OS=Gallus gallus OX=9031 GN=PRR14L PE=4 SV=1 CANONICAL=A0A8V0ZMU0-1" }, "locus": { "chromosome": "15", "start_pos": 8912834, "end_pos": 8898479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053330.1", "url": "https://www.ensembl.org/id/ENSGALT00010053330.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032141.1", "url": "https://www.ensembl.org/id/ENSGALP00010032141.1" } ] } }, { "isoform_ac": "A0A8V0ZMU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU0/entry#A0A8V0ZMU0-1", "sequence": { "sequence": "MLSSGVECLLDSSACTGTEDLHKGLPLSIPAGLMAVSEPGAGLDAKPDVSTPELACSNELSSEHHRTLEAKGFGEGAAHLDDMVREVHWEPAELLTEELLNDGDVENNEENKQTRRKQDCSSGERQQGGKEAKDAEEDHAECCVLNPGGKWLKQEAPHLSKHEVNSSATCCTEIAAFLKIKGENQANVQVTAETLPKLTEEAQGMKADGTRIFSKAGYQNGSVSKGLPPESDECPDTDTVMARAGVSETTRLDFIEPLKVMDVESTTEHSQEISEYNGLKAHADMSLRTEGNVVSILETTEEKLPRQNLANEFSTSLDNCQTYQQEEENNTCDFCTVLPPRHNEPVRLSSVGSCRMLSIKSSQGMCSVLESVCYLDFRNMSLDNNSTAIHGIINETSKKHLPESMTSQTNYDHRTGFVKDCISKSMPVEHLSALSNKELSGDKTDDGETNDSTGKSYSSEFEEAAEIQREIAVGGNTDAQESAHFEHCHPSVFSSIAIQDLSVKQEDESPEVQLFEQKSQSNTMLEFSGKETNLIYALNVLLPPVAQKSREPHCDECLFCTANEAASKDKAQDNLSGKESFGSSGTTEEQVAEFVLHKDKFKSSINPKASDESSITGHISQKNRKSSEGKVESVDAGLENEHSNTWNSSNQTLKDQHTAATTSSILSSSTPVDDAVLESNFFKADIEMKIDENDSSEGEISGGYGSKKTISFLEEHCPLSCRSLPYQDDWGNRCVALRGINDISTEKSMFFLTYDAEESTATLVGDDISNKNMESENMKQFNLCKLTDCSEIICDKDEAKDQFSVCAVHRDEFDKIGNWRSKTGEQLLVRNLNKKNYVHNFEFCNSPLLLKMRELGISGKKGMSSLTASSEYSFSICGACPLFNNMNMQTRRAIQTEMTISPMENQFLAHQSEVYGLVPGRKQHVESLNKEPNTGLQYIATSAEEAKLSISSSQHEDMLLKKGDDLTLIVHKHVREDGFQRTVKENAVDFESSSGLRNTDYSACTGFVSDVIQEKMTKLKEKENSCGREDKGIHEESFFDSKSQYSQHGLASKCVKDKAELVFSGNTTQQSLAKMKWLTGDQANTVNISFLPFSSIHGSLFYKPKKMHVLSEMENRSLRIKSILNNSCSQLMLEPGKETDADKDMGPSCFVKFNIQDSSNDTHGDSETLSALNLANSLPQKEKLFVSSENTGIDNSDSSSDEICCKGSSVTKPLSVTIYIRREASNTEIQSSEDEKATSSLKGAKSQTVCACNKERQRVERHGVLTARVMDVTLLKSADCGEKLKYACTEEKMEREVSYKKKLPIHSLLDGENCLWASLEGSEESSSKTVTVSTENYEKGFEEIPRPDLSSLSKEKNATKPASFTHPSLLSEAVQDCQTAGASDTETSPEFKYNEMNMLSNSCKESLPNYVAQCEVCVPYKLNAQSKDNTKEITGCQDAIPAHSVSMENETSDSVRFDKVDKCQARKRKKKYEEVKVHGSDKAKQEKKAAYKAKAKVAVHPSILYSSELLCSSSNELVMSRNTKFASPSKDIFVVRSSENKLCSTLQEIKRPKITTDTTSSRFLKTQDSEMENLNLKSGYNGILGAFGTRNKLRGPLPLKIQPGRTCKKVPTSYQLDTVRKIKKTKSSTLLEPPLEMPPKQENTVLKSLYFAYKSPTVKKEIAMRFVHMPRQKAKRCSLLSSLKFRKCTKEPALLSKLSAIASKLLVPATSIHTLESLPYSSEILPVAARYSQRRSKNLLEAFSCINRNLHSRWADSWCTKMFSFQSLALYSVGSTKIPSLESSNNSPSSFLNTPVFPISFHIKLDSSPVTDLTRTTSQHSVHHRLVLEEMPAPPSKWTFLLSQSCSDATAIKEDSSQDHELHAPLSVTTPEVVALHPDHRRNAIAKRTGSCSMLGLHTVLALSSPGCYRIWTRRRNLTSHIPTIQRLFISQFNQGLKGASNVSDDLVSSLPYSLGRALSIWSQHGPSARPSEITPLHSSHCKWQPSVGIENSYAILPHLPVQGMEALQTAGHEICLEPPFPLPLPNSCLLSEALPPMLPEPELQVHALDEADTSIPDCLRSQDDTELKKTEPEKRPKKVSQIRIRKTVPRLDHNLTPMGLPKPKRLKKKEFSLEEIYTNKNYKSPPPARSLETIFEEPKEKNGHLISVSQQKRKRILEFQDFTVPRKRKARGKIKAVGSFTRAKKAAPQSAELDALLSQKLMDLEEFFAKEDEQELSSSTGGSHELKMVQ", "length": 2231, "header": "tr|A0A8V0ZMU0-1|A0A8V0ZMU0_CHICK Isoform 1 of Proline rich 14 like OS=Gallus gallus OX=9031 GN=PRR14L PE=4 SV=1 CANONICAL=A0A8V0ZMU0-1" }, "locus": { "chromosome": "15", "start_pos": 8912834, "end_pos": 8898479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053326.1", "url": "https://www.ensembl.org/id/ENSGALT00010053326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032138.1", "url": "https://www.ensembl.org/id/ENSGALP00010032138.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416957", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416957", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1066, "end_pos": 1068, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1087, "end_pos": 1089, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1115, "end_pos": 1117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1125, "end_pos": 1127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1160, "end_pos": 1162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1357, "end_pos": 1359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1449, "end_pos": 1451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1785, "end_pos": 1787, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1917, "end_pos": 1919, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1942, "end_pos": 1944, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2095, "end_pos": 2097, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 574, "end_pos": 576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 647, "end_pos": 649, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU0" }, { "id": "PF15386", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15386" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tantalus-like", "eco_id": "ECO_0000259", "start_pos": 2096, "end_pos": 2153, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1066, "end_pos": 1068 }, { "start_pos": 1087, "end_pos": 1089 }, { "start_pos": 1115, "end_pos": 1117 }, { "start_pos": 1125, "end_pos": 1127 }, { "start_pos": 1160, "end_pos": 1162 }, { "start_pos": 1357, "end_pos": 1359 }, { "start_pos": 1449, "end_pos": 1451 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 1785, "end_pos": 1787 }, { "start_pos": 1917, "end_pos": 1919 }, { "start_pos": 1942, "end_pos": 1944 }, { "start_pos": 2095, "end_pos": 2097 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 574, "end_pos": 576 }, { "start_pos": 647, "end_pos": 649 }, { "start_pos": 650, "end_pos": 652 }, { "start_pos": 693, "end_pos": 695 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZM58-1", "uniprot_ac": "A0A8V0ZM58", "uniprot_id": "A0A8V0ZM58_CHICK", "mass": { "chemical_mass": 64350.0, "monoisotopic_mass": 64350.0 }, "refseq": {}, "gene_names": [ { "name": "MCOLN2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" } ] } ], "protein_names": [ { "name": "Mucolipin TRP cation channel 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZM58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MCOLN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58", "locus": { "chromosome": "8", "start_pos": 16137823, "end_pos": 16117390, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020811", "url": "https://www.ensembl.org/id/ENSGALG00010020811" } ] } } ], "crossref": [ { "id": "A0A8V0ZM58", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZM58", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008722", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008722", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424531", "url": "https://www.ncbi.nlm.nih.gov/gene/424531", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424531", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424531", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QECKDWN", "url": "https://omabrowser.org/oma/group/QECKDWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZFW2", "url": "https://www.orthodb.org/?gene=A0A8V0ZFW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM53", "url": "https://www.orthodb.org/?gene=A0A8V0ZM53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM58", "url": "https://www.orthodb.org/?gene=A0A8V0ZM58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BWI2", "url": "https://www.orthodb.org/?gene=E1BWI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12127:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12127:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZFW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWI2", "url": "https://www.uniprot.org/uniprotkb/E1BWI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BWI2-1", "url": "https://www.uniprot.org/uniprotkb/E1BWI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVTAVQSVMESNECKALHYTNMMAQSDLDLKETALKEDLKFYFMNPCDKYRARHQIPWKLALQILKIVMVTSQLVFFGLSNQLVVSFKEENTVAFKHLFLKGYSGVDEDDYSCSIYTQQDAYDSIFYVIDQYRQLKNISLGTLGYEHDGSGLKICKQQYRKGGMLPSNDKPNIDVSTETDCITLKPQELAGKNTEVKLNSSFFNLEFYRLIQVKISFKLKGVALQTIHARELPDCYAFQNTITFNNRAHSGKIKVYFNSDTDIQECKDWHILGSVLQKNSLYILVFDGFVILNCLASLILCSRSVVLALRLRQRFVNFFLEKYNRCVSYTDRMEFINGWYVLVIISDVMTIIGSILKMEIKAKNLTSYDVCSILLGTSTLFVWVGVIRYLGYFQTYNVLILTMQASLPKVLRFCCCAGMIYLGYTFCGWIVLGPYHEKFEDLNTVAECLFSLVNGDDMFATFAQIQQKSMLVWIFSRLYLYSFIILFIYMILSLFIALITDAYDTIKKYQQSGFLATDLHEFLKDCGNVSYRKEQTSMPSICCCRRRQSDDNLILIN", "length": 558, "header": "tr|A0A8V0ZM58-1|A0A8V0ZM58_CHICK Isoform 1 of Mucolipin TRP cation channel 2 OS=Gallus gallus OX=9031 GN=MCOLN2 PE=4 SV=1 CANONICAL=A0A8V0ZM58-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58/entry#A0A8V0ZFW2-1", "sequence": { "sequence": "MEISLKRLPGGRAPSCGNMMAQSDLDLKETALKEDLKFYFMNPCDKYRARHQIPWKLALQILKIVMVTSQLVFFGLSNQLVVSFKEENTVAFKHLFLKGYSGVDEDDYSCSIYTQQDAYDSIFYVIDQYRQLKNISLGTLGYEHDGSGLKICKQQYRKGGMLPSNDKPNIDVSTETDCITLKPQELAGKNTEVKLNSSFFNLEFYRLLSTIELTVEKSKSILIVILIFKNAKTGTYLVLCSRKTVCTF", "length": 248, "header": "tr|A0A8V0ZFW2-1|A0A8V0ZM58_CHICK Computationally mapped isoform of Mucolipin TRP cation channel 2 OS=Gallus gallus OX=9031 GN=MCOLN2 PE=4 SV=1 CANONICAL=A0A8V0ZM58-1" }, "locus": { "chromosome": "8", "start_pos": 16129158, "end_pos": 16118036, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050329.1", "url": "https://www.ensembl.org/id/ENSGALT00010050329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029729.1", "url": "https://www.ensembl.org/id/ENSGALP00010029729.1" } ] } }, { "isoform_ac": "A0A8V0ZM53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58/entry#A0A8V0ZM53-1", "sequence": { "sequence": "MEISLKRLPGGRAPSCGNMMAQSDLDLKETALKEDLKFYFMNPCDKYRARHQIPWKLALQILKIVMVTSQLVFFGLSNQLVVSFKEENTVAFKHLFLKGYSGVDEDDYSCSIYTQQDAYDSIFYVIDQYRQLKNISLGTLGYEHDGSGLKICKQQYRKGGMLPSNDKPNIDVSTETDCITLKPQELAGKNTEVKLNSSFFNLEFYRLIQVKISFKLKGVALQTIHARELPDCYAFQNTITFNNRAHSGKIKVYFNSDTDIQECKDWHILGSVLQKNSLYILVFDGFVILNCLASLILCSRSVVLALRLRQRFVNFFLEKYNRCVSYTDRMEFINGWYVLVIISDVMTIIGSILKMEIKAKNLTSYDVCSILLGTSTLFVWVGVIRYLGYFQTYNVLILTMQASLPKVLRFCCCAGMIYLGYTFCGWIVLGPYHEKFEDLNTVAECLFSLVNGDDMFATFAQIQQKSMLVWIFSRLYLYSFIILFIYMILSLFIALITDAYDTIKKYQQSGFLATDLHEFLKDCGNVSYRKEQTSMPSICCCRRRQSDDNLILIN", "length": 554, "header": "tr|A0A8V0ZM53-1|A0A8V0ZM53_CHICK Computationally mapped isoform of Mucolipin TRP cation channel 2 OS=Gallus gallus OX=9031 GN=MCOLN2 PE=4 SV=1 CANONICAL=A0A8V0ZM58-1" }, "locus": { "chromosome": "8", "start_pos": 16136981, "end_pos": 16118036, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050355.1", "url": "https://www.ensembl.org/id/ENSGALT00010050355.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029741.1", "url": "https://www.ensembl.org/id/ENSGALP00010029741.1" } ] } }, { "isoform_ac": "A0A8V0ZM58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58/entry#A0A8V0ZM58-1", "sequence": { "sequence": "MLVTAVQSVMESNECKALHYTNMMAQSDLDLKETALKEDLKFYFMNPCDKYRARHQIPWKLALQILKIVMVTSQLVFFGLSNQLVVSFKEENTVAFKHLFLKGYSGVDEDDYSCSIYTQQDAYDSIFYVIDQYRQLKNISLGTLGYEHDGSGLKICKQQYRKGGMLPSNDKPNIDVSTETDCITLKPQELAGKNTEVKLNSSFFNLEFYRLIQVKISFKLKGVALQTIHARELPDCYAFQNTITFNNRAHSGKIKVYFNSDTDIQECKDWHILGSVLQKNSLYILVFDGFVILNCLASLILCSRSVVLALRLRQRFVNFFLEKYNRCVSYTDRMEFINGWYVLVIISDVMTIIGSILKMEIKAKNLTSYDVCSILLGTSTLFVWVGVIRYLGYFQTYNVLILTMQASLPKVLRFCCCAGMIYLGYTFCGWIVLGPYHEKFEDLNTVAECLFSLVNGDDMFATFAQIQQKSMLVWIFSRLYLYSFIILFIYMILSLFIALITDAYDTIKKYQQSGFLATDLHEFLKDCGNVSYRKEQTSMPSICCCRRRQSDDNLILIN", "length": 558, "header": "tr|A0A8V0ZM58-1|A0A8V0ZM58_CHICK Isoform 1 of Mucolipin TRP cation channel 2 OS=Gallus gallus OX=9031 GN=MCOLN2 PE=4 SV=1 CANONICAL=A0A8V0ZM58-1" }, "locus": { "chromosome": "8", "start_pos": 16136981, "end_pos": 16117466, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050373.1", "url": "https://www.ensembl.org/id/ENSGALT00010050373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029746.1", "url": "https://www.ensembl.org/id/ENSGALP00010029746.1" } ] } }, { "isoform_ac": "E1BWI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58/entry#E1BWI2-1", "sequence": { "sequence": "MMAQSDLDLKETALKEDLKFYFMNPCDKYRARHQIPWKLALQILKIVMVTSQLVFFGLSNQLVVSFKEENTVAFKHLFLKGYSGVDEDDYSCSIYTQQDAYDSIFYVIDQYRQLKNISLGTLGYEHDGSGLKICKQQYRKGGMLPSNDKPNIDVSTETDCITLKPQELAGKNTEVKLNSSFFNLEFYRLIQVKISFKLKGVALQTIHARELPDCYAFQNTITFNNRAHSGKIKVYFNSDTDIQECKDWHILGSVLQKNSLYILVFDGFVILNCLASLILCSRSVVLALRLRQRFVNFFLEKYNRCVSYTDRMEFINGWYVLVIISDVMTIIGSILKMEIKAKNLTSYDVCSILLGTSTLFVWVGVIRYLGYFQTYNVLILTMQASLPKVLRFCCCAGMIYLGYTFCGWIVLGPYHEKFEDLNTVAECLFSLVNGDDMFATFAQIQQKSMLVWIFSRLYLYSFIILFIYMILSLFIALITDAYDTIKKYQQSGFLATDLHEFLKDCGNVSYRKEQTSMPSICCCRRRQSDDNLILIN", "length": 536, "header": "tr|E1BWI2-1|A0A8V0ZM58_CHICK Computationally mapped isoform of Mucolipin TRP cation channel 2 OS=Gallus gallus OX=9031 GN=MCOLN2 PE=4 SV=3 CANONICAL=A0A8V0ZM58-1" }, "locus": { "chromosome": "8", "start_pos": 16136981, "end_pos": 16119948, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050347.1", "url": "https://www.ensembl.org/id/ENSGALT00010050347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029738.1", "url": "https://www.ensembl.org/id/ENSGALP00010029738.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424531", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424531", "resource": "KEGG Pathway" }, { "id": "R-GGA-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SAG5-1", "protein_name": "Mucolipin TRP cation channel 2", "gene_name": "MCOLN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGREVLDLPVWSRTSGPSHGPHCRDAMAHLDSEVKEERLREDLKFYFMNPCEKFRARQQIPWKLGLQILKIVMVTSQLVRFGLSNQLVVAFKEENIVAFKHLFLRGYSGTDEDDYSCSVFTQEDTYESIFFAINQYHRLGNLSLGTLGYGEKEDSRIGLKVCKQHYKKGTMFPSNETLNIDSDVEIDCIHLGLQALSNNPQDWKNSSFFKLEFYRLLQIEISFQLKGIDLQTIYSRELPDCYVFQNMITFDNKAHSGKIKIYFNSDANIEECKDLNISGSIQRNIQYVLVFDAFVIVICLASLILCTRSIVLALRLRKRFLNFFLEKYKRHVCNTDQWEFVNGWYVLVIISDLMTIVGSILKMEIKVKNLTNYDLCSILLGTSTLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHNKFEKLNTVAECLFSLVNGDDMYATFAHIQQKSLLVWLFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKYQKNGFPATDLQEFLKECSSKEKCQQESSAFLPRICCLRRNGSDDHLILVN", "length": 566 }, "evidence": [ { "id": "A0A8V0ZM58", "url": "https://omabrowser.org/oma/group/A0A8V0ZM58/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8IZK6-1", "protein_name": "Mucolipin-2", "gene_name": "MCOLN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARQPYRFPQARIPERGSGVFRLTVRNAMAHRDSEMKEECLREDLKFYFMSPCEKYRARRQIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGYSGTDEDDYSCSVYTQEDAYESIFFAINQYHQLKDITLGTLGYGENEDNRIGLKVCKQHYKKGTMFPSNETLNIDNDVELDCVQLDLQDLSKKPPDWKNSSFFRLEFYRLLQVEISFHLKGIDLQTIHSRELPDCYVFQNTIIFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVICLASLILCTRSIVLALRLRKRFLNFFLEKYKRPVCDTDQWEFINGWYVLVIISDLMTIIGSILKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHDKFENLNTVAECLFSLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQKESSAFLSCICCRRRKRSDDHLIPIS", "length": 566 }, "evidence": [ { "id": "A0A8V0ZM58", "url": "https://omabrowser.org/oma/group/A0A8V0ZM58/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K595-1", "protein_name": "Mucolipin-2", "gene_name": "Mcoln2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGDEETLDLPAWNRVPDLTWGPHHRSAMASLDSEVREECLREDLKFYFMSPCEKYRARRQIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGFSGVDEDDYSCSIYTQENTYESIFFAIKQYRHLKNISLATLGYGESEDNRTGLKVCKQHYKTGAMFSSNETLNIDSDIETDCIHLDLQVLTTEPEDWAQTSFFRLDFYRLVQVDISFALKGIDLQAVHSREIPDCYLFQNTITFDNTAHSGKIKIYLNSEANIEECKNMNISGSTQRSTHYLLVFDVFVIMICLASLILCTRSIVLALRLRKRFLNFFLEKYKQRVCGADQWEFVNGWYVLVTISDLMTIIGSILKMEIKAKKLTNYDVCSILLGTSTLFVWVGVIRYLGYFQTYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHEKFENLNIVAECLFSLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMVLSLFIALITDSYHTIKKYQQHGFPETDLQKFLKESGSKDGYQKQPSALLSCLCCLRRRRSNDHLILID", "length": 566 }, "evidence": [ { "id": "A0A8V0ZM58", "url": "https://omabrowser.org/oma/group/A0A8V0ZM58/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" } ], "pmid": "" }, { "name": "NAADP-sensitive calcium-release channel activity", "id": "GO:0072345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072345", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" } ], "pmid": "" }, { "name": "iron ion transmembrane transporter activity", "id": "GO:0005381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YTN5-1", "A0A8V0YTP2-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZM58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" }, { "id": "PF21381", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21381" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mucolipin extracytosolic", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 268, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZM58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM58" }, { "id": "PF08016", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Polycystin cation channel PKD1/PKD2", "eco_id": "ECO_0000259", "start_pos": 371, "end_pos": 507, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 529, "end_pos": 531 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLA2-1", "uniprot_ac": "A0A8V0ZLA2", "uniprot_id": "A0A8V0ZLA2_CHICK", "mass": { "chemical_mass": 70860.0, "monoisotopic_mass": 70860.0 }, "refseq": {}, "gene_names": [ { "name": "GLMN", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ] } ], "protein_names": [ { "name": "Glomulin, FKBP associated protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLMN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2", "locus": { "chromosome": "8", "start_pos": 13955708, "end_pos": 13935984, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021980", "url": "https://www.ensembl.org/id/ENSGALG00010021980" } ] } } ], "crossref": [ { "id": "A0A8V0ZLA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "424503", "url": "https://www.ncbi.nlm.nih.gov/gene/424503", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424503", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424503", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZFY5", "url": "https://www.orthodb.org/?gene=A0A8V0ZFY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLA2", "url": "https://www.orthodb.org/?gene=A0A8V0ZLA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN16", "url": "https://www.orthodb.org/?gene=A0A8V0ZN16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTQ9", "url": "https://www.orthodb.org/?gene=A0A8V0ZTQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15430:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15430:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08568", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08568", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZFY5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSAVAAVVNFSMPEGQTQTIMAVDELQAIIQRCQILEEADFRGEDYNLFQVAGQKCLEDGYAAQLLEVIQNVKNKVIIKNMGWNLISPLVRCILAYKQEDEKRELCLKILDQLVQLCNPKELFLGLLEQIEQTSGEQVCQTIMLLLQPLQTVLLKLQNKKAYSVGLSLAMIMNQLTPLPVPYTKQQIQEDKLGLCQCCNAVVDFAKPFVNEVVKNMEKSSECNDTELKEELLKFCMKSLKYPLLTAQLEELEGIEEHPFRRFAAEIIDILLDMRELMPLVFLHHKSRRSLWENQEFEDIERKNSADSLACLSYLVFVQHFGINCFPMVFSSSYLLQCNMAHIEVLLKRTEESMLSKGLDLFESCLLRMEDNGLLHQYLEFREFINVSQDLVKVMTLCPIEHLRKKSLNILQLFIDKFEAEGKYTLFRCLLKTSNHAGVEGYVIKNIKDQIHLSLTKAHDNVWFTGHHLISLLDLVLLLPEGAETDLLQYSDRIMASLNLLRYLVIKDCESDNQTGVWTALAKIEENFLKPLHVGLNMSKAHYEAEIKNKKENRKEAHSSNTICSLTVSGEKMPPMTTEMQLQVLHSALFTFDLIESVLARVEELIEVKVKAVMDENI", "length": 618, "header": "tr|A0A8V0ZLA2-1|A0A8V0ZLA2_CHICK Isoform 1 of Glomulin, FKBP associated protein OS=Gallus gallus OX=9031 GN=GLMN PE=4 SV=1 CANONICAL=A0A8V0ZLA2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZFY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2/entry#A0A8V0ZFY5-1", "sequence": { "sequence": "MPEGQTQTIMAVDELQAIIQRCQILEEADFRGEDYNLFQVAGQKCLEDGYAAQLLEVIQNVKNKVIIKNMGWNLISPLVRCILAYKQEDEKRELCLKILDQLVQLCNPKELFLGLLEQIEQTSGEQVCQTIMLLLQPLQTVLLKLQNKKAYSVGLSLAMIMNQLTPLPVPYTKQQIQEDKLGLCQCCNAVVDFAKPFVNEVVKNMEKSSECNDTELKEELLKFCMKSLKYPLLTAQLEELEGIEEHPFRRFAAEIIDILLDMRELMPLVFLHHKSRRSLWENQEFEDIERKNSADSLACLSYLVFVQHFGINCFPMVFSSSYLLQCNMAHIEVLLKRTEESMLSKGLDLFESCLLRMEDNGLLHQYLEFREFINVSQDLVKVMTLCPIEHLRKKSLNILQLFIDKFEAEGKYTLFRCLLKTSNHAGVEGYVIKNIKDQIHLSLTKAHDNVWFTGHHLISLLDLVLLLPEGAETDLLQYSDRIMASLNLLRYLVIKDCESDNQTGVWTALAKIEENFLKPLHVGLNMSKAHYEAEIKNKKENRKEAHSSNTICSLTVSGEKMPPMTTEMQLQVLHSALFTFDLIESVLARVEELIEVKVKAVMDENI", "length": 606, "header": "tr|A0A8V0ZFY5-1|A0A8V0ZLA2_CHICK Computationally mapped isoform of Glomulin, FKBP associated protein OS=Gallus gallus OX=9031 GN=GLMN PE=4 SV=1 CANONICAL=A0A8V0ZLA2-1" }, "locus": { "chromosome": "8", "start_pos": 13954640, "end_pos": 13937539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053460.1", "url": "https://www.ensembl.org/id/ENSGALT00010053460.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032220.1", "url": "https://www.ensembl.org/id/ENSGALP00010032220.1" } ] } }, { "isoform_ac": "A0A8V0ZLA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2/entry#A0A8V0ZLA2-1", "sequence": { "sequence": "MRSAVAAVVNFSMPEGQTQTIMAVDELQAIIQRCQILEEADFRGEDYNLFQVAGQKCLEDGYAAQLLEVIQNVKNKVIIKNMGWNLISPLVRCILAYKQEDEKRELCLKILDQLVQLCNPKELFLGLLEQIEQTSGEQVCQTIMLLLQPLQTVLLKLQNKKAYSVGLSLAMIMNQLTPLPVPYTKQQIQEDKLGLCQCCNAVVDFAKPFVNEVVKNMEKSSECNDTELKEELLKFCMKSLKYPLLTAQLEELEGIEEHPFRRFAAEIIDILLDMRELMPLVFLHHKSRRSLWENQEFEDIERKNSADSLACLSYLVFVQHFGINCFPMVFSSSYLLQCNMAHIEVLLKRTEESMLSKGLDLFESCLLRMEDNGLLHQYLEFREFINVSQDLVKVMTLCPIEHLRKKSLNILQLFIDKFEAEGKYTLFRCLLKTSNHAGVEGYVIKNIKDQIHLSLTKAHDNVWFTGHHLISLLDLVLLLPEGAETDLLQYSDRIMASLNLLRYLVIKDCESDNQTGVWTALAKIEENFLKPLHVGLNMSKAHYEAEIKNKKENRKEAHSSNTICSLTVSGEKMPPMTTEMQLQVLHSALFTFDLIESVLARVEELIEVKVKAVMDENI", "length": 618, "header": "tr|A0A8V0ZLA2-1|A0A8V0ZLA2_CHICK Isoform 1 of Glomulin, FKBP associated protein OS=Gallus gallus OX=9031 GN=GLMN PE=4 SV=1 CANONICAL=A0A8V0ZLA2-1" }, "locus": { "chromosome": "8", "start_pos": 13954640, "end_pos": 13937373, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053456.1", "url": "https://www.ensembl.org/id/ENSGALT00010053456.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032217.1", "url": "https://www.ensembl.org/id/ENSGALP00010032217.1" } ] } }, { "isoform_ac": "A0A8V0ZN16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2/entry#A0A8V0ZN16-1", "sequence": { "sequence": "MPEGQTQTIMAVDELQAIIQRCQILEEADFRGEDYNLFQVAGQKCLEDGYAAQLLEVIQNVKNKVIIKNMGWNLISPLVRCILAYKQEDEKRELCLKILDQLVQLCNPKELFLGLLEQIEQTSGEQVCQTIMLLLQPLQTVLLKLQNKKAYSVGLSLAMIMNQLTPLPVPYTKQQIQEDKLGLCQCCNAVVDFAKPFVNEVVKNMEKSSECNDTELKEELLKFCMKSLKYPLLTAQLEELEGIEEHPFRRFAAEIIDILLDMRELMPLVFLHHKSRRSLWENQEFEDIERKNSADSLACLSYLVFVQHFGINCFPMVFSSSYLLQCNMAHIEVLLKRTEESMLSKGLDLFESCLLRMEDNGLLHQYLEFREFINVSQDLVKVMTLCPIEHLRKKSLNILQLFIDKFEAEGKYTLFRCLLKTSNHAGVEGYVIKNIKDQIHLSLTKAHDNVWFTGHHLISLLDLVLLLPEGAETDLLQYSDRIMASLNLLRYLVIKDCESDNQTGVWTALAKIEENFLKPLHVGLNMSKAHYEAEIKNKKENRKVSRFVIVVLSAVSSLSGREKPAAIFWIKISLSSYTSLDVKRHTVLTQFVL", "length": 593, "header": "tr|A0A8V0ZN16-1|A0A8V0ZN16_CHICK Computationally mapped isoform of Glomulin, FKBP associated protein OS=Gallus gallus OX=9031 GN=GLMN PE=4 SV=1 CANONICAL=A0A8V0ZLA2-1" }, "locus": { "chromosome": "8", "start_pos": 13954360, "end_pos": 13937539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053452.1", "url": "https://www.ensembl.org/id/ENSGALT00010053452.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032214.1", "url": "https://www.ensembl.org/id/ENSGALP00010032214.1" } ] } }, { "isoform_ac": "A0A8V0ZTQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2/entry#A0A8V0ZTQ9-1", "sequence": { "sequence": "MPEGQTQTIMAVDELQAIIQRCQILEEADFRGEDYNLFQVAGQKCLEDGYAAQLLEVIQNVKNKVIIKNMGWNLISPLVRCILAYKQEDEKRELCLKILDQLVQLCNPKELFLGLLEQIEQTSGEQVCQTIMLLLQPLQTVLLKLQNKKAYSVGLSLAMIMNQLTPLPVPYTKQQIQEDKLGLCQCCNAVVDFAKPFVNEVVKNMEKSSECNDTELKEELLKFCMKSLKYPLLTAQLEELEGIEEHPFRRFAAEIIDILLDMRELMPLVFLHHKSRRSLWENQEFEDIERKNSADSLACLSYLVFVQHFGINCFPMVFSSSYLLQCNMAHIEVLLKRTEESMLSKGLDLFESCLLRMEDNGLLHQYLEFREFINVSQDLVKVMTLCAETDLLQYSDRIMASLNLLRYLVIKDCESDNQTGVWTALAKIEENFLKPLHVGLNMSKAHYEAEIKNKKENRKEAHSSNTICSLTVSGEKMPPMTTEMQLQVLHSALFTFDLIESVLARVEELIEVKVKAVMDENI", "length": 522, "header": "tr|A0A8V0ZTQ9-1|A0A8V0ZLA2_CHICK Computationally mapped isoform of Glomulin, FKBP associated protein OS=Gallus gallus OX=9031 GN=GLMN PE=4 SV=1 CANONICAL=A0A8V0ZLA2-1" }, "locus": { "chromosome": "8", "start_pos": 13954640, "end_pos": 13937539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053464.1", "url": "https://www.ensembl.org/id/ENSGALT00010053464.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032221.1", "url": "https://www.ensembl.org/id/ENSGALP00010032221.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424503", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424503", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Cul4A-RING E3 ubiquitin ligase complex", "id": "GO:0031464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031464", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" }, { "name": "Cul2-RING ubiquitin ligase complex", "id": "GO:0031462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031462", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hepatocyte growth factor receptor binding", "id": "GO:0005171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005171", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" }, { "name": "ubiquitin-protein transferase inhibitor activity", "id": "GO:0055105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055105", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "vasculogenesis", "id": "GO:0001570", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001570", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" }, { "name": "negative regulation of T cell proliferation", "id": "GO:0042130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" }, { "name": "positive regulation of cytokine production", "id": "GO:0001819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" }, { "name": "positive regulation of phosphorylation", "id": "GO:0042327", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042327", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" }, { "name": "epigenetic regulation of gene expression", "id": "GO:0040029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0040029", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" }, { "name": "muscle cell differentiation", "id": "GO:0042692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042692", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 224, "end_pos": 226 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 537, "end_pos": 539 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMG6-1", "uniprot_ac": "A0A8V0ZMG6", "uniprot_id": "A0A8V0ZMG6_CHICK", "mass": { "chemical_mass": 203641.0, "monoisotopic_mass": 203641.0 }, "refseq": {}, "gene_names": [ { "name": "CEP152", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6" } ] } ], "protein_names": [ { "name": "Centrosomal protein 152", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEP152", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6", "locus": {} } ], "crossref": [ { "id": "IPR051235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057664", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057664", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGB5", "url": "https://www.orthodb.org/?gene=A0A8V0ZGB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGC0", "url": "https://www.orthodb.org/?gene=A0A8V0ZGC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMG6", "url": "https://www.orthodb.org/?gene=A0A8V0ZMG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10337:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10337:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25769", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25769", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380259", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380284", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620912", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8854518", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZGB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLDFDSGALQTQHEDEDYDQEDYAREQELQQLLTDLPHDMLEDSGDQLSNYSDSSIHETEEQSQEARKPDGRWNDHLLINDAQNGYEQGQNLYPDQFLCDQQNDHVEKHAKNWNGLHSSEQMKHLYDVKEDYSGQNSQEDPDDIYLDRDGFNAPGCYQQSNLYHLPENFRPYTNGHNPEFNSQQNQIINFPDAPKEHLKQPFVTSEVVSGQSAESYKVMYKPYQNDVHKKIPVTQEGMRRNEVFEDLHHEFSGNDENSSENMQILQLKALNKARERRVEELNEKLEKSAQQIRYLSHQLSMVTDEKDGLAVSLHESQKLYQNGKEREVYLEGQIKALETQIQTLTTNEEQILKQSRVAEVAMESMQKQLLELQRSDTLQRAREQHDAIVTALKQKHEKQVVSLEQKLDATKSALQEQKELCQNLGERVKELEKMLEETKCEKTEIINRLTRSLEESQKQCANLLQTGSIQEANQLRFQLQQAQSAHTISNDLNKALQEELRELKEEITLYESAAKLGVFLNDAGGELHTNLSDSCVDLGIKKVSKNNSRFCSIIQNRDKDKELSKDEIIVELKAELERLLSSNKMKRNQITQLQNDLKDCQKKLEEFKQLLKAEKASKESEPVTNQNDALVASPLVSDNLKEEVLRLRKANEALLREVQNHALTIEELKENEKKLRSSNQDLCCQMRKMVQEFDEDKQEAIDRCERTYQQHHEDTKAQFEKDMMQRYAAEKQQLIQSYEETVLQLKATIEELNREMTTVKECYIAVCGEKDTLETTLRQTFAHEQQMKEDKLKKQLIEEKEESLKILRSELEERYNNSITEAKRQWEKEKEVHIAKEVAFAKVQWEKEEKEKKEDVIAKIERQWQNRLEEIKKTMFECKDCSSQTDRVTCVSDASTEELARIVEDQKLQIQKALKEKKASEEALKELEIELESKYRKRLASQVEAALTQAHARSLQELTDLKEYELALAFSSDELKWKKERECTEQSGSIIRELEEKVVSLKKELELKEEEIPVTIKAAVAKARAQWNKEKQEEIAQIQEQNERDYRSFLDDHRNKIKEVLATTKEDLAKQVNDLSAQKEAEMKMILDQKQREWEAQETKRLQDEINRYEEKTLIELECLLREVHEELVKSTYSQHSWEERDPDASVELNHQRKDKLKACLQKAYRRTVHKILEKHEQEWKEKNEELLNNANKEVCCCMQGGDGETGDMARSPLYNTGQQAETQRRLRRRHRSGTDGVEQGAKKDLWSQEVLCCKHCSQELEKKETVCQDLKRELETARKRLHLSVREQRAMSEQVQGKDENKKLVESLIAENTEMKARLKDVGTSPRLQSKGSVSKACSSCGSVKGLEEMRAQYIKSVSKIKSDMLCYIRESKERAAAMIKAEVLRERQETARKMRKYYLTCLQQLLTDNGKQEGAEKKIMNAASKLVTMAKGLETPLRHTLQCRTTRSALLLNSDLPTGVEYAKRDCLSQTRPNHMENKSCGKNTTEEANDKVVRKYVPRDLRQQFGARQTETQHMLHETDTSDIQNSNICKHLVSAGIDGLSKILPNVDGRKEKYSPLVNLDKELLCATSNFVHPNVPPFACQGQLENIDAARLKNGPAISGSTHHMLKSKNERTTLKVDKCILSHGTWQTTYERIQDFDFHRTPERDEGSCSEWSSASGSLHLDGSDKSAVYPEEKPSTNEQRQSVYCEESFSAGDENFGTSWRELTNGNVKNFNVKNSPIVYNRDELRSHSDHISSLGPDKTNSANTRTNTLPI", "length": 1760, "header": "tr|A0A8V0ZMG6-1|A0A8V0ZMG6_CHICK Isoform 1 of Centrosomal protein 152 OS=Gallus gallus OX=9031 GN=CEP152 PE=4 SV=1 CANONICAL=A0A8V0ZMG6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6/entry#A0A8V0ZGB5-1", "sequence": { "sequence": "MSLDFDSGALQTQHEDEDYDQEDYAREQELQQLLTDLPHDMLEDSGDQLSNYSDSSIHETEEQSQEARKPDGRWNDHLLINDAQNGYEQGQNLYPDQFLCDQQNDHVEKHAKNWNGLHSSEQMKHLYDVKEDYSGQNSQEDPDDIYLDRDGFNAPGCYQQSNLYHLPENFRPYTNGHNPEFNSQQNQIINFPDAPKEHLKQPFVTSEVVSGQSAESYKVMYKPYQNDVHKKIPVTQEGMRRNEVFEDLHHEFSGNDENSSENMQILQLKALNKARERRVEELNEKLEKSAQQIRYLSHQLSMVTDEKDGLAVSLHESQKLYQNGKEREVYLEGQIKALETQIQTLTTNEEQILKQSRVAEVAMESMQKQLLELQRSDTLQRAREQHDAIVTALKQKHEKQVVSLEQKLDATKSALQEQKELCQNLGERVKELEKMLEETKCEKTEIINRLTRSLEESQKQCANLLQTGSIQEANQLRFQLQQAQSAHTISNDLNKALQEELRELKEEITLYESAAKLGVFLNDAGGELHTNLSDSCVDLGIKKVSKNNSRFCSIIQNRDKDKELSKDEIIVELKAELERLLSSNKMKRNQITQLQNDLKDCQKKLEEFKQLLKAEKASKESEPVTNQNDALVASPLVSDNLKEEVLRLRKANEALLREVQNHALTIEELKENEKKLRSSNQDLCCQMRKMVQEFDEDKQEAIDRCERTYQQHHEDTKAQFEKDMMQRYAAEKQQLIQSYEETVLQLKATIEELNREMTTVKECYIAVCGEKDTLETTLRQTFAHEQQMKEDKLKKQLIEEKEESLKILRSELEERYNNSITEAKRQWEKEKEVHIAKEVAFAKVQWEKEEKEKKEDVIAKIERQWQNRLEEIKKTMFECKDCSSQTDRVTCVSDASTEELARIVEDQKLQIQKALKEKKASEEALKELEIELESKYRKRLASQVEAALTQAHARSLQELTDLKEYELALAFSSDELKWKKERECTEQSGSIIRELEEKVVSLKKELELKEEEIPVTIKAAVAKARAQWNKEKQEEIAQIQEQNERDYRSFLDDHRNKIKEVLATTKEDLAKQVNDLSAQKEAEMKMILDQKQREWEAQETKRLQDEINRYEEKTLIELECLLREVHEELVKSTYSQHSWEERDPDASVELNHQRKDKLKACLQKAYRRTVHKILEKHEQEWKEKNEELLNNANKEVCCCMQGGDGETGDMARSPLYNTGQQAETQRRLRRRHRSGTDGENKKLVESLIAENTEMKARLKDVGTSPRLQSKGSVSKACSSCGSVKGLEEMRAQYIKSVSKIKKLSLMKCVPVGDMLCYIRESKERAAAMIKAEVLRERQETARKMRKYYLTCLQQLLTDNGKQEGAEKKIMNAASKLVTMAKGLETPLRHTLQCRTTRSALLLNSDLPTGVEYAKRDCLSQTRPNHMENKSCGKNTTEEANDKVVRKYVPRDLRQQFGARQTETQHMLHETDTSDIQNSNICKHLVSAGIDGLSKILPNVDGRKEKYSPLVNLDKELLCATSNFVHPNVPPFACQGQLENIDAARLKNGPAISGSTHHMLKSKNERTTLKVDKCILSHGTWQTTYERIQDFDFHRTPERDEGSCSEWSSASGSLHLDGSDKSAVYPEEKPSTNEQRQSVYCEESFSAGDENFGTSWRELTNGNVKNFNVKNSPIVYNRDELRSHSDHISSLGPDKTNSANTRTNTLPI", "length": 1707, "header": "tr|A0A8V0ZGB5-1|A0A8V0ZMG6_CHICK Computationally mapped isoform of Centrosomal protein 152 OS=Gallus gallus OX=9031 GN=CEP152 PE=4 SV=1 CANONICAL=A0A8V0ZMG6-1" }, "locus": { "chromosome": "10", "start_pos": 10391422, "end_pos": 10370474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050604.1", "url": "https://www.ensembl.org/id/ENSGALT00010050604.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029872.1", "url": "https://www.ensembl.org/id/ENSGALP00010029872.1" } ] } }, { "isoform_ac": "A0A8V0ZGC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6/entry#A0A8V0ZGC0-1", "sequence": { "sequence": "MSLDFDSGALQTQHEDEDYDQEDYAREQELQQLLTDLPHDMLEDSGDQLSNYSDSSIHETEEQSQEARKPDGRWNDHLLINDAQNGYEQGQNLYPDQFLCDQQNDHVEKHAKNWNGLHSSEQMKHLYDVKEDYSGQNSQEDPDDIYLDRDGFNAPGCYQQSNLYHLPENFRPYTNGHNPEFNSQQNQIINFPDAPKEHLKQPFVTSEVVSGQSAESYKVMYKPYQNDVHKKIPVTQEGMRRNEVFEDLHHEFSGNDENSSENMQILQLKALNKARERRVEELNEKLEKSAQQIRYLSHQLSMVTDEKDGLAVSLHESQKLYQNGKEREVYLEGQIKALETQIQTLTTNEEQILKQSRVAEVAMESMQKQLLELQRSDTLQRAREQHDAIVTALKQKHEKQVVSLEQKLDATKSALQEQKELCQNLGERVKELEKMLEETKCEKTEIINRLTRSLEESQKQCANLLQTGSIQEANQLRFQLQQAQSAHTISNDLNKALQEELRELKEEITLYESAAKLGVFLNDAGGELHTNLSDSCVDLGIKKVSKNNSRFCSIIQNRDKDKELSKDEIIVELKAELERLLSSNKMKRNQITQLQNDLKDCQKKLEEFKQLLKAEKASKESEPVTNQNDALVASPLVSDNLKEEVLRLRKANEALLREVQNHALTIEELKENEKKLRSSNQDLCCQMRKMVQEFDEDKQEAIDRCERTYQQHHEDTKAQFEKDMMQRYAAEKQQLIQSYEETVLQLKATIEELNREMTTVKECYIAVCGEKDTLETTLRQTFAHEQQMKEDKKKEDVIAKIERQWQNRLEEIKKTMFECKDCSSQTDRVTCVSDASTEELARIVEDQKLQIQKALKEKKASEEALKELEIELESKYRKRLASQVEAALTQAHARSLQELTDLKEYELALAFSSDELKWKKERECTEQSGSIIRELEEKVVSLKKELELKEEEIPVTIKAAVAKARAQWNKEKQEEIAQIQEQNERDYRSFLDDHRNKIKEVLATTKEDLAKQVNDLSAQKEAEMKMILDQKQREWEAQETKRLQDEINRYEEKTLIELECLLREVHEELVKSTYSQHSWEERDPDASVELNHQRKDKLKACLQKAYRRTVHKILEKHEQEWKEKNEELLNNANKEVCCCMQGGDGETGDMARSPLYNTGQQAETQRRLRRRHRSGTDGVEQGAKKDLWSQEVLCCKHCSQELEKKETVCQDLKRELETARKRLHLSVREQRAMSEQVQENKKLVESLIAENTEMKARLKDVGTSPRLQSKGSVSKACSSCGSVKGLEEMRAQYIKSVSKIKSDMLCYIRESKERAAAMIKAEVLRERQETARKMRKYYLTCLQQLLTDNGKQEGAEKKIMNAASKLVTMAKGLETPLRHTLQCRTTRSALLLNSDLPTGVEYAKRDCLSQTRPNHMENKSCGKNTTEEANDKVVRKYVPRDLRQQFGARQTETQHMLHETDTSDIQNSNICKHLVSAGIDGLSKILPNVDGRKEKYSPLVNLDKELLCATSNFVHPNVPPFACQGQLENIDAARLKNGPAISGSTHHMLKSKNERTTLKVDKCILSHGTWQTTYERIQDFDFHRTPERDEGSCSEWSSASGSLHLDGSDKSAVYPEEKPSTNEQRQSVYCEESFSAGDENFGTSWRELTNGNVKNFNVKNSPIVYNRDELRSHSDHISSLGPDKTNSANTRTNTLPI", "length": 1697, "header": "tr|A0A8V0ZGC0-1|A0A8V0ZMG6_CHICK Computationally mapped isoform of Centrosomal protein 152 OS=Gallus gallus OX=9031 GN=CEP152 PE=4 SV=1 CANONICAL=A0A8V0ZMG6-1" }, "locus": { "chromosome": "10", "start_pos": 10391422, "end_pos": 10370474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050609.1", "url": "https://www.ensembl.org/id/ENSGALT00010050609.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029877.1", "url": "https://www.ensembl.org/id/ENSGALP00010029877.1" } ] } }, { "isoform_ac": "A0A8V0ZMG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6/entry#A0A8V0ZMG6-1", "sequence": { "sequence": "MSLDFDSGALQTQHEDEDYDQEDYAREQELQQLLTDLPHDMLEDSGDQLSNYSDSSIHETEEQSQEARKPDGRWNDHLLINDAQNGYEQGQNLYPDQFLCDQQNDHVEKHAKNWNGLHSSEQMKHLYDVKEDYSGQNSQEDPDDIYLDRDGFNAPGCYQQSNLYHLPENFRPYTNGHNPEFNSQQNQIINFPDAPKEHLKQPFVTSEVVSGQSAESYKVMYKPYQNDVHKKIPVTQEGMRRNEVFEDLHHEFSGNDENSSENMQILQLKALNKARERRVEELNEKLEKSAQQIRYLSHQLSMVTDEKDGLAVSLHESQKLYQNGKEREVYLEGQIKALETQIQTLTTNEEQILKQSRVAEVAMESMQKQLLELQRSDTLQRAREQHDAIVTALKQKHEKQVVSLEQKLDATKSALQEQKELCQNLGERVKELEKMLEETKCEKTEIINRLTRSLEESQKQCANLLQTGSIQEANQLRFQLQQAQSAHTISNDLNKALQEELRELKEEITLYESAAKLGVFLNDAGGELHTNLSDSCVDLGIKKVSKNNSRFCSIIQNRDKDKELSKDEIIVELKAELERLLSSNKMKRNQITQLQNDLKDCQKKLEEFKQLLKAEKASKESEPVTNQNDALVASPLVSDNLKEEVLRLRKANEALLREVQNHALTIEELKENEKKLRSSNQDLCCQMRKMVQEFDEDKQEAIDRCERTYQQHHEDTKAQFEKDMMQRYAAEKQQLIQSYEETVLQLKATIEELNREMTTVKECYIAVCGEKDTLETTLRQTFAHEQQMKEDKLKKQLIEEKEESLKILRSELEERYNNSITEAKRQWEKEKEVHIAKEVAFAKVQWEKEEKEKKEDVIAKIERQWQNRLEEIKKTMFECKDCSSQTDRVTCVSDASTEELARIVEDQKLQIQKALKEKKASEEALKELEIELESKYRKRLASQVEAALTQAHARSLQELTDLKEYELALAFSSDELKWKKERECTEQSGSIIRELEEKVVSLKKELELKEEEIPVTIKAAVAKARAQWNKEKQEEIAQIQEQNERDYRSFLDDHRNKIKEVLATTKEDLAKQVNDLSAQKEAEMKMILDQKQREWEAQETKRLQDEINRYEEKTLIELECLLREVHEELVKSTYSQHSWEERDPDASVELNHQRKDKLKACLQKAYRRTVHKILEKHEQEWKEKNEELLNNANKEVCCCMQGGDGETGDMARSPLYNTGQQAETQRRLRRRHRSGTDGVEQGAKKDLWSQEVLCCKHCSQELEKKETVCQDLKRELETARKRLHLSVREQRAMSEQVQGKDENKKLVESLIAENTEMKARLKDVGTSPRLQSKGSVSKACSSCGSVKGLEEMRAQYIKSVSKIKSDMLCYIRESKERAAAMIKAEVLRERQETARKMRKYYLTCLQQLLTDNGKQEGAEKKIMNAASKLVTMAKGLETPLRHTLQCRTTRSALLLNSDLPTGVEYAKRDCLSQTRPNHMENKSCGKNTTEEANDKVVRKYVPRDLRQQFGARQTETQHMLHETDTSDIQNSNICKHLVSAGIDGLSKILPNVDGRKEKYSPLVNLDKELLCATSNFVHPNVPPFACQGQLENIDAARLKNGPAISGSTHHMLKSKNERTTLKVDKCILSHGTWQTTYERIQDFDFHRTPERDEGSCSEWSSASGSLHLDGSDKSAVYPEEKPSTNEQRQSVYCEESFSAGDENFGTSWRELTNGNVKNFNVKNSPIVYNRDELRSHSDHISSLGPDKTNSANTRTNTLPI", "length": 1760, "header": "tr|A0A8V0ZMG6-1|A0A8V0ZMG6_CHICK Isoform 1 of Centrosomal protein 152 OS=Gallus gallus OX=9031 GN=CEP152 PE=4 SV=1 CANONICAL=A0A8V0ZMG6-1" }, "locus": { "chromosome": "10", "start_pos": 10391422, "end_pos": 10370474, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050599.1", "url": "https://www.ensembl.org/id/ENSGALT00010050599.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029869.1", "url": "https://www.ensembl.org/id/ENSGALP00010029869.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-GGA-380259", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380259", "resource": "Reactome", "description": "Loss of Nlp from mitotic centrosomes" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380284", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380284", "resource": "Reactome", "description": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" }, { "id": "R-GGA-5620912", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620912", "resource": "Reactome", "description": "Anchoring of the basal body to the plasma membrane" }, { "id": "R-GGA-8854518", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8854518", "resource": "Reactome", "description": "AURKA Activation by TPX2" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMG6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1481, "end_pos": 1483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1487, "end_pos": 1489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" }, { "start_pos": 817, "end_pos": 819, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG6" }, { "id": "PF25770", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25770" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CEP152 CEP63 binding coiled coil", "eco_id": "ECO_0000259", "start_pos": 1349, "end_pos": 1399, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1481, "end_pos": 1483 }, { "start_pos": 1487, "end_pos": 1489 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 547, "end_pos": 549 }, { "start_pos": 817, "end_pos": 819 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLP7-1", "uniprot_ac": "A0A8V0ZLP7", "uniprot_id": "A0A8V0ZLP7_CHICK", "mass": { "chemical_mass": 55543.0, "monoisotopic_mass": 55543.0 }, "refseq": { "ac": "XP_004942721", "name": "abl interactor 2 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942721" }, "gene_names": [ { "name": "ABI2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7" } ] }, { "name": "ABI2", "type": "synonym", "evidence": [ { "id": "XP_004942721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942721" } ] } ], "protein_names": [ { "name": "Abl interactor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7/entry#names_and_taxonomy" } ] }, { "name": "abl interactor 2 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_004942721", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942721" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004942721.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942721" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7", "locus": { "chromosome": "7", "start_pos": 13197839, "end_pos": 13268094, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022079", "url": "https://www.ensembl.org/id/ENSGALG00010022079" } ] } } ], "crossref": [ { "id": "A0A8V0ZLP7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLP7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11972", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11972", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424108", "url": "https://www.ncbi.nlm.nih.gov/gene/424108", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035726", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035726", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YCEGNYF", "url": "https://omabrowser.org/oma/group/YCEGNYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGD8", "url": "https://www.orthodb.org/?gene=A0A8V0ZGD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLP0", "url": "https://www.orthodb.org/?gene=A0A8V0ZLP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLP7", "url": "https://www.orthodb.org/?gene=A0A8V0ZLP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNG0", "url": "https://www.orthodb.org/?gene=A0A8V0ZNG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU46", "url": "https://www.orthodb.org/?gene=A0A8V0ZU46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10460", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10460", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10460:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10460:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27594", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27594", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2029482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4420097", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5663213", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663213", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004942721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942721", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAELQMLLEEEIPGGRRALFDSYTNLERVAEYCETNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKWLLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTIGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVYPAPAGSAGTSPLPSTSAPAPTPPAPAPSSSTPDAAAAAGAQPLADGFTSPTPPAVSSTASTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQINGGPFYNQNPVSDTPPPPPPVDEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRTYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE", "length": 512, "header": "tr|A0A8V0ZLP7-1|A0A8V0ZLP7_CHICK Isoform 1 of Abl interactor 2 OS=Gallus gallus OX=9031 GN=ABI2 PE=1 SV=1 CANONICAL=A0A8V0ZLP7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7/entry#A0A8V0ZGD8-1", "sequence": { "sequence": "MAELQMLLEEEIPGGRRALFDSYTNLERVAEYCETNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTIGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVYPGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQINGGPFYNQNPASLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVDEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRTYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDEYIKRWNRNYWSVP", "length": 462, "header": "tr|A0A8V0ZGD8-1|A0A8V0ZLP7_CHICK Computationally mapped isoform of Abl interactor 2 OS=Gallus gallus OX=9031 GN=ABI2 PE=1 SV=1 CANONICAL=A0A8V0ZLP7-1" }, "locus": { "chromosome": "7", "start_pos": 13268015, "end_pos": 13198232, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053774.1", "url": "https://www.ensembl.org/id/ENSGALT00010053774.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032377.1", "url": "https://www.ensembl.org/id/ENSGALP00010032377.1" } ] } }, { "isoform_ac": "A0A8V0ZLP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7/entry#A0A8V0ZLP0-1", "sequence": { "sequence": "MAELQMLLEEEIPGGRRALFDSYTNLERVAEYCETNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTIGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVYPAPAGSAGTSPLPSTSAPAPTPPAPAPSSSTPDAAAAAGAQPLADGFTSPTPPAVSSTASTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQINGGPFYNQNPASLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVDEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRTYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE", "length": 535, "header": "tr|A0A8V0ZLP0-1|A0A8V0ZLP0_CHICK Computationally mapped isoform of Abl interactor 2 OS=Gallus gallus OX=9031 GN=ABI2 PE=1 SV=1 CANONICAL=A0A8V0ZLP7-1" }, "locus": { "chromosome": "7", "start_pos": 13268015, "end_pos": 13217082, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053749.1", "url": "https://www.ensembl.org/id/ENSGALT00010053749.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032364.1", "url": "https://www.ensembl.org/id/ENSGALP00010032364.1" } ] } }, { "isoform_ac": "A0A8V0ZLP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7/entry#A0A8V0ZLP7-1", "sequence": { "sequence": "MAELQMLLEEEIPGGRRALFDSYTNLERVAEYCETNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKWLLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTIGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVYPAPAGSAGTSPLPSTSAPAPTPPAPAPSSSTPDAAAAAGAQPLADGFTSPTPPAVSSTASTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQINGGPFYNQNPVSDTPPPPPPVDEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRTYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE", "length": 512, "header": "tr|A0A8V0ZLP7-1|A0A8V0ZLP7_CHICK Isoform 1 of Abl interactor 2 OS=Gallus gallus OX=9031 GN=ABI2 PE=1 SV=1 CANONICAL=A0A8V0ZLP7-1" }, "locus": { "chromosome": "7", "start_pos": 13268015, "end_pos": 13217082, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053758.1", "url": "https://www.ensembl.org/id/ENSGALT00010053758.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032369.1", "url": "https://www.ensembl.org/id/ENSGALP00010032369.1" } ] } }, { "isoform_ac": "A0A8V0ZNG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7/entry#A0A8V0ZNG0-1", "sequence": { "sequence": "MAELQMLLEEEIPGGRRALFDSYTNLERVAEYCETNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKWLLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTIGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVYPAPAGSAGTSPLPSTSAPAPTPPAPAPSSSTPDAAAAAGAQPLADGFTSPTPPAVSSTASTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQINGGPFYNQNPASLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVDEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRTYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE", "length": 541, "header": "tr|A0A8V0ZNG0-1|A0A8V0ZNG0_CHICK Computationally mapped isoform of Abl interactor 2 OS=Gallus gallus OX=9031 GN=ABI2 PE=1 SV=1 CANONICAL=A0A8V0ZLP7-1" }, "locus": { "chromosome": "7", "start_pos": 13268015, "end_pos": 13217082, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053726.1", "url": "https://www.ensembl.org/id/ENSGALT00010053726.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032356.1", "url": "https://www.ensembl.org/id/ENSGALP00010032356.1" } ] } }, { "isoform_ac": "A0A8V0ZU46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7/entry#A0A8V0ZU46-1", "sequence": { "sequence": "MAELQMLLEEEIPGGRRALFDSYTNLERVAEYCETNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKWLLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTIGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVYPGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQINGGPFYNQNPASLAPPPPSILQVTPQLPLMGFVARVQENISDTPPPPPPVDEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRTYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE", "length": 481, "header": "tr|A0A8V0ZU46-1|A0A8V0ZLP7_CHICK Computationally mapped isoform of Abl interactor 2 OS=Gallus gallus OX=9031 GN=ABI2 PE=1 SV=1 CANONICAL=A0A8V0ZLP7-1" }, "locus": { "chromosome": "7", "start_pos": 13268015, "end_pos": 13217082, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053766.1", "url": "https://www.ensembl.org/id/ENSGALT00010053766.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032373.1", "url": "https://www.ensembl.org/id/ENSGALP00010032373.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 303, "start_aa": "Thr", "end_pos": 303, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr303", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 313, "start_aa": "Thr", "end_pos": 313, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr313", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-2029482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2029482", "resource": "Reactome", "description": "Regulation of actin dynamics for phagocytic cup formation" }, { "id": "R-GGA-4420097", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4420097", "resource": "Reactome", "description": "VEGFA-VEGFR2 Pathway" }, { "id": "R-GGA-5663213", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5663213", "resource": "Reactome", "description": "RHO GTPases Activate WASPs and WAVEs" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4K774-1", "protein_name": "Abelson interacting protein, isoform D", "gene_name": "Abi", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLTETPMASENIMDELASLIRTEIPDGRQSLRDSYTNLERVADYCEDTYYRADNKKAALEATKNYTTQSLASVAYQINTLAYSYMQLLELQAQQLGEMESQMNHIAQTVHIHKEKVARREIGVLTANKVSSRQFKIVAPINPEKPIKYVRKPIDYSMLDEIGHGINSAQHSQVRQKHRGSSHGSVQSLLPPSVGPPPTTKPPTPPQMSRAGNTGTLGKSVSNTGTLGKSSREYRTPPVVNPPQVPSHYAPNYPIGHPKRMSTASSTMTTTTTGGGAAGNERAAGYSALPMPPSQQIATHVNLPSAGMMQSLPPPPPTTYDDRSSMPPAPPSPLTVSQHEMTEQSHIGMHTLGRNINRNPNRNHFSLNFARPGSQSPPLPPPPPPEDEHQDFGRPRTSTGPQLAPIVPEDQNLPGWVPKNFIEKVVAIYDYYADKDDELSFQESSVLYVLKKNDDGWWEGVMDGVTGLFPGNYVEPCV", "length": 477 }, "evidence": [ { "id": "A0A8V0ZLP7", "url": "https://omabrowser.org/oma/group/A0A8V0ZLP7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0ABK0L5F0-1", "protein_name": "Abl-interactor 2", "gene_name": "Abi2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSPDKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKWLLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTLGSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPLPATSASVPTPLVPATVPSSTAPDAAAGGAQTLADGFTSPTPPVISSNPPTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYNQNPVSLAPPPPILQVTPQLPLMGFVARVQENISDTPPPPPPVDEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDESVTLDAHCLCFGANLMAWWTPLPFTFSIWRGRNQCLNTLFNYFWIA", "length": 512 }, "evidence": [ { "id": "A0A8V0ZLP7", "url": "https://omabrowser.org/oma/group/A0A8V0ZLP7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NYB9-1", "protein_name": "Abl interactor 2", "gene_name": "ABI2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKWLLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPLPATSASAPAPLVPATVPSSTAPNAAAGGAPNLADGFTSPTPPVVSSTPPTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE", "length": 513 }, "evidence": [ { "id": "A0A8V0ZLP7", "url": "https://omabrowser.org/oma/group/A0A8V0ZLP7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLP7", "url": 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}, { "name": "SCAR complex", "id": "GO:0031209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7" } ], "pmid": "" }, { "name": "actin-based cell projection", "id": "GO:0098858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098858", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7" } ], "pmid": "" }, { "name": "cell projection morphogenesis", "id": "GO:0048858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048858", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLP7" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLS7-1", "uniprot_ac": "A0A8V0ZLS7", "uniprot_id": "A0A8V0ZLS7_CHICK", "mass": { "chemical_mass": 32402.0, "monoisotopic_mass": 32402.0 }, "refseq": {}, "gene_names": [ { "name": "LOC424109", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLS7", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/ARBA00058347#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC424109", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS7", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZLS7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR005320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGF8", "url": "https://www.orthodb.org/?gene=A0A8V0ZGF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLS7", "url": "https://www.orthodb.org/?gene=A0A8V0ZLS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20842", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20842", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20842:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20842:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03575", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03575", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZGF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRKVTAKIAKSSMAGPGRSGRRERQRQLGPTPRPRGGAGRGGPGREHEQAWAAHGACCWSPTPPCTEGGTWATASSTSRASSGSKKVKRVLFVPYALHDRDAYARTAREKFASLGYELDSIHESCDPVEAVRKSEAIFIGGGNTFRLLKALYDNRLIQEIRKRVLEDGIPYMGSSAGTNVATVSINTTNDMPIVYPPSLQALGLVPFNINPHYLDPDVKSTHMGETREERIRQYHEEPNTPPVLGLREGAMLLVEGNKATLQGVTGARLFLRGKKPTEHEPGTDFSFLLMDSNFQ", "length": 296, "header": "tr|A0A8V0ZLS7-1|A0A8V0ZLS7_CHICK Isoform 1 of dipeptidase E OS=Gallus gallus OX=9031 GN=LOC424109 PE=1 SV=1 CANONICAL=A0A8V0ZLS7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS7/entry#A0A8V0ZGF8-1", "sequence": { "sequence": "MGCPRRLLLVSNSTMHGGGYLGHCQQHIQSFLGEKVKRVLFVPYALHDRDAYARTAREKFASLGYELDSIHESCDPVEAVRKSEAIFIGGGNTFRLLKALYDNRLIQEIRKRVLEETREERIRQYHEEPNTPPVLGLREGAMLLVEGNKATLQGVTGARLFLRNQLNMSLEQISVSC", "length": 177, "header": "tr|A0A8V0ZGF8-1|A0A8V0ZLS7_CHICK Computationally mapped isoform of dipeptidase E OS=Gallus gallus OX=9031 GN=LOC424109 PE=1 SV=1 CANONICAL=A0A8V0ZLS7-1" }, "locus": { "chromosome": "7", "start_pos": 13301394, "end_pos": 13295964, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053819.1", "url": "https://www.ensembl.org/id/ENSGALT00010053819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032397.1", "url": "https://www.ensembl.org/id/ENSGALP00010032397.1" } ] } }, { "isoform_ac": "A0A8V0ZLS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS7/entry#A0A8V0ZLS7-1", "sequence": { "sequence": "MSRKVTAKIAKSSMAGPGRSGRRERQRQLGPTPRPRGGAGRGGPGREHEQAWAAHGACCWSPTPPCTEGGTWATASSTSRASSGSKKVKRVLFVPYALHDRDAYARTAREKFASLGYELDSIHESCDPVEAVRKSEAIFIGGGNTFRLLKALYDNRLIQEIRKRVLEDGIPYMGSSAGTNVATVSINTTNDMPIVYPPSLQALGLVPFNINPHYLDPDVKSTHMGETREERIRQYHEEPNTPPVLGLREGAMLLVEGNKATLQGVTGARLFLRGKKPTEHEPGTDFSFLLMDSNFQ", "length": 296, "header": "tr|A0A8V0ZLS7-1|A0A8V0ZLS7_CHICK Isoform 1 of dipeptidase E OS=Gallus gallus OX=9031 GN=LOC424109 PE=1 SV=1 CANONICAL=A0A8V0ZLS7-1" }, "locus": { "chromosome": "7", "start_pos": 13301414, "end_pos": 13295812, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053822.1", "url": "https://www.ensembl.org/id/ENSGALT00010053822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032399.1", "url": "https://www.ensembl.org/id/ENSGALP00010032399.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 32, "start_aa": "Thr", "end_pos": 32, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr32", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 63, "start_aa": "Thr", "end_pos": 63, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr63", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS7" } ], "pmid": "" }, { "name": "dipeptidase activity", "id": "GO:0016805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.13.21", "ec_name": "Dipeptidase E catalyzes the hydrolysis of dipeptides Asp-|-Xaa. It does not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave isoaspartyl peptides.", "evidence": [] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 32, 63 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMH9-1", "uniprot_ac": "A0A8V0ZMH9", "uniprot_id": "A0A8V0ZMH9_CHICK", "mass": { "chemical_mass": 160490.0, "monoisotopic_mass": 160490.0 }, "refseq": { "ac": "XP_004944685", "name": "ubiquitin carboxyl-terminal hydrolase 19 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944685" }, "gene_names": [ { "name": "USP19", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ] }, { "name": "USP19", "type": "synonym", "evidence": [ { "id": "XP_004944685", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944685" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase 19", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9/entry#names_and_taxonomy" } ] }, { "name": "Deubiquitinating enzyme 19", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin thioesterase 19", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin-specific-processing protease 19", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 19 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004944685", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944685" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004944685.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944685", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944685" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USP19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9", "locus": { "chromosome": "12", "start_pos": 11772931, "end_pos": 11753372, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022242", "url": "https://www.ensembl.org/id/ENSGALG00010022242" } ] } } ], "crossref": [ { "id": "cd02674", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02674", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06463", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06463", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06466", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06466", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858727", "url": "https://www.ncbi.nlm.nih.gov/gene/100858727", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RIWPQRV", "url": "https://omabrowser.org/oma/group/RIWPQRV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH59", "url": "https://www.orthodb.org/?gene=A0A8V0ZH59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMH9", "url": "https://www.orthodb.org/?gene=A0A8V0ZMH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPC5", "url": "https://www.orthodb.org/?gene=A0A8V0ZPC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPU3", "url": "https://www.orthodb.org/?gene=A0A8V0ZPU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21646:SF74", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21646:SF74", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004944685", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944685", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSTNAPGQRRVSRGLDDATNKKKQKDRANQESKEVSRPELEQAETSQERDLEEELLLDWKQNADEIIVKLNLGSGSLKVEDVDTFFTDTDCVIKLPDGRQWSCQFYEEIEGSCSKIQCKKGNFLQLVLQKKIPLHTWSSLLKRKKDGSKELGKGATCWENGKEKASSAELAPEEPRTESSELPRTRREPSNPKRAQGRSEALGGKSPASPGTQSGPSAKRAVYLKVAPAEEEPNTRVTGSVEPSKGHGGRSGSRRNGRASQGDVPTALTDLAPPLEKAVIMAKETVPVEMPPLAATTEVFPHRVATCVEKRVLQPGSPVEASRGRESAPVLGESSKAIPSATRPLGRDGEKRDWSKDDVALEAAADEPEPFVSLTFVKNDSYEKGNDLVVVHVYVKEIHKETSKVFFREQDFTLVFQTSDINFLRLHPGCGPHTVFRWQVKLRNLIEPDQCTYNFTASRIDVCLKKRHSQRWGGLEAPATRGAVGGAKVAMPTGPTPLDKTPPGSNQHPLSSKEEARTSEKEKPRVEDGSLDGVAARTAQEHVTVKQEPHIPSPKPTCMVPPMTHSPVSAESVEDDEDEDEKKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDYFHDRSFESEINYNNPLGTGGRLAIGFAMLLRALWKGTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCSKVSITFDPFLYLPVPLPQKQKVLTVYYFAKEPHKKPIKFLVSISKENSSAMEVLDSVAHSVHVKPDNLRLAEVIKNRFQRMFLPSQSLDTVSPTDLLLCFEVLSPELAKERVVELQVQQRPQVPSVPVAKCAACQKKQLSEEEKLRRCTRCYRVGYCNVTCQKTHWPDHKALCRPENIGFPFLISVPESRLTYARLAQLLEGYARYSVSVFQPPFQLGRMSPEQGLQPLLLDKLEPLAKGSCAAATSAPELGDGDRASGLLQEPPLSPAVPELYPEMSDTGTVRSKVLAARSSLLSLDSGFSEHMDLQGDSCCEKEPSYERALKPEAAIPGYQHTPDSLSARATQFYINKIDAANKEYKLEDKGDTPLELTDDCSLALVWKNNERLKEFVLVESKELECVEDPSSASEAARAGHFTLEQCLNLFTKPEVLAPEEAWYCPKCKQHREASKQLMLWRLPNVLIIQLKRFSFRSFIWRDKINDMVDFPVRSLDLSKFCIGRKGEQQLPMYDLYAVINHYGGMIGGHYTAYARLPNDKNSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRNSPVERPLPGHPPDHRAERTPSAEAAASQASLIWQELEAEEQELQLEAPQRPARNSWRPRGQKRSPGTPQHPDEGCVKYFILATTAAIVALFLNVFYPLIYQTRWR", "length": 1434, "header": "tr|A0A8V0ZMH9-1|A0A8V0ZMH9_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 19 OS=Gallus gallus OX=9031 GN=USP19 PE=1 SV=1 CANONICAL=A0A8V0ZMH9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZH59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9/entry#A0A8V0ZH59-1", "sequence": { "sequence": "MSSSTNAPGQRRVSRGLDDATNKKKQKDRANQESKEELLLDWKQNADEIIVKLNLGSGSLKVEDVDTFFTDTDCVIKLPDGRQWSCQFYEEIEGSCSKIQCKKGNFLQLVLQKKIPLHTWSSLLKRKKDGSKELGKGATCWENGKEKASSAELAPEEPRTESSELPRTRREPSNPKRAQGRSEALGGKSPASPGTQSGPSAKRAVYLKVAPAEEEPNTRVTGSVEPSKGHGGRSGSRRNGRASQGDVPTALTDLAPPLEKAVIMAKETVPVEMPPLAATTEVFPHRVATCVEKRVLQPGSPVEASRGRESAPVLGESSKAIPSATRPLGRDGEKRDWSKDDVALEAAADEPEPFVSLTFVKNDSYEKGNDLVVVHVYVKEIHKETSKVFFREQDFTLVFQTSDINFLRLHPGCGPHTVFRWQVKLRNLIEPDQCTYNFTASRIDVCLKKRHSQRWGGLEAPATRGAVGGAKVAMPTGPTPLDKTPPGSNQHPLSSKEEARTSEKEKPRVEDGSLDGVAARTAQEHVTVKQEPHIPSPKPTCMVPPMTHSPVSAESVEDDEDEDEKKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDYFHDRSFESEINYNNPLGTGGRLAIGFAMLLRALWKGTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCSKVSITFDPFLYLPVPLPQKQKVLTVYYFAKEPHKKPIKFLVSISKENSSAMEVLDSVAHSVHVKPDNLRLAEVIKNRFQRMFLPSQSLDTVSPTDLLLCFEVLSPELAKERVVELQVQQRPQVPSVPVAKCAACQKKQLSEEEKLRRCTRCYRVGYCNVTCQKTHWPDHKALCRPENIGFPFLISVPESRLTYARLAQLLEGYARYSVSVFQPPFQLGRMSPEQGLQPLLLDKLEPLAKGSCAAATSAPELGDGDRASGLLQEPPLSPAVPELYPEMSDTGTVRSKVLAARSSLLSLDSGFSEHMDLQGDSCCEKEPSYERALKPEAAIPGYQHTPDSLSARATQFYINKIDAANKEYKLEDKGDTPLELTDDCSLALVWKNNERLKEFVLVESKELECVEDPSSASEAARAGHFTLEQCLNLFTKPEVLAPEEAWYCPKCKQHREASKQLMLWRLPNVLIIQLKRFSFRSFIWRDKINDMVDFPVRSLDLSKFCIGRKGEQQLPMYDLYAVINHYGGMIGGHYTAYARLPNDKNSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRNSPVERPLPGHPPDHRAERTPSAEAAASQHCPTR", "length": 1343, "header": "tr|A0A8V0ZH59-1|A0A8V0ZMH9_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 19 OS=Gallus gallus OX=9031 GN=USP19 PE=1 SV=1 CANONICAL=A0A8V0ZMH9-1" }, "locus": { "chromosome": "12", "start_pos": 11769799, "end_pos": 11756306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054118.1", "url": "https://www.ensembl.org/id/ENSGALT00010054118.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032649.1", "url": "https://www.ensembl.org/id/ENSGALP00010032649.1" } ] } }, { "isoform_ac": "A0A8V0ZMH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9/entry#A0A8V0ZMH9-1", "sequence": { "sequence": "MSSSTNAPGQRRVSRGLDDATNKKKQKDRANQESKEVSRPELEQAETSQERDLEEELLLDWKQNADEIIVKLNLGSGSLKVEDVDTFFTDTDCVIKLPDGRQWSCQFYEEIEGSCSKIQCKKGNFLQLVLQKKIPLHTWSSLLKRKKDGSKELGKGATCWENGKEKASSAELAPEEPRTESSELPRTRREPSNPKRAQGRSEALGGKSPASPGTQSGPSAKRAVYLKVAPAEEEPNTRVTGSVEPSKGHGGRSGSRRNGRASQGDVPTALTDLAPPLEKAVIMAKETVPVEMPPLAATTEVFPHRVATCVEKRVLQPGSPVEASRGRESAPVLGESSKAIPSATRPLGRDGEKRDWSKDDVALEAAADEPEPFVSLTFVKNDSYEKGNDLVVVHVYVKEIHKETSKVFFREQDFTLVFQTSDINFLRLHPGCGPHTVFRWQVKLRNLIEPDQCTYNFTASRIDVCLKKRHSQRWGGLEAPATRGAVGGAKVAMPTGPTPLDKTPPGSNQHPLSSKEEARTSEKEKPRVEDGSLDGVAARTAQEHVTVKQEPHIPSPKPTCMVPPMTHSPVSAESVEDDEDEDEKKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDYFHDRSFESEINYNNPLGTGGRLAIGFAMLLRALWKGTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCSKVSITFDPFLYLPVPLPQKQKVLTVYYFAKEPHKKPIKFLVSISKENSSAMEVLDSVAHSVHVKPDNLRLAEVIKNRFQRMFLPSQSLDTVSPTDLLLCFEVLSPELAKERVVELQVQQRPQVPSVPVAKCAACQKKQLSEEEKLRRCTRCYRVGYCNVTCQKTHWPDHKALCRPENIGFPFLISVPESRLTYARLAQLLEGYARYSVSVFQPPFQLGRMSPEQGLQPLLLDKLEPLAKGSCAAATSAPELGDGDRASGLLQEPPLSPAVPELYPEMSDTGTVRSKVLAARSSLLSLDSGFSEHMDLQGDSCCEKEPSYERALKPEAAIPGYQHTPDSLSARATQFYINKIDAANKEYKLEDKGDTPLELTDDCSLALVWKNNERLKEFVLVESKELECVEDPSSASEAARAGHFTLEQCLNLFTKPEVLAPEEAWYCPKCKQHREASKQLMLWRLPNVLIIQLKRFSFRSFIWRDKINDMVDFPVRSLDLSKFCIGRKGEQQLPMYDLYAVINHYGGMIGGHYTAYARLPNDKNSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRNSPVERPLPGHPPDHRAERTPSAEAAASQASLIWQELEAEEQELQLEAPQRPARNSWRPRGQKRSPGTPQHPDEGCVKYFILATTAAIVALFLNVFYPLIYQTRWR", "length": 1434, "header": "tr|A0A8V0ZMH9-1|A0A8V0ZMH9_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 19 OS=Gallus gallus OX=9031 GN=USP19 PE=1 SV=1 CANONICAL=A0A8V0ZMH9-1" }, "locus": { "chromosome": "12", "start_pos": 11770622, "end_pos": 11756306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054126.1", "url": "https://www.ensembl.org/id/ENSGALT00010054126.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032657.1", "url": "https://www.ensembl.org/id/ENSGALP00010032657.1" } ] } }, { "isoform_ac": "A0A8V0ZPC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9/entry#A0A8V0ZPC5-1", "sequence": { "sequence": "MSSSTNAPGQRRVSRGLDDATNKKKQKDRANQESKEELLLDWKQNADEIIVKLNLGSGSLKVEDVDTFFTDTDCVIKLPDGRQWSCQFYEEIEGSCSKIQCKKGNFLQLVLQKKIPLHTWSSLLKRKKDGSKELGKGATCWENGKEKASSAELAPEEPRTESSELPRTRREPSNPKRAQGRSEALGGKSPASPGTQSGPSAKRAVYLKVAPAEEEPNTRVTGSVEPSKGHGGRSGSRRNGRASQGDVPTALTDLAPPLEKAVIMAKETVPVEMPPLAATTEVFPHRVATCVEKRVLQPGSPVEASRGRESAPVLGESSKAIPSATRPLGRDGEKRDWSKDDVALEAAADEPEPFVSLTFVKNDSYEKGNDLVVVHVYVKEIHKETSKVFFREQDFTLVFQTSDINFLRLHPGCGPHTVFRWQVKLRNLIEPDQCTYNFTASRIDVCLKKRHSQRWGGLEAPATRGAVGGAKVAMPTGPTPLDKTPPGSNQHPLSSKEEARTSEKEKPRVEDGSLDGVAARTAQEHVTVKQEPHIPSPKPTCMVPPMTHSPVSAESVEDDEDEDEKKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDYFHDRSFESEINYNNPLGTGGRLAIGFAMLLRALWKGTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCSKVSITFDPFLYLPVPLPQKQKVLTVYYFAKEPHKKPIKVKDTNYSGEVAREGSWRCHRQLVLCEWAERCVKPGPACLNVVLTLWQFLVSISKENSSAMEVLDSVAHSVHVKPDNLRLAEVIKNRFQRMFLPSQSLDTVSPTDLLLCFEVLSPELAKERVVELQVQQRPQVPSVPVAKCAACQKKQLSEEEKLRRCTRCYRVGYCNVTCQKTHWPDHKALCRPENIGFPFLISVPESRLTYARLAQLLEGYARYSVSVFQPPFQLGRMSPEQGLQPLLLDKLEPLAKGSCAAATSAPELGDGDRASGLLQEPPLSPAVPELYPEMSDTGTVRSKVLAARSSLLSLDSGFSEHMDLQGDSCCEKEPSYERALKPEAAIPGYQHTPDSLSARATQFYINKIDAANKEYKLEDKGDTPLELTDDCSLALVWKNNERLKEFVLVESKELECVEDPSSASEAARAGHFTLEQCLNLFTKPEVLAPEEAWYCPKCKQHREASKQLMLWRLPNVLIIQLKRFSFRSFIWRDKINDMVDFPVRSLDLSKFCIGRKGEQQLPMYDLYAVINHYGGMIGGHYTAYARLPNDKNSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRNSPVERPLPGHPPDHRAERTPSAEAAASQGLTPVPFGSGLAPEGAPPLAAEGLPERFASPAERPAPSYSSMEEVD", "length": 1431, "header": "tr|A0A8V0ZPC5-1|A0A8V0ZPC5_CHICK Computationally mapped isoform of ubiquitinyl hydrolase 1 OS=Gallus gallus OX=9031 GN=USP19 PE=1 SV=1 CANONICAL=A0A8V0ZMH9-1" }, "locus": { "chromosome": "12", "start_pos": 11772818, "end_pos": 11756306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054145.1", "url": "https://www.ensembl.org/id/ENSGALT00010054145.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032676.1", "url": "https://www.ensembl.org/id/ENSGALP00010032676.1" } ] } }, { "isoform_ac": "A0A8V0ZPU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9/entry#A0A8V0ZPU3-1", "sequence": { "sequence": "MSSSTNAPGQRRVSRGLDDATNKKKQKDRANQESKEELLLDWKQNADEIIVKLNLGSGSLKVEDVDTFFTDTDCVIKLPDGRQWSCQFYEEIEGSCSKIQCKKGNFLQLVLQKKIPLHTWSSLLKRKKDGSKELGKGATCWENGKEKASSAELAPEEPRTESSELPRTRREPSNPKRAQGRSEALGGKSPASPGTQSGPSAKRAVYLKVAPAEEEPNTRVTGSVEPSKGHGGRSGSRRNGRASQGDVPTALTDLAPPLEKAVIMAKETVPVEMPPLAATTEVFPHRVATCVEKRVLQPGSPVEASRGRESAPVLGESSKAIPSATRPLGRDGEKRDWSKDDVALEAAADEPEPFVSLTFVKNDSYEKGNDLVVVHVYVKEIHKETSKVFFREQDFTLVFQTSDINFLRLHPGCGPHTVFRWQVKLRNLIEPDQCTYNFTASRIDVCLKKRHSQRWGGLEAPATRGAVGGAKVAMPTGPTPLDKTPPGSNQHPLSSKEEARTSEKEKPRVEDGSLDGVAARTAQEHVTVKQEPHIPSPKPTCMVPPMTHSPVSAESVEDDEDEDEKKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDYFHDRSFESEINYNNPLGTGGRLAIGFAMLLRALWKGTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCSKVSITFDPFLYLPVPLPQKQKVLTVYYFAKEPHKKPIKFLVSISKENSSAMEVLDSVAHSVHVKPDNLRLAEVIKNRFQRMFLPSQSLDTVSPTDLLLCFEVLSPELAKERVVELQVQQRPQVPSVPVAKCAACQKKQLSEEEKLRRCTRCYRVGYCNVTCQKTHWPDHKALCRPENIGFPFLISVPESRLTYARLAQLLEGYARYSVSVFQPPFQLGRMSPEQGLQPLLLDKLEPLAKGSCAAATSAPELGDGDRASGLLQEPPLSPAVPELYPEMSDTGTVRSKVLAARSSLLSLDSGFSEHMDLQGDSCCEKEPSYERALKPEAAIPGYQHTPDSLSARATQFYINKIDAANKEYKLEDKGDTPLELTDDCSLALVWKNNERLKEFVLVESKELECVEDPSSASEAARAGHFTLEQCLNLFTKPEVLAPEEAWYCPKCKQHREASKQLMLWRLPNVLIIQLKRFSFRSFIWRDKINDMVDFPVRSLDLSKFCIGRKGEQQLPMYDLYAVINHYGGMIGGHYTAYARLPNDKNSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRNSPVERPLPGHPPDHRAERTPSAEAAASQASLIWQELEAEEQELQLEAPQRPARNSWRPRGQKRSPGTPQHPDEGCVKYFILATTAAIVALFLNVFYPLIYQTRWR", "length": 1415, "header": "tr|A0A8V0ZPU3-1|A0A8V0ZPU3_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 19 OS=Gallus gallus OX=9031 GN=USP19 PE=1 SV=1 CANONICAL=A0A8V0ZMH9-1" }, "locus": { "chromosome": "12", "start_pos": 11770622, "end_pos": 11756306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054139.1", "url": "https://www.ensembl.org/id/ENSGALT00010054139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032669.1", "url": "https://www.ensembl.org/id/ENSGALP00010032669.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 498, "start_aa": "Thr", "end_pos": 498, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr498", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "O94966-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 19", "gene_name": "USP19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGGASATGPRRGPPGLEDTTSKKKQKDRANQESKDGDPRKETGSRYVAQAGLEPLASGDPSASASHAAGITGSRHRTRLFFPSSSGSASTPQEEQTKEGACEDPHDLLATPTPELLLDWRQSAEEVIVKLRVGVGPLQLEDVDAAFTDTDCVVRFAGGQQWGGVFYAEIKSSCAKVQTRKGSLLHLTLPKKVPMLTWPSLLVEADEQLCIPPLNSQTCLLGSEENLAPLAGEKAVPPGNDPVSPAMVRSRNPGKDDCAKEEMAVAADAATLVDEPESMVNLAFVKNDSYEKGPDSVVVHVYVKEICRDTSRVLFREQDFTLIFQTRDGNFLRLHPGCGPHTTFRWQVKLRNLIEPEQCTFCFTASRIDICLRKRQSQRWGGLEAPAARVGGAKVAVPTGPTPLDSTPPGGAPHPLTGQEEARAVEKDKSKARSEDTGLDSVATRTPMEHVTPKPETHLASPKPTCMVPPMPHSPVSGDSVEEEEEEEKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQKQKVLPVFYFAREPHSKPIKFLVSVSKENSTASEVLDSLSQSVHVKPENLRLAEVIKNRFHRVFLPSHSLDTVSPSDTLLCFELLSSELAKERVVVLEVQQRPQVPSVPISKCAACQRKQQSEDEKLKRCTRCYRVGYCNQLCQKTHWPDHKGLCRPENIGYPFLVSVPASRLTYARLAQLLEGYARYSVSVFQPPFQPGRMALESQSPGCTTLLSTGSLEAGDSERDPIQPPELQLVTPMAEGDTGLPRVWAAPDRGPVPSTSGISSEMLASGPIEVGSLPAGERVSRPEAAVPGYQHPSEAMNAHTPQFFIYKIDSSNREQRLEDKGDTPLELGDDCSLALVWRNNERLQEFVLVASKELECAEDPGSAGEAARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRSFIWRDKINDLVEFPVRNLDLSKFCIGQKEEQLPSYDLYAVINHYGGMIGGHYTACARLPNDRSSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRNSPVERPPRAGHSEHHPDLGPAAEAAASQASRIWQELEAEEEPVPEGSGPLGPWGPQDWVGPLPRGPTTPDEGCLRYFVLGTVAALVALVLNVFYPLVSQSRWR", "length": 1318 }, "evidence": [ { "id": "A0A8V0ZMH9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMH9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UJD6-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 19", "gene_name": "Usp19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAGASATGPRRGPPGLEEATSKKKQKDRANLESKDGDARRVSLPRKEPTKDELLLDWRQSADEVIVKLRVGTGPVRLEDVDAAFTDTDCVVRLPDGRQWGGVFFAEIQSSCTKVQARKGGLLQLVLPKKVPLLTWPSLLKPLGTQELVPGLQCQENGQELSPIALEPGSEPRRAKQEARNQKRAQGRGEVGSGAGPGTQAGPSAKRAVHLRRGPEGEGSMDGPGPQGDAPSFLSDSATQVEAEEKLCAPPMNTQTSLLSSEKSLALLTVEKTVSPRNDPVAPVMVQDRDPEPEQEDQVKEEMALGADPTALVEEPESMVNLAFVKNDSYEKGPDSVVVHVYVKEIRRDSSRVLFREQDFTLIFQTRDGNFLRLHPGCGPHTIFRWQVKLRNLIEPEQCTFCFTASRIDICLRKRQSQRWGGLEAPATRGAVGGAKVAVPTGPTPLDSTPPGGGPHPLTGQEEARAVEKEKPKARSEDSGLDGVVARTPLEHVAPKPDPHLASPKPTCMVPPMPHSPVSGDSVEEDEEEEKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLLRALWKGTHQAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQKQKVLPIFYFAREPHSKPIKFLVSVSKENSSASEVLDSLSQSVHVKPENLRLAEVIKNRFHRVFLPSHSLDAVSPTDVLLCFELLSPELAKERVVVLEVQQRPQVPSIPISKCAACQRKQQSEEEKLKRCTRCYRVGYCNQFCQKTHWPDHKGLCRPENIGYPFLVSVPASRLTYARLAQLLEGYARYSVSVFQPPFQPGRMALESQSPGCTTLLSTSSLEAGDSEREPIQPSELQLVTPVAEGDTGAHRVWPPADRGPVPSTSGLSSEMLASGPIEGCPLLAGERVSRPEAAVPGYQHSSESVNTHTPQFFIYKIDASNREQRLEDKGETPLELGDDCSLALVWRNNERLQEFVLVASKELECAEDPGSAGEAARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRSFIWRDKINDLVEFPVRNLDLSKFCIGQKEEQLPSYDLYAVINHYGGMIGGHYTACARLPNDRSSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRNSPVERPPRASHSEHHPDLGPAAEAAASQASRIWQELEAEEEMVPEGPGPLGPWGPQDWVGPPPRGPTTPDEGCLRYFVLGTVAALVALVLNVFYPLVSQSRWR", "length": 1360 }, "evidence": [ { "id": "A0A8V0ZMH9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMH9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6J1Y9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 19", "gene_name": "Usp19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGTSATGPRRGPPGLEEATSKKKQKDRANQESKDGDPRRVSMPRKEPTKDELLLDWRQSSDKVVVKLRVGTGPICLEEVDAAFTDTDCVVRLPDGRQWGGVFFAKIQSSCTKVQTRKGGLLQLALPKKVPLLTWPSLLKKPLGTQELVPGLRCQENGQELSPIALEPGSEPRRAKQEARNQKRAQGRGEVGSGASPGAQAGPSAKRAVHLCRGPEGEGSMDGPGPQGDAPSFLSDSATQVEAEEQLHVPPVNPQTSLLGSEKNLALLTVEKTVSPRSDSVSPVMIRNRDPEKDDHFKEEMAVGADPAALADEPESMVNLAFVKNDSYEKGPDSVVVHVYVKESRRDTSRVLFREQDFTLIFQTRDGNFLRLHPGCGPHTIFRWQVKLRNLIEPEQCTFCFTASRIDICLRKRQSQRWGGLEAPATRVGGAKVAVPTGPTPLDSTPPGGGPLPLTGQEEARAVEKEKPKARSEDSGLDGVVARTPLEHVTPKPEPHLASPKPTCMVPPMPHSPVSGDSVEEDEEEEKKVCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLLRALWKGTHQAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQKQKVLPIYYFAREPHSKPIKFLVSVSKENSSASEVLESLSQSVHVKPESLRLAEVIKNRFHRVFLPSHSLDAVSPTDVLLCFELLSPELAKERVVVLEVQQRPQVPSIPISKCAACQRKQQSEDEKLKRCTRCYRVGYCNQFCQKTHWPDHKGLCRPENIGYPFLVSVPASRLTYARLAQLLEGYARYSVSVFQPPFQPGRMALESQSPGCTTLLSTSSLEAGDSEREPIQPSELQLVTPVAEGDTGAHRMWPPADRGPVPSTSGISSEMLASGPMEGCSLLAGERVSRPEAAVPGYQHSRESVSAHTPQFFIYKIDASSREQRLEDKGDTPLELGDDCSLALVWRNNERLQEFVLVASKELECAEDPGSAGEAARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVLIVQLKRFSFRSFIWRDKINDLVEFPVRNLDLSKFCIGQKEEQLPSYDLYAVINHYGGMIGGHYTACARLPSDRSSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRRRNSPVERPPRAAHAEHHPDLGPAAEAAASQASRIWQELEAEEEMVPEGPGPLGPWGPQDWVGPPPRGPTTSDEGCLRYFVLGTVAALVALVLNVFYPLVSQSRWR", "length": 1357 }, "evidence": [ { "id": "A0A8V0ZMH9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMH9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" }, { "name": "regulation of ERAD pathway", "id": "GO:1904292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904292", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" }, { "name": "regulation of cellular response to hypoxia", "id": "GO:1900037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 914, "end_pos": 916, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-6781797", "name": "USP19 binds HIF1A,BIRC2,BIRC3", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZMH9-1" ], "evidence": [ { "id": "R-GGA-6781797", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6781797" } ] }, { "id": "R-GGA-6781814", "name": "USP19 deubiquitinates RNF123", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A7T1-1", "A0A8V0ZMH9-1" ], "evidence": [ { "id": "R-GGA-6781814", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6781814" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZMH9", "gene_name": "USP19", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A0A8V0ZMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A0A8V0ZMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" }, { "id": "PS51203", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CS", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 143, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 887, "end_pos": 929, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZMH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH9" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 593, "end_pos": 1328, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 498 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 381, "end_pos": 383 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 734, "end_pos": 736 }, { "start_pos": 803, "end_pos": 805 }, { "start_pos": 914, "end_pos": 916 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMM0-1", "uniprot_ac": "A0A8V0ZMM0", "uniprot_id": "A0A8V0ZMM0_CHICK", "mass": { "chemical_mass": 56824.0, "monoisotopic_mass": 56824.0 }, "refseq": {}, "gene_names": [ { "name": "NOC4L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM0" } ] } ], "protein_names": [ { "name": "Nucleolar complex associated 4 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMM0", "database": "UniProtKB", "url": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027193", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027193", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHA0", "url": "https://www.orthodb.org/?gene=A0A8V0ZHA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMM0", "url": "https://www.orthodb.org/?gene=A0A8V0ZMM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12455", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12455", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12455:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12455:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03914", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03914", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZHA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARPALAASLEAVLGDRGNANRVFEILELLAAKEEEDVLCAARTCRRLFAALLRRGELFAGSLPAEEDALRGNYSAEEKYKIWMRHRYNDCVESLSELLGHDSFQVKESSLCTLMKFWKGSIAFPRHLLKVVVNGLIPIHEDASLLISRFQEYMEYEDVRYFVMKAVTESIGQVMQKIKERPLPFYQQNVFSLISPINMPNKERDMVKFMMKQDNQEEWKVSKLQAHKQAFERMWLTFLKHQLPSGLYKKVLVILHDSILPYMNEPTLMIDFLTVAYGVGGAISLLALNGLFILIHQHNLEYPDFYKKLYSLLDPSIYHVKYRARFFHLADLFLSSSHLPAYLVAAFIKRLSRLALTAPPEALLMVIPFICNLFRRHPACKVLMHRPNGPQDLSEDPYIMEQEEPSESRALESSLWELQSLQNHYHPDVAQAAAILNQSLSEIEDDISGLLELSASELFDKEIKKTSANVPLEFEQVRGLFGKKNDIIAEHFALD", "length": 495, "header": "tr|A0A8V0ZMM0-1|A0A8V0ZMM0_CHICK Isoform 1 of Nucleolar complex associated 4 homolog OS=Gallus gallus OX=9031 GN=NOC4L PE=3 SV=1 CANONICAL=A0A8V0ZMM0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM0/entry#A0A8V0ZHA0-1", "sequence": { "sequence": "MARPALAASLEAVLGDRGNANRVFEILELLAAKEEEDVLCAARTCRRLFAALLRRGELFAGSLPAEEDALRGNYSAEEKYKIWMRHRYNDCVESLSELLGHDSFQVKVVVNGLIPIHEDASLLISRFQEYMEYEDVRYFVMKAVTESIGQVMQKIKERPLPFYQQNVFSLISPINMPNKERDMVKFMMKQDNQEEWKVSKLQAHKQAFERMWLTFLKHQLPSGLYKKVLVILHDSILPYMNEPTLMIDFLTVAYGVGGAISLLALNGLFILIHQHNLEYPDFYKKLYSLLDPSIYHVKYRARFFHLADLFLSSSHLPAYLVAAFIKRLSRLALTAPPEALLMVIPFICNLFRRHPACKVLMHRPNGPQDLSEDPYIMEQEEPSESRALESSLWELQSLQNHYHPDVAQAAAILNQSLSEIEDDISGLLELSASELFDKEIKKTSANVPLEFEQVRGLFGKKNDIIAEHFALD", "length": 472, "header": "tr|A0A8V0ZHA0-1|A0A8V0ZMM0_CHICK Computationally mapped isoform of Nucleolar complex associated 4 homolog OS=Gallus gallus OX=9031 GN=NOC4L PE=3 SV=1 CANONICAL=A0A8V0ZMM0-1" }, "locus": { "chromosome": "15", "start_pos": 2597905, "end_pos": 2589293, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054170.1", "url": "https://www.ensembl.org/id/ENSGALT00010054170.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032700.1", "url": 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Transcript", "id": "ENSGALT00010054179.1", "url": "https://www.ensembl.org/id/ENSGALT00010054179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032707.1", "url": "https://www.ensembl.org/id/ENSGALP00010032707.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM0" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM0" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM0" } ], "pmid": "" }, { "name": "Noc4p-Nop14p complex", "id": "GO:0030692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030692", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM0" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM0" }, { "id": "PF03914", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03914" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCAAT-binding factor", "eco_id": "ECO_0000259", "start_pos": 284, "end_pos": 433, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 437, "end_pos": 439 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMP6-1", "uniprot_ac": "A0A8V0ZMP6", "uniprot_id": "A0A8V0ZMP6_CHICK", "mass": { "chemical_mass": 51326.0, "monoisotopic_mass": 51326.0 }, "refseq": { "ac": "XP_015147920", "name": "coiled-coil domain-containing protein 91 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147920" }, "gene_names": [ { "name": "CCDC91", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6" } ] }, { "name": "CCDC91", "type": "synonym", "evidence": [ { "id": "XP_015147920", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147920" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 91", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 91 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015147920", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147920" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147920.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147920" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6", "locus": { "chromosome": "1", "start_pos": 73181666, "end_pos": 72973819, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022274", "url": "https://www.ensembl.org/id/ENSGALG00010022274" } ] } } ], "crossref": [ { "id": "A0A8V0ZMP6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "419045", "url": "https://www.ncbi.nlm.nih.gov/gene/419045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR034592", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034592", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHD8", "url": "https://www.orthodb.org/?gene=A0A8V0ZHD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMP1", "url": "https://www.orthodb.org/?gene=A0A8V0ZMP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMP6", "url": "https://www.orthodb.org/?gene=A0A8V0ZMP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPM7", "url": "https://www.orthodb.org/?gene=A0A8V0ZPM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPZ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZPZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV44", "url": "https://www.orthodb.org/?gene=A0A8V0ZV44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV78", "url": "https://www.orthodb.org/?gene=A0A8V0ZV78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV92", "url": "https://www.orthodb.org/?gene=A0A8V0ZV92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35072:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35072:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015147920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147920", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPM7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDDDFGGFEAAESYECGNGDKQMTSPAIPWAAFPTEFEVHISQNVSPDVLLEHCVPSSFLDASDSFTSSSDNVATSIQKVNNVINSAVLEEQIQVDIPVASLNLTEDKSLVTSSIAMDDAQTQRTDESKSCLQQTLANLEINLCAAEEEKLKIKKELEYLLKKHSVQEMDFLKEKKEKALSHEDHYKILQEKHKQELEDMRKAGHEALSIIVEEFKSLLQCTVQQQEAATEKQYILAIEKHSYKCQELLDVQHQRLLDILEAEKEVLSEKIEEALMQQSQKHKEMLDKCLDEERKRSKEAVAAAAKAEKEIVQEVVLKAVEEERRNMEKIHEEERNMWKAEHERLNKKIAQAVWEAMQEQRRHNEEIIKEALMEERKQSEKAIEEAVKRTREELMEYIKEQKRLDQVIRQRNLSSLELFLSCAQKQLSSLLNEEPTTTQEKRD", "length": 444, "header": "tr|A0A8V0ZMP6-1|A0A8V0ZMP6_CHICK Isoform 1 of Coiled-coil domain containing 91 OS=Gallus gallus OX=9031 GN=CCDC91 PE=4 SV=1 CANONICAL=A0A8V0ZMP6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6/entry#A0A8V0ZHD8-1", "sequence": { "sequence": "MDDDDFGGFEAAESYECGNGDKQMTSPAIPWAAFPTEFEVHISQNVSPDVLLEHCVPSSFLDASDSFTSSSDNVATSIQKVNNVINSAVLEEQIQVDIPVASLNLTEDKSLVTSSIAMDDAQTQRTDESKSCLQQTLANLEINLCAAEEEKLKIKKELEYLLKKHSVQEMDFLKEKKEKALSHEDHYKILQEKHKQELEDMRKAGHEALSIIVEEFKSLLQCTVQQQEAATEKQYILAIEKHSYKCQELLDVQHQRLLDILEAEKEVLSEKIEEALMQQSQKHKEMLDKCLDEERKRSKEAVAAAAKAEKEIVQEVVLKAVEEERRNMEKIHEEERNMWKAEHERLNKKIAQAVWEAMQEQRRHNEEIIKEALMEERKQSEKAIEEAVKRTREELMEYIKEQKRGIQGVFQVCLTP", "length": 416, "header": "tr|A0A8V0ZHD8-1|A0A8V0ZMP6_CHICK Computationally mapped isoform of Coiled-coil domain containing 91 OS=Gallus gallus OX=9031 GN=CCDC91 PE=4 SV=1 CANONICAL=A0A8V0ZMP6-1" }, "locus": { "chromosome": "1", "start_pos": 73158056, "end_pos": 72995077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054227.1", "url": "https://www.ensembl.org/id/ENSGALT00010054227.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032735.1", "url": "https://www.ensembl.org/id/ENSGALP00010032735.1" } ] } }, { "isoform_ac": "A0A8V0ZMP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6/entry#A0A8V0ZMP1-1", "sequence": { "sequence": "MDDDDFGGFEAAESYECGNGDKQMTSPAIPWAAFPTEFEVHISQNVSPDVLLEHCVPSSFLDASDSFTSSSDNVATSIQKVNNVINSAVLEEQIQVDIPVASLNLTEDKSLVTSSIAMDDAQTQRTDESKSCLQQTLANLEINLCAAEEEKLKIKKELEYLLKKHSVQEMDFLKEKKEKALSHEDHYKILQEKHKQELEDMRKAGHEALSIIVEEFKSLLQCTVQQQEAATEKQYILAIEKHSYKCQELLDVQHQRLLDILEAEKEVLSEKIEEALMQQSQKHKEMLDKCLDEERKRSKEAVAAAAKAEKEIVQEVVLKAVEEERRNMEKIHEEERNMWKAEHERLNKKIAQAVWEAMQEQRRHNELDQVIRQRNLSSLELFLSCAQKQLSSLLNEEPTTTQEKRD", "length": 406, "header": "tr|A0A8V0ZMP1-1|A0A8V0ZMP1_CHICK Computationally mapped isoform of Coiled-coil domain containing 91 OS=Gallus gallus OX=9031 GN=CCDC91 PE=4 SV=1 CANONICAL=A0A8V0ZMP6-1" }, "locus": { "chromosome": "1", "start_pos": 73115597, "end_pos": 72995077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054215.1", "url": "https://www.ensembl.org/id/ENSGALT00010054215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032727.1", "url": "https://www.ensembl.org/id/ENSGALP00010032727.1" } ] } }, { "isoform_ac": "A0A8V0ZMP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6/entry#A0A8V0ZMP6-1", "sequence": { "sequence": "MDDDDFGGFEAAESYECGNGDKQMTSPAIPWAAFPTEFEVHISQNVSPDVLLEHCVPSSFLDASDSFTSSSDNVATSIQKVNNVINSAVLEEQIQVDIPVASLNLTEDKSLVTSSIAMDDAQTQRTDESKSCLQQTLANLEINLCAAEEEKLKIKKELEYLLKKHSVQEMDFLKEKKEKALSHEDHYKILQEKHKQELEDMRKAGHEALSIIVEEFKSLLQCTVQQQEAATEKQYILAIEKHSYKCQELLDVQHQRLLDILEAEKEVLSEKIEEALMQQSQKHKEMLDKCLDEERKRSKEAVAAAAKAEKEIVQEVVLKAVEEERRNMEKIHEEERNMWKAEHERLNKKIAQAVWEAMQEQRRHNEEIIKEALMEERKQSEKAIEEAVKRTREELMEYIKEQKRLDQVIRQRNLSSLELFLSCAQKQLSSLLNEEPTTTQEKRD", "length": 444, "header": "tr|A0A8V0ZMP6-1|A0A8V0ZMP6_CHICK Isoform 1 of Coiled-coil domain containing 91 OS=Gallus gallus OX=9031 GN=CCDC91 PE=4 SV=1 CANONICAL=A0A8V0ZMP6-1" }, "locus": { "chromosome": "1", "start_pos": 73115597, "end_pos": 72995077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054222.1", "url": "https://www.ensembl.org/id/ENSGALT00010054222.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032732.1", "url": "https://www.ensembl.org/id/ENSGALP00010032732.1" } ] } }, { "isoform_ac": "A0A8V0ZPM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6/entry#A0A8V0ZPM7-1", "sequence": { "sequence": "MDDDDFGGFEAAESYECGNGDKQMTSPAIPWAAFPTEFEVHISQNVSPDVLLEHCVPSSFLDASDSFTSSSDNVATSIQKVNNVINSAVLEEQIQVDIPVASLNLTEDKSLVTSSIAMDDAQTQRTDESKSCLQQTLANLEINLCAAEEEKLKIKKELEYLLKKHSVQEMDFLKEKKEKALSHEDHYKILQEKHKQELEDMRKAGHEALSIIVEEFKSLLQCTVQQQEAATEKQYILAIEKHSYKCQELLDVQHQRLLDILEAEKEVLSEKIEEALMQQSQKHKEMLDKCLDEERKRSKEAVAAAAKAEKEIVQEVVLKAVEEERRNMEKIHEEERNMWKAEHERLNKKIAQAVWEAMQEQRRHNEEIIKEALMEERKQSEKAIEEAVKRTREELMEYIKEQKRNVKTDNCTMAIRRNKLPWHSPGGALNC", "length": 431, "header": "tr|A0A8V0ZPM7-1|A0A8V0ZPM7_CHICK Computationally mapped isoform of Coiled-coil domain containing 91 OS=Gallus gallus OX=9031 GN=CCDC91 PE=4 SV=1 CANONICAL=A0A8V0ZMP6-1" }, "locus": { "chromosome": "1", "start_pos": 73177492, "end_pos": 72995077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054286.1", "url": "https://www.ensembl.org/id/ENSGALT00010054286.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032784.1", "url": "https://www.ensembl.org/id/ENSGALP00010032784.1" } ] } }, { "isoform_ac": "A0A8V0ZPZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6/entry#A0A8V0ZPZ0-1", "sequence": { "sequence": "MSEFEVHISQNVSPDVLLEHCVPSSFLDASDSFTSSSDNVATSIQKVNNVINSAVLEEQIQVDIPVASLNLTEDKSLVTSSIAMDDAQTQRTDESKSCLQQTLANLEINLCAAEEEKLKIKKELEYLLKKHSVQEMDFLKEKKEKALSHEDHYKILQEKHKQELEDMRKAGHEALSIIVEEFKSLLQCTVQQQEAATEKQYILAIEKHSYKCQELLDVQHQRLLDILEAEKEVLSEKIEEALMQQSQKHKEMLDKCLDEERKRSKEAVAAAAKAEKEIVQEVVLKAVEEERRNMEKIHEEERNMWKAEHERLNKKIAQAVWEAMQEQRRHNEEIIKEALMEERKQSEKAIEEAVKRTREELMEYIKEQKRLDQVIRQRNLSSLELFLSCAQKQLSSLLNEEPTTTQEKRD", "length": 410, "header": "tr|A0A8V0ZPZ0-1|A0A8V0ZPZ0_CHICK Computationally mapped isoform of Coiled-coil domain containing 91 OS=Gallus gallus OX=9031 GN=CCDC91 PE=4 SV=1 CANONICAL=A0A8V0ZMP6-1" }, "locus": { "chromosome": "1", "start_pos": 73115597, "end_pos": 72996515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054209.1", "url": "https://www.ensembl.org/id/ENSGALT00010054209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032723.1", "url": "https://www.ensembl.org/id/ENSGALP00010032723.1" } ] } }, { "isoform_ac": "A0A8V0ZV44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6/entry#A0A8V0ZV44-1", "sequence": { "sequence": "MDDDDFGGFEAAESYECGNGDKQMTSPAIPWAAFPTEFEVHISQNVSPDVLLEHCVPSSFLDASDSFTSSSDNVATSIQKVNNVINSAVLEEQIQVDIPVASLNLTEDKSLVTSSIAMDDAQTQRTDESKSCLQQTLANLEINLCAAEEEKLKIKKELEYLLKKHSVQEMDFLKEKKEKALSHEDHYKILQEKHKQELEDMRKAGHEALSIIVEEFKSLLQCTVQQQEAATEKQYILAIEKHSYKCQELLDVQHQRLLDILEAEKEVLSEKIEEALMQQSQKHKEMLDKCLDEERKRSKEAVAAAAKAEKEIVQEVVLKAVEEERRNMEKIHEEERNMWKAEHERLNKKIAQAVWEAMQEQRRHNEEIIKEALMEERKQSEKAIEEAVKRTREELMEYIKEQKREYFCKIGSGNLGTRG", "length": 419, "header": "tr|A0A8V0ZV44-1|A0A8V0ZMP6_CHICK Computationally mapped isoform of Coiled-coil domain containing 91 OS=Gallus gallus OX=9031 GN=CCDC91 PE=4 SV=1 CANONICAL=A0A8V0ZMP6-1" }, "locus": { "chromosome": "1", "start_pos": 73083170, "end_pos": 72995077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054204.1", "url": "https://www.ensembl.org/id/ENSGALT00010054204.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032721.1", "url": "https://www.ensembl.org/id/ENSGALP00010032721.1" } ] } }, { "isoform_ac": "A0A8V0ZV78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6/entry#A0A8V0ZV78-1", "sequence": { "sequence": "MDDDDFGGFEAAESYECGNGDKQMTSPAIPWAAFPTEFEVHISQNVSPDVLLEHCVPSSFLDASDSFTSSSDNVATSIQKVNNVINSAVLEEQIQVDIPVASLNLTEDKSLVTSSIAMDDAQTQRTDESKSCLQQTLANLEINLCAAEEEKLKIKKELEYLLKKHSVQEMDFLKEKKEKALSHEDHYKILQEKHKQELEDMRKAGHEALSIIVEEFKSLLQCTVQQQEAATEKQYILAIEKHSYKCQELLDVQHQRLLDILEAEKEVLSEKIEEALMQQSQKHKEMLDKCLDEERKRSKEAVAAAAKAEKEIVQEVVLKAVEEERRNMEKIHEEERNMWKAEHERLNKKIAQAVWEAMQEQRRHNEEIIKEALMEERKQSEKAIEEAVKRTREELMEYIKEQKRNHRILKVGKDL", "length": 415, "header": "tr|A0A8V0ZV78-1|A0A8V0ZMP6_CHICK Computationally mapped isoform of Coiled-coil domain containing 91 OS=Gallus gallus OX=9031 GN=CCDC91 PE=4 SV=1 CANONICAL=A0A8V0ZMP6-1" }, "locus": { "chromosome": "1", "start_pos": 73149633, "end_pos": 72995077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054257.1", "url": "https://www.ensembl.org/id/ENSGALT00010054257.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032756.1", "url": "https://www.ensembl.org/id/ENSGALP00010032756.1" } ] } }, { "isoform_ac": "A0A8V0ZV92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6/entry#A0A8V0ZV92-1", "sequence": { "sequence": "MDDDDFGGFEAAESYECGNGDKQMTSPAIPWAAFPTEFEVHISQNVSPDVLLEHCVPSSFLDASDSFTSSSDNVATSIQKVNNVINSAVLEEQIQVDIPVASLNLTEDKSLVTSSIAMDDAQTQRTDESKSCLQQTLANLEINLCAAEEEKLKIKKELEYLLKKHSVQEMDFLKEKKEKALSHEDHYKILQEKHKQELEDMRKAGHEALSIIVEEFKSLLQCTVQQQEAATEKQYILAIEKHSYKCQELLDVQHQRLLDILEAEKEVLSEKIEEALMQQSQKHKEMLDKCLDEERKRSKEAVAAAAKAEKEIVQEVVLKAVEEERRNMEKIHEEERNMWKAEHERLNKKIAQAVWEAMQEQRRHNEEIIKEALMEERKQSEKAIEEAVKRTREELMEYIKEQKRFLTVTALPVRSWEKVEPQALIQTGQRDILYHMVPH", "length": 439, "header": "tr|A0A8V0ZV92-1|A0A8V0ZMP6_CHICK Computationally mapped isoform of Coiled-coil domain containing 91 OS=Gallus gallus OX=9031 GN=CCDC91 PE=4 SV=1 CANONICAL=A0A8V0ZMP6-1" }, "locus": { "chromosome": "1", "start_pos": 73164736, "end_pos": 72995077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054270.1", "url": "https://www.ensembl.org/id/ENSGALT00010054270.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032771.1", "url": "https://www.ensembl.org/id/ENSGALP00010032771.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6" } ], "pmid": "" }, { "name": "Golgi to lysosome transport", "id": "GO:0090160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMS9-1", "uniprot_ac": "A0A8V0ZMS9", "uniprot_id": "A0A8V0ZMS9_CHICK", "mass": { "chemical_mass": 47369.0, "monoisotopic_mass": 47369.0 }, "refseq": {}, "gene_names": [ { "name": "ADAP1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" } ] } ], "protein_names": [ { "name": "ArfGAP with dual PH domains 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9", "locus": { "chromosome": "14", "start_pos": 2192009, "end_pos": 2241572, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022304", "url": "https://www.ensembl.org/id/ENSGALG00010022304" } ] } } ], "crossref": [ { "id": "A0A8V0ZMS9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMS9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01251", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01251", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08843", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08843", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13252", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13252", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416451", "url": "https://www.ncbi.nlm.nih.gov/gene/416451", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416451", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416451", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YYNRNDA", "url": "https://omabrowser.org/oma/group/YYNRNDA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHG4", "url": "https://www.orthodb.org/?gene=A0A8V0ZHG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHI5", "url": "https://www.orthodb.org/?gene=A0A8V0ZHI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMS9", "url": "https://www.orthodb.org/?gene=A0A8V0ZMS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ27", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ36", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ43", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46021", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46021", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46021:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46021:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERVENEQKMGNLTVLCSHMVVLLTWYSWDRQQVRSPDGCGRFSAEHVPFPEILSWSHDPDWASHSLGIFICLNCSGIHRNIPQVSKVKSVRLDDWDDAQVEFMASNGNNVAKAKYESKMPPFYYKPTFLDCQLLREQWIRAKYERKEFIHSEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLSEREGALKYFNRNDAKEPKAIMKIEHLNATFQPAKIGNPHGLQITYLKDNSTRNIFVYHEDGKEIVDWFNAIRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFKKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKENSYKVLEGLPPSTQGNHWQHGITIVTPDRKFLFACETEDDQLEWITTFQKVISRPMLPQEYAVEAHFKHKP", "length": 405, "header": "tr|A0A8V0ZMS9-1|A0A8V0ZMS9_CHICK Isoform 1 of ArfGAP with dual PH domains 1 OS=Gallus gallus OX=9031 GN=ADAP1 PE=4 SV=1 CANONICAL=A0A8V0ZMS9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9/entry#A0A8V0ZHG4-1", "sequence": { "sequence": "MLIMNPDWASHSLGIFICLNCSGIHRNIPQVSKVKSVRLDDWDDAQVEFMASNGNNVAKAKYESKMPPFYYKPTFLDCQLLREQWIRAKYERKEFIHSEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLSEREGALKYFNRNDAKEPKAIMKIEHLNATFQPAKIGNPHGLQITYLKDNSTRNIFVYHEDGKEIVDWFNAIRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFKKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKENSYKVLEGLPPSTQGNHWQHGITIVTPDRKFLFACETEDDQLEWITTFQKVISRPMLPQEYAVEAHFKHKP", "length": 351, "header": "tr|A0A8V0ZHG4-1|A0A8V0ZMS9_CHICK Computationally mapped isoform of ArfGAP with dual PH domains 1 OS=Gallus gallus OX=9031 GN=ADAP1 PE=4 SV=1 CANONICAL=A0A8V0ZMS9-1" }, "locus": { "chromosome": "14", "start_pos": 2225837, "end_pos": 2194917, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054263.1", "url": "https://www.ensembl.org/id/ENSGALT00010054263.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032760.1", "url": "https://www.ensembl.org/id/ENSGALP00010032760.1" } ] } }, { "isoform_ac": "A0A8V0ZHI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9/entry#A0A8V0ZHI5-1", "sequence": { "sequence": "MAKERSRKALAELLQRPGNAACADCAAPDPDWASHSLGIFICLNCSGIHRNIPQVSKVKSVRLDDWDDAQVEFMASNGNNVAKAKYESKMPPFYYKPTFLDCQLLREQWIRAKYERKEFIHSEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLSEREGALKYFNRNDAKEPKAIMKIEHLNATFQPAKIGNPHGLQITYLKDNSTRNIFVYHEDGKEIVDWFNAIRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFKKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKENSYKVLEGLPPSTQGNHWQHGITIVTPDRKFLFACETEDDQLEWITTFQKVISRPMLPQEYAVEAHFKHKP", "length": 375, "header": "tr|A0A8V0ZHI5-1|A0A8V0ZMS9_CHICK Computationally mapped isoform of ArfGAP with dual PH domains 1 OS=Gallus gallus OX=9031 GN=ADAP1 PE=4 SV=1 CANONICAL=A0A8V0ZMS9-1" }, "locus": { "chromosome": "14", "start_pos": 2232300, "end_pos": 2194917, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054283.1", "url": "https://www.ensembl.org/id/ENSGALT00010054283.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032780.1", "url": "https://www.ensembl.org/id/ENSGALP00010032780.1" } ] } }, { "isoform_ac": "A0A8V0ZMS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9/entry#A0A8V0ZMS9-1", "sequence": { "sequence": "MERVENEQKMGNLTVLCSHMVVLLTWYSWDRQQVRSPDGCGRFSAEHVPFPEILSWSHDPDWASHSLGIFICLNCSGIHRNIPQVSKVKSVRLDDWDDAQVEFMASNGNNVAKAKYESKMPPFYYKPTFLDCQLLREQWIRAKYERKEFIHSEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLSEREGALKYFNRNDAKEPKAIMKIEHLNATFQPAKIGNPHGLQITYLKDNSTRNIFVYHEDGKEIVDWFNAIRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFKKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKENSYKVLEGLPPSTQGNHWQHGITIVTPDRKFLFACETEDDQLEWITTFQKVISRPMLPQEYAVEAHFKHKP", "length": 405, "header": "tr|A0A8V0ZMS9-1|A0A8V0ZMS9_CHICK Isoform 1 of ArfGAP with dual PH domains 1 OS=Gallus gallus OX=9031 GN=ADAP1 PE=4 SV=1 CANONICAL=A0A8V0ZMS9-1" }, "locus": { "chromosome": "14", "start_pos": 2230544, "end_pos": 2194917, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054271.1", "url": "https://www.ensembl.org/id/ENSGALT00010054271.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032767.1", "url": "https://www.ensembl.org/id/ENSGALP00010032767.1" } ] } }, { "isoform_ac": "A0A8V0ZQ27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9/entry#A0A8V0ZQ27-1", "sequence": { "sequence": "MGSSCSAQCWVGSADPDWASHSLGIFICLNCSGIHRNIPQVSKVKSVRLDDWDDAQVEFMASNGNNVAKAKYESKMPPFYYKPTFLDCQLLREQWIRAKYERKEFIHSEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLSEREGALKYFNRNDAKEPKAIMKIEHLNATFQPAKIGNPHGLQITYLKDNSTRNIFVYHEDGKEIVDWFNAIRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFKKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKENSYKVLEGLPPSTQGNHWQHGITIVTPDRKFLFACETEDDQLEWITTFQKVISRPMLPQEYAVEAHFKHKP", "length": 361, "header": "tr|A0A8V0ZQ27-1|A0A8V0ZQ27_CHICK Computationally mapped isoform of ArfGAP with dual PH domains 1 OS=Gallus gallus OX=9031 GN=ADAP1 PE=4 SV=1 CANONICAL=A0A8V0ZMS9-1" }, "locus": { "chromosome": "14", "start_pos": 2226009, "end_pos": 2194917, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054267.1", "url": "https://www.ensembl.org/id/ENSGALT00010054267.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032763.1", "url": "https://www.ensembl.org/id/ENSGALP00010032763.1" } ] } }, { "isoform_ac": "A0A8V0ZQ36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9/entry#A0A8V0ZQ36-1", "sequence": { "sequence": "MGEGGDELSRTAVKESRYPDWASHSLGIFICLNCSGIHRNIPQVSKVKSVRLDDWDDAQVEFMASNGNNVAKAKYESKMPPFYYKPTFLDCQLLREQWIRAKYERKEFIHSEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLSEREGALKYFNRNDAKEPKAIMKIEHLNATFQPAKIGNPHGLQITYLKDNSTRNIFVYHEDGKEIVDWFNAIRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFKKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKENSYKVLEGLPPSTQGNHWQHGITIVTPDRKFLFACETEDDQLEWITTFQKVISRPMLPQEYAVEAHFKHKP", "length": 364, "header": "tr|A0A8V0ZQ36-1|A0A8V0ZQ36_CHICK Computationally mapped isoform of ArfGAP with dual PH domains 1 OS=Gallus gallus OX=9031 GN=ADAP1 PE=4 SV=1 CANONICAL=A0A8V0ZMS9-1" }, "locus": { "chromosome": "14", "start_pos": 2232769, "end_pos": 2194917, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054276.1", "url": "https://www.ensembl.org/id/ENSGALT00010054276.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032773.1", "url": "https://www.ensembl.org/id/ENSGALP00010032773.1" } ] } }, { "isoform_ac": "A0A8V0ZQ43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9/entry#A0A8V0ZQ43-1", "sequence": { "sequence": "MGTSHRAFQRDPDWASHSLGIFICLNCSGIHRNIPQVSKVKSVRLDDWDDAQVEFMASNGNNVAKAKYESKMPPFYYKPTFLDCQLLREQWIRAKYERKEFIHSEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLSEREGALKYFNRNDAKEPKAIMKIEHLNATFQPAKIGNPHGLQITYLKDNSTRNIFVYHEDGKEIVDWFNAIRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFKKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKENSYKVLEGLPPSTQGNHWQHGITIVTPDRKFLFACETEDDQLEWITTFQKVISRPMLPQEYAVEAHFKHKP", "length": 357, "header": "tr|A0A8V0ZQ43-1|A0A8V0ZQ43_CHICK Computationally mapped isoform of ArfGAP with dual PH domains 1 OS=Gallus gallus OX=9031 GN=ADAP1 PE=4 SV=1 CANONICAL=A0A8V0ZMS9-1" }, "locus": { "chromosome": "14", "start_pos": 2241521, "end_pos": 2194917, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054287.1", "url": "https://www.ensembl.org/id/ENSGALT00010054287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032783.1", "url": "https://www.ensembl.org/id/ENSGALP00010032783.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416451", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416451", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZRW6-1", "protein_name": "ArfGAP with dual PH domains 1", "gene_name": "Adap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPQGPWCPWEETLTKLQWEAGQDEVVLSWSPEALQGPAMVQWGGGSLVLHGSHLPLSDLPFNMFGKAGYARVSGVPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWDETQVEFMTSHGNEAARATFESKVPPFYYRPTFSDCQLLREQWIRAKYERQEFLHVEKQEPYSTGYREGLLWKRGRDNGQFLSRKFVLTEREGALKYFNKNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLEGLPPSTQSHHWPHGITIVTPDRKFLFTCETESDQREWIAAFQKVVDRPMLPQEYAVEAHFKHKP", "length": 424 }, "evidence": [ { "id": "A0A8V0ZMS9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMS9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PY16-1", "protein_name": "ArfGAP with dual PH domains 1", "gene_name": "Adap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGERRRALLELLTRPGNTRCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWDEAQVEFMASHGNEAARATFESKVPPFYYRPTFSDCQLLREQWIRAKYERQEFVHVEKQEPYSTGYREGLLWKRGRDNGQFLSRKFVLTEREGALKYFNKNDAKEPKAVMKIEHLNATFQPAKMGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLEGLPLSTQGHHWPHGITIVTPDRKFLFTCETESDQREWIAAFQKVVDRPMLPQEYAVEAHFKHKP", "length": 374 }, "evidence": [ { "id": "A0A8V0ZMS9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMS9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1RIX6-1", "protein_name": "ArfGAP with dual PH domains 1", "gene_name": "ADAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKERRRAVLELLQRPGNAHCADCGAPDPDWSYTLGVFICLSCSGIHRNIPQVSKVKSVRLDTWEEPQVEFMASRGNSAARAVFESRVPPFYYRPSASDCQLLREQWIRAKYERQEFTHPERQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRSDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFVYHEDGKEMVDWFNALRAARFHYLQVAFPGASDADLVPKLSRNYLQEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSRESGYTVLDGLPPSTQGHHWPHGITIVTPERRFLLACETEPEQRAWMEAFRKVVDRPMLPQEYAVEAHFKHKP", "length": 373 }, "evidence": [ { "id": "A0A8V0ZMS9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMS9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75689-1", "protein_name": "Arf-GAP with dual PH domain-containing protein 1", "gene_name": "ADAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSDCQLLREQWIRAKYERQEFIYPEKQEPYSAGYREGFLWKRGRDNGQFLSRKFVLTEREGALKYFNRNDAKEPKAVMKIEHLNATFQPAKIGHPHGLQVTYLKDNSTRNIFIYHEDGKEIVDWFNALRAARFHYLQVAFPGAGDADLVPKLSRNYLKEGYMEKTGPKQTEGFRKRWFTMDDRRLMYFKDPLDAFARGEVFIGSKESGYTVLHGFPPSTQGHHWPHGITIVTPDRKFLFACETESDQREWVAAFQKAVDRPMLPQEYAVEAHFKHKP", "length": 374 }, "evidence": [ { "id": "A0A8V0ZMS9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMS9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "phosphatidylinositol bisphosphate binding", "id": "GO:1902936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" } ], "pmid": "" }, { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" } ], "pmid": "" }, { "name": "anion binding", "id": "GO:0043168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 157, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZMS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS9" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 261, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJ31-1", "uniprot_ac": "A0A8V0ZJ31", "uniprot_id": "A0A8V0ZJ31_CHICK", "mass": { "chemical_mass": 70252.0, "monoisotopic_mass": 70252.0 }, "refseq": { "ac": "XP_015145528", "name": "mitogen-activated protein kinase kinase kinase 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145528" }, "gene_names": [ { "name": "MAP3K2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ] }, { "name": "MAP3K2", "type": "synonym", "evidence": [ { "id": "XP_015145528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145528" } ] } ], "protein_names": [ { "name": "Mitogen-activated protein kinase kinase kinase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31/entry#names_and_taxonomy" } ] }, { "name": "mitogen-activated protein kinase kinase kinase 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015145528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145528" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145528" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAP3K2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31", "locus": { "chromosome": "7", "start_pos": 23245087, "end_pos": 23208148, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021275", "url": "https://www.ensembl.org/id/ENSGALG00010021275" } ] } } ], "crossref": [ { "id": "A0A8V0ZJ31", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJ31", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06405", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06405", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06652", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06652", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424225", "url": "https://www.ncbi.nlm.nih.gov/gene/424225", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424225", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424225", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPTNRDR", "url": "https://omabrowser.org/oma/group/GPTNRDR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHJ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZHJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ26", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ31", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPW4", "url": "https://www.orthodb.org/?gene=A0A8V0ZPW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11584", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11584", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11584:SF369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11584:SF369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00564", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00564", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145528", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPW4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEQQALNSIMQDLAVLHKASRPALPQQETGKPKSSSPKKQNDVRVKFEHRGEKRILQLPRPVKLEDLVAKAKVAFGQTMDLHYCNNELVIPLTTQDDLDKAVELLDRSVHMKSLKILLVIHGNTQSPSVNNVEPLPSLEDLDNTVFGVTERKRRLSVIGSNNRDRSSPPPGYIPDELHQVARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGDNYPKSRMPRAQSYPDNHQEFSVEYDIPIFEKFGKGGTYPRRYHISYHQQDYNDGRKTFPRARRTQGNSFRSPVSFSPTDHSLSTSSGSSVFTPEYEDNRMRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGFLRDPPERTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVLYLHTNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLPPHVSDHARDFLKRIFIEAKLRPFADELLRHTFAHYH", "length": 624, "header": "tr|A0A8V0ZJ31-1|A0A8V0ZJ31_CHICK Isoform 1 of Mitogen-activated protein kinase kinase kinase 2 OS=Gallus gallus OX=9031 GN=MAP3K2 PE=4 SV=1 CANONICAL=A0A8V0ZJ31-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31/entry#A0A8V0ZHJ3-1", "sequence": { "sequence": "MILQLPRPVKLEDLVAKAKVAFGQTMDLHYCNNELVIPLTTQDDLDKAVELLDRSVHMKSLKILLVIHGNTQSPSVNNVEPLPSLEDLDNTVFGVTERKRRLSVIGSNNRDRSSPPPGYIPDELHQVARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGDNYPKSRMPRAQSYPDNHQEFSVEYDIPIFEKFGKGGTYPRRYHISYHQQDYNDGRKTFPRARRTQGNSFRSPVSFSPTDHSLSTSSGSSVFTPEYEDNRMRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGFLRDPPERTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVLYLHTNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLPPHVSDHARDFLKRIFIEAKLRPFADELLRHTFAHYH", "length": 570, "header": "tr|A0A8V0ZHJ3-1|A0A8V0ZJ31_CHICK Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 2 OS=Gallus gallus OX=9031 GN=MAP3K2 PE=4 SV=1 CANONICAL=A0A8V0ZJ31-1" }, "locus": { "chromosome": "7", "start_pos": 23244528, "end_pos": 23230982, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051583.1", "url": "https://www.ensembl.org/id/ENSGALT00010051583.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030769.1", "url": "https://www.ensembl.org/id/ENSGALP00010030769.1" } ] } }, { "isoform_ac": "A0A8V0ZJ26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31/entry#A0A8V0ZJ26-1", "sequence": { "sequence": "MQWLSHQFLKQEVGKGSDSRVPLSGECGTLYQGAHAVMGRVPDLLNRWILQLPRPVKLEDLVAKAKVAFGQTMDLHYCNNELVIPLTTQDDLDKAVELLDRSVHMKSLKILLVIHGNTQSPSVNNVEPLPSLEDLDNTVFGVTERKRRLSVIGSNNRDRSSPPPGYIPDELHQVARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGDNYPKSRMPRAQSYPDNHQEFSVEYDIPIFEKFGKGGTYPRRYHISYHQQDYNDGRKTFPRARRTQGNSFRSPVSFSPTDHSLSTSSGSSVFTPEYEDNRMRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGFLRDPPERTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVLYLHTNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLPPHVSDHARDFLKRIFIEAKLRPFADELLRHTFAHYH", "length": 617, "header": "tr|A0A8V0ZJ26-1|A0A8V0ZJ26_CHICK Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 2 OS=Gallus gallus OX=9031 GN=MAP3K2 PE=4 SV=1 CANONICAL=A0A8V0ZJ31-1" }, "locus": { "chromosome": "7", "start_pos": 23244528, "end_pos": 23230631, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051585.1", "url": "https://www.ensembl.org/id/ENSGALT00010051585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030770.1", "url": "https://www.ensembl.org/id/ENSGALP00010030770.1" } ] } }, { "isoform_ac": "A0A8V0ZJ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31/entry#A0A8V0ZJ31-1", "sequence": { "sequence": "MDEQQALNSIMQDLAVLHKASRPALPQQETGKPKSSSPKKQNDVRVKFEHRGEKRILQLPRPVKLEDLVAKAKVAFGQTMDLHYCNNELVIPLTTQDDLDKAVELLDRSVHMKSLKILLVIHGNTQSPSVNNVEPLPSLEDLDNTVFGVTERKRRLSVIGSNNRDRSSPPPGYIPDELHQVARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGDNYPKSRMPRAQSYPDNHQEFSVEYDIPIFEKFGKGGTYPRRYHISYHQQDYNDGRKTFPRARRTQGNSFRSPVSFSPTDHSLSTSSGSSVFTPEYEDNRMRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGFLRDPPERTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVLYLHTNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLPPHVSDHARDFLKRIFIEAKLRPFADELLRHTFAHYH", "length": 624, "header": "tr|A0A8V0ZJ31-1|A0A8V0ZJ31_CHICK Isoform 1 of Mitogen-activated protein kinase kinase kinase 2 OS=Gallus gallus OX=9031 GN=MAP3K2 PE=4 SV=1 CANONICAL=A0A8V0ZJ31-1" }, "locus": { "chromosome": "7", "start_pos": 23244528, "end_pos": 23224185, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051592.1", "url": "https://www.ensembl.org/id/ENSGALT00010051592.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030775.1", "url": "https://www.ensembl.org/id/ENSGALP00010030775.1" } ] } }, { "isoform_ac": "A0A8V0ZPW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31/entry#A0A8V0ZPW4-1", "sequence": { "sequence": "MQDLAVLHKASRPALPQQETGKPKSSSPKKQNDVRVKFEHRGEKRILQLPRPVKLEDLVAKAKVAFGQTMDLHYCNNELVIPLTTQDDLDKAVELLDRSVHMKSLKILLVIHGNTQSPSVNNVEPLPSLEDLDNTVFGVTERKRRLSVIGSNNRDRSSPPPGYIPDELHQVARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGDNYPKSRMPRAQSYPDNHQEFSVEYDIPIFEKFGKGGTYPRRYHISYHQQDYNDGRKTFPRARRTQGNSFRSPVSFSPTDHSLSTSSGSSVFTPEYEDNRMRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGFLRDPPERTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVLYLHTNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLPPHVSDHARDFLKRIFIEAKLRPFADELLRHTFAHYH", "length": 614, "header": "tr|A0A8V0ZPW4-1|A0A8V0ZPW4_CHICK Computationally mapped isoform of Mitogen-activated protein kinase kinase kinase 2 OS=Gallus gallus OX=9031 GN=MAP3K2 PE=4 SV=1 CANONICAL=A0A8V0ZJ31-1" }, "locus": { "chromosome": "7", "start_pos": 23244528, "end_pos": 23226918, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051589.1", "url": "https://www.ensembl.org/id/ENSGALT00010051589.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030773.1", "url": "https://www.ensembl.org/id/ENSGALP00010030773.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424225", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424225", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F683-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 2", "gene_name": "map3k2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDEQEALNSIMQDLAVLHRSSRPSVLSDLAKPKASSPKNQNDVRVKFEYRGEKRILQFPRPVSLEDLSAKAKVAFGQSMDLHYTNNELVIPLSTQDDLDKAVELLDRSVHMKSLKILLVLPSWSQNCVSSKDLLPTHDILDNTDFSAPDKKSMLAHIGSQSTDRSSPPPGYIPDALQQVARNGSFTSINSEGEFIPESMDQMLDPLSMSSPENSASGSCPSLDSPLDSDTYPKSRMPRALSYPDNHQEFPEYDIPVFEKTGKGGTYPRRYHIPFGLQDYSDGRKTFPRARRTQAHGFRSPVSFSPTEQQSPSTSSGSSIFTPELEEPGRRRRGSDIEPSSNPTLSVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVFLCYDADTGRELAVKQVQFDPDSPETSKEVSALECEIQLLKNLFHERIVQYYGCLRDTHEKTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVCYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASRRLQTICLSGTGIKSVTGTPYWMSPEVISGEGYGRKADIWSIGCTVVEMLTQRPPWAEFEAMAAIFKIATQPTNPTLPPHVSDHCRDFLKRIFVETKQRPAAEDLLRHTFVH", "length": 623 }, "evidence": [ { "id": "A0A8V0ZJ31", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ31/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M9D0-1", "protein_name": "mitogen-activated protein kinase kinase kinase", "gene_name": "Map3k2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKPSSPKKQNDVRVKFEHRGEKRILQVTRPVKLEDLRSKSKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHMKSLKILLVLNGSTQATNLEPSPSPDDLNNTPLGAERKKRLSVVGPPNRDRSSPPPGYIPDELHQIARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFSDYDNPIFEKFGKGGTYPRRYHVSYHHQEYNDGRKTFPRARRTQGTSFRSPVSFSPTDHSLSTSSGSSIFTPEYEDSRIRRRGSDIDNPTLTVTDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPDSPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFVEAKLRPSAEELLRHLFVHCH", "length": 619 }, "evidence": [ { "id": "A0A8V0ZJ31", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ31/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MSX4-1", "protein_name": "mitogen-activated protein kinase kinase kinase", "gene_name": "MAP3K2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMDDQQALNSIMQDLAVLHKASRPALSLQETRKTKSSSPKKQNDVRVKFEHRGEKRILQFPRPVKLEDLRSKAKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHMKSLKILLVINGSAQATNLEPLPSLEDLDNTVFGAERKKGLSVVGPTSRDRSSPPPGYIPDELHQVARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFSDYDNPIFEKFGKGGTYPRRYHISYHHQDYNDGRKTFPRARRTQGTSFRSPVSFSPTDHSLSTSSGSSIFTPEYDESRIRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFVEAKLRPPADDLLRHTFVHCH", "length": 620 }, "evidence": [ { "id": "A0A8V0ZJ31", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ31/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q61083-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 2", "gene_name": "Map3k2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKPSSPKKQNDVRVKFEHRGEKRILQVTRPVKLEDLRSKSKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHMKSLKILLVVNGSTQATNLEPSPSPEDLNNTPLGAERKKRLSVVGPPNRDRSSPPPGYIPDILHQIARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFTDYDNPIFEKFGKGGTYPRRYHVSYHHQEYNDGRKTFPRARRTQGTSFRSPVSFSPTDHSLSTSSGSSVFTPEYDDSRIRRRGSDIDNPTLTVTDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFVEAKLRPSAEELLRHMFVHYH", "length": 619 }, "evidence": [ { "id": "A0A8V0ZJ31", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ31/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2U5-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 2", "gene_name": "MAP3K2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKSSSPKKQNDVRVKFEHRGEKRILQFPRPVKLEDLRSKAKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHMKSLKILLVINGSTQATNLEPLPSLEDLDNTVFGAERKKRLSIIGPTSRDRSSPPPGYIPDELHQVARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFSDYDNPIFEKFGKGGTYPRRYHVSYHHQEYNDGRKTFPRARRTQGTSLRSPVSFSPTDHSLSTSSGSSIFTPEYDDSRIRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFVEAKLRPSADELLRHMFVHYH", "length": 619 }, "evidence": [ { "id": "A0A8V0ZJ31", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ31/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "pmid": "" }, { "name": "JNK cascade", "id": "GO:0007254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "pmid": "" }, { "name": "cellular response to mechanical stimulus", "id": "GO:0071260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" }, { "id": "PS51745", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51745" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PB1", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 122, "start_aa": "Asp", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZJ31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ31" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 361, "end_pos": 621, "start_aa": "Trp", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 184, "end_pos": 186 }, { "start_pos": 463, "end_pos": 465 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJ74-1", "uniprot_ac": "A0A8V0ZJ74", "uniprot_id": "A0A8V0ZJ74_CHICK", "mass": { "chemical_mass": 58329.0, "monoisotopic_mass": 58329.0 }, "refseq": { "ac": "XP_025008199", "name": "protein disulfide-isomerase A5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008199" }, "gene_names": [ { "name": "PDIA5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74" } ] }, { "name": "PDIA5", "type": "synonym", "evidence": [ { "id": "XP_025008199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008199" } ] } ], "protein_names": [ { "name": "Protein disulfide-isomerase A5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74/entry#names_and_taxonomy" } ] }, { "name": "5.3.4.1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74/entry#names_and_taxonomy" } ] }, { "name": "protein disulfide-isomerase A5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_025008199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008199" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025008199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008199" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PDIA5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74", "locus": { "chromosome": "7", "start_pos": 26534190, "end_pos": 26442940, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021338", "url": "https://www.ensembl.org/id/ENSGALG00010021338" } ] } } ], "crossref": [ { "id": "A0A8V0ZJ74", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJ74", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02997", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02997", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03067", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03067", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424249", "url": "https://www.ncbi.nlm.nih.gov/gene/424249", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424249", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424249", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZHR1", "url": "https://www.orthodb.org/?gene=A0A8V0ZHR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHR7", "url": "https://www.orthodb.org/?gene=A0A8V0ZHR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ69", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ74", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45672", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45672", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45672:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45672:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025008199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008199", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQAFLLAFGYSLKLSPLIEKISDHKDFKKLLRTRNNVLVLYSKSAAAAESSLRLLSNVAQEVKGRGTISWIDCGDTESRKLCKKMKVDPNSKEKGVELLHYKDGAFHTEYNRAVTLKSMVAFLKDPEGAPLWEEDPEAKDIVHVDSEKELRRLLKKEDKPLLMMFYAPWCGVCKRMMPSFQQAATELKGKYVLAGMNVYSAEFERIKEEYNVRGYPTICYFEKGKFLFHFENYGATAADIAEWLKNPQAPQPQAPEIPWADEENVVYHLTDEDFDKFIKDHSSVLVMFHAPWCGHCKKMKPEYEKAAEFLHAGSDSPGVLAAVDATVNKALAERYHISGFPTVKYFKDGEEKYTLPHLRTKKKIIDWLQNPEAPPPPEPAWEEKQSSVVHLAGEDFRESLKKKKHTLVMFYAPWCPHCKNAIPHFTTAAEVFKEDRKIAYAAVDCAKDQNHDLCKQEGVDGYPTFNYYNYGKFVEKYTGERGEAGFTTFMRTLRERDHERVGKKKDEL", "length": 508, "header": "tr|A0A8V0ZJ74-1|A0A8V0ZJ74_CHICK Isoform 1 of Protein disulfide-isomerase A5 OS=Gallus gallus OX=9031 GN=PDIA5 PE=1 SV=1 CANONICAL=A0A8V0ZJ74-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74/entry#A0A8V0ZHR1-1", "sequence": { "sequence": "MLWDLLRKMLGCLMHRSRFRAFLLAFGYSLKLSPLIEKISDHKDFKKLLRTRNNVLVLYSKSAAAAESSLRLLSNVAQEVKGRGTISWIDCGDTESRKLCKKMKVDPNSKEKGVELLHYKDGAFHTEYNRAVTLKSMVAFLKDPEGAPLWEEDPEAKDIVHVDSEKELRRLLKKEDKPLLMMFYAPWCGVCKRMMPSFQQAATELKGKYVLAGMNVYSAEFERIKEEYNVRGYPTICYFEKGKFLFHFENYGATAADIAEWLKNPQAPQPQAPEIPWADEENVVYHLTDEDFDKFIKDHSSVLVMFHAPWCGHCKKMKPEYEKAAEFLHAGSDSPGVLAAVDATVNKALAERYHISGFPTVKYFKDGEEKYTLPHLRTKKKIIDWLQNPEAPPPPEPAWEEKQSSVVHLAGEDFRESLKKKKHTLVMFYAPWCPHCKNAIPHFTTAAEVFKEDRKIAYAAVDCAKDQNHDLCKQEGVDGYPTFNYYNYGKFVEKYTGERGEAGFTTFMRTLRERDHERVGKKKDEL", "length": 526, "header": "tr|A0A8V0ZHR1-1|A0A8V0ZJ74_CHICK Computationally mapped isoform of Protein disulfide-isomerase A5 OS=Gallus gallus OX=9031 GN=PDIA5 PE=1 SV=1 CANONICAL=A0A8V0ZJ74-1" }, "locus": { "chromosome": "7", "start_pos": 26531949, "end_pos": 26444880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051710.1", "url": "https://www.ensembl.org/id/ENSGALT00010051710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030844.1", "url": "https://www.ensembl.org/id/ENSGALP00010030844.1" } ] } }, { "isoform_ac": "A0A8V0ZHR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74/entry#A0A8V0ZHR7-1", "sequence": { "sequence": "MAVPGQRAGAARCRGRFPLLLLGLTAFLLAFGYSLKLSPLIEKISDHKDFKKLLRTRNNVLVLYSKSAAAAESSLRLLSNVAQEVKGRGTISWIDCGDTESRKLCKKMKVDPNSKEKGVELLHYKDGAFHTEYNRAVTLKSMVAFLKDPEGAPLWEEDPEAKDIVHVDSEKELRRLLKKEDKPLLMMFYAPWCGVCKRMMPSFQQAATELKGKYVLAGMNVYSAEFERIKEEYNVRGYPTICYFEKGKFLFHFENYGATAADIAEWLKNPQAPQPQAPEIPWADEENVVYHLTDEDFDKFIKDHSSVLVMFHAPWCGHCKKMKPEYEKAAEFLHAGSDSPGVLAAVDATVNKALAERYHISGFPTVKYFKDGEEKYTLPHLRTKKKIIDWLQNPEAPPPPEPAWEEKQSSVVHLAGEDFRESLKKKKHTLVMFYAPWCPHCKNAIPHFTTAAEVFKEDRKIAYAAVDCAKDQNHDLCKQEGVDGYPTFNYYNYGKFVEKYTGERGVRGWIHHVHANP", "length": 517, "header": "tr|A0A8V0ZHR7-1|A0A8V0ZJ74_CHICK Computationally mapped isoform of Protein disulfide-isomerase A5 OS=Gallus gallus OX=9031 GN=PDIA5 PE=1 SV=1 CANONICAL=A0A8V0ZJ74-1" }, "locus": { "chromosome": "7", "start_pos": 26531903, "end_pos": 26442996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051718.1", "url": "https://www.ensembl.org/id/ENSGALT00010051718.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030849.1", "url": "https://www.ensembl.org/id/ENSGALP00010030849.1" } ] } }, { "isoform_ac": "A0A8V0ZJ69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74/entry#A0A8V0ZJ69-1", "sequence": { "sequence": "MAVPGQRAGAARCRGRFPLLLLGLTAFLLAFGYSLKLSPLIEKISDHKDFKKLLRTRNNVLVLYSKSAAAAESSLRLLSNVAQEVKGRGTISWIDCGDTESRKLCKKMKVDPNSKEKGVELLHYKDGAFHTEYNRAVTLKSMVAFLKDPEGAPLWEEDPEAKDIVHVDSEKELRRLLKKEDKPLLMMFYAPWCGVCKRMMPSFQQAATELKGKYVLAGMNVYSAEFERIKEEYNVRGYPTICYFEKGKFLFHFENYGATAADIAEWLKNPQAPQPQAPEIPWADEENVVYHLTDEDFDKFIKDHSSVLVMFHAPWCGHCKKMKPEYEKAAEFLHAGSDSPGVLAAVDATVNKALAERYHISGFPTVKYFKDGEEKYTLPHLRTKKKIIDWLQNPEAPPPPEPAWEEKQSSVVHLAGEDFRESLKKKKHTLVMFYAPWCPHCKNAIPHFTTAAEVFKEDRKVHLMAKAHHFISLHQLSHFN", "length": 480, "header": "tr|A0A8V0ZJ69-1|A0A8V0ZJ69_CHICK Computationally mapped isoform of Protein disulfide-isomerase A5 OS=Gallus gallus OX=9031 GN=PDIA5 PE=1 SV=1 CANONICAL=A0A8V0ZJ74-1" }, "locus": { "chromosome": "7", "start_pos": 26522545, "end_pos": 26442996, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051706.1", "url": "https://www.ensembl.org/id/ENSGALT00010051706.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030841.1", "url": "https://www.ensembl.org/id/ENSGALP00010030841.1" } ] } }, { "isoform_ac": "A0A8V0ZJ74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74/entry#A0A8V0ZJ74-1", "sequence": { "sequence": "MQAFLLAFGYSLKLSPLIEKISDHKDFKKLLRTRNNVLVLYSKSAAAAESSLRLLSNVAQEVKGRGTISWIDCGDTESRKLCKKMKVDPNSKEKGVELLHYKDGAFHTEYNRAVTLKSMVAFLKDPEGAPLWEEDPEAKDIVHVDSEKELRRLLKKEDKPLLMMFYAPWCGVCKRMMPSFQQAATELKGKYVLAGMNVYSAEFERIKEEYNVRGYPTICYFEKGKFLFHFENYGATAADIAEWLKNPQAPQPQAPEIPWADEENVVYHLTDEDFDKFIKDHSSVLVMFHAPWCGHCKKMKPEYEKAAEFLHAGSDSPGVLAAVDATVNKALAERYHISGFPTVKYFKDGEEKYTLPHLRTKKKIIDWLQNPEAPPPPEPAWEEKQSSVVHLAGEDFRESLKKKKHTLVMFYAPWCPHCKNAIPHFTTAAEVFKEDRKIAYAAVDCAKDQNHDLCKQEGVDGYPTFNYYNYGKFVEKYTGERGEAGFTTFMRTLRERDHERVGKKKDEL", "length": 508, "header": "tr|A0A8V0ZJ74-1|A0A8V0ZJ74_CHICK Isoform 1 of Protein disulfide-isomerase A5 OS=Gallus gallus OX=9031 GN=PDIA5 PE=1 SV=1 CANONICAL=A0A8V0ZJ74-1" }, "locus": { "chromosome": "7", "start_pos": 26531949, "end_pos": 26444029, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051713.1", "url": "https://www.ensembl.org/id/ENSGALT00010051713.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030846.1", "url": "https://www.ensembl.org/id/ENSGALP00010030846.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424249", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424249", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74" } ], "pmid": "" }, { "name": "protein disulfide isomerase activity", "id": "GO:0003756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ74" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin", "eco_id": "ECO_0000259", "start_pos": 123, "end_pos": 249, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.3.4.1", "ec_name": "Catalyzes the rearrangement of -S-S- bonds in proteins.", "evidence": [ { "id": "5.3.4.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.3.4.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJS5-1", "uniprot_ac": "A0A8V0ZJS5", "uniprot_id": "A0A8V0ZJS5_CHICK", "mass": { "chemical_mass": 49327.0, "monoisotopic_mass": 49327.0 }, "refseq": {}, "gene_names": [ { "name": "MANSC1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS5" } ] } ], "protein_names": [ { "name": "MANSC domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MANSC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS5", "locus": { "chromosome": "1", "start_pos": 71874902, "end_pos": 71886634, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021419", "url": "https://www.ensembl.org/id/ENSGALG00010021419" } ] } } ], "crossref": [ { "id": "A0A8V0ZJS5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "426428", "url": "https://www.ncbi.nlm.nih.gov/gene/426428", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426428", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426428", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SQNCPTK", "url": "https://omabrowser.org/oma/group/SQNCPTK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI53", "url": "https://www.orthodb.org/?gene=A0A8V0ZI53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJS5", "url": "https://www.orthodb.org/?gene=A0A8V0ZJS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16021", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16021", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16021:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16021:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07502", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07502", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17823", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17823", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZI53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVRGLPLCLLAVSCAMPAPSRGQGCAAQRMDNAIIDINLSLPMGIRGAEPVHVPTPEACIHACCLGEKLSGGKKCNLVIFDAQRASTQPNCYLFHCPSTEACPMKPAMGLVSYKIAQDTHALEDTSFRNEDFSSNELSVPSDAGAFISQSQTSHQYHTTALQQSVFHQASELVNHMAKHVDNTEFHRVFPESQRADNPKSLDPLPRQKVINPPPNISYTVQTGNPSALFLTTESSVSSSSSTTVTPLPKSTVRLKPHTTSLLTGGTRPSTVTRTTTFMLTAIARAEPGIPTAKIAATRVFLSSLTTSASTSTAKWVTSNPVTATSSAGLRTSSIPPEPTAVSASYTSHVTLVSSSSFALSTSAPPMASLNNHKDYDPSDSEGTPSENVQGRKGFVQLEDKSRLVAALLFGVIFLLLVIALTGKKMHESLRKRQYTSLSSDRALTQVVESSPWRPSEAAWT", "length": 461, "header": "tr|A0A8V0ZJS5-1|A0A8V0ZJS5_CHICK Isoform 1 of MANSC domain containing 1 OS=Gallus gallus OX=9031 GN=MANSC1 PE=4 SV=1 CANONICAL=A0A8V0ZJS5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZI53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS5/entry#A0A8V0ZI53-1", "sequence": { "sequence": "MAVRGLPLCLLAVSCAMPAPSRGQGCAAQRMDNAIIDINLSLPMGIRGAEPVHVPTPEACIHACCLGEKLSGGKKCNLVIFDAQRASTQPNCYLFHCPSTEACPMKPAMGLVSYKIAQDTHALEDTSFRNEDFSSNELSVPSDAGAFISQSQTSHQYHTTALQQSVFHQASELVNHMAKHVDNTEFHRVFPESQRADNPKSLDPLPRQKVINPPPNISYTVQTGNPSALFLTTESSVSSSSSTTVTPLPKSTVRLKPHTTSLLTGGTRPSTVTRTTTFMLTAIARAEPGIPTAKIAATRVFLSSLTTSASTSTAKWVTSNPVTATSSAGLRTSSIPPEPTAVSASYTSHVTLVSSSSFALSTSAPPMASLNNHKDYDPSDSEGTPSENVQGRKGFVQLEDKSRLVAALLFGVIFLLLVIALTGKKMHESLRKRQYTRLDYLINGMYADV", "length": 449, "header": "tr|A0A8V0ZI53-1|A0A8V0ZJS5_CHICK Computationally mapped isoform of MANSC domain containing 1 OS=Gallus gallus OX=9031 GN=MANSC1 PE=4 SV=1 CANONICAL=A0A8V0ZJS5-1" }, "locus": { "chromosome": "1", "start_pos": 71886595, "end_pos": 71880679, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051933.1", "url": "https://www.ensembl.org/id/ENSGALT00010051933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030994.1", "url": "https://www.ensembl.org/id/ENSGALP00010030994.1" } ] } }, { "isoform_ac": "A0A8V0ZJS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS5/entry#A0A8V0ZJS5-1", "sequence": { "sequence": "MAVRGLPLCLLAVSCAMPAPSRGQGCAAQRMDNAIIDINLSLPMGIRGAEPVHVPTPEACIHACCLGEKLSGGKKCNLVIFDAQRASTQPNCYLFHCPSTEACPMKPAMGLVSYKIAQDTHALEDTSFRNEDFSSNELSVPSDAGAFISQSQTSHQYHTTALQQSVFHQASELVNHMAKHVDNTEFHRVFPESQRADNPKSLDPLPRQKVINPPPNISYTVQTGNPSALFLTTESSVSSSSSTTVTPLPKSTVRLKPHTTSLLTGGTRPSTVTRTTTFMLTAIARAEPGIPTAKIAATRVFLSSLTTSASTSTAKWVTSNPVTATSSAGLRTSSIPPEPTAVSASYTSHVTLVSSSSFALSTSAPPMASLNNHKDYDPSDSEGTPSENVQGRKGFVQLEDKSRLVAALLFGVIFLLLVIALTGKKMHESLRKRQYTSLSSDRALTQVVESSPWRPSEAAWT", "length": 461, "header": "tr|A0A8V0ZJS5-1|A0A8V0ZJS5_CHICK Isoform 1 of MANSC domain containing 1 OS=Gallus gallus OX=9031 GN=MANSC1 PE=4 SV=1 CANONICAL=A0A8V0ZJS5-1" }, "locus": { "chromosome": "1", "start_pos": 71886595, "end_pos": 71875906, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051997.1", "url": "https://www.ensembl.org/id/ENSGALT00010051997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031036.1", "url": "https://www.ensembl.org/id/ENSGALP00010031036.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426428", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426428", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AE21-1", "protein_name": "MANSC domain containing 1", "gene_name": "Mansc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLFGGHSLAYTLVIISFLTPRLSAGQNCFTKSLEDVVIDIQSSLSKGIRGNEPIHMAAQEDCIGACCSTHDIAGDKSCNLMIFDTRKTDRQPNCYLFFCPSEDACPLKPAKGLVSYRLFRDVPLTRANSSLQKLTQEESLLLGHALPGVTPGVPPPAGYPKPTGLFWRDLSSPKSTTSLHLQKYIQVDDASTQPPSYEGKNHSQSLQLPSELNMVHLLPKTPPFPTVAPRGSNVSATLKPALLLASISVTPKTSRPKDATTVPHVTTVTSESPAVPVSTGFIPVVSPQAALTTILQAHTDSKGIFKTVPFRGGSKLTSDTRHGKRPAATSLSTSESSVINKTAPWENGRISVGSIPRNRGPNTRHGLSFEKWLLIGTLLFGVLFLVIGLVLLGRMLVESLRRKRYSRLDYLINGIYVDI", "length": 419 }, "evidence": [ { "id": "A0A8V0ZJS5", "url": "https://omabrowser.org/oma/group/A0A8V0ZJS5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CR33-1", "protein_name": "MANSC domain-containing protein 1", "gene_name": "Mansc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFRGTSLAYSLLVISFLTPRSSAGQNCLTKSLEDVVIDIQSSLSKGIRGNEPIHLATQEDCIGACCSTKDIAGDKACNLMIFDTRKTDRQPNCYLFFCPSEDACPLKPAKGLVTYRLIRDFPLTSANSSLQQLTQGEFLLLDHSSPGATPGFRTPAGYPKPTGLSWSDRSSLKSTAPLHLRKHIKADETSMQLPEEKSHSQSLQLPSELKMAHLLPKTVPTPPTTVAVAPLRNVSATLKPELLLTSISVTAKTLKQKEATTASPVTTVTSKLPGVPGSTSFTPVVTHQAALTNTFQAHTDSKGILETMPFQGGSTLTSDPRHGKSSTSESSITNKTASWEDRRVSVGSASLNKGPKSQHGLSFEKWLLIGTLLCGVLFLVIGLVLLGRMLVEALRRKRYSRLDYLINGIYVDI", "length": 414 }, "evidence": [ { "id": "A0A8V0ZJS5", "url": "https://omabrowser.org/oma/group/A0A8V0ZJS5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8J5-1", "protein_name": "MANSC domain-containing protein 1", "gene_name": "MANSC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFFGGEGSLTYTLVIICFLTLRLSASQNCLKKSLEDVVIDIQSSLSKGIRGNEPVYTSTQEDCINSCCSTKNISGDKACNLMIFDTRKTARQPNCYLFFCPNEEACPLKPAKGLMSYRIITDFPSLTRNLPSQELPQEDSLLHGQFSQAVTPLAHHHTDYSKPTDISWRDTLSQKFGSSDHLEKLFKMDEASAQLLAYKEKGHSQSSQFSSDQEIAHLLPENVSALPATVAVASPHTTSATPKPATLLPTNASVTPSGTSQPQLATTAPPVTTVTSQPPTTLISTVFTRAAATLQAMATTAVLTTTFQAPTDSKGSLETIPFTEISNLTLNTGNVYNPTALSMSNVESSTMNKTASWEGREASPGSSSQGSVPENQYGLPFEKWLLIGSLLFGVLFLVIGLVLLGRILSESLRRKRYSRLDYLINGIYVDI", "length": 431 }, "evidence": [ { "id": "A0A8V0ZJS5", "url": "https://omabrowser.org/oma/group/A0A8V0ZJS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJS5" }, { "id": "PS50986", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50986" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MANSC", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 114, "start_aa": "Arg", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 }, { "start_pos": 39, "end_pos": 41 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKF9-1", "uniprot_ac": "A0A8V0ZKF9", "uniprot_id": "A0A8V0ZKF9_CHICK", "mass": { "chemical_mass": 22904.0, "monoisotopic_mass": 22904.0 }, "refseq": {}, "gene_names": [ { "name": "MYL9", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" } ] } ], "protein_names": [ { "name": "Myosin, light chain 9, regulatory", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9", "locus": { "chromosome": "20", "start_pos": 795086, "end_pos": 801859, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021572", "url": "https://www.ensembl.org/id/ENSGALG00010021572" } ] } } ], "crossref": [ { "id": "A0A8V0ZKF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIV3", "url": "https://www.orthodb.org/?gene=A0A8V0ZIV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKF9", "url": "https://www.orthodb.org/?gene=A0A8V0ZKF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23049", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23049", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13405", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13405", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-445355", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445355", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5627123", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5627123", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZIV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGICAATQGSCVRPFPSDSPALPAGTTPAANMSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD", "length": 204, "header": "tr|A0A8V0ZKF9-1|A0A8V0ZKF9_CHICK Isoform 1 of Myosin, light chain 9, regulatory OS=Gallus gallus OX=9031 GN=MYL9 PE=4 SV=1 CANONICAL=A0A8V0ZKF9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9/entry#A0A8V0ZIV3-1", "sequence": { "sequence": "MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMAAFTGKNPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD", "length": 176, "header": "tr|A0A8V0ZIV3-1|A0A8V0ZKF9_CHICK Computationally mapped isoform of Myosin, light chain 9, regulatory OS=Gallus gallus OX=9031 GN=MYL9 PE=4 SV=1 CANONICAL=A0A8V0ZKF9-1" }, "locus": { "chromosome": "20", "start_pos": 797546, "end_pos": 795552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052357.1", "url": "https://www.ensembl.org/id/ENSGALT00010052357.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031285.1", "url": "https://www.ensembl.org/id/ENSGALP00010031285.1" } ] } }, { "isoform_ac": "A0A8V0ZKF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9/entry#A0A8V0ZKF9-1", "sequence": { "sequence": "MSGICAATQGSCVRPFPSDSPALPAGTTPAANMSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD", "length": 204, "header": "tr|A0A8V0ZKF9-1|A0A8V0ZKF9_CHICK Isoform 1 of Myosin, light chain 9, regulatory OS=Gallus gallus OX=9031 GN=MYL9 PE=4 SV=1 CANONICAL=A0A8V0ZKF9-1" }, "locus": { "chromosome": "20", "start_pos": 797642, "end_pos": 795552, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052353.1", "url": "https://www.ensembl.org/id/ENSGALT00010052353.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031282.1", "url": "https://www.ensembl.org/id/ENSGALP00010031282.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 28, "start_aa": "Thr", "end_pos": 28, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr28", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-445355", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445355", "resource": "Reactome", "description": "Smooth Muscle Contraction" }, { "id": "R-GGA-5627123", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5627123", "resource": "Reactome", "description": "RHO GTPases activate PAKs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" } ], "pmid": "" }, { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" } ], "pmid": "" }, { "name": "myosin heavy chain binding", "id": "GO:0032036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" } ], "pmid": "" }, { "name": "myofibril", "id": "GO:0030016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030016", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" } ], "pmid": "" }, { "name": "myosin II complex", "id": "GO:0016460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016460", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "stress fiber assembly", "id": "GO:0043149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" } ], "pmid": "" }, { "name": "myofibril assembly", "id": "GO:0030239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030239", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF9" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 96, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 28 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 127, "end_pos": 129 }, { "start_pos": 32, "end_pos": 34 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJ00-1", "uniprot_ac": "A0A8V0ZJ00", "uniprot_id": "A0A8V0ZJ00_CHICK", "mass": { "chemical_mass": 61683.0, "monoisotopic_mass": 61683.0 }, "refseq": { "ac": "XP_015152579", "name": "leucine-rich repeat-containing protein 47", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152579" }, "gene_names": [ { "name": "LRRC47", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ00" } ] }, { "name": "LRRC47", "type": "synonym", "evidence": [ { "id": "XP_015152579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152579" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 47", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ00/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 47", "type": "synonym", "evidence": [ { "id": "XP_015152579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152579" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152579" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ00" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ00", "locus": { "chromosome": "21", "start_pos": 930459, "end_pos": 925485, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021267", "url": "https://www.ensembl.org/id/ENSGALG00010021267" } ] } } ], "crossref": [ { "id": "A0A8V0ZJ00", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJ00", "database": "AlphaFoldDB", "categories": [] }, { "id": "419380", "url": "https://www.ncbi.nlm.nih.gov/gene/419380", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419380", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419380", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YDVKPPT", "url": "https://omabrowser.org/oma/group/YDVKPPT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ00", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10947", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10947", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10947:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10947:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015152579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152579", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVWPEVAAAARERRRELTLQGAAVAERVAAGGGRLPAELLALPLLQSLQLSGCAALRELGPGLAAALPALHTLVLSGNALGPAGLGAGLGGPLPALRLLDLSGNGLEALPAALGGAGPPEEEGGEPAAFPQLRSLNLSGNRLRELGPGLARAAPQLQELLLSGNRLRALPGALLPPADAAPFPLLSRLEAADNEVEELSPDIAALPALKSLDVANNRLSALPAALADCPRLKDANLRGNPLRDRRLEKMVNGCQTRAVLEYLRSKGRADGGREETRRRKREKPQKKDGGDGERDEAEAVGKLLLKVLHVGDGPAPMVVRASPGVRDVRPYIVCCVLRGVQLRPGNALRRFLSAQTKLHEDICEKRTAATIATHDLQLVKGPLTYGVQPPAELKITPLGRKEIRAKDLLRQLQMEAEEQRKQKKRQNVSGLHRYLQLLDGKDNYPCLVDAEGVVISFPPITNSEKTKIRKTTRDLFLEVTSDTSLQICKDVMDALILKIAELNRFTLENKEEGSGSDDESDALCGPVNVNPNQNTQQPLVVEQVRVVDMDGNLKVLYPSKTDLATVSSLLTVIR", "length": 575, "header": "tr|A0A8V0ZJ00-1|A0A8V0ZJ00_CHICK Isoform 1 of Leucine rich repeat containing 47 OS=Gallus gallus OX=9031 GN=LRRC47 PE=1 SV=1 CANONICAL=A0A8V0ZJ00-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ00/entry#A0A8V0ZJ00-1", "sequence": { "sequence": "MAAVWPEVAAAARERRRELTLQGAAVAERVAAGGGRLPAELLALPLLQSLQLSGCAALRELGPGLAAALPALHTLVLSGNALGPAGLGAGLGGPLPALRLLDLSGNGLEALPAALGGAGPPEEEGGEPAAFPQLRSLNLSGNRLRELGPGLARAAPQLQELLLSGNRLRALPGALLPPADAAPFPLLSRLEAADNEVEELSPDIAALPALKSLDVANNRLSALPAALADCPRLKDANLRGNPLRDRRLEKMVNGCQTRAVLEYLRSKGRADGGREETRRRKREKPQKKDGGDGERDEAEAVGKLLLKVLHVGDGPAPMVVRASPGVRDVRPYIVCCVLRGVQLRPGNALRRFLSAQTKLHEDICEKRTAATIATHDLQLVKGPLTYGVQPPAELKITPLGRKEIRAKDLLRQLQMEAEEQRKQKKRQNVSGLHRYLQLLDGKDNYPCLVDAEGVVISFPPITNSEKTKIRKTTRDLFLEVTSDTSLQICKDVMDALILKIAELNRFTLENKEEGSGSDDESDALCGPVNVNPNQNTQQPLVVEQVRVVDMDGNLKVLYPSKTDLATVSSLLTVIR", "length": 575, "header": "tr|A0A8V0ZJ00-1|A0A8V0ZJ00_CHICK Isoform 1 of Leucine rich repeat containing 47 OS=Gallus gallus OX=9031 GN=LRRC47 PE=1 SV=1 CANONICAL=A0A8V0ZJ00-1" }, "locus": { "chromosome": "21", "start_pos": 929416, "end_pos": 925684, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051560.1", "url": "https://www.ensembl.org/id/ENSGALT00010051560.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030750.1", "url": "https://www.ensembl.org/id/ENSGALP00010030750.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419380", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419380", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AYY7-1", "protein_name": "Leucine-rich repeat-containing protein 47", "gene_name": "LRRC47", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAAAVSEPWPELDLAERERRRELLLTGPGLEQRVREAGGRLPPRLFTLPLLHYLEVSGCGSLREPGPGLAQGLPQLHSLVLRRNALGPGLTPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPSLPQLQSLNLSGNRLRELPADLARCAPRLQTLNLTGNRLDAFPAALFQPGALPLLSELAAADNCLRELSPGIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNQLRDKRLEKMVCGCQTRSILEYLRAGGRGCCRGRGRAEGPEKEEGRRKRRERRKRDSGEGEEAAVDEASRLLLRVLHVSENPAPLTVRASPEVKDVRPFIVGAVVRGMDLRPGNALKRFLSCQTKLHEDLCEKRTAATIATHDLRAIRGPLLYTARPPQDLKIVPLGRREVKAKDLVRQLQLEAEEHRKQKKRQNVSGLHRYLHLLDGQERYPCLLDADGDAISFPPITNSEKTKIKKTTCDLFLEVTSAASLQICKDILDALILKMAELNKYTLENKEESSLSDPEADAEAGPPSDARVAPTAEQDRRAPLVVEQVRVVDQDGQLKVVYPSKTDLDLAAAHVTVTR", "length": 583 }, "evidence": [ { "id": "A0A8V0ZJ00", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ00/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1LT49-1", "protein_name": "Leucine-rich repeat-containing protein 47", "gene_name": "Lrrc47", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "IIISGTRRKGAALRKRRTVGVMAAAMAVSEAWPELELAERERRRELLLTGPGLEERVKAAGGRLPPRLFTLPLLHYLEVSGCGSLRAPGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALETLPPGEGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRLRDKRLEKMVGGCQTKSILEYLRAGGRGGRSKGRQEGSEKEDRKKKRDRKQRRESGEGEEEVADSARLMLKVLHVSENPTPLTVRVSPEVRDVRPYIVGAVVRGMDLQPGNALRRFLNSQTKLHDDLCEKRTAATIATHDLQAVRGPLLYAARPPEDLKIVPLGRKEAKAKELVRQLQLEAEEQRKQKKRQSVSGLHRYLHLLDGKENYPCLVDAEGDVISFPPITNSEKTKIKRTTCSVFLEVTSATSLQLCKDIMDSLVLKMAELNKSTSENKEEDMLSGTETDASHGLSDPNLNPRAGKDGQCPLVVEQVRVVDLEGSLKVVYPSKADLVTLPPYVTVVR", "length": 601 }, "evidence": [ { "id": "A0A8V0ZJ00", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ00/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q505F5-1", "protein_name": "Leucine-rich repeat-containing protein 47", "gene_name": "Lrrc47", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAMAVSEAWPELELAERERRRELLLTGPGLEERVKAAGGRLPPRLFTLPLLHYLEVSGCGSLRAPGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALETLPPGEGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNRLDAFPPELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRLRDKRLEKMVGGCQTKSILEYLRAGGRGGRSKGRQEASEKEDRKKRRERKQHRESGEGEEEVADSARLMLKVLHVSENPTPLTVRVSPEVKDVRPYIVGAIVRGMDLQPGNALRRFLNSQTKLHDDLCEKRTAATIATHDLQAVRGPLLYAARPPEDLKIVPLGRKEAKAKELVRQLQLEAEEQRKQKKRQSVSGLHRYLHLLDGKENYPCLVDAEGDVISFPPITNSEKTKIKKTTCNLFLEVTSATSLQLCKDIMDSLILRMAELSKSTSENKEEDMLSGTEADAGCGLSDPNLTLSSGKDGQCPLVVEQVRVVDLEGSLKVVYPSKTDLITLPPHVTVVR", "length": 581 }, "evidence": [ { "id": "A0A8V0ZJ00", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ00/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N1G4-1", "protein_name": "Leucine-rich repeat-containing protein 47", "gene_name": "LRRC47", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAVSESWPELELAERERRRELLLTGPGLEERVRAAGGQLPPRLFTLPLLHYLEVSGCGSLRAPGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKLRDKRLEKMVSGCQTRSILEYLRVGGRGGGKGKGRAEGSEKEESRRKRRERKQRREGGDGEEQDVGDAGRLLLRVLHVSENPVPLTVRVSPEVRDVRPYIVGAVVRGMDLQPGNALKRFLTSQTKLHEDLCEKRTAATLATHELRAVKGPLLYCARPPQDLKIVPLGRKEAKAKELVRQLQLEAEEQRKQKKRQSVSGLHRYLHLLDGNENYPCLVDADGDVISFPPITNSEKTKVKKTTSDLFLEVTSATSLQICKDVMDALILKMAEMKKYTLENKEEGSLSDTEADAVSGQLPDPTTNPSAGKDGPSLLVVEQVRVVDLEGSLKVVYPSKADLATAPPHVTVVR", "length": 583 }, "evidence": [ { "id": "A0A8V0ZJ00", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ00/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ00" } ], "pmid": "" }, { "name": "phenylalanine-tRNA ligase activity", "id": "GO:0004826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004826", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phenylalanyl-tRNA aminoacylation", "id": "GO:0006432", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006432", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ00", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ00" }, { "id": "SM00873", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00873" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B3/B4 tRNA-binding", "eco_id": "ECO_0000259", "start_pos": 329, "end_pos": 505, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 428, "end_pos": 430 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJ14-1", "uniprot_ac": "A0A8V0ZJ14", "uniprot_id": "A0A8V0ZJ14_CHICK", "mass": { "chemical_mass": 229809.0, "monoisotopic_mass": 229809.0 }, "refseq": {}, "gene_names": [ { "name": "PLEKHG4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ14" } ] } ], "protein_names": [ { "name": "Pleckstrin homology and RhoGEF domain containing G4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ14/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ14", "locus": { "chromosome": "11", "start_pos": 1266992, "end_pos": 1348434, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021602", "url": "https://www.ensembl.org/id/ENSGALG00010021602" } ] } } ], "crossref": [ { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13242", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13242", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ09", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ14", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45845:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45845:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZJ09", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEWFAGSAGICWVQAALQVLDDSESLDGCIQSTLSALYPPFEATAATVLCQVFDVVEKTYRGDGLRYLIDFLIPAKHILQCIQQDACVQYCGLLFRHEGWPLCIHEKIVVQLASIDWRILKPGDFYLQVVPYLKKSPRIVLKCLAKDKHNVEEVVIPEVSYTSIFTLEWLSTINGERMGIALENCLLTTDDKIFRVPWDNVVNPEFINKPKITENNIITQETTGKPSLLCLPMDHAERSLPDVESQYRQEQSPNCNNLVVSSPAPQLGETLVNGVCSSPVPKEDLPSDLEGEYVELAEVSLPRFGPQTGSLTQSLALNYLTQPRTRVNASKGKHRFIVIQDSTYSKNLVHSALMQKEHCQMDTLSTSPEVLKNVIPLESNKTTACEELSPEGQLLSGGPGSMGNSFPAAAAPSCSAEDSCAAEQEAWSECSVDWQYAPCSNGDVCAGDGVSCKAQMTGSTGNMELESDGSSINPGVEILEQSPGANLDAAAEEEVMEEHREPLAEHQHEVTQVDPSLGSVLGPLGPCCTLKEGPHASCQSAGESTIPVHATALPATPESLAVGVERSSPSGNVTDAAAVRACADQETNYSCPVNPPEQLNGGEVGEIELGRRESPEDEEIEQVQAVKEHRSSCSCCSTNAPADGVLSDGEEQEVPACQHKRAEDAMLPQTALPAESGQVAEQSGTSGSLLGLDAQAEDSSQFGSHRSGERCGDPRGWTENQGNGSEMNSVLSPECVSAQDSQGGEENQDSFSDVDRTKAVALKTLESIQEELEVGPLSSGPAEGNIEPTALHSHPEAVPEASSPKGMVSDGAEVVKEVSGADVLKPAGKACALEETSTAVSPPRSPAPGAAWGGRSAPSIVKDVNPEVLRSGVACLPGTRDKSGRAVAIITTRNTAWLNPHCNTTELVRLLLYLHSIPRPECQALGLTVLVDARRCSPVPALFKAFSILQDMDPHCIHGVLLLVERDLTFRMEKPTAGQFEILTSMKSLHKHIDSSQLPLELDGTFPYCHRDWLSFRMKLEHLLQGCQGACAFLQGAIHRVESGKLPERAEEAAVLLRNYRQLMKNVLEDARLVRLQLEGGALLARLRKEESCVTLTQDYRDALDAAGVLYNQVDEGVHRLVMASNKRIQELELVMEFEKVEECFKEVSSWIENVGRRKLKEMINLDDSLEMLLQAQKQFREFDLVASEYCRRGQEALKKMDRWEDFSSVDVHSYRVKLQTYRDQLEEFCTQLDESRHRVCETVRLYEFFDKAYEWALEGMRHLACISMEECSSAEHCAGVIKCLESYKEQHPDISDARFQEMKELACELKSDKGLKQWKFAWSKCQETKLVFEKKLEAALRTRRALLSEQPQVGSEAGSVSHRRHSEGAAPGPQWDRTPGTSHSRPSRSTGWTKEKAPSPSLSCPGDFGAGEEFACQPALGAGPHVGRVAFGSGACKSPKLPEEKSNLESILETLEMKPSCASTPASGKLPPKRMLRKAQSFDLPCGESLWSGCQRTLSEPARYGNTGVFIKGLEVSSTELVDRTFALRQLEGQRGCGSAEARSWGSKLRHIIDEMVTTEREYVRSLCYIIESYFPEMERLDLPQDLRGKRSVIFGNLEKLYDFHSQYFLRELESCCNHPLRVSHCFLRHKDQFGMYALYSKNKPKSDSLLASHGNTFFKFKQVQLGDKMDLASYLLKPIQRMSKYALLLKDLIKECSEAQEQELGYLRAAEEMVKFQLRHGNDLLAMDAIRDCDVNLKEQGQLVRQDEFAIWLGRRKCQRHVFLFEDLILFSKPKRIEGGFDVYIYKRSFKTADIGLTENSGDSGLRFEIWFRRRKSSDTYILQASSAETKQAWTSDIAKILWQQAARNKEIRMQEMVSMGVGNKPFLDIKPSEAAINDRAIDYIMKGRAARTRASIAVSLFDHSNPYKRTQAQLSAGSTPAAYGPSSSSLLGPLNLHMYLDQALLPGVLAPRRPFDVSPCIEEDELEHETSSQPSLTTESSESSHCMSGSGSSGSDSGCVSSIPQESFCEDMGSPPFMPLGSQHSSAMEGKPRFTNSQYISAVSASSQSTLFALPVPTTASPVQGAASHVGTEDAAFGLGIAVGK", "length": 2089, "header": "tr|A0A8V0ZJ14-1|A0A8V0ZJ14_CHICK Isoform 1 of Pleckstrin homology and RhoGEF domain containing G4 OS=Gallus gallus OX=9031 GN=PLEKHG4 PE=4 SV=1 CANONICAL=A0A8V0ZJ14-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJ09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ14/entry#A0A8V0ZJ09-1", "sequence": { "sequence": "MGEWFAGSAGICWVQAALQVLDDSESLDGCIQSTLSALYPPFEATAATVLCQVFDVVEKTYRGDGLRYLIDFLIPAKHILQCIQQDACVQYCGLLFRHEGWPLCIHEKIVVQLASIDWRILKPGDFYLQVVPYLKKSPRIVLKCLAKDKHNVEEVVIPEVSYTSIFTLEWLSTINGERMGIALENCLLTTDDKIFRVPWDNVVNPEFINKPKITENNIITQETTGKPSLLCLPMDHAERSLPDVESQYRQEQSPNCNNLVVSSPAPQLGETLVNGVCSSPVPKEDLPSDLEGEYVELAEVSLPRFGPQTGSLTQSLALNYLTQPRTRVNASKGKHRFIVIQDSTYSKNLVHSALMQKEHCQMDTLSTSPEVLKNVIPLESNKTTACEELSPEGQLLSGGPGSMGNSFPAAAAPSCSAEDSCAAEQEAWSECSVDWQYAPCSNGDVCAGDGVSCKAQMTGSTGNMELESDGSSINPGVEILEQSPGANLDAAAEEEVMEEHREPLAEHQHEVTQVDPSLGSVLGPLGPCCTLKEGPHASCQSAGESTIPVHATALPATPESLAVGVERSSPSGNVTDAAAVRACADQETNYSCPVNPPEQLNGGEVGEIELGRRESPEDEEIEQVQAVKEHRSSCSCCSTNAPADGVLSDGEEQEVPACQHKRAEDAMLPQTALPAESGQVAEQSGTSGSLLGLDAQAEDSSQFGSHRSGERCGDPRGWTENQGNGSEMNSVLSPECVSAQDSQGGEENQDSFSDVDRTKAVALKTLESIQEELEVGPLSSGPAEGNIEPTALHSHPEAVPEASSPKGMVSDGAEVVKEVSGADVLKPAGKACALEETSTAVSPPRSPAPGAAWGGRSAPSIVKDVNPEVLRSGVACLPGTRDKSGRAVAIITTRNTAWLNPHCNTTELVRLLLYLHSIPRPECQALGLTVLVDARRCSPVPALFKAFSILQDMDPHCIHGVLLLVERDLTFRMEKPTAGQFEILTSMKSLHKHIDSSQLPLELDGTFPYCHRDWLSFRMKLEHLLQGCQGACAFLQGAIHRVESGKLPERAEEAAVLLRNYRQLMKNVLEDARLVRLQLEGGALLARLRKEESCVTLTQDYRDALDAAGVLYNQVDEGVHRLVMASNKRIQELELVMEFEKVEECFKEVSSWIENVGRRKLKEMINLDDSLEMLLQAQKQFREFDLVASEYCRRGQEALKKMDRWEDFSSVDVHSYRVKLQTYRDQLEEFCTQLDESRHRVCETVRLYEFFDKAYEWALEGMRHLACISMEECSSAEHCAGVIKCLESYKEQHPDISDARFQEMKELACELKSDKGLKQWKFAWSKCQETKLVFEKKLEAALRTRRALLSEQPQVGSEAGSVSHRRHSEGAAPGPQWDRTPGTSHSRPSRSTGWTKEKAPSPSLSCPGDFGAGEEFACQPALGAGPHVGRVAFGSGACKSPKLPEEKSNLESILETLEMKPSCASTPASGKLPPKRMLRKAQSFDLPCGESLWSGCQRTLSEPARYGNTGVFIKGLEVSSTELVDRTFALRQLEGQRGCGSAEARSWGSKLRHIIDEMVTTEREYVRSLCYIIESYFPEMERLDLPQDLRGKRSVIFGNLEKLYDFHSQYFLRELESCCNHPLRVSHCFLRHKDQFGMYALYSKNKPKSDSLLASHGNTFFKFKQVQLGDKMDLASYLLKPIQRMSKYALLLKDLIKECSEAQEQELGYLRAAEEMVKFQLRHGNDLLAMDAIRDCDVNLKEQGQLVRQDEFAIWLGRRKCQRHVFLFEDLILFSKPKRIEGGFDVYIYKRSFKTADIGLTENSGDSGLRFEIWFRRRKSSDTYILQASSAETKQAWTSDIAKILWQQAARNKEIRMQEMVSMGVGNKPFLDIKPSEAAINDRAIDYIMKGRAARTRASIAVSLFDHSNPYKRTQAQLSAGSTPAAYGPSSSSLLGPLNLHMYLDQALLPGVLAPRRPFDVSPCIEEDELEHETSSQPSLTTESSESSHCMSGSGSSGSDSGCVSSIPQESFCEDMGSPPFMPLGSQHSSAMEGKPRFTNSQYISAKAGQATISPSTIV", "length": 2059, "header": "tr|A0A8V0ZJ09-1|A0A8V0ZJ14_CHICK Computationally mapped isoform of Pleckstrin homology and RhoGEF domain containing G4 OS=Gallus gallus OX=9031 GN=PLEKHG4 PE=4 SV=1 CANONICAL=A0A8V0ZJ14-1" }, "locus": { "chromosome": "11", "start_pos": 1348235, "end_pos": 1269263, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052440.1", "url": "https://www.ensembl.org/id/ENSGALT00010052440.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031347.1", "url": "https://www.ensembl.org/id/ENSGALP00010031347.1" } ] } }, { "isoform_ac": "A0A8V0ZJ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ14/entry#A0A8V0ZJ14-1", "sequence": { "sequence": "MGEWFAGSAGICWVQAALQVLDDSESLDGCIQSTLSALYPPFEATAATVLCQVFDVVEKTYRGDGLRYLIDFLIPAKHILQCIQQDACVQYCGLLFRHEGWPLCIHEKIVVQLASIDWRILKPGDFYLQVVPYLKKSPRIVLKCLAKDKHNVEEVVIPEVSYTSIFTLEWLSTINGERMGIALENCLLTTDDKIFRVPWDNVVNPEFINKPKITENNIITQETTGKPSLLCLPMDHAERSLPDVESQYRQEQSPNCNNLVVSSPAPQLGETLVNGVCSSPVPKEDLPSDLEGEYVELAEVSLPRFGPQTGSLTQSLALNYLTQPRTRVNASKGKHRFIVIQDSTYSKNLVHSALMQKEHCQMDTLSTSPEVLKNVIPLESNKTTACEELSPEGQLLSGGPGSMGNSFPAAAAPSCSAEDSCAAEQEAWSECSVDWQYAPCSNGDVCAGDGVSCKAQMTGSTGNMELESDGSSINPGVEILEQSPGANLDAAAEEEVMEEHREPLAEHQHEVTQVDPSLGSVLGPLGPCCTLKEGPHASCQSAGESTIPVHATALPATPESLAVGVERSSPSGNVTDAAAVRACADQETNYSCPVNPPEQLNGGEVGEIELGRRESPEDEEIEQVQAVKEHRSSCSCCSTNAPADGVLSDGEEQEVPACQHKRAEDAMLPQTALPAESGQVAEQSGTSGSLLGLDAQAEDSSQFGSHRSGERCGDPRGWTENQGNGSEMNSVLSPECVSAQDSQGGEENQDSFSDVDRTKAVALKTLESIQEELEVGPLSSGPAEGNIEPTALHSHPEAVPEASSPKGMVSDGAEVVKEVSGADVLKPAGKACALEETSTAVSPPRSPAPGAAWGGRSAPSIVKDVNPEVLRSGVACLPGTRDKSGRAVAIITTRNTAWLNPHCNTTELVRLLLYLHSIPRPECQALGLTVLVDARRCSPVPALFKAFSILQDMDPHCIHGVLLLVERDLTFRMEKPTAGQFEILTSMKSLHKHIDSSQLPLELDGTFPYCHRDWLSFRMKLEHLLQGCQGACAFLQGAIHRVESGKLPERAEEAAVLLRNYRQLMKNVLEDARLVRLQLEGGALLARLRKEESCVTLTQDYRDALDAAGVLYNQVDEGVHRLVMASNKRIQELELVMEFEKVEECFKEVSSWIENVGRRKLKEMINLDDSLEMLLQAQKQFREFDLVASEYCRRGQEALKKMDRWEDFSSVDVHSYRVKLQTYRDQLEEFCTQLDESRHRVCETVRLYEFFDKAYEWALEGMRHLACISMEECSSAEHCAGVIKCLESYKEQHPDISDARFQEMKELACELKSDKGLKQWKFAWSKCQETKLVFEKKLEAALRTRRALLSEQPQVGSEAGSVSHRRHSEGAAPGPQWDRTPGTSHSRPSRSTGWTKEKAPSPSLSCPGDFGAGEEFACQPALGAGPHVGRVAFGSGACKSPKLPEEKSNLESILETLEMKPSCASTPASGKLPPKRMLRKAQSFDLPCGESLWSGCQRTLSEPARYGNTGVFIKGLEVSSTELVDRTFALRQLEGQRGCGSAEARSWGSKLRHIIDEMVTTEREYVRSLCYIIESYFPEMERLDLPQDLRGKRSVIFGNLEKLYDFHSQYFLRELESCCNHPLRVSHCFLRHKDQFGMYALYSKNKPKSDSLLASHGNTFFKFKQVQLGDKMDLASYLLKPIQRMSKYALLLKDLIKECSEAQEQELGYLRAAEEMVKFQLRHGNDLLAMDAIRDCDVNLKEQGQLVRQDEFAIWLGRRKCQRHVFLFEDLILFSKPKRIEGGFDVYIYKRSFKTADIGLTENSGDSGLRFEIWFRRRKSSDTYILQASSAETKQAWTSDIAKILWQQAARNKEIRMQEMVSMGVGNKPFLDIKPSEAAINDRAIDYIMKGRAARTRASIAVSLFDHSNPYKRTQAQLSAGSTPAAYGPSSSSLLGPLNLHMYLDQALLPGVLAPRRPFDVSPCIEEDELEHETSSQPSLTTESSESSHCMSGSGSSGSDSGCVSSIPQESFCEDMGSPPFMPLGSQHSSAMEGKPRFTNSQYISAVSASSQSTLFALPVPTTASPVQGAASHVGTEDAAFGLGIAVGK", "length": 2089, "header": "tr|A0A8V0ZJ14-1|A0A8V0ZJ14_CHICK Isoform 1 of Pleckstrin homology and RhoGEF domain containing G4 OS=Gallus gallus OX=9031 GN=PLEKHG4 PE=4 SV=1 CANONICAL=A0A8V0ZJ14-1" }, "locus": { "chromosome": "11", "start_pos": 1348235, "end_pos": 1269700, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052445.1", "url": "https://www.ensembl.org/id/ENSGALT00010052445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031352.1", "url": "https://www.ensembl.org/id/ENSGALP00010031352.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1466, "start_aa": "Thr", "end_pos": 1466, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1466", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1923, "start_aa": "Thr", "end_pos": 1923, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1923", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 589, "end_pos": 591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" }, { "start_pos": 904, "end_pos": 906, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ14" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 1550, "end_pos": 1727, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ14" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 1739, "end_pos": 1846, "start_aa": "Asn", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1466, 1923 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 329, "end_pos": 331 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 589, "end_pos": 591 }, { "start_pos": 724, "end_pos": 726 }, { "start_pos": 904, "end_pos": 906 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJ48-1", "uniprot_ac": "A0A8V0ZJ48", "uniprot_id": "A0A8V0ZJ48_CHICK", "mass": { "chemical_mass": 29869.0, "monoisotopic_mass": 29869.0 }, "refseq": { "ac": "XP_004941326", "name": "leucine-rich repeat-containing protein 10B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941326" }, "gene_names": [ { "name": "LRRC10B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ48" } ] }, { "name": "LRRC10B", "type": "synonym", "evidence": [ { "id": "XP_004941326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941326" } ] } ], "protein_names": [ { "name": "Succinate dehydrogenase complex assembly factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJ48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ48/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 10B", "type": "synonym", "evidence": [ { "id": "XP_004941326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941326" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004941326.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941326" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ48" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC10B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ48", "locus": {} } ], "crossref": [ { "id": "430454", "url": "https://www.ncbi.nlm.nih.gov/gene/430454", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YDHNPVR", "url": "https://omabrowser.org/oma/group/YDHNPVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ48", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004941326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941326", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSGGSTCLISAEGPAGVEQRLEARRGRLPPALWAQRGLRKLYLSGAGLRDVPAELASLRHLRTLALDGNELMEVPEALCQLPCLAYLYLGRNGLQGLPPAFGHLQSLRCLWLEGNFMGRFPTALLGLPGLRSLQLGDNRLARLPSSLPRMAGLQGLWLYGNRFQHFPPVLLRMAQLRVLDLDRNRIARFPDLRGLAGLCLLSYDHNPVPQPPRVADTVRLVGSGAVEYMEEREERLREQQRLEEEEEEEEGAGRMPRDDGSPLLEDAP", "length": 269, "header": "tr|A0A8V0ZJ48-1|A0A8V0ZJ48_CHICK Isoform 1 of Succinate dehydrogenase complex assembly factor 2 OS=Gallus gallus OX=9031 GN=LRRC10B PE=4 SV=1 CANONICAL=A0A8V0ZJ48-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJ48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ48/entry#A0A8V0ZJ48-1", "sequence": { "sequence": "MGSGGSTCLISAEGPAGVEQRLEARRGRLPPALWAQRGLRKLYLSGAGLRDVPAELASLRHLRTLALDGNELMEVPEALCQLPCLAYLYLGRNGLQGLPPAFGHLQSLRCLWLEGNFMGRFPTALLGLPGLRSLQLGDNRLARLPSSLPRMAGLQGLWLYGNRFQHFPPVLLRMAQLRVLDLDRNRIARFPDLRGLAGLCLLSYDHNPVPQPPRVADTVRLVGSGAVEYMEEREERLREQQRLEEEEEEEEGAGRMPRDDGSPLLEDAP", "length": 269, "header": "tr|A0A8V0ZJ48-1|A0A8V0ZJ48_CHICK Isoform 1 of Succinate dehydrogenase complex assembly factor 2 OS=Gallus gallus OX=9031 GN=LRRC10B PE=4 SV=1 CANONICAL=A0A8V0ZJ48-1" }, "locus": { "chromosome": "5", "start_pos": 307853, "end_pos": 307047, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048532.1", "url": "https://www.ensembl.org/id/ENSGALT00010048532.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028623.1", "url": "https://www.ensembl.org/id/ENSGALP00010028623.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZED9-1", "protein_name": "Leucine rich repeat containing 10B", "gene_name": "Lrrc10b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGIAESTPDELPSDAEEQLRSGEQQLELSGRRLRRLPSAVCALSRLQKLYVSGTGLRELPEEIEELRELRILALDFNKLERLPDGLCRLPRLTRLYLGGNRLLALPSDFAQLQSLRCLWIEGNFLRRFPRPLLRLVALQSLQMGDNRLRALPAELPRMTGLRGLWLYGNRFEEFPPALLRMGRLHILDLDRNRLGGFPDLHPLRALRVFSYDHNPVTGPPRVADTVFLVGEGAVERMAERDEPIPRPPARRPARAFDDEEEEDLLIGSAGPRALGPARDNLRALEAPPGLGT", "length": 292 }, "evidence": [ { "id": "A0A8V0ZJ48", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ48/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RIE9-1", "protein_name": "Leucine rich repeat containing 10B", "gene_name": "LRRC10B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGIAESTPDELPSDAEEQLRNGEQQLELSGRRLRRLPSAVCALSRLQKLYVSGTGLRELPEEIEELRELRILALDFNKLERLPDGLCRLPRLTRLYLGGNRLLALPADFAQLQSLRCLWIEGNFLRRFPRPLLRLVALQSLQMGDNRLRALPAELPRMTGLRGLWLYGNRFEEFPPALLRMGRLHILDLDRNRLGGFPDLHPLRALRVFSYDHNPVTGPPRVADTVFLVGEGAVERMAERDEPTPRPPPRRPVRTFEDEEEEDLLIGGGGSRALGPPRAASTPWKQLQDWAPEPVLRG", "length": 298 }, "evidence": [ { "id": "A0A8V0ZJ48", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ48/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3N1L1-1", "protein_name": "Leucine rich repeat containing 10B", "gene_name": "LRRC10B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGIAESTPDELPSDAEEQLRNGEQQLELSGRRLRRLPSAVCALSRLQKLYVSGTGLRELPEEIEELRELRILALDFNKLERLPDGLCRLPRLTRLYLGSNRLLALPADFAQLQSLRCLWIEGNFLRRFPRPLLRLVALQSLQMGDNRLRALPAELPRMTGLRGLWLYGNRFEEFPPALLRMGRLHILDLDRNRLGGFPDLHPLRALRVFSYDHNPVTGPPRVADTVFLVGEGAVERMAERDEPTPRPPPRRPARVFDDEEEEDLLIGGGSSQALGAPGDSLRALEAAPGLGT", "length": 292 }, "evidence": [ { "id": "A0A8V0ZJ48", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ48/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3XA50-1", "protein_name": "Leucine rich repeat containing 10B", "gene_name": "Lrrc10b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGIAESTPDELPSDAEEQLRSGEQQLELSGRRLRRLPSAVCALSRLQKLYVSGTGLRELPEEIEELRELRILALDFNKLERLPDGLCRLPRLTRLYLGGNRLLALPPDFAQLQSLRCLWIEGNFLRRFPRPLLRLVALQSLQMGDNRLRALPAELPRMTGLRGLWLYGNRFEEFPPALLRMGRLHILDLDRNRLGGFPDLHPLRALRVFSYDHNPVTGPPRVADTVFLVGEGAVERMAERDEPIPRQPARRPTRAFDDEEEEDLLIGGAGPRALGPTRDSLRALEAPPGLGT", "length": 292 }, "evidence": [ { "id": "A0A8V0ZJ48", "url": "https://omabrowser.org/oma/group/A0A8V0ZJ48/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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}, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJ57-1", "uniprot_ac": "A0A8V0ZJ57", "uniprot_id": "A0A8V0ZJ57_CHICK", "mass": { "chemical_mass": 55350.0, "monoisotopic_mass": 55350.0 }, "refseq": {}, "gene_names": [ { "name": "ASIC2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ57" } ] } ], "protein_names": [ { "name": "Acid sensing ion channel subunit 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ57/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ57" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASIC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ57", "locus": { "chromosome": "27", "start_pos": 1419664, "end_pos": 1497163, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022691", "url": "https://www.ensembl.org/id/ENSGALG00010022691" } ] } } ], "crossref": [ { "id": "A0A8V0ZJ57", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJ57", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ57", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11690:SF128", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11690:SF128", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZJ57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ57-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSRRAALPRRALWVLAFCTALGLLLSWSSNRLLHWLSFPSHTQVRTEWSRQLAFPAVTLCNNNPLRFPRLSKGDLYYAGHWLGLLLPNRTARPLLTELLRGDEARLRWFAKLADFRLFLPPRHYEGISADFMDRLGHQLEDMLLSCKYRGELCGPHNFSAVFTKYGKCYMFNSGEEGRPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFVQELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSDMGLDFFPVYSITACRIDCETRYIVENCNCKMVHMPGDAPFCTPEQYKECAEPALGLLAEKDSNYCICRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYIYELIKEKLLDLLGKEEEEGSHDENVSTCDPMPNHSETISHTVNVPLQATLGTLEEIAC", "length": 488, "header": "tr|A0A8V0ZJ57-1|A0A8V0ZJ57_CHICK Isoform 1 of Acid sensing ion channel subunit 2 OS=Gallus gallus OX=9031 GN=ASIC2 PE=4 SV=1 CANONICAL=A0A8V0ZJ57-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJ57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ57/entry#A0A8V0ZJ57-1", "sequence": { "sequence": "MCSRRAALPRRALWVLAFCTALGLLLSWSSNRLLHWLSFPSHTQVRTEWSRQLAFPAVTLCNNNPLRFPRLSKGDLYYAGHWLGLLLPNRTARPLLTELLRGDEARLRWFAKLADFRLFLPPRHYEGISADFMDRLGHQLEDMLLSCKYRGELCGPHNFSAVFTKYGKCYMFNSGEEGRPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFVQELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSDMGLDFFPVYSITACRIDCETRYIVENCNCKMVHMPGDAPFCTPEQYKECAEPALGLLAEKDSNYCICRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYIYELIKEKLLDLLGKEEEEGSHDENVSTCDPMPNHSETISHTVNVPLQATLGTLEEIAC", "length": 488, "header": "tr|A0A8V0ZJ57-1|A0A8V0ZJ57_CHICK Isoform 1 of Acid sensing ion channel subunit 2 OS=Gallus gallus OX=9031 GN=ASIC2 PE=4 SV=1 CANONICAL=A0A8V0ZJ57-1" }, "locus": { "chromosome": "27", "start_pos": 1497137, "end_pos": 1420230, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055185.1", "url": "https://www.ensembl.org/id/ENSGALT00010055185.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033388.1", "url": "https://www.ensembl.org/id/ENSGALP00010033388.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ57" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ57" } ], "pmid": "" }, { "name": "sensory perception of sour taste", "id": "GO:0050915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ57" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "pH-gated sodium channel activity", "id": "GO:0160125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJ57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": 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This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015152142.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152142", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152142" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CABLES2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJB2", "locus": { "chromosome": "20", "start_pos": 8281178, "end_pos": 8298661, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021350", "url": "https://www.ensembl.org/id/ENSGALG00010021350" } ] } } ], "crossref": [ { "id": "A0A8V0ZJB2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJB2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20603", 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"length": 1068, "header": "tr|A0A8V0ZJF4-1|A0A8V0ZJF4_CHICK Isoform 1 of Pleckstrin homology and RhoGEF domain containing G3 OS=Gallus gallus OX=9031 GN=PLEKHG3 PE=4 SV=1 CANONICAL=A0A8V0ZJF4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF4/entry#A0A8V0ZJD9-1", "sequence": { "sequence": "MPVPALGAGPDPGMEEEAASGDGTEPWLANSNNNAAPVGWPCRRGEEPSYLQRVLLEIVESERTYARDLRGIVEGYLGKIIDAQEPPLRPEQVSALFGNIEDIYELSSNLLQSLESCACDPVAVAVCFVTRSQEFDIYTQYCNNYPNSVATLSECMRSKQQARFFRECQEEMRHVLPLGAYLLKPVQRILKYHLLLQEIAKHFEHKSGDDYEVVVEAIDTMTCVAWYINDMKRKHEHAIRQQEIQSLLLQWKGPDLTTYGELVLEGSFRAQRARSERAVFLFDKLLLITKRRGDHYVYKSHIPCASLMLIESTRDSLGHGVYGVGGLGAPAHLMLPLPPPQAKSAEEKRVWTHHIKRLILENHHAIVPQKVRAHTPVSPHFCPGVGDILRCHPLPLTDPRLLPPARPRRPSWRWTCSPNAPDHPSRPPLSPRPPHCPHTPSSLRYPCRPPTPAPLQP", "length": 457, "header": "tr|A0A8V0ZJD9-1|A0A8V0ZJF4_CHICK Computationally mapped isoform of Pleckstrin homology and RhoGEF domain containing G3 OS=Gallus gallus OX=9031 GN=PLEKHG3 PE=4 SV=1 CANONICAL=A0A8V0ZJF4-1" }, "locus": { "chromosome": "5", "start_pos": 559944, "end_pos": 556388, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052570.1", "url": "https://www.ensembl.org/id/ENSGALT00010052570.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031476.1", "url": "https://www.ensembl.org/id/ENSGALP00010031476.1" } ] } }, { "isoform_ac": "A0A8V0ZJF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF4/entry#A0A8V0ZJF4-1", "sequence": { "sequence": "MGLGSRGVGTRGPYGAWGLWRRPSGQPGWYAPQSPGMPVPALGAGPDPGMEEEAASGDGTEPWLANSNNNAAPVGWPCRRGEEPSYLQRVLLEIVESERTYARDLRGIVEGYLGKIIDAQEPPLRPEQVSALFGNIEDIYELSSNLLQSLESCACDPVAVAVCFVTRSQEFDIYTQYCNNYPNSVATLSECMRSKQQARFFRECQEEMRHVLPLGAYLLKPVQRILKYHLLLQEIAKHFEHKSGDDYEVVVEAIDTMTCVAWYINDMKRKHEHAIRQQEIQSLLLQWKGPDLTTYGELVLEGSFRAQRARSERAVFLFDKLLLITKRRGDHYVYKSHIPCASLMLIESTRDSLCFSVAHYKHIKQQYALQAKSAEEKRVWTHHIKRLILENHHAIVPQKAKEAILEMDLFCECPRVPRCPLVRLGGGGLPPGVSVPQVGAKPLPPSPLAQHAGSEGTLLDAGEPLQPPRSWAEGVVEEEEEEEEEALHKDSHEDGDRDKNGDVAEKPQEKQVSSPPLGWPASLKGHAPSAVETHEWHQEAAATPVSPASPPCHVEHEGLGTPAPPSPSGSLPPAGLSEEEEEEEEEGHGGGSILPPSVLDQASVIAERFGSSMSRRGSVVLDGRGGSALSLDGVTPPQENMGSCSPLPSPGSPQGCRRRSLLSTQDRLLLRKIRSYYEHAEHQDAAFSIRRRESLSYIPKGLVRNSVSRINSWPPPEPGSPKTPPEPVSPKALLEPESPKSSPEPGSPKTSLEAASPQVSPAPDGGASPPVCRENGLPEPPAEPLLILEEEEVPPPGVLAAGAPPRRLTSRVYQLARQYSLRIKSRRRAVAAPGDAASHTPAPGGMRWGTAGIVPLPPPRSHPAPSTPGVPKLPVSPRDGVTVPAPRSPPSPNGAAAEAFSWPDVRELRARFGAPRPPPVTRSRSAPEGPERGGRPAAKEQQGGGRSRSAEAGTGTPNVLRGDDHQHAAAGLWVTAQAPLGPGGQRVLVLERLPPAVAAEPPTYVQIRSPTTREKICLKAVVERCKAYQASEEYRQRCAHGQAEAPEPPRHGLVRDLRQKFQTLDAAS", "length": 1068, "header": "tr|A0A8V0ZJF4-1|A0A8V0ZJF4_CHICK Isoform 1 of Pleckstrin homology and RhoGEF domain containing G3 OS=Gallus gallus OX=9031 GN=PLEKHG3 PE=4 SV=1 CANONICAL=A0A8V0ZJF4-1" }, "locus": { "chromosome": "5", "start_pos": 560999, "end_pos": 553994, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052585.1", "url": "https://www.ensembl.org/id/ENSGALT00010052585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031491.1", "url": "https://www.ensembl.org/id/ENSGALP00010031491.1" } ] } }, { "isoform_ac": "A0A8V0ZJG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF4/entry#A0A8V0ZJG0-1", "sequence": { "sequence": "MPVPALGAGPDPGMEEEAASGDGTEPWLANSNNNAAPVGWPCRRGEEPSYLQRVLLEIVESERTYARDLRGIVEGYLGKIIDAQEPPLRPEQVSALFGNIEDIYELSSNLLQSLESCACDPVAVAVCFVTRSQEFDIYTQYCNNYPNSVATLSECMRSKQQARFFRECQEEMRHVLPLGAYLLKPVQRILKYHLLLQEIAKHFEHKSGDDYEVVVEAIDTMTCVAWYINDMKRKHEHAIRQQEIQSLLLQWKGPDLTTYGELVLEGSFRAQRARSERAVFLFDKLLLITKRRGDHYVYKSHIPCASLMLIESTRDSLCFSVAHYKHIKQQYALQAKSAEEKRVWTHHIKRLILENHHAIVPQKPAKQILQQLGGMKVRLGGGGLPPGVSVPQVGAKPLPPSPLAQHAGSEGTLLDAGEPLQPPRSWAEGVVEEEEEEEEEALHKDSHEDGDRDKNGDVAEKPQEKQVSSPPLGWPASLKGHAPSAGLGTPAPPSPSGSLPPAGLPDEEEQHPETGTGEDPRALSSEEEEEEEEEGHGGGSILPPSVLDQASVIAERFGSSMSRRGSVVLDGRGGSALSLDGVTPPQENMGSCSPLPSPGSPQGCRRRSLLSTQDRLLLRKIRSYYEHAEHQDAAFSIRRRESLSYIPKGLVRNSVSRINSWPPPEPGSPKTPPEPVSPKALLEPESPKSSPEPGSPKTSLEAASPQVSPAPDGGASPPVCRENGLPEPPAEPLLILEEEEVPPPGVLAAGAPPRRLTSRVYQLARQYSLRIKSRRRAVAAPGDAASHTPAPGGMRWGTAGIVPLPPPRSHPAPSTPGVPKLPVSPRDGVTVPAPRSPPSPNGAAAEAFSWPDVRELRARFGAPRPPPVTRSRSAPEGPERGGRPAAKEQQGGGRSRSAEAGTGTPNVLRGDDHQHAAAGLWVTAQAPLGPGGQRVLVLERLPPAVAAEPPTYVQIRSPTTREKICLKAVVERCKAYQASEEYRQRCAHGQAEAPEPPRHGLVRDLRQKFQTLDAAS", "length": 1016, "header": "tr|A0A8V0ZJG0-1|A0A8V0ZJG0_CHICK Computationally mapped isoform of Pleckstrin homology and RhoGEF domain containing G3 OS=Gallus gallus OX=9031 GN=PLEKHG3 PE=4 SV=1 CANONICAL=A0A8V0ZJF4-1" }, "locus": { "chromosome": "5", "start_pos": 559944, "end_pos": 553994, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052590.1", "url": "https://www.ensembl.org/id/ENSGALT00010052590.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031496.1", "url": "https://www.ensembl.org/id/ENSGALP00010031496.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 867, "start_aa": "Thr", "end_pos": 867, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr867", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-GGA-9013408", "name": "", "url": 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33483.0, "monoisotopic_mass": 33483.0 }, "refseq": { "ac": "XP_001235224", "name": "potassium channel subfamily K member 16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235224" }, "gene_names": [ { "name": "KCNK16", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF1" } ] }, { "name": "KCNK16", "type": "synonym", "evidence": [ { "id": "XP_001235224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235224" } ] } ], "protein_names": [ { "name": "2P domain potassium channel Talk-1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF1/entry#names_and_taxonomy" } ] }, { "name": "TWIK-related alkaline pH-activated K(+) channel 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF1/entry#names_and_taxonomy" } ] }, { "name": "potassium channel subfamily K member 16", "type": "synonym", "evidence": [ { "id": "XP_001235224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235224" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001235224.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001235224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001235224" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNK16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF1", "locus": { "chromosome": "3", "start_pos": 28782829, "end_pos": 28774685, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020134", "url": "https://www.ensembl.org/id/ENSGALG00010020134" } ] } } ], "crossref": [ { "id": "A0A8V0ZJF1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "772022", 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"database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78547", "url": "https://www.rhea-db.org/rhea/78547", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78555", "url": "https://www.rhea-db.org/rhea/78555", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZJF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFLTAPNWQISWTPLLVLGYLFYLLLGAMVFQLLEKQAETHSRDQFHLEKLKFLQNYRCLDRQALEQFIQVLMEAWEKGVNPERNSTNPSNWDFSNSFFFAGTVVTTIGYGNRSPSTVAGQVFCVFYALFGVPLNLAFLNQLGKGLNAHLITLERWVQKPGHDQVVQRLAVAVFLTAGTLLFLVFPPLVFCYVEGWSYGEGFYFTFITLSTIGFGDYVVGANPNKHYIPLYRSLTAIWIVFGLAWLALVFNVGADLMEKFLQLKWHKPDLSLSEGAPTKLEDEPEQPRIHIPT", "length": 294, "header": "tr|A0A8V0ZJF1-1|A0A8V0ZJF1_CHICK Isoform 1 of 2P domain potassium channel Talk-1 OS=Gallus gallus OX=9031 GN=KCNK16 PE=3 SV=1 CANONICAL=A0A8V0ZJF1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF1/entry#A0A8V0ZJF1-1", "sequence": { "sequence": "MPFLTAPNWQISWTPLLVLGYLFYLLLGAMVFQLLEKQAETHSRDQFHLEKLKFLQNYRCLDRQALEQFIQVLMEAWEKGVNPERNSTNPSNWDFSNSFFFAGTVVTTIGYGNRSPSTVAGQVFCVFYALFGVPLNLAFLNQLGKGLNAHLITLERWVQKPGHDQVVQRLAVAVFLTAGTLLFLVFPPLVFCYVEGWSYGEGFYFTFITLSTIGFGDYVVGANPNKHYIPLYRSLTAIWIVFGLAWLALVFNVGADLMEKFLQLKWHKPDLSLSEGAPTKLEDEPEQPRIHIPT", "length": 294, "header": "tr|A0A8V0ZJF1-1|A0A8V0ZJF1_CHICK Isoform 1 of 2P domain potassium channel Talk-1 OS=Gallus gallus OX=9031 GN=KCNK16 PE=3 SV=1 CANONICAL=A0A8V0ZJF1-1" }, "locus": { "chromosome": "3", "start_pos": 28782586, "end_pos": 28775472, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048637.1", "url": "https://www.ensembl.org/id/ENSGALT00010048637.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028728.1", "url": "https://www.ensembl.org/id/ENSGALP00010028728.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 86, "start_aa": "Asn", "end_pos": 86, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn86", "evidence": [ { "id": "A0A8V0ZJF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJF1#ptm_processing" }, { "id": "PIRSR038061-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR038061-1" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:772022", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:772022", "resource": 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"https://omabrowser.org/oma/group/A0A8V0ZJF1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3L7IMU8-1", "protein_name": "2P domain potassium channel Talk-1", "gene_name": "Kcnk16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPRAGLCSCWGGQVLPLLLAYICYLLLGATIFQLLEKQAEAQSRDQFQLEKLRFLENYTCLDQQALEQFVQVILEARVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNHLGTGLRAHLTTLDRWEDHPRHSQLLQVLGLALFLTLGTLVILIFPPMFFSHVEGWSFREGFYFAFITLSTIGFGDYVVGTDPSKHYIAVYRSLAAIWILLGLAWLAVVLSLGSLLLHRCSRLWLLIRGLDLKDGADPDSDPRPQKIPISA", "length": 292 }, "evidence": [ { "id": "A0A8V0ZJF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJF1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZLR9-1", "protein_name": "2P domain potassium channel Talk-1", "gene_name": "Kcnk16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRAGVCSCWGGQVLPLLLAYICYLLLGATIFQRLEKQAEAQSRDQFQLEKLRFLENYTCLDQQALEQFVQVILEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNHLGTGLRAHLTTLDRWEDHPRHSQLLQVLGLALFLTLGTLVILIFPPMFFSHVEGWSFREGFYFAFITLSTIGFGDYVVGTDPSKHYIAVYRSLAAIWILLGLAWLAVVLSLGSLLLHRCSRLWQLIRGLDVKDGAAPGSEPRSQKIPFSA", "length": 292 }, "evidence": [ { "id": "A0A8V0ZJF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJF1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BEH1-1", "protein_name": "2P domain potassium channel Talk-1", "gene_name": "KCNK16", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPRTGLCSRWGGRVLPLLLAYICYLLLGATIFQLLEKQAESQSRDRFQFEKLRFLENYTCLDQQAVEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALVGIPLNVVFLNHLGTGLRAHLTMLERWEDQHRRSQLLQTLGLALFLALGTLLILILPPMIFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYLSVYRSLAAIWILLGLAWLALVLPLGPLLLHRCSQLWLLGRGLGLKEGGAPETNGLPRPQKIPISA", "length": 294 }, "evidence": [ { "id": "A0A8V0ZJF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJF1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G5E845-1", "protein_name": "Potassium channel, subfamily K, member 16", "gene_name": "Kcnk16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRAGVCGCWGGQVLPLLLAYICYLLLGATIFQLLEKQAEAQSRDQFQLEKLRFLENYTCLDQQALEQFVQVILEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNHLGTGLRAHLTTLDRWEDHPRHSQLLQVLGLALFLTLGTLVILIFPPMFFSHVEGWSFREGFYFAFITLSTIGFGDYVVGTDPSKHYIAVYRSLAAIWILLGLAWLAVVLSLGSLLLHRCSRLWQLIRGLDLKDGAAPDSEPRSQKIPISA", "length": 292 }, "evidence": [ { "id": "A0A8V0ZJF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZJF1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96T55-1", "protein_name": "Potassium channel subfamily K member 16", "gene_name": "KCNK16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { 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This record is derived from a genomic sequence (NC_052579.1) annotated using gene prediction method: Gnomon, supported by EST evidence. 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COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004944672", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004944672" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZJG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "416045", "url": "https://www.ncbi.nlm.nih.gov/gene/416045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037660", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZJG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPMKYKSSVSSVSCGLQYHHALIKQSQKMNVHLVRTYCAPGPKRPEGKSAIETAVGILNRVAEAGAVVGKNSLQKISATGKNWWDKYEEFVGLNEVREAQGKVTEAENVFMIARGIVRQARENVEAQQIKLKEVRDRLDRVSRDDTQYLELATLEHRLLQEEKRYRAAYLNAEESEREKFSLFSAAVRESHEKERTRAEKTKNWSIIGSVLGAIIGVLGSTYVNRVRLQELKVLVLEAQKAPINLQEAIKEQASTYDLQQKDLSDVIADLKNILQTKTSQGTKEGVSLAREDRSDSIKIDSLLIPLKEQLNYTKQVSSCLGSLQQQFTRLQESVAQIISEVQSVKLAVHSRPMDRVTARSSGESKGQASAVRDVILELCDTERRLESQIKRNSIYSTALTCTVFAVSLPVLYILLKGN", "length": 419, "header": "tr|A0A8V0ZJG3-1|A0A8V0ZJG3_CHICK Isoform 1 of Coiled-coil domain containing 51 OS=Gallus gallus OX=9031 GN=CCDC51 PE=1 SV=1 CANONICAL=A0A8V0ZJG3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJG3/entry#A0A8V0ZJG3-1", "sequence": { "sequence": "MGPMKYKSSVSSVSCGLQYHHALIKQSQKMNVHLVRTYCAPGPKRPEGKSAIETAVGILNRVAEAGAVVGKNSLQKISATGKNWWDKYEEFVGLNEVREAQGKVTEAENVFMIARGIVRQARENVEAQQIKLKEVRDRLDRVSRDDTQYLELATLEHRLLQEEKRYRAAYLNAEESEREKFSLFSAAVRESHEKERTRAEKTKNWSIIGSVLGAIIGVLGSTYVNRVRLQELKVLVLEAQKAPINLQEAIKEQASTYDLQQKDLSDVIADLKNILQTKTSQGTKEGVSLAREDRSDSIKIDSLLIPLKEQLNYTKQVSSCLGSLQQQFTRLQESVAQIISEVQSVKLAVHSRPMDRVTARSSGESKGQASAVRDVILELCDTERRLESQIKRNSIYSTALTCTVFAVSLPVLYILLKGN", "length": 419, "header": "tr|A0A8V0ZJG3-1|A0A8V0ZJG3_CHICK Isoform 1 of Coiled-coil domain containing 51 OS=Gallus gallus OX=9031 GN=CCDC51 PE=1 SV=1 CANONICAL=A0A8V0ZJG3-1" }, "locus": { "chromosome": "12", "start_pos": 11452878, "end_pos": 11449754, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051855.1", "url": "https://www.ensembl.org/id/ENSGALT00010051855.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030936.1", "url": "https://www.ensembl.org/id/ENSGALP00010030936.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416045", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QRW6-1", "protein_name": "Mitochondrial potassium channel", "gene_name": "ccdc51", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRFRTNTVFPGSFVSTCLYRHQGFNPVQWSLHRSYCTQQQSPKDEPNKTTSAKERTASALAYAGELGKQWGRNAVKTTSVTVNYWWERYEEFVGLNEVRDAQSKVTEAEKAFMVARGIVREAHTSLEALQVRLKEVRDRLDRVSREEAHYLELATLEHKLLQEERRLRTSHENAEEAEREKFALFSAAVRESHDKERTRAERTKNWSIIGSVLGAIIGVMGSTYINRVRLQELKSLLLEAQKGPVSLQEAIKVQASLHKTQQDELSNLIHSLRTTLKGSGEDAKIGKPAIVQPAAAVVQSSTSGASEEAIQEILQNSQKAQGLIESLKPQLEQVWESLSKVGTELQTVKTTLQSRPLEKPVIQTRGTQLFVCDTETVVQGLGQTEKRLEAQINKTSLYNTVLTCAAFAVTVPVLYVLLRGT", "length": 421 }, "evidence": [ { "id": "A0A8V0ZJG3", "url": "https://omabrowser.org/oma/group/A0A8V0ZJG3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3URS9-1", "protein_name": "Mitochondrial potassium channel", "gene_name": "Ccdc51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGCSPVFAMQHVVGVPRILVRRTFLGTDVTMTRTLCSPGPREKRPEAAALGLFHRLPELGRTLSHTVRHQAASTAKAWWDRYEEFVGLNEVREAQGNVTEAEKVFMVARGLVREAREGLEAQQTKLKEVRDRLDRVSREDNQYLELATLEHRMLQEEKRLRIAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPASLQEAIREQASSYSLQQKDLQDLMMDLRGLVHAEQGQGSGSPTGSSTRGKDIDGLSATMKEQLRHSRQVYSCLEGLREQLDGLEKTCSQMAGVLQLAQAPAHPGTVGPVDGALPSSLLEHGSVILALSEMEQRLEAQANRNTVSSTLVTCVTFLATLPLLYMLFKTS", "length": 406 }, "evidence": [ { "id": "A0A8V0ZJG3", "url": "https://omabrowser.org/oma/group/A0A8V0ZJG3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5E9Q3-1", "protein_name": "Mitochondrial potassium channel", "gene_name": "CCDC51", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGRSRVLAMRHVGGVSPVLVRRDLFLTRTLCSHGPSQPREKRPEEVALGLYHRLTALGAALGHSIRQRASSTAKTWWDRYEEFVGLNEVREAQGNVTEAEKVFMVARGLVREAREDLESQQTKLKEVRDRLDRISRDDNQYLELATLEHRMLQEEKRLRMTYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSLQQRDLRDLVADLKGLVQAGTGQGSLSQAGSSPTQDRDTDVLSAALREQLSHSRQVRSRLEGLREQLDGLEKTVSQVAGVVQLAKAAAHPGLESADGALPGSLLEQGSMIMALSDTEQRLEAQVNRNTVYGTLVTCATFVAVLPVLYMLFRAS", "length": 404 }, "evidence": [ { "id": "A0A8V0ZJG3", "url": "https://omabrowser.org/oma/group/A0A8V0ZJG3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5PPN7-1", "protein_name": "Mitochondrial potassium channel", "gene_name": "Ccdc51", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGCSPVFTMQQVVGVSHRLVWRTFRGTDLLMTRTLCSPGPSRPGEKRPEAAALGLYHRLPELGRTLSHTIRNQAASTAKAWWDRYEEFVGLNEVREAQGNVTEAEKVFMVARGLVREAREDLEAQQTKLKEVRDRLDRVSREDNQYLELATLEHRMLQEEKRLRIAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSLQQKDLQNLMVDLRGLVHVGQDQGSGSPTGPSSPRGKDIDGLSAAMKEQLNHSRQVYSCLEGLREQLDSLEKTCSQMAGVVRLAKVPAHPGMVEPLDGALPSSLLEHGSTMLALSEMEQRLEAQANRNAISSTLVTCVTFMATLPLLYMLFKTS", "length": 410 }, "evidence": [ { "id": "A0A8V0ZJG3", "url": "https://omabrowser.org/oma/group/A0A8V0ZJG3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96ER9-1", "protein_name": "Mitochondrial potassium channel", "gene_name": "CCDC51", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMGRSPGFAMQHIVGVPHVLVRRGLLGRDLFMTRTLCSPGPSQPGEKRPEEVALGLHHRLPALGRALGHSIQQRATSTAKTWWDRYEEFVGLNEVREAQGKVTEAEKVFMVARGLVREAREDLEVHQAKLKEVRDRLDRVSREDSQYLELATLEHRMLQEEKRLRTAYLRAEDSEREKFSLFSAAVRESHEKERTRAERTKNWSLIGSVLGALIGVAGSTYVNRVRLQELKALLLEAQKGPVSLQEAIREQASSYSRQQRDLHNLMVDLRGLVHAAGPGQDSGSQAGSPPTRDRDVDVLSAALKEQLSHSRQVHSCLEGLREQLDGLEKTCSQMAGVVQLVKSAAHPGLVEPADGAMPSFLLEQGSMILALSDTEQRLEAQVNRNTIYSTLVTCVTFVATLPVLYMLFKAS", "length": 411 }, "evidence": [ { "id": "A0A8V0ZJG3", "url": "https://omabrowser.org/oma/group/A0A8V0ZJG3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 204, "end_pos": 206 }, { "start_pos": 312, "end_pos": 314 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJH0-1", "uniprot_ac": "A0A8V0ZJH0", "uniprot_id": "A0A8V0ZJH0_CHICK", "mass": { "chemical_mass": 20549.0, "monoisotopic_mass": 20549.0 }, "refseq": {}, "gene_names": [ { "name": "MFAP5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0" } ] } ], "protein_names": [ { "name": "Microfibril associated protein 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MFAP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0", "locus": { "chromosome": "1", "start_pos": 75931108, "end_pos": 75955329, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022764", "url": "https://www.ensembl.org/id/ENSGALG00010022764" } ] } } ], "crossref": [ { "id": "A0A8V0ZJH0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJH0", "url": "https://www.orthodb.org/?gene=A0A8V0ZJH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJJ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZJJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRQ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZRQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRR7", "url": "https://www.orthodb.org/?gene=A0A8V0ZRR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSK3", "url": "https://www.orthodb.org/?gene=A0A8V0ZSK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSK8", "url": "https://www.orthodb.org/?gene=A0A8V0ZSK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZX90", "url": "https://www.orthodb.org/?gene=A0A8V0ZX90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16485", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16485", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16485:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16485:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05507", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05507", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1566948", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1566948", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2129379", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2129379", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZJH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVQLLLSFLISFQQQGMKTSATFMALYLLAFSLSPAGWFPWVVNGQELESVTGDVHTSLLISTPAAAVTPPVLLSPVQSDTETTTASSDCREEQFPCTRLYSVHKPVKQCISYLCVTSVRRMYVINKEVCSRIVCKENEVMQDEICRQLAGLPSRRLRRSGQLSHLPCKQILEQQRRRPDAL", "length": 183, "header": "tr|A0A8V0ZJH0-1|A0A8V0ZJH0_CHICK Isoform 1 of Microfibril associated protein 5 OS=Gallus gallus OX=9031 GN=MFAP5 PE=1 SV=1 CANONICAL=A0A8V0ZJH0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0/entry#A0A8V0ZJH0-1", "sequence": { "sequence": "MAVQLLLSFLISFQQQGMKTSATFMALYLLAFSLSPAGWFPWVVNGQELESVTGDVHTSLLISTPAAAVTPPVLLSPVQSDTETTTASSDCREEQFPCTRLYSVHKPVKQCISYLCVTSVRRMYVINKEVCSRIVCKENEVMQDEICRQLAGLPSRRLRRSGQLSHLPCKQILEQQRRRPDAL", "length": 183, "header": "tr|A0A8V0ZJH0-1|A0A8V0ZJH0_CHICK Isoform 1 of Microfibril associated protein 5 OS=Gallus gallus OX=9031 GN=MFAP5 PE=1 SV=1 CANONICAL=A0A8V0ZJH0-1" }, "locus": { "chromosome": "1", "start_pos": 75952036, "end_pos": 75935215, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055337.1", "url": "https://www.ensembl.org/id/ENSGALT00010055337.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033499.1", "url": "https://www.ensembl.org/id/ENSGALP00010033499.1" } ] } }, { "isoform_ac": "A0A8V0ZJJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0/entry#A0A8V0ZJJ2-1", "sequence": { "sequence": "MHRTAGMKTSATFMALYLLAFSLSPAGWFPWVVNGQELESVTGDVHTSLLISTPAAAVTPPVLLSPVQSDTETTTASSDCREEQFPCTRLYSVHKPVKQCISYLCVTSVRRMYVINKEVCSRIVCKENEVMQDEICRQLAGLPSRRLRRSGQLSHLPCKQILEQQRRRPDAL", "length": 172, "header": "tr|A0A8V0ZJJ2-1|A0A8V0ZJJ2_CHICK Computationally mapped isoform of Microfibril associated protein 5 OS=Gallus gallus OX=9031 GN=MFAP5 PE=1 SV=1 CANONICAL=A0A8V0ZJH0-1" }, "locus": { "chromosome": "1", "start_pos": 75955202, "end_pos": 75935215, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055362.1", "url": "https://www.ensembl.org/id/ENSGALT00010055362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033519.1", "url": "https://www.ensembl.org/id/ENSGALP00010033519.1" } ] } }, { "isoform_ac": "A0A8V0ZRQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0/entry#A0A8V0ZRQ7-1", "sequence": { "sequence": "MLTWQRRLRVGTGMKTSATFMALYLLAFSLSPAGWFPWVVNGQELESVTVQSDTETTTASSDCREEQFPCTRLYSVHKPVKQCISYLCVTSVRRMYVINKEVCSRIVCKENEVMQDEICRQLAGLPSRRLRRSGQLSHLPCKQILEQQRRRPDAL", "length": 155, "header": "tr|A0A8V0ZRQ7-1|A0A8V0ZRQ7_CHICK Computationally mapped isoform of Microfibril associated protein 5 OS=Gallus gallus OX=9031 GN=MFAP5 PE=1 SV=1 CANONICAL=A0A8V0ZJH0-1" }, "locus": { "chromosome": "1", "start_pos": 75954913, "end_pos": 75935215, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055356.1", "url": "https://www.ensembl.org/id/ENSGALT00010055356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033513.1", "url": "https://www.ensembl.org/id/ENSGALP00010033513.1" } ] } }, { "isoform_ac": "A0A8V0ZRR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0/entry#A0A8V0ZRR7-1", "sequence": { "sequence": "MKTSATFMALYLLAFSLSPAGWFPWVVNGQELESVTGDVHTSLLISTPAAAVTPPVLLSPVSVQSDTETTTASSDCREEQFPCTRLYSVHKPVKQCISYLCVTSVRRMYVINKEVCSRIVCKENEVMQDEICRQLAGLPSRRLRRSGQLSHLPCKQILEQQRRRPDAL", "length": 168, "header": "tr|A0A8V0ZRR7-1|A0A8V0ZRR7_CHICK Computationally mapped isoform of Microfibril associated protein 5 OS=Gallus gallus OX=9031 GN=MFAP5 PE=1 SV=1 CANONICAL=A0A8V0ZJH0-1" }, "locus": { "chromosome": "1", "start_pos": 75945425, "end_pos": 75935215, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055366.1", "url": "https://www.ensembl.org/id/ENSGALT00010055366.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033523.1", "url": "https://www.ensembl.org/id/ENSGALP00010033523.1" } ] } }, { "isoform_ac": "A0A8V0ZSK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0/entry#A0A8V0ZSK3-1", "sequence": { "sequence": "MKTSATFMALYLLAFSLSPAGWFPWVVNGQELESVTAAAVTPPVLLSPVQSDTETTTASSDCREEQFPCTRLYSVHKPVKQCISYLCVTSVRRMYVINKEVCSRIVCKENEVMQDEICRQLAGLPSRRLRRSGQLSHLPCKQILEQQRRRPDAL", "length": 154, "header": "tr|A0A8V0ZSK3-1|A0A8V0ZJH0_CHICK Computationally mapped isoform of Microfibril associated protein 5 OS=Gallus gallus OX=9031 GN=MFAP5 PE=1 SV=1 CANONICAL=A0A8V0ZJH0-1" }, "locus": { "chromosome": "1", "start_pos": 75945425, "end_pos": 75935215, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055342.1", "url": "https://www.ensembl.org/id/ENSGALT00010055342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033502.1", "url": "https://www.ensembl.org/id/ENSGALP00010033502.1" } ] } }, { "isoform_ac": "A0A8V0ZSK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0/entry#A0A8V0ZSK8-1", "sequence": { "sequence": "MGMKTSATFMALYLLAFSLSPAGWFPWVVNGQELESVTGDVHTSLLISTPVQSDTETTTASSDCREEQFPCTRLYSVHKPVKQCISYLCVTSVRRMYVINKEVCSRIVCKENEVMQDEICRQLAGLPSRRLRRSGQLSHLPCKQILEQQRRRPDAL", "length": 156, "header": "tr|A0A8V0ZSK8-1|A0A8V0ZJH0_CHICK Computationally mapped isoform of Microfibril associated protein 5 OS=Gallus gallus OX=9031 GN=MFAP5 PE=1 SV=1 CANONICAL=A0A8V0ZJH0-1" }, "locus": { "chromosome": "1", "start_pos": 75954565, "end_pos": 75935215, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055348.1", "url": "https://www.ensembl.org/id/ENSGALT00010055348.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033507.1", "url": "https://www.ensembl.org/id/ENSGALP00010033507.1" } ] } }, { "isoform_ac": "A0A8V0ZX90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0/entry#A0A8V0ZX90-1", "sequence": { "sequence": "MKTSATFMALYLLAFSLSPAGWFPWVVNGQELESDVHTSLLISTPVQSDTETTTASSDCREEQFPCTRLYSVHKPVKQCISYLCVTSVRRMYVINKEVCSRIVCKENEVMQDEICRQLAGLPSRRLRRSGQLSHLPCKQILEQQRRRPDAL", "length": 151, "header": "tr|A0A8V0ZX90-1|A0A8V0ZJH0_CHICK Computationally mapped isoform of Microfibril associated protein 5 OS=Gallus gallus OX=9031 GN=MFAP5 PE=1 SV=1 CANONICAL=A0A8V0ZJH0-1" }, "locus": { "chromosome": "1", "start_pos": 75945425, "end_pos": 75935215, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055332.1", "url": "https://www.ensembl.org/id/ENSGALT00010055332.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033495.1", "url": "https://www.ensembl.org/id/ENSGALP00010033495.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 70, "start_aa": "Thr", "end_pos": 70, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr70", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-1566948", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1566948", "resource": "Reactome", "description": "Elastic fibre formation" }, { "id": "R-GGA-2129379", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2129379", "resource": "Reactome", "description": "Molecules associated with elastic fibres" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "embryonic eye morphogenesis", "id": "GO:0048048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048048", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0" } ], "pmid": "" }, { "name": "definitive hemopoiesis", "id": "GO:0060216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microfibril", "id": "GO:0001527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001527", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 70 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLB5-1", "uniprot_ac": "A0A8V0ZLB5", "uniprot_id": "A0A8V0ZLB5_CHICK", "mass": { "chemical_mass": 32523.0, "monoisotopic_mass": 32523.0 }, "refseq": { "ac": "XP_015152623", "name": "RING finger protein 223", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152623" }, "gene_names": [ { "name": "RNF223", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5" } ] }, { "name": "RNF223", "type": "synonym", "evidence": [ { "id": "XP_015152623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152623" } ] } ], "protein_names": [ { "name": "RING finger protein 223", "type": "synonym", "evidence": [ { "id": "XP_015152623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152623" } ] }, { "name": "Ring finger protein 223", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152623" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF223", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5", "locus": { "chromosome": "21", "start_pos": 2686333, "end_pos": 2655301, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021660", "url": "https://www.ensembl.org/id/ENSGALG00010021660" } ] } } ], "crossref": [ { "id": "A0A8V0ZLB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16556", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16556", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419428", "url": "https://www.ncbi.nlm.nih.gov/gene/419428", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419428", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419428", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YLPPKHT", "url": "https://omabrowser.org/oma/group/YLPPKHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJI3", "url": "https://www.orthodb.org/?gene=A0A8V0ZJI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLB5", "url": "https://www.orthodb.org/?gene=A0A8V0ZLB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22791", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22791", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22791:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22791:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14634", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14634", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015152623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152623", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESSALLPAQISGSTTQESPRALFLSSGSVMSCFTQLWHSSTPDSPTSPVPASPHEIPIPISPIVITSPVDSKRKARSPTDKPGSPNPTSPKPASPVECSICFNTYDNTFKTPKLLQCSHVFCLECVARLSKGLPPNHPEDQLPCPFCRQLTSIPQEGAPALETSKELLATLPPELQQEKVLWMEGTKLCCRQASDDPENPDSCISIDVAMSKPESPEVPPTGLVGRLSRCDMCDDWKRIVLLSALIIILFCIILWPVQCALKTGNLRCFTRTVAVSRPEYLPPKHTTASTPVTQLPLL", "length": 299, "header": "tr|A0A8V0ZLB5-1|A0A8V0ZLB5_CHICK Isoform 1 of Ring finger protein 223 OS=Gallus gallus OX=9031 GN=RNF223 PE=4 SV=1 CANONICAL=A0A8V0ZLB5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5/entry#A0A8V0ZJI3-1", "sequence": { "sequence": "MSCFTQLWHSSTPDSPTSPVPASPHEIPIPISPIVITSPVDSKRKARSPTDKPGSPNPTSPKPASPVECSICFNTYDNTFKTPKLLQCSHVFCLECVARLSKGLPPNHPEDQLPCPFCRQLTSIPQEGAPALETSKELLATLPPELQQEKVLWMEGTKLCCRQASDDPENPDSCISIDVAMSKPESPEVPPTGLVGRLSRCDMCDDWKRIVLLSALIIILFCIILWPVQCALKTGNLRCFTRTVAVSRPEYLPPKHTTASTPVTQLPLL", "length": 269, "header": "tr|A0A8V0ZJI3-1|A0A8V0ZLB5_CHICK Computationally mapped isoform of Ring finger protein 223 OS=Gallus gallus OX=9031 GN=RNF223 PE=4 SV=1 CANONICAL=A0A8V0ZLB5-1" }, "locus": { "chromosome": "21", "start_pos": 2670830, "end_pos": 2670024, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052617.1", "url": "https://www.ensembl.org/id/ENSGALT00010052617.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031523.1", "url": "https://www.ensembl.org/id/ENSGALP00010031523.1" } ] } }, { "isoform_ac": "A0A8V0ZLB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5/entry#A0A8V0ZLB5-1", "sequence": { "sequence": "MESSALLPAQISGSTTQESPRALFLSSGSVMSCFTQLWHSSTPDSPTSPVPASPHEIPIPISPIVITSPVDSKRKARSPTDKPGSPNPTSPKPASPVECSICFNTYDNTFKTPKLLQCSHVFCLECVARLSKGLPPNHPEDQLPCPFCRQLTSIPQEGAPALETSKELLATLPPELQQEKVLWMEGTKLCCRQASDDPENPDSCISIDVAMSKPESPEVPPTGLVGRLSRCDMCDDWKRIVLLSALIIILFCIILWPVQCALKTGNLRCFTRTVAVSRPEYLPPKHTTASTPVTQLPLL", "length": 299, "header": "tr|A0A8V0ZLB5-1|A0A8V0ZLB5_CHICK Isoform 1 of Ring finger protein 223 OS=Gallus gallus OX=9031 GN=RNF223 PE=4 SV=1 CANONICAL=A0A8V0ZLB5-1" }, "locus": { "chromosome": "21", "start_pos": 2670830, "end_pos": 2669603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052613.1", "url": "https://www.ensembl.org/id/ENSGALT00010052613.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031519.1", "url": "https://www.ensembl.org/id/ENSGALP00010031519.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419428", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419428", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9U0A4-1", "protein_name": "Ring finger protein 223", "gene_name": "RNF223", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSGPQVWHTTMPLTSRSSPTATVPRSPSSASSPRSPGTPGSEKVASPLECSICFSGYDNIFKTPKELSCTHVFCLECLARLAAAQPTGQPGSEAVPCPFCRQPTAVPAAGAPALRTSRQLQARMPAHLQQEEPVWLEGTKLCYYPSPSVPGPVEPGFMCVDIGPSKPPEPAVPVPTPDPAHRRGPLARCWARCRDWRRVALITALLLVLFCVVLWPVQCALKTGSLRCLPRPPSTAATTSSLGSLAYN", "length": 249 }, "evidence": [ { "id": "A0A8V0ZLB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZLB5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLB5" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 99, "end_pos": 149, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJK2-1", "uniprot_ac": "A0A8V0ZJK2", "uniprot_id": "A0A8V0ZJK2_CHICK", "mass": { "chemical_mass": 56722.0, "monoisotopic_mass": 56722.0 }, "refseq": { "ac": "XP_430256", "name": "zona pellucida-binding protein 2-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_430256" }, "gene_names": [ { "name": "LOC425470", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2" } ] }, { "name": "LOC425470", "type": "synonym", "evidence": [ { "id": "XP_430256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_430256" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2/entry#names_and_taxonomy" } ] }, { "name": "zona pellucida-binding protein 2-like", "type": "synonym", "evidence": [ { "id": "XP_430256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_430256" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_430256.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_430256", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_430256" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC425470", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZJK2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJK2", "database": "AlphaFoldDB", "categories": [] }, { "id": "425470", "url": "https://www.ncbi.nlm.nih.gov/gene/425470", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425470", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425470", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPPPVNE", "url": "https://omabrowser.org/oma/group/FPPPVNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJK2", "url": "https://www.orthodb.org/?gene=A0A8V0ZJK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRT0", "url": "https://www.orthodb.org/?gene=A0A8V0ZRT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15443", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15443", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15443:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15443:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_430256", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_430256", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTGCPRTAQPGRMLCAPCFCPGLGAPGLLGTMGILTLVLWSCSGQPAFLPEDLPAHSSWEYQGGDVFIHMDSSLYSLPCSTIELEVANPTYQWVRDRPDPKLLSVTEEGHLLFQNFQAADSGNYSCTISYTEHGLPVSQTFHYRVLGYHVLGGLETLMIFHSKLCKDEWTKMFLWDLLERLKQLEVEQHCKIHPETSTCFPSADNPSNEFVVQIQLTVSFFGPNWDEQCKPQGVEVDADCYRRTAQQSLKKVQHAITKFFKQHVIFHIAGPDTSRIAFITVFIGFLEIKNCSEGYGQTKQLQRCLECCVVCPPGTFSPSTNTQCSLCPMGTYTMIYGAAFCTPCKDGMITQGLGARSMTDCMKEERTKQVDAIIRKVPILLLIVLPLVIAANLLFVFASCYWYQRQYRLSSPMTSKMAGITKTMEKVTKFCRIPRQSPQARPFATALNMTSETDTSQEGEEEYLHGELTPPRTPSLAAVSDDTPAVLELEDKMSIFEVPSTNAGQKH", "length": 508, "header": "tr|A0A8V0ZJK2-1|A0A8V0ZJK2_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC425470 PE=4 SV=1 CANONICAL=A0A8V0ZJK2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2/entry#A0A8V0ZJK2-1", "sequence": { "sequence": "MVTGCPRTAQPGRMLCAPCFCPGLGAPGLLGTMGILTLVLWSCSGQPAFLPEDLPAHSSWEYQGGDVFIHMDSSLYSLPCSTIELEVANPTYQWVRDRPDPKLLSVTEEGHLLFQNFQAADSGNYSCTISYTEHGLPVSQTFHYRVLGYHVLGGLETLMIFHSKLCKDEWTKMFLWDLLERLKQLEVEQHCKIHPETSTCFPSADNPSNEFVVQIQLTVSFFGPNWDEQCKPQGVEVDADCYRRTAQQSLKKVQHAITKFFKQHVIFHIAGPDTSRIAFITVFIGFLEIKNCSEGYGQTKQLQRCLECCVVCPPGTFSPSTNTQCSLCPMGTYTMIYGAAFCTPCKDGMITQGLGARSMTDCMKEERTKQVDAIIRKVPILLLIVLPLVIAANLLFVFASCYWYQRQYRLSSPMTSKMAGITKTMEKVTKFCRIPRQSPQARPFATALNMTSETDTSQEGEEEYLHGELTPPRTPSLAAVSDDTPAVLELEDKMSIFEVPSTNAGQKH", "length": 508, "header": "tr|A0A8V0ZJK2-1|A0A8V0ZJK2_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC425470 PE=4 SV=1 CANONICAL=A0A8V0ZJK2-1" }, "locus": { "chromosome": "27", "start_pos": 1931513, "end_pos": 1927540, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055373.1", "url": "https://www.ensembl.org/id/ENSGALT00010055373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033529.1", "url": "https://www.ensembl.org/id/ENSGALP00010033529.1" } ] } }, { "isoform_ac": "A0A8V0ZRT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2/entry#A0A8V0ZRT0-1", "sequence": { "sequence": "MVTGCPRTAQPGRMLCAPCFCPGLGAPGLLGTMGILTLVLWSCSGDVFIHMDSSLYSLPCSTIELEVANPTYQWVRDRPDPKLLSVTEEGHLLFQNFQAADSGNYSCTISYTEHGLPVSQTFHYRVLGYHVLGGLETLMIFHSKLCKDEWTKMFLWDLLERLKQLEVEQHCKIHPETSTCFPSADNPSNEFVVQIQLTVSFFGPNWDEQCKPQGVEVDADCYRRTAQQSLKKVQHAITKFFKQHVIFHIAGPDTSRIAFITVFIGFLEIKNCSEGYGQTKQLQRCLECCVVCPPGTFSPSTNTQCSLCPMGTYTMIYGAAFCTPCKDGMITQGLGARSMTDCMKEERTKQVDAIIRKVPILLLIVLPLVIAANLLFVFASCYWYQRQYRLSSPMTSKMAGITKTMEKVTKFCRIPRQSPQARPFATALNMTSETDTSQEGEEEYLHGELTPPRTPSLAAVSDDTPAVLELEDKMSIFEVPSTNAGQKH", "length": 488, "header": "tr|A0A8V0ZRT0-1|A0A8V0ZRT0_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC425470 PE=4 SV=1 CANONICAL=A0A8V0ZJK2-1" }, "locus": { "chromosome": "27", "start_pos": 1931513, "end_pos": 1927540, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055379.1", "url": "https://www.ensembl.org/id/ENSGALT00010055379.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033533.1", "url": "https://www.ensembl.org/id/ENSGALP00010033533.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425470", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425470", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2" } ], "pmid": "" }, { "name": "zona pellucida receptor complex", "id": "GO:0002199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002199", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "binding of sperm to zona pellucida", "id": "GO:0007339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007339", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2" } ], "pmid": "" }, { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJK2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 47, "end_pos": 143, "start_aa": "Pro", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 449, "end_pos": 451 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJL5-1", "uniprot_ac": "A0A8V0ZJL5", "uniprot_id": "A0A8V0ZJL5_CHICK", "mass": { "chemical_mass": 25403.0, "monoisotopic_mass": 25403.0 }, "refseq": {}, "gene_names": [ { "name": "TP53INP2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5" } ] } ], "protein_names": [ { "name": "Tumor protein p53 inducible nuclear protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TP53INP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5", "locus": { "chromosome": "20", "start_pos": 880681, "end_pos": 885998, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021676", "url": "https://www.ensembl.org/id/ENSGALG00010021676" } ] } } ], "crossref": [ { "id": "A0A8V0ZJL5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJL5", "url": "https://www.orthodb.org/?gene=A0A8V0ZJL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31671:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31671:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14839", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14839", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFQRLTSLFFSDSSAPEGLEEPKPFVSEEEEEDGWLIIELGGCLGSTGSCLPLISPAPSPSSAVHPVHTDCTEPTPSRAWPWWLRGSELSWLGGGSWQAEVKEEPGPDGVGSSPMEDLLIEHPSMSVYVTSTLELDAEGPQDDAVGEVPEPRLERHVPHRSASLSVKAAVLEKVSQARRVQRAKQLAEKPWLSQKALQRQDRARQRPPRRARQRAGSFLHQPCQRHCNY", "length": 229, "header": "tr|A0A8V0ZJL5-1|A0A8V0ZJL5_CHICK Isoform 1 of Tumor protein p53 inducible nuclear protein 2 OS=Gallus gallus OX=9031 GN=TP53INP2 PE=4 SV=1 CANONICAL=A0A8V0ZJL5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5/entry#A0A8V0ZJL5-1", "sequence": { "sequence": "MFQRLTSLFFSDSSAPEGLEEPKPFVSEEEEEDGWLIIELGGCLGSTGSCLPLISPAPSPSSAVHPVHTDCTEPTPSRAWPWWLRGSELSWLGGGSWQAEVKEEPGPDGVGSSPMEDLLIEHPSMSVYVTSTLELDAEGPQDDAVGEVPEPRLERHVPHRSASLSVKAAVLEKVSQARRVQRAKQLAEKPWLSQKALQRQDRARQRPPRRARQRAGSFLHQPCQRHCNY", "length": 229, "header": "tr|A0A8V0ZJL5-1|A0A8V0ZJL5_CHICK Isoform 1 of Tumor protein p53 inducible nuclear protein 2 OS=Gallus gallus OX=9031 GN=TP53INP2 PE=4 SV=1 CANONICAL=A0A8V0ZJL5-1" }, "locus": { "chromosome": "20", "start_pos": 885795, "end_pos": 881053, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052653.1", "url": "https://www.ensembl.org/id/ENSGALT00010052653.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031559.1", "url": "https://www.ensembl.org/id/ENSGALP00010031559.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 75, "start_aa": "Thr", "end_pos": 75, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr75", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 75 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJM3-1", "uniprot_ac": "A0A8V0ZJM3", "uniprot_id": "A0A8V0ZJM3_CHICK", "mass": { "chemical_mass": 75615.0, "monoisotopic_mass": 75615.0 }, "refseq": { "ac": "XP_426381", "name": "SITS-binding protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426381" }, "gene_names": [ { "name": "LOC428824", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM3" } ] }, { "name": "LOC428824", "type": "synonym", "evidence": [ { "id": "XP_426381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426381" } ] } ], "protein_names": [ { "name": "Glycosyl hydrolase family 31 C-terminal domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM3/entry#names_and_taxonomy" } ] }, { "name": "SITS-binding protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_426381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426381" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_426381.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426381" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC428824", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZJM3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "428824", "url": "https://www.ncbi.nlm.nih.gov/gene/428824", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QWQDSQN", "url": "https://omabrowser.org/oma/group/QWQDSQN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJM3", "url": "https://www.orthodb.org/?gene=A0A8V0ZJM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXF1", "url": "https://www.orthodb.org/?gene=A0A8V0ZXF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43053", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43053", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43053:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43053:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_426381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426381", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPIARPTGRIHEAAWTSGIRELTEPWKGALGCLGVAVFFAMTIGIISWQALEQPPEEWMLRGQASGMLWDRRRGALLLRVLPMGRPLVSITVGSVPASEPPPPRNRCWQDGMEFCYSWEEEAELRISLQPTPAPGTECYSVRWTPLRPDVMLKDCFSMANVSWYGGASLCAQRWPLNSAESPEQPFVSGDFSKNPTGYGPVLERYFLGSTGVTVTVAPDVPLVLSLESHWHFCLGGAGGPLHYVLCISPDITTAHRHVGTQLAGPARALPDTTLLWSPIWQYDGPVGSAAKIKRGLRSLARRLKRHRMQEGVLALGEHGTAALATMDHVPAERRKRHGAPHAWDPAMIFPLRLSITLSPYTSIAAPLFLHLLRDGETGYWLSLQPRYGGCSIPLLTTWKGQLCARLNITNEAALSWYLSRARGLRHKLGATYVIFEGAEGNAFLEQAMSPPAELAGDQYAEMLAAALVTLGNATVISVGARSSHLPLFVQMSPLHSDWSHAGLKGLIPSALHYSLLGYNFFIPDTVGGSLAGDTPGDPELYVRWLQIVTFLPVMVFGTPPWLCCDSWVLNLTRQCIQRHRDFVVPLIIKYSKEWLSTGYPIFRPAWWLSPTDPAAFTVEDEFLIGDEVLVAPITEKGQTWRDIYLPGEGCRWRDTNSARVFDGGTVLRNYSVSLEEVPVFVKTS", "length": 684, "header": "tr|A0A8V0ZJM3-1|A0A8V0ZJM3_CHICK Isoform 1 of Glycosyl hydrolase family 31 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC428824 PE=4 SV=1 CANONICAL=A0A8V0ZJM3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM3/entry#A0A8V0ZJM3-1", "sequence": { "sequence": "MPIARPTGRIHEAAWTSGIRELTEPWKGALGCLGVAVFFAMTIGIISWQALEQPPEEWMLRGQASGMLWDRRRGALLLRVLPMGRPLVSITVGSVPASEPPPPRNRCWQDGMEFCYSWEEEAELRISLQPTPAPGTECYSVRWTPLRPDVMLKDCFSMANVSWYGGASLCAQRWPLNSAESPEQPFVSGDFSKNPTGYGPVLERYFLGSTGVTVTVAPDVPLVLSLESHWHFCLGGAGGPLHYVLCISPDITTAHRHVGTQLAGPARALPDTTLLWSPIWQYDGPVGSAAKIKRGLRSLARRLKRHRMQEGVLALGEHGTAALATMDHVPAERRKRHGAPHAWDPAMIFPLRLSITLSPYTSIAAPLFLHLLRDGETGYWLSLQPRYGGCSIPLLTTWKGQLCARLNITNEAALSWYLSRARGLRHKLGATYVIFEGAEGNAFLEQAMSPPAELAGDQYAEMLAAALVTLGNATVISVGARSSHLPLFVQMSPLHSDWSHAGLKGLIPSALHYSLLGYNFFIPDTVGGSLAGDTPGDPELYVRWLQIVTFLPVMVFGTPPWLCCDSWVLNLTRQCIQRHRDFVVPLIIKYSKEWLSTGYPIFRPAWWLSPTDPAAFTVEDEFLIGDEVLVAPITEKGQTWRDIYLPGEGCRWRDTNSARVFDGGTVLRNYSVSLEEVPVFVKTS", "length": 684, "header": "tr|A0A8V0ZJM3-1|A0A8V0ZJM3_CHICK Isoform 1 of Glycosyl hydrolase family 31 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC428824 PE=4 SV=1 CANONICAL=A0A8V0ZJM3-1" }, "locus": { "chromosome": "5", "start_pos": 1595359, "end_pos": 1582772, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055405.1", "url": "https://www.ensembl.org/id/ENSGALT00010055405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033549.1", "url": "https://www.ensembl.org/id/ENSGALP00010033549.1" } ] } }, { "isoform_ac": "A0A8V0ZXF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM3/entry#A0A8V0ZXF1-1", "sequence": { "sequence": "MPIARPTGRIHEAAWTSGIRELTEPWKGALGCLGVAVFFAMTIGIISWQALEQPPEEWMLRGQASGMLWDRRRGALLLRVLPMGRPLVSITVGSVPASEPPPPRNRCWQDGMEFCYSWEEEAELRISLQPTPAPGTECYSVRWTPLRPDVMLKDCFSMANVSWYGGASLCAQRWPLNSAESPEQPFVSGDFSKNPTGYGPVLERYFLGSTVTVTVAPDVPLVLSLESHWHFCLGGAGGPLHYVLCISPDITTAHRHVGTQLAGPARALPDTTLLWSPIWQYDGPVGSAAKIKRGLRSLARRLKRHRMQEGVLALGEHGTAALATMDHVPAERRKRHGAPHAWDPAMIFPLRLSITLSPYTSIAAPLFLHLLRDGETGYWLSLQPRYGGCSIPLLTTWKGQLCARLNITNEAALSWYLSRARGLRHKLGATYVIFEGAEGNAFLEQAMSPPAELAGDQYAEMLAAALVTLGNATVISVGARSSHLPLFVQMSPLHSDWSHAGLKGLIPSALHYSLLGYNFFIPDTVGGSLAGDTPGDPELYVRWLQIVTFLPVMVFGTPPWLCCDSWVLNLTRQCIQRHRDFVVPLIIKYSKEWLSTGYPIFRPAWWLSPTDPAAFTVEDEFLIGDEVLVAPITEKGQTWRDIYLPGEGCRWRDTNSARVFDGGTVLRNYSVSLEEVPVFVKTS", "length": 683, "header": "tr|A0A8V0ZXF1-1|A0A8V0ZJM3_CHICK Computationally mapped isoform of Glycosyl hydrolase family 31 C-terminal domain-containing protein OS=Gallus gallus OX=9031 GN=LOC428824 PE=4 SV=1 CANONICAL=A0A8V0ZJM3-1" }, "locus": { "chromosome": "5", "start_pos": 1595359, "end_pos": 1582772, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055413.1", "url": "https://www.ensembl.org/id/ENSGALT00010055413.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033555.1", "url": "https://www.ensembl.org/id/ENSGALP00010033555.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 131, "start_aa": "Thr", "end_pos": 131, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr131", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJM3" }, { "id": "PF21365", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21365" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl hydrolase family 31 C-terminal", "eco_id": "ECO_0000259", "start_pos": 598, "end_pos": 682, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 131 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 472, "end_pos": 474 }, { "start_pos": 570, "end_pos": 572 }, { "start_pos": 669, "end_pos": 671 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJR4-1", "uniprot_ac": "A0A8V0ZJR4", "uniprot_id": "A0A8V0ZJR4_CHICK", "mass": { "chemical_mass": 104733.0, "monoisotopic_mass": 104733.0 }, "refseq": {}, "gene_names": [ { "name": "SNX19", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR4" } ] } ], "protein_names": [ { "name": "Sorting nexin-19", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in intracellular vesicle trafficking and exocytosis. May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR4#function" }, { "database": "UniProtKB", "id": "ARBA00053440", "url": "https://www.uniprot.org/uniprotkb/ARBA00053440#function" }, { "database": "UniProtKB", "id": "A0A8V0ZSW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZXI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXI4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNX19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR4", "locus": { "chromosome": "24", "start_pos": 1831450, "end_pos": 1850997, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022804", "url": "https://www.ensembl.org/id/ENSGALG00010022804" } ] } } ], "crossref": [ { "id": "A0A8V0ZJR4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJR4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06893", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06893", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419734", "url": "https://www.ncbi.nlm.nih.gov/gene/419734", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419734", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419734", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGQHLQS", "url": "https://omabrowser.org/oma/group/CGQHLQS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSW2", "url": "https://www.orthodb.org/?gene=A0A8V0ZSW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22775", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22775", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22775:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22775:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZJR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXI4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCHRELLALLAVLGWLLVLLLDLRALALLCGTAALLGGWLGPRALSRPGWRLRLERFAGSLRPAAASPEAEEQLEQEISSTIRKVVRDFVSSWYCTVSSECAFEAEVEKAMAGLAAELRRRMARVDRQALARRLLLLCGHHLQSYLQALRGRGPLWQEYRQIAGLHPALCSPAAEVSYARASVELLLRALVPRPHLETRTGHFVVVELVACNVLLPAVRKMADPDWINLLLVGAFPRKAQGEEPSPAAPVPDSLPLIVQPDVAPAVPLLSPSPGREAGAGGEDGADVPSEPPRSEGVVLRPRGLGLLFPYEGLELDSPGQDVELLAPSPAGEFLDEPLPDVPAPLEGADTSEDGMGDLEDGHTTSSDASLLLPSAYALGPCPDIQIDPVMETEEDSPKKPSVQRPCSLGKELGTPEAPPQSPSDPGQPLPLLSSSPTAPISTFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTIKYETALEGEVVGSLQQMAYHTVNRRYREFLNLQTRLEEKPELRKFLKNIKGPKKLFPDLPFGNMDSDKVEARKSLLESFLKQLCAVPEIANSEEVQEFLALNTDARIAFVKKPFVVSRIDKIVVNAIVDTLKTAFPRSEPQSPTEDLSESEVDGKCQPDGKKANKSRLRFPSSKITPVLSVSEAHDRIVYSVREGSAVSGTLSLAAMESFIQKQEKVLEAVPSKAPEGEGSEEAKEKSVQEDIDGLSTSEQGVHLDTDTDSETALADLALDLLRLLLMDHWTWLGMENIQKVFHLLFGTLIQRFISTWEQGCVFWMWHADLMLSPLIVQKKSFGISWWLEVQVVNLTCTQRWVQYLQLLQESIWPGGVLPEIPKPARTEEQKKAAAEQALQSLMGILPNVVQEILGTDKCRMSWSLVLESLGHPVINRHLVFCLLDVLLEFLVLKGSSDELETATVVPPDSSGLEKAGGAAH", "length": 957, "header": "tr|A0A8V0ZJR4-1|A0A8V0ZJR4_CHICK Isoform 1 of Sorting nexin-19 OS=Gallus gallus OX=9031 GN=SNX19 PE=3 SV=1 CANONICAL=A0A8V0ZJR4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR4/entry#A0A8V0ZJR1-1", "sequence": { "sequence": "MDHWTWLGMENIQKVFHLLFGTLIQRFISTWEQGCVFWMWHADLMLSPLIVQKKSFGISWWLEVQVVNLTCTQRWVQYLQLLQESIWPGGVLPEIPKPARTEEQKKAAAEQALQSLMGILPNVVQEILGTDKCRMSWSLVLESLGHPVINRHLVFCLLDVLLEFLVLKGSSDELETATVVPPDSSGLEKAGGAAH", "length": 195, "header": "tr|A0A8V0ZJR1-1|A0A8V0ZJR4_CHICK Computationally mapped isoform of Sorting nexin-19 OS=Gallus gallus OX=9031 GN=SNX19 PE=3 SV=1 CANONICAL=A0A8V0ZJR4-1" }, "locus": { "chromosome": "24", "start_pos": 1843743, "end_pos": 1832862, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055457.1", "url": "https://www.ensembl.org/id/ENSGALT00010055457.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033584.1", "url": "https://www.ensembl.org/id/ENSGALP00010033584.1" } ] } }, { "isoform_ac": "A0A8V0ZJR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR4/entry#A0A8V0ZJR4-1", "sequence": { "sequence": "MPCHRELLALLAVLGWLLVLLLDLRALALLCGTAALLGGWLGPRALSRPGWRLRLERFAGSLRPAAASPEAEEQLEQEISSTIRKVVRDFVSSWYCTVSSECAFEAEVEKAMAGLAAELRRRMARVDRQALARRLLLLCGHHLQSYLQALRGRGPLWQEYRQIAGLHPALCSPAAEVSYARASVELLLRALVPRPHLETRTGHFVVVELVACNVLLPAVRKMADPDWINLLLVGAFPRKAQGEEPSPAAPVPDSLPLIVQPDVAPAVPLLSPSPGREAGAGGEDGADVPSEPPRSEGVVLRPRGLGLLFPYEGLELDSPGQDVELLAPSPAGEFLDEPLPDVPAPLEGADTSEDGMGDLEDGHTTSSDASLLLPSAYALGPCPDIQIDPVMETEEDSPKKPSVQRPCSLGKELGTPEAPPQSPSDPGQPLPLLSSSPTAPISTFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTIKYETALEGEVVGSLQQMAYHTVNRRYREFLNLQTRLEEKPELRKFLKNIKGPKKLFPDLPFGNMDSDKVEARKSLLESFLKQLCAVPEIANSEEVQEFLALNTDARIAFVKKPFVVSRIDKIVVNAIVDTLKTAFPRSEPQSPTEDLSESEVDGKCQPDGKKANKSRLRFPSSKITPVLSVSEAHDRIVYSVREGSAVSGTLSLAAMESFIQKQEKVLEAVPSKAPEGEGSEEAKEKSVQEDIDGLSTSEQGVHLDTDTDSETALADLALDLLRLLLMDHWTWLGMENIQKVFHLLFGTLIQRFISTWEQGCVFWMWHADLMLSPLIVQKKSFGISWWLEVQVVNLTCTQRWVQYLQLLQESIWPGGVLPEIPKPARTEEQKKAAAEQALQSLMGILPNVVQEILGTDKCRMSWSLVLESLGHPVINRHLVFCLLDVLLEFLVLKGSSDELETATVVPPDSSGLEKAGGAAH", "length": 957, "header": "tr|A0A8V0ZJR4-1|A0A8V0ZJR4_CHICK Isoform 1 of Sorting nexin-19 OS=Gallus gallus OX=9031 GN=SNX19 PE=3 SV=1 CANONICAL=A0A8V0ZJR4-1" }, "locus": { "chromosome": "24", "start_pos": 1850391, "end_pos": 1832862, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055462.1", "url": "https://www.ensembl.org/id/ENSGALT00010055462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033589.1", "url": "https://www.ensembl.org/id/ENSGALP00010033589.1" } ] } }, { "isoform_ac": "A0A8V0ZSW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR4/entry#A0A8V0ZSW2-1", "sequence": { "sequence": "MPCHRELLALLAVLGWLLVLLLDLRALALLCGTAALLGGWLGPRALSRPGWRLRLERFAGSLRPAAASPEAEEQLEQEISSTIRKVVRDFVSSWYCTVSSECAFEAEVEKAMAGLAAELRRRMARVDRQALARRLLLLCGHHLQSYLQALRGRGPLWQEYRQIAGLHPALCSPAAEVSYARASVELLLRALVPRPHLETRTGHFVVVELVACNVLLPAVRKMADPDWINLLLVGAFPRKAQGEEPSPAAPVPDSLPLIVQPDVAPAVPLLSPSPGREAGAGGEDGADVPSEPPRSEGVVLRPRGLGLLFPYEGLELDSPGQDVELLAPSPAGEFLDEPLPDVPAPLEGADTSEDGMGDLEDGHTTSSDASLLLPSAYALGPCPDIQIDPVMETEEDSPKKPSVQRPCSLGKELGTPEAPPQSPSDPGQPLPLLSSSPTAPISTFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTIKYETALEGEVVGSLQQMAYHTVNRRYREFLNLQTRLEEKPELRKFLKNIKGPKKLFPDLPFGNMDSDKVEARKSLLESFLKQLCAVPEIANSEEVQEFLALNTDARIAFVKKPFVVSRIDKIVVNAIVDTLKTAFPRSEPQSPTEDLSESEVDGKCQPDGKKANKSRLRFPSSKITPVLSVSEAHDRIVYSVREGSAVSGTLSLAAMESFIQKQEKVLEAVPSKAPEGEGSEEAKEKSVQEDIDGLSTSEQGVHLDTDTDSETALADLALDLLRLLLMDHWTWLGMENIQKVFHLLFGTLIQRWLEVQVVNLTCTQRWVQYLQLLQESIWPGGVLPEIPKPARTEEQKKAAAEQALQSLMGILPNVVQEILGTDKCRMSWSLVLESLGHPVINRHLVFCLLDVLLEFLVLKGSSDELETATVVPPDSSGLEKAGGAAH", "length": 923, "header": "tr|A0A8V0ZSW2-1|A0A8V0ZJR4_CHICK Computationally mapped isoform of Sorting nexin-19 OS=Gallus gallus OX=9031 GN=SNX19 PE=3 SV=1 CANONICAL=A0A8V0ZJR4-1" }, "locus": { "chromosome": "24", "start_pos": 1850391, "end_pos": 1832862, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055465.1", "url": "https://www.ensembl.org/id/ENSGALT00010055465.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033592.1", "url": "https://www.ensembl.org/id/ENSGALP00010033592.1" } ] } }, { "isoform_ac": "A0A8V0ZXI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJR4/entry#A0A8V0ZXI4-1", "sequence": { "sequence": "MAGLAAELRRRMARVDRQALARRLLLLCGHHLQSYLQALRGRGPLWQEYRQIAGLHPALCSPAAEVSYARASVELLLRALVPRPHLETRTGHFVVVELVACNVLLPAVRKMADPDWINLLLVGAFPRKAQGEEPSPAAPVPDSLPLIVQPDVAPAVPLLSPSPGREAGAGGEDGADVPSEPPRSEGVVLRPRGLGLLFPYEGLELDSPGQDVELLAPSPAGEFLDEPLPDVPAPLEGADTSEDGMGDLEDGHTTSSDASLLLPSAYALGPCPDIQIDPVMETEEDSPKKPSVQRPCSLGKELGTPEAPPQSPSDPGQPLPLLSSSPTAPISTFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTIKYETALEGEVVGSLQQMAYHTVNRRYREFLNLQTRLEEKPELRKFLKNIKGPKKLFPDLPFGNMDSDKVEARKSLLESFLKQLCAVPEIANSEEVQEFLALNTDARIAFVKKPFVVSRIDKIVVNAIVDTLKTAFPRSEPQSPTEDLSESEVDGKCQPDGKKANKSRLRFPSSKITPVLSVSEAHDRIVYSVREGSAVSGTLSLAAMESFIQKQEKVLEAVPSKAPEGEGSEEAKEKSVQEDIDGLSTSEQGVHLDTDTDSETALADLALDLLRLLLMDHWTWLGMENIQKVFHLLFGTLIQRWLEVQVVNLTCTQRWVQYLQLLQESIWPGGVLPEIPKPARTEEQKKAAAEQALQSLMGILPNVVQEILGTDKCRMSWSLVLESLGHPVINRHLVFCLLDVLLEFLVLKGSSDELETATVVPPDSSGLEKAGGAAH", "length": 812, "header": "tr|A0A8V0ZXI4-1|A0A8V0ZJR4_CHICK Computationally mapped isoform of Sorting nexin-19 OS=Gallus gallus OX=9031 GN=SNX19 PE=3 SV=1 CANONICAL=A0A8V0ZJR4-1" }, "locus": { "chromosome": "24", "start_pos": 1850058, "end_pos": 1832862, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055458.1", "url": "https://www.ensembl.org/id/ENSGALT00010055458.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033585.1", "url": "https://www.ensembl.org/id/ENSGALP00010033585.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419734", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419734", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BNC7-1", "protein_name": "Sorting nexin-19", "gene_name": "SNX19", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAEAAALSQEPAAEPSCSLGHLFSSRKLLAVGAVLGWLLVIHLLVNVWLLCLLSALLLVLGGWLGSDAIVGASGRLHLERFIPLAICPPNPEAERQLEQEIDRTIRLIMRDFVSSWYRTVSQEPAFEEEMEAAMRGLVQELRRRMAMVDRHALAQRVLTLCGCHLQSYIQAKEATAGKQSGTVEPSQLWEAYCRTTAPHPAVQSPSTEVTYTREIVDLLLKGLVPKPHLETRTGRHVVVELITCNVILPLISKLSDPDWIHLVLVGIFSKARNNPAGTMKPLCQASTLEQPSVPTSLPLIVEVQSLPKVRAPSPAAVPVLLDCSEPDGPSHLSPEVEEGREALEGDLGVVLEERRVGNNPSHFLQPGITGPLFLSEDAELESPLSELGKETIMLMTPGNFLSDKIPNVLCVLGGSHSLEAKDAEGSEGVEEAEAEEGPGTETDSGLLVSMLNTCPEIHIDTADKEVEQGDVTSLATLLASPERTCPPRPPCLEKELTNGVSALDPSLPQVLLSSSPPGPLSAATFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALEGESSSGLQQLAYHTVNRRYREFLNLQTRLEEKSDLRKLLKNVKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFVVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAETESKPQAEGKKASKSRLRFSSSKIAPALNIAEAHEKILYCLQEGSVESEVLSMSGMESFIEKQTKLLEMQPAEAPGKDSEQISKECVDGFEAEAAVPAQDLSNNDAGAETALANTALDLLLLLLMEQWRWLCTENVQKVLHLIFGTLIQRWLEVQVANLTCPQRWVQYLRLLQESIWPGGVLPKYPRPVRTQEQKVAAEEQALQSLMGVLPDIVVEILGVNKCRLSWSLVLESLQQPLINRHLIYCLWDLILEFLDLNASVEESAMTTSASETPSNPKKMGVSP", "length": 1002 }, "evidence": [ { "id": "A0A8V0ZJR4", "url": "https://omabrowser.org/oma/group/A0A8V0ZJR4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZXB9-1", "protein_name": "Sorting nexin-19", "gene_name": "Snx19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKAQTVSPAQGNIPESSYVNSNLWSSRKLMVVGVLLGWLLVIHLLVNVWLLILLCASLVVLGGWLGSTAIVGASGQLHLERFISITTCPPCPEAERHLEQEINCTIQMIIRDFVLSWYRSVSHEKTFEAEMEASMKGLVQELRRRMSIVDSHALTQRVLTLCGCHLQSYIQAKGATAKEQSCPVEPSQLWDAYCQVTTPHPAMSCPTTEVTYARGIVNLILKELVPKPHLETRTGRHVVVELITCNVILPLISKLSDPDWIHLILVSIFSKYKQDAAQGTKPPSSPCVLEQPSVPTSLPLMVEVESLPVGKASSPVAAPVHLASSEPAPSPEIEEGHEAVEGELPGMLEERKVGNNSSHFLQPDIRGPLFLCEDSELESPLSELGKETIMLMTPGNFLSHRIQDALCALDDSQALEPRDGEGSECMEGAEAEEAPGAETETGTLVSMLNCPEIQIDPADKEAEQGDDASLTALLEEPEKPCLQRPSCLDKGLGSGACSLEPAVPPLSLSSSPPGPLSSATFSFESLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALSGENSSGLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLPFGNMDSDRVEARKSLLESFLRQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKASKSRLRFSSSKIAPALSIAEAQDKILYCLQEGNSESEVLSMSGMESFIEKQTKLLQMQPAEVPDKEPQQVPKESVDSGLLDKAVVSQELNKSDPGTETELADTAFDLILLLLMEQWKWLCTENMQKFLRLVFGTLVQRWLEVQVANLTCPQRWAQYLRLLRESIWPGGVLPKFPRPGRTQAQKAATEKQALQSLMGLLPDFLVEILGVHKCQLSWSLVLESFQQPLINRHLIYCLGDIILEFLDLSAAVEECAPTTSASDSPGSLKKMAVST", "length": 997 }, "evidence": [ { "id": "A0A8V0ZJR4", "url": "https://omabrowser.org/oma/group/A0A8V0ZJR4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BKW9-1", "protein_name": "Sorting nexin-19", "gene_name": "SNX19", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKTETEILAPERPAGPGVSHLLSSRKLVALGAVLGWLLVIHLLVNVWLLCLLSALLLVLGGWLGSDAIVGASGRLHLERFIPMAVCPPNPEAERQLEQEIDRTIRMIMRDFVSSWYRTVSQEPAFEEEMEAAMRGLVQELRRRMARVDSHALAQRVLTLCGCHLQSYIQAKEAAGKQSGPGEPSQLWEAYCRASAPHPAVQSPSAEVTYTRGIVNVLLQGLVPKPHLETRTGRHIVVELITCNVILPLISKLSDPDWIHLVLVGIFSKARTNPAGVANPLCPASALEQPSVPTSLPLIVEIQGLAEAPSPAAAPVLLSCSEPDGPSHPSPDIEEGHEALEGDLGGVLEERKVENSSSHFLQPLFLSEDAELESPLSELSKETIMLMTPGPFLSASIQDALCALGGSQPLEPKDGKGPEGIEGAEAEEGPGTETEPGLLASMLNSCPEIQIDTADKEGEQGNDACLTTLLPSPERICPPRPSCLEKDLTNGGSSLDSSLPQVLLSSSPPGPLSSATFNFESLGSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALDGESSGGLQHVAYHTVNRRYREFLNLQTRLEEKSDLRKFIKNVKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEMQEFLALNTDARIAFVKKPFVVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAETENKPQTEGKKASKSRLRFSSSKIAPALNITEAHEKVLYCLQDSGVESETLSVSGMESFIEKQAKLLEVQPADAPGRDSEQTAEGCVDGRVSDAAAPAQGLSSSDPGTETELADTALDLLVLLLMEQWRWLCTESVQKVLHLVFGTLIQRWLEVQVAHLTCPQRWVQYLRLLQESIWPGGALPKCPRPVRTPEQKAAAEKQALQSLMGVLPDVIVEILGENKCRLSWSLVLESLQQPLINRHLIYCLWDIILELLELSASAEESAVTSSTADTPGRRASPLSQRPLSRFFEG", "length": 1000 }, "evidence": [ { "id": "A0A8V0ZJR4", "url": "https://omabrowser.org/oma/group/A0A8V0ZJR4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6P4T1-1", "protein_name": "Sorting nexin-19", "gene_name": "Snx19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKAQTVSPTQGTISESSYVHSNLWSSRKLMIVGVLVGWLLVIHLLVNMWLLILLCASLVALGGWLGSTAILGASGQLHLERFITITTCPPCPEAERQLEQEINRTIQMIIRDFVLSWYRSVSHEPAFEAEMEAAMKGLVQELRRRMSIVDSHALTQRVLTLCGCHLQSYIQAKEATAKEQSCPVQPSQLWDAYCQVTAPHPAMSCPTTEVTYARGIVNLILKELVPKPHLETRTGRHVVVEVITCNVILPLISKLSDPDWIHLILVSIFSKYRHDAAQGTKPPCSSSVLEQPSVPTSLPLIVEVESLPVGKASSPATAPVHLTSSEPAPSPEIEEGHEAVEGDLPGMLEEKKVGNSSSHFLQPDIRGPLFLCEDSELESPLSELSKETILLMTPGNFLSDRIQDALCALDDSGALEPKDGEGSECMEGAEAEEAPGTDTETGMLVSVLNCPEIQIDTADKEVEQGDDTSLTALLEEPEKPCPLRPSCLDKDLASGVCSLEPAMPPVPLSSSPPGPLSSATFSFESLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETVLNGENSSGLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIGNSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKASKSRLRFSSSKIAPALSIAEAQDKILYCLQEGNSESEVLSMSGMESFIEKQTKLLRIQPAEVPDKDPQQVPKEYVDSGLLDKAVVAQELNKSGPGTETELADTAFDLILLLLMEQWKWLCTESMQKFLHIIFGTLVQRWLEVQVANLTCPQRWAQYLHLLRESIWPGGVLPKFPRPGRTQAQKAATEKQALQSLMDLLPDFLVEILGVNKCRLSWSLVLESFQQPLINRHLIYCLGDIILELLDLSASVEECAPATSASDSPGSLKKMAVST", "length": 997 }, "evidence": [ { "id": "A0A8V0ZJR4", "url": "https://omabrowser.org/oma/group/A0A8V0ZJR4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92543-1", "protein_name": "Sorting nexin-19", "gene_name": "SNX19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKTETVPPFQETPAGSSCHLNNLLSSRKLMAVGVLLGWLLVIHLLVNVWLLCLLSALLVVLGGWLGSSLAGVASGRLHLERFIPLATCPPCPEAERQLEREINRTIQMIIRDFVLSWYRSVSQEPAFEEEMEAAMKGLVQELRRRMSVMDSHAVAQSVLTLCGCHLQSYIQAKEATAGKNGPVEPSHLWEAYCRATAPHPAVHSPSAEVTYTRGVVNLLLQGLVPKPHLETRTGRHVVVELITCNVILPLISRLSDPDWIHLVLVGIFSKARDPAPCPASAPEQPSVPTSLPLIAEVEQLPEGRASPVAAPVFLSYSEPEGSAGPSPEVEEGHEAVEGDLGGMCEERKVGNNSSHFLQPNVRGPLFLCEDSELESPLSELGKETIMLMTPGSFLSDRIQDALCALESSQALEPKDGEASEGAEAEEGPGTETETGLPVSTLNSCPEIHIDTADKEIEQGDVTASVTALLEGPEKTCPSRPSCLEKDLTNDVSSLDPTLPPVLLSSSPPGPLSSATFSFEPLSSPDGPVIIQNLRITGTITAREHSGTGFHPYTLYTVKYETALDGENSSGLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLPLGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAETESKPQTEGKKASKSRLRFSSSKISPALSVTEAQDKILYCLQEGNVESETLSMSAMESFIEKQTKLLEMQPTKAPEKDPEQPPKGRVDSCVSDAAVPAQDPSNSDPGTETELADTALDLLLLLLTEQWKWLCTENMQKFLRLIFGTLVQRWLEVQVANLTSPQRWVQYLLLLQESIWPGGVLPKFPRPVRTQEQKLAAEKQALQSLMGVLPDLVVEILGVNKCRLSWGLVLESLQQPLINRHLIYCLGDIILEFLDLSASVEESAATTSASDTPGNSKRMGVSS", 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This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_004942211.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942211", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942211" } ] }, { "annotation": "May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU7#function" }, { "database": "UniProtKB", "id": "ARBA00059734", "url": "https://www.uniprot.org/uniprotkb/ARBA00059734#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC35G1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJU7", "locus": { "chromosome": "6", "start_pos": 21071235, "end_pos": 21077235, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020236", "url": 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"crossref": [ { "id": "A0A8V0ZJV6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJV6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJV6", "url": "https://www.orthodb.org/?gene=A0A8V0ZJV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12489:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12489:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10242", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10242", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPSQEASKLYHDNYVRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVNTPKPGYFGLFHYCVGSGLAGRELACRGSFTDFSTIPSGAFQAAAFFVLLSMVLTLGCITCFALFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGEKTGKYSLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQNDLLHEELKTESKGGRCATRFCRHREDIRPSTRSRTSSRGRRPGRSLPVLPLICRRWPRSAPGRTARTGAVPAARRAHVHTDTAIPRTPPAPHLRRRRGRMPQTRFV", "length": 308, "header": "tr|A0A8V0ZJV6-1|A0A8V0ZJV6_CHICK Isoform 1 of LHFPL tetraspan subfamily member 4 protein OS=Gallus gallus OX=9031 GN=LHFPL4 PE=3 SV=1 CANONICAL=A0A8V0ZJV6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6/entry#A0A8V0ZJV6-1", "sequence": { "sequence": "MLPSQEASKLYHDNYVRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVNTPKPGYFGLFHYCVGSGLAGRELACRGSFTDFSTIPSGAFQAAAFFVLLSMVLTLGCITCFALFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGEKTGKYSLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQNDLLHEELKTESKGGRCATRFCRHREDIRPSTRSRTSSRGRRPGRSLPVLPLICRRWPRSAPGRTARTGAVPAARRAHVHTDTAIPRTPPAPHLRRRRGRMPQTRFV", "length": 308, "header": "tr|A0A8V0ZJV6-1|A0A8V0ZJV6_CHICK Isoform 1 of LHFPL tetraspan subfamily member 4 protein OS=Gallus gallus OX=9031 GN=LHFPL4 PE=3 SV=1 CANONICAL=A0A8V0ZJV6-1" }, "locus": { "chromosome": "12", "start_pos": 11608578, "end_pos": 11602867, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052042.1", "url": "https://www.ensembl.org/id/ENSGALT00010052042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031067.1", "url": "https://www.ensembl.org/id/ENSGALP00010031067.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "gamma-aminobutyric acid receptor clustering", "id": "GO:0097112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097112", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6" } ], "pmid": "" }, { "name": "regulation of inhibitory synapse assembly", "id": "GO:1905702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905702", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6" } ], "pmid": "" }, { "name": "neurotransmitter receptor localization to postsynaptic specialization membrane", "id": "GO:0099645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099645", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6" } ], "pmid": "" }, { "name": "inhibitory synapse", "id": "GO:0060077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060077", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6" } ], "pmid": "" }, { "name": "postsynaptic specialization", "id": "GO:0099572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099572", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GABA receptor binding", "id": "GO:0050811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJW0-1", "uniprot_ac": "A0A8V0ZJW0", "uniprot_id": "A0A8V0ZJW0_CHICK", "mass": { "chemical_mass": 45317.0, "monoisotopic_mass": 45317.0 }, "refseq": { "ac": "XP_426398", "name": "olfactomedin-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426398" }, "gene_names": [ { "name": "OLFML1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW0" } ] }, { "name": "OLFML1", "type": "synonym", "evidence": [ { "id": "XP_426398", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426398" } ] } ], "protein_names": [ { "name": "Olfactomedin like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW0/entry#names_and_taxonomy" } ] }, { "name": "olfactomedin-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_426398", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426398" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_426398.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426398", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426398" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OLFML1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW0", "locus": { "chromosome": "5", "start_pos": 6979834, "end_pos": 6971122, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021450", "url": "https://www.ensembl.org/id/ENSGALG00010021450" } ] } } ], "crossref": [ { "id": "A0A8V0ZJW0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJW0", "database": "AlphaFoldDB", "categories": [] }, { "id": "428842", "url": "https://www.ncbi.nlm.nih.gov/gene/428842", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IHYHPGD", "url": "https://omabrowser.org/oma/group/IHYHPGD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJW0", "url": "https://www.orthodb.org/?gene=A0A8V0ZJW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_426398", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426398", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIIVGLHFLLVPFLKNIMGEAQYVMQDAALMNYIDRRILSLENRLEKCNQDILDYVEEFRDFSKMVLSRLSGLNSYKTEVKDEVENLLTRVERAQRDIDYFGSVRDSKTCVEVDEDLVKQQLLEEAEEKRKLKVILNASCDHMLAGVKSLKIVKKTGDKHGSWMKDPGKKHAKIYLLNGPVNNVIFEFANIMTFMESNHTLKARRVILPFPWEGTGHIIYQGFLFYHRHGSLNEILKFNIQKRNIVDHMLLPGAGRIPAYQLSPSTKIDLAIDEQGLWAIHAEPEIGGNIVITKINHITMSVEHTWDTTCSSKDAEAAFMACNTLYVVYNFPSGGTSRIQCAYDVLGAVNTYEIPVLHFPKRQGSHSTIHYDPKEKQLLAWGDGSQIIYKLQNQQKG", "length": 397, "header": "tr|A0A8V0ZJW0-1|A0A8V0ZJW0_CHICK Isoform 1 of Olfactomedin like 1 OS=Gallus gallus OX=9031 GN=OLFML1 PE=1 SV=1 CANONICAL=A0A8V0ZJW0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW0/entry#A0A8V0ZJW0-1", "sequence": { "sequence": "MIIVGLHFLLVPFLKNIMGEAQYVMQDAALMNYIDRRILSLENRLEKCNQDILDYVEEFRDFSKMVLSRLSGLNSYKTEVKDEVENLLTRVERAQRDIDYFGSVRDSKTCVEVDEDLVKQQLLEEAEEKRKLKVILNASCDHMLAGVKSLKIVKKTGDKHGSWMKDPGKKHAKIYLLNGPVNNVIFEFANIMTFMESNHTLKARRVILPFPWEGTGHIIYQGFLFYHRHGSLNEILKFNIQKRNIVDHMLLPGAGRIPAYQLSPSTKIDLAIDEQGLWAIHAEPEIGGNIVITKINHITMSVEHTWDTTCSSKDAEAAFMACNTLYVVYNFPSGGTSRIQCAYDVLGAVNTYEIPVLHFPKRQGSHSTIHYDPKEKQLLAWGDGSQIIYKLQNQQKG", "length": 397, "header": "tr|A0A8V0ZJW0-1|A0A8V0ZJW0_CHICK Isoform 1 of Olfactomedin like 1 OS=Gallus gallus OX=9031 GN=OLFML1 PE=1 SV=1 CANONICAL=A0A8V0ZJW0-1" }, "locus": { "chromosome": "5", "start_pos": 6978228, "end_pos": 6971420, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052002.1", "url": "https://www.ensembl.org/id/ENSGALT00010052002.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031040.1", "url": "https://www.ensembl.org/id/ENSGALP00010031040.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F1N583-1", "protein_name": "Olfactomedin like 1", "gene_name": "OLFML1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMLALRRACIFRALVFMAFLPPPQRAQDPAMVHYIYQRFQVLEQGLQKCTQATRAYIQDFQEFSKNISIMLGQCHTYTSEYKSAVHNLALRVERAQREIDYLEYLREADACVESEDKVLAEKLVQEAEEDQRIRMLLNASCDNMLMGIKSLKIVKKTTDTDGSWMKDAVSDSPKVYVFIGPRNNTVWEFANIRAFMEDSTKPAPRKLILTHSWQGTGQVIYKGFLFFHSQGTPNEIIKYNLQKRIVEDRMLLFGGAGRALAYQHSPSTYIDLAVDEHGLWAIHSGPGIRSHLVLTKIEPDTLGVEHSWDTPCRSQDAEASFLLCGVLYVVYSSGGHGPHRITCVYDPLGTIMEENLPNLFFPRRPRSHSMIHYNPRDKHLYAWNDGNQMIYKLQTRRKQPLQ", "length": 402 }, "evidence": [ { "id": "A0A8V0ZJW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZJW0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q66H86-1", "protein_name": "Olfactomedin-like protein 1", "gene_name": "Olfml1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMVALPGASASLVLFLAAFLPPLQHAQDPAMVHYIYQRFQVLEQGLEKCAQTTRAYIQDFQEFSKNLSTMLGRCQTHTNEYRSAVDNLALRVERAQREIDYLQYLRESDFCVESEEKTSAEKVLQEAEEEKKIRTLLNTSCDNMLMAIKSLKIVKKTVDPEGSWMKDAGSTSAKVYLLAGSRNNTVWEFANLRAFMEDSVKPGPRKLTLPLSWQGSGQVVYQSFLFFHNQGTSNEIIKYNLQKKTVEDRMLLPGGAGRAPIYQHSLSTYIDLAVDEHGLWAIHSGPGIQGHLVLTKIEAGTLGIEHSWDTPCRSQDAEASFLLCGVLYVVYSSGGQGPHRITCVYDPLGTVREEHLPNLFFPRRARSHSMIHYNPRDKQLYAWNEGYQIIYKLQTKKKLPLE", "length": 402 }, "evidence": [ { "id": "A0A8V0ZJW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZJW0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6UWY5-1", "protein_name": "Olfactomedin-like protein 1", "gene_name": "OLFML1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMVALRGASALLVLFLAAFLPPPQCTQDPAMVHYIYQRFRVLEQGLEKCTQATRAYIQEFQEFSKNISVMLGRCQTYTSEYKSAVGNLALRVERAQREIDYIQYLREADECIESEDKTLAEMLLQEAEEEKKIRTLLNASCDNMLMGIKSLKIVKKMMDTHGSWMKDAVYNSPKVYLLIGSRNNTVWEFANIRAFMEDNTKPAPRKQILTLSWQGTGQVIYKGFLFFHNQATSNEIIKYNLQKRTVEDRMLLPGGVGRALVYQHSPSTYIDLAVDEHGLWAIHSGPGTHSHLVLTKIEPGTLGVEHSWDTPCRSQDAEASFLLCGVLYVVYSTGGQGPHRITCIYDPLGTISEEDLPNLFFPKRPRSHSMIHYNPRDKQLYAWNEGNQIIYKLQTKRKLPLK", "length": 402 }, "evidence": [ { "id": "A0A8V0ZJW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZJW0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZJW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJW0" }, { "id": "PS51132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Olfactomedin-like", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 395, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 198, "end_pos": 200 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZJZ8-1", "uniprot_ac": "A0A8V0ZJZ8", "uniprot_id": "A0A8V0ZJZ8_CHICK", "mass": { "chemical_mass": 104668.0, "monoisotopic_mass": 104668.0 }, "refseq": { "ac": "NP_001006249", "name": "polyhomeotic-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006249" }, "gene_names": [ { "name": "PHC1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZJZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ] }, { "name": "PHC1", "type": "synonym", "evidence": [ { "id": "NP_001006249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006249" } ] } ], "protein_names": [ { "name": "Polyhomeotic homolog 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZJZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8/entry#names_and_taxonomy" } ] }, { "name": "polyhomeotic-like 1", "type": "synonym", "evidence": [ { "id": "NP_001006249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006249" } ] }, { "name": "polyhomeotic-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_001006249", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006249" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720152.1, SRR13267655.90670.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000015.1. On Sep 23, 2021 this sequence version replaced NP_001006249.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006249", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006249" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PHC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8", "locus": { "chromosome": "1", "start_pos": 76170397, "end_pos": 76150905, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022842", "url": "https://www.ensembl.org/id/ENSGALG00010022842" } ] } } ], "crossref": [ { "id": "A0A8V0ZJZ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZJZ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09577", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09577", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418252", "url": "https://www.ncbi.nlm.nih.gov/gene/418252", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418252", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418252", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QHTNEIN", "url": "https://omabrowser.org/oma/group/QHTNEIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJZ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZJZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS79", "url": "https://www.orthodb.org/?gene=A0A8V0ZS79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16616", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16616", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21319", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21319", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2559580", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559580", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3108214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3899300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4551638", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4570464", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4570464", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8943724", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8953750", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8953750", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001006249", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006249", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METESEQNSGSASGSSNSGGSTRPQISQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLNSAQLHSLAAVQQATIAASRQASSPNTSTPQQTTTTQASINLATTSAAQLISRSQSVSSPTATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPPTQSPGVHADTDQVQNLAVRSQQTSATNAQLQGSAQKAALPGNSQASGLPQATSTGQTVTVAPAPSGSTGQSLNLSQGTAGSNGVSGGVVASSGSQNSTALSQTASAGAAGSCQRKGTGVVQPLPVAAAQAVTVSQGSQTESENAATKKGETDNGGQQTVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQSSSLTQQQQAQPSQQQAPPQNQQQTQTLVVQPMLQSQPQSVQLQHDSPSQPATKSPVPIQSKSMVTSIKPPQLGPAKMSAAQQPPPHIPVQVVGTRQQGSGQAQALGLAQVAAAVPTSRGMPAVVQSVSQVHAPSPPSSAPISSQEAPPLTTGVNLAQVQGTTHMVKNSASSPVVAQMPAAFYMQSLQLPGKSQSLAIKRKAESEEEKEVSASVTALMPARSSPVTDSPKNMEEKNGLGDKSDPAATTTPNATSSEGTSVTSTSVPTANLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQGGTPPGQAENLSSNSPEGDSASMELDKKANLLKCEYCGKYAPATQFRGSKRFCSMTCAKRYNVSCSHQFRLQRKKMKELQEANYARVRRRGSRRSSSEITRTKIQGKRHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRSGHGERDMANSSMAPPTPDLHGINPVFLSSSPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINILKET", "length": 991, "header": "tr|A0A8V0ZJZ8-1|A0A8V0ZJZ8_CHICK Isoform 1 of Polyhomeotic homolog 1 OS=Gallus gallus OX=9031 GN=PHC1 PE=4 SV=1 CANONICAL=A0A8V0ZJZ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8/entry#A0A8V0ZJZ8-1", "sequence": { "sequence": "METESEQNSGSASGSSNSGGSTRPQISQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLNSAQLHSLAAVQQATIAASRQASSPNTSTPQQTTTTQASINLATTSAAQLISRSQSVSSPTATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPPTQSPGVHADTDQVQNLAVRSQQTSATNAQLQGSAQKAALPGNSQASGLPQATSTGQTVTVAPAPSGSTGQSLNLSQGTAGSNGVSGGVVASSGSQNSTALSQTASAGAAGSCQRKGTGVVQPLPVAAAQAVTVSQGSQTESENAATKKGETDNGGQQTVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQSSSLTQQQQAQPSQQQAPPQNQQQTQTLVVQPMLQSQPQSVQLQHDSPSQPATKSPVPIQSKSMVTSIKPPQLGPAKMSAAQQPPPHIPVQVVGTRQQGSGQAQALGLAQVAAAVPTSRGMPAVVQSVSQVHAPSPPSSAPISSQEAPPLTTGVNLAQVQGTTHMVKNSASSPVVAQMPAAFYMQSLQLPGKSQSLAIKRKAESEEEKEVSASVTALMPARSSPVTDSPKNMEEKNGLGDKSDPAATTTPNATSSEGTSVTSTSVPTANLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQGGTPPGQAENLSSNSPEGDSASMELDKKANLLKCEYCGKYAPATQFRGSKRFCSMTCAKRYNVSCSHQFRLQRKKMKELQEANYARVRRRGSRRSSSEITRTKIQGKRHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRSGHGERDMANSSMAPPTPDLHGINPVFLSSSPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINILKET", "length": 991, "header": "tr|A0A8V0ZJZ8-1|A0A8V0ZJZ8_CHICK Isoform 1 of Polyhomeotic homolog 1 OS=Gallus gallus OX=9031 GN=PHC1 PE=4 SV=1 CANONICAL=A0A8V0ZJZ8-1" }, "locus": { "chromosome": "1", "start_pos": 76169327, "end_pos": 76154876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055579.1", "url": "https://www.ensembl.org/id/ENSGALT00010055579.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033679.1", "url": "https://www.ensembl.org/id/ENSGALP00010033679.1" } ] } }, { "isoform_ac": "A0A8V0ZS79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8/entry#A0A8V0ZS79-1", "sequence": { "sequence": "METESEQNSGSASGSSNSGGSTRPQISQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLNSAQLHSLAAVQQATIAASRQASSPNTSTPQQTTTTQASINLATTSAAQLISRSQSVSSPTATTLTQSVLLGNTTSPPLNQSQAQMYLRVQNLAVRSQQTSATNAQLQGSAQKAALPGNSQASGLPQATSTGQTVTVAPAPSGSTGQSLNLSQGTAGSNGVSGGVVASSGSQNSTALSQTASAGAAGSCQRKGTGVVQPLPVAAAQAVTVSQGSQTESENAATKKGETDNGGQQTVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQSSSLTQQQQAQPSQQQAPPQNQQQTQTLVVQPMLQSQPQSVQLQHDSPSQPATKSPVPIQSKSMVTSIKPPQLGPAKMSAAQQPPPHIPVQVVGTRQQGSGQAQALGLAQVAAAVPTSRGMPAVVQSVSQVHAPSPPSSAPISSQEAPPLTTGVNLAQVQGTTHMVKNSASSPVVAQMPAAFYMQSLQLPGKSQSLAIKRKAESEEEKEVSASVTALMPARSSPVTDSPKNMEEKNGLGDKSDPAATTTPNATSSEGTSVTSTSVPTANLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQGGTPPGQAENLSSNSPEGDSASMELDKKANLLKCEYCGKYAPATQFRGSKRFCSMTCAKRYNVSCSHQFRLQRKKMKELQEANYARVRRRGSRRSSSEITRTKIQGKRHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRSGHGERDMANSSMAPPTPDLHGINPVFLSSSPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINILKET", "length": 939, "header": "tr|A0A8V0ZS79-1|A0A8V0ZJZ8_CHICK Computationally mapped isoform of Polyhomeotic homolog 1 OS=Gallus gallus OX=9031 GN=PHC1 PE=4 SV=1 CANONICAL=A0A8V0ZJZ8-1" }, "locus": { "chromosome": "1", "start_pos": 76169327, "end_pos": 76154876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055575.1", "url": "https://www.ensembl.org/id/ENSGALT00010055575.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033678.1", "url": "https://www.ensembl.org/id/ENSGALP00010033678.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 323, "start_aa": "Thr", "end_pos": 323, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr323", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418252", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418252", "resource": "KEGG Pathway" }, { "id": "R-GGA-2559580", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2559580", "resource": "Reactome", "description": "Oxidative Stress Induced Senescence" }, { "id": "R-GGA-3108214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3108214", "resource": "Reactome", "description": "SUMOylation of DNA damage response and repair proteins" }, { "id": "R-GGA-3899300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3899300", "resource": "Reactome", "description": "SUMOylation of transcription cofactors" }, { "id": "R-GGA-4551638", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4551638", "resource": "Reactome", "description": "SUMOylation of chromatin organization proteins" }, { "id": "R-GGA-4570464", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4570464", "resource": "Reactome", "description": "SUMOylation of RNA binding proteins" }, { "id": "R-GGA-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" }, { "id": "R-GGA-8943724", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8943724", "resource": "Reactome", "description": "Regulation of PTEN gene transcription" }, { "id": "R-GGA-8953750", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8953750", "resource": "Reactome", "description": "Transcriptional Regulation by E2F6" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AHM8-1", "protein_name": "Polyhomeotic homolog 1", "gene_name": "Phc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFPQPPRRVQRPGLMGLESEHHSWGPWNAIMETESEQNSSSTNGSSSSGASSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNSSTAQQQTATTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPPAQSPGVHADADQVQNLAVRNQQASAQGPQIPGSTQKAIPPGASPVSGLSQASSQALAVAQASGASGQSLNLSQAGGGSGNSLPGSMGPGGGGQAPGGLGQLPSSGLAGGNCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEGDGSSQQSVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQATTLAAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPEPTPKPPIPIQSKPPVAPIKPPQLGAAKMSATQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGAVQPGQAHLASSQPSSQAPGALQECPPALATGMTLAPVQGTAHVVKGGPTASSPVVAQVPAAFYMQSVHLPGKAQTLAVKRKAESEEEREDLSALGSVLPTKASPAAESPKVIEEKNSLVEKAEPVASLNANPPNSDLVALAPTPSAPPPTLALVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQFLKETEKPLPAGLPTGLNESQSGGPLGGDSPCVDLDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRKKMKEFQEASYARVRRRGPRRSSSDIARAKIQGKRHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNTITTPSTPELQGINPVFLSSNPSQWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET", 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"METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET", "length": 1004 }, "evidence": [ { "id": "A0A8V0ZJZ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZJZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ], "pmid": "" }, { "name": "PRC1 complex", "id": "GO:0035102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ], "pmid": "" }, { "name": "sex chromatin", "id": "GO:0001739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZK24-1", "uniprot_ac": "A0A8V0ZK24", "uniprot_id": "A0A8V0ZK24_CHICK", "mass": { "chemical_mass": 50879.0, "monoisotopic_mass": 50879.0 }, "refseq": {}, "gene_names": [ { "name": "KRT13", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" } ] } ], "protein_names": [ { "name": "Keratin 13", "type": "synonym", "evidence": [ { "id": "A0A8V0ZK24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KRT13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24", "locus": { "chromosome": "27", "start_pos": 4540893, "end_pos": 4546119, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022872", "url": "https://www.ensembl.org/id/ENSGALG00010022872" } ] } } ], "crossref": [ { "id": "A0A8V0ZK24", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZK24", "database": "AlphaFoldDB", "categories": [] }, { "id": "408040", "url": "https://www.ncbi.nlm.nih.gov/gene/408040", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:408040", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:408040", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAKMTGF", "url": "https://omabrowser.org/oma/group/DAKMTGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK24", "url": "https://www.orthodb.org/?gene=A0A8V0ZK24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSB0", "url": "https://www.orthodb.org/?gene=A0A8V0ZSB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTYTVQNSFASGAGGLGAAGSGSSRLSSVRVGGSYRTPSIHGGSGGRGVSISSTKYVSSVGGGYGGGSCAGFGGGYGGGYGGFGGGAVCGLGGGAGFGGGFDAICAFGGGDGLLSGNEKITMQNLNDRLATYLQKVRALEDANAELEVKIRDWYQKEAPSSPARDYSNYYKIIEDLQDKILAATIDNSRVVLEIDNARLAADDFRLKHENELFLRQSVESDINGLRRVLDELTLSRADLEMQIESLKEELAYLKKNHEEEMKEYSNQLSGKVSVEMDAAPGIDLTRILSEMREQYEALAEKYRKDAEAWFLTQTTELNHEVATHTEQIQSSKSEITELRRTMQSLEIELQSQISMKAGLEANLRDTEGRYCAQLAQIQNLITSVEEQLSEIRCDMERQNQEYRMLMDIKSRLEQEIATYRQLLETQDSHLMIFFSPTTASAAGRARGGTEDEGRSSSTRDRRHQ", "length": 465, "header": "tr|A0A8V0ZK24-1|A0A8V0ZK24_CHICK Isoform 1 of Keratin 13 OS=Gallus gallus OX=9031 GN=KRT13 PE=1 SV=1 CANONICAL=A0A8V0ZK24-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZK24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24/entry#A0A8V0ZK24-1", "sequence": { "sequence": "MTTYTVQNSFASGAGGLGAAGSGSSRLSSVRVGGSYRTPSIHGGSGGRGVSISSTKYVSSVGGGYGGGSCAGFGGGYGGGYGGFGGGAVCGLGGGAGFGGGFDAICAFGGGDGLLSGNEKITMQNLNDRLATYLQKVRALEDANAELEVKIRDWYQKEAPSSPARDYSNYYKIIEDLQDKILAATIDNSRVVLEIDNARLAADDFRLKHENELFLRQSVESDINGLRRVLDELTLSRADLEMQIESLKEELAYLKKNHEEEMKEYSNQLSGKVSVEMDAAPGIDLTRILSEMREQYEALAEKYRKDAEAWFLTQTTELNHEVATHTEQIQSSKSEITELRRTMQSLEIELQSQISMKAGLEANLRDTEGRYCAQLAQIQNLITSVEEQLSEIRCDMERQNQEYRMLMDIKSRLEQEIATYRQLLETQDSHLMIFFSPTTASAAGRARGGTEDEGRSSSTRDRRHQ", "length": 465, "header": "tr|A0A8V0ZK24-1|A0A8V0ZK24_CHICK Isoform 1 of Keratin 13 OS=Gallus gallus OX=9031 GN=KRT13 PE=1 SV=1 CANONICAL=A0A8V0ZK24-1" }, "locus": { "chromosome": "27", "start_pos": 4545263, "end_pos": 4541178, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055654.1", "url": "https://www.ensembl.org/id/ENSGALT00010055654.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033709.1", "url": "https://www.ensembl.org/id/ENSGALP00010033709.1" } ] } }, { "isoform_ac": "A0A8V0ZSB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24/entry#A0A8V0ZSB0-1", "sequence": { "sequence": "MTTYTVQNSFASGAGGLGAAGSGSSRLSSVRVGGSYRTPSIHGGSGGRGVSISSTKYVSSVGGGYGGGSCAGFGGGYGGGYGGFGGGAVCGLGGGAGFGGGFDAICAFGGGDGLLSGNEKITMQNLNDRLATYLQKVRALEDANAELEVKIRDWYQKEAPSSPARDYSNYYKIIEDLQDKILAATIDNSRVVLEIDNARLAADDFRLKHENELFLRQSVESDINGLRRVLDELTLSRADLEMQIESLKEELAYLKKNHEEEMKEYSNQLSGKVSVEMDAAPGIDLTRILSEMREQYEALAEKYRKDAEAWFLTQTTELNHEVATHTEQIQSSKSEITELRRTMQSLEIELQSQISMKAGLEANLRDTEGRYCAQLAQIQNLITSVEEQLSEIRCDMERQNQEYRMLMDIKSRLEQEIATYRQLLETQDSQMSGVNPKDASAAGRARGGTEDEGRSSSTRDRRHQ", "length": 464, "header": "tr|A0A8V0ZSB0-1|A0A8V0ZK24_CHICK Computationally mapped isoform of Keratin 13 OS=Gallus gallus OX=9031 GN=KRT13 PE=1 SV=1 CANONICAL=A0A8V0ZK24-1" }, "locus": { "chromosome": "27", "start_pos": 4545263, "end_pos": 4541178, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055661.1", "url": "https://www.ensembl.org/id/ENSGALT00010055661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033713.1", "url": "https://www.ensembl.org/id/ENSGALP00010033713.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:408040", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:408040", "resource": "KEGG Pathway" }, { "id": "R-GGA-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-GGA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QXD3-1", "protein_name": "Keratin 15", "gene_name": "LOC100515166", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCRLQSSSASYGGGFGGGSCQLGGGRSISTCSSRFVSGGSTGGYGGGVSCGFGGGAGSGFGAGFGGGFGGSFGGGFGGGVAGGFGFGDFGGGDGGLLAGNEKITMQNLNDRLASYLEKVRALEEANTDLEVKIRDWYQKQSPSSPERDYSPYFKTIEELRDKIQAANIENNRVVLQIDNARLAADDFRLKYENELTLRQSVEADINGLRRVLDELTLTKTDLEMQIESLNEELAFLKKNHEEEMKEFSNRVVGQVNVEMDATPGVDLTRVLAEMREQYEAMAEKNRREAEEWFNKKIEELNKEVISSTALIQTSKTEITELRRTLQGLEIELQSQLSTKAGLENSLAETECRYALQLQQIQGLIGSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDANLNVFCSLRFPGNVTHSATITASTTISSSGSSNGPTRRTLESSRS", "length": 457 }, "evidence": [ { "id": "A0A8V0ZK24", "url": "https://omabrowser.org/oma/group/A0A8V0ZK24/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I8F5-1", "protein_name": "Keratin, type I cytoskeletal 13", "gene_name": "Krt13", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSCRFQSSSTSYGGGFGAGSCQLGGGRKISTCSSRFASGGSAGGYGGGMSCGFGGGAGSGFGGGFGGSYGGGFGGGFGGGFGGGFGDFGGGDGGLLSGNEKITMQNLNDRLANYLEKVRALEAANADLEVKIRDWHLRQSPTSPERDYSAYYKTIEELRVKILEATTDNNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEALAEKNRRDAEQWFQNKSAELNKEVSSNAAMIQTSKTEITELRRTLQSLEIELQSQLSMKAGLESTLAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMTGFNNSGGTSTASNASSSPSTSGRLDFRKY", "length": 442 }, "evidence": [ { "id": "A0A8V0ZK24", "url": "https://omabrowser.org/oma/group/A0A8V0ZK24/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P08730-1", "protein_name": "Keratin, type I cytoskeletal 13", "gene_name": "Krt13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCRFQSSSMSYGGGFGAGSCQLGGGRNISSCSSRFVTGGSAGGYGGGMSCGFGGGAGGGFGGGFGGGFGGSYGGGFGGGFGDFGGVDGGLLSGNEKITMQNLNDRLASYLDKVRALEAANADLEVKIRDWHLKQSPASPERDYSAYYKTIEELRIKILEATTDNNRIILEIDNARLAADDFRLKYENELTLRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEALAEKNRRDAEEWFQTKSAELNKEVSSNAEMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLESTLAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMTGFNSGGNNTTTSNGSPSSNSGRPDFRKY", "length": 437 }, "evidence": [ { "id": "A0A8V0ZK24", "url": "https://omabrowser.org/oma/group/A0A8V0ZK24/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13646-1", "protein_name": "Keratin, type I cytoskeletal 13", "gene_name": "KRT13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHTKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGRRTSDVRRP", "length": 458 }, "evidence": [ { "id": "A0A8V0ZK24", "url": "https://omabrowser.org/oma/group/A0A8V0ZK24/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6IFV4-1", "protein_name": "Keratin, type I cytoskeletal 13", "gene_name": "Krt13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSCRFQSSSMSYGGGFGAGSCQLGGGRNISTCSSRFVTGGSSGGYGGGMSCGFGGGAGGGYGGGFGGGFGGSCGGGFGGGFGDFGSVDGGLLSGNEKITMQNLNDRLASYLEKVRALEAANADLEVKIRDWHLKQSPTSPERDYSAYYKTIEELRIKILEATTDNNRIVLEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLAKTDLEMQIESLNEELAYLKKNHEEEMKEFSNQAVGQVNVEMDATPGIDLTRVLAEMREQYEALAEKNRRDAEAWFQAKSAELNKEVSSNAAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLESTLAETECRYALQLQQIQALISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMTGFNTGGNSTTTSNTSTSPSTSGRPDFRKY", "length": 438 }, "evidence": [ { "id": "A0A8V0ZK24", "url": "https://omabrowser.org/oma/group/A0A8V0ZK24/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" } ], "pmid": "" }, { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" } ], "pmid": "" }, { "name": "morphogenesis of an epithelium", "id": "GO:0002009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "scaffold protein binding", "id": "GO:0097110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" } ], "pmid": "" }, { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZK24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK24" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 431, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZK27-1", "uniprot_ac": "A0A8V0ZK27", "uniprot_id": "A0A8V0ZK27_CHICK", "mass": { "chemical_mass": 65900.0, "monoisotopic_mass": 65900.0 }, "refseq": { "ac": "NP_001382147", "name": "solute carrier family 23 member 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382147" }, "gene_names": [ { "name": "SLC23A3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK27" } ] }, { "name": "SLC23A3", "type": "synonym", "evidence": [ { "id": "NP_001382147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382147" } ] } ], "protein_names": [ { "name": "Solute carrier family 23 member 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZK27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK27/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 23 (nucleobase transporters), member 3", "type": "synonym", "evidence": [ { "id": "NP_001382147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382147" } ] }, { "name": "solute carrier family 23 member 3", "type": "synonym", "evidence": [ { "id": "NP_001382147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382147" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001382147", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382147" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK27" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC23A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK27", "locus": { "chromosome": "7", "start_pos": 21888841, "end_pos": 21884398, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021501", "url": "https://www.ensembl.org/id/ENSGALG00010021501" } ] } } ], "crossref": [ { "id": "A0A8V0ZK27", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZK27", "database": "AlphaFoldDB", "categories": [] }, { "id": "429039", "url": "https://www.ncbi.nlm.nih.gov/gene/429039", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LTWGLSC", "url": "https://omabrowser.org/oma/group/LTWGLSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK27", "url": "https://www.orthodb.org/?gene=A0A8V0ZK27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00860", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00860", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001382147", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382147", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK27-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGGSSMNGGRHPVTGAGSPALTSCSWPKMCSWTLSCCLALQHLAVQASLLCIFHLLLLPALSEEQLHIPAASVLLARSLFACGISTLLQTTLGSRLPLVQIPSFEYLVPALVLSSHLSLGVSEDGNGMAVATVCPEPHCTIMESRATSLQEVSGAVLISGLVQLVLGALGVCGWAVQRCGPMVLAPSLSIIGLSAYKEAAFFCSANWGVALLLMLLTITFSQHLGSCRLPFCAWPYAPGVSVEPSVPTLRTLSVLLPFAIVCIVCSIVHHFHVSWDLPDLATAQLSWVNSTLRAPWLQLPYAGEWPLLTPRALAVGIAMAFGCSINSVGCYVLCGRLLRAPQPPSHTCNRGLCIEGLGSLLAGLLGSAGGTAASIANACAGGLTQDGSRLSVQLNALACVMLGMSPRLVGLLAHIPLAVHGGVLCVTYAVAVGTGISYFQYADIDSGRNIFIVGFTMFMALLVPRWLSVAPARLVTGWVPLDLLFLSLLVMPVFLTGFLSFFLENTVSGTLEERGLLADRVQRKPGTSSGQPWREESKASPVYGLPTRLRRLLPSSCKAFPCCFLCPGSEDEKEEEEDGGRVAEEGMAAAGEGTHLLLKPGTGDMQADRQPSQAEMLAWHTGA", "length": 624, "header": "tr|A0A8V0ZK27-1|A0A8V0ZK27_CHICK Isoform 1 of Solute carrier family 23 member 3 OS=Gallus gallus OX=9031 GN=SLC23A3 PE=3 SV=1 CANONICAL=A0A8V0ZK27-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZK27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK27/entry#A0A8V0ZK27-1", "sequence": { "sequence": "MRGGSSMNGGRHPVTGAGSPALTSCSWPKMCSWTLSCCLALQHLAVQASLLCIFHLLLLPALSEEQLHIPAASVLLARSLFACGISTLLQTTLGSRLPLVQIPSFEYLVPALVLSSHLSLGVSEDGNGMAVATVCPEPHCTIMESRATSLQEVSGAVLISGLVQLVLGALGVCGWAVQRCGPMVLAPSLSIIGLSAYKEAAFFCSANWGVALLLMLLTITFSQHLGSCRLPFCAWPYAPGVSVEPSVPTLRTLSVLLPFAIVCIVCSIVHHFHVSWDLPDLATAQLSWVNSTLRAPWLQLPYAGEWPLLTPRALAVGIAMAFGCSINSVGCYVLCGRLLRAPQPPSHTCNRGLCIEGLGSLLAGLLGSAGGTAASIANACAGGLTQDGSRLSVQLNALACVMLGMSPRLVGLLAHIPLAVHGGVLCVTYAVAVGTGISYFQYADIDSGRNIFIVGFTMFMALLVPRWLSVAPARLVTGWVPLDLLFLSLLVMPVFLTGFLSFFLENTVSGTLEERGLLADRVQRKPGTSSGQPWREESKASPVYGLPTRLRRLLPSSCKAFPCCFLCPGSEDEKEEEEDGGRVAEEGMAAAGEGTHLLLKPGTGDMQADRQPSQAEMLAWHTGA", "length": 624, "header": "tr|A0A8V0ZK27-1|A0A8V0ZK27_CHICK Isoform 1 of Solute carrier family 23 member 3 OS=Gallus gallus OX=9031 GN=SLC23A3 PE=3 SV=1 CANONICAL=A0A8V0ZK27-1" }, "locus": { "chromosome": "7", "start_pos": 21888676, "end_pos": 21884451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052137.1", "url": "https://www.ensembl.org/id/ENSGALT00010052137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031137.1", "url": "https://www.ensembl.org/id/ENSGALP00010031137.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TTJ2-1", "protein_name": "Solute carrier family 23 member 3", "gene_name": "SLC23A3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQSPPNAIQLQSVGSQGTLATLPRPPDVQNPSSDSWASLSGPPPWGLSCLLALQHILVLASLLCASHLLLLQSLPAGGLSFSPAQLLASSLFACGVSTSLQTWMGSRLPLVQAPSLQFLIPALVLTSQKLPLALRTPGNCEHRARAQASLVLRLCGGPGCHGLELWNTSIREVSGAVVVSGLLQAILGLLGGPGHLFPRCGPLVLAPSLVVAGLSVYREVALLCSTHWGLASLLIVLMVVCSQHLGSCLLPPRHWRPASTSSTHTHILAFRLLSVLIPVACVWIVSALLGLSIIPGELSAPTKAPWFWLPHPAEWDWPLLTPRALAAGISMALAASTSSLGCYALCGQLLRLPSPPPHACSRGLSLEGLGSVLAGLLGSPMGTASSFPNVGTVGLLQAGPRRVAHLVGLFCMALGLSPRLAQLLTTIPLPVLGGVLGVTQAMVLSTGFSSFHLADIDSGRNVFIVGFSIFMALLLPRWFREASVLLKTGWSPLDVLLRSLLTEPIFLAGLLGFLLENTIPGTRLERGLGQGLPPPFTAREAPMPQKSREKADQEYELPFSIQNLCPCIPQPLRCLCPLPQDSGNEERGPSEPGETADLLPDFGDQCPQPSRGQSQL", "length": 617 }, "evidence": [ { "id": "A0A8V0ZK27", "url": "https://omabrowser.org/oma/group/A0A8V0ZK27/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZG28-1", "protein_name": "Solute carrier family 23, member 3", "gene_name": "Slc23a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSPPHPIPLLSVGSQDTPAPRPPLLPPLQDPSSRSWASWCGPSTWGLSCLLALQHFLVLTSLLWASHLLLLHSLPPGGLSYPPAQLLASSFFSCGMSTVLQTWMGSRLPLIQAPSLEFLIPALVLTNQKLPLMTKTPGNASLSLRLCSLTRSCHGPELWNTSLREVSGAVVMSGLLQGTMGLLGVPGRVFPYCGPLVLAPSLVVAGLSAHKEVAQFCSAHWGLALLLILLMVVCSQHLGSCQVPLCSWRPASTSSTHIYIPIFRLLSVLAPVACVWLISACLGLSVIPLQLSEPSDAPWFWLPHPGEWEWPLLTPKALAAGISMALAASTSSLGCYALCGQLLHLSPPPPHACSRGLSLEGLGSVLAGLLGSPLGTASSFPNVGTVSLFQTGSRRVAHLVGLFCMGLGLSPRLAQLFTNIPLPVLGGVLGVTQAVVLSAGFSSFHLADIDSGRNVFIVGFSIFMALLLPRWLREAPILLNTGWSPMDMFLRSLLAEPIFLAGLLGFLLENTISGTRIERGLGQALPTSFTAQETQMLQKSRKKAAQEYGLPLSIKNLCSCIPQPLRCLCPMPEDSGDEGGSSKTGETADLLPNSGESSSPDGREGFRS", "length": 610 }, "evidence": [ { "id": "A0A8V0ZK27", "url": "https://omabrowser.org/oma/group/A0A8V0ZK27/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60850-1", "protein_name": "Solute carrier family 23 member 3", "gene_name": "Slc23a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRSPLHPIPLLSEGYQDTPAPLPPLLPPLQNPSSRSWASRVFGPSTWGLSCLLALQHFLVLASLLWASHLLLLHGLPPGGLSYPPAQLLASSFFSCGLSTVLQTWMGSRLPLIQAPSLEFLIPALVLTNQKLPLTTKTPGNASLSLPLCSLTRSCHGLELWNTSLREVSGAVVVSGLLQGTIGLLGVPGRVFPYCGPLVLAPSLVVAGLSAHKEVAQFCSAHWGLALLLILLMVVCSQHLGSCQIPLCSWRPSSTSTHICIPVFRLLSVLAPVACVWFISAFVGTSVIPLQLSEPSDAPWFWLPHPGEWEWPLLTPRALAAGISMALAASTSSLGCYALCGQLLRLSPPPPHACSRGLSLEGLGSVLAGLLGSPLGTASSFPNVGTVSLFQTGSRRVAHLVGLFCMGLGLSPRLAQLFTSIPLPVLGGVLGVTQAVVLSAGFSSFHLADIDSGRNVFIVGFSIFMALLLPRWLREAPVLLNTGWSPLDMFLRSLLAEPIFLAGLLGFLLENTISGTRAERGLGQRLPTSFTAQEIQMLQQSRRKAAQEYGLPLPIKNLCSCIPQPLHCLCPMPEDSGDEGGSSKTGERADLLPNSGESYSTASREGVRSQ", "length": 611 }, "evidence": [ { "id": "A0A8V0ZK27", "url": "https://omabrowser.org/oma/group/A0A8V0ZK27/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PIS1-1", "protein_name": "Solute carrier family 23 member 3", "gene_name": "SLC23A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSPLNPSQLRSVGSQDALAPLPPPAPQNPSTHSWDPLCGSLPWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQLLASSFFSCGMSTILQTWMGSRLPLVQAPSLEFLIPALVLTSQKLPRAIQTPGNSSLMLHLCRGPSCHGLGHWNTSLQEVSGAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLAPSLVVAGLSAHREVAQFCFTHWGLALLVILLMVVCSQHLGSCQFHVCPWRRASTSSTHTPLPVFRLLSVLIPVACVWIVSAFVGFSVIPQELSAPTKAPWIWLPHPGEWNWPLLTPRALAAGISMALAASTSSLGCYALCGRLLHLPPPPPHACSRGLSLEGLGSVLAGLLGSPMGTASSFPNVGKVGLIQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVVGGVLGVTQAVVLSAGFSSFYLADIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSPLDVLLHSLLTQPIFLAGLSGFLLENTIPGTQLERGLGQGLPSPFTAQEARMPQKPREKAAQVYRLPFPIQNLCPCIPQPLHCLCPLPEDPGDEEGGSSEPEEMADLLPGSGEPCPESSREGFRSQK", "length": 610 }, "evidence": [ { "id": "A0A8V0ZK27", "url": "https://omabrowser.org/oma/group/A0A8V0ZK27/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK27" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "hypoxanthine transport", "id": "GO:0035344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035344", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 290, "end_pos": 292 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015142804", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015142804" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK82" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SRSF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK82", "locus": { "chromosome": "5", "start_pos": 27392314, "end_pos": 27396920, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021516", "url": "https://www.ensembl.org/id/ENSGALG00010021516" } ] } } ], "crossref": [ { "id": "A0A8V0ZK82", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZK82", "database": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZK49-1", "uniprot_ac": "A0A8V0ZK49", "uniprot_id": "A0A8V0ZK49_CHICK", "mass": { "chemical_mass": 71355.0, "monoisotopic_mass": 71355.0 }, "refseq": {}, "gene_names": [ { "name": "UNC93B1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ] } ], "protein_names": [ { "name": "Unc-93 homolog B1, TLR signaling regulator", "type": "synonym", "evidence": [ { "id": "A0A8V0ZK49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UNC93B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49", "locus": { "chromosome": "5", "start_pos": 518317, "end_pos": 514241, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021493", "url": "https://www.ensembl.org/id/ENSGALG00010021493" } ] } } ], "crossref": [ { "id": "A0A8V0ZK49", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZK49", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17408", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17408", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395244", "url": "https://www.ncbi.nlm.nih.gov/gene/395244", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395244", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395244", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IFYGFFH", "url": "https://omabrowser.org/oma/group/IFYGFFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK49", "url": "https://www.orthodb.org/?gene=A0A8V0ZK49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQW7", "url": "https://www.orthodb.org/?gene=A0A8V0ZQW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46744", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46744", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46744:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46744:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1679131", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1679131", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQW7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGTEQSCQTPSWLPFLGCWRRQRHTSRGDIGGDGKGDTWMTRGHKQTECPTDAAAMEKDPSCCQDAAKTAAGEMLGPEAQLDDIVGAHTDYNEEEEEQKYFRRKRLGVVKNVLAASLAAMLTYSVYLGLLQMQLILHYDETYREVKYSNMELEDIDRKVLMGINVTPVVALLYTPVLIRFFGTKWTMFLAVGIYALFVSSNYWERYFTLVPSAVAIGVAIVPFWASLGNYITRMAQKYYEYANYKEEHVQEQRQAPRGACSAYIVVFQTIFYICFHLSFVCAQMPMLFFLNNYIYQLNHTLSGVKHCGTLSHGMLTGFNKTVLDSLPRSVNLIMVESVLMAAAFLAMLMVLLLCGSAYGTTEEIDLRSIGWGNIFQLPFKHMRDYRLRHLLPFFIYSGFEVLFVCNDFSLNYGVCTLGLEKLAYLLIAYGFSASTCSSLALCMLRLRRQYPLLAGALLHAAILVMLFCWAPKPQQVEQAPLLYTIAALWGMGSALNKTGISILLGMLYEDKERQDFIFTIYHWWQALAIFTVYLWSGLPMKAKLSLMLLALGLAAGSYIWMERRLAQRVAFRLPRMPRPRHRASGYRYLEEDSDETNSEDEGTSRDNSQHPAEEDETPRDDGEQRN", "length": 627, "header": "tr|A0A8V0ZK49-1|A0A8V0ZK49_CHICK Isoform 1 of Unc-93 homolog B1, TLR signaling regulator OS=Gallus gallus OX=9031 GN=UNC93B1 PE=1 SV=1 CANONICAL=A0A8V0ZK49-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZK49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49/entry#A0A8V0ZK49-1", "sequence": { "sequence": "MTGTEQSCQTPSWLPFLGCWRRQRHTSRGDIGGDGKGDTWMTRGHKQTECPTDAAAMEKDPSCCQDAAKTAAGEMLGPEAQLDDIVGAHTDYNEEEEEQKYFRRKRLGVVKNVLAASLAAMLTYSVYLGLLQMQLILHYDETYREVKYSNMELEDIDRKVLMGINVTPVVALLYTPVLIRFFGTKWTMFLAVGIYALFVSSNYWERYFTLVPSAVAIGVAIVPFWASLGNYITRMAQKYYEYANYKEEHVQEQRQAPRGACSAYIVVFQTIFYICFHLSFVCAQMPMLFFLNNYIYQLNHTLSGVKHCGTLSHGMLTGFNKTVLDSLPRSVNLIMVESVLMAAAFLAMLMVLLLCGSAYGTTEEIDLRSIGWGNIFQLPFKHMRDYRLRHLLPFFIYSGFEVLFVCNDFSLNYGVCTLGLEKLAYLLIAYGFSASTCSSLALCMLRLRRQYPLLAGALLHAAILVMLFCWAPKPQQVEQAPLLYTIAALWGMGSALNKTGISILLGMLYEDKERQDFIFTIYHWWQALAIFTVYLWSGLPMKAKLSLMLLALGLAAGSYIWMERRLAQRVAFRLPRMPRPRHRASGYRYLEEDSDETNSEDEGTSRDNSQHPAEEDETPRDDGEQRN", "length": 627, "header": "tr|A0A8V0ZK49-1|A0A8V0ZK49_CHICK Isoform 1 of Unc-93 homolog B1, TLR signaling regulator OS=Gallus gallus OX=9031 GN=UNC93B1 PE=1 SV=1 CANONICAL=A0A8V0ZK49-1" }, "locus": { "chromosome": "5", "start_pos": 518145, "end_pos": 514321, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052129.1", "url": "https://www.ensembl.org/id/ENSGALT00010052129.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031131.1", "url": "https://www.ensembl.org/id/ENSGALP00010031131.1" } ] } }, { "isoform_ac": "A0A8V0ZQW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49/entry#A0A8V0ZQW7-1", "sequence": { "sequence": "MEKDPSCCQDAAKTAAGEMLGPEAQLDDIVGAHTDYNEEEEEQKYFRRKRLGVVKNVLAASLAAMLTYSVYLGLLQMQLILHYDETYREVKYSNMELEDIDRKVLMGINVTPVVALLYTPVLIRFFGTKWTMFLAVGIYALFVSSNYWERYFTLVPSAVAIGVAIVPFWASLGNYITRMAQKYYEYANYKEEHVQEQRQAPRGACSAYIVVFQTIFYICFHLSFVCAQMPMLFFLNNYIYQLNHTLSGVKHCGTLSHGMLTGFNKTVLDSLPRSVNLIMVESVLMAAAFLAMLMVLLLCGSAYGTTEEIDLRSIGWGNIFQLPFKHMRDYRLRHLLPFFIYSGFEVLFVCNDFSLNYGVCTLGLEKLAYLLIAYGFSASTCSSLALCMLRLRRQYPLLAGALLHAAILVMLFCWAPKPQQVEQAPLLYTIAALWGMGSALNKTGISILLGMLYEDKERQDFIFTIYHWWQALAIFTVYLWSGLPMKAKLSLMLLALGLAAGSYIWMERRLAQRVAFRLPRMPRPRHRASGYRYLEEDSDETNSEDEGTSRDNSQHPAEEDETPRDDGEQRN", "length": 571, "header": "tr|A0A8V0ZQW7-1|A0A8V0ZQW7_CHICK Computationally mapped isoform of Unc-93 homolog B1, TLR signaling regulator OS=Gallus gallus OX=9031 GN=UNC93B1 PE=1 SV=1 CANONICAL=A0A8V0ZK49-1" }, "locus": { "chromosome": "5", "start_pos": 518145, "end_pos": 515242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052127.1", "url": "https://www.ensembl.org/id/ENSGALT00010052127.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031129.1", "url": "https://www.ensembl.org/id/ENSGALP00010031129.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 52, "start_aa": "Thr", "end_pos": 52, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr52", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395244", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395244", "resource": "KEGG Pathway" }, { "id": "R-GGA-1679131", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1679131", "resource": "Reactome", "description": "Trafficking and processing of endosomal TLR" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G901-1", "protein_name": "Protein unc-93 homolog B1", "gene_name": "Unc93b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACAKYHCSHAALSTRRCVCVHPLLDEPECALLLGHLGALMLLDELVGAYPNYNEEEEERRYYRRKRLGVVKNVLAASTGGTLTYGVYLGLLQMQLILHYDETYREVKYGNMGLPDIDSKMLMGINVTPIAALLYTPVLIRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSAVALGMAIVPLWASMGNYITRMSQKYYEYSHYKEQDEQGPQQRPPRGSHAPYLLVFQAIFYSFFHLSFACAQLPMVYFLNHYLYDLNHTLFNVKSCGTKSYGILNGFNKTVLRTLPRSRNLIVVESVLMAVAFLAMLLVLGLCGAAYRPTEEIDLRSVGWGNIFQLPFKHVRDFRLRHLVPFFIYSGFEVLFACTGFTLGYGVCSMGLERLAYLLIAYSLGASAASVLGLLGLWLPRSVPLVAGAGLHLLLTLSLFFWAPAPRVLQHSWIFYFVAALWGVGSALNKTGLSTLLGILYEDKERQDFIFTIYHWWQAVAIFVVYLGSSLPMKAKLAVLLVTLVAAATSYLWMENKLQQGLVPRQPRIPKPQHKVRGYRYLEEDNSDESDVEGEQGQGDCAEEEAPQAGPLGAEPAGPCRRPCPYEQALGGDGPEEQ", "length": 608 }, "evidence": [ { "id": "A0A8V0ZK49", "url": "https://omabrowser.org/oma/group/A0A8V0ZK49/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VCW4-1", "protein_name": "Protein unc-93 homolog B1", "gene_name": "Unc93b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVEPPLYPVAGAAGPQGDEDRHGVPDGPEAPLDELVGAYPNYNEEEEERRYYRRKRLGVVKNVLAASTGVTLTYGVYLGLLQMQLILHYDETYREVKYGNMGLPDIDSKMLMGINVTPIAALLYTPVLIRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSAVALGMAIVPLWASMGNYITRMSQKYYEYSHYKEQDEQGPQQRPPRGSHAPYLLVFQAIFYSFFHLSFACAQLPMIYFLNNYLYDLNHTLINVQSCGTKSQGILNGFNKTVLRTLPRSKNLIVVESVLMAVAFLAMLMVLGLCGAAYRPTEEIDLRSVGWGNIFQLPFKHVRDFRLRHLVPFFIYSGFEVLFACTGFALGYGVCSMGLERLAYLLIAYSLGASASSVLGLLGLWLPRSVPLVAGAGLHLLLTLSLFFWAPAPRVLQHSWIFYFVAALWGVGSALNKTGLSTLLGILYEDKERQDFIFTIYHWWQAVAIFVVYLGSSLPMKAKLAVLLVTLVAAAASYLWMEQKLQQGLVPRQPRIPKPQHKVRGYRYLEEDNSDESDMEGEQGQGDCAEDEAPQAGPLGAEPAGPCRKPCPYEQALGGDGPEEQ", "length": 598 }, "evidence": [ { "id": "A0A8V0ZK49", "url": "https://omabrowser.org/oma/group/A0A8V0ZK49/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H1C4-1", "protein_name": "Protein unc-93 homolog B1", "gene_name": "UNC93B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAEPPLYPMAGAAGPQGDEDLLGVPDGPEAPLDELVGAYPNYNEEEEERRYYRRKRLGVLKNVLAASAGGMLTYGVYLGLLQMQLILHYDETYREVKYGNMGLPDIDSKMLMGINVTPIAALLYTPVLIRFFGTKWMMFLAVGIYALFVSTNYWERYYTLVPSAVALGMAIVPLWASMGNYITRMAQKYHEYSHYKEQDGQGMKQRPPRGSHAPYLLVFQAIFYSFFHLSFACAQLPMIYFLNHYLYDLNHTLYNVQSCGTNSHGILSGFNKTVLRTLPRSGNLIVVESVLMAVAFLAMLLVLGLCGAAYRPTEEIDLRSVGWGNIFQLPFKHVRDYRLRHLVPFFIYSGFEVLFACTGIALGYGVCSVGLERLAYLLVAYSLGASAASLLGLLGLWLPRPVPLVAGAGVHLLLTFILFFWAPVPRVLQHSWILYVAAALWGVGSALNKTGLSTLLGILYEDKERQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAVLLVTLVAAAVSYLRMEQKLRRGVAPRQPRIPRPQHKVRGYRYLEEDNSDESDAEGEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYEQAQGGDGPEEQ", "length": 597 }, "evidence": [ { "id": "A0A8V0ZK49", "url": "https://omabrowser.org/oma/group/A0A8V0ZK49/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "pmid": "" }, { "name": "early phagosome", "id": "GO:0032009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "pmid": "" }, { "name": "toll-like receptor signaling pathway", "id": "GO:0002224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "pmid": "" }, { "name": "toll-like receptor 7 signaling pathway", "id": "GO:0034154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "pmid": "" }, { "name": "toll-like receptor 9 signaling pathway", "id": "GO:0034162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "pmid": "" }, { "name": "toll-like receptor 3 signaling pathway", "id": "GO:0034138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034138", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "Toll-like receptor binding", "id": "GO:0035325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 52 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 299, "end_pos": 301 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 497, "end_pos": 499 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZK51-1", "uniprot_ac": "A0A8V0ZK51", "uniprot_id": "A0A8V0ZK51_CHICK", "mass": { "chemical_mass": 146989.0, "monoisotopic_mass": 146989.0 }, "refseq": { "ac": "XP_040531242", "name": "myopalladin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531242" }, "gene_names": [ { "name": "MYPN", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" } ] }, { "name": "MYPN", "type": "synonym", "evidence": [ { "id": "XP_040531242", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531242" } ] } ], "protein_names": [ { "name": "Myopalladin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51/entry#names_and_taxonomy" } ] }, { "name": "myopalladin", "type": "synonym", "evidence": [ { "id": "XP_040531242", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531242" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052578.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040531242", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531242" } ] }, { "annotation": "Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51#function" }, { "database": "UniProtKB", "id": "ARBA00058480", "url": "https://www.uniprot.org/uniprotkb/ARBA00058480#function" }, { "database": "UniProtKB", "id": "A0A8V0ZT94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT94#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYPN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51", "locus": { "chromosome": "6", "start_pos": 11293609, "end_pos": 11240458, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022890", "url": "https://www.ensembl.org/id/ENSGALG00010022890" } ] } } ], "crossref": [ { "id": "cd20972", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20972", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423684", "url": "https://www.ncbi.nlm.nih.gov/gene/423684", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DEMDHKP", "url": "https://omabrowser.org/oma/group/DEMDHKP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK51", "url": "https://www.orthodb.org/?gene=A0A8V0ZK51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT94", "url": "https://www.orthodb.org/?gene=A0A8V0ZT94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47633:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47633:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040531242", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531242", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQDDSLESSTSISQLLRESYLAETKHQGNSERSRSEPTSHNFLYGNSSGDSDEVVAQDDLPDLSAFLSQEELNESVNLARQAIDQNPLEAKQDELHPPDQLKNTGKKKQMAHSTALRTSDNGLPANFCQDRATDAKGSKGSPQDLKKHLPSESESKKEFLNKAADFIEELSSLFKAHNSERIRPRTCKNYRSKIDSKSKSAQKASSSLSGTSENRERLSIPLPLDLENKSEEAFEKLDDQLTEHSESINQLTSAELKTESESAYSDEPLGQPPRFTQKLKSREVPEGTKVQLDCIVVGIPTPEVRWYCEGKELENSPDIQIIQTGDQHSLVIVEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGASSSDSEGETKDEMEHNLKPADTSLKVAPPATRAATKPQETCKAPSAAVQPVSVPIQSVPTPVNQAESPTNYLQGLDGRPIVAAPVFTKMLQDISASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFSEDSGSFTCTASNKYGTVSSIAQLSVKASEDSNNAAALHTMSSINSVAAENQSPPHNPSQRVGSENPKPKLEGVLVNHNEPRSSSKIGLRVHFKLPEDDKGSESPPEDGLGTTNKTRPSYFHDKINGQPVKIPEPTSPSKEPPPVLAKPKLDLTQLKQLHNQVLLEQQQVHQTSSRDLSFNTTLLNSATSLNQQSTSTTYKQSKASVSQAFSYTRPKQFLPPQTTPPIISSSSSSVTIFSSVSQGIQRTNSRENVTGNPPPVQSRSSGGFTGKSEQSSPSPKESTVPLTLSTSSVKQFQPQSVTPAPVSPTGWIQNPVAFLSAVLPSLPSPPSTNAMGLPRSTPVTSTPGVTKKNPKPLQLPTDESIRENKAALVKDLERKLHFREDINQQSSQQEYRISSFEQRLMNEIEFRLERTPVDESDDEIQHEEIPTGKYIAPIFDKRLKHFRVMEGSPTTFTCKIVGIPVPKIYWFKDGKQISKKNTHYKMSREEDGTCSLHIEAATNDDDGNYTIMAANPQGRVSCSGHLMVQSIPVRGRLSTLQPHRARPRVPEGGDKEAVQERFFRPYFLQAPGDMVAHEGRLCRLDCKVSGLPTPDLTWLLNGKPVLPDGTHKMLVRETGVHSLLIDPLSQNDAGTYTCLATNKTGQNSFSLELTVVAKEVKKAPMFLEKLQNCGVPEGYPVRLECRVVGMPPPVFYWKKDNETIPSNRERMSMHQDTTGYVCLLIQPARKADAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPQQIKLRPGSSRYANLTGQGLDIYSGFPTTESPVLFSSPTQKMVESDEL", "length": 1334, "header": "tr|A0A8V0ZK51-1|A0A8V0ZK51_CHICK Isoform 1 of Myopalladin OS=Gallus gallus OX=9031 GN=MYPN PE=3 SV=1 CANONICAL=A0A8V0ZK51-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZK51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51/entry#A0A8V0ZK51-1", "sequence": { "sequence": "MQDDSLESSTSISQLLRESYLAETKHQGNSERSRSEPTSHNFLYGNSSGDSDEVVAQDDLPDLSAFLSQEELNESVNLARQAIDQNPLEAKQDELHPPDQLKNTGKKKQMAHSTALRTSDNGLPANFCQDRATDAKGSKGSPQDLKKHLPSESESKKEFLNKAADFIEELSSLFKAHNSERIRPRTCKNYRSKIDSKSKSAQKASSSLSGTSENRERLSIPLPLDLENKSEEAFEKLDDQLTEHSESINQLTSAELKTESESAYSDEPLGQPPRFTQKLKSREVPEGTKVQLDCIVVGIPTPEVRWYCEGKELENSPDIQIIQTGDQHSLVIVEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGASSSDSEGETKDEMEHNLKPADTSLKVAPPATRAATKPQETCKAPSAAVQPVSVPIQSVPTPVNQAESPTNYLQGLDGRPIVAAPVFTKMLQDISASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFSEDSGSFTCTASNKYGTVSSIAQLSVKASEDSNNAAALHTMSSINSVAAENQSPPHNPSQRVGSENPKPKLEGVLVNHNEPRSSSKIGLRVHFKLPEDDKGSESPPEDGLGTTNKTRPSYFHDKINGQPVKIPEPTSPSKEPPPVLAKPKLDLTQLKQLHNQVLLEQQQVHQTSSRDLSFNTTLLNSATSLNQQSTSTTYKQSKASVSQAFSYTRPKQFLPPQTTPPIISSSSSSVTIFSSVSQGIQRTNSRENVTGNPPPVQSRSSGGFTGKSEQSSPSPKESTVPLTLSTSSVKQFQPQSVTPAPVSPTGWIQNPVAFLSAVLPSLPSPPSTNAMGLPRSTPVTSTPGVTKKNPKPLQLPTDESIRENKAALVKDLERKLHFREDINQQSSQQEYRISSFEQRLMNEIEFRLERTPVDESDDEIQHEEIPTGKYIAPIFDKRLKHFRVMEGSPTTFTCKIVGIPVPKIYWFKDGKQISKKNTHYKMSREEDGTCSLHIEAATNDDDGNYTIMAANPQGRVSCSGHLMVQSIPVRGRLSTLQPHRARPRVPEGGDKEAVQERFFRPYFLQAPGDMVAHEGRLCRLDCKVSGLPTPDLTWLLNGKPVLPDGTHKMLVRETGVHSLLIDPLSQNDAGTYTCLATNKTGQNSFSLELTVVAKEVKKAPMFLEKLQNCGVPEGYPVRLECRVVGMPPPVFYWKKDNETIPSNRERMSMHQDTTGYVCLLIQPARKADAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPQQIKLRPGSSRYANLTGQGLDIYSGFPTTESPVLFSSPTQKMVESDEL", "length": 1334, "header": "tr|A0A8V0ZK51-1|A0A8V0ZK51_CHICK Isoform 1 of Myopalladin OS=Gallus gallus OX=9031 GN=MYPN PE=3 SV=1 CANONICAL=A0A8V0ZK51-1" }, "locus": { "chromosome": "6", "start_pos": 11293183, "end_pos": 11250886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055710.1", "url": "https://www.ensembl.org/id/ENSGALT00010055710.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033739.1", "url": "https://www.ensembl.org/id/ENSGALP00010033739.1" } ] } }, { "isoform_ac": "A0A8V0ZT94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51/entry#A0A8V0ZT94-1", "sequence": { "sequence": "MQDDSLESSTSISQLLRESYLAETKHQGNSERSRSEPTSHNFLYGNSSGDSDEVVAQDDLPDLSAFLSQEELNESVNLARQAIDQNPLEAKQDELHPPDQLKNTGKKKQMAHSTALRTSDNGLPANFCQDRATDAKGSKGSPQDLKKHLPSESESKKEFLNKAADFIEELSSLFKAHNSERIRPRTCKNYRSKIDSKSKSAQKASSSLSGTSENRERLSIPLPLDLENKSEEAFEKLDDQLTEHSESINQLTSAELKTESESAYSDEPLGQPPRFTQKLKSREVPEGTKVQLDCIVVGIPTPEVRWYCEGKELENSPDIQIIQTGDQHSLVIVEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGASSSDSEGETKDEMEHNLKPADTSLKVAPPATRAATKPQETCKAPSAAVQPVSVPIQSVPTPVNQAESPTNYLQGLDGRPIVAAPVFTKMLQDISASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFSEDSGSFTCTASNKYGTVSSIAQLSVKASEDSNNAAALHTMSSINSVAAENQSPPHNPSQRVGSENPKPKLEGVLVNHNEPRSSSKIGLRVHFKLPEDDKGSESPPEDGLGTTNKTRPSYFHDKINGQPVKIPEPTSPSKEPPPVLAKPKLDLTQLKQLHNQVLLEQQQVHQTSSRDLSFNTTLLNSATSLNQQSTSTTYKQSKASVSQAFSYTRPKQFLPPQTTPPIISSSSSSVTIFSSVSQGIQRTNSRENVTGNPPPVQSRSSGGFTGKSEQSSPSPKESTVPLTLSTSSVKQFQPQSVTPAPVSPTGWIQNPVAFLSAVLPSLPSPPSTNAMGLPRSTPVTSTPGVTKKNPKPLQLPTDESIRENKAALVKDLERKLHFREDINQQSSQQEYRISSFEQRLMNEIEFRLERTPVDESDDEIQHEEIPTGKYIAPIFDKRLKHFRVMEGSPTTFTCKIVGIPVPKIYWFKDGKQISKKNTHYKMSREEDGTCSLHIEAATNDDDGNYTIMAANPQGRVSCSGHLMVQSIPVRGRLSTLQPHRARPRVPEGGDKEAVQERFFRPYFLQAPGDMVAHEGRLCRLDCKVSGLPTPDLTWLLNGKPVLPDGTHKMLVRETGVHSLLIDPLSQNDAGTYTCLATNKTGQNSFSLELTVVAKEVKKAPMFLEKLQNCGVPEGYPVRLECRVVGMPPPVFYWKKDNETIPSNRERMSMHQDTTGYVCLLIQPARKADAGWYTLSAKNEAGIVSCTARLDIYVLPWIRHYSITA", "length": 1290, "header": "tr|A0A8V0ZT94-1|A0A8V0ZK51_CHICK Computationally mapped isoform of Myopalladin OS=Gallus gallus OX=9031 GN=MYPN PE=3 SV=1 CANONICAL=A0A8V0ZK51-1" }, "locus": { "chromosome": "6", "start_pos": 11291819, "end_pos": 11250886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055701.1", "url": "https://www.ensembl.org/id/ENSGALT00010055701.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033732.1", "url": "https://www.ensembl.org/id/ENSGALP00010033732.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 824, "start_aa": "Thr", "end_pos": 824, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr824", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 868, "start_aa": "Thr", "end_pos": 868, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr868", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K046-1", "protein_name": "Myopalladin", "gene_name": "Mypn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQDDSIEASTSISQLLRESYLAETRHRGDNERSRAEPSSNPFHFSSPGAAEGGGPEDLPDLSAFLSQEELDESVNLARLAINHDPLERVDESQTRKRLSSDQKPSFEPAFLQDSSRGLASSKDSPPETKRPQYSSETQSKKVFLNKAADFIEELSSLFKAHSSKRIRPRACKNHKSKTESPNKVVQENSPTFSDLTERRERTSVPIPIPADSRDNELNHAIEQREAKRREAELAAVEAAAGDSTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGSRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSATIPPTVQAQPRVSTIQQCQSPTNYLQGLNGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLAVRGNEDISDNETLHSDNSTTNPAATEQQPSPPNPQPPPEEQPPKPKLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKDTEASSGCGMANTSQTRPDSFPERFNGQEARISEPSSPVKEPPPVLAKPKLDSTQLQQLHNQVLLEQLQLHNTSPSSPKESPFNTSILNSAPPTVTISSKQVKSPAPQTFNLARPKHFFPASSTSTATVSPSSSPVFTLSNTPQTIQRTVSKESLLMTHPSTQGRSPGGLSIQNEPAPPSPAEPAVPTVSYSITSGNQFQPHCVSPTPVSPTGRIQNPVAFLSSVLPSLPSIPPTNAMGLPKSAPSVPPQGLMKKTTKTPQAVSDDYIRETKNSVILDLGKKVNFSDVRSHQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRRDGDGTCSLHIESTHGDDDGNYTIMAANPQGRISCSGHLMVQGFPIRNRLSPAGQSHRGRSRMQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYTCVATNKTGQNSFSLELTVVAKEVKKAPVILEKLQNSGVPEGHPVRLEGRVIGMPPPVFYWKKDNETIPFTRERISMHQDTTGYVCLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHQQIPTPISIRPSGSRYGSLTSKGLDIFSAFSSMESTMMYSCTSRSVVESDEL", "length": 1306 }, "evidence": [ { "id": "A0A8V0ZK51", "url": "https://omabrowser.org/oma/group/A0A8V0ZK51/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HAA5-1", "protein_name": "Myopalladin", "gene_name": "Mypn", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQDDSIEASTSISQLLRESYLAETRHRGDNERSRAEPSSNPFHFGSPSGAAEGGGQEDLPDLSAFLSQEELDESVNLARLAINHDPLERVDEAQARKRLSSDKTKLSPKPSFEPAFCQDSPGGPASSKDSPPETKRPQYSSETQSKKVFLNKAADFIEELSSLFKAHSSKRIRPRACKNHKSKTESQNKALQKNSSTFSDLTERRERASVPIPIPADSRDNELNHAIEQREAKRREAELAAGEAAAGDSTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGSRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNELSSPPTTSAAIPPVAQGQPQVSTIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFSEDSGCFTCTASNKYGTVSSIAQLDVRGNEDISNNGTLHSANSATNLAVAEQQPSPPNPEPRPEEQPPKPKLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKESDASSGCGVANTSQTRPDSFPERFNGQEARTPEPSSPVKEPPPVLAKPKLDSTQLQQLHNQVLLEQQQLQTPSSPKEAPFNFGVLNSAPPAVTISSKQVKGSAPQTFNLARPKHFFPASSSSAAAVSPSSSPVFTLSNAPSTIQRTVSKESLLLSHPSAHGRSPGGLSIQNEPAPPGPAELAVPPPLPYPVPSGNQFQPHCVSPTPVSPTGRIQNPVAFLSSVLPSLPSIPPTNAMGLPKSAPSAPPQGLMKKTTKAPQTMSDDYIRETKNSVILDLGKKVNFSDVRSHQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTNSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRNRLSPAGQSHRGRSRMQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYTCVATNKTGQNSFSLELTVVAKEVKKAPMILEKLQNSGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPFTRERISMHQDTTGYVCLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPPPMSIRPSGSRYGSLTSKGLDIFSAFSSVESTMVYSCTSRSVVESDEL", "length": 1311 }, "evidence": [ { "id": "A0A8V0ZK51", "url": "https://omabrowser.org/oma/group/A0A8V0ZK51/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5DTJ9-1", "protein_name": "Myopalladin", "gene_name": "Mypn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQEDSIEASTSISQLLRESYLAETRHRGDNERSRAEPSSNPFHFSGPGAAEGGGPEDLPDLSAFLSQEELDESVNLARLAINHDPLERVDEAQARKRLSSDQTKHASKPSFEPAFHQDSSRGPASPKDSPPETKRPQYSSETQSKKVFLNKAADFIEELSSLFKAHSSKRIRPRACKNHKSKTESQNKVLQENSPTFSDLTERRERASVPIPIPADSRDNELNHAIEQREAKRREAELAAGEAAAGDSTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGSRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAAIPPAAEAQPLAAQPRVSTVQQCQSPTNYLQGLNGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFSEDSGCFTCTASNKYGTVSSIAQLDVRGNEDISDNGALHSANSTTNPAVAEHQPSPLNPQPLSEEQPPKPKLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKDMEASSGSGAANTSQTRPNSFPERFNGQEARIPEPSSPIKEPPPVLAKPKLDSTQLQQLHNQVLLEQQQLQNTSPSSPKESLHMSALNSAPPAVTISSKQVKGPAPQMFNLARPKHFFPASSTSTATVSPSSSPVFTLSNTPQTIQRTVSKESLLMAHPSTQGRSPGGLSIQNEPAPPSPAEPAAPPTAAYSIPSGNQFQPHCVSPTPVSPTGRIQNPVAFLSSVLPSLPSIPPTNAMGLPKSAPSVPSQGLMKKTTKAPQAVSDDYIRETKNSVILDLGKKVNFGDVRSHQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIEHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTHGDDDGNYTIMAANPQGRISCSGHLMVQGLPIRSRLSPALSHRGRSRMQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYTCVATNKTGQNSFSLELTVVAKEVKKAPVILEKLQNSGVPEGHPVRLEGRVIGMPPPVFYWKKDNETIPFTRERISMHQDTTGYVCLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHQQIPTPISIRPSGSRYGSLTSKGLDIFSAFSSVESTMLYSCTSRSVVESDEL", "length": 1315 }, "evidence": [ { "id": "A0A8V0ZK51", "url": "https://omabrowser.org/oma/group/A0A8V0ZK51/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86TC9-1", "protein_name": "Myopalladin", "gene_name": "MYPN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQDDSIEASTSISQLLRESYLAETRHRGNNERSRAEPSSNPCHFGSPSGAAEGGGGQDDLPDLSAFLSQEELDESVNLARLAINYDPLEKADETQARKRLSPDQMKHSPNLSFEPNFCQDNPRSPTSSKESPQEAKRPQYCSETQSKKVFLNKAADFIEELSSLFKSHSSKRIRPRACKNHKSKLESQNKVMQENSSSFSDLSERRERSSVPIPIPADTRDNEVNHALEQQEAKRREAEQAASEAAGGDTTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTNLAAIEPQPSPPHSEPPSVEQPPKPKLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKGSEASSEAGVVTTRQTRPDSFQERFNGQATKTPEPSSPVKEPPPVLAKPKLDSTQLQQLHNQVLLEQHQLQNPPPSSPKEFPFSMTVLNSNAPPAVTTSSKQVKAPSSQTFSLARPKYFFPSTNTTAATVAPSSSPVFTLSSTPQTIQRTVSKESLLVSHPSVQTKSPGGLSIQNEPLPPGPTEPTPPPFTFSIPSGNQFQPRCVSPIPVSPTSRIQNPVAFLSSVLPSLPAIPPTNAMGLPRSAPSMPSQGLAKKNTKSPQPVNDDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPPPMSVRPSGSRYGSLTSKGLDIFSAFSSMESTMVYSCSSRSVVESDEL", "length": 1320 }, "evidence": [ { "id": "A0A8V0ZK51", "url": "https://omabrowser.org/oma/group/A0A8V0ZK51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "muscle alpha-actinin binding", "id": "GO:0051371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051371", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1030, "end_pos": 1032, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1164, "end_pos": 1166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1223, "end_pos": 1225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1300, "end_pos": 1302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 701, "end_pos": 703, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 774, "end_pos": 776, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK51" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 273, "end_pos": 363, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 824, 868 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1030, "end_pos": 1032 }, { "start_pos": 1164, "end_pos": 1166 }, { "start_pos": 1223, "end_pos": 1225 }, { "start_pos": 1300, "end_pos": 1302 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 46, "end_pos": 48 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 634, "end_pos": 636 }, { "start_pos": 701, "end_pos": 703 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 774, "end_pos": 776 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZK85-1", "uniprot_ac": "A0A8V0ZK85", "uniprot_id": "A0A8V0ZK85_CHICK", "mass": { "chemical_mass": 27039.0, "monoisotopic_mass": 27039.0 }, "refseq": { "ac": "XP_415263", "name": "protein unc-119 homolog B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415263" }, "gene_names": [ { "name": "UNC119B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" } ] }, { "name": "UNC119B", "type": "synonym", "evidence": [ { "id": "XP_415263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415263" } ] } ], "protein_names": [ { "name": "Unc-119 lipid binding chaperone B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZK85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85/entry#names_and_taxonomy" } ] }, { "name": "protein unc-119 homolog B", "type": "synonym", "evidence": [ { "id": "XP_415263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415263" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_415263.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415263" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UNC119B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85", "locus": { "chromosome": "15", "start_pos": 9190790, "end_pos": 9196984, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022933", "url": "https://www.ensembl.org/id/ENSGALG00010022933" } ] } } ], "crossref": [ { "id": "A0A8V0ZK85", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZK85", "database": "AlphaFoldDB", "categories": [] }, { "id": "416970", "url": "https://www.ncbi.nlm.nih.gov/gene/416970", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416970", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416970", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYLCRPE", "url": "https://omabrowser.org/oma/group/HYLCRPE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK85", "url": "https://www.orthodb.org/?gene=A0A8V0ZK85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12951", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12951", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12951:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12951:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05351", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05351", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5624138", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624138", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_415263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415263", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGSRARAAAGPDKKPPPGSGGALSRLRGRRGSADAAPRPGAPWTESELLELETVRPEHVLGLCRVTENYLCKPEDNIYNIDFTRFKIRDLETGTVLFEIAKPSAAEQDNEDEDDSGELDSSAGRFVRYQFTPAFLRLRTVGATVEFTVGEKPVSNFRMIERHYFRDRLLKNFDFDFGFCIPSSRNTCEHIYEFPQLSEDLIRLMVENPYETRSDSFYFVDNKLIMHNKADYAYNGGQ", "length": 238, "header": "tr|A0A8V0ZK85-1|A0A8V0ZK85_CHICK Isoform 1 of Unc-119 lipid binding chaperone B OS=Gallus gallus OX=9031 GN=UNC119B PE=1 SV=1 CANONICAL=A0A8V0ZK85-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZK85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85/entry#A0A8V0ZK85-1", "sequence": { "sequence": "MSGSRARAAAGPDKKPPPGSGGALSRLRGRRGSADAAPRPGAPWTESELLELETVRPEHVLGLCRVTENYLCKPEDNIYNIDFTRFKIRDLETGTVLFEIAKPSAAEQDNEDEDDSGELDSSAGRFVRYQFTPAFLRLRTVGATVEFTVGEKPVSNFRMIERHYFRDRLLKNFDFDFGFCIPSSRNTCEHIYEFPQLSEDLIRLMVENPYETRSDSFYFVDNKLIMHNKADYAYNGGQ", "length": 238, "header": "tr|A0A8V0ZK85-1|A0A8V0ZK85_CHICK Isoform 1 of Unc-119 lipid binding chaperone B OS=Gallus gallus OX=9031 GN=UNC119B PE=1 SV=1 CANONICAL=A0A8V0ZK85-1" }, "locus": { "chromosome": "15", "start_pos": 9196952, "end_pos": 9194292, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055797.1", "url": "https://www.ensembl.org/id/ENSGALT00010055797.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033778.1", "url": "https://www.ensembl.org/id/ENSGALP00010033778.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416970", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416970", "resource": "KEGG Pathway" }, { "id": "R-GGA-5624138", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5624138", "resource": "Reactome", "description": "Trafficking of myristoylated proteins to the cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "Q90Z08-1", "protein_name": "Protein unc-119 homolog B", "gene_name": "unc119b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSQSSRNETAATAVNGSDSAAASRDHKSGGGVLKRLKSRRNQVDRRPVTEEELRALGRDITPDEVLGLRAVARDYLCKLEDNIYNIDFTRFKIRDLETGTVLFEIAKPPHCDLDEEDDENRDADTSAGRFVRYQFTPAFLKLRTVGATVEFTVGDQPVTNFRMIERHYFQDRLLKSFDFDFGFCIPNSRNTCEHIYEFPQLPEDLIRLMIEHPYETRSDSFYFVDNKLIMHNKADYAYNGGQ", "length": 243 }, "evidence": [ { "id": "A0A8V0ZK85", "url": "https://omabrowser.org/oma/group/A0A8V0ZK85/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "sperm end piece", "id": "GO:0097229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" } ], "pmid": "" }, { "name": "sperm principal piece", "id": "GO:0097228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" } ], "pmid": "" }, { "name": "lipoprotein transport", "id": "GO:0042953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZK85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK85" }, { "id": "PF05351", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05351" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GMP phosphodiesterase delta subunit", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 234, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLX0-1", "uniprot_ac": "A0A8V0ZLX0", "uniprot_id": "A0A8V0ZLX0_CHICK", "mass": { "chemical_mass": 30204.0, "monoisotopic_mass": 30204.0 }, "refseq": {}, "gene_names": [ { "name": "NIFK", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0" } ] } ], "protein_names": [ { "name": "Nucleolar protein interacting with the FHA domain of MKI67", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NIFK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0", "locus": { "chromosome": "7", "start_pos": 25855155, "end_pos": 25865358, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021759", "url": "https://www.ensembl.org/id/ENSGALG00010021759" } ] } } ], "crossref": [ { "id": "A0A8V0ZLX0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12307", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12307", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK86", "url": "https://www.orthodb.org/?gene=A0A8V0ZK86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLX0", "url": "https://www.orthodb.org/?gene=A0A8V0ZLX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46754", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46754", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12196", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12196", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZK86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAAGAGVPASFLSLEPQLQSTVQKKVRRARKNRVAEEELTPGVVYVGHLPRGLCEPQLRQYFEQFGTVRRLRLSRSKKTGGSKGYAFIEFESDDVAKIVADTMNNYLFSERLLKCQFMPPERVHANLFKNSERMFQKPSQPAVKRYNKVRSLVEKAKMAKRLLRKENCLRKRLAEKGIKYSFPGFAAQGLPVKRKKVKRSKAKQNVSLTSQRPEGCQEEHGHVHCNTTMRHIAYGCPRPDTIRLPGCCIQSISGQKELEAPAFQ", "length": 267, "header": "tr|A0A8V0ZLX0-1|A0A8V0ZLX0_CHICK Isoform 1 of Nucleolar protein interacting with the FHA domain of MKI67 OS=Gallus gallus OX=9031 GN=NIFK PE=1 SV=1 CANONICAL=A0A8V0ZLX0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZK86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0/entry#A0A8V0ZK86-1", "sequence": { "sequence": "MAAAAAGAGVPASFLSLEPQLQSTVQKKEELTPGVVYVGHLPRGLCEPQLRQYFEQFGTVRRLRLSRSKKTGGSKGYAFIEFESDDVAKIVADTMNNYLFSERLLKCQFMPPERVHANLFKNSERMFQKPSQPAVKRYNKVRSLVEKAKMAKRLLRKENCLRKRLAEKGIKYSFPGFAAQGLPVKRKKVKRSKAKQNVSLTSQDPTPVCTPTVLERRKAQQADDDPDDNEIIIKLPPPSVKKAVQRPKKQPRKKKQPEETKAGLKF", "length": 266, "header": "tr|A0A8V0ZK86-1|A0A8V0ZLX0_CHICK Computationally mapped isoform of Nucleolar protein interacting with the FHA domain of MKI67 OS=Gallus gallus OX=9031 GN=NIFK PE=1 SV=1 CANONICAL=A0A8V0ZLX0-1" }, "locus": { "chromosome": "7", "start_pos": 25865316, "end_pos": 25862026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052898.1", "url": "https://www.ensembl.org/id/ENSGALT00010052898.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031804.1", "url": "https://www.ensembl.org/id/ENSGALP00010031804.1" } ] } }, { "isoform_ac": "A0A8V0ZLX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0/entry#A0A8V0ZLX0-1", "sequence": { "sequence": "MAAAAAGAGVPASFLSLEPQLQSTVQKKVRRARKNRVAEEELTPGVVYVGHLPRGLCEPQLRQYFEQFGTVRRLRLSRSKKTGGSKGYAFIEFESDDVAKIVADTMNNYLFSERLLKCQFMPPERVHANLFKNSERMFQKPSQPAVKRYNKVRSLVEKAKMAKRLLRKENCLRKRLAEKGIKYSFPGFAAQGLPVKRKKVKRSKAKQNVSLTSQRPEGCQEEHGHVHCNTTMRHIAYGCPRPDTIRLPGCCIQSISGQKELEAPAFQ", "length": 267, "header": "tr|A0A8V0ZLX0-1|A0A8V0ZLX0_CHICK Isoform 1 of Nucleolar protein interacting with the FHA domain of MKI67 OS=Gallus gallus OX=9031 GN=NIFK PE=1 SV=1 CANONICAL=A0A8V0ZLX0-1" }, "locus": { "chromosome": "7", "start_pos": 25865316, "end_pos": 25856568, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052900.1", "url": "https://www.ensembl.org/id/ENSGALT00010052900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031806.1", "url": "https://www.ensembl.org/id/ENSGALP00010031806.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0" } ], "pmid": "" }, { "name": "condensed nuclear chromosome", "id": "GO:0000794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLX0" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 123, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 }, { "start_pos": 229, "end_pos": 231 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZK92-1", "uniprot_ac": "A0A8V0ZK92", "uniprot_id": "A0A8V0ZK92_CHICK", "mass": { "chemical_mass": 67938.0, "monoisotopic_mass": 67938.0 }, "refseq": {}, "gene_names": [ { "name": "MTF2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92" } ] } ], "protein_names": [ { "name": "Metal-response element-binding transcription factor 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZK92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92/entry#names_and_taxonomy" } ] }, { "name": "Metal regulatory transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZK92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity. Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation. Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells. Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex. In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally. Binds to the metal-regulating-element (MRE) of MT1A gene promoter.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92#function" }, { "database": "UniProtKB", "id": "ARBA00058935", "url": "https://www.uniprot.org/uniprotkb/ARBA00058935#function" }, { "database": "UniProtKB", "id": "A0A8V0ZSK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MTF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92", "locus": { "chromosome": "8", "start_pos": 13724937, "end_pos": 13751838, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021753", "url": "https://www.ensembl.org/id/ENSGALG00010021753" } ] } } ], "crossref": [ { "id": "A0A8V0ZK92", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZK92", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15578", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15578", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15580", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15580", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK92", "url": "https://www.orthodb.org/?gene=A0A8V0ZK92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSK9", "url": "https://www.orthodb.org/?gene=A0A8V0ZSK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12628:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12628:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-212300", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212300", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZK92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRDSTAVGNSLVHKRSPLRRSHKASASSPKLSLRDGQKAKKPLCKFEEGQDVLARWSDGLFYLGTIKKINKLKQNCFIIFEDSSKSWVLWKDIQTGKNFRATESGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPNIDSSVIDSDDKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYNATDLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLRWVDIAHLCLYNLSVIHKKKYFDSELELMAYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNAALKAEKEPEGTSHEFKIKGRKSSKPIPDVRELSNGIERKGKKKSVGRPPGPYTRKMIHKTPESSPLDTEPVPVIETPALELPCSVGKSDGTAHSSNTSDVESTGAASIKETTSSSISRHYSSLSDSRKRTRTGRTWPAAIPHLRRRGRFPRKALQTQNSEIVKDDESKEDYQYDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 600, "header": "tr|A0A8V0ZK92-1|A0A8V0ZK92_CHICK Isoform 1 of Metal-response element-binding transcription factor 2 OS=Gallus gallus OX=9031 GN=MTF2 PE=3 SV=1 CANONICAL=A0A8V0ZK92-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZK92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92/entry#A0A8V0ZK92-1", "sequence": { "sequence": "MRDSTAVGNSLVHKRSPLRRSHKASASSPKLSLRDGQKAKKPLCKFEEGQDVLARWSDGLFYLGTIKKINKLKQNCFIIFEDSSKSWVLWKDIQTGKNFRATESGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPNIDSSVIDSDDKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYNATDLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLRWVDIAHLCLYNLSVIHKKKYFDSELELMAYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNAALKAEKEPEGTSHEFKIKGRKSSKPIPDVRELSNGIERKGKKKSVGRPPGPYTRKMIHKTPESSPLDTEPVPVIETPALELPCSVGKSDGTAHSSNTSDVESTGAASIKETTSSSISRHYSSLSDSRKRTRTGRTWPAAIPHLRRRGRFPRKALQTQNSEIVKDDESKEDYQYDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 600, "header": "tr|A0A8V0ZK92-1|A0A8V0ZK92_CHICK Isoform 1 of Metal-response element-binding transcription factor 2 OS=Gallus gallus OX=9031 GN=MTF2 PE=3 SV=1 CANONICAL=A0A8V0ZK92-1" }, "locus": { "chromosome": "8", "start_pos": 13751620, "end_pos": 13729120, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052904.1", "url": "https://www.ensembl.org/id/ENSGALT00010052904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031810.1", "url": "https://www.ensembl.org/id/ENSGALP00010031810.1" } ] } }, { "isoform_ac": "A0A8V0ZSK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92/entry#A0A8V0ZSK9-1", "sequence": { "sequence": "FRDSTAVGNSLVHKRSPLRRSHKASASSPKLSLRDGQKAKKPLCKFEEGQDVLARWSDGLFYLGTIKKINKLKQNCFIIFEDSSKSWVLWKDIQTGATESGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPNIDSSVIDSDDKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYNATDLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLRWVDIAHLCLYNLSVIHKKKYFDSELELMAYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNAALKAEKEPEGTSHEFKIKGRKSSKPIPDVRELSNGIERKGKKKSVGRPPGPYTRKMIHKTPESSPLDTEPVPVIETPALELPCSVGKSDGTAHSSNTSDVESTGAASIKETTSSSISRHYSLSDSRKRTRTGRTWPAAIPHLRRRGRFPRKALQTQNSEIVKDDESKEDYQYDELNTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 595, "header": "tr|A0A8V0ZSK9-1|A0A8V0ZK92_CHICK Computationally mapped isoform of Metal-response element-binding transcription factor 2 OS=Gallus gallus OX=9031 GN=MTF2 PE=3 SV=1 CANONICAL=A0A8V0ZK92-1" }, "locus": { "chromosome": "8", "start_pos": 13741803, "end_pos": 13729120, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052882.1", "url": "https://www.ensembl.org/id/ENSGALT00010052882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031788.1", "url": "https://www.ensembl.org/id/ENSGALP00010031788.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-212300", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-212300", "resource": "Reactome", "description": "PRC2 methylates histones and DNA" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": 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"transcription corepressor binding", "id": "GO:0001222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92" } ], "pmid": "" }, { "name": "histone H3K36me3 reader activity", "id": "GO:0140003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK92" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK92", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZKG5" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG5" } ], "pmid": "" }, { "name": "positive regulation of protein export from nucleus", "id": "GO:0046827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046827", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG5" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG5" } ], "pmid": "" }, { "name": "positive regulation of muscle cell differentiation", "id": "GO:0051149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG5" } ], "pmid": "" }, { "name": "positive regulation of dendritic spine development", "id": "GO:0060999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060999", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG5" } ], "pmid": "" }, { "name": "regulation of synapse organization", "id": "GO:0050807", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050807", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG5" } ], "pmid": "" }, { "name": "positive regulation of synapse structural plasticity", "id": "GO:0051835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051835", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG5" } ], "pmid": "" }, { "name": "positive regulation of syncytium formation by plasma membrane fusion", "id": "GO:0060143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060143", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG5" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 280, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 312, "end_pos": 314 }, { "start_pos": 362, "end_pos": 364 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKE6-1", "uniprot_ac": "A0A8V0ZKE6", "uniprot_id": "A0A8V0ZKE6_CHICK", "mass": { "chemical_mass": 76809.0, "monoisotopic_mass": 76809.0 }, "refseq": { "ac": "XP_419458", "name": "ATP-binding cassette sub-family G member 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419458" }, "gene_names": [ { "name": "ABCG8", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ] }, { "name": "ABCG8", "type": "synonym", "evidence": [ { "id": "XP_419458", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419458" } ] } ], "protein_names": [ { "name": "ATP-binding cassette sub-family G member 8", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6/entry#names_and_taxonomy" } ] }, { "name": "ATP-binding cassette sub-family G member 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_419458", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419458" } ] }, { "name": "Sterolin-2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_419458.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419458" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABCG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6", "locus": { "chromosome": "3", "start_pos": 24938405, "end_pos": 24924617, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020360", "url": "https://www.ensembl.org/id/ENSGALG00010020360" } ] } } ], "crossref": [ { "id": "A0A8V0ZKE6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKE6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421402", "url": "https://www.ncbi.nlm.nih.gov/gene/421402", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WLAWEDY", "url": "https://omabrowser.org/oma/group/WLAWEDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKE6", "url": "https://www.orthodb.org/?gene=A0A8V0ZKE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48041", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48041", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48041:SF71", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48041:SF71", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1369062", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1369062", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_419458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419458", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKDPENISLEGASWSQDRCTSLSAQDSIFCSEEDNSLYFTYSGKSNVLEVKELNYQVNLASQIPWYEKLTQMQLLLPWNSGPDSHVSIIQNLNLKVHSGQMLAIIGSTAGGKTSLLDVITCRDHGGKIKSGHIMINNKPSTPQLVKKCIAHVRQDDRLLPHLTVRETLLFIARLRLPACFSDSQRQKRVEDVIAELRLRQCANTRVGNEYLRGISGGERRRVSIAVQLLWNPGILILDEPTSGLDSFTSHNLVITLSRLARGNRLVLLSLHQPRSDIFQLFDLVLLMTSGVTIYSGAARDMVQYFTELGYPCPRYSNPADFYVDLTSIDKQTTEKEMESLKRANTLASLFQEKIKDYDDFLWKASEGDSVVTTTSKQSSHSKPEEVINMPYHSSDQLPGVLKQFTVLLSRQVSNDFRDISTLLVHGFEALVMSLLIGFLYYGHEGRLSIRDTSALLYMIGALIPFTVILDVIAKCHSERAMLYLDLENGMYSVTPYFFAKILGELPEHCAFVIIYGVPIYWLTNLFPEAEHFLLNFFSVWLAVYCARAMALWVAALLPTLQLSAFLGNVLFTSFYLSGGFVISLEQLWTVPYWVSKVSFLRWNFQGMMQIQFTDSIYDMPFGNVTIKIPGKLVTKALGLDSEPLYISYLIIGGNIFCFLLLYYLSLRFIKQKSNQDW", "length": 678, "header": "tr|A0A8V0ZKE6-1|A0A8V0ZKE6_CHICK Isoform 1 of ATP-binding cassette sub-family G member 8 OS=Gallus gallus OX=9031 GN=ABCG8 PE=3 SV=1 CANONICAL=A0A8V0ZKE6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6/entry#A0A8V0ZKE6-1", "sequence": { "sequence": "MKKDPENISLEGASWSQDRCTSLSAQDSIFCSEEDNSLYFTYSGKSNVLEVKELNYQVNLASQIPWYEKLTQMQLLLPWNSGPDSHVSIIQNLNLKVHSGQMLAIIGSTAGGKTSLLDVITCRDHGGKIKSGHIMINNKPSTPQLVKKCIAHVRQDDRLLPHLTVRETLLFIARLRLPACFSDSQRQKRVEDVIAELRLRQCANTRVGNEYLRGISGGERRRVSIAVQLLWNPGILILDEPTSGLDSFTSHNLVITLSRLARGNRLVLLSLHQPRSDIFQLFDLVLLMTSGVTIYSGAARDMVQYFTELGYPCPRYSNPADFYVDLTSIDKQTTEKEMESLKRANTLASLFQEKIKDYDDFLWKASEGDSVVTTTSKQSSHSKPEEVINMPYHSSDQLPGVLKQFTVLLSRQVSNDFRDISTLLVHGFEALVMSLLIGFLYYGHEGRLSIRDTSALLYMIGALIPFTVILDVIAKCHSERAMLYLDLENGMYSVTPYFFAKILGELPEHCAFVIIYGVPIYWLTNLFPEAEHFLLNFFSVWLAVYCARAMALWVAALLPTLQLSAFLGNVLFTSFYLSGGFVISLEQLWTVPYWVSKVSFLRWNFQGMMQIQFTDSIYDMPFGNVTIKIPGKLVTKALGLDSEPLYISYLIIGGNIFCFLLLYYLSLRFIKQKSNQDW", "length": 678, "header": "tr|A0A8V0ZKE6-1|A0A8V0ZKE6_CHICK Isoform 1 of ATP-binding cassette sub-family G member 8 OS=Gallus gallus OX=9031 GN=ABCG8 PE=3 SV=1 CANONICAL=A0A8V0ZKE6-1" }, "locus": { "chromosome": "3", "start_pos": 24936654, "end_pos": 24924741, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049180.1", "url": "https://www.ensembl.org/id/ENSGALT00010049180.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029076.1", "url": "https://www.ensembl.org/id/ENSGALP00010029076.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1369062", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1369062", "resource": "Reactome", "description": "ABC transporters in lipid homeostasis" } ], "orthologs": [ { "uniprot_canonical_ac": "P58428-3", "protein_name": "ATP-binding cassette sub-family G member 8", "gene_name": "Abcg8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEKTKEETQLWNGTVLQDASSLQDSVFSSESDNSLYFTYSGQSNTLEVRDLTYQGGTCLRSWGQEDPHMSLGLSESVDMASQVPWFEQLAQFKLPWRSRGSQDSWDLGIRNLSFKVRSGQMLAIIGSAGCGRATLLDVITGRDHGGKMKSGQIWINGQPSTPQLIQKCVAHVRQQDQLLPNLTVRETLTFIAQMRLPKTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVRTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGVAQHMVQYFTSIGYPCPRYSNPADFYVDLTSIDRRSKEQEVATMEKARLLAALFLEKVQGFDDFLWKAEAKSLDTGTYAVSQTLTQDTNCGTAAELPGMIQQFTTLIRRQISNDFRDLPTLFIHGAEACLMSLIIGFLYYGHADKPLSFMDMAALLFMIGALIPFNVILDVVSKCHSERSLLYYELEDGLYTAGPYFFAKVLGELPEHCAYVIIYGMPIYWLTNLRPGPELFLLHFMLLWLVVFCCRTMALAASAMLPTFHMSSFCCNALYNSFYLTAGFMINLNNLWIVPAWISKMSFLRWCFSGLMQIQFNGHIYTTQIGNLTFSVPGDAMVTAMDLNSHPLYAIYLIVIGISCGFLSLYYLSLKFIKQKSIQDW", "length": 694 }, "evidence": [ { "id": "A0A8V0ZKE6", "url": "https://omabrowser.org/oma/group/A0A8V0ZKE6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q93YS4-1", "protein_name": "ABC transporter G family member 22", "gene_name": "ABCG22", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMEKPPLASGLARTRSEQLYETVAADIRSPHGSMDANGVPATAPAAVGGGGTLSRKSSRRLMGMSPGRSSGAGTHIRKSRSAQLKLELEEVSSGAALSRASSASLGLSFSFTGFAMPPEEISDSKPFSDDEMIPEDIEAGKKKPKFQAEPTLPIFLKFRDVTYKVVIKKLTSSVEKEILTGISGSVNPGEVLALMGPSGSGKTTLLSLLAGRISQSSTGGSVTYNDKPYSKYLKSKIGFVTQDDVLFPHLTVKETLTYAARLRLPKTLTREQKKQRALDVIQELGLERCQDTMIGGAFVRGVSGGERKRVSIGNEIIINPSLLLLDEPTSGLDSTTALRTILMLHDIAEAGKTVITTIHQPSSRLFHRFDKLILLGRGSLLYFGKSSEALDYFSSIGCSPLIAMNPAEFLLDLANGNINDISVPSELDDRVQVGNSGRETQTGKPSPAAVHEYLVEAYETRVAEQEKKKLLDPVPLDEEAKAKSTRLKRQWGTCWWEQYCILFCRGLKERRHEYFSWLRVTQVLSTAVILGLLWWQSDIRTPMGLQDQAGLLFFIAVFWGFFPVFTAIFAFPQERAMLNKERAADMYRLSAYFLARTTSDLPLDFILPSLFLLVVYFMTGLRISPYPFFLSMLTVFLCIIAAQGLGLAIGAILMDLKKATTLASVTVMTFMLAGGFFVKKVPVFISWIRYLSFNYHTYKLLLKVQYQDFAVSINGMRIDNGLTEVAALVVMIFGYRLLAYLSLRQMKIVT", "length": 751 }, "evidence": [ { "id": "A0A8V0ZKE6", "url": "https://omabrowser.org/oma/group/A0A8V0ZKE6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9DBM0-1", "protein_name": "ATP-binding cassette sub-family G member 8", "gene_name": "Abcg8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEKTKEETQLWNGTVLQDASQGLQDSLFSSESDNSLYFTYSGQSNTLEVRDLTYQVDIASQVPWFEQLAQFKIPWRSHSSQDSCELGIRNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKMKSGQIWINGQPSTPQLVRKCVAHVRQHDQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVTTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQQMVQYFTSIGHPCPRYSNPADFYVDLTSIDRRSKEREVATVEKAQSLAALFLEKVQGFDDFLWKAEAKELNTSTHTVSLTLTQDTDCGTAVELPGMIEQFSTLIRRQISNDFRDLPTLLIHGSEACLMSLIIGFLYYGHGAKQLSFMDTAALLFMIGALIPFNVILDVVSKCHSERSMLYYELEDGLYTAGPYFFAKILGELPEHCAYVIIYAMPIYWLTNLRPVPELFLLHFLLVWLVVFCCRTMALAASAMLPTFHMSSFFCNALYNSFYLTAGFMINLDNLWIVPAWISKLSFLRWCFSGLMQIQFNGHLYTTQIGNFTFSILGDTMISAMDLNSHPLYAIYLIVIGISYGFLFLYYLSLKLIKQKSIQDW", "length": 673 }, "evidence": [ { "id": "A0A8V0ZKE6", "url": "https://omabrowser.org/oma/group/A0A8V0ZKE6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H221-1", "protein_name": "ATP-binding cassette sub-family G member 8", "gene_name": "ABCG8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGKAAEERGLPKGATPQDTSGLQDRLFSSESDNSLYFTYSGQPNTLEVRDLNYQVDLASQVPWFEQLAQFKMPWTSPSCQNSCELGIQNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKIKSGQIWINGQPSSPQLVRKCVAHVRQHNQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCADTRVGNMYVRGLSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVKTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQHMVQYFTAIGYPCPRYSNPADFYVDLTSIDRRSREQELATREKAQSLAALFLEKVRDLDDFLWKAETKDLDEDTCVESSVTPLDTNCLPSPTKMPGAVQQFTTLIRRQISNDFRDLPTLLIHGAEACLMSMTIGFLYFGHGSIQLSFMDTAALLFMIGALIPFNVILDVISKCYSERAMLYYELEDGLYTTGPYFFAKILGELPEHCAYIIIYGMPTYWLANLRPGLQPFLLHFLLVWLVVFCCRIMALAAAALLPTFHMASFFSNALYNSFYLAGGFMINLSSLWTVPAWISKVSFLRWCFEGLMKIQFSRRTYKMPLGNLTIAVSGDKILSVMELDSYPLYAIYLIVIGLSGGFMVLYYVSLRFIKQKPSQDW", "length": 673 }, "evidence": [ { "id": "A0A8V0ZKE6", "url": "https://omabrowser.org/oma/group/A0A8V0ZKE6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "ATPase-coupled transmembrane transporter activity", "id": "GO:0042626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042626", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "cholesterol transfer activity", "id": "GO:0120020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "ATP-binding cassette (ABC) transporter complex", "id": "GO:0043190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043190", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "negative regulation of intestinal phytosterol absorption", "id": "GO:0010949", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010949", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "cholesterol efflux", "id": "GO:0033344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033344", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" }, { "name": "negative regulation of intestinal cholesterol absorption", "id": "GO:0045796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045796", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE6" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 73, "end_pos": 315, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 624, "end_pos": 626 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZME1-1", "uniprot_ac": "A0A8V0ZME1", "uniprot_id": "A0A8V0ZME1_CHICK", "mass": { "chemical_mass": 123440.0, "monoisotopic_mass": 123440.0 }, "refseq": {}, "gene_names": [ { "name": "RBL2", "type": "recommended", "evidence": [ { "id": 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"https://www.ensembl.org/id/ENSGALG00010021778" } ] } } ], "crossref": [ { "id": "A0A8V0ZME1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZME1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20606", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20606", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKF7", "url": "https://www.orthodb.org/?gene=A0A8V0ZKF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMD6", "url": "https://www.orthodb.org/?gene=A0A8V0ZMD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZME1", "url": "https://www.orthodb.org/?gene=A0A8V0ZME1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSR8", "url": "https://www.orthodb.org/?gene=A0A8V0ZSR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSS2", "url": "https://www.orthodb.org/?gene=A0A8V0ZSS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13742:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13742:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01858", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01858", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11934", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11934", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1538133", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1538133", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69231", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZKF7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZME1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTEGCLDEKEWWLLLVISSLYAEPGNELHWLACALYVACRKAIPTVSRGTVEGNYVSLTRILRCFEQSLIEFFNKMKKWEDMANLPSQFRERTERLERNFTVSAVIFKKYEPIFQDIFRYPQEDQPRQQRGRKQRRQPCTVTEVFQFCWVLFVHAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCPNHKELLNPNFKGLPEDFHSKDYKVSSDPPCIIEKLCSLHYGLVLEAKGIKEHFWKPYIRKLFDKKLLKGKDENLTGFLDPGNFGDSFKAINKAYEEYVLSVGNLDERIFLGEDADEEIGTLTRCLNTPSGMETAERVQVKHNLQQHFDRSKSPRVTTPLTGRKYIKESNPYVTPVSIATYSLSRLHTMLAGLKNAPSENLEQIFRACSRDPSQSIASRVKEMYEVYCQSMQAEEEFSNLSKDVASKHFRRAEVLYYKVLESVIEQERRRLGDTDLSAVLEQDVFHRSLLACCLEIVTFTYKLPGSFPFITEIFDIPVYHFYKVIEVFIRAEDGLCREVVKHLNHIEEQILESMAWKQESILWDRIRDNDNKVPSCEEVMPPQYFERSAANSVVGSPLTPRRLNEVRAESGGLGKGISSSPTTLYDRYSSPTAHPTRRRLFVDNDNTSDNGTPVRVSQQPVVNTVPVQNVNPEAVSVTPVPGQTLVTVATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGAQPQAVSGSIQPLSAQALTGTLSTQMSGATLQLPGQVTVQHITSGEPRPAQQLTAATATRSRKMGSLSLFFRKVYHLASVRLRDLSVKLDISDELRKKVWTCFEYSLMHCPEIMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQAKSHVYRSVLIKGRRRRRQSGSSDSSSQQNSPTGRSKERSKERTSRDSSPVMRSSSTLPVPHPSSAPPTPTRLTGANSDTEEEERGDLIQFYNSIYIEQIKEFALKYTSSGTDTPPLSPYPSVRISSPRRVQLSQNHAVYISPHKNVSALSHREKIFYYFSSSPSKRLKEINSMIRTGETPTKKRGILLEEDSEAPAKRICQENHTALLRRLQDVANDRGSH", "length": 1087, "header": "tr|A0A8V0ZME1-1|A0A8V0ZME1_CHICK Isoform 1 of RB transcriptional corepressor like 2 OS=Gallus gallus OX=9031 GN=RBL2 PE=3 SV=1 CANONICAL=A0A8V0ZME1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1/entry#A0A8V0ZKF7-1", "sequence": { "sequence": "MQLFPFTGNELHWLACALYVACRKAIPTVSRGTVEGNYVSLTRILRCFEQSLIEFFNKMKKWEDMANLPSQFRERTERLERNFTVSAVIFKKYEPIFQDIFRYPQEDQPRQQRGRKQRRQPCTVTEVFQFCWVLFVHAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCPNHKELLNPNFKGLPEDFHSKDYKVSSDPPCIIEKLCSLHYGLVLEAKGIKEHFWKPYIRKLFDKKLLKGKDENLTGFLDPGNFGDSFKAINKAYEEYVLSVGNLDERIFLGEDADEEIGTLTRCLNTPSGMETAERVQVKHNLQQHFDRSKSPRVTTPLTGRKYIKESNPYVTPVSIATYSLSRLHTMLAGLKNAPSENLEQIFRACSRDPSQSIASRVKEMYEVYCQSMQAEEEFSNLSKDVASKHFRRAEVLYYKVLESVIEQERRRLGDTDLSAVLEQDVFHRSLLACCLEIVTFTYKLPGSFPFITEIFDIPVYHFYKVIEVFIRAEDGLCREVVKHLNHIEEQILESMAWKQESILWDRIRDNDNKVPSCEEVMPPQYFERSAANSVVGSPLTPRRLNEVRAESGGLGKGISSSPTTLYDRYSSPTAHPTRRRLFVDNDNTSDNGTPVRVSQQPVVNTVPVQNVNPEAVSVTPVPGQTLVTVATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGAQPQAVSGSIQPLSAQALTGTLSTQMSGATLQLPGQVTVQHITSGEPRPAQQLTAATATRSRKMGSLSLFFRKVYHLASVRLRDLSVKLDISDELRKKVWTCFEYSLMHCPEIMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQAKSHVYRSVLIKGRRRRRQSGSSDSSSQQNSPTGRSKERSKERTSRDSSPVMRSSSTLPVPHPSSAPPTPTRLTGANSDTEEEERGDLIQFYNSIYIEQIKEFALKYTSSGTDTPPLSPYPSVRISSPRRVQLSQNHAVYISPHKNVSALSHREKIFYYFSSSPSKRLKEINSMIRTGETPTKKRGILLEEDSEAPAKRICQENHTALLRRLQDVANDRGSH", "length": 1069, "header": "tr|A0A8V0ZKF7-1|A0A8V0ZME1_CHICK Computationally mapped isoform of RB transcriptional corepressor like 2 OS=Gallus gallus OX=9031 GN=RBL2 PE=3 SV=1 CANONICAL=A0A8V0ZME1-1" }, "locus": { "chromosome": "11", "start_pos": 4655719, "end_pos": 4637326, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052970.1", "url": "https://www.ensembl.org/id/ENSGALT00010052970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031876.1", "url": "https://www.ensembl.org/id/ENSGALP00010031876.1" } ] } }, { "isoform_ac": "A0A8V0ZMD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1/entry#A0A8V0ZMD6-1", "sequence": { "sequence": "MDERARSEAWLSYQSMKRNYTLEGNELHWLACALYVACRKAIPTVSRGTVEGNYVSLTRILRCFEQSLIEFFNKMKKWEDMANLPSQFRERTERLERNFTVSAVIFKKYEPIFQDIFRYPQEDQPRQQRGRKQRRQPCTVTEVFQFCWVLFVHAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCPNHKELLNPNFKGLPEDFHSKDYKVSSDPPCIIEKLCSLHYGLVLEAKGIKEHFWKPYIRKLFDKKLLKGKDENLTGFLDPGNFGDSFKAINKAYEEYVLSVGNLDERIFLGEDADEEIGTLTRCLNTPSGMETAERVQVKHNLQQHFDRSKSPRVTTPLTGRKYIKESNPYVTPVSIATYSLSRLHTMLAGLKNAPSENLEQIFRACSRDPSQSIASRVKEMYEVYCQSMQAEEEFSNLSKDVASKHFRRAEVLYYKVLESVIEQERRRLGDTDLSAVLEQDVFHRSLLACCLEIVTFTYKLPGSFPFITEIFDIPVYHFYKVIEVFIRAEDGLCREVVKHLNHIEEQILESMAWKQESILWDRIRDNDNKVPSCEEVMPPQYFERSAANSVVGSPLTPRRLNEVRAESGGLGKGISSSPTTLYDRYSSPTAHPTRRRLFVDNDNTSDNGTPVRVSQQPVVNTVPVQNVNPEAVSVTPVPGQTLVTVATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGAQPQAVSGSIQPLSAQALTGTLSTQMSGATLQLPGQVTVQHITSGEPRPAQQLTAATATRSRKMGSLSLFFRKVYHLASVRLRDLSVKLDISDELRKKVWTCFEYSLMHCPEIMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQAKSHVYRSVLIKGRRRRRQSGSSDSSSQQNSPTGRSKERSKERTSRDSSPVMRSSSTLPVPHPSSAPPTPTRLTGANSDTEEEERGDLIQFYNSIYIEQIKEFALKYTSSGTDTPPLSPYPSVRISSPRRVQLSQNHAVYISPHKNVSALSHREKIFYYFSSSPSKAKGN", "length": 1033, "header": "tr|A0A8V0ZMD6-1|A0A8V0ZMD6_CHICK Computationally mapped isoform of RB transcriptional corepressor like 2 OS=Gallus gallus OX=9031 GN=RBL2 PE=3 SV=1 CANONICAL=A0A8V0ZME1-1" }, "locus": { "chromosome": "11", "start_pos": 4654992, "end_pos": 4637480, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052961.1", "url": "https://www.ensembl.org/id/ENSGALT00010052961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031867.1", "url": "https://www.ensembl.org/id/ENSGALP00010031867.1" } ] } }, { "isoform_ac": "A0A8V0ZME1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1/entry#A0A8V0ZME1-1", "sequence": { "sequence": "MRTEGCLDEKEWWLLLVISSLYAEPGNELHWLACALYVACRKAIPTVSRGTVEGNYVSLTRILRCFEQSLIEFFNKMKKWEDMANLPSQFRERTERLERNFTVSAVIFKKYEPIFQDIFRYPQEDQPRQQRGRKQRRQPCTVTEVFQFCWVLFVHAKGNFPMISDDLVNSYHLLLCALDLVYGNALQCPNHKELLNPNFKGLPEDFHSKDYKVSSDPPCIIEKLCSLHYGLVLEAKGIKEHFWKPYIRKLFDKKLLKGKDENLTGFLDPGNFGDSFKAINKAYEEYVLSVGNLDERIFLGEDADEEIGTLTRCLNTPSGMETAERVQVKHNLQQHFDRSKSPRVTTPLTGRKYIKESNPYVTPVSIATYSLSRLHTMLAGLKNAPSENLEQIFRACSRDPSQSIASRVKEMYEVYCQSMQAEEEFSNLSKDVASKHFRRAEVLYYKVLESVIEQERRRLGDTDLSAVLEQDVFHRSLLACCLEIVTFTYKLPGSFPFITEIFDIPVYHFYKVIEVFIRAEDGLCREVVKHLNHIEEQILESMAWKQESILWDRIRDNDNKVPSCEEVMPPQYFERSAANSVVGSPLTPRRLNEVRAESGGLGKGISSSPTTLYDRYSSPTAHPTRRRLFVDNDNTSDNGTPVRVSQQPVVNTVPVQNVNPEAVSVTPVPGQTLVTVATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGAQPQAVSGSIQPLSAQALTGTLSTQMSGATLQLPGQVTVQHITSGEPRPAQQLTAATATRSRKMGSLSLFFRKVYHLASVRLRDLSVKLDISDELRKKVWTCFEYSLMHCPEIMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQAKSHVYRSVLIKGRRRRRQSGSSDSSSQQNSPTGRSKERSKERTSRDSSPVMRSSSTLPVPHPSSAPPTPTRLTGANSDTEEEERGDLIQFYNSIYIEQIKEFALKYTSSGTDTPPLSPYPSVRISSPRRVQLSQNHAVYISPHKNVSALSHREKIFYYFSSSPSKRLKEINSMIRTGETPTKKRGILLEEDSEAPAKRICQENHTALLRRLQDVANDRGSH", "length": 1087, "header": "tr|A0A8V0ZME1-1|A0A8V0ZME1_CHICK Isoform 1 of RB transcriptional corepressor like 2 OS=Gallus gallus OX=9031 GN=RBL2 PE=3 SV=1 CANONICAL=A0A8V0ZME1-1" }, "locus": { "chromosome": "11", "start_pos": 4654534, "end_pos": 4637326, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052966.1", "url": "https://www.ensembl.org/id/ENSGALT00010052966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031872.1", "url": "https://www.ensembl.org/id/ENSGALP00010031872.1" } ] } }, { "isoform_ac": "A0A8V0ZSR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1/entry#A0A8V0ZSR8-1", "sequence": { "sequence": "MDERARSEAWLSYQSMKRNYTLEGNELHWLACALYVACRKAIPTVSRGTVEGNYVSLTRILRCFEQSLIEFFNKMKKWEDMANLPSQFRERTERLERNFTVSAVIFKKYEPIFQDIFRYPQEDQPRQQRGRKQRRQPCTVTEVFQFCWVLFVHAKGLPEDFHSKDYKVSSDPPCIIEKLCSLHYGLVLEAKGIKEHFWKPYIRKLFDKKLLKGKDENLTGFLDPGNFGDSFKAINKAYEEYVLSVGNLDERIFLGEDADEEIGTLTRCLNTPSGMETAERVQVKHNLQQHFDRSKSPRVTTPLTGRKYIKESNPYVTPVSIATYSLSRLHTMLAGLKNAPSENLEQIFRACSRDPSQSIASRVKEMYEVYCQSMQAEEEFSNLSKDVASKHFRRAEVLYYKVLESVIEQERRRLGDTDLSAVLEQDVFHRSLLACCLEIVTFTYKLPGSFPFITEIFDIPVYHFYKQRPSD", "length": 471, "header": "tr|A0A8V0ZSR8-1|A0A8V0ZME1_CHICK Computationally mapped isoform of RB transcriptional corepressor like 2 OS=Gallus gallus OX=9031 GN=RBL2 PE=3 SV=1 CANONICAL=A0A8V0ZME1-1" }, "locus": { "chromosome": "11", "start_pos": 4654992, "end_pos": 4643764, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052949.1", "url": "https://www.ensembl.org/id/ENSGALT00010052949.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031855.1", "url": "https://www.ensembl.org/id/ENSGALP00010031855.1" } ] } }, { "isoform_ac": "A0A8V0ZSS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1/entry#A0A8V0ZSS2-1", "sequence": { "sequence": "MDERARSEAWLSYQSMKRNYTLEGNELHWLACALYVACRKAIPTVSRGTVEGNYVSLTRILRCFEQSLIEFFNKMKKWEDMANLPSQFRERTERLERNFTVSAVIFKKYEPIFQDIFRYPQEDQPRQQRGRKQRRQPCTVTEVFQFCWVLFVHAKGLPEDFHSKDYKVSSDPPCIIEKLCSLHYGLVLEAKGIKEHFWKPYIRKLFDKKLLKGKDENLTGFLDPGNFGDSFKAINKAYEEYVLSVGNLDERIFLGEDADEEIGTLTRCLNTPSGMETAERVQVKHNLQQHFDRSKSPRVTTPLTGRKYIKESNPYVTPVSIATYSLSRLHTMLAGLKNAPSENLEQIFRACSRDPSQSIASRVKEMYEVYCQSMQAEEEFSNLSKDVASKHFRRAEVLYYKVLESVIEQERRRLGDTDLSAVLEQDVFHRSLLACCLEIVTFTYKLPGSFPFITEIFDIPVYHFYKVIEVFIRAEDGLCREVVKHLNHIEEQILESMAWKQESILWDRIRDNDNKVPSCEEVMPPQYFERSAANSVVGSPLTPRRLNEVRAESGGLGKGISSSPTTLYDRYSSPTAHPTRRRLFVDNDNTSDNGTPVRVSQQPVVNTVPVQNVNPEAVSVTPVPGQTLVTVATATVTANNGQTVTIPVQGIANENGGITFFPVQVNVGAQPQAVSGSIQPLSAQALTGTLSTQMSGATLQLPGQVTVQHITSGEPRPAQQLTAATATRSRKMGSLSLFFRKVYHLASVRLRDLSVKLDISDELRKKVWTCFEYSLMHCPEIMMDRHLDQLLMCAIYVMAKVTKEDRSFQNIMRCYRTQPQAKSHVYRSVLIKGRRRRRQSGSSDSSSQQNSPTGRSKERSKERTSRDSSPVMRSSSTLPVPHPSSAPPTPTRLTGANSDTEEEERGDLIQFYNSIYIEQIKEFALKYTSSGTDTPPLSPYPSVRISSPRRVQLSQNHAVYISPHKNVSALSHREKIFYYFSSSPSKRLKEINSMIRTGETPTKKRGILLEEDSEAPAKRICQENHTALLRRLQDVANDRGSH", "length": 1042, "header": "tr|A0A8V0ZSS2-1|A0A8V0ZME1_CHICK Computationally mapped isoform of RB transcriptional corepressor like 2 OS=Gallus gallus OX=9031 GN=RBL2 PE=3 SV=1 CANONICAL=A0A8V0ZME1-1" }, "locus": { "chromosome": "11", "start_pos": 4654992, "end_pos": 4637326, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052954.1", "url": "https://www.ensembl.org/id/ENSGALT00010052954.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031860.1", "url": "https://www.ensembl.org/id/ENSGALP00010031860.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 362, "start_aa": "Thr", "end_pos": 362, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr362", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 934, "start_aa": "Thr", "end_pos": 934, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr934", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-1538133", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1538133", "resource": "Reactome", "description": "G0 and Early G1" }, { "id": "R-GGA-69231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69231", "resource": "Reactome", "description": "Cyclin D associated events in G1" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" }, { "name": "negative regulation of G1/S transition of mitotic cell cycle", "id": "GO:2000134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" }, { "name": "promoter-specific chromatin binding", "id": "GO:1990841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990841", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1011, "end_pos": 1013, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1069, "end_pos": 1071, "annotation": "n_glycosylation_sequon" }, 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKG8-1", "uniprot_ac": "A0A8V0ZKG8", "uniprot_id": "A0A8V0ZKG8_CHICK", "mass": { "chemical_mass": 35958.0, "monoisotopic_mass": 35958.0 }, "refseq": {}, "gene_names": [ { "name": "KCTD10", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" } ] } ], "protein_names": [ { "name": "Potassium channel tetramerization domain containing 10", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCTD10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8", "locus": { "chromosome": "15", "start_pos": 6749990, "end_pos": 6760917, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021580", "url": "https://www.ensembl.org/id/ENSGALG00010021580" } ] } } ], "crossref": [ { "id": "A0A8V0ZKG8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18369", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18369", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18399", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18399", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKG8", "url": "https://www.orthodb.org/?gene=A0A8V0ZKG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKM1", "url": "https://www.orthodb.org/?gene=A0A8V0ZKM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11145", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11145", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11145:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11145:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZKG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVPSEEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNIGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVDECQAALQNKDAYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYESQDGRGPDNALLEATGGAAGRSHHLEEDEERERIERVRRIHIKRPDDRAHLHQ", "length": 318, "header": "tr|A0A8V0ZKG8-1|A0A8V0ZKG8_CHICK Isoform 1 of Potassium channel tetramerization domain containing 10 OS=Gallus gallus OX=9031 GN=KCTD10 PE=3 SV=1 CANONICAL=A0A8V0ZKG8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8/entry#A0A8V0ZKG8-1", "sequence": { "sequence": "MLVPSEEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNIGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVDECQAALQNKDAYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYESQDGRGPDNALLEATGGAAGRSHHLEEDEERERIERVRRIHIKRPDDRAHLHQ", "length": 318, "header": "tr|A0A8V0ZKG8-1|A0A8V0ZKG8_CHICK Isoform 1 of Potassium channel tetramerization domain containing 10 OS=Gallus gallus OX=9031 GN=KCTD10 PE=3 SV=1 CANONICAL=A0A8V0ZKG8-1" }, "locus": { "chromosome": "15", "start_pos": 6760322, "end_pos": 6752955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052365.1", "url": "https://www.ensembl.org/id/ENSGALT00010052365.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031293.1", "url": "https://www.ensembl.org/id/ENSGALP00010031293.1" } ] } }, { "isoform_ac": "A0A8V0ZKM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8/entry#A0A8V0ZKM1-1", "sequence": { "sequence": "MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNIGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVDECQAALQPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYESQDGRGPDNALLEATGGAAGRSHHLEEDEERERIERVRRIHIKRPDDRAHLHQ", "length": 284, "header": "tr|A0A8V0ZKM1-1|A0A8V0ZKM1_CHICK Computationally mapped isoform of Potassium channel tetramerization domain containing 10 OS=Gallus gallus OX=9031 GN=KCTD10 PE=3 SV=1 CANONICAL=A0A8V0ZKG8-1" }, "locus": { "chromosome": "15", "start_pos": 6760847, "end_pos": 6752955, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052371.1", "url": "https://www.ensembl.org/id/ENSGALT00010052371.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031297.1", "url": "https://www.ensembl.org/id/ENSGALP00010031297.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" } ], "pmid": "" }, { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" } ], "pmid": "" }, { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" } ], "pmid": "" }, { "name": "negative regulation of Rho protein signal transduction", "id": "GO:0035024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKG8" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 105, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKQ3-1", "uniprot_ac": "A0A8V0ZKQ3", "uniprot_id": "A0A8V0ZKQ3_CHICK", "mass": { "chemical_mass": 56604.0, "monoisotopic_mass": 56604.0 }, "refseq": { "ac": "NP_001026430", "name": "E3 ubiquitin-protein ligase RNF25", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026430" }, "gene_names": [ { "name": "RNF25", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "name": "RNF25", "type": "synonym", "evidence": [ { "id": "NP_001026430", "database": "RefSeq", "url": 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[ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1. On Oct 25, 2021 this sequence version replaced NP_001026430.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001026430", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026430" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNF25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3", "locus": { "chromosome": "7", "start_pos": 22090982, "end_pos": 22085601, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021588", "url": "https://www.ensembl.org/id/ENSGALG00010021588" } ] } } ], "crossref": [ { "id": "A0A8V0ZKQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16470", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16470", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23818", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23818", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424211", "url": "https://www.ncbi.nlm.nih.gov/gene/424211", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424211", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424211", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEPWEIS", "url": "https://omabrowser.org/oma/group/WEPWEIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKJ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZKJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKP7", "url": "https://www.orthodb.org/?gene=A0A8V0ZKP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKQ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZKQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13198:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13198:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001026430", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026430", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGEEVEAADWALPAEVEVLESIYLEELRVVRGRARSEPWEVSITLHPATAQDQDSQFVRCTLVLAVPPQYPIEAPDISISNPRGLSDEQIQKMLQTLRNVAEARLGTEVLYELIEKGKEILTDNNIPHGQCVICLYGFQEREAFTKTQCYHYFHSHCLARYAQHMEDEILMQQEEREQHLAPSPKQKVGVQCPVCRETLVYDLCALKAAPPPQHPLEPYRPDAKMLQHQEELRLIFKKQQEKGGIIDPEAEKNRYFISLQAPPATVDPGQAAAASEPLVSASNVDAPQAPCQASALEPARAPESKAEPGQPERPAVPKEPQSKRQRHRGERSGPRGQGRQSCSSSQEGAGEACHLSHGSRAPRGFGQRSERRPGGRHCQEFPKPHSRSKAAALAERKELCPEDSSPVADTVDLKEEHHNMERWTPEQGAEAQSREKENLAFNRSEHRAAPGCQGHHRPWDCGRWERSRVQDRGSYHRAPRGRGVFRPSGRREAHFVEKESSS", "length": 505, "header": "tr|A0A8V0ZKQ3-1|A0A8V0ZKQ3_CHICK Isoform 1 of E3 ubiquitin-protein ligase RNF25 OS=Gallus gallus OX=9031 GN=RNF25 PE=3 SV=1 CANONICAL=A0A8V0ZKQ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3/entry#A0A8V0ZKJ8-1", "sequence": { "sequence": "MAAAGEEVEAADWALPAEVEVLESIYLEELRVVRGRARSEPWEVSITLHPATAQDQDSQFVRCTLVLAVPPQYPIEAPDISISNPRGLSDEQIQKMLQTLRNVAEARLGTEVLYELIEKGKEILTDNNIPHGQCPSGRTYEREAFTKTQCYHYFHSHCLARYAQHMEDEILMQQEEREQHLAPSPKQKVGVQCPVCRETLVYDLCALKAAPPPQHPLEPYRPDAKMLQHQEELRLIFKKQQEKGGIIDPEAEKNRYFISLQAPPATVDPGQAAAASEPLVSASNVDAPQAPCQASALEPARAPESKAEPGQPERPAVPKEPQSKRQRHRGERSGPRGQGRQSCSSSQEGAGEACHLSHGSRAPRGFGQRSERRPGGRHCQEFPKPHSRSKAAALAERKELCPEDSSPVADTVDLKEEHHNMERWTPEQGAEAQSREKENLAFNRSEHRAAPGCQGHHRPWDCGRWERSRVQDRGSYHRAPRGRGVFRPSGRREAHFVEKESSS", "length": 503, "header": "tr|A0A8V0ZKJ8-1|A0A8V0ZKQ3_CHICK Computationally mapped isoform of E3 ubiquitin-protein ligase RNF25 OS=Gallus gallus OX=9031 GN=RNF25 PE=3 SV=1 CANONICAL=A0A8V0ZKQ3-1" }, "locus": { "chromosome": "7", "start_pos": 22089111, "end_pos": 22085630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052414.1", "url": "https://www.ensembl.org/id/ENSGALT00010052414.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031324.1", "url": "https://www.ensembl.org/id/ENSGALP00010031324.1" } ] } }, { "isoform_ac": "A0A8V0ZKP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3/entry#A0A8V0ZKP7-1", "sequence": { "sequence": "MAAAGEEFVRCTLVLAVPPQYPIEAPDISISNPRGLSDEQIQKMLQTLRNVAEARLGTEVLYELIEKGKEILTDNNIPHGQCVICLYGFQEREAFTKTQCYHYFHSHCLARYAQHMEDEILMQQEEREQHLAPSPKQKVGVQCPVCRETLVYDLCALKAAPPPQHPLEPYRPDAKMLQHQEELRLIFKKQQEKGGIIDPEAEKNRYFISLQAPPATVDPGQAAAASEPLVSASNVDAPQAPCQASALEPARAPESKAEPGQPERPAVPKEPQSKRQRHRGERSGPRGQGRQSCSSSQEGAGEACHLSHGSRAPRGFGQRSERRPGGRHCQEFPKPHSRSKAAALAERKELCPEDSSPVADTVDLKEEHHNMERWTPEQGAEAQSREKENLAFNRSEHRAAPGCQGHHRPWDCGRWERSRVQDRGSYHRAPRGRGVFRPSGRREAHFVEKESSS", "length": 453, "header": "tr|A0A8V0ZKP7-1|A0A8V0ZKP7_CHICK Computationally mapped isoform of Ring finger protein 25 OS=Gallus gallus OX=9031 GN=RNF25 PE=4 SV=1 CANONICAL=A0A8V0ZKQ3-1" }, "locus": { "chromosome": "7", "start_pos": 22089111, "end_pos": 22085630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052406.1", "url": "https://www.ensembl.org/id/ENSGALT00010052406.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031318.1", "url": "https://www.ensembl.org/id/ENSGALP00010031318.1" } ] } }, { "isoform_ac": "A0A8V0ZKQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3/entry#A0A8V0ZKQ3-1", "sequence": { "sequence": "MAAAGEEVEAADWALPAEVEVLESIYLEELRVVRGRARSEPWEVSITLHPATAQDQDSQFVRCTLVLAVPPQYPIEAPDISISNPRGLSDEQIQKMLQTLRNVAEARLGTEVLYELIEKGKEILTDNNIPHGQCVICLYGFQEREAFTKTQCYHYFHSHCLARYAQHMEDEILMQQEEREQHLAPSPKQKVGVQCPVCRETLVYDLCALKAAPPPQHPLEPYRPDAKMLQHQEELRLIFKKQQEKGGIIDPEAEKNRYFISLQAPPATVDPGQAAAASEPLVSASNVDAPQAPCQASALEPARAPESKAEPGQPERPAVPKEPQSKRQRHRGERSGPRGQGRQSCSSSQEGAGEACHLSHGSRAPRGFGQRSERRPGGRHCQEFPKPHSRSKAAALAERKELCPEDSSPVADTVDLKEEHHNMERWTPEQGAEAQSREKENLAFNRSEHRAAPGCQGHHRPWDCGRWERSRVQDRGSYHRAPRGRGVFRPSGRREAHFVEKESSS", "length": 505, "header": "tr|A0A8V0ZKQ3-1|A0A8V0ZKQ3_CHICK Isoform 1 of E3 ubiquitin-protein ligase RNF25 OS=Gallus gallus OX=9031 GN=RNF25 PE=3 SV=1 CANONICAL=A0A8V0ZKQ3-1" }, "locus": { "chromosome": "7", "start_pos": 22089111, "end_pos": 22085630, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052412.1", "url": "https://www.ensembl.org/id/ENSGALT00010052412.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031323.1", "url": "https://www.ensembl.org/id/ENSGALP00010031323.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424211", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424211", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LA20-1", "protein_name": "E3 ubiquitin-protein ligase RNF25", "gene_name": "Rnf25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPWQRFSDISKGLRVLPSEVEVLESIYLDELQVMKGNGRSPWEIFITLHPATAEVQDSQFVCFTLVLQVPVQYPHEVPQISIRNPRGLSDEQIHKISQALGHVAKEGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELNTQEQEQQHVVTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEELKRLYQRQQEKGGIIDLEAERNRYFISLQQPPAALEPESVVDVSRGPQPPNTLSAEQSTSLAAQSTLPTPLPMATQYVYEKTSGAGPNQQRLGETQKSMLDPPRPGRGSWRQYDRRHPKGGECCAPKGTSEIQELPPPEKPLKETVDLKAEPRNKGLTGHPQEKGPGSWQGPSARRTRDCARWERSKNRTPGSSYPHLPRGQGAYRSGTRREPLGLESEEGS", "length": 455 }, "evidence": [ { "id": "A0A8V0ZKQ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKQ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MWS4-1", "protein_name": "E3 ubiquitin-protein ligase RNF25", "gene_name": "RNF25", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAVSASVAAGDEDWVLPSEVEVLESIYLDELQVVKGNGRSSPWEIYITLHPATAEDQDSQYVCFTLVLQVPTQYPHEVPQISIRNPRGLSDEQIHKISQALSHVAEAGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEHELQAQGREREQERQHAAPEQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPDAESLRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQQPPAPLEPESAIDVSRGSHQPSTLATEPSTTSATHTALSVSLPLASQYTCEKTPGAGPHLPKLGETQKAVLDPRRASRGPWRQPERRHLKGGECNTLKGTSDTQKLQSPEGPLKESMDLKPESHNQGGKGPPQDKGPGEWQGPPPRRTRDCAHWERAKNRTPASSYPRLPRGRGAYRPGPRREPVSLESEDGS", "length": 459 }, "evidence": [ { "id": "A0A8V0ZKQ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKQ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LCK8-1", "protein_name": "E3 ubiquitin-protein ligase RNF25", "gene_name": "RNF25", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAASASATAGEEDWVLPSEVEVLESIYLDELQVVKGNSRSSPWEISITLHPATAEDQDSQYVCFTLVLQVPAQYPHEVPQISIRNPRGLSDEQIHKISQALSHVAEAGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEHELQAQGREQEQQRQHAAAKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPDAESLRQQAERKRLYQRQQERGGIIDLEAERNRYFISLQQPPAPLEPESAVDASRGSHPPSALATEPSISSTAQTTLSPPLPVTSQYTCEKIPGLGPNQQKLGETQRAMPEPPRASRGPWRQAERRHLKGGECSVLKGTIDTQELPPPEGPLKEAMDLKPESRNQGVEGPPQEKGPGNWQDPPPRRTRDCARWERSKGRTPASSYPRLPRGRGAYRPGTRREPVSLESEDGS", "length": 459 }, "evidence": [ { "id": "A0A8V0ZKQ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKQ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q96BH1-1", "protein_name": "E3 ubiquitin-protein ligase RNF25", "gene_name": "RNF25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASASAAAGEEDWVLPSEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQYVCFTLVLQVPAEYPHEVPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQEQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEERKRLYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLPRGQGAYRPGTRRESLGLESKDGS", "length": 459 }, "evidence": [ { "id": "A0A8V0ZKQ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKQ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QZR0-1", "protein_name": "E3 ubiquitin-protein ligase RNF25", "gene_name": "Rnf25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASASTAAGEEDWVLPSEVEVLESIYLDELQVMKGNGRSPWEIFITLHPATAEVQDSQFVCFTLVLRIPVQYPHEVPQISIRNPRGLSDEQIHKISQALGHVAKEGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELTTQEQEQERQHVVTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEELKLLYQRQQEKGGIIDLEAERNRYFISLQQPPAALEPESAVDVSREPQPPNALSAEQSTSLADQSTLPTSLPMTTQYTYEKTSGAGPNQQRPGETQKSVLDPPRHGRGSWRQYDRRHPKGGECCTPKGTSEIHELPPPEKPLKETVDLKAEPRNKGLTGHPQEKGPGSWQGPSARRTRDCARWERSKNRTPGSCYPHLPRGQGAYRSGTRREPLGLESEEGS", "length": 456 }, "evidence": [ { "id": "A0A8V0ZKQ3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKQ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ], "pmid": "" }, { "name": "NF-kappaB binding", "id": "GO:0051059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ], "pmid": "" }, { "name": "protein K6-linked ubiquitination", "id": "GO:0085020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0085020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ], "pmid": "" }, { "name": "protein-RNA covalent cross-linking repair", "id": "GO:0160127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 445, "end_pos": 447, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 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"ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1P2G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P2G0" } ] } ] }, { "uniprot_ac": "Q5ZKX6", "gene_name": "UBE2F", "activity": [ { "ec_number": "2.3.2.34", "activity": "[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine + [E2 NEDD8-conjugating enzyme]-L-cysteine = [E1 NEDD8-activating enzyme]-L-cysteine + [E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine.", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] }, { "ec_number": "2.3.2.34", "activity": "", "evidence": [ { "id": "Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 134, "end_pos": 199, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" }, { "id": "PS50908", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RWD", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 127, "start_aa": "Ala", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 445, "end_pos": 447 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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{ "uniprot_canonical_ac": "A0A8V0ZKK3-1", "uniprot_ac": "A0A8V0ZKK3", "uniprot_id": "A0A8V0ZKK3_CHICK", "mass": { "chemical_mass": 122815.0, "monoisotopic_mass": 122815.0 }, "refseq": { "ac": "NP_001292573", "name": "ubiquitin-protein ligase E3B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292573" }, "gene_names": [ { "name": "UBE3B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "name": "UBE3B", "type": "synonym", "evidence": [ { "id": "NP_001292573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292573" } ] } ], "protein_names": [ { "name": "Ubiquitin-protein ligase E3B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.26", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3/entry#names_and_taxonomy" } ] }, { "name": "HECT-type ubiquitin transferase E3B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-protein ligase E3B-like", "type": "synonym", "evidence": [ { "id": "NP_001292573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292573" } ] }, { "name": "ubiquitin-protein ligase E3B", "type": "synonym", "evidence": [ { "id": "NP_001292573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292573" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.25990.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000260.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292573", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292573" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBE3B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3", "locus": { "chromosome": "15", "start_pos": 6779607, "end_pos": 6761204, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021595", "url": "https://www.ensembl.org/id/ENSGALG00010021595" } ] } } ], "crossref": [ { "id": "A0A8V0ZKK3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "776286", "url": "https://www.ncbi.nlm.nih.gov/gene/776286", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:776286", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776286", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTKCTAP", "url": "https://omabrowser.org/oma/group/NTKCTAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKK3", "url": "https://www.orthodb.org/?gene=A0A8V0ZKK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKR5", "url": "https://www.orthodb.org/?gene=A0A8V0ZKR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRD9", "url": "https://www.orthodb.org/?gene=A0A8V0ZRD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45700", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45700", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45700:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45700:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001292573", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSASQSSKAQFLDKARQAREERRELKERERAAVQIQALVRRFLCRCHLQKEIRREVEDFFGATESGASKRSALSVFRIARKLLFVFNHKEDKERFEKLCRCILNSMDVENEPKVWYVSLALSKDLTLLWIKQIKDILWFCCEFLKQLKPDILQDSRLVNLHLTMLVTFTDTSTWKILRGKGETLRPAMNHICANIMGHLNQKGFYSVLQILLTNGLARSRPSLSKGSLTAIFSLALRPVVAAQFSDNLLRSFLIHIMSVPAIMTHLATLTPERLAVIESHDLLRKFIIFLSREAQCRDVCVCLEGSHTLCLLGNLVYLGSLNDKVLEDETAHFVGVLIHMLSYCQKYVSQKKSNLTHWHPVLGWFSQTVDYGLNESMPLLTKQLQHLWGVHMIRILFSDVLSKKLLENQEIAQLPTQPVSPQNSLPMKNLFKRAFQKSASVRNILKPVGGKRVDSAEVQKVCSICVLYQTTLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPQGGLKLFLECLNNDTEESKRLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENARGETLELFHSVHGWLMVLYERDCRRRFAPEDHWLRKDLKPSVLFQELDKDKKRAQLLLQYIPHVIPHKNRVLLFRNMVTKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQNAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKKVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDISDLGLTLSYDEDVMGQLVCHELVPGGKTIPVTNENKISYIHLMAHFRMHTQIKSQTAALISGFRSIIKPEWIRMFSAPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILANDFSPEERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSKKSILREKLRYAISMNTGFELS", "length": 1070, "header": "tr|A0A8V0ZKK3-1|A0A8V0ZKK3_CHICK Isoform 1 of Ubiquitin-protein ligase E3B OS=Gallus gallus OX=9031 GN=UBE3B PE=4 SV=1 CANONICAL=A0A8V0ZKK3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3/entry#A0A8V0ZKK3-1", "sequence": { "sequence": "MFSASQSSKAQFLDKARQAREERRELKERERAAVQIQALVRRFLCRCHLQKEIRREVEDFFGATESGASKRSALSVFRIARKLLFVFNHKEDKERFEKLCRCILNSMDVENEPKVWYVSLALSKDLTLLWIKQIKDILWFCCEFLKQLKPDILQDSRLVNLHLTMLVTFTDTSTWKILRGKGETLRPAMNHICANIMGHLNQKGFYSVLQILLTNGLARSRPSLSKGSLTAIFSLALRPVVAAQFSDNLLRSFLIHIMSVPAIMTHLATLTPERLAVIESHDLLRKFIIFLSREAQCRDVCVCLEGSHTLCLLGNLVYLGSLNDKVLEDETAHFVGVLIHMLSYCQKYVSQKKSNLTHWHPVLGWFSQTVDYGLNESMPLLTKQLQHLWGVHMIRILFSDVLSKKLLENQEIAQLPTQPVSPQNSLPMKNLFKRAFQKSASVRNILKPVGGKRVDSAEVQKVCSICVLYQTTLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPQGGLKLFLECLNNDTEESKRLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENARGETLELFHSVHGWLMVLYERDCRRRFAPEDHWLRKDLKPSVLFQELDKDKKRAQLLLQYIPHVIPHKNRVLLFRNMVTKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQNAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKKVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDISDLGLTLSYDEDVMGQLVCHELVPGGKTIPVTNENKISYIHLMAHFRMHTQIKSQTAALISGFRSIIKPEWIRMFSAPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILANDFSPEERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSKKSILREKLRYAISMNTGFELS", "length": 1070, "header": "tr|A0A8V0ZKK3-1|A0A8V0ZKK3_CHICK Isoform 1 of Ubiquitin-protein ligase E3B OS=Gallus gallus OX=9031 GN=UBE3B PE=4 SV=1 CANONICAL=A0A8V0ZKK3-1" }, "locus": { "chromosome": "15", "start_pos": 6777948, "end_pos": 6762010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052422.1", "url": "https://www.ensembl.org/id/ENSGALT00010052422.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031329.1", "url": "https://www.ensembl.org/id/ENSGALP00010031329.1" } ] } }, { "isoform_ac": "A0A8V0ZKR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3/entry#A0A8V0ZKR5-1", "sequence": { "sequence": "MFSASQSSKAQFLDKARQAREERRELKERERAAVQIQALVRRFLCRCHLQKEIRREVEDFFGATESGASKRSALSVFRIARKLLFVFNHKEDKERFEKLCRCILNSMDVENEPKVWYVSLALSKDLTLLWIKQIKDILWFCCEFLKQLKPDILQDSRLVNLHLTMLVTFTDTSTWKILRGKGETLRPAMNHICANIMGHLNQKGFYSVLQILLTNGLARSRPSLSKGSLTAIFSLALRPVVAAQFSDNLLRSFLIHIMSVPAIMTHLATLTPERLAVIESHDLLRKFIIFLSREAQCRDVCVCLEGSHTLCLLGNLVYLGSLNDKVLEDETAHFVGVLIHMLSYCQKYVSQKKSNLTHWHPVLGWFSQTVDYGLNESMPLLTKQLQHLWGVHMIRILFSDVLSKKLLENQEIAQLPTQPVSPQNSLPMKNLFKRAFQKSASVRNILKPVGGKRVDSAEVQKVCSICVLYQTTLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPQGGLKLFLECLNNDTEESKRLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENARGETLELFHSVHGWLMVLYERDCRRRFAPEDHWLRKDLKPSVLFQELDKDKKRAQLLLQYIPHVIPHKNRVLLFRNMVTKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQNAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKKVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDISDLGLTLSYDEDVMGQLVCHELVPGGKTIPVTNENNYIHLMAHFRMHTQIKSQTAALISGFRSIIKPEWIRMFSAPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILANDFSPEERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKKEPEKMQNGDAWKCIWKSSVESFFLIISVI", "length": 1053, "header": "tr|A0A8V0ZKR5-1|A0A8V0ZKR5_CHICK Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=UBE3B PE=4 SV=1 CANONICAL=A0A8V0ZKK3-1" }, "locus": { "chromosome": "15", "start_pos": 6779498, "end_pos": 6762010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052426.1", "url": "https://www.ensembl.org/id/ENSGALT00010052426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031333.1", "url": "https://www.ensembl.org/id/ENSGALP00010031333.1" } ] } }, { "isoform_ac": "A0A8V0ZRD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3/entry#A0A8V0ZRD9-1", "sequence": { "sequence": "MFSASQSSKAQFLDKARQAREERRELKERERAAVQIQALVRRFLCRCHLQKEIRREVEDFFGATESGASKRSALSVFRIARKLLFVFNHKEDKERFEKLCRCILNSMDVENEPKVWYVSLALSKDLTLLWIKQIKDILWFCCEFLKQLKPDILQDSRLVNLHLTMLVTFTDTSTWKILRGKGETLRPAMNHICANIMGHLNQKGFYSVLQILLTNGLARSRPSLSKGSLTAIFSLALRPVVAAQFSDNLLRSFLIHIMSVPAIMTHLATLTPERLAVIESHDLLRKFIIFLSREAQCRDVCVCLEGSHTLCLLGNLVYLGSLNDKVLEDETAHFVGVLIHMLSYCQKYVSQKKSNLTHWHPVLGWFSQTVDYGLNESMPLLTKQLQHLWGVHMIRILFSDVLSKKLLENQEIAQLPTQPVSPQNSLPMKNLFKRAFQKSASVRNILKPVGGKRVDSAEVQKVCSICVLYQTTLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPQGGLKLFLECLNNDTEESKRLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENARGETLELFHSVHGWLMVLYERDCRRRFAPEDHWLRKDLKPSVLFQELDKDKKRAQLLLQYIPHVIPHKNRVLLFRNMVTKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQNAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKKVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDISDLGLTLSYDEDVMGQLVCHELVPGGKTIPVTNENKISYIHLMAHFRMHTQIKSQTAALISGFRSIIKPEWIRMFSAPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILANDFSPEERAMFLKDTGDTLGSVLRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSKKSILREKLRYAISMNTGFELS", "length": 1039, "header": "tr|A0A8V0ZRD9-1|A0A8V0ZRD9_CHICK Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Gallus gallus OX=9031 GN=UBE3B PE=4 SV=1 CANONICAL=A0A8V0ZKK3-1" }, "locus": { "chromosome": "15", "start_pos": 6777948, "end_pos": 6762010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052429.1", "url": "https://www.ensembl.org/id/ENSGALT00010052429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031336.1", "url": "https://www.ensembl.org/id/ENSGALP00010031336.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:776286", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776286", "resource": "KEGG Pathway" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0E7-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "Ube3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTVSQTSRAWFLDKARQAREERLEQKERERSAVLIQALVRSFLCRRRLHKDVRREIDEFFTADESGSSKRSALCIFKIARKLLFICKTTEDNERMEKLCRSILSSMDAENEPKVWYVSLALSKDLTLLWIKQIKSILWYCCELLGQLKPEILQDSRLITLYLTMLVTFTDTSTWKILRGKGESLRPALNHICANIMGHLNQRGFYSVLQVLLTRGLARPRPCLSKSTLTAAFTLALRPVVAAQFSDSLMRPFIIHIMSVPALVAHLSTMAPERLGVLESHDMLRKFIVFLRDRDRCQDACESLEGCHTLCLMGNLLHLGSLNLKMLEEETDGFVSLLTQMLCYCQKYVSQKKSNLTHWHPVLGWFSQSVDYGLNDSMYLITKQLQFLWGVPLIRIFFSDILSKKLLEPPEPVPAQPQPSSPQTVLPVKSLLKRAFQKSASVRNILKPVGGRRVDSTEVRKVCSICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTGESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAKGETLELFQSVHGWLMVLYERDCRRRFAPEDHWLRKDLKPGVLFQELDKDRKRAQLILLHIPHVVPHKNRVLLFRNMVIKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLPQHAMKGAIRVKFVSDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQMLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDVADLGLTLSYDEDVMGQLVCHELVPGGKTIPVTDENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIVWLWDILASDFTPGERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "length": 1070 }, "evidence": [ { "id": "A0A8V0ZKK3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKK3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287BH46-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "UBE3B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTVSQTSRAWFIDRARQAREERLVQKERERAAVDIQAHVRSFLCRRRLQREIRREIDEFLKADDSGSSKRSALCIFKIARKLLFLFRIKEDNERFEKLCRCILSSMEAENEPKVWYVSLALSKDLTLLWIKQIKDILWYCCEFLKQLKPEILQDSKLITLYLTMLVTFTDTSTWKILRGKGESLRPAMNHICANIMGHLNQHGFYSVLQVLLTRGLARPRPCLSKGTLTAAFSLALRPVIAAQFSDNLLRPFLIHIVSVPALVTHLSTVTPERLTVLESHDMLHKFITFLRDEDRCRDVCESLEGCHTLCLMGNLLHLGSLSPRVLEEETDGFVSLLTQMLCYCQKYVSQKKSNLTHWHPVLGWFSQSVDYGLNESMPLITKQLQFLWGVPLIRIFFNDILSKKLLENPEPAHVPPASSPQNVLPVKTLLKRAFQKSASVRNILRPVGGKRVDSAEVQKVCNICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTEESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAKGETLELFHSVHGWLMVLYERDCRRRFAPEDHWLRKDLKPSVLFQELDKDRKRAQLILQYIPHVIPHKNRVLLFRNMVTKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLLGHHHSIFYSSVDELPSLDSEFYKNLTSIKRYDGDIADLGLTLSYDEDVMGQLVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWTRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "length": 1069 }, "evidence": [ { "id": "A0A8V0ZKK3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKK3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8N1YZY7-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "ube3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFTATQTSKTQFLDKARVAREERKGHKEKERAATQIQALVRRFLCRCRLQKEIRKEVDDFIAVSDAGPTKRNALSIFKIARKLLFILSKDDKLRFEKLCRIILNSMDVENEPKVWYVSLALSKDLTILWLKQIKDVLWVSCEFLKKLKPDILQDNKLVTLYLTMLITFTDTSTWKIIRGKGEALKPALNRICENIMGHLNQKGFYSVLQILLTNGLARSRPSLSKGTLTAIFTLSLRPVIAAHFSDNLLRSFLLHVMSVPAFISHLNTLTPDCMITIQTHDLFRKFVLFLSREEQCLDICVCLEGSHTLCLLGNLIQLGYFNVKVLEQEAGHFVKDLTDMLSYCQRYVSQKKSNLTHWHPVLGWFSQTVDYGLNESMPLVTKQLQCLWGVPVICTLFCDVLSKKLETQDPTPPPAPQPSSLQNNLPVKNLFKRAFQKSASVRNILKPVGGKRVDSAEVQKVCSICVLYQTALTTLTQIRLQILTGLTYLDELLPKLWAFICELGPQGGLRLFLECLNNDTEESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKMEELVTISSFLNTFVYKMVWDGILENAKGEKLDLFHSVHGWLMVLYERDCRRRFTPEDHWLRKDLKPSLLFQELEKGKKRAQLLLQYIPHVIPHKNRVLLFRNIVTKEKETLGLVETSSASPHVTHITIRRSRMLEDGYDQLRRLPVNSIKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKKVFNPALNLFKTTSGNERLYPSPTSSIHENHLQLFEFVGKMLGKAMYEGIVVDVPFASFFLSQVLGHHHSTFYSSIDELPSLDSEFYKNLTSIKRYDGDVSDLGLTLSYDEEVMGQLVCHELIPGGKTMPVTNENKISYIHLMAHFRMHTQIKEQTAAFIRGFRSIINPEWLHMFSTPEVQRLISGDNAEIDLDDLKKHTVYYGGFHSSHRVILWLWDILSSDFTPDERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSKKSILRDKLRYAISMNTGFELS", "length": 1069 }, "evidence": [ { "id": "A0A8V0ZKK3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKK3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BCU1-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "UBE3B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFTVSQTSRAWFIDRARQAREERLVQKERERAAVEIQAHIRSFLCRRRLQREIRREIDEFFKAEDSGSSKRSALCIFKIARKLLFLFRIKEDNERFEKLCRCILSSMEAENEPKVWYVSLALSKDLTLLWIKQIKDILWYCCEFLEQLKPEILQDSKLITLYLTMLVTFTDTSTWKILRGKGESLRPALNHICANIMGHLNQRGFYPVLQILLTRGLARPRPCLSKGTLTAAFSLAMRPVLAAQFSDNLIRPFLIHIVSVPALVTHLSTVTPERLTVLESHDMLRKFIAFLRDEDRCRDVCESLEGCHTLCLMGNLLQLGSLSPRVLEEETDGFVSLLTQMLCYCQKYVSQKKSNLTHWHPVLGWFSQSVDYGLNESMPLITKQLQFLWGVPLIRVFFSDILSKKLLETQEPAHAPPASPQNVLPVKTLLKRAFQKSASVRNILRPVGGKRVDSTEAQKVCRVCVLYQTSLATLTQIRLQVLTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTEESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAKGETLELFQSVHGWLMVLYERDCRRRFAPEDHWLRKDLKPSVLFQELDKDRKRAQLILQYIPHVIPHKNRVLLFRNMVTKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDIADLGLTLSYDEDVMGQLVCHELVPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPEERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "length": 1068 }, "evidence": [ { "id": "A0A8V0ZKK3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKK3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HI81-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "Ube3b", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFTVSQTSRAWFIDRARQAREERLGQKERERSAVIIQALVRSFLCRRRLHRDIRIEIDEFFKRDDSGSSKRSALCIFKIARKLLFIYKTKEDHERLEKLCRSILSSMDAENEPKVWYVSLALSKDLTLLWIKQIKSILWYCCELLEQLKPEILQDSRLITLHLTMLVTFTDTSTWKILRGKGESLRPALNHICANIMGHLNQRGFYSVLQVLLTRGLARSRPCLSTGTLTATFSLALRPVVASQFSDNLMRPFVIHIMSVPALVTHLSTVAPERLSVLESHDMLRKFIVFLRDRDRCLDACESLEGCHTLCLMGNILHLGSLNPKVLEEETDGFVSLLTQMLCYCQKYVSQKKSNLTHWHPVLGWFSQSVDYGLNESMYLITKQLQFLWGVPLIRIFFCDILSKKLLEHPEPAPAQPSSPQNVLPVKSLLKRAFQKSASVRNILRPVGGRRVDSAEVQKVCSICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTGESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIAENAKGETLELFQSVHGWLMVLYERDCRRRFAPEDHWLRKDLKPGVLFQELDRDRKRAQLILQHIPHVVPHKNRVLLFRNMVTKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQMLGHHHSIFYSSVDELPSLDSEFYKNLTSIKRYDGDIADLGLTLSYDEDVMGQLVCHELVPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEMDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "length": 1068 }, "evidence": [ { "id": "A0A8V0ZKK3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKK3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q7Z3V4-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "UBE3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFTLSQTSRAWFIDRARQAREERLVQKERERAAVVIQAHVRSFLCRSRLQRDIRREIDDFFKADDPESTKRSALCIFKIARKLLFLFRIKEDNERFEKLCRSILSSMDAENEPKVWYVSLACSKDLTLLWIQQIKNILWYCCDFLKQLKPEILQDSRLITLYLTMLVTFTDTSTWKILRGKGESLRPAMNHICANIMGHLNQHGFYSVLQILLTRGLARPRPCLSKGTLTAAFSLALRPVIAAQFSDNLIRPFLIHIMSVPALVTHLSTVTPERLTVLESHDMLRKFIIFLRDQDRCRDVCESLEGCHTLCLMGNLLHLGSLSPRVLEEETDGFVSLLTQTLCYCRKYVSQKKSNLTHWHPVLGWFSQSVDYGLNESMHLITKQLQFLWGVPLIRIFFCDILSKKLLESQEPAHAQPASPQNVLPVKSLLKRAFQKSASVRNILRPVGGKRVDSAEVQKVCNICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTEESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAKGETLELFQSVHGWLMVLYERDCRRRFTPEDHWLRKDLKPSVLFQELDRDRKRAQLILQYIPHVIPHKNRVLLFRTMVTKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLSYDEDVMGQLVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "length": 1068 }, "evidence": [ { "id": "A0A8V0ZKK3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKK3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ES34-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "Ube3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTVSQTSRAWFIDRARQAREERLVQKERERSAVTIQALVRSFLCRRRLHRDIRKEIDEFFSADESGSSKRSALCIFKIARRLLFICKTTEDSERLEKLCRSILNSMDAENEPKVWYVSLALSKDLTLLWIKQIKSILWHCCELLGQLKPEILQDSRLITLYLTMLVTFTDTSTWKILRGKGESLRPALNHICANIMGHLNQRGLYSVLQVLLTRGLARPRPCLSKGMLTAAFSLALRPVVAAQFSDNLMRPFIIHVMSVPALVAHLSTVAPERLGVLESHDMLRKFIVFLRDRDRCRDACESLEGCHTLCLMGNLLHLGSLSLRLLEEEMDGFVSALTQMLCYCQKYVAQKKSNLTHWHPVLGWFSQPVDYGLNDSMYLITKQLQFLWAVPLIRILFSDILSRKLLEHAEPAPVQPQPSSPQTVLPVKSLLKRAFQKSASVRNILRPVGGRRVDSAEVRKVCNICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTGESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAKGETLELFQSVHGWLMVLYERDCRRRFAPEDHWLRRDLKPGVLFQELDKDRRRAQLVLQHIPHVVPHKNRVLLFRNMVIKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQMLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDIADLGLTLSYDEDVMGQLVCHELVPGGKTIPVTDENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPEERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS", "length": 1070 }, "evidence": [ { "id": "A0A8V0ZKK3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VSS9-1", "protein_name": "Ubiquitin-protein ligase E3B", "gene_name": "NM_140022.1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFAQNQKASFLEQTKAAREERALEKRREQAAILLQSTLKGYAARRKYQKRIILDFDAMFTENHDDKDAELELVASNVYPVLRRYLTQIRLDKSDVRARERLERICRYIIKAMESENTKLSYAALCLFKERSLPWIAHIKILLTNCLTLLPELKPENHADSLSLALFLHTLVVFTAPKSWAILRNAQFEKLQPAMQKICCNIQGHLVQHDFYKIMRLVLIRGTVREELSVKPVTLVAIITLCLRPLIDGNFSRNLLAKFLSEILSVPALIYHLQQSVPQCLEQFSSMGLLKKALSISGDVQWFEEFGTSMPGTKSLAFLGNIVNLFNIDGQGESKELAYPLLTETTTSLLELIPNTVTTKGVFTQWHELLGWHTPGPEPAQNQNVALIKKQFHMLWDHRCIKLLLGDLLKQINLNYERIEFQSPQQPSISNLLRRALERSSTRGVNLMGVASSKQSKQQWRKLDSAEVVQVSRICGMYYAALNTLSQMKLDILTGICYSDNVLYDIWLLITSLGPNCGMKEYLELLKSETNLQKPQTAMLMLFCDCMTHYVTILDEHEMYTEQNPFKLNDYVLLTYFLNNILYKLINDNLLAGAKNIVQHPVFLSLHTLMLCLYRRDCRRPFTPPKHWLIPEVKPSTFINDLEKAKRNAMLLLAKMPHIIPHEDRVKLFRKFVQNEKAVMGLTESACASPRSALIVIHRDRIVEDGYRQLAAQPTQALKGVIRVRFINQQGLHEAGIDQDGVFKEFLEETIKKVFDPSLNLFKTTSDQRLYPSPISYVQDNHLELFEFVGRMLGKAVYEGIVVDVPFASFFLSQLLGQTQQALYSCMDELPSLDNELYRSLTFIKHYKQDVSDLNLTFSVDQDVMGKIVTLALHPGGKARVVNDHNKLVYIHYMAFFHMNTQIREQTIAFNRGFRSIVNPEWLSLFSPPELQRLISGDTSPLDLKDLQKHTHYYGGFHDTHQVVCWLWDILAKDFTEEERKLFLKFVTSCSKPPLLGFAHLEPPFSIRCVEVSDDEDTGDTIGSVIRGFFAIRKKDPLNRLPTSSTCFNLLKLPNYQKKSTLRDKLRYAVSSNTGFELS", "length": 1078 }, "evidence": [ { "id": "A0A8V0ZKK3", "url": "https://omabrowser.org/oma/group/A0A8V0ZKK3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ], "pmid": "" }, { "name": "regulation of postsynapse assembly", "id": "GO:0150052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1046, "end_pos": 1048, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 831, "end_pos": 833, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-983140", "name": "Transfer of Ub from E2 to substrate and release of E2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983140", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983140" } ] }, { "id": "R-GGA-983147", "name": "Release of E3 from polyubiquitinated substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A0X2-1", "A0A8V1A2W7-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YYC5-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983147", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983147" } ] }, { "id": "R-GGA-983156", "name": "Polyubiquitination of substrate", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983156", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983156" } ] }, { "id": "R-GGA-983157", "name": "Interaction of E3 with substrate and E2-Ub complex", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X324-1", "A0A8V0XEM6-1", "A0A8V0XJC4-1", "A0A8V0XQR1-1", "A0A8V1AC19-1", "A0A8V1AC55-1", "A0A8V1AKB8-1", "A0A8V1ALH0-1", "F1NL19-1", "F1NRC6-1", "F1NTZ8-1", "A0A8V0YHL7-1", "A0A8V0YPW4-1", "A0A8V0YRM6-1", "A0A8V0YV22-1", "A0A8V0YVP3-1", "A0A8V0Z2L5-1", "F1NL77-1", "E1C982-1", "A0A3Q2UC96-1", "Q5ZKX6-1", "Z4YJC3-1", "A0A8V0XQU7-1", "A0A8V0Y5C9-1", "A0A8V1AL09-1", "A0A8V1AML5-1", "A0A8V1AP69-1", "F1NVY8-1", "R4GIV8-1", "A0A8V0ZJ49-1", "A0A8V0ZJV9-1", "A0A8V0ZL18-1", "A0A8V0ZM17-1", "A0A8V0ZSH4-1", "A0A8V0ZVX3-1", "A0A8V0ZW26-1", "A0A8V1A0Z6-1", "A0A8V0ZZH3-1", "A0A8V1A052-1", "A0A8V1A0X2-1", "A0A8V1A1I4-1", "A0A8V1A2W7-1", "A0A8V1A5P4-1", "A0A8V1A7T1-1", "A0A8V0XTY5-1", "A0A8V0Y5B5-1", "A0A8V0YL05-1", "A0A8V0Z082-1", "A0A8V0ZS27-1", "A0A8V1A9M0-1", "E1BZ35-1", "E1C3Q9-1", "F1NC08-1", "F1P2G0-1", "A0A8V0YY10-1", "A0A8V0YYC5-1", "A0A8V0Z1W7-1", "A0A8V0Z4C8-1", "A0A8V0Z596-1", "A0A1D5P284-1", "A0A8V0ZF21-1", "A0A3Q2U2G8-1", "A0A8V1A4H7-1", "A0A8V1A1N8-1", "A0A8V1A233-1", "A0A8V1A7P9-1", "A0A8V1ACU3-1", "A0A8V0ZSA3-1", "E1C656-1", "A0A8V0Y0Q7-1", "A0A8V0Y059-1", "A0A8V0Y5C7-1", "A0A8V0YCS7-1", "A0A8V0YDQ1-1", "A0A8V0YFD9-1", "A0A8V0YGF4-1", "A0A8V0YJK8-1", "A0A8V0YLY7-1", "A0A1D5NVE2-1", "A0A8V0ZKK3-1", "A0A8V0ZKQ3-1" ], "evidence": [ { "id": "R-GGA-983157", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983157" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NVE2", "gene_name": "UBE2Q1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A1D5NVE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NVE2" } ] } ] }, { "uniprot_ac": "A0A1D5P284", "gene_name": "UBR2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A1D5P284", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P284" } ] } ] }, { "uniprot_ac": "A0A3Q2U2G8", "gene_name": "TRIM9", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A3Q2U2G8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U2G8" } ] } ] }, { "uniprot_ac": "A0A3Q2UC96", "gene_name": "NEDD4L", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A3Q2UC96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UC96" } ] } ] }, { "uniprot_ac": "A0A8V0X324", "gene_name": "UBE2E1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0X324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X324" } ] } ] }, { "uniprot_ac": "A0A8V0XEM6", "gene_name": "HERC2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XEM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEM6" } ] } ] }, { "uniprot_ac": "A0A8V0XJC4", "gene_name": "UBE3D", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0XJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJC4" } ] } ] }, { "uniprot_ac": "A0A8V0XQR1", "gene_name": "UBE2H", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V0XQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQR1" } ] } ] }, { "uniprot_ac": "A0A8V0XQU7", "gene_name": "RNF6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQU7" } ] } ] }, { "uniprot_ac": "A0A8V0XTY5", "gene_name": "SH3RF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0XTY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTY5" } ] } ] }, { "uniprot_ac": "A0A8V0Y059", "gene_name": "UBE2D1", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Y059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y059" } ] } ] }, { "uniprot_ac": "A0A8V0Y0Q7", "gene_name": "RNF144B", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0Y0Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0Q7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5B5", "gene_name": "LTN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5B5" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C7", "gene_name": "CBLL1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Y5C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C7" } ] } ] }, { "uniprot_ac": "A0A8V0Y5C9", "gene_name": "HERC3", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0Y5C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y5C9" } ] } ] }, { "uniprot_ac": "A0A8V0YCS7", "gene_name": "RNF19A", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YCS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCS7" } ] } ] }, { "uniprot_ac": "A0A8V0YDQ1", "gene_name": "WWP1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YDQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YFD9", "gene_name": "UBE2D2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YFD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFD9" } ] } ] }, { "uniprot_ac": "A0A8V0YGF4", "gene_name": "MYLIP", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YGF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGF4" } ] } ] }, { "uniprot_ac": "A0A8V0YHL7", "gene_name": "RNF114", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YHL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHL7" } ] } ] }, { "uniprot_ac": "A0A8V0YJK8", "gene_name": "RNF14", "activity": [ { "ec_number": "2.3.2.31", "activity": "[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] }, { "ec_number": "2.3.2.31", "activity": "", "evidence": [ { "id": "A0A8V0YJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJK8" } ] } ] }, { "uniprot_ac": "A0A8V0YL05", "gene_name": "UBE3A", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0YL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL05" } ] } ] }, { "uniprot_ac": "A0A8V0YLY7", "gene_name": "MKRN4P", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YLY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLY7" } ] } ] }, { "uniprot_ac": "A0A8V0YPW4", "gene_name": "UBE2J2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YPW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPW4" } ] } ] }, { "uniprot_ac": "A0A8V0YRM6", "gene_name": "RNF130", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRM6" } ] } ] }, { "uniprot_ac": "A0A8V0YV22", "gene_name": "RNF4", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YV22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YV22" } ] } ] }, { "uniprot_ac": "A0A8V0YVP3", "gene_name": "RBBP6", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YVP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVP3" } ] } ] }, { "uniprot_ac": "A0A8V0YY10", "gene_name": "UBE2D3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0YY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YY10" } ] } ] }, { "uniprot_ac": "A0A8V0YYC5", "gene_name": "ZNRF2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYC5" } ] } ] }, { "uniprot_ac": "A0A8V0Z082", "gene_name": "UBE2B", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z082", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z082" } ] } ] }, { "uniprot_ac": "A0A8V0Z1W7", "gene_name": "UBE2K", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V0Z1W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1W7" } ] } ] }, { "uniprot_ac": "A0A8V0Z2L5", "gene_name": "TRIM63", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z2L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L5" } ] } ] }, { "uniprot_ac": "A0A8V0Z4C8", "gene_name": "MGRN1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z4C8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C8" } ] } ] }, { "uniprot_ac": "A0A8V0Z596", "gene_name": "STUB1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0Z596", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z596" } ] } ] }, { "uniprot_ac": "A0A8V0ZF21", "gene_name": "DTX3L", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZF21" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ49", "gene_name": "SMURF1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZJ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ49" } ] } ] }, { "uniprot_ac": "A0A8V0ZJV9", "gene_name": "MIB2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZJV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJV9" } ] } ] }, { "uniprot_ac": "A0A8V0ZKK3", "gene_name": "UBE3B", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" } ] } ] }, { "uniprot_ac": "A0A8V0ZKQ3", "gene_name": "RNF25", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZKQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ3" } ] } ] }, { "uniprot_ac": "A0A8V0ZL18", "gene_name": "HECTD2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZL18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL18" } ] } ] }, { "uniprot_ac": "A0A8V0ZM17", "gene_name": "UBR1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM17" } ] } ] }, { "uniprot_ac": "A0A8V0ZS27", "gene_name": "TRIP12", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZS27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS27" } ] } ] }, { "uniprot_ac": "A0A8V0ZSA3", "gene_name": "HERC4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZSA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSA3" } ] } ] }, { "uniprot_ac": "A0A8V0ZSH4", "gene_name": "RNF111", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZSH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSH4" } ] } ] }, { "uniprot_ac": "A0A8V0ZVX3", "gene_name": "NEDD4", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZVX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVX3" } ] } ] }, { "uniprot_ac": "A0A8V0ZW26", "gene_name": "ZNRF1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZW26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW26" } ] } ] }, { "uniprot_ac": "A0A8V0ZZH3", "gene_name": "ITCH", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V0ZZH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZH3" } ] } ] }, { "uniprot_ac": "A0A8V1A052", "gene_name": "UBE2E3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A052", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A052" } ] } ] }, { "uniprot_ac": "A0A8V1A0X2", "gene_name": "UBE3C", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A0X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0X2" } ] } ] }, { "uniprot_ac": "A0A8V1A0Z6", "gene_name": "UBE4A", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Z6" } ] } ] }, { "uniprot_ac": "A0A8V1A1I4", "gene_name": "UBE2Z", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1I4" } ] } ] }, { "uniprot_ac": "A0A8V1A1N8", "gene_name": "HERC1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1A1N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N8" } ] } ] }, { "uniprot_ac": "A0A8V1A233", "gene_name": "RNF220", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A233" } ] } ] }, { "uniprot_ac": "A0A8V1A2W7", "gene_name": "RNF41", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A2W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2W7" } ] } ] }, { "uniprot_ac": "A0A8V1A4H7", "gene_name": "UBE2L3", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A4H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4H7" } ] } ] }, { "uniprot_ac": "A0A8V1A5P4", "gene_name": "UBE2G2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "A0A8V1A5P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5P4" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A7T1", "gene_name": "RNF123", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A7T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7T1" } ] } ] }, { "uniprot_ac": "A0A8V1A9M0", "gene_name": "RNF34", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1A9M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9M0" } ] } ] }, { "uniprot_ac": "A0A8V1AC19", "gene_name": "UBA7", "activity": [ { "ec_number": "6.2.1.45", "activity": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] }, { "ec_number": "6.2.1.45", "activity": "", "evidence": [ { "id": "A0A8V1AC19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC19" } ] } ] }, { "uniprot_ac": "A0A8V1AC55", "gene_name": "SMURF2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "A0A8V1AC55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC55" } ] } ] }, { "uniprot_ac": "A0A8V1ACU3", "gene_name": "UBE2O", "activity": [ { "ec_number": "2.3.2.24", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E1 ubiquitin-activating enzyme]-L-cysteine + N(6)-monoubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] }, { "ec_number": "2.3.2.24", "activity": "", "evidence": [ { "id": "A0A8V1ACU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACU3" } ] } ] }, { "uniprot_ac": "A0A8V1AKB8", "gene_name": "TRIM32", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AKB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKB8" } ] } ] }, { "uniprot_ac": "A0A8V1AL09", "gene_name": "TRIM37", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AL09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL09" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "A0A8V1AML5", "gene_name": "TRIM50", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AML5" } ] } ] }, { "uniprot_ac": "A0A8V1AP69", "gene_name": "TRIM58", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1AP69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP69" } ] } ] }, { "uniprot_ac": "E1BZ35", "gene_name": "RNF182", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1BZ35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BZ35" } ] } ] }, { "uniprot_ac": "E1C3Q9", "gene_name": "SIAH2", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "E1C3Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C3Q9" } ] } ] }, { "uniprot_ac": "E1C656", "gene_name": "HACE1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C656", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C656" } ] } ] }, { "uniprot_ac": "E1C982", "gene_name": "AREL1", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "E1C982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C982" } ] } ] }, { "uniprot_ac": "F1NC08", "gene_name": "RNF138", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NC08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC08" } ] } ] }, { "uniprot_ac": "F1NL19", "gene_name": "CDC34", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "F1NL19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL19" } ] } ] }, { "uniprot_ac": "F1NL77", "gene_name": "CBLB", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NL77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NL77" } ] } ] }, { "uniprot_ac": "F1NRC6", "gene_name": "RLIM", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NRC6" } ] } ] }, { "uniprot_ac": "F1NTZ8", "gene_name": "HECW2", "activity": [ { "ec_number": "2.3.2.26", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] }, { "ec_number": "2.3.2.26", "activity": "", "evidence": [ { "id": "F1NTZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTZ8" } ] } ] }, { "uniprot_ac": "F1NVY8", "gene_name": "LNX1", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "F1NVY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVY8" } ] } ] }, { "uniprot_ac": "F1P2G0", "gene_name": "SIAH1", "activity": [ { 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"Q5ZKX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKX6" } ] } ] }, { "uniprot_ac": "R4GIV8", "gene_name": "UBE2R2", "activity": [ { "ec_number": "2.3.2.23", "activity": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] }, { "ec_number": "2.3.2.23", "activity": "", "evidence": [ { "id": "R4GIV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GIV8" } ] } ] }, { "uniprot_ac": "Z4YJC3", "gene_name": "TRIM71", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "Z4YJC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Z4YJC3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKK3" }, { "id": "PS50237", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50237" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HECT", "eco_id": "ECO_0000259", "start_pos": 704, "end_pos": 1070, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.26", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.26", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.26" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1046, "end_pos": 1048 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 519, "end_pos": 521 }, { "start_pos": 831, "end_pos": 833 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"Other" ] }, { "id": "A0A8V0ZKL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASAGPQCSNLGPRQEESFGLRTDTLPAQRERQRRVWCLTPQQQAKPIRTLERQRVNAHQDRSPQPSGIPLQHSCFLYPPALCPSHHYPSESTQPCPELCGSTLLYQRSCLRAKPYRFPFRSPQDTSSAPGSAMSSLLMEPCLPPALPEEHTGSGLKGSALSLGSACPQQASSSCRPALHSNSFLQPSSAKVPLLQSPGIKKLKNTPSFPIISWPRSRADGDCFPHSPAVQSSDWEQTSVSSLTPMPSSVTLRNERCSWPLGDTERKAHSLCETEPKISLTTAVQQLVGQTATCSGFGHEVKSSGLRNAGGLSNRDRSGHHIIAQLTPEETITPPNLEMGNHRLNGNSSLIGTDGAVVCTKRISVHLLASRASSPDRTSNCRLTSTLTLHGSEQGTGAEPPQLAAISEVATQMSSIQLEKKEKCAHTVLPKKPDVAAGELLLELSHPQGDVEEELPDGLDESCSLEEEEDSDSDASSVTGMSSNGSVALASRKCHECLAQPTEDQEKVLKPALVCSLFPNVPPTIYFSTRDERVEKLPWEQRKLLRWKMCTVTPNIVKQTISRSHFRVSKKSNDWLGCWGHHMKSPGFRAIREHQKLNHFPGSFQIGRKDRLWRNLLKMQTRCGKKEFNFFPQSFILPQDIKLLRKAWEEGASHQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLIDGRKFDLRIYVYVTCYDPLRVYLFKDGLVRFASCKYSSSMKSLSNKFVHLTNYSVNKKNTEYKSNLDETACQGHKWALKALWNYLTQKGVNSEAIWEKIKDIVIKTIIASEPYVNSLVKMYVRRPYCCHELFGFDIMLDENLKPWILEVNISPSLHSNSPLDVSIKGQMIRDLLNLAGFVLPSTDSIASRPQTRSDSTCSQGSALKEKPRPASECFTAEKLKKAYYLTQKIPDQDFYSSVLDILTPDDVRILVETEDEYSRRGQFERVFPTHISMRYLRFFEQPRYFNILVTQWELKYYLNKHKGLELLKKWCVKGYHTGAGTDLAQMWSLPKSFFLQKSRVQSNGFSKLELDRLGNLLSPNNGDLVRCLEPSPAQSLPLNKCTAGADQKPGGCLSDTALVL", "length": 1099, "header": "tr|A0A8V0ZKL0-1|A0A8V0ZKL0_CHICK Isoform 1 of Tubulin tyrosine ligase like 4 OS=Gallus gallus OX=9031 GN=TTLL4 PE=3 SV=1 CANONICAL=A0A8V0ZKL0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL0/entry#A0A8V0ZKL0-1", "sequence": { "sequence": "MASAGPQCSNLGPRQEESFGLRTDTLPAQRERQRRVWCLTPQQQAKPIRTLERQRVNAHQDRSPQPSGIPLQHSCFLYPPALCPSHHYPSESTQPCPELCGSTLLYQRSCLRAKPYRFPFRSPQDTSSAPGSAMSSLLMEPCLPPALPEEHTGSGLKGSALSLGSACPQQASSSCRPALHSNSFLQPSSAKVPLLQSPGIKKLKNTPSFPIISWPRSRADGDCFPHSPAVQSSDWEQTSVSSLTPMPSSVTLRNERCSWPLGDTERKAHSLCETEPKISLTTAVQQLVGQTATCSGFGHEVKSSGLRNAGGLSNRDRSGHHIIAQLTPEETITPPNLEMGNHRLNGNSSLIGTDGAVVCTKRISVHLLASRASSPDRTSNCRLTSTLTLHGSEQGTGAEPPQLAAISEVATQMSSIQLEKKEKCAHTVLPKKPDVAAGELLLELSHPQGDVEEELPDGLDESCSLEEEEDSDSDASSVTGMSSNGSVALASRKCHECLAQPTEDQEKVLKPALVCSLFPNVPPTIYFSTRDERVEKLPWEQRKLLRWKMCTVTPNIVKQTISRSHFRVSKKSNDWLGCWGHHMKSPGFRAIREHQKLNHFPGSFQIGRKDRLWRNLLKMQTRCGKKEFNFFPQSFILPQDIKLLRKAWEEGASHQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLIDGRKFDLRIYVYVTCYDPLRVYLFKDGLVRFASCKYSSSMKSLSNKFVHLTNYSVNKKNTEYKSNLDETACQGHKWALKALWNYLTQKGVNSEAIWEKIKDIVIKTIIASEPYVNSLVKMYVRRPYCCHELFGFDIMLDENLKPWILEVNISPSLHSNSPLDVSIKGQMIRDLLNLAGFVLPSTDSIASRPQTRSDSTCSQGSALKEKPRPASECFTAEKLKKAYYLTQKIPDQDFYSSVLDILTPDDVRILVETEDEYSRRGQFERVFPTHISMRYLRFFEQPRYFNILVTQWELKYYLNKHKGLELLKKWCVKGYHTGAGTDLAQMWSLPKSFFLQKSRVQSNGFSKLELDRLGNLLSPNNGDLVRCLEPSPAQSLPLNKCTAGADQKPGGCLSDTALVL", "length": 1099, "header": "tr|A0A8V0ZKL0-1|A0A8V0ZKL0_CHICK Isoform 1 of Tubulin tyrosine ligase like 4 OS=Gallus gallus OX=9031 GN=TTLL4 PE=3 SV=1 CANONICAL=A0A8V0ZKL0-1" }, "locus": { "chromosome": "7", "start_pos": 22068398, "end_pos": 22051448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052359.1", "url": "https://www.ensembl.org/id/ENSGALT00010052359.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031287.1", "url": "https://www.ensembl.org/id/ENSGALP00010031287.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tubulin-glutamic acid ligase activity", "id": "GO:0070740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070740", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKL0" } 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZKM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHCFLGREILSFFCLTVRKMWLKFILAILLLHAAAGKEPEPQYVLMVPAVLQSDSPSQVCLQFFNLNQTISVRVVLEYDTINTTIFEKNTTTSNGLQCLNFMIPPVTSVSLAFISFTAKGTTFDLKERRSVMIWNMESFVFVQTDKPIYKPGQSVMFRVVALDFNFKPVQEMYPLIAVQDPQNNRIFQWQNVTSEINIVQIEFPLTEEPILGNYKIIVTKKSGERTSHSFLVEEYVLPKFDVTVTAPGSLTVMDSELTVKICAVYTYGQPVEGKVQLSVCRDFDSYGRCKKSPVCQSFTKDLDTDGCLSHILSSKVFELNRIGYKRNLDVKAIVTEKGTGLQLTATQSISITQVMSSLQFENVDHHYRRGIPYFGQIKLVDKDNSPISNKVIQLFVNNKNTHNFTTDINGIAPFSIDTSKIFDPELSLKALYKTSDQCHSEGWIEPSYPDASLSVQRLYSWTSSFVRIEPLWKDMSCGQKRMITVYYILNTEGYEHINIVNFYYVGMAKGKIVLTGEIKVNIQADQNGTFMIPLVVNEKMAPALRLLVYMLHPAKELVADSVRFSIEKCFKNKVQLQFSEKQMLTTSNVSLVIEAAANSFCAVRAVDKSMLLLKSETELSAETIYNLHPIQDLQGYIFNGLNLEDDPQDPCVSSDDIFHKGLYYRPLTSGLGPDVYQFLRDMGMKFFTNSKIRQPTVCTRETVRPPSYFLNAGFTASTHHVKLSAEVAREERGKRHILETIREFFPETWIWDIILINSTGKASVSYTIPDTITEWKASAFCVEELAGFGMSVPATLTAFQPFFVDLTLPYSIIHGEDFLLRANVFNYLNHCIKINVLLLESLDYQAKLISPEDDGCVCAKIRKSYVWNIFPKGTGDVLFSITAETNDDEACEEEALRNIRIDYRDTQIRALLVEPEGIRREETQNFLICMKDDVISQDVAIDLPTNVVEGSPRPSFSVVGDIMGTAIQNVHQLLQMPFGNGEQNMVLFAPNIYVLDYLDKTRQLSEDVKSKTIGYLVSGYQKQLSYKHPDGSYSTFGIRDKEGNTWLTAFVYKSFAEASRFIYIDDNVQAQTLIWLARKQKTDGCFQSTGILVNNAMKGGVENELSLSAYITIALLEAGHSMSHTVIRNAFYCLETASEKNITDIYTQALVAYAFCLAGKAEICESFLRELQKSAKEVDGSKYWEQNQRSAPEKSHLLDHVQSTDVEITSYVLLALLYKPNRSQEDLTKASAIVQWIIRQQNSYGGFASMQDTVVALQALAAYGAATYNSVTQNVIKINSKNTFEKVFTVNNENRLLLQQTPLPQVPGKYSLTVNGTGCVLIQTALRYNIHLPEGAFGFSLSVQTSNASCPRDQPGKFDIVLISSYTGKRSSSNMVIIDVKMLSGFVPVKSSLDQLIDDHTVMQVEYKKNHVLLYLGNILQKRRKEVTFSVEQDFVVTHPKPAPVQIYDYYETEEYAVAEYMSLCRGVVEEMG", "length": 1473, "header": "tr|A0A8V0ZKM2-1|A0A8V0ZKM2_CHICK Isoform 1 of Ovostatin OS=Gallus gallus OX=9031 GN=OVST PE=1 SV=1 CANONICAL=A0A8V0ZKM2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM2/entry#A0A8V0ZKM2-1", "sequence": { "sequence": "MHCFLGREILSFFCLTVRKMWLKFILAILLLHAAAGKEPEPQYVLMVPAVLQSDSPSQVCLQFFNLNQTISVRVVLEYDTINTTIFEKNTTTSNGLQCLNFMIPPVTSVSLAFISFTAKGTTFDLKERRSVMIWNMESFVFVQTDKPIYKPGQSVMFRVVALDFNFKPVQEMYPLIAVQDPQNNRIFQWQNVTSEINIVQIEFPLTEEPILGNYKIIVTKKSGERTSHSFLVEEYVLPKFDVTVTAPGSLTVMDSELTVKICAVYTYGQPVEGKVQLSVCRDFDSYGRCKKSPVCQSFTKDLDTDGCLSHILSSKVFELNRIGYKRNLDVKAIVTEKGTGLQLTATQSISITQVMSSLQFENVDHHYRRGIPYFGQIKLVDKDNSPISNKVIQLFVNNKNTHNFTTDINGIAPFSIDTSKIFDPELSLKALYKTSDQCHSEGWIEPSYPDASLSVQRLYSWTSSFVRIEPLWKDMSCGQKRMITVYYILNTEGYEHINIVNFYYVGMAKGKIVLTGEIKVNIQADQNGTFMIPLVVNEKMAPALRLLVYMLHPAKELVADSVRFSIEKCFKNKVQLQFSEKQMLTTSNVSLVIEAAANSFCAVRAVDKSMLLLKSETELSAETIYNLHPIQDLQGYIFNGLNLEDDPQDPCVSSDDIFHKGLYYRPLTSGLGPDVYQFLRDMGMKFFTNSKIRQPTVCTRETVRPPSYFLNAGFTASTHHVKLSAEVAREERGKRHILETIREFFPETWIWDIILINSTGKASVSYTIPDTITEWKASAFCVEELAGFGMSVPATLTAFQPFFVDLTLPYSIIHGEDFLLRANVFNYLNHCIKINVLLLESLDYQAKLISPEDDGCVCAKIRKSYVWNIFPKGTGDVLFSITAETNDDEACEEEALRNIRIDYRDTQIRALLVEPEGIRREETQNFLICMKDDVISQDVAIDLPTNVVEGSPRPSFSVVGDIMGTAIQNVHQLLQMPFGNGEQNMVLFAPNIYVLDYLDKTRQLSEDVKSKTIGYLVSGYQKQLSYKHPDGSYSTFGIRDKEGNTWLTAFVYKSFAEASRFIYIDDNVQAQTLIWLARKQKTDGCFQSTGILVNNAMKGGVENELSLSAYITIALLEAGHSMSHTVIRNAFYCLETASEKNITDIYTQALVAYAFCLAGKAEICESFLRELQKSAKEVDGSKYWEQNQRSAPEKSHLLDHVQSTDVEITSYVLLALLYKPNRSQEDLTKASAIVQWIIRQQNSYGGFASMQDTVVALQALAAYGAATYNSVTQNVIKINSKNTFEKVFTVNNENRLLLQQTPLPQVPGKYSLTVNGTGCVLIQTALRYNIHLPEGAFGFSLSVQTSNASCPRDQPGKFDIVLISSYTGKRSSSNMVIIDVKMLSGFVPVKSSLDQLIDDHTVMQVEYKKNHVLLYLGNILQKRRKEVTFSVEQDFVVTHPKPAPVQIYDYYETEEYAVAEYMSLCRGVVEEMG", "length": 1473, "header": "tr|A0A8V0ZKM2-1|A0A8V0ZKM2_CHICK Isoform 1 of Ovostatin OS=Gallus gallus OX=9031 GN=OVST PE=1 SV=1 CANONICAL=A0A8V0ZKM2-1" }, "locus": { "chromosome": "1", "start_pos": 76316756, "end_pos": 76282591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056065.1", "url": "https://www.ensembl.org/id/ENSGALT00010056065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033918.1", "url": "https://www.ensembl.org/id/ENSGALP00010033918.1" } ] } }, { "isoform_ac": "A0A8V0ZKN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM2/entry#A0A8V0ZKN1-1", "sequence": { "sequence": "MHCFLGREILSFFCLTVRKMWLKFILAILLLHAAAGKEPEPQYVLMVPAVLQSDSPSQVCLQFFNLNQTISVRVVLEYDTINTTIFEKNTTTSNGLQCLNFMIPPVTSVSLAFISFTAKGTTFDLKERRSVMIWNMESFVFVQTDKPIYKPGQSVMFRVVALDFNFKPVQEMDPQNNRIFQWQNVTSEINIVQIEFPLTEEPILGNYKIIVTKKSGERTSHSFLVEEYVLPKFDVTVTAPGSLTVMDSELTVKICAVYTYGQPVEGKVQLSVCRDFDSYGRCKKSPVCQSFTKDLDTDGCLSHILSSKVFELNRIGYKRNLDVKAIVTEKGTATQSISITQVMSSLQFENVDHHYRRGIPYFGQIKLVDKDNSPISNKVIQLFVNNKNTHNFTTDINGIAPFSIDTSKIFDPELSLKALYKTSDQCHSEGWIEPSYPDASLSVQRLYSWTSSFVRIEPLWKDMSCGQKRMITVYYILNTEGYEHINIVNFYYVGMAKGKIVLTGEIKVNIQADQNGTFMIPLVVNEKMAPALRLLVYMLHPAKELVADSVRFSIEKCFKNKVQLQFSEKQMLTTSNVSLVIEAAANSFCAVRAVDKSMLLLKSETELSAETIYNLHPIQDLQGYIFNGLNLEDDPQDPCVSSDDIFHKGLYYRPLTSGLGPDVYQFLRDMGMKFFTNSKIRQPTVCTRETVRPPSYFLNAGFTASTHHVKLSAEVAREERGKRHILETIREFFPETWIWDIILINSTGKASVSYTIPDTITEWKASAFCVEELAGFGMSVPATLTAFQPFFVDLTLPYSIIHGEDFLLRANVFNYLNHCIKINVLLLESLDYQAKLISPEDDGCVCAKIRKSYVWNIFPKGTGDVLFSITAETNDDEACEEEALRNIRIDYRDTQIRALLVEPEGIRREETQNFLICMKDDVISQDVAIDLPTNVVEGSPRPSFSVVGDIMGTAIQNVHQLLQMPFGNGEQNMVLFAPNIYVLDYLDKTRQLSEDVKSKTIGYLVSGYQKQLSYKHPDGSYSTFGIRDKEGNTWLTAFVYKSFAEASRFIYIDDNVQAQTLIWLARKQKTDGCFQSTGILVNNAMKGGVENELSLSAYITIALLEAGHSMSHTVIRNAFYCLETASEKNITDIYTQALVAYAFCLAGKAEICESFLRELQKSAKEVDGSKYWEQNQRSAPEKSHLLDHVQSTDVEITSYVLLALLYKPNRSQEDLTKASAIVQWIIRQQNSYGGFASMQDTVVALQALAAYGAATYNSVTQNVIKINSKNTFEKVFTVNNENRLLLQQTPLPQVPGKYSLTVNGTGCVLIQTALRYNIHLPEGAFGFSLSVQTSNASCPRDQPGKFDIVLIKCSVYSVLLKLIDDHTVMQVEYKKNHVLLYLGNILQKRRKEVTFSVEQDFVVTHPKPAPVQIYDYYETEEYAVAEYMSLCRGVVEEMG", "length": 1439, "header": "tr|A0A8V0ZKN1-1|A0A8V0ZKN1_CHICK Computationally mapped isoform of Ovostatin OS=Gallus gallus OX=9031 GN=OVST PE=1 SV=1 CANONICAL=A0A8V0ZKM2-1" }, "locus": { "chromosome": "1", "start_pos": 76316756, "end_pos": 76282591, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056079.1", "url": "https://www.ensembl.org/id/ENSGALT00010056079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033928.1", "url": "https://www.ensembl.org/id/ENSGALP00010033928.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1141, "end_pos": 1143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1221, "end_pos": 1223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1315, "end_pos": 1317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1347, "end_pos": 1349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 757, "end_pos": 759, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM2" }, { "id": "SM01360", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01360" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-2-macroglobulin", "eco_id": "ECO_0000259", "start_pos": 748, "end_pos": 838, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZKM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM2" }, { "id": "SM01359", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01359" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-2-macroglobulin bait region", "eco_id": "ECO_0000259", "start_pos": 466, "end_pos": 613, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZKM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM2" }, { "id": "SM01361", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01361" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-macroglobulin receptor-binding", "eco_id": "ECO_0000259", "start_pos": 1373, "end_pos": 1461, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1141, "end_pos": 1143 }, { "start_pos": 1221, "end_pos": 1223 }, { "start_pos": 1315, "end_pos": 1317 }, { "start_pos": 1347, "end_pos": 1349 }, { "start_pos": 191, "end_pos": 193 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 527, "end_pos": 529 }, { "start_pos": 588, "end_pos": 590 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 757, "end_pos": 759 }, { "start_pos": 82, "end_pos": 84 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKM4-1", "uniprot_ac": "A0A8V0ZKM4", "uniprot_id": "A0A8V0ZKM4_CHICK", "mass": { "chemical_mass": 26813.0, "monoisotopic_mass": 26813.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Tubulin monoglycylase TTLL3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM4", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZKM4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKM4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR051437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45870", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45870", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45870:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45870:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRIEKVANAAAGAPGKVQRVRAVCSRPWLCPEQLKLAKLQVEKAIKEKKIFMVQGRYPVIRRLLRARGWVERKAPRRAQQEEAGGGDAELSTAQHGVQPSLESLCSMWLPSEEEEEEEEEEEQMDKDDPDGLHNLMSRLVQDQVPYFIWSSRCSAAERCVLRPDQMVNHYARGGCLTTKEGLCLTLRNLPWFDQADPDTFFPRCYRLGAVDERQAFIGELGVGVVRAHGSHIPSTALG", "length": 238, "header": "tr|A0A8V0ZKM4-1|A0A8V0ZKM4_CHICK Isoform 1 of Tubulin monoglycylase TTLL3 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZKM4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM4/entry#A0A8V0ZKM4-1", "sequence": { "sequence": "MRIEKVANAAAGAPGKVQRVRAVCSRPWLCPEQLKLAKLQVEKAIKEKKIFMVQGRYPVIRRLLRARGWVERKAPRRAQQEEAGGGDAELSTAQHGVQPSLESLCSMWLPSEEEEEEEEEEEQMDKDDPDGLHNLMSRLVQDQVPYFIWSSRCSAAERCVLRPDQMVNHYARGGCLTTKEGLCLTLRNLPWFDQADPDTFFPRCYRLGAVDERQAFIGELGVGVVRAHGSHIPSTALG", "length": 238, "header": "tr|A0A8V0ZKM4-1|A0A8V0ZKM4_CHICK Isoform 1 of Tubulin monoglycylase TTLL3 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZKM4-1" }, "locus": { "chromosome": "12", "start_pos": 11668810, "end_pos": 11667711, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052442.1", "url": "https://www.ensembl.org/id/ENSGALT00010052442.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031349.1", "url": "https://www.ensembl.org/id/ENSGALP00010031349.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM4" } ], "pmid": "" }, { "name": "acid-amino acid ligase activity", "id": "GO:0016881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016881", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM4" } ], "pmid": "" }, { "name": "catalytic activity, acting on a protein", "id": "GO:0140096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKQ4-1", "uniprot_ac": "A0A8V0ZKQ4", "uniprot_id": "A0A8V0ZKQ4_CHICK", "mass": { "chemical_mass": 90470.0, "monoisotopic_mass": 90470.0 }, "refseq": {}, "gene_names": [ { "name": "RAD54L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4" } ] } ], "protein_names": [ { "name": "DNA repair and recombination protein RAD54-like", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Multifunctional ATPase that plays a role in homologous recombination (HR) which is a major pathway for repairing DNA double-strand breaks (DSBs), single-stranded DNA (ssDNA) gaps, and stalled or collapsed replication forks. Acts as a molecular motor during the homology search and guides RAD51 ssDNA along a donor dsDNA thereby changing the homology search from the diffusion-based mechanism to a motor-guided mechanism. Also plays an essential role in RAD51-mediated synaptic complex formation which consists of three strands encased in a protein filament formed once homology is recognized. Once DNA strand exchange occured, dissociates RAD51 from nucleoprotein filaments formed on dsDNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4#function" }, { "database": "UniProtKB", "id": "ARBA00094353", "url": "https://www.uniprot.org/uniprotkb/ARBA00094353#function" }, { "database": "UniProtKB", "id": "A0A8V0ZSY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAD54L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4", "locus": { "chromosome": "8", "start_pos": 21279424, "end_pos": 21259049, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023052", "url": "https://www.ensembl.org/id/ENSGALG00010023052" } ] } } ], "crossref": [ { "id": "A0A8V0ZKQ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKQ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18067", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18067", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKQ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSY7", "url": "https://www.orthodb.org/?gene=A0A8V0ZSY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45629", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45629", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45629:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45629:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZKQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFDALGARLATPGALPEGRGERGGAEPPALFAPSERRPRPVARLPAHLALCRPLPPPFREAMRRSLAPSQLAKRKAGGEEEDGEWRPPATQKRQKAGSEAESADCYRSPFRKPLTQLTNRPLCLDSSQHEAFIRSILSKPFKVPIPNYKGPTGLRALGIKRAGLRSPLHDPFEEGALVLYEPPLLSAHEQLKIDKDKVPVHVVVDPVLSRVLRPHQREGVKFLWDCVTSRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPDCKPEIEKAMVVSPSSLVRNWYNEVEKWLGGRIQPLAIDGGSKEEIDRKLVGFMNQRGLRVPSPILIISYETFRLHAEALQKGSVGLVICDEGHRLKNSENQTYQALNSLNTPRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAQEFKRHFELPILKGRDADASEAERQKGEERLKELISIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQAELYKNFLKQAKPVEELKEGKINVSSLSSITSLKKLCNHPALIYDKCVEEEEGFMGALDLFPAGYSTKSVEPQLSGKMLVLDYILAVTKSTSNDKVVLVSNYTQTLDLFEKLCRNRRYLYVRLDGTMSIKKRAKVVERFNSPSSPEFIFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSTGTIEEKIFQRQTHKKALSSCVVDEEQDVERHFSLGELKELFSLNETTISDTHDKIKCRRCVNGHQVRPPPEGSDCTSDLSQWNHCADKRGLQDSVLKAAWDAAVTFTFHHHSHEEQRGIP", "length": 804, "header": "tr|A0A8V0ZKQ4-1|A0A8V0ZKQ4_CHICK Isoform 1 of DNA repair and recombination protein RAD54-like OS=Gallus gallus OX=9031 GN=RAD54L PE=4 SV=1 CANONICAL=A0A8V0ZKQ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4/entry#A0A8V0ZKQ4-1", "sequence": { "sequence": "MRFDALGARLATPGALPEGRGERGGAEPPALFAPSERRPRPVARLPAHLALCRPLPPPFREAMRRSLAPSQLAKRKAGGEEEDGEWRPPATQKRQKAGSEAESADCYRSPFRKPLTQLTNRPLCLDSSQHEAFIRSILSKPFKVPIPNYKGPTGLRALGIKRAGLRSPLHDPFEEGALVLYEPPLLSAHEQLKIDKDKVPVHVVVDPVLSRVLRPHQREGVKFLWDCVTSRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPDCKPEIEKAMVVSPSSLVRNWYNEVEKWLGGRIQPLAIDGGSKEEIDRKLVGFMNQRGLRVPSPILIISYETFRLHAEALQKGSVGLVICDEGHRLKNSENQTYQALNSLNTPRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAQEFKRHFELPILKGRDADASEAERQKGEERLKELISIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQAELYKNFLKQAKPVEELKEGKINVSSLSSITSLKKLCNHPALIYDKCVEEEEGFMGALDLFPAGYSTKSVEPQLSGKMLVLDYILAVTKSTSNDKVVLVSNYTQTLDLFEKLCRNRRYLYVRLDGTMSIKKRAKVVERFNSPSSPEFIFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSTGTIEEKIFQRQTHKKALSSCVVDEEQDVERHFSLGELKELFSLNETTISDTHDKIKCRRCVNGHQVRPPPEGSDCTSDLSQWNHCADKRGLQDSVLKAAWDAAVTFTFHHHSHEEQRGIP", "length": 804, "header": "tr|A0A8V0ZKQ4-1|A0A8V0ZKQ4_CHICK Isoform 1 of DNA repair and recombination protein RAD54-like OS=Gallus gallus OX=9031 GN=RAD54L PE=4 SV=1 CANONICAL=A0A8V0ZKQ4-1" }, "locus": { "chromosome": "8", "start_pos": 21277041, "end_pos": 21259248, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056127.1", "url": "https://www.ensembl.org/id/ENSGALT00010056127.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033954.1", "url": "https://www.ensembl.org/id/ENSGALP00010033954.1" } ] } }, { "isoform_ac": "A0A8V0ZSY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4/entry#A0A8V0ZSY7-1", "sequence": { "sequence": "MRRSLAPSQLAKRKAGGEEEDGEWRPPAEAFIRSILSKPFKVPIPNYKGPTGLRALGIKRAGLRSPLHDPFEEGALVLYEPPLLSAHEQLKIDKDKVPVHVVVDPVLSRVLRPHQREGVKFLWDCVTSRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPDCKPEIEKAMVVSPSSLVRNWYNEVEKWLGGRIQPLAIDGGSKEEIDRKLVGFMNQRGLRVPSPILIISYETFRLHAEALQKGSVGLVICDEGHRLKNSENQTYQALNSLNTPRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAQEFKRHFELPILKGRDADASEAERQKGEERLKELISIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQAELYKNFLKQAKPVEELKEGKINVSSLSSITSLKKLCNHPALIYDKCVEEEEGFMGALDLFPAGYSTKSVEPQLSGKMLVLDYILAVTKSTSNDKVVLVSNYTQTLDLFEKLCRNRRYLYVRLDGTMSIKKRAKVVERFNSPSSPEFIFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSTGTIEEKIFQRQTHKKALSSCVVDEEQDVERHFSLGELKELFSLNETTISDTHDKIKCRRCVNGHQVRPPPEGSDCTSDLSQWNHCADKRGLQDSVLKAAWDAAVTFTFHHHSHEEQRGIP", "length": 702, "header": "tr|A0A8V0ZSY7-1|A0A8V0ZKQ4_CHICK Computationally mapped isoform of DNA repair and recombination protein RAD54-like OS=Gallus gallus OX=9031 GN=RAD54L PE=4 SV=1 CANONICAL=A0A8V0ZKQ4-1" }, "locus": { "chromosome": "8", "start_pos": 21277041, "end_pos": 21259434, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056121.1", "url": "https://www.ensembl.org/id/ENSGALT00010056121.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033948.1", "url": "https://www.ensembl.org/id/ENSGALP00010033948.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 12, "start_aa": "Thr", "end_pos": 12, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr12", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4" } ], "pmid": "" }, { "name": "ATP-dependent DNA/DNA annealing activity", "id": "GO:0036310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036310", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4" } ], "pmid": "" }, { "name": "DNA translocase activity", "id": "GO:0015616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015616", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ4" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", 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}, { "uniprot_ac": "A0A1D5PVS9", "gene_name": "ENTPD3", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A1D5PVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PVS9" } ] } ] }, { "uniprot_ac": "A0A3S5ZPN3", "gene_name": "DDX5", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A3S5ZPN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3S5ZPN3" } ] } ] }, { "uniprot_ac": "A0A8V0X600", "gene_name": "DDX43", 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"ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0XLC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLC7" } ] } ] }, { "uniprot_ac": "A0A8V0XMP8", "gene_name": "ZGRF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0XMP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMP8" } ] } ] }, { "uniprot_ac": "A0A8V0XT73", "gene_name": "FBXO18", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XT73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XT73" } ] } ] }, { "uniprot_ac": "A0A8V0XX13", "gene_name": "LOC101748706", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0XX13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XX13" } ] } ] }, { "uniprot_ac": "A0A8V0XZB8", "gene_name": "DHX34", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0XZB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XZB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y005", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", 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5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": 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"ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": 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} ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V0ZNW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNW3" } ] } ] }, { "uniprot_ac": "A0A8V0ZPM1", "gene_name": "LOC121108097", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZPM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM1" } ] } ] }, { "uniprot_ac": "A0A8V0ZPN6", "gene_name": "INO80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8V0ZPN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZR10", "gene_name": "PIF1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of 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"id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUR5", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": 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"activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": 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"evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": "A0A8V1A8Y2", "gene_name": "ENTPD8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1A8Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Y2" } ] } ] }, { "uniprot_ac": "A0A8V1ACD8", "gene_name": "NSF", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ACD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACD8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V1ACD8", "database": 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} ] } ] }, { "uniprot_ac": "A0A8V1AJY9", "gene_name": "DDX31", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AJY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJY9" } ] } ] }, { "uniprot_ac": "A0A8V1AKU6", "gene_name": "HELZ", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AKU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKU6" } ] } ] }, { "uniprot_ac": "A0A8V1AL41", "gene_name": "DHX33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = 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"activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { "uniprot_ac": "F1NA92", "gene_name": "CLPX", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "F1NA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA92" } ] } ] }, { "uniprot_ac": "F1ND48", "gene_name": "FBH1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1ND48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1ND48" } ] } ] }, { "uniprot_ac": "F1NFJ0", "gene_name": 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"id": "F1P5C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P5C0" } ] } ] }, { "uniprot_ac": "I0IUP3", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP3" } ] } ] }, { "uniprot_ac": "I0IUP4", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "I0IUP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I0IUP4" } ] } ] }, { "uniprot_ac": "O12944", "gene_name": "RAD54L", "activity": [ { 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] } ] }, { "uniprot_ac": "Q5ZHZ0", "gene_name": "DDX39B", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZHZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHZ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZHZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHZ0" } ] } ] }, { "uniprot_ac": "Q5ZI74", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZI74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI74" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZI74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI74" } ] } ] }, { "uniprot_ac": "Q5ZIW1", "gene_name": "TWNK", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKQ8-1", "uniprot_ac": "A0A8V0ZKQ8", "uniprot_id": "A0A8V0ZKQ8_CHICK", "mass": { "chemical_mass": 34780.0, "monoisotopic_mass": 34780.0 }, "refseq": { "ac": "NP_001264495", "name": "N-acetylglucosamine-1-phosphotransferase subunit gamma precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264495" }, "gene_names": [ { "name": "GNPTG", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ8" } ] }, { "name": "GNPTG", "type": "synonym", "evidence": [ { "id": "NP_001264495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264495" } ] } ], "protein_names": [ { "name": "N-acetylglucosamine-1-phosphotransferase subunit gamma", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ8/entry#names_and_taxonomy" } ] }, { "name": "GlcNAc-1-phosphotransferase subunit gamma", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ8/entry#names_and_taxonomy" } ] }, { "name": "N-acetylglucosamine-1-phosphotransferase subunit gamma precursor", "type": "synonym", "evidence": [ { "id": "NP_001264495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264495" } ] }, { "name": "N-acetylglucosamine-1-phosphotransferase, gamma subunit", "type": "synonym", "evidence": [ { "id": "NP_001264495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264495" } ] }, { "name": "UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01003308.1, HAEK01000015.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HAEL01003308.1, BU124403.1, CF254066.1, JAENSK010000257.1, BU125349.1, BX934921.1, BU347476.1, DN928417.1 and BU233846.1. On Nov 9, 2021 this sequence version replaced NP_001264495.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264495" } ] }, { "annotation": "Non-catalytic subunit of the N-acetylglucosamine-1-phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine-1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ8#function" }, { "database": "UniProtKB", "id": "ARBA00055725", "url": "https://www.uniprot.org/uniprotkb/ARBA00055725#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GNPTG", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ8", "locus": { "chromosome": "14", "start_pos": 7443277, "end_pos": 7433280, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020433", "url": "https://www.ensembl.org/id/ENSGALG00010020433" } ] } } ], "crossref": [ { "id": "A0A8V0ZKQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "416591", "url": "https://www.ncbi.nlm.nih.gov/gene/416591", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044865", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZKQ8/entry#A0A8V0ZKQ8-1", "sequence": { "sequence": "MAAARLLLAVFVGAALGVLASAGKMKIVEEPNTFGLNNPFLPQTNRLQPKMPPSAISGPVHLFRLAGKCFSFVESTYKYEFCPFHNVTQHEQTFRWNAYSGILGIWHEWEIDNNTFVGMWMREGDSCETKSRQTKVHLVCGKSNKLAYVSEPSTCVYSLTFETPLVCHPHSLLVYPTLTEALQRKWDEAEQSLYDQLITEQGYKKILKEIFEEAGLLKATEEKEAEKQNMKTSLQFETVDKCNKEYKKLSEEIKVLKDLLNQHNIAYQRSSAENTSVEHVNHKWATAETTVLNGSTNAERLHGDAGI", "length": 307, "header": "tr|A0A8V0ZKQ8-1|A0A8V0ZKQ8_CHICK Isoform 1 of N-acetylglucosamine-1-phosphotransferase subunit gamma OS=Gallus gallus OX=9031 GN=GNPTG PE=4 SV=1 CANONICAL=A0A8V0ZKQ8-1" }, "locus": { "chromosome": "14", "start_pos": 7441692, "end_pos": 7433284, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049403.1", "url": "https://www.ensembl.org/id/ENSGALT00010049403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029200.1", "url": "https://www.ensembl.org/id/ENSGALP00010029200.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416591", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416591", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3HBX0-1", "protein_name": "N-acetylglucosamine-1-phosphotransferase subunit gamma", "gene_name": "Gnptg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVRVAGFLMLLGLAARGPVPACAGKMKVVEEPNTFGLNNPFLPQANRLQPKREPSPVSGPLHLFRLAGKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSGILGIWHEWEITNNTFKGMWMTDGDSCHSRSRQSKVELTCGKINRLAHVSEPSTCVYALTFETPLVCHPHSLLVYPTLPEALQQRWDQMEQDLADELITLQGYGKLLRVLFEDAGYLKAPGETHPTQQQAGGSQGLGLETLDNCRKAHSELSQEVQRLTSLLDQHGIPHSQPTETTHSEHLGQRLPIGVTSEQLRGDPGLRGNIL", "length": 307 }, "evidence": [ { "id": "A0A8V0ZKQ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZKQ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6S5C2-1", "protein_name": "N-acetylglucosamine-1-phosphotransferase subunit gamma", "gene_name": "Gnptg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGRLAGFLMLLGLASQGPAPAYAGKMKVVEEPNTFGLNNPFLPQASRLQPKREPSAVSGPLHLFRLAGKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSGILGIWHEWEIINNTFKGMWMTDGDSCHSRSRQSKVELTCGKINRLAHVSEPSTCVYALTFETPLVCHPHSLLVYPTLSEALQQRWDQVEQDLADELITPQGYEKLLRVLFEDAGYLKVPGETHPTQLAGGSKGLGLETLDNCRKAHAELSQEVQRLTSLLQQHGIPHTQPTETTHSQHLGQQLPIGAIAAEHLRSDPGLRGNIL", "length": 307 }, "evidence": [ { "id": "A0A8V0ZKQ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZKQ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UJJ9-1", "protein_name": "N-acetylglucosamine-1-phosphotransferase subunit gamma", "gene_name": "GNPTG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGLARLLLLLGLSAGGPAPAGAAKMKVVEEPNAFGVNNPFLPQASRLQAKRDPSPVSGPVHLFRLSGKCFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSGILGIWHEWEIANNTFTGMWMRDGDACRSRSRQSKVELACGKSNRLAHVSEPSTCVYALTFETPLVCHPHALLVYPTLPEALQRQWDQVEQDLADELITPQGHEKLLRTLFEDAGYLKTPEENEPTQLEGGPDSLGFETLENCRKAHKELSKEIKRLKGLLTQHGIPYTRPTETSNLEHLGHETPRAKSPEQLRGDPGLRGSL", "length": 305 }, "evidence": [ { "id": "A0A8V0ZKQ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZKQ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ8" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate phosphorylation", "id": "GO:0046835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046835", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKQ8", "database": "UniProtKB", 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9/entry#names_and_taxonomy" } ] }, { "name": "Rod photoreceptor arrestin", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SAG", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9", "locus": { "chromosome": "9", "start_pos": 843886, "end_pos": 825155, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023056", "url": "https://www.ensembl.org/id/ENSGALG00010023056" } ] } } ], "crossref": [ 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}, { "id": "PTHR11792", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11792", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11792:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11792:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00339", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00339", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2514859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2514859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCPESQKTGKNADSSPKQVIFKKSTRDKALTIYLGKRDFIDNIGSVEPVDGVVLVDPAMIKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLFFSRVQVYPPENRPESLSHLQESLLKKLGKNAYPFYFTFPDYLPCSVCLQPSPRDVDKSCGVDFEVKAFSTENLEERIHKRNSARLLIRKVQFAPEEPGPQPCAETTWQFFMSNKPLHLKACLSKEVYYHGEPIPVTVMVTNSTEKTVKKIKVQVEQVANVVLYSSDFYTKVVAAEEAPEKVQPNSSLTTTLTVLPLLANNRQTREIALDGKLKDEDTNLASSTIIKDGIDKTVMGILVSYKVRVKLTVSGLLGDFTSSEVSTELPFRLMHPKPEEKNPAGCAEYTFQGILLASCNAAITAVWSAKILSKEHKHQRFIFRQG", "length": 414, "header": "tr|A0A8V0ZKQ9-1|A0A8V0ZKQ9_CHICK Isoform 1 of S-arrestin OS=Gallus gallus OX=9031 GN=SAG PE=3 SV=1 CANONICAL=A0A8V0ZKQ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9/entry#A0A8V0ZKQ9-1", "sequence": { "sequence": "MSCPESQKTGKNADSSPKQVIFKKSTRDKALTIYLGKRDFIDNIGSVEPVDGVVLVDPAMIKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLFFSRVQVYPPENRPESLSHLQESLLKKLGKNAYPFYFTFPDYLPCSVCLQPSPRDVDKSCGVDFEVKAFSTENLEERIHKRNSARLLIRKVQFAPEEPGPQPCAETTWQFFMSNKPLHLKACLSKEVYYHGEPIPVTVMVTNSTEKTVKKIKVQVEQVANVVLYSSDFYTKVVAAEEAPEKVQPNSSLTTTLTVLPLLANNRQTREIALDGKLKDEDTNLASSTIIKDGIDKTVMGILVSYKVRVKLTVSGLLGDFTSSEVSTELPFRLMHPKPEEKNPAGCAEYTFQGILLASCNAAITAVWSAKILSKEHKHQRFIFRQG", "length": 414, "header": "tr|A0A8V0ZKQ9-1|A0A8V0ZKQ9_CHICK Isoform 1 of S-arrestin OS=Gallus gallus OX=9031 GN=SAG PE=3 SV=1 CANONICAL=A0A8V0ZKQ9-1" }, "locus": { "chromosome": "9", "start_pos": 841033, "end_pos": 827770, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056135.1", "url": "https://www.ensembl.org/id/ENSGALT00010056135.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033959.1", "url": "https://www.ensembl.org/id/ENSGALP00010033959.1" } ] } }, { "isoform_ac": "A0A8V0ZR36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9/entry#A0A8V0ZR36-1", "sequence": { "sequence": "MSCPESQKTGKNADSSPKQVIFKKSTRDKALTIYLGKRDFIDNIGSVEPVDGVVLVDPAMIKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLFFSRVQVYPPENRPESLSHLQESLLKKLGKNAYPFYFTFPDYLPCSVCLQPSPRDVDKSCGVDFEVKAFSTENLEERIHKRNSARLLIRKVQFAPEEPGPQPCAETTWQFFMSNKPLHLKACLSKEVYYHGEPIPVTVMVTNSTEKTVKKIKVQVEQVANVVLYSSDFYTKVVAAEEAPEKVQPNSSLTTTLTVLPLLANNRQTREIALDGKLKDEDTNLASSTIIKDGIDKTVMGILVSYKVRVKLTVSGLLGDFTSSEVSTELPFRLMHPKPEEKNPAVMQRWYLRSLLANS", "length": 386, "header": "tr|A0A8V0ZR36-1|A0A8V0ZR36_CHICK Computationally mapped isoform of S-arrestin OS=Gallus gallus OX=9031 GN=SAG PE=3 SV=1 CANONICAL=A0A8V0ZKQ9-1" }, "locus": { "chromosome": "9", "start_pos": 842182, "end_pos": 827770, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056148.1", "url": "https://www.ensembl.org/id/ENSGALT00010056148.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033971.1", "url": "https://www.ensembl.org/id/ENSGALP00010033971.1" } ] } }, { "isoform_ac": "A0A8V0ZU02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9/entry#A0A8V0ZU02-1", "sequence": { "sequence": "MSCPESQKTGKNADSSPKQVIFKKSTRDKALTIYLGKRDFIDNIGSVEPVDGVVLVDPAMIKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLFFSRVQVYPPENRPESLSHLQESLLKKLGKNAYPFYFTFPDYLPCSVCLQPSPRDVDKSCGVDFEVKAFSTENLEERIHKRNSARLLIRKVQFAPEEPGPQPCAETTWQFFMSNKPLHLKACLSKEVYYHGEPIPVTVMVTNSTEKTVKKIKVQVEQVANVVLYSSDFYTKVVAAEEAPEKVQPNSSLTTTLTVLPLLANNRQTREIALDGKLKDEDTNLASSTIIKDGIDKTVMGILVSYKVRVKLTVSGLLGDFTSSEVSTELPFRLMHPKPEEKNPAGRSVIL", "length": 378, "header": "tr|A0A8V0ZU02-1|A0A8V0ZKQ9_CHICK Computationally mapped isoform of S-arrestin OS=Gallus gallus OX=9031 GN=SAG PE=3 SV=1 CANONICAL=A0A8V0ZKQ9-1" }, "locus": { "chromosome": "9", "start_pos": 838868, "end_pos": 827770, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056132.1", "url": "https://www.ensembl.org/id/ENSGALT00010056132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033957.1", "url": "https://www.ensembl.org/id/ENSGALP00010033957.1" } ] } }, { "isoform_ac": "A0A8V0ZU08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9/entry#A0A8V0ZU08-1", "sequence": { "sequence": "MSCPESQKTGKNADSSPKQVIFKKSTRDKALTIYLGKRDFIDNIGSVEPVDGVVLVDPAMIKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLFFSRVQVYPPENRPESLSHLQESLLKKLGKNAYPFYFTFPDYLPCSVCLQPSPRDVDKSCGVDFEVKAFSTENLEERIHKRNSARLLIRKVQFAPEEPGPQPCAETTWQFFMSNKPLHLKACLSKEVYYHGEPIPVTVMVTNSTEKTVKKIKVQVEQVANVVLYSSDFYTKVVAAEEAPEKVQPNSSLTTTLTVLPLLANNRQTREIALDGKLKDEDTNLASSTIIKDGIDKTVMGILVSYKVRVKLTVSGLLGDFTSSEVSTELPFRLMHPKPEEKNPAGKDGDAEMVFEEFARQQLKDTGDEEENKNVSSTDE", "length": 407, "header": "tr|A0A8V0ZU08-1|A0A8V0ZKQ9_CHICK Computationally mapped isoform of S-arrestin OS=Gallus gallus OX=9031 GN=SAG PE=3 SV=1 CANONICAL=A0A8V0ZKQ9-1" }, "locus": { "chromosome": "9", "start_pos": 842235, "end_pos": 827770, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056139.1", "url": "https://www.ensembl.org/id/ENSGALT00010056139.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033962.1", "url": "https://www.ensembl.org/id/ENSGALP00010033962.1" } ] } }, { "isoform_ac": "A0A8V0ZU14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9/entry#A0A8V0ZU14-1", "sequence": { "sequence": "MSCPESQKTGKNADSSPKQVIFKKSTRDKALTIYLGKRDFIDNIGSVEPVDGVVLVDPAMIKGKKVYVTLTCAFRYGQEDIDVIGLTFRRDLFFSRVQVYPPENRPESLSHLQESLLKKLGKNAYPFYFTFPDYLPCSVCLQPSPRDVDKSCGVDFEVKAFSTENLEERIHKRNSARLLIRKVQFAPEEPGPQPCAETTWQFFMSNKPLHLKACLSKEVYYHGEPIPVTVMVTNSTEKTVKKIKVQVEQVANVVLYSSDFYTKVVAAEEAPEKVQPNSSLTTTLTVLPLLANNRQTREIALDGKLKDEDTNLASSTIIKDGIDKTVMGILVSYKVRVKLTVSGLLGDFTSSEVSTELPFRLMHPKPEEKNPAVLQKRVQ", "length": 379, "header": "tr|A0A8V0ZU14-1|A0A8V0ZKQ9_CHICK Computationally mapped isoform of S-arrestin OS=Gallus gallus OX=9031 GN=SAG PE=3 SV=1 CANONICAL=A0A8V0ZKQ9-1" }, "locus": { "chromosome": "9", "start_pos": 842922, "end_pos": 827770, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056144.1", "url": "https://www.ensembl.org/id/ENSGALT00010056144.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033967.1", "url": "https://www.ensembl.org/id/ENSGALP00010033967.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2514859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2514859", "resource": "Reactome", "description": "Inactivation, recovery and regulation of the phototransduction cascade" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9" } ], "pmid": "" }, { "name": "sensory perception", "id": "GO:0007600", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007600", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9" } ], "pmid": "" }, { "name": "G protein-coupled receptor internalization", "id": "GO:0002031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor binding", "id": "GO:0001664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001664", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9" } ], "pmid": "" }, { "name": "phosphoprotein binding", "id": "GO:0051219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051219", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9" } ], "pmid": "" }, { "name": "opsin binding", "id": "GO:0002046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9" } ], "pmid": "" }, { "name": "photoreceptor outer segment", "id": "GO:0001750", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKQ9" }, { "id": "SM01017", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01017" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arrestin C-terminal-like", "eco_id": "ECO_0000259", "start_pos": 205, "end_pos": 366, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 277, "end_pos": 279 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMS4-1", "uniprot_ac": "A0A8V0ZMS4", "uniprot_id": "A0A8V0ZMS4_CHICK", "mass": { "chemical_mass": 55236.0, "monoisotopic_mass": 55236.0 }, "refseq": {}, "gene_names": [ { "name": "CCZ1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4" } ] } ], "protein_names": [ { "name": "CCZ1 vacuolar protein trafficking and biosis associated homolog (S. cerevisiae)", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4", "locus": { "chromosome": "14", "start_pos": 1015050, "end_pos": 1030079, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021827", "url": "https://www.ensembl.org/id/ENSGALG00010021827" } ] } } ], "crossref": [ { "id": "A0A8V0ZMS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR013176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKR2", "url": "https://www.orthodb.org/?gene=A0A8V0ZKR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMS4", "url": "https://www.orthodb.org/?gene=A0A8V0ZMS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMT2", "url": "https://www.orthodb.org/?gene=A0A8V0ZMT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13056:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13056:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19032", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19032", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZKR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAAAGAGQEKQLAPTLLSFFIYNPKLGPKEGEEEKKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPTKPAKSLHTQKNRQFFHEPEENFWMVMVVRNPIIEKHKDGKPVYEYQEEELLVDKVYSSVLQQCYSMYKLFNGTFLKAMEDGGVKVLKERLEKFFHRYLQTLHLQSCDLLDVFCGISFFPLDKMTYLKIQSFINRMEESLNIVKYTAFLYNDQLIWSGLEQDDMRILYKYLTTSLFPRHMEPELAGRDSPIRAEMPGNLQHYGRFLTGPLNLNDPEAKCRFPKIFVNTDDTYEELHLIVYKAMSAAVCFMIDASIPPTLEFCRKLDSIVGPQLTVLASDICEQYNINKRISGAEKEPQFKFIYFNHMNLAEKSTIHMRKTPSVSLASVHPDLMKILGDINSDFSRVDEDEEIIVKAMSDYWVVGKKSDQRELYVILNQKNANLIEVNEEVKKLCATQFNNIFFLD", "length": 476, "header": "tr|A0A8V0ZMS4-1|A0A8V0ZMS4_CHICK Isoform 1 of CCZ1 vacuolar protein trafficking and biosis associated homolog (S. cerevisiae) OS=Gallus gallus OX=9031 GN=CCZ1 PE=3 SV=1 CANONICAL=A0A8V0ZMS4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4/entry#A0A8V0ZKR2-1", "sequence": { "sequence": "MATAAAGAGQEKQLAPTLLSFFIYNPKLGPKEGEEEKKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPTKPAKSLHTQKNRQFFHEPEENFWMVMVVRNPIIEKHKDGKPVYEYQEEELLDKVYSSVLQQCYSMYKYLQTLHLQSCDLLDVFCGISFFPLDKMTYLKIQSFINRMEESLNIVKYTAFLYNDQLIWSGLEQDDMRILYKYLTTSLFPRHMEPELAGRDSPIRAEMPGNLQHYGRFLTGPLNLNDPEAKCRFPKIFVNTDDTYEELHLIVYKAMSAAVCFMIDASIPPTLEFCRKLDSIVGPQLTVLASDICEQYNINKRISGAEKEPQFKFIYFNHMNLAEKSTIHMRKTPSVSLASVHPDLMKILGDINSDFSRVDEDEEIIVKAMSDYWVVGKKSDQRELYVILNQKNANLIEVNEEVKKLCATQFNNIFFLD", "length": 447, "header": "tr|A0A8V0ZKR2-1|A0A8V0ZMS4_CHICK Computationally mapped isoform of CCZ1 vacuolar protein trafficking and biosis associated homolog (S. cerevisiae) OS=Gallus gallus OX=9031 GN=CCZ1 PE=3 SV=1 CANONICAL=A0A8V0ZMS4-1" }, "locus": { "chromosome": "14", "start_pos": 1029970, "end_pos": 1016526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053104.1", "url": "https://www.ensembl.org/id/ENSGALT00010053104.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031988.1", "url": "https://www.ensembl.org/id/ENSGALP00010031988.1" } ] } }, { "isoform_ac": "A0A8V0ZMS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4/entry#A0A8V0ZMS4-1", "sequence": { "sequence": "MATAAAGAGQEKQLAPTLLSFFIYNPKLGPKEGEEEKKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPTKPAKSLHTQKNRQFFHEPEENFWMVMVVRNPIIEKHKDGKPVYEYQEEELLVDKVYSSVLQQCYSMYKLFNGTFLKAMEDGGVKVLKERLEKFFHRYLQTLHLQSCDLLDVFCGISFFPLDKMTYLKIQSFINRMEESLNIVKYTAFLYNDQLIWSGLEQDDMRILYKYLTTSLFPRHMEPELAGRDSPIRAEMPGNLQHYGRFLTGPLNLNDPEAKCRFPKIFVNTDDTYEELHLIVYKAMSAAVCFMIDASIPPTLEFCRKLDSIVGPQLTVLASDICEQYNINKRISGAEKEPQFKFIYFNHMNLAEKSTIHMRKTPSVSLASVHPDLMKILGDINSDFSRVDEDEEIIVKAMSDYWVVGKKSDQRELYVILNQKNANLIEVNEEVKKLCATQFNNIFFLD", "length": 476, "header": "tr|A0A8V0ZMS4-1|A0A8V0ZMS4_CHICK Isoform 1 of CCZ1 vacuolar protein trafficking and biosis associated homolog (S. cerevisiae) OS=Gallus gallus OX=9031 GN=CCZ1 PE=3 SV=1 CANONICAL=A0A8V0ZMS4-1" }, "locus": { "chromosome": "14", "start_pos": 1029970, "end_pos": 1016526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053113.1", "url": "https://www.ensembl.org/id/ENSGALT00010053113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031994.1", "url": "https://www.ensembl.org/id/ENSGALP00010031994.1" } ] } }, { "isoform_ac": "A0A8V0ZMT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4/entry#A0A8V0ZMT2-1", "sequence": { "sequence": "MATAAAGAGQEKQLAPTLLSFFIYNPKLGPKEGEEEKKILFYHPNEVEKNEKIRNVGLCEAIVQFTRTFSPTKPAKSLHTQKNRQFFHEPEENFWMVMVVRNPIIEKHKDGKPVYEYQEEELLDKVYSSVLQQCYSMYKLFNGTFLKAMEDGGVKVLKERLEKFFHRYLQTLHLQSCDLLDVFCGISFFPLDKMTYLKIQSFINRMEESLNIVKYTAFLYNDQLICGLLWYDLRTLAGRDSPIRAEMPGNLQHYGRFLTGPLNLNDPEAKCRFPKIFVNTDDTYEELHLIVYKAMSAAVCFMIDASIPPTLEFCRKLDSIVGPQLTVLASDICEQYNINKRISGAEKEPQFKFIYFNHMNLAEKSTIHMRKTPSVSLASVHPDLMKILGDINSDFSRVDEDEEIIVKAMSDYWVVGKKSDQRELYVILNQKNANLIEVNEEVKKLCATQFNNIFFLD", "length": 457, "header": "tr|A0A8V0ZMT2-1|A0A8V0ZMT2_CHICK Computationally mapped isoform of CCZ1 vacuolar protein trafficking and biosis associated homolog (S. cerevisiae) OS=Gallus gallus OX=9031 GN=CCZ1 PE=3 SV=1 CANONICAL=A0A8V0ZMS4-1" }, "locus": { "chromosome": "14", "start_pos": 1029970, "end_pos": 1016526, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053119.1", "url": "https://www.ensembl.org/id/ENSGALT00010053119.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031999.1", "url": "https://www.ensembl.org/id/ENSGALP00010031999.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4" } ], "pmid": "" }, { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Mon1-Ccz1 complex", "id": "GO:0035658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035658", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4" }, { "id": "PF19032", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19032" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCZ1/INTU second Longin", "eco_id": "ECO_0000259", "start_pos": 214, "end_pos": 340, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4" }, { "id": "PF19033", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCZ1/INTU/HPS4 third Longin", "eco_id": "ECO_0000259", "start_pos": 366, "end_pos": 464, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMS4" }, { "id": "PF19031", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19031" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCZ1/INTU/HSP4 first Longin", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 144, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKS9-1", "uniprot_ac": "A0A8V0ZKS9", "uniprot_id": "A0A8V0ZKS9_CHICK", "mass": { "chemical_mass": 21496.0, "monoisotopic_mass": 21496.0 }, "refseq": {}, "gene_names": [ { "name": "C1orf50", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS9" } ] } ], "protein_names": [ { "name": "Chromosome 1 open reading frame 50", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1orf50", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS9", "locus": { "chromosome": "21", "start_pos": 6354436, "end_pos": 6360168, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021839", "url": "https://www.ensembl.org/id/ENSGALG00010021839" } ] } } ], "crossref": [ { "id": "A0A8V0ZKS9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKS9", "database": "AlphaFoldDB", "categories": [] }, { "id": "419506", "url": "https://www.ncbi.nlm.nih.gov/gene/419506", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KEWGANC", "url": "https://omabrowser.org/oma/group/KEWGANC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKS9", "url": "https://www.orthodb.org/?gene=A0A8V0ZKS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMU1", "url": "https://www.orthodb.org/?gene=A0A8V0ZMU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT77", "url": "https://www.orthodb.org/?gene=A0A8V0ZT77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14553", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14553", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14553:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14553:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZKS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GRAGTRCPAVPGSIPRQHRPVVPLCAGAFRRVVGSQKGSGWRNLADHPALSCLPPPPPQADEFVRANACNKLTVIAEQIRCLQEQARKVLEDANRDADLHHVACNLVKKPGNVYYLYRRESGQKYFSMLSPKEWGTSPHEFLGAYKLQHDLSWTPFEDIERRDAEMNVLDKLLSRQAALPPCTEPNFQGLTK", "length": 192, "header": "tr|A0A8V0ZKS9-1|A0A8V0ZKS9_CHICK Isoform 1 of Chromosome 1 open reading frame 50 OS=Gallus gallus OX=9031 GN=C1orf50 PE=4 SV=1 CANONICAL=A0A8V0ZKS9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS9/entry#A0A8V0ZKS9-1", "sequence": { "sequence": "GRAGTRCPAVPGSIPRQHRPVVPLCAGAFRRVVGSQKGSGWRNLADHPALSCLPPPPPQADEFVRANACNKLTVIAEQIRCLQEQARKVLEDANRDADLHHVACNLVKKPGNVYYLYRRESGQKYFSMLSPKEWGTSPHEFLGAYKLQHDLSWTPFEDIERRDAEMNVLDKLLSRQAALPPCTEPNFQGLTK", "length": 192, "header": "tr|A0A8V0ZKS9-1|A0A8V0ZKS9_CHICK Isoform 1 of Chromosome 1 open reading frame 50 OS=Gallus gallus OX=9031 GN=C1orf50 PE=4 SV=1 CANONICAL=A0A8V0ZKS9-1" }, "locus": { "chromosome": "21", "start_pos": 6359783, "end_pos": 6356752, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053131.1", "url": "https://www.ensembl.org/id/ENSGALT00010053131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032008.1", "url": "https://www.ensembl.org/id/ENSGALP00010032008.1" } ] } }, { "isoform_ac": "A0A8V0ZMU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS9/entry#A0A8V0ZMU1-1", "sequence": { "sequence": "MAAVGGEDGGGGGAGLALALVEGGAGRAARIGDPGDLVALAQQVQQADEFVRANACNKLTVIAEQIRCLQEQARKVLEDANRDADLHHVACNLVKKPGNVYYLYRRESGQKYFSMLSPKEWGTSPHEFLGAYKLQHDLSWTPFEDIERRDAEMNVLDKLLSRQAALPPCTEPNFQGLTK", "length": 179, "header": "tr|A0A8V0ZMU1-1|A0A8V0ZMU1_CHICK Computationally mapped isoform of Chromosome 1 open reading frame 50 OS=Gallus gallus OX=9031 GN=C1orf50 PE=1 SV=1 CANONICAL=A0A8V0ZKS9-1" }, "locus": { "chromosome": "21", "start_pos": 6359969, "end_pos": 6356752, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053132.1", "url": "https://www.ensembl.org/id/ENSGALT00010053132.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032009.1", "url": "https://www.ensembl.org/id/ENSGALP00010032009.1" } ] } }, { "isoform_ac": "A0A8V0ZT77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS9/entry#A0A8V0ZT77-1", "sequence": { "sequence": "MAEPAAARLRTRPRPLSVATPPTSDHAHKSPPAPVLAPPPEADEFVRANACNKLTVIAEQIRCLQEQARKVLEDANRDADLHHVACNLVKKPGNVYYLYRRESGQKYFSMLSPKEWGTSPHEFLGAYKLQHDLSWTPFEDIERRDAEMNVLDKLLSRQAALPPCTEPNFQGLTK", "length": 174, "header": "tr|A0A8V0ZT77-1|A0A8V0ZKS9_CHICK Computationally mapped isoform of Chromosome 1 open reading frame 50 OS=Gallus gallus OX=9031 GN=C1orf50 PE=4 SV=1 CANONICAL=A0A8V0ZKS9-1" }, "locus": { "chromosome": "21", "start_pos": 6360150, "end_pos": 6356752, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053135.1", "url": "https://www.ensembl.org/id/ENSGALT00010053135.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032012.1", "url": "https://www.ensembl.org/id/ENSGALP00010032012.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D4A7G9-1", "protein_name": "Similar to human chromosome 1 open reading frame 50", "gene_name": "C5h1orf50", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADPGVPDPFKRGTGNLGVQEAAGPGGALVELTPTPGGMALVSPYHTHRVGDPLDLVALAEQVQKADEFIRANATNKLTVIAEQIQHLQDQARKVLEDARRDADLHHVACNMVKKPGNIYYLYQRESGQKYFSIISPQVRTLAFNSESTPAFEKFWACLNENEWGAGCPHDFLGAYKLQHDMSWTPYEDVEKQDAKISMMDKLLSQPMALPPGTEPTFQGLTH", "length": 223 }, "evidence": [ { "id": "A0A8V0ZKS9", "url": "https://omabrowser.org/oma/group/A0A8V0ZKS9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5EBG8-1", "protein_name": "Uncharacterized protein C1orf50 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADPGVPGRYESGTGNLGVKEAAGPGGALVELTPTPGGLALVSPYHTHRVGDPLDLVALAEQVQKADEFIRANATNKLTVIAEQIQHLQEQARKVLEDARRDADLHHAACNMVKKPGNIYYLYQRESGQQYFSIISPEEWGTGCPHDFLGAYKLQHDMSWTPYEDVEKQDAKIGMMDKLLSQPMALPPCTEPTFQGLPH", "length": 199 }, "evidence": [ { "id": "A0A8V0ZKS9", "url": "https://omabrowser.org/oma/group/A0A8V0ZKS9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BV19-1", "protein_name": "Uncharacterized protein C1orf50", "gene_name": "C1orf50", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDAAAPGRTEGVLERQGAPPAAGQGGALVELTPTPGGLALVSPYHTHRAGDPLDLVALAEQVQKADEFIRANATNKLTVIAEQIQHLQEQARKVLEDAHRDANLHHVACNIVKKPGNIYYLYKRESGQQYFSIISPKEWGTSCPHDFLGAYKLQHDLSWTPYEDIEKQDAKISMMDTLLSQSVALPPCTEPNFQGLTH", "length": 199 }, "evidence": [ { "id": "A0A8V0ZKS9", "url": "https://omabrowser.org/oma/group/A0A8V0ZKS9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKV5-1", "uniprot_ac": "A0A8V0ZKV5", "uniprot_id": "A0A8V0ZKV5_CHICK", "mass": { "chemical_mass": 216766.0, "monoisotopic_mass": 216766.0 }, "refseq": {}, "gene_names": [ { "name": "KNDC1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5" } ] } ], "protein_names": [ { "name": "Kinase non-catalytic C-lobe domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2. May be involved in cellular senescence.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU1#function" }, { "database": "UniProtKB", "id": "ARBA00059522", "url": "https://www.uniprot.org/uniprotkb/ARBA00059522#function" }, { "database": "UniProtKB", "id": "A0A8V0ZMX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KNDC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5", "locus": {} } ], "crossref": [ { "id": "cd06224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423824", "url": "https://www.ncbi.nlm.nih.gov/gene/423824", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423824", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423824", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ASTCKVH", "url": "https://omabrowser.org/oma/group/ASTCKVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKT4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKU1", "url": "https://www.orthodb.org/?gene=A0A8V0ZKU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKV5", "url": "https://www.orthodb.org/?gene=A0A8V0ZKV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMJ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZMJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMX0", "url": "https://www.orthodb.org/?gene=A0A8V0ZMX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21560", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21560", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21560:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21560:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00618", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00618", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZKT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMX0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAAEDGFYEEAEVNCYDFEPLPTLLEDEENVSLADILSLRDSCLTEQDIWAICLECCHSLKSIAHSAIFQTLCITPDTLAFNTNGNVCFMEQLSDDPEGAFVPPEFDITGNTFEAHIYSLGATLKAAIEYIVEPETESEFGQDLHTLLEQMQEENPENRPDIESILSLCEEKLKIASSSSICRSLSAVGRRVLSIESFGASQDACDNMWKGRVFQKSLGSKLCSNEIYNIGDSPAAEDVAATCHKDSSVVPVVTGRESSLKEMQIDLDNEKTQHYLLATEEKKSKEDKHVVYTDGFASVALDIKSCVNDLERDGAFKKGSLRKIKTFPKLPLEPTETNHFFTSVTNSGPLARKNHFLMHDSLPLDNNNEVVFSKGNLNSLAISSPSKTEPKHHQVTDLHLEASCVRTQVSGMNLEEHMSLINGKKIGFISSDRKEDCSDTTSEVSNTAGMLKSPNQSITGAKKLDNYMASEDCTETFQGSNENSLSHFNKMTSVLTTKPSGSRYGSNLIRSPELSSGALSANNNEDNLCGGRGSEIRSNEQWISLKLLLSWYGKPLKDHELWALCHECLRTLHTCTDYPVILCLDTVLLDCHGRVLFTAPKAEESCDIIYLAPEIEEEDVDTEKVCIYSVAAVLWMAAKYSISPNHKLALPRKLKNLLLDMAKKNPEERPSVADAIKTCSHYLLEQGVNSKNILALLNKSVFKAVEEDVSSSPDNVAFEIEKERFEMNSSESSLGFMPITSESKLIAVKGPVPCQISLNCGKTALPVAFTSPATHFKPIILQQNANMTKEVHTPPTEKFKEKSRKEKRINRNKSGYVEGSKDCGIKDTDVVETTSEIPECHLQVPSHPFQTSLEKEKSGDVFTSDSSHILQERKILSEVPSSSLTSLISPNSLHINNIILKQNSEKRVLTFVPVHLAVSEQIPNKPLHSRVASDCSHSLPALLSSTIASYKLSMQTENDSSLLTVQNCKTINTQNAFEKTDQVVQSNCQDIEGATNMDSIFSEQGLTPYTSMDGEASCVFDGEVLSQQSRTNDALLQEVVHLIQEEFAFDGYLENGVEVFDMGNFILALKEIKFGTFSDKICEKFCDLYWDEKLLENLYQVVNGERASPLRITEADDSKCGSVFQDLKKSDSFLASSDHTEGEGEATFDMKDELMINTSLTEMTFYETPSDNFKKESWLQNTIPIEKDGRCLQSNGYHTGPDFAEENTEPEEEAIIKTAESSYLVPPNPPDFHGCSPGWSSAFYGAECFDSEVHSYMKNLGKQKSNESQSIDAIKVELEQLLMMETKNYRKTIKFYQKLLQKEKRNKGLETKSMLPKLRGQLQEMKSRVQFLELVKKYVQIMYAEQWGVESSILPTIIHNGRTDTMDVAPTDESSVLVYYNTEKHKCNNQNGIRVLQAGTPLGLMAYLYSRNAFLEGYVQQFLYTFRYFCTQEEFLQFILDRISSTLSSASLDPSSSLTKICNRSFYILQAWIEDCYHVDFATNASLLCTLKEFISSKVAPLNGYGEHLLSLLEDASAGKSGSSQQCSSMEKGEEEEEEDRKTLHSICKKLSEDMFRKNFNWKLSKGMGPIAHYQREQLYTISSVLPKPCYSSFTEEFPVSFAKADEVGPYLLTEYSVQQLCCQLTLLQQELFHKCHPVHFLNSRALGVKDKCVAVQKAVSTEEVSFKVCNLFLSKCIQDQYLIQLLRNADSVSTWVAAEIVTCHTSKLQVSLLSKFLLIAKSCYEQRNFATAMQILAGLENLIVRQLPVSLGLSVVTILPKIILFKYGIDDQQKCVFFYYKAWKILPAKVAEIMEELKAVEVFLKSDSLCLMEGERFKTLPTIPSAHVLAMHVQQLETGGFTMTNGAHKWTKLRNIAKVVSQVHAFQENPYTFTPDYKLQSYLRQRITRFKDADISALAADNCANFHHIPAEKHSRKIQDTLRRMKATFQ", "length": 1933, "header": "tr|A0A8V0ZKV5-1|A0A8V0ZKV5_CHICK Isoform 1 of Kinase non-catalytic C-lobe domain containing 1 OS=Gallus gallus OX=9031 GN=KNDC1 PE=4 SV=1 CANONICAL=A0A8V0ZKV5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5/entry#A0A8V0ZKT4-1", "sequence": { "sequence": "MEAAAEDGFYEEAEVNCYDFEPLPTLLEDEENVSLADILSLRDSCLTEQDIWAICLECCHSLKSIAHSAIFQTLCITPDTLAFNTNGNVCFMEQLSDDPEGAFVPPEFDITGNTFEAHIYSLGATLKAAIEYIVEPETESEFGQDLHTLLEQMQEENPENRPDIESILSLCEEKLKIASSSSICRSLSAVGRRVLSIESFGASQDACDNMWKGRVFQKSLGSKLCSNEIYNIGDSPAAEDVAATCHKDSSVVPVVTGRESSLKEMQIDLDNEKTQHYLLATEEKKSKEDKHVVYTDGFASVALDIKSCVNDLERDGAFKKGSLRKIKTFPKLPLEPTETNHFFTSVTNSGPLARKNHFLMHDSLPLDNNNEVVFSKGNLNSLAISSPSKTEPKHHQVTDLHLEASCVRTQVSGMNLEEHMSLINGKKIGFISSDRKEDCSDTTSEVSNTAGMLKSPNQSITGAKKLDNYMASEDCTETFQGSNENSLSHFNKMTSVLTTKPSGSRYGSNLIRSPELSSGALSANNNEDNLCGGRGSEIRSNEQRVCNTGSIWLKINLVYSGEQTVFFPYLSLILLQWTIFF", "length": 581, "header": "tr|A0A8V0ZKT4-1|A0A8V0ZKV5_CHICK Computationally mapped isoform of Kinase non-catalytic C-lobe domain containing 1 OS=Gallus gallus OX=9031 GN=KNDC1 PE=4 SV=1 CANONICAL=A0A8V0ZKV5-1" }, "locus": { "chromosome": "6", "start_pos": 22380819, "end_pos": 22352242, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053137.1", "url": "https://www.ensembl.org/id/ENSGALT00010053137.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032013.1", "url": "https://www.ensembl.org/id/ENSGALP00010032013.1" } ] } }, { "isoform_ac": "A0A8V0ZKU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5/entry#A0A8V0ZKU1-1", "sequence": { "sequence": "MEAAAEDGFYEEAEVNCYDFEPLPTLLEDEENVSLADILSLRDSCLTEQDIWAICLECCHSLKSIAHSAIFQTLCITPDTLAFNTNGNVCFMEQLSDDPEGAFVPPEFDITGNTFEAHIYSLGATLKAAIEYIVEPETESEFGQDLHTLLEQMQEENPENRPDIESILSLCEEKLKIASSSSICRSLSAVGRRVLSIESFGASQDACDNMWKGRVFQKSLGSKLCSNEIYNIGDSPAAEDVAATCHKDSSVVPVVTGRESSLKEMQIDLDNEKTQHYLLATEEKKSKEDKHVVYTDGFASVALDIKSCVNDLERDGAFKKGSLRKIKTFPKLPLEPTETNHFFTSVTNSGPLARKNHFLMHDSLPLDNNNEVVFSKGNLNSLAISSPSKTEPKHHQVTDLHLEASCVRTQVSGMNLEEHMSLINGKKIGFISSDRKEDCSDTTSEVSNTAGMLKSPNQSITGAKKLDNYMASEDCTETFQGSNENSLSHFNKMTSVLTTKPSGSRYGSNLIRSPELSSGALSANNNEDNLCGGRGSEIRSNEQWISLKLLLSWYGKPLKDHELWALCHECLRTLHTCTDYPVILCLDTVLLDCHGRVLFTAPKAEESCDIIYLAPEIEEEDVDTEKVCIYSVAAVLWMAAKYSISPNHKLALPRKLKNLLLDMAKKNPEERPSVADAIKTCSHYLLEQGVNSKNILALLNKSVFKAVEEDVSSSPDNVAFEIEKERFEMNSSESSLGFMPITSESKLIAVKGPVPCQISLNCGKTALPVAFTSPATHFKPIILQQNANMTKEVHTPPTEKFKEKSRKEKRINRNKSGYVEGSKDCGIKDTDVVETTSEIPECHLQVPSHPFQTSLEKEKSGDVFTSDSSHILQERKILSEVPSSSLTSLISPNSLHINNIILKQNSEKRVLTFVPVHLAVSEQIPNKPLHSRVASDCSHSLPALLSSTIASYKLSMQTENDSSLLTVQNCKTINTQNAFEKTDQVVQSNCQDIEGATNMDSIFSEQGLTPYTSMDGEASCVFDGEVLSQQSRTNDALLQEVVHLIQEEFAFDGYLENGVEVFDMGNFILALKEIKFGTFSDKICEKFCDLYWDEKLLENLYQVVNGERASPLRITEADDSKCGSVFQDLKKSDSFLASSDHTEGEGEATFDMKDELMINTSLTEMTFYETPSDNFKKESWLQNTIPIEKDGRCLQSNGYHTGPDFAEENTEPEEEAIIKTAESSYLVPPNPPDFHGCSPGWSSAFYGAECFDSEVHSYMKNLGKQKSNESQSIDAIKVELEQLLMMETKNYRKTIKFYQKLLQKEKRNKGLETKSMLPKLRGQLQEMKSRVQFLELVKKYVQIMYAEQWGVESSILPTIIHNGRTDTMDVAPTDESSVLVYYNTEKHKCNNQNGIRVLQAGTPLGLMAYLYSRNAFLEGYVQQFLYTFRYFCTQEEFLQFILDRISSTLSSASLDPSSSLTKICNRSFYILQAWIEDCYHVDFATNASLLCTLKEFISSKVAPLNGYGEHLLSLLEDASAGKSGSSQQCSSMEKGEEEEEEDRKTLHSICKKLSEDMFRKELFHKCHPVHFLNSRALGVKDKCVAVQKAVSTEEVSFKVCNLFLSKCIQDQYLIQLLRNADSVSTWVAAEIVTCHTSKLQVSLLSKFLLIAKSCYEQRNFATAMQILAGLENLIVRQLPAWKILPAKVAEIMEELKAVEVFLKSDSLCLMEGERFKTLPTIPSAHVLAMHVQQLETGGFTMTNGAHKWTKLRNIAKVVSQVHAFQENPYTFTPDYKLQSYLRQRITRFKDADISALAADNCANFHHIPAEKHSRKIQDTLRRMKATFQ", "length": 1828, "header": "tr|A0A8V0ZKU1-1|A0A8V0ZKU1_CHICK Computationally mapped isoform of Kinase non-catalytic C-lobe domain-containing protein 1 OS=Gallus gallus OX=9031 GN=KNDC1 PE=4 SV=1 CANONICAL=A0A8V0ZKV5-1" }, "locus": { "chromosome": "6", "start_pos": 22380819, "end_pos": 22324484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053147.1", "url": "https://www.ensembl.org/id/ENSGALT00010053147.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032018.1", "url": "https://www.ensembl.org/id/ENSGALP00010032018.1" } ] } }, { "isoform_ac": "A0A8V0ZKV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5/entry#A0A8V0ZKV5-1", "sequence": { "sequence": "MEAAAEDGFYEEAEVNCYDFEPLPTLLEDEENVSLADILSLRDSCLTEQDIWAICLECCHSLKSIAHSAIFQTLCITPDTLAFNTNGNVCFMEQLSDDPEGAFVPPEFDITGNTFEAHIYSLGATLKAAIEYIVEPETESEFGQDLHTLLEQMQEENPENRPDIESILSLCEEKLKIASSSSICRSLSAVGRRVLSIESFGASQDACDNMWKGRVFQKSLGSKLCSNEIYNIGDSPAAEDVAATCHKDSSVVPVVTGRESSLKEMQIDLDNEKTQHYLLATEEKKSKEDKHVVYTDGFASVALDIKSCVNDLERDGAFKKGSLRKIKTFPKLPLEPTETNHFFTSVTNSGPLARKNHFLMHDSLPLDNNNEVVFSKGNLNSLAISSPSKTEPKHHQVTDLHLEASCVRTQVSGMNLEEHMSLINGKKIGFISSDRKEDCSDTTSEVSNTAGMLKSPNQSITGAKKLDNYMASEDCTETFQGSNENSLSHFNKMTSVLTTKPSGSRYGSNLIRSPELSSGALSANNNEDNLCGGRGSEIRSNEQWISLKLLLSWYGKPLKDHELWALCHECLRTLHTCTDYPVILCLDTVLLDCHGRVLFTAPKAEESCDIIYLAPEIEEEDVDTEKVCIYSVAAVLWMAAKYSISPNHKLALPRKLKNLLLDMAKKNPEERPSVADAIKTCSHYLLEQGVNSKNILALLNKSVFKAVEEDVSSSPDNVAFEIEKERFEMNSSESSLGFMPITSESKLIAVKGPVPCQISLNCGKTALPVAFTSPATHFKPIILQQNANMTKEVHTPPTEKFKEKSRKEKRINRNKSGYVEGSKDCGIKDTDVVETTSEIPECHLQVPSHPFQTSLEKEKSGDVFTSDSSHILQERKILSEVPSSSLTSLISPNSLHINNIILKQNSEKRVLTFVPVHLAVSEQIPNKPLHSRVASDCSHSLPALLSSTIASYKLSMQTENDSSLLTVQNCKTINTQNAFEKTDQVVQSNCQDIEGATNMDSIFSEQGLTPYTSMDGEASCVFDGEVLSQQSRTNDALLQEVVHLIQEEFAFDGYLENGVEVFDMGNFILALKEIKFGTFSDKICEKFCDLYWDEKLLENLYQVVNGERASPLRITEADDSKCGSVFQDLKKSDSFLASSDHTEGEGEATFDMKDELMINTSLTEMTFYETPSDNFKKESWLQNTIPIEKDGRCLQSNGYHTGPDFAEENTEPEEEAIIKTAESSYLVPPNPPDFHGCSPGWSSAFYGAECFDSEVHSYMKNLGKQKSNESQSIDAIKVELEQLLMMETKNYRKTIKFYQKLLQKEKRNKGLETKSMLPKLRGQLQEMKSRVQFLELVKKYVQIMYAEQWGVESSILPTIIHNGRTDTMDVAPTDESSVLVYYNTEKHKCNNQNGIRVLQAGTPLGLMAYLYSRNAFLEGYVQQFLYTFRYFCTQEEFLQFILDRISSTLSSASLDPSSSLTKICNRSFYILQAWIEDCYHVDFATNASLLCTLKEFISSKVAPLNGYGEHLLSLLEDASAGKSGSSQQCSSMEKGEEEEEEDRKTLHSICKKLSEDMFRKNFNWKLSKGMGPIAHYQREQLYTISSVLPKPCYSSFTEEFPVSFAKADEVGPYLLTEYSVQQLCCQLTLLQQELFHKCHPVHFLNSRALGVKDKCVAVQKAVSTEEVSFKVCNLFLSKCIQDQYLIQLLRNADSVSTWVAAEIVTCHTSKLQVSLLSKFLLIAKSCYEQRNFATAMQILAGLENLIVRQLPVSLGLSVVTILPKIILFKYGIDDQQKCVFFYYKAWKILPAKVAEIMEELKAVEVFLKSDSLCLMEGERFKTLPTIPSAHVLAMHVQQLETGGFTMTNGAHKWTKLRNIAKVVSQVHAFQENPYTFTPDYKLQSYLRQRITRFKDADISALAADNCANFHHIPAEKHSRKIQDTLRRMKATFQ", "length": 1933, "header": "tr|A0A8V0ZKV5-1|A0A8V0ZKV5_CHICK Isoform 1 of Kinase non-catalytic C-lobe domain containing 1 OS=Gallus gallus OX=9031 GN=KNDC1 PE=4 SV=1 CANONICAL=A0A8V0ZKV5-1" }, "locus": { "chromosome": "6", "start_pos": 22380819, "end_pos": 22324484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053169.1", "url": "https://www.ensembl.org/id/ENSGALT00010053169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032034.1", "url": "https://www.ensembl.org/id/ENSGALP00010032034.1" } ] } }, { "isoform_ac": "A0A8V0ZMJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5/entry#A0A8V0ZMJ1-1", "sequence": { "sequence": "MEQLSDDPEGAFVPPEFDITGNTFEAHIYSLGATLKAAIEYIVEPETESEFGQDLHTLLEQMQEENPENRPDIESILSLCEEKLKIASSSSICRSLSAVGRRVLSIESFGASQDACDNMWKGRVFQKSLGSKLCSNEIYNIGDSPAAEDVAATCHKDSSVVPVVTGRESSLKEMQIDLDNEKTQHYLLATEEKKSKEDKHVVYTDGFASVALDIKSCVNDLERDGAFKKGSLRKIKTFPKLPLEPTETNHFFTSVTNSGPLARKNHFLMHDSLPLDNNNEVVFSKGNLNSLAISSPSKTEPKHHQVTDLHLEASCVRTQVSGMNLEEHMSLINGKKIGFISSDRKEDCSDTTSEVSNTAGMLKSPNQSITGAKKLDNYMASEDCTETFQGSNENSLSHFNKMTSVLTTKPSGSRYGSNLIRSPELSSGALSANNNEDNLCGGRGSEIRSNEQWISLKLLLSWYGKPLKDHELWALCHECLRTLHTCTDYPVILCLDTVLLDCHGRVLFTAPKAEESCDIIYLAPEIEEEDVDTEKVCIYSVAAVLWMAAKYSISPNHKLALPRKLKNLLLDMAKKNPEERPSVADAIKTCSHYLLEQGVNSKNILALLNKSVFKAVEEDVSSSPDNVAFEIEKERFEMNSSESSLGFMPITSESKLIAVKGPVPCQISLNCGKTALPVAFTSPATHFKPIILQQNANMTKEVHTPPTEKFKEKSRKEKRINRNKSGYVEGSKDCGIKDTDVVETTSEIPECHLQVPSHPFQTSLEKEKSGDVFTSDSSHILQERKILSEVPSSSLTSLISPNSLHINNIILKQNSEKRVLTFVPVHLAVSEQIPNKPLHSRVASDCSHSLPALLSSTIASYKLSMQTENDSSLLTVQNCKTINTQNAFEKTDQVVQSNCQDIEGATNMDSIFSEQGLTPYTSMDGEASCVFDGEVLSQQSRTNDALLQEVVHLIQEEFAFDGYLENGVEVFDMGNFILALKEIKFGTFSDKICEKFCDLYWDEKLLENLYQVVNGERASPLRITEADDSKCGSVFQDLKKSDSFLASSDHTEGEGEATFDMKDELMINTSLTEMTFYETPSDNFKKESWLQNTIPIEKDGRCLQSNGYHTGPDFAEENTEPEEEAIIKTAESSYLVPPNPPDFHGCSPGWSSAFYGAECFDSEVHSYMKNLGKQKSNESQSIDAIKVELEQLLMMETKNYRKTIKFYQKLLQKEKRNKGLETKSMLPKLRGQLQEMKSRVQFLELVKKYVQIMYAEQWGVESSILPTIIHNGRTDTMDVAPTDESSVLVYYNTEKHKCNNQNGIRVLQAGTPLGLMAYLYSRNAFLEGYVQQFLYTFRYFCTQEEFLQFILDRISSTLSSASLDPSSSLTKICNRSFYILQAWIEDCYHVDFATNASLLCTLKEFISSKVAPLNGYGEHLLSLLEDASAGKSGSSQQCSSMEKGEEEEEEDRKTLHSICKKLSEDMFRKNFNWKLSKGMGPIAHYQREQLYTISSVLPKPCYSSFTEEFPVSFAKADEVGPYLLTEYSVQQLCCQLTLLQQELFHKCHPVHFLNSRALGVKDKCVAVQKAVSTEEVSFKVCNLFLSKCIQDQYLIQLLRNADSVSTWVAAEIVTCHTSKLQVSLLSKFLLIAKSCYEQRNFATAMQILAGLENLIVRQLPAWKILPAKVAEIMEELKAVEVFLKSDSLCLMEGERFKTLPTIPSAHVLAMHVQQLETGGFTMTNGAHKWTKLRNIAKVVSQVHAFQENPYTFTPDYKLQSYLRQRITRFKDADISALAADNCANFHHIPAEKHSRKIQDTLRRMKATFQ", "length": 1809, "header": "tr|A0A8V0ZMJ1-1|A0A8V0ZMJ1_CHICK Computationally mapped isoform of Kinase non-catalytic C-lobe domain containing 1 OS=Gallus gallus OX=9031 GN=KNDC1 PE=4 SV=1 CANONICAL=A0A8V0ZKV5-1" }, "locus": { "chromosome": "6", "start_pos": 22376296, "end_pos": 22324484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053158.1", "url": "https://www.ensembl.org/id/ENSGALT00010053158.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032026.1", "url": "https://www.ensembl.org/id/ENSGALP00010032026.1" } ] } }, { "isoform_ac": "A0A8V0ZMX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5/entry#A0A8V0ZMX0-1", "sequence": { "sequence": "MEAAAEDGFYEEAEVNCYDFEPLPTLLEDEENVSLADILSLRDSCLTEQDIWAICLECCHSLKSIAHSAIFQTLCITPDTLAFNTNGNVCFMEQLSDDPEGAFVPPEFDITGNTFEAHIYSLGATLKAAIEYIVEPETESEFGQDLHTLLEQMQEENPENRPDIESILSLCEEKLKIASSSSICRSLSAVGRRVLSIESFGASQDACDNMWKGRVFQKSLGSKLCSNEIYNIGDSPAAEDVAATCHKDSSVVPVVTGRESSLKEMQIDLDNEKTQHYLLATEEKKSKEDKHVVYTDGFASVALDIKSCVNDLERDGAFKKGSLRKIKTFPKLPLEPTETNHFFTSVTNSGPLARKNHFLMHDSLPLDNNNEVVFSKGNLNSLAISSPSKTEPKHHQVTDLHLEASCVRTQVSGMNLEEHMSLINGKKIGFISSDRKEDCSDTTSEVSNTAGMLKSPNQSITGAKKLDNYMASEDCTETFQGSNENSLSHFNKMTSVLTTKPSGSRYGSNLIRSPELSSGALSANNNEDNLCGGRGSEIRSNEQWISLKLLLSWYGKPLKDHELWALCHECLRTLHTCTDYPVILCLDTVLLDCHGRVLFTAPKAEESCDIIYLAPEIEEEDVDTEKVCIYSVAAVLWMAAKYSISPNHKLALPRKLKNLLLDMAKKNPEERPSVADAIKTCSHYLLEQGVNSKNILALLNKSVFKAVEEDVSSSPDNVAFEIEKERFEMNSSESSLGFMPITSESKLIAVKGPVPCQISLNCGKTALPVAFTSPATHFKPIILQQNANMTKEVHTPPTEKFKEKSRKEKRINRNKSGYVEGSKDCGIKDTDVVETTSEIPECHLQVPSHPFQTSLEKEKSGDVFTSDSSHILQERKILSEVPSSSLTSLISPNSLHINNIILKQNSEKRVLTFVPVHLAVSEQIPNKPLHSRVASDCSHSLPALLSSTIASYKLSMQTENDSSLLTVQNCKTINTQNAFEKTDQVVQSNCQDIEGATNMDSIFSEQGLTPYTSMDGEASCVFDGEVLSQQSRTNDALLQEVVHLIQEEFAFDGYLENGVEVFDMGNFILALKEIKFGTFSDKICEKFCDLYWDEKLLENLYQVVNGERASPLRITEADDSKCGSVFQDLKKSDSFLASSDHTEGEGEATFDMKDELMINTSLTEMTFYETPSDNFKKESWLQNTIPIEKDGRCLQSNGYHTGPDFAEENTEPEEEAIIKTAESSYLVPPNPPDFHGCSPGWSSAFYGAECFDSEVHSYMKNLGKQKSNESQSIDAIKVELEQLLMMETKNYRKTIKFYQKLLQKEKRNKGLETKSMLPKLRGQLQEMKSRVQFLELVKKYVQIMYAEQWGVESSILPTIIHNGRTDTMDVAPTDESSVLVYYNTEKHKCNNQNGIRVLQAGTPLGLMAYLYSRNAFLEGYVQQFLYTFRYFCTQEEFLQFILDRISSTLSSASLDPSSSLTKICNRSFYILQAWIEDCYHVDFATNASLLCTLKEFISSKVAPLNGYGEHLLSLLEDASAGKSGSSQQCSSMEKGEEEEEEDRKTLHSICKKLSEDMFRKNFNWKLSKGMGPIAHYQREQLYTISSVLPKPCYSSFTEEFPVSFAKADEVGPYLLTEYSVQQLCCQLTLLQQELFHKCHPVHFLNSRALGVKDKCVAVQKAVSTEEVSFKVCNLFLSKCIQDQYLIQLLRNADSVSTWVAAEIVTCHTSKLQVSLLSKFLLIAKSCYEQRNFATAMQILAGLENLIVRQLPAWKILPAKVAEIMEELKAVEVFLKSDSLCLMEGERFKTLPTIPSAHVLAMHVQQLETGGFTMTNGAHKWTKLRNIAKVVSQVHAFQENPYTFTPDYKLQSYLRQRITRFKDADISALAADNCANFHHIPAEKHSRKIQDTLRRMKATFQ", "length": 1900, "header": "tr|A0A8V0ZMX0-1|A0A8V0ZMX0_CHICK Computationally mapped isoform of Kinase non-catalytic C-lobe domain-containing protein 1 OS=Gallus gallus OX=9031 GN=KNDC1 PE=4 SV=1 CANONICAL=A0A8V0ZKV5-1" }, "locus": { "chromosome": "6", "start_pos": 22380819, "end_pos": 22324484, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053176.1", "url": "https://www.ensembl.org/id/ENSGALT00010053176.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032040.1", "url": "https://www.ensembl.org/id/ENSGALP00010032040.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1373, "start_aa": "Thr", "end_pos": 1373, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1373", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423824", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423824", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A8Q2-1", "protein_name": "Kinase non-catalytic C-lobe domain-containing protein 1", "gene_name": "Kndc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQAMDPASRGFYEEDGKDLDFYDFEPLPTLPEDEENVSLADILSLRDRGLSEQEAWAVCLECSLSMRSVAHAAIFQTLCITPDTLAFNTSGNVCFMEQLSDDPEGAFVPPEFDLTGNTFEAHIYSLGATLKAALEYVTEPELEPKLSTDLEGLLRQMQAEDPRDRPDLQSIIALCEEKMQPVSSCRLCRSLSAIGRRVLSIESFGAFQELSENTWRGRPAPRNVGPKKMPGDLSTDPEALSSSKGLLQPPASRDAEQEAGQRPRAPSPKPLLSAPMRNGENPGQEGLANLVLDARCPLGELDRDILRRSRLKKAQTFPRLLQESTEASTLCLSLNSSRNQLAKSEFFPPDPRKLFLEGKNGLSGFKTQSKSRLWPEQEPGVPLDMTPGAGRNPHRSPGASGQLEATSPSQGSVEYKPSPSPVDPGDSDHEDQIPRSEEKIPEESRQLGSAATEQSLSLQDLLSKLGRPFREYELWALCLSCLSTLQTHKEHPARLCLDNVLVAEDGTVFFGPPPDDGAYNSLFLAPEVSEEKLVTEKASVYCVAAVLWTAAKFSVPRDHKLALPRRLKTLLLDMARRHASERPSAAEAIKVCSSYLLQRGMDSSKILAHLRASTCKVHPEEETIGLQNAFSVVDLKPTMAPAPESSPGFLQVSNDTKLVAVPEPVSGLPPCCIEACELPAAFTSEATHFKPIVLAQDMGVTRDQLALSSGSNEKPKEGSGQLDREGTRKQATLELLEDTDLKMSDQLPHGPELQGATPDPAGDSVPHSSATECSCPHGPALVTQQKGASGTPSSPASSLPSEHRPDGQGPLGTTVPPGPASASQGSRHPCKPPRGKAAASPSSPRGPDGHPEKARPADRKLCPSGVDTSSPPKMTACPSLQEAMRLIQEEFAFDGYMDNGLEALIMGEYIYALKDLTFATFCGAISEKFCDLYWDEQLLKNLFKVVNGPASPSESTSEEPGSQPERSPSRCSLSSKRPSLHGLGKEKPATTWGSGGPCSPTALSDIDSDTISQGNFEVGFRSQRSIKVTREQQPEAEVDGQPGPSQESTGNASDTVARLARSEDGGPAVSPGAADFQNCSPGWSSAFYEADCFGADVYNYVKDLERQKANGHTELEAQSPELEQQLMIEKRNYRKTLKFYQKLLQKEKRSKGSEVRTMLSKLRGQLDEMKSKVQFLGLVKKYLQVLYAERWGLEPCALPVIVNIAASPCDTLDFSPLDESSSLIFYNVNKHPCSGRQKKARILQAGTPLGLMAYLYSSDAFLEGYVQQFLYTFRYFCTPHDFLHFLLDRISSTLSRAHQDPTSTFTKIYRRSLCVLQAWVEDCYTVDFIRNAGLLGQLEDFISSKILPLDGTAEHLLGLLEVGTERRADSASRGADLEDPKEAEEDTRPFNALCKRFSEDGITRKSFSWRLPRGNGLVLPHHKERQYTIASALPKPCFFEDFYGPYAKASEKGPYFLTEYSTNQLFTQLTLLQQELFQKCHPVHFLNSRALGVMDKSAAIPKVSSSESLSAKTCSLFLPNYVQDKYLLQLLRNADDVSTWVAAEIVTSHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILGGLEHLAVRQSPAWRILPAKIAEVMEELKAVEVFLKSDSLCLMEGRRFRAQPTLPSAHLLAMHIQQLETGGFTMTNGAHRWSKLRNIAKVASQVHAFQENPYTFSPDPKLQAHLKQRIARFSGADVAILAADNRANFHQIPGEKHSRKIQDKLRRMKATFQ", "length": 1742 }, "evidence": [ { "id": "A0A8V0ZKV5", "url": "https://omabrowser.org/oma/group/A0A8V0ZKV5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0KK55-1", "protein_name": "Kinase non-catalytic C-lobe domain-containing protein 1", "gene_name": "Kndc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1742 }, "evidence": [ { "id": "A0A8V0ZKV5", "url": "https://omabrowser.org/oma/group/A0A8V0ZKV5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q76NI1-1", "protein_name": "Kinase non-catalytic C-lobe domain-containing protein 1", "gene_name": "KNDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1749 }, "evidence": [ { "id": "A0A8V0ZKV5", "url": "https://omabrowser.org/oma/group/A0A8V0ZKV5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5" } ], "pmid": "" }, { "name": "regulation of dendrite morphogenesis", "id": "GO:0048814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor complex", "id": "GO:0032045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1159, "end_pos": 1161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1268, "end_pos": 1270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1465, "end_pos": 1467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1486, "end_pos": 1488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 788, "end_pos": 790, "annotation": "n_glycosylation_sequon" }, { "start_pos": 814, "end_pos": 816, "annotation": 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"A0A8V0ZKU7_CHICK", "mass": { "chemical_mass": 11518.0, "monoisotopic_mass": 11518.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Secreted protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKU7", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZKU7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKU7", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0ZKU7", "url": 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"length": 1217, "header": "tr|A0A8V0ZKV3-1|A0A8V0ZKV3_CHICK Isoform 1 of Transmembrane protein 132A OS=Gallus gallus OX=9031 GN=TMEM132A PE=1 SV=1 CANONICAL=A0A8V0ZKV3-1" }, "locus": { "chromosome": "5", "start_pos": 240992, "end_pos": 235538, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049498.1", "url": "https://www.ensembl.org/id/ENSGALT00010049498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029250.1", "url": "https://www.ensembl.org/id/ENSGALP00010029250.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1177, "start_aa": "Thr", "end_pos": 1177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1177", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", 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"https://www.ensembl.org/id/ENSGALP00010034009.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" }, { "name": "I band", "id": "GO:0031674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" }, { "name": "RNA polymerase II, core complex", "id": "GO:0005665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005665", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" }, { "name": "DNA-directed RNA polymerase complex", "id": "GO:0000428", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000428", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transcription initiation at RNA polymerase II promoter", "id": "GO:0006367", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006367", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" }, { "name": "maintenance of ER location", "id": "GO:0051685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051685", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" }, { "name": "transcription elongation factor activity", "id": "GO:0003711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003711", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": 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This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004947545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947545" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM43B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ4", "locus": { "chromosome": "21", "start_pos": 4886376, "end_pos": 4889560, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021893", "url": "https://www.ensembl.org/id/ENSGALG00010021893" } ] } } ], "crossref": [ { "id": "A0A8V0ZKZ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858896", "url": "https://www.ncbi.nlm.nih.gov/gene/100858896", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858896", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858896", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TPCEKGA", "url": "https://omabrowser.org/oma/group/TPCEKGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKZ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004947545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLPWRRSKFVLVENERKCKGKSLGPGLGYASLLAGFLRSCPDLLPECPLERLGAVFGGRRQKVELNKEDPTYTVRYLGNAVTLHAKGEGCTEEAVGKIWAKSDAGAGGAKMKLTLGPHGIRMAPGEKGARRSGHAYLLHRITYCTADRRHPKVFAWVYRHQVKNKAVVLRCHAVLVPKAATARAMALLLFQTSASAFDEFKRLKRQNDGRRLQQQLLGEAIVPLVPLRRLLNAKCPYRPPAERARCAPRLSSILEEDEEETGGTWGDGGPTVVSLASEMRGCSLRGPRAPIC", "length": 292, "header": "tr|A0A8V0ZKZ4-1|A0A8V0ZKZ4_CHICK Isoform 1 of Family with sequence similarity 43 member B OS=Gallus gallus OX=9031 GN=FAM43B PE=4 SV=1 CANONICAL=A0A8V0ZKZ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ4/entry#A0A8V0ZKZ4-1", "sequence": { "sequence": "MLPWRRSKFVLVENERKCKGKSLGPGLGYASLLAGFLRSCPDLLPECPLERLGAVFGGRRQKVELNKEDPTYTVRYLGNAVTLHAKGEGCTEEAVGKIWAKSDAGAGGAKMKLTLGPHGIRMAPGEKGARRSGHAYLLHRITYCTADRRHPKVFAWVYRHQVKNKAVVLRCHAVLVPKAATARAMALLLFQTSASAFDEFKRLKRQNDGRRLQQQLLGEAIVPLVPLRRLLNAKCPYRPPAERARCAPRLSSILEEDEEETGGTWGDGGPTVVSLASEMRGCSLRGPRAPIC", "length": 292, "header": "tr|A0A8V0ZKZ4-1|A0A8V0ZKZ4_CHICK Isoform 1 of Family with sequence similarity 43 member B OS=Gallus gallus OX=9031 GN=FAM43B PE=4 SV=1 CANONICAL=A0A8V0ZKZ4-1" }, "locus": { "chromosome": "21", "start_pos": 4888713, "end_pos": 4887838, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053244.1", "url": "https://www.ensembl.org/id/ENSGALT00010053244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032090.1", "url": "https://www.ensembl.org/id/ENSGALP00010032090.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858896", "name": "", "url": 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"sequence": "MLPWRRNKFVLVEDDAKRKAKSLSPGLAYTSLLSSFLRSCPDLLPDWPLERLGRVFRSRRQKVELNKEDPTYTVWYLGNAVTLHAKGDGCTDDAVGKIWARCGPGGGTKMKLTLGPHGLRMQPCERSSSGGPGGRRPAHAYLLPRITYCAADARHPRVFTWVYRHQARHKAVVLRCHAVLLARAHKARALARLLRQTALAAFTDFKRLQRQSDARHVRQQHLRAGGAPAASLPRAPLRRLLNAKCAYRPPPAAERGRGAPRLSSIQEEDEDQDEDTLPENQEGGLGSWPPGETVGLPVARLAFLERPALGRHSYSGKNSGPGELRPGPRWHLSTANPHKEECPASVPGLATPWRTSGTSLLCLWRKRGCSYHPQLQTAQEQLFASGRCPSLCPGTHRTPHPPCLSAYKCVWVPARCPTARTKTWPPREVRGHLAGV", "length": 436 }, "evidence": [ { "id": "A0A8V0ZKZ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZKZ4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6ZT52-1", "protein_name": "Protein FAM43B", "gene_name": "FAM43B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPWRRNKFVLVEDEAKCKAKSLSPGLAYTSLLSSFLRSCPDLLPDWPLERLGRVFRSRRQKVELNKEDPTYTVWYLGNAVTLHAKGDGCTDDAVGKIWARCGPGGGTKMKLTLGPHGIRMQPCERSAAGGSGGRRPAHAYLLPRITYCTADGRHPRVFAWVYRHQARHKAVVLRCHAVLLARAHKARALARLLRQTALAAFSDFKRLQRQSDARHVRQQHLRAGGAAASVPRAPLRRLLNAKCAYRPPPSERSRGAPRLSSIQEEDEEEEEDDAEEQEGGVPQRERPEVLSLARELRTCSLRGAPAPPPPAQPRRWKAGPRERAGQAR", "length": 329 }, "evidence": [ { "id": "A0A8V0ZKZ4", "url": "https://omabrowser.org/oma/group/A0A8V0ZKZ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZKZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ4" }, { "id": "SM00462", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 206, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZKZ6-1", "uniprot_ac": "A0A8V0ZKZ6", "uniprot_id": "A0A8V0ZKZ6_CHICK", "mass": { "chemical_mass": 32526.0, "monoisotopic_mass": 32526.0 }, "refseq": { "ac": "XP_417366", "name": "mitochondrial import receptor subunit TOM34", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417366" }, "gene_names": [ { "name": "TOMM34", "type": "recommended", "evidence": [ { "id": "A0A8V0ZKZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ6" } ] }, { "name": "TOMM34", "type": "synonym", "evidence": [ { "id": "XP_417366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417366" } ] } ], "protein_names": [ { "name": "Translocase of outer mitochondrial membrane 34", "type": "synonym", "evidence": [ { "id": "A0A8V0ZKZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ6/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial import receptor subunit TOM34", "type": "synonym", "evidence": [ { "id": "XP_417366", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417366" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_417366.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_417366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417366" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TOMM34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ6", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZKZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZKZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "419188", "url": "https://www.ncbi.nlm.nih.gov/gene/419188", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419188", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419188", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ECTTYTN", "url": "https://omabrowser.org/oma/group/ECTTYTN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKZ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZKZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45984", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45984", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45984:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45984:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_417366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_417366", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESAGDLRSAGNEEFRRGQYGAAAELYSRALAVLEDAGEAAAEERSVLLANRAACQLRDGACRGCVADCCSALSLTPFAIKPLLRRAAAYEALESFALAYVDYKTALQVDCSIQAAHDGVNRMTKALLEKHGVNWREKLPPIPTVPIDAQRRWSVPSAGSPTGGAPPGNTPRGDPAQTAAGIERAQTLKEEGNKLVKKGNHKKAIEKYSESLKLNQECATYTNRALCYLTLKQHKEAVQDCTEALRLDPKNVKAFYRRAQALKELKDYKSSIADINSLLKIEPKNTAALRLLQELNRA", "length": 298, "header": "tr|A0A8V0ZKZ6-1|A0A8V0ZKZ6_CHICK Isoform 1 of Translocase of outer mitochondrial membrane 34 OS=Gallus gallus OX=9031 GN=TOMM34 PE=1 SV=1 CANONICAL=A0A8V0ZKZ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ6/entry#A0A8V0ZKZ6-1", "sequence": { "sequence": "MESAGDLRSAGNEEFRRGQYGAAAELYSRALAVLEDAGEAAAEERSVLLANRAACQLRDGACRGCVADCCSALSLTPFAIKPLLRRAAAYEALESFALAYVDYKTALQVDCSIQAAHDGVNRMTKALLEKHGVNWREKLPPIPTVPIDAQRRWSVPSAGSPTGGAPPGNTPRGDPAQTAAGIERAQTLKEEGNKLVKKGNHKKAIEKYSESLKLNQECATYTNRALCYLTLKQHKEAVQDCTEALRLDPKNVKAFYRRAQALKELKDYKSSIADINSLLKIEPKNTAALRLLQELNRA", "length": 298, "header": "tr|A0A8V0ZKZ6-1|A0A8V0ZKZ6_CHICK 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040557933", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040557933" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1QTNF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMW0", "locus": { "chromosome": "5", "start_pos": 22319359, "end_pos": 22263042, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021945", "url": "https://www.ensembl.org/id/ENSGALG00010021945" } ] } } ], "crossref": [ { "id": "A0A8V0ZMW0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMW0", "database": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZL81-1", "uniprot_ac": "A0A8V0ZL81", "uniprot_id": "A0A8V0ZL81_CHICK", "mass": { "chemical_mass": 126263.0, "monoisotopic_mass": 126263.0 }, "refseq": { "ac": "XP_004941447", "name": "DENN domain-containing protein 2B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941447" }, "gene_names": [ { "name": "DENND2B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZL81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL81" } ] }, { "name": "DENND2B", "type": "synonym", "evidence": [ { "id": "XP_004941447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941447" } ] } ], "protein_names": [ { "name": "DENN domain containing 2B", "type": "synonym", "evidence": [ { "id": "A0A8V0ZL81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL81/entry#names_and_taxonomy" } ] }, { "name": "DENN domain-containing protein 2B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004941447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941447" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004941447.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941447" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL81" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DENND2B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL81", "locus": { "chromosome": "5", "start_pos": 9403426, "end_pos": 9253673, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020602", "url": "https://www.ensembl.org/id/ENSGALG00010020602" } ] } } ], "crossref": [ { "id": "A0A8V0ZL81", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZL81", "database": "AlphaFoldDB", "categories": [] }, { "id": "423055", "url": "https://www.ncbi.nlm.nih.gov/gene/423055", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423055", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423055", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDKRDAG", "url": "https://omabrowser.org/oma/group/MDKRDAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL81", "url": "https://www.orthodb.org/?gene=A0A8V0ZL81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004941447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941447", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTMTANKNANINSRAGGSKVPRDSLDRCQSVSPPPLLSPPRSPAYPLSDSEDSCHSTRLTKASGSRLRLKDWSSRTSALHSTSTSPSDTDSPSHPLKAVSVGALDKRLSVFKAEDQKESPKEAQDGDAIGSHPLARSTLSLGTAVNLRNLSLSRTSVRSQVLDIRQKITEWECRREPSPRMSTCVDKRDAGERSGSESCPSVLTSPCSDKTFDFKGFRRMSRTFSECSYPETEEEELLDRDSCHRVEKRPGRSDLPSAAFLKGHMRKESSAVLNRIQKIEQALKEQPGRGLPQLPSSCYSVDKGRKKSLSAVEGLSENLSNSKGGSVILGSEPETPTEAEISSKTKQGVTSNSADPKLLLESSANAVVNPVPKPKRTFEYEADKTHKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRQKKDSRFHRKSQNRKSFEFEDASSLQSLYPSSPTENGTESQHKFGSKSTLEENAYEDIVGESSKENPYEDVELKGRHAGRKSHQLSENSLDSLHRMWTPQDRKYTSPPQLPSKPSSQSLRVGNWSERKTHRLPRLPKRHSHDDMLLLAQLGIPSSPSSLNEDSLSTASELLSTRRARRIPKLVQRINSIYSAKRGKKRLKKLSMSNIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELIEWQERELFEYFVVVSLKKKPSKNTYLPEVTYQFPKLERPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYNSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFDLFSKILDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVIELRRPMDSRLEHVDFECLFKCLSVRQIIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPSSMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELINQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQNEKGERVFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGVNKFLRGLGNKMKFLHKKN", "length": 1120, "header": "tr|A0A8V0ZL81-1|A0A8V0ZL81_CHICK Isoform 1 of DENN domain containing 2B OS=Gallus gallus OX=9031 GN=DENND2B PE=1 SV=1 CANONICAL=A0A8V0ZL81-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZL81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL81/entry#A0A8V0ZL81-1", "sequence": { "sequence": "MTMTANKNANINSRAGGSKVPRDSLDRCQSVSPPPLLSPPRSPAYPLSDSEDSCHSTRLTKASGSRLRLKDWSSRTSALHSTSTSPSDTDSPSHPLKAVSVGALDKRLSVFKAEDQKESPKEAQDGDAIGSHPLARSTLSLGTAVNLRNLSLSRTSVRSQVLDIRQKITEWECRREPSPRMSTCVDKRDAGERSGSESCPSVLTSPCSDKTFDFKGFRRMSRTFSECSYPETEEEELLDRDSCHRVEKRPGRSDLPSAAFLKGHMRKESSAVLNRIQKIEQALKEQPGRGLPQLPSSCYSVDKGRKKSLSAVEGLSENLSNSKGGSVILGSEPETPTEAEISSKTKQGVTSNSADPKLLLESSANAVVNPVPKPKRTFEYEADKTHKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRQKKDSRFHRKSQNRKSFEFEDASSLQSLYPSSPTENGTESQHKFGSKSTLEENAYEDIVGESSKENPYEDVELKGRHAGRKSHQLSENSLDSLHRMWTPQDRKYTSPPQLPSKPSSQSLRVGNWSERKTHRLPRLPKRHSHDDMLLLAQLGIPSSPSSLNEDSLSTASELLSTRRARRIPKLVQRINSIYSAKRGKKRLKKLSMSNIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELIEWQERELFEYFVVVSLKKKPSKNTYLPEVTYQFPKLERPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYNSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFDLFSKILDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVIELRRPMDSRLEHVDFECLFKCLSVRQIIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPSSMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELINQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQNEKGERVFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGVNKFLRGLGNKMKFLHKKN", "length": 1120, "header": "tr|A0A8V0ZL81-1|A0A8V0ZL81_CHICK Isoform 1 of DENN domain containing 2B OS=Gallus gallus OX=9031 GN=DENND2B PE=1 SV=1 CANONICAL=A0A8V0ZL81-1" }, "locus": { "chromosome": "5", "start_pos": 9402621, "end_pos": 9321469, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049722.1", "url": "https://www.ensembl.org/id/ENSGALT00010049722.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029380.1", "url": "https://www.ensembl.org/id/ENSGALP00010029380.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 337, "start_aa": "Thr", "end_pos": 337, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr337", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 409, "start_aa": "Thr", "end_pos": 409, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr409", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423055", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423055", "resource": "KEGG Pathway" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "P78524-1", "protein_name": "DENN domain-containing protein 2B", "gene_name": "DENND2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTMTANKNSSITHGAGGTKAPRGTLSRSQSVSPPPVLSPPRSPIYPLSDSETSACRYPSHSSSRVLLKDRHPPAPSPQNPQDPSPDTSPPTCPFKTASFGYLDRSPSACKRDAQKESVQGAAQDVAGVAACLPLAQSTPFPGPAAGPRGVLLTRTGTRAHSLGIREKISAWEGRREASPRMSMCGEKREGSGSEWAASEGCPSLGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEGEALPVRDSFYRLEKRLGRSEPSAFLRGHGSRKESSAVLSRIQKIEQVLKEQPGRGLPQLPSSCYSVDRGKRKTGTLGSLEEPAGGASVSAGSRAVGVAGVAGEAGPPPEREGSGSTKPGTPGNSPSSQRLPSKSSLDPAVNPVPKPKRTFEYEADKNPKSKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQSRKSFEFEDASSLQSLYPSSPTENGTENQPKFGSKSTLEENAYEDIVGDLPKENPYEDVDLKSRRAGRKSQQLSENSLDSLHRMWSPQDRKYNSPPTQLSLKPNSQSLRSGNWSERKSHRLPRLPKRHSHDDMLLLAQLSLPSSPSSLNEDSLSTTSELLSSRRARRIPKLVQRINSIYNAKRGKKRLKKLSMSSIETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN", "length": 1137 }, "evidence": [ { "id": "A0A8V0ZL81", "url": "https://omabrowser.org/oma/group/A0A8V0ZL81/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q924W7-1", "protein_name": "DENN domain-containing protein 2B", "gene_name": "Dennd2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMTANKNSSITHGTGGTKAPRETLSRSQSVSPPPVLYPPRSPIYPLSDSETSACRYPSHSKSQVLLKDRHSRNPSLLGQDPSPETSPPICTLKATSFSYLDRTPSLRKREDQKETVQGAVQDVEGVAACLPLAQSTPFLGAGSRSVLLSCTGTRAHSLGIREKISAWEGRREASPRMSLCGEKREGPGSEWSVSEGCPSVGCPSVVPSPCSSEKTFDFKGLRRMSRTFSECSYPETEEEAEALPGRDSLYRLEKRPGRTEPSALLRGHGIRKESSAVLSRIQKIEQALKEQPGRGLPQLPSSCYSVDQGRRKTGTLGTLEEPTGTASVSPSSRAGGVAGVAGEAGPPLDREGSASMKSETPGNSSSPQLLPPKSSPDPAVNPVPKPKRTFEYEADKNPKTKPSNGLPPSPTPAAPPPLPSTPAPPVTRRPKKDMRGHRKSQNRKSFEFEDASSLQSLYPSSPTENGTESQPKFGSKSTLEENAYEDIVGGLPKENPYEDVDLKNRRAGRKSQQLSENSLDSLHRMWSPQDRKYNHPPMQLSLKSNSQSLRSGNWSERKSHRLPRLPKRHSHDDMMLLAQLSLPSSPSSLNEDSLSTTSELLSSRRSRRIPKLVQRINSIYNAKRGKKRLKKLSMSSLETASLRDENSESESDSDDRFKAHTQRLVHIQSMLKRAPSYRTLELELLEWQERELFEYFVVVSLKKKPSRNTYLPEVSYQFPKLDRPTKQMREAEERLKAIPQFCFPDAKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLPSGKGPRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALERKSELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTHSEKGERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGLFEQRVEQYLEELPDTEQSGMNKFLRGLGNKMKFLHKKN", 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GN= PE=3 SV=1 CANONICAL=A0A8V0ZLA7-1" }, "locus": { "chromosome": "10", "start_pos": 726137, "end_pos": 725823, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053468.1", "url": "https://www.ensembl.org/id/ENSGALT00010053468.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032223.1", "url": "https://www.ensembl.org/id/ENSGALP00010032223.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 42, "start_aa": "Thr", "end_pos": 42, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr42", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ 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protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZLA8-1" }, "locus": { "chromosome": "3", "start_pos": 21883221, "end_pos": 21838580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010049767.1", "url": "https://www.ensembl.org/id/ENSGALT00010049767.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029407.1", "url": "https://www.ensembl.org/id/ENSGALP00010029407.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLC6-1", "uniprot_ac": "A0A8V0ZLC6", "uniprot_id": "A0A8V0ZLC6_CHICK", "mass": { "chemical_mass": 15304.0, "monoisotopic_mass": 15304.0 }, "refseq": { "ac": "XP_040506723", "name": "TP53-target gene 5 protein isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506723" }, "gene_names": [ { "name": "TP53TG5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC6" } ] }, { "name": "TP53TG5", "type": "synonym", "evidence": [ { "id": "XP_040506723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506723" } ] } ], "protein_names": [ { "name": "TP53 target 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC6/entry#names_and_taxonomy" } ] }, { "name": "TP53-target gene 5 protein isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040506723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506723" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506723" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TP53TG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC6", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZLC6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "419181", "url": "https://www.ncbi.nlm.nih.gov/gene/419181", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HNCAMAT", "url": "https://omabrowser.org/oma/group/HNCAMAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLC6", "url": "https://www.orthodb.org/?gene=A0A8V0ZLC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15902:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15902:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15056", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15056", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040506723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506723", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRQWGTAALLVALGHLAMLLASSTACSNVYRRVSDCVLKLGESMATYGEEDSMELQGLRRVCGYWDEFHACALTALWECQKEAAAIWEMLRKESRKIKFQGSLFDLCSPSTAQSSAWPCVPNVSVLSIPLIITWLNL", "length": 138, "header": "tr|A0A8V0ZLC6-1|A0A8V0ZLC6_CHICK Isoform 1 of TP53 target 5 OS=Gallus gallus OX=9031 GN=TP53TG5 PE=3 SV=1 CANONICAL=A0A8V0ZLC6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC6/entry#A0A8V0ZLC6-1", "sequence": { "sequence": "MGRQWGTAALLVALGHLAMLLASSTACSNVYRRVSDCVLKLGESMATYGEEDSMELQGLRRVCGYWDEFHACALTALWECQKEAAAIWEMLRKESRKIKFQGSLFDLCSPSTAQSSAWPCVPNVSVLSIPLIITWLNL", "length": 138, "header": "tr|A0A8V0ZLC6-1|A0A8V0ZLC6_CHICK Isoform 1 of TP53 target 5 OS=Gallus gallus OX=9031 GN=TP53TG5 PE=3 SV=1 CANONICAL=A0A8V0ZLC6-1" }, "locus": { "chromosome": "20", "start_pos": 5459038, "end_pos": 5456360, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052701.1", "url": "https://www.ensembl.org/id/ENSGALT00010052701.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031607.1", "url": "https://www.ensembl.org/id/ENSGALP00010031607.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC6" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuron projection extension", "id": "GO:1990138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990138", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLD2-1", "uniprot_ac": "A0A8V0ZLD2", "uniprot_id": "A0A8V0ZLD2_CHICK", "mass": { "chemical_mass": 51478.0, "monoisotopic_mass": 51478.0 }, "refseq": { "ac": "XP_015143899", "name": "AMSH-like protease", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143899" }, "gene_names": [ { "name": "STAMBPL1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" } ] }, { "name": "STAMBPL1", "type": "synonym", "evidence": [ { "id": "XP_015143899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143899" } ] } ], "protein_names": [ { "name": "AMSH-like protease", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2/entry#names_and_taxonomy" } ] }, { "name": "AMSH-like protease", "type": "synonym", "evidence": [ { "id": "XP_015143899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143899" } ] }, { "name": "STAM-binding protein-like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015143899.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143899" } ] }, { "annotation": "Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Acts as a positive regulator of the TORC1 signaling pathway by mediating 'Lys-63'-linked deubiquitination of SESN2, thereby inhibiting SESN2-interaction with the GATOR2 complex. Does not cleave 'Lys-48'-linked polyubiquitin chains.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2#function" }, { "database": "UniProtKB", "id": "ARBA00058830", "url": "https://www.uniprot.org/uniprotkb/ARBA00058830#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "STAMBPL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2", "locus": { "chromosome": "6", "start_pos": 19993568, "end_pos": 19973766, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022022", "url": "https://www.ensembl.org/id/ENSGALG00010022022" } ] } } ], "crossref": [ { "id": "A0A8V0ZLD2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859108", "url": "https://www.ncbi.nlm.nih.gov/gene/100859108", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859108", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859108", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QHKNKCK", "url": "https://omabrowser.org/oma/group/QHKNKCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLD2", "url": "https://www.orthodb.org/?gene=A0A8V0ZLD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12947", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12947", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12947:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12947:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01398", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01398", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689901", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689901", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015143899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143899", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEALEKKSDLLGLQTEGNMEQPFSISSLKKLVAIPDHTDISVTPEERVRALSKLGSNIAINEDITPRRYFRSGVEMERMASIYMEEGNLENAFVFYNKFITLFVEKLPSHRDYHQCAVPEKQVIIKKLKEVAFPRTDELKRDLLKKYSLEYQEYMQNKNKCRTESLKKLEQQKLIEAEKKRIAHMRQQQLESEQFQFFEDQLKKQELARDQKIKESMVMSEQIDGSMLSCISVPENSSSPTTLLEKKEKSGMCVSTGDSPPVNRALKPAAALSAVQTQLAEALRGVILPRDLCHKFLLLAEANTLRGIETCGILCGKLTHNEFTITHVIVPKQSSGPDYCDMENVEELFGIQDQFDLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHNDTGIFRLTNAGMLEVSACKKKGFHPHTKDPRLFNPCTHVVGKDIKIIVLDLR", "length": 453, "header": "tr|A0A8V0ZLD2-1|A0A8V0ZLD2_CHICK Isoform 1 of AMSH-like protease OS=Gallus gallus OX=9031 GN=STAMBPL1 PE=3 SV=1 CANONICAL=A0A8V0ZLD2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2/entry#A0A8V0ZLD2-1", "sequence": { "sequence": "MEALEKKSDLLGLQTEGNMEQPFSISSLKKLVAIPDHTDISVTPEERVRALSKLGSNIAINEDITPRRYFRSGVEMERMASIYMEEGNLENAFVFYNKFITLFVEKLPSHRDYHQCAVPEKQVIIKKLKEVAFPRTDELKRDLLKKYSLEYQEYMQNKNKCRTESLKKLEQQKLIEAEKKRIAHMRQQQLESEQFQFFEDQLKKQELARDQKIKESMVMSEQIDGSMLSCISVPENSSSPTTLLEKKEKSGMCVSTGDSPPVNRALKPAAALSAVQTQLAEALRGVILPRDLCHKFLLLAEANTLRGIETCGILCGKLTHNEFTITHVIVPKQSSGPDYCDMENVEELFGIQDQFDLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHNDTGIFRLTNAGMLEVSACKKKGFHPHTKDPRLFNPCTHVVGKDIKIIVLDLR", "length": 453, "header": "tr|A0A8V0ZLD2-1|A0A8V0ZLD2_CHICK Isoform 1 of AMSH-like protease OS=Gallus gallus OX=9031 GN=STAMBPL1 PE=3 SV=1 CANONICAL=A0A8V0ZLD2-1" }, "locus": { "chromosome": "6", "start_pos": 19993300, "end_pos": 19983359, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053520.1", "url": "https://www.ensembl.org/id/ENSGALT00010053520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032247.1", "url": "https://www.ensembl.org/id/ENSGALP00010032247.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100859108", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859108", "resource": "KEGG Pathway" }, { "id": "R-GGA-5689901", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689901", "resource": "Reactome", "description": "Metalloprotease DUBs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V134-1", "protein_name": "AMSH-like protease", "gene_name": "STAMBPL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQPFTVNALRKLAAMPDHTDVSLSPEERVRALSKLGCNITINEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPSHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKKDLLKKYNIQYQEYLQSKNKYKAEVLKKLEHQRLIEAERKRVAQMRQQQLESEQFLFFEDQLKKQELARGQMRSQETPALSEQTDGSALSCFSTHQNNSLLDVFADQPNKSDATNYAGHSPPVNRALKPAATLSAGQNLVVEGLRYVVLSRDLCHRFLLLAESNTVRGIETCGILCGKLTHNEFTITHLIVPKQSAGPDYCDVENVEELFSVQDQHDLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTDAGMLEVSACKKKGFHPHTKDPRLFSICKHVLVKDIKIIVLDLR", "length": 436 }, "evidence": [ { "id": "A0A8V0ZLD2", "url": "https://omabrowser.org/oma/group/A0A8V0ZLD2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2LTP6-1", "protein_name": "AMSH-like protease", "gene_name": "Stambpl1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEQPFTVNSLKKLAAMPDHTDVSLSPEERVRALSKLGCNISINEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPSHRDYQQCEVPEKQDIMKKLKETAFPRTDELKKDLLRKYNTEYQEYLQSENKYKAEILKKLEHQRLIEAERKRIAQMRQQQLESEQFLFFEDQLKKQELARGQMRGQDSAVLSEQTDGSSLSCFSTHQNNSLQNVFADQPPKSDGSDLADHSPPVNRALKPAATLSAVQNLVVEGLRCVVLSRDLCHKFLLLAESNTVRGIETCGILCGKLTHNEFTITHVIVPKQSAGPDYCDVENVEELFSVQDQHGLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVCTCKKKGFHPHTKDPRLFSVCSHVLVKDIKTILLDLR", "length": 436 }, "evidence": [ { "id": "A0A8V0ZLD2", "url": "https://omabrowser.org/oma/group/A0A8V0ZLD2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I5ZXJ2-1", "protein_name": "AMSH-like protease", "gene_name": "Stambpl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQPFTVNSLKKLAAMPDHTDVSLSPEERVRALSKLGCNISINEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPSHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKTDLLRKYNIEYQEYLQSKNKYKAEILKKLEHQRLIEAERQRIAQMRQQQLESEQFLFFEDQLKKQELARGQTRGQDSLVLSEQTDGSGLSCFSTHQNNSLRNVFADHPQKSDVCDLANYSPPVNRALKPAATLSAVQNLVVEGLRCVVLSRDLCHKFLLLADSNTVRGIETCGILCGKLTHNEFTITHVVVPKQSAGPDYCDVENVEELFSVQDQHGLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSTCKKKGFHPHTKDPKLFSICSHVLVKDIKTTVLDLR", "length": 436 }, "evidence": [ { "id": "A0A8V0ZLD2", "url": "https://omabrowser.org/oma/group/A0A8V0ZLD2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3AYE4-1", "protein_name": "AMSH-like protease isoform X1", "gene_name": "stambpl1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDQGFSFSTLKKLAAEPDHTDVTLPAVERVRALSKMGYNIEINEDIAPRRYFRSGVEMERMAAVYLEEGSLENAFVLYNKFITLFVEKLPSHRDYQQCNIPEKQVIMKKLQEVAFPRKDQLKRLLHEKYSKEHSEYLKSQTQAMAVDMCGAQLQKMSMLEEERQRVAQLRKMQIESEQFRYFEDQLRRQELASRRDDAGPKVPEQTDGSCLSQTPRNHVRLDPNRNKPAAPIPKPAATLAAVQNQRVEGLRRVLIPRDLTYRFLLLADSNTARGIETCGVLCGKLTHNEFVLTHVIVPKQSAGPDYCDMENVEELFSYQDHHNLLTLGWIHTHPTQTAFLSSVDLHTHSSYQLMLPEAIAIVCAPKHNESFPAHQCWNGRSGRMQIERFSPPLERPSSVHYLQAHCGERLKNDSPGPQVTEEDGKYQYQQTIENFYLYLSLLEGFFVFIYFTKRYCDRTPQLRCLL", "length": 466 }, "evidence": [ { "id": "A0A8V0ZLD2", "url": "https://omabrowser.org/oma/group/A0A8V0ZLD2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q76N33-1", "protein_name": "AMSH-like protease", "gene_name": "Stambpl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQPFTVNSLKKLAAMPDHTDVSLSPEERVRALSKLGCNISINEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPSHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKTDLLRKYNIEYQEYLQSKNKYKAEILKKLEHQRLIEAERQRIAQMRQQQLESEQFLFFEDQLKKQELARGQIRGQDSPVLSEQTDGSALSCFSTHQSNSLRNAFADHPHKSDGSNFANYSPPVNRALKPAATLSAVQNLVVEGLRCVVLSRDLCHKFLLLADSNTVRGIETCGILCGKLTHNEFTITHVVVPKQSAGPDYCDVENVEELFNVQDQHGLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSTCKKKGFHPHTKDPKLFSICSHVLVKDIKTTVLDLR", "length": 436 }, "evidence": [ { "id": "A0A8V0ZLD2", "url": "https://omabrowser.org/oma/group/A0A8V0ZLD2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96FJ0-1", "protein_name": "AMSH-like protease", "gene_name": "STAMBPL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQPFTVNSLKKLAAMPDHTDVSLSPEERVRALSKLGCNITISEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPNHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKNDLLKKYNVEYQEYLQSKNKYKAEILKKLEHQRLIEAERKRIAQMRQQQLESEQFLFFEDQLKKQELARGQMRSQQTSGLSEQIDGSALSCFSTHQNNSLLNVFADQPNKSDATNYASHSPPVNRALTPAATLSAVQNLVVEGLRCVVLPEDLCHKFLQLAESNTVRGIETCGILCGKLTHNEFTITHVIVPKQSAGPDYCDMENVEELFNVQDQHDLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSACKKKGFHPHTKEPRLFSICKHVLVKDIKIIVLDLR", "length": 436 }, "evidence": [ { "id": "A0A8V0ZLD2", "url": "https://omabrowser.org/oma/group/A0A8V0ZLD2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" } ], "pmid": "" }, { "name": "cellular response to L-leucine", "id": "GO:0071233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" } ], "pmid": "" }, { "name": "K63-linked deubiquitinase activity", "id": "GO:0061578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061578", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" } ], "pmid": "" }, { "name": "metal-dependent deubiquitinase activity", "id": "GO:0140492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140492", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD2" }, { "id": "PS50249", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MPN", "eco_id": "ECO_0000259", "start_pos": 286, "end_pos": 414, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 401, "end_pos": 403 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLD3-1", "uniprot_ac": "A0A8V0ZLD3", "uniprot_id": "A0A8V0ZLD3_CHICK", "mass": { "chemical_mass": 48762.0, "monoisotopic_mass": 48762.0 }, "refseq": {}, "gene_names": [ { "name": "CCDC113", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3" } ] } ], "protein_names": [ { "name": "Cilia- and flagella-associated protein 263", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC113", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZLD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR025254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLD3", "url": "https://www.orthodb.org/?gene=A0A8V0ZLD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUN6", "url": "https://www.orthodb.org/?gene=A0A8V0ZUN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15654", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15654", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15654:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15654:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13870", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13870", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZLD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTREAPGRQQAEKQKKPIDGRWKLREPSLPSPPSVPPPHPVPPLPGRAMAEQELAALPLPQLRDRLEQKRHANDLLRARVELFENQYNKMQLSSLTPPQHGSPPELVPILTRGRSRSRLRSSSSAYFAALTVEQKCELAEREMLDVKSDIQKMEEDSVKTLHDLEAVIQEADAWWADVKKVVSDFEEDIVRTISNKKGSITASEKLLRYLEEKNHQRDLMRQKLRLESNLLRSYKKKLQQQLRQKEHVGEVFHEVHAELLQVKKAQCEEEIDEKNKELQQLKLALEKIQVINFWKKKLHNAMETSTVLMKDISQRKEMLEKIEINTTLVKEQQAKEESLIGWLQKQLSDYSTPPVMSYMQTVMAVADLEKSIKAWERRVAIAEVREMGPGAGWVLSPAALLQAVLEALPVGCSLPPEQRLNFNN", "length": 425, "header": "tr|A0A8V0ZLD3-1|A0A8V0ZLD3_CHICK Isoform 1 of Cilia- and flagella-associated protein 263 OS=Gallus gallus OX=9031 GN=CCDC113 PE=3 SV=1 CANONICAL=A0A8V0ZLD3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3/entry#A0A8V0ZLD3-1", "sequence": { "sequence": "MGTREAPGRQQAEKQKKPIDGRWKLREPSLPSPPSVPPPHPVPPLPGRAMAEQELAALPLPQLRDRLEQKRHANDLLRARVELFENQYNKMQLSSLTPPQHGSPPELVPILTRGRSRSRLRSSSSAYFAALTVEQKCELAEREMLDVKSDIQKMEEDSVKTLHDLEAVIQEADAWWADVKKVVSDFEEDIVRTISNKKGSITASEKLLRYLEEKNHQRDLMRQKLRLESNLLRSYKKKLQQQLRQKEHVGEVFHEVHAELLQVKKAQCEEEIDEKNKELQQLKLALEKIQVINFWKKKLHNAMETSTVLMKDISQRKEMLEKIEINTTLVKEQQAKEESLIGWLQKQLSDYSTPPVMSYMQTVMAVADLEKSIKAWERRVAIAEVREMGPGAGWVLSPAALLQAVLEALPVGCSLPPEQRLNFNN", "length": 425, "header": "tr|A0A8V0ZLD3-1|A0A8V0ZLD3_CHICK Isoform 1 of Cilia- and flagella-associated protein 263 OS=Gallus gallus OX=9031 GN=CCDC113 PE=3 SV=1 CANONICAL=A0A8V0ZLD3-1" }, "locus": { "chromosome": "11", "start_pos": 391554, "end_pos": 388100, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056433.1", "url": "https://www.ensembl.org/id/ENSGALT00010056433.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034176.1", "url": "https://www.ensembl.org/id/ENSGALP00010034176.1" } ] } }, { "isoform_ac": "A0A8V0ZUN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3/entry#A0A8V0ZUN6-1", "sequence": { "sequence": "MGTREAPGRQQAEKQKKPIDGRWKLREPSLPSPPSVPPPHPVPPLPGRAMAEQELAALPLPQLRDRLEQKRHANDLLRARVELFENQYNKMQLSSLTPPQHGSPPELVPILTRGRSRSRLRSSSSAYFAALTVEQKCELAEREMLDVKSDIQKMEEDSVKTLHDLEAVIQEADAWWADVKKVVSDFEEDIVRTISNKKGSITASEKLLRYLEEKNHQRDLMRQKLRLESNLLRSYKKKLQQQLRQKEHVGEVFHEVHAELLQVKKAQCEEEIDEKNKELQQLKLALEKIQVINFWKKKLHNAMETSTVLMKDISQRKEMLEKIEINTTLVKEQQAKEESLIGWLQKQLSDYSTPPVMSYMQTVMAVADLEKSIKAWERRVAIAEMTLQSYHRAWNQVRMSGNLHLPCVMLHGKQ", "length": 414, "header": "tr|A0A8V0ZUN6-1|A0A8V0ZLD3_CHICK Computationally mapped isoform of Cilia- and flagella-associated protein 263 OS=Gallus gallus OX=9031 GN=CCDC113 PE=3 SV=1 CANONICAL=A0A8V0ZLD3-1" }, "locus": { "chromosome": "11", "start_pos": 391554, "end_pos": 387521, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056430.1", "url": "https://www.ensembl.org/id/ENSGALT00010056430.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034174.1", "url": "https://www.ensembl.org/id/ENSGALP00010034174.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3" } ], "pmid": "" }, { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD3" }, { "id": "PF13870", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13870" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCDC113/CCDC96 coiled-coil", "eco_id": "ECO_0000259", "start_pos": 221, "end_pos": 386, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLE5-1", "uniprot_ac": "A0A8V0ZLE5", "uniprot_id": "A0A8V0ZLE5_CHICK", "mass": { "chemical_mass": 77694.0, "monoisotopic_mass": 77694.0 }, "refseq": {}, "gene_names": [ { "name": "LOC121107673", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE5" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE5/entry#names_and_taxonomy" } ] } ], 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21047", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21047", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZLE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHALCSVIKQKVMLTFADMSTVETALEGKTESILNSCFNSVFFLPPELDVPEEEQTLYTKTMIAMNVMLRALVHNCPSSRMREEMCSIFQALLHFFHSQHMHVRTRALYGVLRMITDFIEKDWYCAANCGFIYESLIEVYFPILGQLLGHLCLFSCGQHATRVPATDALYRLYAFVKRDRRTALTEEMEKYVHLREKLQDTNFACDNLCSPSDCAKAFGGYLRPAERMDVVLTALEAMVDSSIYDKEVACSVMAVAMEDHAFWLSDKTQIVTSIRKNLRSITAKAARHCLDSLLLLLTSQMPAEEVRDLLKSSPPSDSSALDMWEVMLCMPRTLEKVLKELTKGSQLSRLLEGVTEDTCILFLALMAKSEDNEDFLGDLRHLKTYLKHPSVEMRTVVLRGLVILSETREKARKMEVVLPEIMATLQAASADVKMKALFVIQNIMGHVKRKEASSIAVQHAEELLPLFVDESSAVRVSSIRLYRDMVQAVVWCHRRRMKGTVRRGLVPLLFRMSDENQDVAQHAGKRLPALPRGGQCRLSFLGPQCHLPASASLQAAGRAVVQTANLLSWNDLRELAEKQETWRIAECLLQRDQSRAEEYLQQSQPYLQDPQGALREEAVRFIGLAARYSRDQSEEKLEDIIRALMPLASDAESSVQCLAAQTTLILRTASRTATSRRSLRALCCLFC", "length": 687, "header": "tr|A0A8V0ZLE5-1|A0A8V0ZLE5_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC121107673 PE=4 SV=1 CANONICAL=A0A8V0ZLE5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE5/entry#A0A8V0ZLE5-1", "sequence": { "sequence": "MHALCSVIKQKVMLTFADMSTVETALEGKTESILNSCFNSVFFLPPELDVPEEEQTLYTKTMIAMNVMLRALVHNCPSSRMREEMCSIFQALLHFFHSQHMHVRTRALYGVLRMITDFIEKDWYCAANCGFIYESLIEVYFPILGQLLGHLCLFSCGQHATRVPATDALYRLYAFVKRDRRTALTEEMEKYVHLREKLQDTNFACDNLCSPSDCAKAFGGYLRPAERMDVVLTALEAMVDSSIYDKEVACSVMAVAMEDHAFWLSDKTQIVTSIRKNLRSITAKAARHCLDSLLLLLTSQMPAEEVRDLLKSSPPSDSSALDMWEVMLCMPRTLEKVLKELTKGSQLSRLLEGVTEDTCILFLALMAKSEDNEDFLGDLRHLKTYLKHPSVEMRTVVLRGLVILSETREKARKMEVVLPEIMATLQAASADVKMKALFVIQNIMGHVKRKEASSIAVQHAEELLPLFVDESSAVRVSSIRLYRDMVQAVVWCHRRRMKGTVRRGLVPLLFRMSDENQDVAQHAGKRLPALPRGGQCRLSFLGPQCHLPASASLQAAGRAVVQTANLLSWNDLRELAEKQETWRIAECLLQRDQSRAEEYLQQSQPYLQDPQGALREEAVRFIGLAARYSRDQSEEKLEDIIRALMPLASDAESSVQCLAAQTTLILRTASRTATSRRSLRALCCLFC", "length": 687, "header": "tr|A0A8V0ZLE5-1|A0A8V0ZLE5_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC121107673 PE=4 SV=1 CANONICAL=A0A8V0ZLE5-1" }, "locus": { "chromosome": "27", "start_pos": 60026, "end_pos": 53929, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053545.1", "url": "https://www.ensembl.org/id/ENSGALT00010053545.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032262.1", "url": "https://www.ensembl.org/id/ENSGALP00010032262.1" } ] } }, { "isoform_ac": "A0A8V0ZNK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE5/entry#A0A8V0ZNK9-1", "sequence": { "sequence": "MSSTVETALEGKTESILNSCFNSVFFLPPELDVPEEEQTLYTKTMIAMNVMLRALVHNCPSSRMREEMCSIFQALLHFFHSQHMHVRTRALYGVLRMITDFIEKDWYCAANCGFIYESLIEVYFPILGQLLGHLCLFSCGQHATRVPATDALYRLYAFVKRDRRTALTEEMEKYVHLREKLQDTNFACDNLCSPSDCAKAFGGYLRPAERMDVVLTALEAMVDSSIYDKEVACSVMAVAMEDHAFWLSDKTQIVTSIRKNLRSITAKAARHCLDSLLLLLTSQMPAEEVRDLLKSSPPSDSSALDMWEVMLCMPRTLEKVLKELTKGSQLSRLLEGVTEDTCILFLALMAKSEDNEDFLGDLRHLKTYLKHPSVEMRTVVLRGLVILSETREKARKMEVVLPEIMATLQAASADVKMKALFVIQNIMGHVKRKEASSIAVQHAEELLPLFVDESSAVRVSSIRLYRDMVQAVVWCHRRRMKGTVRRGLVPLLFRMSDENQDVAQAAGRAVVQTANLLSWNDLRELAEKQETWRIAECLLQRDQSRAEEYLQQSQPYLQDPQGALREEAVRFIGLAARYSRDQSEEKLEDIIRALMPLASDAESSVQCLAAQTTLILRTASRTATSRRSLRALCCLFC", "length": 637, "header": "tr|A0A8V0ZNK9-1|A0A8V0ZNK9_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN=LOC121107673 PE=4 SV=1 CANONICAL=A0A8V0ZLE5-1" }, "locus": { "chromosome": "27", "start_pos": 60198, "end_pos": 53929, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053559.1", "url": "https://www.ensembl.org/id/ENSGALT00010053559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032273.1", "url": "https://www.ensembl.org/id/ENSGALP00010032273.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE5" }, { "id": "PF21047", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21047" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maestro-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 338, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZLE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLE5" }, { "id": "PF23227", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maestro/Maestro-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 379, "end_pos": 523, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLF0-1", "uniprot_ac": "A0A8V0ZLF0", "uniprot_id": "A0A8V0ZLF0_CHICK", "mass": { "chemical_mass": 138062.0, "monoisotopic_mass": 138062.0 }, "refseq": { "ac": "XP_040531758", "name": "ras-associated and pleckstrin homology domains-containing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531758" }, "gene_names": [ { "name": "RAPH1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0" } ] }, { "name": "RAPH1", "type": "synonym", "evidence": [ { "id": "XP_040531758", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531758" } ] } ], "protein_names": [ { "name": "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0/entry#names_and_taxonomy" } ] }, { "name": "ras-associated and pleckstrin homology domains-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040531758", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531758" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052579.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040531758", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531758" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAPH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0", "locus": { "chromosome": "7", "start_pos": 13205319, "end_pos": 13159696, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022033", "url": "https://www.ensembl.org/id/ENSGALG00010022033" } ] } } ], "crossref": [ { "id": "cd01259", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01259", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16136", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16136", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424107", "url": "https://www.ncbi.nlm.nih.gov/gene/424107", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039664", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039664", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039665", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039665", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTFVKYS", "url": "https://omabrowser.org/oma/group/PTFVKYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLF0", "url": "https://www.orthodb.org/?gene=A0A8V0ZLF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLF5", "url": "https://www.orthodb.org/?gene=A0A8V0ZLF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11243:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11243:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040531758", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040531758", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQLSDEELDHGAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDSDKPVAPVKRSPLHQETNLANFSYRFSMYNLNEALNQGETVDLDALMADLCSIEQELSSIGSHSANNTAVKRLATESKVQKPPASRPSTKHGSMKGLSSSSGKVTKPPHANVSLDDITAQLEKASLSMDEAAQQSIAEDAKPVVNAQHRRTASAGTVSDAEVRSISNSSRSSITSAASSMDSLDIDKVTRPQELDLTSQGQPITEHSYLDRETSLLLRNIAGKPSHLLTKEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLMFVERIEKYALFKNPQNYLLGKKETSEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKEDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWINGIRIAKYGKQLYMNYQDALKRTESAYDWTSLSSSSIKSGSSSSSLPESQSNHSNQSDSGVSDTQPTGHVRSQSIVSSMFSEAWKRGTQLEESSKARMEPAGRPFISVAPPVSPQTKVVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQAAPSAASPAAMFVKYSTITRLQNAAQHGGPFSKAPAAAQQPPLPPPSSGKPQILVPPNGVMPPPPPPPPPPTPGSAMAQLKPAPVAPSVPQFTPPPPPPKIHQVQPNISQVAAAAASPLPPPPPPVPAPPPPQAPPKPLMTALPPQPSRKAASPGVSHITSPVPVPLPLAVKKQPTSPQVPPLPQVPPLPPAPPGPTPPPTFPKQQSFSMKPPPSPQSPVPSVVKQIVSQFPPPPTPPATEPQPLKPLPLSVAPQSPPAVKAKPKWQPASAPSPDFPPPPPESSLVFPPPPPSPATSAGSPPPDKSGSPVKKASKTSSPGAKKPPPTPQRNSSIKSTSSTEYSESKRPSVDRLVSKFAHPPEPSGSPSKESSPPVAPPKPGKLNLSGVSLPIVLPQGGIPAKAPAPGVSGKEPMVEFPSPPSDSDFPPPPPEIDLPLPPVEIPSVFSGSTSPKVAVVNPQPQAWSKPSVKKAPPPTRPKRNDSTRLTQADVAESPATPGPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSARMSRAEPTATMDDMALPPPPPELLADQQKTSSFGGSHISGYATLRRGPPPAPPKRDENTKLSRDW", "length": 1284, "header": "tr|A0A8V0ZLF0-1|A0A8V0ZLF0_CHICK Isoform 1 of Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 OS=Gallus gallus OX=9031 GN=RAPH1 PE=1 SV=1 CANONICAL=A0A8V0ZLF0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0/entry#A0A8V0ZLF0-1", "sequence": { "sequence": "MEQLSDEELDHGAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDSDKPVAPVKRSPLHQETNLANFSYRFSMYNLNEALNQGETVDLDALMADLCSIEQELSSIGSHSANNTAVKRLATESKVQKPPASRPSTKHGSMKGLSSSSGKVTKPPHANVSLDDITAQLEKASLSMDEAAQQSIAEDAKPVVNAQHRRTASAGTVSDAEVRSISNSSRSSITSAASSMDSLDIDKVTRPQELDLTSQGQPITEHSYLDRETSLLLRNIAGKPSHLLTKEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLMFVERIEKYALFKNPQNYLLGKKETSEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKEDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWINGIRIAKYGKQLYMNYQDALKRTESAYDWTSLSSSSIKSGSSSSSLPESQSNHSNQSDSGVSDTQPTGHVRSQSIVSSMFSEAWKRGTQLEESSKARMEPAGRPFISVAPPVSPQTKVVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQAAPSAASPAAMFVKYSTITRLQNAAQHGGPFSKAPAAAQQPPLPPPSSGKPQILVPPNGVMPPPPPPPPPPTPGSAMAQLKPAPVAPSVPQFTPPPPPPKIHQVQPNISQVAAAAASPLPPPPPPVPAPPPPQAPPKPLMTALPPQPSRKAASPGVSHITSPVPVPLPLAVKKQPTSPQVPPLPQVPPLPPAPPGPTPPPTFPKQQSFSMKPPPSPQSPVPSVVKQIVSQFPPPPTPPATEPQPLKPLPLSVAPQSPPAVKAKPKWQPASAPSPDFPPPPPESSLVFPPPPPSPATSAGSPPPDKSGSPVKKASKTSSPGAKKPPPTPQRNSSIKSTSSTEYSESKRPSVDRLVSKFAHPPEPSGSPSKESSPPVAPPKPGKLNLSGVSLPIVLPQGGIPAKAPAPGVSGKEPMVEFPSPPSDSDFPPPPPEIDLPLPPVEIPSVFSGSTSPKVAVVNPQPQAWSKPSVKKAPPPTRPKRNDSTRLTQADVAESPATPGPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSARMSRAEPTATMDDMALPPPPPELLADQQKTSSFGGSHISGYATLRRGPPPAPPKRDENTKLSRDW", "length": 1284, "header": "tr|A0A8V0ZLF0-1|A0A8V0ZLF0_CHICK Isoform 1 of Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 OS=Gallus gallus OX=9031 GN=RAPH1 PE=1 SV=1 CANONICAL=A0A8V0ZLF0-1" }, "locus": { "chromosome": "7", "start_pos": 13204315, "end_pos": 13159895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053550.1", "url": "https://www.ensembl.org/id/ENSGALT00010053550.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032267.1", "url": "https://www.ensembl.org/id/ENSGALP00010032267.1" } ] } }, { "isoform_ac": "A0A8V0ZLF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0/entry#A0A8V0ZLF5-1", "sequence": { "sequence": "MEQLSDEELDHGAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDSDKPVAPVKRSPLHQETNLANFSYRFSMYNLNEALNQGETVDLDALMADLCSIEQELSSIGSHSANNTAVKRLATESKVQKPPASRPSTKHGSMKGLSSSSGKVTKPPHANVSLDDITAQLEKASLSMDEAAQQSIAEDAKPVVNAQHRRTASAGTVSDAEVRSISNSSRSSITSAASSMDSLDIDKVTRPQELDLTSQGQPITEEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLMFVERIEKYALFKNPQNYLLGKKETSEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKEDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWINGIRIAKYGKQLYMNYQDALKRTESAYDWTSLSSSSIKSGSSSSSLPESQSNHSNQSDSGVSDTQPTGHVRSQSIVSSMFSEAWKRGTQLEESSKARMEPAGRPFISVAPPVSPQTKVVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQAAPSAASPAAMFVKYSTITRLQNAAQHGGPFSKAPAAAQQPPLPPPSSGKPQILVPPNGVMPPPPPPPPPPTPGSAMAQLKPAPVAPSVPQFTPPPPPPKIHQVQPNISQVAAAAASPLPPPPPPVPAPPPPQAPPKPLMTALPPQPSRKAASPGVSHITSPVPVPLPLAVKKQPTSPQVPPLPQVPPLPPAPPGPTPPPTFPKQQSFSMKPPPSPQSPVPSVVKQIVSQFPPPPTPPATEPQPLKPLPLSVAPQSPPAVKAKPKWQPASAPSPDFPPPPPESSLVFPPPPPSPATSAGSPPPDKSGSPVKKASKTSSPGAKKPPPTPQRNSSIKSTSSTEYSESKRPSVDRLVSKFAHPPEPSGSPSKESSPPVAPPKPGKLNLSGVSLPIVLPQGGIPAKAPAPGVSGKEPMVEFPSPPSDSDFPPPPPEIDLPLPPVEIPSVFSGSTSPKVAVVNPQPQAWSKPSVKKAPPPTRPKRNDSTRLTQADVAESPATPGPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSARMSRAEPTATMDDMALPPPPPELLADQQKTSSFGGSHISGYATLRRGPPPAPPKRDENTKLSRDW", "length": 1259, "header": "tr|A0A8V0ZLF5-1|A0A8V0ZLF5_CHICK Computationally mapped isoform of Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 OS=Gallus gallus OX=9031 GN=RAPH1 PE=1 SV=1 CANONICAL=A0A8V0ZLF0-1" }, "locus": { "chromosome": "7", "start_pos": 13204315, "end_pos": 13159895, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053558.1", "url": "https://www.ensembl.org/id/ENSGALT00010053558.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032272.1", "url": "https://www.ensembl.org/id/ENSGALP00010032272.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1008, "start_aa": "Thr", "end_pos": 1008, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1008", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1178, "start_aa": "Thr", "end_pos": 1178, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1178", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 753, "start_aa": "Thr", "end_pos": 753, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr753", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 878, "start_aa": "Thr", "end_pos": 878, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr878", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 917, "start_aa": "Thr", "end_pos": 917, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr917", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A272-1", "protein_name": "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1", "gene_name": "Raph1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQLSDEEIDHGAEEDSDKEDQDLDKMFGAWLGELDRLTQSLDSDKPKEPVKRSPLRQETNMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSVGSGNSKRQVTEPKVAQKLPASRHTSKHGTLRGVSSSSTRTTRPPHANYSLDDITAQLEQASLSMDEAAQQSAVEDAKPPATNQHRRTASAGTVSDAEVRSVSNSSRSSITSAASSMDSLDIDKVTRPQELDLTAHQGKPITEHATSLSCPSKQAKHHSDFTEEQAQLAPHSYLDRETSLLLRNIAGKPSHLLTKEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGKKETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDCCLALKHPQIQKKSQYIKYLCCDDARTLHQWVNGIRIAKYGKQLYTNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTLPSGHIRSQSTVSSIFSEAWKRGTQLEESSKARMESMNRSYTSLMPPLSPQTKIITPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSSGSAATMFVKYSTITRLQNAAQHSGTLFKSPAPSAMQPLPLASQSKAQIVVPPNGVIPPPPPPPPPPTPGSAMAQLKPVPCAPSLPQFSPQPPPLKIHQVQHLPQAAPPTPPAAPLIPATVPPQAPPKPLVTIPPSASTKMVSPVVAQAVPPTPAPPVPPTKKQPVFPVSHIPPTPPVQPTPHPPPTLPKQQSFGVKPPPSPLSPVPSVVKQMASQFPPPPTPPPVDSQPLKPLPASVTPQSPPAVKAKPKWQPSSIPAPSPDFPPPPPESSLVFPPPPPPAPVPPPPPPPPPPPPPPPVSPMASPTPDKGGSPGKKTSKMSSPGGKKPPPTPQRNSSIKSGSCAEHPEPKRPSVDSLVSKFAPPAESGSPSKETPPPPAAPPKPGKLHLSGVNLPGIHQQGILSAKPSVLSGRGKDAVVEFPSPPSDSDFPPPPPEIELPLPPIEIPAVFSGNTSPKVAVVNPQPQLWSKTSVKKAPPPTRPKRNDSTRLTQADISEQPAMTTVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGFGGSHISGYATLRRGPPPAPPKRDQNTKLSRDW", "length": 1318 }, "evidence": [ { "id": "A0A8V0ZLF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZLF0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3AQ39-1", "protein_name": "Ras-associated and pleckstrin homology domains-containing protein 1b isoform 1", "gene_name": "raph1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEQVSDDELDHAAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDDGRPEKVQKAPLRQETNLANFSYRFSMYNINEAINQGETVDLDALMADLCSIEQELSTIGKPISKTLDGKSKQRPTGRSASAKHSGGGSSGGSTSSSTRASPASTVRGGNSQSRPLASNFSLDDITAQLEKASLSMDEAAKQTSESSSSSYSSANPPSNSHHRRTGSVGTVSDQEVRSIGHSSRSSVNSASASSMDSLDIRGQENETQSQNQSQTSTEHVLLRRANGKTTRRHLDFTSQEGEVDQSTHSYLDRETSLILKNIAGKPSHLLTKEEQAAKAKAEKIRVALEKIKEAQVKKLVIRVHMSDESSKTMMVDERQTVRQLLDSLLDKSHCGYSPDWALVETIPELQMERIFEDHENLVENLLNWTRDSQNKLMFIERIEKYALFKNPQNYLLGRKETSEMADRNKEALLEECFCGSSVSVPEIEGVLWLKEDGKKSWKKRYFLLRASGIYFVPKGKAKASRDLVCFLQLDHVNVYYGQDYRSKYKAPTDYCLALKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYVNYQEAMKRTEAAYDWSSLSSTSIKSGTSSVSIPESQSNHSSQTDSGMSDGTSSSHARSQSVVSSIFSEAWKRGTQIEESTKARPESIRSTHSSHSSHSSHHVSQQQHLHAQQPHVHSILQSRGSVTQAPAQAPTQTLAQAPPQVAPAPPPPPPPPPPPPPPPISSIPHHATPTMFAKYSTITRLQNASQATSHHKPQPQIQQQVPPVPPPSKPQSNNIPSGANIPPPPPPPPPASMPPPGSAMAVLKLGPPAAAVIPQISPSPPSPPPPPPPPPIMPVQSQPQPPPPPIMPMQSQPLPPPPPITPMQSHNLPPPPPMQSHALPPPPPITPMQSHALPPPPPITPMQSHALPPPPPITPMQSHALPPPPPITPMQSHALPPPPPIMPMQSEPLPPPAQIMPMQSHPLPPPPPLVQMQSQPMPPPPPTVSFQSQPLPPPPPPLQANGLPPPPPLITNGLKQAFAHKFPSTPQDVLPPANQNNFPPPPPPPPPPPLAPTLPPYQHVTSTSNPPPPPPPPPPPPPAPIHLANQPAVLPKFFTGGFPPQKAPKPSCGILPVSPVAPALQPPPPPPPPPPPPPPAPLKNQPPPTLPKQHSLSKTLPFSSQTSSVPSMVKQLASQFPVASPALTNQTDSLKAPQSPPAVKVKPKWQPVGQGQQQQRSPEFPPPPPDNALGFASPTPPPPPPPPLPPGPTPPPPPPPPPLMSGSPIKKSPSGSSAGVKKPPPTPQRNSSVKYDASTEYQESRKNLVSKFNPSSASSTTSTSSCSPSKELSAGPQAPPKPGKLNLANLPLALQNKFNQNRQSAADFPSPPPPENDFFPPPPIESDLPPPPPLPGDLNGVSPKVAVVNPQPQPAWGKSSLKKTQPPASLRCNNTVRESPPLSPPSIHGGPIPHSPKGTTQPNFLEDLNKTLKRKSSRVSGDKVDPVATMDDMVLPPPPPELLQDQQRLSGSGFMSGNISGYATLRRGPPPAPPKRDHSTKLTN", "length": 1565 }, "evidence": [ { "id": "A0A8V0ZLF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZLF0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F2Z3U3-1", "protein_name": "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1", "gene_name": "Raph1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"MEQLSDEEIDHGAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDSDKPMEPVKRSPLRQETNMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSIGSGNSKRQITETKATQKLPVSRHTLKHGTLKGLSSSSNRIAKPSHASYSLDDVTAQLEQASLSMDEAAQQSVLEDTKPLVTNQHRRTASAGTVSDAEVHSISNSSHSSITSAASSMDSLDIDKVTRPQELDLTHQGQPITEEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGKKETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQNTKLSRDW", "length": 1250 }, "evidence": [ { "id": "A0A8V0ZLF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZLF0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0" } ], "pmid": "" }, { "name": "cell 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{ "database": "UniProtKB", "id": "A0A8V0ZLF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1012, "end_pos": 1014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1065, "end_pos": 1067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1162, "end_pos": 1164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1202, "end_pos": 1204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 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}, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 578, "end_pos": 580 }, { "start_pos": 581, "end_pos": 583 }, { "start_pos": 64, "end_pos": 66 }, { "start_pos": 788, "end_pos": 790 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLM1-1", "uniprot_ac": "A0A8V0ZLM1", "uniprot_id": "A0A8V0ZLM1_CHICK", "mass": { "chemical_mass": 103207.0, "monoisotopic_mass": 103207.0 }, "refseq": { "ac": "NP_001335876", "name": "NACHT, LRR and PYD domains-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" }, "gene_names": [ { "name": "NLRP3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ] }, { "name": "CIAS1", "type": "synonym", "evidence": [ { "id": "NP_001335876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" } ] }, { "name": "NLRP3", "type": "synonym", "evidence": [ { "id": "NP_001335876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" } ] }, { "name": "NLRPL", "type": "synonym", "evidence": [ { "id": "NP_001335876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" } ] }, { "name": "Nalp3", "type": "synonym", "evidence": [ { "id": "NP_001335876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1/entry#names_and_taxonomy" } ] }, { "name": "NACHT, LRR and PYD domains-containing protein 12", "type": "synonym", "evidence": [ { "id": "NP_001335876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" } ] }, { "name": "NACHT, LRR and PYD domains-containing protein 3", "type": "synonym", "evidence": [ { "id": "NP_001335876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" } ] }, { "name": "NLR family pyrin domain containing-like", "type": "synonym", "evidence": [ { "id": "NP_001335876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" } ] }, { "name": "cold autoinflammatory syndrome 1", "type": "synonym", "evidence": [ { "id": "NP_001335876", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" } ] } ], "function": [ { "annotation": "HgCl2 exposure mediates pyroptosis of HD11 cells and promotes M1 polarization and the release of inflammatory factors through ROS/Nrf2/NLRP3.", "evidence": [ { "database": "RefSeq", "id": "NP_001335876", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" }, { "database": "PubMed", "id": "38056124", "url": "https://glygen.org/publication/PubMed/38056124" } ] }, { "annotation": "Independently of inflammasome activation, regulates the differentiation of T helper 2 (Th2) cells and has a role in Th2 cell-dependent asthma and tumor growth. During Th2 differentiation, required for optimal IRF4 binding to IL4 promoter and for IRF4-dependent IL4 transcription. Binds to the consensus DNA sequence 5'-GRRGGNRGAG-3'. May also participate in the transcription of IL5, IL13, GATA3, CCR3, CCR4 and MAF.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1#function" }, { "database": "UniProtKB", "id": "ARBA00045987", "url": "https://www.uniprot.org/uniprotkb/ARBA00045987#function" } ] }, { "annotation": "That NLRP3 gene is highly variable between mammalian and avian.", "evidence": [ { "database": "RefSeq", "id": "NP_001335876", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" }, { "database": "PubMed", "id": "26246158", "url": "https://glygen.org/publication/PubMed/26246158" } ] }, { "annotation": "The NLRP3 molecule is responsible for mediating the pyroptosis of intestinal mucosa cells and plays a crucial role in salmonellosis enteritis in chicks. Review article", "evidence": [ { "database": "RefSeq", "id": "NP_001335876", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" }, { "database": "PubMed", "id": "38422886", "url": "https://glygen.org/publication/PubMed/38422886" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NLRP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1", "locus": { "chromosome": "5", "start_pos": 625264, "end_pos": 650946, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022058", "url": "https://www.ensembl.org/id/ENSGALG00010022058" } ] } } ], "crossref": [ { "id": "A0A8V0ZLM1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLM1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08321", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08321", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423021", "url": "https://www.ncbi.nlm.nih.gov/gene/423021", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050637", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423021", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423021", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZLJ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZLJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLK2", "url": "https://www.orthodb.org/?gene=A0A8V0ZLK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLM1", "url": "https://www.orthodb.org/?gene=A0A8V0ZLM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45690:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45690:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5689901", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689901", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-844456", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-844456", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001335876", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGEESTILLEALEGLTLEDFQEFKKKLPHTDIKGGWNIGRDELEKVTHPSSLISYMGDSYGEGAAMDIAISLFEEMNQRDLAEKILDEKVKEYKQKYTEHVAREFLQYKEANSCLGENLSVRDRYTNLTIARKSWDQHGDEPGDVSSDTVTTQTLFEPSKDGQVPLITVLVGASGMGKTMTIRKVMMEWVEGTLCTQFDYVFCIDCKELSFSKEVSMVDLISKCCPQQRMPAGRILGNPEKILFIFDSFEALGLPLAQPKDELSTDPTEAKPLETTLLSLLRRTVLPESSVLIATRPAALQSLGQCLEGKHYVEILGFSPAAREEYFHRYFGNDNKADVAFRFTRGNEVLYSLCVIPVMSWTVCTVLERELYERNQLLACSKTTTQMIMFYLSWLMKHRVSNAWQNLQQFLHKLCSLAADGIWKHKVLFEEKEIEDQGLNQPQLLSLFLNEKGLEKGTDHVNVYSFSHLHLQELFAAMFYVLEDQDGMVSDSRILAKDVNMLLESYHTSRMDLNVTVRLLFGLVNPKSVEYAGEGIGCRISLQPREDLLRWLQTRPRGTSHPREVMKIEDLDTFHLLFETNEKSFVQSVLGSFTGIALQDVKLTLYDQAALCFCIKQWAGLLSVTLRSCSFHQQHHRQEPAKGLPRQSWQQEELHSPLHPLCQALGHPGSSLQSLRLQWCGLTEGDSGALGTLLATLPSLVHLELGDGALGDDGVRMLCAGLRQPGCQLRVLRLRYTHLTSACCQDLAVALGTSTCLEELDLSFSAGLRDDGVKLLCEGLQHSGCQLRALRLGSCSLTGACCQALVAWLRHSHGLKCLDLSDTELGAGATLLLQHLRHHSCTLQTLGLSTSTLSKDALQELAALRALKPSLKITDLLEHEAPETGAMARLTFQRSVWAGRGAAVRGRKGLPSSRAAPPHSRSLC", "length": 925, "header": "tr|A0A8V0ZLM1-1|A0A8V0ZLM1_CHICK Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 OS=Gallus gallus OX=9031 GN=NLRP3 PE=3 SV=1 CANONICAL=A0A8V0ZLM1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1/entry#A0A8V0ZLJ1-1", "sequence": { "sequence": "MAGEESTILLEALEGLTLEDFQEFKKKLPHTDIKGGWNIGRDELEKVTHPSSLISYMGDSYGEGAAMDIAISLFEEMNQRDLAEKILDEKVKEYKQKYTEHVAREFLQYKEANSCLGENLSVRDRYTNLTIARKSWDQHGDEPGDVSSDTVTTQTLFEPSKDGQVPLITVLVGASGMGKTMTIRKVMMEWVEGTLCTQFDYVFCIDCKELSFSKEVSMVDLISKCCPQQRMPAGRILGNPEKILFIFDSFEALGLPLAQPKDELSTDPTEAKPLETTLLSLLRRTVLPESSVLIATRPAALQSLGQCLEGKHYVEILGFSPAAREEYFHRYFGNDNKADVAFRFTRGNEVLYSLCVIPVMSWTVCTVLERELYERNQLLACSKTTTQMIMFYLSWLMKHRVSNAWQNLQQFLHKLCSLAADGIWKHKVLFEEKEIEDQGLNQPQLLSLFLNEKGLEKGTDHVNVYSFSHLHLQELFAAMFYVLEDQDGMVSDSRILAKDVNMLLESYHTSRMDLNVTVRLLFGLVNPKSVEYAGEGIGCRISLQPREDLLRWLQTRPRGTSHPREVMKIEDLDTFHLLFETNEKSFVQSVLGSFTGIALQDVKLTLYDQAALCFCIKQWAGLLSVTLRSCSFHQQHHRQEPAKGLPRQSWQQEELHSPLHPLCQALGHPGSSLQSLRLQWCGLTEGDSGALGTLLATLPSLVHLELGDGALGDDGVRMLCAGLRQPGCQLRVLR", "length": 734, "header": "tr|A0A8V0ZLJ1-1|A0A8V0ZLM1_CHICK Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 OS=Gallus gallus OX=9031 GN=NLRP3 PE=3 SV=1 CANONICAL=A0A8V0ZLM1-1" }, "locus": { "chromosome": "5", "start_pos": 629245, "end_pos": 626256, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053643.1", "url": "https://www.ensembl.org/id/ENSGALT00010053643.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032313.1", "url": "https://www.ensembl.org/id/ENSGALP00010032313.1" } ] } }, { "isoform_ac": "A0A8V0ZLK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1/entry#A0A8V0ZLK2-1", "sequence": { "sequence": "MAGEESTILLEALEGLTLEDFQEFKKKLPHTDIKGGWNIGRDELEKVTHPSSLISYMGDSYGEGAAMDIAISLFEEMNQRDLAEKILDEKVKEYKQKYTEHVAREFLQYKEANSCLGENLSVRDRYTNLTIARKSWDQHGDEPGDVSSDTVTTQTLFEPSKDGQVPLITVLVGASGMGKTMTIRKVMMEWVEGTLCTQFDYVFCIDCKELSFSKEVSMVDLISKCCPQQRMPAGRILGNPEKILFIFDSFEALGLPLAQPKDELSTDPTEAKPLETTLLSLLRRTVLPESSVLIATRPAALQSLGQCLEGKHYVEILGFSPAAREEYFHRYFGNDNKADVAFRFTRGNEVLYSLCVIPVMSWTVCTVLERELYERNQLLACSKTTTQMIMFYLSWLMKHRVSNAWQNLQQFLHKLCSLAADGIWKHKVLFEEKEIEDQGLNQPQLLSLFLNEKGLEKGTDHVNVYSFSHLHLQELFAAMFYVLEDQDGMVSDSRILAKDVNMLLESYHTSRMDLNVTVRLLFGLVNPKSVEYAGEGIGCRISLQPREDLLRWLQTRPRGTSHPREVMKIEDLDTFHLLFETNEKSFVQSVLGSFTGIALQDVKLTLYDQAALCFCIKQWAGLLSVTLRSCSFHQQHHRQEPAKEVSPFPLQSKVLERSGMVNASFHPNNTTSLTVGQGGHTHPLLPRAVGQSVLVHLELGDGALGDDGVRMLCAGLRQPGCQLRVLRLGSCSLTGACCQALVAWLRHSHGLKCLDLSDTELGAGATLLLQHLRHHSCTLQTLGLSTSTLSKDALQELAALRALKPSLKITDLLEHEAPETGAMARLTFQRSVWAGRGAAVRGRKGLPSSRAAPPHSRSLC", "length": 860, "header": "tr|A0A8V0ZLK2-1|A0A8V0ZLK2_CHICK Computationally mapped isoform of NLR family pyrin domain containing 3 OS=Gallus gallus OX=9031 GN=NLRP3 PE=4 SV=1 CANONICAL=A0A8V0ZLM1-1" }, "locus": { "chromosome": "5", "start_pos": 629245, "end_pos": 625377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053662.1", "url": "https://www.ensembl.org/id/ENSGALT00010053662.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032323.1", "url": "https://www.ensembl.org/id/ENSGALP00010032323.1" } ] } }, { "isoform_ac": "A0A8V0ZLM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1/entry#A0A8V0ZLM1-1", "sequence": { "sequence": "MAGEESTILLEALEGLTLEDFQEFKKKLPHTDIKGGWNIGRDELEKVTHPSSLISYMGDSYGEGAAMDIAISLFEEMNQRDLAEKILDEKVKEYKQKYTEHVAREFLQYKEANSCLGENLSVRDRYTNLTIARKSWDQHGDEPGDVSSDTVTTQTLFEPSKDGQVPLITVLVGASGMGKTMTIRKVMMEWVEGTLCTQFDYVFCIDCKELSFSKEVSMVDLISKCCPQQRMPAGRILGNPEKILFIFDSFEALGLPLAQPKDELSTDPTEAKPLETTLLSLLRRTVLPESSVLIATRPAALQSLGQCLEGKHYVEILGFSPAAREEYFHRYFGNDNKADVAFRFTRGNEVLYSLCVIPVMSWTVCTVLERELYERNQLLACSKTTTQMIMFYLSWLMKHRVSNAWQNLQQFLHKLCSLAADGIWKHKVLFEEKEIEDQGLNQPQLLSLFLNEKGLEKGTDHVNVYSFSHLHLQELFAAMFYVLEDQDGMVSDSRILAKDVNMLLESYHTSRMDLNVTVRLLFGLVNPKSVEYAGEGIGCRISLQPREDLLRWLQTRPRGTSHPREVMKIEDLDTFHLLFETNEKSFVQSVLGSFTGIALQDVKLTLYDQAALCFCIKQWAGLLSVTLRSCSFHQQHHRQEPAKGLPRQSWQQEELHSPLHPLCQALGHPGSSLQSLRLQWCGLTEGDSGALGTLLATLPSLVHLELGDGALGDDGVRMLCAGLRQPGCQLRVLRLRYTHLTSACCQDLAVALGTSTCLEELDLSFSAGLRDDGVKLLCEGLQHSGCQLRALRLGSCSLTGACCQALVAWLRHSHGLKCLDLSDTELGAGATLLLQHLRHHSCTLQTLGLSTSTLSKDALQELAALRALKPSLKITDLLEHEAPETGAMARLTFQRSVWAGRGAAVRGRKGLPSSRAAPPHSRSLC", "length": 925, "header": "tr|A0A8V0ZLM1-1|A0A8V0ZLM1_CHICK Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 OS=Gallus gallus OX=9031 GN=NLRP3 PE=3 SV=1 CANONICAL=A0A8V0ZLM1-1" }, "locus": { "chromosome": "5", "start_pos": 629245, "end_pos": 625377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053694.1", "url": "https://www.ensembl.org/id/ENSGALT00010053694.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032344.1", "url": "https://www.ensembl.org/id/ENSGALP00010032344.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Tissue-specific expression pattern and histological distribution of NLRP3 in Chinese yellow chicken.", "journal": "Veterinary research communications", "date": "2015-09", "authors": "Ye Jinhui, Yu Meng, Zhang Kaizhao, Liu Jianxin, Wang Qingnan, Tao Pan, Jia Kun, Liao Ming, Ning Zhangyong", "evidence": [ { "database": "RefSeq", "id": "NP_001335876", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" } ], "reference": [ { "type": "PubMed", "id": "26246158", "url": "https://glygen.org/publication/PubMed/26246158" } ] }, { "title": "HgCl2 exposure mediates pyroptosis of HD11 cells and promotes M1 polarization and the release of inflammatory factors through ROS/Nrf2/NLRP3.", "journal": "Ecotoxicology and environmental safety", "date": "2024-01-01", "authors": "Wang Jiaqi, Yin Yilin, Zhang Qirui, Deng Xinrui, Miao Zhiruo, Xu Shiwen", "evidence": [ { "database": "RefSeq", "id": "NP_001335876", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" } ], "reference": [ { "type": "PubMed", "id": "38056124", "url": "https://glygen.org/publication/PubMed/38056124" } ] }, { "title": "The NLRP3 molecule is responsible for mediating the pyroptosis of intestinal mucosa cells and plays a crucial role in salmonellosis enteritis in chicks.", "journal": "Molecular immunology", "date": "2024-04", "authors": "Liu Zhe, Du Juan, Wang Yanhong, Song Haoyu, Lu Ligong, Wu Rui, Jin Chenghao", "evidence": [ { "database": "RefSeq", "id": "NP_001335876", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001335876" } ], "reference": [ { "type": "PubMed", "id": "38422886", "url": "https://glygen.org/publication/PubMed/38422886" } ] } ], "pathway": [ { "id": "gga:423021", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423021", "resource": "KEGG Pathway" }, { "id": "R-GGA-5689901", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689901", "resource": "Reactome", "description": "Metalloprotease DUBs" }, { "id": "R-GGA-844456", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-844456", "resource": "Reactome", "description": "The NLRP3 inflammasome" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" }, { "name": "canonical inflammasome complex", "id": "GO:0061702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061702", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8V0Y005", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y005" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1J8", "gene_name": "YTHDC2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1J8" } ] } ] }, { "uniprot_ac": "A0A8V0Y242", "gene_name": "DDX41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Y242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y242" } ] } ] }, { "uniprot_ac": "A0A8V0YAA4", "gene_name": "XRCC6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A8V0YAA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAA4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YFB8", "gene_name": "ATP13A4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFB8" } ] } ] }, { "uniprot_ac": "A0A8V0YFG2", "gene_name": "ATP13A5", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8V0YFG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFG2" } ] } ] }, { "uniprot_ac": "A0A8V0YGQ1", "gene_name": "DDX59", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGQ1" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YLC1", "gene_name": "DDX11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YLC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLC1" } ] } ] }, { "uniprot_ac": "A0A8V0YLM0", "gene_name": "RECQL", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YLM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLM0" } ] } ] }, { "uniprot_ac": "A0A8V0YNF9", "gene_name": "DDX27", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNF9" } ] } ] }, { "uniprot_ac": "A0A8V0YQS3", "gene_name": "MCM9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0YQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQS3" } ] } ] }, { "uniprot_ac": "A0A8V0YRH6", "gene_name": "ERCC6L", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YRH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRH6" } ] } ] }, { "uniprot_ac": "A0A8V0YT68", "gene_name": "ATRX", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V0YT68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YT68" } ] } ] }, { "uniprot_ac": "A0A8V0YU49", "gene_name": "DHX29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YU49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YU49" } ] } ] }, { "uniprot_ac": "A0A8V0YUC5", "gene_name": "SKIV2L2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUC5" } ] } ] }, { "uniprot_ac": "A0A8V0YUG9", "gene_name": "TDRD9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUG9" } ] } ] }, { "uniprot_ac": "A0A8V0YUW3", "gene_name": "EIF4A2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0YUW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUW3" } ] } ] }, { "uniprot_ac": "A0A8V0Z1F9", "gene_name": "DHX57", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1F9" } ] } ] }, { "uniprot_ac": "A0A8V0Z289", "gene_name": "DDX24", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z289" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z289", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z289" } ] } ] }, { "uniprot_ac": "A0A8V0Z2M8", "gene_name": "MCM8", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M8" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A8V0Z2M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2M8" } ] } ] }, { "uniprot_ac": "A0A8V0Z5P2", "gene_name": "RHOT2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V0Z5P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5P2" } ] } ] }, { "uniprot_ac": "A0A8V0Z655", "gene_name": "SNRNP200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0Z655", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z655" } ] } ] }, { "uniprot_ac": "A0A8V0Z659", "gene_name": "TWNK", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' 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}, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE45" } ] } ] }, { "uniprot_ac": "A0A8V0ZEN5", "gene_name": "DDX19", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZEN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZEN5" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN9", "gene_name": "DDX54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZFN9", "database": "UniProtKB", "url": 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"activity": "", "evidence": [ { "id": "A0A8V0ZUQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUQ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUR5", "gene_name": "DDX6", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUR5" } ] } ] }, { "uniprot_ac": "A0A8V0ZUT3", "gene_name": "DHX58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZUT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZVY2", "gene_name": "RTEL1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A8V0ZVY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY2" } ] } ] }, { "uniprot_ac": "A0A8V0ZWH7", "gene_name": "DHX35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZWH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH7" } ] } ] }, { "uniprot_ac": "A0A8V0ZZF5", "gene_name": "DHX8", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZF5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK3", "gene_name": "SUPV3L1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V0ZZK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK3" } ] } ] }, { "uniprot_ac": "A0A8V1A3M1", "gene_name": "DDX55", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A3M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3M1" } ] } ] }, { "uniprot_ac": "A0A8V1A4V3", "gene_name": "POLQ", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A8V1A4V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V3" } ] } ] }, { "uniprot_ac": "A0A8V1A5D6", "gene_name": "DDX51", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A5D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A5D6" } ] } ] }, { "uniprot_ac": "A0A8V1A712", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A712", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A712" } ] } ] }, { "uniprot_ac": "A0A8V1A7M6", "gene_name": "", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M6" } ] } ] }, { "uniprot_ac": "A0A8V1A7P4", "gene_name": "DDX49", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1A7P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P4" } ] } ] }, { "uniprot_ac": 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"ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "A0A8V1ADZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADZ7" } ] } ] }, { "uniprot_ac": "A0A8V1AE46", "gene_name": "ENTPD8L1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8V1AE46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE46" } ] } ] }, { "uniprot_ac": "A0A8V1AER6", "gene_name": "MOV10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1AER6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AER6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8V1AL41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL41" } ] } ] }, { "uniprot_ac": "A0A8V1ALH0", "gene_name": "RNF213", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V1ALH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ALH0" } ] } ] }, { "uniprot_ac": "B6ZLK2", "gene_name": "CHD1", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "B6ZLK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B6ZLK2" } ] } ] }, { "uniprot_ac": "E1BSC0", 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"ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "E1BY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY42" } ] } ] }, { "uniprot_ac": "F1N8Z4", "gene_name": "RUVBL1", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1N8Z4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N8Z4" } ] } ] }, { "uniprot_ac": "F1N991", "gene_name": "DDX4", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1N991", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N991" } ] } ] }, { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "F1NFJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NFJ0" } ] } ] }, { "uniprot_ac": "F1NHI3", "gene_name": "DHX15", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "F1NHI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NHI3" } ] } ] }, { "uniprot_ac": "F1NN44", "gene_name": "ALPL", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "F1NN44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NN44" } ] } ] }, { "uniprot_ac": "F1NQJ3", "gene_name": "PMS2", "activity": [ { "ec_number": "3.1.-.-", "activity": "", "evidence": [ { "id": "F1NQJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQJ3" } ] } ] }, { "uniprot_ac": "F1NTD6", "gene_name": "ascc3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "F1NTD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTD6" } ] } ] }, { "uniprot_ac": "F1NZ23", "gene_name": "ERCC3", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "F1NZ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NZ23" } ] }, { "ec_number": 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"activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZHZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHZ0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZHZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZHZ0" } ] } ] }, { "uniprot_ac": "Q5ZI74", "gene_name": "DHX30", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZI74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI74" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZI74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZI74" } ] } ] }, { "uniprot_ac": "Q5ZIW1", "gene_name": "TWNK", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "Q5ZIW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW1" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "Q5ZIW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZIW1" } ] } ] }, { "uniprot_ac": "Q5ZJ54", "gene_name": "CCT6", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZJ54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJ54" } ] } ] }, { "uniprot_ac": "Q5ZJF6", "gene_name": "DDX10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "Q5ZJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJF6" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "Q5ZJF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJF6" } ] } ] }, { "uniprot_ac": "Q5ZJK8", "gene_name": "CCT7", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { 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}, "locus": { "chromosome": "20", "start_pos": 5465150, "end_pos": 5463529, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052720.1", "url": "https://www.ensembl.org/id/ENSGALT00010052720.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031626.1", "url": "https://www.ensembl.org/id/ENSGALP00010031626.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6811440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811440", "resource": "Reactome", "description": "Retrograde transport at the Trans-Golgi-Network" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLM3" } ], 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLN8-1", "uniprot_ac": "A0A8V0ZLN8", "uniprot_id": "A0A8V0ZLN8_CHICK", "mass": { "chemical_mass": 20854.0, "monoisotopic_mass": 20854.0 }, "refseq": { "ac": "XP_024999995", "name": "dickkopf-related protein 3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999995" }, "gene_names": [ { "name": "LOC100858629", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8" } ] }, { "name": "LOC100858629", "type": "synonym", "evidence": [ { "id": "XP_024999995", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999995" } ] } ], "protein_names": [ { "name": "Dickkopf N-terminal cysteine-rich domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8/entry#names_and_taxonomy" } ] }, { "name": "dickkopf-related protein 3-like", "type": "synonym", "evidence": [ { "id": "XP_024999995", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999995" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024999995.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999995", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999995" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC100858629", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZLN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100858629", "url": "https://www.ncbi.nlm.nih.gov/gene/100858629", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GPSMCCA", "url": "https://omabrowser.org/oma/group/GPSMCCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLN8", "url": "https://www.orthodb.org/?gene=A0A8V0ZLN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12113:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12113:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04706", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04706", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999995", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999995", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPFPALLCILAALLPAAAAHLWAWMYALPQHPPDRAALGRSAGPGGSAEEVTPCGPTTPCAHGHFCDEHFGLCLPTRPAGQYCRRDTHCAHGLLCTFGKCQQPVPDGQEGARCQRDEDCGAGGCCARRHGELLCQQRLELGQSCHVPPGGLAFSINQVCPCQAGLVCRASPPPREKAFEYWPEKSEWRCRQP", "length": 193, "header": "tr|A0A8V0ZLN8-1|A0A8V0ZLN8_CHICK Isoform 1 of Dickkopf N-terminal cysteine-rich domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100858629 PE=3 SV=1 CANONICAL=A0A8V0ZLN8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8/entry#A0A8V0ZLN8-1", "sequence": { "sequence": "MQPFPALLCILAALLPAAAAHLWAWMYALPQHPPDRAALGRSAGPGGSAEEVTPCGPTTPCAHGHFCDEHFGLCLPTRPAGQYCRRDTHCAHGLLCTFGKCQQPVPDGQEGARCQRDEDCGAGGCCARRHGELLCQQRLELGQSCHVPPGGLAFSINQVCPCQAGLVCRASPPPREKAFEYWPEKSEWRCRQP", "length": 193, "header": "tr|A0A8V0ZLN8-1|A0A8V0ZLN8_CHICK Isoform 1 of Dickkopf N-terminal cysteine-rich domain-containing protein OS=Gallus gallus OX=9031 GN=LOC100858629 PE=3 SV=1 CANONICAL=A0A8V0ZLN8-1" }, "locus": { "chromosome": "27", "start_pos": 4092058, "end_pos": 4090318, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052819.1", "url": "https://www.ensembl.org/id/ENSGALT00010052819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031725.1", "url": "https://www.ensembl.org/id/ENSGALP00010031725.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { 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"https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "receptor antagonist activity", "id": "GO:0048019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048019", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8" } ], "pmid": "" }, { "name": "co-receptor binding", "id": "GO:0039706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLN8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN8" }, { "id": "PF04706", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04706" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dickkopf N-terminal cysteine-rich", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 102, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 58 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"MTAPSSVNSRTFNASHTGMLGHACKHKKPLSAAKACITEILPSKFKPKLAAPAALGQDKKGILLSHEKAQSCENLRSSIALFDNKKSFMVDVGESIENMLMKSKQEYAIKSGSTMSLQEYGTNSRRGYLFPASRKSGMEFTMLYKDMHQINRSRIQLGTVSSCSVRDIASQFENEAKDRMEHSLSREDSEQIPKDTVSSRISAFEQLIQRSRSMPALDFSTGQSKFTTSLQSKACLGSAYSAEILLDLPKIHQEEKDAASLADKSSHSCSNVEDTASDVSDAIPMDTLSACTDEIDLLSNASNDSGGSSSNINGPQKHKVNRCKGTCPASYTRFTTIRRHEQQQASRNTDSKGIYGDRNTLPRNVYLMSPLPFRVKKPFQHKSSRTPPPDCPGALAVPSPENTDDPIQLQGSVGDKSHHSRHEPCSRSRPLAPRRLSSFDVVERLSYFPSMGSSRDSSMGRSDTPDSLHNGNPIPYALYHSLDTNNNPQSELGTYLGGGFLCSLPVSLHLYCSPFPFPFLPQPLHFYSPPLHLLTLPIFFFWYVLRPLRVLLSIFVQDMLTAALLRNDYHCLSNHTGFSWSLKPLLGYKNLNMRYF", "length": 596, "header": "tr|A0A8V0ZLQ6-1|A0A8V0ZLQ6_CHICK Isoform 1 of Sorbin and SH3 domain-containing protein 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZLQ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ6/entry#A0A8V0ZLQ6-1", "sequence": { "sequence": 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"site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 600, "start_aa": "Thr", "end_pos": 600, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr600", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 609, "start_aa": "Thr", "end_pos": 609, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr609", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": 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"MHTNAFGSREEKARTHLSRGTNKCKKILLLCMAICTAAGVAKAPRQAIDVLHRLGLVSYVQQPSVTPVPSAVPPLPRGVRLAVSGVVLTGDAHVEASVAQVIPASLGHHFIILVGLYSYTVNNAFLFSIRNKARLQFGIQLLPRKVAVYTGGKQPAYFDYSVHNEQWHWFAIEIRDKTVSMFAECGQKYYRREMLYEVEAFDLDGLFTLGRMNSHSVSFEGVICQLDIIPSAEASANYCKYVKQQCRQAETYRSPLGTPYASGVLDVFLKKKFGEKKQWEDVSYKRKEASNGPVTNVAQIHSVLEYLESINVSASEFAESKPLLLEVWPETELQEEVSLPFHQQEPSKERGSTERNKASYPNTSHTITEDADRQSELSLIFPVKQNKMKSKGADKEKQHLDEPTKKQQIFNTTLYSLTADLSLDNQLGLKEEGPFDANKTYRTENTYIDVDNYNYEDQGKMFEIGSSRGLKGETGPPGPPGPPGLPGPSGKRGPRGMPGPHGNPGLPGLPGPKGPKGDPGFSPGKAKRGEKGDPGPIGFSGPPGIKGQKGHKGFMGLQGPRGEQGVPGMAGNVGAVGYPGRQGLAGPEGNPGPKGARGFIGPPGVAGQRGSEGERGIPGFHGKRGPKGRQGFPGDFGDRGPPGPDGNPGIVGGVGPPGFPGLRGDVGPEGLRGPSGIPGPMGLPGNMGQPGMKGDKGEHGLAGDPGDQGYPGDKGAPGSPGPPGIRGKPGPQGKIGDPGSQGPLGPPGPEGFPGDIGVPGLNGPEGPKGLLGDRGSPGPQGPKGVEGEVGPAGPIGAVGPRGKPGQKGYVGEPGPEGLKGEQGDQGNIGKTGEAGSAGLPGETGSSGSLGEKGERGSPGPVGPPGEKGVMGYIGPPGGPGPVGPEGIPGPSGTRGPPGPQGPKGRRGPRGIDGPLGETGTQGVKGERGDPGKKGTPGLIGKAGNPGQRGDQGALGLPGPPGTTGDRGPMGETGPRGQPGDAGAIGDMGFEGPPGPEGEPGLQGEPGTKGDAGPAGKAGEPGDQGLRGEPGPPGEDGVQGRDGPKGEPGEQGLHGETGEKGEMGTPGSAGPPGEPGIMGAPGPEGTPGNPGQRGRLGKKGEKGQLGPPGEIGPAGGSGQHGKIGPKGARGTRGPLGHPGGMGPGGELGIPGYGGHQGPAGPSGPPGPKGEKGYPGEDSTVLGPPGPIGEPGPTGERGDRGEPGDEGYKGHIGLPGLRGQIGQQGPPGEPGELGEQGVKGERGSKGPTGKKGATGQAGKPGVPGKPGPAGQKGAVGYPGPEGIPGNPGKPGLWGKPGPKGNKGSPGLAGLAGYPGARGPKGLPGMPGPMGAPGLKGAEGLQGHPGKRGKRGHPGSQGDQGPAGEVGAKGQTGEDGDQGLMGFQGFPGPKGPAGDVGLVGILGPKGPTGQIGYSGPVGQEGITGPTGRPGPRGEKGTRGEMGPQGPRGQTGAPGSPGPPGPRKIVDINAAVQALIASNAALQMERYQNTEVTLLDHSTEIYKTLHYLSNLLHSIKNPLGTRDNPARICRDLLSCERKVSDGKYWIDPNIGCPSDAIEVFCNFTAGGQTCLTPPSVTKLEFGIGKVQMNFLHLLSSEATHSITVHCLNTPMWGLSEAGGQKTSVSFRGWNGQVFKANSLLEPKVLVDECMIQDGSWHKTQFFFHTQDTNQLPVVQVHTLPHLKPGQQHFIESGLVCFL", "length": 1694, "header": "tr|A0A8V0ZLQ9-1|A0A8V0ZLQ9_CHICK Isoform 1 of Collagen alpha-1(XXIV) chain OS=Gallus gallus OX=9031 GN=COL24A1 PE=4 SV=1 CANONICAL=A0A8V0ZLQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15884917, "end_pos": 15769748, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056565.1", "url": "https://www.ensembl.org/id/ENSGALT00010056565.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034307.1", "url": "https://www.ensembl.org/id/ENSGALP00010034307.1" } ] } }, { "isoform_ac": "A0A8V0ZTW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ9/entry#A0A8V0ZTW9-1", "sequence": { "sequence": "MHLGAERRRRGRISPAAPTKILLLCMAICTAAGVAKAPRQAIDVLHRLGLVSYVQQPSVTPVPSAVPPLPRGVRLAVSGVVLTGDAHVEASVAQVIPASLGHHFIILVGLYSYTVNNAFLFSIRNKARLQFGIQLLPRKVAVYTGGKQPAYFDYSVHNEQWHWFAIEIRDKTVSMFAECGQKYYRREMLYEVEAFDLDGLFTLGRMNSHSVSFEGVICQLDIIPSAEASANYCKYVKQQCRQAETYRSPLGTPYASGVLDVFLKKKFGEKKQWEDVSYKRKEASNGPVTNVAQIHSVLEYLESINVSASEFAESKPLLLEVWPETELQEEVSLPFHQQEPSKERGSTERNKASYPNTSHTITEDADRQSELSLIFPVKQNKMKSKGADKEKQHLDEPTKKQQIFNTTLYSLTADLSLDNQLGLKEEGPFDANKTYRTENTYIDVDNYNYEDQGKMFEIGSSRGLKGETGPPGPPGPPGLPGPSGKRGPRGMPGPHGNPGLPGLPGPKGPKGDPGFSPGKAKRGEKGDPGPIGFSGPPGIKGQKGHKGFMGLQGPRGEQGVPGMAGNVGAVGYPGRQGLAGPEGNPGPKGARGFIGPPGVAGQRGSEGERGIPGFHGKRGPKGRQGFPGDFGDRGPPGPDGNPGIVGGVGPPGFPGLRGDVGPEGLRGPSGIPGPMGLPGNMGQPGMKGDKGEHGLAGDPGDQGYPGDKGAPGSPGPPGIRGKPGPQGKIGDPGSQGPLGPPGPEGFPGDIGVPGLNGPEGPKGLLGDRGSPGPQGPKGVEGEVGPAGPIGAVGPRGKPGQKGYVGEPGPEGLKGEQGDQGNIGKTGEAGSAGLPGETGSSGSLGEKGERGSPGPVGPPGEKGVMGYIGPPGGPGPVGPEGIPGPSGTRGPPGPQGPKGRRGPRGIDGPLGETGTQGVKGERGDPGKKGTPGLIGKAGNPGQRGDQGALGLPGPPGTTGDRGPMGETGPRGQPGDAGAIGDMGFEGPPGPEGEPGLQGEPGTKGDAGPAGKAGEPGDQGLRGEPGPPGEDGVQGRDGPKGEPGEQGLHGETGEKGEMGTPGSAGPPGEPGIMGAPGPEGTPGNPGQRGRLGKKGEKGQLGPPGEIGPAGGSGQHGKIGPKGARGTRGPLGHPGGMGPGGELGIPGYGGHQGPAGPSGPPGPKGEKGYPGEDSTVLGPPGPIGEPGPTGERGDRGEPGDEGYKGHIGLPGLRGQIGQQGPPGEPGELGEQGVKGERGSKGPTGKKGATGQAGKPGVPGKPGPAGQKGAVGYPGPEGIPGNPGKPGLWGKPGPKGNKGSPGLAGLAGYPGARGPKGLPGMPGPMGAPGLKGAEGLQGHPGKRGKRGHPGSQGDQGPAGEVGAKGQTGEDGDQGLMGFQGFPGPKGPAGDVGLVGILGPKGPTGQIGYSGPVGQEGITGPTGRPGPRGEKGTRGEMGPQGPRGQTGAPGSPGPPGPRKIVDINAAVQALIASNAALQMERYQNTEVTLLDHSTEIYKTLHYLSNLLHSIKNPLGTRDNPARICRDLLSCERKVSDGKYWIDPNIGCPSDAIEVFCNFTAGGQTCLTPPSVTKLEFGIGKVQMNFLHLLSSEATHSITVHCLNTPMWGLSEAGGQKTSVSFRGWNGQVFKANSLLEPKVLVDECMIQDGSWHKTQFFFHTQDTNQLPVVQVHTLPHLKPGQQHFIESGLVCFL", "length": 1688, "header": "tr|A0A8V0ZTW9-1|A0A8V0ZLQ9_CHICK Computationally mapped isoform of Collagen alpha-1(XXIV) chain OS=Gallus gallus OX=9031 GN=COL24A1 PE=4 SV=1 CANONICAL=A0A8V0ZLQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15884917, "end_pos": 15769758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056538.1", "url": "https://www.ensembl.org/id/ENSGALT00010056538.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034280.1", "url": "https://www.ensembl.org/id/ENSGALP00010034280.1" } ] } }, { "isoform_ac": "A0A8V0ZTZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ9/entry#A0A8V0ZTZ0-1", "sequence": { "sequence": "MHLGAERRRRGRISPAAPTKILLLCMAICTAAGVAKAPRQAIDVLHRLGLVSYVQQPSVTPVPSAVPPLPRGVRLAVSGVVLTGDAHVEASVAQVIPASLGHHFIILVGLYSYTVNNAFLFSIRNKARLQFGIQLLPRKVAVYTGGKQPAYFDYSVHNEQWHWFAIEIRDKTVSMFAECGQKYYRREMLYEVEAFDLDGLFTLGRMNSHSVSFEGVICQLDIIPSAEASANYCKYVKQQCRQAETYRSPLGTPYASGVLDVFLKKKFGEKKQWEDVSYKRKEASNGPVTNVAQIHSVLEYLESINVSASEFAESKPLLLEVWPETELQEEVSLPFHQQEPSKERGSTERNKASYPNTSHTITEDADRQSELSLIFPVKQNKMKSKGADKEKQHLDEPTKKQQIFNTTLYSLTADLSLDNQLGLKEEGPFDANKTYRTENTYIDVDNYNYEDQGKMFEIGSSRGLKGETGPPGPPGPPGLPGPSGKRGPRGMPGPHGNPGLPGLPGPKGPKGDPGFSPGKAKRGEKGDPGPIGFSGPPGIKGQKGHKGFMGLQGPRGEQGVPGMAGNVGAVGYPGRQGLAGPEGNPGPKGARGFIGPPGVAGQRGSEGERGIPGFHGKRGPKGRQGFPGDFGDRGPPGPDGNPGIVGGVGPPGFPGLRGDVGPEGLRGPSGIPGPMGLPGNMGQPGMKGDKGEHGLAGDPGDQGYPGDKGAPGSPGPPGIRGKPGPQGKIGDPGSQGPLGPPGPEGFPGDIGVPGLNGPEGPKGLLGDRGSPGPQGPKGVEGEVGPAGPIGAVGPRGKPGQKGYVGEPGPEGLKGEQGDQGNIGKTGEAGSAGLPGETGSSGSLGEKGERGSPGPVGPPGEKGVMGYIGPPGGPGPVGPEGIPGPSGTRGPPGPQGPKGRRGPRGIDGPLGETGTQGVKGERGDPGKKGTPGLIGKAGNPGQRGDQGALGLPGPPGTTGDRGPMGETGPRGQPGDAGAIGDMGFEGPPGPEGEPGLQGEPGTKGDAGPAGKAGEPGDQGLRGEPGPPGEDGVQGRDGPKGEPGEQGLHGETGEKGEMGTPGSAGPPGEPGIMGAPGPEGTPGNPGQRGRLGKKGEKGQLGPPGEIGPAGGSGQHGKIGPKGARGTRGPLGHPGGMGPGGELGIPGYGGHQGPAGPSGPPGPKGEKGYPGEDSTVLGPPGPIGEPGPTGERGDRGEPGDEGYKGHIGLPGLRGQIGQQGPPGEPGELGEQGVKGERGSKGPTGKKGATGQAGKPGVPGKPGPAGQKGAVGYPGPEGIPGNPGKPGLWGKPGPKGAEGLQGHPGKRGKRGHPGSQGDQGPAGEVGAKGQTGEDGDQGLMGFQGFPGPKGPAGDVGLVGILGPKGPTGQIGYSGPVGQEGITGPTGRPGPRGEKGTRGEMGPQGPRGQTGAPGSPGPPGPRKIVDINAAVQALIASNAALQMERYQNTEVTLLDHSTEIYKTLHYLSNLLHSIKNPLGTRDNPARICRDLLSCERKVSDGKYWIDPNIGCPSDAIEVFCNFTAGGQTCLTPPSVTKLEFGIGKVQMNFLHLLSSEATHSITVHCLNTPMWGLSEAGGQKTSVSFRGWNGQVFKANSLLEPKVLVDECMIQDGSWHKTQFFFHTQDTNQLPVVQVHTLPHLKPGQQHFIESGLVCFL", "length": 1652, "header": "tr|A0A8V0ZTZ0-1|A0A8V0ZLQ9_CHICK Computationally mapped isoform of Collagen alpha-1(XXIV) chain OS=Gallus gallus OX=9031 GN=COL24A1 PE=4 SV=1 CANONICAL=A0A8V0ZLQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15884917, "end_pos": 15769758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056559.1", "url": "https://www.ensembl.org/id/ENSGALT00010056559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034301.1", "url": "https://www.ensembl.org/id/ENSGALP00010034301.1" } ] } }, { "isoform_ac": "A0A8V0ZUX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ9/entry#A0A8V0ZUX7-1", "sequence": { "sequence": "MAICTAAGVAKAPRQAIDVLHRLGLVSYVQQPSVTPVPSAVPPLPRGVRLAVSGVVLTGDAHVEASVAQVIPASLGHHFIILVGLYSYTVNNAFLFSIRNKARLQFGIQLLPRKVAVYTGGKQPAYFDYSVHNEQWHWFAIEIRDKTVSMFAECGQKYYRREMLYEVEAFDLDGLFTLGRMNSHSVSFEGVICQLDIIPSAEASANYCKYVKQQCRQAETYRSPLGTPYASGVLDVFLKKKFGEKKQWEDVSYKRKEASNGPVTNVAQIHSVLEYLESINVSASEFAESKPLLLEVWPETELQEEVSLPFHQQEPSKERGSTERNKASYPNTSHTITEDADRQSELSLIFPVKQNKMKSKGADKEKQHLDEPTKKQQIFNTTLYSLTADLSLDNQLGLKEEGPFDANKTYRTENTYIDVDNYNYEDQGKMFEIGSSRGLKGETGPPGPPGPPGLPGPSGKRGPRGMPGPHGNPGLPGLPGPKGPKGDPGFSPGKAKRGEKGDPGPIGFSGPPGIKGQKGHKGFMGLQGPRGEQGVPGMAGNVGAVGYPGRQGLAGPEGNPGPKGARGFIGPPGVAGQRGSEGERGIPGFHGKRGPKGRQGFPGDFGDRGPPGPDGNPGIVGGVGPPGFPGLRGDVGPEGLRGPSGIPGPMGLPGNMGQPGMKGDKGEHGLAGDPGDQGYPGDKGAPGSPGPPGIRGKPGPQGKIGDPGSQGPLGPPGPEGFPGDIGVPGLNGPEGPKGLLGDRGSPGPQGPKGVEGEVGPAGPIGAVGPRGKPGQKGYVGEPGPEGLKGEQGDQGNIGKTGEAFSLLNSISYPSVKLLPGKYEDQLAYLEKLGHLEALVKRESEAVQDQ", "length": 849, "header": "tr|A0A8V0ZUX7-1|A0A8V0ZLQ9_CHICK Computationally mapped isoform of Collagen alpha-1(XXIV) chain OS=Gallus gallus OX=9031 GN=COL24A1 PE=4 SV=1 CANONICAL=A0A8V0ZLQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15838852, "end_pos": 15774903, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056527.1", "url": "https://www.ensembl.org/id/ENSGALT00010056527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034269.1", "url": "https://www.ensembl.org/id/ENSGALP00010034269.1" } ] } }, { "isoform_ac": "A0A8V0ZZF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ9/entry#A0A8V0ZZF9-1", "sequence": { "sequence": "MHLGAERRRRGRISPAAPTKILLLCMAICTAAGVAKAPRQAIDVLHRLGLVSYVQQPSVTPVPSAVPPLPRGVRLAVSGVVLTGDAHVEASVAQVIPASLGHHFIILVGLYSYTVNNAFLFSIRNKARLQFGIQLLPRKVAVYTGGKQPAYFDYSVHNEQWHWFAIEIRDKTVSMFAECGQKYYRREMLYEVEAFDLDGLFTLGRMNSHSVSFEGVICQLDIIPSAEASANYCKYVKQQCRQAETYRSPLGTPYASGVLDVFLKKKFGEKKQWEDVSYKRKEASNGPVTNVAQIHSVLEYLESINVSASEFAESKPLLLEVWPETELQEEVSLPFHQQEPSKERGSTERNKASYPNTSHTITEDADRQSELSLIFPVKQNKMKSKGADKEKQHLDEPTKKQQIFNTTLYSLTADLSLDNQLGLKEEGPFDANKTYRTENTYIDVDNYNYEDQGKMFEIGSSRGLKGETGPPGPPGPPGLPGPSGKRGPRGMPGPHGNPGLPGLPGPKGPKGDPGFSPGKAKRGEKGDPGPIGFSGPPGIKGQKGHKGFMGLQGPRGEQGVPGMAGNVGAVGYPGRQGLAGPEGNPGPKGARGFIGPPGVAGQRGSEGERGIPGFHGKRGPKGRQGFPGDFGDRGPPGPDGNPGIVGGVGPPGFPGLRGDVGPEGLRGPSGIPGPMGEHGLAGDPGDQGYPGDKGAPGSPGPPGIRGKPGPQGKIGDPGSQGPLGPPGPEGFPGDIGVPGLNGPEGPKGLLGDRGSPGPQGPKGVEGEVGPAGPIGAVGPRGKPGQKGYVGEPGPEGLKGEQGDQGNIGKTGEAGSAGLPGETGSSGSLGEKGERGSPGPVGPPGEKGVMGYIGPPGGPGPVGPEGIPGPSGTRGPPGPQGPKGRRGPRGIDGPLGETGTQGVKGERGDPGKKGTPGLIGKAGNPGQRGDQGALGLPGPPGTTGDRGPMGETGPRGQPGDAGAIGDMGFEGPPGPEGEPGLQGEPGTKGDAGPAGKAGEPGDQGLRGEPGPPGEDGVQGRDGPKGEPGEQGLHGETGEKGEMGTPGSAGPPGEPGIMGAPGPEGTPGNPGQRGRLGKKGEKGQLGPPGEIGPAGGSGQHGKIGPKGARGTRGPLGHPGGMGPGGELGIPGYGGHQGPAGPSGPPGPKGEKGYPGEDSTVLGPPGPIGEPGPTGERGDRGEPGDEGYKGHIGLPGLRGQIGQQGPPGEPGELGEQGVKGERGSKGPTGKKGATGQAGKPGVPGKPGPAGQKGAVGYPGPEGIPGNPGKPGLWGKPGPKGNKGSPGLAGLAGYPGARGPKGLPGMPGPMGAPGLKGAEGLQGHPGKRGKRGHPGSQGDQGPAGEVGAKGQTGEDGDQGLMGFQGFPGPKGPAGDVGLVGILGPKGPTGQIGYSGPVGQEGITGPTGRPGPRGEKGTRGEMGPQGPRGQTGAPGSPGPPGPRKIVDINAAVQALIASNAALQMERYQNTEVTLLDHSTEIYKTLHYLSNLLHSIKNPLGTRDNPARICRDLLSCERKVSDGKYWIDPNIGCPSDAIEVFCNFTAGGQTCLTPPSVTKLEFGIGKVQMNFLHLLSSEATHSITVHCLNTPMWGLSEAGGQKTSVSFRGWNGQVFKANSLLEPKVLVDECMIQDGSWHKTQFFFHTQDTNQLPVVQVHTLPHLKPGQQHFIESGLVCFL", "length": 1673, "header": "tr|A0A8V0ZZF9-1|A0A8V0ZLQ9_CHICK Computationally mapped isoform of Collagen alpha-1(XXIV) chain OS=Gallus gallus OX=9031 GN=COL24A1 PE=4 SV=1 CANONICAL=A0A8V0ZLQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15884917, "end_pos": 15769758, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056551.1", "url": "https://www.ensembl.org/id/ENSGALT00010056551.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034293.1", "url": "https://www.ensembl.org/id/ENSGALP00010034293.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1085, "start_aa": "Thr", "end_pos": 1085, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1085", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1192, "start_aa": "Thr", "end_pos": 1192, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1192", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424526", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424526", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LLD1-1", "protein_name": "Collagen type XXIV alpha 1 chain", "gene_name": "Col24a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHLGAYRTRHGKVSPTTETKLLLRFTVLCVAWITVRAQGQGIDILQQLGLGGRDVRYASSVTAVPSLSTPLPQGVHLTEFGVVLTDNAYIESPLVNILPVSLRQPLTVLIGLQSLQVNNAFLFSIRNNNRLQFGVQLLPKKLIVHVGGKRTVTFDYSIHDERWHSLAITVDHRVVSMFVECGKRYFSGETTSEVQTFDPHSVFTLGSMNNSSAHFEGTVCQLDIVPSAVASADYCSHLKQQCPRTDASQAERSLSHTEVVPTRYPEHTPLPRGLAGTELTQKRFTEQAPFPKGFDEAELPRETFTDDSKSISNNTGNGSATVHESHEHQTPRVRLTSFHSENISAVTLPSYRIQAKEITTKGETNLTLSVPHRLPSEAGMNEEERISPLFPEFNITQHEEAAGLPSPKKASSSIAQTNQDTVTNLKKAITANLHTNELMEMERILNSTLYKVIHGPSVDNHLELRKEGEFYPDATNPMENSYEPQPYEYYYYEDYNAMLDLEYLRGPKGDTGPPGPPGPMGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGLSPGQAASGEKGDPGLLGLVGPPGLQGEKGLKGHTGLPGLRGEQGIPGLAGNVGSPGYPGRQGLAGPEGNPGSKGVRGFIGSPGEAGQLGPEGERGTPGVRGKKGPKGRQGFPGDFGDRGPAGLDGSPGLVGGIGPPGFPGIRGNVGPAGPVGPPGVPGPMGLSGSRGPPGIKGDKGEQGVAGEPGEPGYPGDKGAIGSPGPPGIRGKSGPSGQPGDPGPQGPTGPPGPEGFPGDIGIPGQNGPEGPKGHLGSRGPPGPPGLKGTQGEEGPIGPFGELGSRGKPGRKGYMGEPGPEGLKGETGDQGDIGKIGETGPVGLPGEVGITGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGAPGPMGPIGLPGLVGARGAPGSPGPKGQRGPRGPDGLAGDQGGHGAKGEKGNQGKRGLPGRAGKTGSPGERGVQGKPGLQGLPGSSGDMGPAGEPGPRGLPGDAGLPGEMGVEGPPGTEGDSGLQGEPGAKGDVGPTGSEGATGEPGPRGEPGAPGEEGLQGKDGLKGAPGGSGLPGEDGEKGEMGLPGTAGPVGRPGQMGPPGSEGIVGTPGERGRTGKKGDKGQTGPVGEAGSRGSPGRVGDSGPKGARGTRGAVGPLGLMGPEGEPGIPGYRGLEGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPMGERGERGEHGEEGYKGHMGVPGLRGAAGQQGPPGEPGDQGEQGLKGERGSEGPQGKKGVPGPSGKPGIPGLPGLPGPKGLQGYHGVDGLSGYPGKPGLLGKQGLPGTTGSPGRTGLAGSPGPQGGKGSSGPPGSPGVPGPKGEQGLPGQPGIPGQRGQRGTQGDQGRRGEPGLKGQPGEHGNQGLTGFQGFPGPRGPEGDAGIIGIVGPKGPVGQRGNTGPLGREGIIGPTGGTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRRQMDINAAIGALIESNSAQQMESYQNTEVTFLSQGTEISKTLAYLSSLLSSIKNPLGTRENPARICKDLLSCQYEVSDGKYWIDPNLGCSSDAFEVFCNFSAGGQTCVSPVSVTKLEFGVGKVQMNFLHLLSSEATHIITLHCLNTPRRTGTPADGPELPISFKGWNGQIFEENTLLEPQVLSDDCKIQDGSWHKAKFLFHTQNPNQLPVTEVQNLPHLRTEQKHYIESSSVCFL", "length": 1731 }, "evidence": [ { "id": "A0A8V0ZLQ9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLQ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q17RW2-1", "protein_name": "Collagen alpha-1(XXIV) chain", "gene_name": "COL24A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHLRAHRTRRGKVSPTAKTKSLLHFIVLCVAGVVVHAQEQGIDILHQLGLGGKDVRHSSPATAVPSASTPLPQGVHLTESGVIFKNDAYIETPFVKILPVNLGQPFTILTGLQSHRVNNAFLFSIRNKNRLQLGVQLLPKKLVVHIRGKQPAVFNYSVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEVQTFDSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQCRQADKYQPETSIPCTTLIPTKIPEHSPPPKLFAEKVLSEDTFTEGKSIPNIIKNDSETVYKRQEHQISRSQLSSLQSGNVSAVDLTNHGIQAKEMITEEDTQTNFSLSVTTHRISEAKMNTKEKFSSLLNMSDNITQHDDRVTGLSLFKKMPSILPQIKQDTITNLKKAITANLHTNELMEMQPILNTSLHRVTNEPSVDNHLDLRKEGEFYPDATYPIENSYETELYDYYYYEDLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQMESYQNTEVTLIDHSEEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDAIEVFCNFSAGGQTCLPPVSVTKLEFGVGKVQMNFLHLLSSEATHIITIHCLNTPRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFHTQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL", "length": 1714 }, "evidence": [ { "id": "A0A8V0ZLQ9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLQ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q30D77-1", "protein_name": "Collagen alpha-1(XXIV) chain", "gene_name": "Col24a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHLGAYRTRHGKVSPTTETKLFLRFIVLCVVWISVHAQGQGIDILQQLGLGGRDVRYTSSVTAVPSSSWSTPLPQGVHLTDFGVILTDNAYIESPLVNILPISLRQPLTVLIGLQSFKVNNAFLFSIRNNNRLQFGVQLLPKKLIVHVGGKQTVTFNYSAHDERWHSFAITVDHHVISMFVECGKRHFSGETTSDVQTFDPHSVFTLGSINNSSAHFEGTVCQLEIMPSTAASAEYCRHLKQQCLRADASQAQRNLPHTAGMPTRHPAHTPLPRGFPGTDSPQKRFTEQDSLPKGFDGTELPRETFADGKSIPNNRSNGSATVHESQEHQTPRAQLTSFHSGNISAVTLPNYRIQAKEITTKEETNLTLSVAHHLPSEARMNEEGRINPLFAGFDNITQHEEAAGLPLPKKASSGFAHTNQDTMKNLEKALTANLYTNELIEMERILNSTLYRVMYGPSVDNHLELRKEGEFYPDATNPIEGSYEPQAYDYYSYEDYNAVLDMEYLRGPKGDPGPPGPPGPMGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGLSPGQAASGEKGDPGLLGLVGPPGLQGAKGLKGHPGLPGLRGEHGLPGLAGNIGSPGYPGRQGLAGPEGNPGSKGVRGFIGSPGEVGQLGPEGERGTPGVRGKKGPKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGVTGSVGPAGPTGPPGAPGPMGLSGSRGPSGIKGDKGEQGVAGEPGEPGYPGDKGNIGSPGPPGIRGKSGPSGQPGDPGPQGPSGPPGPEGFPGDIGIPGQNGPEGPKGHLGNRGPPGPPGLKGTQGEEGPIGPFGELGSRGKPGRKGYMGEPGPEGLKGEVGDQGDIGKTGETGPVGLPGEVGITGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGAPGPMGPLGLPGLVGARGAPGSPGPKGQRGPRGPDGLAGDQGGHGAKGEKGNQGKRGLPGLPGKAGSPGERGVQGKPGFQGLPGSSGDVGPAGEPGPRGLPGIAGLPGEMGVEGPPGTEGDSGLQGEPGAKGDGGPAGSAGATGEPGPRGEPGAPGEEGLQGKDGLKGAPGGSGLPGEDGDKGEMGLPGTAGPVGRPGQMGLPGPEGIVGTPGQRGRLGKKGDKGQVGPTGEAGSRGPPGSVGENGPKGARGTRGAVGPLGLMGPEGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPPGEPGPMGEQGETGEHGEEGYKGHMGVPGLRGATGQQGPPGEPGDQGGQGPKGERGSEGPQGKRGVPGPSGKPGIPGVPGFPGPKGLQGYPGVDGMSGYPGKPGLPGKQGLLGVPGSPGRTGVAGSPGPQGGKGASGPPGSPGAPGPKGEQGLPGQPGVPGQRGHRGTPGDQGLRGAPGLKGQPGEHGDQGLAGFQGFPGPRGPEGDAGIVGIVGPKGPIGQRGNTGPLGREGIIGPTGGTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRRQMDINAAIRALIESNSAQQMESYQNTEGTLISHSSDIFKTLTYLSSLLSSIKNPLGTRENPARICKDLLSCQYKVSDGKYWIDPNLGCSSDAFEVFCNFSAGGQTCLSPVSVTKLEFGVSKVQMNFLHLLSSEATHTITIHCLNTPRWSSTWADGPELPISFKGWNGQIFEENTLLEPQVLSDDCKIQDGSWHKAKFLFHTQNPNQLPVTEVQNLPHLGTEQKRYIESNSVCFL", "length": 1733 }, "evidence": [ { "id": "A0A8V0ZLQ9", "url": "https://omabrowser.org/oma/group/A0A8V0ZLQ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ9" } ], "pmid": "" }, { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1558, "end_pos": 1560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZLQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ9" }, { "id": "PS51461", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51461" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrillar collagen NC1", "eco_id": "ECO_0000259", "start_pos": 1495, "end_pos": 1694, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1085, 1192 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1558, "end_pos": 1560 }, { "start_pos": 311, "end_pos": 313 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 438, "end_pos": 440 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLU8-1", "uniprot_ac": "A0A8V0ZLU8", "uniprot_id": "A0A8V0ZLU8_CHICK", "mass": { "chemical_mass": 55839.0, "monoisotopic_mass": 55839.0 }, "refseq": { "ac": "XP_003641438", "name": "cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641438" }, "gene_names": [ { "name": "CREB3L1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU8" } ] }, { "name": "CREB3L1", "type": "synonym", "evidence": [ { "id": "XP_003641438", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641438" } ] } ], "protein_names": [ { "name": "cAMP responsive element binding protein 3 like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU8/entry#names_and_taxonomy" } ] }, { "name": "cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003641438", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641438" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003641438.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003641438", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641438" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CREB3L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU8", "locus": { "chromosome": "5", "start_pos": 23227767, "end_pos": 23271032, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023217", "url": "https://www.ensembl.org/id/ENSGALG00010023217" } ] } } ], "crossref": [ { "id": "A0A8V0ZLU8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLU8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14689", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14689", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859610", "url": "https://www.ncbi.nlm.nih.gov/gene/100859610", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100859610", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859610", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZLU8", "url": "https://www.orthodb.org/?gene=A0A8V0ZLU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZK9", "url": "https://www.orthodb.org/?gene=A0A8V0ZZK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46004", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46004", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46004:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46004:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003641438", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003641438", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSILEPFAAERLFPPAGPGFLDLGDFSEADFLSNVHFSENLDHFSDNMDDFSNDLFSSFFDDPVLAEKNPLLDMDLDPPTPGIQAEHSYSLSGDSAPQSPLMPVKTEDNANELENGVWSLGPKLCSIMVKQEQNLALDPPESQLAASSRPVLNLNPLQRLPVPEETPIEMTPAPVIKAEPKEVNQFLNVPADDLVQMPPTPPSSHGSDSDGSQSPRSLPPSSPARPAARSSTAISSSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYPIPTKLPLTKAEEKALKRVRRKIKNKISAQESRRKKKEYVECLEKKVETYTTENNELWKKVETLESANRTLLQQLQKLQALVAGKVSRPYKMASTQTGTCLMVLVLCFVLILGSLMPCLPEFSTASQTVKATPAPDIYTTSKIQSRSLLFYDEGAGSLEESYSSFLTMDHPEGWEAEKGQSDEPRPHLARTHETAKYMSKSHLENPDQNQTDPTLTHLKEQFHERETSSSETAEYL", "length": 505, "header": "tr|A0A8V0ZLU8-1|A0A8V0ZLU8_CHICK Isoform 1 of cAMP responsive element binding protein 3 like 1 OS=Gallus gallus OX=9031 GN=CREB3L1 PE=3 SV=1 CANONICAL=A0A8V0ZLU8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLU8-1", "url": 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CANONICAL=A0A8V0ZLU8-1" }, "locus": { "chromosome": "5", "start_pos": 23264951, "end_pos": 23230366, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056601.1", "url": "https://www.ensembl.org/id/ENSGALT00010056601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034343.1", "url": "https://www.ensembl.org/id/ENSGALP00010034343.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 201, "start_aa": "Thr", "end_pos": 201, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr201", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", 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"evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022137", "url": "https://www.ensembl.org/id/ENSGALG00010022137" } ] } } ], "crossref": [ { "id": "A0A8V0ZLV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03141", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03141", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR029062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLV0", "url": "https://www.orthodb.org/?gene=A0A8V0ZLV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP05", "url": "https://www.orthodb.org/?gene=A0A8V0ZP05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48094", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48094", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48094:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48094:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP05", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGCMRRRLRAPPPVPAMSERLGKPTCLLVASAAAAGVSAQSFLQCFTLSSSAFNLQVATPGGKSIDFVDVNESNMRWIQDFRMKSYANPAKLESIDGARYHALLIPNCPGAMTDLANSGYLAKILQHFCTENKPVCAVGHGVAALCCATNEDKTWVFQGYSLTGPSVYELIRQPNFASLPIIVEDFVKDSGATFSASKPDAVHVVLDRHLVTGQNENSTLPAVQNLLILCNVR", "length": 234, "header": "tr|A0A8V0ZLV0-1|A0A8V0ZLV0_CHICK Isoform 1 of Glutamine amidotransferase-like class 1 domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PDDC1 PE=1 SV=1 CANONICAL=A0A8V0ZLV0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV0/entry#A0A8V0ZLV0-1", "sequence": { "sequence": "MRGCMRRRLRAPPPVPAMSERLGKPTCLLVASAAAAGVSAQSFLQCFTLSSSAFNLQVATPGGKSIDFVDVNESNMRWIQDFRMKSYANPAKLESIDGARYHALLIPNCPGAMTDLANSGYLAKILQHFCTENKPVCAVGHGVAALCCATNEDKTWVFQGYSLTGPSVYELIRQPNFASLPIIVEDFVKDSGATFSASKPDAVHVVLDRHLVTGQNENSTLPAVQNLLILCNVR", "length": 234, "header": "tr|A0A8V0ZLV0-1|A0A8V0ZLV0_CHICK Isoform 1 of Glutamine amidotransferase-like class 1 domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PDDC1 PE=1 SV=1 CANONICAL=A0A8V0ZLV0-1" }, "locus": { "chromosome": "5", "start_pos": 659787, "end_pos": 650734, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053858.1", "url": "https://www.ensembl.org/id/ENSGALT00010053858.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032424.1", "url": "https://www.ensembl.org/id/ENSGALP00010032424.1" } ] } }, { "isoform_ac": "A0A8V0ZP05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV0/entry#A0A8V0ZP05-1", "sequence": { "sequence": "MSERLGKPTCLLVASAAAAGVSAQSFLQCFTLSSSAFNLQVATPGGKSIDFVDVNESNMRWIQDFRMKSYANPAKLESIDGARYHALLIPNCPGAMTDLANSGYLAKILQHFCTENMFSWKSWQPMAWTEPVCAVGHGVAALCCATNEDKTWVFQGYSLTGPSVYELIRQPNFASLPIIVEDFVKDSGATFSASKPDAVHVVLDRHLVTGQNENSTLPAVQNLLILCNVRK", "length": 231, "header": "tr|A0A8V0ZP05-1|A0A8V0ZP05_CHICK Computationally mapped isoform of Glutamine amidotransferase-like class 1 domain-containing protein 1 OS=Gallus gallus OX=9031 GN=PDDC1 PE=1 SV=1 CANONICAL=A0A8V0ZLV0-1" }, "locus": { "chromosome": "5", "start_pos": 659867, "end_pos": 650785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053853.1", "url": "https://www.ensembl.org/id/ENSGALT00010053853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032420.1", "url": "https://www.ensembl.org/id/ENSGALP00010032420.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione", "id": "GO:0019243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019243", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV0" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glyoxalase III activity", "id": "GO:0019172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019172", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZLV1-1", "uniprot_ac": "A0A8V0ZLV1", "uniprot_id": "A0A8V0ZLV1_CHICK", "mass": { "chemical_mass": 46507.0, "monoisotopic_mass": 46507.0 }, "refseq": { "ac": "XP_025006423", "name": "single Ig IL-1-related receptor isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006423" }, "gene_names": [ { "name": "SIGIRR", "type": "recommended", "evidence": [ { "id": "A0A8V0ZLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV1" } ] }, { "name": "SIGIRR", "type": "synonym", "evidence": [ { "id": "XP_025006423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006423" } ] } ], "protein_names": [ { "name": "Single Ig and TIR domain containing", "type": "synonym", "evidence": [ { "id": "A0A8V0ZLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV1/entry#names_and_taxonomy" } ] }, { "name": "single Ig IL-1-related receptor isoform X3", "type": "synonym", "evidence": [ { "id": "XP_025006423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006423" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025006423.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025006423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006423" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SIGIRR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV1", "locus": { "chromosome": "5", "start_pos": 1741059, "end_pos": 1736214, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020734", "url": "https://www.ensembl.org/id/ENSGALG00010020734" } ] } } ], "crossref": [ { "id": "A0A8V0ZLV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZLV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "422995", "url": "https://www.ncbi.nlm.nih.gov/gene/422995", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLV1", "url": "https://www.orthodb.org/?gene=A0A8V0ZLV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11890:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11890:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01582", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025006423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPEFCSVPPEIVAPAANETLELALGSQVVLNCTVRWAISEHCEPVPTWTKDGQWLGSESRQDSTWLGQNASERLLATVLQVNLTHNADFGVFACWVSNATASFTLRREEVAGHVSAVLAALLVLSLLVLLAGLYIRCRLSVLLWYRNHYGELEMNDGKLYDAYVSHATAPDDRKFVHFIVKPQLENRYGYKLYLDEQNIMPNAEPSADLIMNVSRCRRLIVVLSVAYLEQDWCNSSFREGLWRLLELSKKPIFIVFESQYREITHPAISLLKQHRSAVTLLVWRAGSMTPSSDFWKELCLALPRKVAFRRTMGDPQTQLQEDKDPMLILHSSYLDSRGDPHPDGDLGLRGCAFRSPLPPRISGPGGPTALATGTVEDTQLKDSHRSEIDISDLGSRNYGARTDFYCLVTEDDI", "length": 414, "header": "tr|A0A8V0ZLV1-1|A0A8V0ZLV1_CHICK Isoform 1 of Single Ig and TIR domain containing OS=Gallus gallus OX=9031 GN=SIGIRR PE=1 SV=1 CANONICAL=A0A8V0ZLV1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV1/entry#A0A8V0ZLV1-1", "sequence": { "sequence": "MPPEFCSVPPEIVAPAANETLELALGSQVVLNCTVRWAISEHCEPVPTWTKDGQWLGSESRQDSTWLGQNASERLLATVLQVNLTHNADFGVFACWVSNATASFTLRREEVAGHVSAVLAALLVLSLLVLLAGLYIRCRLSVLLWYRNHYGELEMNDGKLYDAYVSHATAPDDRKFVHFIVKPQLENRYGYKLYLDEQNIMPNAEPSADLIMNVSRCRRLIVVLSVAYLEQDWCNSSFREGLWRLLELSKKPIFIVFESQYREITHPAISLLKQHRSAVTLLVWRAGSMTPSSDFWKELCLALPRKVAFRRTMGDPQTQLQEDKDPMLILHSSYLDSRGDPHPDGDLGLRGCAFRSPLPPRISGPGGPTALATGTVEDTQLKDSHRSEIDISDLGSRNYGARTDFYCLVTEDDI", "length": 414, "header": "tr|A0A8V0ZLV1-1|A0A8V0ZLV1_CHICK Isoform 1 of Single Ig and TIR domain containing OS=Gallus gallus OX=9031 GN=SIGIRR PE=1 SV=1 CANONICAL=A0A8V0ZLV1-1" }, "locus": { "chromosome": "5", "start_pos": 1740660, "end_pos": 1738402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050106.1", "url": "https://www.ensembl.org/id/ENSGALT00010050106.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029607.1", "url": "https://www.ensembl.org/id/ENSGALP00010029607.1" } ] } } ], "glycosylation": [], "phosphorylation": [], 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regulation of chemokine production", "id": "GO:0032682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV1" } ], "pmid": "" }, { "name": "negative regulation of Toll signaling pathway", "id": "GO:0045751", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045751", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV1" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZLV1", "url": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZM89-1", "uniprot_ac": "A0A8V0ZM89", "uniprot_id": "A0A8V0ZM89_CHICK", "mass": { "chemical_mass": 57079.0, "monoisotopic_mass": 57079.0 }, "refseq": { "ac": "XP_422992", "name": "trichoplein keratin filament-binding protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422992" }, "gene_names": [ { "name": "TCHP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM89" } ] }, { "name": "TCHP", "type": "synonym", "evidence": [ { "id": "XP_422992", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422992" } ] } ], "protein_names": [ { "name": "Trichoplein keratin filament-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM89/entry#names_and_taxonomy" } ] }, { "name": "trichoplein keratin filament-binding protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_422992", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422992" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_422992.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422992", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422992" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM89" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TCHP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM89", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZM89", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZM89", "database": "AlphaFoldDB", "categories": [] }, { "id": "425209", "url": "https://www.ncbi.nlm.nih.gov/gene/425209", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR043596", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043596", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLY5", "url": "https://www.orthodb.org/?gene=A0A8V0ZLY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM89", "url": "https://www.orthodb.org/?gene=A0A8V0ZM89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31183:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31183:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13868", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13868", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422992", "url": 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"MALWRATRGRAFERRREQEARSRLQWESYSRSFARAAICCSAQARWSAPRGPRSPSSGRREAAERLGQRRERLRELLSAERDALEAELQPGRGTEPAGMRERCAELRAAREGRRRQVESELHTKSVAESWGEQLKQKQQQEAMEREERELYENEYEIAQREALERIRQEEEKRQLEDKKQAEMLLQQIEELKLREAEATKLKKEQENLLKQQWELQSLEEERKQMEEHRKKTELGRFLMHQCDAQLKRRAQQIQEELETDRQILLALLEKEGEDQRRQSERRERAVADAAWMRRVIEEQLQLEKEREAELQIIFREEARKVWEKREEQWKKERMARDRLMNEVLAGRQLQIQAKMELNRQAQEESIKHREQLIKELEEAKELTRQEREKEKELKTARRQELEAQLTERRLQEQEKQERQREEEEEERLNKQRCAELVQQEARSMAEQGYCSR", "length": 452, "header": "tr|A0A8V0ZLY5-1|A0A8V0ZM89_CHICK Computationally mapped isoform of Trichoplein keratin filament-binding protein OS=Gallus gallus OX=9031 GN=TCHP PE=1 SV=1 CANONICAL=A0A8V0ZM89-1" }, "locus": { "chromosome": "15", "start_pos": 6869505, "end_pos": 6864802, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052917.1", "url": "https://www.ensembl.org/id/ENSGALT00010052917.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031822.1", "url": 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"ENSGALT00010052920.1", "url": "https://www.ensembl.org/id/ENSGALT00010052920.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031826.1", "url": "https://www.ensembl.org/id/ENSGALP00010031826.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM89" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "apoptotic 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZM10-1", "uniprot_ac": "A0A8V0ZM10", "uniprot_id": "A0A8V0ZM10_CHICK", "mass": { "chemical_mass": 48028.0, "monoisotopic_mass": 48028.0 }, "refseq": { "ac": "NP_001186572", "name": "synaptotagmin-13 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186572" }, "gene_names": [ { "name": "SYT13", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ] }, { "name": "SYT13", "type": "synonym", "evidence": [ { "id": "NP_001186572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186572" } ] }, { "name": "synaptotagmin-13", "type": "synonym", "evidence": [ { "id": "NP_001186572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186572" } ] } ], "protein_names": [ { "name": "Synaptotagmin-13", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10/entry#names_and_taxonomy" } ] }, { "name": "Synaptotagmin XIII", "type": "synonym", "evidence": [ { "id": "A0A8V0ZM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10/entry#names_and_taxonomy" } ] }, { "name": "synaptotagmin XIII", "type": "synonym", "evidence": [ { "id": "NP_001186572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186572" } ] }, { "name": "synaptotagmin-13 precursor", "type": "synonym", "evidence": [ { "id": "NP_001186572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186572" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.140319.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992393 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On May 16, 2014 this sequence version replaced NP_001186572.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186572", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186572" } ] }, { "annotation": "May be involved in transport vesicle docking to the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10#function" }, { "database": "UniProtKB", "id": "ARBA00058123", "url": "https://www.uniprot.org/uniprotkb/ARBA00058123#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYT13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10", "locus": { "chromosome": "5", "start_pos": 21850911, "end_pos": 21868948, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021743", "url": "https://www.ensembl.org/id/ENSGALG00010021743" } ] } } ], "crossref": [ { "id": "A0A8V0ZM10", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZM10", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08677", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08677", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423175", "url": "https://www.ncbi.nlm.nih.gov/gene/423175", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028692", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028692", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423175", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423175", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZM10", "url": "https://www.orthodb.org/?gene=A0A8V0ZM10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024:SF250", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024:SF250", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186572", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186572", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLSAPIIALGATLGTATSILALCGLTCFCKCKQPGKGLSEKDQDEDTENTKPSVLQPAQQFNVKKTAEPVQPRALLKFPNIYGPKPVVTSPEIVNYTQYSLKTTEEPATVKHAVLDENRMKIQVNEELFVLPQNGVVKDVCVTEHLKPERAASCNQVPELRYSLTYDQQKAELCVALLEAMHGKMSSDQDTGCHCYILGTLVSKSGMTEAQTELKKKVLHTLWEEALRFPLTEEEMQEGTLTLTLRNCDKFSRHSIVGELKLSLANMEDFGMAQWERLKTPEKEPSTGHGEVLLSISYLPAANRLLVVIIKAKNLHSKQLKDLLGNDVSVKVTLRHQSLKLKKKQTKHAKHKINPVWNEMIMFEVPHELLRASSVELEMLSQDGAGQSQVLGKCSLGLHVTGTERNHWEEMLRNPRRQIAMWHQLHM", "length": 428, "header": "tr|A0A8V0ZM10-1|A0A8V0ZM10_CHICK Isoform 1 of Synaptotagmin-13 OS=Gallus gallus OX=9031 GN=SYT13 PE=3 SV=1 CANONICAL=A0A8V0ZM10-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZM10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10/entry#A0A8V0ZM10-1", "sequence": { "sequence": "MVLSAPIIALGATLGTATSILALCGLTCFCKCKQPGKGLSEKDQDEDTENTKPSVLQPAQQFNVKKTAEPVQPRALLKFPNIYGPKPVVTSPEIVNYTQYSLKTTEEPATVKHAVLDENRMKIQVNEELFVLPQNGVVKDVCVTEHLKPERAASCNQVPELRYSLTYDQQKAELCVALLEAMHGKMSSDQDTGCHCYILGTLVSKSGMTEAQTELKKKVLHTLWEEALRFPLTEEEMQEGTLTLTLRNCDKFSRHSIVGELKLSLANMEDFGMAQWERLKTPEKEPSTGHGEVLLSISYLPAANRLLVVIIKAKNLHSKQLKDLLGNDVSVKVTLRHQSLKLKKKQTKHAKHKINPVWNEMIMFEVPHELLRASSVELEMLSQDGAGQSQVLGKCSLGLHVTGTERNHWEEMLRNPRRQIAMWHQLHM", "length": 428, "header": "tr|A0A8V0ZM10-1|A0A8V0ZM10_CHICK Isoform 1 of Synaptotagmin-13 OS=Gallus gallus OX=9031 GN=SYT13 PE=3 SV=1 CANONICAL=A0A8V0ZM10-1" }, "locus": { "chromosome": "5", "start_pos": 21868594, "end_pos": 21856439, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052848.1", "url": "https://www.ensembl.org/id/ENSGALT00010052848.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031754.1", "url": "https://www.ensembl.org/id/ENSGALP00010031754.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423175", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423175", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" }, { "name": "dense core granule", "id": "GO:0031045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" }, { "name": "regulation of calcium ion-dependent exocytosis", "id": "GO:0017158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle exocytosis", "id": "GO:2000300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000300", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" }, { "name": "calcium-dependent activation of synaptic vesicle fusion", "id": "GO:0099502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZM10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM10" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 157, "end_pos": 281, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZM22-1", "uniprot_ac": "A0A8V0ZM22", "uniprot_id": "A0A8V0ZM22_CHICK", "mass": { "chemical_mass": 19631.0, "monoisotopic_mass": 19631.0 }, "refseq": { "ac": "NP_001279014", "name": "probable ribosome biogenesis protein RLP24", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001279014" }, "gene_names": [ { "name": "RSL24D1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22" } ] }, { "name": "C10H15ORF15", "type": "synonym", "evidence": [ { "id": "NP_001279014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001279014" } ] }, { "name": "RSL24D1", "type": "synonym", "evidence": [ { "id": "NP_001279014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001279014" } ] } ], "protein_names": [ { "name": "Probable ribosome biogenesis protein RLP24", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22/entry#names_and_taxonomy" } ] }, { "name": "Ribosomal L24 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22/entry#names_and_taxonomy" } ] }, { "name": "probable ribosome biogenesis protein RLP24-like", "type": "synonym", "evidence": [ { "id": "NP_001279014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001279014" } ] }, { "name": "probable ribosome biogenesis protein RLP24", "type": "synonym", "evidence": [ { "id": "NP_001279014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001279014" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX931610.1, CO767499.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX931610.1, CN210189.1, BU338605.1, BU217140.1, BU226849.1 and BU118729.1. On May 30, 2014 this sequence version replaced XP_001232073.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001279014", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001279014" } ] }, { "annotation": "Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZSI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI5#function" }, { "database": "UniProtKB", "id": "ARBA00037035", "url": "https://www.uniprot.org/uniprotkb/ARBA00037035#function" }, { "database": "UniProtKB", "id": "A0A8V0ZM22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RSL24D1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22", "locus": { "chromosome": "10", "start_pos": 8047806, "end_pos": 8038484, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021745", "url": "https://www.ensembl.org/id/ENSGALG00010021745" } ] } } ], "crossref": [ { "id": "A0A8V0ZM22", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZM22", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00472", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00472", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "768911", "url": "https://www.ncbi.nlm.nih.gov/gene/768911", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000988", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000988", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768911", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768911", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TCYFCSG", "url": "https://omabrowser.org/oma/group/TCYFCSG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM22", "url": "https://www.orthodb.org/?gene=A0A8V0ZM22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSI5", "url": "https://www.orthodb.org/?gene=A0A8V0ZSI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10792", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10792", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10792:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10792:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001279014", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001279014", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSI5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRIEKCYFCSGPIYPGHGVMFVRNDCKIFRFCKSKCHKNFKKKRNPRKIRWTKAFRKAAGKELTVDNSFEFEKRRNEPVKYQRELWNKTVDAMKRVEEIKQKRQARFIMNRLKKSKELQKAEDIKEVKQNIHLLRAPHAGKPKQLEEKMVQKLQEDVAMEEDS", "length": 163, "header": "tr|A0A8V0ZM22-1|A0A8V0ZM22_CHICK Isoform 1 of Probable ribosome biogenesis protein RLP24 OS=Gallus gallus OX=9031 GN=RSL24D1 PE=3 SV=1 CANONICAL=A0A8V0ZM22-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZM22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22/entry#A0A8V0ZM22-1", "sequence": { "sequence": "MRIEKCYFCSGPIYPGHGVMFVRNDCKIFRFCKSKCHKNFKKKRNPRKIRWTKAFRKAAGKELTVDNSFEFEKRRNEPVKYQRELWNKTVDAMKRVEEIKQKRQARFIMNRLKKSKELQKAEDIKEVKQNIHLLRAPHAGKPKQLEEKMVQKLQEDVAMEEDS", "length": 163, "header": "tr|A0A8V0ZM22-1|A0A8V0ZM22_CHICK Isoform 1 of Probable ribosome biogenesis protein RLP24 OS=Gallus gallus OX=9031 GN=RSL24D1 PE=3 SV=1 CANONICAL=A0A8V0ZM22-1" }, "locus": { "chromosome": "10", "start_pos": 8045774, "end_pos": 8038533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052858.1", "url": "https://www.ensembl.org/id/ENSGALT00010052858.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031764.1", "url": "https://www.ensembl.org/id/ENSGALP00010031764.1" } ] } }, { "isoform_ac": "A0A8V0ZSI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22/entry#A0A8V0ZSI5-1", "sequence": { "sequence": "KFSPRCDSVLRTPPACCSIFRFCKSKCHKNFKKKRNPRKIRWTKAFRKAAGKELTVDNSFEFEKRRNEPVKYQRELWNKTVDAMKRVEEIKQKRQARFIMNRLKKSKELQKAEDIKEVKQNIHLLRAPHAGKPKQLEEKMVQKLQEDVAMEEDS", "length": 154, "header": "tr|A0A8V0ZSI5-1|A0A8V0ZM22_CHICK Computationally mapped isoform of Probable ribosome biogenesis protein RLP24 OS=Gallus gallus OX=9031 GN=RSL24D1 PE=3 SV=1 CANONICAL=A0A8V0ZM22-1" }, "locus": { "chromosome": "10", "start_pos": 8045774, "end_pos": 8040885, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052856.1", "url": "https://www.ensembl.org/id/ENSGALT00010052856.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031762.1", "url": "https://www.ensembl.org/id/ENSGALP00010031762.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768911", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768911", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3GRJ5-1", "protein_name": "Probable ribosome biogenesis protein RLP24", "gene_name": "Rsl24d1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRIEKCYFCSGPIYPGHGMMFVRNDCKVFRFCKSKCHKNFKKKRNPRKVRWTKAFRKAAGKELTVDNSFEFEKRRNEPVKYQRELWSKTIDAMKRVEEIKQKRQAKFIMNRLKKNKELQKVQDIKEVKQNIHLIRAPLAGKGKQLEEKMVQQLQEDVDMEDTS", "length": 163 }, "evidence": [ { "id": "A0A8V0ZM22", "url": "https://omabrowser.org/oma/group/A0A8V0ZM22/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O22165-1", "protein_name": "Probable ribosome biogenesis protein RLP24", "gene_name": "RPL24C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRLEKCWFCSSTIYPGHGIQFVRNDAKIFRFCRSKCHKNFKMKRNPRKVKWTKAFRAAHGKDMTKDTTFEFEKKRNRPERYDRNVTENTLMAIKKIAKIRTAREAKHIENRLKPNKQKKLNDDMKELDQNIHMVQAPGAQKIKVDVSEKKSVQNEAMEE", "length": 159 }, "evidence": [ { "id": "A0A8V0ZM22", "url": "https://omabrowser.org/oma/group/A0A8V0ZM22/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q3SZ12-1", "protein_name": "Probable ribosome biogenesis protein RLP24", "gene_name": "RSL24D1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRIEKCYFCSGPIYPGHGMMFVRNDCKVFRFCKSKCHKNFKKKRNPRKVRWTKAFRKAAGKELTVDNSFEFEKRRNEPVKYQRELWNKTIDAMKRVEEIKQKRQAKFIMNRLKKNKELQKVQDVKEVKQNIHLIRAPLAGKGKQLEDKMVQKLQEDVDMEDVS", "length": 163 }, "evidence": [ { "id": "A0A8V0ZM22", "url": "https://omabrowser.org/oma/group/A0A8V0ZM22/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7ZTZ2-1", "protein_name": "Probable ribosome biogenesis protein RLP24", "gene_name": "rsl24d1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRIEKCYFCSAPVYPGHGMMFVRNDCKVFRFCRSKCHKNFKKKRNPRKTRWTKAFRKSAGKELTVDNSLEFEKRRNTPVKYNRELWSKTVEAMRKVESIKHKRQARFIMNRLKKGKELEKAADISEVKKNIHLIKAPHAGQAKQLEDKMVQKLAEDVEMDE", "length": 161 }, "evidence": [ { "id": "A0A8V0ZM22", "url": "https://omabrowser.org/oma/group/A0A8V0ZM22/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86B05-1", "protein_name": "Probable ribosome biogenesis protein RLP24", "gene_name": "rlp24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRIEKCYFCSGPVYPGHGVMFVRNDCKQFRFCRSKCHKNFKLKRNPRKTRWTKAFRKLNGKEMTVDKTLEFEKKRNRPVKYDRELINNTIIAMARVQKIKERREKTFYKNRMEGVKGMQKKQKLKEINQNLSLIRGPSALNKLQERIKNNAEKIEQLTTTKMQS", "length": 164 }, "evidence": [ { "id": "A0A8V0ZM22", "url": "https://omabrowser.org/oma/group/A0A8V0ZM22/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q99L28-1", "protein_name": "Probable ribosome biogenesis protein RLP24", "gene_name": "Rsl24d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIEKCYFCSGPIYPGHGMMFVRNDCKVFRFCKSKCHKNFKKKRNPRKVRWTKAFRKAAGKELTVDNSFEFEKRRNEPVKYQRELWNKTIDAMKRVEEIKQKRQAKFIMNRLKKNKELQKVQDIKEVKQNIHLIRAPLAGKGKQLEEKMVQQLQEDVDMEEAS", "length": 163 }, "evidence": [ { "id": "A0A8V0ZM22", "url": "https://omabrowser.org/oma/group/A0A8V0ZM22/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHA3-1", "protein_name": "Probable ribosome biogenesis protein RLP24", "gene_name": "RSL24D1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRIEKCYFCSGPIYPGHGMMFVRNDCKVFRFCKSKCHKNFKKKRNPRKVRWTKAFRKAAGKELTVDNSFEFEKRRNEPIKYQRELWNKTIDAMKRVEEIKQKRQAKFIMNRLKKNKELQKVQDIKEVKQNIHLIRAPLAGKGKQLEEKMVQQLQEDVDMEDAP", "length": 163 }, "evidence": [ { "id": "A0A8V0ZM22", "url": "https://omabrowser.org/oma/group/A0A8V0ZM22/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VGN9-1", "protein_name": "Probable ribosome biogenesis protein RLP24", "gene_name": "RpL24-like", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRIQTCYFCSSKIYPGHGVQFVRNDCKVFKFCRGKCHKAFKRKKNPRKVGWTKAYRKAAGKELAIDPSFEFEKRRNVPMKYSRETWQKGLEAIKRVTEIKEKRTSHFVMERLRKGRQVEIQMDVKDVQRNMSLIRSPAAGLKQRRAQEAAEEAALMEEDLPEEKITYVDARELEKKLEEGMGVEDLEMLEA", "length": 191 }, "evidence": [ { "id": "A0A8V0ZM22", "url": "https://omabrowser.org/oma/group/A0A8V0ZM22/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ribosomal large subunit biogenesis", "id": "GO:0042273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042273", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM22" }, { "id": "SM00746", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRASH", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 44, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM132C", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26", "locus": { "chromosome": "15", "start_pos": 3826002, "end_pos": 3977129, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020787", "url": "https://www.ensembl.org/id/ENSGALG00010020787" } ] } } ], "crossref": [ { "id": "A0A8V0ZM26", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZM26", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026307", "url": 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Classification" ] }, { "id": "IPR055424", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055424", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZM26", "url": "https://www.orthodb.org/?gene=A0A8V0ZM26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13388:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13388:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15706", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15706", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16070", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16070", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23486", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23486", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZM26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQEQMRGPSNTVSKLWRWPFPNAFEECRRNPLRCLGNCATLYVAESRGVLDSNQRFSSSPTYLPVSYRIFSAETSFFLKEANQDFMRNSSLQSRVESFFPYKAKRPPVLNASYGPFSIEQVVPQDLMITSSLFGSANKFTYNWKLKAFIMSDKIYPSKPKVQVLFYIVGRDWDDYSTTERLPCLRVFAFRETREVRGSCRLKGDLGLCVAELELLPGWFNPPTVVTGRKKPLDLSEGSPVELYYTVQPGDEKGECTAEDVRKGNAIRPGKDGMDETMSHLQRIGSISLYRGQETSQLTELRLDGNIVIWLPSKPVKQGEVVNVYVTIANNSTVDQFILRAKVKKGVNILNAKTSDPQQWDVKQEVGNGGKHSTTTVICQRMAPSSRNRSNSLFNEVVQMDFEIASFSSLSGTQPITWQVEYPRKGTTDITLSEIFICQKDLVGIVPLAMDTEIVNTAILTGKTVAVPIKVVSIEENSAVTDISESVECKSSDEDVIKVSDRCDYVYVNGKEMKGKVNVLVNFTYQYLSAPLQITVWVPRLPLQIDISDTELSQIKGWRVPVVSNKRPTRDSDDEDEDERKGRGCTLQYQHAMVRVLTQFVAEDSSPWGQLSYLLGSDWQFDITDLVMDFMKLEEPHIAKLQEGRILIGREVGMTTMQVLSPLSDSILAEKTVTVLDDKVTITDLGVQLVAGLSLFLQPSAASSRAIVATTVAQELLHTPKQEAVVSTWIQFSDSSVTPLDIYDSKDFSLSAVSLDEAVVSVHQNAALKWPVVVAEGEGQGTLIKVDMMISEACQKSKRKSILAVGNGNIKVKFGQNDADSDTGGDYDGEEIENHASDRRHKVSDQERYGQEGRYYGGSSAEREESTIRKVGTTAKSVIKNKVIKNNKLDGGKLSDDSQLQNIPIDFTNFPAQVDLPKGNAGMEENDLVQTPRGLSDLEIGMYALLGVFCLAILVFLINCATFALKYRHKQVLVEGQTTMTHSHDWVWLGNEAELLENTADALPQQDEHTTIIDRGMGCEESNQLLNGSAQKNIQSQIHRSADSGGKLVKEQKSEPLHSPTSKRKRVKFTTFTTIPPDDGCPTVNSILSSNDDDIKWVCQDMDLGDSKEIRNYMEKLKDKV", "length": 1120, "header": "tr|A0A8V0ZM26-1|A0A8V0ZM26_CHICK Isoform 1 of Transmembrane protein 132C OS=Gallus gallus OX=9031 GN=TMEM132C PE=3 SV=1 CANONICAL=A0A8V0ZM26-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZM26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26/entry#A0A8V0ZM26-1", "sequence": { "sequence": 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"length": 1120, "header": "tr|A0A8V0ZM26-1|A0A8V0ZM26_CHICK Isoform 1 of Transmembrane protein 132C OS=Gallus gallus OX=9031 GN=TMEM132C PE=3 SV=1 CANONICAL=A0A8V0ZM26-1" }, "locus": { "chromosome": "15", "start_pos": 3977125, "end_pos": 3826402, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050280.1", "url": "https://www.ensembl.org/id/ENSGALT00010050280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029711.1", "url": "https://www.ensembl.org/id/ENSGALP00010029711.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1026, "end_pos": 1028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26" }, { "id": "PF15706", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15706" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 C-terminal", "eco_id": "ECO_0000259", "start_pos": 908, "end_pos": 993, "start_aa": "Asn", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26" }, { "id": "PF15705", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15705" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 N-terminal", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 127, "start_aa": "Val", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26" }, { "id": "PF23039", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23039" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 cohesin-like", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 441, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26" }, { "id": "PF23486", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23486" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 fifth", "eco_id": "ECO_0000259", "start_pos": 543, "end_pos": 679, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26" }, { "id": "PF23481", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23481" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 second Ig-like", "eco_id": "ECO_0000259", "start_pos": 144, "end_pos": 282, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26" }, { "id": "PF23487", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23487" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein TMEM132 sixth", "eco_id": "ECO_0000259", "start_pos": 680, "end_pos": 795, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZM26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM26" }, { "id": "PF16070", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16070" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein family 132 fourth", "eco_id": "ECO_0000259", "start_pos": 443, "end_pos": 540, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1026, "end_pos": 1028 }, { "start_pos": 110, "end_pos": 112 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZM27-1", "uniprot_ac": "A0A8V0ZM27", "uniprot_id": "A0A8V0ZM27_CHICK", "mass": { "chemical_mass": 46366.0, "monoisotopic_mass": 46366.0 }, "refseq": { "ac": "XP_040560270", "name": "cell division cycle-associated protein 7 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560270" }, "gene_names": [ { "name": "CDCA7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM27" } ] }, { "name": "CDCA7", "type": "synonym", "evidence": [ { "id": "XP_040560270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560270" } ] } ], "protein_names": [ { "name": "Cell division cycle associated 7", "type": "synonym", "evidence": [ { "id": "A0A8V0ZM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM27/entry#names_and_taxonomy" } ] }, { "name": "cell division cycle-associated protein 7 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040560270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040560270" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025007105.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025007105", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007105" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM52" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POLD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM52", "locus": { "chromosome": "5", "start_pos": 136623, "end_pos": 137476, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023262", "url": "https://www.ensembl.org/id/ENSGALG00010023262" } ] } } ], "crossref": [ { "id": "A0A8V0ZM52", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZM52", "database": "AlphaFoldDB", "categories": [] }, { "id": "112532567", 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"categories": [ "Protein Classification" ] }, { "id": "PF04081", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04081", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-110314", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110314", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174411", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174411", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174414", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174414", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174417", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174417", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-174437", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174437", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5358565", 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"MERAGRITDSFPRRHRARTRTDGKERSGTRRGRGAEGRHREVPPAPPPPNPPRAEPEDARDPPAPTREAPRELLEMLRRFDLAWEYGPCSGITRLQRWERARALGLSPPAAVRDALLEHRDDPAVTYSLWHEYGL", "length": 135, "header": "tr|A0A8V0ZM52-1|A0A8V0ZM52_CHICK Isoform 1 of DNA polymerase delta 4, accessory subunit OS=Gallus gallus OX=9031 GN=POLD4 PE=4 SV=1 CANONICAL=A0A8V0ZM52-1" }, "locus": { "chromosome": "5", "start_pos": 137277, "end_pos": 136721, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056719.1", "url": "https://www.ensembl.org/id/ENSGALT00010056719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034461.1", "url": "https://www.ensembl.org/id/ENSGALP00010034461.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:112532567", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:112532567", "resource": "KEGG Pathway" }, { "id": "R-GGA-110314", "name": "", "url": 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"https://www.reactome.org/PathwayBrowser/#R-GGA-5358565", "resource": "Reactome", "description": "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" }, { "id": "R-GGA-5358606", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5358606", "resource": "Reactome", "description": "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" }, { "id": "R-GGA-5651801", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5651801", "resource": "Reactome", "description": "PCNA-Dependent Long Patch Base Excision Repair" }, { "id": "R-GGA-5656169", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" }, { "id": "R-GGA-5685942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5685942", "resource": "Reactome", "description": "HDR through Homologous Recombination (HRR)" }, { "id": "R-GGA-5693537", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5693537", "resource": "Reactome", "description": "Resolution of D-Loop Structures" }, { "id": "R-GGA-5696397", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696397", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in GG-NER" }, { "id": "R-GGA-5696400", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696400", "resource": "Reactome", "description": "Dual Incision in GG-NER" }, { "id": "R-GGA-6782135", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782135", "resource": "Reactome", "description": "Dual incision in TC-NER" }, { "id": "R-GGA-6782210", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6782210", "resource": "Reactome", "description": "Gap-filling DNA repair synthesis and ligation in TC-NER" }, { "id": "R-GGA-69091", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69091", "resource": "Reactome", "description": "Polymerase switching" }, { "id": "R-GGA-69166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69166", "resource": "Reactome", "description": "Removal of the Flap Intermediate" }, { "id": "R-GGA-69183", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69183", "resource": "Reactome", "description": "Processive synthesis on the lagging strand" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "delta DNA polymerase complex", "id": "GO:0043625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM52" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA synthesis involved in DNA repair", "id": "GO:0000731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000731", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM52" } ], "pmid": "" }, { "name": "DNA-templated DNA replication", "id": "GO:0006261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006261", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A8V0ZM69_CHICK", "mass": { "chemical_mass": 124376.0, "monoisotopic_mass": 124376.0 }, "refseq": { "ac": "XP_004941715", "name": "mitotic deacetylase-associated SANT domain protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941715" }, "gene_names": [ { "name": "ELMSAN1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" } ] }, { "name": "ELMSAN1", "type": "synonym", "evidence": [ { "id": "XP_004941715", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941715" } ] } ], "protein_names": [ { "name": "Mitotic deacetylase associated SANT domain protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69/entry#names_and_taxonomy" } ] }, { "name": "mitotic deacetylase-associated SANT domain protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004941715", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941715" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004941715.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004941715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004941715" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ELMSAN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZM69", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZM69", "database": "AlphaFoldDB", "categories": [] }, { "id": "423245", "url": "https://www.ncbi.nlm.nih.gov/gene/423245", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423245", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423245", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TAKCGVE", "url": 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[ "Protein" ] }, { "id": "A0A8V0ZM69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1116, "header": "tr|A0A8V0ZM69-1|A0A8V0ZM69_CHICK Isoform 1 of Mitotic deacetylase associated SANT domain protein OS=Gallus gallus OX=9031 GN=ELMSAN1 PE=4 SV=1 CANONICAL=A0A8V0ZM69-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZM69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69/entry#A0A8V0ZM69-1", "sequence": { "sequence": "MNLQAQQKSSTKRTGKRITYFNEQDITVSSKEPQQQLKEGQYYGHGGNIPASQTMEIPHTAGLTSATSNVALMNSVYSQDRGESMMMSQPVTAVKWQNSLMGNRLPERGDTHWQSPSAMWNHSMVFGSNPKGPHANAGAPGFYGHPEALKRNQEKGVFVSQMDLYEDAVQQMMSQKAQLEQQALVRQQAQINSFHQMQKQQQQNQSLPLQPFQLAFGHQGQKQGLPELLHVFQEAPASSTPAFTAQQKQQALPQLQLFENFYPQQQQQQQAATQAFGLQQTTSIAQPHVAAAAPQHHMMAHQFQQTERNQELFKALTEQNQQTVLPQTQIPFPRRSRRLSKEGVLVTSTGEALAAKQAEEQSGNLFLHHWQTHQQEVPLQQPLESLTHNKSSYSHPKRMDQGQKDVLANSELCHVETDRHTIAQNGRDAEKQTVAAEENAPRTNDFQGVRGGVIQSTRRRRRVSQEANLLTLAQKAVELASLQDVKESDTSEDKKSVLIAAPGPTAAKSVVEFASSSPAPKKAREDSSLVPLIIPVSVPVRKIDLQNLEKEKSEDGKLQRGQTNDRTPCERKPSVIVTRRRSNRNTNMETSNQHEHAVPKDETEGFARKPKQRPRPEPLFIPPKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSDRNFELPPYTPPPILSPVREGSGLYFNAILSSSGHPVPPPMTPKSSHRTLLRSNSSEVTPPVLSVVGEATPVSIEPRINVGTRFQAEIPSLQDRSLAAADEHKAELVWQPWGDLETNRVTQQNVESLLAAACSSIFPGGGTNQELALHFLHEEKGSVLGALSKLLLKGPVRSSTHPLADYHYTGSDSWKVAEKKLFNKGIAIYKKDFFLVQKLIKTKTVAQCVEFYYTYKKQVKIGRNGTLIFGDIDVANEKSVRDEAEVDIKSSHRFARVLPLRRDFFSEEQGHLEEEEEEAEEAEEGLDNRKKSTLLFKDEQTLQDDLIASDANIRSREATVTGRIGRRPRETTMKPRKLIPAPVQRRRRKQKMKSDVTSKIQNTENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALKQQEREAAAAAEAAAAAAHSQAQQEESSESGSNSSGSSSGSSDEDGEI", "length": 1116, "header": "tr|A0A8V0ZM69-1|A0A8V0ZM69_CHICK Isoform 1 of Mitotic deacetylase associated SANT domain protein OS=Gallus gallus OX=9031 GN=ELMSAN1 PE=4 SV=1 CANONICAL=A0A8V0ZM69-1" }, "locus": { "chromosome": "5", "start_pos": 25666655, "end_pos": 25648389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050409.1", "url": "https://www.ensembl.org/id/ENSGALT00010050409.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029761.1", "url": "https://www.ensembl.org/id/ENSGALP00010029761.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 240, "start_aa": "Thr", "end_pos": 240, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr240", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 505, "start_aa": "Thr", "end_pos": 505, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr505", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423245", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423245", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACA6-1", "protein_name": "Mitotic deacetylase associated SANT domain protein", "gene_name": "Mideas", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNLQAQSKAQNKRKRCPYGDQEPAAKEQPPPLQAPPQSLRAKEEQYGPHEGPAGVASTTQPVELSPPNNLALLNSVVYGSERTTAAMLSQQAQVSSVKWPNSVMTPGRGLECGGGAGISDSGWQQQPGQPPPHSTWNHLPLYSGPKGGPHPGVGVSPYYNHAEALKGNKPGGPQLDHYGNAVQPMVPQKMQLEVGRPQAPLNSYHSAKKPPNQTLPLQPFQLAFGHQVNRQVFRQGPQPSNPTTSFPPQKQQQQQQQQQPPAALPHMQLFENYYPMHQPPSQQHQDFTLAPGGPLGQTHLPHRGMAPYPFPHNPELRKALLQDPASQPVLPQPQMAFPRRSRRLSKEGILPSNSLDGAGTQPGQEPTSNLFLHHWSLQQPPPGALGQPHSEALGFPLELRESQLLVDGDRLAPNGREREAPAVGNEEVSRAGGLGDCGQMMRSGVIQSTRRRRRASQEANLLTLAQKAVELASLQDANGSEEKRKSVLASTAKCGVEFSEPASAAKRAREESGMVPLIIPVSVPVRTVGPTEVAQVGGSDEDGKGLEQFPTDHKPSVIVTRRRSTRVPGTDTAAQAEDLNAKLEGEPSMRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYFNAILSTSNVPAPPPITPKSAHRTLLRSNSSEVTPPVLSVMGEATPVSIEPRINVGTRFQAEIPTMRDRSLAAADPHKADLVWQPWEHLESSWEKQRQVDDLLTAACSSIFPGAGTNQELALHYLHESRGDILEALNKLLLKKPLRPHNHPLATYHYTGSDEWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDLDTGAEKSGQEEVEVDVKTSQKFPRVLPPRRESPSEERLEPKREMKEPKKEGEEEVPDTQEKGEQEEGRERSRRAAAVKATQTLQPTEAANDVLILRSHEPNAPGSASVQTSEKPREGPGKSRRALPFTEKKKKPEAFNKTQNQENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALRLKEKEAAAAAAHQQALKEESGEGEKG", "length": 1089 }, "evidence": [ { "id": "A0A8V0ZM69", "url": "https://omabrowser.org/oma/group/A0A8V0ZM69/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BI11-1", "protein_name": "Mitotic deacetylase associated SANT domain protein", "gene_name": "MIDEAS", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLQAQPKAQNKRKRCLFGDQEPAPKEQPQPLQAPQQPPAPPQSRVKEEPYFAHEGSAGAAPHSQPVELPSSNSLALLNSVVYGSERTMLSQQVGSVKWPNSVMAPGRGPERGGGGGVSDSGWQQQPGQPPPNSTWNRHSLPLYSGPKGSSHPGMGVATYYNHPEPLKLEKVGGPQLDRYGNAVRPMVPPKVQLEVGRSQAPLNSFHMAKKPPNQTLPLESFRQAFGHQVNRQVFRQGPPPPNPVTAFPPQKQQQQQQQQQAALPQIQLLENFYSMQQPPPSQQPQDFGLQPAGPLGQSHLAHHSMAPYHFPPNPDMNPELRKALLQESAPQPVLPQAQIAFPRRSRRLSKEGVLPSTALDGAGTQPGQEPASNLFLHHWVPQQPPPGPLGQPHPEALGFTLELRESQFLSDGERLAPNGRERETPAMGGEEGMRAVGTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQNTKDASGSEEKRKSVLASTTKCGVEFSEPALAKRAREDSGMVPLIIPVSVPVRAVDPTEAAQAGGVDEDGKGPEQHPAEHKPSVIVTRRRSTRIPGTDAPAQPEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYFNAIMSTSSIPAPPPITPKSAHRTLLRSNSAEVTPPVLSVMGEATPVSIEPRINVGSRFQAEIPSMRDRALAAADPHKADLVWQPWEVLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPPPRRESPNEERLEPKKEEKETRKEGEEEMPETQDKGEQEEGRERSRRAAAVKATQTLQANESANDILILRSHESNAPGSAGGQASEKPREGPGKSRRALPFSEKKKKTETFNKTQNQENTFPCKKCGRVFFKVKSRSAHMKSHAEQEKKAAALRQKEKEAAAAAATAAASPHQPALREESGAGERG", "length": 1102 }, "evidence": [ { "id": "A0A8V0ZM69", "url": "https://omabrowser.org/oma/group/A0A8V0ZM69/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9Q2I4-1", "protein_name": "Mitotic deacetylase associated SANT domain protein", "gene_name": "Mideas", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLQAQSKAQSKRKRCPFGDQEPAAKEQPPPLQSPPQSLRAKEEQYGAHEGPTGVASTTQPVELSPPNNLALLNSVVYGSERTTAAMLSQQAQVSSVKWPSSVMAPGRGLERGGGGGISDSGWQQQPGQPPPHSTWNHLPLYGGPKGSPHPGVGVPPYYNHPEALKGNKPGGPQLDHYGNAVQPMVPQKVQLEVGRPQAPLNSFHAAKKPPNQTLPLQPFQLAFGHQVNRQVFRQGPQPSNPTASFPPQKQQQQQQPAALPQMQLFENYYPMHQLPSQQHQDFGLAPGGPLGQTHLAHRSMAPYPFSHNPDMNPELRKALLQDPASQPVLPQPQMAFPRRSRRLSKEGILPSNSLDGAGTQPGQEPASNLFLHHWSLPQPPPGTLGQPHSEALGFPLELRESQMLADGDRLAPNGREREPPAMGNEEVMRAGGLGDCGQMIRSGVIQSTKRRRRVSQEANLLTLAQKAVELASMQDANGSEEKRKSVLATTSRCGVEFSEPALAAKRAREESGMVPLIIPVSVPVRTVGPTEVAQVGGADEDGTGLEQYPTEHKPSVIVTRRRSTRVPGTDAAAQAEDLNVKLEGEPSMRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFEPPPYTPPPILSPVREGSGLYFNAIISTSNIPAPPPITPKSAHRTLLRSNSSEVTPPVLSVMGEATPVSIEPRINVGTRFQAEIPMMRDRALAAFDPHKADLVWQPWEHLESSWEKQRQVDDLLTAACSSIFPGAGTNQELALHYLHESRGDILEALNKLLLRKPLRPHNHPLATYHYTGSDQWKTAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDLDIGDEKSGQEEVEVDVKTSQKFPRVPPPRRESPSEERLEPKREVTEPRKEGEEEVPDTQEKGEQEEGRERCRRAAAVKATQTLQANEAANDVLILRSHEPNAPGSAGIQTSEKPREGPGKSRRALPFTEKKKKAEAFNKTQNQENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALRLKEKEAAAAAAHQQALREESGEGEKG", "length": 1089 }, "evidence": [ { "id": "A0A8V0ZM69", "url": "https://omabrowser.org/oma/group/A0A8V0ZM69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1S3I8-1", "protein_name": "Mitotic deacetylase associated SANT domain protein", "gene_name": "MIDEAS", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLQAQPKAQNKRKRCLFGDQEPAPKEQPQALQAPQQPPAPPQSTRVKEEPYFGQEGPAGAVPASQPVELPPPNSLALLNSVVYGSERTMLSQQMGSVKWPNSVMAPGRGPERGGGGGVSDSGWQQQPGQPPPHSTWNRHSLPLYSGPKGSPHPGMGVSTYYNHPEALKREKGGGPQLDRYGNAVRPMMPQKVQLDVGQPQAPLNSFHVAKKPPNQTLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQQAALPQMQLFDNFYPMQQPPSQQPQDFGLQPGGPLGQSHLAHHSMAPYPFPPNPDLNPELRKALLQESAPQPVLPQAQIAFPRRSRRLSKEGVLPSTALDGAGTQPGQEPASNLFLHHWPPQQPPPGPLGQPHPEALRFPLELRESQLLSDGDRLAPNGRERDAPAMGNEEGVRAVGTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQNTKDANGSEEKRKSVLASTAKCGVEFSEPSLAAKRAREDSGMVPLIIPVSVPVRAVDPTEAAQAGGVDEDGRGPEQNPAEHKPSVIVTRRRSTRIPGTDAPAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPLSPVREGSGLYFNAIMSTSSIPAPPPITPKSAHRTLLRSNSAEVTPPVLSVMGEATPVSIEPRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWENLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILEALNKLLLKKPLRPHNHPLATYHYTGSDQWKAAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPPPRRESPSEERLEPRKEVKETRKEGEEELPETQEKGEQEEGRERSRRAAAVKATQTLQANESANDILILRSHESNAPGSAGCQASEKPREGPGKSRRALPFSEKKKKPETFNKTQNQENTFPCKKCGRVFYKVKSRSAHMKSHAEQEKKAAALRQKEKEAAAAAATVAAASPHQPALREESGAGERG", "length": 1101 }, "evidence": [ { "id": "A0A8V0ZM69", "url": "https://omabrowser.org/oma/group/A0A8V0ZM69/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6PJG2-1", "protein_name": "Mitotic deacetylase-associated SANT domain protein", "gene_name": "MIDEAS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNLQAQPKAQNKRKRCLFGGQEPAPKEQPPPLQPPQQSIRVKEEQYLGHEGPGGAVSTSQPVELPPPSSLALLNSVVYGPERTSAAMLSQQVASVKWPNSVMAPGRGPERGGGGGVSDSSWQQQPGQPPPHSTWNCHSLSLYSATKGSPHPGVGVPTYYNHPEALKREKAGGPQLDRYVRPMMPQKVQLEVGRPQAPLNSFHAAKKPPNQSLPLQPFQLAFGHQVNRQVFRQGPPPPNPVAAFPPQKQQQQQQPQQQQQQQQAALPQMPLFENFYSMPQQPSQQPQDFGLQPAGPLGQSHLAHHSMAPYPFPPNPDMNPELRKALLQDSAPQPALPQVQIPFPRRSRRLSKEGILPPSALDGAGTQPGQEATGNLFLHHWPLQQPPPGSLGQPHPEALGFPLELRESQLLPDGERLAPNGREREAPAMGSEEGMRAVSTGDCGQVLRGGVIQSTRRRRRASQEANLLTLAQKAVELASLQNAKDGSGSEEKRKSVLASTTKCGVEFSEPSLATKRAREDSGMVPLIIPVSVPVRTVDPTEAAQAGGLDEDGKGPEQNPAEHKPSVIVTRRRSTRIPGTDAQAQAEDMNVKLEGEPSVRKPKQRPRPEPLIIPTKAGTFIAPPVYSNITPYQSHLRSPVRLADHPSERSFELPPYTPPPILSPVREGSGLYFNAIISTSTIPAPPPITPKSAHRTLLRTNSAEVTPPVLSVMGEATPVSIEPRINVGSRFQAEIPLMRDRALAAADPHKADLVWQPWEDLESSREKQRQVEDLLTAACSSIFPGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKIGRNGTLTFGDVDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPEIQEKEEQEEGRERSRRAAAVKATQTLQANESASDILILRSHESNAPGSAGGQASEKPREGTGKSRRALPFSEKKKKTETFSKTQNQENTFPCKKCGR", "length": 1045 }, "evidence": [ { "id": "A0A8V0ZM69", "url": "https://omabrowser.org/oma/group/A0A8V0ZM69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" } ], "pmid": "" }, { "name": "histone deacetylase complex", "id": "GO:0000118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000118", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZM69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1101, "end_pos": 1103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 893, "end_pos": 895, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 1036, "end_pos": 1063, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" }, { "id": "PS51156", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELM2", "eco_id": "ECO_0000259", "start_pos": 731, "end_pos": 823, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM69" }, { "id": "PS51293", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51293" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SANT", "eco_id": "ECO_0000259", "start_pos": 838, "end_pos": 889, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 240, 505 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1101, "end_pos": 1103 }, { "start_pos": 121, "end_pos": 123 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 636, "end_pos": 638 }, { "start_pos": 709, "end_pos": 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"database": "Ensembl Gene", "id": "ENSGALG00010023287", "url": "https://www.ensembl.org/id/ENSGALG00010023287" } ] } } ], "crossref": [ { "id": "A0A8V0ZMA8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000021079", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000021079", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08745", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08745", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374070", "url": "https://www.ncbi.nlm.nih.gov/gene/374070", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374070", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374070", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EANQHMV", "url": "https://omabrowser.org/oma/group/EANQHMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMA8", "url": "https://www.orthodb.org/?gene=A0A8V0ZMA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NJM4", "url": "https://www.orthodb.org/?gene=F1NJM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10845", "database": "PANTHER", "categories": [ 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"length": 205, "header": "tr|A0A8V0ZMA8-1|A0A8V0ZMA8_CHICK Isoform 1 of Regulator of G-protein signaling 20 OS=Gallus gallus OX=9031 GN=RGS19 PE=4 SV=1 CANONICAL=A0A8V0ZMA8-1" }, "locus": { "chromosome": "20", "start_pos": 9690320, "end_pos": 9688311, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056787.1", "url": "https://www.ensembl.org/id/ENSGALT00010056787.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034524.1", "url": "https://www.ensembl.org/id/ENSGALP00010034524.1" } ] } }, { "isoform_ac": "F1NJM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMA8/entry#F1NJM4-1", "sequence": { "sequence": "MSRHETSPTTVQPASNHRPNACCFCWCCCCSCSWNEDRERAWRASRETKLETIPNCEACSKPTTEEVRGWAQSFDKLMKSPAGRNVFREFLRTEYSEENMLFWLACEELKTECNKHTIDEKARTIYEDYISILSPKEVSLDSRVREVINRKMQEPSSHTFDDAQLQIYTLMHRDSYPRFLNSAIYKSLLQNVSRSSSES", "length": 199, "header": "tr|F1NJM4-1|A0A8V0ZMA8_CHICK Computationally mapped isoform of Regulator of G-protein signaling 20 OS=Gallus gallus OX=9031 GN=RGS19 PE=4 SV=2 CANONICAL=A0A8V0ZMA8-1" }, "locus": { "chromosome": "20", "start_pos": 9690320, "end_pos": 9686834, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056795.1", "url": "https://www.ensembl.org/id/ENSGALT00010056795.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034530.1", "url": "https://www.ensembl.org/id/ENSGALP00010034530.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:374070", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374070", "resource": "KEGG Pathway" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" 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"recommended", "evidence": [ { "id": "A0A8V0ZME5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME5" } ] } ], "protein_names": [ { "name": "Parathymosin", "type": "synonym", "evidence": [ { "id": "A0A8V0ZME5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTMS", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZME5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZME5", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0ZME5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZME5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEKRVEEAPAELSAKEMKEKKEKLEEKAVHKEKKKEVVEVRMKKMELKRMRKRILRMWMKKKVVTRMTKEMRMGKSRTDMQKNDLQRRRRMKWIQRGRRQKMGPPLESSPPISSVPSISPPPFQPVLALSISLWLHTISDEERLEKLSNREYSSFLPIQRSSPSMMFPT", "length": 170, "header": "tr|A0A8V0ZME5-1|A0A8V0ZME5_CHICK Isoform 1 of Parathymosin OS=Gallus gallus OX=9031 GN=PTMS PE=4 SV=1 CANONICAL=A0A8V0ZME5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZME5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZME5/entry#A0A8V0ZME5-1", "sequence": { "sequence": "MSEKRVEEAPAELSAKEMKEKKEKLEEKAVHKEKKKEVVEVRMKKMELKRMRKRILRMWMKKKVVTRMTKEMRMGKSRTDMQKNDLQRRRRMKWIQRGRRQKMGPPLESSPPISSVPSISPPPFQPVLALSISLWLHTISDEERLEKLSNREYSSFLPIQRSSPSMMFPT", "length": 170, "header": "tr|A0A8V0ZME5-1|A0A8V0ZME5_CHICK Isoform 1 of Parathymosin OS=Gallus gallus OX=9031 GN=PTMS PE=4 SV=1 CANONICAL=A0A8V0ZME5-1" }, "locus": { "chromosome": "1", "start_pos": 77130619, "end_pos": 77128042, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056844.1", "url": "https://www.ensembl.org/id/ENSGALT00010056844.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034559.1", "url": "https://www.ensembl.org/id/ENSGALP00010034559.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMF0-1", "uniprot_ac": "A0A8V0ZMF0", "uniprot_id": "A0A8V0ZMF0_CHICK", "mass": { "chemical_mass": 54703.0, "monoisotopic_mass": 54703.0 }, "refseq": { "ac": "XP_416510", "name": "lymphocyte activation gene 3 protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416510" }, "gene_names": [ { "name": "LAG3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0" } ] }, { "name": "LAG3", "type": "synonym", "evidence": [ { "id": "XP_416510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416510" } ] } ], "protein_names": [ { "name": "Lymphocyte activation gene 3 protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0/entry#names_and_taxonomy" } ] }, { "name": "lymphocyte activation gene 3 protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_416510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416510" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_416510.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_416510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416510" } ] }, { "annotation": "May function as a ligand for MHC class II (MHC-II) on antigen-presenting cells (APC), promoting APC activation/maturation and driving Th1 immune response.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0#function" }, { "database": "UniProtKB", "id": "ARBA00057112", "url": "https://www.uniprot.org/uniprotkb/ARBA00057112#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LAG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0", "locus": { "chromosome": "1", "start_pos": 77151690, "end_pos": 77145736, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023324", "url": "https://www.ensembl.org/id/ENSGALG00010023324" } ] } } ], "crossref": [ { "id": "A0A8V0ZMF0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "418287", "url": "https://www.ncbi.nlm.nih.gov/gene/418287", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LWVAPVE", "url": "https://omabrowser.org/oma/group/LWVAPVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMF0", "url": "https://www.orthodb.org/?gene=A0A8V0ZMF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11422", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11422:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11422:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_416510", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_416510", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPVSPVLFLTLLAVNAGNILPGAAEVENRGQKVWAREGSSALLPCYLSPRKHGKSRKHLSGRTSVLWKRHGASAPQELHVVLEVEYTGLRKTALPMRPRVSVLDSALRNGNFSLCINPVRSDDVGLYEAQVAYNTEILSCQVELGVVTVTLSPPLPVVENEPLLLSCNSSHQASLVETCWFHNGRPVLISGAFCSSHGALYILRPTVSDSGSWHCQLRYADNEIISATYNLQILGFDGPTNPVVYAAAGSAADLPCTLNYLPSASGIRVVKAHWSHFAGGHLQNWSILQNQSSRNFPLHLPVVGPGDAGRYCCAVTVGNKMLSRDMTLAVITVTPRIQGPVSEGSHLLLTCSLTNPQGHEYFQWKHLSSASAEKKLTVATSHNLKDSRVRTGPTLEIPQVSQKDVGIWECSVYGPEGRLGAVEYGLQITGAQVSGPPTIFSGQVTFGLMLTLFFLLMVCILALGLQKRARLPASFPALERIVAVTVPKEMEESQKETIQQTEC", "length": 504, "header": "tr|A0A8V0ZMF0-1|A0A8V0ZMF0_CHICK Isoform 1 of Lymphocyte activation gene 3 protein OS=Gallus gallus OX=9031 GN=LAG3 PE=3 SV=1 CANONICAL=A0A8V0ZMF0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0/entry#A0A8V0ZMF0-1", "sequence": { "sequence": "MRPVSPVLFLTLLAVNAGNILPGAAEVENRGQKVWAREGSSALLPCYLSPRKHGKSRKHLSGRTSVLWKRHGASAPQELHVVLEVEYTGLRKTALPMRPRVSVLDSALRNGNFSLCINPVRSDDVGLYEAQVAYNTEILSCQVELGVVTVTLSPPLPVVENEPLLLSCNSSHQASLVETCWFHNGRPVLISGAFCSSHGALYILRPTVSDSGSWHCQLRYADNEIISATYNLQILGFDGPTNPVVYAAAGSAADLPCTLNYLPSASGIRVVKAHWSHFAGGHLQNWSILQNQSSRNFPLHLPVVGPGDAGRYCCAVTVGNKMLSRDMTLAVITVTPRIQGPVSEGSHLLLTCSLTNPQGHEYFQWKHLSSASAEKKLTVATSHNLKDSRVRTGPTLEIPQVSQKDVGIWECSVYGPEGRLGAVEYGLQITGAQVSGPPTIFSGQVTFGLMLTLFFLLMVCILALGLQKRARLPASFPALERIVAVTVPKEMEESQKETIQQTEC", "length": 504, "header": "tr|A0A8V0ZMF0-1|A0A8V0ZMF0_CHICK Isoform 1 of Lymphocyte activation gene 3 protein OS=Gallus gallus OX=9031 GN=LAG3 PE=3 SV=1 CANONICAL=A0A8V0ZMF0-1" }, "locus": { "chromosome": "1", "start_pos": 77151108, "end_pos": 77145976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056851.1", "url": "https://www.ensembl.org/id/ENSGALT00010056851.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034564.1", "url": "https://www.ensembl.org/id/ENSGALP00010034564.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 317, "start_aa": "Thr", "end_pos": 317, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr317", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 335, "start_aa": "Thr", "end_pos": 335, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr335", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E1B7C1-1", "protein_name": "Lymphocyte activation gene 3 protein", "gene_name": "LAG3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLWEAWFQVWLFLQLLWAAAVEAPEPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLPRTRQVTWQHVPESGSAAPTPRGPGPRRYTVLRLAPGGLRIGKLPLQPRVQLEEMGLQRGDFSLWLRPARRADAGEYHAAVRFGNRALACRLRLRVGQAAVTASPPGPLWTSSWVVLNCSFSRPDLPASVHWFRGPGRVPVQESPHHHLVGNFLFLPQVSSLDSGTWGCSLTYRDGFNVSITYNLAVLGLEPRATLTVYAGAGSKVELPCRLPPGVGIQSSLTAMWTPPGEGPDLLVAGDRNNFTLRLEAVGQAQAGTYTCRVHLQGRQLSATVTLAVITVTPKPYGSSGSLRKPFCEVTPASGQERFVWSPLDKRSQRRSPGPWLLTPDARPLSQPWQCHLYQGERLLGTAVYLTELSHPGAQRSGRALGAGRTAHLPLLILGLLFLLLLVTGASSFHLWRRQWRPRRFSALEHGTHPSQASSKTGELEPELEPEPDPEVEPEPEPEPESQPQLQPEQP", "length": 516 }, "evidence": [ { "id": "A0A8V0ZMF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZMF0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SLT3-1", "protein_name": "Lymphocyte activation gene 3 protein", "gene_name": "LAG3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGEAHFLIWLLLQLLCAAAVEAPDPRAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRTGQVTWQHLPDRGPAAPSPQSPGPRRYTVLRVAPGGLRIGRPPLQPRVQLEERGLQRGDFSLWLRPARRDDAGEYRAAVSLRDRDRALVCLLRLRVGQAAVTASPPGSLWTSHWVILNCSFSRPDFPASVHWFRGPGRVPVQESPHQHLVGNFLFLSQISPLDSGTWGCIITYRDGFNVSITYNLTVLGLQPPVPLTVYAAAGATVDLPCHLPRGVGTQSSLTATWTPPGGGPDLLVAGDHGNFTLRLEAVSQAQAGTYTCRVHLQGQQLSATVTLAVITVTPKSSGLPGNPKKLLCEVTPASGQERFVWSSLDKRSWRSSPGPWLVLQEARLLSQPWQCQLYEGERLLGTAGYFTELSRPGAQRSGGALGAQKTGHLPFLILGTLLLLLLVSGAISFHVWRRRWRPRRFSALEHGTHPPQAQSKTGELEPEPELEPEPELEVEPQPEQP", "length": 507 }, "evidence": [ { "id": "A0A8V0ZMF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZMF0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P18627-1", "protein_name": "Lymphocyte activation gene 3 protein", "gene_name": "LAG3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWEAQFLGLLFLQPLWVAPVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAGVTWQHQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRVQLDERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLRASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRLEDVSQAQAGTYTCHIHLQEQQLNATVTLAIITVTPKSFGSPGSLGKLLCEVTPVSGQERFVWSSLDTPSQRSFSGPWLEAQEAQLLSQPWQCQLYQGERLLGAAVYFTELSSPGAQRSGRAPGALPAGHLLLFLILGVLSLLLLVTGAFGFHLWRRQWRPRRFSALEQGIHPPQAQSKIEELEQEPEPEPEPEPEPEPEPEPEQL", "length": 525 }, "evidence": [ { "id": "A0A8V0ZMF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZMF0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BK54-1", "protein_name": "Lymphocyte activation gene 3 protein", "gene_name": "Lag3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRQDLFLDLLLLQLLWEAPVVSSGPGKELSVVWAQEGAPVHLPCSLEFPHLDPNFLRRGWVTWQHRPDSDQPASIPALDLLQGMPSTRRHPPHRYTVLSVAPGGLRSGRQPLLSHVQLEKRGPQRGDFSLWLRPATRKDAGEYHAFVRLPDRDFSCSLRLRVGQASMIASPPGTLKPSDWVILNCSFSRPDRPVSVHWFQGQSRVPVHNSPRHYLAESFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVQGLEPVAPLTVYAAEGSRVELPCHLPPVVGTPSLLIAKWTPPGGGPELPVTGKSGNFTLQLENVGRAQAGTYTCSIHLQGRQLSAAVTLAVITVTPKSFGLPGSPQKLLCEVVPASGEGRFVWRPLSDLSRSSLGPVLELQEAKLLAEQWQCQLYEGQKLLGATVYTAESSSGAWSAKRISGDLKGGHLFLSLILGALALFLLVTGAFGFHLWRRQLLRRRFSALEHGIRPPPVQSKIEELEREPETEMEPETEPDPEPQPEPELEPESRQL", "length": 525 }, "evidence": [ { "id": "A0A8V0ZMF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZMF0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61790-1", "protein_name": "Lymphocyte activation gene 3 protein", "gene_name": "Lag3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MREDLLLGFLLLGLLWEAPVVSSGPGKELPVVWAQEGAPVHLPCSLKSPNLDPNFLRRGGVIWQHQPDSGQPTPIPALDLHQGMPSPRQPAPGRYTVLSVAPGGLRSGRQPLHPHVQLEERGLQRGDFSLWLRPALRTDAGEYHATVRLPNRALSCSLRLRVGQASMIASPSGVLKLSDWVLLNCSFSRPDRPVSVHWFQGQNRVPVYNSPRHFLAETFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVLGLEPVAPLTVYAAEGSRVELPCHLPPGVGTPSLLIAKWTPPGGGPELPVAGKSGNFTLHLEAVGLAQAGTYTCSIHLQGQQLNATVTLAVITVTPKSFGLPGSRGKLLCEVTPASGKERFVWRPLNNLSRSCPGPVLEIQEARLLAERWQCQLYEGQRLLGATVYAAESSSGAHSARRISGDLKGGHLVLVLILGALSLFLLVAGAFGFHWWRKQLLLRRFSALEHGIQPFPAQRKIEELERELETEMGQEPEPEPEPQLEPEPRQL", "length": 521 }, "evidence": [ { "id": "A0A8V0ZMF0", "url": "https://omabrowser.org/oma/group/A0A8V0ZMF0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0" } ], "pmid": "" }, { "name": "MHC class II protein binding", "id": "GO:0042289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 140, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 317, 335 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 291, "end_pos": 293 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMF8-1", "uniprot_ac": "A0A8V0ZMF8", "uniprot_id": "A0A8V0ZMF8_CHICK", "mass": { "chemical_mass": 51376.0, "monoisotopic_mass": 51376.0 }, "refseq": { "ac": "XP_015134585", "name": "SH2 domain-containing adapter protein F isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134585" }, "gene_names": [ { "name": "SHF", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8" } ] }, { "name": "SHF", "type": "synonym", "evidence": [ { "id": "XP_015134585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134585" } ] } ], "protein_names": [ { "name": "SH2 domain-containing adapter protein F isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015134585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134585" } ] }, { "name": "Src homology 2 domain containing F", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134585" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SHF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8", "locus": { "chromosome": "10", "start_pos": 882320, "end_pos": 900423, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022236", "url": "https://www.ensembl.org/id/ENSGALG00010022236" } ] } } ], "crossref": [ { "id": "A0A8V0ZMF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10392", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10392", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415339", "url": "https://www.ncbi.nlm.nih.gov/gene/415339", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415339", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415339", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKPDYRQ", "url": "https://omabrowser.org/oma/group/PKPDYRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMF8", "url": "https://www.orthodb.org/?gene=A0A8V0ZMF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP88", "url": "https://www.orthodb.org/?gene=A0A8V0ZP88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUX1", "url": "https://www.orthodb.org/?gene=A0A8V0ZUX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15127:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15127:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015134585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134585", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP88", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLNGAAAGSERGGGAGAGAGAGAGGGAPQCVGTMARWLREHLGFRSAKPAPPAPPKPDYRAGPPQPPPPPGGAAEPLASAQPDIVAAYRLQKERDFEDPYSGAPPPAAPDGPRYVSPKHRLIKVEAAEKSPAGPAPPPAAPGSPPAGPEPPDEPPQELAVLEDYADPFDAAQVAGSQAGVEKVAENDGYMEPYEAQKMMAEIRQKGLREAPSRPLHLYDTPYEPVSGGLDVDTDCPACPRPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVEIKVIKDLPWPPPVGQLNSGETPPDGEASASVPPQHGPQSYEDANGPSEGLGYGRTSPCREEKARTALRHGTSSLKSTKTLSVEPGPFLGERIDPALPLESQCWYHGAISRTDAETLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTQENKYVLGQHSPPFDSVPEIIHHYASRKLPIKGAEHMSLLYPVAIRTL", "length": 479, "header": "tr|A0A8V0ZMF8-1|A0A8V0ZMF8_CHICK Isoform 1 of Src homology 2 domain containing F OS=Gallus gallus OX=9031 GN=SHF PE=4 SV=1 CANONICAL=A0A8V0ZMF8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8/entry#A0A8V0ZMF8-1", "sequence": { "sequence": "MLLNGAAAGSERGGGAGAGAGAGAGGGAPQCVGTMARWLREHLGFRSAKPAPPAPPKPDYRAGPPQPPPPPGGAAEPLASAQPDIVAAYRLQKERDFEDPYSGAPPPAAPDGPRYVSPKHRLIKVEAAEKSPAGPAPPPAAPGSPPAGPEPPDEPPQELAVLEDYADPFDAAQVAGSQAGVEKVAENDGYMEPYEAQKMMAEIRQKGLREAPSRPLHLYDTPYEPVSGGLDVDTDCPACPRPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVEIKVIKDLPWPPPVGQLNSGETPPDGEASASVPPQHGPQSYEDANGPSEGLGYGRTSPCREEKARTALRHGTSSLKSTKTLSVEPGPFLGERIDPALPLESQCWYHGAISRTDAETLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTQENKYVLGQHSPPFDSVPEIIHHYASRKLPIKGAEHMSLLYPVAIRTL", "length": 479, "header": "tr|A0A8V0ZMF8-1|A0A8V0ZMF8_CHICK Isoform 1 of Src homology 2 domain containing F OS=Gallus gallus OX=9031 GN=SHF PE=4 SV=1 CANONICAL=A0A8V0ZMF8-1" }, "locus": { "chromosome": "10", "start_pos": 898884, "end_pos": 886205, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054100.1", "url": "https://www.ensembl.org/id/ENSGALT00010054100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032631.1", "url": "https://www.ensembl.org/id/ENSGALP00010032631.1" } ] } }, { "isoform_ac": "A0A8V0ZP88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8/entry#A0A8V0ZP88-1", "sequence": { "sequence": "MLLNGAAAGSERGGGAGAGAGAGAGGGAPQCVGTMARWLREHLGFRSAKPAPPAPPKPDYRAGPPQPPPPPGGAAEPLASAQPDIVAAYRLQKERDFEDPYSGAPPPAAPDGPRYVSPKHRLIKVEAAEKSPAGPAPPPAAPGSPPAGPEPPDEPPQELAVLEDYADPFDAAQVAGSQAGVEKVAENDGYMEPYEAQKMMAEIRQKGLREAPSRPLHLYDTPYEPVSGGLDVDTDCPACPRPRESRLPEDDERPPEEYDQPWEWKKERISKAFAGPSEGLGYGRTSPCREEKARTALRHGTSSLKSTKTLSVEPGPFLGERIDPALPLESQCWYHGAISRTDAETLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTQENKYVLGQHSPPFDSVPEIIHHYASRKLPIKGAEHMSLLYPVAIRTL", "length": 433, "header": "tr|A0A8V0ZP88-1|A0A8V0ZP88_CHICK Computationally mapped isoform of Src homology 2 domain containing F OS=Gallus gallus OX=9031 GN=SHF PE=4 SV=1 CANONICAL=A0A8V0ZMF8-1" }, "locus": { "chromosome": "10", "start_pos": 898884, "end_pos": 886205, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054102.1", "url": "https://www.ensembl.org/id/ENSGALT00010054102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032633.1", "url": "https://www.ensembl.org/id/ENSGALP00010032633.1" } ] } }, { "isoform_ac": "A0A8V0ZUX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8/entry#A0A8V0ZUX1-1", "sequence": { "sequence": "MELSFGSANAEICSCFLEPETHRQEWRDVACVLSRLQKKYECAEPCGVQSSERPSDLSQHRGVSRGAPTQLCPPHPAHRAAVELLWAHPLRRGSQHCSKLKAQLAVLEDYADPFDAAQVAGSQAGVEKVAENDGYMEPYEAQKMMAEIRQKGLREAPSRPLHLYDTPYEPVSGGLDVDTDCPACPRPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVEIKVIKDLPWPPPVGQLNSGETPPDGEASASVPPQHGPQSYEDANGPSEGLGYGRTSPCREEKARTALRHGTSSLKSTKTLSVEPGPFLGERIDPALPLESQCWYHGAISRTDAETLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTQENKYVLGQHSPPFDSVPEIIHHYASRKLPIKGAEHMSLLYPVAIRTL", "length": 424, "header": "tr|A0A8V0ZUX1-1|A0A8V0ZMF8_CHICK Computationally mapped isoform of Src homology 2 domain containing F OS=Gallus gallus OX=9031 GN=SHF PE=4 SV=1 CANONICAL=A0A8V0ZMF8-1" }, "locus": { "chromosome": "10", "start_pos": 900224, "end_pos": 886205, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054104.1", "url": "https://www.ensembl.org/id/ENSGALT00010054104.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032635.1", "url": "https://www.ensembl.org/id/ENSGALP00010032635.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415339", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415339", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q7M4L6-1", "protein_name": "SH2 domain-containing adapter protein F", "gene_name": "SHF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQEGGPVRSAPCRTGTLEGSRQGSPGHRKRASPKGSLSSAQPHSWMLTPSPLNSHCAHREPISSSPQPVANGPKQKKKSNWRSTTRLRIIRLRDRLEPRPLAILEDYADPFDVQETGEGSAGASGAPEKVPENDGYMEPYEAQKMMAEIRGSKETATQPLPLYDTPYEPEEDGATAEGEGAPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAVDIKVIKDLPWPPPVGQLDSSPSLPDGDRDISGPASPLPEPSLEDSSAQFEGPEKSCLSPGREEKGRLPPRLSAGNPKSAKPLSMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRTL", "length": 423 }, "evidence": [ { "id": "A0A8V0ZMF8", "url": "https://omabrowser.org/oma/group/A0A8V0ZMF8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMF8" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 379, "end_pos": 474, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMG3-1", "uniprot_ac": "A0A8V0ZMG3", "uniprot_id": "A0A8V0ZMG3_CHICK", "mass": { "chemical_mass": 38556.0, "monoisotopic_mass": 38556.0 }, "refseq": { "ac": "XP_015143781", "name": "catechol O-methyltransferase domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143781" }, "gene_names": [ { "name": "COMTD1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG3" } ] }, { "name": "COMTD1", "type": "synonym", "evidence": [ { "id": "XP_015143781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143781" } ] } ], "protein_names": [ { "name": "Catechol-O-methyltransferase domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG3/entry#names_and_taxonomy" } ] }, { "name": "catechol O-methyltransferase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_015143781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143781" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_015143781.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143781" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COMTD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG3", "locus": { "chromosome": "6", "start_pos": 15610889, "end_pos": 15602819, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022238", "url": "https://www.ensembl.org/id/ENSGALG00010022238" } ] } } ], "crossref": [ { "id": "A0A8V0ZMG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423730", "url": "https://www.ncbi.nlm.nih.gov/gene/423730", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423730", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423730", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWHERET", "url": "https://omabrowser.org/oma/group/TWHERET/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMG3", "url": "https://www.orthodb.org/?gene=A0A8V0ZMG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10509", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10509", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10509:SF93", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10509:SF93", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01596", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01596", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015143781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143781", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTESRAQPLLHRYPIRHTFPSREDAASLNLSLSRRTWHERETETTVRPGGGGPGPPRTTRRTAPPHLAPPWPHRTVPLAVASPRPEMPLFSVPKEVAVGTAMLGVAFATGLLAGKRYPSLLFGTSKPHKSIIGKSSPLWQYILDHSLREHPILKKLRLLTAEYPWGKMMVSCDQAQLMANLIKLIKAKKVIEVGVLTGYNALSMALALPDNGRVIACDINEDYAKIGKPLWKEAGVDHKIDLRIKPATQTLDELLAGGEAETFDFAFIDADKESYNEYYEKCLRLIKKGGIIAIDNVLRCGMVLKPRKDDLATQSIHHLNEKLVRDARVNISMIPMGDGVTLVFKL", "length": 347, "header": "tr|A0A8V0ZMG3-1|A0A8V0ZMG3_CHICK Isoform 1 of Catechol-O-methyltransferase domain containing 1 OS=Gallus gallus OX=9031 GN=COMTD1 PE=3 SV=1 CANONICAL=A0A8V0ZMG3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG3/entry#A0A8V0ZMG3-1", "sequence": { "sequence": 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"A0A8V0ZMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 }, { "start_pos": 331, "end_pos": 333 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMH5-1", "uniprot_ac": "A0A8V0ZMH5", "uniprot_id": "A0A8V0ZMH5_CHICK", 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], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134584.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134584" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC28A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZMH5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMH5", "database": "AlphaFoldDB", "categories": [] }, { "id": "415338", "url": "https://www.ncbi.nlm.nih.gov/gene/415338", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415338", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415338", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVWHTVI", "url": "https://omabrowser.org/oma/group/IVWHTVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMH5", "url": "https://www.orthodb.org/?gene=A0A8V0ZMH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPT4", "url": "https://www.orthodb.org/?gene=A0A8V0ZPT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10590:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10590:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-83936", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-83936", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9748787", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9748787", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9755088", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755088", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015134584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134584", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLEMEGNQITLDSLEKGIDNPAFSSLGEEELCEERGGPRGGNEKRREGNGRVALYCRKALRPASKAKRFCKAHAKALRRVFWGLLGAAYLCYFIAACWLNFQRALALVVITAVVIFFVCWSLFKKYCGAKVLTLLSPLWKCLQKSWPWLKWLLYVLLLGGLVTWLALDTAKNPEQLISLAGFCVLVLFLFAFSKHHSAVSWRAVFWGLGLEFLIGLFILRTTPGIQAFQWLGDQIQVFLGYTKAGSGFVFGNTLIEDVFAFQSLPIIVFFSCVMSILYYLGVMQWLILKISWLLQVSLGTTPTETLSVAGNIFVGQTEAPLLIRPYLADMTHSEIHAVMAGGFSTIAGSVMGAYISFGIDAASLIAASVMAAPCALAMSKLVYPEVEESKFKGKESVRIASGEERNILEAASNGAAASVGLVANIAANLIAFLAVLEFINAALRWFGEMVEIENLSFEMICSYVLMPVAFLMGADWADSPLVAELLGIKIFLNEFVAYQQLATYKKNRLSGLEEWSEGRKQWISERAESITTFALCGFANLSSIGIMLGGLTSMVPQRKSELASIVLRALLTGICVSMLNSCLAGLLYVPTEMGNCVTILSTANFTSTNYAIYTCCKQLFASTVLENGTLSFTGAWASVAESVPCLTQCCGYYNHTSCTV", "length": 662, "header": "tr|A0A8V0ZMH5-1|A0A8V0ZMH5_CHICK Isoform 1 of Sodium/nucleoside cotransporter OS=Gallus gallus OX=9031 GN=SLC28A2 PE=3 SV=1 CANONICAL=A0A8V0ZMH5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5/entry#A0A8V0ZMH5-1", "sequence": { "sequence": "MARLEMEGNQITLDSLEKGIDNPAFSSLGEEELCEERGGPRGGNEKRREGNGRVALYCRKALRPASKAKRFCKAHAKALRRVFWGLLGAAYLCYFIAACWLNFQRALALVVITAVVIFFVCWSLFKKYCGAKVLTLLSPLWKCLQKSWPWLKWLLYVLLLGGLVTWLALDTAKNPEQLISLAGFCVLVLFLFAFSKHHSAVSWRAVFWGLGLEFLIGLFILRTTPGIQAFQWLGDQIQVFLGYTKAGSGFVFGNTLIEDVFAFQSLPIIVFFSCVMSILYYLGVMQWLILKISWLLQVSLGTTPTETLSVAGNIFVGQTEAPLLIRPYLADMTHSEIHAVMAGGFSTIAGSVMGAYISFGIDAASLIAASVMAAPCALAMSKLVYPEVEESKFKGKESVRIASGEERNILEAASNGAAASVGLVANIAANLIAFLAVLEFINAALRWFGEMVEIENLSFEMICSYVLMPVAFLMGADWADSPLVAELLGIKIFLNEFVAYQQLATYKKNRLSGLEEWSEGRKQWISERAESITTFALCGFANLSSIGIMLGGLTSMVPQRKSELASIVLRALLTGICVSMLNSCLAGLLYVPTEMGNCVTILSTANFTSTNYAIYTCCKQLFASTVLENGTLSFTGAWASVAESVPCLTQCCGYYNHTSCTV", "length": 662, "header": "tr|A0A8V0ZMH5-1|A0A8V0ZMH5_CHICK Isoform 1 of Sodium/nucleoside cotransporter OS=Gallus gallus OX=9031 GN=SLC28A2 PE=3 SV=1 CANONICAL=A0A8V0ZMH5-1" }, "locus": { "chromosome": "10", "start_pos": 915929, "end_pos": 909313, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054121.1", "url": "https://www.ensembl.org/id/ENSGALT00010054121.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032652.1", "url": "https://www.ensembl.org/id/ENSGALP00010032652.1" } ] } }, { "isoform_ac": "A0A8V0ZPT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5/entry#A0A8V0ZPT4-1", "sequence": { "sequence": "MARLEMEGNQITLDSLEKGIDNPAFSSLGEEELCEERGGPRGGNEKRREGNGRVALYCRKALRPASKAKRFCKAHAKALRRVFWGLLGAAYLCYFIAACWLNFQRALALVVITAVVIFFVCWSLFKKYCGAKVLTLLSPLWKCLQKSWPWLKWLLYVLLLGGLVTWLALDTAKNPEQLISLAGFCVLVLFLFAFSKHHSAVSWRAVFWGLGLEFLIGLFILRTTPGIQAFQWLGDQIQVFLGYTKAGSGFVFGNTLIEDVFAFQISWLLQVSLGTTPTETLSVAGNIFVGQTEAPLLIRPYLADMTHSEIHAVMAGGFSTIAGSVMGAYISFGIDAASLIAASVMAAPCALAMSKLVYPEVEESKFKGKESVRIASGEERNILEAASNGAAASVGLVANIAANLIAFLAVLEFINAALRWFGEMVEIENLSFEMICSYVLMPVAFLMGADWADSPLVAELLGIKIFLNEFVAYQQLATYKKNRLSGLEEWSEGRKQWISERAESITTFALCGFANLSSIGIMLGGLTSMVPQRKSELASIVLRALLTGICVSMLNSCLAGLLYVPTEMGNCVTILSTANFTSTNYAIYTCCKQLFASTVLENGTLSFTGAWASVAESVPCLTQCCGYYNHTSCTV", "length": 635, "header": "tr|A0A8V0ZPT4-1|A0A8V0ZPT4_CHICK Computationally mapped isoform of Solute carrier family 28 member 2 OS=Gallus gallus OX=9031 GN=SLC28A2 PE=3 SV=1 CANONICAL=A0A8V0ZMH5-1" }, "locus": { "chromosome": "10", "start_pos": 915929, "end_pos": 909313, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054127.1", "url": "https://www.ensembl.org/id/ENSGALT00010054127.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032658.1", "url": "https://www.ensembl.org/id/ENSGALP00010032658.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415338", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415338", "resource": "KEGG Pathway" }, { "id": "R-GGA-83936", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-83936", "resource": "Reactome", "description": "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" }, { "id": "R-GGA-9748787", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9748787", "resource": "Reactome", "description": "Azathioprine ADME" }, { "id": "R-GGA-9755088", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9755088", "resource": "Reactome", "description": "Ribavirin ADME" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZNF3-1", "protein_name": "Sodium/nucleoside cotransporter", "gene_name": "SLC28A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDNTPRQRDPISLTSVANGLENMGAELLESLEEGRTPGSDSSPAEVGGSWSKAGPEHLGRRSLQPALRVRRFCREHTQLFRWICTGLLCTAFAAFLLIACLLDFQRALALFVLFCVVLFFLAHSLLKRLLGPKLLRCVKPLRHPCLNLWFKRGLALAAFLGLVLWLVLDTAQRPEQLVSFGGICVFILLLFAGSKHHRAVSWRAVSWGLGLQFALGLFVIRTEPGFIAFQWLGDQIQIFLSYTEAGSSFVFGEALVKDVFAFQVLPIIVFFSCAMSVLYYVGLMQWVILKISWLMQATMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEIHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFKREEGVKLTYGDAQNLLEAASSGAAMSVRVVTNIAANLIAFLAVLAFINAALSWLGDMVDVQGLSFQLICSYVLRPVAFLMGVAWEDCPVVAELLGMKLFLNEFVAYQELSGYKQRRLAGAEEWVGSRKQWISVRAEILTTYALCGFANFSSIGIMLGGLTSMVPQRKGDFSQIVLRALCTGACVSLVNACVAGILYVPRGAEVDCVSFLNTTLSSSSFEVYQCCRQFFQSTSLEFSPEALDNCCRFYNHTICVQ", "length": 648 }, "evidence": [ { "id": "A0A8V0ZMH5", "url": "https://omabrowser.org/oma/group/A0A8V0ZMH5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1LFZ9-1", "protein_name": "Sodium/nucleoside cotransporter", "gene_name": "SLC28A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEDNTPRGRESISLTSVAIGLDNRGADLLESLEEGRDPAGNSSPSEVGDSWSKAGPEPFSGWRRRLQPALRVRHFCREHAQLFRWICIGLLCTAYTAFLLAACILNFQRALALFVLTCVVLVFLAHSLLKRLLGPKLLRCVKPLGHPCLKLWFKRGLALAAFLGLVLWLALDTSQRPEQLVSFGGICVFVGFLFAVSKHHRAVSWRAVFWGLGLQFVLGLVVIRTEPGFIAFQWLGDQIQIFLSYTESGSSFVFGEALVKDVFAFQVLPIIVFFSCAMSVLYYVGLMQWVIMKISWLMQITMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEIHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFRSEEGVKLTYGDAQNLLEAASSGAALSVKVVTNIAANLIAFLAVLDFINAALSWLGNMVDIQGLSFQLICSYILRPVAFLMGVAWEDCSVVAELLGMKLFLNEFVAYQGLSEYKQRRLAGTEEWVGSKKQWISVRAEILTTFALCGFANFSSIGIMLGGLTSMAPQRKSDFSQIVLRALCTGACVSLVNACVAGILYMPRGPAVDCVSLLNTTLNSSSFEVYQCCHQAFQSTGPEFSLEALDNCCRFYNHTICA", "length": 649 }, "evidence": [ { "id": "A0A8V0ZMH5", "url": "https://omabrowser.org/oma/group/A0A8V0ZMH5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9PXX9-1", "protein_name": "Sodium/nucleoside cotransporter 1", "gene_name": "Slc28a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADDTPRQRESISLTPVAHGLENMGAEFLEIMEEGQLPHRHSSLPEGGGSRSKAVWKPFSRWRSLQPTVQARSLCREHWQLFEWISKGLLSTAYIGFLIVACLLDFPRALALFVITCVVLVFLAYNLLKRLLGSKLKKCVKFQGHSCLSLWLKRGLALAAGLGVILWLSLDTAQRPEQLVSFAGICVFLVLLFAGSKHHRAVSWRAVSWGLGLQFVLGLFVIRTEPGFVAFQWLGDQIRVFLSYTEAGSSFVFGEALVKDVFAFQVLPIIVFFSCVMSVLYYLGLMQWVILKIAWLMQVTMGTSATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDASSLIAASVMAAPCALALSKLVYPEVEESKFRSEEGVKLTYGDAQNLVEAASAGAAISVKVVANIAANLIAFLAVLAFINAALSWLGDMVDIQGLSFQLICSYVLRPVAFLMGVAWEDCPVVAELLGIKLFLNEFVAYQELSQYKQRRLAGAEEWLGDKKQWISVRAEILTTYALCGFANFSSIGIMLGGLTSMVPQRRSDFSQIVLRALITGAFVSLVNACVAGILYVPRGVEVDCMSLLNQTVSSSSFEVYLCCRQVFQNTSLEFGQEALHNCCRFYNHTVCT", "length": 648 }, "evidence": [ { "id": "A0A8V0ZMH5", "url": "https://omabrowser.org/oma/group/A0A8V0ZMH5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O00337-1", "protein_name": "Sodium/nucleoside cotransporter 1", "gene_name": "SLC28A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENDPSRRRESISLTPVAKGLENMGADFLESLEEGQLPRSDLSPAEIRSSWSEAAPKPFSRWRNLQPALRARSFCREHMQLFRWIGTGLLCTGLSAFLLVACLLDFQRALALFVLTCVVLTFLGHRLLKRLLGPKLRRFLKPQGHPRLLLWFKRGLALAAFLGLVLWLSLDTSQRPEQLVSFAGICVFVALLFACSKHHCAVSWRAVSWGLGLQFVLGLLVIRTEPGFIAFEWLGEQIRIFLSYTKAGSSFVFGEALVKDVFAFQVLPIIVFFSCVISVLYHVGLMQWVILKIAWLMQVTMGTTATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDATSLIAASVMAAPCALALSKLVYPEVEESKFRREEGVKLTYGDAQNLIEAASTGAAISVKVVANIAANLIAFLAVLDFINAALSWLGDMVDIQGLSFQLICSYILRPVAFLMGVAWEDCPVVAELLGIKLFLNEFVAYQDLSKYKQRRLAGAEEWVGDRKQWISVRAEVLTTFALCGFANFSSIGIMLGGLTSMVPQRKSDFSQIVLRALFTGACVSLVNACMAGILYMPRGAEVDCMSLLNTTLSSSSFEIYQCCREAFQSVNPEFSPEALDNCCRFYNHTICAQ", "length": 649 }, "evidence": [ { "id": "A0A8V0ZMH5", "url": "https://omabrowser.org/oma/group/A0A8V0ZMH5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62674-1", "protein_name": "Sodium/nucleoside cotransporter 1", "gene_name": "Slc28a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADNTQRQRESISLTPMAHGLENMGAEFLESMEEGRLPHSHSSLPEGEGGLNKAERKAFSRWRSLQPTVQARSFCREHRQLFGWICKGLLSTACLGFLMVACLLDLQRALALLIITCVVLVFLAYDLLKRLLGSKLRRCVKFQGHSCLSLWLKRGLALAAGVGLILWLSLDTAQRPEQLVSFAGICVFLVLLFAGSKHHRAVSWRAVSWGLGLQFVLGLFVIRTEPGFIAFQWLGDQIQVFLSYTEAGSSFVFGEALVKDVFAFQVLPIIIFFSCVMSVLYYLGLMQWVILKIAWLMQVTMGTSATETLSVAGNIFVSQTEAPLLIRPYLADMTLSEVHVVMTGGYATIAGSLLGAYISFGIDAASLIAASVMAAPCALALSKLVYPEVEESKFRSENGVKLTYGDAQNLLEAASAGAAISVKVVANIAANLIAFLAVLAFVNAALSWLGDMVDIQGLSFQLICSYVLRPVAFLMGVAWEDCPVVAELLGIKFFLNEFVAYQELSQYKQRRLAGAEEWLGDKKQWISVRAEILTTYALCGFANFSSIGIMLGGLTSLVPQRRSDFSQIVLRALITGAFVSLLNACVAGILYVPRGVEVDCVSLLNQTVSSSSFEVYLCCRQVFQSTSSEFSQVALDNCCRFYNHTVCT", "length": 648 }, "evidence": [ { "id": "A0A8V0ZMH5", "url": "https://omabrowser.org/oma/group/A0A8V0ZMH5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleoside:sodium symporter activity", "id": "GO:0005415", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005415", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5" } ], "pmid": "" }, { "name": "nucleoside transmembrane transporter activity", "id": "GO:0005337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005337", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleoside transmembrane transport", "id": "GO:1901642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901642", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5" }, { "id": "PF07662", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07662" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Concentrative nucleoside transporter C-terminal", "eco_id": "ECO_0000259", "start_pos": 366, "end_pos": 587, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZMH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5" }, { "id": "PF01773", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01773" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Concentrative nucleoside transporter N-terminal", "eco_id": "ECO_0000259", "start_pos": 182, "end_pos": 254, "start_aa": "Ala", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZMH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH5" }, { "id": "PF07670", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07670" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoside transporter/FeoB GTPase Gate", "eco_id": "ECO_0000259", "start_pos": 263, "end_pos": 360, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 456, "end_pos": 458 }, { "start_pos": 542, "end_pos": 544 }, { "start_pos": 606, "end_pos": 608 }, { "start_pos": 629, "end_pos": 631 }, { "start_pos": 656, "end_pos": 658 } ] }, "class_list": [], 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMH6-1", "uniprot_ac": "A0A8V0ZMH6", "uniprot_id": "A0A8V0ZMH6_CHICK", "mass": { "chemical_mass": 55040.0, "monoisotopic_mass": 55040.0 }, "refseq": {}, "gene_names": [ { "name": "CD4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6" } ] } ], "protein_names": [ { "name": "CD4 molecule", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus 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"https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11422", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11422:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11422:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZMH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSQ6", "url": 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"MERCGAVVSCVFAVILVLQLGLTPIMAQQEQQIGIAGKEVILSCKAINNQKDGTCTWKYKYKEVSSTIISFSKAQVFKGKAPMTHRSELNSNSKKLKVSDLSLDDAGIYTCACYSPVVSISLHVFKLTISSNGHFLTNEDLELTLMQNSSHSQPHLSIKLFNINNNIVTTEILQEEAPQKYILKLKQLKAIDSGTWMCHVYSNSPSINQNISFDVKVLGFEEERLEIVYTTVGNTAILSWHLNFRKIKWKEGFTGKLNWEPQGNTAIHELLNFSVTTHQELHKTKKSNHIWFEISEGKTDGTMDVKIPKVQLNHSGQYKCQLEINGRRTESVRALVVMQVTAIPAGPLSRGGKMTLLCQVSGPLPSNAHLLWERVNGTQMEMKKSKQHEAKVEVNVSAPGLWNCHLVEDNNKKISLNYTVEEAHVWNSYAVIGIIIGASVLVIGLACMCIITGMRWQRRRVSIPVSVKETGKKDGTSKTILAGKEDMSVSTPDV", "length": 494, "header": "tr|A0A8V0ZMH6-1|A0A8V0ZMH6_CHICK Isoform 1 of CD4 molecule OS=Gallus gallus OX=9031 GN=CD4 PE=4 SV=1 CANONICAL=A0A8V0ZMH6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6/entry#A0A8V0ZMH6-1", "sequence": { "sequence": "MERCGAVVSCVFAVILVLQLGLTPIMAQQEQQIGIAGKEVILSCKAINNQKDGTCTWKYKYKEVSSTIISFSKAQVFKGKAPMTHRSELNSNSKKLKVSDLSLDDAGIYTCACYSPVVSISLHVFKLTISSNGHFLTNEDLELTLMQNSSHSQPHLSIKLFNINNNIVTTEILQEEAPQKYILKLKQLKAIDSGTWMCHVYSNSPSINQNISFDVKVLGFEEERLEIVYTTVGNTAILSWHLNFRKIKWKEGFTGKLNWEPQGNTAIHELLNFSVTTHQELHKTKKSNHIWFEISEGKTDGTMDVKIPKVQLNHSGQYKCQLEINGRRTESVRALVVMQVTAIPAGPLSRGGKMTLLCQVSGPLPSNAHLLWERVNGTQMEMKKSKQHEAKVEVNVSAPGLWNCHLVEDNNKKISLNYTVEEAHVWNSYAVIGIIIGASVLVIGLACMCIITGMRWQRRRVSIPVSVKETGKKDGTSKTILAGKEDMSVSTPDV", "length": 494, "header": "tr|A0A8V0ZMH6-1|A0A8V0ZMH6_CHICK Isoform 1 of CD4 molecule OS=Gallus gallus OX=9031 GN=CD4 PE=4 SV=1 CANONICAL=A0A8V0ZMH6-1" }, "locus": { "chromosome": "1", "start_pos": 77168504, "end_pos": 77163169, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056881.1", "url": "https://www.ensembl.org/id/ENSGALT00010056881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034589.1", "url": "https://www.ensembl.org/id/ENSGALP00010034589.1" } ] } }, { "isoform_ac": "A0A8V0ZSQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6/entry#A0A8V0ZSQ6-1", "sequence": { "sequence": "MERCGAVVSCVFAVILVLQLGLTPIMAQQEQQIGIAGKEVILSCKAINNQKDGTCTWKYKYKEVSSTIISFSKAQVFKVTISSNGHFLTNEDLELTLMQNSSHSQPHLSIKLFNINNNIVTTEILQEEAPQKYILKLKQLKAIDSGTWMCHVYSNSPSINQNISFDVKVLGFEEERLEIVYTTVGNTAILSWHLNFRKIKWKEGFTGKLNWEPQGNTAIHELLNFSVTTHQELHKTKKSNHIWFEISEGKTDGTMDVKIPKVQLNHSGQYKCQLEINGRRTESVRALVVMQVTAIPAGPLSRGGKMTLLCQVSGPLPSNAHLLWERVNGTQMEMKKSKQHEAKVEVNVSAPGLWNCHLVEDNNKKISLNYTVEEAHVWNSYAVIGIIIGASVLVIGLACMCIITGMRWQRRRKRARRMAQAKQYLLEKKTCQCQRRMYK", "length": 439, "header": "tr|A0A8V0ZSQ6-1|A0A8V0ZMH6_CHICK Computationally mapped isoform of CD4 molecule OS=Gallus gallus OX=9031 GN=CD4 PE=4 SV=1 CANONICAL=A0A8V0ZMH6-1" }, "locus": { "chromosome": "1", "start_pos": 77168508, "end_pos": 77163169, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056878.1", "url": "https://www.ensembl.org/id/ENSGALT00010056878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034586.1", "url": "https://www.ensembl.org/id/ENSGALP00010034586.1" } ] } }, { "isoform_ac": "A0A8V0ZVZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6/entry#A0A8V0ZVZ2-1", "sequence": { "sequence": "MERCGAVVSCVFAVILVLQLGLTPIMAQQEQQIGIAGKEVILSCKAINNQKDGTCTWKYKYKEVSSTIISFSKAQVFKGKAPMTHRSELNSNSKKLKVSDLSLDDAGIYTCACYSPVVSISLHVFKLTISSNGHFLTNEDLELTLMQNSSHSQPHLSIKLFNINNNIVTTEILQEEAPQKYILKLKQLKAIDSGTWMCHVYSNSPSINQNISFDVKVLGFEEERLEIVYTTVGNTAILSWHLNFRKIKWKEGFTGKLNWEPQGNTAIHELLNFSVTTHQELHKTKKSNHIWFEISEGKTDGTMDVKIPKVQLNHSGQYKCQLEINGRRTESVRALVVMQVTAIPAGPLSRGGKMTLLCQVSGPLPSNAHLLWERVNGTQMEMKKSKQHEAKVEVNVSAPGLWNCHLVEDNNKKISLNYTVEEAHVWNSYAVIGIIIGASVLVIGLACMCIITGMRWQRRRKRARRMAQAKQYLLEKKTCQCQRLQQYK", "length": 488, "header": "tr|A0A8V0ZVZ2-1|A0A8V0ZMH6_CHICK Computationally mapped isoform of CD4 molecule OS=Gallus gallus OX=9031 GN=CD4 PE=4 SV=1 CANONICAL=A0A8V0ZMH6-1" }, "locus": { "chromosome": "1", "start_pos": 77167970, "end_pos": 77163169, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056874.1", "url": "https://www.ensembl.org/id/ENSGALT00010056874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034582.1", "url": "https://www.ensembl.org/id/ENSGALP00010034582.1" } ] } }, { "isoform_ac": "A0A8V0ZVZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6/entry#A0A8V0ZVZ8-1", "sequence": { "sequence": "MERCGAVVSCVFAVILVLQLGLTPIMAQQEQQIGIAGKEVILSCKAINNQKDGTCTWKYKYKEVSSTIISFSKAQVFKGKAPMTHRSELNSNSKKLKVSDLSLDDAGIYTCACYSPVVSISLHVFKLTISSNGHFLTNEDLELTLMQNSSHSQPHLSIKLFNINNNIVTTEILQEEAPQKYILKLKQLKAIDSGTWMCHVYSNSPSINQNISFDVKVLGFEEERLEIVYTTVGNTAILSWHLNFRKIKWKEGFTGKLNWEPQGNTAIHELLNFSVTTHQELHKTKKSNHIWFEISEGKTDGTMDVKIPKVQLNHSGQYKCQLEINGRRTESVRALVVMQVTAIPAGPLSRGGKMTLLCQVSGPLPSNAHLLWERVNGTQMEMKKSKQHEAKVEVNVSAPGLWNCHLVEDNNKKISLNYTVETGKKDGTSKTILAGKEDMSVSTPDV", "length": 446, "header": "tr|A0A8V0ZVZ8-1|A0A8V0ZMH6_CHICK Computationally mapped isoform of CD4 molecule OS=Gallus gallus OX=9031 GN=CD4 PE=4 SV=1 CANONICAL=A0A8V0ZMH6-1" }, "locus": { "chromosome": "1", "start_pos": 77168504, "end_pos": 77163169, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056879.1", "url": "https://www.ensembl.org/id/ENSGALT00010056879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034587.1", "url": "https://www.ensembl.org/id/ENSGALP00010034587.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6" } ], "pmid": "" }, { "name": "MHC class II protein complex binding", "id": "GO:0023026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023026", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6" } ], "pmid": "" }, { "name": "virus receptor activity", "id": "GO:0001618", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001618", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMH6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMH6", "url": 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"MAARWSSENVVVEFRDAQATAMSVDCLGQHAVLSGRRFLYIVNLDAPNEGHRKISRQSKWDIGAVQWNPHDSYAYYFAASSNQRVDLYKWKEGNGEVCTSLQGHTRVISDLDWSVFEPDLLVTSSVDTYIYIWDIKDTRKPTVSLSAVAGASQVKWNKKNANCLATSHDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDNEYTLATSSQDNSVRFWDYRQPRKYLNILPCQVPVWKARYTPFSNGLVTVMVPQLRRENSLLLWNVFDLNTPVHTFVGHDDVVLEFQWRKQKEGSKDYQLVTWSRDQTLRMWRIDSQLQRLCANDILDGVDDLIDGISLLPEPDKALQPQDSEPQHSSGHGDEEALKEDFLNDLLVGKKTDQLGLPQTLQQEFSLINVQIRNVNVEMDAVNRSCTVSVHCGNHRVRMLVMFPVQYPNNAAPSFQFINPTSITASMKAKLLKILKDTSLQKVKRNQSCLEPCLRQLVSWLESVVNQEDSTSSNPYALPNSVTTPLPTFARVSNAYGSYQDSNIPFPRTSGARFCGAGYLVYFTRPMTMHRAVSPTEPTPRSLSALSAYHSGLITPMKIRTETPGNLRLYSGSPTRSEKEQVSISSFYYKERMSPRSARRRWSIQAINDFPKSRRWKSKREGTDANNRPIKAAGKVIIQDISCLLPVHKLLGELYILNVNNIQETCQKNAASAMAVGRRDLVQVWSLAMVATDLCLGPKSDPDLEIPWAQHPFGRQLLESLLAHYSQLHDVQTLAMLCSVFEAQSRLQGCPNSYGPFPQRASNLASHSRYPSFTSSGSCSSMSDPGLGTGGWSIANKDTEQTSTPWCESSPDEFRYSNLMYPDHREREKDQHEKNKRLLDPANTQQFDDFKKCYGEILYRWGLREKRAEVLKFVSSPPDPHKGIEFGVYCSHCRSEARGTQCAICKGFTFQCAICHVAVRGSSNFCLTCGHGGHTSHMMEWFRTQEVCPTGCGCHCLLESTF", "length": 992, "header": "tr|A0A8V0ZMI1-1|A0A8V0ZMI1_CHICK Isoform 1 of GATOR2 complex protein WDR59 OS=Gallus gallus OX=9031 GN=WDR59 PE=3 SV=1 CANONICAL=A0A8V0ZMI1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1/entry#A0A8V0ZMI1-1", "sequence": { "sequence": "MAARWSSENVVVEFRDAQATAMSVDCLGQHAVLSGRRFLYIVNLDAPNEGHRKISRQSKWDIGAVQWNPHDSYAYYFAASSNQRVDLYKWKEGNGEVCTSLQGHTRVISDLDWSVFEPDLLVTSSVDTYIYIWDIKDTRKPTVSLSAVAGASQVKWNKKNANCLATSHDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDNEYTLATSSQDNSVRFWDYRQPRKYLNILPCQVPVWKARYTPFSNGLVTVMVPQLRRENSLLLWNVFDLNTPVHTFVGHDDVVLEFQWRKQKEGSKDYQLVTWSRDQTLRMWRIDSQLQRLCANDILDGVDDLIDGISLLPEPDKALQPQDSEPQHSSGHGDEEALKEDFLNDLLVGKKTDQLGLPQTLQQEFSLINVQIRNVNVEMDAVNRSCTVSVHCGNHRVRMLVMFPVQYPNNAAPSFQFINPTSITASMKAKLLKILKDTSLQKVKRNQSCLEPCLRQLVSWLESVVNQEDSTSSNPYALPNSVTTPLPTFARVSNAYGSYQDSNIPFPRTSGARFCGAGYLVYFTRPMTMHRAVSPTEPTPRSLSALSAYHSGLITPMKIRTETPGNLRLYSGSPTRSEKEQVSISSFYYKERMSPRSARRRWSIQAINDFPKSRRWKSKREGTDANNRPIKAAGKVIIQDISCLLPVHKLLGELYILNVNNIQETCQKNAASAMAVGRRDLVQVWSLAMVATDLCLGPKSDPDLEIPWAQHPFGRQLLESLLAHYSQLHDVQTLAMLCSVFEAQSRLQGCPNSYGPFPQRASNLASHSRYPSFTSSGSCSSMSDPGLGTGGWSIANKDTEQTSTPWCESSPDEFRYSNLMYPDHREREKDQHEKNKRLLDPANTQQFDDFKKCYGEILYRWGLREKRAEVLKFVSSPPDPHKGIEFGVYCSHCRSEARGTQCAICKGFTFQCAICHVAVRGSSNFCLTCGHGGHTSHMMEWFRTQEVCPTGCGCHCLLESTF", "length": 992, "header": "tr|A0A8V0ZMI1-1|A0A8V0ZMI1_CHICK Isoform 1 of GATOR2 complex protein WDR59 OS=Gallus gallus OX=9031 GN=WDR59 PE=3 SV=1 CANONICAL=A0A8V0ZMI1-1" }, "locus": { "chromosome": "11", "start_pos": 1970729, "end_pos": 1923337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056888.1", "url": "https://www.ensembl.org/id/ENSGALT00010056888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034595.1", "url": "https://www.ensembl.org/id/ENSGALP00010034595.1" } ] } }, { "isoform_ac": "A0A8V0ZSR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1/entry#A0A8V0ZSR1-1", "sequence": { "sequence": "MCKAVLSVGEDLLSGSSDMKATAMSVDCLGQHAVLSGRRFLYIVNLDAPNEGHRKISRQSKWDIGAVQWNPHDSYAYYFAASSNQRVDLYKWKEGNGEVCTSLQGHTRVISDLDWSVFEPDLLVTSSVDTYIYIWDIKDTRKPTVSLSAVAGASQVKWNKKNANCLATSHDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDNEYTLATSSQDNSVRFWDYRQPRKYLNILPCQVPVWKARYTPFSNGLVTVMVPQLRRENSLLLWNVFDLNTPVHTFVGHDDVVLEFQWRKQKEGSKDYQLVTWSRDQTLRMWRIDSQLQRLCANDILDGVDDLIDGISLLPEPDKALQPQDSEPQHSSGHGDEEALKEDFLNDLLVGKKTDQLGLPQTLQQEFSLINVQIRNVNVEMDAVNRSCTVSVHCGNHRVRMLVMFPVQYPNNAAPSFQFINPTSITASMKAKLLKILKDTSLQKVKRNQSCLEPCLRQLVSWLESVVNQEDSTSSNPYALPNSVTTPLPTFARVSNAYGSYQDSNIPFPRTSGARFCGAGYLVYFTRPMTMHRAVSPTEPTPRSLSALSAYHSGLITPMKIRTETPGNLRLYSGSPTRSEKEQVSISSFYYKERKSRRWKSKREGTDANNRPIKAAGKVIIQDISCLLPVHKLLGELYILNVNNIQETCQKNAASAMAVGRRDLVQVWSLAMVATDLCLGPKSDPDLEIPWAQHPFGRQLLESLLAHYSQLHDVQTLAMLCSVFEAQSRLQGCPNSYGPFPQRASNLASHSRYPSFTSSGSCSSMSDPGLGTGGWSIANKDTEQTSTPWCESSPDEFRYSNLMYPDHREREKDQHEKNKRLLDPANTQQFDDFKKCYGEILYRWGLREKRAEVLKFVSSPPDPHKGIEFGVYCSHCRSEARGTQCAICKGFTFQCAICHVAVRGSSNFCLTCGHGGHTSHMMEWFRTQEVCPTGCGCHCLLESTF", "length": 975, "header": "tr|A0A8V0ZSR1-1|A0A8V0ZMI1_CHICK Computationally mapped isoform of GATOR2 complex protein WDR59 OS=Gallus gallus OX=9031 GN=WDR59 PE=3 SV=1 CANONICAL=A0A8V0ZMI1-1" }, "locus": { "chromosome": "11", "start_pos": 1969834, "end_pos": 1923337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056884.1", "url": "https://www.ensembl.org/id/ENSGALT00010056884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034592.1", "url": "https://www.ensembl.org/id/ENSGALP00010034592.1" } ] } }, { "isoform_ac": "A0A8V0ZUT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1/entry#A0A8V0ZUT0-1", "sequence": { "sequence": "YIVNLDAPNEGHRKISRQSKWDIGAVQWNPHDSYAYYFAASSNQRVDLYKWKEGNGEVCTSLQGHTRVISDLDWSVFEPDLLVTTGASQVKWNKKNANCLATSHDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDNEYTLATSSQDNSVRVSIASGTFAWEVSGWWGRFPFPFSNGLVTVMVPQLRRENSLLLWNVFDLNTPVHTFVGHDDVVLEFQWRKQKEGSKDYQLVTWSRDQTLRMWRIDSQLQRLCANDILDGVDDLIDGISLLPEPDKALQPQDSEPQHSSGHGDEEALKEDFLNDLLVGKKTDQLGLPQTLQQEFSLINVQIRNVNVEMDAVNRSCTVSVHCGNHRVRMLVMFPVQYPNNAAPSFQFINPTSITASMKAKLLKILKDTSLQKVKRNQSCLEPCLRQLVSWLESVVNQEDSTSSNPYALPNSVTTPLPTFARVSNAYGSYQDSNIPFPRTSGARFCGAGYLVYFTRPMTMHRAVSPTEPTPRSLSALSAYHSGLITPMKIRTETPGNLRLYSGSPTRSEKEQVSISSFYYKERKSRRWKSKREGTDANNRPIKAAGKVIIQDISCLLPVHKLLGELYILNVNNIQETCQKNAASAMAVGRRDLVQVWSLAMVATDLCLGPKSDPDLEIPWAQHPFGRQLLESLLAHYSQLHDVQTLAMLCSVFEAQSRLQGCPNSYGPFPQRASNLASHSRYPSFTSSGSCSSMSDPGLGTGGWSIANKDTEQTSTPWCESSPDEFRYSNLMYPDHREREKDQHEKNKRLLDPANTQQFDDFKKCYGEILYRWGLREKRAEVLKFVSSPPDPHKGIEFGVYCSHCRSEARGTQCAICKGFTFQCAICHVAVRGSSNFCLTCGHGGHTSHMMEWFRTQEVCPTGCGCHCLLESTF", "length": 904, "header": "tr|A0A8V0ZUT0-1|A0A8V0ZMI1_CHICK Computationally mapped isoform of GATOR2 complex protein WDR59 OS=Gallus gallus OX=9031 GN=WDR59 PE=3 SV=1 CANONICAL=A0A8V0ZMI1-1" }, "locus": { "chromosome": "11", "start_pos": 1964542, "end_pos": 1923337, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056900.1", "url": "https://www.ensembl.org/id/ENSGALT00010056900.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034599.1", "url": "https://www.ensembl.org/id/ENSGALP00010034599.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 566, "start_aa": "Thr", "end_pos": 566, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr566", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 569, "start_aa": "Thr", "end_pos": 569, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr569", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-9639288", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9639288", "resource": "Reactome", "description": "Amino acids regulate mTORC1" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1" } ], "pmid": "" }, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1" } ], "pmid": "" }, { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1" } ], "pmid": "" }, { "name": "GATOR2 complex", "id": "GO:0061700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1" } ], "pmid": "" }, { "name": "Seh1-associated complex", "id": "GO:0035859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035859", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMI1" }, { "id": "PS50908", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RWD", "eco_id": "ECO_0000259", "start_pos": 393, "end_pos": 494, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 566, 569 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 413, "end_pos": 415 }, { "start_pos": 476, "end_pos": 478 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", 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{ "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMJ0-1", "uniprot_ac": "A0A8V0ZMJ0", "uniprot_id": "A0A8V0ZMJ0_CHICK", "mass": { "chemical_mass": 64217.0, "monoisotopic_mass": 64217.0 }, "refseq": {}, "gene_names": [ { "name": "PLIN1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0" } ] } ], "protein_names": [ { "name": "Perilipin 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0", "locus": { "chromosome": "10", "start_pos": 12839881, "end_pos": 12835100, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010020954", "url": "https://www.ensembl.org/id/ENSGALG00010020954" } ] } } ], "crossref": [ { "id": "A0A8V0ZMJ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMJ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZMJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47138:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47138:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTCGELFARFPQQLMPPSPAQRWGLGVVVPQHHTPQAQDPSEDRLLRSSSRGGVCGALALGFNCSALCFAGGRGMMTAKKNQPLQNGRAKENVLQRVLQLPVVSSTCESLQRTYTSTKEVHPFVASVCEVYEQGVKGASALAMWSMEPVVRRLEPQFSMANTLACRGLDHLEEKIPALQYPVDKLASKLKDTISSPIQCAKSTIGNSMDKILGLAVGGYETTKSTVETTARYTRSNSVSQMAAAGMDTALGGLEKLMEYLLPEEEEEDLKPKQTCGPAAKVSQQQSRAYRAHSAPSAPSSAPSTLGRIGALLSTASHRAYQHTAQNLQRAKAKGQELVVWIPILGSLAKPSPPVVPQSHGERQSIAGSWRQSRMPEQKPEKAEKKEDSHAGEAGDGLGLVGSVAHNLQSACASGISSVKKVPAVAWDAAEGLILFTPRRLSRAMETVDALGGTLISAPKHLLGSLYSLVPLRRQSKDEAAARGSKTCPEAEQKEEESKPADTSAEEKAQLRGDWRLYRGHHPLSFLGLEDPLFIRSNLYRSSALEPEAVPRKSAFAPYSRRVSEGSYRFSPEAMYSRAYYANLYGPAYKKD", "length": 592, "header": "tr|A0A8V0ZMJ0-1|A0A8V0ZMJ0_CHICK Isoform 1 of Perilipin 1 OS=Gallus gallus OX=9031 GN=PLIN1 PE=3 SV=1 CANONICAL=A0A8V0ZMJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0/entry#A0A8V0ZMJ0-1", "sequence": { "sequence": "MRTCGELFARFPQQLMPPSPAQRWGLGVVVPQHHTPQAQDPSEDRLLRSSSRGGVCGALALGFNCSALCFAGGRGMMTAKKNQPLQNGRAKENVLQRVLQLPVVSSTCESLQRTYTSTKEVHPFVASVCEVYEQGVKGASALAMWSMEPVVRRLEPQFSMANTLACRGLDHLEEKIPALQYPVDKLASKLKDTISSPIQCAKSTIGNSMDKILGLAVGGYETTKSTVETTARYTRSNSVSQMAAAGMDTALGGLEKLMEYLLPEEEEEDLKPKQTCGPAAKVSQQQSRAYRAHSAPSAPSSAPSTLGRIGALLSTASHRAYQHTAQNLQRAKAKGQELVVWIPILGSLAKPSPPVVPQSHGERQSIAGSWRQSRMPEQKPEKAEKKEDSHAGEAGDGLGLVGSVAHNLQSACASGISSVKKVPAVAWDAAEGLILFTPRRLSRAMETVDALGGTLISAPKHLLGSLYSLVPLRRQSKDEAAARGSKTCPEAEQKEEESKPADTSAEEKAQLRGDWRLYRGHHPLSFLGLEDPLFIRSNLYRSSALEPEAVPRKSAFAPYSRRVSEGSYRFSPEAMYSRAYYANLYGPAYKKD", "length": 592, "header": "tr|A0A8V0ZMJ0-1|A0A8V0ZMJ0_CHICK Isoform 1 of Perilipin 1 OS=Gallus gallus OX=9031 GN=PLIN1 PE=3 SV=1 CANONICAL=A0A8V0ZMJ0-1" }, "locus": { "chromosome": "10", "start_pos": 12839144, "end_pos": 12835219, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050635.1", "url": "https://www.ensembl.org/id/ENSGALT00010050635.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010029894.1", "url": "https://www.ensembl.org/id/ENSGALP00010029894.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0" } ], "pmid": "" }, { "name": "negative regulation of triglyceride catabolic process", "id": "GO:0010897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMJ3-1", "uniprot_ac": "A0A8V0ZMJ3", "uniprot_id": "A0A8V0ZMJ3_CHICK", "mass": { "chemical_mass": 30673.0, "monoisotopic_mass": 30673.0 }, "refseq": {}, "gene_names": [ { "name": "LOC107057318", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ3" } ] } ], "protein_names": [ { "name": "Fat storage inducing transmembrane protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107057318", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZMJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMJ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZMJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSS3", "url": "https://www.orthodb.org/?gene=A0A8V0ZSS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZW21", "url": "https://www.orthodb.org/?gene=A0A8V0ZW21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23129:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23129:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8964572", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8964572", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZMJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERLERCARCLRARLVAAAVRRRLPWLLLGLVFLGSALKDGDLVPETPMQNKRNVYFVKVAWAWTFWLLLPFIGVTTYLFAKSKFLYGPTKSILAALRRLSTLLVGTAVWYVCTELFVYIENLTGTCSTSSKLSEPHQLYATKQECHRNNGIWNGFDISGHCFLLSYCALMIVEEMAVLEGLSIDRNSRLRVVINGLFVSLCFLTMIWVFMFLCTTVYFHDFSQKLLGALIGLAAWYATYRVWYLKPFSPGLPLPNIPLSSKKYSYSR", "length": 268, "header": "tr|A0A8V0ZMJ3-1|A0A8V0ZMJ3_CHICK Isoform 1 of Fat storage inducing transmembrane protein 2 OS=Gallus gallus OX=9031 GN=LOC107057318 PE=3 SV=1 CANONICAL=A0A8V0ZMJ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ3/entry#A0A8V0ZMJ3-1", "sequence": { "sequence": "MERLERCARCLRARLVAAAVRRRLPWLLLGLVFLGSALKDGDLVPETPMQNKRNVYFVKVAWAWTFWLLLPFIGVTTYLFAKSKFLYGPTKSILAALRRLSTLLVGTAVWYVCTELFVYIENLTGTCSTSSKLSEPHQLYATKQECHRNNGIWNGFDISGHCFLLSYCALMIVEEMAVLEGLSIDRNSRLRVVINGLFVSLCFLTMIWVFMFLCTTVYFHDFSQKLLGALIGLAAWYATYRVWYLKPFSPGLPLPNIPLSSKKYSYSR", "length": 268, "header": "tr|A0A8V0ZMJ3-1|A0A8V0ZMJ3_CHICK Isoform 1 of Fat storage inducing transmembrane protein 2 OS=Gallus gallus OX=9031 GN=LOC107057318 PE=3 SV=1 CANONICAL=A0A8V0ZMJ3-1" }, "locus": { "chromosome": "20", "start_pos": 5811308, "end_pos": 5808810, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056908.1", "url": "https://www.ensembl.org/id/ENSGALT00010056908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034605.1", "url": "https://www.ensembl.org/id/ENSGALP00010034605.1" } ] } }, { "isoform_ac": "A0A8V0ZSS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ3/entry#A0A8V0ZSS3-1", "sequence": { "sequence": "MLRCGGLRMPKGCHRLKTQQSGCYLCCFIDFLRYFVKVAWAWTFWLLLPFIGVTTYLFAKSKFLYGPTKSILAALRRLSTLLVGTAVWYVCTELFVYIENLTGTCSTSSKLSEPHQLYATKQECHRNNGIWNGFDISGHCFLLSYCALMIVEEMAVLEGLSIDRNSRLRVVINGLFVSLCFLTMIWVFMFLCTTVYFHDFSQKLLGALIGLAAWYATYRVWYLKPFSPGLPLPNIPLSSKKYSYSR", "length": 246, "header": "tr|A0A8V0ZSS3-1|A0A8V0ZMJ3_CHICK Computationally mapped isoform of Fat storage inducing transmembrane protein 2 OS=Gallus gallus OX=9031 GN=LOC107057318 PE=3 SV=1 CANONICAL=A0A8V0ZMJ3-1" }, "locus": { "chromosome": "20", "start_pos": 5811308, "end_pos": 5810028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056904.1", "url": "https://www.ensembl.org/id/ENSGALT00010056904.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034602.1", "url": "https://www.ensembl.org/id/ENSGALP00010034602.1" } ] } }, { "isoform_ac": "A0A8V0ZW21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMJ3/entry#A0A8V0ZW21-1", "sequence": { "sequence": "CLSAPIGSEAVSAQVSYCWSADSSPVSSLFGLYFVKVAWAWTFWLLLPFIGVTTYLFAKSKFLYGPTKSILAALRRLSTLLVGTAVWYVCTELFVYIENLTGTCSTSSKLSEPHQLYATKQECHRNNGIWNGFDISGHCFLLSYCALMIVEEMAVLEGLSIDRNSRLRVVINGLFVSLCFLTMIWVFMFLCTTVYFHDFSQKLLGALIGLAAWYATYRVWYLKPFSPGLPLPNIPLSSKKYSYSR", "length": 245, "header": "tr|A0A8V0ZW21-1|A0A8V0ZMJ3_CHICK Computationally mapped isoform of Fat storage inducing transmembrane protein 2 OS=Gallus gallus OX=9031 GN=LOC107057318 PE=3 SV=1 CANONICAL=A0A8V0ZMJ3-1" }, "locus": { "chromosome": "20", "start_pos": 5811308, "end_pos": 5809383, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056905.1", "url": "https://www.ensembl.org/id/ENSGALT00010056905.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034603.1", "url": "https://www.ensembl.org/id/ENSGALP00010034603.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8964572", "name": "", "url": 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This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_415279.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_415279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415279" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN7", "locus": { "chromosome": "15", "start_pos": 9678623, "end_pos": 9723714, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023379", "url": "https://www.ensembl.org/id/ENSGALG00010023379" } ] } } ], "crossref": [ { "id": "A0A8V0ZMN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "416987", "url": "https://www.ncbi.nlm.nih.gov/gene/416987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416987", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416987", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MWELFIT", "url": "https://omabrowser.org/oma/group/MWELFIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMN2", "url": "https://www.orthodb.org/?gene=A0A8V0ZMN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMN7", "url": "https://www.orthodb.org/?gene=A0A8V0ZMN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMP2", "url": "https://www.orthodb.org/?gene=A0A8V0ZMP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSX2", "url": "https://www.orthodb.org/?gene=A0A8V0ZSX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34754", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34754", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34754:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34754:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15769", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15769", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_415279", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_415279", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMN2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAPGVPKLSRAEAPVALNAQLGAAAPPEPPKDGGTKVPAAGKALNPRDFVRVQPLPALAEGEGKVLARSWALYRSSGPPSERVFWEQRQRRERQRTQGLFTPRGKPYQELGELLCADPKQLTLLSLGQLAQEPVKKDMQERPQREVAEVTANESSVNPKSAPVESVKRLTSSRETGTELKTLSKTLARLRRHINTVKQGGEYFHILHQESLEQKNALKAQKSQTTIWRTDFQPCEYSSEVEVSDEEMNSSSPIEGSHPKKSGKKKKMTLRSYTPVYTSVLIARPSEAQSECLFRQLCAIHWLLEALTLESSSSMHSILSCWKLTDPGGFKKSVKEIEEEKFTTYMWELFLTNTKKYMRKARRIPFRRQTNKAAAPASSQLSTQSSHGQTPLSSVSSLVLCSEDNINLSGALADDTRASMQTKEQPFFPFPQKQIQTTHVKASKDAREQEDMLKKTGLQSCRISQFIKSKSNLCADARHQFMAIREEAAHRLHDALESLERTQEERCCQKYLALKRLKYFKEDMERIRQLDVRAEREHDENGPKWFPALLARLPEHVKNDCYVKKILKKLEKFGLAPDLHIDQDTFLKAAADLQLWELCCPDIAAAVEFVRESIVQMPEEDFSEWFQERVDHLHAQSSAF", "length": 640, "header": "tr|A0A8V0ZMN7-1|A0A8V0ZMN7_CHICK Isoform 1 of Coiled-coil domain containing 60 OS=Gallus gallus OX=9031 GN=CCDC60 PE=4 SV=1 CANONICAL=A0A8V0ZMN7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN7/entry#A0A8V0ZMN2-1", "sequence": { "sequence": "MPAPGVPKLSRAEAPVALNAQLGAAAPPEPPKDGGTKVPAAGKALNPRDFVRVQPLPALAEGEGKVLARSWALYRSSGPPSERVFWEQRQRRERQRTQGLFTPRGKPYQELGELLCADPKQLTLLSLGQLAQEPVKKDMQERPQREVAEVTANESSVNPKSAPVESVKRLTSSRETGTELKTLSKTLARLRRHINTVKQGGEYFHILHQESLEQKNALKAQKSQTTIWRTDFQPCEYSSEVEVSDEEMNSSSPIEGSHPKKSGKKKKMTLRSYTPVYTSVLIARPSEAQRDPGGFKKSVKEIEEEKFTTYMWELFLTNTKKYMRKARRIPFRRQTNKAAAPASSQLSTQSSHGQTPLSSVSSLVLCSEDNINLSGALADDTRASMQTKEQPFFPFPQKQIQTTHVKASKDAREQEDMLKKTGLQSCRISQFIKSKSNLCADARHQFMAIREEAAHRLHDALESLERTQEERCCQKYLALKRLKYFKEDMERIRQLDVRAEREHDENGPKWFPALLARLPEHVKNDCYVKKILKKLEKFGLAPDLHIDQDTFLKAAADLQLWELCCPDIAAAVEFVRESIVQMPEEDFSEWFQERVDHLHAQSSAF", "length": 605, "header": "tr|A0A8V0ZMN2-1|A0A8V0ZMN7_CHICK Computationally mapped isoform of Coiled-coil domain containing 60 OS=Gallus gallus OX=9031 GN=CCDC60 PE=4 SV=1 CANONICAL=A0A8V0ZMN7-1" }, "locus": { "chromosome": "15", "start_pos": 9722419, "end_pos": 9679273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056983.1", "url": "https://www.ensembl.org/id/ENSGALT00010056983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034650.1", "url": "https://www.ensembl.org/id/ENSGALP00010034650.1" } ] } }, { "isoform_ac": "A0A8V0ZMN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN7/entry#A0A8V0ZMN7-1", "sequence": { "sequence": "MPAPGVPKLSRAEAPVALNAQLGAAAPPEPPKDGGTKVPAAGKALNPRDFVRVQPLPALAEGEGKVLARSWALYRSSGPPSERVFWEQRQRRERQRTQGLFTPRGKPYQELGELLCADPKQLTLLSLGQLAQEPVKKDMQERPQREVAEVTANESSVNPKSAPVESVKRLTSSRETGTELKTLSKTLARLRRHINTVKQGGEYFHILHQESLEQKNALKAQKSQTTIWRTDFQPCEYSSEVEVSDEEMNSSSPIEGSHPKKSGKKKKMTLRSYTPVYTSVLIARPSEAQSECLFRQLCAIHWLLEALTLESSSSMHSILSCWKLTDPGGFKKSVKEIEEEKFTTYMWELFLTNTKKYMRKARRIPFRRQTNKAAAPASSQLSTQSSHGQTPLSSVSSLVLCSEDNINLSGALADDTRASMQTKEQPFFPFPQKQIQTTHVKASKDAREQEDMLKKTGLQSCRISQFIKSKSNLCADARHQFMAIREEAAHRLHDALESLERTQEERCCQKYLALKRLKYFKEDMERIRQLDVRAEREHDENGPKWFPALLARLPEHVKNDCYVKKILKKLEKFGLAPDLHIDQDTFLKAAADLQLWELCCPDIAAAVEFVRESIVQMPEEDFSEWFQERVDHLHAQSSAF", "length": 640, "header": "tr|A0A8V0ZMN7-1|A0A8V0ZMN7_CHICK Isoform 1 of Coiled-coil domain containing 60 OS=Gallus gallus OX=9031 GN=CCDC60 PE=4 SV=1 CANONICAL=A0A8V0ZMN7-1" }, "locus": { "chromosome": "15", "start_pos": 9722419, "end_pos": 9679273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056987.1", "url": "https://www.ensembl.org/id/ENSGALT00010056987.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034655.1", "url": "https://www.ensembl.org/id/ENSGALP00010034655.1" } ] } }, { "isoform_ac": "A0A8V0ZMP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN7/entry#A0A8V0ZMP2-1", "sequence": { "sequence": "MQERPQREVAEVTANESSVNPKSAPVESVKRLTSSRETGTELKTLSKTLARLRRHINTVKQGGEYFHILHQESLEQKNALKAQKSQTTIWRTDFQPCEYSSEVEVSDEEMNSSSPIEGSHPKKSGKKKKMTLRSYTPVYTSVLIARPSEAQSECLFRQLCAIHWLLEALTLESSSSMHSILSCWKLTDPGGFKKSVKEIEEEKFTTYMWELFLTNTKKYMRKARRIPFRRQTNKAAAPASSQLSTQSSHGQTPLSSVSSLVLCSEDNINLSGALADDTRASMQTKEQPFFPFPQKQIQTTHVKASKDAREQEDMLKKTGLQSCRISQFIKSKSNLCADARHQFMAIREEAAHRLHDALESLERTQEERCCQKYLALKRLKYFKEDMERIRQLDVRAEREHDENGPKWFPALLARLPEHVKNDCYVKKILKKLEKFGLAPDLHIDQDTFLKAAADLQLWELCCPDIAAAVEFVRESIVQMPEEDFSEWFQERVDHLHAQSSAF", "length": 502, "header": "tr|A0A8V0ZMP2-1|A0A8V0ZMP2_CHICK Computationally mapped isoform of Coiled-coil domain containing 60 OS=Gallus gallus OX=9031 GN=CCDC60 PE=4 SV=1 CANONICAL=A0A8V0ZMN7-1" }, "locus": { "chromosome": "15", "start_pos": 9703203, "end_pos": 9679273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056994.1", "url": "https://www.ensembl.org/id/ENSGALT00010056994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034660.1", "url": "https://www.ensembl.org/id/ENSGALP00010034660.1" } ] } }, { "isoform_ac": "A0A8V0ZSX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN7/entry#A0A8V0ZSX2-1", "sequence": { "sequence": "MEPVKKDMQERPQREVAEVTANESSVNPKSAPVESVKRLTSSRETGTELKTLSKTLARLRRHINTVKQGGEYFHILHQESLEQKNALKAQKSQTTIWRTDFQPCEYSSEVEVSDEEMNSSSPIEGSHPKKSGKKKKMTLRSYTPVYTSVLIARPSEAQSECLFRQLCAIHWLLEALTLESSSSMHSILSCWKLTDPGGFKKSVKEIEEEKFTTYMWELFLTNTKKYMRKARRIPFRRQTNKAAAPASSQLSTQSSHGQTPLSSVSSLVLCSEDNINLSGALADDTRASMQTKEQPFFPFPQKQIQTTHVKASKDAREQEDMLKKTGLQSCRISQFIKSKSNLCADARHQFMAIREEAAHRLHDALESLERTQEERCCQKYLALKRLKYFKEDMERIRQLDVRAEREHDENGPKWFPALLARLPEHVKNDCYVKKILKKLEKFGLAPDLHIDQDTFLKAAADLQLWELCCPDIAAAVEFVRESIVQMPEEDFSEWFQERVDHLHAQSSAF", "length": 509, "header": "tr|A0A8V0ZSX2-1|A0A8V0ZMN7_CHICK Computationally mapped isoform of Coiled-coil domain containing 60 OS=Gallus gallus OX=9031 GN=CCDC60 PE=4 SV=1 CANONICAL=A0A8V0ZMN7-1" }, "locus": { "chromosome": "15", "start_pos": 9720806, "end_pos": 9679273, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056989.1", "url": "https://www.ensembl.org/id/ENSGALT00010056989.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034657.1", "url": "https://www.ensembl.org/id/ENSGALP00010034657.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416987", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416987", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 407, "end_pos": 409 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMN5-1", "uniprot_ac": "A0A8V0ZMN5", "uniprot_id": "A0A8V0ZMN5_CHICK", "mass": { "chemical_mass": 67979.0, "monoisotopic_mass": 67979.0 }, "refseq": { "ac": "XP_003642573", "name": "pleckstrin homology domain-containing family N member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642573" }, "gene_names": [ { "name": "PLEKHN1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN5" } ] }, { "name": "PLEKHN1", "type": "synonym", "evidence": [ { "id": "XP_003642573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642573" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain containing N1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN5/entry#names_and_taxonomy" } ] }, { "name": "pleckstrin homology domain-containing family N member 1", "type": "synonym", "evidence": [ { "id": "XP_003642573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642573" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642573.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642573" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN5", "locus": { "chromosome": "21", "start_pos": 2846542, "end_pos": 2859355, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021877", "url": "https://www.ensembl.org/id/ENSGALG00010021877" } ] } } ], "crossref": [ { "id": "A0A8V0ZMN5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMN5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13323", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13323", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "771179", "url": "https://www.ncbi.nlm.nih.gov/gene/771179", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:771179", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:771179", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HVLCPSQ", "url": "https://omabrowser.org/oma/group/HVLCPSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMN5", "url": "https://www.orthodb.org/?gene=A0A8V0ZMN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46882", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46882", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46882:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46882:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_003642573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMN5-1", "database": 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Classification" ] }, { "id": "IPR036531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMQ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZMQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13510", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13510", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13510:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13510:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11464", "url": 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"MASGCAPPFGDAAEMREGFLCPLCLKDLQAFQQLRAHYEEEHSGEDRDVRGQIRSLVQKAKRAKKKLLKREGDDRTDSGSQERYESFSYGGIDPYMWEPQEVGAMRSHLSSFKKYRAARIDHYVVEVNKLLIRLEKLTSFDRANTESAKIRAIEKSVVPWVNDQDVPFCPDCGNKFSMRNRRHHCRLCGSIMCKKCMELISLPLASKCGKLTSASKEALSSLTSPNASPNSVHGSRRGSISSISSVSSVLDEKDDDQIRCCQHCKDTLLKREQQIDEKDYTPEIVKLYEKLRLCMEKVDQKAPEYVRMAESLNAGETTYSLEHANDLRVEIQKVYEFIDALSKKILSLGLHEEPQPHPKTLQLQRMIRYSATLFVQEKLFGLMSLPTKDQYEELKKRRLHMAALETHRKQEEKQKDLIYRSAAAVNGDATLLKKGTVRKSEGWLPTSSVSRQSEVADPLLQQIDNITSFIKQAKAANRLDEVRMLQENLRQLQDEYDQQQTLKAIELSKKQAEEEEKQREELQFLCEKEWEREHHKFMSQRSRTGSLDFREGKQHQYEAAKENQNLLAHGLDLDITQVKGNRSFETTAVQQLPAKEYLIFPVRHQNTPRCDKDQNQAACLNPFEDDADTPLSEEDPTNPFAKDVSQPISFSNTALQSDKKEYNPFENEEEGEQTSGASVSTLNPFEEDENPFQKSGSNWNSGNPFEESSSTNPFEVEDVSEILREEAIEEELLLQQIDNIKAYIFDAKHSGRMDEVELLTENLKELKYTLAKQKEKYNC", "length": 779, "header": "tr|A0A8V0ZMQ4-1|A0A8V0ZMQ4_CHICK Isoform 1 of Rabenosyn, RAB effector OS=Gallus gallus OX=9031 GN=RBSN PE=1 SV=1 CANONICAL=A0A8V0ZMQ4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ4/entry#A0A8V0ZMQ4-1", "sequence": { "sequence": "MASGCAPPFGDAAEMREGFLCPLCLKDLQAFQQLRAHYEEEHSGEDRDVRGQIRSLVQKAKRAKKKLLKREGDDRTDSGSQERYESFSYGGIDPYMWEPQEVGAMRSHLSSFKKYRAARIDHYVVEVNKLLIRLEKLTSFDRANTESAKIRAIEKSVVPWVNDQDVPFCPDCGNKFSMRNRRHHCRLCGSIMCKKCMELISLPLASKCGKLTSASKEALSSLTSPNASPNSVHGSRRGSISSISSVSSVLDEKDDDQIRCCQHCKDTLLKREQQIDEKDYTPEIVKLYEKLRLCMEKVDQKAPEYVRMAESLNAGETTYSLEHANDLRVEIQKVYEFIDALSKKILSLGLHEEPQPHPKTLQLQRMIRYSATLFVQEKLFGLMSLPTKDQYEELKKRRLHMAALETHRKQEEKQKDLIYRSAAAVNGDATLLKKGTVRKSEGWLPTSSVSRQSEVADPLLQQIDNITSFIKQAKAANRLDEVRMLQENLRQLQDEYDQQQTLKAIELSKKQAEEEEKQREELQFLCEKEWEREHHKFMSQRSRTGSLDFREGKQHQYEAAKENQNLLAHGLDLDITQVKGNRSFETTAVQQLPAKEYLIFPVRHQNTPRCDKDQNQAACLNPFEDDADTPLSEEDPTNPFAKDVSQPISFSNTALQSDKKEYNPFENEEEGEQTSGASVSTLNPFEEDENPFQKSGSNWNSGNPFEESSSTNPFEVEDVSEILREEAIEEELLLQQIDNIKAYIFDAKHSGRMDEVELLTENLKELKYTLAKQKEKYNC", "length": 779, "header": "tr|A0A8V0ZMQ4-1|A0A8V0ZMQ4_CHICK Isoform 1 of Rabenosyn, RAB effector OS=Gallus gallus OX=9031 GN=RBSN PE=1 SV=1 CANONICAL=A0A8V0ZMQ4-1" }, "locus": { "chromosome": "12", "start_pos": 19913352, "end_pos": 19902322, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053258.1", "url": "https://www.ensembl.org/id/ENSGALT00010053258.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032097.1", "url": "https://www.ensembl.org/id/ENSGALP00010032097.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-983231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983231", "resource": "Reactome", "description": "Factors involved in megakaryocyte development and platelet production" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ4" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "Golgi to lysosome transport", "id": "GO:0090160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ4" } ], "pmid": "" }, { "name": "early endosome to Golgi transport", "id": "GO:0034498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034498", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ4" } ], "pmid": "" }, { "name": "regulation of Golgi organization", "id": "GO:1903358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903358", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 47, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMQ4" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 163, "end_pos": 269, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 581, "end_pos": 583 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZMT9-1", "uniprot_ac": "A0A8V0ZMT9", "uniprot_id": "A0A8V0ZMT9_CHICK", "mass": { "chemical_mass": 144225.0, "monoisotopic_mass": 144225.0 }, "refseq": { "ac": "XP_040562479", "name": "zinc finger protein 592", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562479" }, "gene_names": [ { "name": "ZNF592", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9" } ] }, { "name": "ZNF592", "type": "synonym", "evidence": [ { "id": "XP_040562479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562479" } ] } ], "protein_names": [ { "name": "Zinc finger protein 592", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 592", "type": "synonym", "evidence": [ { "id": "XP_040562479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562479" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040562479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562479" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF592", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9", "locus": { "chromosome": "10", "start_pos": 1027964, "end_pos": 994149, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022312", "url": "https://www.ensembl.org/id/ENSGALG00010022312" } ] } } ], "crossref": [ { "id": "415335", "url": "https://www.ncbi.nlm.nih.gov/gene/415335", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415335", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415335", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SVKKYPC", "url": "https://omabrowser.org/oma/group/SVKKYPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMT9", "url": "https://www.orthodb.org/?gene=A0A8V0ZMT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47222:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47222:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9940951", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040562479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562479", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDPTSLDAKETIPSAGEENENHLKSSGICIDENVSLSHSLPPSDAPVVSVIVKNTSRQESFEAEKEGNHLGTGLLHNGFRGSDLPSEAHALVHNYGKFESTFINGDSSRSYSEKLDQSKSEPLPTFSQFSPISSPEPEDTFKENSIGDKPKHAQTPYFPPPSMYMPTGASVLDHFRKVPEPELSMFDQYCKKEQKMEIHFQPESRQEMSRREQDKATERFVESGKDLVDTNSFLGEGLVFGELPHSNLGEDKGSVPELNLSSSVPPRQRLKPTHSKLSSCVAALVALQAKKVACIPKGDQPNLIKEPGPFKDGTKGSPKMPKSPKSPRSPLEVVRKASKQPESPRSVCSDSSGKGSPSMAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPESDELGKSLEESPLETSSAEEFIKSFPSPDTSAVMESEASKNSTKNGAAIAIQLSNIVSPYTDGLKADLAANTTSLVSLSPLPNCGGGAIKVGVVGQQLNKKQHQQQGIVVQPSNVTASSSLLPKAVHLANLNLVPHSVAASVTAKSSAQRRNQPQVTQMSVPLVHQVKKAAPVIVEAFNKVLHSANPVPIYSPNLSPPPDTSINLPASGYCCLECGDSFALEKSLTQHYSRRSVHIEVMCTQCSTMLLFFNKCSLLKHARDHKSKGFIMQCSQLVMKPISLDQMFSPSASSSASSTPQTLHLSSPSRKPNASSGNGVGISTNTQPAMPLYPDPLRLIRHGLKCLECNKQAQDYVALAAHYQRTSEDSERLTCQVCQMMLPNQCSYCAHQRIHAHKSPYCCPECGAVCRSAYFQTHVKENCLHYSRKVGFRCIHCGVVFMTLALLKVHIHEKHCEVFHKCSFCPMAFKSADSTVAHMTSQHSAEPHKTTQVIYKCSCETVFNKKKLLQEHFEQNTNKLLVGVFKCPQCQLVYMQKQQLMQHVKGVHGVPQNPEELLNFRQKSEKIAKNQVHNTPKELLVANGTSHSPLPRKDMRVEGHNLESKSRLRRTGWTCKECSQWMPDRETYVSHMKRSHGRAMKRYPCRQCERSFNASNSLRRHIRNNHDTAKKVYTCWYCTDENQTFPQPFMLENHISLMHGIKNPDLSQMAKARAPDRDTAEARSPKRMATNELGQAETAAGSDAPPAKKLKAHWKCAKCGFATDISTEFQEHIPQHKTDSSTYQCLFCGLCYTSQISLNRHLFIVHKVKDEEEEEEEEDEEEQEEGEEVREKLRAETNENGHEGYNGEMNTTAEEESLECKECKTDSALCEHRQTCGVEGPRSTSQNNHSKSVKT", "length": 1302, "header": "tr|A0A8V0ZMT9-1|A0A8V0ZMT9_CHICK Isoform 1 of Zinc finger protein 592 OS=Gallus gallus OX=9031 GN=ZNF592 PE=3 SV=1 CANONICAL=A0A8V0ZMT9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9/entry#A0A8V0ZMT9-1", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDPTSLDAKETIPSAGEENENHLKSSGICIDENVSLSHSLPPSDAPVVSVIVKNTSRQESFEAEKEGNHLGTGLLHNGFRGSDLPSEAHALVHNYGKFESTFINGDSSRSYSEKLDQSKSEPLPTFSQFSPISSPEPEDTFKENSIGDKPKHAQTPYFPPPSMYMPTGASVLDHFRKVPEPELSMFDQYCKKEQKMEIHFQPESRQEMSRREQDKATERFVESGKDLVDTNSFLGEGLVFGELPHSNLGEDKGSVPELNLSSSVPPRQRLKPTHSKLSSCVAALVALQAKKVACIPKGDQPNLIKEPGPFKDGTKGSPKMPKSPKSPRSPLEVVRKASKQPESPRSVCSDSSGKGSPSMAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPESDELGKSLEESPLETSSAEEFIKSFPSPDTSAVMESEASKNSTKNGAAIAIQLSNIVSPYTDGLKADLAANTTSLVSLSPLPNCGGGAIKVGVVGQQLNKKQHQQQGIVVQPSNVTASSSLLPKAVHLANLNLVPHSVAASVTAKSSAQRRNQPQVTQMSVPLVHQVKKAAPVIVEAFNKVLHSANPVPIYSPNLSPPPDTSINLPASGYCCLECGDSFALEKSLTQHYSRRSVHIEVMCTQCSTMLLFFNKCSLLKHARDHKSKGFIMQCSQLVMKPISLDQMFSPSASSSASSTPQTLHLSSPSRKPNASSGNGVGISTNTQPAMPLYPDPLRLIRHGLKCLECNKQAQDYVALAAHYQRTSEDSERLTCQVCQMMLPNQCSYCAHQRIHAHKSPYCCPECGAVCRSAYFQTHVKENCLHYSRKVGFRCIHCGVVFMTLALLKVHIHEKHCEVFHKCSFCPMAFKSADSTVAHMTSQHSAEPHKTTQVIYKCSCETVFNKKKLLQEHFEQNTNKLLVGVFKCPQCQLVYMQKQQLMQHVKGVHGVPQNPEELLNFRQKSEKIAKNQVHNTPKELLVANGTSHSPLPRKDMRVEGHNLESKSRLRRTGWTCKECSQWMPDRETYVSHMKRSHGRAMKRYPCRQCERSFNASNSLRRHIRNNHDTAKKVYTCWYCTDENQTFPQPFMLENHISLMHGIKNPDLSQMAKARAPDRDTAEARSPKRMATNELGQAETAAGSDAPPAKKLKAHWKCAKCGFATDISTEFQEHIPQHKTDSSTYQCLFCGLCYTSQISLNRHLFIVHKVKDEEEEEEEEDEEEQEEGEEVREKLRAETNENGHEGYNGEMNTTAEEESLECKECKTDSALCEHRQTCGVEGPRSTSQNNHSKSVKT", "length": 1302, "header": "tr|A0A8V0ZMT9-1|A0A8V0ZMT9_CHICK Isoform 1 of Zinc finger protein 592 OS=Gallus gallus OX=9031 GN=ZNF592 PE=3 SV=1 CANONICAL=A0A8V0ZMT9-1" }, "locus": { "chromosome": "10", "start_pos": 1026686, "end_pos": 998721, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054280.1", "url": "https://www.ensembl.org/id/ENSGALT00010054280.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032777.1", "url": "https://www.ensembl.org/id/ENSGALP00010032777.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415335", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415335", "resource": "KEGG Pathway" }, { "id": "R-GGA-9940951", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940951", "resource": "Reactome", "description": "Interaction of NuRD complexes with transcription factors" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B5T2-1", "protein_name": "Zinc finger protein 592 isoform X1", "gene_name": "znf592", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDATSLDAKEAIHGNQDEGDGHLKHSEMCMDTTVSIPHPVPTADAPAVSVIVKNTSRQNSYENLVEKESPHLGHLLQNGFKSSVGSLETHPSSYPRLDSSSVNGENFNHSLEKTPVLYKPEKGPTLSESVSQFSPISSPESEDIQSNGIDDCPKSAETSYFPSDSLFTSPTVTVLDYLEKADVPDSGCNYSHCGSKGVDDLESDSSSFKDDLVGKNADSATKSDCSQDCRTNTYPTLETNSPSRPCAKAHTSRLSSCIDALAALNPKKDSGGHINSKDIPVTPKETVKISQKIPISPRSPKSPLEVVKRFTKQPDSPMSICSDSSGKASPAVATGSPPAIPRVRIKTIKTSSGEIKRTVTSILPDSETEDLMSPFGSSPSQSSVEEAFSKTLPPNHSTDIISEVIFEDGSQEASKMASSGSTKSVRSSKSPQIQNIGHALKTTEGGTQQRKATSAQIGSSANTNYLPKALHLANLNLVPHSVAASVTARSSTNRQEPSQLSSSMVCSSVPLVHQVKKVSPNTRAVVPNTAAGTLNRLLNYSNPVPTYVPNLSPPPGTNIKLPTQGYCCLECGDSFGLEKSLAYHYSRRSVHIEVACTHCSKTLVFFNRCALLAHARDHKNKGMVMQCTQLFMKPIAVDQMLVPTKTSLQSAIQIPCGNTTTEPSKGQVVLPLYPDNVIRNGSKCLECNKQISDYTALARHYQKSSEDEGLICKVCSMLLPNKCSYRAHQRIHTHKSPYCCPECGALSRSVDIQKHVKENCLHYTRKIGYSCLHCEMLFMSLSHLKSHIEEKHCEVFYKCTTCPVAFKSYDGCLMHVKNKHGGSEPNHQVIYKCSCETVFKRRQLLYQHFHNRICVFKCPECTSLFPEKLPLVQHFKTIHGGVFRGEAEKSSKTTETSLPKNLQPSLTKAGNEACVKEMENSTARKSSAEAGIKNTGWTCGVCLLWVPDRETYVSHMKTSHGKSLKRQPCRLCERSFNSPMSLKRHIRNDHNGKKKVYTCWYCTSERMSFTEHSLLKNHISLMHGVKNPDFSQMAKLESQEVGKIRSERPKKRRAEHPDGVKGNGETSHNTPSKRHKPLYRCAKCGFTSEAQAQFQEHIPQHKSDSNTPQCQHCGLCFTSQLALSRHLFIVHKVKEPEEHEDFKDGKEREISTDLSDKTVPLLRNKTGLSTAEDQLGLHNVPTDTDYNTQTSENSGLEDKKA", "length": 1219 }, "evidence": [ { "id": "A0A8V0ZMT9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMT9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZJG8-1", "protein_name": "Zinc finger protein 592", "gene_name": "Zfp592", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKSSGMCMDENVSLSHSGSVPDVPAVSVIVKNTSRQESFEAEKDHITPSLLHNGFRGSDLPPDSHHCGKFDSTFINGDSARSFTSKLEPSKSEPLPTFNQFSPISSPEPEDPVKDNGFGIKSKHSDSYFPPPPGTVGGPVLEALAKFPVPELHMFDHFCKKEPKPEPLPLESQQEHEQGGQKVVEPHKDLDSSRFFGEALEFNSHPSNSIGEPKKLVPELSACSSVPPRQRLKPAHSKLSSCVAALVALQAKRVANVTKEDQPGHIKDSSGPTKEGSKGSPKMPKSPKSPRSPLEATRKNIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRVLPDPDDPSESPAGGTSAEVPSEVPGDEGSAMPVEEHFSEAGIDSGSPQGDRKGGENMINKTSDSLSPCRTSGPRVPKGSALNSQASKKQQSTALQASTPAPASLLPKAVHLANLNLVPHSVAASVTAKSSAQRRSQPQVTQMTVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYSRRSVHIEVLCTLCSKTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVAAPVNSTAPATPAASSSPKPSPTLDNASPVIPALPLYPDPVRLIRYGTKCPECHKQMRDYMVLATHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKVGYRCIHCGVIHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTMDHSTTQHPTQPHKPSQLIYKCSCEMIFNKKRHIQQHFYQNVSKTQAAVFKCPECPLLFLQKPELMQHVKNTHGVPRNVEELSSLQSSTDTSSNRPGSRAPTEPPATNVATRGSSLTAGRWGRPDAHRRAEARPRMRNTGWTCQECQEWVPDRESYVSHMKKSHGRTLRRYPCRQCEQSFHNPSSLRKHIRNNHDTVKKVYTCGYCSEDSPSFPRPSLLESHISLMHGIRNPDLSQTSKVKHAGGHSPQVNHLKRPVSRMADAPGTSNGATASSTKRHKPLFQCARCTFSTDSELEFQSHIPQHQVDSSTAQCPLCGLCYTSARSLSRHLFIVHKVRGQEEGGEEIVQVKVEATDPEACSGEEVAVKTGENGLEECVSEPLVADIEPRRSLGLAVDEDSAQDPQNQPQASQDQNSHALSPQV", "length": 1262 }, "evidence": [ { "id": "A0A8V0ZMT9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMT9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N5U2-1", "protein_name": "Zinc finger protein 592", "gene_name": "ZNF592", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKPPGLCVDENVSLSHSGSASDVPAVSVIVKNTSRQESFEAEKDHIAPSLLHNGFRGSDLPADPHSLGHNCGKFDSTFMNGDSTRGFPGKLEASKSEPLPTFNQFSPISSPEPEDAIKDNGFGMKPKHSDSYFPPPPGCGSVGGPVLEALTKFPVPELHMFDHFCKKEPKPEPLPLGSPQEHERGGQKALEVHKELDASRFFGDALDFSSHPGNSIGEPKGLASELGTGSAFPPRQRLKPAHSKLSSCVAALVALQAKRVANVAKEDQTSHTKDPSGPAKEGSKGSPKMPKSPKSPRSPLEATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDPDDPSKSPSGSPLGSATAEAPSEAPEDEATTLSGVEHFAEVGAQPGSPQSDRKGEECTAKASEPSPSCFSSGARGQKGAASGTLEGRKPQQSPAPPASAPAPANLLPKAVHLANLNLVPHSVAASVTAKSSVQRRSQPQPTQMSVPLVHQVKKAAPLVLEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSQTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVSTPANSTAPAAAAPPSPSQPGQASSNASTPLPALPLYPDPVRLIRHSIKCLECHKQMRDYMAMAAHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGALCRSAYFQTHVKENCLHYARKVGYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQPHRPSQLIYKCSCEMVFNKKRHIQQHFYQNASTAQVGVFKCPECPLLFLQKPELMQHVKSTHGVPRNVDELSSLQSSADSSSSRPGPRVPAEPPALSVTARGSALPSSRWGRPEAHRRAEARPRLRNTGWTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHTPNSLRKHIRNNHDTVKKVYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLSQTSKARPSGGHSPQVNHLKRPVSGVGAAPDTSNGTPVSSTKRHKSLFQCAKCSFATDSGLEFQRHIPQHQKDSSTAQCLLCGLCYTSAGSLSRHLFIVHKVRDQEEEEAEAAEPEEGSGEEVPMETRENGLEESAEEPLVGDSETGRSLGLAQDEDGAQDAPSRPQTSQDRDSHTPSPQV", "length": 1265 }, "evidence": [ { "id": "A0A8V0ZMT9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMT9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BHZ4-1", "protein_name": "Zinc finger protein 592", "gene_name": "Znf592", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQAPSEENESPLKSSGMCIDENVSLSHSGSAPDVPAVSVIVKNTSRQESFEAEKDHIAPSLLHNGFRGSDLPPDSHHCGKFDSTFINGDSARSFTSKLEPSKSEPLPTFNQFSPISSPEPEDPVKDNGFGIKSKHSDSYFPPPPGTVGGPVLEALSKFPVPELHMFDHFCKKEPKPEPLPLESQQEHEQGGQKVVEPHKDLDSSRFFGEALEFNSHPSNSIGEPKKLAPELSACSSVPPRQRLKPAHSKLSSCVAALVALQAKRVANVTKEDQPGHTKDSSGPTKEGSKGSPKMPKSPKSPRSPLEATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDPDDPSKSPAESPAGSTITEAPSEAPGDEGTAMPVEEHFSEAGIHSGSPQGDRKGDENMIKTSDSSSPCRISGSRVPKGSALNSQASKKQQSTAPQASTPAASLLPKAVHLANLNLVPHSVAASVTAKSSAQRRSQPQVTQMTVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYSRRSVHIEVLCTLCSKTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVAAPVNSTAPATPAASSSPKPSPTLDNASSVIPALPLYPDPVRLIRYGTKCPECHKQMRDYMVLATHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKVGYRCIHCGVIHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTMDHSTTQHPTQPHKPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKTQAGVFKCPECPLLFLQKPELMQHVKNTHGVPRNVEELSSLQSSTDTSSNRPGSRAPAEPPATNVAARGSSLTAGRWGRPEAHRRAEARPRMRSTGWTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHNPSSLRKHIRNNHDTVKKVYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLSQTSKVRHPGGPSPQVNHLKRPVSRMADAPGTSNGATVSSTKRHKSLFQCAKCTFATDSELEFQSHIPQHQVDSSTAQCLLCGLCYTSTSSLNRHLFIVHKVRDQEEGGEDIVEVKVEAPDSEACSGEEVAMETKENGLEECASEPLVTDLGGQQGLALDEDSAQDPQNQPQASQDQNSHALSPQV", "length": 1262 }, "evidence": [ { "id": "A0A8V0ZMT9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMT9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92610-1", "protein_name": "Zinc finger protein 592", "gene_name": "ZNF592", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDMKTPDFDDLLAAFDIPDPTSLDAKEAIQTPSEENESPLKPPGICMDESVSLSHSGSAPDVPAVSVIVKNTSRQESFEAEKDHITPSLLHNGFRGSDLPPDPHNCGKFDSTFMNGDSARSFPGKLEPPKSEPLPTFNQFSPISSPEPEDPIKDNGFGIKPKHSDSYFPPPLGCGAVGGPVLEALAKFPVPELHMFDHFCKKEPKPEPLPLGSQQEHEQSGQNTVEPHKDPDATRFFGEALEFNSHPSNSIGESKGLARELGTCSSVPPRQRLKPAHSKLSSCVAALVALQAKRVASVTKEDQPGHTKDLSGPTKESSKGSPKMPKSPKSPRSPLEATRKSIKPSDSPRSICSDSSSKGSPSVAASSPPAIPKVRIKTIKTSSGEIKRTVTRILPDPDDPSKSPVGSPLGSAIAEAPSEMPGDEVPVEEHFPEAGTNSGSPQGARKGDESMTKASDSSSPSCSSGPRVPKGAAPGSQTGKKQQSTALQASTLAPANLLPKAVHLANLNLVPHSVAASVTAKSSVQRRSQPQLTQMSVPLVHQVKKAAPLIVEVFNKVLHSSNPVPLYAPNLSPPADSRIHVPASGYCCLECGDAFALEKSLSQHYGRRSVHIEVLCTLCSKTLLFFNKCSLLRHARDHKSKGLVMQCSQLLVKPISADQMFVSAPVNSTAPAAPAPSSSPKHGLTSGSASPPPPALPLYPDPVRLIRYSIKCLECHKQMRDYMVLAAHFQRTTEETEGLTCQVCQMLLPNQCSFCAHQRIHAHKSPYCCPECGVLCRSAYFQTHVKENCLHYARKVGYRCIHCGVVHLTLALLKSHIQERHCQVFHKCAFCPMAFKTASSTADHSATQHPTQPHRPSQLIYKCSCEMVFNKKRHIQQHFYQNVSKTQVGVFKCPECPLLFVQKPELMQHVKSTHGVPRNVDELSSLQSSADTSSSRPGSRVPTEPPATSVAARSSSLPSGRWGRPEAHRRVEARPRLRNTGWTCQECQEWVPDRESYVSHMKKSHGRTLKRYPCRQCEQSFHTPNSLRKHIRNNHDTVKKFYTCGYCTEDSPSFPRPSLLESHISLMHGIRNPDLSQTSKVKPPGGHSPQVNHLKRPVSGVGDAPGTSNGATVSSTKRHKSLFQCAKCSFATDSGLEFQSHIPQHQVDSSTAQCLLCGLCYTSASSLSRHLFIVHKVRDQEEEEEEEAAAAEMAVEVAEPEEGSGEEVPMETRENGLEECAGEPLSADPEARRLLGPAPEDDGGHNDHSQPQASQDQDSHTLSPQV", "length": 1267 }, "evidence": [ { "id": "A0A8V0ZMT9", "url": "https://omabrowser.org/oma/group/A0A8V0ZMT9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1060, "end_pos": 1062, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1089, "end_pos": 1091, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1257, "end_pos": 1259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1295, "end_pos": 1297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 990, "end_pos": 992, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZMT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMT9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 620, "end_pos": 645, "start_aa": "Tyr", 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"uniprot_id": "A0A8V0ZMU3_CHICK", "mass": { "chemical_mass": 54923.0, "monoisotopic_mass": 54923.0 }, "refseq": {}, "gene_names": [ { "name": "OLFM3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZMU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU3" } ] } ], "protein_names": [ { "name": "Olfactomedin 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZMU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OLFM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU3", "locus": { "chromosome": "8", "start_pos": 11262125, "end_pos": 11206213, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023421", "url": "https://www.ensembl.org/id/ENSGALG00010023421" } ] } } ], "crossref": [ { "id": "A0A8V0ZMU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZMU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMU3", "url": "https://www.orthodb.org/?gene=A0A8V0ZMU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMU7", "url": "https://www.orthodb.org/?gene=A0A8V0ZMU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMV2", "url": "https://www.orthodb.org/?gene=A0A8V0ZMV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT26", "url": "https://www.orthodb.org/?gene=A0A8V0ZT26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT31", "url": "https://www.orthodb.org/?gene=A0A8V0ZT31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12308", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12308", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZMU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPPLLKLGAVLSTMAMISNWMSQTLPSLVGLNTTRLPNSDTLTQISPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTDAKLITQFKEEIRNLSTVLTGIQEEIGAYDYDELHQRVLSLETRLRDCMKKLTCGKLMKITGPITVKISGTRFGAWMTDPLASEKNNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDTGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDTLEVLKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFHVIKTEDDT", "length": 478, "header": "tr|A0A8V0ZMU3-1|A0A8V0ZMU3_CHICK Isoform 1 of Olfactomedin 3 OS=Gallus gallus OX=9031 GN=OLFM3 PE=1 SV=1 CANONICAL=A0A8V0ZMU3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU3/entry#A0A8V0ZMU3-1", "sequence": { "sequence": "MSPPLLKLGAVLSTMAMISNWMSQTLPSLVGLNTTRLPNSDTLTQISPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTDAKLITQFKEEIRNLSTVLTGIQEEIGAYDYDELHQRVLSLETRLRDCMKKLTCGKLMKITGPITVKISGTRFGAWMTDPLASEKNNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDTGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDTLEVLKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFHVIKTEDDT", "length": 478, "header": "tr|A0A8V0ZMU3-1|A0A8V0ZMU3_CHICK Isoform 1 of Olfactomedin 3 OS=Gallus gallus OX=9031 GN=OLFM3 PE=1 SV=1 CANONICAL=A0A8V0ZMU3-1" }, "locus": { "chromosome": "8", "start_pos": 11260167, "end_pos": 11243077, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057077.1", "url": "https://www.ensembl.org/id/ENSGALT00010057077.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034716.1", "url": "https://www.ensembl.org/id/ENSGALP00010034716.1" } ] } }, { "isoform_ac": "A0A8V0ZMU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU3/entry#A0A8V0ZMU7-1", "sequence": { "sequence": "MASGVQRVLERPFIHLETQISPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTDAKLITQFKEEIRNLSTVLTGIQEEIGAYDYDELHQRVLSLETRLRDCMKKLTCGKLMKITGPITVKISGTRFGAWMTDPLASEKNNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDTGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDTLEVLKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFHVIKTEDDT", "length": 452, "header": "tr|A0A8V0ZMU7-1|A0A8V0ZMU7_CHICK Computationally mapped isoform of Olfactomedin 3 OS=Gallus gallus OX=9031 GN=OLFM3 PE=1 SV=1 CANONICAL=A0A8V0ZMU3-1" }, "locus": { "chromosome": "8", "start_pos": 11260167, "end_pos": 11208012, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057084.1", "url": "https://www.ensembl.org/id/ENSGALT00010057084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034721.1", "url": "https://www.ensembl.org/id/ENSGALP00010034721.1" } ] } }, { "isoform_ac": "A0A8V0ZMV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU3/entry#A0A8V0ZMV2-1", "sequence": { "sequence": "MPARFSPTWRSGFCLRWGLKGKAKKKNKGKKKTQISPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTDAKLITQFKEEIRNLSTVLTGIQEEIGAYDYDELHQRVLSLETRLRDCMKKLTCGKLMKITGPITVKISGTRFGAWMTDPLASEKNNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDTGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDTLEVLKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFHVIKTEDDT", "length": 467, "header": "tr|A0A8V0ZMV2-1|A0A8V0ZMV2_CHICK Computationally mapped isoform of Olfactomedin 3 OS=Gallus gallus OX=9031 GN=OLFM3 PE=1 SV=1 CANONICAL=A0A8V0ZMU3-1" }, "locus": { "chromosome": "8", "start_pos": 11260167, "end_pos": 11245380, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057091.1", "url": "https://www.ensembl.org/id/ENSGALT00010057091.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034726.1", "url": "https://www.ensembl.org/id/ENSGALP00010034726.1" } ] } }, { "isoform_ac": "A0A8V0ZT26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU3/entry#A0A8V0ZT26-1", "sequence": { "sequence": "MKIFLSMFQNITLQTQISPKEGWQVYSSAQDPDGRCICTVVAPEQNLCSRDAKSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQYKTDAKLITQFKEEIRNLSTVLTGIQEEIGAYDYDELHQRVLSLETRLRDCMKKLTCGKLMKITGPITVKISGTRFGAWMTDPLASEKNNRVWYMDSYTNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSLYFNKYQSNIIIKYSFDTGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYATNQNAGNIVISQLNQDTLEVLKSWSTGYPKRSAGESFMICGTLYVTNSHLTGAKVYYSYSTKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTLFHVIKTEDDT", "length": 449, "header": "tr|A0A8V0ZT26-1|A0A8V0ZMU3_CHICK Computationally mapped isoform of Olfactomedin 3 OS=Gallus gallus OX=9031 GN=OLFM3 PE=1 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"header": "tr|A0A8V0ZT31-1|A0A8V0ZMU3_CHICK Computationally mapped isoform of Olfactomedin 3 OS=Gallus gallus OX=9031 GN=OLFM3 PE=1 SV=1 CANONICAL=A0A8V0ZMU3-1" }, "locus": { "chromosome": "8", "start_pos": 11260167, "end_pos": 11206402, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057087.1", "url": "https://www.ensembl.org/id/ENSGALT00010057087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034723.1", "url": "https://www.ensembl.org/id/ENSGALP00010034723.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMU3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU3" } ], "pmid": "" }, { "name": 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This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon. 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"end_pos": 2424671, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057128.1", "url": "https://www.ensembl.org/id/ENSGALT00010057128.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034751.1", "url": "https://www.ensembl.org/id/ENSGALP00010034751.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": 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"MTPNYWCPLMRMMKSSLHSEEDDFVPELQRSIHPRERPDWEETLSAMARGADIPDITGELPLRTCSSTASMKVKNVKKYINPGLMGCDAFHRLSFTKGHFPKMAECAHFHYENVDFGNIQLSLPEEQSEVMRNGCESKELVYLVQISCQGKSWIVKRSYEDFRVLDKHLHLCIYDRRFSQLAELPRSDVLRDSPELVTHTLMAYLSRLSAIACNKINCGPALTWMEIDNKGNHLLVHEESSINIPAIAAAHVIKRYIAQAPDELSFEVGDIVSVIDMPPKELTTWWRGKHGFQVGFFPSECVELINDKVPQSVTNSVPKPVSKKHGKLITFLRSFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGQDVPQVLKSCTEFIEKHGIVDGIYRLSGVASNIQKLRHEFDSEQIPDLTKDNYIHDIHSVSSLCKMYFRELPNPLLTYQLYEKFSDAVSAATDEERLVRIHDVIQQLPPPHYRTLEYLMRHLARLADYCTITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHTDVLFSSKFSSVIRDGAGHSSLSRPKSLLVSSPSTKLLTLEEAQARTQGQINSPMVTDNRYIEVGEGPAALQGKFHTVIDFPSERKRPPNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNPSEPSEMKVIALAGGRGDSGTLRSAKSEESLTSLHAVDGESNRFRPRRPRSSSDALSASFNGELLGGMNRCNSYDNLPHDNSDGDKELIHVPALISPRSAEDVDLSPPDIGVASLDFDPMSFQCSPPQAESECPDSSTSMLESIGISKEKPSLLKKDLESGSQSQTPGSATSSEPVSPFQEKMSPFFTLDLSPTEEKTFKPSDTSPQMGKKPIKSPPLTTSEPVSFALPSCTSESIGGMLITTRNSSTSNWNEEIGITEITNRFPTQMSLPLKEIERAPEEEAHQELKHAQIVAAGKPELPEEGERPMSSSQNKTVPSGHAQPGAVALDSPQDPVPVSSVSLIPPPPPKNAARMLALALAESAQQASAQSQKKPGDAHSESTSYGETEAATALEKLHLSAGAPDKLHLYTDLPENQLHFQTSAPVEQDFQASSTAREQNHPPGAPGSQDPQPLHTSVPGDVPARRDAEQEQSSYLAGQTENKEQFPAHAEDWEQTRQHAPGALPDWEPPTTNLPMDKPHVRACTSGDKQLTSTCAADDKLETPVTAGEKSTPVPVPYLTTIQTAAAEPTRAPTCQHAAGPAIIQADVTGTSAQRTPTGSQPAPPQRQDHQSAVGQVPAASAKASSNSSQVWGAAAPEKPPEPAPGFATESTSSTHRSSSVPSGHQSRLEKPREGTRAPMLHLRSESVPTHSSYSFTPPVPPVRTLESKIAAAMHSNNADAINNSNYHAFLASSMLASSVEEVLLPPPAPPPPPLPPPPLAPPPPPPPPPKHSSLQSVYVPHPKPESILEPSGPDVYLHHKPTSIHQYRPESVPPHMTYHSKPDQHPAYPPRSETPTSAGSRYNTYTNQGRSTSAVYSKPRSRLEFVSSVSPTGLRNAAYGEDPPPYPTIRRVQSLHVPTPAASTIRSVPISRTEVPPDDEPLFCPRPLYQYKPYQPHSDYHVTQLQPYFENGRVHYRYSPYSSSSGSSYYTSADGNFYDLDPYSTMRVRPFHPLHSRDFASYEARLHSKGLYRYPGLSAYPRGGLIGHLAGKEHSFISRDVPPAPDIKHMYMSWDLEDMEKYRMQSIRRESRTRQKMKGPLMSQYDNVTPLLPEDPGGPDIIHLRSKSDPGKSGLLTVAEGKEGKYPAKAATPDGDERYYMQHPEPELDRAHYHGAYGNGQPEKPSLPQKQSSIRSRKMHEPTCSASDHRPHLQQEPSHRQPSEPKNGPPYPDYRPKGPEPAEPMGYQHLGRKYFLANQDTLRLNHKEARLAEDRPDLERSRARPSTSVEKHSRDGYKEEEHAASPMAPPPSPERSHSLRVQHRESVEKDSALFYPYQTLGKRQSTMTVMSQYDNVEDYHTMPQHQRGGYAGEGGCVPPTFTHVHSRIYATALGQGAFLPTELCLQRPETEVHVE", "length": 2063, "header": "tr|A0A8V0ZMZ0-1|A0A8V0ZMZ0_CHICK Isoform 1 of Rho GTPase-activating protein 32 OS=Gallus gallus OX=9031 GN=ARHGAP33 PE=3 SV=1 CANONICAL=A0A8V0ZMZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZMY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0/entry#A0A8V0ZMY2-1", "sequence": { "sequence": "MARGADIPDITGELPLRTCSSTASMKVKNVKKYINPGLMGCDAFHRLSFTKGHFPKMAECAHFHYENVDFGNIQLSLPEEQSEVMRNGCESKELVYLVQISCQGKSWIVKRSYEDFRVLDKHLHLCIYDRRFSQLAELPRSDVLRDSPELVTHTLMAYLSRLSAIACNKINCGPALTWMEIDNKGNHLLVHEESSINIPAIAAAHVIKRYIAQAPDELSFEVGDIVSVIDMPPKELTTWWRGKHGFQVGFFPSECVELINDKVPQSVTNSVPKPVSKKHGKLITFLRSFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGQDVPQVLKSCTEFIEKHGIVDGIYRLSGVASNIQKLRHEFDSEQIPDLTKDNYIHDIHSVSSLCKMYFRELPNPLLTYQLYEKFSDAVSAATDEERLVRIHDVIQQLPPPHYRTLEYLMRHLARLADYCTITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHTDVLFSSKFSSVIRDGAGHSSLSRPKSLLVSSPSTKLLTLEEAQARTQGQINSPMVTDNRYIEVGEGPAALQGKFHTVIDFPSERKRPPNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNPSEPSEMKVIALAGGRGDSGTLRSAKSEESLTSLHAVDGESNRFRPRRPRSSSDALSASFNGELLGGMNRCNSYDNLPHDNSDGDKELIHVPALISPRSAEDVDLSPPDIGVASLDFDPMSFQCSPPQAESECPDSSTSMLESIGISKEKPSLLKKDLESGSQSQTPGSATSSEPVSPFQEKMSPFFTLDLSPTEEKTFKPSDTSPQMGKKPIKSPPLTTSEPVSFALPSCTSESIGGMLITTRNSSTSNWNEEIGITEITNRFPTQMSLPLKEIERAPEEEAHQELKHAQIVAAGKPELPEEGERPMSSSQNKTVPSGHAQPGAVALDSPQDPVPVSSVSLIPPPPPKNAARMLALALAESAQQASAQSQKKPGDAHSESTSYGETEAATALEKLHLSAGAPDKLHLYTDLPENQLHFQTSAPVEQDFQASSTAREQNHPPGAPGSQDPQPLHTSVPGDVPARRDAEQEQSSYLAGQTENKEQFPAHAEDWEQTRQHAPGALPDWEPPTTNLPMDKPHVRACTSGDKQLTSTCAADDKLETPVTAGEKSTPVPVPYLTTIQTAAAEPTRAPTCQHAAGPAIIQADVTGTSAQRTPTGSQPAPPQRQDHQSAVGQVPAASAKASSNSSQVWGAAAPEKPPEPAPGFATESTSSTHRSSSVPSGHQSRLEKPREGTRAPMLHLRSESVPTHSSYSFTPPVPPVRTLESKIAAAMHSNNADAINNSNYHAFLASSMLASSVEEVLLPPPAPPPPPLPPPPLAPPPPPPPPPKHSSLQSVYVPHPKPESILEPSGPDVYLHHKPTSIHQYRPESVPPHMTYHSKPDQHPAYPPRSETPTSAGSRYNTYTNQGRSTSAVYSKPRSRLEFVSSVSPTGLRNAAYGEDPPPYPTIRRVQSLHVPTPAASTIRSVPISRTEVPPDDEPLFCPRPLYQYKPYQPHSDYHVTQLQPYFENGRVHYRYSPYSSSSGSSYYTSADGNFYDLDPYSTMRVRPFHPLHSRDFASYEARLHSKGLYRYPGLSAYPRGGLIGHLAGKEHSFISRDVPPAPDIKHMYMSWDLEDMEKYRMQSIRRESRTRQKMKGPLMSQYDNVTPLLPEDPGGPDIIHLRSKSDPGKSGLLTVAEGKEGKYPAKAATPDGDERYYMQHPEPELDRAHYHGAYGNGQPEKPSLPQKQSSIRSRKMHEPTCSASDHRPHLQQEPSHRQPSEPKNGPPYPDYRPKGPEPAEPMGYQHLGRKYFLANQDTLRLNHKEARLAEDRPDLERSRARPSTSVEKHSRDGYKEEEHAASPMAPPPSPERSHSLRVQHRESVEKDSALFYPYQTLGKRQSTMTVMSQYDNVEDYHTMPQHQRGGYAGEGGCVPPTFTHVHSRIYATALGQGAFLPTELCLQRPETEVHVE", "length": 2017, "header": "tr|A0A8V0ZMY2-1|A0A8V0ZMZ0_CHICK Computationally mapped isoform of Rho GTPase-activating protein 32 OS=Gallus gallus OX=9031 GN=ARHGAP33 PE=3 SV=1 CANONICAL=A0A8V0ZMZ0-1" }, "locus": { "chromosome": "24", "start_pos": 1302144, "end_pos": 1204892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057147.1", "url": "https://www.ensembl.org/id/ENSGALT00010057147.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034761.1", "url": "https://www.ensembl.org/id/ENSGALP00010034761.1" } ] } }, { "isoform_ac": "A0A8V0ZMZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0/entry#A0A8V0ZMZ0-1", "sequence": { "sequence": "MTPNYWCPLMRMMKSSLHSEEDDFVPELQRSIHPRERPDWEETLSAMARGADIPDITGELPLRTCSSTASMKVKNVKKYINPGLMGCDAFHRLSFTKGHFPKMAECAHFHYENVDFGNIQLSLPEEQSEVMRNGCESKELVYLVQISCQGKSWIVKRSYEDFRVLDKHLHLCIYDRRFSQLAELPRSDVLRDSPELVTHTLMAYLSRLSAIACNKINCGPALTWMEIDNKGNHLLVHEESSINIPAIAAAHVIKRYIAQAPDELSFEVGDIVSVIDMPPKELTTWWRGKHGFQVGFFPSECVELINDKVPQSVTNSVPKPVSKKHGKLITFLRSFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGQDVPQVLKSCTEFIEKHGIVDGIYRLSGVASNIQKLRHEFDSEQIPDLTKDNYIHDIHSVSSLCKMYFRELPNPLLTYQLYEKFSDAVSAATDEERLVRIHDVIQQLPPPHYRTLEYLMRHLARLADYCTITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHTDVLFSSKFSSVIRDGAGHSSLSRPKSLLVSSPSTKLLTLEEAQARTQGQINSPMVTDNRYIEVGEGPAALQGKFHTVIDFPSERKRPPNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNPSEPSEMKVIALAGGRGDSGTLRSAKSEESLTSLHAVDGESNRFRPRRPRSSSDALSASFNGELLGGMNRCNSYDNLPHDNSDGDKELIHVPALISPRSAEDVDLSPPDIGVASLDFDPMSFQCSPPQAESECPDSSTSMLESIGISKEKPSLLKKDLESGSQSQTPGSATSSEPVSPFQEKMSPFFTLDLSPTEEKTFKPSDTSPQMGKKPIKSPPLTTSEPVSFALPSCTSESIGGMLITTRNSSTSNWNEEIGITEITNRFPTQMSLPLKEIERAPEEEAHQELKHAQIVAAGKPELPEEGERPMSSSQNKTVPSGHAQPGAVALDSPQDPVPVSSVSLIPPPPPKNAARMLALALAESAQQASAQSQKKPGDAHSESTSYGETEAATALEKLHLSAGAPDKLHLYTDLPENQLHFQTSAPVEQDFQASSTAREQNHPPGAPGSQDPQPLHTSVPGDVPARRDAEQEQSSYLAGQTENKEQFPAHAEDWEQTRQHAPGALPDWEPPTTNLPMDKPHVRACTSGDKQLTSTCAADDKLETPVTAGEKSTPVPVPYLTTIQTAAAEPTRAPTCQHAAGPAIIQADVTGTSAQRTPTGSQPAPPQRQDHQSAVGQVPAASAKASSNSSQVWGAAAPEKPPEPAPGFATESTSSTHRSSSVPSGHQSRLEKPREGTRAPMLHLRSESVPTHSSYSFTPPVPPVRTLESKIAAAMHSNNADAINNSNYHAFLASSMLASSVEEVLLPPPAPPPPPLPPPPLAPPPPPPPPPKHSSLQSVYVPHPKPESILEPSGPDVYLHHKPTSIHQYRPESVPPHMTYHSKPDQHPAYPPRSETPTSAGSRYNTYTNQGRSTSAVYSKPRSRLEFVSSVSPTGLRNAAYGEDPPPYPTIRRVQSLHVPTPAASTIRSVPISRTEVPPDDEPLFCPRPLYQYKPYQPHSDYHVTQLQPYFENGRVHYRYSPYSSSSGSSYYTSADGNFYDLDPYSTMRVRPFHPLHSRDFASYEARLHSKGLYRYPGLSAYPRGGLIGHLAGKEHSFISRDVPPAPDIKHMYMSWDLEDMEKYRMQSIRRESRTRQKMKGPLMSQYDNVTPLLPEDPGGPDIIHLRSKSDPGKSGLLTVAEGKEGKYPAKAATPDGDERYYMQHPEPELDRAHYHGAYGNGQPEKPSLPQKQSSIRSRKMHEPTCSASDHRPHLQQEPSHRQPSEPKNGPPYPDYRPKGPEPAEPMGYQHLGRKYFLANQDTLRLNHKEARLAEDRPDLERSRARPSTSVEKHSRDGYKEEEHAASPMAPPPSPERSHSLRVQHRESVEKDSALFYPYQTLGKRQSTMTVMSQYDNVEDYHTMPQHQRGGYAGEGGCVPPTFTHVHSRIYATALGQGAFLPTELCLQRPETEVHVE", "length": 2063, "header": "tr|A0A8V0ZMZ0-1|A0A8V0ZMZ0_CHICK Isoform 1 of Rho GTPase-activating protein 32 OS=Gallus gallus OX=9031 GN=ARHGAP33 PE=3 SV=1 CANONICAL=A0A8V0ZMZ0-1" }, "locus": { "chromosome": "24", "start_pos": 1332342, "end_pos": 1204892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057157.1", "url": "https://www.ensembl.org/id/ENSGALT00010057157.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034766.1", "url": "https://www.ensembl.org/id/ENSGALP00010034766.1" } ] } }, { "isoform_ac": "A0A8V0ZT66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0/entry#A0A8V0ZT66-1", "sequence": { "sequence": "MVPYLHGRMMKSSLHSEEDDFVPELQRSIHPRERPDWEETLSAMARGADIPDITGELPLRTCSSTASMKVKNVKKYINPGLMGCDAFHRLSFTKGHFPKMAECAHFHYENVDFGNIQLSLPEEQSEVMRNGCESKELVYLVQISCQGKSWIVKRSYEDFRVLDKHLHLCIYDRRFSQLAELPRSDVLRDSPELVTHTLMAYLSRLSAIACNKINCGPALTWMEIDNKGNHLLVHEESSINIPAIAAAHVIKRYIAQAPDELSFEVGDIVSVIDMPPKELTTWWRGKHGFQVGFFPSECVELINDKVPQSVTNSVPKPVSKKHGKLITFLRSFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGQDVPQVLKSCTEFIEKHGIVDGIYRLSGVASNIQKLRHEFDSEQIPDLTKDNYIHDIHSVSSLCKMYFRELPNPLLTYQLYEKFSDAVSAATDEERLVRIHDVIQQLPPPHYRTLEYLMRHLARLADYCTITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHTDVLFSSKFSSVIRDGAGHSSLSRPKSLLVSSPSTKLLTLEEAQARTQGQINSPMVTDNRYIEVGEGPAALQGKFHTVIDFPSERKRPPNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNPSEPSEMKVIALAGGRGDSGTLRSAKSEESLTSLHAVDGESNRFRPRRPRSSSDALSASFNGELLGGMNRCNSYDNLPHDNSDGDKELIHVPALISPRSAEDVDLSPPDIGVASLDFDPMSFQCSPPQAESECPDSSTSMLESIGISKEKPSLLKKDLESGSQSQTPGSATSSEPVSPFQEKMSPFFTLDLSPTEEKTFKPSDTSPQMGKKPIKSPPLTTSEPVSFALPSCTSESIGGMLITTRNSSTSNWNEEIGITEITNRFPTQMSLPLKEIERAPEEEAHQELKHAQIVAAGKPELPEEGERPMSSSQNKTVPSGHAQPGAVALDSPQDPVPVSSVSLIPPPPPKNAARMLALALAESAQQASAQSQKKPGDAHSESTSYGETEAATALEKLHLSAGAPDKLHLYTDLPENQLHFQTSAPVEQDFQASSTAREQNHPPGAPGSQDPQPLHTSVPGDVPARRDAEQEQSSYLAGQTENKEQFPAHAEDWEQTRQHAPGALPDWEPPTTNLPMDKPHVRACTSGDKQLTSTCAADDKLETPVTAGEKSTPVPVPYLTTIQTAAAEPTRAPTCQHAAGPAIIQADVTGTSAQRTPTGSQPAPPQRQDHQSAVGQVPAASAKASSNSSQVWGAAAPEKPPEPAPGFATESTSSTHRSSSVPSGHQSRLEKPREGTRAPMLHLRSESVPTHSSYSFTPPVPPVRTLESKIAAAMHSNNADAINNSNYHAFLASSMLASSVEEVLLPPPAPPPPPLPPPPLAPPPPPPPPPKHSSLQSVYVPHPKPESILEPSGPDVYLHHKPTSIHQYRPESVPPHMTYHSKPDQHPAYPPRSETPTSAGSRYNTYTNQGRSTSAVYSKPRSRLEFVSSVSPTGLRNAAYGEDPPPYPTIRRVQSLHVPTPAASTIRSVPISRTEVPPDDEPLFCPRPLYQYKPYQPHSDYHVTQLQPYFENGRVHYRYSPYSSSSGSSYYTSADGNFYDLDPYSTMRVRPFHPLHSRDFASYEARLHSKGLYRYPGLSAYPRGGLIGHLAGKEHSFISRDVPPAPDIKHMYMSWDLEDMEKYRMQSIRRESRTRQKMKGPLMSQYDNVTPLLPEDPGGPDIIHLRSKSDPGKSGLLTVAEGKEGKYPAKAATPDGDERYYMQHPEPELDRAHYHGAYGNGQPEKPSLPQKQSSIRSRKMHEPTCSASDHRPHLQQEPSHRQPSEPKNGPPYPDYRPKGPEPAEPMGYQHLGRKYFLANQDTLRLNHKEARLAEDRPDLERSRARPSTSVEKHSRDGYKEEEHAASPMAPPPSPERSHSLRVQHRESVEKDSALFYPYQTLGKRQSTMTVMSQYDNVEDYHTMPQHQRGGYAGEGGCVPPTFTHVHSRIYATALGQGAFLPTELCLQRPETEVHVE", "length": 2060, "header": "tr|A0A8V0ZT66-1|A0A8V0ZMZ0_CHICK Computationally mapped isoform of Rho GTPase-activating protein 32 OS=Gallus gallus OX=9031 GN=ARHGAP33 PE=3 SV=1 CANONICAL=A0A8V0ZMZ0-1" }, "locus": { "chromosome": "24", "start_pos": 1326844, "end_pos": 1204892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057152.1", "url": "https://www.ensembl.org/id/ENSGALT00010057152.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034763.1", "url": "https://www.ensembl.org/id/ENSGALP00010034763.1" } ] } }, { "isoform_ac": "A0A8V1A0R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0/entry#A0A8V1A0R7-1", "sequence": { "sequence": "MMKSSLHSEEDDFVPELQRSIHPRERPDWEETLSAMARGADIPDITGELPLRTCSSTASMKVKNVKKLSFTKGHFPKMAECAHFHYENVDFGNIQLSLPEEQSEVMRNGCESKELVYLVQISCQGKSWIVKRSYEDFRVLDKHLHLCIYDRRFSQLAELPRSDVLRDSPELVTHTLMAYLSRLSAIACNKINCGPALTWMEIDNKGNHLLVHEESSINIPAIAAAHVIKRYIAQAPDELSFEVGDIVSVIDMPPKELTTWWRGKHGFQVGFFPSECVELINDKVPQSVTNSVPKPVSKKHGKLITFLRSFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGQDVPQVLKSCTEFIEKHGIVDGIYRLSGVASNIQKLRHEFDSEQIPDLTKDNYIHDIHSVSSLCKMYFRELPNPLLTYQLYEKFSDAVSAATDEERLVRIHDVIQQLPPPHYRTLEYLMRHLARLADYCTITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILNHTDVLFSSKFSSVIRDGAGHSSLSRPKSLLVSSPSTKLLTLEEAQARTQGQINSPMVTDNRYIEVGEGPAALQGKFHTVIDFPSERKRPPNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNPSEPSEMKVIALAGGRGDSGTLRSAKSEESLTSLHAVDGESNRFRPRRPRSSSDALSASFNGELLGGMNRCNSYDNLPHDNSDGDKELIHVPALISPRSAEDVDLSPPDIGVASLDFDPMSFQCSPPQAESECPDSSTSMLESIGISKEKPSLLKKDLESGSQSQTPGSATSSEPVSPFQEKMSPFFTLDLSPTEEKTFKPSDTSPQMGKKPIKSPPLTTSEPVSFALPSCTSESIGGMLITTRNSSTSNWNEEIGITEITNRFPTQMSLPLKEIERAPEEEAHQELKHAQIVAAGKPELPEEGERPMSSSQNKTVPSGHAQPGAVALDSPQDPVPVSSVSLIPPPPPKNAARMLALALAESAQQASAQSQKKPGDAHSESTSYGETEAATALEKLHLSAGAPDKLHLYTDLPENQLHFQTSAPVEQDFQASSTAREQNHPPGAPGSQDPQPLHTSVPGDVPARRDAEQEQSSYLAGQTENKEQFPAHAEDWEQTRQHAPGALPDWEPPTTNLPMDKPHVRACTSGDKQLTSTCAADDKLETPVTAGEKSTPVPVPYLTTIQTAAAEPTRAPTCQHAAGPAIIQADVTGTSAQRTPTGSQPAPPQRQDHQSAVGQVPAASAKASSNSSQVWGAAAPEKPPEPAPGFATESTSSTHRSSSVPSGHQSRLEKPREGTRAPMLHLRSESVPTHSSYSFTPPVPPVRTLESKIAAAMHSNNADAINNSNYHAFLASSMLASSVEEVLLPPPAPPPPPLPPPPLAPPPPPPPPPKHSSLQSVYVPHPKPESILEPSGPDVYLHHKPTSIHQYRPESVPPHMTYHSKPDQHPAYPPRSETPTSAGSRYNTYTNQGRSTSAVYSKPRSRLEFVSSVSPTGLRNAAYGEDPPPYPTIRRVQSLHVPTPAASTIRSVPISRTEVPPDDEPLFCPRPLYQYKPYQPHSDYHVTQLQPYFENGRVHYRYSPYSSSSGSSYYTSADGNFYDLDPYSTMRVRPFHPLHSRDFASYEARLHSKGLYRYPGLSAYPRGGLIGHLAGKEHSFISRDVPPAPDIKHMYMSWDLEDMEKYRMQSIRRESRTRQKMKGPLMSQYDNVTPLLPEDPGGPDIIHLRSKSDPGKSGLLTVAEGKEGKYPAKAATPDGDERYYMQHPEPELDRAHYHGAYGNGQPEKPSLPQKQSSIRSRKMHEPTCSASDHRPHLQQEPSHRQPSEPKNGPPYPDYRPKGPEPAEPMGYQHLGRKYFLANQDTLRLNHKEARLAEDRPDLERSRARPSTSVEKHSRDGYKEEEHAASPMAPPPSPERSHSLRVQHRESVEKDSALFYPYQTLGKRQSTMTVMSQYDNVEDYHTMPQHQRGGYAGEGGCVPPTFTHVHSRIYATALGQGAFLPTELCLQRPETEVHVE", "length": 2038, "header": "tr|A0A8V1A0R7-1|A0A8V0ZMZ0_CHICK Computationally mapped isoform of Rho GTPase-activating protein 32 OS=Gallus gallus OX=9031 GN=ARHGAP33 PE=3 SV=1 CANONICAL=A0A8V0ZMZ0-1" }, "locus": { "chromosome": "24", "start_pos": 1309658, "end_pos": 1204892, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057159.1", "url": "https://www.ensembl.org/id/ENSGALT00010057159.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034767.1", "url": "https://www.ensembl.org/id/ENSGALP00010034767.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase cycle" }, { "id": "R-GGA-9013106", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013106", "resource": "Reactome", "description": "RHOC GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-GGA-9013408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013408", "resource": "Reactome", "description": "RHOG GTPase cycle" }, { "id": "R-GGA-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" }, { "id": "R-GGA-9035034", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9035034", "resource": "Reactome", "description": "RHOF GTPase cycle" }, { "id": "R-GGA-9768727", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9768727", "resource": "Reactome", "description": "Regulation of CDH1 posttranslational processing and trafficking to plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LN08-1", "protein_name": "Rho GTPase-activating protein 32", "gene_name": "Arhgap32", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"length": 2112 }, "evidence": [ { "id": "A0A8V0ZMZ0", "url": "https://omabrowser.org/oma/group/A0A8V0ZMZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A7KAX9-1", "protein_name": "Rho GTPase-activating protein 32", "gene_name": "ARHGAP32", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" }, { "name": "regulation of dendritic spine morphogenesis", "id": "GO:0061001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061001", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" }, { "name": "regulation of postsynapse assembly", "id": "GO:0150052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150052", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZMZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1294, "end_pos": 1296, "annotation": 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"glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZMZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMZ0" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 307, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1294, "end_pos": 1296 }, { "start_pos": 1390, "end_pos": 1392 }, { "start_pos": 1755, "end_pos": 1757 }, { "start_pos": 547, "end_pos": 549 }, { "start_pos": 913, "end_pos": 915 }, 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"MRCRKRALLVLALCLPLGLWLLFRASVSGLGLPPSLPTVRCTASANASAWFSARYDAAAGPLLTGPAHELSPDVVHWWLTLQGTPSIVPLRAILQKLFAVVPAPNGSVWDPSHCRTCAVVGNSGRLKGSRHGLQIDAHHWVLRMNRAKTAGFEMDVGARTTHHFMYPESAMNLWPGVHLVLVPFKPLDLKWVTSAFSTGELTHTYTRVKQFIKADRNKVLILSPAFLKYIHENWTERHGRSPCLASVPTAKGTGITTGKKTAGLERSAGQGSTMLMSSSASSKDWQLKAEYYSINDTHSRNEAKPLAQEAAAAAAL", "length": 316, "header": "tr|A0A8V0ZN18-1|A0A8V0ZN18_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=ST3GAL8 PE=3 SV=1 CANONICAL=A0A8V0ZN18-1" }, "locus": { "chromosome": "20", "start_pos": 1495741, "end_pos": 1493344, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053253.1", "url": "https://www.ensembl.org/id/ENSGALT00010053253.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032096.1", "url": "https://www.ensembl.org/id/ENSGALP00010032096.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { 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"https://www.uniprot.org/uniprotkb/A0A8V0ZN24/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning. Modulates the histone chaperone function and the RNA-binding activity of nucleolar phosphoprotein B23/NPM. Efficiently mediates chromatin remodeling when included in a pentamer containing NPM3 and NPM.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN29#function" }, { "database": "UniProtKB", "id": "ARBA00055184", "url": "https://www.uniprot.org/uniprotkb/ARBA00055184#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN24" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN24", "locus": { "chromosome": "6", "start_pos": 23496501, "end_pos": 23493201, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021034", "url": 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"Protein" ] } ], "sequence": { "sequence": "MEPHGPGSVLFGCELTASTKSYTFQVDEDDDSDHVLALSAHSPSLAQLHQGAPWAELSALAAQMGLLLSVIFRSCCSKVVSGGSLWNTPAVGQRKIFFLVFDLAGTPHQLGPWPVALQAQVCLTDGAKDECNVVEVIGRNHKNQEITVPVANLKLSCQPLLSLDNFKLQPPVTFRLAAGSGPVHLAGWHQILHRDDASFEEEEEDDDDDMSEEEIAPIVPAKKERRKQ", "length": 228, "header": "tr|A0A8V0ZN24-1|A0A8V0ZN24_CHICK Isoform 1 of Nucleophosmin/nucleoplasmin 3 OS=Gallus gallus OX=9031 GN=NPM3 PE=1 SV=1 CANONICAL=A0A8V0ZN24-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZN24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN24/entry#A0A8V0ZN24-1", "sequence": { "sequence": "MEPHGPGSVLFGCELTASTKSYTFQVDEDDDSDHVLALSAHSPSLAQLHQGAPWAELSALAAQMGLLLSVIFRSCCSKVVSGGSLWNTPAVGQRKIFFLVFDLAGTPHQLGPWPVALQAQVCLTDGAKDECNVVEVIGRNHKNQEITVPVANLKLSCQPLLSLDNFKLQPPVTFRLAAGSGPVHLAGWHQILHRDDASFEEEEEDDDDDMSEEEIAPIVPAKKERRKQ", "length": 228, "header": "tr|A0A8V0ZN24-1|A0A8V0ZN24_CHICK Isoform 1 of Nucleophosmin/nucleoplasmin 3 OS=Gallus gallus OX=9031 GN=NPM3 PE=1 SV=1 CANONICAL=A0A8V0ZN24-1" }, "locus": { "chromosome": "6", "start_pos": 23495849, "end_pos": 23493322, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050889.1", "url": "https://www.ensembl.org/id/ENSGALT00010050889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030080.1", "url": "https://www.ensembl.org/id/ENSGALP00010030080.1" } ] } }, { "isoform_ac": "A0A8V0ZN29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN24/entry#A0A8V0ZN29-1", "sequence": { "sequence": "MEPHGPGSVLFGCELTASTKSYTFQVDEDDDSDHVLALSVVCLTDGAKDECNVVEVIGRNHKNQEITVPVANLKLSCQPLLSLDNFKLQPPVTFRLAAGSGPVHLAGWHQILHRDDASFEEEEEDDDDDMSEEEIAPIVLAGTSPQTAVTSDASQQDLNFCCLFFFF", "length": 167, "header": "tr|A0A8V0ZN29-1|A0A8V0ZN29_CHICK Computationally mapped isoform of Nucleoplasmin-3 OS=Gallus gallus OX=9031 GN=NPM3 PE=1 SV=1 CANONICAL=A0A8V0ZN24-1" }, "locus": { "chromosome": "6", "start_pos": 23496060, "end_pos": 23493322, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": 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"go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN24" }, { "id": "PF03066", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03066" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleoplasmin core", "eco_id": "ECO_0000259", "start_pos": 120, "end_pos": 191, "start_aa": "Gln", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZN25/entry#A0A8V0ZN25-1", "sequence": { "sequence": "LWRYSRPAWMPTWYIYLAAFLEILSNATIHSIVRLQRETETIQGGVCAVINTSHCHYRDKSCRIEENTEKIKQPLKLCHQISLDDTS", "length": 87, "header": "tr|A0A8V0ZN25-1|A0A8V0ZN25_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZN25-1" }, "locus": { "chromosome": "1", "start_pos": 73369518, "end_pos": 73368502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054404.1", "url": "https://www.ensembl.org/id/ENSGALT00010054404.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032863.1", "url": "https://www.ensembl.org/id/ENSGALP00010032863.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZN31-1", "uniprot_ac": "A0A8V0ZN31", "uniprot_id": "A0A8V0ZN31_CHICK", "mass": { "chemical_mass": 162043.0, "monoisotopic_mass": 162043.0 }, "refseq": {}, "gene_names": [ { "name": "DISP2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZN31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN31" } ] } ], "protein_names": [ { "name": "Dispatched RND transporter family member 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZN31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN31/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN31" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DISP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN31", "locus": { "chromosome": "5", "start_pos": 972380, "end_pos": 937995, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023498", "url": "https://www.ensembl.org/id/ENSGALG00010023498" } ] } } ], "crossref": [ { "id": "428836", "url": "https://www.ncbi.nlm.nih.gov/gene/428836", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428836", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428836", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZN31", "url": "https://www.orthodb.org/?gene=A0A8V0ZN31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWP7", "url": "https://www.orthodb.org/?gene=A0A8V0ZWP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWQ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZWQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45951", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45951", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45951:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45951:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-GGA-5362798", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5362798", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZN31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWP7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEIANTEPSYSGTSWERICPVHHCPIPASPRLGGDHLPSSSHTLGPISTQSNGQVPSSSQDSQQHHLYYSCNQQEPRGSYGLPLLPGHGERSTLCSHLSSSDPVPASHHEALETPWKRWSPGQRLSRPMQHHIVTVRHDKAFRMPKSYSQMIAEWPIAVLVLCSVTVVICTLAGLLVGNLPDFSEPLMGFEPRDTDIGRKLIVWRNVESHTGYKKTFSLSPYAEKKSYDDIGISRGQKAVQGGQEARTRRMVEQIYGVDGFFCGPPEKGYSQLVFMSTTAGSLWNLQAIQSMCQIEQDKIRSHVHFRDLCQRTEANECCPSWSLGNYIAVLYNRSSCLEITQGDISHTLALLRACAPDYHKGILTPSCIGPETMRQKHSQCAKVPEKCTRFNAIYQLLHFLVDRDFLSPQTIEYQVPSLKYSLLFLPTRKGASMMGIYLDNLESWDLFDNYTSITGMDLGLKQKLFQHYLLLDTKYPVLAIFAIFLSVSFYLRSVFITLMVLLTVVSSLMISYFLYKVAFRFTYFPFVNLTAVIILSSICANHTFVFFDLWNLSKSQNPSAGLSQRVSQTMHHFAYLMLASCFTTGAAFYASYISNIIAIRCFAVYMGTSVLVNLVFMMTWLPSSAVLYERYIATACVYKPEDYWKNTGHKRVALSLHYVLRGLQKTLCETSKLLFEKLLPCGVIKFRYIWICWFAALAIGGAYISCSNPKLKLPTLESSSVQVFRLSHPFERYDSEYCHQFMFERLERGEGQRMPVTIIWGILPVDNGDHFNPKSNGTLVADATFTIQSPDAQKWLFEFCQKVKNQTFYYLDTEQKSTVCFMEEFVRWMDSRQCSQRDNSFSLCCNQFSFPYGSEVFLHCIKMMLLEQGREGAETYDLGLRFDGEGNLAALVLQFQTVYHYSFNYSKAKHFYEEINLWVTEEMKTAPVGLQNGWFTSKLELYNLQHSLSTETMVVMGLSIAISFVVLLLTTWNVLLSVFSVTAIAGTVLVTVGLLVLLEWQLNAVESLFISAAVGLSVDFTVNYCISYHLCPHSDRLSRVAFSLKQMSCATAMAASALFSAGVIMLPATVLAYRKLGIFIMMIKCISCGFASFFFQSLCCFFGPEKNCGQILWPCAHTIKDYSDDSEPNGTYACGGNEKQNRLRKVQESNTANEQYELQPLSRKLSDSFDNSTSTSKLSNRPSVLSEDMQAEDNRCPRIGTHPPLERERQNLQENLGDDQAVLCQCPALQTSSPYKHSSSGAEIHRERLCRDCQCRKYSPKAWDSSGLDYIQPAGVNEEGQLNKSQCSTDTAQQQSDYTSDNSHLPAADIYKIHRCLCSLGSSFDMLNISSETSISDFEQGLKLAESASSCPDVLELSDSYSQTERGYLNGKRDTLRLDLRETVFDISPAASQQNSSSWKNRFGLGSEGPVVLPNSQPDMPDVWIKRSSAQSSGYNS", 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"length": 1403, "header": "tr|A0A8V0ZWP7-1|A0A8V0ZN31_CHICK Computationally mapped isoform of Dispatched RND transporter family member 2 OS=Gallus gallus OX=9031 GN=DISP2 PE=3 SV=1 CANONICAL=A0A8V0ZN31-1" }, "locus": { "chromosome": "5", "start_pos": 971923, "end_pos": 961573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057231.1", "url": "https://www.ensembl.org/id/ENSGALT00010057231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034805.1", "url": "https://www.ensembl.org/id/ENSGALP00010034805.1" } ] } }, { "isoform_ac": "A0A8V0ZWQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN31/entry#A0A8V0ZWQ2-1", "sequence": { "sequence": "MGFCRGLRENEMHFPIAIYHSEKKEMQDLARPVSPCQRLPTLSPATVALLGKESARSITAPFLHRPGWGETTCPPPATRWGQSPPSPMVSDPVPASHHEALETPWKRWSPGQRLSRPMQHHIVTVRHDKAFRMPKSYSQMIAEWPIAVLVLCSVTVVICTLAGLLVGNLPDFSEPLMGFEPRDTDIGRKLIVWRNVESHTGYKKTFSLSPYAEKKSYDDIGISRGQKAVQGGQEARTRRMVEQIYGVDGFFCGPPEKGYSQLVFMSTTAGSLWNLQAIQSMCQIEQDKIRSHVHFRDLCQRTEANECCPSWSLGNYIAVLYNRSSCLEITQGDISHTLALLRACAPDYHKGILTPSCIGPETMRQKHSQCAKVPEKCTRFNAIYQLLHFLVDRDFLSPQTIEYQVPSLKYSLLFLPTRKGASMMGIYLDNLESWDLFDNYTSITGMDLGLKQKLFQHYLLLDTKYPVLAIFAIFLSVSFYLRSVFITLMVLLTVVSSLMISYFLYKVAFRFTYFPFVNLTAVIILSSICANHTFVFFDLWNLSKSQNPSAGLSQRVSQTMHHFAYLMLASCFTTGAAFYASYISNIIAIRCFAVYMGTSVLVNLVFMMTWLPSSAVLYERYIATACVYKPEDYWKNTGHKRVALSLHYVLRGLQKTLCETSKLLFEKLLPCGVIKFRYIWICWFAALAIGGAYISCSNPKLKLPTLESSSVQVFRLSHPFERYDSEYCHQFMFERLERGEGQRMPVTIIWGILPVDNGDHFNPKSNGTLVADATFTIQSPDAQKWLFEFCQKVKNQTFYYLDTEQKSTVCFMEEFVRWMDSRQCSQRDNSFSLCCNQFSFPYGSEVFLHCIKMMLLEQGREGAETYDLGLRFDGEGNLAALVLQFQTVYHYSFNYSKAKHFYEEINLWVTEEMKTAPVGLQNGWFTSKLELYNLQHSLSTETMVVMGLSIAISFVVLLLTTWNVLLSVFSVTAIAGTVLVTVGLLVLLEWQLNAVESLFISAAVGLSVDFTVNYCISYHLCPHSDRLSRVAFSLKQMSCATAMAASALFSAGVIMLPATVLAYRKLGIFIMMIKCISCGFASFFFQSLCCFFGPEKNCGQILWPCAHTIKDYSDDSEPNGTYACGGNEKQNRLRKVQESNTANEQYELQPLSRKLSDSFDNSTSTSKLSNRPSVLSEDMQAEDNRCPRIGTHPPLERERQNLQENLGDDQAVLCQCPALQTSSPYKHSSSGAEIHRERLCRDCQCRKYSPKAWDSSGLDYIQPAGVNEEGQLNKSQCSTDTAQQQSDYTSDNSHLPAADIYKIHRCLCSLGSSFDMLNISSETSISDFEQGLKLAESASSCPDVLELSDSYSQTERGYLNGKRDTLRLDLRETVFDISPAASQQNSSSWKNRFGLGSEGPVVLPNSQPDMPDVWIKRSSAQSSGYNS", "length": 1427, "header": "tr|A0A8V0ZWQ2-1|A0A8V0ZN31_CHICK Computationally mapped isoform of Dispatched RND transporter family member 2 OS=Gallus gallus OX=9031 GN=DISP2 PE=3 SV=1 CANONICAL=A0A8V0ZN31-1" }, "locus": { "chromosome": "5", "start_pos": 971923, "end_pos": 938168, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057243.1", "url": "https://www.ensembl.org/id/ENSGALT00010057243.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034810.1", "url": "https://www.ensembl.org/id/ENSGALP00010034810.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428836", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428836", "resource": "KEGG Pathway" }, { "id": "R-GGA-5362798", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5362798", "resource": "Reactome", "description": "Release of Hh-Np from the secreting cell" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1131, "end_pos": 1133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1173, "end_pos": 1175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1285, "end_pos": 1287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1330, "end_pos": 1332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1397, "end_pos": 1399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 530, "end_pos": 532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 906, "end_pos": 908, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZN31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN31" }, { "id": "PS50156", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SSD", "eco_id": "ECO_0000259", "start_pos": 480, "end_pos": 629, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1131, "end_pos": 1133 }, { "start_pos": 1173, "end_pos": 1175 }, { "start_pos": 1285, "end_pos": 1287 }, { "start_pos": 1330, "end_pos": 1332 }, { "start_pos": 1397, "end_pos": 1399 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 530, "end_pos": 532 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 778, "end_pos": 780 }, { "start_pos": 807, "end_pos": 809 }, { "start_pos": 906, "end_pos": 908 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPT2-1", "uniprot_ac": "A0A8V0ZPT2", "uniprot_id": "A0A8V0ZPT2_CHICK", "mass": { "chemical_mass": 39188.0, "monoisotopic_mass": 39188.0 }, "refseq": {}, "gene_names": [ { "name": "PLEKHF1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain-containing family F member 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. 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"PLEKHF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2", "locus": { "chromosome": "11", "start_pos": 8027672, "end_pos": 8015784, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023954", "url": "https://www.ensembl.org/id/ENSGALG00010023954" } ] } } ], "crossref": [ { "id": "A0A8V0ZPT2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPT2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000004474", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000004474", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01218", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01218", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15754", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15754", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427546", "url": "https://www.ncbi.nlm.nih.gov/gene/427546", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427546", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427546", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DDKADQW", "url": "https://omabrowser.org/oma/group/DDKADQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPT2", "url": "https://www.orthodb.org/?gene=A0A8V0ZPT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYN9", "url": "https://www.orthodb.org/?gene=A0A8V0ZYN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BSW6", "url": "https://www.orthodb.org/?gene=E1BSW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46280", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46280", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46280:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46280:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYN9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSW6", "url": "https://www.uniprot.org/uniprotkb/E1BSW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BSW6-1", "url": "https://www.uniprot.org/uniprotkb/E1BSW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVQSEMGDWLQRPRMSSLCCIQPIVSQLTALARRLCSCAGRDRRAWLRSPPAVTVQKLPVCEVFQGELEMVDHLANTEINSQRIAAVENCFGASGQPLAVPGRVLLGEGILTKECRKKPKPRIFFLFNDILVYGSIVINKRKYNSQHIIPLEDVTLETLPDTLQMKNRWMIKTSKKSFVVSAASLTERKEWISHLEECIRHLLTKTGRQPSTEHAAPWIPDKATDICMRCTQTKFSTLTRRHHCRKCGFVVCGDCSRQRFLMPRLSPKPLRVCNLCYRQLLAEQKKEEEADCQQPEQYRSAIPGYEPSSGDDSDKSDDYKVDQWPADTEFYTSEVSWSSFHS", "length": 343, "header": "tr|A0A8V0ZPT2-1|A0A8V0ZPT2_CHICK Isoform 1 of Pleckstrin homology domain-containing family F member 1 OS=Gallus gallus OX=9031 GN=PLEKHF1 PE=1 SV=1 CANONICAL=A0A8V0ZPT2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2/entry#A0A8V0ZPT2-1", "sequence": { "sequence": "MSVQSEMGDWLQRPRMSSLCCIQPIVSQLTALARRLCSCAGRDRRAWLRSPPAVTVQKLPVCEVFQGELEMVDHLANTEINSQRIAAVENCFGASGQPLAVPGRVLLGEGILTKECRKKPKPRIFFLFNDILVYGSIVINKRKYNSQHIIPLEDVTLETLPDTLQMKNRWMIKTSKKSFVVSAASLTERKEWISHLEECIRHLLTKTGRQPSTEHAAPWIPDKATDICMRCTQTKFSTLTRRHHCRKCGFVVCGDCSRQRFLMPRLSPKPLRVCNLCYRQLLAEQKKEEEADCQQPEQYRSAIPGYEPSSGDDSDKSDDYKVDQWPADTEFYTSEVSWSSFHS", "length": 343, "header": "tr|A0A8V0ZPT2-1|A0A8V0ZPT2_CHICK Isoform 1 of Pleckstrin homology domain-containing family F member 1 OS=Gallus gallus OX=9031 GN=PLEKHF1 PE=1 SV=1 CANONICAL=A0A8V0ZPT2-1" }, "locus": { "chromosome": "11", "start_pos": 8020694, "end_pos": 8019333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058328.1", "url": "https://www.ensembl.org/id/ENSGALT00010058328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035437.1", "url": "https://www.ensembl.org/id/ENSGALP00010035437.1" } ] } }, { "isoform_ac": "A0A8V0ZYN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2/entry#A0A8V0ZYN9-1", "sequence": { "sequence": "MVDHLANTEINSQRIAAVENCFGASGQPLAVPGRVLLGEGILTKECRKKPKPRIFFLFNDILVYGSIVINKRKYNSQHIIPLEDVTLETLPDTLQMKNRWMIKTSKKSFVVSAASLTERKEWISHLEECIRHLLTKTGRQPSTEHAAPWIPDKATDICMRCTQTKFSTLTRRHHCRKCGFVVCGDCSRQRFLMPRLSPKPLRVCNLCYRQLLAEQKKEEEADCQQPEQYRSAIPGYEPSSGDDSDKSDDYKVDQWPADTEFYTSEVSWSGTTPSHSENVSYTQAESDRLEKSTD", "length": 294, "header": "tr|A0A8V0ZYN9-1|A0A8V0ZPT2_CHICK Computationally mapped isoform of Pleckstrin homology domain-containing family F member 1 OS=Gallus gallus OX=9031 GN=PLEKHF1 PE=1 SV=1 CANONICAL=A0A8V0ZPT2-1" }, "locus": { "chromosome": "11", "start_pos": 8020920, "end_pos": 8019876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058331.1", "url": "https://www.ensembl.org/id/ENSGALT00010058331.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035440.1", "url": "https://www.ensembl.org/id/ENSGALP00010035440.1" } ] } }, { "isoform_ac": "E1BSW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2/entry#E1BSW6-1", "sequence": { "sequence": "MVDHLANTEINSQRIAAVENCFGASGQPLAVPGRVLLGEGILTKECRKKPKPRIFFLFNDILVYGSIVINKRKYNSQHIIPLEDVTLETLPDTLQMKNRWMIKTSKKSFVVSAASLTERKEWISHLEECIRHLLTKTGRQPSTEHAAPWIPDKATDICMRCTQTKFSTLTRRHHCRKCGFVVCGDCSRQRFLMPRLSPKPLRVCNLCYRQLLAEQKKEEEADCQQPEQYRSAIPGYEPSSGDDSDKSDDYKVDQWPADTEFYTSEVSWSSFHS", "length": 273, "header": "tr|E1BSW6-1|A0A8V0ZPT2_CHICK Computationally mapped isoform of Pleckstrin homology domain-containing family F member 1 OS=Gallus gallus OX=9031 GN=PLEKHF1 PE=1 SV=4 CANONICAL=A0A8V0ZPT2-1" }, "locus": { "chromosome": "11", "start_pos": 8020694, "end_pos": 8019876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058336.1", "url": "https://www.ensembl.org/id/ENSGALT00010058336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035445.1", "url": "https://www.ensembl.org/id/ENSGALP00010035445.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427546", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427546", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RNZ0-1", "protein_name": "Pleckstrin homology domain-containing family F member 1", "gene_name": "PLEKHF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVDYLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLEPLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVRRQLLATGLQPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRERFLLPRLSPKPLRVCSLCFRELAAQKQKEEEEEEEEEEQGPRVPGQPAYLAGAVCGASSGDDDDSDEDREGGDGDWPSRVEFYAGGVSWSSFHS", "length": 283 }, "evidence": [ { "id": "A0A8V0ZPT2", "url": "https://omabrowser.org/oma/group/A0A8V0ZPT2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q68FU1-1", "protein_name": "Pleckstrin homology domain-containing family F member 1", "gene_name": "Plekhf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDHLANTEINSQRIAAVENCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLSKRKYRSQHIIPLEEVTLEPLPETLQAKNRWMIKTAKKSFVVSAASTTERQEWISHIEECVRRQLLATGRQPTTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRERFLLPRLSPKPLRVCSLCYRELAAQKRREEAKERFRGSPGQLTHLGSTMCGASSGDDDDSDEDREGSGDGDWPTQVEFYASGVSWSAFHS", "length": 279 }, "evidence": [ { "id": "A0A8V0ZPT2", "url": "https://omabrowser.org/oma/group/A0A8V0ZPT2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" }, { "name": "phosphatidylinositol-5-phosphate binding", "id": "GO:0010314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010314", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" }, { "name": "phosphatidylinositol-4-phosphate binding", "id": "GO:0070273", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070273", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" }, { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" }, { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" }, { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" }, { "name": "positive regulation of autophagy", "id": "GO:0010508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 222, "end_pos": 282, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZPT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT2" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 201, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRB5-1", "uniprot_ac": "A0A8V0ZRB5", "uniprot_id": "A0A8V0ZRB5_CHICK", "mass": { "chemical_mass": 42666.0, "monoisotopic_mass": 42666.0 }, "refseq": {}, "gene_names": [ { "name": "PSMA4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5" } ] } ], "protein_names": [ { "name": "Hydroxylysine kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.81", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-lysine.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5#function" }, { "database": "UniProtKB", "id": "ARBA00037368", "url": "https://www.uniprot.org/uniprotkb/ARBA00037368#function" } ] }, { "annotation": "Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).", "evidence": [ { "database": "UniProtKB", "id": "F1NC02", "url": "https://www.uniprot.org/uniprotkb/F1NC02#function" }, { "database": "UniProtKB", "id": "ARBA00003876", "url": "https://www.uniprot.org/uniprotkb/ARBA00003876#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSMA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5", "locus": { "chromosome": "10", "start_pos": 3668874, "end_pos": 3806137, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024195", "url": "https://www.ensembl.org/id/ENSGALG00010024195" } ] } } ], "crossref": [ { "id": "A0A8V0ZRB5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRB5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003046", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003046", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03752", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03752", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415357", "url": "https://www.ncbi.nlm.nih.gov/gene/415357", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000426", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000426", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415357", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415357", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YVLNDNM", "url": "https://omabrowser.org/oma/group/YVLNDNM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRB5", "url": "https://www.orthodb.org/?gene=A0A8V0ZRB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NC02", "url": "https://www.orthodb.org/?gene=F1NC02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11599", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11599", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21064:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21064:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01636", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01636", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10584", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10584", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-71064", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71064", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "19049", "url": "https://www.rhea-db.org/rhea/19049", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZRB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NC02", "url": "https://www.uniprot.org/uniprotkb/F1NC02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NC02-1", "url": "https://www.uniprot.org/uniprotkb/F1NC02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGDRRQPQAATKPAFGEEEAAELVDKVFGLKAVWVRPLPSYDDQNFHVKVSDGGEAEGAEEYVLKITNSEDSQQPALIEAQTRAMVFLSAHGFPSATPRLTKDGGIMSVQEGGSRPGNQKYVVRLLTYLPGTPVAKIAAPTQLLYDIGKLAASLDKALTEQFHHPSVSSLHRGQFIWNLANVPLLEQYVDALGQNEYREVVEWVIQQFKEKVTPKISSFRPCINHGDLNDHNILVVPGSPRGAAPQYRVSGVLDFSDMSYGRYVFEAAIAIMYMMVESAEPLRVGGHVLAGFESVVPLTGGERAALFLLARCPAAPAPCLEDMTPEPPYFLQKAACTRLSMPWRQSDTRVLAWASWPTMVFCWLQRGATFISSSMRFSSQKRSTN", "length": 387, "header": "tr|A0A8V0ZRB5-1|A0A8V0ZRB5_CHICK Isoform 1 of Hydroxylysine kinase OS=Gallus gallus OX=9031 GN=PSMA4 PE=1 SV=1 CANONICAL=A0A8V0ZRB5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5/entry#A0A8V0ZRB5-1", "sequence": { "sequence": "MASGDRRQPQAATKPAFGEEEAAELVDKVFGLKAVWVRPLPSYDDQNFHVKVSDGGEAEGAEEYVLKITNSEDSQQPALIEAQTRAMVFLSAHGFPSATPRLTKDGGIMSVQEGGSRPGNQKYVVRLLTYLPGTPVAKIAAPTQLLYDIGKLAASLDKALTEQFHHPSVSSLHRGQFIWNLANVPLLEQYVDALGQNEYREVVEWVIQQFKEKVTPKISSFRPCINHGDLNDHNILVVPGSPRGAAPQYRVSGVLDFSDMSYGRYVFEAAIAIMYMMVESAEPLRVGGHVLAGFESVVPLTGGERAALFLLARCPAAPAPCLEDMTPEPPYFLQKAACTRLSMPWRQSDTRVLAWASWPTMVFCWLQRGATFISSSMRFSSQKRSTN", "length": 387, "header": "tr|A0A8V0ZRB5-1|A0A8V0ZRB5_CHICK Isoform 1 of Hydroxylysine kinase OS=Gallus gallus OX=9031 GN=PSMA4 PE=1 SV=1 CANONICAL=A0A8V0ZRB5-1" }, "locus": { "chromosome": "10", "start_pos": 3678692, "end_pos": 3672335, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059035.1", "url": "https://www.ensembl.org/id/ENSGALT00010059035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035999.1", "url": "https://www.ensembl.org/id/ENSGALP00010035999.1" } ] } }, { "isoform_ac": "F1NC02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5/entry#F1NC02-1", "sequence": { "sequence": "MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKTALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKQHEEEEAKAEREKKEKEQKEKDK", "length": 261, "header": "tr|F1NC02-1|A0A8V0ZRB5_CHICK Computationally mapped isoform of Hydroxylysine kinase OS=Gallus gallus OX=9031 GN=PSMA4 PE=1 SV=2 CANONICAL=A0A8V0ZRB5-1" }, "locus": { "chromosome": "10", "start_pos": 3673444, "end_pos": 3668928, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059027.1", "url": "https://www.ensembl.org/id/ENSGALT00010059027.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035991.1", "url": "https://www.ensembl.org/id/ENSGALP00010035991.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:415357", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415357", "resource": "KEGG Pathway" }, { "id": "R-GGA-71064", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-71064", "resource": "Reactome", "description": "Lysine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QL81-1", "protein_name": "Proteasome subunit alpha type", "gene_name": "PSMA4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MICGLCFLLLGRNHLFIFPLQSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK", "length": 281 }, "evidence": [ { "id": "A0A8V0ZRB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3H0C2-1", "protein_name": "Proteasome subunit alpha type", "gene_name": "Psma4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTMIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK", "length": 261 }, "evidence": [ { "id": "A0A8V0ZRB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O81148-1", "protein_name": "Proteasome subunit alpha type-4-A", "gene_name": "PAC1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSRRYDSRTTIFSPEGRLYQVEYAMEAIGNAGSAIGILSKDGVVLIGEKKVTSKLLQTSTSAEKMYKIDDHVACAVAGIMSDANILINTARVQAQRYTFMYQEPMPVEQLVQSLCDTKQGYTQFGGLRPFGVSFLFAGWDKHHGFQLYMSDPSGNYGGWKAAAVGANNQAAQSILKQDYKDDATREEAVELALKVLTKTMDSTSLTSEKLELAEVYLTPSKTVKYHVHSPESLTKLLVKHGVTQPAAETS", "length": 250 }, "evidence": [ { "id": "A0A8V0ZRB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P18053-1", "protein_name": "Proteasome subunit alpha type-4", "gene_name": "Prosalpha3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARRYDSRTTIFSPEGRLYQVEYAMEAISHAGTCLGILAEDGILLAAECRSTNKLLDSAIPSEKIYRLNDNMVCSVAGITSDANVLTSELRLIAQRYQFSYGEVIPCEQLVSHLCDIKQAYTQYGGKRPFGVSLLYMGWDNKYGYQLYQSDPSGNYGGWKATCIGNNFGAAISMLKQELADKENVKLTLADAKDLAIKVLSMTLDTTKLTPEKVEMATLQRVDNKTVYSVLEKPDVEKLIEKYTKVQAEAEAAKKEKQAKQPTK", "length": 264 }, "evidence": [ { "id": "A0A8V0ZRB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P21670-1", "protein_name": "Proteasome subunit alpha type-4", "gene_name": "Psma4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAVKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQREKDK", "length": 261 }, "evidence": [ { "id": "A0A8V0ZRB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23638-1", "protein_name": "Proteasome subunit alpha type-3", "gene_name": "PRE9", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGSRRYDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTTDSSALTYDRLEFATIRKGANDGEVYQKIFKPQEIKDILVKTGITKKDEDEEADEDMK", "length": 258 }, "evidence": [ { "id": "A0A8V0ZRB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB5/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25789-1", "protein_name": "Proteasome subunit alpha type-4", "gene_name": "PSMA4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK", "length": 261 }, "evidence": [ { "id": "A0A8V0ZRB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P34119-1", "protein_name": "Proteasome subunit alpha type-4", "gene_name": "psmA4", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARRYDQRTTIFSPEGRVYQVEYAMTAIRHAGATVGILAKDGIVLAAEKKTTAKLLDSSTSISEKMFKIDEHVVCAVAGITSDANILINYARLSSQRFFYQYQEPMPVEQLVSQICDTKQGYTQYGGLRPFGVSFLYAGWDRHYGFQLYQSDPSGNFAGWKATSIGGENSQVAQSVLRSNYKPDISLKEALQLALKVLTKTMDRSNINSEKLEFSYFTKQGDNVVYHIFTAAELDAFIKETDLEQETEDN", "length": 250 }, "evidence": [ { "id": "A0A8V0ZRB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q3ZCK9-1", "protein_name": "Proteasome subunit alpha type-4", "gene_name": "PSMA4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK", "length": 261 }, "evidence": [ { "id": "A0A8V0ZRB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9R1P0-1", "protein_name": "Proteasome subunit alpha type-4", "gene_name": "Psma4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAVKVLNKTMDVSKLSAEKVEIATLTRESGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKKEKEQREKDK", "length": 261 }, "evidence": [ { "id": "A0A8V0ZRB5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5" } ], "pmid": "" }, { "name": "proteasome core complex, alpha-subunit complex", "id": "GO:0019773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019773", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "hydroxylysine kinase activity", "id": "GO:0047992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047992", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5" } ], "pmid": "" }, { "name": "amino acid kinase activity", "id": "GO:0019202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19049", "name": "", "equation": "(5R)-5-hydroxy-L-lysine + GTP = (5R)-5-phosphooxy-L-lysine + GDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZRB5-1" ], "evidence": [ { "id": "19049", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19049" } ] }, { "id": "R-GGA-6788611", "name": "HYKK phosphorylates 5HLYS", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "mitochondrial matrix", "input_participant_list": [ "R-ALL-6788606" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZRB5-1" ], "evidence": [ { "id": "R-GGA-6788611", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6788611" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-6788606", "participant_name": "5HLYS [mitochondrial matrix]", "crossref": [ { "id": "58357", "database": "ChEBI", "url": "" }, { "id": "ZINC000001719890", "database": "ZINC", "url": "" }, { "id": "HMDB0062570", "database": "HMDB Metabolite", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZRB5", "gene_name": "PSMA4", "activity": [ { "ec_number": "2.7.1.81", "activity": "(5R)-5-hydroxy-L-lysine + GTP = (5R)-5-phosphooxy-L-lysine + GDP + H(+).", "evidence": [ { "id": "A0A8V0ZRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5" } ] }, { "ec_number": "2.7.1.81", "activity": "", "evidence": [ { "id": "A0A8V0ZRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB5" }, { "id": "PF01636", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01636" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminoglycoside phosphotransferase", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 285, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.81", "ec_name": "(5R)-5-hydroxy-L-lysine + GTP = (5R)-5-phosphooxy-L-lysine + GDP + H(+).", "evidence": [ { "id": "2.7.1.81", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.81" }, { "id": "2.7.1.81", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.81" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZR21-1", "uniprot_ac": "A0A8V0ZR21", "uniprot_id": "A0A8V0ZR21_CHICK", "mass": { "chemical_mass": 53372.0, "monoisotopic_mass": 53372.0 }, "refseq": {}, "gene_names": [ { "name": "SNX7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ] } ], "protein_names": [ { "name": "Sorting nexin 7", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SNX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21", "locus": { "chromosome": "8", "start_pos": 12113100, "end_pos": 12148285, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024155", "url": "https://www.ensembl.org/id/ENSGALG00010024155" } ] } } ], "crossref": [ { "id": "A0A8V0ZR21", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR21", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005478", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005478", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07284", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07284", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07666", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07666", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424478", "url": "https://www.ncbi.nlm.nih.gov/gene/424478", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424478", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424478", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PBK6", "url": "https://www.orthodb.org/?gene=A0A1D5PBK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR03", "url": "https://www.orthodb.org/?gene=A0A8V0ZR03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR21", "url": "https://www.orthodb.org/?gene=A0A8V0ZR21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZW68", "url": "https://www.orthodb.org/?gene=A0A8V0ZW68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYB0", "url": "https://www.orthodb.org/?gene=A0A8V0ZYB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45949", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45949", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45949:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45949:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PBK6", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PBK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PBK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR03", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAEGRAPGPTLPPAGGRGLEHLAGVPGATPTPLLTASAEVLEFDDEEDDLEVFSKDTSLAEANSFSPSMPISPSSMINQYKFEDEPELKDLFITVDDPESHITAIETFITYRVVTKTSRGEFDSCEYEVRRRYQDFLWLKSKLEEAHPTLIIPPLPEKFVMKGMVERFSDEFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSVRGGVKNRPEMFTEMNDYMETFSHKINVLDKIAHRIYKEEREYFNEMKEYGPIYTLWSASEEDIADSLKGVASCIDKCCKATEKRMAGLSENLLPVIHEYVLYSEILMGVLKRRDQIQSELDSKVDALANKKADKDLFSEEIGKLEDKVECANNALKADWDRWKQNMQYDMRSAFTKVSDNNLRYYEEVATYTECMLHLKFQGLLREFWLPCSESHLQFDKADEHYCYI", "length": 464, "header": "tr|A0A8V0ZR21-1|A0A8V0ZR21_CHICK Isoform 1 of Sorting nexin 7 OS=Gallus gallus OX=9031 GN=SNX7 PE=3 SV=1 CANONICAL=A0A8V0ZR21-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PBK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21/entry#A0A1D5PBK6-1", "sequence": { "sequence": "MEAEGRAPGPTLPPAGGRGLEHLAGVPGATPTPLLTASAEVLEFDDEEDDLEVFSKDTSLAEANSFSPSMPISPSSMINQYKFEDEPELKDLFITVDDPESHITAIETFITYRVVTKTSRGEFDSCEYEVRRRYQDFLWLKSKLEEAHPTLIIPPLPEKFVMKGMVERFSDEFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSVRGGVKNRPEMFTEMNDYMETFSHKINVLDKIAHRIYKEEREYFNEMKEYGPIYTLWSASEEDIADSLKGVASCIDKCCKATEKRMAGLSENLLPVIHEYVLYSEILMGVLKRRDQIQSELDSKVDALANKKADKDLFSEEIGKLEDKVECANNALKADWDRWKQNMQYDMRSAFTKVSDNNLRYYEEIHVDVYVFQSSNLLTGCPLASV", "length": 445, "header": "tr|A0A1D5PBK6-1|A0A8V0ZR21_CHICK Computationally mapped isoform of Sorting nexin 7 OS=Gallus gallus OX=9031 GN=SNX7 PE=3 SV=1 CANONICAL=A0A8V0ZR21-1" }, "locus": { "chromosome": "8", "start_pos": 12148171, "end_pos": 12126948, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058906.1", "url": "https://www.ensembl.org/id/ENSGALT00010058906.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035871.1", "url": "https://www.ensembl.org/id/ENSGALP00010035871.1" } ] } }, { "isoform_ac": "A0A8V0ZR03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21/entry#A0A8V0ZR03-1", "sequence": { "sequence": "MEAEGRAPGPTLPPAGGRGLEHLAGVPGATPTPLLTASAEVLEFDDEEDDLEVFSKDTSLAEANSFSPSMPISPSSMINQYKFEDEPELKDLFITVDDPESHITAIETFITYRVVTKTSRGEFDSCEYEVRRRYQDFLWLKSKLEEAHPTLIIPPLPEKFVMKGMVERFSDEFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSVRGGVKNRPEMFTEMNDYMETFSHKINVLDKIAHRIYKEEREYFNEMKEYGPIYTLWSASEEDIADSLKGVASCIDKCCKATEKRMAGLSENLLPVIHEYVLYSEILMGVLKRRDQIQSELDSKVDALANKKADKDLCLATWESFLASQTVDHHGEEDSEDRP", "length": 398, "header": "tr|A0A8V0ZR03-1|A0A8V0ZR03_CHICK Computationally mapped isoform of Sorting nexin 7 OS=Gallus gallus OX=9031 GN=SNX7 PE=3 SV=1 CANONICAL=A0A8V0ZR21-1" }, "locus": { "chromosome": "8", "start_pos": 12148171, "end_pos": 12121046, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058910.1", "url": "https://www.ensembl.org/id/ENSGALT00010058910.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035875.1", "url": "https://www.ensembl.org/id/ENSGALP00010035875.1" } ] } }, { "isoform_ac": "A0A8V0ZR21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21/entry#A0A8V0ZR21-1", "sequence": { "sequence": "MEAEGRAPGPTLPPAGGRGLEHLAGVPGATPTPLLTASAEVLEFDDEEDDLEVFSKDTSLAEANSFSPSMPISPSSMINQYKFEDEPELKDLFITVDDPESHITAIETFITYRVVTKTSRGEFDSCEYEVRRRYQDFLWLKSKLEEAHPTLIIPPLPEKFVMKGMVERFSDEFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSVRGGVKNRPEMFTEMNDYMETFSHKINVLDKIAHRIYKEEREYFNEMKEYGPIYTLWSASEEDIADSLKGVASCIDKCCKATEKRMAGLSENLLPVIHEYVLYSEILMGVLKRRDQIQSELDSKVDALANKKADKDLFSEEIGKLEDKVECANNALKADWDRWKQNMQYDMRSAFTKVSDNNLRYYEEVATYTECMLHLKFQGLLREFWLPCSESHLQFDKADEHYCYI", "length": 464, "header": "tr|A0A8V0ZR21-1|A0A8V0ZR21_CHICK Isoform 1 of Sorting nexin 7 OS=Gallus gallus OX=9031 GN=SNX7 PE=3 SV=1 CANONICAL=A0A8V0ZR21-1" }, "locus": { "chromosome": "8", "start_pos": 12148171, "end_pos": 12114192, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058931.1", "url": "https://www.ensembl.org/id/ENSGALT00010058931.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035896.1", "url": "https://www.ensembl.org/id/ENSGALP00010035896.1" } ] } }, { "isoform_ac": "A0A8V0ZW68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21/entry#A0A8V0ZW68-1", "sequence": { "sequence": "MEAEGRAPGPTLPPAGGRGLEHLAGVPGATPTPLLTASAEVLEFDDEEDDLEVFSKDTSLAEANSFSPSMPISPSSMINQYKFEDEPELKDLFITVDDPESHITAIETFITYRVVTKTSRGEFDSCEYEVRRRYQDFLWLKSKLEEAHPTLIIPPLPEKFVMKGMVERFSDEFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSVRGGVKNRPEMFTEMNDYMETFSHKINVLDKIAHRIYKEEREYFNEMKEYGPIYTLWSASEEDIADSLKGVASCIDKCCKATEKRMAGLSENLLPVIHEYVLYSEILMGVLKRRDQIQSELDSKVDALANKKADKDLFSEEIGKLEDKVECANNALKADWDRWKQNMQYDMRSAFTKVSDNNLRYYEEFYRSRSAILICVCGFF", "length": 439, "header": "tr|A0A8V0ZW68-1|A0A8V0ZR21_CHICK Computationally mapped isoform of Sorting nexin 7 OS=Gallus gallus OX=9031 GN=SNX7 PE=3 SV=1 CANONICAL=A0A8V0ZR21-1" }, "locus": { "chromosome": "8", "start_pos": 12148171, "end_pos": 12121128, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058918.1", "url": "https://www.ensembl.org/id/ENSGALT00010058918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035883.1", "url": "https://www.ensembl.org/id/ENSGALP00010035883.1" } ] } }, { "isoform_ac": "A0A8V0ZYB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21/entry#A0A8V0ZYB0-1", "sequence": { "sequence": "MPISPSSMINQYKFEDEPELKDLFITVDDPESHITAIETFITYRVVTKTSRGEFDSCEYEVRRRYQDFLWLKSKLEEAHPTLIIPPLPEKFVMKGMVERFSDEFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSVRGGVKNRPEMFTEMNDYMETFSHKINVLDKIAHRIYKEEREYFNEMKEYGPIYTLWSASEEDIADSLKGVASCIDKCCKATEKRMAGLSENLLPVIHEYVLYSEILMGVLKRRDQIQSELDSKVDALANKKADKDLFSEEIGKLEDKVECANNALKADWDRWKQNMQYDMRSAFTKVSDNNLRYYEEIALCRLLEPNHLR", "length": 367, "header": "tr|A0A8V0ZYB0-1|A0A8V0ZR21_CHICK Computationally mapped isoform of Sorting nexin 7 OS=Gallus gallus OX=9031 GN=SNX7 PE=3 SV=1 CANONICAL=A0A8V0ZR21-1" }, "locus": { "chromosome": "8", "start_pos": 12142849, "end_pos": 12118007, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058925.1", "url": "https://www.ensembl.org/id/ENSGALT00010058925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035890.1", "url": "https://www.ensembl.org/id/ENSGALP00010035890.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11, "start_aa": "Thr", "end_pos": 11, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 30, "start_aa": "Thr", "end_pos": 30, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr30", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424478", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424478", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ], "pmid": "" }, { "name": "mitophagy", "id": "GO:0000423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000423", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ], "pmid": "" }, { "name": "piecemeal microautophagy of the nucleus", "id": "GO:0034727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ], "pmid": "" }, { "name": "positive regulation of autophagosome assembly", "id": "GO:2000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR21", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZR21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR21" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 211, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 11, 30 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZR53/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 278", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Transcriptional regulator that plays a role in many biological processes such as embryogenesis, senescence, T-cell development or neurogenesis. Interacts with the TP53 protein to control genes that are important in proliferation and in the DNA-damage response. Mechanistically, the interaction inhibits the DNA binding and transcriptional activity of TP53/p53. Part of the transcriptional network modulating regulatory T-cell development and controls the generation of the regulatory T-cell pool under homeostatic conditions.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PMX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMX5#function" }, { "database": "UniProtKB", "id": "ARBA00057951", "url": "https://www.uniprot.org/uniprotkb/ARBA00057951#function" }, { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PATZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53", "locus": { "chromosome": "15", "start_pos": 9039334, "end_pos": 9021074, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022649", "url": "https://www.ensembl.org/id/ENSGALG00010022649" } ] } } ], "crossref": [ { "id": "A0A8V0ZR53", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR53", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006934", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006934", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18207", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18207", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416963", "url": "https://www.ncbi.nlm.nih.gov/gene/416963", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": 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}, { "id": "PTHR24394:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PMX5", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PMX5-1", "url": 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"MERVSEAAACGPSSGCYTYQVSRHSADMLHSLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQPGDGAAGGGEGGSAEAAAAGGASAAGGGAPGGGRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIDICQEVIKQSNVQILVPPTRPDIMLFRPGAADLGFPLDMTNGATLAPNGNGIAGMPEDEATRAALTAAQSSLPVLQGVDRLPMVAGPLSPPLLASPFQNVAASAPTLGTKRGRGRPRKANLLDSMMFGAPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDIPPPRLGENGIPGQDDPDAPRKRSRTRKQVACDICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCTICNRGFSSASYLKVHVKTHHGVPLPQVSRHQESIPNGGAAFHCVRTYGIKGQKCSHSDPIESSDSYGDLSDTSDLKTPEKQSTNGSFSCDMAVSKNKMETEAEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "length": 689, "header": "tr|A0A8V0ZR53-1|A0A8V0ZR53_CHICK Isoform 1 of BTB/POZ domain zinc finger transcription factor OS=Gallus gallus OX=9031 GN=PATZ1 PE=4 SV=1 CANONICAL=A0A8V0ZR53-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PMX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53/entry#A0A1D5PMX5-1", "sequence": { "sequence": "MERVSEAAACGPSSGCYTYQVSRHSADMLHSLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQPGDGAAGGGEGGSAEAAAAGGASAAGGGAPGGGRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIDICQEVIKQSNVQILVPPTRPDIMLFRPGAADLGFPLDMTNGATLAPNGNGIAGMPEDEATRAALTAAQSSLPVLQGVDRLPMVAGPLSPPLLASPFQNVAASAPTLGTKRGRGRPRKANLLDSMMFGAPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDIPPPRLGENGIPGQDDPDAPRKRSRTRKQVACDICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQQENGSHHGISSETSTAIEKLKLQETCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCTICNRGFSSASYLKVHVKTHHGVPLPQVSRHQESIPNGGAAFHCVRTYGIKEGQKCSHSDPIESSDSYGDLSDTSDLKTPEKQSTNGSFSCDMAVSKNKMETEAEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "length": 714, "header": "tr|A0A1D5PMX5-1|A0A8V0ZR53_CHICK Computationally mapped isoform of BTB/POZ domain zinc finger transcription factor OS=Gallus gallus OX=9031 GN=PATZ1 PE=4 SV=2 CANONICAL=A0A8V0ZR53-1" }, "locus": { "chromosome": "15", "start_pos": 9038239, "end_pos": 9021116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055097.1", "url": "https://www.ensembl.org/id/ENSGALT00010055097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033319.1", "url": "https://www.ensembl.org/id/ENSGALP00010033319.1" } ] } }, { "isoform_ac": "A0A8V0ZR53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53/entry#A0A8V0ZR53-1", "sequence": { "sequence": "MERVSEAAACGPSSGCYTYQVSRHSADMLHSLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQPGDGAAGGGEGGSAEAAAAGGASAAGGGAPGGGRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIDICQEVIKQSNVQILVPPTRPDIMLFRPGAADLGFPLDMTNGATLAPNGNGIAGMPEDEATRAALTAAQSSLPVLQGVDRLPMVAGPLSPPLLASPFQNVAASAPTLGTKRGRGRPRKANLLDSMMFGAPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDIPPPRLGENGIPGQDDPDAPRKRSRTRKQVACDICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCTICNRGFSSASYLKVHVKTHHGVPLPQVSRHQESIPNGGAAFHCVRTYGIKGQKCSHSDPIESSDSYGDLSDTSDLKTPEKQSTNGSFSCDMAVSKNKMETEAEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "length": 689, "header": "tr|A0A8V0ZR53-1|A0A8V0ZR53_CHICK Isoform 1 of BTB/POZ domain zinc finger transcription factor OS=Gallus gallus OX=9031 GN=PATZ1 PE=4 SV=1 CANONICAL=A0A8V0ZR53-1" }, "locus": { "chromosome": "15", "start_pos": 9038239, "end_pos": 9021116, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055093.1", "url": "https://www.ensembl.org/id/ENSGALT00010055093.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033315.1", "url": "https://www.ensembl.org/id/ENSGALP00010033315.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K420-1", "protein_name": "BTB/POZ domain zinc finger transcription factor", "gene_name": "Patz1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAAMAANSNGIAGSMQPEEEAARATGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPILNGGAAFHCARTYGNKGQKCSHQDLIESSDSYGDLSDASDLKTPEKQSANGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPIGPEGK", "length": 686 }, "evidence": [ { "id": "A0A8V0ZR53", "url": "https://omabrowser.org/oma/group/A0A8V0ZR53/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287B916-1", "protein_name": "BTB/POZ domain zinc finger transcription factor", "gene_name": "PATZ1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIASQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPIPNGGAAFHCARTYGNKEGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSTNGSFCDMAVPKNKLESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPTLGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "length": 581 }, "evidence": [ { "id": "A0A8V0ZR53", "url": "https://omabrowser.org/oma/group/A0A8V0ZR53/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5NBY9-1", "protein_name": "POZ (BTB) and AT hook-containing zinc finger 1", "gene_name": "Patz1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAAMAANSNGIAGSMQPEEEAARATGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTSKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPILNGGAAFHCARTYGNKEGQKCSHQDLIESSDSYGDLSDASDLKTPEKQSANGSFSCDVAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "length": 687 }, "evidence": [ { "id": "A0A8V0ZR53", "url": "https://omabrowser.org/oma/group/A0A8V0ZR53/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HBE1-1", "protein_name": "POZ-, AT hook-, and zinc finger-containing protein 1", "gene_name": "PATZ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPILNGGAAFHCARTYGNKEGQKCSHQDPIESSDSYGDLSDASDLKTPEKQSANGSFSCDMAVPKNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "length": 687 }, "evidence": [ { "id": "A0A8V0ZR53", "url": "https://omabrowser.org/oma/group/A0A8V0ZR53/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" }, { "name": "negative regulation of endothelial cell migration", "id": "GO:0010596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010596", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 585, "end_pos": 587, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZR53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 137, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZR53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR53" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 295, "end_pos": 317, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 451, "end_pos": 453 }, { "start_pos": 585, "end_pos": 587 }, { "start_pos": 654, "end_pos": 656 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQT5-1", "uniprot_ac": "A0A8V0ZQT5", "uniprot_id": "A0A8V0ZQT5_CHICK", "mass": { "chemical_mass": 67067.0, "monoisotopic_mass": 67067.0 }, "refseq": { "ac": "XP_003642529", "name": "solute carrier family 13 member 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642529" }, "gene_names": [ { "name": "SLC13A3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "name": "SLC13A3", "type": "synonym", "evidence": [ { "id": "XP_003642529", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642529" } ] } ], "protein_names": [ { "name": "Solute carrier family 13 member 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 13 member 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_003642529", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642529" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_003642529.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003642529", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642529" } ] }, { "annotation": "Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZK22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK22#function" }, { "database": "UniProtKB", "id": "ARBA00056624", "url": "https://www.uniprot.org/uniprotkb/ARBA00056624#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC13A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5", "locus": { "chromosome": "20", "start_pos": 5893903, "end_pos": 5928588, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021478", "url": "https://www.ensembl.org/id/ENSGALG00010021478" } ] } } ], "crossref": [ { "id": "A0A8V0ZQT5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01115", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01115", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770495", "url": "https://www.ncbi.nlm.nih.gov/gene/770495", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:770495", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770495", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZCW1", "url": "https://www.orthodb.org/?gene=A0A8V0ZCW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK08", "url": "https://www.orthodb.org/?gene=A0A8V0ZK08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK12", "url": "https://www.orthodb.org/?gene=A0A8V0ZK12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK17", "url": "https://www.orthodb.org/?gene=A0A8V0ZK17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK22", "url": "https://www.orthodb.org/?gene=A0A8V0ZK22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQT5", "url": "https://www.orthodb.org/?gene=A0A8V0ZQT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10283", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10283", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10283:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10283:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00939", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00939", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06293", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06293", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9955298", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9955298", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003642529", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003642529", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZCW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK08", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK12", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALGALVKKAWSVRRAVVLLGAPLALLPVLLSLPAKEGRCLYVILLMALYWCTEALPLAVTALLPIVLFPFLGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALRVLMCVGVQPARLILGMMLTTSFLSMWLSNTASTAMMLPIANAILKSLFGEKDTSKEMSRENEETQAPLQQNKLYTVPTEMQFLASTEDKDLAEEKEITSDVLSDLKKEEEYKNNIWKGFLISIPYAASIGGTATLTGTAPNLILLGQLKSYFPECDVVNFGSWFMFAFPLMLIFLLMGWLWISILYGGINLRGWRAKKSNLRVDAEARAREVIKEDYQKLGPTKFAEQAIFFFFFMFAVMLFSRDPKFIPGWASFFAPGFISDAVTGITIVIILFFFPSQKPSLKWWFDFKAPNTETQPLLTWRKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGRLHPLEGVPPPVAVILITIVIALFTEFASNTATIIIFLPVLAELAIRLKVNPLYLMIPGTIGCSYAFMLPVSTPPNSIAFSSGHLMVKDMARTGLLMNLMGVLLLSLAMNTWAKSIFQLGTFPAWANIHAENATSLLPAVENVTLSALNKI", "length": 605, "header": "tr|A0A8V0ZQT5-1|A0A8V0ZQT5_CHICK Isoform 1 of Solute carrier family 13 member 3 OS=Gallus gallus OX=9031 GN=SLC13A3 PE=3 SV=1 CANONICAL=A0A8V0ZQT5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5/entry#A0A8V0ZCW1-1", "sequence": { "sequence": "MNAGRDPTLYGQLYSCRGIPAPVVYFVDYASNCIYLEDIVGAIAVQDHIYSVQRSGSDASSLLGLAEKMGQLLARMHDEDLIHGDLTTSNVLLRPPVERLDLVLIDFGLSFISGLPEDKGVDLYVLEKAFLSTHPDTETVFQALLQSYAAASKKSSPVIKRLDEEGRCLYVILLMALYWCTEALPLAVTALLPIVLFPFLGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALRVLMCVGVQPARLILGMMLTTSFLSMWLSNTASTAMMLPIANAILKSLFGEKDTSKEMSRENEETQAPLQQNKLYTVPTEMQFLASTEDKDLAEEKEITSDVLSDLKKEEEYKNNIWKGFLISIPYAASIGGTATLTGTAPNLILLGQLKSYFPECDVVNFGSWFMFAFPLMLIFLLMGWLWISILYGGINLRGWRAKKSNLRVDAEARAREVIKEDYQKLGPTKFAEQAIFFFFFMFAVMLFSRDPKFIPGWASFFAPGFISDAVTGITIVIILFFFPSQKPSLKWWFDFKAPNTETQPLLTWRKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGRLHPLEGVPPPVAVILITIVIALFTEFASNTATIIIFLPVLAELAIRLKVNPLYLMIPGTIGCSYAFMLPVSTPPNSIAFSSGHLMVKDMARTGLLMNLMGVLLLSLAMNTWAKSIFQLGTFPAWANIHAENATSLLPAVENVTLSALNKI", "length": 732, "header": "tr|A0A8V0ZCW1-1|A0A8V0ZQT5_CHICK Computationally mapped isoform of Solute carrier family 13 member 3 OS=Gallus gallus OX=9031 GN=SLC13A3 PE=3 SV=1 CANONICAL=A0A8V0ZQT5-1" }, "locus": { "chromosome": "20", "start_pos": 5928389, "end_pos": 5895268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052098.1", "url": "https://www.ensembl.org/id/ENSGALT00010052098.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031108.1", "url": "https://www.ensembl.org/id/ENSGALP00010031108.1" } ] } }, { "isoform_ac": "A0A8V0ZK08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5/entry#A0A8V0ZK08-1", "sequence": { "sequence": "MAALGALVKKAWSVRRAVVLLGAPLALLPVLLSLPAKEGRCLYVILLMALYWCTEALPLAVTALLPIVLFPFLGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALRVLMCVGVQPARLILGMMLTTSFLSMWLSNTASTAMMLPIANAILKSLFGEKDTSKEMSRENEETQAPLQQNKLYTVPTEMQFLASTEDKDLAEEKEITSDVLSDLKKEEEYKNNIWKGFLISIPYAASIGGTATLTGTAPNLILLGQLKSYFPECDVVNFGSWFMFAFPLMLIFLLMGWLWISILYGGINLRGWRAKKSNLRVDAEARAREVIKEDYQKLGPTKFISDAVTGITIVIILFFFPSQKPSLKWWFDFKAPNTETQPLLTWRKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGRLHPLEGVPPPVAVILITIVIALFTEFASNTATIIIFLPVLAELAIRLKVNPLYLMIPGTIGCSYAFMLPVSTPPNSIAFSSGHLMVKDMARTGLLMNLMGVLLLSLAMNTWAKSIFQLGTFPAWANIHAENATSLLPAVENVTLSALNKI", "length": 570, "header": "tr|A0A8V0ZK08-1|A0A8V0ZQT5_CHICK Computationally mapped isoform of Solute carrier family 13 member 3 OS=Gallus gallus OX=9031 GN=SLC13A3 PE=3 SV=1 CANONICAL=A0A8V0ZQT5-1" }, "locus": { "chromosome": "20", "start_pos": 5917831, "end_pos": 5895268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052074.1", "url": "https://www.ensembl.org/id/ENSGALT00010052074.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031086.1", "url": "https://www.ensembl.org/id/ENSGALP00010031086.1" } ] } }, { "isoform_ac": "A0A8V0ZK12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5/entry#A0A8V0ZK12-1", "sequence": { "sequence": "MAALGALVKKAWSVRRAVVLLGAPLALLPVLLSLPAKEGRCLYVILLMALYWCTEALPLAVTALLPIVLFPFLGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALRVLMCVGVQPARLILGMMLTTSFLSMWLSNTASTAMMLPIANAILKSLFGEKDTSKEMSRENEETQDLAEEKEITSDVLSDLKKEEEYKNNIWKGFLISIPYAASIGGTATLTGTAPNLILLGQLKSYFPECDVVNFGSWFMFAFPLMLIFLLMGWLWISILYGGINLRGWRAKKSNLRVDAEARAREVIKEDYQKLGPTKFAEQAIFFFFFMFAVMLFSRDPKFIPGWASFFAPGFISDAVTGITIVIILFFFPSQKPSLKWWFDFKAPNTETQPLLTWRKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGRLHPLEGVPPPVAVILITIVIALFTEFASNTATIIIFLPVLAELAIRLKVNPLYLMIPGTIGCSYAFMLPVSTPPNSIAFSSGHLMVKDMARTGLLMNLMGVLLLSLAMNTWAKSIFQLGTFPAWANIHAENATSLLPAVENVTLSALNKI", "length": 581, "header": "tr|A0A8V0ZK12-1|A0A8V0ZQT5_CHICK Computationally mapped isoform of Solute carrier family 13 member 3 OS=Gallus gallus OX=9031 GN=SLC13A3 PE=3 SV=1 CANONICAL=A0A8V0ZQT5-1" }, "locus": { "chromosome": "20", "start_pos": 5917831, "end_pos": 5895268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052079.1", "url": "https://www.ensembl.org/id/ENSGALT00010052079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031091.1", "url": "https://www.ensembl.org/id/ENSGALP00010031091.1" } ] } }, { "isoform_ac": "A0A8V0ZK17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5/entry#A0A8V0ZK17-1", "sequence": { "sequence": "MPWRLCLHRDPLHVGVKMPCQHRSSEGRCLYVILLMALYWCTEALPLAVTALLPIVLFPFLGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALRVLMCVGVQPARLILGMMLTTSFLSMWLSNTASTAMMLPIANAILKSLFGEKDTSKEMSRENEETQAPLQQNKLYTVPTEMQFLASTEDKDLAEEKEITSDVLSDLKKEEEYKNNIWKGFLISIPYAASIGGTATLTGTAPNLILLGQLKSYFPECDVVNFGSWFMFAFPLMLIFLLMGWLWISILYGGINLRGWRAKKSNLRVDAEARAREVIKEDYQKLGPTKFAEQAIFFFFFMFAVMLFSRDPKFIPGWASFFAPGFISDAVTGITIVIILFFFPSQKPSLKWWFDFKAPNTETQPLLTWRKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGRLHPLEGVPPPVAVILITIVIALFTEFASNTATIIIFLPVLAELAIRLKVNPLYLMIPGTIGCSYAFMLPVSTPPNSIAFSSGHLMVKDMARTGLLMNLMGVLLLSLAMNTWAKSIFQLGTFPAWANIHAENATSLLPAVENVTLSALNKI", "length": 593, "header": "tr|A0A8V0ZK17-1|A0A8V0ZQT5_CHICK Computationally mapped isoform of Solute carrier family 13 member 3 OS=Gallus gallus OX=9031 GN=SLC13A3 PE=3 SV=1 CANONICAL=A0A8V0ZQT5-1" }, "locus": { "chromosome": "20", "start_pos": 5921337, "end_pos": 5895268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052084.1", "url": "https://www.ensembl.org/id/ENSGALT00010052084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031096.1", "url": "https://www.ensembl.org/id/ENSGALP00010031096.1" } ] } }, { "isoform_ac": "A0A8V0ZK22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5/entry#A0A8V0ZK22-1", "sequence": { "sequence": "MAAAAGDAGAAGAEDGAAGPVRDGAERGEPGPGAVEAAPPPLPGLQLVQQGAEARVYRGSFLGRAAVAKLRFPKLYRHPALEERLSRRRTAQEARSLLRCRRAGIPAPVVYFVDYASNCIYLEDIVGAIAVQDHIYSVQRSGSDASSLLGLAEKMGQLLARMHDEDLIHGDLTTSNVLLRPPVERLDLVLIDFGLSFISGLPEDKGVDLYVLEKAFLSTHPDTETVFQALLQSYAAASKKSSPVIKRLDEEGRCLYVILLMALYWCTEALPLAVTALLPIVLFPFLGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALRVLMCVGVQPARLILGMMLTTSFLSMWLSNTASTAMMLPIANAILKSLFGEKDTSKEMSRENEETQAPLQQNKLYTVPTEMQFLASTEDKDLAEEKEITSDVLSDLKKEEEYKNNIWKGFLISIPYAASIGGTATLTGTAPNLILLGQLKSYFPECDVVNFGSWFMFAFPLMLIFLLMGWLWISILYGGINLRGWRAKKSNLRVDAEARAREVIKEDYQKLGPTKFAEQAIFFFFFMFAVMLFSRDPKFIPGWASFFAPGFISDAVTGITIVIILFFFPSQKPSLKWWFDFKAPNTETQPLLTWRKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGRLHPLEGVPPPVAVILITIVIALFTEFASNTATIIIFLPVLAELAIRLKVNPLYLMIPGTIGCSYAFMLPVSTPPNSIAFSSGHLMVKDMARTGLLMNLMGVLLLSLAMNTWAKSIFQLGTFPAWANIHAENATSLLPAVENVTLSALNKI", "length": 818, "header": "tr|A0A8V0ZK22-1|A0A8V0ZQT5_CHICK Computationally mapped isoform of Solute carrier family 13 member 3 OS=Gallus gallus OX=9031 GN=SLC13A3 PE=3 SV=1 CANONICAL=A0A8V0ZQT5-1" }, "locus": { "chromosome": "20", "start_pos": 5924163, "end_pos": 5895268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052089.1", "url": "https://www.ensembl.org/id/ENSGALT00010052089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031101.1", "url": "https://www.ensembl.org/id/ENSGALP00010031101.1" } ] } }, { "isoform_ac": "A0A8V0ZQT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5/entry#A0A8V0ZQT5-1", "sequence": { "sequence": "MAALGALVKKAWSVRRAVVLLGAPLALLPVLLSLPAKEGRCLYVILLMALYWCTEALPLAVTALLPIVLFPFLGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALRVLMCVGVQPARLILGMMLTTSFLSMWLSNTASTAMMLPIANAILKSLFGEKDTSKEMSRENEETQAPLQQNKLYTVPTEMQFLASTEDKDLAEEKEITSDVLSDLKKEEEYKNNIWKGFLISIPYAASIGGTATLTGTAPNLILLGQLKSYFPECDVVNFGSWFMFAFPLMLIFLLMGWLWISILYGGINLRGWRAKKSNLRVDAEARAREVIKEDYQKLGPTKFAEQAIFFFFFMFAVMLFSRDPKFIPGWASFFAPGFISDAVTGITIVIILFFFPSQKPSLKWWFDFKAPNTETQPLLTWRKAQETVPWNIILLLGGGFAMAKGCEESGLSVWIGGRLHPLEGVPPPVAVILITIVIALFTEFASNTATIIIFLPVLAELAIRLKVNPLYLMIPGTIGCSYAFMLPVSTPPNSIAFSSGHLMVKDMARTGLLMNLMGVLLLSLAMNTWAKSIFQLGTFPAWANIHAENATSLLPAVENVTLSALNKI", "length": 605, "header": "tr|A0A8V0ZQT5-1|A0A8V0ZQT5_CHICK Isoform 1 of Solute carrier family 13 member 3 OS=Gallus gallus OX=9031 GN=SLC13A3 PE=3 SV=1 CANONICAL=A0A8V0ZQT5-1" }, "locus": { "chromosome": "20", "start_pos": 5917831, "end_pos": 5895268, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052082.1", "url": "https://www.ensembl.org/id/ENSGALT00010052082.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031094.1", "url": "https://www.ensembl.org/id/ENSGALP00010031094.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:770495", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770495", "resource": "KEGG Pathway" }, { "id": "R-GGA-9955298", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9955298", "resource": "Reactome", "description": "SLC-mediated transport of organic anions" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 11, "go_terms": [ { "name": "solute:sodium symporter activity", "id": "GO:0015370", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015370", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "alpha-ketoglutarate transmembrane transporter activity", "id": "GO:0015139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "citrate transmembrane transporter activity", "id": "GO:0015137", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015137", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "high-affinity sodium:dicarboxylate symporter activity", "id": "GO:0015362", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015362", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "sodium:dicarboxylate symporter activity", "id": "GO:0017153", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017153", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "glutathione transmembrane transporter activity", "id": "GO:0034634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "succinate transmembrane transporter activity", "id": "GO:0015141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015141", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "EKC/KEOPS complex", "id": "GO:0000408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "citrate transport", "id": "GO:0015746", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015746", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" }, { "name": "succinate transmembrane transport", "id": "GO:0071422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071422", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": 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"A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-433101", "name": "NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [ "R-ALL-433123" ], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZQT5-1" ], "evidence": [ { "id": "R-GGA-433101", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-433101" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-433123", "participant_name": "SUCCA [extracellular region]", "crossref": [ { "id": "30031", "database": "ChEBI", "url": "" }, { "id": "ZINC000000895030", "database": "ZINC", "url": "" }, { "id": "C00042", "database": "COMPOUND", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] } ] }, { "uniprot_ac": "A0A3Q2TWZ8", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { 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"activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": 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"ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", 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"R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZML0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZML0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZML0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZML0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZND7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZND7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0E5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0E5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0F0", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A0F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0F0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPLGMRPRTLRGHFRSCGCRASQSQTAARRMVTSALPWSPWELCRPLDFREWRAVMIDGLHIQSSARWEKMARPPSGTSQRLAGLSPGAPNETGGAELGGVIGSGAANQQRPLFRLHVGSGERKMEALILEPSLYTVKAVIILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSHENELMLTAVLNCLFDSLSQMLRTWRSGRCWRTWRGSSWLWMRSWMEGERLCAPPVGVPPSPGCWGGGWGADSALLPPPPPHVGSSPPFTALSWRATHSKWCTAWQCGARMCPSQSRQFLRCCSRRRSRSSGRYCANAGPPPGPPLHPKKHTVPPPLLCAASSLPVPFPPPGDAHVGRWGHGDTTHGGGAQCHPHPPKIAVQAQTSSVYWGKAGWGTDRQTWGG", "length": 432, "header": "tr|A0A8V0ZQ56-1|A0A8V0ZQ56_CHICK Isoform 1 of Zeta-coat protein OS=Gallus gallus OX=9031 GN=COPZ1 PE=3 SV=1 CANONICAL=A0A8V0ZQ56-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZML0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56/entry#A0A8V0ZML0-1", "sequence": { "sequence": "MTPLGMRPRTLRGHFRSCGCRASQSQTAARRMVTSALPWSPWELCRPLDFREWRAVMIDGLHIQSSARWEKMARPPSGTSQRLAGLSPGAPNETGGAELGGVIGSGAANQQRPLFRLHVGSGERKMEALILEPSLYTVKAVIILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSHENELMLTAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVVLESDPQQVVHRVAVRGEDVPLTEQTVSQVLQSAKEQIKWSLLR", "length": 302, "header": "tr|A0A8V0ZML0-1|A0A8V0ZQ56_CHICK Computationally mapped isoform of Zeta-coat protein OS=Gallus gallus OX=9031 GN=COPZ1 PE=3 SV=1 CANONICAL=A0A8V0ZQ56-1" }, "locus": { "chromosome": "34", "start_pos": 755906, "end_pos": 751584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054573.1", "url": "https://www.ensembl.org/id/ENSGALT00010054573.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032962.1", "url": "https://www.ensembl.org/id/ENSGALP00010032962.1" } ] } }, { "isoform_ac": "A0A8V0ZND7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56/entry#A0A8V0ZND7-1", "sequence": { "sequence": "MTPLGMRPRTLRGHFRSCGCRASQSQTAARRMVTSALPWSPWELCRPLDFREWRAVMIDGLHIQSSARWEKMARPPSGTSQRLAGLSPGAPNETGGAELGGVIGSGAANQQRPLFRLHVGSGERKMEALILEPSLYTVKAVIILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSHENELMLTAVLNCLFDSLSQMLRTWRSGRCWRTWRGSSWLWMRSWMEALSWRATHSKWCTAWQCGARMCPSQSRQFLRCCSRRRSRSSGRYCANAGPPPGPPLHPKKHTVPPPLLCAASSLPVPFPPPGDAHVGRWGHGDTTHGGGAQCHPHPPKIAVQAQTSSVYWGKAGWGTDRQTWGG", "length": 389, "header": "tr|A0A8V0ZND7-1|A0A8V0ZQ56_CHICK Computationally mapped isoform of Zeta-coat protein OS=Gallus gallus OX=9031 GN=COPZ1 PE=3 SV=1 CANONICAL=A0A8V0ZQ56-1" }, "locus": { "chromosome": "34", "start_pos": 755906, "end_pos": 751319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054581.1", "url": "https://www.ensembl.org/id/ENSGALT00010054581.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032969.1", "url": "https://www.ensembl.org/id/ENSGALP00010032969.1" } ] } }, { "isoform_ac": "A0A8V0ZQ56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56/entry#A0A8V0ZQ56-1", "sequence": { "sequence": "MTPLGMRPRTLRGHFRSCGCRASQSQTAARRMVTSALPWSPWELCRPLDFREWRAVMIDGLHIQSSARWEKMARPPSGTSQRLAGLSPGAPNETGGAELGGVIGSGAANQQRPLFRLHVGSGERKMEALILEPSLYTVKAVIILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSHENELMLTAVLNCLFDSLSQMLRTWRSGRCWRTWRGSSWLWMRSWMEGERLCAPPVGVPPSPGCWGGGWGADSALLPPPPPHVGSSPPFTALSWRATHSKWCTAWQCGARMCPSQSRQFLRCCSRRRSRSSGRYCANAGPPPGPPLHPKKHTVPPPLLCAASSLPVPFPPPGDAHVGRWGHGDTTHGGGAQCHPHPPKIAVQAQTSSVYWGKAGWGTDRQTWGG", "length": 432, "header": "tr|A0A8V0ZQ56-1|A0A8V0ZQ56_CHICK Isoform 1 of Zeta-coat protein OS=Gallus gallus OX=9031 GN=COPZ1 PE=3 SV=1 CANONICAL=A0A8V0ZQ56-1" }, "locus": { "chromosome": "34", "start_pos": 755906, "end_pos": 751319, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054578.1", "url": "https://www.ensembl.org/id/ENSGALT00010054578.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032966.1", "url": "https://www.ensembl.org/id/ENSGALP00010032966.1" } ] } }, { "isoform_ac": "A0A8V0ZUV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56/entry#A0A8V0ZUV8-1", "sequence": { "sequence": "MTALPGGAPADPQPSHWALWGGPAFAPPPPALSHGRPHRCVRIRTAPHSPSMVPHDPESPRSDSGEAKGQRASQSQTAARRMVTSALPWSPWELCRPLDFREWRAVMIDGLHIQSSARWEKMARPPSGTSQRLAGLSPGAPNETGGAELGGVIGSGAANQQRPLFRLHVGSGERKMEALILEPSLYTVKAVIILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSHENELMLTAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVVLESDPQQVVHRVAVRGEDVPLTEQTVSQVLQSAKEQIKWSLLR", "length": 352, "header": "tr|A0A8V0ZUV8-1|A0A8V0ZQ56_CHICK Computationally mapped isoform of Zeta-coat protein OS=Gallus gallus OX=9031 GN=COPZ1 PE=3 SV=1 CANONICAL=A0A8V0ZQ56-1" }, "locus": { "chromosome": "34", "start_pos": 756140, "end_pos": 751584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054575.1", "url": "https://www.ensembl.org/id/ENSGALT00010054575.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032964.1", "url": "https://www.ensembl.org/id/ENSGALP00010032964.1" } ] } }, { "isoform_ac": "A0A8V1A0E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56/entry#A0A8V1A0E5-1", "sequence": { "sequence": "MVPHDPESPRSDSGEAKGQRASQSQTAARRMVTSALPWSPWELCRPLDFREWRAVMIDGLHIQSSARWEKMARPPSGTSQRLAGLSPGAPNETGGAELGGVIGSGAANQQRPLFRLHVGSGERKMEALILEPSLYTVKAVIILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKTHRTDSEIALLEGLTVVYKSSIDLYFYVIGSSHENELMLTAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVVLESDPQQVVHRVAVRGEDVPLTEQTVSQVLQSAKEQIKWSLLR", "length": 301, "header": "tr|A0A8V1A0E5-1|A0A8V0ZQ56_CHICK Computationally mapped isoform of Zeta-coat protein OS=Gallus gallus OX=9031 GN=COPZ1 PE=3 SV=1 CANONICAL=A0A8V0ZQ56-1" }, "locus": { "chromosome": "34", "start_pos": 755987, "end_pos": 751584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056935.1", "url": "https://www.ensembl.org/id/ENSGALT00010056935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034621.1", "url": "https://www.ensembl.org/id/ENSGALP00010034621.1" } ] } }, { "isoform_ac": "A0A8V1A0F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56/entry#A0A8V1A0F0-1", "sequence": { "sequence": "MTPLGMRPRTLRGHFRSCGCRASQSQTAARRMVTSALPWSPWELCRPLDFREWRAVMIDGLHIQSSARWEKMARPPSGTSQRLAGLSPGAPNETGGAELGGVIGSGAANQQRPLFRLHVGSGERKMEALILEPSLYTVKAVIILDNDGDRLFAKLMLTAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIVDGGVVLESDPQQVVHRVAVRGEDVPLTEQTVSQVLQSAKEQIKWSLLR", "length": 244, "header": "tr|A0A8V1A0F0-1|A0A8V0ZQ56_CHICK Computationally mapped isoform of Zeta-coat protein OS=Gallus gallus OX=9031 GN=COPZ1 PE=3 SV=1 CANONICAL=A0A8V0ZQ56-1" }, "locus": { "chromosome": "34", "start_pos": 755906, "end_pos": 751584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056943.1", "url": "https://www.ensembl.org/id/ENSGALT00010056943.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034626.1", "url": "https://www.ensembl.org/id/ENSGALP00010034626.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-GGA-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56" } ], "pmid": "" }, { "name": "COPI vesicle coat", "id": "GO:0030126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56" } ], "pmid": "" }, { "name": "retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "id": "GO:0006890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006890", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56" } ], "pmid": "" }, { "name": "intra-Golgi vesicle-mediated transport", "id": "GO:0006891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQ56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ56" }, { "id": "PF01217", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP complex mu/sigma subunit", "eco_id": "ECO_0000259", "start_pos": 137, "end_pos": 231, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MZT2B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZPM5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "768838", "url": "https://www.ncbi.nlm.nih.gov/gene/768838", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768838", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768838", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MCAGQRA", "url": "https://omabrowser.org/oma/group/MCAGQRA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP57", "url": "https://www.orthodb.org/?gene=A0A8V0ZP57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPM5", "url": "https://www.orthodb.org/?gene=A0A8V0ZPM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28578", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28578", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28578:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28578:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-380270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZP57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGAALGKAAVAAAARPRRKVLSAEEAELFELAQAAGSGLDPEVFKVLLDLLRMNVAPLAVFQVLKSMCAGQRLPAGPESAPPAAPPADSRGWNMPARLVDALCHWITHGLLRQEDCAHQATVLVFCHVCAEKAGLKLTLSWCLVLLTEVGCVWFLGGFFFFFFFPRSFCCIKTQSSS", "length": 178, "header": "tr|A0A8V0ZPM5-1|A0A8V0ZPM5_CHICK Isoform 1 of Mitotic spindle organizing protein 2B OS=Gallus gallus OX=9031 GN=MZT2B PE=1 SV=1 CANONICAL=A0A8V0ZPM5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP57-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM5/entry#A0A8V0ZP57-1", "sequence": { "sequence": "MSGAALGKAAVAAAARPRRKVLSAEEAELFELAQAAGSGLDPEVFKVLLDLLRMNVAPLAVFQVLKSMCAGQRLPAGPESAPPAAPPADSRGRTKSSSAVSGTQVLVERSSREGSAQRMPRQPSASRLQKAGASGKNSGSNNS", "length": 143, "header": "tr|A0A8V0ZP57-1|A0A8V0ZPM5_CHICK Computationally mapped isoform of Mitotic spindle organizing protein 2B OS=Gallus gallus OX=9031 GN=MZT2B PE=1 SV=1 CANONICAL=A0A8V0ZPM5-1" }, "locus": { "chromosome": "10", "start_pos": 878327, "end_pos": 870236, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054066.1", "url": "https://www.ensembl.org/id/ENSGALT00010054066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032597.1", "url": "https://www.ensembl.org/id/ENSGALP00010032597.1" } ] } }, { "isoform_ac": "A0A8V0ZPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM5/entry#A0A8V0ZPM5-1", "sequence": { "sequence": "MSGAALGKAAVAAAARPRRKVLSAEEAELFELAQAAGSGLDPEVFKVLLDLLRMNVAPLAVFQVLKSMCAGQRLPAGPESAPPAAPPADSRGWNMPARLVDALCHWITHGLLRQEDCAHQATVLVFCHVCAEKAGLKLTLSWCLVLLTEVGCVWFLGGFFFFFFFPRSFCCIKTQSSS", "length": 178, "header": "tr|A0A8V0ZPM5-1|A0A8V0ZPM5_CHICK Isoform 1 of Mitotic spindle organizing protein 2B OS=Gallus gallus OX=9031 GN=MZT2B PE=1 SV=1 CANONICAL=A0A8V0ZPM5-1" }, "locus": { "chromosome": "10", "start_pos": 878327, "end_pos": 876403, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054065.1", "url": "https://www.ensembl.org/id/ENSGALT00010054065.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032596.1", "url": "https://www.ensembl.org/id/ENSGALP00010032596.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768838", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768838", "resource": "KEGG Pathway" }, { "id": "R-GGA-380270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380270", "resource": "Reactome", "description": "Recruitment of mitotic centrosome proteins and complexes" }, { "id": "R-GGA-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" } ], "orthologs": [ { "uniprot_canonical_ac": "A5PJV8-1", "protein_name": "Mitotic-spindle organizing protein 2", "gene_name": "MZT2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAGAGPGPGPGAPPGLEAALQKLALRRKKVLSAEEMELFELAQAAGGAMDPDVFKILVDLLKLNVAPLAVFQMLKSMCAGQRVASDSQDPTAAPLPTPSVPETRGRNKGGGALGGGPALAERGGRDGPGQRMPRQPSASRLPKGGGPGRSPPRSGT", "length": 158 }, "evidence": [ { "id": "A0A8V0ZPM5", "url": "https://omabrowser.org/oma/group/A0A8V0ZPM5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6DC17-1", "protein_name": "Mitotic-spindle organizing protein 2", "gene_name": "mzt2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPSAPDSPSLSVNVSGNVQKYSIKKKKVLNAEETELFELTQAAGVVIDQEVFKIIVDLLKMNVAPLAVFQTLKTMCAGQKVSETSTGDASSTSHTTAVPTESRVRSKMSSGQGEKSARESSSQRVPRQVSATRGQKSTKSSGSSSSSSQLTSN", "length": 153 }, "evidence": [ { "id": "A0A8V0ZPM5", "url": "https://omabrowser.org/oma/group/A0A8V0ZPM5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P582-1", "protein_name": "Mitotic-spindle organizing protein 2A", "gene_name": "MZT2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAQGVGPGPGSAAPPGLEAARQKLALRRKKVLSTEEMELYELAQAAGGGIDPDVFKILVDLLKLNVAPLAVFQMLKSMCAGQRLASEPQDPAAVSLPTSSVPETRGRDKGSAALGGVLALAERSNHEGSSQRMPRQPSATRLPKGGGPGKSPTQGST", "length": 158 }, "evidence": [ { "id": "A0A8V0ZPM5", "url": "https://omabrowser.org/oma/group/A0A8V0ZPM5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM5" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM5" } ], "pmid": "" } ] } ] }, "pro_annotation": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZPX8" } ] } ], "protein_names": [ { "name": "Sushi domain containing 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SUSD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX8", "locus": { "chromosome": "15", "start_pos": 7832218, "end_pos": 7850555, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023983", "url": "https://www.ensembl.org/id/ENSGALG00010023983" } ] } } ], "crossref": [ { "id": "A0A8V0ZPX8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416922", "url": "https://www.ncbi.nlm.nih.gov/gene/416922", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13802", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13802", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13802:SF63", "url": 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"categories": [ "Protein" ] }, { "id": "A0A8V0ZV60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZV60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZV60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"chromosome": "15", "start_pos": 7850188, "end_pos": 7834266, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058389.1", "url": "https://www.ensembl.org/id/ENSGALT00010058389.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035479.1", "url": "https://www.ensembl.org/id/ENSGALP00010035479.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 221, "start_aa": "Thr", "end_pos": 221, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr221", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], 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"end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 221 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 512, "end_pos": 514 }, { "start_pos": 544, "end_pos": 546 }, { "start_pos": 561, "end_pos": 563 }, { "start_pos": 586, "end_pos": 588 }, { "start_pos": 639, "end_pos": 641 }, { "start_pos": 660, "end_pos": 662 }, { "start_pos": 684, "end_pos": 686 }, { "start_pos": 707, "end_pos": 709 }, { "start_pos": 752, "end_pos": 754 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZP15-1", "uniprot_ac": "A0A8V0ZP15", "uniprot_id": "A0A8V0ZP15_CHICK", "mass": { "chemical_mass": 127395.0, "monoisotopic_mass": 127395.0 }, "refseq": { "ac": "XP_025009651", "name": "AP-4 complex subunit epsilon-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009651" }, "gene_names": [ { "name": "AP4E1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15" } ] }, { "name": "AP4E1", "type": "synonym", "evidence": [ { "id": "XP_025009651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009651" } ] } ], "protein_names": [ { "name": "AP-4 complex subunit epsilon-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025009651", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009651" } ] }, { "name": "Adaptor related protein complex 4 subunit epsilon 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZP15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025009651.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025009651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009651" } ] }, { "annotation": "Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZWH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH6#function" }, { "database": "UniProtKB", "id": "PIRNR037097", "url": "https://www.uniprot.org/uniprotkb/PIRNR037097#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AP4E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15", "locus": { "chromosome": "10", "start_pos": 9168858, "end_pos": 9150585, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022573", "url": "https://www.ensembl.org/id/ENSGALG00010022573" } ] } } ], "crossref": [ { "id": "A0A8V0ZP15", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP15", "database": "AlphaFoldDB", "categories": [] }, { "id": "415425", "url": "https://www.ncbi.nlm.nih.gov/gene/415425", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415425", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415425", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ADNNMEI", "url": "https://omabrowser.org/oma/group/ADNNMEI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP15", "url": "https://www.orthodb.org/?gene=A0A8V0ZP15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWH6", "url": "https://www.orthodb.org/?gene=A0A8V0ZWH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01602", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01602", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14807", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14807", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-432720", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432720", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025009651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025009651", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDVVERTLGVLPALLGQHEPGAGPGGAGGPHRLSASSRLGSLIRNITALTSKHEEEKLIQQEITSLKAMVSAPTTSLRLMKECMVRLIYCEMLGYESSFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHENHELLLLLVNTVVKDLQSTNLVEVSMALTIVSQIFPREMIPAVLPLIEDKLQHSKEIIRRKAVQALYKFYLIAPNQVQHIHDKFRKALCDRDVGVMAASLHIYLEMIKENSSGYKDLTESFVIILKQVVGGKLPIDFNYHSVPAPWLQIQLLRILGLLGKDDPRTSELMYDVLEESLRRAEINHNITYAILFECVQTIYTIYPKSELLEKAAKCIGKFVLSPQINLKYLGLKALTCVIQQDPNLALEHQMTIIECLDHPDPIIKRETLEILYRITNGHNVVVIVQKMLDYLKETKEEYAIITLAGKIAELAEKYAPNNEWFIQTMNAVFSVGGDVLYPDIPNNFLRLLAEGFDDGKEDKQLRTYAVRSYLALLEEENVFYPQKFLQVMSWVLGEYSSLATDVDPETILTRLHNLLKKTFVTSETKAWIMAAVTKIASRASFSKTVDKLIQEFSSSLDTCMRQHTFELKHLCEDKVLMKGLLPFDASCNDMVVDASLSFLDEFVAEGLGQGAAPYKPHHQRQEEKLSQEKALNFEPYGLSFASSVSSSGIAGRQSPTGLSFGSDTSGNSTEMGHKETNTLKLEGVRKLWGKEGYLPKKESKVGKEDEPQTVSCSSLLARRVAETPVSKSDQVSSLSEEEKEKQQLASTLFVGLGSNANVSLMGKVDLSTQKFKRKSKVDKAQSNEEALNMQNSAASDFGPLVDTVPITKEDCDGDKHTTLRKPSLCSSDTVGETLQSVKKPGLDDKLSDSRLSPLSLFADSNIEILQPSPSSQCENANKTVLLPSLAEELEELPHSEVAELCQSDALALYLCKVWKDDSLLLVVFVSNKNPSALNAVNVVFEKEQHFQILESPACQFPVIEAQSVGHCQKCVRMDKLCTQGVISGFVNYQSEMETHLEFSIPLSLLDFIRPMKMTTEDFGKLWLSLSNDVKQNIKMPSSQDSISAALSVLHQKLKLHIVDIIGNEGILACQLLPSVPCLLHCRTHSGMLALWFRSPCSALPDGLLYQCQKVMEES", "length": 1144, "header": "tr|A0A8V0ZP15-1|A0A8V0ZP15_CHICK Isoform 1 of Adaptor related protein complex 4 subunit epsilon 1 OS=Gallus gallus OX=9031 GN=AP4E1 PE=1 SV=1 CANONICAL=A0A8V0ZP15-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15/entry#A0A8V0ZP15-1", "sequence": { "sequence": "MSDVVERTLGVLPALLGQHEPGAGPGGAGGPHRLSASSRLGSLIRNITALTSKHEEEKLIQQEITSLKAMVSAPTTSLRLMKECMVRLIYCEMLGYESSFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHENHELLLLLVNTVVKDLQSTNLVEVSMALTIVSQIFPREMIPAVLPLIEDKLQHSKEIIRRKAVQALYKFYLIAPNQVQHIHDKFRKALCDRDVGVMAASLHIYLEMIKENSSGYKDLTESFVIILKQVVGGKLPIDFNYHSVPAPWLQIQLLRILGLLGKDDPRTSELMYDVLEESLRRAEINHNITYAILFECVQTIYTIYPKSELLEKAAKCIGKFVLSPQINLKYLGLKALTCVIQQDPNLALEHQMTIIECLDHPDPIIKRETLEILYRITNGHNVVVIVQKMLDYLKETKEEYAIITLAGKIAELAEKYAPNNEWFIQTMNAVFSVGGDVLYPDIPNNFLRLLAEGFDDGKEDKQLRTYAVRSYLALLEEENVFYPQKFLQVMSWVLGEYSSLATDVDPETILTRLHNLLKKTFVTSETKAWIMAAVTKIASRASFSKTVDKLIQEFSSSLDTCMRQHTFELKHLCEDKVLMKGLLPFDASCNDMVVDASLSFLDEFVAEGLGQGAAPYKPHHQRQEEKLSQEKALNFEPYGLSFASSVSSSGIAGRQSPTGLSFGSDTSGNSTEMGHKETNTLKLEGVRKLWGKEGYLPKKESKVGKEDEPQTVSCSSLLARRVAETPVSKSDQVSSLSEEEKEKQQLASTLFVGLGSNANVSLMGKVDLSTQKFKRKSKVDKAQSNEEALNMQNSAASDFGPLVDTVPITKEDCDGDKHTTLRKPSLCSSDTVGETLQSVKKPGLDDKLSDSRLSPLSLFADSNIEILQPSPSSQCENANKTVLLPSLAEELEELPHSEVAELCQSDALALYLCKVWKDDSLLLVVFVSNKNPSALNAVNVVFEKEQHFQILESPACQFPVIEAQSVGHCQKCVRMDKLCTQGVISGFVNYQSEMETHLEFSIPLSLLDFIRPMKMTTEDFGKLWLSLSNDVKQNIKMPSSQDSISAALSVLHQKLKLHIVDIIGNEGILACQLLPSVPCLLHCRTHSGMLALWFRSPCSALPDGLLYQCQKVMEES", "length": 1144, "header": "tr|A0A8V0ZP15-1|A0A8V0ZP15_CHICK Isoform 1 of Adaptor related protein complex 4 subunit epsilon 1 OS=Gallus gallus OX=9031 GN=AP4E1 PE=1 SV=1 CANONICAL=A0A8V0ZP15-1" }, "locus": { "chromosome": "10", "start_pos": 9167434, "end_pos": 9150631, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054940.1", "url": "https://www.ensembl.org/id/ENSGALT00010054940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033216.1", "url": "https://www.ensembl.org/id/ENSGALP00010033216.1" } ] } }, { "isoform_ac": "A0A8V0ZWH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15/entry#A0A8V0ZWH6-1", "sequence": { "sequence": "MCSLFFFLIVSCPKKLHRIKFNSFLGGRKINPAGNNQFESNGFCPHHLTCYLAVSLFLHENHELLLLLVNTVVKDLQSTNLVEVSMALTIVSQIFPREMIPAVLPLIEDKLQHSKEIIRRKAVQALYKFYLIAPNQVQHIHDKFRKALCDRDVGVMAASLHIYLEMIKENSSGYKDLTESFVIILKQVVGGKLPIDFNYHSVPAPWLQIQLLRILGLLGKDDPRTSELMYDVLEESLRRAEINHNITYAILFECVQTIYTIYPKSELLEKAAKCIGKFVLSPQINLKYLGLKALTCVIQQDPNLALEHQMTIIECLDHPDPIIKRETLEILYRITNGHNVVVIVQKMLDYLKETKEEYAIITLAGKIAELAEKYAPNNEWFIQTMNAVFSVGGDVLYPDIPNNFLRLLAEGFDDGKEDKQLRTYAVRSYLALLEEENVFYPQKFLQVMSWVLGEYSSLATDVDPETILTRLHNLLKKTFVTSETKAWIMAAVTKIASRASFSKTVDKLIQEFSSSLDTCMRQHTFELKHLCEDKVLMKGLLPFDASCNDMVVDASLSFLDEFVAEGLGQGAAPYKPHHQRQEEKLSQEKALNFEPYGLSFASSVSSSGIAGRQSPTGLSFGSDTSGNSTEMGHKETNTLKLEGVRKLWGKEGYLPKKESKVGKEDEPQTVSCSSLLARRVAETPVSKSDQVSSLSEEEKEKQQLASTLFVGLGSNANVSLMGKVDLSTQKFKRKSKVDKAQSNEEALNMQNSAASDFGPLVDTVPITKEDCDGDKHTTLRKPSLCSSDTVGETLQSVKKPGLDDKLSDSRLSPLSLFADSNIEILQPSPSSQCENANKTVLLPSLAEELEELPHSEVAELCQSDALALYLCKVWKDDSLLLVVFVSNKNPSALNAVNVVFEKEQHFQILESPACQFPVIEAQSVGHCQKCVRMDKLCTQGVISGFVNYQSEMETHLEFSIPLSLLDFIRPMKMTTEDFGKLWLSLSNDVKQNIKMPSSQDSISAALSVLHQKLKLHIVDIIGNEGILACQLLPSVPCLLHCRTHSGMLALWFRSPCSALPDGLLYQCQKVMEES", "length": 1074, "header": "tr|A0A8V0ZWH6-1|A0A8V0ZP15_CHICK Computationally mapped isoform of Adaptor related protein complex 4 subunit epsilon 1 OS=Gallus gallus OX=9031 GN=AP4E1 PE=1 SV=1 CANONICAL=A0A8V0ZP15-1" }, "locus": { "chromosome": "10", "start_pos": 9167434, "end_pos": 9151186, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054937.1", "url": "https://www.ensembl.org/id/ENSGALT00010054937.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033215.1", "url": "https://www.ensembl.org/id/ENSGALP00010033215.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415425", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415425", "resource": "KEGG Pathway" }, { "id": "R-GGA-432720", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432720", "resource": "Reactome", "description": "Lysosome Vesicle Biogenesis" }, { "id": "R-GGA-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IQI7-1", "protein_name": "AP-4 complex subunit epsilon", "gene_name": "ap4e1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDVVEKTLTALPSLFDSQTGAAKISNRLKQLIKSITELTSKHDEESLIKQELSAMKEQVSAPSTSMKQMREIMVRSMYCEMLGYDASFSYIHAIKLAQQGGVMEKRVGYLAVSLFLSEGHELLLLLVNTVLKDLQSTNLIEACMALTVVAQVFPKDMIPAVLPLVEDKLSHPKEIIRRKAVLALYKFYLIAPNQVQHIHAKFRKALCDKDPGVMTSSLHIYLQLIQESPDAYKDLTGSFVTILKQVVGGKLPLDFNYHSVPAPWLQIQLLRILSLLGRDDQSTSELMYEVLDESLRRAEMNHNITYAILFECVKAVYTIHPKAELLEKAARCIGNFVLSPKINLKYLGLKALTYVVQHDAKLALQHQMTIIECLDHSDFTIKRETLELLFRITNAQNVSVIVEKMLDFLRSCSDEHTIIHLAGKVAELAEKFAPDNSWFIQTMNDVFSIGGDLLQQDISNNFLRLLAEGSESKEEDDQLRLYAVDSYLTLLNGDASHLPQRFIQVMSWVVGEYSHLQECVDQSEVIRLLMKLLEQKSVSSETRVWILSALTKISDGQTDLILELAESISSSQDTILRQQAHELRHLSLDSKLHEWVLPRGAAWDDMEVDSSLSFLDGFVSEALAAGAAPYKPPHQRQEELCEQRALNLEPYSFSLPVSLSSCSITDRHSPTLLSVSSGLSGNSTELSQKAGASTLILEGVKRVWGKDGYLPQKETAVTASPVDEPSAAVQPVGQQEAAERLEPQPEPSTQTNDKQQLASSLFVGLSTQSSTSLLGKSEAPPPRFRKKPRPHGSSLSSSSSSGTSEKSSSSRTSHNTTDSFLYGSLLEEEPAGFDHTPKSITANGLGQNKDVKEDRRTNTSQILGSDMVIVRPNTIQHNPSTSSDLTTLLPADLKDLPHSDVISLTSDPSLSVSSCRVFRDEALLLVIFISNSTETDIRDVAVQLNCDQLETVSLRGNIVDCLEGRSVSVCHYALLMDDPHTNVSFTGSVSYQIQPGHTNTLSFSGTLSTADFIRPLVVTTDEYGKLWLSLSHDVKQNLKLLTDAGDPLQTTLNALKDTLQLHIVDIIGSEGIVACRLLSGAPCLLHCRVNGSALAMWLRSPLPALPDCILYHCQRALAQH", "length": 1121 }, "evidence": [ { "id": "A0A8V0ZP15", "url": "https://omabrowser.org/oma/group/A0A8V0ZP15/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0M9P9-1", "protein_name": "AP-4 complex subunit epsilon", "gene_name": "Ap4e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDMVERTLTALPGLFLQNQLGGPAASRAPFFSRLGGLIRGVTALSSKHEEEKLIQQELSSLKATVSAPTTTLKMMKECMVRLIYCEMLGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMALTVVSQIFPREMIPAVLPLIEEKLQHSKEIIRRKAVLALYKFYLIAPNQVQHIHTKFRKALCDRDVGVMAASLHIYLRMIKENSSGYKDLTESFVTILKQVVGGKLPVEFSYHSVPAPWLQIQLLRILGLLGKDDERTSELMYDVLDESLRRAELNHNVTYAILFECVHTIYSIYPKSELLEKAAKCIGKFVLSPKINLKYLGLKALTYVIQQDPSLALQHQITIIECLDHPDPIIKRETLELLYRITNAQNVVVIVQKMLEYLHQSKEEYIIINLVGKIAELAEKYAPDNVWFIQTMNAVFSVGGDVMHPDILSNFLRLLAEGFDDETEDQQLRLYAVQSYLTLLDMENTFYPQRFLQVMSWVLGEYSYLLDRESPEAVMTRLYKLLRSDSISSETKAWLFAAVTKLTPQAHSSPIVENLIQEFTVSLNTCLRQHAFELKHLHENEELMKSLLQSAQNCDDIMADASLSFLDGFVAEGLSQGAAPYKPRHQRQEEQLSQEKVLNFEPYGLSFSSSGFTGRQSPAGVSLGSDISGNSAETGLKEAGSLKMDGIKKLWGKEGYLPKKESGAADKLEAAHAPAESAMMENVDQAMTRKDQAQGHTPSTEEKEKQLLASSLFVGLGPENTINLLGKADVVSYKFRRKSKPKVAQSDKMPSAHAAPSSTLSPVSDVAGGDEDSLSAADRGDGELGSELLGSESVLELPSVENLSSVSLPVSSLFAGNDMEVFHPPSSSATSAVKEVSLAALLEETPECRRSALVEICSNETVAVSSYKVWKDECLLLVCSVTSKTDSEFTDAQLEIFPLENFKIIEQPGCPSPVMEAESTKSFQYGVQMESPCVEGTLSGFIKYQMMDTHPVQLEFSMNLSLLDFIRPLKISTEDFGKLWLSFANDVKQNIKISEPRVALASVLTELQQKLRLCVVDVIGSEGLLACKLLPSTPCILHCRVHADVVALWFRSSSSVLSDCLSCHCQKVMQTS", "length": 1130 }, "evidence": [ { "id": "A0A8V0ZP15", "url": "https://omabrowser.org/oma/group/A0A8V0ZP15/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80V94-1", "protein_name": "AP-4 complex subunit epsilon-1", "gene_name": "Ap4e1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDMVERTLTALPGLFLQNQLGGPAASRAPFFSRLGGLIRGVTALSSKHEEEKLIQQELSSLKATVSAPTTTLKTMKECMVRLIYCEMLGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMALTVVSQIFPREMIPAVLPLIEDKLQHSKEIIRRKAVLALYKFYLIAPNQVQHIHTKFRKALCDRDVGVMAASLHIYLRMIKENASGYKDLTESFVTILKQVVGGKLPVEFSYHSVPAPWLQIQLLRILGLLGKDDERTSELMYDVLDESLRRAELNHNVTYAILFECVHTIYSIYPKSELLEKAAKCIGKFVLSPKINLKYLGLKALTYVIQQDPSLALQHQITIIECLDHPDPIIKRETLELLYRITNAQNVVVIVQKMLEYLHQSKEEHIIISLVGRIAELAEKYAPDNVWFIQTMNAVFSVGGDVMHPDILSNFLRLLAEGFDDETEDQQLRLYAVQSYLTLLDMENTFYPQRFLQVMSWVLGEYSYLLDKESPEEVITRLYKLLMSDSISSETKAWLFAAVTKLTPQAHSSPLVEKLIQEFTVSLNTCLRQHAFELKHLHENTELMKSLLQGAQNCEDIVADASLSFLDGFVAEGLSQGAAPYKPHHQRQEEQLSQEKVLNFEPYGLSFSSSGFTGRQSPAGISLGSDISGNSAETGLKETSSLKMEGIKKLWGKEGYLPKKESGTGDKPEASHVPAEGATVENVDQATTRKDQAQGHIPSTEEKEKQLLASSLFVGLGPENTVDLLGKADVVSHKFRRKSKLKVAQSDKTPSAPTAPCSALSLGSDVAGGDEDGLSAVDRGDGELSSELFRSESLSGPPSAEKLESVSLPVPSLFADNNMEVFNPPSSSATSTVKEETPECRHSGLVEICSNEAVSVSSYKVWRDDCLLVIWAVTSKTDSEFTDAQLEIFPVENFKIIEQPECSSPVIETERTKSFQYSVQMESPCIEGTLSGFIKYQMMDTHSVQLEFSMNLPLLDFIRPLKISTEDFGKLWLSFANDVKQTIKISEPGVALTSVLTELQQNLRLRVIDVIGNEGLLACKLLPSTPCVLHCRVHADAVALWFRSSSSVLSDYLSCHCQKVMQTS", "length": 1122 }, "evidence": [ { "id": "A0A8V0ZP15", "url": "https://omabrowser.org/oma/group/A0A8V0ZP15/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8L7A9-1", "protein_name": "AP-4 complex subunit epsilon", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEQLKTIGRELAMGSQGGFGQSKEFLDLVKSIGEARSKAEEDRIVLSEVDILKRRLLEPDIPKRKMKEYIIRLVYIEMLGHDASFGYIYAVKMTHDDNLLLKRTGYLAVTLFLNEDHDLIILIVNTIQKDLRSDNYLVVCAALNAICRLINEETIPAVLPQVVELLNHQKEAVRKKAIMALHRFHRKSPSSVSHLVSNFRKRLCDNDPGVMGATLCPLFDLISEDVNSYKDLVSSFVSILKQVTERRLPKSYDYHQMPAPFIQIKLLKIMALLGSGDKNASDIMSMVLGDLFRKCDSSTNIGNAILYECIRCISCILPNPKLLEAAADAISKFLKSDSHNLKYMGIDGLGRLIKISPDIAEQHQLAVIDCLEDPDDTLKRKTFELLYKMTKSSNVEVIVDRMIDYMISINDNHYKTEIASRCVELAEQFAPSNQWFIQIMNKVFEHAGDLVNIKVAHNLMRLIAEGFGEDDDDADSKLRLSAVESYLQLISEPKLPSLFLQVISWVLGEYGTADGKYSASYISGKLCDVADAYSSDETVKGYAVSALMKIYAFEIASGRKVDVLPECQSLIEELLASHSTDLQQRAYELQALLALDARAVETILPLDASCEDIEVDKDLSFLNGYIQQAIESGAQPYISERERSGMFETTDYHPQDHHEVPTHALRFEAYELPKPSVPPQASNELVPVPEPSYYSESHQPISTSLVSERESSEIKLRLDGVKQKWGRPSYQSTTAASSTTPQAANGISTHSDAGVGSSSSKPRSSYEPKKPEIDPEKQRLAASLFGGSSSRTDKRSSSGGHKPAKGTANKTATVPKENQTPVQPPPDLLDFGEPTATTATAMDPFKELEGLMDSSSQDGGSSDVMGLYSDAAPVTTTTSVDSLLSELSDSSKGNSRTYQPQTSKGPNTKEALEKDALVRQMGVNPTSQNPTLFKDLLG", "length": 938 }, "evidence": [ { "id": "A0A8V0ZP15", "url": "https://omabrowser.org/oma/group/A0A8V0ZP15/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UPM8-1", "protein_name": "AP-4 complex subunit epsilon-1", "gene_name": "AP4E1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDIVEKTLTALPGLFLQNQPGGGPAAAKASFSSRLGSLVRGITALTSKHEEEKLIQQELSSLKATVSAPTTTLKMMKECMVRLIYCEMLGYDASFGYIHAIKLAQQGNLLEKRVGYLAVSLFLHESHELLLLLVNTVVKDLQSTNLVEVCMALTVVSQIFPCEMIPAVLPLIEDKLQHSKEIVRRKAVLALYKFHLIAPNQVQHIHIKFRKALCDRDVGVMAASLHIYLRMIKENSSGYKDLTGSFVTILKQVVGGKLPVEFNYHSVPAPWLQIQLLRILGLLGKDDQRTSELMYDVLDESLRRAELNHNVTYAILFECVHTVYSIYPKSELLEKAAKCIGKFVLSPKINLKYLGLKALTYVIQQDPTLALQHQMTIIECLDHPDPIIKRETLELLYRITNAQNITVIVQKMLEYLHQSKEEYVIVNLVGKIAELAEKYAPDNAWFIQTMNAVFSVGGDVMHPDIPNNFLRLLAEGFDDETEDQQLRLYAVQSYLTLLDMENVFYPQRFLQVMSWVLGEYSYLLDKETPEEVIAKLYKLLMNDSVSSETKAWLIAAVTKLTSQAHSSNTVERLIHEFTISLDTCMRQHAFELKHLHENVELMKSLLPVDRSCEDLVVDASLSFLDGFVAEGLSQGAAPYKPPHQRQEEKLSQEKVLNFEPYGLSFSSSGFTGRQSPAGISLGSDVSGNSAETGLKETNSLKLEGIKKLWGKEGYLPKKESKTGDESGALPVPQESIMENVDQAITKKDQSQVLTQSKEEKEKQLLASSLFVGLGSESTINLLGKADTVSHKFRRKSKVKEAKSGETTSTHNMTCSSFSSLSNVAYEDDYYSNTLHDTGDKELKKFSLTSELLDSESLTELPLVEKFSYCSLSTPSLFANNNMEIFHPPQSTAASVAKESSLASSFLEETTEYIHSNAMEVCNNETISVSSYKIWKDDCLLMVWSVTNKSGLELKSADLEIFPAENFKVTEQPGCCLPVMEAESTKSFQYSVQIEKPFTEGNLTGFISYHMMDTHSAQLEFSVNLSLLDFIRPLKISSDDFGKLWLSFANDVKQNVKMSESQAALPSALKTLQQKLRLHIIEIIGNEGLLACQLLPSIPCLLHCRVHADVLALWFRSSCSTLPDYLLYQCQKVMEGS", "length": 1137 }, "evidence": [ { "id": "A0A8V0ZP15", "url": "https://omabrowser.org/oma/group/A0A8V0ZP15/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15" } ], "pmid": "" }, { "name": "AP-4 adaptor complex", "id": "GO:0030124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cargo adaptor activity", "id": "GO:0140312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140312", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" }, { "start_pos": 787, "end_pos": 789, "annotation": "n_glycosylation_sequon" }, { "start_pos": 907, "end_pos": 909, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZP15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP15" }, { "id": "SM01356", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01356" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-4 complex subunit epsilon-1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 1039, "end_pos": 1142, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA 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"CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051111", "url": 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZRD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUE5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUH0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWTKCKYACCFSGGMGWPAELSIPLHCESPEAETWQRALGQLPSWAAAELCPRRKAGVITEIRHSMTESLFPLAGTAEFAARRSNQTSLLLSETWSPDTGTSEGRSCSIFPCPGAKGIEKMENRRSSLLRYVHWEAEEEGDEEDDVASGASPSSQMSELEDVQVEMLEKARELFQLCDKDKKGFITKLDMQRLQSELPLTPEQLETVFDSLEQNNNGYLTPVEFSMGLGKLIGINLCQGAGRTDRSSHEETFESGWSDDMDPADDEEKRFCSMMEQLGAAQVFEDPSEVRDLWARLRKERPELLANFEEFLLRVSSYIREVNHEKESMEQALKRKETDHDREVRCLYEEMEQQIRAERERLICQEALRHSRSNLLQKELRSKEQELEKILYRQKKLEHQLQSLNSEQLETRVQNERLRHLNENLLEELEKSKWELEAVKGQLQKLQKEAQNEQEQKDRDVFRVSKNMQKEKQSLLRQLELLREMNKKLRDERDTFEAKKPAPQSKKPLLKKGSVLGSYLLDDKPVKRQLASADLPVTFPMDVAMEEPNRKSCKYFSGNGTWLKTGEGDRTNFAEKNRDQEKWSVRADAEKLKMALKSDADCRKSADGLDDAPLSPRRQPVGTETRLQVLEPASCCPDRIFKVVFVGNSGVGKSSFIHRFCYDRFLADLNATIGIDYQVKSLMVDNTQVALQLWDTAGQERFRSITKQYFRKADGILVMYDITAECSFTAVRNWMSSVQEGIEDGAVVFLLGNKMDTAGRETRSVPKMEGERLAKEYKAVFYECSAMTGYNIMEPMLHMARLLTAQEDRQRENALQLEDVRRKGCCT", "length": 826, "header": "tr|A0A8V0ZRF4-1|A0A8V0ZRF4_CHICK Isoform 1 of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=EFCAB4B PE=1 SV=1 CANONICAL=A0A8V0ZRF4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4/entry#A0A8V0ZRD7-1", "sequence": { "sequence": "MELVFGKRSQENIRSGWSAVGSGWERAGRGIPVPLSSISCTDPPHCLCPALQLWCTSGSFSSACCSIFPCPGAKGIEKMENRRSSLLRYVHWEAEEEGDEEDDVASGASPSSQMSELEDVQVEMLEKARELFQLCDKDKKGFITKLDMQRLQSELPLTPEQLETVFDSLEQNNNGYLTPVEFSMGLGKLIGINLCQGAGRTDRSSHEETFESGWSDDMDPADDEEKRFCSMMEQLGAAQVFEDPSEVRDLWARLRKERPELLANFEEFLLRVSSYIREVNHEKESMEQALKRKETDHDREVRCLYEEMEQQIRAERERLICQEALRHSRSNLLQKELRSKEQELEKILYRQKKLEHQLQSLNSEQLETRVQNERLRHLNENLLEELEKSKWELEAVKGQLQKLQKEAQNEQEQKDRDVFRVSKNMQKEKQSLLRQLELLREMNKKLRDERDTFEAKKPVSLRKKIPIPNHPPFICCCCCHHLGASHIHGGQ", "length": 491, "header": "tr|A0A8V0ZRD7-1|A0A8V0ZRD7_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=EFCAB4B PE=1 SV=1 CANONICAL=A0A8V0ZRF4-1" }, "locus": { "chromosome": "5", "start_pos": 15334493, "end_pos": 15324117, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056292.1", "url": "https://www.ensembl.org/id/ENSGALT00010056292.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034072.1", "url": "https://www.ensembl.org/id/ENSGALP00010034072.1" } ] } }, { "isoform_ac": "A0A8V0ZRE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4/entry#A0A8V0ZRE6-1", "sequence": { "sequence": "MENRRSSLLRYVHWEAEEEGDEEDDVASGASPSSQMSELEDVQVEMLEKARELFQLCDKDKKGFITKLDMQRLQSELPLTPEQLETVFDSLEQNNNGYLTPVEFSMGLGKLIGINLCQGAGRTDRSSHEETFESGWSDDMDPADDEEKRFCSMMEQLGAAQVFEDPSEVRDLWARLRKERPELLANFEEFLLRVSSYIREVNHEKESMEQALKRKETDHDREVRCLYEEMEQQIRAERERLICQEALRHSRSNLLQKELRSKEQELEKILYRQKKLEHQLQSLNSEQLETRVQNERLRHLNENLLEELEKSKWELEAVKGQLQKLQKEAQNEQEQKDRDVFRVSKNMQKEKQSLLRQLELLREMNKKLRDERDTFEAKKPTTGLCGPSCHLPNGCGNGGTQQEELQILLRQWDVAEDRRRRQNELCREEQRPREVVSESRC", "length": 441, "header": "tr|A0A8V0ZRE6-1|A0A8V0ZRE6_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=EFCAB4B PE=1 SV=1 CANONICAL=A0A8V0ZRF4-1" }, "locus": { "chromosome": "5", "start_pos": 15334182, "end_pos": 15317703, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056306.1", "url": "https://www.ensembl.org/id/ENSGALT00010056306.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034082.1", "url": "https://www.ensembl.org/id/ENSGALP00010034082.1" } ] } }, { "isoform_ac": "A0A8V0ZRF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4/entry#A0A8V0ZRF4-1", "sequence": { "sequence": "MWTKCKYACCFSGGMGWPAELSIPLHCESPEAETWQRALGQLPSWAAAELCPRRKAGVITEIRHSMTESLFPLAGTAEFAARRSNQTSLLLSETWSPDTGTSEGRSCSIFPCPGAKGIEKMENRRSSLLRYVHWEAEEEGDEEDDVASGASPSSQMSELEDVQVEMLEKARELFQLCDKDKKGFITKLDMQRLQSELPLTPEQLETVFDSLEQNNNGYLTPVEFSMGLGKLIGINLCQGAGRTDRSSHEETFESGWSDDMDPADDEEKRFCSMMEQLGAAQVFEDPSEVRDLWARLRKERPELLANFEEFLLRVSSYIREVNHEKESMEQALKRKETDHDREVRCLYEEMEQQIRAERERLICQEALRHSRSNLLQKELRSKEQELEKILYRQKKLEHQLQSLNSEQLETRVQNERLRHLNENLLEELEKSKWELEAVKGQLQKLQKEAQNEQEQKDRDVFRVSKNMQKEKQSLLRQLELLREMNKKLRDERDTFEAKKPAPQSKKPLLKKGSVLGSYLLDDKPVKRQLASADLPVTFPMDVAMEEPNRKSCKYFSGNGTWLKTGEGDRTNFAEKNRDQEKWSVRADAEKLKMALKSDADCRKSADGLDDAPLSPRRQPVGTETRLQVLEPASCCPDRIFKVVFVGNSGVGKSSFIHRFCYDRFLADLNATIGIDYQVKSLMVDNTQVALQLWDTAGQERFRSITKQYFRKADGILVMYDITAECSFTAVRNWMSSVQEGIEDGAVVFLLGNKMDTAGRETRSVPKMEGERLAKEYKAVFYECSAMTGYNIMEPMLHMARLLTAQEDRQRENALQLEDVRRKGCCT", "length": 826, "header": "tr|A0A8V0ZRF4-1|A0A8V0ZRF4_CHICK Isoform 1 of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=EFCAB4B PE=1 SV=1 CANONICAL=A0A8V0ZRF4-1" }, "locus": { "chromosome": "5", "start_pos": 15346658, "end_pos": 15310994, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056314.1", "url": "https://www.ensembl.org/id/ENSGALT00010056314.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034087.1", "url": "https://www.ensembl.org/id/ENSGALP00010034087.1" } ] } }, { "isoform_ac": "A0A8V0ZTC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4/entry#A0A8V0ZTC1-1", "sequence": { "sequence": "MENRRSSLLRYVHWEAEEEGDEEDDVASGASPSSQMSELEDVQVEMLEKARELFQLCDKDKKGFITKLDMQRLQSELPLTPEQLETVFDSLEQNNNGYLTPVEFSMGLGKLIGINLCQGAGRTDRSSHEETFESGWSDDMDPADDEEKRFCSMMEQLGAAQVFEDPSEVRDLWARLRKERPELLANFEEFLLRVSSYIREVNHEKESMEQALKRKETDHDREVRCLYEEMEQQIRAERERLICQEALRHSRSNLLQKELRSKEQELEKILYRQKKVTEPKAFLK", "length": 284, "header": "tr|A0A8V0ZTC1-1|A0A8V0ZRF4_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=EFCAB4B PE=1 SV=1 CANONICAL=A0A8V0ZRF4-1" }, "locus": { "chromosome": "5", "start_pos": 15334182, "end_pos": 15328556, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056295.1", "url": "https://www.ensembl.org/id/ENSGALT00010056295.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034074.1", "url": "https://www.ensembl.org/id/ENSGALP00010034074.1" } ] } }, { "isoform_ac": "A0A8V0ZUE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4/entry#A0A8V0ZUE5-1", "sequence": { "sequence": "MAQQLQGTAEFAARRSNQTSLLLSETWSPDTGTSEGRSCSIFPCPGAKGIEKMENRRSSLLRYVHWEAEEEGDEEDDVASGASPSSQMSELEDVQVEMLEKARELFQLCDKDKKGFITKLDMQRLQSELPLTPEQLETVFDSLEQNNNGYLTPVEFSMGLGKLIGINLCQGAGRTDRSSHEETFESGWSDDMDPADDEEKRFCSMMEQLGAAQVFEDPSEVRDLWARLRKERPELLANFEEFLLRVSSYIREVNHEKESMEQALKRKETDHDREVRCLYEEMEQQIRAERERLICQEALRHSRSNLLQKELRSKEQELEKILYRQKKLEHQLQSLNSEQLETRVQNERLRHLNENLLEELEKSKWELEAVKGQLQKLQKEAQNEQEQKDRDVFRVSKNMQKEKQSLLRQLELLREMNKKLRDERDTFEAKKPVSLRKKIPIPNHPPFICCCCCHHLGASHIHGGQ", "length": 465, "header": "tr|A0A8V0ZUE5-1|A0A8V0ZRF4_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=EFCAB4B PE=1 SV=1 CANONICAL=A0A8V0ZRF4-1" }, "locus": { "chromosome": "5", "start_pos": 15347758, "end_pos": 15324117, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056299.1", "url": "https://www.ensembl.org/id/ENSGALT00010056299.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034078.1", "url": "https://www.ensembl.org/id/ENSGALP00010034078.1" } ] } }, { "isoform_ac": "A0A8V0ZUH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4/entry#A0A8V0ZUH0-1", "sequence": { "sequence": "MENRRSSLLRYVHWEAEEEGDEEDDVASGASPSSQMSELEDVQVEMLEKARELFQLCDKDKKGFITKLDMQRLQSELPLTPEQLETVFDSLEQNNNGYLTPVEFSMGLGKLIGINLCQGAGRTDRSSHEETFESGWSDDMDPADDEEKRFCSMMEQLGAAQVFEDPSEVRDLWARLRKERPELLANFEEFLLRVSSYIREVNHEKESMEQALKRKETDHDREVRCLYEEMEQQIRAERERLICQEALRHSRSNLLQKELRSKEQELEKILYRQKKLEHQLQSLNSEQLETRVQNERLRHLNENLLEELEKSKWELEAVKGQLQKLQKEAQNEQEQKDRDVFRVSKNMQKEKQSLLRQLELLREMNKKLRDERDTFEAKKPEGIEDGAVVFLLGNKMDTAGRETRSVPKMEGERLAKEYKAVFYECSAMTGYNIMEPMLHMARLLTAQEDRQRENALQLEDVRRKGCCT", "length": 468, "header": "tr|A0A8V0ZUH0-1|A0A8V0ZRF4_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=EFCAB4B PE=1 SV=1 CANONICAL=A0A8V0ZRF4-1" }, "locus": { "chromosome": "5", "start_pos": 15334182, "end_pos": 15310994, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056328.1", "url": "https://www.ensembl.org/id/ENSGALT00010056328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034098.1", "url": "https://www.ensembl.org/id/ENSGALP00010034098.1" } ] } }, { "isoform_ac": "A0A8V0ZYV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4/entry#A0A8V0ZYV5-1", "sequence": { "sequence": "MRNLPWECNGSIPCAFSALTAASQPALERGWDALGALQTTPPAETCSDILCTVAVLFLPLLFGVEYCWLQGRGVKPSCSWSCSIFPCPGAKGIEKMENRRSSLLRYVHWEAEEEGDEEDDVASGASPSSQMSELEDVQVEMLEKARELFQLCDKDKKGFITKLDMQRLQSELPLTPEQLETVFDSLEQNNNGYLTPVEFSMGLGKLIGINLCQGAGRTDRSSHEETFESGWSDDMDPADDEEKRFCSMMEQLGAAQVFEDPSEVRDLWARLRKERPELLANFEEFLLRVSSYIREVNHEKESMEQALKRKETDHDREVRCLYEEMEQQIRAERERLICQEALRHSRSNLLQKELRSKEQELEKILYRQKKLEHQLQSLNSEQLETRVQNERLRHLNENLLEELEKSKWELEAVKGQLQKLQKEAQNEQEQKDRDVFRVSKNMQKEKQSLLRQLELLREMNKKLRDERDTFEAKKPVSLRKKIPIPNHPPFICCCCCHHLGASHIHGGQ", "length": 508, "header": "tr|A0A8V0ZYV5-1|A0A8V0ZRF4_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=EFCAB4B PE=1 SV=1 CANONICAL=A0A8V0ZRF4-1" }, "locus": { "chromosome": "5", "start_pos": 15343797, "end_pos": 15324117, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056297.1", "url": "https://www.ensembl.org/id/ENSGALT00010056297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034076.1", "url": "https://www.ensembl.org/id/ENSGALP00010034076.1" } ] } }, { "isoform_ac": "A0A8V0ZYX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4/entry#A0A8V0ZYX7-1", "sequence": { "sequence": "MENRRSSLLRYVHWEAEEEGDEEDDVASGASPSSQMSELEDVQVEMLEKARELFQLCDKDKKGFITKLDMQRLQSELPLTPEQLETVFDSLEQNNNGYLTPVEFSMGLGKLIGINLCQGAGRTDRSSHEETFESGWSDDMDPADDEEKRFCSMMEQLGAAQVFEDPSEVRDLWARLRKERPELLANFEEFLLRVSSYIREVNHEKESMEQALKRKETDHDREVRCLYEEMEQQIRAERERLICQEALRHSRSNLLQKELRSKEQELEKILYRQKKLEHQLQSLNSEQLETRVQNERLRHLNENLLEELEKSKWELEAVKGQLQKLQKEAQNEQEQKDRDVFRVSKNMQKEKQSLLRQLELLRQLASADLPVTFPMDVAMEEPNRKSCKYFSGNGTWLKTGEGDRTNFAEKNRDQEKWSVRADAEKLKMALKSDADCRKSADGLDDAPLSPRRQPVGTETRLQVLEPASCCPDRIFKVVFVGNSGVGKSSFIHRFCYDRFLADLNATIGIDYQVKSLMVDNTQVALQLWDTAGQERFRSITKQYFRKADGILVMYDITAECSFTAVRNWMSSVQEGIEDGAVVFLLGNKMDTAGRETRSVPKMEGERLAKEYKAVFYECSAMTGYNIMEPMLHMARLLTAQEDRQRENALQLEDVRRKGCCT", "length": 661, "header": "tr|A0A8V0ZYX7-1|A0A8V0ZRF4_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=EFCAB4B PE=1 SV=1 CANONICAL=A0A8V0ZRF4-1" }, "locus": { "chromosome": "5", "start_pos": 15334182, "end_pos": 15310994, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056318.1", "url": "https://www.ensembl.org/id/ENSGALT00010056318.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034091.1", "url": "https://www.ensembl.org/id/ENSGALP00010034091.1" } ] } }, { "isoform_ac": "A0A8V0ZYY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4/entry#A0A8V0ZYY1-1", "sequence": { "sequence": "MENRRSSLLRYVHWEAEEEGDEEDDVASGASPSSQMSELEDVQVEMLEKARELFQLCDKDKKGFITKLDMQRLQSELPLTPEQLETVFDSLEQNNNGYLTPVEFSMGLGKLIGINLCQGAGRTDRSSHEETFESGWSDDMDPADDEEKRFCSMMEQLGAAQVFEDPSEVRDLWARLRKERPELLANFEEFLLRVSSYIREVNHEKESMEQALKRKETDHDREVRCLYEEMEQQIRAERERLICQEALRHSRSNLLQKELRSKEQELEKILYRQKKLEHQLQSLNSEQLETRVQNERLRHLNENLLEELEKSKWELEAVKGQLQKLQKEAQNEQEQKDRDVFRVSKNMQKEKQSLLRQLELLSREMNKKLRDERDTFEAKKPAPQSKKPLLKKGSVLGSYLLDDKPVKRQKPCLLVPRARACVPGAWERAGLAQGWCSLQQLKALRRRPSSRQLASADLPVTFPMDVAMEEPNRKSCKYFSGNGTWLKTGEGDRTNFAEKNRDQEKWSVRADAEKLKMALKSDADCRKSADGLDDAPLSPRRQPVGTETRLQVLEPASCCPDRIFKVVFVGNSGVGKSSFIHRFCYDRFLADLNATIGIDYQVKSLMVDNTQVALQLWDTAGQERFRSITKQYFRKADGILVMYDITAECSFTAVRNWMSSVQEGIEDGAVVFLLGNKMDTAGRETRSVPKMEGERLAKEYKAVFYECSAMTGYNIMEPMLHMARLLTAQEDRQRENALQLEDVRRKGCCT", "length": 750, "header": "tr|A0A8V0ZYY1-1|A0A8V0ZRF4_CHICK Computationally mapped isoform of EF-hand domain-containing protein OS=Gallus gallus OX=9031 GN=EFCAB4B PE=1 SV=1 CANONICAL=A0A8V0ZRF4-1" }, "locus": { "chromosome": "5", "start_pos": 15334182, "end_pos": 15310994, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056324.1", "url": "https://www.ensembl.org/id/ENSGALT00010056324.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034096.1", "url": "https://www.ensembl.org/id/ENSGALP00010034096.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF4" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 165, "end_pos": 200, "start_aa": "Glu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 558, "end_pos": 560 }, { "start_pos": 669, "end_pos": 671 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQ96-1", "uniprot_ac": "A0A8V0ZQ96", "uniprot_id": "A0A8V0ZQ96_CHICK", "mass": { "chemical_mass": 34915.0, "monoisotopic_mass": 34915.0 }, "refseq": {}, "gene_names": [ { "name": "MRPL45", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein mL45", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L45, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the mitochondrial large ribosomal subunit (mt-LSU). Within the mitochondrial ribosomes, required to direct the nascent polypeptide toward the tunnel exit and position the exit at a distance from the membrane surface.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZZ73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ73#function" }, { "database": "UniProtKB", "id": "ARBA00045355", "url": "https://www.uniprot.org/uniprotkb/ARBA00045355#function" }, { "database": "UniProtKB", "id": "A0A8V0ZQ96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96#function" }, { "database": "UniProtKB", "id": "A0A8V0ZVI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVI0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPL45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96", "locus": { "chromosome": "27", "start_pos": 3830811, "end_pos": 3822811, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024039", "url": "https://www.ensembl.org/id/ENSGALG00010024039" } ] } } ], "crossref": [ { "id": "A0A8V0ZQ96", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQ96", "database": "AlphaFoldDB", "categories": [] }, { "id": "426233", "url": "https://www.ncbi.nlm.nih.gov/gene/426233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051975", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051975", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426233", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426233", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HTHMAAK", "url": "https://omabrowser.org/oma/group/HTHMAAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ96", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVI0", "url": "https://www.orthodb.org/?gene=A0A8V0ZVI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZ73", "url": "https://www.orthodb.org/?gene=A0A8V0ZZ73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28554", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28554", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28554:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28554:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04280", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04280", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQ96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ73", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGTEGHCTGGATKQTLHLFHGAMESLLRPPRAVPAFLVVPVRTKRRLFVPEWARELPHEEKEKRLQSLIRTLPEERMERTFYLACTASIIDPYVPPEGDARVTSLSKEGLKQRMEKLKQTAASQLALRKVKDHDPNFSTKTFPEVAQEIYVEAHNSLANFNKQKLHSLVTERCYPDMVRGNRYKTIRWSFVESLEPPRVVHVRCTSVVNQGNLYGQVTVRMHTRQTLAIYDRFGRLMYGGEKLPKDVLEYVVFERYLVNPYGTWRMHGKIVPEWAPPKDPIVKTVMIPGPTLDPSQEYEEMK", "length": 303, "header": "tr|A0A8V0ZQ96-1|A0A8V0ZQ96_CHICK Isoform 1 of Large ribosomal subunit protein mL45 OS=Gallus gallus OX=9031 GN=MRPL45 PE=3 SV=1 CANONICAL=A0A8V0ZQ96-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQ96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96/entry#A0A8V0ZQ96-1", "sequence": { "sequence": "MGGTEGHCTGGATKQTLHLFHGAMESLLRPPRAVPAFLVVPVRTKRRLFVPEWARELPHEEKEKRLQSLIRTLPEERMERTFYLACTASIIDPYVPPEGDARVTSLSKEGLKQRMEKLKQTAASQLALRKVKDHDPNFSTKTFPEVAQEIYVEAHNSLANFNKQKLHSLVTERCYPDMVRGNRYKTIRWSFVESLEPPRVVHVRCTSVVNQGNLYGQVTVRMHTRQTLAIYDRFGRLMYGGEKLPKDVLEYVVFERYLVNPYGTWRMHGKIVPEWAPPKDPIVKTVMIPGPTLDPSQEYEEMK", "length": 303, "header": "tr|A0A8V0ZQ96-1|A0A8V0ZQ96_CHICK Isoform 1 of Large ribosomal subunit protein mL45 OS=Gallus gallus OX=9031 GN=MRPL45 PE=3 SV=1 CANONICAL=A0A8V0ZQ96-1" }, "locus": { "chromosome": "27", "start_pos": 3829729, "end_pos": 3826251, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058563.1", "url": "https://www.ensembl.org/id/ENSGALT00010058563.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035597.1", "url": "https://www.ensembl.org/id/ENSGALP00010035597.1" } ] } }, { "isoform_ac": "A0A8V0ZVI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96/entry#A0A8V0ZVI0-1", "sequence": { "sequence": "MGISAAPRQHAVAMESLLRPPRAVPAFLVVPVRTKRRLFVPEWARELPHEEKEKRLQSLIRTLPEERMERTFYLACTASIIDPYVPPEGDARVTSLSKEGLKQRMEKLKQTAASQLALRKVKDHDPNFSTKTFPEVAQEIYVEAHNSLANFNKQKLHSLVTERCYPDMVRGNRYKTIRWSFVESLEPPRVVHVRCTSVVNQGNLYGQVTVRMHTRQTLAIYDRFGRLMYGGEKLPKDVLEYVVFERYLVNPYGTWRMHGKIVPEWAPPKDPIVKTVMIPGPTLDPSQEYEEMK", "length": 293, "header": "tr|A0A8V0ZVI0-1|A0A8V0ZQ96_CHICK Computationally mapped isoform of Large ribosomal subunit protein mL45 OS=Gallus gallus OX=9031 GN=MRPL45 PE=3 SV=1 CANONICAL=A0A8V0ZQ96-1" }, "locus": { "chromosome": "27", "start_pos": 3829729, "end_pos": 3822921, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058573.1", "url": "https://www.ensembl.org/id/ENSGALT00010058573.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035604.1", "url": "https://www.ensembl.org/id/ENSGALP00010035604.1" } ] } }, { "isoform_ac": "A0A8V0ZZ73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96/entry#A0A8V0ZZ73-1", "sequence": { "sequence": "MAAAMAAGLSRLGRGAMESLLRPPRAVPAFLVVPVRTKRRLFVPEWARELPHEEKEKRLQSLIRTLPEERMERTFYLACTASIIDPYVPPEGDARVTSLSKEGLKQRMEKLKQTAASQLALRKVKDHDPNFSTKTFPEVAQEIYVEAHNSLANFNKQKLHSLVTERCYPDMVRGNRYKTIRWSFVESLEPPRVVHVRCTSVVNQGNLYGQVTVRMHTRQTLAIYDRFGRLMYGGEKLPKDVLEYVVFERYLVNPYGTWRMHGKIVPEWAPPKDPIVKTVMIPGPTLDPSQEYEEMK", "length": 296, "header": "tr|A0A8V0ZZ73-1|A0A8V0ZQ96_CHICK Computationally mapped isoform of Large ribosomal subunit protein mL45 OS=Gallus gallus OX=9031 GN=MRPL45 PE=3 SV=1 CANONICAL=A0A8V0ZQ96-1" }, "locus": { "chromosome": "27", "start_pos": 3829729, "end_pos": 3826610, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058569.1", "url": "https://www.ensembl.org/id/ENSGALT00010058569.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035600.1", "url": "https://www.ensembl.org/id/ENSGALP00010035600.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426233", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426233", "resource": "KEGG Pathway" }, { "id": "R-GGA-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-GGA-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-GGA-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2L6W2-1", "protein_name": "Large ribosomal subunit protein mL45", "gene_name": "Mrpl45", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAPIPRGLSCLARALGWWSRQPILVTQFPAVVPVKNKSRFRPLPREPKYKTEKEFLEHARKAGLVIPPEKLERPIHLACTAGIFDPYVPPEGDARMSSLSKEGLTQRTDRFKKNVASQLAVRKIKEFDPNFKTKDFAEEAKDIFIEAHLCLNNSDHDRLHTLVTEHCFPDMVWDLKYKTVRWSFVESLEPAQVVHVRSSGLVNQSNLYGQVTVRLHTRQTLAIYDRFGRLMYGQEDVPKDVLEYVVFERHLVNPYGSWRMHAKIVPPWAPPKQPILKTLMIPGPQLNPWEEYEEIKGEAHKPQLA", "length": 306 }, "evidence": [ { "id": "A0A8V0ZQ96", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ96/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A104-1", "protein_name": "Large ribosomal subunit protein mL45", "gene_name": "Mrpl45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPIPRGLSSLSRTLGWWSRQPILVTRSTAVVPVKSKSRFRPPTREPNYKTEKEFLEYARKAGLVIPQERLERPIHLACTAGIFDPYVPPEGDARMSSLSKEGLTQRTERLRKNVASQLAIRKIKEFDANFKTKDFPEKAKDIFIEAHLCLNNSDHDRLHTLVTEHCFPDMVWELKYKTVRWSFVESLEPAQVVHVRSSGLVNQSNMYGQVTVRLHTRQTLAIYDRFGRLMYGQEDVPKDVLEYVVFERHLMNPYGSWRMHAKIVPPWAPPKQPILKTLMIPGPQLKPWEEYEETQGEAHKPQLT", "length": 306 }, "evidence": [ { "id": "A0A8V0ZQ96", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ96/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QEK4-1", "protein_name": "Large ribosomal subunit protein mL45", "gene_name": "mrpl45", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAASICRTLKCLQPTSCQNIKYGSSLLDVRLWQAVLRVPVRTKRRLFIPPSANIKSKTQDEQEKKARAAGVVVRQEYMERPINISCTAGIYDPYVPPEGDARLSTLTKEGLKQRTEQLRQTAASQLAIRKIKDYDSTFTSKEFPGIGQQIFIDAHAALTEFNKEKLHSLVTERCYPEMVRGNRYKTLRWRFIESLEPPRLVQARCPDMISKGNLYGQVTVRMHSRQTLAIYDRFGRLMLGDEEEPRDVLEYLVMERHLVNPYGRWRLHGKIVPAWAPPKDPIIKTVMIPGPKLKSGEQFEDLNYQIPKPNAVQWHK", "length": 316 }, "evidence": [ { "id": "A0A8V0ZQ96", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ96/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D0Q7-1", "protein_name": "Large ribosomal subunit protein mL45", "gene_name": "Mrpl45", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPVPRGLSSLYRTLGWWSRQPILVTQSTTVVQVKTKSRFRPPTPEPKYKTEKEFLEYARKAGLVIPQERLERPIHLACTAGIFDPYVPPEGDARMSSLSKEGLTQRTERLRKNAASQLAIRKIREFDANFKTKDFPEKAKDIFIEAHLCLNNSDHDRLHTLVTEHCFPDMVWDLKYKTVRWGFVESLEPAQVVHVRCSGLVNQSNMYGQVTVRLHTRQTLAIYDRFGRLMYGQEDVPKDVLEYVVFERHLMNPYGSWRMHAKIVPAWAPPKQPILKTLMIPGPQLKPWEEYEETQGEAQKPQLA", "length": 306 }, "evidence": [ { "id": "A0A8V0ZQ96", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ96/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCX3-1", "protein_name": "Large ribosomal subunit protein mL45", "gene_name": "mRpL45", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKLASAKTCLKLLQVMPGVQQAALLPGGGLGVLASPLQNLIQMQQVRHRQTKHWKPEFKRLRKLKFVKMDLPNLREKQEDITKEEMRSRMKERGVLPPRPWMERPFHISCTGGIFEAYVPPEGDGKKSIISTSGAKQKLEFLEKKSKSLMAVRKIRSYDENFSSDDFGAEAQDIYIQAHTHMAAKDKYKIREFVSERCYPEMMHNVKDKTIRWKFLQSLEPPRVVHARVTEVITKENQFAQVTVRFHSQQMLAIYDRFGRLMHGSEIITKDVLEYVVFEKHISNEYGKWRLHDKIIPDWLPAKQPAPITYRLIEDAEEPPKELSAGDAEVKQVDSVGEQSKEQLPLATPVESHTKPSLAI", "length": 361 }, "evidence": [ { "id": "A0A8V0ZQ96", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ96/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQ96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ96" }, { "id": "SM00978", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00978" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tim44-like", "eco_id": "ECO_0000259", "start_pos": 124, "end_pos": 272, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPB2-1", "uniprot_ac": "A0A8V0ZPB2", "uniprot_id": "A0A8V0ZPB2_CHICK", "mass": { "chemical_mass": 83389.0, "monoisotopic_mass": 83389.0 }, "refseq": {}, "gene_names": [ { "name": "SEMA7A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ] } ], "protein_names": [ { "name": "Semaphorin 7A", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SEMA7A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2", "locus": { "chromosome": "10", "start_pos": 2582142, "end_pos": 2552244, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021187", "url": "https://www.ensembl.org/id/ENSGALG00010021187" } ] } } ], "crossref": [ { "id": "A0A8V0ZPB2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPB2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000001412", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000001412", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11243", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11243", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415298", "url": "https://www.ncbi.nlm.nih.gov/gene/415298", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415298", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415298", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZB86", "url": "https://www.orthodb.org/?gene=A0A8V0ZB86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB91", "url": "https://www.orthodb.org/?gene=A0A8V0ZB91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPB2", "url": "https://www.orthodb.org/?gene=A0A8V0ZPB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NIZ9", "url": "https://www.orthodb.org/?gene=F1NIZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11036:SF80", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11036:SF80", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZB86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB91", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIZ9", "url": "https://www.uniprot.org/uniprotkb/F1NIZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NIZ9-1", "url": "https://www.uniprot.org/uniprotkb/F1NIZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELALCWLGVLSNVTEGQAGRGGCHELWDFLGSNEILVSFLRQNFQQGRKVTVMLGLLVRNQDAPLQCCCSSSWGFSADFEERSCLSRPCPAQGVCCSLAASSRWQSSAVSCSRCAWHSAASDVLLRSLCPPRCARVVVQAGERVYTFPRNEKYPVFYHETNSSSIYVGGEGMLYYYNFATSETYSVEFPVENGAQCLKPGSPEDNKNFITLIAKHGNKMLVCGTGACNPTCWHLAEKEKESPQDGRGLAPFTPDTNSLVIVDYPNIYSTIKKSQQNGKIPRFRRVKGDGELYTSDTVMQNPQFVKATTLRHEEPYQDKIYYFFREDNPDKSPEAPRNISRVAQLCKEDKGGTSSLSASKWTTFLKASLICVDPATKGNFNWLQDVFFVPASNWRDSKVYGLFTNTWGSSAVCVYSFGDIDNVFRTSKLKGYNGPNPEIKPGQCVPSGQHTPSETFKIADSHPEVEDRVEPLAPTRSPLFHNKHRYQKIGVHEVSASDGRQYTVLYLATDKGSIHKVVELPGGVHNIMELQVFSKKDPIQSMILDHERAMLYVGSTSKVVEIPMDMCGVYRNNCESCLLARDPYCGWAAGSCQSIYHNREVRQNLNLELWQGKCQKGEVKEAHSYQNVTVVPVVPFSRYYLNCPVESHYATYNWYHNDTLIKTCNNTHPQPDCFYFIQNVSHTHYGHYICVSEEDGFRQALVKEHLVNQLRFMSQKGQATMTLASWLQLLLMVVLVELFH", "length": 740, "header": "tr|A0A8V0ZPB2-1|A0A8V0ZPB2_CHICK Isoform 1 of Semaphorin 7A OS=Gallus gallus OX=9031 GN=SEMA7A PE=1 SV=1 CANONICAL=A0A8V0ZPB2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2/entry#A0A8V0ZB86-1", "sequence": { "sequence": "MSSLSLQVTGGTPKSTDSSQTPGTWVENSQNGHGQQRGSSAVCVYSFGDIDNVFRTSKLKGYNGPNPEIKPGQCVPSGQHTPSETFKIADSHPEVEDRVEPLAPTRSPLFHNKHRYQKIGVHEVSASDGRQYTVLYLATDKGSIHKVVELPGGVHNIMELQVFSKKDPIQSMILDHERAMLYVGSTSKVVEIPMDMCGVYRNNCESCLLARDPYCGWAAGSCQSIYHNREVRQNLNLELWQGKCQKGEVKEAHSYQNVTVVPVVPFSRYYLNCPVESHYATYNWYHNDTLIKTCNNTHPQPDCFYFIQNVSHTHYGHYICVSEEDGFRQALVKEHLVNQLRFMSQKGQATMTLASWLQLLLMVVLVELFH", "length": 370, "header": "tr|A0A8V0ZB86-1|A0A8V0ZPB2_CHICK Computationally mapped isoform of Semaphorin 7A OS=Gallus gallus OX=9031 GN=SEMA7A PE=1 SV=1 CANONICAL=A0A8V0ZPB2-1" }, "locus": { "chromosome": "10", "start_pos": 2580670, "end_pos": 2575664, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051341.1", "url": "https://www.ensembl.org/id/ENSGALT00010051341.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030532.1", "url": "https://www.ensembl.org/id/ENSGALP00010030532.1" } ] } }, { "isoform_ac": "A0A8V0ZB91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2/entry#A0A8V0ZB91-1", "sequence": { "sequence": "MLGAAALGRRGPPLRRGGKRELEREHPIALRGGERVYTFPRNEKYPVFYHETNSSSIYVGGEGMLYYYNFATSETYSVEFPVENGAQCLKPGSPEDNKNFITLIAKHGNKMLVCGTGACNPTCWHLAEKEKESPQDGRGLAPFTPDTNSLVIVDYPNIYSTIKKSQQNGKIPRFRRVKGDGELYTSDTVMQNPQFVKATTLRHEEPYQDKIYYFFREDNPDKSPEAPRNISRVAQLCKEDKGGTSSLSASKWTTFLKASLICVDPATKGNFNWLQDVFFVPASNWRDSKVYGLFTNTWGSSAVCVYSFGDIDNVFRTSKLKGYNGPNPEIKPGQCVPSGQHTPSETFKIADSHPEVEDRVEPLAPTRSPLFHNKHRYQKIGVHEVSASDGRQYTVLYLATDKGSIHKVVELPGGVHNIMELQVFSKKDPIQSMILDHERAMLYVGSTSKVVEIPMDMCGVYRNNCESCLLARDPYCGWAAGSCQSIYHNREVRQNLNLELWQGKCQKGEVKEAHSYQNVTVVPVVPFSRYYLNCPVESHYATYNWYHNDTLIKTCNNTHPQPDCFYFIQNVSHTHYGHYICVSEEDGFRQALVKEHLVNQLRFMSQKGQATMTLASWLQLLLMVVLVELFH", "length": 631, "header": "tr|A0A8V0ZB91-1|A0A8V0ZPB2_CHICK Computationally mapped isoform of Semaphorin 7A OS=Gallus gallus OX=9031 GN=SEMA7A PE=1 SV=1 CANONICAL=A0A8V0ZPB2-1" }, "locus": { "chromosome": "10", "start_pos": 2580670, "end_pos": 2570942, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051346.1", "url": "https://www.ensembl.org/id/ENSGALT00010051346.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030537.1", "url": "https://www.ensembl.org/id/ENSGALP00010030537.1" } ] } }, { "isoform_ac": "A0A8V0ZPB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2/entry#A0A8V0ZPB2-1", "sequence": { "sequence": "MELALCWLGVLSNVTEGQAGRGGCHELWDFLGSNEILVSFLRQNFQQGRKVTVMLGLLVRNQDAPLQCCCSSSWGFSADFEERSCLSRPCPAQGVCCSLAASSRWQSSAVSCSRCAWHSAASDVLLRSLCPPRCARVVVQAGERVYTFPRNEKYPVFYHETNSSSIYVGGEGMLYYYNFATSETYSVEFPVENGAQCLKPGSPEDNKNFITLIAKHGNKMLVCGTGACNPTCWHLAEKEKESPQDGRGLAPFTPDTNSLVIVDYPNIYSTIKKSQQNGKIPRFRRVKGDGELYTSDTVMQNPQFVKATTLRHEEPYQDKIYYFFREDNPDKSPEAPRNISRVAQLCKEDKGGTSSLSASKWTTFLKASLICVDPATKGNFNWLQDVFFVPASNWRDSKVYGLFTNTWGSSAVCVYSFGDIDNVFRTSKLKGYNGPNPEIKPGQCVPSGQHTPSETFKIADSHPEVEDRVEPLAPTRSPLFHNKHRYQKIGVHEVSASDGRQYTVLYLATDKGSIHKVVELPGGVHNIMELQVFSKKDPIQSMILDHERAMLYVGSTSKVVEIPMDMCGVYRNNCESCLLARDPYCGWAAGSCQSIYHNREVRQNLNLELWQGKCQKGEVKEAHSYQNVTVVPVVPFSRYYLNCPVESHYATYNWYHNDTLIKTCNNTHPQPDCFYFIQNVSHTHYGHYICVSEEDGFRQALVKEHLVNQLRFMSQKGQATMTLASWLQLLLMVVLVELFH", "length": 740, "header": "tr|A0A8V0ZPB2-1|A0A8V0ZPB2_CHICK Isoform 1 of Semaphorin 7A OS=Gallus gallus OX=9031 GN=SEMA7A PE=1 SV=1 CANONICAL=A0A8V0ZPB2-1" }, "locus": { "chromosome": "10", "start_pos": 2580670, "end_pos": 2552443, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051352.1", "url": "https://www.ensembl.org/id/ENSGALT00010051352.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030543.1", "url": "https://www.ensembl.org/id/ENSGALP00010030543.1" } ] } }, { "isoform_ac": "F1NIZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2/entry#F1NIZ9-1", "sequence": { "sequence": "MGSRSLLTLLVALSACQLGVRAAGRSKVNPRVVVTPRGERVYTFPRNEKYPVFYHETNSSSIYVGGEGMLYYYNFATSETYSVEFPVENGAQCLKPGSPEDNKNFITLIAKHGNKMLVCGTGACNPTCWHLAEKEKESPQDGRGLAPFTPDTNSLVIVDYPNIYSTIKKSQQNGKIPRFRRVKGDGELYTSDTVMQNPQFVKATTLRHEEPYQDKIYYFFREDNPDKSPEAPRNISRVAQLCKEDKGGTSSLSASKWTTFLKASLICVDPATKGNFNWLQDVFFVPASNWRDSKVYGLFTNTWGSSAVCVYSFGDIDNVFRTSKLKGYNGPNPEIKPGQCVPSGQHTPSETFKIADSHPEVEDRVEPLAPTRSPLFHNKHRYQKIGVHEVSASDGRQYTVLYLATDKGSIHKVVELPGGVHNIMELQVFSKKDPIQSMILDHERAMLYVGSTSKVVEIPMDMCGVYRNNCESCLLARDPYCGWAAGSCQSIYHNREVRQNLNLELWQGKCQKGEVKEAHSYQNVTVVPVVPFSRYYLNCPVESHYATYNWYHNDTLIKTCNNTHPQPDCFYFIQNVSHTHYGHYICVSEEDGFRQALVKEHLVNQLRFMSQKGQATMTLASWLQLLLMVVLVELFH", "length": 636, "header": "tr|F1NIZ9-1|A0A8V0ZPB2_CHICK Computationally mapped isoform of Semaphorin 7A OS=Gallus gallus OX=9031 GN=SEMA7A PE=1 SV=2 CANONICAL=A0A8V0ZPB2-1" }, "locus": { "chromosome": "10", "start_pos": 2580670, "end_pos": 2559527, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051349.1", "url": "https://www.ensembl.org/id/ENSGALT00010051349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030540.1", "url": "https://www.ensembl.org/id/ENSGALP00010030540.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415298", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415298", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "GABA-ergic synapse", "id": "GO:0098982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "semaphorin receptor binding", "id": "GO:0030215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030215", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "chemorepellent activity", "id": "GO:0045499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045499", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "semaphorin-plexin signaling pathway", "id": "GO:0071526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071526", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "regulation of inflammatory response", "id": "GO:0050727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "positive regulation of axon extension", "id": "GO:0045773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045773", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "negative chemotaxis", "id": "GO:0050919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050919", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB2" } ], "pmid": "" }, { "name": "positive regulation of 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CANONICAL=A0A8V0ZP69-1" }, "locus": { "chromosome": "5", "start_pos": 724547, "end_pos": 720696, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054089.1", "url": "https://www.ensembl.org/id/ENSGALT00010054089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032620.1", "url": "https://www.ensembl.org/id/ENSGALP00010032620.1" } ] } }, { "isoform_ac": "A0A8V0ZP69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP69/entry#A0A8V0ZP69-1", "sequence": { "sequence": "GRRVSGGVTGPACEGKRALGLWWRGLRLVSVGASGRGCSSSGPLSRCSHGLLPTYCRQFWAECFCGAFGQAFSYPDGFLAPDLALLCIMAILEALRLYLGSKGNLTEEEAPLGLSLVITVGSMILSVYFLIWQTYVLRADVIINTVLLFTYGLESVFQVLAIAAFVG", "length": 167, "header": "tr|A0A8V0ZP69-1|A0A8V0ZP69_CHICK Isoform 1 of Transmembrane protein 80 OS=Gallus gallus OX=9031 GN=TMEM80 PE=4 SV=1 CANONICAL=A0A8V0ZP69-1" }, "locus": { "chromosome": "5", "start_pos": 724692, "end_pos": 720696, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": 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"database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9D3H0-1", "protein_name": "Transmembrane protein 80", "gene_name": "Tmem80", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFHLSGLYSALYFLATLLMIVYKSQVFSYPCNCLALDLVLLLLMGILKVAQLYLGTKGNLMEAEVPLAASLAFTAVGGLLSVHFLLWQTLVLWMDSVLSTVLLVLHGLEAGLQVVVIADFIR", "length": 123 }, "evidence": [ { "id": "A0A8V0ZP69", "url": "https://omabrowser.org/oma/group/A0A8V0ZP69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP69" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP69" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "non-motile cilium assembly", "id": "GO:1905515", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905515", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPP6-1", "uniprot_ac": "A0A8V0ZPP6", "uniprot_id": "A0A8V0ZPP6_CHICK", "mass": { "chemical_mass": 67500.0, "monoisotopic_mass": 67500.0 }, "refseq": {}, "gene_names": [ { "name": "MIGA1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6" } ] } ], "protein_names": [ { "name": "Mitoguardin 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MIGA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6", "locus": { "chromosome": "8", "start_pos": 18632201, "end_pos": 18669650, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022325", "url": "https://www.ensembl.org/id/ENSGALG00010022325" } ] } } ], "crossref": [ { "id": "A0A8V0ZPP6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "771457", "url": "https://www.ncbi.nlm.nih.gov/gene/771457", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WENTEAE", "url": "https://omabrowser.org/oma/group/WENTEAE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPP6", "url": "https://www.orthodb.org/?gene=A0A8V0ZPP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ58", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ68", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVC0", "url": "https://www.orthodb.org/?gene=A0A8V0ZVC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVC5", "url": "https://www.orthodb.org/?gene=A0A8V0ZVC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21508", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21508", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21508:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21508:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10265", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10265", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483166", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483166", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZPP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVC5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEEAVTEARFSLKTVALRAFHLPVSWYHSLTQIKLSPGLKKLFTVTAVSAISVIFLAHHFKRKRGRKNKQVSPWEPGHLLLECTKAAASEKGSSCSSSRQNLTLSLSSAKEKGSQSCIYANGGLFSKYSGSVQSLVSSATSCHSCACANSNSWDKADEEDIKLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRNRQVEDEASCSSIKLGAGDAIAEESVEDIISAEFIHKLESLLQRAYRLQEEFEATLGTSDPASLANDIDKNTDITVKDNTDDFCLRDTLSIASTDSFVSTAELTEHREARNTYGLDSLCHCPLYEEAMHLAEEGKIYSRVLRTEMFECLGDSDFLAKLHCIRQAFQIILSETANRIFLAESGRKILSALIVRARKNPKKFEDVFDEMIYFLEQTDHWDNTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPISIQNVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKVPDGFFAHFYAICEHISPVLAWGFLGPRNSLYDLCCFFKDQVLFFLKDIFDFEKVRYSTMESLAEDLMQLLIRRTELLMAYLGADSLRHASACVSGHGHVMTSGLLEAKVQ", "length": 599, "header": "tr|A0A8V0ZPP6-1|A0A8V0ZPP6_CHICK Isoform 1 of Mitoguardin 1 OS=Gallus gallus OX=9031 GN=MIGA1 PE=3 SV=1 CANONICAL=A0A8V0ZPP6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6/entry#A0A8V0ZPP6-1", "sequence": { "sequence": "MSEEAVTEARFSLKTVALRAFHLPVSWYHSLTQIKLSPGLKKLFTVTAVSAISVIFLAHHFKRKRGRKNKQVSPWEPGHLLLECTKAAASEKGSSCSSSRQNLTLSLSSAKEKGSQSCIYANGGLFSKYSGSVQSLVSSATSCHSCACANSNSWDKADEEDIKLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRNRQVEDEASCSSIKLGAGDAIAEESVEDIISAEFIHKLESLLQRAYRLQEEFEATLGTSDPASLANDIDKNTDITVKDNTDDFCLRDTLSIASTDSFVSTAELTEHREARNTYGLDSLCHCPLYEEAMHLAEEGKIYSRVLRTEMFECLGDSDFLAKLHCIRQAFQIILSETANRIFLAESGRKILSALIVRARKNPKKFEDVFDEMIYFLEQTDHWDNTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPISIQNVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKVPDGFFAHFYAICEHISPVLAWGFLGPRNSLYDLCCFFKDQVLFFLKDIFDFEKVRYSTMESLAEDLMQLLIRRTELLMAYLGADSLRHASACVSGHGHVMTSGLLEAKVQ", "length": 599, "header": "tr|A0A8V0ZPP6-1|A0A8V0ZPP6_CHICK Isoform 1 of Mitoguardin 1 OS=Gallus gallus OX=9031 GN=MIGA1 PE=3 SV=1 CANONICAL=A0A8V0ZPP6-1" }, "locus": { "chromosome": "8", "start_pos": 18668148, "end_pos": 18634502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054313.1", "url": "https://www.ensembl.org/id/ENSGALT00010054313.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032804.1", "url": "https://www.ensembl.org/id/ENSGALP00010032804.1" } ] } }, { "isoform_ac": "A0A8V0ZQ58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6/entry#A0A8V0ZQ58-1", "sequence": { "sequence": "MSEEAVTEARFSLKTVALRAFHLPVSWYHSLTQIKLSPGLKKLFTVTAVSAISVIFLAHHFKRKRGRKNKQVSPWEPGHLLLECTKAAASEKGSSCSSSRQNLTLSLSSAKEKGSQSCIYANGGLFSKYSGSVQSLVSVQSATSCHSCACANSNSWDKADEEDIKLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRNRQVEDEASCSSIKLGAGDAIAEESVEDIISAEFIHKLESLLQRAYRLQEEFEATLGTSDPASLANDIDKNTDITVKDNTDDFCLRDTLSIASTDSFVSTAELTEHREARNTYGLDSLCHCPLYEEAMHLAEEGKIYSRVLRTEMFECLGDSDFLAKLHCIRQAFQIILSETANRIFLAESGRKILSALIVRARKNPKKFEDVFDEMIYFLEQTDHWDNTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPISIQNVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKDQVLFFLKDIFDFEKVRYSTMESLAEDLMQLLIRRTELLMAYLGADSLRHASACVSGHGHVMTSGLLEAKVQ", "length": 562, "header": "tr|A0A8V0ZQ58-1|A0A8V0ZQ58_CHICK Computationally mapped isoform of Mitoguardin 1 OS=Gallus gallus OX=9031 GN=MIGA1 PE=3 SV=1 CANONICAL=A0A8V0ZPP6-1" }, "locus": { "chromosome": "8", "start_pos": 18668148, "end_pos": 18634502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054307.1", "url": "https://www.ensembl.org/id/ENSGALT00010054307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032798.1", "url": "https://www.ensembl.org/id/ENSGALP00010032798.1" } ] } }, { "isoform_ac": "A0A8V0ZQ68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6/entry#A0A8V0ZQ68-1", "sequence": { "sequence": "MSEEAVTEARFSLKTVALRAFHLPVSWYHSLTQIKLSPGLKKLFTVTAVSAISVIFLAHHFKRKRGRKNKQVSPWEPGHLLLECTKAAASEKGSSCSSSRQNLTLSLSSAKEKGSQSCIYANGGLFSKYSGSVQSLVSVQSATSCHSCACANSNSWDKADEEDIKLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRNRQVEDEASCSSIKLGAGDAIAEESVEDIISAEFIHKLESLLQRAYRLQEEFEATLGTSDPASLANDIEHREARNTYGLDSLCHCPLYEEAMHLAEEGKIYSRVLRTEMFECLGDSDFLAKLHCIRQAFQIILSETANRIFLAESGRKILSALIVRARKNPKKFEDVFDEMIYFLEQTDHWDNTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPISIQNVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKVPDGFFAHFYAICEHISPVLAWGFLGPRNSLYDLCCFFKDQVLFFLKDIFDFEKVRYSTMESLAEDLMQLLIRRTELLMAYLGADSLRHASACVSGHGHVMTSGLLEAKVQ", "length": 565, "header": "tr|A0A8V0ZQ68-1|A0A8V0ZQ68_CHICK Computationally mapped isoform of Mitoguardin 1 OS=Gallus gallus OX=9031 GN=MIGA1 PE=3 SV=1 CANONICAL=A0A8V0ZPP6-1" }, "locus": { "chromosome": "8", "start_pos": 18668148, "end_pos": 18634502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054319.1", "url": "https://www.ensembl.org/id/ENSGALT00010054319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032808.1", "url": "https://www.ensembl.org/id/ENSGALP00010032808.1" } ] } }, { "isoform_ac": "A0A8V0ZVC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6/entry#A0A8V0ZVC0-1", "sequence": { "sequence": "MSEEAVTEARFSLKTVALRAFHLPVSWYHSLTQIKLSPGLKKLFTVTAVSAISVIFLAHHFKRKRGRKNKQVSPWEPGHLLLECTKAAASEKGSSCSSSRQNLTLSLSSAKEKGSQSCIYANGGLFSKYSGSVQSLVSVQSATSCHSCACANSNSWDKADEEDIKLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRNRQVEDEASCSSIKLGAGDAIAEESVEDIISAEFIHKLESLLQRAYRLQEEFEATLGTSDPASLANDIDKNTDITVKDNTDDFCLRDTLSIASTDSFVSTAELTEHREARNTYGLDSLCHCPLYEEAMHLAEEGKIYSRVLRTEMFECLGDSDFLAKLHCIRQAFQIILSETANRIFLAESGRKILSALIVRARKNPKKFEDVFDEMIYFLEQTDHWDNTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPISIQNVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKVPDGFFAHFYAICEHISPVLAWGFLGPRNSLYDLCCFFKDQVLFFLKDIFDFEKVRYSTMESLAEDLMQLLIRRTELLMAYLGADSLRHASACVSGHGHVMTSGLLEAKLSLLLMSKHLKMYHVAK", "length": 616, "header": "tr|A0A8V0ZVC0-1|A0A8V0ZPP6_CHICK Computationally mapped isoform of Mitoguardin 1 OS=Gallus gallus OX=9031 GN=MIGA1 PE=3 SV=1 CANONICAL=A0A8V0ZPP6-1" }, "locus": { "chromosome": "8", "start_pos": 18668148, "end_pos": 18634374, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054310.1", "url": "https://www.ensembl.org/id/ENSGALT00010054310.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032801.1", "url": "https://www.ensembl.org/id/ENSGALP00010032801.1" } ] } }, { "isoform_ac": "A0A8V0ZVC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6/entry#A0A8V0ZVC5-1", "sequence": { "sequence": "MSEEAVTEARFSLKTVALRAFHLPVSWYHSLTQIKLSPGLKKLFTVTAVSAISVIFLAHHFKRKRGRKNKQVSPWEPGHLLLECTKAAASEKGSSCSSSRQNLTLSLSSAKEKGSQSCIYANGGLFSKYSGSVQSLVSVQSATSCHSCACANSNSWDKADEEDIKLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRNRQVEDEASCSSIKLGAGDAIAEESVEDIISAEFIHKLESLLQRAYRLQEEFEATLGTSDPASLANDIDKNTDITVKDNTDDFCLRDTLSIASTDSFVSTAELTEHREARNTYGLDSLCHCPLYEEAMHLAEEGKIYSRVLRTEMFECLGDSDFLAKLHCIRQAFQIILSETANRIFLAESGRKILSALIVRARKNPKKFEDVFDEMIYFLEQTDHWDNTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPISIQNVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKVPDGFFAHFYAICEHISPVLAWGFLGPRNSLYDLCCFFKDQVLFFLKDIFDFEKVRYSTMESLAEDLMQLLIRRTELLMAYLGADSLRHASACVSGHGHVMTSGLLEAKVQ", "length": 601, "header": "tr|A0A8V0ZVC5-1|A0A8V0ZPP6_CHICK Computationally mapped isoform of Mitoguardin 1 OS=Gallus gallus OX=9031 GN=MIGA1 PE=3 SV=1 CANONICAL=A0A8V0ZPP6-1" }, "locus": { "chromosome": "8", "start_pos": 18668148, "end_pos": 18634502, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054316.1", "url": "https://www.ensembl.org/id/ENSGALT00010054316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032806.1", "url": "https://www.ensembl.org/id/ENSGALP00010032806.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1483166", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483166", "resource": "Reactome", "description": "Synthesis of PA" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K2T2-1", "protein_name": "Mitoguardin 1", "gene_name": "Miga1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGETVSRSQFSLKTCAIRVFALPVSWYYSLSQIKFPPAAKKLFMVTAVSAVSVIFLAHHFKRRRGKQKGKVLPWEPEHLLLEHTRRAASDKGSSCSSSRQNLTLSLSSTKDKGSQSCNYPNGGLLSRYSGSAQSLGSVQSVNSCHSCACGNSNSWDKADDDDVRLVNIPVTTPENLYLMGMELFEEALHRWEQALTFRSRQAEDEACSSVKLGAGDAIAEESVDDIISTEFIHKLEALLQRAYRLQEEFEAALGGSDPDSLANDTDKDTDLSVRETVDEFGLPDTANIDSADLFASATELAEHREAQQALSLESFCRCPFYEEAMHLVEEGKIHSRVLRTEMLECLGDSDFLAKLHCIRQAFQLILAEADNRSFLAESGRKILSALIVKARKNPKKFQDVFDEMIYFLEQTDHWDSTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPTSIQSVVTNHWLSASFKETAVASSCWSVLKQKRQQMKQISDGFFAHFYAICEHISPVLAWGFLGPRNSLYDLCCFFKNQVLFFLKDIFDFEKVRYSSIDTLAEDLTHLLIRRTELLVTCLGADALRQATTCTSGHSHAVPTALLEARVQ", "length": 601 }, "evidence": [ { "id": "A0A8V0ZPP6", "url": "https://omabrowser.org/oma/group/A0A8V0ZPP6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A9J7HBY1-1", "protein_name": "Mitoguardin 1 isoform X2", "gene_name": "Miga1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGGTVRESQFSLKMAALRVFDLPVSWYYALSQIKFSPVAKKLFVVTAVSAISVIFFAHHFKRRRGKKKGKILPWEPENLILEHTRRAASDKGSSCSSSRQNLTLSLSSTKDKAWQSYNYTNGGLFSKYSGSAQSLASVQSVNSCHSCACGNSNSWDKADEDDIKLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRSRQAEEEACSSVKLGAGDAIAEESVDDIISTEFIHKLEALLQRAYRLQEEFEATLGGSDPNSLANDTDKDTDVSMKETMDDFGLQDTLNSESDLFASAAELPEHREARHTYSLESFCRCPFYEEAMHLVEEGKIYSRVLRTELLECLGDSDFLAKLHCVRQAFQVILSEAANRIFLAQSGRKILSALIVKARKNPKKFEDVFDEMIYFLEQTDHWDSTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPPSIQSVVSNRWLNSSFKETAVASSCWSVLKQKRQQMKISDGFFAHFYAICEHISPVLAWGFLGPRNSLYDLCCFFKNQVLFFLKDIFDFEKVRYSSIDTLAEDLSHLLIRRTELLVACLGADALRHATTCTSGPGHAVPNTLVEGKVQ", "length": 599 }, "evidence": [ { "id": "A0A8V0ZPP6", "url": "https://omabrowser.org/oma/group/A0A8V0ZPP6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4QQM5-1", "protein_name": "Mitoguardin 1", "gene_name": "Miga1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDETVSRSQFSLKTYAVRVFALPVSWYYSLSQIKFSPVAKKLFMVTAVSAVSVIFLAHHFKRRRGKQKGKVLPWEPEHLLLEHTRRAASEKGSSCSSSRQNLTLSLSSTKEKGSQCCNYPNGGLLSRYSGSAQSLGSVQSVNSCHSCACGNSNSWDKADDDDIRLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRSRQAEDEACSSVKLGAGDAIAEESVDDIISSEFIHKLEALLQRAYRLQEEFEATLGGSDPNSIANDTDKDTDMSLRETMDELGLPDAMNMDSADLFASATELAEQREAQQTFSLESFCPCPFYEEAMHLVEEGKIYSRVLRTEMLECLGDSDFLAKLHCIRQAFQLILAEADNRSFLAESGRKILSALIVKARKNPKKFQDVFDEMINFLEQTDHWDSTELELAARGVKNLNFYDVVLDFILMDSFEDLENPPTSIQSVVNNRWLNSSFKESAVASSCWSVLKQKRQQMKISDGFFAHFYAICEHVSPVLAWGFLGPRNSLYDLCCFFKNQVLFFLKDIFDFEKVRYSSIDTLAEDLTHLLIRRTELLVTCLGADALRHATTCTSGHSHAVPTALLEAKVQ", "length": 600 }, "evidence": [ { "id": "A0A8V0ZPP6", "url": "https://omabrowser.org/oma/group/A0A8V0ZPP6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPP6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 464, "end_pos": 466 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNU9-1", "uniprot_ac": "A0A8V0ZNU9", "uniprot_id": "A0A8V0ZNU9_CHICK", "mass": { "chemical_mass": 70284.0, "monoisotopic_mass": 70284.0 }, "refseq": { "ac": "XP_046758778", "name": "rho GTPase-activating protein 40 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758778" }, "gene_names": [ { "name": "ARHGAP40", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9" } ] }, { "name": "ARHGAP40", "type": "synonym", "evidence": [ { "id": "XP_046758778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758778" } ] }, { "name": "C20orf95", "type": "synonym", "evidence": [ { "id": "XP_046758778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758778" } ] } ], "protein_names": [ { "name": "Rho GTPase activating protein 40", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 40 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_046758778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758778" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046758778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758778" } ] }, { "annotation": "GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9#function" }, { "database": "UniProtKB", "id": "ARBA00055252", "url": "https://www.uniprot.org/uniprotkb/ARBA00055252#function" }, { "database": "UniProtKB", "id": "A0A8V0ZXK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXK8#function" }, { "database": "UniProtKB", "id": "A0A8V1A1K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1K8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGAP40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9", "locus": { "chromosome": "20", "start_pos": 4047747, "end_pos": 4092055, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023712", "url": "https://www.ensembl.org/id/ENSGALG00010023712" } ] } } ], "crossref": [ { "id": "A0A8V0ZNU9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04391", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04391", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419168", "url": "https://www.ncbi.nlm.nih.gov/gene/419168", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419168", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419168", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GDSGMKW", "url": "https://omabrowser.org/oma/group/GDSGMKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNU9", "url": "https://www.orthodb.org/?gene=A0A8V0ZNU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXK8", "url": "https://www.orthodb.org/?gene=A0A8V0ZXK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1K8", "url": "https://www.orthodb.org/?gene=A0A8V1A1K8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14963:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14963:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25442", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25442", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046758778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046758778", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1K8", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1K8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQLPQKSPLASPLSEDTTSRGDNLPMESFWLEVENIKQSSEAEQEECALADVKTQEEGEAEAEWLQDAGLSDLIGDHGSESDNALLSTLTKTQAAAVQRRLDTYSRSRRRKNKPPVRDVRDIFGVVGSGETGKEKEEPSPDLLLHNLRTANVQKPESQDYSCTVRNPGKEEVFNMDIAYSEQAAVLLKGSFLPESKRIKDGNVLTKFKIPKGRLGVTRIGDLSAQDMKKIPTLALIELTALCDVLGFELKRNKAAKLKTTEKRLFGVPLNTLLENDQKLLPNTKVPLLLQALLSCLEKRGLETEGILRVSGSQTRIKSLEQKLERDFYSGLFRWDEVHQNDVSGLLKRFIRELPAPLLTAEYLPAFAAVQNIPDLKQRLQALNLLILILPEPNRNTLKALLEFLSKVVSRENNNKMNLWNVSTVMAPNLFMHKGLPNKIPEGKEKQLAEGAADVVRMMIHYQDLLWTVSSFLVAQVRKLNESNSKRYQFCDKRLKNLLRKIHADKDKVEKNQAEPSKVVKVHASLLLKDSLEVHLNNATRVADVLRQFQKNLCQNGWNIVNTVNLLKCNNSMECTNLLLYEVGGNIGEHCLDPDTYLLDLYHINPHAEWIIKQNPSYPRMF", "length": 622, "header": "tr|A0A8V0ZNU9-1|A0A8V0ZNU9_CHICK Isoform 1 of Rho GTPase activating protein 40 OS=Gallus gallus OX=9031 GN=ARHGAP40 PE=4 SV=1 CANONICAL=A0A8V0ZNU9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9/entry#A0A8V0ZNU9-1", "sequence": { "sequence": "MSQLPQKSPLASPLSEDTTSRGDNLPMESFWLEVENIKQSSEAEQEECALADVKTQEEGEAEAEWLQDAGLSDLIGDHGSESDNALLSTLTKTQAAAVQRRLDTYSRSRRRKNKPPVRDVRDIFGVVGSGETGKEKEEPSPDLLLHNLRTANVQKPESQDYSCTVRNPGKEEVFNMDIAYSEQAAVLLKGSFLPESKRIKDGNVLTKFKIPKGRLGVTRIGDLSAQDMKKIPTLALIELTALCDVLGFELKRNKAAKLKTTEKRLFGVPLNTLLENDQKLLPNTKVPLLLQALLSCLEKRGLETEGILRVSGSQTRIKSLEQKLERDFYSGLFRWDEVHQNDVSGLLKRFIRELPAPLLTAEYLPAFAAVQNIPDLKQRLQALNLLILILPEPNRNTLKALLEFLSKVVSRENNNKMNLWNVSTVMAPNLFMHKGLPNKIPEGKEKQLAEGAADVVRMMIHYQDLLWTVSSFLVAQVRKLNESNSKRYQFCDKRLKNLLRKIHADKDKVEKNQAEPSKVVKVHASLLLKDSLEVHLNNATRVADVLRQFQKNLCQNGWNIVNTVNLLKCNNSMECTNLLLYEVGGNIGEHCLDPDTYLLDLYHINPHAEWIIKQNPSYPRMF", "length": 622, "header": "tr|A0A8V0ZNU9-1|A0A8V0ZNU9_CHICK Isoform 1 of Rho GTPase activating protein 40 OS=Gallus gallus OX=9031 GN=ARHGAP40 PE=4 SV=1 CANONICAL=A0A8V0ZNU9-1" }, "locus": { "chromosome": "20", "start_pos": 4064405, "end_pos": 4050281, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057811.1", "url": "https://www.ensembl.org/id/ENSGALT00010057811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035083.1", "url": "https://www.ensembl.org/id/ENSGALP00010035083.1" } ] } }, { "isoform_ac": "A0A8V0ZXK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9/entry#A0A8V0ZXK8-1", "sequence": { "sequence": "MDKIGKRGSGFARTRIPRPQVVLQPMQPACCSCSTRNCPCKMSQLPQKSPLASPLSEDTTSRGDNLPMESFWLEVENIKQSSEAEQEECALADVKTQEEGEAEAEWLQDAGLSDLIGDHGSESDNALLSTLTKTQAAAVQRRLDTYSRSRRRKNKPPVRDVRDIFGVVGSGETGKEKEEPSPDLLLHNLRTANVQKPESQDYSCTVRNPGKEEVFNMDIAYSEQAAVLLKGSFLPESKRIKDGNVLTKFKIPKGRLGVTRIGDLSAQDMKKIPTLALIELTALCDVLGFELKRNKAAKLKTTEKRLFGVPLNTLLENDQKLLPNTKVPLLLQALLSCLEKRGLETEGILRVSGSQTRIKSLEQKLERDFYSGLFRWDEVHQNDVSGLLKRFIRELPAPLLTAEYLPAFAAVQNIPDLKQRLQALNLLILILPEPNRNTLKALLEFLSKVVSRENNNKMNLWNVSTVMAPNLFMHKGLPNKIPEGKEKQLAEGAADVVRMMIHYQDLLWTVSSFLVAQVRKLNESNSKRYQFCDKRLKNLLRKIHADKDKVEKNQAEPSKVVKVHASLLLKDSLEVHLNNATRVADVLRQFQKNLCQNGWNIVNTVNLLKCNNSMECTNLLLYEVGGNIGEHCLDPDTYLLDLYHINPHAEWIIKQNPSYPRMF", "length": 663, "header": "tr|A0A8V0ZXK8-1|A0A8V0ZNU9_CHICK Computationally mapped isoform of Rho GTPase activating protein 40 OS=Gallus gallus OX=9031 GN=ARHGAP40 PE=4 SV=1 CANONICAL=A0A8V0ZNU9-1" }, "locus": { "chromosome": "20", "start_pos": 4073164, "end_pos": 4050281, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057796.1", "url": "https://www.ensembl.org/id/ENSGALT00010057796.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035076.1", "url": "https://www.ensembl.org/id/ENSGALP00010035076.1" } ] } }, { "isoform_ac": "A0A8V1A1K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9/entry#A0A8V1A1K8-1", "sequence": { "sequence": "MSSTRNCPCKMSQLPQKSPLASPLSEDTTSRGDNLPMESFWLEVENIKQSSEAEQEECALADVKTQEEGEAEAEWLQDAGLSDLIGDHGSESDNALLSTLTKTQAAAVQRRLDTYSRSRRRKNKPPVRDVRDIFGVVGSGETGKEKEEPSPDLLLHNLRTANVQKQSQDYSCTVRNPGKEEVFNMDIAYSEQAAVLLKGSFLPESKRIKDGNVLTKFKIPKGRLGVTRIGDLSAQDMKKIPTLALIELTALCDVLGFELKRNKAAKLKTTEKRLFGVPLNTLLENDQKLLPNTKVPLLLQALLSCLEKRGLETEGILRVSGSQTRIKSLEQKLERDFYSGLFRWDEVHQNDVSGLLKRFIRELPAPLLTAEYLPAFAAVQNIPDLKQRLQALNLLILILPEPNRNTLKALLEFLSKVVSRENNNKMNLWNVSTVMAPNLFMHKGLPNKIPEGKEKQLAEGAADVVRMMIHYQDLLWTVSSFLVAQVRKLNESNSKRYQFCDKRLKNLLRKIHADKDKVEKNQAEPSKVVKVHASLLLKDSLEVHLNNATRVADVLRQFQKNLCQNGWNIVNTVNLLKCNNSMECTNLLLYEVGGNIGEHCLDPDTYLLDLYHINPHAEWIIKQNPSYPRMF", "length": 631, "header": "tr|A0A8V1A1K8-1|A0A8V0ZNU9_CHICK Computationally mapped isoform of Rho GTPase activating protein 40 OS=Gallus gallus OX=9031 GN=ARHGAP40 PE=4 SV=2 CANONICAL=A0A8V0ZNU9-1" }, "locus": { "chromosome": "20", "start_pos": 4086276, "end_pos": 4050281, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057802.1", "url": "https://www.ensembl.org/id/ENSGALT00010057802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035079.1", "url": "https://www.ensembl.org/id/ENSGALP00010035079.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419168", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419168", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZWF9-1", "protein_name": "Rho GTPase activating protein 40", "gene_name": "Arhgap40", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEPSLLPAAQMEGLALLPLASPCPRIPRARISRQPGRWAHLGCSPGPSTGPTNLPRYPLKPRPADCAYSRLSWAESLSMDGFWPGVERIQQRGERKKEDCGGSRSQLLEGDAESQWLQDTGLAGLVGGLGLDDDHQGLLSTLTQTQVAAVCRRLDIYARSARRRQKAPVRDVRDIFGVFTSREAAPENGDSGMKWTEFNSEDSASPLRPAGGPQEPAGMEEVFNMESAYSEQAAVLLQRTWSSPEGARAWGKGCLPRFRIPKGRLGVTRIGDLSSRDMKKILPLALIELTALYDILGLDLKRSKGRKWKGADSGLFGVPLHSLLEADHRVFPSTQVPLLLQALLSCLEKRGLDTEGILRVPGSQARVKGLEQKLERDFYAGLVSWDKVHPNDASDLLKRFLRKLPAPLLTAEYLPAFAAVPNIPDLKQRLQALHLLVLLLPEPNRNTLKALLEFLRKVAAQEQHNKMTLWNVSTVMAPNLFLPRGRPPKLAQGEKQLAEGAAEVVCMMVQYQDLLWTVASFLVAQVRKLNDSNCRRSQLCDGGLKTWLRRTHVDRDKARNGLEATPKVATIQVPATGPSMDLLQVPLSPSTRVTHVLKLFTEHLNPGSQPEEGSETSNSLLSDNTKKKPATFLVYEVGGNIGEHRLDPDAYLLDLYRANPHGEWVIRQSPT", "length": 672 }, "evidence": [ { "id": "A0A8V0ZNU9", "url": "https://omabrowser.org/oma/group/A0A8V0ZNU9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q6X9-1", "protein_name": "Rho GTPase-activating protein 40", "gene_name": "Arhgap40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEPSLLPAAKMEGLALLPLTSPCPRIPRARISRQPGRWAHLGCSPGLSTGPTNLQQHPQKPRPADCSHSRLSWAESLSMDGFWMEVERIQQRAEVKKEDCGEGRSQLLEGDTESQWLQDTGLSGLAGGLGLDGDHQGLLSTLTQTQVAAVCRRLDIYARSARRRQKAPVRDVRDIFGVFTSRELAPENGVSGMKWTKINSEDSASPLRSAEPGGPQELAGMEEVFNMDSAYSEQAAVLLQRAWPSPGGTTAWGKGPLPRFRIPKGRLGVTRIGDLSSRDMKKIPPLALIELTALYDILGLDLKRCKGGKWKGPDSGLFGVPLHSLLEADHRVFPSTQVPLLLQALLSCLEKRGLDTEGILRVPGSQARVKGLEQKLERDFYAGLVSWDKVHPNDASDLLKRFLRKLPVPLLTAEYLPAFASVPDIPDLKQRLQALHLLVLLLPEPNRNTLKALLEFLRKVAAQEQHNKMTLWNVSTVMVPSLFLPRGRPPKLTKGGKQLAEGAAEVVCMMVQYQDLLWTVASFLVAQVRKLNDSNGRRSQLCDGGLKTWLWRTHVDRDKAGEGLEATPKVAKIQVQATWPSMDLLQVPLNPSTRVTHVLKLFTEHLNPGSQPEEGSENPNSLLSHNTKPVTFLVYEVGGNIGERRLDPDAYLLDLYRANPHGEWVIRQSPT", "length": 672 }, "evidence": [ { "id": "A0A8V0ZNU9", "url": "https://omabrowser.org/oma/group/A0A8V0ZNU9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5TG30-1", "protein_name": "Rho GTPase-activating protein 40", "gene_name": "ARHGAP40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPALLPAAQMERLAPGPLASPCPRIPRARIARRCAQRWADLGCSSGPSSGRMDQLPQKNLLRLHPAGSAGCSTGVESSSMDGFWMEVEQIQQRDELREEDSGGNEGQLPEEGEAESQWLQDTGLSGLLGGLGLDGDHQELLSTLTQTQVAAVCRRLDIYARSVRRQHKTPVRDVRDVFGVFNSGKMSSENGDSGMKGAQLSSGASKFPPAAEPGGLQEQAGREEAFNMDSAYSEQAAVLLQRSRPSRGGTSAWGKCSLPKFTVPKGRLGVTRIGDLSLQDMRKVPSLALIELTALCDILGLDLKRSKAGKWKAAETRLFGVPLDSLLEADHKVLPSTQVPLVLQALLSCLEKRGLDMEGILRVPGSQARVKGLEQKLERDFYAGLFSWDEVHHNDASDLLKRFIRKLPTPLLTAEYLPAFAVVPNIPNLKQRLQVLHLLILILPEPNRNALKALLEFLRKVVAREQHNKMTLRNVSTVMAPNLFLHQGRPPKLPKGKEKQLAEGAAEVVQIMVHYQDLLWTVASFLVAQVRKLNDSSSRRPQLCDAGLKTWLRRMHADRDKAGDGLEATPKVAKIQVVWPIKDPLKVPLTPSTKVAHVLRQFTEHLSPGSKGQEDSEDMDSLLLHHRSMESANILLYEVGGNINEHRLDPDAYLLDLYRANPHGEWVLKQNPT", "length": 675 }, "evidence": [ { "id": "A0A8V0ZNU9", "url": "https://omabrowser.org/oma/group/A0A8V0ZNU9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9" } ], "pmid": "" }, { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9" } ], "pmid": "" }, { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU9" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 268, "end_pos": 467, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 421, "end_pos": 423 }, { "start_pos": 481, "end_pos": 483 }, { "start_pos": 538, "end_pos": 540 }, { "start_pos": 570, "end_pos": 572 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZR23-1", "uniprot_ac": "A0A8V0ZR23", "uniprot_id": "A0A8V0ZR23_CHICK", "mass": { "chemical_mass": 44444.0, "monoisotopic_mass": 44444.0 }, "refseq": { "ac": "XP_046786694", "name": "ADP-ribosylation factor GTPase-activating protein 1 isoform X22", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046786694" }, "gene_names": [ { "name": "ARFGAP1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23" } ] }, { "name": "ARFGAP1", "type": "synonym", "evidence": [ { "id": "XP_046786694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046786694" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor GTPase-activating protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor 1 GTPase-activating protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor GTPase-activating protein 1 isoform X22", "type": "synonym", "evidence": [ { "id": "XP_046786694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046786694" } ] }, { "name": "ARF1-directed GTPase-activating protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052592.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046786694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046786694" } ] }, { "annotation": "GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS5#function" }, { "database": "UniProtKB", "id": "ARBA00058112", "url": "https://www.uniprot.org/uniprotkb/ARBA00058112#function" }, { "database": "UniProtKB", "id": "A0A8V0ZR23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23#function" }, { "database": "UniProtKB", "id": "A0A8V0ZSY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZU27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU27#function" }, { "database": "UniProtKB", "id": "A0A8V0ZYH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYH4#function" }, { "database": "UniProtKB", "id": "A0A8V0ZYJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYJ0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZYJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYJ5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARFGAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23", "locus": { "chromosome": "20", "start_pos": 9145220, "end_pos": 9127422, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023048", "url": "https://www.ensembl.org/id/ENSGALG00010023048" } ] } } ], "crossref": [ { "id": "A0A8V0ZR23", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR23", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08830", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08830", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419241", "url": "https://www.ncbi.nlm.nih.gov/gene/419241", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKS5", "url": "https://www.orthodb.org/?gene=A0A8V0ZKS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR23", "url": "https://www.orthodb.org/?gene=A0A8V0ZR23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSY2", "url": "https://www.orthodb.org/?gene=A0A8V0ZSY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU27", "url": "https://www.orthodb.org/?gene=A0A8V0ZU27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYH4", "url": "https://www.orthodb.org/?gene=A0A8V0ZYH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYJ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZYJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYJ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZYJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46395", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46395", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46395:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46395:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807878", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811434", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046786694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046786694", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGKHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNSKFREFLESQDDYDPCWSMQEKYNSKAAALFRDQVATVAEGKEWSLETSPARNWTPPQPKTSLSSTHRSSAGPPQNTTASSDKAFEDWLNDDVNSYQGGQENRYVGFGNTVTPPKKEDDFLNNAMSSLYSGWSSFTTGASKIASAAKEGATRFGSQASQKVKEGKIFEEVTVGVSQLASKVQGVGSKGWRDVTTFFSGKPDDHSERPAEGDSYQNSGGEGYQNNAVDQSFWETFGNSDPPKAHKSPSSESWTYVDNSTEKKSSDSWDVWGSGTVSNNKNSNSDSWENWETNWENTGGESKAKKPPKATKKASSADDKWDDW", "length": 401, "header": "tr|A0A8V0ZR23-1|A0A8V0ZR23_CHICK Isoform 1 of ADP-ribosylation factor GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=ARFGAP1 PE=1 SV=1 CANONICAL=A0A8V0ZR23-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23/entry#A0A8V0ZKS5-1", "sequence": { "sequence": "MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGKHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNSKFREFLESQDDYDPCWSMQEKYNSKAAALFRDQVATVAEGKEWSLETSPARNWTPPQPKTSLSSTHRSAGPPQNTTASSDKAFEDWLNDDVNSYQGGQENRYVGFGNTVTPPKKEDDFLNNAMSSLYSGWSSFTTGASKIASAAKEGATRFGSQASQKASELGQTLNENVLKPAQEKVTLELVQGVGSKGWRDVTTFFSGKPDDHSERPAEGDSYQNSGGEGYQNNAVDQSFWETFGNSDPPKAHKSPSSESWTYVDNSTEKKSSDSWDVWGSGTVSNNKNSNSDSWENWETNWENTGGESKAKKPPKATKKASSADDKWDDW", "length": 404, "header": "tr|A0A8V0ZKS5-1|A0A8V0ZR23_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=ARFGAP1 PE=1 SV=1 CANONICAL=A0A8V0ZR23-1" }, "locus": { "chromosome": "20", "start_pos": 9141261, "end_pos": 9130075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056151.1", "url": "https://www.ensembl.org/id/ENSGALT00010056151.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033974.1", "url": "https://www.ensembl.org/id/ENSGALP00010033974.1" } ] } }, { "isoform_ac": "A0A8V0ZR23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23/entry#A0A8V0ZR23-1", "sequence": { "sequence": "MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGKHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNSKFREFLESQDDYDPCWSMQEKYNSKAAALFRDQVATVAEGKEWSLETSPARNWTPPQPKTSLSSTHRSSAGPPQNTTASSDKAFEDWLNDDVNSYQGGQENRYVGFGNTVTPPKKEDDFLNNAMSSLYSGWSSFTTGASKIASAAKEGATRFGSQASQKVKEGKIFEEVTVGVSQLASKVQGVGSKGWRDVTTFFSGKPDDHSERPAEGDSYQNSGGEGYQNNAVDQSFWETFGNSDPPKAHKSPSSESWTYVDNSTEKKSSDSWDVWGSGTVSNNKNSNSDSWENWETNWENTGGESKAKKPPKATKKASSADDKWDDW", "length": 401, "header": "tr|A0A8V0ZR23-1|A0A8V0ZR23_CHICK Isoform 1 of ADP-ribosylation factor GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=ARFGAP1 PE=1 SV=1 CANONICAL=A0A8V0ZR23-1" }, "locus": { "chromosome": "20", "start_pos": 9141261, "end_pos": 9130075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056131.1", "url": "https://www.ensembl.org/id/ENSGALT00010056131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033956.1", "url": "https://www.ensembl.org/id/ENSGALP00010033956.1" } ] } }, { "isoform_ac": "A0A8V0ZSY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23/entry#A0A8V0ZSY2-1", "sequence": { "sequence": "MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGKHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNSKFREFLESQDDYDPCWSMQEKYNSKAAALFRDQVATVAEGKEWSLETSPARNWTPPQPKTSLSSTHRSAGPPQNTTASSDKAFEDWLNDDVNSYQGGQENRYVGFGNTVTPPKKEDDFLNNAMSSLYSGWSSFTTGASKIASAAKEGATRFGSQASQKASELGQTLNENVLKPAQEKVKEGKIFEEVTVGVSQLASKVQGVGSKGWRDVTTFFSGKPDDHSERPAEGDSYQNNAVDQSFWETFGNSDPPKAHKSPSSESWTYVDNSTEKKSSDSWDVWGSGTVSNNKNSNSDSWENWETNWENTGGESKAKKPPKATKKASSADDKWDDW", "length": 411, "header": "tr|A0A8V0ZSY2-1|A0A8V0ZR23_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=ARFGAP1 PE=1 SV=1 CANONICAL=A0A8V0ZR23-1" }, "locus": { "chromosome": "20", "start_pos": 9141261, "end_pos": 9130075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056115.1", "url": "https://www.ensembl.org/id/ENSGALT00010056115.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033943.1", "url": "https://www.ensembl.org/id/ENSGALP00010033943.1" } ] } }, { "isoform_ac": "A0A8V0ZU27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23/entry#A0A8V0ZU27-1", "sequence": { "sequence": "MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGKHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNSKFREFLESQDDYDPCWSMQEKYNSKAAALFRDQVATVAEGKEWSLETSPARNWTPPQPKTSLSSTHRSAGPPQNTTASSDKAFEDWLNDDVNSYQGGQENRYVGFGNTVTPPKKEDDFLNNAMSSLYSGWSSFTTGASKIASAAKEGATRFGSQASQKVQGVGSKGWRDVTTFFSGKPDDHSERPAEGDSYQNSGGEGYQNNAVDQSFWETFGNSDPPKAHKSPSSESWTYVDNSTEKKSSDSWDVWGSGTVSNNKNSNSDSWENWETNWENTGGESKAKKPPKATKKASSADDKWDDW", "length": 380, "header": "tr|A0A8V0ZU27-1|A0A8V0ZR23_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=ARFGAP1 PE=1 SV=1 CANONICAL=A0A8V0ZR23-1" }, "locus": { "chromosome": "20", "start_pos": 9141261, "end_pos": 9130075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056154.1", "url": "https://www.ensembl.org/id/ENSGALT00010056154.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033977.1", "url": "https://www.ensembl.org/id/ENSGALP00010033977.1" } ] } }, { "isoform_ac": "A0A8V0ZYH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23/entry#A0A8V0ZYH4-1", "sequence": { "sequence": "MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGKHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNSKFREFLESQDDYDPCWSMQEKYNSKAAALFRDQVATVAEGKEWSLETSPARNWTPPQPKTSLSSTHRSAGPPQNTTASSDKAFEDWLNDDVNSYQGGQENRYVGFGNTVTPPKKEDDFLNNAMSSLYSGWSSFTTGASKIASAAKEGATRFGSQASQKFWGYKQQPEPGVGSKGWRDVTTFFSGKPDDHSERPAEGDSYQNSGGEGYQNNAVDQSFWETFGNSDPPKAHKSPSSESWTYVDNSTEKKSSDSWDVWGSGTVSNNKNSNSDSWENWETNWENTGGESKAKKPPKATKKASSADDKWDDW", "length": 388, "header": "tr|A0A8V0ZYH4-1|A0A8V0ZR23_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=ARFGAP1 PE=1 SV=1 CANONICAL=A0A8V0ZR23-1" }, "locus": { "chromosome": "20", "start_pos": 9141261, "end_pos": 9130075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056122.1", "url": "https://www.ensembl.org/id/ENSGALT00010056122.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033950.1", "url": "https://www.ensembl.org/id/ENSGALP00010033950.1" } ] } }, { "isoform_ac": "A0A8V0ZYJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23/entry#A0A8V0ZYJ0-1", "sequence": { "sequence": "MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGKHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNSKFREFLESQDDYDPCWSMQEKYNSKAAALFRDQVATVAEGKEWSLETSPARNWTPPQPKTSLSSTHRSAGPPQNTTASSDKAFEDWLNDDVNSYQGGQENRYVGFGNTVTPPKKEDDFLNNAMSSLYSGWSSFTTGASKIASAAKEGATRFGSQASQKFWGYKQQPEPASELGQTLNENVLKPAQEKVKEGKIFEEVTVGVSQLASKVQGVGSKGWRDVTTFFSGKPDDHSERPAEGDSYQNSGGEGYQNNAVDQSFWETFGNSDPPKAHKSPSSESWTYVDNSTEKKSSDSWDVWGSGTVSNNKNSNSDSWENWETNWENTGGESKAKKPPKATKKASSADDKWDDW", "length": 429, "header": "tr|A0A8V0ZYJ0-1|A0A8V0ZR23_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=ARFGAP1 PE=1 SV=1 CANONICAL=A0A8V0ZR23-1" }, "locus": { "chromosome": "20", "start_pos": 9141261, "end_pos": 9130075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056142.1", "url": "https://www.ensembl.org/id/ENSGALT00010056142.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033965.1", "url": "https://www.ensembl.org/id/ENSGALP00010033965.1" } ] } }, { "isoform_ac": "A0A8V0ZYJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23/entry#A0A8V0ZYJ5-1", "sequence": { "sequence": "MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGKHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNSKFREFLESQDDYDPCWSMQEKYNSKAAALFRDQVATVAEGKEWSLETSPARNWTPPQPKTSLSSTHRSSAGPPQNTTASSDKAFEDWLNDDVNSYQGGQENRYVGFGNTVTPPKKEDDFLNNAMSSLYSGWSSFTTGASKIASAAKEGATRFGSQASQKASELGQTLNENVLKPAQEKVKEGKIFEEVTVGVSQLASKVQGVGSKGWRDVTTFFSGKPDDHSERPAEGDSYQNSGGEGYQNNAVDQSFWETFGNSDPPKAHKSPSSESWTYVDNSTEKKSSDSWDVWGSGTVSNNKNSNSDSWENWETNWENTGGESKAKKPPKATKKASSADDKWDDW", "length": 420, "header": "tr|A0A8V0ZYJ5-1|A0A8V0ZR23_CHICK Computationally mapped isoform of ADP-ribosylation factor GTPase-activating protein 1 OS=Gallus gallus OX=9031 GN=ARFGAP1 PE=1 SV=1 CANONICAL=A0A8V0ZR23-1" }, "locus": { "chromosome": "20", "start_pos": 9141261, "end_pos": 9130075, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056147.1", "url": "https://www.ensembl.org/id/ENSGALT00010056147.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033970.1", "url": "https://www.ensembl.org/id/ENSGALP00010033970.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6807878", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807878", "resource": "Reactome", "description": "COPI-mediated anterograde transport" }, { "id": "R-GGA-6811434", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811434", "resource": "Reactome", "description": "COPI-dependent Golgi-to-ER retrograde traffic" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR23" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR23", "url": 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Binds (AU)-rich elements (ARE) in the 3'-UTR of target mRNA to enhance their stability. Upon metabolic acidosis, stabilizes the mRNA encoding SLC12A1 a cotransporter involved in transepithelial NH4(+) reabsorption in the medullary thick ascending limb in kidney. In response to acidosis, also participates to the adaptive increase in renal ammoniagenesis by stabilizing the mRNAs of enzymes involved in glutamine catabolism. By the same mechanism, it also regulates the expression of the antiapoptotic protein BCL2. Beside its mRNA stabilization activity, also catalyzes the reduction of orthoquinones such as 1,2-naphthoquinone or 9,10-phenanthrenequinone in the presence of NADPH in vitro and could be involved in the detoxification of xenobiotics and protection against oxidative stress.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZZ17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ17#function" }, { "database": "UniProtKB", "id": "ARBA00094201", "url": "https://www.uniprot.org/uniprotkb/ARBA00094201#function" }, { "database": "UniProtKB", "id": "A0A8V0ZQ45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ45#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ45" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ45", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZ17", "url": "https://www.orthodb.org/?gene=A0A8V0ZZ17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44154", "url": 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"database": "Ensembl Peptide", "id": "ENSGALP00010035550.1", "url": "https://www.ensembl.org/id/ENSGALP00010035550.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ45" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ45" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", 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[], "interactions": [], "reactions": [ { "id": "14269", "name": "", "equation": "2 a quinone + NADPH + H(+) = 2 a 1,4-benzosemiquinone + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZQ45-1", "A0A8V0XPJ0-1", "A0A8V0ZQV0-1" ], "evidence": [ { "id": "14269", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14269" } ] }, { "id": "85243", "name": "", "equation": "2 1,2-naphthoquinone + NADPH + H(+) = 2 1,2-naphthosemiquinone + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZQ45-1" ], "evidence": [ { "id": "85243", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/85243" } ] }, { "id": "85247", "name": "", "equation": "2 9,10-phenanthroquinone + NADPH + H(+) = 2 9,10-phenanthrosemiquinone + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZQ45-1" ], "evidence": [ { "id": "85247", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/85247" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XPJ0", "gene_name": "VAT1L", "activity": [ { "ec_number": "1.6.5.5", "activity": "2 1,2-naphthoquinone + NADPH + H(+) = 2 1,2-naphthosemiquinone + NADP(+).", "evidence": [ { "id": "A0A8V0XPJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPJ0" } ] }, { "ec_number": "1.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V0XPJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPJ0" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ45", "gene_name": "CRYZ", "activity": [ { "ec_number": "1.6.5.5", "activity": "2 1,2-naphthoquinone + NADPH + H(+) = 2 1,2-naphthosemiquinone + NADP(+).", "evidence": [ { "id": "A0A8V0ZQ45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ45" } ] }, { "ec_number": "1.6.5.5", "activity": 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This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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}, { "id": "A0A8V0ZZ92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGPRPDKHGIKITELFPLLKGGSPKNHLPQNLNGSVERRCASDKERREEENASHENGASQEIFEAEMAINSAENLLPTFKDILGRMTNQVCKPSTSEMIIIDTQEDLLVKELTTLKTTKRLLWLLLQTREQKQIDSKNIEALIQKLSENETHNMSLRRKIVEREEHVKELSSRIQLKKVPVLKEEYLSRPVNTIEAHLQYQIQRKEVENDELRLKTQTLEKKIAEWKLQIGEYKRQMLALKKTSEQKKAYLRRAIRSQKQKTECFEEAVENLTSRVKEREVKLSEILSASDVWKKQHDRMVEEKTMLAVQTEDLKKQITSLSEDLKRKEEFRRKASEELLGKLNSVNSENEKIYLENEKLKACLAALEISTVSVENDLLCLQEKTKLQENIVEDCKNQVRELKAEVEVLKSRYKIIFSENKSIRESKCLEVYEEEDGVNSVGNCSLEEENSTIQKKYEHLKRILENMQFQNEELAYLIKKEDESLQCSKLQLEEKIAEYNSLTKQLESALEEGRKMVAEEFEKMSYLEQALQTKMLVLENEVRERQEEKKELLCAFHRNEKHHEVCLKELENSLQRSENKKQSIQNYVQFLKTSYITMFG", "length": 601, "header": "tr|A0A8V0ZRQ9-1|A0A8V0ZRQ9_CHICK Isoform 1 of Outer dense fiber of sperm tails 2 like OS=Gallus gallus OX=9031 GN=ODF2L PE=3 SV=1 CANONICAL=A0A8V0ZRQ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9/entry#A0A8V0ZLE7-1", "sequence": { "sequence": "MSLRRKIVEREEHVKELSSRIQLKKVPVLKEEYLSRPVNTIEAHLQYQIQRKEVENDELRLKTQTLEKKIAEWKLQIGEYKRQMLALKKTSEQKKAYLRRAIRSQKQKTECFEEAVENLTSRVKEREVKLSEILSASDVWKKQHDRMVEEKTMLAVQTEDLKKQITSLSEDLKRKEEFRRKASEELLGKLNSVNSENEKIYLENEKLKACLAALEISTVSVENDLLCLQEKTKLQENIVEDCKNQVRDKAEPKLKVLEHVCGLLKAAEGELRGFQENLVYWERINTQKCKTPRELQVQEEDGVNSVGNCSLEEENSTIQKKYEHLKRILENMQFQNEELAYLIKKEDESLQCSKLQLEEKIAEYNSLTKQLESALEEGRKMVAEEFEKMSYLEQALQTKMLVLENEVRERQEEKKELLCAFHRNEKHHEVCLKELENSLQRSENKKQSIQNYVQFLKTSYITMFG", "length": 465, "header": "tr|A0A8V0ZLE7-1|A0A8V0ZRQ9_CHICK Computationally mapped isoform of Outer dense fiber of sperm tails 2 like OS=Gallus gallus OX=9031 GN=ODF2L PE=3 SV=1 CANONICAL=A0A8V0ZRQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15739211, "end_pos": 15725670, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056448.1", "url": "https://www.ensembl.org/id/ENSGALT00010056448.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034191.1", "url": "https://www.ensembl.org/id/ENSGALP00010034191.1" } ] } }, { "isoform_ac": "A0A8V0ZLG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9/entry#A0A8V0ZLG7-1", "sequence": { "sequence": "MWGPRPDKHGIKITELFPLLKGGSPKNHLPQNLNGSVERRCASDKERREEENASHENGASQEIFEAEMAINSAENLLPTFKDILGRMTNQVCKPSTSEMIIIDTQEDLLVKELTTLKTTKRLLWLLLQTREQKQIDSKNIEALIQKLSENETHNMVPVLKEEYLSRPVNTIEAHLQYQIQRKEVENDELRLKTQTLEKKIAEWKLQIGEYKRQMLALKKTSEQKKAYLRRAIRSQKQKTECFEEAVENLTSRVKEREVKLSEILSASDVWKKQHDRMVEEKTMLAVQTEDLKKQITSLSEDLKRKEEFRRKASEELLGKLNSVNSENEKIYLENEKLKACLAALEISTVSVENDLLCLQEKTKLQENIVEDCKNQVRELKAEVEVLKSRYKIIFSENKSIRESKCLEVYEEEDGVNSVGNCSLEEENSTIQKKYEHLKRILENMQFQNEELAYLIKKEDESLQCSKLQLEEKIAEYNSLTKQLESALEEGRKMVAEEFEKMSYLEQALQTKMLVLENEVRERQEEKKELLCAFHRNEKHHEVCLKELENSLQRSENKKQSIQNYVQFLKTSYITMFG", "length": 577, "header": "tr|A0A8V0ZLG7-1|A0A8V0ZRQ9_CHICK Computationally mapped isoform of Outer dense fiber of sperm tails 2 like OS=Gallus gallus OX=9031 GN=ODF2L PE=3 SV=1 CANONICAL=A0A8V0ZRQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15739211, "end_pos": 15722975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056471.1", "url": "https://www.ensembl.org/id/ENSGALT00010056471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034214.1", "url": "https://www.ensembl.org/id/ENSGALP00010034214.1" } ] } }, { "isoform_ac": "A0A8V0ZLH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9/entry#A0A8V0ZLH2-1", "sequence": { "sequence": "MWGPRPDKHGIKITELFPLLKGGSPKNHLPQNLNGSVERRCASDKERREEENASHENGASQEIFEAEMAINSAENLLPTFKDILGRMTNQVCKPSTSEMIIIDTQEDLLVKELTTLKTTKRLLWLLLQTREQKQIDSKNIEALIQKLSENETHNMSLRRKIVEREEHVKELSSRIQLKKVPVLKEEYLSRPVNTIEAHLQYQIQRKEVENDELRLKTQTLEKKIAEWKLQIGEYKRQMLALKKTSEQKKAYLRRAIRSQKQKTECFEEAVENLTSRVKEREVKLSEILSASDVWKKQHDRMVEEKTMLAVQTEDLKKQITSLSEDLKRKEEFRRKASEELLGKLNSVNSENEKIYLENEKLKACLAALEISTVSVENDLLCLQEKTKLQENIVEDCKNQEEDGVNSVGNCSLEEENSTIQKKYEHLKRILENMQFQNEELAYLIKKEDESLQCSKLQLEEKIAEYNSLTKQLESALEEGRKMVAEEFEKMSYLEQALQTKMLVLENEVRERQEEKKELLCAFHRNEKHHEVCLKELENSLQRSENKKQSIQNYVQFLKTSYITMFG", "length": 566, "header": "tr|A0A8V0ZLH2-1|A0A8V0ZRQ9_CHICK Computationally mapped isoform of Outer dense fiber of sperm tails 2 like OS=Gallus gallus OX=9031 GN=ODF2L PE=3 SV=1 CANONICAL=A0A8V0ZRQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15739211, "end_pos": 15722975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056476.1", "url": "https://www.ensembl.org/id/ENSGALT00010056476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034219.1", "url": "https://www.ensembl.org/id/ENSGALP00010034219.1" } ] } }, { "isoform_ac": "A0A8V0ZRQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9/entry#A0A8V0ZRQ9-1", "sequence": { "sequence": "MWGPRPDKHGIKITELFPLLKGGSPKNHLPQNLNGSVERRCASDKERREEENASHENGASQEIFEAEMAINSAENLLPTFKDILGRMTNQVCKPSTSEMIIIDTQEDLLVKELTTLKTTKRLLWLLLQTREQKQIDSKNIEALIQKLSENETHNMSLRRKIVEREEHVKELSSRIQLKKVPVLKEEYLSRPVNTIEAHLQYQIQRKEVENDELRLKTQTLEKKIAEWKLQIGEYKRQMLALKKTSEQKKAYLRRAIRSQKQKTECFEEAVENLTSRVKEREVKLSEILSASDVWKKQHDRMVEEKTMLAVQTEDLKKQITSLSEDLKRKEEFRRKASEELLGKLNSVNSENEKIYLENEKLKACLAALEISTVSVENDLLCLQEKTKLQENIVEDCKNQVRELKAEVEVLKSRYKIIFSENKSIRESKCLEVYEEEDGVNSVGNCSLEEENSTIQKKYEHLKRILENMQFQNEELAYLIKKEDESLQCSKLQLEEKIAEYNSLTKQLESALEEGRKMVAEEFEKMSYLEQALQTKMLVLENEVRERQEEKKELLCAFHRNEKHHEVCLKELENSLQRSENKKQSIQNYVQFLKTSYITMFG", "length": 601, "header": "tr|A0A8V0ZRQ9-1|A0A8V0ZRQ9_CHICK Isoform 1 of Outer dense fiber of sperm tails 2 like OS=Gallus gallus OX=9031 GN=ODF2L PE=3 SV=1 CANONICAL=A0A8V0ZRQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15739211, "end_pos": 15722975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056467.1", "url": "https://www.ensembl.org/id/ENSGALT00010056467.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034210.1", "url": "https://www.ensembl.org/id/ENSGALP00010034210.1" } ] } }, { "isoform_ac": "A0A8V0ZTQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9/entry#A0A8V0ZTQ1-1", "sequence": { "sequence": "MRFRQREKQVCKPSTSEMIIIDTQEDLLVKELTTLKTTKRLLWLLLQTREQKQIDSKNIEALIQKLSENETHNMSLRRKIVEREEHVKELSSRIQLKKVPVLKEEYLSRPVNTIEAHLQYQIQRKEVENDELRLKTQTLEKKIAEWKLQIGEYKRQMLALKKTSEQKKAYLRRAIRSQKQKTECFEEAVENLTSRVKEREVKLSEILSASDVWKKQHDRMVEEKTMLAVQTEDLKKQITSLSEDLKRKEEFRRKASEELLGKLNSVNSENEKIYLENEKLKACLAALEISTVSVENDLLCLQEKTKLQENIVEDCKNQVRELKAEVEVLKSRYKIIFSENKSIRESKCLEVYEVRDKAEPKLKVLEHVCGLLKAAEGELRGFQENLVYWERINTQKCKTPRELQVQEEDGVNSVGNCSLEEENSTIQKKYEHLKRILENMQFQNEELAYLIKKEDESLQCSKLQLEEKIAEYNSLTKQLESALEEGRKMVAEEFEKMSYLEQALQTKMLVLENEVRERQEEKKELLCAFHRNEKHHEVCLKELENSLQRSENKKQSIQNYVQFLKTSYITMFG", "length": 573, "header": "tr|A0A8V0ZTQ1-1|A0A8V0ZRQ9_CHICK Computationally mapped isoform of Outer dense fiber of sperm tails 2 like OS=Gallus gallus OX=9031 GN=ODF2L PE=3 SV=1 CANONICAL=A0A8V0ZRQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15739211, "end_pos": 15723094, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056459.1", "url": "https://www.ensembl.org/id/ENSGALT00010056459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034202.1", "url": "https://www.ensembl.org/id/ENSGALP00010034202.1" } ] } }, { "isoform_ac": "A0A8V0ZZ71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9/entry#A0A8V0ZZ71-1", "sequence": { "sequence": "MESNMLWRTSTAHSDSKNIEALIQKLSENETHNMSLRRKIVEREEHVKELSSRIQLKKVPVLKEEYLSRPVNTIEAHLQYQIQRKEVENDELRLKTQTLEKKIAEWKLQIGEYKRQMLALKKTSEQKKAYLRRAIRSQKQKTECFEEAVENLTSRVKEREVKLSEILSASDVWKKQHDRMVEEKTMLAVQTEDLKKQITSLSEDLKRKEEFRRKASEELLGKLNSVNSENEKIYLENEKLKACLAALEISTVSVENDLLCLQEKTKLQENIVEDCKNQVRELKAEVEVLKSRYKIIFSENKSIRESKCLEVYEVRDKAEPKLKVLEHVCGLLKAAEGELRGFQENLVYWERINTQKCKTPRELQVQEEDGVNSVGNCSLEEENSTIQKKYEHLKRILENMQFQNEELAYLIKKEDESLQCSKLQLEEKIAEYNSLTKQLESALEEGRKMVAEEFEKMSYLEQALQTKMLVLENEVRERQEEKKELLCAFHRNEKHHEVCLKELENSLQRSENKKQSIQNYVQFLKTSYITMFG", "length": 533, "header": "tr|A0A8V0ZZ71-1|A0A8V0ZRQ9_CHICK Computationally mapped isoform of Outer dense fiber of sperm tails 2 like OS=Gallus gallus OX=9031 GN=ODF2L PE=3 SV=1 CANONICAL=A0A8V0ZRQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15739211, "end_pos": 15724760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056455.1", "url": "https://www.ensembl.org/id/ENSGALT00010056455.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034198.1", "url": "https://www.ensembl.org/id/ENSGALP00010034198.1" } ] } }, { "isoform_ac": "A0A8V0ZZ76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9/entry#A0A8V0ZZ76-1", "sequence": { "sequence": "MLTREKRCVVPVTPREEGKLCSLILPYKNDCHRTTKAAQGGKYFTELSKESDDPEQQEETWKKMWGPRPDKHGIKITELFPLLKGGSPKNHLPQNLNGSVERRCASDKERREEENASHENGASQEIFEAEMAINSAENLLPTFKDILGRMTNVCKPSTSEMIIIDTQEDLLVKELTTLKTTKRLLWLLLQTREQKQIDSKNIEALIQKLSENETHNMSLRRKIVEREEHVKELSSRIQLKKVPVLKEEYLSRPVNTIEAHLQYQIQRKEVENDELRLKTQTLEKKIAEWKLQIGEYKRQMLALKKTSEQKKAYLRRAIRSQKQKTECFEEAVENLTSRVKEREVKLSEILSASDVWKKQHDRMVEEKTMLAVQTEDLKKQITSLSEDLKRKEEFRRKASEELLGKLNSVNSENEKIYLENEKLKACLAALEISTVSVENDLLCLQEKTKLQENIVEDCKNQVRELKAEVEVLKSRYKIIFSENKSIRESKCLEVYEVRDKAEPKLKVLEHVCGLLKAAEGELRGFQENLVYWERINTQKCKTPRELQVQEEDGVNSVGNCSLEEENSTIQKKYEHLKRILENMQFQNEELAYLIKKEDESLQCSKLQLEEKIAEYNSLTKQLESALEEGRKMVAEEFEKMSYLEQALQTKMLVLENEVRERQEEKKELLCAFHRNEKHHEVCLKELENSLQRSENKKQSIQNYVQFLKTSYITMFG", "length": 716, "header": "tr|A0A8V0ZZ76-1|A0A8V0ZRQ9_CHICK Computationally mapped isoform of Outer dense fiber of sperm tails 2 like OS=Gallus gallus OX=9031 GN=ODF2L PE=3 SV=1 CANONICAL=A0A8V0ZRQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15739211, "end_pos": 15721056, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056461.1", "url": "https://www.ensembl.org/id/ENSGALT00010056461.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034204.1", "url": "https://www.ensembl.org/id/ENSGALP00010034204.1" } ] } }, { "isoform_ac": "A0A8V0ZZ92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9/entry#A0A8V0ZZ92-1", "sequence": { "sequence": "MWGPRPDKHGIKITELFPLLKGGSPKNHLPQNLNGSVERRCASDKERREEENASHENGASQEIFEAEMAINSAENLLPTFKDILGRMTNQVCKPSTSEMIIIDTQEDLLVKELTTLKTTKRLLWLLLQTREQKQIDSKNIEALIQKLSENETHNMSLRRKIVEREEHVKELSSRIQLKKVPVLKEEYLSRPVNTIEAHLQYQIQRKEVENDELRLKTQTLEKKIAEWKLQIGEYKRQMLALKKTSEQKKAYLRRAIRSQKQKTECFEEAVENLTSRVKEREVKLSEILSASDVWKKQHDRMVEEKTMLAVQTEDLKKQITSLSEDLKRKEEFRRKASEELLGKLNSVNSENEKIYLENEKLKACLAALEISTVSVENDLLCLQEKTKLQENIVEDCKNQVRELKAEVEVLKSRYKIIFSENKSIRESKCLEVYEVRDKAEPKLKVLEHVCGLLKAAEGELRGFQENLVYWERINTQKCKTPRELQVQEEDGVNSVGNCSLEEENSTIQKKYEHLKRILENMQFQNEELAYLIKKEDESLQCSKLQLEEKIAEYNSLTKQLESALEEGRKMVAEEFEKMSYLEQALQTKMLVLENEVRERQEEKKELLCAFHRNEKHHEVCLKELENSLQRPAWMPTRVTCCREPALGGELDSMISRGLFQLLQFRDSVIYPFMLTQLH", "length": 678, "header": "tr|A0A8V0ZZ92-1|A0A8V0ZRQ9_CHICK Computationally mapped isoform of Outer dense fiber of sperm tails 2 like OS=Gallus gallus OX=9031 GN=ODF2L PE=3 SV=1 CANONICAL=A0A8V0ZRQ9-1" }, "locus": { "chromosome": "8", "start_pos": 15740093, "end_pos": 15722975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056477.1", "url": "https://www.ensembl.org/id/ENSGALT00010056477.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034220.1", "url": "https://www.ensembl.org/id/ENSGALP00010034220.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of cilium assembly", "id": "GO:1902018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 154, "end_pos": 156 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 444, "end_pos": 446 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRM0-1", "uniprot_ac": "A0A8V0ZRM0", "uniprot_id": "A0A8V0ZRM0_CHICK", "mass": { "chemical_mass": 131297.0, "monoisotopic_mass": 131297.0 }, "refseq": { "ac": "XP_040559112", "name": "cell division cycle and apoptosis regulator protein 1 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559112" }, "gene_names": [ { "name": "CCAR1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ] }, { "name": "CCAR1", "type": "synonym", "evidence": [ { "id": "XP_040559112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559112" } ] } ], "protein_names": [ { "name": "Cell division cycle and apoptosis regulator protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0/entry#names_and_taxonomy" } ] }, { "name": "Cell cycle and apoptosis regulatory protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0/entry#names_and_taxonomy" } ] }, { "name": "cell division cycle and apoptosis regulator protein 1 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_040559112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559112" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040559112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559112" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0", "locus": { "chromosome": "6", "start_pos": 11515629, "end_pos": 11489673, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023140", "url": "https://www.ensembl.org/id/ENSGALG00010023140" } ] } } ], "crossref": [ { "id": "A0A8V0ZRM0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "423692", "url": "https://www.ncbi.nlm.nih.gov/gene/423692", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MVEASYN", "url": "https://omabrowser.org/oma/group/MVEASYN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLA6", "url": "https://www.orthodb.org/?gene=A0A8V0ZLA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRM0", "url": "https://www.orthodb.org/?gene=A0A8V0ZRM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTK7", "url": "https://www.orthodb.org/?gene=A0A8V0ZTK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUM3", "url": "https://www.orthodb.org/?gene=A0A8V0ZUM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14304:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14304:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14444", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14444", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040559112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040559112", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPTNYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQPAVALPTSLSLSTPQPAAQITVSYPAPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQTQAQPLLKTPPAVLQPIAQQTAFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKGGLLQPPVRLVSQPQPARRLDPPSRFSGRNDRGGDPMPNRKDDRSRERDRERRRSRERSPQRKRSRERSPRRERERSPRRPRRVVPRYTVQFSKFSLDCRSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPMSRPFQLGNYCNFYVMHREVDPIDKNAAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEEEEEDRKSEDDKEEEERKRQEEMERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKALISLPEREDKKDKKSKKDERKEKKEEKEEENDEPKPKRRKSGDDKEKKEDKDEKKREEKRKDDSKDEEETEDDNNQEEYDPMEAEEAEDEDEDREEEEMNKREDRREGNKHCKERSSKDKEKDKTQMITVNRDLLMAFVYFDQSHCGYLLEKDMEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRRLTDTSKDEENQEESEELQEDMLGNRLLLPSPTVKQESKAVEENVGLIVYNGAMVDVGSLLQKLEKSERVRAEIEQKLQLLEEKTDEDEKTILQLENSNKSLSAELRDVKKDLSQLQENLKISDEKNLQFESQLNKTIKNLATVMDEMQSVLKQDIVKSEDKDQKSKENGASV", "length": 1138, "header": "tr|A0A8V0ZRM0-1|A0A8V0ZRM0_CHICK Isoform 1 of Cell division cycle and apoptosis regulator protein 1 OS=Gallus gallus OX=9031 GN=CCAR1 PE=1 SV=1 CANONICAL=A0A8V0ZRM0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0/entry#A0A8V0ZLA6-1", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPTNYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQLQQPQQTILTQPAVALPTSLSLSTPQPAAQITVSYPAPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQTQAQPLLKTPPAVLQPIAQQTAFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKGGLLQPPVRLVSQPQPARRLDPPSRFSGRNDRGGDPMPNRKDDRSRERDRERRRSRERSPQRKRSRERSPRRERERSPRRPRRVVPRYTVQFSKFSLDCRSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPMSRPFQLGNYCNFYVMHREVDPIDKNAAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWMKRKRMMGKQKRSLHLHTGLNWIRKQ", "length": 569, "header": "tr|A0A8V0ZLA6-1|A0A8V0ZRM0_CHICK Computationally mapped isoform of Cell division cycle and apoptosis regulator protein 1 OS=Gallus gallus OX=9031 GN=CCAR1 PE=1 SV=1 CANONICAL=A0A8V0ZRM0-1" }, "locus": { "chromosome": "6", "start_pos": 11505135, "end_pos": 11490375, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056399.1", "url": "https://www.ensembl.org/id/ENSGALT00010056399.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034150.1", "url": "https://www.ensembl.org/id/ENSGALP00010034150.1" } ] } }, { "isoform_ac": "A0A8V0ZRM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0/entry#A0A8V0ZRM0-1", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPTNYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQPAVALPTSLSLSTPQPAAQITVSYPAPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQTQAQPLLKTPPAVLQPIAQQTAFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKGGLLQPPVRLVSQPQPARRLDPPSRFSGRNDRGGDPMPNRKDDRSRERDRERRRSRERSPQRKRSRERSPRRERERSPRRPRRVVPRYTVQFSKFSLDCRSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPMSRPFQLGNYCNFYVMHREVDPIDKNAAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEEEEEDRKSEDDKEEEERKRQEEMERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKALISLPEREDKKDKKSKKDERKEKKEEKEEENDEPKPKRRKSGDDKEKKEDKDEKKREEKRKDDSKDEEETEDDNNQEEYDPMEAEEAEDEDEDREEEEMNKREDRREGNKHCKERSSKDKEKDKTQMITVNRDLLMAFVYFDQSHCGYLLEKDMEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRRLTDTSKDEENQEESEELQEDMLGNRLLLPSPTVKQESKAVEENVGLIVYNGAMVDVGSLLQKLEKSERVRAEIEQKLQLLEEKTDEDEKTILQLENSNKSLSAELRDVKKDLSQLQENLKISDEKNLQFESQLNKTIKNLATVMDEMQSVLKQDIVKSEDKDQKSKENGASV", "length": 1138, "header": "tr|A0A8V0ZRM0-1|A0A8V0ZRM0_CHICK Isoform 1 of Cell division cycle and apoptosis regulator protein 1 OS=Gallus gallus OX=9031 GN=CCAR1 PE=1 SV=1 CANONICAL=A0A8V0ZRM0-1" }, "locus": { "chromosome": "6", "start_pos": 11514772, "end_pos": 11490375, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056417.1", "url": "https://www.ensembl.org/id/ENSGALT00010056417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034163.1", "url": "https://www.ensembl.org/id/ENSGALP00010034163.1" } ] } }, { "isoform_ac": "A0A8V0ZTK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0/entry#A0A8V0ZTK7-1", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPTNYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQLQQPQQTILTQPAVALPTSLSLSTPQPAAQITVSYPAPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQTQAQPLLKTPPAVLQPIAQQTAFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKGGLLQPPVRLVSQPQPARRLDPPSRFSGRNDRGGDPMPNRKDDRSRERDRERRRSRERSPQRKRSRERSPRRERERSPRRPRRVVPRYTVQFSKFSLDCRSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPMSRPFQLGNYCNFYVMHREVDPIDKNAAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEEEEEDRKSEDDKEEEERKRQEEMERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKALISLPEREDKKDKKSKKDERKEKKEEKEEENDEPKPKRRKSGDDKEKKEDKDEKKREEKRKDDSKDEEETEDDNNQEEYDPMEAEEAEDEDEECRPLATPIEVSRRYREEEEMNKREDRREGNKHCKERSSKDKEKDKTQMITVNRDLLMAFVYFDQSHCGYLLEKDMEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRRLTDTSKDEENQEESEELQEDMLGNRLLLPSPTVKQESKAVEENVGLIVYNGAMVDVGSLLQKLEKSERVRAEIEQKLQLLEEKTDEDEKTILQLENSNKSLSAELRDVKKDLSQLQENLKISDEKNLQFESQLNKTIKNLATVMDEMQSVLKQDIVKSEDKDQKSKENGASV", "length": 1163, "header": "tr|A0A8V0ZTK7-1|A0A8V0ZRM0_CHICK Computationally mapped isoform of Cell division cycle and apoptosis regulator protein 1 OS=Gallus gallus OX=9031 GN=CCAR1 PE=1 SV=1 CANONICAL=A0A8V0ZRM0-1" }, "locus": { "chromosome": "6", "start_pos": 11514772, "end_pos": 11490375, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056405.1", "url": "https://www.ensembl.org/id/ENSGALT00010056405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034154.1", "url": "https://www.ensembl.org/id/ENSGALP00010034154.1" } ] } }, { "isoform_ac": "A0A8V0ZUM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0/entry#A0A8V0ZUM3-1", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPTNYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQPAVALPTSLSLSTPQPAAQITVSYPAPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQTQAQPLLKTPPAVLQPIAQQTAFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKGGLLQPPVRLVSQPQPARRLDPPSRFSGRNDRGGDPMPNRKDDRSRERDRERRRSRERSPQRKRSRERSPRRERERSPRRPRRVVPRYTVQFSKFSLDCRSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPMSRPFQLGNYCNFYVMHREVDPIDKNAAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEEEEEDRKSEDDKEEEERKRQEEMERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKALISLPEREDKKDKKSKKDERKEKKEEKEEENDEPKPKRRKSGDDKEKKEDKDEKKREEKRKDDSKDEEETEDDNNQEEYDPMEAEEAEDEDEECRPLATPIEVSRRYREEEEMNKREDRREGNKHCKERSSKDKEKDKTQMITVNRDLLMAFVYFDQSHCGYLLEKDMEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRRLTDTSKDEENQEESEELQEDMLGNRLLLPSPTVKQESKAVEENVGLIVYNGAMVDVGSLLQKLEKSERVRAEIEQKLQLLEEKTDEDEKTILQLENSNKSLSAELRDVKKDLSQLQENLKISDEKNLQFESQLNKTIKNLATVMDEMQSVLKQDIVKSEDKDQKSKENGASV", "length": 1152, "header": "tr|A0A8V0ZUM3-1|A0A8V0ZRM0_CHICK Computationally mapped isoform of Cell division cycle and apoptosis regulator protein 1 OS=Gallus gallus OX=9031 GN=CCAR1 PE=1 SV=1 CANONICAL=A0A8V0ZRM0-1" }, "locus": { "chromosome": "6", "start_pos": 11514772, "end_pos": 11490375, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056411.1", "url": "https://www.ensembl.org/id/ENSGALT00010056411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034158.1", "url": "https://www.ensembl.org/id/ENSGALP00010034158.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZYY3-1", "protein_name": "Cell division cycle and apoptosis regulator protein 1", "gene_name": "CCAR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQQYSQPQQTLYSVQQQLQQPQQTLLTQPAVGLPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNERGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNIAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRTLSSKGLKSQLIARLTKQLKLEEQKEEQKELEKSEKEEEEEDDRKSEDDKEEEERKRQEELERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKEKKSKKDDRKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEINKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESEALQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKNLSGELREVKKDLSQLQENLKTSENMNLQFENQLNKTIRNLSTVMDEIHTVLKQDNVKNEDKDQKSKENGASV", "length": 1150 }, "evidence": [ { "id": "A0A8V0ZRM0", "url": "https://omabrowser.org/oma/group/A0A8V0ZRM0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A183-1", "protein_name": "Cell division cycle and apoptosis regulator protein 1", "gene_name": "Ccar1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAVLQQQYSQPQQALYSVQQQPAVALPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLGAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPTAVIQPIVPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERDRERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNVAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQDLRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPNPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKKADGEQDEEEKDDGEVKEIATPTHWSKLDPKAMKVNDLRKELESRALSSKGLKSQLIARLTKQLKIEEQKEEQKELEKSEKEEEDEDDKKSEDDKEEEERKRQEEVERQRQERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKDKEKKSKKEERKDKKEEREDDIDEPKPKRRKSGDDKDKKEDRDERKKEEKRKDDSKDDDETEEDNNQDEYDPMEAEEAEEEEDDREEEEVNKRDDKRDVSRYCKDRPSKDKEKEKPQMVTVNRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDGESHDEPESLQGDTTLGNRLLLPTPTVKQESKDGEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDGKTILNLENSNKSLSGELREVKKDLGQLQENLKVSENMNLQFENQLNKTLRNLSTVMDDIHTVLKKDNVKNEDRDQKSKENGSSV", "length": 1137 }, "evidence": [ { "id": "A0A8V0ZRM0", "url": "https://omabrowser.org/oma/group/A0A8V0ZRM0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2B3E5-1", "protein_name": "Cell division cycle and apoptosis regulator protein 1", "gene_name": "ccar1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQFGGQKNPPWAAQFAATAVSQPGHTGQSLDLNSLHSLGVQQQSLLGASPMYTQQSALAAASLNSQSAANYQLSQQTAALQQQAAAAAAAAALQQSQINSALQQYQQQQQQQQQPPQAPPPQPPPQQTLYNVPHQLPQPQQALLSQPPVALPTSLSLSNPQQTAQITVSYPTPRSSHQQQTQPQKQRVFTGVVSKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEAVYNPNMPFKWNAQRIQTLPQLPNQTHQPPQPLPQVSPQLSSFYTDAGMQRYSDLHSAVDSRQNSQPQVPNMMKPGPTMLQSLPPPTTFSVPAQGPPPSLLQAQLSAASLAPLLQNPPQPLLPQPPPKDSVFSGGLLQPPVRMMPQPQQVRRVEPSPRFPNRSDRPELILRKDDRRSALKHTPDSQCFSRRSRERERERRRSRERSPMRKRSRDRSPRRERSPRRPRRVVPRYTVQFSKFSLDGYNCDMMELRRRYQSLYIPSDFFNAVFTWVDAFPLSRPFTFGNYCNFHIMHKEVDSLVKNTAVLDPPDANHTYSAKVMLLANPSLDELYHKSCALSEDPAELRDSFQHPARLIKFLVGMRGKDEAMAIGGHWSPSLDGADPEHDASVLIKTAVRCCKALTGIDLSLCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFLPDVWHCLPTRSEWEELSRGLKEQLAEKLLAERKEADGEQEEEDKDEDDSKEVTTPTHWSKLDPKSMKVSDLRKELESRSLSSKGLKSQLIARLTKQLKVEEQVEESKEPEKPEPPSVEEDESCRLEDDREEEERKRQEEQERQRRERRYVLPDEPTIIVHPNWAAKNGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGYRIYKALASLPTKDEKKDKKERAKKEAERRDIKKERDEDNGEPVTKRIREEDDKRKDEEKERGIKREESKDDDDNEDGSSNNNADEYDPLEAEDADDYDDDDKDDEDSNGRDRRDDRRDDRKSKDRSSKDKDEKKRQMVTFNKDLLMAFVYFDQSHCGYLLEKDLEEIMYTLGLHLSRAQVKKLLNKPLVKESCHYRKLTDRPKDEPCPALISEAHIDNLLGNQILLTSQKIKREPDESGESGSLIVYKGALVDVGSMMQKLEKSEKTREDIEQKLMQQDVKMEEDSKHISELEAANRSLQKELDDVKNTLRETESKLTASDQRKGRFEQQLHSTVSSLDTIKKELQGVLANNDRSEDADHKTQANGSDE", "length": 1254 }, "evidence": [ { "id": "A0A8V0ZRM0", "url": "https://omabrowser.org/oma/group/A0A8V0ZRM0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8CH18-1", "protein_name": "Cell division cycle and apoptosis regulator protein 1", "gene_name": "Ccar1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAVLQQQYSQPQQALYSVQQQLQQPQQTILTQPAVALPTSLSLSTPQPAAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLGAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPTAVIQPIVPQTTFGVQAQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERDRERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAVLDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQDLRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPNPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKKADGEQDEEEKDDGEVKEIATPTHWSKLDPKAMKVNDLRKELESRALSSKGLKSQLIARLTKQLKIEEQKEEQKELEKSEKEEEDEDDKKSEDDKEEEERKRQEEVERQRQERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKDKEKKSKKEERKDKKEEREDDIDEPKPKRRKSGDDKDKKEDRDERKKEEKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEDDDREEEEVKRDDKRDVSRYCKDRPAKDKEKEKPQMVTVNRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDDENHEESEALQEDMLGNRLLLPTPTIKQESKDGEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDGKTILNLENSNKSLSGELREVKKDLGQLQENLEVSENMNLQFENQLNKTLRNLSTVMDDIHTVLKKDNVKSEDRDEKSKENGSGV", "length": 1146 }, "evidence": [ { "id": "A0A8V0ZRM0", "url": "https://omabrowser.org/oma/group/A0A8V0ZRM0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IX12-1", "protein_name": "Cell division cycle and apoptosis regulator protein 1", "gene_name": "CCAR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQQYSQPQQALYSVQQQLQQPQQTLLTQPAVALPTSLSLSTPQPTAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQTQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAILDPPDADHLYSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVEENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKKDNVKNEDKDQKSKENGASV", "length": 1150 }, "evidence": [ { "id": "A0A8V0ZRM0", "url": "https://omabrowser.org/oma/group/A0A8V0ZRM0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "nuclear envelope lumen", "id": "GO:0005641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005641", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1064, "end_pos": 1066, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1100, "end_pos": 1102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM0" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 626, "end_pos": 660, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1064, "end_pos": 1066 }, { "start_pos": 1100, "end_pos": 1102 }, { "start_pos": 201, "end_pos": 203 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZP43-1", "uniprot_ac": "A0A8V0ZP43", "uniprot_id": "A0A8V0ZP43_CHICK", "mass": { "chemical_mass": 16815.0, "monoisotopic_mass": 16815.0 }, "refseq": {}, "gene_names": [ { "name": "MANBAL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP43" } ] } ], "protein_names": [ { "name": "Mannosidase beta like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZP43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP43/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP43" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MANBAL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP43", "locus": { "chromosome": "20", "start_pos": 5404362, "end_pos": 5398956, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022593", "url": "https://www.ensembl.org/id/ENSGALG00010022593" } ] } } ], "crossref": [ { "id": "A0A8V0ZP43", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP43", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038797", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038797", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428138", "url": "https://www.ncbi.nlm.nih.gov/gene/428138", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428138", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428138", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KSYEVET", "url": "https://omabrowser.org/oma/group/KSYEVET/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5NZB7", "url": "https://www.orthodb.org/?gene=A0A1D5NZB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP43", "url": "https://www.orthodb.org/?gene=A0A8V0ZP43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14409:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14409:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06783", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06783", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5NZB7", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5NZB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NZB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSLNEGVRGKQRPGEEWSEPPGCCVGPRVWPWMKVGFLRALLLRLALCIHKKAASLRAAEQQAVRAMAAEVHFSPPEIPEPTLLENVLRYGLFFGAIFQLLCVLAIILPVSKSPEADSVGSESKTLEAVKKPKASSAAQLSKKAKKEGKKRR", "length": 153, "header": "tr|A0A8V0ZP43-1|A0A8V0ZP43_CHICK Isoform 1 of Mannosidase beta like OS=Gallus gallus OX=9031 GN=MANBAL PE=3 SV=1 CANONICAL=A0A8V0ZP43-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NZB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP43/entry#A0A1D5NZB7-1", "sequence": { "sequence": "MAAEVHFSPPEIPEPTLLENVLRYGLFFGAIFQLLCVLAIILPVSKSPEADSVGSESKTLEAVKKPKASSAAQLSKKAKKEGKKRR", "length": 86, "header": "tr|A0A1D5NZB7-1|A0A8V0ZP43_CHICK Computationally mapped isoform of Mannosidase beta like OS=Gallus gallus OX=9031 GN=MANBAL PE=3 SV=2 CANONICAL=A0A8V0ZP43-1" }, "locus": { "chromosome": "20", "start_pos": 5403086, "end_pos": 5401514, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054981.1", "url": "https://www.ensembl.org/id/ENSGALT00010054981.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033245.1", "url": "https://www.ensembl.org/id/ENSGALP00010033245.1" } ] } }, { "isoform_ac": "A0A8V0ZP43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP43/entry#A0A8V0ZP43-1", "sequence": { "sequence": "MRSLNEGVRGKQRPGEEWSEPPGCCVGPRVWPWMKVGFLRALLLRLALCIHKKAASLRAAEQQAVRAMAAEVHFSPPEIPEPTLLENVLRYGLFFGAIFQLLCVLAIILPVSKSPEADSVGSESKTLEAVKKPKASSAAQLSKKAKKEGKKRR", "length": 153, "header": "tr|A0A8V0ZP43-1|A0A8V0ZP43_CHICK Isoform 1 of Mannosidase beta like OS=Gallus gallus OX=9031 GN=MANBAL PE=3 SV=1 CANONICAL=A0A8V0ZP43-1" }, "locus": { "chromosome": "20", "start_pos": 5403086, "end_pos": 5398976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054986.1", "url": "https://www.ensembl.org/id/ENSGALT00010054986.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033248.1", "url": "https://www.ensembl.org/id/ENSGALP00010033248.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428138", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428138", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3L5E1-1", "protein_name": "Mannosidase beta like", "gene_name": "MANBAL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASDLDFSPPEVPEPTFLENLLRYGLFLGAIFQLICVLAIIVPVPKSHETEAEPSEPRSTEVTRKPKATAPSANKRPKKEAKKKR", "length": 85 }, "evidence": [ { "id": "A0A8V0ZP43", "url": "https://omabrowser.org/oma/group/A0A8V0ZP43/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5BJY8-1", "protein_name": "Mannosidase beta like", "gene_name": "Manbal", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASDLDFSPPEVPEPTFLENLLRYGLFLGAIFQLICVLAIIVPIPKSQEAEAEPSEPRSAEVPKKPKAPIPSTNKRPKKETKKKR", "length": 85 }, "evidence": [ { "id": "A0A8V0ZP43", "url": "https://omabrowser.org/oma/group/A0A8V0ZP43/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D8X0-1", "protein_name": "Protein MANBAL", "gene_name": "Manbal", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASDLGFSPPEVPEPTFLENLLRYGLFLGAIFQLICVLAIIVPIPKSHEAEAEQAEPRSAEGPKKPKAAIASTNKRPKKETKKKR", "length": 85 }, "evidence": [ { "id": "A0A8V0ZP43", "url": "https://omabrowser.org/oma/group/A0A8V0ZP43/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQG1-1", "protein_name": "Protein MANBAL", "gene_name": "MANBAL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASDLDFSPPEVPEPTFLENLLRYGLFLGAIFQLICVLAIIVPIPKSHEAEAEPSEPRSAEVTRKPKAAVPSVNKRPKKETKKKR", "length": 85 }, "evidence": [ { "id": "A0A8V0ZP43", "url": "https://omabrowser.org/oma/group/A0A8V0ZP43/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRB7-1", "uniprot_ac": "A0A8V0ZRB7", "uniprot_id": "A0A8V0ZRB7_CHICK", "mass": { "chemical_mass": 88519.0, "monoisotopic_mass": 88519.0 }, "refseq": { "ac": "NP_001025528", "name": "proprotein convertase subtilisin/kexin type 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025528" }, "gene_names": [ { "name": "PCSK7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7" } ] }, { "name": "PC7", "type": "synonym", "evidence": [ { "id": "NP_001025528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025528" } ] }, { "name": "PCSK7", "type": "synonym", "evidence": [ { "id": "NP_001025528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025528" } ] } ], "protein_names": [ { "name": "Proprotein convertase subtilisin/kexin type 7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7/entry#names_and_taxonomy" } ] }, { "name": "Prohormone convertase 7", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7/entry#names_and_taxonomy" } ] }, { "name": "Proprotein convertase 7", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7/entry#names_and_taxonomy" } ] }, { "name": "Subtilisin/kexin-like protease PC7", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7/entry#names_and_taxonomy" } ] }, { "name": "proprotein convertase PC7", "type": "synonym", "evidence": [ { "id": "NP_001025528", "database": "RefSeq", "url": 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The reference sequence was derived from JAENSK010000341.1. On Sep 23, 2021 this sequence version replaced NP_001025528.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001025528", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025528" } ] }, { "annotation": "Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive secretory pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P0B8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0B8#function" }, { "database": "UniProtKB", "id": "ARBA00054142", "url": "https://www.uniprot.org/uniprotkb/ARBA00054142#function" }, { "database": "UniProtKB", "id": "A0A8V0ZRB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PCSK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7", "locus": { "chromosome": "24", "start_pos": 5265632, "end_pos": 5281544, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023086", "url": "https://www.ensembl.org/id/ENSGALG00010023086" } ] } } ], "crossref": [ { "id": "A0A8V0ZRB7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000029220", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000029220", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395455", "url": "https://www.ncbi.nlm.nih.gov/gene/395455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000209", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000209", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42884:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00082", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00082", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01483", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01483", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9768727", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9768727", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001025528", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025528", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P0B8", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P0B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPHRERRLRRWSAGAQAVRCVHTCLWLGAAWIPSVLSHGLTRGTELDDGRAVAHGPGELAWAVSLDVPEEQVEQRAEQLARTAGLVNMGRIGELKGHYLFSYRPDSHAAPEPEAIRRSVDTLFAQHDSVRWHSEQKLLKRSKRSLHFNDPKYPQQWHLNNRKSPGKDINVTGVWERNVTGRGVTVVVVDDGVEHTIKDIQPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCTVGVAYGSRIAGIRVLDGPLTDSMEAIAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRRGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEMGSMPFYAEECASMLAVTFSGGDKMMRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATKYEDRHAKWDVNRAGFSHSHQHGFGLLNAWRLVNAAKIWESVPYLASYVSPVLKEGRSIPLLPQELEATWNVTTTDLQLSGMRTLEHVAVTVTITHPRRGNLEIRLFCPSGMMSLIGTTRSMDSDPNGFADWTFSTVRCWGEEAQGTYRLVIRDTGDQSLRPGTLKQWQLTLYGSSWSPAEMKERQRLLEEAMSGQYLNNDFSLPCPPGLEIPEQQHYTITANTLKTLLLLGCFAVFWTFYYMLEVCLSRNNVGLDLTCHGSTACRWYQQGGKHRALENGLEMESVPLYREKEVEDIEVECELLEPVQEDTGEEGSWTPTLPKLPASSRAAAPTTAGYLGREAAAELLADDRELQTC", "length": 799, "header": "tr|A0A8V0ZRB7-1|A0A8V0ZRB7_CHICK Isoform 1 of Proprotein convertase subtilisin/kexin type 7 OS=Gallus gallus OX=9031 GN=PCSK7 PE=3 SV=1 CANONICAL=A0A8V0ZRB7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P0B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7/entry#A0A1D5P0B8-1", "sequence": { "sequence": "MPHRERRLRRWSAGAQAVRCVHTCLWLGAAWIPSVLSHGLTRGTELDDGRAVAHGPGELAWAVSLDVPEEQVEQRAEQLARTAGLVNMGRIGELKGHYLFSYRPDSHAAPEPEAIRRSVDTLFAQHDSVRWHSEQKLLKRSKRSLHFNDPKYPQQWHLNNRKSPGKDINVTGVWERNVTGRGVTVVVVDDGVEHTIKDIQPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCTVGVAYGSRIAGIRVLDGPLTDSMEAIAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRRGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEMGSMPFYAEECASMLAVTFSGGDKMMRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATKYEDRHAKWDVNRAGFSHSHQHGFGLLNAWRLVNAAKIWESVPYLASYVSPVLKEGRSIPLLPQELEATWNVTTTDLQLSGMRTLEHVAVTVTITHPRRGNLEIRLFCPSGMMSLIGTTRSMDSDPNGFADWTFSTVRCWGEEAQGTYRLVIRDTGDQSLRPGTLKQWQLTLYGSSWSPAEMKERQR", "length": 629, "header": "tr|A0A1D5P0B8-1|A0A8V0ZRB7_CHICK Computationally mapped isoform of Proprotein convertase subtilisin/kexin type 7 OS=Gallus gallus OX=9031 GN=PCSK7 PE=3 SV=1 CANONICAL=A0A8V0ZRB7-1" }, "locus": { "chromosome": "24", "start_pos": 5280954, "end_pos": 5267386, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056244.1", "url": "https://www.ensembl.org/id/ENSGALT00010056244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034044.1", "url": "https://www.ensembl.org/id/ENSGALP00010034044.1" } ] } }, { "isoform_ac": "A0A8V0ZRB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7/entry#A0A8V0ZRB7-1", "sequence": { "sequence": "MPHRERRLRRWSAGAQAVRCVHTCLWLGAAWIPSVLSHGLTRGTELDDGRAVAHGPGELAWAVSLDVPEEQVEQRAEQLARTAGLVNMGRIGELKGHYLFSYRPDSHAAPEPEAIRRSVDTLFAQHDSVRWHSEQKLLKRSKRSLHFNDPKYPQQWHLNNRKSPGKDINVTGVWERNVTGRGVTVVVVDDGVEHTIKDIQPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCTVGVAYGSRIAGIRVLDGPLTDSMEAIAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRRGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEMGSMPFYAEECASMLAVTFSGGDKMMRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATKYEDRHAKWDVNRAGFSHSHQHGFGLLNAWRLVNAAKIWESVPYLASYVSPVLKEGRSIPLLPQELEATWNVTTTDLQLSGMRTLEHVAVTVTITHPRRGNLEIRLFCPSGMMSLIGTTRSMDSDPNGFADWTFSTVRCWGEEAQGTYRLVIRDTGDQSLRPGTLKQWQLTLYGSSWSPAEMKERQRLLEEAMSGQYLNNDFSLPCPPGLEIPEQQHYTITANTLKTLLLLGCFAVFWTFYYMLEVCLSRNNVGLDLTCHGSTACRWYQQGGKHRALENGLEMESVPLYREKEVEDIEVECELLEPVQEDTGEEGSWTPTLPKLPASSRAAAPTTAGYLGREAAAELLADDRELQTC", "length": 799, "header": "tr|A0A8V0ZRB7-1|A0A8V0ZRB7_CHICK Isoform 1 of Proprotein convertase subtilisin/kexin type 7 OS=Gallus gallus OX=9031 GN=PCSK7 PE=3 SV=1 CANONICAL=A0A8V0ZRB7-1" }, "locus": { "chromosome": "24", "start_pos": 5280954, "end_pos": 5266362, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056252.1", "url": "https://www.ensembl.org/id/ENSGALT00010056252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034051.1", "url": "https://www.ensembl.org/id/ENSGALP00010034051.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 533, "start_aa": "Thr", "end_pos": 533, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr533", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:395455", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395455", "resource": "KEGG Pathway" }, { "id": "R-GGA-9768727", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9768727", "resource": "Reactome", "description": "Regulation of CDH1 posttranslational processing and trafficking to plasma membrane" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SX84-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "PCSK7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPKGRQKVPHSDAPLGLPARLWLELAGLFLLLPWVMGLVGAGGPGAQGPGGLSWAVHLDHPEGEGEADLLEQQADALAQAAGLVNAGRIGELQGHYLLVQPAGHPQPQQAEAVRQQVEAVLARHEAVRWHSEQRLLKRAKRSIHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATQYEDRHADWITNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKEDKAIPLSARPLEVLWNVSRTDLEMSGLKTLEHVAVTVSITHPRRGSLEVKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDEKSQAGILRQWQLTLYGSVWSPVDIRDRQRLLESAMSGKYLHDGFTLPCPPGLKIPEEDGYTITPNTLKTLVLIGCFTVFWTIYYMLEVYLSQRNVASHPVCRSGPCHWPQQSRKAKEEGTELEAVPLCSSQDPGGVGTESEGPSAPSRLRAPDLLDQGDWSLSQNRGALDCPQRLPPDLLQGKGEQIC", "length": 786 }, "evidence": [ { "id": "A0A8V0ZRB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M1P8P5-1", "protein_name": "3.4.21.-", "gene_name": "pcsk7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASCSSRVCLGLYPLLLLFSSSSSSCAPGRSWAVQLQPDSLSSAGSPDLLAQAVAQDVGLRSHGQIGQLEGHYLLCQDPAQGEDWRWMEAALDRHPHVAWHSQENVLRRSKRSVHFNDPKFPSQWHLHNDMKRGMDINVTGVWERNITGAGVTVVVVDDGIQHNLADIQPNYSPEGSYDLNSNDPDPMPHPDGPSDNHHGTRCAGEIAAVSNNSFCAVGVAYGSRVAGIRVLDGPLTDSMEAIAFNKHYQVNDIYSCSWGPDDDGRTVDGPHPLGKAALQHGVIAGRKGFGSIFIVASGNGGQNQDNCNYDGYANSIYTVTIGAVDESGRKPTYAEECASMLAVTFSSGNTPLRSIVTSDWSLQSGTGCTSGHTGTSAAAPLAAGMVALMLQVRPCLSWRDVQHIITYTATQHDLQADWVTNGAGFHHSHKYGFGLLNAWRLVNAAKVWESVPFLVSYQSPVLRVNEVITTSTNLTQTWNVSESDLQRSGMQTLEHVSVTLSIQHPRRGNLQILLLCPSGISSLIGARRALDVDSAGLTDWTFSTVRCWGEQAEGQYSLLIMDDAPLSSGILKSWKLTLYGSSLSHQQVTDRQRVVEEAMSGHYLSSSFSLPCPPGIDVPAEIVNPFTSSSLKSLLLLGCFTLFWSLYYTLEVVLTHWDWRGGCVRGRDGDAGYSRLSRDEAQTDPQQVEVLLETHSQDKVLLIADTHT", "length": 709 }, "evidence": [ { "id": "A0A8V0ZRB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BEJ2-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "PCSK7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKGRQKVPHSDAPLGLPTGLWLELAGLFLLLPWVMGLVGAGGPRAQGPRGLSWAVRLDGPEGEGAEESLERRADALAQATGLMNAGRIGELQGHYLLVQPAGHRQARQVKAIRQQVEAVLARHEAVRWHSEQRLLKRTKRGVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDLENGNHHGTRCAGEIAAVPNNSFCAVGVAFGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATRYEDRHADWITNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKENKAIPLSARPLEVLWNVSRMDLDMSGLKTLEHVAVTISITHPRRGSLEVKLFCPSGMMSLIGAPRSLDSDPNGFNDWTFSTVRCWGERAKGTYRLVIRDVGDETSQAGVLRQWQLTLYGSVWSPVDIRDRQRLLESAMSGKYLHDGFTLPCPPGLNIPEEDGYTITPNTLKTLVLIGCFTVFWTIYYTLEVYLSQRNVAFGPICRSGPCHWPQRSQKAKEEGTELESMPLCSSQDPGGVGLESEGSPTTSRLHAPDLLDQGDWSLSQSRGALDVPQLLPPDLLQGKEAQMC", "length": 786 }, "evidence": [ { "id": "A0A8V0ZRB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3IAK2-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "Pcsk7", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPKGRQKVPHLDAPLGLPICLWLELAGLLFMVPWVMGLSEASGLDSLGAGGLSWAVHLDSLEGERKEESLMQQADALAQAAGLVNAGRIGELQGHYLLVQPAGHKQAMEVEAMRQQAEAVLAQHEAVRWHSEQKLLKRAKRSIHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDAENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDIQHIIVFTATQYEDHHADWLTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKENKAVPRSPNSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLAIRDVGDEPLQVGILRQWQLTLYGSMWSPVDIKDRQSLLESAMSGKYLHDGFTLPCPPGLKIPEEDGYTITPNTLKTLVLVGCFTVFWTIYYMLEIYLSQRNMASTQGCRSGHCPWPQRSQNSREVGTELESVPLCNSKDQDGVDSENGSCTATSTFLTPELLRERDWNLSQSSKSILDCPQHQPPDLLQGKDGQIC", "length": 787 }, "evidence": [ { "id": "A0A8V0ZRB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q16549-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "PCSK7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKGRQKVPHLDAPLGLPTCLWLELAGLFLLVPWVMGLAGTGGPDGQGTGGPSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEAIRQQVEAVLAGHEAVRWHSEQRLLRRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATRYEDRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKENKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDESFQVGILRQWQLTLYGSVWSAVDIRDRQRLLESAMSGKYLHDDFALPCPPGLKIPEEDGYTITPNTLKTLVLVGCFTVFWTVYYMLEVYLSQRNVASNQVCRSGPCHWPHRSRKAKEEGTELESVPLCSSKDPDEVETESRGPPTTSDLLAPDLLEQGDWSLSQNKSALDCPHQHLDVPHGKEEQIC", "length": 785 }, "evidence": [ { "id": "A0A8V0ZRB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61139-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "Pcsk7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKGRQKVPHLDAHLGLPICLWLELAIFFLVPQVMGLSEAGGLDILGTGGLSWAVHLDSLEGERKEESLTQQADAVAQAAGLVNAGRIGELQGHYLFVQPTGHRQAMEVEAMRQQAEAVLARHEAVRWHSEQTLLKRAKRSIHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTVQDIAPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVMAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTAIQYEDHHADWLTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPMLKENKAVPRSPHSLEVLWNVSRTDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNAWTFSTVRCWGERARGVYRLVIRDVGDEPLQMGILQQWQLTLYGSMWSPVDIKDRQSLLESAMSGKYLHDGFTLPCPPGLKIPEEDGYTITPNTLKTLVLVGCFSVFWTIYYMLEVCLSQRNKASTHGCRKGCCPWAPRRQNSKDAGTALESMPLCSSKDLDGVDSEHGDCTTASSFLAPELDCPPHQPPDLLQGKSGQIC", "length": 770 }, "evidence": [ { "id": "A0A8V0ZRB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62849-1", "protein_name": "Proprotein convertase subtilisin/kexin type 7", "gene_name": "Pcsk7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGRQKVPRLDARLGLPICLCLELAIFFLVPQVMGLTEAGGLDTLGAGGLSWAVHLDSLEGERKEESLIQQANAVAQAAGLVNAGRIGELQGHYLFVQPAGHGQAMEAEAMRQQAEAVLAKHEAVRWHSEQRLLKRAKRSIHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTVQDIAPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVMAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATQYEDHRADWLTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPMLKENKAVPRSPHSLEVLWNVSRTDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGVYRLVIRDVGDEPLQVGILQQWQLTLYGSTWSPVDIKDRQSLLESAMSGKYLHDDFTLPCPPGLKIPEEDGYSITPNTLKTLVLVGCFSVFWTIYYMLEVCLSQRSKASTHGCRRGCCPWPPQSQNSKEVGTALESMPLCSSKDLDGVDSEHGDCTTASSLLAPELLGEADWSLSQNSKSDLDCPPHQPPDLKDGQIC", "length": 783 }, "evidence": [ { "id": "A0A8V0ZRB7", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": 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"id": "ENSGALT00010059071.1", "url": "https://www.ensembl.org/id/ENSGALT00010059071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036035.1", "url": "https://www.ensembl.org/id/ENSGALP00010036035.1" } ] } }, { "isoform_ac": "A0A8V0ZYP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE8/entry#A0A8V0ZYP8-1", "sequence": { "sequence": "MVFRMKFLFPLLALAVIITSTFCGIKDFSDHFESLKDAHTHENGTYNMPDLPLEFHRENTITNDLIPEEEEEEDYLDLDKILGEDDYSDIIDAAPHIVSEIQQGNILELFQGKTRIQRLNILNANFGFNLYRSVADKANSSDNILMAPVGISTAMAMISLGLKGQTQQEVLSVLGFEDFINASAKYELMTVHNLFRKLTHRLFRRNFGYTLRSVNDLYIRKDFSILNDFRNNMKTYYFADAQPADFSDPNFITKTNERILKLTKGLIKEALVNVNPTTLMMILNCLYFKGTWENKFPVEMTTKRSFRLNEKQTIKVPMMQTKGNFLAAADPELDCGVIQLPFVGNISMLIVLPHKLSGMKALEKQITPQVVEKWQKSMTNRTREVVLPKFKLEKNYNLIGFLRSMGIEELFSEKGNYCGVSEEKVSIDRFNHQGTITVNEEGTEAGAITNVGFMPLSTQIRFIVDRPFLFLIYEHRTNCLLFMGRVVNPAKP", "length": 492, "header": "tr|A0A8V0ZYP8-1|A0A8V0ZRE8_CHICK Computationally mapped isoform of Serpin family D member 1 OS=Gallus gallus OX=9031 GN=SERPIND1 PE=1 SV=1 CANONICAL=A0A8V0ZRE8-1" }, "locus": { "chromosome": "15", "start_pos": 146020, "end_pos": 135270, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059070.1", "url": "https://www.ensembl.org/id/ENSGALT00010059070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036034.1", "url": "https://www.ensembl.org/id/ENSGALP00010036034.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:395877", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395877", "resource": "KEGG Pathway" }, { "id": "R-GGA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" }, { "id": "R-GGA-8957275", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8957275", "resource": "Reactome", "description": "Post-translational protein phosphorylation" }, { "id": "R-GGA-9769733", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769733", "resource": "Reactome", "description": "Fibrin formation" }, { "id": "R-GGA-9769739", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769739", "resource": "Reactome", "description": "Regulation of clotting cascade" }, { "id": "R-GGA-9769743", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9769743", "resource": "Reactome", "description": "Amplification and propagation of coagulation cascade" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A481BLI9-1", "protein_name": "Serpin family D member 1", "gene_name": "SERPIND1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQRSPHPLMLFLLLASVCGKHGLVGQPVDGGEDPKSADPRWGQMKSRNQSRPLLPTDFHKDTVTNEWIADGEEDEDYLDLEKIFGDDDDYIDIVDAVSPADPMASAGNVLQLFPGKSRIQRLNILNAKFAFNLYRALKEQASASDNIFLAPVGISTAMGMLCLGLRGETHKQVHAALHFTDFVNASSKYELGTIHNLFRKLTHRLFRRDFGYTLRAVNDLYVQRQFPILDDFRTKVRQYYFAEVQAADFADPAFLSETNHHVARLTKGLIKDTLQDIDPATQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVPMMQTKGAFLAASDQELDCEILQLDYVGGVSMLVVVPHKLSGMKTLEAQLTPQVVEKWQKSMTNRTREVLLPKFKLEKDYNLVEALRSVGVTALFDRNSNLTGISDQRIAIDLFKHHGTITVNEEGTQAAAVTTVGFMPLSTQARFSVDRPFLFLIHEHRTGCLLFMGRVANPARS", "length": 495 }, "evidence": [ { "id": "A0A8V0ZRE8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRE8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6R4P6-1", "protein_name": "Serpin family D member 1", "gene_name": "SERPIND1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWSRSCWAVTRHTAGLCADEAGGRCSICDLCTLEDLDCSPAPKVTEERGRPWPIPPLQSHFAPAAQSSSGMWCPLRPLLLALLLASACRTLGPWGQRDDGGGEPESMEPRWGRLKGSNASGPLPPAAFHEENTVTGEWAADGEEEEDYLDLEKIFGEDDNYSDVVDAAPPTRPGAGAGSVLPLFPGKSRVQRLNLLNAQFAFDLYRALAARVGAADNVFLAPVGVSAAMAMLSLGLAGDTHQEVHTALRFAEFVNASAAYELGTVHNLFRKLIHRLFRRNFGYTLRSVSDLYVQKQLPVLDDFKTQVREYYFAEVRAADFSDPAFLAHTNRHVARLTKGLIRDALQDVDPATQMLLLNCLYFKGSWVNKFPVEMTHNHNFRLNEREVVKVPMMQTKGAFLAASDQELDCDVLRLEYVGGISMLVVVPHKLSGMKTLESQLTPQAVERWQRSMTNRTREVLLPKFKLEKDYDLVGALRALGVTALFDKHSNTTGITGQRIVIDLFKHQGTITVNEEGTQAAAVTAVGFMPLSTQVRFSVDRPFLFLIYEHRTSCLLFLGRVANPTRP", "length": 566 }, "evidence": [ { "id": "A0A8V0ZRE8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRE8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HFZ7-1", "protein_name": "Heparin cofactor 2", "gene_name": "Serpind1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKHPLHPLLLSVILSVCVGSNGLAEQVANENVSVSFLPANFHKENTVTNDWIPEGEEEDDYLDLEKLFSEDDDYIYIIDAVSPTDAESSAGNILQLFQGKSRIQRLNIINAKFAFNLYRVLKDKATTSENIFIAPVGISTAMGMLSLGLSGETHEEVHSVLHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLQSANGLYIQKQLPVREDFKADMREFYFAEAQVADFSDPAFILKANNHILKLTKGLIKAALENIDPATQMMILNCIYFKGTWVNKFPVEMTHSHNFRLNEREVIKVSMMQTKGNFLAASDQELDCDILQLEYVGGISMLIVIPRKLSGMKTLEAQLTPQVVERWQKSMTNRTREVLLPKFKLEKNYNLVEVLKSMGITKVFDKNGNMSGISDQRITVDLFKHQSTITVDEEGTQAAAVTTVGFMPLSTQVRFAVDRPFLFLVYEHRTSCLLFMGRVANPTRS", "length": 479 }, "evidence": [ { "id": "A0A8V0ZRE8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRE8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P05546-1", "protein_name": "Heparin cofactor 2", "gene_name": "SERPIND1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MKHPLCTLLSLITFMCIGSKGLAEQLTNENLTTSFLPANFHKENTVTNDWIPEGEEDEDYLDLEKLLGEDDDYIYIIDAVSPTDSESSAGNILQLFQGKSRIQRLNILNAKFAFNLYRVLKDQATTSDNLFIAPVGISTAMGMISLGLRGETHEEVHSVLHFRDFVNASSKYEVTTIHNLFRKLTHRLFRRNFGYTLRSVNGLYIQKQFPIREDFKAAMREFYFAEAQEANFPDPAFISKANNHILKLTKGLIKEALENIDPATQMLILNCIYFKGTWVNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPRKLSGMKTLEAQLTPQVVERWQKSMTNRTREVLLPKFKLEKNYNLVEVLKSMGITKLFNKNGNMSGISDQRIAIDLFKHQSTITVNEEGTQAAAVTTVGFMPLSTQVRFTVDRPFLFLVYEHRTSCLLFMGKVTNPAKS", "length": 478 }, "evidence": [ { "id": "A0A8V0ZRE8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRE8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64268-1", "protein_name": "Heparin cofactor 2", "gene_name": "Serpind1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKHPAYTLLLSLIMSMCAGSKGLAEQLTKENLTVSLLPPNFHKENTVTNDWIPEGEEDDDYLDLEKLLSEDDDYIYVVDAVSPTDSESSAGNILQLFQGKSRIQRLNILNAKFAFNLYRVLKDQATSSDNIFIAPVGISTAMGMISLGLRGETHEEVHSVLHFKDFVNASSKYEVTTIHNLFRKLTHRLFRRNFGYTLQSVNDLYIQKQFPIREDFKAAMREFYFAEAQEADFSDPAFISKANSHILKLTKGLIKEALENTDSATQMMILNCIYFKGAWMNKFPVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVIPRKLSGMKTLEAQLTPQVVERWQKSMTNRTREVLLPKFKLEKNYNLVEVLKSMGITKLFNKNGNMSGISDQRIIIDLFKHQSTITVNEEGTQAAAVTTVGFMPLSTQVRFTVDRPFLFLVYEHRTSCLLFMGRVANPAKS", "length": 479 }, "evidence": [ { "id": "A0A8V0ZRE8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRE8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRE8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE8" }, { "id": "SM00093", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Serpin", "eco_id": "ECO_0000259", "start_pos": 131, "end_pos": 492, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQ30-1", "uniprot_ac": "A0A8V0ZQ30", "uniprot_id": "A0A8V0ZQ30_CHICK", "mass": { "chemical_mass": 49985.0, "monoisotopic_mass": 49985.0 }, "refseq": { "ac": "XP_015146473", "name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146473" }, "gene_names": [ { "name": "ST3GAL3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30" } ] }, { "name": "SIAT6", "type": "synonym", "evidence": [ { "id": "XP_015146473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146473" } ] }, { "name": "ST3GAL3", "type": "synonym", "evidence": [ { "id": "XP_015146473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146473" } ] } ], "protein_names": [ { "name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#names_and_taxonomy" } ] }, { "name": "2.4.3.6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#names_and_taxonomy" } ] }, { "name": "Beta-galactoside alpha-2,3-sialyltransferase 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#names_and_taxonomy" } ] }, { "name": "CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015146473", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146473" } ] }, { "name": "Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#names_and_taxonomy" } ] }, { "name": "N-acetyllactosaminide alpha-2,3-sialyltransferase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#names_and_taxonomy" } ] }, { "name": "ST3Gal III", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#names_and_taxonomy" } ] }, { "name": "ST3N", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#names_and_taxonomy" } ] }, { "name": "Sialyltransferase 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146473" } ] }, { "annotation": "Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5PQ75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ75#function" }, { "database": "UniProtKB", "id": "ARBA00056237", "url": "https://www.uniprot.org/uniprotkb/ARBA00056237#function" }, { "database": "UniProtKB", "id": "A0A8V0ZBZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ7#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJ79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ79#function" }, { "database": "UniProtKB", "id": "A0A8V0ZJ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ85#function" }, { "database": "UniProtKB", "id": "A0A8V0ZQ30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ST3GAL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30", "locus": { "chromosome": "8", "start_pos": 20020381, "end_pos": 19869716, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021309", "url": "https://www.ensembl.org/id/ENSGALG00010021309" } ] } } ], "crossref": [ { "id": "A0A8V0ZQ30", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQ30", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010083", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010083", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23981", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23981", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424572", "url": "https://www.ncbi.nlm.nih.gov/gene/424572", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PQ75", "url": "https://www.orthodb.org/?gene=A0A1D5PQ75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBZ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZBZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHM8", "url": "https://www.orthodb.org/?gene=A0A8V0ZHM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHQ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZHQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ79", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJ85", "url": "https://www.orthodb.org/?gene=A0A8V0ZJ85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ30", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13713", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13713", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13713:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13713:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2022854", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022854", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-4085001", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085001", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9037629", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9037629", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-977068", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977068", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9840309", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840309", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015146473", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146473", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "52316", "url": "https://www.rhea-db.org/rhea/52316", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PQ75", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PQ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PQ75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHM8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRWDCWCSCATCCSPSACSWCWAFCTTPPGSCTSSAGRTPESQWDGPVSSYFQLSWVTVSACDCRLPKYSVVLSFDSVGHTIGSGRRERKAVAIVLPLSIPSHLAADPGKDRAQKEPKETMAAADPAIPKYDKLGFLLNLDSKLPPELASKYANFSEGVCKPGYASALMTVIFPKFSKPAPMFLDDSFRRWARIRDFVPPFGIKGQDNLIKAILSATKDYRLTPALDSLSCRRCIIVGNGGVLANKSLGLKIDDYDVVVRLNSAPVKGFEKDVGGKTTLRITYPEGAIQKMEQYEKDSLFVLAGFKWQDFKWLKYIVYKEKVSASDGFWKSVATRVPREPHEIRILNPYFIQEAAFSFIGLPFNNGLMGRGNIPTLGSVAITMALHNCDEVAVAGFGYDMSSPNAPLHYYENIKMSAIKESWTHNIQREKEFLRKLVKARVITDLTSGI", "length": 450, "header": "tr|A0A8V0ZQ30-1|A0A8V0ZQ30_CHICK Isoform 1 of CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase OS=Gallus gallus OX=9031 GN=ST3GAL3 PE=3 SV=1 CANONICAL=A0A8V0ZQ30-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PQ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#A0A1D5PQ75-1", "sequence": { "sequence": "MGLLVFMRNLLLALCLFLVLGFLYYSAWKLHLLRWEDSKYDKLGFLLNLDSKLPPELASKYANFSEGVCKPGYASALMTVIFPKFSKPAPMFLDDSFRRWARIRDFVPPFGIKGQDNLIKAILSATKDYRLTPALDSLSCRRCIIVGNGGVLANKSLGLKIDDYDVVVRLNSAPVKGFEKDVGGKTTLRITYPEGAIQKMEQYEKDSLFVLAGFKWQDFKWLKYIVYKEKVSASDGFWKSVATRVPREPHEIRILNPYFIQEAAFSFIGLPFNNGLMGRGNIPTLGSVAITMALHNCDEVAVAGFGYDMSSPNAPLHYYENIKMSAIKESWTHNIQREKEFLRKLVKARVITDLTSGI", "length": 358, "header": "tr|A0A1D5PQ75-1|A0A8V0ZQ30_CHICK Computationally mapped isoform of CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase OS=Gallus gallus OX=9031 GN=ST3GAL3 PE=3 SV=1 CANONICAL=A0A8V0ZQ30-1" }, "locus": { "chromosome": "8", "start_pos": 20017116, "end_pos": 19875243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051705.1", "url": "https://www.ensembl.org/id/ENSGALT00010051705.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030840.1", "url": "https://www.ensembl.org/id/ENSGALP00010030840.1" } ] } }, { "isoform_ac": "A0A8V0ZBZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#A0A8V0ZBZ7-1", "sequence": { "sequence": "MGVTSSIKDVGSKLYDSVVLSFDSVGHTIGSGRRERKAVAIVLPLSIPSHLAADPGKDRAQKEPKETMAAADPAIPKYDKLGFLLNLDSKLPPELASKYANFSEGVCKPGYASALMTVIFPKFSKPAPMFLDDSFRRWARIRDFVPPFGIKGQDNLIKAILSATKDYRLTPALDSLSCRRCIIVGNGGVLANKSLGLKIDDYDVVVRLNSAPVKGFEKDVGGKTTLRITYPEGAIQKMEQYEKDSLFVLAGFKWQDFKWLKYIVYKEKVSASDGFWKSVATRVPREPHEIRILNPYFIQEAAFSFIGLPFNNGLMGRGNIPTLGSVAITMALHNCDEVAVAGFGYDMSSPNAPLHYYENIKMSAIKESWTHNIQREKEFLRKLVKARVITDLTSGI", "length": 396, "header": "tr|A0A8V0ZBZ7-1|A0A8V0ZQ30_CHICK Computationally mapped isoform of CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase OS=Gallus gallus OX=9031 GN=ST3GAL3 PE=3 SV=1 CANONICAL=A0A8V0ZQ30-1" }, "locus": { "chromosome": "8", "start_pos": 20017116, "end_pos": 19902317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051645.1", "url": "https://www.ensembl.org/id/ENSGALT00010051645.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030802.1", "url": "https://www.ensembl.org/id/ENSGALP00010030802.1" } ] } }, { "isoform_ac": "A0A8V0ZHM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#A0A8V0ZHM8-1", "sequence": { "sequence": "MKDRPAWLSCPSVVRGFLLILILRDFILSEEYDKLGFLLNLDSKLPPELASKYANFSEGVCKPGYASALMTVIFPKFSKPAPMFLDDSFRRWARIRDFVPPFGIKGQDNLIKAILSATKDYRLTPALDSLSCRRCIIVGNGGVLANKSLGLKIDDYDVVVRLNSAPVKGFEKDVGGKTTLRITYPEGAIQKMEQYEKDSLFVLAGFKWQDFKWLKYIVYKEKVSASDGFWKSVATRVPREPHEIRILNPYFIQEAAFSFIGLPFNNGLMGRGNIPTLGSVAITMALHNCDEVAVAGFGYDMSSPNAPLHYYENIKMSAIKESWTHNIQREKEFLRKLVKARVITDLTSGI", "length": 350, "header": "tr|A0A8V0ZHM8-1|A0A8V0ZQ30_CHICK Computationally mapped isoform of CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase OS=Gallus gallus OX=9031 GN=ST3GAL3 PE=3 SV=1 CANONICAL=A0A8V0ZQ30-1" }, "locus": { "chromosome": "8", "start_pos": 20017116, "end_pos": 19888781, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051658.1", "url": "https://www.ensembl.org/id/ENSGALT00010051658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030809.1", "url": "https://www.ensembl.org/id/ENSGALP00010030809.1" } ] } }, { "isoform_ac": "A0A8V0ZHQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#A0A8V0ZHQ2-1", "sequence": { "sequence": "MGLLVFMRNLLLALCLFLVLGFLYYSAWKLHLLRWEDSNSVVLSFDSVGHTIGSGRRERKAVAIVLPLSIPSHLAADPGKDRAQKEPKETMAAADPAIPKYDKLGFLLNLDSKLFSKPAPMFLDDSFRRWARIRDFVPPFGIKGQDNLIKAILSATKDYRLTPALDSLSCRRCIIVGNGGVLANKSLGLKIDDYDVVVRLNSAPVKGFEKDVGGKTTLRITYPEGAIQKMEQYEKDSLFVLAGFKWQDFKWLKYIVYKEKVSASDGFWKSVATRVPREPHEIRILNPYFIQEAAFSFIGLPFNNGLMGRGNIPTLGSVAITMALHNCDEVAVAGFGYDMSSPNAPLHYYENIKMSAIKESWTHNIQREKEFLRKLVKARVITDLTSGI", "length": 388, "header": "tr|A0A8V0ZHQ2-1|A0A8V0ZQ30_CHICK Computationally mapped isoform of CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase OS=Gallus gallus OX=9031 GN=ST3GAL3 PE=3 SV=1 CANONICAL=A0A8V0ZQ30-1" }, "locus": { "chromosome": "8", "start_pos": 20017116, "end_pos": 19875243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051696.1", "url": "https://www.ensembl.org/id/ENSGALT00010051696.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030834.1", "url": "https://www.ensembl.org/id/ENSGALP00010030834.1" } ] } }, { "isoform_ac": "A0A8V0ZJ79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#A0A8V0ZJ79-1", "sequence": { "sequence": "MGLLVFMRNLLLALCLFLVLGFLYYSAWKLHLLRWEDSRRRERKAVAIVLPLSIPSHLAADPGKDRAQKEPKETMAAADPAIPKYDKLGFLLNLDSKLPPELASKYANFSEGVCKPGYASALMTVIFPKFSKPAPMFLDDSFRRWARIRDFVPPFGIKGQDNLIKAILSATKDYRLTPALDSLSCRRCIIVGNGGVLANKSLGLKIDDYDVVVRLNSAPVKGFEKDVGGKTTLRITYPEGAIQKMEQYEKDSLFVLAGFKWQDFKWLKYIVYKEKVSASDGFWKSVATRVPREPHEIRILNPYFIQEAAFSFIGLPFNNGLMGRGNIPTLGSVAITMALHNCDEVAVAGFGYDMSSPNAPLHYYENIKMSAIKESWTHNIQREKEFLRKLVKARVITDLTSGI", "length": 403, "header": "tr|A0A8V0ZJ79-1|A0A8V0ZQ30_CHICK Computationally mapped isoform of CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase OS=Gallus gallus OX=9031 GN=ST3GAL3 PE=3 SV=1 CANONICAL=A0A8V0ZQ30-1" }, "locus": { "chromosome": "8", "start_pos": 20017116, "end_pos": 19875243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051719.1", "url": "https://www.ensembl.org/id/ENSGALT00010051719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030851.1", "url": "https://www.ensembl.org/id/ENSGALP00010030851.1" } ] } }, { "isoform_ac": "A0A8V0ZJ85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#A0A8V0ZJ85-1", "sequence": { "sequence": "MNLYSCVTDSVVLSFDSVGHTIGSEYDKLGFLLNLDSKLPPELASKYANFSEGVCKPGYASALMTVIFPKFSKPAPMFLDDSFRRWARIRDFVPPFGIKGQDNLIKAILSATKDYRLTPALDSLSCRRCIIVGNGGVLANKSLGLKIDDYDVVVRLNSAPVKGFEKDVGGKTTLRITYPEGAIQKMEQYEKDSLFVLAGFKWQDFKWLKYIVYKEKVSASDGFWKSVATRVPREPHEIRILNPYFIQEAAFSFIGLPFNNGLMGRGNIPTLGSVAITMALHNCDEVAVAGFGYDMSSPNAPLHYYENIKMSAIKESWTHNIQREKEFLRKLVKARVITDLTSGI", "length": 344, "header": "tr|A0A8V0ZJ85-1|A0A8V0ZQ30_CHICK Computationally mapped isoform of CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase OS=Gallus gallus OX=9031 GN=ST3GAL3 PE=3 SV=1 CANONICAL=A0A8V0ZQ30-1" }, "locus": { "chromosome": "8", "start_pos": 20017116, "end_pos": 19902761, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051683.1", "url": "https://www.ensembl.org/id/ENSGALT00010051683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030825.1", "url": "https://www.ensembl.org/id/ENSGALP00010030825.1" } ] } }, { "isoform_ac": "A0A8V0ZQ30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30/entry#A0A8V0ZQ30-1", "sequence": { "sequence": "MRRWDCWCSCATCCSPSACSWCWAFCTTPPGSCTSSAGRTPESQWDGPVSSYFQLSWVTVSACDCRLPKYSVVLSFDSVGHTIGSGRRERKAVAIVLPLSIPSHLAADPGKDRAQKEPKETMAAADPAIPKYDKLGFLLNLDSKLPPELASKYANFSEGVCKPGYASALMTVIFPKFSKPAPMFLDDSFRRWARIRDFVPPFGIKGQDNLIKAILSATKDYRLTPALDSLSCRRCIIVGNGGVLANKSLGLKIDDYDVVVRLNSAPVKGFEKDVGGKTTLRITYPEGAIQKMEQYEKDSLFVLAGFKWQDFKWLKYIVYKEKVSASDGFWKSVATRVPREPHEIRILNPYFIQEAAFSFIGLPFNNGLMGRGNIPTLGSVAITMALHNCDEVAVAGFGYDMSSPNAPLHYYENIKMSAIKESWTHNIQREKEFLRKLVKARVITDLTSGI", "length": 450, "header": "tr|A0A8V0ZQ30-1|A0A8V0ZQ30_CHICK Isoform 1 of CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase OS=Gallus gallus OX=9031 GN=ST3GAL3 PE=3 SV=1 CANONICAL=A0A8V0ZQ30-1" }, "locus": { "chromosome": "8", "start_pos": 20017116, "end_pos": 19875235, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051709.1", "url": "https://www.ensembl.org/id/ENSGALT00010051709.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030843.1", "url": "https://www.ensembl.org/id/ENSGALP00010030843.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-2022854", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2022854", "resource": "Reactome", "description": "Keratan sulfate biosynthesis" }, { "id": "R-GGA-4085001", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4085001", "resource": "Reactome", "description": "Sialic acid metabolism" }, { "id": "R-GGA-9037629", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9037629", "resource": "Reactome", "description": "Lewis blood group biosynthesis" }, { "id": "R-GGA-977068", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977068", "resource": "Reactome", "description": "Termination of O-glycan biosynthesis" }, { "id": "R-GGA-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30" } ], "pmid": "" }, { "name": "Golgi cisterna membrane", "id": "GO:0032580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032580", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glycoprotein biosynthetic process", "id": "GO:0009101", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009101", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30" } ], "pmid": "" }, { "name": "ganglioside biosynthetic process", "id": "GO:0001574", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001574", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "N-acetyllactosaminide alpha-2,3-sialyltransferase activity", "id": "GO:0008118", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008118", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30" } ], "pmid": "" }, { "name": "sialyltransferase activity", "id": "GO:0008373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008373", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30" } ], "pmid": "" }, { "name": "beta-galactoside (CMP) alpha-2,3-sialyltransferase activity", "id": "GO:0003836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003836", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "52316", "name": "", "equation": "a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XRF2-1", "A0A8V1A329-1", "A0A8V0ZQ30-1" ], "evidence": [ { "id": "52316", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/52316" } ] }, { "id": "R-GGA-2046285", "name": "ST3GAL1-4,6 optionally cap keratan chain", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XRF2-1", "A0A8V0ZLV8-1", "A0A8V1A329-1", "Q11200-1", "A0A8V0ZQ30-1" ], "evidence": [ { "id": "R-GGA-2046285", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2046285" } ] }, { "id": "R-GGA-4084984", "name": "ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [ "R-ALL-727815", "R-ALL-4086285" ], "output_participant_list": [ "R-ALL-4086277" ], "enzyme_list": [ "A0A8V0XRF2-1", "A0A8V0ZLV8-1", "A0A8V0Z4G1-1", "A0A8V1A329-1", "Q11200-1", "A0A8V0ZQ30-1" ], "evidence": [ { "id": "R-GGA-4084984", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-4084984" } ] }, { "id": "R-GGA-9603987", "name": "ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [ "R-ALL-9605595" ], "enzyme_list": [ "A0A8V0ZQ30-1" ], "evidence": [ { "id": "R-GGA-9603987", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9603987" } ] }, { "id": "R-GGA-9605600", "name": "ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XRF2-1", "A0A8V1A329-1", "A0A8V0ZQ30-1" ], "evidence": [ { "id": "R-GGA-9605600", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9605600" } ] }, { "id": "R-GGA-981497", "name": "ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZLV8-1", "A0A8V1A329-1", "Q11200-1", "A0A8V0ZQ30-1" ], "evidence": [ { "id": "R-GGA-981497", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-981497" } ] }, { "id": "R-GGA-9845538", "name": "ST3GAL2,3 transfer Neu5Ac to gangliosides", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "Golgi lumen, Golgi membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZLV8-1", "A0A8V0ZQ30-1" ], "evidence": [ { "id": "R-GGA-9845538", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9845538" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-4086277", "participant_name": "Neu5Ac-2,3-Gal-R [Golgi lumen]", "crossref": [ { "id": "75127", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-4086285", "participant_name": "Gal-R [Golgi lumen]", "crossref": [ { "id": "61248", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-727815", "participant_name": "CMP-Neu5Ac [Golgi lumen]", "crossref": [ { "id": "57812", "database": "ChEBI", "url": "" }, { "id": "ZINC000008215638", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9605595", "participant_name": "Type 1 MSGG [Golgi lumen]", "crossref": [ { "id": "140917", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XRF2", "gene_name": "ST3GAL6", "activity": [ { "ec_number": "2.4.3.6", "activity": "a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "A0A8V0XRF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRF2" } ] }, { "ec_number": "2.4.3.6", "activity": "", "evidence": [ { "id": "A0A8V0XRF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XRF2" } ] } ] }, { "uniprot_ac": "A0A8V0Z4G1", "gene_name": "ST3GAL5", "activity": [ { "ec_number": "2.4.3.9", "activity": "a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM3 (d18:1(4E)) + CMP + H(+).", "evidence": [ { "id": "A0A8V0Z4G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G1" } ] }, { "ec_number": "2.4.3.9", "activity": "", "evidence": [ { "id": "A0A8V0Z4G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G1" } ] } ] }, { "uniprot_ac": "A0A8V0ZLV8", "gene_name": "ST3GAL2", "activity": [ { "ec_number": "2.4.3.2", "activity": "a ganglioside GM1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a (d18:1(4E)) + CMP + H(+).", "evidence": [ { "id": "A0A8V0ZLV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV8" } ] }, { "ec_number": "2.4.3.4", "activity": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "A0A8V0ZLV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV8" } ] }, { "ec_number": "2.4.3.4", "activity": "", "evidence": [ { "id": "A0A8V0ZLV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV8" } ] }, { "ec_number": "2.4.3.2", "activity": "", "evidence": [ { "id": "A0A8V0ZLV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLV8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ30", "gene_name": "ST3GAL3", "activity": [ { "ec_number": "2.4.3.6", "activity": "a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "A0A8V0ZQ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30" } ] }, { "ec_number": "2.4.3.6", "activity": "", "evidence": [ { "id": "A0A8V0ZQ30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ30" } ] } ] }, { "uniprot_ac": "A0A8V1A329", "gene_name": "ST3GAL4", "activity": [ { "ec_number": "2.4.3.2", "activity": "a ganglioside GM1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a (d18:1(4E)) + CMP + H(+).", "evidence": [ { "id": "A0A8V1A329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A329" } ] }, { "ec_number": "2.4.3.4", "activity": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "A0A8V1A329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A329" } ] }, { "ec_number": "2.4.3.6", "activity": "a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "A0A8V1A329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A329" } ] }, { "ec_number": "2.4.3.6", "activity": "", "evidence": [ { "id": "A0A8V1A329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A329" } ] }, { "ec_number": "2.4.3.2", "activity": "", "evidence": [ { "id": "A0A8V1A329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A329" } ] }, { "ec_number": "2.4.3.4", "activity": "", "evidence": [ { "id": "A0A8V1A329", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A329" } ] } ] }, { "uniprot_ac": "Q11200", "gene_name": "ST3GAL1", "activity": [ { "ec_number": "2.4.3.4", "activity": "a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "Q11200", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q11200" } ] }, { "ec_number": "2.4.3.4", "activity": "", "evidence": [ { "id": "Q11200", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q11200" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.4.3.6", "ec_name": "a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+).", "evidence": [ { "id": "2.4.3.6", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.4.3.6" }, { "id": "2.4.3.6", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.4.3.6" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 246, "end_pos": 248 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQ70-1", "uniprot_ac": "A0A8V0ZQ70", "uniprot_id": "A0A8V0ZQ70_CHICK", "mass": { "chemical_mass": 151009.0, "monoisotopic_mass": 151009.0 }, "refseq": { "ac": "XP_015132340", "name": "GRB10-interacting GYF protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132340" }, "gene_names": [ { "name": "GIGYF2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70" } ] }, { "name": "GIGYF2", "type": "synonym", "evidence": [ { "id": "XP_015132340", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132340" } ] }, { "name": "TNRC15", "type": "synonym", "evidence": [ { "id": "XP_015132340", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132340" } ] } ], "protein_names": [ { "name": "GRB10 interacting GYF protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70/entry#names_and_taxonomy" } ] }, { "name": "GRB10-interacting GYF protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_015132340", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132340" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132340", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132340" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GIGYF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70", "locus": { "chromosome": "9", "start_pos": 679520, "end_pos": 606047, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022811", "url": "https://www.ensembl.org/id/ENSGALG00010022811" } ] } } ], "crossref": [ { "id": "ENSGALG00000038730", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038730", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00072", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00072", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424743", "url": "https://www.ncbi.nlm.nih.gov/gene/424743", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424743", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424743", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PV32", "url": "https://www.orthodb.org/?gene=A0A1D5PV32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ65", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ70", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS19", "url": "https://www.orthodb.org/?gene=A0A8V0ZS19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14445", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14445", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14445:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14445:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02213", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02213", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015132340", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132340", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PV32", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PV32-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAETQTLNFGPEWLRALSSGGSVTSPPLSPALPKYKLADYRYGREEMLALFVKDNKIPSDLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAVVLRLTGRGGGTVVGAPRGRSSSRGRGRGRGESGFYQRSFDEVEGGFGRGGGREMHRSQSWEERGDRRFEKPGRKDPVRPNFEEGGTAATGRKHEFIRSESENWRIFREEQNGEDDDGGWRLAGSRRDGERWRPHSPGWREHMERRRRFEFDFRERDDERGYRRVRCGSGSMDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEERSDSEGSHSEDAKNHEKTTRKEGEKTDRIVSEAAEEAVQTSSPATRSESPPKSQLQDSPQTSLFERKEESVPERTEKTEDKESRTENTPPAKLSSRGEDLASAAQPLPQRSADTASPAHLSPPVSNSNPALRPVQTPVTAAPGMGNVPTDPDDEEGLKHLEQQAEKMVAYLQDSAVDDERLAAKIQEHRAKGSSMPLFHEAMQKWYYKDPQGEIQGPFSNQEMAEWFQAGYFTMSLLIKRACDETFQPLGDIMKMWGRVPFTSGPTPLPHLGELDQERLTRQQELALIQMQHLQYQHLLIQQQYAQVLAQQQKAALSSQQQQQLAILLQQFQALKIRISEQNMMPPVTRSVSVPDTGSIWELQSASQPTVWEGSSVWDLPLDTAAQGPALEQLQQLEKAKAAKLEQERREVEMRAKREEEERKRQEELRRQQEELLRRQQEDERKRREEEELARRKQEMAVRAERGEAVDLICLDIRKAFDVILHKRLVYKEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRQREELIRKQEEEAAKWAREEEEAQRRLEESRLRMEEEAARQRLEEEERKRKELELQRQKEIMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNSGACQSQTTLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVTKPTGTTKSLLEIQQEEARQMQKQQQQQHQQPNRVRNTTHSNLHTSIGNSVWGSLNTNPSNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKSNASLSKSVGITSRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTPEAKEFAKQFLERRAKQKASQQRQQQQQQDSVWGMNHSSLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLEDY", "length": 1306, "header": "tr|A0A8V0ZQ70-1|A0A8V0ZQ70_CHICK Isoform 1 of GRB10 interacting GYF protein 2 OS=Gallus gallus OX=9031 GN=GIGYF2 PE=1 SV=1 CANONICAL=A0A8V0ZQ70-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PV32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70/entry#A0A1D5PV32-1", "sequence": { "sequence": "MAAETQTLNFGPEWLRALSSGGSVTSPPLSPALPKYKLADYRYGREEMLALFVKDNKIPSDLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAVVLRLTGRGGGTVVGAPRGRSSSRGRGRGRGESGFYQRSFDEVEGGFGRGGGREMHRSQSWEERGDRRFEKPGRKDPVRPNFEEGGTAATGRKHEFIRSESENWRIFREEQNGEDDDGGWRLAGSRRDGERWRPHSPDGPRSTGWREHMERRRRFEFDFRERDDERGYRRVRCGSGSMDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEERSDSEGSHSEDAKNHEKTTRKEGEKTDRIVSEAAEEAVQTSSPATRSESPPKSQLQDSPQTSLFERKEESVPERTEKTEDKESRTENTPPAKLSSRGEDLASAAQPLPQRSADTASPAHLSPPVSNSNPALRPVQTPVTAAPGMGNVPTDPDDEEGLKHLEQQAEKMVAYLQDSAVDDERLAAKIQEHRAKGSSMPLFHEAMQKWYYKDPQGEIQGPFSNQEMAEWFQAGYFTMSLLIKRACDETFQPLGDIMKMWGRVPFTSGPTPLPHLGELDQERLTRQQELALIQMQHLQYQHLLIQQQYAQVLAQQQKAALSSQQQQQLAILLQQFQALKIRISEQNMMPPVTRSVSVPDTGSIWELQSASQPTVWEGSSVWDLPLDTAAQGPALEQLQQLEKAKAAKLEQERREVEMRAKREEEERKRQEELRRQQEELLRRQQEDERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRQREELIRKQEEEAAKWAREEEEAQRRLEESRLRMEEEAARQRLEEEERKRKELELQRQKEIMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNSGACQSQTTLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVTKPTGTTKSLLEIQQEEARQMQKQQQQQHQQPNRVRNTTHSNLHTSIGNSVWGSLNTNPSNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKSNASLSKSVGITSRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTPEAKEFAKQFLERRAKQKASQQRQQQQQQDSVWGMNHSSLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLEDY", "length": 1278, "header": "tr|A0A1D5PV32-1|A0A8V0ZQ70_CHICK Computationally mapped isoform of GRB10 interacting GYF protein 2 OS=Gallus gallus OX=9031 GN=GIGYF2 PE=1 SV=2 CANONICAL=A0A8V0ZQ70-1" }, "locus": { "chromosome": "9", "start_pos": 677831, "end_pos": 617667, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055483.1", "url": "https://www.ensembl.org/id/ENSGALT00010055483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033603.1", "url": "https://www.ensembl.org/id/ENSGALP00010033603.1" } ] } }, { "isoform_ac": "A0A8V0ZQ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70/entry#A0A8V0ZQ65-1", "sequence": { "sequence": "MAAETQTLNFGPEWLRALSSGGSVTSPPLSPALPKYKLADYRYGREEMLALFVKDNKIPSDLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAVVLRLTGRGGGTVVGAPRGRSSSRGRGRGRGESGFYQRSFDEVEGGFGRGGGREMHRSQSWEERGDRRFEKPGRKDPVRPNFEEGGTAATGRKHEFIRSESENWRIFREEQNGEDDDGGWRLAGSRRDGERWRPHSPGWREHMERRRRFEFDFRERDDERGYRRVRCGSGSMDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEERSDSEGSHSEDAKNHEKTTRKEGEKTDRIVSEPYNVTEAAEEAVQTSSPATRSESPPKSQLQDSPQTSLFERKEESVPERTEKTEDKESRTENTPPAKLSSRGEDLASAAQPLPQRSADTASPAHLSPPVSNSNPALRPVQTPVTAAPGMGNVPTDPDDEEGLKHLEQQAEKMVAYLQDSAVDDERLAAKIQEHRAKGSSMPLFHEAMQKWYYKDPQGEIQGPFSNQEMAEWFQAGYFTMSLLIKRACDETFQPLGDIMKMWGRVPFTSGPTPLPHLGELDQERLTRQQELALIQMQHLQYQHLLIQQQYAQVLAQQQKAALSSQQQQQLAILLQQFQALKIRISEQNMMPPVTRSVSVPDTGSIWELQSASQPTVWEGSSVWDLPLDTAAQGPALEQLQQLEKAKAAKLEQERREVEMRAKREEEERKRQEELRRQQEELLRRQQEDERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRQREELIRKQEEEAAKWAREEEEAQRRLEESRLRMEEEAARQRLEEEERKRKELELQRQKEIMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNSGACQSQTTLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVTKPTGTTKSLLEIQQEEARQMQKQQQQQHQQPNRVRNTTHSNLHTSIGNSVWGSLNTNPSNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKSNASLSKSVGITSRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTPEAKEFAKQFLERRAKQKASQQRQQQQQQDSVWGMNHSSLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLEDY", "length": 1278, "header": "tr|A0A8V0ZQ65-1|A0A8V0ZQ65_CHICK Computationally mapped isoform of GRB10 interacting GYF protein 2 OS=Gallus gallus OX=9031 GN=GIGYF2 PE=1 SV=1 CANONICAL=A0A8V0ZQ70-1" }, "locus": { "chromosome": "9", "start_pos": 677831, "end_pos": 617667, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055486.1", "url": "https://www.ensembl.org/id/ENSGALT00010055486.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033606.1", "url": "https://www.ensembl.org/id/ENSGALP00010033606.1" } ] } }, { "isoform_ac": "A0A8V0ZQ70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70/entry#A0A8V0ZQ70-1", "sequence": { "sequence": "MAAETQTLNFGPEWLRALSSGGSVTSPPLSPALPKYKLADYRYGREEMLALFVKDNKIPSDLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAVVLRLTGRGGGTVVGAPRGRSSSRGRGRGRGESGFYQRSFDEVEGGFGRGGGREMHRSQSWEERGDRRFEKPGRKDPVRPNFEEGGTAATGRKHEFIRSESENWRIFREEQNGEDDDGGWRLAGSRRDGERWRPHSPGWREHMERRRRFEFDFRERDDERGYRRVRCGSGSMDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEERSDSEGSHSEDAKNHEKTTRKEGEKTDRIVSEAAEEAVQTSSPATRSESPPKSQLQDSPQTSLFERKEESVPERTEKTEDKESRTENTPPAKLSSRGEDLASAAQPLPQRSADTASPAHLSPPVSNSNPALRPVQTPVTAAPGMGNVPTDPDDEEGLKHLEQQAEKMVAYLQDSAVDDERLAAKIQEHRAKGSSMPLFHEAMQKWYYKDPQGEIQGPFSNQEMAEWFQAGYFTMSLLIKRACDETFQPLGDIMKMWGRVPFTSGPTPLPHLGELDQERLTRQQELALIQMQHLQYQHLLIQQQYAQVLAQQQKAALSSQQQQQLAILLQQFQALKIRISEQNMMPPVTRSVSVPDTGSIWELQSASQPTVWEGSSVWDLPLDTAAQGPALEQLQQLEKAKAAKLEQERREVEMRAKREEEERKRQEELRRQQEELLRRQQEDERKRREEEELARRKQEMAVRAERGEAVDLICLDIRKAFDVILHKRLVYKEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRQREELIRKQEEEAAKWAREEEEAQRRLEESRLRMEEEAARQRLEEEERKRKELELQRQKEIMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNSGACQSQTTLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVTKPTGTTKSLLEIQQEEARQMQKQQQQQHQQPNRVRNTTHSNLHTSIGNSVWGSLNTNPSNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKSNASLSKSVGITSRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTPEAKEFAKQFLERRAKQKASQQRQQQQQQDSVWGMNHSSLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLEDY", "length": 1306, "header": "tr|A0A8V0ZQ70-1|A0A8V0ZQ70_CHICK Isoform 1 of GRB10 interacting GYF protein 2 OS=Gallus gallus OX=9031 GN=GIGYF2 PE=1 SV=1 CANONICAL=A0A8V0ZQ70-1" }, "locus": { "chromosome": "9", "start_pos": 677831, "end_pos": 617667, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055493.1", "url": "https://www.ensembl.org/id/ENSGALT00010055493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033611.1", "url": "https://www.ensembl.org/id/ENSGALP00010033611.1" } ] } }, { "isoform_ac": "A0A8V0ZS19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70/entry#A0A8V0ZS19-1", "sequence": { "sequence": "MAAETQTLNFGPEWLRALSSGGSVTSPPLSPALPKYKLADYRYGREEMLALFVKDNKIPSDLLDKEFLPILQEEPLPPLALVPFTEEEQRNFSMSVNSAVVLRLTGRGGGTVVGAPRGRSSSRGRVRPNFEEGGTAATGRKHEFIRSESENWRIFREEQNGEDDDGGWRLAGSRRDGERWRPHSPGWREHMERRRRFEFDFRERDDERGYRRVRCGSGSMDDDRDSLPEWCLEDAEEEMGTFDSSGAFLSLKKVQKEPIPEEQEMDFRPVDEGEERSDSEGSHSEDAKNHEKTTRKEGEKTDRIVSEAAEEAVQTSSPATRSESPPKSQLQDSPQTSLFERKEESVPERTEKTEDKESRTENTPPAKLSSRGEDLASAAQPLPQRSADTASPAHLSPPVSNSNPALRPVQTPVTAAPGMGNVPTDPDDEEGLKHLEQQAEKMVAYLQDSAVDDERLAAKIQEHRAKGSSMPLFHEAMQKWYYKDPQGEIQGPFSNQEMAEWFQAGYFTMSLLIKRACDETFQPLGDIMKMWGRVPFTSGPTPLPHLGELDQERLTRQQELALIQMQHLQYQHLLIQQQYAQVLAQQQKAALSSQQQQQLAILLQQFQALKIRISEQNMMPPVTRSVSVPDTGSIWELQSASQPTVWEGSSVWDLPLDTAAQGPALEQLQQLEKAKAAKLEQERREVEMRAKREEEERKRQEELRRQQEELLRRQQEDERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRQREELIRKQEEEAAKWAREEEEAQRRLEESRLRMEEEAARQRLEEEERKRKELELQRQKEIMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNSGACQSQTTLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVTKPTGTTKSLLEIQQEEARQMQKQQQQQHQQPNRVRNTTHSNLHTSIGNSVWGSLNTNPSNQWASDLVSSIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKSNASLSKSVGITSRQNKKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTPEAKEFAKQFLERRAKQKASQQRQQQQQQDSVWGMNHSSLHSVFQTNQSNNQQSNFEAVQSGKKKKKQKMVRADPSLLGFSVNASSERLNMGEIETLEDY", "length": 1221, "header": "tr|A0A8V0ZS19-1|A0A8V0ZQ70_CHICK Computationally mapped isoform of GRB10 interacting GYF protein 2 OS=Gallus gallus OX=9031 GN=GIGYF2 PE=1 SV=1 CANONICAL=A0A8V0ZQ70-1" }, "locus": { "chromosome": "9", "start_pos": 677831, "end_pos": 617667, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055500.1", "url": "https://www.ensembl.org/id/ENSGALT00010055500.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033618.1", "url": "https://www.ensembl.org/id/ENSGALP00010033618.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 592, "start_aa": "Thr", "end_pos": 592, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr592", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424743", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424743", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70" } ], "pmid": "" }, { "name": "negative regulation of translational initiation", "id": "GO:0045947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045947", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70" } ], "pmid": "" }, { "name": "insulin-like growth factor receptor signaling pathway", "id": "GO:0048009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70" } ], "pmid": "" }, { "name": "mRNA destabilization", "id": "GO:0061157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70" } ], "pmid": "" }, { "name": "negative regulation of type I interferon-mediated signaling pathway", "id": "GO:0060339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060339", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70" } ], "pmid": "" }, { "name": "post-transcriptional gene silencing", "id": "GO:0016441", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016441", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "mRNA regulatory element binding translation repressor activity", "id": "GO:0000900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70" } ], "pmid": "" }, { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70" } ], "pmid": "" }, { "name": "proline-rich region binding", "id": "GO:0070064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ70" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "endosome", 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"table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQK4-1", "uniprot_ac": "A0A8V0ZQK4", "uniprot_id": "A0A8V0ZQK4_CHICK", "mass": { "chemical_mass": 60710.0, "monoisotopic_mass": 60710.0 }, "refseq": {}, "gene_names": [ { "name": "SYT9", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ] } ], "protein_names": [ { "name": "Synaptotagmin 9", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "common_name": "Chicken", "glygen_name": "Chicken", 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"MPGDREDEICQKALQLLAELCSVGAVENENCRDFIYYLRDRARPRLTDSDISISLLSLVVTACGLALFGVSLFVSWKLCWIPWRERGLPFGNKDKQESLNYTDTETNDHDYSEDYLGQPTTYPESSMKISHTSPDIPVDAQAGTKENCVHNARMHRQITEPTSSARHNSIRRQLNLSNPDFNIQQVQKQEQLTGIGRIKPELYKQRSVDTDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAINLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFSVPYNDLNARKLHFSVYDFDRFSRHDLIGQVVVDNFLDLADFPRECNIWKDIEYVTNDNVDLGDLMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCEGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQINLSIAVMDYDRVGHNEVIGVCQVGNDAESLGRDHWNEMLSYPRKPIAHWHPLAEVRLFSCFPITIIVKILLYGIRNRMKFYKQNQDPEVYTKS", "length": 528, "header": "tr|A0A8V0ZQK4-1|A0A8V0ZQK4_CHICK Isoform 1 of Synaptotagmin 9 OS=Gallus gallus OX=9031 GN=SYT9 PE=3 SV=1 CANONICAL=A0A8V0ZQK4-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PWK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4/entry#A0A1D5PWK3-1", "sequence": { "sequence": "MPGDREDEICQKALQLLAELCSVGAVENENCRDFIYYLRDRARPRLTDSDISISLLSLVVTACGLALFGVSLFVSWKLCWIPWRERGLPFGNKDKQESLNYTDTETNDHDYSEDYLGQPTTYPESSMKISHTSPDIPVDAQAGTKENCVHNARMHRQITEPTSSARHNSIRRQLNLSNPDFNIQQVQKQEQLTGIGRIKPELYKQRSVDTDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAINLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFSVPYNDLNARKLHFSVYDFDRFSRHDLIGQVVVDNFLDLADFPRECNIWKDIEYVTNDNVDLGDLMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCEGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQINLSIAVMDYDRVGHNEVIGVCQVGNDAESLGRDHWNEMLSYPRKPIAHWHPLAEESSGGGCPAHPGCAEKYIHSISFWFLNQD", "length": 518, "header": "tr|A0A1D5PWK3-1|A0A8V0ZQK4_CHICK Computationally mapped isoform of Synaptotagmin 9 OS=Gallus gallus OX=9031 GN=SYT9 PE=3 SV=1 CANONICAL=A0A8V0ZQK4-1" }, "locus": { "chromosome": "5", "start_pos": 6909304, "end_pos": 6849914, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051964.1", "url": "https://www.ensembl.org/id/ENSGALT00010051964.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031014.1", "url": "https://www.ensembl.org/id/ENSGALP00010031014.1" } ] } }, { "isoform_ac": "A0A8V0ZJQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4/entry#A0A8V0ZJQ6-1", "sequence": { "sequence": "MPGDREDEICQKALQLLAELCSVGAVENENCRDFIYYLRDRARPRLTDSDISISLLSLVVTACGLALFGVSLFVSWKLCWIPWRERGLPFGNKDKQESLNYTDTETNDHDYSEDYLGQPTTYPESSMKISHTSPDIPVDAQAGTKENCVHNARMHRQITEPTSSARHNSIRRQLNLSNPDFNIQQVQKQEQLTGIGRIKPELYKQRSVDTDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAINLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFSVPYNDLNARKLHFSVYDFDRFSRHDLIGQVVVDNFLDLADFPRECNIWKDIEYVTNDNVDLGDLMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCEGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQINLSIAVMDYDRVGHNEVIGVCQVGNDAESLGRDHWNEMLSYPRKPIAHWHPLAEGPIQQKCYAGLLRLDGCRRGFLTLLTYSAEIWHSC", "length": 524, "header": "tr|A0A8V0ZJQ6-1|A0A8V0ZQK4_CHICK Computationally mapped isoform of Synaptotagmin 9 OS=Gallus gallus OX=9031 GN=SYT9 PE=3 SV=1 CANONICAL=A0A8V0ZQK4-1" }, "locus": { "chromosome": "5", "start_pos": 6908105, "end_pos": 6849914, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051966.1", "url": "https://www.ensembl.org/id/ENSGALT00010051966.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031016.1", "url": "https://www.ensembl.org/id/ENSGALP00010031016.1" } ] } }, { "isoform_ac": "A0A8V0ZQK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4/entry#A0A8V0ZQK4-1", "sequence": { "sequence": "MPGDREDEICQKALQLLAELCSVGAVENENCRDFIYYLRDRARPRLTDSDISISLLSLVVTACGLALFGVSLFVSWKLCWIPWRERGLPFGNKDKQESLNYTDTETNDHDYSEDYLGQPTTYPESSMKISHTSPDIPVDAQAGTKENCVHNARMHRQITEPTSSARHNSIRRQLNLSNPDFNIQQVQKQEQLTGIGRIKPELYKQRSVDTDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAINLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFSVPYNDLNARKLHFSVYDFDRFSRHDLIGQVVVDNFLDLADFPRECNIWKDIEYVTNDNVDLGDLMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCEGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQINLSIAVMDYDRVGHNEVIGVCQVGNDAESLGRDHWNEMLSYPRKPIAHWHPLAEVRLFSCFPITIIVKILLYGIRNRMKFYKQNQDPEVYTKS", "length": 528, "header": "tr|A0A8V0ZQK4-1|A0A8V0ZQK4_CHICK Isoform 1 of Synaptotagmin 9 OS=Gallus gallus OX=9031 GN=SYT9 PE=3 SV=1 CANONICAL=A0A8V0ZQK4-1" }, "locus": { "chromosome": "5", "start_pos": 6907501, "end_pos": 6849914, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051963.1", "url": "https://www.ensembl.org/id/ENSGALT00010051963.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031013.1", "url": "https://www.ensembl.org/id/ENSGALP00010031013.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423026", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423026", "resource": "KEGG Pathway" }, { "id": "R-GGA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TRZ5-1", "protein_name": "Synaptotagmin 9", "gene_name": "SYT9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRTRPRLRDPDISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLFSSSKDNNQEPLNYTDTETNEQENSEGFLDPPTPCPDSSMKISHTSPDIPLSTQTGDQDNCAHGIRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKSCGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLAARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLAEKR", "length": 491 }, "evidence": [ { "id": "A0A8V0ZQK4", "url": "https://omabrowser.org/oma/group/A0A8V0ZQK4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RNF4-1", "protein_name": "Synaptotagmin 9", "gene_name": "SYT9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLFSGSKDNNQEPLNDTDTETNEQENSEGLPDPPTPCPDSSMKISHTSPDIPLSTQPGDQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSHPEFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSHSKACGRLNFMLKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPLPYNDLAARKLHFSVYDFDRFSRHDLIGQVVVEHFLDLADFPRECVLWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITVIKARNLKAMDITGASDPYVKVSLMCEGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNDAERLGRDHWSEMLSYPRKPIAHWHALVEKR", "length": 491 }, "evidence": [ { "id": "A0A8V0ZQK4", "url": "https://omabrowser.org/oma/group/A0A8V0ZQK4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86SS6-1", "protein_name": "Synaptotagmin-9", "gene_name": "SYT9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPTPCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVEKR", "length": 491 }, "evidence": [ { "id": "A0A8V0ZQK4", "url": "https://omabrowser.org/oma/group/A0A8V0ZQK4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q925C0-1", "protein_name": "Synaptotagmin-9", "gene_name": "Syt9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLFSGSKDNNQEPLNYTDTETNEQENSEDFLDPPTPCPDSSMKISHTSPDIPLSTQPGGQDNCAHAVRVQRQVTEPTPSARHNSIRRQLNLSNPDFNIQQLQRQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVHYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFFDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAVMDYDRVGHNEVIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLLEKR", "length": 491 }, "evidence": [ { "id": "A0A8V0ZQK4", "url": "https://omabrowser.org/oma/group/A0A8V0ZQK4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9R0N9-1", "protein_name": "Synaptotagmin-9", "gene_name": "Syt9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLFSGSKDNNQEPLNYTDTETNEQENSEDFLDPPTPCPDSSMKISHTSPDIPLSTQPGGQENCAHAVRVQRQVTEPTPSARHNSIRRQLNLSNPDFNIQQLQRQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVHYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFFDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPESIDQIHLSIAVMDYDRVGHNEVIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLMEKR", "length": 491 }, "evidence": [ { "id": "A0A8V0ZQK4", "url": "https://omabrowser.org/oma/group/A0A8V0ZQK4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "transport vesicle membrane", "id": "GO:0030658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030658", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "dense core granule", "id": "GO:0031045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "positive regulation of vesicle fusion", "id": "GO:0031340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031340", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "regulation of calcium ion-dependent exocytosis", "id": "GO:0017158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" }, { "name": "calcium-dependent activation of synaptic vesicle fusion", "id": "GO:0099502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099502", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQK4" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 220, "end_pos": 341, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 175, "end_pos": 177 }, { "start_pos": 436, "end_pos": 438 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZN64-1", "uniprot_ac": "A0A8V0ZN64", "uniprot_id": "A0A8V0ZN64_CHICK", "mass": { "chemical_mass": 63056.0, "monoisotopic_mass": 63056.0 }, "refseq": { "ac": "XP_046774287", "name": "kelch repeat and BTB domain-containing protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046774287" }, "gene_names": [ { "name": "KBTBD4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZN64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN64" } ] }, { "name": "KBTBD4", "type": "synonym", "evidence": [ { "id": "XP_046774287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046774287" } ] } ], "protein_names": [ { "name": "Kelch repeat and BTB domain containing 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZN64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN64/entry#names_and_taxonomy" } ] }, { "name": "kelch repeat and BTB domain-containing protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046774287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046774287" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046774287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046774287" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN64" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KBTBD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN64", "locus": { "chromosome": "5", "start_pos": 22333790, "end_pos": 22319650, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022032", "url": "https://www.ensembl.org/id/ENSGALG00010022032" } ] } } ], "crossref": [ { "id": "A0A8V0ZN64", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZN64", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008089", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008089", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18272", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18272", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18481", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18481", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423180", "url": "https://www.ncbi.nlm.nih.gov/gene/423180", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011498", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011498", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042950", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042950", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423180", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423180", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYVKPYV", "url": "https://omabrowser.org/oma/group/CYVKPYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RKD0", "url": "https://www.orthodb.org/?gene=A0A1L1RKD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN64", "url": "https://www.orthodb.org/?gene=A0A8V0ZN64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN68", "url": "https://www.orthodb.org/?gene=A0A8V0ZN68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C081", "url": "https://www.orthodb.org/?gene=E1C081", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47195", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47195", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47195:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47195:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E1C081", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E1C081", "database": "PRO", "categories": [ "Protein" ] }, { "id": "XP_046774287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046774287", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1L1RKD0", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RKD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C081", "url": "https://www.uniprot.org/uniprotkb/E1C081", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C081-1", "url": "https://www.uniprot.org/uniprotkb/E1C081-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAAYQYAWFPLYPEGLHNVVSGGRKPFNHDFTDCWRSDLCGTMDSSEETGGSSAEENYFVNYTFTDRSHSGRVAQGIMKLCLEDELFADVTISVEGKEFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIELQDVSESVFQLLVDYIYHGTVKLRAEELQETYEVADMYQLTALFEECSRFLARTVQVRNCLQVMWLADQHSDMGLYTAAKHCAKSHLSQLQDTEEFLHLPLRLLTDILTDGVPCSQNPTAAIETWINFNKEERAGFSETLRSSLKVIGENVHIYLIGKESSRTHSLAVSLHCADDDSISVSGQNSLCHQITAACKHGSDLYVVGGSIPRRMWKCNNATIDWEWCAPLPRDRLQHTLVSVPSKDAIYSLGGKTLQDTLSNAVIYYRVRDNVWTETSQLEVAVSGAAGVNLNGVIYLLGGEENDLDFFTKPSRLIQCYDTNTEKCHVKPYVLPFAGRMHAAVHKDVVFIVAEGDSLLCYNPLLDSFTRLCLPDAWSSVPSLWKIASCNGSIYVFRDRYKKGDANTFKLNPATSVVTVTSGIKVLLTNLQFVLA", "length": 562, "header": "tr|A0A8V0ZN64-1|A0A8V0ZN64_CHICK Isoform 1 of Kelch repeat and BTB domain containing 4 OS=Gallus gallus OX=9031 GN=KBTBD4 PE=4 SV=1 CANONICAL=A0A8V0ZN64-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RKD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN64/entry#A0A1L1RKD0-1", "sequence": { "sequence": "MKGGAADCWRSDLCGTMDSSEETGGSSAEENYFVNYTFTDRSHSGRVAQGIMKLCLEDELFADVTISVEGKEFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIELQDVSESVFQLLVDYIYHGTVKLRAEELQETYEVADMYQLTALFEECSRFLARTVQVRNCLQVMWLADQHSDMGLYTAAKHCAKSHLSQLQDTEEFLHLPLRLLTDILTDGVPCSQNPTAAIETWINFNKEERAGFSETLRSSLKVIGENVHIYLIGKESSRTHSLAVSLHCADDDSISVSGQNSLCHQITAACKHGSDLYVVGGSIPRRMWKCNNATIDWEWCAPLPRDRLQHTLVSVPSKDAIYSLGGKTLQDTLSNAVIYYRVRDNVWTETSQLEVAVSGAAGVNLNGVIYLLGGEENDLDFFTKPSRLIQCYDTNTEKCHVKPYVLPFAGRMHAAVHKDVVFIVAEGDSLLCYNPLLDSFTRLCLPDAWSSVPSLWKIASCNGSIYVFRDRYKKGDANTFKLNPATSVVTVTSGIKVLLTNLQFVLA", "length": 535, "header": "tr|A0A1L1RKD0-1|A0A8V0ZN64_CHICK Computationally mapped isoform of Kelch repeat and BTB domain containing 4 OS=Gallus gallus OX=9031 GN=KBTBD4 PE=4 SV=2 CANONICAL=A0A8V0ZN64-1" }, "locus": { "chromosome": "5", "start_pos": 22333020, "end_pos": 22326833, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053554.1", "url": "https://www.ensembl.org/id/ENSGALT00010053554.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032269.1", "url": "https://www.ensembl.org/id/ENSGALP00010032269.1" } ] } }, { "isoform_ac": "A0A8V0ZN64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN64/entry#A0A8V0ZN64-1", "sequence": { "sequence": "MLAAYQYAWFPLYPEGLHNVVSGGRKPFNHDFTDCWRSDLCGTMDSSEETGGSSAEENYFVNYTFTDRSHSGRVAQGIMKLCLEDELFADVTISVEGKEFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIELQDVSESVFQLLVDYIYHGTVKLRAEELQETYEVADMYQLTALFEECSRFLARTVQVRNCLQVMWLADQHSDMGLYTAAKHCAKSHLSQLQDTEEFLHLPLRLLTDILTDGVPCSQNPTAAIETWINFNKEERAGFSETLRSSLKVIGENVHIYLIGKESSRTHSLAVSLHCADDDSISVSGQNSLCHQITAACKHGSDLYVVGGSIPRRMWKCNNATIDWEWCAPLPRDRLQHTLVSVPSKDAIYSLGGKTLQDTLSNAVIYYRVRDNVWTETSQLEVAVSGAAGVNLNGVIYLLGGEENDLDFFTKPSRLIQCYDTNTEKCHVKPYVLPFAGRMHAAVHKDVVFIVAEGDSLLCYNPLLDSFTRLCLPDAWSSVPSLWKIASCNGSIYVFRDRYKKGDANTFKLNPATSVVTVTSGIKVLLTNLQFVLA", "length": 562, "header": "tr|A0A8V0ZN64-1|A0A8V0ZN64_CHICK Isoform 1 of Kelch repeat and BTB domain containing 4 OS=Gallus gallus OX=9031 GN=KBTBD4 PE=4 SV=1 CANONICAL=A0A8V0ZN64-1" }, "locus": { "chromosome": "5", "start_pos": 22333020, "end_pos": 22328253, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053542.1", "url": "https://www.ensembl.org/id/ENSGALT00010053542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032259.1", "url": "https://www.ensembl.org/id/ENSGALP00010032259.1" } ] } }, { "isoform_ac": "A0A8V0ZN68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN64/entry#A0A8V0ZN68-1", "sequence": { "sequence": "MFEDCWRSDLCGTMDSSEETGGSSAEENYFVNYTFTDRSHSGRVAQGIMKLCLEDELFADVTISVEGKEFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIELQDVSESVFQLLVDYIYHGTVKLRAEELQETYEVADMYQLTALFEECSRFLARTVQVRNCLQVMWLADQHSDMGLYTAAKHCAKSHLSQLQDTEEFLHLPLRLLTDILTDGVPCSQNPTAAIETWINFNKEERAGFSETLRSSLKVIGENVHIYLIGKESSRTHSLAVSLHCADDDSISVSGQNSLCHQITAACKHGSDLYVVGGSIPRRMWKCNNATIDWEWCAPLPRDRLQHTLVSVPSKDAIYSLGGKTLQDTLSNAVIYYRVRDNVWTETSQLEVAVSGAAGVNLNGVIYLLGGEENDLDFFTKPSRLIQCYDTNTEKCHVKPYVLPFAGRMHAAVHKDVVFIVAEGDSLLCYNPLLDSFTRLCLPDAWSSVPSLWKIASCNGSIYVFRDRYKKGDANTFKLNPATSVVTVTSGIKVLLTNLQFVLA", "length": 532, "header": "tr|A0A8V0ZN68-1|A0A8V0ZN68_CHICK Computationally mapped isoform of Kelch repeat and BTB domain containing 4 OS=Gallus gallus OX=9031 GN=KBTBD4 PE=4 SV=1 CANONICAL=A0A8V0ZN64-1" }, "locus": { "chromosome": "5", "start_pos": 22333020, "end_pos": 22327465, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053548.1", "url": "https://www.ensembl.org/id/ENSGALT00010053548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032264.1", "url": "https://www.ensembl.org/id/ENSGALP00010032264.1" } ] } }, { "isoform_ac": "E1C081-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN64/entry#E1C081-1", "sequence": { "sequence": "MRLCNRLSPGIICLDCWRSDLCGTMDSSEETGGSSAEENYFVNYTFTDRSHSGRVAQGIMKLCLEDELFADVTISVEGKEFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIELQDVSESVFQLLVDYIYHGTVKLRAEELQETYEVADMYQLTALFEECSRFLARTVQVRNCLQVMWLADQHSDMGLYTAAKHCAKSHLSQLQDTEEFLHLPLRLLTDILTDGVPCSQNPTAAIETWINFNKEERAGFSETLRSSLKVIGENVHIYLIGKESSRTHSLAVSLHCADDDSISVSGQNSLCHQITAACKHGSDLYVVGGSIPRRMWKCNNATIDWEWCAPLPRDRLQHTLVSVPSKDAIYSLGGKTLQDTLSNAVIYYRVRDNVWTETSQLEVAVSGAAGVNLNGVIYLLGGEENDLDFFTKPSRLIQCYDTNTEKCHVKPYVLPFAGRMHAAVHKDVVFIVAEGDSLLCYNPLLDSFTRLCLPDAWSSVPSLWKIASCNGSIYVFRDRYKKGDANTFKLNPATSVVTVTSGIKVLLTNLQFVLA", "length": 543, "header": "tr|E1C081-1|A0A8V0ZN64_CHICK Computationally mapped isoform of Kelch repeat and BTB domain containing 4 OS=Gallus gallus OX=9031 GN=KBTBD4 PE=4 SV=4 CANONICAL=A0A8V0ZN64-1" }, "locus": { "chromosome": "5", "start_pos": 22333020, "end_pos": 22319849, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053562.1", "url": "https://www.ensembl.org/id/ENSGALT00010053562.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032275.1", "url": "https://www.ensembl.org/id/ENSGALP00010032275.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423180", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423180", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K102-1", "protein_name": "Kelch repeat and BTB domain containing 4", "gene_name": "Kbtbd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFLVPPAGDGWALSGFFKNSLERVDSWQKEKLATMESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRADELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLADRHSDPELYTAAKHCAKTHLAQLQSTEEFLHLPHHLLTDIISDGVPCSQNPTEAIDAWINFNKEEREAFAESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRRMWKCNNATVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLGGEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAPSLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA", "length": 553 }, "evidence": [ { "id": "A0A8V0ZN64", "url": "https://omabrowser.org/oma/group/A0A8V0ZN64/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8W4FEQ2-1", "protein_name": "Kelch repeat and BTB domain containing 4", "gene_name": "KBTBD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLADRHSDPELYTAAKHCAKAHLAQLQNTEEFLHLPHHLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFSESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRRMWKCNNATVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLGGEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSVPSLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA", "length": 518 }, "evidence": [ { "id": "A0A8V0ZN64", "url": "https://omabrowser.org/oma/group/A0A8V0ZN64/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GYL2-1", "protein_name": "Kelch repeat and BTB domain-containing protein 4 isoform X3", "gene_name": "Kbtbd4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLADRHSDPELYTAAKHCAKTHLAQLQSTEEFLHLPHHLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFAESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRRMWKCNNATVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLGGEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAPSLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA", "length": 518 }, "evidence": [ { "id": "A0A8V0ZN64", "url": "https://omabrowser.org/oma/group/A0A8V0ZN64/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8R179-1", "protein_name": "Kelch repeat and BTB domain-containing protein 4", "gene_name": "Kbtbd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGGIADSWQREKLATMESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRADELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLADRHSDPELYTAAKHCAKTHLAQLQSTEEFLHLPHHLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFAESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRRMWKCNNATVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLGGEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAPSLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA", "length": 534 }, "evidence": [ { "id": "A0A8V0ZN64", "url": "https://omabrowser.org/oma/group/A0A8V0ZN64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVX7-2", "protein_name": "Kelch repeat and BTB domain-containing protein 4", "gene_name": "KBTBD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGGNADSWQREKLASMESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLADRHSDPELYTAAKHCAKTHLAQLQNTEEFLHLPHRLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFAESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRRMWKCNNATVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLGGEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAPSLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA", "length": 534 }, "evidence": [ { "id": "A0A8V0ZN64", "url": "https://omabrowser.org/oma/group/A0A8V0ZN64/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZN64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN64" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 156, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 347, "end_pos": 349 }, { "start_pos": 517, "end_pos": 519 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQR1-1", "uniprot_ac": "A0A8V0ZQR1", "uniprot_id": "A0A8V0ZQR1_CHICK", "mass": { "chemical_mass": 46612.0, "monoisotopic_mass": 46612.0 }, "refseq": {}, "gene_names": [ { "name": "SMARCE1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR1" } ] } ], "protein_names": [ { "name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR1/entry#names_and_taxonomy" } ] }, { "name": "BRG1-associated factor 57", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMARCE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR1", "locus": { "chromosome": "27", "start_pos": 4482632, "end_pos": 4497847, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022547", "url": "https://www.ensembl.org/id/ENSGALG00010022547" } ] } } ], "crossref": [ { "id": "A0A8V0ZQR1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000003882", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000003882", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21983", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21983", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420047", "url": "https://www.ncbi.nlm.nih.gov/gene/420047", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A1L1RRC3", "url": "https://www.orthodb.org/?gene=A0A1L1RRC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQR1", "url": "https://www.orthodb.org/?gene=A0A8V0ZQR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWE4", "url": "https://www.orthodb.org/?gene=A0A8V0ZWE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NCC9", "url": "https://www.orthodb.org/?gene=F1NCC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46232:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46232:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3214858", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3214858", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9933937", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933937", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9933939", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933939", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9933946", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933946", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9934037", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9934037", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1L1RRC3", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1L1RRC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RRC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NCC9", "url": "https://www.uniprot.org/uniprotkb/F1NCC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NCC9-1", "url": "https://www.uniprot.org/uniprotkb/F1NCC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTESFNNELKRLCSLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQNNTAAEEEQAANKMEEKKEEESTPMETEPHPEESTENQQNGEEGTSTPDDKESGQEGADSTAEEGTSDSNTGSESNSATVEEPPADPNTEESEKKE", "length": 411, "header": "tr|A0A8V0ZQR1-1|A0A8V0ZQR1_CHICK Isoform 1 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Gallus gallus OX=9031 GN=SMARCE1 PE=1 SV=1 CANONICAL=A0A8V0ZQR1-1" }, "isoforms": [ { "isoform_ac": "A0A1L1RRC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR1/entry#A0A1L1RRC3-1", "sequence": { "sequence": "MSKRPSYAPPPTPAPATASSGITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTESFNNELKRLCSLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQNNTAAEEEQAANKMEEKKEEESTPMETEEPHPEESTENQQNGEEGTSTPDDKESGQEGADSTAEEGTSDSNTGSESNSATVEEPPADPNTEESEKKE", "length": 377, "header": "tr|A0A1L1RRC3-1|A0A8V0ZQR1_CHICK Computationally mapped isoform of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Gallus gallus OX=9031 GN=SMARCE1 PE=1 SV=2 CANONICAL=A0A8V0ZQR1-1" }, "locus": { "chromosome": "27", "start_pos": 4496378, "end_pos": 4483906, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054879.1", "url": "https://www.ensembl.org/id/ENSGALT00010054879.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033177.1", "url": "https://www.ensembl.org/id/ENSGALP00010033177.1" } ] } }, { "isoform_ac": "A0A8V0ZQR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR1/entry#A0A8V0ZQR1-1", "sequence": { "sequence": "MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTESFNNELKRLCSLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQNNTAAEEEQAANKMEEKKEEESTPMETEPHPEESTENQQNGEEGTSTPDDKESGQEGADSTAEEGTSDSNTGSESNSATVEEPPADPNTEESEKKE", "length": 411, "header": "tr|A0A8V0ZQR1-1|A0A8V0ZQR1_CHICK Isoform 1 of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Gallus gallus OX=9031 GN=SMARCE1 PE=1 SV=1 CANONICAL=A0A8V0ZQR1-1" }, "locus": { "chromosome": "27", "start_pos": 4496378, "end_pos": 4483906, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054874.1", "url": "https://www.ensembl.org/id/ENSGALT00010054874.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033172.1", "url": "https://www.ensembl.org/id/ENSGALP00010033172.1" } ] } }, { "isoform_ac": "A0A8V0ZWE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR1/entry#A0A8V0ZWE4-1", "sequence": { "sequence": "MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTESFNNELKRLCSLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQNNTAAEEEQAANKMEEKKEEESTPMETENQQNGEEGTSTPDDKESGQEGADSTAEEGTSDSNTGSESNSATVEEPPADPNTEESEKKE", "length": 403, "header": "tr|A0A8V0ZWE4-1|A0A8V0ZQR1_CHICK Computationally mapped isoform of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Gallus gallus OX=9031 GN=SMARCE1 PE=1 SV=1 CANONICAL=A0A8V0ZQR1-1" }, "locus": { "chromosome": "27", "start_pos": 4496378, "end_pos": 4483906, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054881.1", "url": "https://www.ensembl.org/id/ENSGALT00010054881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033179.1", "url": "https://www.ensembl.org/id/ENSGALP00010033179.1" } ] } }, { "isoform_ac": "F1NCC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR1/entry#F1NCC9-1", "sequence": { "sequence": "MPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTESFNNELKRLCSLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQNNTAAEEEQAANKMEEKKEEESTPMETEEPHPEESTENQQNGEEGTSTPDDKESGQEGADSTAEEGTSDSNTGSESNSATVEEPPADPNTEESEKKE", "length": 394, "header": "tr|F1NCC9-1|A0A8V0ZQR1_CHICK Computationally mapped isoform of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Gallus gallus OX=9031 GN=SMARCE1 PE=1 SV=2 CANONICAL=A0A8V0ZQR1-1" }, "locus": { "chromosome": "27", "start_pos": 4493034, "end_pos": 4483906, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054865.1", "url": "https://www.ensembl.org/id/ENSGALT00010054865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033164.1", "url": "https://www.ensembl.org/id/ENSGALP00010033164.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 12, "start_aa": "Thr", "end_pos": 12, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr12", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-3214858", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3214858", "resource": "Reactome", "description": "RMTs methylate histone arginines" }, { "id": "R-GGA-8939243", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8939243", "resource": "Reactome", "description": "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" }, { "id": "R-GGA-9933937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933937", "resource": "Reactome", "description": "Formation of the canonical BAF (cBAF) complex" }, { "id": "R-GGA-9933939", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9933939", "resource": "Reactome", "description": "Formation of the polybromo-BAF (pBAF) complex" }, { "id": "R-GGA-9933946", "name": 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preliminary review. The reference sequence was derived from JAENSK010000214.1. 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{ "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423255", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423255", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VWAIRAK", "url": "https://omabrowser.org/oma/group/VWAIRAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TY68", "url": "https://www.orthodb.org/?gene=A0A3Q2TY68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPU5", "url": "https://www.orthodb.org/?gene=A0A8V0ZPU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15711:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15711:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11881", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11881", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186619", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186619", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3Q2TY68", 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"MTSLKRSQTERAVATGVSVGTDGTTKVHSDDFYMRRFRSQNGSLGSAVMAPVGPPRNESSHHVTSTPGVPKMGVRARIADWPPRKENIKETSRSSQDIETASCLDSMSSKSSPGSQGSSVNLNASDSVMLKSIQNTLKSKTRQSENLDSRFLTPDGYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTFKSGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDEKSDQRSPGTTKLSELLIASGSKGSGFSLDVIDGPITQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEGELGKSSDLEDNRSEDSVKPWTCPKCFAHYDVQSILFDLNEAAINRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFNSPMGSTEDLNSKGSLNMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKENLILHLDRVKRYIVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPEEIKENGPQYNYRIIFRTSELMTLRGSVLEDAIPSTAKHCTARGLPLKEVLEYVVPELNIHCLRLAFNTPKVTEQLMKLDEQGLSYQLKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRVHGPCTDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAEIYSSGAIVWSVHAKDYSKGMEIDCLLGVSNEFVVLIEQDTKSVVFNCSCRDVIGWTSTDTNIKIFYERGECVSLESFISNIDDIKEIVKRLELVTKGCETVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIVPPYEDCTPRRSCSENYRMPVMEYKVNEGMSYEFKFPFRNNNKWQRNANKGQGPHVAQVPSQVQSPVPSRIGSGKGEGKMPPPERAANIPRSISSDGRPLESRRLSPGSDVYVTVSSIALARSQQCRNSPSNLSTSSETGSAGSTYRQKSMPEGFGISRRSPASIDRQSTQSDTGGSGKSTPSWQRSEDSIADQMEPTCHLPAVSKVLPSFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDSGERTEAELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSPRTGLTKEKVTPLWHSSSEVVSIADRTLEKESHIDRKAESSLSLDIHSKSQPASNPLTRENSAYSLSDAVSHTSTMSSRHSASPVVFTSARSSPKEELHSATSPQLAPSFSSSSSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEMAHPRLRASARDLRASPKRASKSTVEEDLKKLIDLDSPTPESQKNFKSHTLSCQSPFPSTPTTRRALQRTLSDESIYSGQRDHFFASRASLLDQAMPNDVLFTSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQEQRRQPMPDPGLMPLPDSASDLDWSNLVDAAKAFEVQRASFFAVADENHRPVSAASSGDQAEDQLTAQIKPYTGKESPPTLASKVDQLEGLLKMLQEDLRKEKEDKANLQAEVQHLREDNLRLQEESQNATEKLKKFTEWVFNTIDMN", "length": 1785, "header": "tr|A0A8V0ZPU5-1|A0A8V0ZPU5_CHICK Isoform 1 of Signal induced proliferation associated 1 like 1 OS=Gallus gallus OX=9031 GN=SIPA1L1 PE=1 SV=1 CANONICAL=A0A8V0ZPU5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TY68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5/entry#A0A3Q2TY68-1", "sequence": { "sequence": "MYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRVHGPCTDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAEIYSSGAIVWSVHAKDYSKGMEIDCLLGVSNEFVVLIEQDTKSVVFNCSCRDVIGWTSTDTNIKIFYERGECVSLESFISNIDDIKEIVKRLELVTKGCETVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIVPPYEDCTPRRSCSENYRMPVMEYKVNEGMSYEFKFPFRNNNKWQRNANKGQGPHVAQVPSQVQSPVPSRIGSGKGEGKMPPPERAANIPRSISSDGRPLESRRLSPGSDVYVTVSSIALARSQQCRNSPSNLSTSSETGSAGSTYRQKSMPEGFGISRRSPASIDRQSTQSDTGGSGKSTPSWQRSEDSIADQMEPTCHLPAVSKVLPSFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDSGERTEAELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSPRTGLTKEKVTPLWHSSSEVVSIADRTLEKESHIDRKAESSLSLDIHSKSQPASNPLTRENSAYSLSDAVSHTSTMSSRHSASPVVFTSARSSPKEELHSATSPQLAPSFSSSSSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEMAHPRLRASARDLRASPKRASKSTVEEDLKKLIDLDSPTPESQKNFKSHTLSCQSPFPSTPTTRRALQRTLSDESIYSGQRDHFFASRASLLDQAMPNDVLFTSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQEQRRQPMPDPGLMPLPDSASDLDWSNLVDAAKAFEVQRASFFAVADENHRPVSAASSGDQAEDQLTAQIKPYTGKESPPTLASKVDQLEGLLKMLQEDLRKEKEDKANLQAEVQHLREDNLRLQEESQNATEKLKKFTEWVFNTIDMN", "length": 1170, "header": "tr|A0A3Q2TY68-1|A0A8V0ZPU5_CHICK Computationally mapped isoform of Signal induced proliferation associated 1 like 1 OS=Gallus gallus OX=9031 GN=SIPA1L1 PE=1 SV=1 CANONICAL=A0A8V0ZPU5-1" }, "locus": { "chromosome": "5", "start_pos": 26530755, "end_pos": 26476959, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051557.1", "url": "https://www.ensembl.org/id/ENSGALT00010051557.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030748.1", "url": "https://www.ensembl.org/id/ENSGALP00010030748.1" } ] } }, { "isoform_ac": "A0A8V0ZPU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5/entry#A0A8V0ZPU5-1", "sequence": { "sequence": "MTSLKRSQTERAVATGVSVGTDGTTKVHSDDFYMRRFRSQNGSLGSAVMAPVGPPRNESSHHVTSTPGVPKMGVRARIADWPPRKENIKETSRSSQDIETASCLDSMSSKSSPGSQGSSVNLNASDSVMLKSIQNTLKSKTRQSENLDSRFLTPDGYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTFKSGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDEKSDQRSPGTTKLSELLIASGSKGSGFSLDVIDGPITQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEGELGKSSDLEDNRSEDSVKPWTCPKCFAHYDVQSILFDLNEAAINRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFNSPMGSTEDLNSKGSLNMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKENLILHLDRVKRYIVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPEEIKENGPQYNYRIIFRTSELMTLRGSVLEDAIPSTAKHCTARGLPLKEVLEYVVPELNIHCLRLAFNTPKVTEQLMKLDEQGLSYQLKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRVHGPCTDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAEIYSSGAIVWSVHAKDYSKGMEIDCLLGVSNEFVVLIEQDTKSVVFNCSCRDVIGWTSTDTNIKIFYERGECVSLESFISNIDDIKEIVKRLELVTKGCETVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIVPPYEDCTPRRSCSENYRMPVMEYKVNEGMSYEFKFPFRNNNKWQRNANKGQGPHVAQVPSQVQSPVPSRIGSGKGEGKMPPPERAANIPRSISSDGRPLESRRLSPGSDVYVTVSSIALARSQQCRNSPSNLSTSSETGSAGSTYRQKSMPEGFGISRRSPASIDRQSTQSDTGGSGKSTPSWQRSEDSIADQMEPTCHLPAVSKVLPSFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDSGERTEAELNSYNYLQGTSADSGIDTTSYGPSHGSTASLGAATSPRTGLTKEKVTPLWHSSSEVVSIADRTLEKESHIDRKAESSLSLDIHSKSQPASNPLTRENSAYSLSDAVSHTSTMSSRHSASPVVFTSARSSPKEELHSATSPQLAPSFSSSSSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEMAHPRLRASARDLRASPKRASKSTVEEDLKKLIDLDSPTPESQKNFKSHTLSCQSPFPSTPTTRRALQRTLSDESIYSGQRDHFFASRASLLDQAMPNDVLFTSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQEQRRQPMPDPGLMPLPDSASDLDWSNLVDAAKAFEVQRASFFAVADENHRPVSAASSGDQAEDQLTAQIKPYTGKESPPTLASKVDQLEGLLKMLQEDLRKEKEDKANLQAEVQHLREDNLRLQEESQNATEKLKKFTEWVFNTIDMN", "length": 1785, "header": "tr|A0A8V0ZPU5-1|A0A8V0ZPU5_CHICK Isoform 1 of Signal induced proliferation associated 1 like 1 OS=Gallus gallus OX=9031 GN=SIPA1L1 PE=1 SV=1 CANONICAL=A0A8V0ZPU5-1" }, "locus": { "chromosome": "5", "start_pos": 26542620, "end_pos": 26476959, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051563.1", "url": "https://www.ensembl.org/id/ENSGALT00010051563.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030753.1", "url": "https://www.ensembl.org/id/ENSGALP00010030753.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 756, "start_aa": "Thr", "end_pos": 756, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr756", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423255", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423255", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M3G5-1", "protein_name": "Signal induced proliferation associated 1 like 1", "gene_name": "SIPA1L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTSLKRSQTERPVATERASIVGADGTPKVHTDDFYMRRFRSQNGSLGSSVMAPVGPPRSEGSHHITSTPGVPKMGVRARIADWPPRKENVKESSRSSQEIETSSCLESMSSKSSPVSQGSSVSLNSSDSAMLKSIQNTLKSKTRPSENMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKTGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDKSDRGPSPTKLSDFLIAGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLSMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKENLVLHLDRVKRYIVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPEETKENGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVIPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYRDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRVHNPCTDSVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAKDYNKAMEIDCLLGVSSEFIVLIEQETKSVVFNCSCRDVIGWTSTDASLKIFYERGECVSVESFVNNDDIKEIVKRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNANKGPHSPQVPSQVQSPMTSRLNAGKADGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQPCRNSPSSLSSSSETGSGGGTYRQKSMPEGFGISRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTEAELNSYNFLQGTSADSGIDTTSYGPSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLEAESHGLDRKTESSLSLDIHTKSQAGSSPLTRENPTFSINDAASHTSTMSSRHSASPVVFTSARSSPKEELHPATPPQLAPSFSSSSSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHPRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPDSQKNFKFHALSSPQSPFPTTPTSRRALHRTLSDESIYSGQREHFFTSRASLLDQALPNDVLFSSTYPSLPTSLPLRRPSYTLGMKSLHGEFSASDSSLTDVQETRRPPMPDPGLMPLPDAAADLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAAASSDQLEDQALVQMKSYSSSKDSSPTLASKVDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKLKKFTEWVFNTIDMS", "length": 1784 }, "evidence": [ { "id": "A0A8V0ZPU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZPU5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2QC75-1", "protein_name": "Signal-induced proliferation-associated 1-like protein 1 isoform X2", "gene_name": "Sipa1l1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTSLKRSQTERPVTADRASVVSTDGTPKVHTDDFYMRRFRSQNGSLGSSVMAAVGPPRSEGPHHITSTPGVPKMGVRARIADWPPRKENVKESSRSSQEIETSSCLESLSSKGSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTGPAENMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKSGPSLHREYGSTSSIDKQGTSGESFFDLLKGYKDDRSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAVVNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLGMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESASFESTLSSHCTNAGVAVLEVPKESLMLHLDRVKRYTVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPEEMKENGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHAIPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRAHNPCTESVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAKDYNKAMEFDCLLGISNEFIVLIDQETRSVAFNCSCRDVIGWTSSDTSLKIFYERGECVSVESFISSEDIKEIVKRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEFKFPFRNNNKWQRNANKGAHSPQVPSQLQSPMTSRLNAGKGDGKMPPPERAGNIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSSSETGSGGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSIADQMEPTCHLPAVSKVLPAFRDSPSGRLIRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGLSHGSTASLGAATSSPRSGPGKEKVAPLWHSSSEVLSLADRTLETEGHGLDRKTESSLSLDLHSKSQGGSSPLTRENSTFSINDAGSHTSTMSSRHSASPVVFSSARSSPKEELHPTTTSQLAPSFSSASSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEMAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKNFKFHALSSPQSPFPPTPTSRRALHRTLSDESIYSGQREHFFASRASLLDQALPNDVLFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPIPDPGLMPLPDTAADLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEEQALVQMKSYSSKESSPTLASKVDQLEGMLKMLREDLKKEKEDKAHLQAEVQHLREDNLRLQEESQNASDKLKKFTEWVFNTIDMS", "length": 1782 }, "evidence": [ { "id": "A0A8V0ZPU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZPU5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O35412-1", "protein_name": "Signal-induced proliferation-associated 1-like protein 1", "gene_name": "Sipa1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSLKRSQTERPVTADRASVVSTDGTPKVHTDDFYMRRFRSQNGSLGSSVMAAVGPPRSEGPHHITSTPGVPKMGVRARIADWPPRKENVKESSRSSQEIETSSCLESLSSKGSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTGPAESMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKSGPSLHREYGSTSSIDKQGTSGESFFGLLKGYKDDRADRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSTSFSSPMGSTEDFNSKGSLGMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESTSFESALSSHCTNAGVAVLEVPKESLMLHLDRVRRYTVEHVDLGAYYYRKCFYQKEHWNYFGADENLGPVAVSIRREKPEDMKENGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVIPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNTPKVTEQFMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRAHNPCTESVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAKDYNKAMEFDCLLGISNEFIVLIEQETKSVVFNCSCRDVIGWTSSDSSLKIFYERGECISVESFMSSEDIKEIVKRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLKQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKMNEGVSYEYKFPFRSNNKWQRNAGKGAHSPQVPLQLQSPMISRVNAGKGDGKMPLPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSSSETGSGGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDIGGSGKSTPSWQRSEDSLADQMEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESDLNSYNYLQGTSADSGIDTASYGLSHGSTASLGASTSSPRSGPGKEKVAPLWHSSSEVLSLADRTLETEGHGMDRKTESSLSLDIHSKSQGGSSPLTRENSTFSINDATSHTSTMSSRHSASPVVFSSARSSPKEELHPTTSSQLAPSFSSSSSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLRASPKPTSKSTIEEDLKKLIDLESPTPESQKNFKFHGLSSPQSPFPSTPTSRRALHRTLSDESIYSSQREHFFTSRASLLDQALPNDVFFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFFASDSSLTDIQETRRQPIPDPGLMPLPDTASDLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEEQALVQMKSYSSSKDSSPTLASKVDQLEGMLKMLREDLKKEKEDKAHLQAEVEHLREDNLRLQEESQNASDKLKKFTEWVFNTIDMS", "length": 1822 }, "evidence": [ { "id": "A0A8V0ZPU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZPU5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43166-1", "protein_name": "Signal-induced proliferation-associated 1-like protein 1", "gene_name": "SIPA1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1804 }, "evidence": [ { "id": "A0A8V0ZPU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZPU5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5TYS4-1", "protein_name": "Signal-induced proliferation-associated 1-like protein 1", "gene_name": "sipa1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSLKRSQTERSVGGSVPASDEFYTRRLRLPNGGAPPPRSESTHLTGTPGVPKMGVRARVADWPPRKDGGSGGSGGSGGSSGSGGGGGGGGGGGGNGGGVWHITVETDSPSTTTGSAQSNLSSKLGHLISPQDSSMLRNIHNTLKNKMQSKGKDNRFLSPDGYLGSPRKGMRRIRQRSNSDITISELDGDGSEGWSFSGWTPMHREYGSTSSIDKHGVSGESFFDMLKGYTTDAPDQRSPAPEKLSELLTVAHKQTALDLPDGPLGPPRGSPASRLKEREKQMKRRSKSETGGESIFRKLRSVKAEGDSSRAGSDAEDGKSDDLGPPPKPWVCQKGFAHFDVQSILFDLNEVVQSRQSAAKRKNTTTGASAAAAASASNTSSLSSTQSGAYGSPCGSQEELSVKDGPSLDSGDDKSNDLVLSCPCFRNEIGGEGERNISPSKQGSIGSGASSSSRDEEGSPERAPNTHFSNAGVAVLEAPKDGKSLHHDRGKSNILEHVDLGAYYYRKNFYLREHWNYLGVDETLGPVAVSIRREKLEDHKEHGQQYNYRIIFRTSELTTIRGSILEDAVPSTSKHGLARGLPLKEVLDYLVPELNAHCLRLALNTPKVTEQLMKLDEQGLSFQLKVGVMYCQAGQSSEEEMYNNETAGPALEEFLQLLGERVRLKGFSKYRAQLDTKTDSTGTHSLYTTFKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAKPFSPKNIRSHFQHVFVVVRALNPCTENACYRVAVARSRDVPAFGPPIPEDATFPKSTVFRDFLLAKVINAENAAHKSDKFRAMATRTRQEYLRDLAERHVTSTPIDPSGKFPFISLAHKRKEKTRPYLGAELRSPGAITWPVYAEDHGAGGELEALLAISNDFLVLVDPEAKAVVFNCAVRDVIGWTLGSPASMKIYYERGENISLRSMNNNTEDFREVVKRLEHLTKGCETSEMTLRRNGLGQLGFHVNYEGIVAEVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHEDATPRRGCSELHRMPVVEYKGSNESGSFEYKFPFRSNNNKWQRTSSSPQQSLTASPQSHSGTPNRAVSLGASMGKTLSAERPERAAAIPRSVSSDGRPLDSKRMSPGSENYALTSSLMLGRSQHNRSSPSNLSCSSDTGSGSSAHWRQKSMPEGFAHNRHSPLPPERQMAAEGGSSGKSTPSWPRVEDSSDRPPSDAPVTKSSSSYSGGPRIQRQEQVIHLSPKKGSQSEGPYSHSSSNTLSSTTSSGGHSDDKWYDLGSGGMGDQPESEPNGLGGGGYLQGASADSGIDTTSYGPTTHGSSSSLLAVGSAGARERAPSPWHSPTDGGRRVLERSPPAAESPVSPADGPPTTRSPPTHLLVRDGSTYSLSDMASYSSNRHSVSPAVMSSSHSSPREESSSATSPSSSSSQSSVSPGPKSFYPRQGATSKYLIGWRKPGSTINSVDFGDTRKRPQGEGTDLGSSQSRPSLRDLHSPQAMCKSTVDDDMKKLIITPESPPSIKHKEKLSSSGPSSSGRRSLHRTLSDESIYRGQRLPSLGDSVLEQALASDVLFSCSTLPRSPTTRGAPLRRPSYKMGIKMHGDLSASDTSLADLHDRQRLPPPELGLMPLPDTDTDSGLDWTHLVDVANAFEGERRPQRMQRGFMFSSQDVSHRGETSLSLQHLDLQPVPHTRLSPSEGPSSYGGKVSQLEALVKMLQEDLKKEREEKLKLQAQIKRLWEDNQRLQEESQSSAAKLKKFTEWVFNTIDLN", "length": 1794 }, "evidence": [ { "id": "A0A8V0ZPU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZPU5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C0T5-1", "protein_name": "Signal-induced proliferation-associated 1-like protein 1", "gene_name": "Sipa1l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKRSQTERPVTADRASVVSTDGAPKVHTDDFYMRRFRSQNGSLGSSVMAAVGPPRSEGPHHITSTPGVPKMGVRARIADWPPRKENVKESSRSSQEIETSSCLESLSSKGSPVSQGSSVSLNSNDSAMLKSIQNTLKNKTGPAESMDSRFLMPEAYPSSPRKALRRIRQRSNSDITISELDVDSFDECISPTYKSGPSLHREYGSTSSIDKQGTSGDSFFDLLKGYKDDRSDRGPTPTKLSDFLITGGGKGSGFSLDVIDGPISQRENLRLFKEREKPLKRRSKSETGDSSIFRKLRNAKGEELGKSSDLEDNRSEDSVRPWTCPKCFAHYDVQSILFDLNEAIMNRHNVIKRRNTTTGASAAAVASLVSGPLSHSASFSSPMGSTEDLNSKGSLGMDQGDDKSNELVMSCPYFRNEIGGEGERKISLSKSNSGSFSGCESTSFESALSSHCTNAGVAVLEVPKESLMLHLDRVKRYTVEHVDLGAYYYRKFFYQKEHWNYFGADENLGPVAVSIRREKPEDMKENGSPYNYRIIFRTSELMTLRGSVLEDAIPSTAKHSTARGLPLKEVLEHVIPELNVQCLRLAFNTPKVTEQLMKLDEQGLNYQQKVGIMYCKAGQSTEEEMYNNESAGPAFEEFLQLLGERVRLKGFEKYRAQLDTKTDSTGTHSLYTTYKDYEIMFHVSTMLPYTPNNKQQLLRKRHIGNDIVTIVFQEPGAQPFSPKNIRSHFQHVFVIVRAHNPCTESVCYSVAVTRSRDVPSFGPPIPKGVTFPKSNVFRDFLLAKVINAENAAHKSEKFRAMATRTRQEYLKDLAEKNVTNTPIDPSGKFPFISLASKKKEKSKPYPGAELSSMGAIVWAVRAKDYNKAMEFDCLLGISSEFIVLIEQETKSVAFNCSCRDVIGWTSSDTSLKIFYERGECVSVESFISGEDIKEIVRRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAGLRQGSRLVEICKVAVATLSHEQMIDLLRTSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYQMNEGISYEFKFPFRNNNKWQRNASKGAHSPQVPSQLQSPMTSRLNAGKGDGKMPPPERAANIPRSISSDGRPLERRLSPGSDIYVTVSSMALARSQCRNSPSNLSSSSETGSGGGTYRQKSMPEGFGVSRRSPASIDRQNTQSDISGSGKSTPSWQRSEDSLADQMEPTCHLPAVSKVLPAFRESPSGRLMRQDPVVHLSPNKQGHSDSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESDLNSYNYLQGTSADSGIDTASYGPSHGSTASLGASTSSPRSGPGKEKVAPLWHSSSEVLSLADRTLETEGHGMDRKAESSLSLDIHSKSQGGSSPLSRENSTFSINDAASHTSTMSSRHSASPVVFSSARSSPKEELHPTASSQLAPSFSSSSSSSSGPRTFYPRQGATSKYLIGWKKPEGTINSVGFMDTRKRHQSDGNEIAHTRLRASTRDLQASPKPTSKSTIEEDLKKLIDLESPTPESQKNFKFHALSSPQSPFPTTPTSRRALHRTLSDESIYSSQREHFFTSRASLLDQALPNDVLFSSTYPSLPKSLPLRRPSYTLGMKSLHGEFSASDSSLTDIQETRRQPIPDPGLMPLPDAASDLDWSNLVDAAKAYEVQRASFFAASDENHRPLSAASNSDQLEEQALVQMKSYSSKDPSPTLASKVDQLEGMLKMLREDLKKEKEDKAQLQAEVEHLREDNLRLQEESQNASDKLKKFTEWVFNTIDMS", "length": 1782 }, "evidence": [ { "id": "A0A8V0ZPU5", "url": "https://omabrowser.org/oma/group/A0A8V0ZPU5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" } ], "pmid": "" }, { "name": "ephrin receptor binding", "id": "GO:0046875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046875", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" } ], "pmid": "" }, { "name": "regulation of axonogenesis", "id": "GO:0050770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" } ], "pmid": "" }, { "name": "ephrin receptor signaling pathway", "id": "GO:0048013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" } ], "pmid": "" }, { "name": "regulation of synaptic plasticity", "id": "GO:0048167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048167", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" } ], "pmid": "" }, { "name": "regulation of dendritic spine morphogenesis", "id": "GO:0061001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061001", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1157, "end_pos": 1159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1277, "end_pos": 1279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1766, "end_pos": 1768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" }, { "start_pos": 898, "end_pos": 900, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 954, "end_pos": 1018, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZPU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU5" }, { "id": "PS50085", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50085" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rap-GAP", "eco_id": "ECO_0000259", "start_pos": 599, "end_pos": 816, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 756 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1157, "end_pos": 1159 }, { "start_pos": 123, "end_pos": 125 }, { "start_pos": 1277, "end_pos": 1279 }, { "start_pos": 1766, "end_pos": 1768 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 57, "end_pos": 59 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 820, "end_pos": 822 }, { "start_pos": 898, "end_pos": 900 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQ32-1", "uniprot_ac": "A0A8V0ZQ32", "uniprot_id": "A0A8V0ZQ32_CHICK", "mass": { "chemical_mass": 88485.0, "monoisotopic_mass": 88485.0 }, "refseq": {}, "gene_names": [ { "name": "OGFR", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32" } ] } ], "protein_names": [ { "name": "Opioid growth factor receptor", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "OGFR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32", "locus": { "chromosome": "20", "start_pos": 8682674, "end_pos": 8671043, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022308", "url": "https://www.ensembl.org/id/ENSGALG00010022308" } ] } } ], "crossref": [ { "id": "A0A8V0ZQ32", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQ32", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005609", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005609", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR006757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2U3T5", "url": "https://www.orthodb.org/?gene=A0A3Q2U3T5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHG9", "url": "https://www.orthodb.org/?gene=A0A8V0ZHG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ32", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14015:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14015:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U3T5", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U3T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U3T5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISWLPFHPTCVGVHVHSCCCSRGVLAVPSTRVLLMEGGKFPLLQQPVPTNNRVARLGRRAKTRVPLRPPYSCLQDGVPSSSRRAEEDEEGDEASFWRYDSTWEEDDDEDEDGDEGQPEGAEAAAGEEPEDSEKSALSSPREPRQAQPRWYDIFQKLLMYLFNTEGQRRSNSSPLFQRSFKFSGRRNWNAAIDLQRYRHRYPGLIESETDEEEDMWNLSFYKNEIAFMPHGLHIEDLLESWWDNYEVLEENHSYIQWLFPLREHGMNFRAKPLTCQEIEALKKSEEVMERFIRAYRLMLRFYGIILVNQETGELERAENWAERFLNLNRFSHNNLRITRILKCLGEMGYEHYQVHLVKFFLTETLVNETLPNVKRSALDYFLFTIRSKRKRRELVHYAWQHYKPQGSFVWGPHDKLLKYRPRSTKSKLHQKAENKQETPGKKIDDSVEEGQNQSPEEEQKVGDTADLQTEANKEDTREKISECVSEGGDDEDDDKTSFAQQEKDCNSEAEVQDAAENDCTKESKKRKLDANIADNIKSGLLKSPSDIEKISSNLEECAIDAEIPSNPLVQTGQDQETPKEENANAKEVTVPETGDAAIKRRKVDKRTQRNKTFNLAINLNMAPPAHSAQSHPSVSNAKTEDEKVGEKKAAVEEMSGKAEGNAIGGALSSSAASVLPSTAQTSPLSDGMELSADQVAARSDEHHCNTTLLESNSEAGGVEQHKNTANVSEKEGAKATDNKQVPGSPEQSFASSCAEQDSAEVAIQRTDSSEHTAEPGEEHIATA", "length": 783, "header": "tr|A0A8V0ZQ32-1|A0A8V0ZQ32_CHICK Isoform 1 of Opioid growth factor receptor OS=Gallus gallus OX=9031 GN=OGFR PE=1 SV=1 CANONICAL=A0A8V0ZQ32-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U3T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32/entry#A0A3Q2U3T5-1", "sequence": { "sequence": "MISWLPFHPTCVGVHVHSCCCSRGVLAVPSTRVLLMEGGKFPLLQQPVPTNNRVARLGRRAKTRVPLRPPYSCLQDGVPSSSRRAEEDEEGDEASFWRYDSTWEEDDDEDEDGDEGQPEGAEAAAGEEPEDSEKSALSSPREPRQAQGQRRSNSSPLFQRSFKFSGRRNWNAAIDLQRYRHRYPGLIESETDEEEDMWNLSFYKNEIAFMPHGLHIEDLLESWWDNYEVLEENHSYIQWLFPLREHGMNFRAKPLTCQEIEALKKSEEVMERFIRAYRLMLRFYGIILVNQETGELERAENWAERFLNLNRFSHNNLRITRILKCLGEMGYEHYQVHLVKFFLTETLVNETLPNVKRSALDYFLFTIRSKRKRRELVHYAWQHYKPQGSFVWGPHDKLLKYRPRSTKSKLHQKAENKQETPGKKIDDSVEEGQNQSPEEEQKVGDTADLQTEANKEDTREKISECVSEGGDDEDDDKTSFAQQEKDCNSEAEVQDAAENDCTKESKKRKLDANIADNIKSGLLKSPSDIEKISSNLEECAIDAEIPSNPLVQTGQDQETPKEENANAKEVTVPETGDAAIKRRKVDKRTQRNKTFNLAINLNMAPPAHSAQSHPSVSNAKTEDEKVGEKKAAVEEMSGKAEGNAIGGALSSSAASVLPSTAQTSPLSDGMELSADQVAARSDEHHCNTTLLESNSEAGGVEQHKNTANVSEKEGAKATDNKQVPGSPEQSFASSCAEQDSAEVAIQRTDSSEHTAEPGEEHIATA", "length": 765, "header": "tr|A0A3Q2U3T5-1|A0A8V0ZQ32_CHICK Computationally mapped isoform of Opioid growth factor receptor OS=Gallus gallus OX=9031 GN=OGFR PE=1 SV=1 CANONICAL=A0A8V0ZQ32-1" }, "locus": { "chromosome": "20", "start_pos": 8680496, "end_pos": 8671242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054275.1", "url": "https://www.ensembl.org/id/ENSGALT00010054275.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032772.1", "url": "https://www.ensembl.org/id/ENSGALP00010032772.1" } ] } }, { "isoform_ac": "A0A8V0ZHG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32/entry#A0A8V0ZHG9-1", "sequence": { "sequence": "MAAWFGFRAEEDEEGDEASFWRYDSTWEEDDDEDEDGDEGQPEGAEAAAGEEPEDSEKSALSSPREPRQAQGQRRSNSSPLFQRSFKFSGRRNWNAAIDLQRYRHRYPGLIESETDEEEDMWNLSFYKNEIAFMPHGLHIEDLLESWWDNYEVLEENHSYIQWLFPLREHGMNFRAKPLTCQEIEALKKSEEVMERFIRAYRLMLRFYGIILVNQETGELERAENWAERFLNLNRFSHNNLRITRILKCLGEMGYEHYQVHLVKFFLTETLVNETLPNVKRSALDYFLFTIRSKRKRRELVHYAWQHYKPQGSFVWGPHDKLLKYRPRSTKSKLHQKAENKQETPGKKIDDSVEEGQNQSPEEEQKVGDTADLQTEANKEDTREKISECVSEGGDDEDDDKTSFAQQEKDCNSEAEVQDAAENDCTKESKKRKLDANIADNIKSGLLKSPSDIEKISSNLEECAIDAEIPSNPLVQTGQDQETPKEENANAKEVTVPETGDAAIKRRKVDKRTQRNKTFNLAINLNMAPPAHSAQSHPSVSNAKTEDEKVGEKKAAVEEMSGKAEGNAIGGALSSSAASVLPSTAQTSPLSDGMELSADQVAARMISQDVFSALRAV", "length": 617, "header": "tr|A0A8V0ZHG9-1|A0A8V0ZQ32_CHICK Computationally mapped isoform of Opioid growth factor receptor OS=Gallus gallus OX=9031 GN=OGFR PE=1 SV=1 CANONICAL=A0A8V0ZQ32-1" }, "locus": { "chromosome": "20", "start_pos": 8682632, "end_pos": 8671712, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054268.1", "url": "https://www.ensembl.org/id/ENSGALT00010054268.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032765.1", "url": "https://www.ensembl.org/id/ENSGALP00010032765.1" } ] } }, { "isoform_ac": "A0A8V0ZQ32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32/entry#A0A8V0ZQ32-1", "sequence": { "sequence": "MISWLPFHPTCVGVHVHSCCCSRGVLAVPSTRVLLMEGGKFPLLQQPVPTNNRVARLGRRAKTRVPLRPPYSCLQDGVPSSSRRAEEDEEGDEASFWRYDSTWEEDDDEDEDGDEGQPEGAEAAAGEEPEDSEKSALSSPREPRQAQPRWYDIFQKLLMYLFNTEGQRRSNSSPLFQRSFKFSGRRNWNAAIDLQRYRHRYPGLIESETDEEEDMWNLSFYKNEIAFMPHGLHIEDLLESWWDNYEVLEENHSYIQWLFPLREHGMNFRAKPLTCQEIEALKKSEEVMERFIRAYRLMLRFYGIILVNQETGELERAENWAERFLNLNRFSHNNLRITRILKCLGEMGYEHYQVHLVKFFLTETLVNETLPNVKRSALDYFLFTIRSKRKRRELVHYAWQHYKPQGSFVWGPHDKLLKYRPRSTKSKLHQKAENKQETPGKKIDDSVEEGQNQSPEEEQKVGDTADLQTEANKEDTREKISECVSEGGDDEDDDKTSFAQQEKDCNSEAEVQDAAENDCTKESKKRKLDANIADNIKSGLLKSPSDIEKISSNLEECAIDAEIPSNPLVQTGQDQETPKEENANAKEVTVPETGDAAIKRRKVDKRTQRNKTFNLAINLNMAPPAHSAQSHPSVSNAKTEDEKVGEKKAAVEEMSGKAEGNAIGGALSSSAASVLPSTAQTSPLSDGMELSADQVAARSDEHHCNTTLLESNSEAGGVEQHKNTANVSEKEGAKATDNKQVPGSPEQSFASSCAEQDSAEVAIQRTDSSEHTAEPGEEHIATA", "length": 783, "header": "tr|A0A8V0ZQ32-1|A0A8V0ZQ32_CHICK Isoform 1 of Opioid growth factor receptor OS=Gallus gallus OX=9031 GN=OGFR PE=1 SV=1 CANONICAL=A0A8V0ZQ32-1" }, "locus": { "chromosome": "20", "start_pos": 8680496, "end_pos": 8671242, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054272.1", "url": "https://www.ensembl.org/id/ENSGALT00010054272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032768.1", "url": "https://www.ensembl.org/id/ENSGALP00010032768.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "opioid growth factor receptor activity", "id": "GO:0140625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ32", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 705, "end_pos": 707, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQ32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ32" }, { "id": "PF04664", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04664" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Opioid growth factor receptor (OGFr) conserved", "eco_id": "ECO_0000259", "start_pos": 211, "end_pos": 416, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 217, "end_pos": 219 }, { "start_pos": 251, "end_pos": 253 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 452, "end_pos": 454 }, { "start_pos": 610, "end_pos": 612 }, { "start_pos": 705, "end_pos": 707 }, { "start_pos": 726, "end_pos": 728 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQZ2-1", "uniprot_ac": "A0A8V0ZQZ2", "uniprot_id": "A0A8V0ZQZ2_CHICK", "mass": { "chemical_mass": 79345.0, "monoisotopic_mass": 79345.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF385C", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2" } ] } ], "protein_names": [ { "name": "Zinc finger protein 385C", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF385C", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZQZ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQZ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000052994", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000052994", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420031", "url": "https://www.ncbi.nlm.nih.gov/gene/420031", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420030", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420030", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HWKEEFP", "url": "https://omabrowser.org/oma/group/HWKEEFP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2UG52", "url": "https://www.orthodb.org/?gene=A0A3Q2UG52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQY7", "url": "https://www.orthodb.org/?gene=A0A8V0ZQY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQZ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZQZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWK5", "url": "https://www.orthodb.org/?gene=A0A8V0ZWK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWK8", "url": "https://www.orthodb.org/?gene=A0A8V0ZWK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23067:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23067:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46880", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46880", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46880:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46880:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2UG52", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2UG52-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQY7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWK8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRPLSPSHSPESGLRLVEVTSCPPGPPEQRTKREKKHQSFTLCEVCNIQLNSAAQAQIHYNGKSHQKRLKQLNKGKMPAAQECRQALVKNKHGKAENAFTVGTDNFQRHALLRHVTSGAHRQALAVNREQMAFEARGHAELRSVLKVEVNPAKVAVLTTVYWMAKEEILDEKCSSLLDLQKFNLCQALLASEHSERYHAGSLRDMQAAMAKVLHNEDRHRIKASPFVGLVVDETVDAMEHRSLAVFSTTVSPCSGQTSATFLGSFELLAGEAATVTGKVGEVLRAFGIPAMKLTWLSAHSASLGAERRSGAGTALSSLCPLLTEMHCLSHGSSLLPTHSSLSIEYLQKYETTVDAIYRLYSSPTGESSGLQELWSVLDLCEIDLGSPRAICWTSIFPAVEAIDSSWPTLVLLLENEAERSPVALGLCQELKKFHFVAFTKILLDVLPIFQKLSRFFQIEDFDLSILKPIVSATATTLQAQKGSSGQNLQEFLSAMTEHPRGEREGESRLYYKGVELANCSPGHLQHFEHLKDSYLESVRGSLLDRFPSGVLEAVSSFSAIFNPKCYPQTLEDIGTYGVSELNFLLQAYSQVVVSERAMSDFPLFKRIVFSLSQLSFRDLCVKLVYSSSEMHELFPDFAVLAAIALALPLGSVLAKKISRGRELLKRGRSRCTKDEGLSNLMKIAIDGPAIDEFDFALAIEYYESMRESGFIKTQVK", "length": 717, "header": "tr|A0A8V0ZQZ2-1|A0A8V0ZQZ2_CHICK Isoform 1 of Zinc finger protein 385C OS=Gallus gallus OX=9031 GN=ZNF385C PE=4 SV=1 CANONICAL=A0A8V0ZQZ2-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2UG52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2/entry#A0A3Q2UG52-1", "sequence": { "sequence": "MVPPGKKPAGETSNSNKKCKRYFNEHWKEEFTWLEFDYERKLMFCIECRQALVKNKHGKAENAFTVGTDNFQRHALLRHVTSGAHRQALAVNREQMAFEARGHAELRSVLKVEVNPAKVAVLTTVYWMAKEEILDEKCSSLLDLQKFNLCQALLASEHSERYHAGSLRDMQAAMAKVLHNEDRHRIKASPFVGLVVDETVDAMEHRSLAVFSTTVSPCSGQTSATFLGSFELLAGEAATVTGKVGEVLRAFGIPAMKLTWLSAHSASLGAERRSGAGTALSSLCPLLTEMHCLSHGSSLLPTHSSLSIEYLQKYETTVDAIYRLYSSPTGESSGLQELWSVLDLCEIDLGSPRAICWTSIFPAVEAIDSSWPTLVLLLENEAERSPVALGLCQELKKFHFVAFTKILLDVLPIFQKLSRFFQIEDFDLSILKPIVSATATTLQAQKGSSGQNLQEFLSAMTEHPRGEREGESRLYYKGVELANCSPGHLQHFEHLKDSYLESVRGSLLDRFPSGVLEAVSSFSAIFNPKCYPQTLEDIGTYGVSELNFLLQAYSQVVVSERAMSDFPLFKRIVFSLSQLSFRDLCVKLVYSSSEMHELFPDFAVLAAIALALPLGSVLAKKISRGRELLKRGRSRCTKDEGLSNLMKIAIDGPAIDEFDFALAIEYYESMRESGFIKTQVK", "length": 681, "header": "tr|A0A3Q2UG52-1|A0A8V0ZQZ2_CHICK Computationally mapped isoform of Zinc finger protein 385C OS=Gallus gallus OX=9031 GN=ZNF385C PE=4 SV=1 CANONICAL=A0A8V0ZQZ2-1" }, "locus": { "chromosome": "27", "start_pos": 4779251, "end_pos": 4775241, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054979.1", "url": "https://www.ensembl.org/id/ENSGALT00010054979.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033243.1", "url": "https://www.ensembl.org/id/ENSGALP00010033243.1" } ] } }, { "isoform_ac": "A0A8V0ZQY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2/entry#A0A8V0ZQY7-1", "sequence": { "sequence": "MLLGPSGHSSPLLASLPIPGRPLHSPLDIKHFLTFRLNGTSPLNLFPNFNTMDPVQKAVISHTFGVPAPLKKKQFISCNICHLRFNSANQAEAHYKGHKHARRLKAIEAMKSKQKAVGAVGRDSTADFTPGLEGDEDPSSAAPPSDPKETDGDGPDVALPPGSEQPPAELPGSAAPLGSPPPSELSEAASDAASITSSAAHGAEAQTAESGSSSGSAPDGEKEGRKGKQHLYCPTCKVTVNSLSQLEAHNTGAKHKSMLEGHSAQLRRGRGKLLARAGHKAKRIGNKGSINIQNKAFHCQVCEIYVNSETQLKQHMSSRRHKDRLAGKPPKPKYSPYNKLQKNAALASKLALQKHLTKALATRFLPSPLTTAVCAMPGPLALRPAAATTLFQAPILGPALFRTPPAHVRTTPGPIVFAPY", "length": 420, "header": "tr|A0A8V0ZQY7-1|A0A8V0ZQY7_CHICK Computationally mapped isoform of Zinc finger protein 385C OS=Gallus gallus OX=9031 GN=ZNF385C PE=4 SV=1 CANONICAL=A0A8V0ZQZ2-1" }, "locus": { "chromosome": "27", "start_pos": 4787133, "end_pos": 4761682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054989.1", "url": "https://www.ensembl.org/id/ENSGALT00010054989.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033250.1", "url": "https://www.ensembl.org/id/ENSGALP00010033250.1" } ] } }, { "isoform_ac": "A0A8V0ZQZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2/entry#A0A8V0ZQZ2-1", "sequence": { "sequence": "MKRPLSPSHSPESGLRLVEVTSCPPGPPEQRTKREKKHQSFTLCEVCNIQLNSAAQAQIHYNGKSHQKRLKQLNKGKMPAAQECRQALVKNKHGKAENAFTVGTDNFQRHALLRHVTSGAHRQALAVNREQMAFEARGHAELRSVLKVEVNPAKVAVLTTVYWMAKEEILDEKCSSLLDLQKFNLCQALLASEHSERYHAGSLRDMQAAMAKVLHNEDRHRIKASPFVGLVVDETVDAMEHRSLAVFSTTVSPCSGQTSATFLGSFELLAGEAATVTGKVGEVLRAFGIPAMKLTWLSAHSASLGAERRSGAGTALSSLCPLLTEMHCLSHGSSLLPTHSSLSIEYLQKYETTVDAIYRLYSSPTGESSGLQELWSVLDLCEIDLGSPRAICWTSIFPAVEAIDSSWPTLVLLLENEAERSPVALGLCQELKKFHFVAFTKILLDVLPIFQKLSRFFQIEDFDLSILKPIVSATATTLQAQKGSSGQNLQEFLSAMTEHPRGEREGESRLYYKGVELANCSPGHLQHFEHLKDSYLESVRGSLLDRFPSGVLEAVSSFSAIFNPKCYPQTLEDIGTYGVSELNFLLQAYSQVVVSERAMSDFPLFKRIVFSLSQLSFRDLCVKLVYSSSEMHELFPDFAVLAAIALALPLGSVLAKKISRGRELLKRGRSRCTKDEGLSNLMKIAIDGPAIDEFDFALAIEYYESMRESGFIKTQVK", "length": 717, "header": "tr|A0A8V0ZQZ2-1|A0A8V0ZQZ2_CHICK Isoform 1 of Zinc finger protein 385C OS=Gallus gallus OX=9031 GN=ZNF385C PE=4 SV=1 CANONICAL=A0A8V0ZQZ2-1" }, "locus": { "chromosome": "27", "start_pos": 4796240, "end_pos": 4775241, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055001.1", "url": "https://www.ensembl.org/id/ENSGALT00010055001.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033255.1", "url": "https://www.ensembl.org/id/ENSGALP00010033255.1" } ] } }, { "isoform_ac": "A0A8V0ZWK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2/entry#A0A8V0ZWK5-1", "sequence": { "sequence": "MSLWLLSVLGLPLLLGRSQCGCRAAHSAAGAVPLPRAFKDHLYFSLPPSCPTHPSLPQAAMAKVLHNEDRHRIKASPFVGLVVDETVDAMEHRSLAVFSTTVSPCSGQTSATFLGSFELLAGEAATVTGKVGEVLRAFGIPAMKLTWLSAHSASLGAERRSGAGTALSSLCPLLTEMHCLSHGSSLLPTHSSLSIEYLQKYETTVDAIYRLYSSPTGESSGLQELWSVLDLCEIDLGSPRAICWTSIFPAVEAIDSSWPTLVLLLENEAERSPVALGLCQELKKFHFVAFTKILLDVLPIFQKLSRFFQIEDFDLSILKPIVSATATTLQAQKGSSGQNLQEFLSAMTEHPRGEREGESRLYYKGVELANCSPGHLQHFEHLKDSYLESVRGSLLDRFPSGVLEAVSSFSAIFNPKCYPQTLEDIGTYGVSELNFLLQAYSQVVVSERAMSDFPLFKRIVFSLSQLSFRDLCVKLVYSSSEMHELFPDFAVLAAIALALPLGSVLAKKISRGRELLKRGRSRCTKDEGLSNLMKIAIDGPAIDEFDFALAIEYYESMRESGFIKTQVK", "length": 568, "header": "tr|A0A8V0ZWK5-1|A0A8V0ZQZ2_CHICK Computationally mapped isoform of Zinc finger protein 385C OS=Gallus gallus OX=9031 GN=ZNF385C PE=4 SV=1 CANONICAL=A0A8V0ZQZ2-1" }, "locus": { "chromosome": "27", "start_pos": 4776944, "end_pos": 4775241, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054983.1", "url": "https://www.ensembl.org/id/ENSGALT00010054983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033247.1", "url": "https://www.ensembl.org/id/ENSGALP00010033247.1" } ] } }, { "isoform_ac": "A0A8V0ZWK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2/entry#A0A8V0ZWK8-1", "sequence": { "sequence": "MLQTAAEAGGWAGMKRPLSPSHSPESGLRLVEVTSCPPGPPEQRTKREKKHQSFTLCEVCNIQLNSAAQAQIHYNGKSHQKRLKQLNKGKMPAAQGPSGHSSPLLASLPIPGRPLHSPLDIKHFLTFRLNGTSPLNLFPNFNTMDPVQKAVISHTFGVPAPLKKKQFISCNICHLRFNSANQAEAHYKGHKHARRLKAIEAMKSKQKAVGAVGRDSTADFTPGLEGDEDPSSAAPPSDPKETDGDGPDVALPPGSEQPPAELPGSAAPLGSPPPSELSEAASDAASITSSAAHGAEAQTAESGSSSGSAPDGEKEGRKGKQHLYCPTCKVTVNSLSQLEAHNTGAKHKSMLEGHSAQLRRGRGKLLARAGHKAKRIGNKGSINIQNKAFHCQVCEIYVNSETQLKQHMSSRRHKDRLAGKPPKPKYSPYNKLQKNAALASKLALQKHLTKALATRFLPSPLTTAVCAMPGPLALRPAAATTLFQAPILGPALFRTPPAHVRTTPGPIVFAPY", "length": 512, "header": "tr|A0A8V0ZWK8-1|A0A8V0ZQZ2_CHICK Computationally mapped isoform of Zinc finger protein 385C OS=Gallus gallus OX=9031 GN=ZNF385C PE=4 SV=1 CANONICAL=A0A8V0ZQZ2-1" }, "locus": { "chromosome": "27", "start_pos": 4812407, "end_pos": 4761682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054994.1", "url": "https://www.ensembl.org/id/ENSGALT00010054994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033252.1", "url": "https://www.ensembl.org/id/ENSGALP00010033252.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420030", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420030", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GUU1-1", "protein_name": "Uncharacterized protein C17orf113", "gene_name": "C17orf113", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPPGKKPAGEASNSNKKCKRYFNEHWKEEFTWLDFDYERKLMFCLECRQALVRNKHGKAENAFTVGTDNFQRHALLRHVTSGAHRQALAVNQGQPPFEGQAEGGGACPGLATTPASRGVKVELDPAKVAVLTTVYCMAKEDVPNDRCSALLELQRFNLCQALLGTEHGDYYSPRRVRDMQVAIASVLHTEACQRLKASPYVGLVLDETRDWPESHSLALFATSVSPCDGQPATTFLGSVELQEGEATAGQLLDILQAFGVSAPKLAWLSSSLPSERLGSVGPQLRATCPLLAELHCLPGRTDPEPPAYLGQYESILDALFRLHGGPSSHLVPELRAALDLAAIDLAGPRPVPWASLLPVVEAVAEAWPGLVPTLEAAALASPVAGSLALALRQFTFVAFTHLLLDALPSVQKLSLVLQAEEPDLALLQPLVMAAAASLQAQRGSGGARLQGFLQELASMDPDASSGRCTYRGVELLGYSEAAVRGLEWLRGSFLDSMRKGLQDSYPGPSLDAVAAFAAIFDPRRYPQAPEELGTHGEGALRVLLRGFAPAVVRQRALGDFALFKRVVFGLGRLGPRALCTQLACAHSELHELFPDFAALAALALALPAGAGLLDKVGRSRELRWWGQSGAGEGRGGHMVKIAVDGPPLHEFDFGLAVEFLESGWGEGFLGSQLT", "length": 675 }, "evidence": [ { "id": "A0A8V0ZQZ2", "url": "https://omabrowser.org/oma/group/A0A8V0ZQZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ2" }, { "id": "SM00451", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00451" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U1-type", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 73, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 519, "end_pos": 521 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZN45-1", "uniprot_ac": "A0A8V0ZN45", "uniprot_id": "A0A8V0ZN45_CHICK", "mass": { "chemical_mass": 42279.0, "monoisotopic_mass": 42279.0 }, "refseq": { "ac": "XP_015141922", "name": "alpha-parvin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141922" }, "gene_names": [ { "name": "PARVA", "type": "recommended", "evidence": [ { "id": "A0A8V0ZN45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ] }, { "name": "PARVA", "type": "synonym", "evidence": [ { "id": "XP_015141922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141922" } ] } ], "protein_names": [ { "name": "Parvin alpha", "type": "synonym", "evidence": [ { "id": "A0A8V0ZN45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45/entry#names_and_taxonomy" } ] }, { "name": "alpha-parvin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141922" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141922" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PARVA", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45", "locus": { "chromosome": "5", "start_pos": 7589683, "end_pos": 7648820, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021919", "url": "https://www.ensembl.org/id/ENSGALG00010021919" } ] } } ], "crossref": [ { "id": "A0A8V0ZN45", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZN45", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005438", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005438", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21335", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21335", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423030", "url": "https://www.ncbi.nlm.nih.gov/gene/423030", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423030", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423030", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VDLLIYW", "url": "https://omabrowser.org/oma/group/VDLLIYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL25", "url": "https://www.orthodb.org/?gene=A0A8V0ZL25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN42", "url": "https://www.orthodb.org/?gene=A0A8V0ZN42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN45", "url": "https://www.orthodb.org/?gene=A0A8V0ZN45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P5V9", "url": "https://www.orthodb.org/?gene=F1P5V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12114:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12114:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-446343", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446343", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-446388", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446388", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015141922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141922", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P5V9", "url": "https://www.uniprot.org/uniprotkb/F1P5V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P5V9-1", "url": "https://www.uniprot.org/uniprotkb/F1P5V9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSPQKSPSSPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEAFSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372, "header": "tr|A0A8V0ZN45-1|A0A8V0ZN45_CHICK Isoform 1 of Parvin alpha OS=Gallus gallus OX=9031 GN=PARVA PE=1 SV=1 CANONICAL=A0A8V0ZN45-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZL25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45/entry#A0A8V0ZL25-1", "sequence": { "sequence": "MASSPQKSPSSPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEAFSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEGMIETDA", "length": 354, "header": "tr|A0A8V0ZL25-1|A0A8V0ZN45_CHICK Computationally mapped isoform of Parvin alpha OS=Gallus gallus OX=9031 GN=PARVA PE=1 SV=1 CANONICAL=A0A8V0ZN45-1" }, "locus": { "chromosome": "5", "start_pos": 7648744, "end_pos": 7596532, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053305.1", "url": "https://www.ensembl.org/id/ENSGALT00010053305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032126.1", "url": "https://www.ensembl.org/id/ENSGALP00010032126.1" } ] } }, { "isoform_ac": "A0A8V0ZN42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45/entry#A0A8V0ZN42-1", "sequence": { "sequence": "MASSPQKSPSSPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEAFSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEV", "length": 348, "header": "tr|A0A8V0ZN42-1|A0A8V0ZN42_CHICK Computationally mapped isoform of Parvin alpha OS=Gallus gallus OX=9031 GN=PARVA PE=1 SV=1 CANONICAL=A0A8V0ZN45-1" }, "locus": { "chromosome": "5", "start_pos": 7648744, "end_pos": 7595643, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053299.1", "url": "https://www.ensembl.org/id/ENSGALT00010053299.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032122.1", "url": "https://www.ensembl.org/id/ENSGALP00010032122.1" } ] } }, { "isoform_ac": "A0A8V0ZN45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45/entry#A0A8V0ZN45-1", "sequence": { "sequence": "MASSPQKSPSSPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEAFSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372, "header": "tr|A0A8V0ZN45-1|A0A8V0ZN45_CHICK Isoform 1 of Parvin alpha OS=Gallus gallus OX=9031 GN=PARVA PE=1 SV=1 CANONICAL=A0A8V0ZN45-1" }, "locus": { "chromosome": "5", "start_pos": 7648744, "end_pos": 7593464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053307.1", "url": "https://www.ensembl.org/id/ENSGALT00010053307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032127.1", "url": "https://www.ensembl.org/id/ENSGALP00010032127.1" } ] } }, { "isoform_ac": "F1P5V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45/entry#F1P5V9-1", "sequence": { "sequence": "MGCGAFCPKVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRNDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEAFSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 336, "header": "tr|F1P5V9-1|A0A8V0ZN45_CHICK Computationally mapped isoform of Parvin alpha OS=Gallus gallus OX=9031 GN=PARVA PE=1 SV=4 CANONICAL=A0A8V0ZN45-1" }, "locus": { "chromosome": "5", "start_pos": 7621194, "end_pos": 7593464, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053293.1", "url": "https://www.ensembl.org/id/ENSGALT00010053293.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032118.1", "url": "https://www.ensembl.org/id/ENSGALP00010032118.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423030", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423030", "resource": "KEGG Pathway" }, { "id": "R-GGA-446343", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446343", "resource": "Reactome", "description": "Localization of the PINCH-ILK-PARVIN complex to focal adhesions" }, { "id": "R-GGA-446388", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446388", "resource": "Reactome", "description": "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B7K9-1", "protein_name": "Parvin alpha", "gene_name": "PARVA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "A0A8V0ZN45", "url": "https://omabrowser.org/oma/group/A0A8V0ZN45/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1LMM6-1", "protein_name": "Parvin alpha", "gene_name": "PARVA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFGASSLLPAAAGAGPERSAPCRAEGGAREGEREGKGERELPRMLGIIPLPFGKPQPQSRRARRVRPAPAPRPDRPAAARSAAMATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDTVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEETLQMEVEDLQLDPHWNPPDDPG", "length": 453 }, "evidence": [ { "id": "A0A8V0ZN45", "url": "https://omabrowser.org/oma/group/A0A8V0ZN45/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8C2QGY3-1", "protein_name": "Alpha-parvin isoform X1", "gene_name": "Parva", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSEFQEEGMNAINLPLSPISFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "A0A8V0ZN45", "url": "https://omabrowser.org/oma/group/A0A8V0ZN45/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9NVD7-1", "protein_name": "Alpha-parvin", "gene_name": "PARVA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSPQKSPSVPKSPTPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTMLEENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEKLESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPRSIKWNVDSVHAKSLVAILHLLVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE", "length": 372 }, "evidence": [ { "id": "A0A8V0ZN45", "url": "https://omabrowser.org/oma/group/A0A8V0ZN45/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VWD0-1", "protein_name": "Parvin, isoform A", "gene_name": "parvin", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTLNRPKSPHTPTAIKKGEKEDSFWDKFSTLGRKRGTREVKKVQEEGKYAIDSPGSPSQYDIPPEDYALREHEQRAVIDPQSISDPQVIKLQRILVDWINDELAEQRIIVQHLEEDMYDGQVLHKLWEKLTGKKLDVPEVTQSEQGQHEKLNIVLKAVNHTLGFHQKIPKWSVASVHSKNIVAILHLLVALVRHFRAPVRLPENVFVTVVIAEKNAGVLNAQKFQEQITSEYDDLGMRCEKDAFDTLIDCAPDKLAVVKKSLITFVNKHLAKLNFEISDLNTDFRDGVYLCLLMGLLGGFFVPLHEFHLTPQDVDQMVSNVAFAFDLMQDVGLPKPKARPEDIVNMDLKSTLRVLYSLFTMFRDFA", "length": 367 }, "evidence": [ { "id": "A0A8V0ZN45", "url": "https://omabrowser.org/oma/group/A0A8V0ZN45/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "protein kinase inhibitor activity", "id": "GO:0004860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004860", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" }, { "name": "establishment or maintenance of cell polarity regulating cell shape", "id": "GO:0071963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071963", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN45", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZN45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN45" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 202, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 326, "end_pos": 328 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNH4-1", "uniprot_ac": "A0A8V0ZNH4", "uniprot_id": "A0A8V0ZNH4_CHICK", "mass": { "chemical_mass": 78795.0, "monoisotopic_mass": 78795.0 }, "refseq": {}, "gene_names": [ { "name": "ZFAND4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH4" } ] } ], "protein_names": [ { "name": "Zinc finger AN1-type containing 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZFAND4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH4", "locus": { "chromosome": "6", "start_pos": 18525112, "end_pos": 18546743, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021096", "url": "https://www.ensembl.org/id/ENSGALG00010021096" } ] } } ], "crossref": [ { "id": "A0A8V0ZNH4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01802", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01802", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423771", "url": "https://www.ncbi.nlm.nih.gov/gene/423771", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAE3", "url": "https://www.orthodb.org/?gene=A0A8V0ZAE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHF2", "url": "https://www.orthodb.org/?gene=A0A8V0ZHF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNH4", "url": "https://www.orthodb.org/?gene=A0A8V0ZNH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46728", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46728", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46728:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46728:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZAE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNH4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANKKEPPFFNEDNMGPFHYKLPFYETMELFIETLTGTCFELRVSPFETVISVKAKIQRLEGIPISQQHLIWNNVELKDDYCLNDYNISEGCTLKLVLAMRGGPINTRRVPVEDPIREIAEYMDPSRDEIWEKGPSNKQVTFLVYREGDQLNFFRVVDRGDGTLTPLSESGGSVYNLYADDEDETEASPSGQQIIENSITMNKMKLLKAKMENMNLSKKPKKTVKVKPRPPTAPRPSNGSVAARHRFLRVLPHIGQSCLPPSGNSYPSESSQNALTALASLATTGRTMPSPANDFLKEDDTWQSNSWSQSVSSIRLPPKISRVELENAKVPTNTILTPVSSLPANLEEVSENATSATEEDSVLYPNLTNVELYGTEEKLLSETDTFALFTEANTTEQCSEIYDTGKVNPELELSDGNEESKVIEQHKKPISKVLSTAAMGTGLLSTRQLSPQKSMLLSPLWYSSQVAHHGSLKPQTQPKCFESCNLRSTASPDTLRSLEFHSIADSSFSRTARFHSMKLDSLSKRPDRIAKAETRDITDVANKASKEPASSVNNLGFLASLARSASRESLQSSCGTGRFRTSGIALPANLQSFHEESFRKTAPPNEAAEYILSAHGLGMNGSNAAVGKRVGEATHLPPVNGSIQAKKKIAKYCFLCGKKTGLATSYECRCGNNFCATHRYAETHTCTYDYKSAGRRYLQETNPVVSAPKLPKI", "length": 713, "header": "tr|A0A8V0ZNH4-1|A0A8V0ZNH4_CHICK Isoform 1 of Zinc finger AN1-type containing 4 OS=Gallus gallus OX=9031 GN=ZFAND4 PE=4 SV=1 CANONICAL=A0A8V0ZNH4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH4/entry#A0A8V0ZAE3-1", "sequence": { "sequence": "MANKKEPPFFNEDNMGPFHYKLPFYETMELFIETLTGTCFELRVSPFETVISVKAKIQRLEGIPISQQHLIWNNVELKDDYCLNDYNISEGCTLKLVLAMRGGPINTRRVPVEDPIREIAEYMDPSRDEIWEKGPSNKQVTFLVYREGDQLNFFRVVDRGDGTLTPLSESLSGGSVYNLYADDEDETEASPSGQQIIENSITMNKMKLLKAKMENMNLSKKPKKTVKVKPRPPTAPRPSNGSVAARHRFLRVLPHIGQSCLPPSGNSYPSESSQNALTALASLATTGRTMPSPANDFLKEDDTWQSNSWSQSVSSIRLPPKISRVELENAKVPTNTILTPVSSLPANLEEVSENATSATEEDSVLYPNLTNVELYGTEEKLLSETDTFALFTEANTTEQCSEIYDTGKVNPELELSDGNEESKVIEQHKKPISKVLSTAAMGTGLLSTRQLSPQKSMLLSPLWYSSQVAHHGSLKPQTQPKCFESCNLRSTASPDTLRSLEFHSIADSSFSRTARFHSMKLDSLSKRPDRIAKAETRDITDVANKASKEPASSVNNLGFLASLARSASRESLQSSCGTGRFRTSGIALPANLQSFHEESFRKTAPPNEAAEYILSAHGLGMNGSNAAVGKRVGEATHLPPVNGSIQAKKKIAKYCFLCGKKTGLATSYECRSAKLQEIKFRNIVHALLWRIMFC", "length": 694, "header": "tr|A0A8V0ZAE3-1|A0A8V0ZNH4_CHICK Computationally mapped isoform of Zinc finger AN1-type containing 4 OS=Gallus gallus OX=9031 GN=ZFAND4 PE=4 SV=1 CANONICAL=A0A8V0ZNH4-1" }, "locus": { "chromosome": "6", "start_pos": 18546041, "end_pos": 18527992, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051059.1", "url": "https://www.ensembl.org/id/ENSGALT00010051059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030250.1", "url": "https://www.ensembl.org/id/ENSGALP00010030250.1" } ] } }, { "isoform_ac": "A0A8V0ZHF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH4/entry#A0A8V0ZHF2-1", "sequence": { "sequence": "MANKKEPPFFNEDNMGPFHYKLPFYETMELFIETLTGTCFELRVSPFETVISVKAKIQRLEGIPISQQHLIWNNVELKDDYCLNDYNISEGCTLKLVLAMRGGPINTRRVPVEDPIREIAEYMDPSRDEIWEKGPSNKQVTFLVYREGDQLNFFRVVDRGDGTLTPLSESLSGGSVYNLYADDEDETEASPSGQQIIENSITMNKMKLLKAKMENMNLSKKPKKTVKVKPRPPTAPRPSNGSVAARHRFLRVLPHIGQSCLPPSGNSYPSESSQNALTALASLATTGRTMPSPANDFLKEDDTWQSNSWSQSVSSIRLPPKISRVELENAKVPTNTILTPVSSLPANLEEVSENATSATEEDSVLYPNLTNVELYGTEEKLLSETDTFALFTEANTTEQCSEIYDTGKVNPELELSDGNEESKVIEQHKKPISKVLSTAAMGTGLLSTRQLSPQKSMLLSPLWYSSQVAHHGSLKPQTQPKCFESCNLRSTASPDTLRSLEFHSIADSSFSRTARFHSMKLDSLSKRPDRIAKAETRDITDVANKASKEPASSVNNLGFLASLARSASRESLQSSCGTGRFRTSGIALPANLQSFHEESFRKTAPPNEAAEYILSAHGLGMNGSNAAVGKRVGLQPKPKRFGKRKARRTWMLKIADSTLISSSFCDKH", "length": 668, "header": "tr|A0A8V0ZHF2-1|A0A8V0ZNH4_CHICK Computationally mapped isoform of Zinc finger AN1-type containing 4 OS=Gallus gallus OX=9031 GN=ZFAND4 PE=4 SV=1 CANONICAL=A0A8V0ZNH4-1" }, "locus": { "chromosome": "6", "start_pos": 18546041, "end_pos": 18530611, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051058.1", "url": "https://www.ensembl.org/id/ENSGALT00010051058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030249.1", "url": "https://www.ensembl.org/id/ENSGALP00010030249.1" } ] } }, { "isoform_ac": "A0A8V0ZNH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH4/entry#A0A8V0ZNH4-1", "sequence": { "sequence": 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"name": "myotubularin-related protein 13 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015141866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141866" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141866" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SBF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8", "locus": { "chromosome": "5", "start_pos": 8894866, "end_pos": 8662376, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021114", "url": "https://www.ensembl.org/id/ENSGALG00010021114" } ] } } ], "crossref": [ { "id": "ENSGALG00000005716", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005716", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZAN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C7M2", "url": "https://www.uniprot.org/uniprotkb/E1C7M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C7M2-1", "url": "https://www.uniprot.org/uniprotkb/E1C7M2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLADYFIVVGYDHEKTAGPAEGLGKIIQRFPQKDWEDTPFPQGIELFCQPGGWQLSKERKQPTFFVVVLTDIDSERHYCSCLTFYEAEINLQGTKETEGEEESGLIAPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLNVSLEALIANLCSCLVPASGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFRNDIHELLDVIIADLDGGTIKIPECIHLSQLPEPLLHQTQMALSLVLHPDLETADYAFPPPRTALSHTKMLDKEVRAIFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKAAFLGQRGLIENDFLTKVLNGMAFAGFVSERGPPFRACDLFDELVAFEVERIKADEGNPPKMIKHVRELAEQLFKNENPNPHIAFQKVPRPTEGSHLRVHILPFPRINECRVQELLQEGLARSQGAPSATRGDKKCVVPAGPPVVSIMEKGSTVFNSAQRLEVVRNCISFIFENKFLETEKTLPAALRALKGKAARHCLTQELGLHVKQNRAILDHQQFDYIVRMMNCALQDCSSSEEYSVAAALLPLTTAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYSNVQNQVRSLYLTAKEDNHAVHPRQKEKNSVGPDHDKTAMDLAAEQLRLWPTLNKQTQQELVQNEESTVFSQAIHFANLMVYLLVPLDTSKNKLLRASATGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENNDVANAVVRFITRFIDKVCTESGVTQDHIKGLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPTLLPGEEFVCEGLRVLLDPDGREEATGGLLGGPHILPAEGALFLTTYRIIFKGTPHDQLVGEQTVIRSFPIASVTKEKKITIQNQLQQSMQEGLQITSATFQLIKVAFDEEVSPEVVEIFKKQLMKFRYPQSIFSAFAFAAGQTAPQIILPKQKEKNTSFRTFSKSIVKGAKRAGKMTIGRQYLLKKKTGTIMEERGNRPGWNEDDDVSVSDDSDLHTSGTLKASEKSTMEQLVERACFRDYQRLGLGTISSNTSRSKMEYLRITALNRMYSLCRSYPGLLVVPQSVQDSSLQRVARCYRHNRLPVVCWRNTKNSSLLLRSGGFHGKGVVGLFKSQNTHTAAPASLESSSSIEQEKYLQALLNVISVHCKMNGSNTLTVRPTIALSPGTDRRASRMSTVFKQVVPGHLDVNLSNSFARGVVGYRDKCFTHSNSKSATKGRVHQGVWASLRSSNRFINAQTPFIDVGARLAGKDNTTSYSSTFLQSQLLRRQAALYIFGEKSQLRGFKLDFALNCEFVPVEFSDIRQTKASFKKLLRACVPSTIPTDSEATFLKALGESEWFPQLHRIMQLGVIISELLENGSSVMVCLEDGWDITAQVVSLVQLLSDPFYRTLEGFRMLVEKEWLSFGHKFSQRSNLTLNCQGSGFAPIFLQFLDCVHQIHNQYPTEFEFNQYYLKFLAFHHISNRFKTFLLDSDYERLEHGTLFEDKGDKHNKKGVCIWECIEKMHKRSPIFFNYLYAPTEIEALKPNVSMSSLKKWDYYVEEILATGPSYDWNMVAAKCSALEEADQTDGSVSQKKRKIVWPCYDDVKKIQPDAISSLLNEIERLESKLNQNPERWQLLWERVKMNLKDDTRQDNLQRHPSGSSGMMSANLHSYQKRSLLEMPDNGLGEEQSASISPSNGVDRRATTLYNHFTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVETVIPASPTIGAPKHASEKAFFDLKTNKRVYNFCAQDAQSAQQWMDRIQSCISDA", "length": 1901, "header": "tr|A0A8V0ZNP8-1|A0A8V0ZNP8_CHICK Isoform 1 of SET binding factor 2 OS=Gallus gallus OX=9031 GN=SBF2 PE=3 SV=1 CANONICAL=A0A8V0ZNP8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZAN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8/entry#A0A8V0ZAN6-1", "sequence": { "sequence": "MARLADYFIVVGYDHEKTAGPAEGLGKIIQRFPQKDWEDTPFPQGIELFCQPGGWQLSKERKQPTFFVVVLTDIDSERHYCSCLTFYEAEINLQGTKETEGEEESGLIAPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLNVSLEALIANLCSCLVPASGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFRNDIHELLDVIIADLDGGTIKIPECIHLSQLPEPLLHQTQMALSLVLHPDLETADYAFPPPRTALSHTKMLDKEVRAIFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKAAFLGQRGLIENDFLTKVLNGMAFAGFVSERGPPFRACDLFDELVAFEVERIKADEGNPPKMIKHVRELAEQLFKNENPNPHIAFQKVPRPTEGSHLRVHILPFPRINECRVQELLQEGLARSQGAPSATRGDKKCVVPAGPPVVSIMEKGSTVFNSAQRLEVVRNCISFIFENKFLETEKTLPAALRALKGKAARHCLTQELGLHVKQNRAILDHQQFDYIVRMMNCALQDCSSSEEYSVAAALLPLTTAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYSNVQNQVRSLYLTAKEDNHAVHPRQKEKNSVGPDHDKTAMDLAAEQLRLWPTLNKQTQQELVQNEESTVFSQAIHFANLMVYLLVPLDTSKNKLLRASATGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENNDVANAVVRFITRFIDKVCTESGVTQDHIKGLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPTLLPGEEFVCEGLRVLLDPDGREEATGGLLGGPHILPAEGALFLTTYRIIFKGTPHDQLVGEQTVIRSFPIASVTKEKKITIQNQLQQSMQEGLQITSATFQLIKVAFDEEVSPEVVEIFKKQLMKFRYPQSIFSAFAFAAGQTAPQIILPKQKEKNTSFRTFSKSIVKGAKRAGKMTIGRQYLLKKKTGTIMEERGNRPGWNEDDDVSVSDDSDLHTSGTLKASEKSTMEQLVERACFRDYQRLGLGTISSNTSRSKMEYLRITALNRMYSLCRSYPGLLVVPQSVQDSSLQRVARCYRHNRLPVVCWRNTKNSSLLLRSGGFHGKGVVGLFKSQNTHTAAPASLESSSSIEQEKYLQALLNVISVHCKMNGSNTLTVRPTIALSPVVGYRDKCFTHSNSKSATKGRVHQGVWASLRSSNRFINAQTPFIDVGARLAGKDNTTSYSSTFLQSQLLRRQAALYIFGEKSQLRGFKLDFALNCEFVPVEFSDIRQTKASFKKLLRACVPSTIPTDSEATFLKALGESEWFPQLHRIMQLGVIISELLENGSSVMVCLEDGWDITAQVVSLVQLLSDPFYRTLEGFRMLVEKEWLSFGHKFSQRSNLTLNCQGSGFAPIFLQFLDCVHQIHNQYPTEFEFNQYYLKFLAFHHISNRFKTFLLDSDYERLEHGTLFEDKGDKHNKKGVCIWECIEKMHKRSPIFFNYLYAPTEIEALKPNVSMSSLKKWDYYVEEILATGPSYDWNMVAAKCSALEEADQTDGSVSQKKRKIVWPCYDDVKKIQPDAISSLLNEIERLESKLNQNPERWQLLWERVKMNLKDDTRQDNLQRHPSGSSGMMSANLHSYQKRSLLEMPDNGLGEEQSASISPSNGVDRRATTLYNHFTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVETVIPASPTIGAPKHASEKAFFDLKTNKRVYNFCAQDAQSAQQWMDRIQSCISDA", "length": 1869, "header": "tr|A0A8V0ZAN6-1|A0A8V0ZNP8_CHICK Computationally mapped isoform of SET binding factor 2 OS=Gallus gallus OX=9031 GN=SBF2 PE=3 SV=1 CANONICAL=A0A8V0ZNP8-1" }, "locus": { "chromosome": "5", "start_pos": 8892401, "end_pos": 8662518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051145.1", "url": "https://www.ensembl.org/id/ENSGALT00010051145.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030336.1", "url": "https://www.ensembl.org/id/ENSGALP00010030336.1" } ] } }, { "isoform_ac": "A0A8V0ZGA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8/entry#A0A8V0ZGA6-1", "sequence": { "sequence": "MDSLCVAAVQVIECDAYKSGPAEGLGKIIQRFPQKDWEDTPFPQGIELFCQPGGWQLSKERKQPTFFVVVLTDIDSERHYCSCLTFYEAEINLQGTKETEGEEESGLIAPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLNVSLEALIANLCSCLVPASGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFRNDIHELLDVIIADLDGGTIKIPECIHLSQLPEPLLHQTQMALSLVLHPDLETADYAFPPPRTALSHTKMLDKEVRAIFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKAAFLGQRGLIENDFLTKVLNGMAFAGFVSERGPPFRACDLFDELVAFEVERIKADEGNPPKMIKHVRELAEQLFKNENPNPHIAFQKVPRPTEGSHLRVHILPFPRINECRVQELLQEGLARSQGAPSATRGDKKCVVPAGPPVVSIMEKGSTVFNSAQRLEVVRNCISFIFENKFLETEKTLPAALRALKGKAARHCLTQELGLHVKQNRAILDHQQFDYIVRMMNCALQDCSSSEEYSVAAALLPLTTAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYSNVQNQVRSLYLTAKEDNHAVHPRQKEKNSVGPDHDKTAMDLAAEQLRLWPTLNKQTQQELVQNEESTVFSQAIHFANLMVYLLVPLDTSKNKLLRASATGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENNDVANAVVRFITRFIDKVCTESGVTQDHIKGLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPTLLPGEEFVCEGLRVLLDPDGREEATGGLLGGPHILPAEGALFLTTYRIIFKGTPHDQLVGEQTVIRSFPIASVTKEKKITIQNQLQQSMQEGLQITSATFQLIKVAFDEEVSPEVVEIFKKQLMKFRYPQSIFSAFAFAAGQTAPQIILPKQKEKNTSFRTFSKSIVKGAKRAGKMTIGRQYLLKKKTGTIMEERGNRPGWNEDDDVSVSDDSDLHTSGTLKASEKSTMEQLVERACFRDYQRLGLGTISSNTSRSKMEYLRITALNRMYSLCRSYPGLLVVPQSVQDSSLQRVARCYRHNRLPVVCWRNTKNSSLLLRSGGFHGKGVVGLFKSQNTHTAAPASLESSSSIEQEKYLQALLNVISVHCKMNGSNTLTVRPTIALSPGVWASLRSSNRFINAQTPFIDVGARLAGKDNTTSYSSTFLQSQLLRRQAALYIFGEKSQLRGFKLDFALNCEFVPVEFSDIRQTKASFKKLLRACVPSTIPTDSEATFLKALGESEWFPQLHRIMQLGVIISELLENGSSVMVCLEDGWDITAQVVSLVQLLSDPFYRTLEGFRMLVEKEWLSFGHKFSQRSNLTLNCQGSGFAPIFLQFLDCVHQIHNQYPTEFEFNQYYLKFLAFHHISNRFKTFLLDSDYERLEHGTLFEDKGDKHNKKGVCIWECIEKMHKRSPIFFNYLYAPTEIEALKPNVSMSSLKKWDYYVEEILATGPSYDWNMVAAKCSALEEADQTDGSVSQKKRKIVWPCYDDVKKIQPDAISSLLNEIERLESKLNQNPERWQLLWERVKMNLKDDTRQDNLQRHPSGSSGMMSANLHSYQKRSLLEMPDNGLGEEQSASISPSNGVDRRATTLYNHFTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVETVIPASPTIGAPKHASEKAFFDLKTNKRVYNFCAQDAQSAQQWMDRIQSCISDA", "length": 1845, "header": "tr|A0A8V0ZGA6-1|A0A8V0ZNP8_CHICK Computationally mapped isoform of SET binding factor 2 OS=Gallus gallus OX=9031 GN=SBF2 PE=3 SV=1 CANONICAL=A0A8V0ZNP8-1" }, "locus": { "chromosome": "5", "start_pos": 8892401, "end_pos": 8698919, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051121.1", "url": "https://www.ensembl.org/id/ENSGALT00010051121.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030312.1", "url": "https://www.ensembl.org/id/ENSGALP00010030312.1" } ] } }, { "isoform_ac": "A0A8V0ZHL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8/entry#A0A8V0ZHL2-1", "sequence": { "sequence": "MARLADYFIVVGYDHEKTGPAEGLGKIIQRFPQKDWEDTPFPQGIELFCQPGGWQLSKERKQPTFFVVVLTDIDSERHYCSCLTFYEAEINLQGTKETEGEEESGLIAPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLNVSLEALIANLCSCLVPASGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFRNDIHELLDVIIADLDGGTIKIPECIHLSQLPEPLLHQTQMALSLVLHPDLETADYAFPPPRTALSHTKMLDKEVRAIFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKAAFLGQRGLIENDFLTKVLNGMAFAGFVSERGPPFRACDLFDELVAFEVERIKADEGNPPKMIKHVRELAEQLFKNHGCNVLLLRKIPSCWNLFREGEPSW", "length": 487, "header": "tr|A0A8V0ZHL2-1|A0A8V0ZNP8_CHICK Computationally mapped isoform of SET binding factor 2 OS=Gallus gallus OX=9031 GN=SBF2 PE=3 SV=1 CANONICAL=A0A8V0ZNP8-1" }, "locus": { "chromosome": "5", "start_pos": 8801695, "end_pos": 8662518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051113.1", "url": "https://www.ensembl.org/id/ENSGALT00010051113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030304.1", "url": "https://www.ensembl.org/id/ENSGALP00010030304.1" } ] } }, { "isoform_ac": "A0A8V0ZHP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8/entry#A0A8V0ZHP5-1", "sequence": { "sequence": "MRWAEKNPLLKVETGVMKKQKEEQKDAAGPAEGLGKIIQRFPQKDWEDTPFPQGIELFCQPGGWQLSKERKQPTFFVVVLTDIDSERHYCSCLTFYEAEINLQGTKETEGEEESGLIAPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLNVSLEALIANLCSCLVPASGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFRNDIHELLDVIIADLDGGTIKIPECIHLSQLPEPLLHQTQMALSLVLHPDLETADYAFPPPRTALSHTKMLDKEVRAIFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKAAFLGQRGLIENDFLTKVLNGMAFAGFVSERGPPFRACDLFDELVAFEVERIKADEGNPPKMIKHVRELAEQLFKNENPNPHIAFQKVPRPTEGSHLRVHILPFPRINECRVQELLQEGLARSQGAPSATRGDKKCVVPAGPPVVSIMEKGSTVFNSAQRLEVVRNCISFIFENKFLETEKTLPAALRALKGKAARHCLTQELGLHVKQNRAILDHQQFDYIVRMMNCALQDCSSSEEYSVAAALLPLTTAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYSNVQNQVRSLYLTAKEDNHAVHPRQKEKNSVGPDHDKTAMDLAAEQLRLWPTLNKQTQQELVQNEESTVFSQAIHFANLMVYLLVPLDTSKNKLLRASATGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENNDVANAVVRFITRFIDKVCTESGVTQDHIKGLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPTLLPGEEFVCEGLRVLLDPDGREEATGGLLGGPHILPAEGALFLTTYRIIFKGTPHDQLVGEQTVIRSFPIASVTKEKKITIQNQLQQSMQEGLQITSATFQLIKVAFDEEVSPEVVEIFKKQLMKFRYPQSIFSAFAFAAGQTAPQIILPKQKEKNTSFRTFSKSIVKGAKRAGKMTIGRQYLLKKKTGTIMEERGNRPGWNEDDDVSVSDDSDLHTSGTLKASEKSTMEQLVERACFRDYQRLGLGTISSNTSRSKMEYLRITALNRMYSLCRSYPGLLVVPQSVQDSSLQRVARCYRHNRLPVVCWRNTKNSSLLLRSGGFHGKGVVGLFKSQNTHTAAPASLESSSSIEQEKYLQALLNVISVHCKMNGSNTLTVRPTIALSPGVWASLRSSNRFINAQTPFIDVGARLAGKDNTTSYSSTFLQSQLLRRQAALYIFGEKSQLRGFKLDFALNCEFVPVEFSDIRQTKASFKKLLRACVPSTIPTDSEATFLKALGESEWFPQLHRIMQLGVIISELLENGSSVMVCLEDGWDITAQVVSLVQLLSDPFYRTLEGFRMLVEKEWLSFGHKFSQRSNLTLNCQGSGFAPIFLQFLDCVHQIHNQYPTEFEFNQYYLKFLAFHHISNRFKTFLLDSDYERLEHGTLFEDKGDKHNKKGVCIWECIEKMHKRSPIFFNYLYAPTEIEALKPNVSMSSLKKWDYYVEEILATGPSYDWNMVAAKCSALEEADQTDGSVSQKKRKIVWPCYDDVKKIQPDAISSLLNEIERLESKLNQNPERWQLLWERVKMNLKDDTRQDNLQRHPSGSSGMMSANLHSYQKRSLLEMPDNGLGEEQSASISPSNGVDRRATTLYNHFTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVETVIPASPTIGAPKHASEKAFFDLKTNKRVYNFCAQDAQSAQQWMDRIQSCISDA", "length": 1854, "header": "tr|A0A8V0ZHP5-1|A0A8V0ZNP8_CHICK Computationally mapped isoform of SET binding factor 2 OS=Gallus gallus OX=9031 GN=SBF2 PE=3 SV=1 CANONICAL=A0A8V0ZNP8-1" }, "locus": { "chromosome": "5", "start_pos": 8892401, "end_pos": 8676956, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051127.1", "url": "https://www.ensembl.org/id/ENSGALT00010051127.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030318.1", "url": "https://www.ensembl.org/id/ENSGALP00010030318.1" } ] } }, { "isoform_ac": "A0A8V0ZNP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8/entry#A0A8V0ZNP3-1", "sequence": { "sequence": "MAEARGAPLAAMARLADYFIVVGYDHEKTAGPAEGLGKIIQRFPQKDWEDTPFPQGIELFCQPGGWQLSKERKQPTFFVVVLTDIDSERHYCSCLTFYEAEINLQGTKETEGEEESGLIAPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLNVSLEALIANLCSCLVPASGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFRNDIHELLDVIIADLDGGTIKIPECIHLSQLPEPLLHQTQMALSLVLHPDLETADYAFPPPRTALSHTKMLDKEVRAIFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKAAFLGQRGLIENDFLTKVLNGMAFAGFVSERGPPFRACDLFDELVAFEVERIKADEGNPPKMIKHVRELAEQLFKNENPNPHIAFQKVPRPTEGSHLRVHILPFPRINECRVQELLQEGLARSQGAPSATRGDKKCVVPAGPPVVSIMEKGSTVFNSAQRLEVVRNCISFIFENKFLETEKTLPAALRALKGKAARHCLTQELGLHVKQNRAILDHQQFDYIVRMMNCALQDCSSSEEYSVAAALLPLTTAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYSNVQNQVRSLYLTAKEDNHAVHPRQKEKNSVGPDHDKTAMDLAAEQLRLWPTLNKQTQQELVQNEESTVFSQAIHFANLMVYLLVPLDTSKNKLLRASATGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENNDVANAVVRFITRFIDKVCTESGVTQDHIKGLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPTLLPGEEFVCEGLRVLLDPDGREEATGGLLGGPHILPAEGALFLTTYRIIFKGTPHDQLVGEQTVIRSFPIASVTKEKKITIQNQLQQSMQEGLQITSATFQLIKVAFDEEVSPEVVEIFKKQLMKFRYPQSIFSAFAFAAGQTAPQIILPKQKEKNTSFRTFSKSIVKGAKRAGKMTIGRQYLLKKKTGTIMEERGNRPGWNEDDDVSVSDDSDLHTSGTLKASEKSTMEQLVERACFRDYQRLGLGTISSNTSRSKMEYLRITALNRMYSLCRSYPGLLVVPQSVQDSSLQRVARCYRHNRLPVVCWRNTKNSSLLLRSGGFHGKGVVGLFKSQNTHTAAPASLESSSSIEQEKYLQALLNVISVHCKMNGSNTLTVRPTIALSPGVWASLRSSNRFINAQTPFIDVGARLAGKDNTTSYSSTFLQSQLLRRQAALYIFGEKSQLRGFKLDFALNCEFVPVEFSDIRQTKASFKKLLRACVPSTIPTDSEATFLKALGESEWFPQLHRIMQLGVIISELLENGSSVMVCLEDGWDITAQVVSLVQLLSDPFYRTLEGFRMLVEKEWLSFGHKFSQRSNLTLNCQGSGFAPIFLQFLDCVHQIHNQYPTEFEFNQYYLKFLAFHHISNRFKTFLLDSDYERLEHGTLFEDKGDKHNKKGVCIWECIEKMHKRSPIFFNYLYAPTEIEALKPNVSMSSLKKWDYYVEEILATGPSYDWNMVAAKCSALEEADQTDGSVSQKKRKIVWPCYDDVKKIQPDAISSLLNEIERLESKLNQNPERWQLLWERVKMNLKDDTRQDNLQRHPSGSSGMMSANLHSYQKRSLLEMPDNGLGEEQSASISPSNGVDRRATTLYNHFTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVETVIPASPTIGAPKHASEKAFFDLKTNKRVYNFCAQDAQSAQQWMDRIQSCISDA", "length": 1856, "header": "tr|A0A8V0ZNP3-1|A0A8V0ZNP3_CHICK Computationally mapped isoform of SET binding factor 2 OS=Gallus gallus OX=9031 GN=SBF2 PE=3 SV=1 CANONICAL=A0A8V0ZNP8-1" }, "locus": { "chromosome": "5", "start_pos": 8892401, "end_pos": 8662403, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051136.1", "url": "https://www.ensembl.org/id/ENSGALT00010051136.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030326.1", "url": "https://www.ensembl.org/id/ENSGALP00010030326.1" } ] } }, { "isoform_ac": "A0A8V0ZNP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8/entry#A0A8V0ZNP8-1", "sequence": { "sequence": "MARLADYFIVVGYDHEKTAGPAEGLGKIIQRFPQKDWEDTPFPQGIELFCQPGGWQLSKERKQPTFFVVVLTDIDSERHYCSCLTFYEAEINLQGTKETEGEEESGLIAPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLNVSLEALIANLCSCLVPASGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFRNDIHELLDVIIADLDGGTIKIPECIHLSQLPEPLLHQTQMALSLVLHPDLETADYAFPPPRTALSHTKMLDKEVRAIFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKAAFLGQRGLIENDFLTKVLNGMAFAGFVSERGPPFRACDLFDELVAFEVERIKADEGNPPKMIKHVRELAEQLFKNENPNPHIAFQKVPRPTEGSHLRVHILPFPRINECRVQELLQEGLARSQGAPSATRGDKKCVVPAGPPVVSIMEKGSTVFNSAQRLEVVRNCISFIFENKFLETEKTLPAALRALKGKAARHCLTQELGLHVKQNRAILDHQQFDYIVRMMNCALQDCSSSEEYSVAAALLPLTTAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYSNVQNQVRSLYLTAKEDNHAVHPRQKEKNSVGPDHDKTAMDLAAEQLRLWPTLNKQTQQELVQNEESTVFSQAIHFANLMVYLLVPLDTSKNKLLRASATGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENNDVANAVVRFITRFIDKVCTESGVTQDHIKGLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPTLLPGEEFVCEGLRVLLDPDGREEATGGLLGGPHILPAEGALFLTTYRIIFKGTPHDQLVGEQTVIRSFPIASVTKEKKITIQNQLQQSMQEGLQITSATFQLIKVAFDEEVSPEVVEIFKKQLMKFRYPQSIFSAFAFAAGQTAPQIILPKQKEKNTSFRTFSKSIVKGAKRAGKMTIGRQYLLKKKTGTIMEERGNRPGWNEDDDVSVSDDSDLHTSGTLKASEKSTMEQLVERACFRDYQRLGLGTISSNTSRSKMEYLRITALNRMYSLCRSYPGLLVVPQSVQDSSLQRVARCYRHNRLPVVCWRNTKNSSLLLRSGGFHGKGVVGLFKSQNTHTAAPASLESSSSIEQEKYLQALLNVISVHCKMNGSNTLTVRPTIALSPGTDRRASRMSTVFKQVVPGHLDVNLSNSFARGVVGYRDKCFTHSNSKSATKGRVHQGVWASLRSSNRFINAQTPFIDVGARLAGKDNTTSYSSTFLQSQLLRRQAALYIFGEKSQLRGFKLDFALNCEFVPVEFSDIRQTKASFKKLLRACVPSTIPTDSEATFLKALGESEWFPQLHRIMQLGVIISELLENGSSVMVCLEDGWDITAQVVSLVQLLSDPFYRTLEGFRMLVEKEWLSFGHKFSQRSNLTLNCQGSGFAPIFLQFLDCVHQIHNQYPTEFEFNQYYLKFLAFHHISNRFKTFLLDSDYERLEHGTLFEDKGDKHNKKGVCIWECIEKMHKRSPIFFNYLYAPTEIEALKPNVSMSSLKKWDYYVEEILATGPSYDWNMVAAKCSALEEADQTDGSVSQKKRKIVWPCYDDVKKIQPDAISSLLNEIERLESKLNQNPERWQLLWERVKMNLKDDTRQDNLQRHPSGSSGMMSANLHSYQKRSLLEMPDNGLGEEQSASISPSNGVDRRATTLYNHFTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVETVIPASPTIGAPKHASEKAFFDLKTNKRVYNFCAQDAQSAQQWMDRIQSCISDA", "length": 1901, "header": "tr|A0A8V0ZNP8-1|A0A8V0ZNP8_CHICK Isoform 1 of SET binding factor 2 OS=Gallus gallus OX=9031 GN=SBF2 PE=3 SV=1 CANONICAL=A0A8V0ZNP8-1" }, "locus": { "chromosome": "5", "start_pos": 8892401, "end_pos": 8662518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051140.1", "url": "https://www.ensembl.org/id/ENSGALT00010051140.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030331.1", "url": "https://www.ensembl.org/id/ENSGALP00010030331.1" } ] } }, { "isoform_ac": "E1C7M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8/entry#E1C7M2-1", "sequence": { "sequence": "MARLADYFIVVGYDHEKTAGPAEGLGKIIQRFPQKDWEDTPFPQGIELFCQPGGWQLSKERKQPTFFVVVLTDIDSERHYCSCLTFYEAEINLQGTKETEGEEESGLIAPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLNVSLEALIANLCSCLVPASGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFRNDIHELLDVIIADLDGGTIKIPECIHLSQLPEPLLHQTQMALSLVLHPDLETADYAFPPPRTALSHTKMLDKEVRAIFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKAAFLGQRGLIENDFLTKVLNGMAFAGFVSERGPPFRACDLFDELVAFEVERIKADEGNPPKMIKHVRELAEQLFKNENPNPHIAFQKVPRPTEGSHLRVHILPFPRINECRVQELLQEGLARSQGAPSATRGDKKCVVPAGPPVVSIMEKGSTVFNSAQRLEVVRNCISFIFENKFLETEKTLPAALRALKGKAARHCLTQELGLHVKQNRAILDHQQFDYIVRMMNCALQDCSSSEEYSVAAALLPLTTAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYSNVQNQVRSLYLTAKEDNHAVHPRQKEKNSVGPDHDKTAMDLAAEQLRLWPTLNKQTQQELVQNEESTVFSQAIHFANLMVYLLVPLDTSKNKLLRASATGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENNDVANAVVRFITRFIDKVCTESGVTQDHIKGLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPTLLPGEEFVCEGLRVLLDPDGREEATGGLLGGPHILPAEGALFLTTYRIIFKGTPHDQLVGEQTVIRSFPIASVTKEKKITIQNQLQQSMQEGLQITSATFQLIKVAFDEEVSPEVVEIFKKQLMKFRYPQSIFSAFAFAAGQTAPQIILPKQKEKNTSFRTFSKSIVKGAKRAGKMTIGRQYLLKKKTGTIMEERGNRPGWNEDDDVSVSDDSDLHTSGTLKASEKSTMEQLVERACFRDYQRLGLGTISSNTSRSKMEYLRITALNRMYSLCRSYPGLLVVPQSVQDSSLQRVARCYRHNRLPVVCWRNTKNSSLLLRSGGFHGKGVVGLFKSQNTHTAAPASLESSSSIEQEKYLQALLNVISVHCKMNGSNTLTVRPTIALSPGTDRRASRMSTVFKQVVPGHLDVNLSNSFARGGVWASLRSSNRFINAQTPFIDVGARLAGKDNTTSYSSTFLQSQLLRRQAALYIFGEKSQLRGFKLDFALNCEFVPVEFSDIRQTKASFKKLLRACVPSTIPTDSEATFLKALGESEWFPQLHRIMQLGVIISELLENGSSVMVCLEDGWDITAQVVSLVQLLSDPFYRTLEGFRMLVEKEWLSFGHKFSQRSNLTLNCQGSGFAPIFLQFLDCVHQIHNQYPTEFEFNQYYLKFLAFHHISNRFKTFLLDSDYERLEHGTLFEDKGDKHNKKGVCIWECIEKMHKRSPIFFNYLYAPTEIEALKPNVSMSSLKKWDYYVEEILATGPSYDWNMVAAKCSALEEADQTDGSVSQKKRKIVWPCYDDVKKIQPDAISSLLNEIERLESKLNQNPERWQLLWERVKMNLKDDTRQDNLQRHPSGSSGMMSANLHSYQKRSLLEMPDNGLGEEQSASISPSNGVDRRATTLYNHFTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVETVIPASPTIGAPKHASEKAFFDLKTNKRVYNFCAQDAQSAQQWMDRIQSCISDA", "length": 1877, "header": "tr|E1C7M2-1|A0A8V0ZNP8_CHICK Computationally mapped isoform of SET binding factor 2 OS=Gallus gallus OX=9031 GN=SBF2 PE=3 SV=2 CANONICAL=A0A8V0ZNP8-1" }, "locus": { "chromosome": "5", "start_pos": 8892401, "end_pos": 8662518, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051141.1", "url": "https://www.ensembl.org/id/ENSGALT00010051141.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030332.1", "url": "https://www.ensembl.org/id/ENSGALP00010030332.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 479, "start_aa": "Thr", "end_pos": 479, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr479", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1T3-1", "protein_name": "SET binding factor 2", "gene_name": "Sbf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLADYFIVVGYDHEKPGPGEGLGKIIQRFPQQDWDDTPFPQGIELFCQPGGWHLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYEAEINLQGTKKEEIEGEEVSALIQPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLSVSLESLIANLCACLVPAAGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLNLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSIFKTDVHELLDVIIADLDGGTIKIPECIHLSSLPEPLLHQTQAALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLNGMAFAGFVSERGPPYRACDLFDELVAFEVERIKVEENNPLKMIKHIRELAEQLFKNENPNPHMAFQKVPRPTEGSHLRVHILPFPKINEARVQELIQENLAKNQNATPATRTEKKCIVPAGPPVVSIMDKVITVFNSAQRLEVVRNCISFIFENKTLETEKTLPAALRALKGKAARQCLTDELGLHVQQNRAILDHQQFDYIIRMMNCTLQDCSSLEEYNIAAALLPLTSAFYRRLAPGVSQFAYTCVQDHPIWTNQQFWETTFYSAVQEQVRSLYLSAKEDNHTPHQKQKELPDGQYQERTAMDLAAEQLRLWPTLSKATQQELVQHEESTVFSQAIHFANLMVNLLVPLDTSKNKLLRASAPGDWESGSNSIVTNSIAGSVAESFDTESGFEDSENNDVANSVVRFIARFIDKVCTESGVTQDHIRSLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEATGGLLGGPQLLPAEGALFLTTYRILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQLQQNMQEGLQITSASFQLIKVAFDEEVSPEVVDIFKKQLMKFRYPQSIFSTFAFAAGQTTPQIILPKQKEKNTSFRTFSKTIVKGAKKAGKMTIGRQYLLKKRTGTIVEERANRPGWNEEDDISVSDDCELPTSTTLKASEKSTMEQLVEKACFRDYQRLGLGTISGSSSRSKPEYFRVTASNRLYSLCRSYPGLLVIPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAVSTSSLESSSSIEQEKYLQALLTAVIVHQKLRGNSTLTVRPTLALSPGVWASLRSSTRLISSPTSLIDVGARLAGKDHSASFSNSTYLQNQLSKRQAALYIFGEKSQLRSSKVEFAFNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALEDSEWFPQLHRIMQLAVVVSEVLENGSSVWVCLEEGWDITTQVTSLVQLLSDPFYRTIEGFRMLVEKEWLSFGHKFSQRSSLALNSQGSGFAPIFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGDKHAKKGVCIWECIDKMHKRSPVFFNYLYSPVEIEALKPNVNVSSLKKWDYYTEETLSAGPSYDWMMLTPKHFPYEESDVAGGAGPQSQRKTVWPCYDDVTCSQPDALTRLFSEIEKLEHKLNQTPEKWHQLWEKITMDLKEEPRTDHSLRHSSRSPGIASTNVPSYQKRPALHALHRSPTEDQSTTTAPSNGVEHRAATLYSQYTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVEMVVPAGPSMGAPKYTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDRIQSCISDA", "length": 1847 }, "evidence": [ { "id": "A0A8V0ZNP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZNP8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F4G2-1", "protein_name": "Myotubularin-related protein 13 isoform X1", "gene_name": "sbf2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARLADYFTVVGYDQEKAGSGEGCGKIIQRFPKKDWDGTAFPQGVEMFCQPGGWRLSRERKPPTFFTVVLTDIDSERHFCSCLTFFEAEVNLQGSKTLEADGEEEEEEEENGLIQPAEVFAPKSLILVSRLDYPEIFRGCLGLIYTVYIDSLNFPLEGLVANLFTCFVPLAGGSQKLFSLGAGDRQLIQTPLNDSLPVSSKSIALLFQQLGIQNVLSLFCAVLTEHKVLFHSSSYQRLGEACRALETLMFPLKYSYPYIPVLPSRLLEVLSSPTPFIIGVHSMFQSEIQELLDVIIADLDGGTIKIPECIHLSQLPEPLLHNTQKALFMVLHPDLEGADNAFPPPRSAPSNLKLLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHSEPVIHFHKAAFLGQRGLIENDFLTKVLDGMAFAGFVSERGPPYRACDLFDELVALDVDCFKDEDENLVKLQKRLRELSEQLYKNENPNPHMAFQKVPRPTEGSHLRVHVVPFPMLEEERVEELIQEGLAKQHSAPVSTRPEKKCVVPAGPPVVSIMGKASSVFNSARRLEVVRTCIGFIFDNKTLETEKTLPAALRALKGKAARQCLTEELSHHVQQNRAILDHQQFDHIVRMMNCALQDCSSSEEYTVAAALLPLTTAFYRKLAAGVDQFAYTCIQEHPIWTNQQFWEATFYSEVQNQIRALYLTAPEDKPLITAKIKEPSRLSTAAGQSERTAMDLAAEQLRAWPGLSKEKQHELVKSEESTVFSQAIHYASLMVYLLVPLDTSKNKLLRSNPAADWESGSNSILTNSIAGSVAESFDTESGFEDSETSDVANSVGRFISRFIDKVCTESGVTQDHIKSLHSMIPGIVAMQMETLEVVHRESRRLPPIQKPKILRPALLPGEELVSEGLRVVLDPDGREEATGGLLGGPHILPAEGALFLTTYRIVFKGTPHDPLVGEQAVIRSFPVSTLTKEKKITIQNQLQQNMQEGLQLRSASFQLIKVAFDEEVSSEMVEIFRKHVQRIRYPSSIFSTFAFAAGQTAPQLILPKQKERNTGFRTLSKTIVKGAIKAGKITMGRQSTLKKNEKGSRMTWHEDDDISISDDGEPPSSNTLKASEKSTMEQLVERACFRDYQRLGLGTISANSTRLKSGEQFRVTAVNRLYSLCRSYPGLLVIPHTVQDSSLQKVSRCYRHNRLPVVCWKHPRTKAVLLRSGGFHSKSVVGLFKSQNPSSAAPTSSDTSSSLEQEKYLQAILSSIPIYFKPNGSNTLTNRSLIGLSPASERRASRIPKMAPVHLDISFTNSFTRGVLGYRDKLFTHSNQKASAKGRIHNQGVWASLRSSSRFIQHPAVGDVGARLAGKDLAPPTGIENLQAQLLKHQAALYIFGEKSHFRGLKLDPALNCELVPVEFADTRQVKASFKKLLRACAPSAMSSDTEDSFLKALEESEWMLQIHKLLQLAVVAVELLDSGSSVLVSLEEGWDITTQVVSLTQVLSDPFYRTLEGFQVLLEKEWLSFGHKFSQRGNLNPNSQGSGFTPIFLQFLDCVHQVHNQYPLEFEFNQYYLKFLAYHYVSNRFKNFLLDSDYERLEHGTLFEDKGEKQSKRGICIWECINRMHRKGPLFFNYLYSPSETEPVLKPLISIPNLTTWEFYTGETLSTGPSYDWCMLTVRSQSMEESDTIATTKRRIVWPCYSSVSRAQPDAISKLLADIEKLEGEQGQHSEPWHTTLEKAIDGIQEDLKQEGNLRKQSLSISGLVPTSNLQAYQRRSMLHLPDGGLGEDNSPAAVNGVHRRAATLYNQFTPKNEDNRSFEGILYKRGALLKAWKARWFVLDTTKHQLRYYETDEDTSCRGFIDLADVESVLIAAPTIGAPKHISEKAFFDLKTNKRVYNFCAADAPSAQLWIDKIQSCISDA", "length": 1898 }, "evidence": [ { "id": "A0A8V0ZNP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZNP8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PXF8-1", "protein_name": "Myotubularin-related protein 13", "gene_name": "Sbf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLADYFIVVGYDHEKPAGPGEGLGKIIQRFPQQDWDDTPFPQGIELFCQPGGWHLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYEAEINLQGTKKEEIEGEEVSGLIQPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSMSVSLESLIANLCACLVPAAGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLNLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSIFKTDVHELLDVIIADLDGGTIKIPECIHLSSLPEPLLHQTQSALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLNGMAFAGFVSERGPPYRACDLFDELVAFEVERIKVEEKNPLKMIKHIRELAEQLFKNENPNPHMAFQKVPRPTEGSHLRVHILPFPKINEARVQELIQENLAKNQNAPPATRIEKKCVVPAGPPVVSIMEKVITVFNSAQRLEVVRNCISFIFENKTLETEKTLPAALRALKGKAARQCLTDELGLHVQQNRAILDHQQFDYIIRMMNCTLQDCSSLEEYNIAAALLPLTSAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYNAVQEQVRSLYLSAKDDNHIPHLKQKLPDGQHQEKTAMDLAAEQLRLWPTLSKSTQQELVQHEESTVFSQAIHFANLMVNLLVPLDTSKNKLLRASAPGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENSDVANSVVRFIARFIDKVCTESGVTQDHIRSLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEATGGLLGGPQLLPAEGALFLTTYRILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQLQQSVQEGLQITSASFQLIKVAFDEEVSPEVVDIFKKQLMKFRYPQSIFSTFAFAAGQTTPQIILPKQKEKNTSFRTFSKTIVKGAKKAGKMTIGRQYLLKKRTGTIVEERVNRPGWNEEDDISVSDDSELPTSTTLKASEKSTMEQLVEKACFRDYQRLGLGTISGNSSRSKPEYFRVTASNRLYSLCRSYPGLLVIPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAVSTSSLESSSSIEQEKYLQALLTAVIVHQKLRGSSTLTVRPALALSPVHGYRDKSFTQSNPKSSAKEPVHNQGVWASLRSSTRLISSPTSFIDVGARLAGKDHSASFSNSTYLQNQLLKRQAALYIFGEKSQLRSSKVEFAFNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAVVVSEVLENGSSVWVCLEEGWDITTQVTSLAQLLSDPFYRTIAGFRTLVEKEWLSFGHKFSQRSSLALNSQGGGFAPIFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGDKHAKKGVCIWECIDKMHTRSPIFFNYLYSPVEVEALKPNVNVSSLKKWDYYTEETLSAGPSYDWMMLTPKHFPYEESDVAGGAGPQSQRKTVWPCYDDVTCSQPDALTRLFSEIEKLEHKLNQTPERWHQLWEKVTTDLKEEPRTAHSLRHSAGSPGIASTNVPSYQKRPALHPLHRGLGEDQSTTTAPSNGVEHRAATLYSQYTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVEMVIPAGPSMGAPKYTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDRIQSCISDA", "length": 1872 }, "evidence": [ { "id": "A0A8V0ZNP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZNP8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86WG5-1", "protein_name": "Myotubularin-related protein 13", "gene_name": "SBF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARLADYFIVVGYDHEKPGSGEGLGKIIQRFPQKDWDDTPFPQGIELFCQPGGWQLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYEAEINLQGTKKEEIEGEAKVSGLIQPAEVFAPKSLVLVSRLYYPEIFRACLGLIYTVYVDSLNVSLESLIANLCACLVPAAGGSQKLFSLGAGDRQLIQTPLHDSLPITGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFKTDVHELLDVIIADLDGGTIKIPECIHLSSLPEPLLHQTQSALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLSGMAFAGFVSERGPPYRSCDLFDELVAFEVERIKVEENNPVKMIKHVRELAEQLFKNENPNPHMAFQKVPRPTEGSHLRVHILPFPEINEARVQELIQENVAKNQNAPPATRIEKKCVVPAGPPVVSIMDKVTTVFNSAQRLEVVRNCISFIFENKILETEKTLPAALRALKGKAARQCLTDELGLHVQQNRAILDHQQFDYIIRMMNCTLQDCSSLEEYNIAAALLPLTSAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYNAVQEQVRSLYLSAKEDNHAPHLKQKDKLPDDHYQEKTAMDLAAEQLRLWPTLSKSTQQELVQHEESTVFSQAIHFANLMVNLLVPLDTSKNKLLRTSAPGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENTDIANSVVRFITRFIDKVCTESGVTQDHIKSLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEATGGLLGGPQLLPAEGALFLTTYRILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQLQQNMQEGLQITSASFQLIKVAFDEEVSPEVVEIFKKQLMKFRYPQSIFSTFAFAAGQTTPQIILPKQKEKNTSFRTFSKTIVKGAKRAGKMTIGRQYLLKKKTGTIVEERVNRPGWNEDDDVSVSDESELPTSTTLKASEKSTMEQLVEKACFRDYQRLGLGTISGSSSRSRPEYFRITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAAPTSSLESSSSIEQEKYLQALLNAVSVHQKLRGNSTLTVRPAFALSPGVWASLRSSTRLISSPTSFIDVGARLAGKDHSASFSNSSYLQNQLLKRQAALYIFGEKSQLRNFKVEFALNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAVVVSEVLENGSSVLVCLEEGWDITAQVTSLVQLLSDPFYRTLEGFQMLVEKEWLSFGHKFSQRSSLTLNCQGSGFAPVFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGEKHAKKGVCIWECIDRMHKRSPIFFNYLYSPLEIEALKPNVNVSSLKKWDYYIEETLSTGPSYDWMMLTPKHFPSEDSDLAGEAGPRSQRRTVWPCYDDVSCTQPDALTSLFSEIEKLEHKLNQAPEKWQQLWERVTVDLKEEPRTDRSQRHLSRSPGIVSTNLPSYQKRSLLHLPDSSMGEEQNSSISPSNGVERRAATLYSQYTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVEMVIPAGPSMGAPKHTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDKIQSCISDA", "length": 1849 }, "evidence": [ { "id": "A0A8V0ZNP8", "url": "https://omabrowser.org/oma/group/A0A8V0ZNP8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" } ], "pmid": "" }, { "name": "vacuolar membrane", "id": "GO:0005774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005774", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" } ], "pmid": "" }, { "name": "phosphatase regulator activity", "id": "GO:0019208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019208", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1031, "end_pos": 1033, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1127, "end_pos": 1129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1188, "end_pos": 1190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1246, "end_pos": 1248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1285, "end_pos": 1287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1348, "end_pos": 1350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1454, "end_pos": 1456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1510, "end_pos": 1512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1623, "end_pos": 1625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1795, "end_pos": 1797, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 1106, "end_pos": 1636, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZNP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 1795, "end_pos": 1899, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZNP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP8" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 425, "start_aa": "Tyr", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 479 ], "snv_sites": [], 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"common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PTRF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB6", "locus": { "chromosome": "27", "start_pos": 4911093, "end_pos": 4928429, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021165", "url": "https://www.ensembl.org/id/ENSGALG00010021165" } ] } } ], "crossref": [ { "id": "A0A8V0ZPB6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPB6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR026752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB12", "url": "https://www.orthodb.org/?gene=A0A8V0ZB12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGW9", "url": "https://www.orthodb.org/?gene=A0A8V0ZGW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": 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CANONICAL=A0A8V0ZPB6-1" }, "locus": { "chromosome": "27", "start_pos": 4927853, "end_pos": 4918707, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051333.1", "url": "https://www.ensembl.org/id/ENSGALT00010051333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030524.1", "url": "https://www.ensembl.org/id/ENSGALP00010030524.1" } ] } }, { "isoform_ac": "A0A8V0ZIB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB6/entry#A0A8V0ZIB3-1", "sequence": { "sequence": "MEDTTLQIIEPPTASEASEEQMPEEPIKSDQINGVMVLTLLDKIIGAVDQIQLTQTQLEERQQEMDSAVVSIQGELTKLTKAHTTTSNTVNKMLEKVRKVSVNVKTVRQNLEKQAGQIKKLEANEAELLKRRNFKVMIYQDEVKLPSKLSISKSLKEGEGEEVPAGEDHAEEDHIQLSSDEEVEIEEIIEESRAERIKRSGMKRVDDFKKAFSKEKMEKTKLKTKENLEKTRHNLEKTRHNLEKRMNKLGTKIVTNERREKMKTSRDKLRKSFTPDHTIYARSKTAVYKVPPFTFHVKKIREGEVEVKATELVEVGGEEGENSDLMRGESPEMHTLLEITEESDAVLVDKSDSE", "length": 354, "header": "tr|A0A8V0ZIB3-1|A0A8V0ZPB6_CHICK Computationally mapped isoform of Polymerase I and transcript release factor OS=Gallus gallus OX=9031 GN=PTRF PE=1 SV=1 CANONICAL=A0A8V0ZPB6-1" }, "locus": { "chromosome": "27", "start_pos": 4925499, "end_pos": 4912792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051344.1", "url": "https://www.ensembl.org/id/ENSGALT00010051344.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030535.1", "url": "https://www.ensembl.org/id/ENSGALP00010030535.1" } ] } }, { "isoform_ac": "A0A8V0ZP67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB6/entry#A0A8V0ZP67-1", "sequence": { "sequence": "MEDTTLQIIEPPTASEASEEQMPEEPIKSDQINGVMVLTLLDKIIGAVDQIQLTQTQLEERQQEMDSAVVSIQGELTKLTKAHTTTSNTVNKMLEKVRKVSVNVKTVRQNLEKQAGQIKKLEANEAELLKRRNFKVMIYQKQILLSSS", "length": 148, "header": "tr|A0A8V0ZP67-1|A0A8V0ZP67_CHICK Computationally mapped isoform of Polymerase I and transcript release factor OS=Gallus gallus OX=9031 GN=PTRF PE=1 SV=1 CANONICAL=A0A8V0ZPB6-1" }, "locus": { "chromosome": "27", "start_pos": 4925499, "end_pos": 4919137, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051302.1", "url": "https://www.ensembl.org/id/ENSGALT00010051302.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030497.1", "url": "https://www.ensembl.org/id/ENSGALP00010030497.1" } ] } }, { "isoform_ac": "A0A8V0ZPB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB6/entry#A0A8V0ZPB6-1", "sequence": { "sequence": "METNPLALMCPNQWERKATVCHLLAFPVALSLGSPSQDSSAIMEDTTLQIIEPPTASEASEEQMPEEPIKSDQINGVMVLTLLDKIIGAVDQIQLTQTQLEERQQEMDSAVVSIQGELTKLTKAHTTTSNTVNKMLEKVRKVSVNVKTVRQNLEKQAGQIKKLEANEAELLKRRNFKVMIYQDEVKLPSKLSISKSLKEGEKQEKEGEGEEVPAGEDHAEEDHIQLSSDEEVEIEEIIEESRAERIKRSGMKRVDDFKKAFSKEKMEKTKLKTKENLEKTRHNLEKTRHNLEKRMNKLGTKIVTNERREKMKTSRDKLRKSFTPDHTIYARSKTAVYKVPPFTFHVKKIREGEVEVKATELVEVGGEEGENSDLMRGESPEMHTLLEITEESDAVLVDKSDSE", "length": 403, "header": "tr|A0A8V0ZPB6-1|A0A8V0ZPB6_CHICK Isoform 1 of Polymerase I and transcript release factor OS=Gallus gallus OX=9031 GN=PTRF PE=1 SV=1 CANONICAL=A0A8V0ZPB6-1" }, "locus": { "chromosome": "27", "start_pos": 4927853, "end_pos": 4912792, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051357.1", "url": "https://www.ensembl.org/id/ENSGALT00010051357.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030548.1", "url": "https://www.ensembl.org/id/ENSGALP00010030548.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-73863", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73863", "resource": "Reactome", "description": "RNA Polymerase I Transcription Termination" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013026", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013026", "resource": "Reactome", "description": "RHOB GTPase 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"evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB6" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase I promoter", "id": "GO:0006361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006361", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB6" } ], "pmid": "" }, { "name": "termination of RNA polymerase I transcription", "id": "GO:0006363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006363", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPB6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZP55-1", "uniprot_ac": "A0A8V0ZP55", "uniprot_id": "A0A8V0ZP55_CHICK", "mass": { "chemical_mass": 68516.0, "monoisotopic_mass": 68516.0 }, "refseq": { "ac": "XP_015149849", "name": "equilibrative nucleoside transporter 4 isoform X7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149849" }, "gene_names": [ { "name": "SLC29A4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ] }, { "name": "SLC29A4", "type": "synonym", "evidence": [ { "id": "XP_015149849", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149849" } ] } ], "protein_names": [ { "name": "Equilibrative nucleoside transporter 4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 29 member 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZP55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55/entry#names_and_taxonomy" } ] }, { "name": "equilibrative nucleoside transporter 4 isoform X7", "type": "synonym", "evidence": [ { "id": "XP_015149849", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149849" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149849.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149849", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149849" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC29A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55", "locus": { "chromosome": "14", "start_pos": 4093038, "end_pos": 4086920, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021172", "url": "https://www.ensembl.org/id/ENSGALG00010021172" } ] } } ], "crossref": [ { "id": "A0A8V0ZP55", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP55", "database": "AlphaFoldDB", "categories": [] }, { "id": "425593", "url": "https://www.ncbi.nlm.nih.gov/gene/425593", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB55", "url": "https://www.orthodb.org/?gene=A0A8V0ZB55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGT9", "url": "https://www.orthodb.org/?gene=A0A8V0ZGT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZGU4", "url": "https://www.orthodb.org/?gene=A0A8V0ZGU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI74", "url": "https://www.orthodb.org/?gene=A0A8V0ZI74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI82", "url": "https://www.orthodb.org/?gene=A0A8V0ZI82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP55", "url": "https://www.orthodb.org/?gene=A0A8V0ZP55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10332:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10332:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01733", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01733", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-83936", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-83936", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015149849", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149849", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGT9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI74", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFSISACTCRLGVRSPPHPGSGERLQNLRVAASTASRGKSRLITLIDLFFSLPCLPRPAASSEVSLRRAVGGQRARGRLASSDWHRPSTMGSVGTERFKELSPMGTPEGNVVMSFSFDSYQLEEDELQRGSQAKGVLTFMEPASEDPEPQDRYHGIYLAMLLAGVGFLLPYNSFITDVDYLHHKYPGTSIVFDMSLTYILVALVAVILNNALVELLSLHTRISVGYLFALGPLLFVSICDVWLELFTRRQAYAINLVAVGVVAFGCTVQQSSFYGYTGLLPKRYTQGVMTGESTAGVIISLSRIFTKLLLSDEKENTVIFFFISIGMELTCFILHLLVKRTRFVRYYTSCPRKGHPERRGATDHGMGYRIHHDVTAEDIRFEDQLQGQLGSPRGSPGPEAELAGSGTYMRFDVPRPKIKRSWPSFRAMLLHRYVVSRLIWAYMLSIAMTYFITLCLFPGLESEIHNCTLGEWLPILIMAIFNLSDFVGKILAALPYDWRGTHLLVYSCLRVVFIPLFIMCVYPNGQPTFGHPAWPCVFSLLMGITNGYFGSVPMILAAGKVSPEQRELAGNTMTVSYMTGLTLGSAVAYFAYSLTSTSHSSCFYTETSNGSFLGGY", "length": 617, "header": "tr|A0A8V0ZP55-1|A0A8V0ZP55_CHICK Isoform 1 of Equilibrative nucleoside transporter 4 OS=Gallus gallus OX=9031 GN=SLC29A4 PE=3 SV=1 CANONICAL=A0A8V0ZP55-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZB55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55/entry#A0A8V0ZB55-1", "sequence": { "sequence": "MGSVGTERFKELSPMGTPEGNVVMSFSFDSYQLEEDELQRGSQAKGVLTFMEPASEDPEPQDRYHGIYLAMLLAGVGFLLPYNSFITDVDYLHHKYPGTSIVFDMSLTYILVALVAVILNNALVELLSLHTRISVGYLFALGPLLFVSICDVWLELFTRRQAYAINLVAVGVVAFGCTVQQSSFYGYTGLLPKRYTQGVMTGESTAGVIISLSRIFTKLLLSDEKENTVIFFFISIGMELTCFILHLLVKRTRFVRYYTSCPRKGHPERRGATDHGMGYRIHHDVTAEDIRFEDQLQGQLGSPRGSPGPEAELAGSGTYMRFDVPRPKIKRSWPSFRAMLLHRYVVSRLIWAYMLSIAMTYFITLCLFPGLESEIHNCTLGEWLPILIMAIFNLSDFVGKILAALPYDWRGTHLLVYSCLRVVFIPLFIMCVYPNGQPTFGHPAWPCVFSLLMGITNGYFGSVPMILAAGKVSPEQRELAGNTMTVSYMTGLTLGSAVAYFAYSLTSTSHSGSWALCRANPWADGPQCCWSQCSWGTPPGQWWREGSSPV", "length": 550, "header": "tr|A0A8V0ZB55-1|A0A8V0ZP55_CHICK Computationally mapped isoform of Equilibrative nucleoside transporter 4 OS=Gallus gallus OX=9031 GN=SLC29A4 PE=3 SV=1 CANONICAL=A0A8V0ZP55-1" }, "locus": { "chromosome": "14", "start_pos": 4092282, "end_pos": 4088627, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051311.1", "url": "https://www.ensembl.org/id/ENSGALT00010051311.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030502.1", "url": "https://www.ensembl.org/id/ENSGALP00010030502.1" } ] } }, { "isoform_ac": "A0A8V0ZGT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55/entry#A0A8V0ZGT9-1", "sequence": { "sequence": "MGSVGTERFKELSPMGTPEGNVVMSFSFDSYQLEEDELQRGSQAKGVLTFMEPASEDPEPQDRYHGIYLAMLLAGVGFLLPYNSFITDVDYLHHKYPGTSIVFDMSLTYILVALVAVILNNALVELLSLHTRISATSLLWAPSSSSASATSGWSSSPGGKPMPSTWWLLGWWPLAAQQSSFYGYTGLLPKRYTQGVMTGESTAGVIISLSRIFTKLLLSDEKENTVIFFFISIGMELTCFILHLLVKRTRFVRYYTSCPRKGHPERRGATDHGMGYRIHHDVTAEDIRFEDQLQGQLGSPRGSPGPEAELAGSGTYMRFDVPRPKIKRSWPSFRAMLLHRYVVSRLIWAYMLSIAMTYFITLCLFPGLESEIHNCTLGEWLPILIMAIFNLSDFVGKILAALPYDWRGTHLLVYSCLRVVFIPLFIMCVYPNGQPTFGHPAWPCVFSLLMGITNGYFGSVPMILAAGKVSPEQRELAGNTMTVSYMTGLTLGSAVAYFAYSLTSTSHSSCFYTETSNGSFLGGY", "length": 524, "header": "tr|A0A8V0ZGT9-1|A0A8V0ZP55_CHICK Computationally mapped isoform of Equilibrative nucleoside transporter 4 OS=Gallus gallus OX=9031 GN=SLC29A4 PE=3 SV=1 CANONICAL=A0A8V0ZP55-1" }, "locus": { "chromosome": "14", "start_pos": 4092083, "end_pos": 4088627, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051303.1", "url": "https://www.ensembl.org/id/ENSGALT00010051303.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030493.1", "url": "https://www.ensembl.org/id/ENSGALP00010030493.1" } ] } }, { "isoform_ac": "A0A8V0ZGU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55/entry#A0A8V0ZGU4-1", "sequence": { "sequence": "MGSVGTERFKELSPMGTPEGNVVMSFSFDSYQLEEDELQRGSQAKGVLTFMEPASEDPEPQDRYHGIYLAMLLAGVGFLLPYNSFITDVDYLHHKYPGTSIVFDMSLTYILVALVAVILNNALVELLSLHTRISVGYLFALGPLLFVSICDVWLELFTRRQAYAINLVAVGVVAFGCTGTAGVIISLSRIFTKLLLSDEKENTVIFFFISIGMELTCFILHLLVKRTRFVRYYTSCPRKGHPERRGATDHGMGYRIHHDVTAEDIRFEDQLQGQLGSPRGSPGPEAELAGSGTYMRFDVPRPKIKRSWPSFRAMLLHRYVVSRLIWAYMLSIAMTYFITLCLFPGLESEIHNCTLGEWLPILIMAIFNLSDFVGKILAALPYDWRGTHLLVYSCLRVVFIPLFIMCVYPNGQPTFGHPAWPCVFSLLMGITNGYFGSVPMILAAGKVSPEQRELAGNTMTVSYMTGLTLGSAVAYFAYSLTSTSHSSCFYTETSNGSFLGGY", "length": 502, "header": "tr|A0A8V0ZGU4-1|A0A8V0ZP55_CHICK Computationally mapped isoform of Equilibrative nucleoside transporter 4 OS=Gallus gallus OX=9031 GN=SLC29A4 PE=3 SV=1 CANONICAL=A0A8V0ZP55-1" }, "locus": { "chromosome": "14", "start_pos": 4092083, "end_pos": 4088627, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051307.1", "url": "https://www.ensembl.org/id/ENSGALT00010051307.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030498.1", "url": "https://www.ensembl.org/id/ENSGALP00010030498.1" } ] } }, { "isoform_ac": "A0A8V0ZI74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55/entry#A0A8V0ZI74-1", "sequence": { "sequence": "MPGGGLGARFGMRPSTMGSVGTERFKELSPMGTPEGNVVMSFSFDSYQLEEDELQRGSQAKGVLTFMEPASEDPEPQDRYHGIYLAMLLAGVGFLLPYNSFITDVDYLHHKYPGTSIVFDMSLTYILVALVAVILNNALVELLSLHTRISVGYLFALGPLLFVSICDVWLELFTRRQAYAINLVAVGVVAFGCTVQQSSFYGYTGLLPKRYTQGVMTGESTAGVIISLSRIFTKLLLSDEKENTVIFFFISIGMELTCFILHLLVKRTRFVRYYTSCPRKGHPERRGATDHGMGYRIHHDVTAEDIRFEDQLQGQLGSPRGSPGPEAELAGSGTYMRFDVPRPKIKRSWPSFRAMLLHRYVVSRLIWAYMLSIAMTYFITLCLFPGLESEIHNCTLGEWLPILIMAIFNLSDFVGKILAALPYDWRGTHLLVYSCLRVVFIPLFIMCVYPNGQPTFGHPAWPCVFSLLMGITNGYFGSVPMILAAGKVSPEQRELAGNTMTVSYMTGLTLGSAVAYFAYSLTSTSHSSCFYTETSNGSFLGGY", "length": 543, "header": "tr|A0A8V0ZI74-1|A0A8V0ZP55_CHICK Computationally mapped isoform of Equilibrative nucleoside transporter 4 OS=Gallus gallus OX=9031 GN=SLC29A4 PE=3 SV=1 CANONICAL=A0A8V0ZP55-1" }, "locus": { "chromosome": "14", "start_pos": 4092083, "end_pos": 4088477, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051299.1", "url": "https://www.ensembl.org/id/ENSGALT00010051299.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030490.1", "url": "https://www.ensembl.org/id/ENSGALP00010030490.1" } ] } }, { "isoform_ac": "A0A8V0ZI82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55/entry#A0A8V0ZI82-1", "sequence": { "sequence": "MLDHLTSGGEEKAPCNGSTACVLNETRPSTMGSVGTERFKELSPMGTPEGNVVMSFSFDSYQLEEDELQRGSQAKGVLTFMEPASEDPEPQDRYHGIYLAMLLAGVGFLLPYNSFITDVDYLHHKYPGTSIVFDMSLTYILVALVAVILNNALVELLSLHTRISVGELRSPCSWAAPAPHCPLPTSISPPPGYLFALGPLLFVSICDVWLELFTRRQAYAINLVAVGVVAFGCTVQQSSFYGYTGLLPKRYTQGVMTGESTAGVIISLSRIFTKLLLSDEKENTVIFFFISIGMELTCFILHLLVKRTRFVRYYTSCPRKGHPERRGATDHGMGYRIHHDVTAEDIRFEDQLQGQLGSPRGSPGPEAELAGSGTYMRFDVPRPKIKRSWPSFRAMLLHRYVVSRLIWAYMLSIAMTYFITLCLFPGLESEIHNCTLGEWLPILIMAIFNLSDFVGKILAALPYDWRGTHLLVYSCLRVVFIPLFIMCVYPNGQPTFGHPAWPCVFSLLMGITNGYFGSVPMILAAGKVSPEQRELAGRAAPPRGCHAGWPWRVTPSVRLRREHHDRVLHDGLDAGLSRGLFCLQPHQYVPQ", "length": 591, "header": "tr|A0A8V0ZI82-1|A0A8V0ZP55_CHICK Computationally mapped isoform of Equilibrative nucleoside transporter 4 OS=Gallus gallus OX=9031 GN=SLC29A4 PE=3 SV=1 CANONICAL=A0A8V0ZP55-1" }, "locus": { "chromosome": "14", "start_pos": 4092034, "end_pos": 4086935, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051314.1", "url": "https://www.ensembl.org/id/ENSGALT00010051314.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030505.1", "url": "https://www.ensembl.org/id/ENSGALP00010030505.1" } ] } }, { "isoform_ac": "A0A8V0ZP55-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55/entry#A0A8V0ZP55-1", "sequence": { "sequence": "MRFSISACTCRLGVRSPPHPGSGERLQNLRVAASTASRGKSRLITLIDLFFSLPCLPRPAASSEVSLRRAVGGQRARGRLASSDWHRPSTMGSVGTERFKELSPMGTPEGNVVMSFSFDSYQLEEDELQRGSQAKGVLTFMEPASEDPEPQDRYHGIYLAMLLAGVGFLLPYNSFITDVDYLHHKYPGTSIVFDMSLTYILVALVAVILNNALVELLSLHTRISVGYLFALGPLLFVSICDVWLELFTRRQAYAINLVAVGVVAFGCTVQQSSFYGYTGLLPKRYTQGVMTGESTAGVIISLSRIFTKLLLSDEKENTVIFFFISIGMELTCFILHLLVKRTRFVRYYTSCPRKGHPERRGATDHGMGYRIHHDVTAEDIRFEDQLQGQLGSPRGSPGPEAELAGSGTYMRFDVPRPKIKRSWPSFRAMLLHRYVVSRLIWAYMLSIAMTYFITLCLFPGLESEIHNCTLGEWLPILIMAIFNLSDFVGKILAALPYDWRGTHLLVYSCLRVVFIPLFIMCVYPNGQPTFGHPAWPCVFSLLMGITNGYFGSVPMILAAGKVSPEQRELAGNTMTVSYMTGLTLGSAVAYFAYSLTSTSHSSCFYTETSNGSFLGGY", "length": 617, "header": "tr|A0A8V0ZP55-1|A0A8V0ZP55_CHICK Isoform 1 of Equilibrative nucleoside transporter 4 OS=Gallus gallus OX=9031 GN=SLC29A4 PE=3 SV=1 CANONICAL=A0A8V0ZP55-1" }, "locus": { "chromosome": "14", "start_pos": 4092083, "end_pos": 4088161, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051296.1", "url": "https://www.ensembl.org/id/ENSGALT00010051296.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030487.1", "url": "https://www.ensembl.org/id/ENSGALP00010030487.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-83936", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-83936", "resource": "Reactome", "description": "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "neurotransmitter transmembrane transporter activity", "id": "GO:0005326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005326", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "nucleoside transmembrane transporter activity", "id": "GO:0005337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005337", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "monoamine transmembrane transporter activity", "id": "GO:0008504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008504", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "monoatomic cation transmembrane transporter activity", "id": "GO:0008324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "efflux transmembrane transporter activity", "id": "GO:0015562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015562", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "dopamine uptake", "id": "GO:0090494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "serotonin uptake", "id": "GO:0051610", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051610", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "xenobiotic transport", "id": "GO:0042908", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042908", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "norepinephrine uptake", "id": "GO:0051620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051620", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "adenosine transport", "id": "GO:0032238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032238", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "histamine uptake", "id": "GO:0051615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "epinephrine transport", "id": "GO:0048241", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048241", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "export across plasma membrane", "id": "GO:0140115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140115", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "cellular detoxification", "id": "GO:1990748", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990748", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" }, { "name": "epinephrine uptake", "id": "GO:0051625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP55", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 467, "end_pos": 469 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 610, "end_pos": 612 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPX4-1", "uniprot_ac": "A0A8V0ZPX4", "uniprot_id": "A0A8V0ZPX4_CHICK", "mass": { "chemical_mass": 152816.0, "monoisotopic_mass": 152816.0 }, "refseq": { "ac": "NP_001292131", "name": "collagen alpha-1(XVII) chain", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292131" }, "gene_names": [ { "name": "COL17A1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPX4", "database": 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The reference sequence was derived from JAENSK010000232.1. On Sep 30, 2021 this sequence version replaced NP_001292131.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292131", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292131" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "COL17A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4", "locus": { "chromosome": "6", "start_pos": 24919985, "end_pos": 24980154, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021287", "url": "https://www.ensembl.org/id/ENSGALG00010021287" } ] } } ], "crossref": [ { "id": "396503", "url": "https://www.ncbi.nlm.nih.gov/gene/396503", 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"MDSVTKKTRQDGSEVTERLITETVTTRLTSLPPKGGSSSGLKTSSHTGGSGVEKRSYTHSSGYVTSSGSGRLNSSSSGYRQTQSPSSTLTKSPGSTFERKTYVNRHATYEGSSSANSSPEFPRKEFASASTRGRSQSRESEIRVRLQSASPSGRWTELDDVKRLLKGSRSASCSPTRSSSSTLPIPKKAVVETKMVTESSQSVSGTYDTTILNTTLPPYTWSSTLPAGSSLGGYHNSMGQSSSLINAMSHSTGSVFGVPNNLAPSSHALNTGLSTSSTVFGVQNNLSPSSSALNASAASAAYGMKNTSQTNTMNSTGVSASAGGTILSSQGDDFLHKDCKFLLLEKENAPAKKEMELLVMTKDSGKVFSASSTGLNGGSFAEDTLKKEKQGLSSYAADTGLKSDANGGLKSAPTRDKATYAEIQNGGAGGAIGSAPSWCPCGSCCSWWKWLLGLLLAWLLLLGLLFGLIALAEEVRKLKSRVDNLEKINHSFLTVNQGNPYLEKDVSKVDFLHGVAPSSTFPFENEESVWLMVKSRLNKEIERGYFRGERGEPGMKGDMGLQGPKGDRGLPGVPGIPGPVGHQGPEGPKGQKGSMGDPGMEGPMGQRGREGLPGPRGEPGPPGFGEKGDRGAAGPPGPPGPPGSAGLKGPMGSPGPQGPPGPPGLQGFRGEAGLPGAKGEKGATGPPGPKGDQGEKGARGMTGEQGSRGIPGPPGEPGAKGPAGQAGRDGQPGERGEPGLMGMPGARGPPGPSGDTGEPGLTGPQGPPGLPGNPGRPGAKGEPGAPGKVISAEGSSTIALPGPPGPPGPIGPTGPPGVPGPVGPAGLPGQQGPRGEKGSAGEVVIETIKTEVSSLASQMLSDLQGRAGPPGPPGPPGESVQGLPGPRGPPGLPGPSGPPGRPGSSVSTSETFVSGPPGPPGPPGPKGDQGEPGPRGFTGEPGEPGLPGFSSHGGTVTMQGPPGPPGPPGPKGDAGVPGAPGIPGTSRGGSRQIQGPPGPPGPPGPPGPGGSSSQEIQQYVADYLKSDNVRHYLTGVQGPPGPPGPPGILTTADGKNFDFAELATRVMSYVTSSSDHYQSFASSVSTTSVLYQELLNMLQREEIRQYLVGPRGPPGPPGPGVDGMSLSLDYDELTRRFISYLTSSGMSIGLPGPPGPPGTPGISYSELTAYLRNSEFSGLVGPPGPAGPPGPPGIPGSSGTSLEDISAYLQSVGYSSISGIQGPPGPPGPPGPPGFSGTGLLSYADITHSDEFRSELIQYLKSDEVRSYISGPPGPPGPRGPPGPKGDSGLVAGSMSSLYHDSLASERLHGGSIGAEGSHGGSLGASSSYGSSMSSSMSSYSASMGSDGSYGASVGSDGSFDGLLTAEESHRRSAGPGRSYSSSFTGSLDYNELARHVSENLQSRGILQDLMSYTGQGPPGPPGPPGPPGISRVFAAYGNVTEDLMDFFRTHGTVRGPPGEKGERGYPGPKGDPGPMGPPGRHGQRGPKGEKGEKGEQMYSGRRRRRSVGV", "length": 1510, "header": "tr|A0A8V0ZPX4-1|A0A8V0ZPX4_CHICK Isoform 1 of Collagen alpha-1(XVII) chain OS=Gallus gallus OX=9031 GN=COL17A1 PE=4 SV=1 CANONICAL=A0A8V0ZPX4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZC30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4/entry#A0A8V0ZC30-1", "sequence": { "sequence": "MDSVTKKTRQDGSEVTERQGGSSSGLKTSSHTGGSGVEKRSYTHSSGYVTSSGSGRLNSSSSGYRQTQSPSSTLTKSPGSTFERKTYVNRHATYEGSSSANSSPEFPRKEFASASTRGRSQSRESEIRVRLQSASPSGRWTELDDVKRLLKGSRSASCSPTRSSSSTLPIPKKAVVETKMVTESSQSVSGTYDTTILNTTLPPYTWSSTLPAGSSLGGYHNSMGQSSSLINAMSHSTGSVFGVPNNLAPSSHALNTGLSTSSTVFGVQNNLSPSSSALNASAASAAYGMKNTSQTNTMNSTGVSASAGGTILSSQGDDFLHKDCKFLLLEKENAPAKKEMELLVMTKDSGKVFSASSTGLNGGSFAEDTLKKEKQGLSSYAADTGLKSDANGGLKSAPTRDKATYAEIQNGGAGGAIGSAPSWCPCGSCCSWWKWLLGLLLAWLLLLGLLFGLIALAEEVRKLKSRVDNLEKINHSFLTVNQGNPYLEKDVSKVDFLHGVAPSSTFPFENEESVWLMVKSRLNKEIERGYFRGERGEPGMKGDMGLQGPKGDRGLPGVPGIPGPVGHQGPEGPKGQKGSMGDPGMEGPMGQRGREGLPGPRGEPGPPGFGEKGDRGAAGPPGPPGPPGSAGLKGPMGSPGPQGPPGPPGLQGFRGEAGLPGAKGEKGATGPPGPKGDQGEKGARGMTGEQGSRGIPGPPGEPGAKGPAGQAGRDGQPGERGEPGLMGMPGARGPPGPSGDTGEPGLTGPQGPPGLPGNPGRPGAKGEPGAPGKVISAEGSSTIALPGPPGPPGPIGPTGPPGVPGPVGPAGLPGQQGPRGEKGSAGEVVIETIKTEVSSLASQMLSDLQGRAGPPGPPGPPGESVQGLPGPRGPPGLPGPSGPPGRPGSSVSTSETFVSGPPGPPGPPGPKGDQGEPGPRGFTGEPGEPGLPGFSSHGGTVTMQGPPGPPGPPGPKGDAGVPGAPGIPGTSRGGSRQIQGPPGPPGPPGPPGPGGSSSQEIQQYVADYLKSDNVRHYLTGVQGPPGPPGPPGILTTADGKNFDFAELATRVMSYVTSSSDHYQSFASSVSTTSVLYQELLNMLQREEIRQYLVGPRGPPGPPGPGVDGMSLSLDYDELTRRFISYLTSSGMSIGLPGPPGPPGTPGISYSELTAYLRNSEFSGLVGPPGPAGPPGPPGIPGSSGTSLEDISAYLQSVGYSSISGIQGPPGPPGPPGPPGFSGTGLLSYADITHSDEFRSELIQYLKSDEVRSYISGPPGPPGPRGPPGPKGDSGLVAGSMSSLYHDSLASERLHGGSIGAEGSHGGSLGASSSYGSSMSSSMSSYSASMGSDGSYGASVGSDGSFDGLLTAEESHRRSAGPGRSYSSSFTGSLDYNELARHVSENLQSRGILQDLMSYTGQGPPGPPGPPGPPGISRVFAAYGNVTEDLMDFFRTHGTVRGPPGEKGERGYPGPKGDPGPMGPPGRHGQRGPKGEKGEKGEQMYSGRRRRRSVGV", "length": 1495, "header": "tr|A0A8V0ZC30-1|A0A8V0ZPX4_CHICK Computationally mapped isoform of Collagen alpha-1(XVII) chain OS=Gallus gallus OX=9031 GN=COL17A1 PE=4 SV=1 CANONICAL=A0A8V0ZPX4-1" }, "locus": { "chromosome": "6", "start_pos": 24955487, "end_pos": 24920857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051700.1", "url": "https://www.ensembl.org/id/ENSGALT00010051700.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030837.1", "url": "https://www.ensembl.org/id/ENSGALP00010030837.1" } ] } }, { "isoform_ac": "A0A8V0ZJ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4/entry#A0A8V0ZJ22-1", "sequence": { "sequence": "MDSVTKKTRQDGSEVTERLITETVTTRLTSLPPKGGSSSGLKTSSHTGGSGVEKRSYTHSSGYVTSSGSGRLNSSSSGYRQTQSPSSTLTKSPGSTFERKTYVNRHATYEGSSSANSSPEFPRKEFASASTRGRSQSRESEIRVRLQSASPSGRWTELDDVKRLLKGSRSASCSPTRSSSSTLPIPKKAVVETKMVTESSQSVSGTYDTTILNTTLPPYTWSSTLPAGSSLGGYHNSMGQSSSLINAMSHSTGSVFGVPNNLAPSSHALNTGLSTSSTVFGVQNNLSPSSSALNASAASAAYGMKNTSQTNTMNSTGVSASAGGTILSSQGDDFLHKDCKFLLLEKENAPAKKEMELLVMTKDSGKVFSASSTGLNGGSFAEDTLKKEKQGLSSYAADTGLKSDANGGLKSAPTRDKATYAEIQNGGAGGAIGSAPSWCPCGSCCSWWKWLLGLLLAWLLLLGLLFGLIALAEEVRKLKSRVDNLEKINHSFLTVNQGNPYLEKDVSKVDFLHGVAPSSTFPFENEESVWLMVKSRLNKEIERGYFRGERGEPGMKGDMGLQGPKGDRGLPGVPGIPGPVGHQGPEGPKGQKGSMGDPGMEGPMGQRGREGLPGPRGEPGPPGFGEKGDRGAAGPPGPPGPPGSAGLKGPMGSPGPQGPPGPPGLQGFRGEAGLPGAKGEKGATGPPGPKGDQGEKGARGMTGEQGSRGIPGPPGEPGAKGPAGQAGRDGQPGERGEPGLMGMPGARGPPGPSGDTGEPGLTGPQGPPGLPGNPGRPGAKGEPGAPGKVISAEGSSTIALPGPPGPPGPIGPTGPPGVPGPVGPAGLPGQQGPRGEKGSAGEVVIETIKTEVSSLASQMLSDLQGRAGPPGPPGPPGESVQGLPGPRGPPGLPGPSGPPGRPGSSVSTSETFVSGPPGPPGPPGPKGDQGEPGPRGFTGEPGEPGLPGFSSHGGTVTMQGPPGPPGPPGPKGDAGVPGAPGIPGTSRGGSRQIQGPPGPPGPPGPPGPGGSSSQEIQQYVADYLKSDNVRHYLTGVQGPPGPPGPPGILTTADGKNFDFAELATRVMSYVTREEIRQYLVGPRGPPGPPGPGVDGMSLSLDYDELTRRFISYLTSSGMSIGLPGPPGPPGTPGISYSELTAYLRNSEFSGLVGPPGPAGPPGPPGIPGSSGTSLEDISAYLQSVGYSSISGIQGPPGPPGPPGPPGFSGTGLLSYADITHSDEFRSELIQYLKSDEVRSYISGPPGPPGPRGPPGPKGDSGLVAGSMSSLYHDSLASERLHGGSIGAEGSHGGSLGASSSYGSSMSSSMSSYSASMGSDGSYGASVGSDGSFDGLLTAEESHRRSAGPGRSYSSSFTGSLDYNELARHVSENLQSRGILQDLMSYTGQGPPGPPGPPGPPGISRVFAAYGNVTEDLMDFFRTHGTVRGPPGEKGERGYPGPKGDPGPMGPPGRHGQRGPKGEKGEKGEQMYSGRRRRRSVGV", "length": 1482, "header": "tr|A0A8V0ZJ22-1|A0A8V0ZPX4_CHICK Computationally mapped isoform of Collagen alpha-1(XVII) chain OS=Gallus gallus OX=9031 GN=COL17A1 PE=4 SV=1 CANONICAL=A0A8V0ZPX4-1" }, "locus": { "chromosome": "6", "start_pos": 24955487, "end_pos": 24920857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051628.1", "url": "https://www.ensembl.org/id/ENSGALT00010051628.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030791.1", "url": "https://www.ensembl.org/id/ENSGALP00010030791.1" } ] } }, { "isoform_ac": "A0A8V0ZJ34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4/entry#A0A8V0ZJ34-1", "sequence": { "sequence": "MDSVTKKTRQDGSEVTERLITETVTTRLTSLPPKGGSSSGLKTSSHTGGSGVEKRSYTHSSGYVTSRSSSANSSPEFPRKEFASASTRGRSQSRESEIRVRLQSASPSGRWTELDDVKRLLKGSRSASCSPTRSSSSTLPIPKKAVVETKMVTESSQSVSGTYDTTILNTTLPPYTWSSTLPAGSSLGGYHNSMGQSSSLINAMSHSTGSVFGVPNNLAPSSHALNTGLSTSSTVFGVQNNLSPSSSALNASAASAAYGMKNTSQTNTMNSTGVSASAGGTILSSQGDDFLHKDCKFLLLEKENAPAKKEMELLVMTKDSGKVFSASSTGLNGGSFAEDTLKKEKQGLSSYAADTGLKSDANGGLKSAPTRDKATYAEIQNGGAGGAIGSAPSWCPCGSCCSWWKWLLGLLLAWLLLLGLLFGLIALAEEVRKLKSRVDNLEKINHSFLTVNQGNPYLEKDVSKVDFLHGVAPSSTFPFENEESVWLMVKSRLNKEIERGYFRGERGEPGMKGDMGLQGPKGDRGLPGVPGIPGPVGHQGPEGPKGQKGSMGDPGMEGPMGQRGREGLPGPRGEPGPPGFGEKGDRGAAGPPGPPGPPGSAGLKGPMGSPGPQGPPGPPGLQGFRGEAGLPGAKGEKGATGPPGPKGDQGEKGARGMTGEQGSRGIPGPPGEPGAKGPAGQAGRDGQPGERGEPGLMGMPGARGPPGPSGDTGEPGLTGPQGPPGLPGNPGRPGAKGEPGAPGKVISAEGSSTIALPGPPGPPGPIGPTGPPGVPGPVGPAGLPGQQGPRGEKGSAGEVVIETIKTEVSSLASQMLSDLQGRAGPPGPPGPPGESVQGLPGPRGPPGLPGPSGPPGRPGSSVSTSETFVSGPPGPPGPPGPKGDQGEPGPRGFTGEPGEPGLPGFSSHGGTVTMQGPPGPPGPPGPKGDAGVPGAPGIPGTSRGGSRQIQGPPGPPGPPGPPGPGGSSSQEIQQYVADYLKSDNVRHYLTGVQGPPGPPGPPGILTTADGKNFDFAELATRVMSYVTSSSDHYQSFASSVSTTSVLYQELLNMLQREEIRQYLVGPRGPPGPPGPGVDGMSLSLDYDELTRRFISYLTSSGMSIGLPGPPGPPGTPGISYSELTAYLRNSEFSGLVGPPGPAGPPGPPGIPGSSGTSLEDISAYLQSVGYSSISGIQGPPGPPGPPGPPGFSGTGLLSYADITHSDEFRSELIQYLKSDEVRSYISGPPGPPGPRGPPGPKGDSGLVAGSMSSLYHDSLASERLHGGSIGAEGSHGGSLGASSSYGSSMSSSMSSYSASMGSDGSYGASVGSDGSFDGLLTAEESHRRSAGPGRSYSSSFTGSLDYNELARHVSENLQSRGILQDLMSYTGQGPPGPPGPPGPPGISRVFAAYGNVTEDLMDFFRTHGTVRGPPGEKGERGYPGPKGDPGPMGPPGRHGQRGPKGEKGEKGEQMYSGRRRRRSVGV", "length": 1466, "header": "tr|A0A8V0ZJ34-1|A0A8V0ZPX4_CHICK Computationally mapped isoform of Collagen alpha-1(XVII) chain OS=Gallus gallus OX=9031 GN=COL17A1 PE=4 SV=1 CANONICAL=A0A8V0ZPX4-1" }, "locus": { "chromosome": "6", "start_pos": 24955487, "end_pos": 24920857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051655.1", "url": "https://www.ensembl.org/id/ENSGALT00010051655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030806.1", "url": "https://www.ensembl.org/id/ENSGALP00010030806.1" } ] } }, { "isoform_ac": "A0A8V0ZJ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4/entry#A0A8V0ZJ75-1", "sequence": { "sequence": "MDSVTKKTRQDGSEVTERLITETVTTRLTSLPPKGGSSSGLKTSSHTGGSGVEKRSYTHSSGYVTSSGSGRLNSSSSGYRQTQSPSSTLTKSPGSTFERKTYVNRHATYEGSSSANSSPEFPRKEFASASTRGRSQSRESEIRVRLQSASPSGRWTELDDVKRLLKGSRSASCSPTRSSSSTLPIPKKAVVETKMVTESSQSVSGTYDTTILNTTLPPYTWSSTLPAGSSLGGYHNSMGQSSSLINAMSHSTGSVFGVPNNLAPSSHALNTGLSTSSTVFGVQNNLSPSSSALNASAASAAYGMKNTSQTNTMNSTGVSASAGGTILSSQGDDFLHKDCKFLLLEKENAPAKKEMELLVMTKDSGKVFSASSTGLNGGSFAEDTLKKEKQGLSSYAADTGLKSDANGGLKSAPTRDKATYAEIQNGGAGGAIGSAPSWCPCGSCCSWWKWLLGLLLAWLLLLGLLFGLIALAEEVRKLKSRVDNLEKINHSFLTVNQGNPYLEKDVSKVDFLHGVAPSSTFPFENEESVWLMVKSRLNKEIERGYFRGERGEPGMKGDMGLQGPKGDRGLPGVPGIPGPVGHQGPEGPKGQKGSMGDPGMEGPMGQRGREGLPGPRGEPGPPGFGEKGDRGAAGPPGPPGPPGSAGLKGPMGSPGPQGPPGPPGLQGFRGEAGLPGAKGEKGATGPPGPKGDQGEKGARGMTGEQGSRGIPGPPGEPGAKGPAGQAGRDGQPGERGEPGLMGMPGARGPPGPPGPIGPTGPPGVPGPVGPAGLPGQQGPRGEKGSAGEVVIETIKTEVSSLASQMLSDLQGRAGPPGPPGPPGESVQGLPGPRGPPGLPGPSGPPGRPGSSVSTSETFVSGPPGPPGPPGPKGDQGEPGPRGFTGEPGEPGLPGFSSHGGTVTMQGPPGPPGPPGPKGDAGVPGAPGIPGTSRGGSRQIQGPPGPPGPPGPPGPGGSSSQEIQQYVADYLKSDNVRHYLTGVQGPPGPPGPPGILTTADGKNFDFAELATRVMSYVTSSSDHYQSFASSVSTTSVLYQELLNMLQREEIRQYLVGPRGPPGPPGPGVDGMSLSLDYDELTRRFISYLTSSGMSIGLPGPPGPPGTPGISYSELTAYLRNSEFSGLVGPPGPAGPPGPPGIPGSSGTSLEDISAYLQSVGYSSISGIQGPPGPPGPPGPPGFSGTGLLSYADITHSDEFRSELIQYLKSDEVRSYISGPPGPPGPRGPPGPKGDSGLVAGSMSSLYHDSLASERLHGGSIGAEGSHGGSLGASSSYGSSMSSSMSSYSASMGSDGSYGASVGSDGSFDGLLTAEESHRRSAGPGRSYSSSFTGSLDYNELARHVSENLQSRGILQDLMSYTGQGPPGPPGPPGPPGISRVFAAYGNVTEDLMDFFRTHGTVRGPPGEKGERGYPGPKGDPGPMGPPGRHGQRGPKGEKGEKGEQMYSGRRRRRSVGV", "length": 1456, "header": "tr|A0A8V0ZJ75-1|A0A8V0ZPX4_CHICK Computationally mapped isoform of Collagen alpha-1(XVII) chain OS=Gallus gallus OX=9031 GN=COL17A1 PE=4 SV=1 CANONICAL=A0A8V0ZPX4-1" }, "locus": { "chromosome": "6", "start_pos": 24955487, "end_pos": 24920857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051668.1", "url": "https://www.ensembl.org/id/ENSGALT00010051668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030815.1", "url": "https://www.ensembl.org/id/ENSGALP00010030815.1" } ] } }, { "isoform_ac": "A0A8V0ZJ89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4/entry#A0A8V0ZJ89-1", "sequence": { "sequence": "MDSVTKKTRQDGSEVTERLITETVTTRLTSLPPKGGSSSGLKTSSHTGGSGVEKRSYTHSSGYVTSSGSGRLNSSSSGYRQTQSPSSTLTKSPGSTFERKTYVNRHATYEGSSSANSSPEFPRKEFASASTRGRSQSRESEIRVRLQSASPSGRWTELDDVKRLLKGSRSASCSPTRSSSSTLPIPKKAVVETKMVTESSQSVSGTYDTTILNTTLPPYTWSSTLPAGSSLGGYHNSMGQSSSLINAMSHSTGSVFGVPNNLAPSSHALNTGLSTSSTVFGVQNNLSPSSSALNASAASAAYGMKNTSQTNTMNSTGVSASAGGTILSSQGDDFLHKDCKFLLLEKENAPAKKEMELLVMTKDSGKVFSASSTGLNGGSFAEDTLKKEKQGLSSYAADTGLKSDANGGLKSAPTRDKATYAEIQNGGAGGAIGSAPSWCPCGSCCSWWKWLLGLLLAWLLLLGLLFGLIALAEEVRKLKSRVDNLEKINHSFLTVNQGNPYLEKDVSKVDFLHGVAPSSTFPFENEESVWLMVKSRLNKEIERGYFRGERGEPGMKGDMGLQGPKGDRGLPGVPGIPGPVGHQGPEGPKGQKGSMGDPGMEGPMGQRGREGLPGPRGEPGPPGFGEKGDRGAAGPPGPPGPPGSAGLKGPMGSPGPQGPPGPPGLQGFRGEAGLPGAKGEKGATGPPGPKGDQGEKGARGMTGEQGSRGIPGPPGEPGAKGPAGQAGRDGQPGERGEPGLMGMPGARGPPGPSGDTGEPGLTGPQGPPGLPGNPGRPGAKGEPGAPGKVISAEGSSTIALPGPPGPPGPIGPTGPPGVPGPVGPAGLPGQQGPRGEKGSAGEVVIETIKTEVSSLASQMLSDLQGRAGPPGPPGPKGDAGVPGAPGIPGTSRGGSRQIQGPPGPPGPPGPPGPGGSSSQEIQQYVADYLKSDNVRHYLTGVQGPPGPPGPPGILTTADGKNFDFAELATRVMSYVTSSSDHYQSFASSVSTTSVLYQELLNMLQREEIRQYLVGPRGPPGPPGPGVDGMSLSLDYDELTRRFISYLTSSGMSIGLPGPPGPPGTPGISYSELTAYLRNSEFSGLVGPPGPAGPPGPPGIPGSSGTSLEDISAYLQSVGYSSISGIQGPPGPPGPPGPPGFSGTGLLSYADITHSDEFRSELIQYLKSDEVRSYISGPPGPPGPRGPPGPKGDSGLVAGSMSSLYHDSLASERLHGGSIGAEGSHGGSLGASSSYGSSMSSSMSSYSASMGSDGSYGASVGSDGSFDGLLTAEESHRRSAGPGRSYSSSFTGSLDYNELARHVSENLQSRGILQDLMSYTGQGPPGPPGPPGPPGISRVFAAYGNVTEDLMDFFRTHGTVRGPPGEKGERGYPGPKGDPGPMGPPGRHGQRGPKGEKGEKGEQMYSGRRRRRSVGV", "length": 1415, "header": "tr|A0A8V0ZJ89-1|A0A8V0ZPX4_CHICK Computationally mapped isoform of Collagen alpha-1(XVII) chain OS=Gallus gallus OX=9031 GN=COL17A1 PE=4 SV=1 CANONICAL=A0A8V0ZPX4-1" }, "locus": { "chromosome": "6", "start_pos": 24955487, "end_pos": 24920857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051691.1", "url": "https://www.ensembl.org/id/ENSGALT00010051691.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030830.1", "url": "https://www.ensembl.org/id/ENSGALP00010030830.1" } ] } }, { "isoform_ac": "A0A8V0ZPX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4/entry#A0A8V0ZPX4-1", "sequence": { "sequence": "MDSVTKKTRQDGSEVTERLITETVTTRLTSLPPKGGSSSGLKTSSHTGGSGVEKRSYTHSSGYVTSSGSGRLNSSSSGYRQTQSPSSTLTKSPGSTFERKTYVNRHATYEGSSSANSSPEFPRKEFASASTRGRSQSRESEIRVRLQSASPSGRWTELDDVKRLLKGSRSASCSPTRSSSSTLPIPKKAVVETKMVTESSQSVSGTYDTTILNTTLPPYTWSSTLPAGSSLGGYHNSMGQSSSLINAMSHSTGSVFGVPNNLAPSSHALNTGLSTSSTVFGVQNNLSPSSSALNASAASAAYGMKNTSQTNTMNSTGVSASAGGTILSSQGDDFLHKDCKFLLLEKENAPAKKEMELLVMTKDSGKVFSASSTGLNGGSFAEDTLKKEKQGLSSYAADTGLKSDANGGLKSAPTRDKATYAEIQNGGAGGAIGSAPSWCPCGSCCSWWKWLLGLLLAWLLLLGLLFGLIALAEEVRKLKSRVDNLEKINHSFLTVNQGNPYLEKDVSKVDFLHGVAPSSTFPFENEESVWLMVKSRLNKEIERGYFRGERGEPGMKGDMGLQGPKGDRGLPGVPGIPGPVGHQGPEGPKGQKGSMGDPGMEGPMGQRGREGLPGPRGEPGPPGFGEKGDRGAAGPPGPPGPPGSAGLKGPMGSPGPQGPPGPPGLQGFRGEAGLPGAKGEKGATGPPGPKGDQGEKGARGMTGEQGSRGIPGPPGEPGAKGPAGQAGRDGQPGERGEPGLMGMPGARGPPGPSGDTGEPGLTGPQGPPGLPGNPGRPGAKGEPGAPGKVISAEGSSTIALPGPPGPPGPIGPTGPPGVPGPVGPAGLPGQQGPRGEKGSAGEVVIETIKTEVSSLASQMLSDLQGRAGPPGPPGPPGESVQGLPGPRGPPGLPGPSGPPGRPGSSVSTSETFVSGPPGPPGPPGPKGDQGEPGPRGFTGEPGEPGLPGFSSHGGTVTMQGPPGPPGPPGPKGDAGVPGAPGIPGTSRGGSRQIQGPPGPPGPPGPPGPGGSSSQEIQQYVADYLKSDNVRHYLTGVQGPPGPPGPPGILTTADGKNFDFAELATRVMSYVTSSSDHYQSFASSVSTTSVLYQELLNMLQREEIRQYLVGPRGPPGPPGPGVDGMSLSLDYDELTRRFISYLTSSGMSIGLPGPPGPPGTPGISYSELTAYLRNSEFSGLVGPPGPAGPPGPPGIPGSSGTSLEDISAYLQSVGYSSISGIQGPPGPPGPPGPPGFSGTGLLSYADITHSDEFRSELIQYLKSDEVRSYISGPPGPPGPRGPPGPKGDSGLVAGSMSSLYHDSLASERLHGGSIGAEGSHGGSLGASSSYGSSMSSSMSSYSASMGSDGSYGASVGSDGSFDGLLTAEESHRRSAGPGRSYSSSFTGSLDYNELARHVSENLQSRGILQDLMSYTGQGPPGPPGPPGPPGISRVFAAYGNVTEDLMDFFRTHGTVRGPPGEKGERGYPGPKGDPGPMGPPGRHGQRGPKGEKGEKGEQMYSGRRRRRSVGV", "length": 1510, "header": "tr|A0A8V0ZPX4-1|A0A8V0ZPX4_CHICK Isoform 1 of Collagen alpha-1(XVII) chain OS=Gallus gallus OX=9031 GN=COL17A1 PE=4 SV=1 CANONICAL=A0A8V0ZPX4-1" }, "locus": { "chromosome": "6", "start_pos": 24955487, "end_pos": 24920857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051613.1", "url": "https://www.ensembl.org/id/ENSGALT00010051613.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030783.1", "url": "https://www.ensembl.org/id/ENSGALP00010030783.1" } ] } }, { "isoform_ac": "A0A8V0ZPY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4/entry#A0A8V0ZPY7-1", "sequence": { "sequence": "MDSVTKKTRQDGSEVTERLITETVTTRLTSLPPKGGSSSGLKTSSHTGGSGVEKRSYTHSSGYVTSSGSGRLNSSSSGYRQTQSPSSTLTKSPGSTFERKTYVNRHATYEGSSSANSSPEFPRKEFASASTRGRSQSRESEIRVRLQSASPSGRWTELDDVKRLLKGSRSASCSPTRSSSSTLPIPKKAVVETKMVTESSQSVSGTYDTTILNTTLPPYTWSSTLPAGSSLGGYHNSMGQSSSLINAMSHSTGSVFGVPNNLAPSSHALNTGLSTSSTVFGVQNNLSPSSSALNASAASAAYGMKNTSQTNTMNSTGVSASAGGTILSSQGDDFLHKDCKFLLLEKENAPAKKEMELLVMTKDSGKVFSASSTGLNGGSFAEDTLKKEKQGLSSYAADTGLKSDANGGLKSAPTRDKATYAEIQNGGAGGAIGSAPSWCPCGSCCSWWKWLLGLLLAWLLLLGLLFGLIALAEEVRKLKSRVDNLEKINHSFLTVNQGNPYLEKDVSKVDFLHGVAPSSTFPFENEESVWLMVKSRLNKEIERGYFRGERGEPGMKGDMGLQGPKGDRGLPGVPGIPGPVGHQGPEGPKGQKGSMGDPGMEGPMGQRGREGLPGPRGEPGPPGFGEKGDRGAAGPPGPPGPPGSAGLKGPMGSPGPQGPPGPPGLQGFRGEAGLPGAKGEKGATGPPGPKGDQGEKGARGMTGEQGSRGIPGPPGEPGAKGPAGQAGRDGQPGERGEPGLMGMPGARGPPGPSGDTGEPGLTGPQGPPGLPGNPGRPGAKGEPGAPGKVISAEGSSTIALPGPPGPPGPIGPTGPPGVPGPVGPAGLPGQQGPRGEKGSAGEVVIETIKTEVSSLASQMLSDLQGRAGPPGPPGPPGESVQGLPGPRGPPGLPGPSGPPGRPGSSVSTSETFVSGPPGPPGPPGPKGDQGEPGPRGFTGEPGEPGLPGFSSHGGTVTMQGPPGPPGPPGPKGDAGVPGAPGIPGTSRGDNVRHYLTGVQGPPGPPGPPGILTTADGKNFDFAELATRVMSYVTSSSDHYQSFASSVSTTSVLYQELLNMLQREEIRQYLVGPRGPPGPPGPGVDGMSLSLDYDELTRRFISYLTSSGMSIGLPGPPGPPGTPGISYSELTAYLRNSEFSGLVGPPGPAGPPGPPGIPGSSGTSLEDISAYLQSVGYSSISGIQGPPGPPGPPGPPGFSGTGLLSYADITHSDEFRSELIQYLKSDEVRSYISGPPGPPGPRGPPGPKGDSGLVAGSMSSLYHDSLASERLHGGSIGAEGSHGGSLGASSSYGSSMSSSMSSYSASMGSDGSYGASVGSDGSFDGLLTAEESHRRSAGPGRSYSSSFTGSLDYNELARHVSENLQSRGILQDLMSYTGQGPPGPPGPPGPPGISRVFAAYGNVTEDLMDFFRTHGTVRGPPGEKGERGYPGPKGDPGPMGPPGRHGQRGPKGEKGEKGEQMYSGRRRRRSVGV", "length": 1472, "header": "tr|A0A8V0ZPY7-1|A0A8V0ZPY7_CHICK Computationally mapped isoform of Collagen alpha-1(XVII) chain OS=Gallus gallus OX=9031 GN=COL17A1 PE=4 SV=1 CANONICAL=A0A8V0ZPX4-1" }, "locus": { "chromosome": "6", "start_pos": 24955487, "end_pos": 24920857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051639.1", "url": "https://www.ensembl.org/id/ENSGALT00010051639.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030798.1", "url": "https://www.ensembl.org/id/ENSGALP00010030798.1" } ] } }, { "isoform_ac": "A0A8V0ZQ13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4/entry#A0A8V0ZQ13-1", "sequence": { "sequence": "MDSVTKKTRQDGSEVTERLITETVTTRLTSLPPKGGSSSGLKTSSHTGGSGVEKRSYTHSSGYVTSSGSGRLNSSSSGYRQTQSPSSTLTKSPGSTFERKTYVNRHATYEGSSSANSSPEFPRKEFASASTRGRSQSRESEIRVRLQSASPSGRWTELDDVKRLLKGSRSASCSPTRSSSSTLPIPKKAVVETKMVTESSQSVSGTYDTTILNTTLPPYTWSSTLPAGSSLGGYHNSMGQSSSLINAMSHSTGSVFGVPNNLAPSSHALNTGLSTSSTVFGVQNNLSPSSSALNASAASAAYGMKNTSQTNTMNSTGVSASAGGTILSSQGDDFLHKDCKFLLLEKENAPAKKEMELLVMTKDSGKVFSASSTGLNGGSFAEDTLKKEKQGLSSYAADTGLKSDANGGLKSAPTRDKATYAEIQNGGAGGAIGSAPSWCPCGSCCSWWKWLLGLLLAWLLLLGLLFGLIALAEEVRKLKSRVDNLEKINHSFLTVNQGNPYLEKDVSKVDFLHGVAPSSTFPFENEESVWLMVKSRLNKEIERGYFRGERGEPGMKGDMGLQGPKGDRGLPGVPGIPGPVGHQGPEGPKGQKGSMGDPGMEGPMGQRGREGLPGPRGEPGPPGFGEKGDRGAAGPPGPPGPPGSAGLKGPMGSPGPQGPPGPPGLQGFRGEAGLPGAKGEKGATGPPGPKGDQGEKGARGMTGEQGSRGIPGPPGEPGAKGPAGQAGRDGQPGERGEPGLMGMPGARGPPGPSGDTGEPGLTGPQGPPGLPGNPGRPGAKGEPGAPGKVISAEGSSTIALPGPPGPPGPIGPTGPPGVPGPVGPAGLPGQQGPRGEKGSAGEVVIETIKTEVSSLASQMLSDLQGRAGPPGPPGPPGESVQGLPGPRGPPGLPGPSGPPGRPGSSVSTSETFVSGPPGPPGPPGPKGDQGEPGPRGFTGEPGEPGLPGFSSHGGTVTMQGPPGPPGPPGILTTADGKNFDFAELATRVMSYVTSSSDHYQSFASSVSTTSVLYQELLNMLQREEIRQYLVGPRGPPGPPGPGVDGMSLSLDYDELTRRFISYLTSSGMSIGLPGPPGPPGTPGISYSELTAYLRNSEFSGLVGPPGPAGPPGPPGIPGSSGTSLEDISAYLQSVGYSSISGIQGPPGPPGPPGPPGFSGTGLLSYADITHSDEFRSELIQYLKSDEVRSYISGPPGPPGPRGPPGPKGDSGLVAGSMSSLYHDSLASERLHGGSIGAEGSHGGSLGASSSYGSSMSSSMSSYSASMGSDGSYGASVGSDGSFDGLLTAEESHRRSAGPGRSYSSSFTGSLDYNELARHVSENLQSRGILQDLMSYTGQGPPGPPGPPGPPGISRVFAAYGNVTEDLMDFFRTHGTVRGPPGEKGERGYPGPKGDPGPMGPPGRHGQRGPKGEKGEKGEQMYSGRRRRRSVGV", "length": 1432, "header": "tr|A0A8V0ZQ13-1|A0A8V0ZQ13_CHICK Computationally mapped isoform of Collagen alpha-1(XVII) chain OS=Gallus gallus OX=9031 GN=COL17A1 PE=4 SV=1 CANONICAL=A0A8V0ZPX4-1" }, "locus": { "chromosome": "6", "start_pos": 24955487, "end_pos": 24920857, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051680.1", "url": "https://www.ensembl.org/id/ENSGALT00010051680.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030823.1", "url": "https://www.ensembl.org/id/ENSGALP00010030823.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1159, "start_aa": "Thr", "end_pos": 1159, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1159", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 813, "start_aa": "Thr", "end_pos": 813, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr813", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:396503", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396503", "resource": "KEGG Pathway" }, { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-446107", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-446107", "resource": "Reactome", "description": "Type I hemidesmosome assembly" }, { "id": "R-GGA-8948216", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "resource": "Reactome", "description": "Collagen chain trimerization" } ], "orthologs": [ { "uniprot_canonical_ac": "Q07563-1", "protein_name": "Collagen alpha-1(XVII) chain", "gene_name": "Col17a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDVTKKSKRDGTEVTERIVTETVTTRLTSLPPKGSTSNGYAKTGSLGGGSRLEKQSLTHGSSGYINSSGSIRGNASTSSYRRTHSPASTLPNSPGSTFERKAHMTRHGTYEGSSSGNSSPEYPRKELASSSTRGRSQTRESEIRVRLQSASPSTRWTELDEVKRLLKGSRSASASPTRNTSNTLPIPKKGTVETKTVTASSHSVSGTYDSAILDTNFPPHMWSSTLPAGSSLGTYQNNITAQSTSLLNTNAYSTGSVFGVPNNMASCSPTLHPGLSSCSSVFGMQNNLAPSSSVLSHGTTTASTAYGAKKNVPQPPTVTSTGVSTSATCTTSVQSDDLLHKDCKFLILEKDNTPAKKEMELLIMTKDSGKVFTASPATISSTSFSEDTLKKEKQAAYAADTCLKADVNGDLNTVSTKSKMTSAENHGYDRGGGGGRGKGGGAGGGGGGGGASGGGGAWGAAPAWCPCGSCCSWWKWLLGLLLTWLLLLGLLFGLIALAEEVRKLKARVEELEKTKVLYHDVQMDKSNRDRLQAEAPSLGPGLGKAELDGYSQEAIWLFVRNKLMTEQENGNLRGSPGPKGDMGSQGPKGDRGLPGTPGIPGPLGHPGPEGPKGQKGSIGDPGMEGPIGQRGLAGPMGPRGEPGPPGSGEKGDRGIAGEQGPQGLPGVPGPPGLRGHSGSPGPQGPPGAVGPQGLRGDVGLPGVKGDKGLMGPPGPKGDQGEKGPRGLTGEPGIRGLPGAVGEPGAKGAMGPAGADGQQGSRGEQGLTGMPGTRGPPGPAGDPGKPGLTGPQGPQGLPGSPGRPGTKGEPGAPGRVMTSEGSSTITVPGPPGPPGAMGPPGPPGTPGPAGPAGLPGQQGPRGEPGLAGDSFLSSGSSISEVLSAQGVDLRGPPGPPGPRGPPGPSIPGPPGPRGPPGEGVPGPPGPPGSFLTDSETFFTGPPGPPGPPGPKGDQGDPGVPGTPGISGGLSHGASSSTLYMQGPPGPPGPPGPPGSLSSSGQDIQHYIAEYMQSDNIRTYLSGVQGPPGPPGPPGPVITITGETFDYSQLASQVVSYLRSSGYGAGLSSASSSEDILAMLRRNDVWQYLRQNLVGPPGPPGPPGVSGDGSLLSLDYGELSRHILNYMSSSGISFGHPGPPGPPGLPGTSYEELLTMLRGSDYRNIIGPPGPPGPPGMPGNAWSSISVEDLSSYLHTAGLSSIPGPPGPPGPPGPRGPPGVSAALSTYAAENSDNFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDGHLRENYNWSSNSSARRGTSYSSSTGTGGTNGGSLGEGGAYGAGDGGPYGTDIGPGGGYGAAAGGGIYGTNGDSFRDGFTGDLDYNKLAVRVSESMQRQGLLQGMAYTVQGPPGPQGPPGISRVFSAYSNVTQDLMDFFQTYGTIPGPPGQKGDVGTPGPKGDRGPAGPRGPPGPPGPRGNKGEKGDKGDQVYTGRRKRSIAIKP", "length": 1470 }, "evidence": [ { "id": "A0A8V0ZPX4", "url": "https://omabrowser.org/oma/group/A0A8V0ZPX4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UMD9-1", "protein_name": "Collagen alpha-1(XVII) chain", "gene_name": "COL17A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVTKKNKRDGTEVTERIVTETVTTRLTSLPPKGGTSNGYAKTASLGGGSRLEKQSLTHGSSGYINSTGSTRGHASTSSYRRAHSPASTLPNSPGSTFERKTHVTRHAYEGSSSGNSSPEYPRKEFASSSTRGRSQTRESEIRVRLQSASPSTRWTELDDVKRLLKGSRSASVSPTRNSSNTLPIPKKGTVETKIVTASSQSVSGTYDATILDANLPSHVWSSTLPAGSSMGTYHNNMTTQSSSLLNTNAYSAGSVFGVPNNMASCSPTLHPGLSTSSSVFGMQNNLAPSLTTLSHGTTTTSTAYGVKKNMPQSPAAVNTGVSTSAACTTSVQSDDLLHKDCKFLILEKDNTPAKKEMELLIMTKDSGKVFTASPASIAATSFSEDTLKKEKQAAYNADSGLKAEANGDLKTVSTKGKTTTADIHSYGSSGGGGSGGGGGVGGAGGGPWGPAPAWCPCGSCCSWWKWLLGLLLTWLLLLGLLFGLIALAEEVRKLKARVDELERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP", "length": 1497 }, "evidence": [ { "id": "A0A8V0ZPX4", "url": "https://omabrowser.org/oma/group/A0A8V0ZPX4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4" } ], "pmid": "" }, { "name": "hemidesmosome", "id": "GO:0030056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030056", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4" } ], "pmid": "" }, { "name": "hemidesmosome assembly", "id": "GO:0031581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031581", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1439, "end_pos": 1441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": 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"A0A8V0ZQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0" } ] } ], "protein_names": [ { "name": "PPFIA binding protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZCU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCU6#function" }, { "database": "UniProtKB", "id": "ARBA00060046", "url": "https://www.uniprot.org/uniprotkb/ARBA00060046#function" }, { "database": "UniProtKB", "id": "A0A8V0ZIC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZIE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE7#function" }, { "database": "UniProtKB", "id": "A0A8V0ZIF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF6#function" }, { "database": "UniProtKB", "id": "A0A8V0ZQS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZQS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PPFIBP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0", "locus": { "chromosome": "5", "start_pos": 7077450, "end_pos": 6984514, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021474", "url": "https://www.ensembl.org/id/ENSGALG00010021474" } ] } } ], "crossref": [ { "id": "A0A8V0ZQS0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09563", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09563", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09566", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09566", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428843", "url": "https://www.ncbi.nlm.nih.gov/gene/428843", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCU6", "url": "https://www.orthodb.org/?gene=A0A8V0ZCU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIC5", "url": "https://www.orthodb.org/?gene=A0A8V0ZIC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIE7", "url": "https://www.orthodb.org/?gene=A0A8V0ZIE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIF6", "url": "https://www.orthodb.org/?gene=A0A8V0ZIF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQS0", "url": "https://www.orthodb.org/?gene=A0A8V0ZQS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQS5", "url": "https://www.orthodb.org/?gene=A0A8V0ZQS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-388844", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZCU6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIE7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQS5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASDASHMLEAALEQMDDIIAGTKSAAEYANGAYDIVSPAPSVYLGTFQILHLLEDLKMALEMLEDPQEKEALRNQIPGATAVCIREWFEENLSQVNHHSSTNNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEICLEGHQLKLNATEEMLQQELLSRTSLETQKLDLMAEVSDLKIKLVGMEKEQSEYEEKQNKAESVVNLISELQEQMCRLQLEINSRIQERKSQDRKSSVTPNGPQSSPRSVVETLGQKNCSQCDGLLQELRHLKIKVEELENERNQYEWKLKATKAEIAQLQEQLALKDAEIERLQCQLSRTSSHSEVAEREEVYKRRLKEKHQEVQRLKIGMESLLAANEEKDRRIEELTLLLSQYRRVKEIMIAAQGSSDRIVSGGSEEELEATLRKLNVLSNPQGELFKAEASSGELSPALLSPVTHKTTEIRVPQKKKSSSLEDLQSESLEKSKPLVKGSKYQTLPGKLPRPTQNGDQGTYNETNSPHMNDTEDSSILGLNRIRSVSAPVLGETENTDGTVVSDDLSPLSSGTDSGPQSPLSLENRKSPKGIKKIWGKIRRTQSGNFPADDLGLAEFRRGGLRATAGPRLSRSKETKGQKNDYNAPFAQWSTERVCNWLEDFGLGQYVIFARQWVTSGHTLLTATPQDMEKEMGIKHPLHRKKLVLAIKSISTKQDEKSAQLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHINNFNPHCLRRRPVEESNVPPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFNGDTLAMLLNIPPQKTLLRRHLTTNFNVLIGPETQQEKRDITESTAYTPLTTTAKVRPKKLGFSHFGNLRKKKFDESTDYVCPMDTNPGATNGTQKNYTGYKGLSPLTDRELDQMEHSEGTVKQIGAFSQGISNLTTMLSQDEMLNDSRFLTPTLEDWR", "length": 983, "header": "tr|A0A8V0ZQS0-1|A0A8V0ZQS0_CHICK Isoform 1 of PPFIA binding protein 2 OS=Gallus gallus OX=9031 GN=PPFIBP2 PE=1 SV=1 CANONICAL=A0A8V0ZQS0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZCU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0/entry#A0A8V0ZCU6-1", "sequence": { "sequence": "MASDASHMLEAALEQMDDIIAGTKSAAEYANGAYDIVSPAPSVYLGTFQILHLLEDLKMALEMLEDPQEKEALRNQIPGATAVCIREWFEENLSQVNHHSSTNNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEICLEGHQLKLNATEEMLQQELLSRTSLETQKLDLMAEVSDLKIKLVGMEKEQSEYEEKQNKAEGLLQELRHLKIKVEELENERNQYEWKLKATKAEIAQLQEQLALKDAEIERLQCQLSRTSSHSEVAERDQEVQRLKIGMESLLAANEEKDRRIEELTLLLSQYRRVKEIMIAAQGSSDRIVSGGSEEELEATLRKLNVLSNPQGELFKAEASSGELSPALLSPVTHKTTEIRVPQKKKSSSLEDLQSESLEKYVDGKPVQPVVEQESKPLVKGSKYQTLPGKLPRPTQNGDQGTYNETNSPHMNDTEDSSILGLRETENTDGTVVSDDLSPLSSGTDSGPQSPLSLENRKSPKGIKKIWGKIRRTQSGNFPADDLGLAEFRRGGLRATAGPRLSRSKETKGQKNDYNAPFAQWSTERVCNWLEDFGLGQYVIFARQWVTSGHTLLTATPQDMEKEMGIKHPLHRKKLVLAIKSISTKQDEKSAQLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHINNFNPHCLRRRPVEESNVPPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFNGDTLAMLLNIPPQKTLLRRHLTTNFNVLIGPETQQEKRDITESTAYTPLTTTAKVRPKKLGFSHFGNLRKKKFDESTDYVCPMDTNPGATNGTQKNYTGYKGLSPLTDRELDQVGQTD", "length": 874, "header": "tr|A0A8V0ZCU6-1|A0A8V0ZQS0_CHICK Computationally mapped isoform of PPFIA binding protein 2 OS=Gallus gallus OX=9031 GN=PPFIBP2 PE=1 SV=1 CANONICAL=A0A8V0ZQS0-1" }, "locus": { "chromosome": "5", "start_pos": 7074872, "end_pos": 7005515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052081.1", "url": "https://www.ensembl.org/id/ENSGALT00010052081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031093.1", "url": "https://www.ensembl.org/id/ENSGALP00010031093.1" } ] } }, { "isoform_ac": "A0A8V0ZIC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0/entry#A0A8V0ZIC5-1", "sequence": { "sequence": "MASDASHMLEAALEQMDDIIAGTKSAAEYANGAYDIVSPAPSVYLGTFQILHLLEDLKMALEMLEDPQEKEALRNQIPGATAVCIREWFEENLSQVNHHSSTNNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEICLEGHQLKLNATEEMLQQELLSRTSLETQKLDLMAEVSDLKIKLVGMEKEQSEYEEKQNKAEGLLQELRHLKIKVEELENERNQYEWKLKATKAEIAQLQEQLALKDAEIERLQCQLSRTSSHSEVAERDQEVQRLKIGMESLLAANEEKDRRIEELTLLLSQYRRVKEIMIAAQGSSDRIVSGGSEEELEATLRKLNVLSNPQGELFKAEASSGELSPALLSPVTHKTTEIRVPQKKKSSSLEDLQSESLEKYVDGKPVQPVVEQESKPLVKGSKYQTLPGKLPRPTQNGDQGTYNETNSPHMNDTEDSSILGLRETENTDGTVVSDDLSPLSSGTDSGPQSPLSLENRKSPKGIKKIWGKIRRTQSGNFPADDLGLAEFRRGGLRATAGPRLSRSKETKGQKNDYNAPFAQWSTERVCNWLEDFGLGQYVIFARQWVTSGHTLLTATPQDMEKEMGIKHPLHRKKLVLAIKSISTKQDEKSAQLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHINNFNPHCLRRRPVEEVKSNVPPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFNGDTLAMLLNIPPQKTLLRRHLTTNFNVLIGPETQQEKRDITESTAYTPLTTTAKVRPKKLGFSHFGNLRKKKFDESTDYVCPMDTNPGATNGTQKNYTGYKGLSPLTDRELDQVGQTD", "length": 876, "header": "tr|A0A8V0ZIC5-1|A0A8V0ZQS0_CHICK Computationally mapped isoform of PPFIA binding protein 2 OS=Gallus gallus OX=9031 GN=PPFIBP2 PE=1 SV=1 CANONICAL=A0A8V0ZQS0-1" }, "locus": { "chromosome": "5", "start_pos": 7074872, "end_pos": 7005515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052059.1", "url": "https://www.ensembl.org/id/ENSGALT00010052059.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031075.1", "url": "https://www.ensembl.org/id/ENSGALP00010031075.1" } ] } }, { "isoform_ac": "A0A8V0ZIE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0/entry#A0A8V0ZIE7-1", "sequence": { "sequence": "MASDASHMLEAALEQMDDIIAGTKSAAEYANGAYDIVSPAPSVYLGTFQILHLLEDLKMALEMLEDPQEKEALRNQIPGATAVCIREWFEENLSQVNHHSSTNNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEICLEGHQLKLNATEEMLQQELLSRTSLETQKLDLMAEVSDLKIKLVGMEKEQSEYEEKQNKAESVVNLISELQEQMCRLQLEINSRIQERKSQDRKSSVTPNGPQSSPRSVVETLGQKNCSQCDGLLQELRHLKIKVEELENERNQYEWKLKATKAEIAQLQEQLALKDAEIERLQCQLSRTSSHSEVAERDQEVQRLKIGMESLLAANEEKDRRIEELTLLLSQYRRVKEIMIAAQGSSDRIVSGGSEEELEATLRKLNVLSNPQGELFKAEASSGELSPALLSPVTHKTTEIRVPQKKKSSSLEDLQSESLEKSKPLVKGSKYQTLPGKLPRPTQNGDQGTYNETNSPHMNDTEDSSILGLNRIRSVSAPVLGETENTDGTVVSDDLSPLSSGTDSGPQSPLSLENRKSPKGIKKIWGKIRRTQSGNFPADDLGLAEFRRGGLRATAGPRLSRSKETKGQKNDYNAPFAQWSTERVCNWLEDFGLGQYVIFARQWVTSGHTLLTATPQDMEKEMGIKHPLHRKKLVLAIKSISTKQDEKSAQLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHINNFNPHCLRRRPVEESNVPPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFNGDTLAMLLNIPPQKTLLRRHLTTNFNVLIGPETQQEKRDITESTAYTPLTTTAKVRPKKLGFSHFGNLRKKKFDESTDYVCPMDTNPGATNGTQKNYTGYKGLSPLTDRELDQVGQTD", "length": 932, "header": "tr|A0A8V0ZIE7-1|A0A8V0ZQS0_CHICK Computationally mapped isoform of PPFIA binding protein 2 OS=Gallus gallus OX=9031 GN=PPFIBP2 PE=1 SV=1 CANONICAL=A0A8V0ZQS0-1" }, "locus": { "chromosome": "5", "start_pos": 7074872, "end_pos": 7005515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052088.1", "url": "https://www.ensembl.org/id/ENSGALT00010052088.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031100.1", "url": "https://www.ensembl.org/id/ENSGALP00010031100.1" } ] } }, { "isoform_ac": "A0A8V0ZIF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0/entry#A0A8V0ZIF6-1", "sequence": { "sequence": "MASDASHMLEAALEQMDDIIAGTKSAAEYANGAYDIVSPAPSVYLGTFQILHLLEDLKMALEMLEDPQEKEALRNQIPGATAVCIREWFEENLSQVNHHSSTNNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEICLEGHQLKLNATEEMLQQELLSRTSLETQKLDLMAEVSDLKIKLVGMEKEQSEYEEKQNKAEGLLQELRHLKIKVEELENERNQYEWKLKATKAEIAQLQEQLALKDAEIERLQCQLSRTSSHSEVAEREEVYKRRLKEKHQEVQRLKIGMESLLAANEEKDRRIEELTLLLSQYRRVKEIMIAAQGSSDRIVSGGSEEELEATLRKLNVLSNPQGELFKAEASSGELSPALLSPVTHKTTEIRVPQKKKSSSLEDLQSESLEKYVDGKPVQPVVEQESKPLVKGSKYQTLPGKLPRPTQNGDQGTYNETNSPHMNDTEDSSILGLRETENTDGTVVSDDLSPLSSGTDSGPQSPLSLENRKSPKGIKKIWGKIRRTQSGNFPADDLGLAEFRRGGLRATAGPRLSRSKETKGQKNDYNAPFAQWSTERVCNWLEDFGLGQYVIFARQWVTSGHTLLTATPQDMEKEMGIKHPLHRKKLVLAIKSISTKQDEKSAQLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHINNFNPHCLRRRPVEESNVPPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFNGDTLAMLLNIPPQKTLLRRHLTTNFNVLIGPETQQEKRDITESTAYTPLTTTAKVRPKKLGFSHFGNLRKKKFDESTDYVCPMDTNPGATNGTQKNYTGYKGLSPLTDRELDQVGQTD", "length": 885, "header": "tr|A0A8V0ZIF6-1|A0A8V0ZQS0_CHICK Computationally mapped isoform of PPFIA binding protein 2 OS=Gallus gallus OX=9031 GN=PPFIBP2 PE=1 SV=1 CANONICAL=A0A8V0ZQS0-1" }, "locus": { "chromosome": "5", "start_pos": 7074872, "end_pos": 7005515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052101.1", "url": "https://www.ensembl.org/id/ENSGALT00010052101.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031110.1", "url": "https://www.ensembl.org/id/ENSGALP00010031110.1" } ] } }, { "isoform_ac": "A0A8V0ZQS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0/entry#A0A8V0ZQS0-1", "sequence": { "sequence": "MASDASHMLEAALEQMDDIIAGTKSAAEYANGAYDIVSPAPSVYLGTFQILHLLEDLKMALEMLEDPQEKEALRNQIPGATAVCIREWFEENLSQVNHHSSTNNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEICLEGHQLKLNATEEMLQQELLSRTSLETQKLDLMAEVSDLKIKLVGMEKEQSEYEEKQNKAESVVNLISELQEQMCRLQLEINSRIQERKSQDRKSSVTPNGPQSSPRSVVETLGQKNCSQCDGLLQELRHLKIKVEELENERNQYEWKLKATKAEIAQLQEQLALKDAEIERLQCQLSRTSSHSEVAEREEVYKRRLKEKHQEVQRLKIGMESLLAANEEKDRRIEELTLLLSQYRRVKEIMIAAQGSSDRIVSGGSEEELEATLRKLNVLSNPQGELFKAEASSGELSPALLSPVTHKTTEIRVPQKKKSSSLEDLQSESLEKSKPLVKGSKYQTLPGKLPRPTQNGDQGTYNETNSPHMNDTEDSSILGLNRIRSVSAPVLGETENTDGTVVSDDLSPLSSGTDSGPQSPLSLENRKSPKGIKKIWGKIRRTQSGNFPADDLGLAEFRRGGLRATAGPRLSRSKETKGQKNDYNAPFAQWSTERVCNWLEDFGLGQYVIFARQWVTSGHTLLTATPQDMEKEMGIKHPLHRKKLVLAIKSISTKQDEKSAQLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHINNFNPHCLRRRPVEESNVPPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFNGDTLAMLLNIPPQKTLLRRHLTTNFNVLIGPETQQEKRDITESTAYTPLTTTAKVRPKKLGFSHFGNLRKKKFDESTDYVCPMDTNPGATNGTQKNYTGYKGLSPLTDRELDQMEHSEGTVKQIGAFSQGISNLTTMLSQDEMLNDSRFLTPTLEDWR", "length": 983, "header": "tr|A0A8V0ZQS0-1|A0A8V0ZQS0_CHICK Isoform 1 of PPFIA binding protein 2 OS=Gallus gallus OX=9031 GN=PPFIBP2 PE=1 SV=1 CANONICAL=A0A8V0ZQS0-1" }, "locus": { "chromosome": "5", "start_pos": 7077126, "end_pos": 7005515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052066.1", "url": "https://www.ensembl.org/id/ENSGALT00010052066.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031079.1", "url": "https://www.ensembl.org/id/ENSGALP00010031079.1" } ] } }, { "isoform_ac": "A0A8V0ZQS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0/entry#A0A8V0ZQS5-1", "sequence": { "sequence": "MASDASHMLEAALEQMDDIIAGTKSAAEYANGAYDIVSPAPSVYLGTFQILHLLEDLKMALEMLEDPQEKEALRNQIPGATAVCIREWFEENLSQVNHHSSTNNETYQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEICLEGHQLKLNATEEMLQQELLSRTSLETQKLDLMAEVSDLKIKLVGMEKEQSEYEEKQNKAESVVNLISELQEQMCRLQLEINSRIQERKSQDRKSSVTPNGPQSSPRSVVETLGQKNCSQCDGLLQELRHLKIKVEELENERNQYEWKLKATKAEIAQLQEQLALKDAEIERLQCQLSRTSSHSEVAERDQEVQRLKIGMESLLAANEEKDRRIEELTLLLSQYRRVKEIMIAAQGSSDRIVSGGSEEELEATLRKLNVLSNPQGELFKAEASSGELSPALLSPVTHKTTEIRVPQKKKSSSLEDLQSESLEKSKPLVKGSKYQTLPGKLPRPTQNGDQGTYNETNSPHMNDTEDSSILGLNRIRSVSAPVLGETENTDGTVVSDDLSPLSSGTDSGPQSPLSLENRKSPKGIKKIWGKIRRTQSGNFPADDLGLAEFRRGGLRATAGPRLSRSKETKGQKNDYNAPFAQWSTERVCNWLEDFGLGQYVIFARQWVTSGHTLLTATPQDMEKEMGIKHPLHRKKLVLAIKSISTKQDEKSAQLDHIWVTRWLDDIGLPQYKDQFHESRVDGRMLQYLTVNDLLFLKVTSQLHHLSIKCAIHVLHINNFNPHCLRRRPVEEVKSNVPPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEPRFNGDTLAMLLNIPPQKTLLRRHLTTNFNVLIGPETQQEKRDITESTAYTPLTTTAKVRPKKLGFSHFGNLRKKKFDESTDYVCPMDTNPGATNGTQKNYTGYKGLSPLTDRELDQMEHSEGTVKQIGAFSQGISNLTTMLSQDEMLNDSRFLTPTLEDWR", "length": 974, "header": "tr|A0A8V0ZQS5-1|A0A8V0ZQS5_CHICK Computationally mapped isoform of PPFIA binding protein 2 OS=Gallus gallus OX=9031 GN=PPFIBP2 PE=1 SV=1 CANONICAL=A0A8V0ZQS0-1" }, "locus": { "chromosome": "5", "start_pos": 7077126, "end_pos": 7005515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052072.1", "url": "https://www.ensembl.org/id/ENSGALT00010052072.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031084.1", "url": "https://www.ensembl.org/id/ENSGALP00010031084.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-388844", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-388844", "resource": "Reactome", "description": "Receptor-type tyrosine-protein phosphatases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuromuscular junction development", "id": "GO:0007528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007528", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" }, { "start_pos": 921, "end_pos": 923, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" }, { "start_pos": 958, "end_pos": 960, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS0" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 627, "end_pos": 691, "start_aa": "Trp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 154, "end_pos": 156 }, { "start_pos": 262, "end_pos": 264 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 507, "end_pos": 509 }, { "start_pos": 916, "end_pos": 918 }, { "start_pos": 921, "end_pos": 923 }, { "start_pos": 92, "end_pos": 94 }, { "start_pos": 958, "end_pos": 960 }, { "start_pos": 970, "end_pos": 972 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZR83-1", "uniprot_ac": "A0A8V0ZR83", "uniprot_id": "A0A8V0ZR83_CHICK", "mass": { "chemical_mass": 27946.0, "monoisotopic_mass": 27946.0 }, "refseq": {}, "gene_names": [ { "name": "CBX1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ] } ], "protein_names": [ { "name": "Chromobox 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CBX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83", "locus": { "chromosome": "27", "start_pos": 3677445, "end_pos": 3668689, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021565", "url": "https://www.ensembl.org/id/ENSGALG00010021565" } ] } } ], "crossref": [ { "id": "A0A8V0ZR83", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR83", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18650", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18650", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18654", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18654", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000953", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000953", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDA3", "url": "https://www.orthodb.org/?gene=A0A8V0ZDA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIS9", "url": "https://www.orthodb.org/?gene=A0A8V0ZIS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKE4", "url": "https://www.orthodb.org/?gene=A0A8V0ZKE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR83", "url": "https://www.orthodb.org/?gene=A0A8V0ZR83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22812", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22812", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9940465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940465", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZDA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AASLRNRWRGCASLCLAPLAEKKLFLVPNSNSKPSPLILKPKILCSVARKLKNWPAQWEKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHESEKSEGSKRKAESDTEDKGEESKPKKKKEESEKPRGFARGFEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANIKCPQVVISFYEERLTWHSYPSEDDDKKEDKN", "length": 242, "header": "tr|A0A8V0ZR83-1|A0A8V0ZR83_CHICK Isoform 1 of Chromobox 1 OS=Gallus gallus OX=9031 GN=CBX1 PE=1 SV=1 CANONICAL=A0A8V0ZR83-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83/entry#A0A8V0ZDA3-1", "sequence": { "sequence": "MGSLCLAPLAEKKLFLVPNSNSKPSPLILKPKILCSVARKLKNWPAQWEKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHESEKSEGSKRKAESDTEDKGEESKPKKKKEESEKPRGFARGFEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANIKCPQVVISFYEERLTWHSYPSEDDDKKEDKN", "length": 232, "header": "tr|A0A8V0ZDA3-1|A0A8V0ZR83_CHICK Computationally mapped isoform of Chromobox 1 OS=Gallus gallus OX=9031 GN=CBX1 PE=1 SV=1 CANONICAL=A0A8V0ZR83-1" }, "locus": { "chromosome": "27", "start_pos": 3675940, "end_pos": 3669460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052325.1", "url": "https://www.ensembl.org/id/ENSGALT00010052325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031263.1", "url": "https://www.ensembl.org/id/ENSGALP00010031263.1" } ] } }, { "isoform_ac": "A0A8V0ZIS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83/entry#A0A8V0ZIS9-1", "sequence": { "sequence": "MLHLCNTAEPALPLSSSPACSDADPSLSETTSSVARKLKNWPAQWEKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHESEKSEGSKRKAESDTEDKGEESKPKKKKEESEKPRGFARGFEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANIKCPQVVISFYEERLTWHSYPSEDDDKKEDKN", "length": 229, "header": "tr|A0A8V0ZIS9-1|A0A8V0ZR83_CHICK Computationally mapped isoform of Chromobox 1 OS=Gallus gallus OX=9031 GN=CBX1 PE=1 SV=1 CANONICAL=A0A8V0ZR83-1" }, "locus": { "chromosome": "27", "start_pos": 3675940, "end_pos": 3671966, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052322.1", "url": "https://www.ensembl.org/id/ENSGALT00010052322.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031260.1", "url": "https://www.ensembl.org/id/ENSGALP00010031260.1" } ] } }, { "isoform_ac": "A0A8V0ZKE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83/entry#A0A8V0ZKE4-1", "sequence": { "sequence": "SWAVKERGEELWARRGFAPPEEEEDPGGGGAVLPPLRSGRPRSVARKLKNWPAQWEKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHESEKSEGSKRKAESDTEDKGEESKPKKKKEESEKPRGFARGFEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANIKCPQVVISFYEERLTWHSYPSEDDDKKEDKN", "length": 239, "header": "tr|A0A8V0ZKE4-1|A0A8V0ZR83_CHICK Computationally mapped isoform of Chromobox 1 OS=Gallus gallus OX=9031 GN=CBX1 PE=1 SV=1 CANONICAL=A0A8V0ZR83-1" }, "locus": { "chromosome": "27", "start_pos": 3675940, "end_pos": 3668984, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052329.1", "url": "https://www.ensembl.org/id/ENSGALT00010052329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031267.1", "url": "https://www.ensembl.org/id/ENSGALP00010031267.1" } ] } }, { "isoform_ac": "A0A8V0ZR83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83/entry#A0A8V0ZR83-1", "sequence": { "sequence": "AASLRNRWRGCASLCLAPLAEKKLFLVPNSNSKPSPLILKPKILCSVARKLKNWPAQWEKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHESEKSEGSKRKAESDTEDKGEESKPKKKKEESEKPRGFARGFEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANIKCPQVVISFYEERLTWHSYPSEDDDKKEDKN", "length": 242, "header": "tr|A0A8V0ZR83-1|A0A8V0ZR83_CHICK Isoform 1 of Chromobox 1 OS=Gallus gallus OX=9031 GN=CBX1 PE=1 SV=1 CANONICAL=A0A8V0ZR83-1" }, "locus": { "chromosome": "27", "start_pos": 3675940, "end_pos": 3668745, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052333.1", "url": "https://www.ensembl.org/id/ENSGALT00010052333.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031269.1", "url": "https://www.ensembl.org/id/ENSGALP00010031269.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9940465", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9940465", "resource": "Reactome", "description": "ChAHP complex assembly" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 11, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "female pronucleus", "id": "GO:0001939", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001939", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "male pronucleus", "id": "GO:0001940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001940", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "chromocenter", "id": "GO:0010369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010369", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "histone methyltransferase binding", "id": "GO:1990226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "histone H3K9me2/3 reader activity", "id": "GO:0062072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" } ], "pmid": "" }, { "name": "histone H1K26me1 reader activity", "id": "GO:0160267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160267", 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"ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZR83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR83" }, { "id": "PS50013", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromo", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 136, "start_aa": "Tyr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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"A0A8V0ZR99-1", "uniprot_ac": "A0A8V0ZR99", "uniprot_id": "A0A8V0ZR99_CHICK", "mass": { "chemical_mass": 40942.0, "monoisotopic_mass": 40942.0 }, "refseq": { "ac": "XP_040507250", "name": "probable pleckstrin homology domain-containing family N member 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507250" }, "gene_names": [ { "name": "ARHGEF7L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99" } ] }, { "name": "ARHGEF7L", "type": "synonym", "evidence": [ { "id": "XP_040507250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507250" } ] } ], "protein_names": [ { "name": "PH domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99/entry#names_and_taxonomy" } ] }, { "name": "probable pleckstrin homology domain-containing family N member 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040507250", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507250" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040507250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507250" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGEF7L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZR99", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR99", "database": "AlphaFoldDB", "categories": [] }, { "id": "419425", "url": "https://www.ncbi.nlm.nih.gov/gene/419425", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MVHIINT", "url": "https://omabrowser.org/oma/group/MVHIINT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDE4", "url": "https://www.orthodb.org/?gene=A0A8V0ZDE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIW1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIW8", "url": "https://www.orthodb.org/?gene=A0A8V0ZIW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR99", "url": "https://www.orthodb.org/?gene=A0A8V0ZR99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46026:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46026:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_040507250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040507250", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCCSLSARHAGSAGGSQDEVELLKTGRTRKWSISDAQSEGSLQPKDPAIPTETEGAEALWGRTQEELLNLLIAQPIAGWEGRNILSLGEIIWSSWVFLRSYHMEEMSERYLVLTSFHLLILSVDHTKKAFVYEGLVPLAGMHLREVLTAISCTFEITGPMIESRLICCQNSADFERWIQHLQDQIKMANANYSTSPTSNISFLVPCDEQWKKRELMRHLLCNTILKWEGKPIQHLGKIQYLTMVQTATGCTGDPKERLLILFPEDLLFLSVDEERTTVTYEGKLPLAGIQAKEKSTVLGRLQLEITGSLTEPILINCSTAEDYEKLLFHLQKPEKNPDTVTLQPPPIIPKKSWQYHQDVGIH", "length": 363, "header": "tr|A0A8V0ZR99-1|A0A8V0ZR99_CHICK Isoform 1 of PH domain-containing protein OS=Gallus gallus OX=9031 GN=ARHGEF7L PE=4 SV=1 CANONICAL=A0A8V0ZR99-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99/entry#A0A8V0ZDE4-1", "sequence": { "sequence": "MSERYLVLTSFHLLILSVDHTKKAFVYEGLVPLAGMHLREVLTAISCTFEITGPMIESRLICCQNSADFERWIQHLQDQIKMANANYSTSPTSNISFLVPCDEQWKKRELMRHLLCNTILKWEGKPIQHLGKIQYLTMVQTATGCTGDPKERLLILFPEDLLFLSVDEERTTVTYEGKLPLAGIQAKEKSTVLGRLQLEITGSLTEPILINCSTAEDYEKLLFHLQKPEKNPDTVTLQPPPIIPKKSWQYHQDVGIH", "length": 257, "header": "tr|A0A8V0ZDE4-1|A0A8V0ZR99_CHICK Computationally mapped isoform of PH domain-containing protein OS=Gallus gallus OX=9031 GN=ARHGEF7L PE=4 SV=1 CANONICAL=A0A8V0ZR99-1" }, "locus": { "chromosome": "21", "start_pos": 2566610, "end_pos": 2562478, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052383.1", "url": "https://www.ensembl.org/id/ENSGALT00010052383.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031304.1", "url": "https://www.ensembl.org/id/ENSGALP00010031304.1" } ] } }, { "isoform_ac": "A0A8V0ZIW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99/entry#A0A8V0ZIW1-1", "sequence": { "sequence": "MGCCSLSARHAGSAGGSQDEVELLKTGRTRKWSISDAQSEGSLQPKDPAIPTETEGAEALWGRTQEELLNLLIAQPIAGWEGRNILSLGEIIWSSWVFLRSYHMEEMSERYLVLTSFHLLILSVDHTKKAFVYEGLVPLAGMHLREVLTAISCTFEITGPMIESRLICCQNSADFERWIQHLQDQIKMANANYSTSPTSNISFLDPKERLLILFPEDLLFLSVDEERTTVTYEGKLPLAGIQAKEKSTVLGRLQLEITGSLTEPILINCSTAEDYEKLLFHLQKPEKNPDTVTLQPPPIIPKKSWQYHQDVGIH", "length": 314, "header": "tr|A0A8V0ZIW1-1|A0A8V0ZR99_CHICK Computationally mapped isoform of PH domain-containing protein OS=Gallus gallus OX=9031 GN=ARHGEF7L PE=4 SV=1 CANONICAL=A0A8V0ZR99-1" }, "locus": { "chromosome": "21", "start_pos": 2569283, "end_pos": 2562478, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052370.1", "url": "https://www.ensembl.org/id/ENSGALT00010052370.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031296.1", "url": "https://www.ensembl.org/id/ENSGALP00010031296.1" } ] } }, { "isoform_ac": "A0A8V0ZIW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99/entry#A0A8V0ZIW8-1", "sequence": { "sequence": "MGCCSLSARHAGSAGGSQDEVELLKTGRTRKWSISDAQSEGSLQPKDPAIPTETEGAEALWGRTQEELLNLLIAQPIAGWEGRNILSLGEIIWSSWVFLRSYHMEEMSERYLVLTSFHLLILSVDHTKKAFVYEVPCDEQWKKRELMRHLLCNTILKWEGKPIQHLGKIQYLTMVQTATGCTGDPKERLLILFPEDLLFLSVDEERTTVTYEGKLPLAGIQAKEKSTVLGRLQLEITGSLTEPILINCSTAEDYEKLLFHLQKPEKNPDTVTLQPPPIIPKKSWQYHQDVGIH", "length": 293, "header": "tr|A0A8V0ZIW8-1|A0A8V0ZR99_CHICK Computationally mapped isoform of PH domain-containing protein OS=Gallus gallus OX=9031 GN=ARHGEF7L PE=4 SV=1 CANONICAL=A0A8V0ZR99-1" }, "locus": { "chromosome": "21", "start_pos": 2569283, "end_pos": 2562478, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052378.1", "url": "https://www.ensembl.org/id/ENSGALT00010052378.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031301.1", "url": "https://www.ensembl.org/id/ENSGALP00010031301.1" } ] } }, { "isoform_ac": "A0A8V0ZR99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99/entry#A0A8V0ZR99-1", "sequence": { "sequence": "MGCCSLSARHAGSAGGSQDEVELLKTGRTRKWSISDAQSEGSLQPKDPAIPTETEGAEALWGRTQEELLNLLIAQPIAGWEGRNILSLGEIIWSSWVFLRSYHMEEMSERYLVLTSFHLLILSVDHTKKAFVYEGLVPLAGMHLREVLTAISCTFEITGPMIESRLICCQNSADFERWIQHLQDQIKMANANYSTSPTSNISFLVPCDEQWKKRELMRHLLCNTILKWEGKPIQHLGKIQYLTMVQTATGCTGDPKERLLILFPEDLLFLSVDEERTTVTYEGKLPLAGIQAKEKSTVLGRLQLEITGSLTEPILINCSTAEDYEKLLFHLQKPEKNPDTVTLQPPPIIPKKSWQYHQDVGIH", "length": 363, "header": "tr|A0A8V0ZR99-1|A0A8V0ZR99_CHICK Isoform 1 of PH domain-containing protein OS=Gallus gallus OX=9031 GN=ARHGEF7L PE=4 SV=1 CANONICAL=A0A8V0ZR99-1" }, "locus": { "chromosome": "21", "start_pos": 2569283, "end_pos": 2562478, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052362.1", "url": "https://www.ensembl.org/id/ENSGALT00010052362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031290.1", "url": "https://www.ensembl.org/id/ENSGALP00010031290.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZR99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR99" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 187, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 317, "end_pos": 319 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRL0-1", "uniprot_ac": "A0A8V0ZRL0", "uniprot_id": "A0A8V0ZRL0_CHICK", "mass": { "chemical_mass": 146514.0, "monoisotopic_mass": 146514.0 }, "refseq": {}, "gene_names": [ { "name": "SORBS1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" } ] } ], "protein_names": [ { "name": "Sorbin and SH3 domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SORBS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0", "locus": { "chromosome": "6", "start_pos": 17210949, "end_pos": 17047483, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021617", "url": "https://www.ensembl.org/id/ENSGALG00010021617" } ] } } ], "crossref": [ { "id": "cd11916", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11916", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11919", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11919", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11922", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11922", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDP1", "url": "https://www.orthodb.org/?gene=A0A8V0ZDP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDQ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZDQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-445355", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445355", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZDP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJ51-1", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSEREEVDVAKTVVNGLSSNGQEKAVDVPLYTRSISAVTIIPVKKVKTSPHLVLPTETDPTKVCSGKGAVTLWASPASEENQKISSPCPQDAEKPENDWRSSPNTDANGDAQPSSLAAKGYRSVRPNLSSDSKPQDATATTTQPGVIVVPLVQINPDRQQEGSSSTPPPPLVPFGQGSVFPETVPPGTPLTFPTLDDFIPPHLQRGSHHNQAPSASGTSPSVYPKLPFFSTPPSLVPPVTGALHRGLKPEITGVISRTDPGPALNEVTQPSSGTDYPSSFTSINKSSSAYPSTTIVNPTIVLLQHNREQQKRLSSLADSVPDRLVSDKVDLALTQVKPLQEPVLSERRVLEEKRRIVKSPQHMADTSVDDIGIPLRNTDRSKDWYKTMFKQIHKLNRDTPEENPYCPTYIFPELPEIQQKPEEDNPYSPTYQFPASTPSPISEDEDSDSYSPRYSYCEDTRSQPSVPRSKSEMDHIDSEKVFKRSATLPLPNRTSSLKSSPERTDWEPPDKKVDTRKYRAEPRSIYDYQPGKSSVLNSEKMTRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILTREDRKTDLEKDLYLYQTELEADLEKMEKLYKAPHKKPQKNTAGVTPLETSTDHSSYSTYSPNYHAAKRDSEPALGDLAGLENERQIYKSVLEGGDIPFQGLSGLKRPSSSASTKDSESPRHFAPVDYMETPEEIIRRRYDDKEKLLEDQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNVDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRSYIELLPPAEKAQPKKPLPLQVLEYGDAIAKFNFNGDTQVEMSFRKGERITLIRRVDENWYEGRISGTSRQGIFPVTYVEVLKRPVVKNAIDYPDPPVSLSPNRSMTASPQSPSSELLHTPTPPPLPFSRRALSPEVQAVTSEWIALTVGVSPSTTPALTAPLPSLPEASLSHTDSLSPPTVASPSPSFSLPHSHLSGSSTPRSIKSPLPSYSSGPQPSTHSFYQAAPQSKEKVGGSSSPCPHWAGRSPESTLTEQHGTPGSQAWLQKTREGSSNPEQGSHAAPNVSVERCLKPSQLDMRASPERRPVSSSEDNQLCQELMAIVQGGKAEKRGTRRGDLGKFQGGEKKTADSKAFSSPAPLSSSALSSSTVTTQPPPRLTRRVNKPQPSLHSLRAGPDLTESEKSYVQPQAQQQGASPDRSQTPRDIVSYQALYSYTPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKLLYL", "length": 1322, "header": "tr|A0A8V0ZRL0-1|A0A8V0ZRL0_CHICK Isoform 1 of Sorbin and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=SORBS1 PE=1 SV=1 CANONICAL=A0A8V0ZRL0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0/entry#A0A8V0ZDP1-1", "sequence": { "sequence": "MSSEREEVDVAKTVVNGLSSNGQEKAVDVPLYTRSISAVTIIPVKKVKTSPHLVLPTETDPTKVCSGKGAVTLWASPASEENQKISSPCPQDAEKPENDWRSSPNTDANGDAQPSSLAAKGYRSVRPNLSSDSKPQDATATTTQPGVIVVPLVQINPDRQQEGSSSTPPPPLVPFGQGSVFPETVPPGTPLTFPTLDDFIPPHLQRGSHHNQAPSASGTSPSVYPKLPFFSTPPSLVPPVTGALHRGLKPEITGVISRTDPGPALNEVTQPSSGTDYPSSFTSINKSSSAYPSTTIVNPTIVLLQHNREQQKRLSSLADSVPDRLVSDKVDLALTQVKPLQEPVLSERRVLEEKRRIVKSPQHMADTSVDDIGIPLRNTDRSKDWYKTMFKQIHKLNRDTPEENPYCPTYIFPELPEIQQKPEEDNPYSPTYQFPASTPSPISEDEDSDSYSPRYSYCEDTRSQPSVPRSKSEMDHIDSEKVFKRSATLPLPNRTSSLKSSPERTDWEPPDKKVDTRKYRAEPRSIYDYQPGKSSVLNSEKMTRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILTREDRKNTAGVTPLETSTDHSSYSTYSPNYHAAKRDSEPALGDLAGLENERQIYKSVLEGGDIPFQGLSGLKRPSSSASTKDSESPRHFAPVDYMETPEEIIRRRYDDKEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRSYIELLPPAEKAQPKKPLPLQVLEYGDAIAKFNFNGDTQVEMSFRKGERITLIRRVDENWYEGRISGTSRQGIFPVTYVEVLKRPVVKNAIDYPDPPVSLSPNRSMTASPQSPSSELLHTPTPPPLPFSRRALSPEVQAVTSEWIALTVGVSPSTTPALTAPLPSLPEASLSHTDSLSPPTVASPSPSFSLPHSHLSGSSTPRSIKSPLPSYSSGPQPSTHSFYQAAPQSKEKVGGSSSPCPHWAGRSPESTLTEQHGTPGSQAWLQKTREGSSNPEQGSHAAPNVSVERCLKPSQLDMRASPERRPVSSSEDNQLCQELMAIVQGGKAEKRGTRRGDLGKFQGGEKKTADSKAFSSPAPLSSSALSSSTVTTQPPPRLTRRVNKPQPSLHSLRAGPDLTESEKSYVQPQAQQQGASPDRSQTPRDIVSYQALYSYTPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKLLYL", "length": 1232, "header": "tr|A0A8V0ZDP1-1|A0A8V0ZRL0_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=SORBS1 PE=1 SV=1 CANONICAL=A0A8V0ZRL0-1" }, "locus": { "chromosome": "6", "start_pos": 17208859, "end_pos": 17143655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052501.1", "url": "https://www.ensembl.org/id/ENSGALT00010052501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031408.1", "url": "https://www.ensembl.org/id/ENSGALP00010031408.1" } ] } }, { "isoform_ac": "A0A8V0ZDQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0/entry#A0A8V0ZDQ2-1", "sequence": { "sequence": "MSSEREEVDVAKTVVNGLSSNGQEKAVDVPLYTRSISAVTIIPVKKVKTSPHLVLPTETDPTKVCSGKGAVTLWASPASEENQKISSPCPQDAEKPENDWRSSPNTDANGDAQPSSLAAKGYRSVRPNLSSDSKPQDATATTTQPGVIVVPLVQINPDRQQEGSSSTPPPPLVPFGQGSVFPETVPPGTPLTFPTLDDFIPPHLQRGSHHNQAPSASGTSPSVYPKLPFFSTPPSLVPPVTGALHRGLKPEITGVISRTDPGPALNEVTQPSSGTDYPSSFTSINKSSSAYPSTTIVNPTIVLLQHNREQQKRLSSLADSVPDRLVSDKVDLALTQVKPLQEPVLSERRVLEEKRRIVKSPQHMADTSVDDIGIPLRNTDRSKDWYKTMFKQIHKLNRDTPEENPYCPTYIFPELPEIQQKPEEDNPYSPTYQFPASTPSPISEDEDSDSYSPRYSYCEDTRSQPSVPRSKSEMDHIDSEKVFKRSATLPLPNRTSSLKSSPERTDWEPPDKKVDTRKYRAEPRSIYDYQPGKSSVLNSEKMTRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILTREDRKTDLEKDLYLYQTELEADLEKMEKLYKAPHKKPQKNTAGVTPLETSTDHSSYSTYSPNYHAAKRDSEPALGDLAGLENERQIYKSVLEGGDIPFQGLSGLKRPSSSASTKDSESPRHFAPVDYMETPEEIIRRRYDDKEKLLEDQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNVDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRSYIELLPPAEKAQPKKPLPLQVLEYGDAIAKFNFNGDTQVEMSFRKGERITLIRRVDENWYEGRISGTSRQGIFPVTYVEVLKRPVVKNAIDYPDPPVSLSPNRSMTASPQSPSSELLHTPTPPPLPFSRRALSPEVQAVTSEWIALTVGVSPSTTPALTAPLPSLPEASLSHTDSLSPPTVASPSPSFSLPHSHLSGSSTPRSIKSPLPSYSSGPQPSTHSFYQAAPQSKEKVGGSSSPCPHWAGRSPESTLTEQHGTPGSQAWLQKTREGSSNPEQGSHAAPNVSVERCLKPSQLDMRASPERRPVSSSEDNQLCQELMAIVQGGKAEKRGTRRGDLGKFQGGEKKTADSKAFSSPAPLSSSALSSSTVTTQPPPRLTRRVNKPQQPQAQQQGASPDRSQTPRDIVSYQALYSYTPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKLLYL", "length": 1302, "header": "tr|A0A8V0ZDQ2-1|A0A8V0ZRL0_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=SORBS1 PE=1 SV=1 CANONICAL=A0A8V0ZRL0-1" }, "locus": { "chromosome": "6", "start_pos": 17208859, "end_pos": 17143655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052511.1", "url": "https://www.ensembl.org/id/ENSGALT00010052511.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031418.1", "url": "https://www.ensembl.org/id/ENSGALP00010031418.1" } ] } }, { "isoform_ac": "A0A8V0ZJ51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0/entry#A0A8V0ZJ51-1", "sequence": { "sequence": "MDCVYLNAPKPSAQRASLNASARCYFSSPTPYGAVPSGKQALPAGHFPSSGPRDMVHVGQPLLESSSSSNASSLQRNPDRADPSSKAGMNSSHETKADKKVSRLYVACLSNNTCSATSENSTGTTHDPSASTSLGAEVTQAPATDIVFSATGKALPAPPPPPIPPRPYFYIVLNKDAVSSDPGQPSWTQSSPPQALRDRVLEPQSTAATQDRMRKEPYLTQQRQPPYKAVGRSMDATATTTQPGVIVVPLVQINPDRQQEGSSSTPPPPLVPFGQGSVFPETVPPGTPLTFPTLDDFIPPHLQRGSHHNQAPSASGTSPSVYPKLPFFSTPPSLVPPVTGALHRGLKPEITGVISRTDPGPALNEVTQPSSGTDYPSSFTSINKSSSAYPSTTIVNPTIVLLQHNREQQKRLSSLADSVPDRLVSDKVDLALTQVKPLQEPVLSERRVLEEKRRIVKSPQHMADTSVDDIGIPLRNTDRSKDWYKTMFKQIHKLNRDEDSDSYSPRYSYCEDTRSQPSVPRSKSEMDHIDSEKVFKRSATLPLPNRTSSLKSSPERTDWEPPDKKVDTRKYRAEPRSIYDYQPGKSSVLNSEKMTDLEKDLYLYQTELEADLEKMEKLYKAPHKKPQKNTAGVTPLETSTDHSSYSTYSPNYHAAKRDSEPALGDLAGLENERQIYKSVLEGGDIPFQGLSGLKRPSSSASTKDSESPRHFAPVDYMETPEEIIRRRYDDKEKLLEDQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNVDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRSYIELLPPAEKAQPKKPLPLQVLEYGDAIAKFNFNGDTQVEMSFRKGERITLIRRVDENWYEGRISGTSRQGIFPVTYVEVLKRPVVKNAIDYPDPPVSLSPNRSMTASPQSPSSELLHTPTPPPLPFSRRALSPEVQAVTSEWIALTVGVSPSTTPALTAPLPSLPEASLSHTDSLSPPTVASPSPSFSLPHSHLSGSSTPRSIKSPLPSYSSGPQPSTHSFYQAAPQSKEKVGGSSSPCPHWAGRSPESTLTEQHGTPGSQAWLQKTREGSSNPEQGSHAAPNVSVERCLKPSQLDMRASPERRPVSSSEDNQLCQELMAIVQGGKAEKRGTRRGDLGKFQGGEKKTADSKAFSSPAPLSSSALSSSTVTTQPPPRLTRRVNKPQQPQAQQQGASPDRSQTPRDIVSYQALYSYTPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKLLYL", "length": 1304, "header": "tr|A0A8V0ZJ51-1|A0A8V0ZRL0_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=SORBS1 PE=1 SV=1 CANONICAL=A0A8V0ZRL0-1" }, "locus": { "chromosome": "6", "start_pos": 17208859, "end_pos": 17155593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052484.1", "url": "https://www.ensembl.org/id/ENSGALT00010052484.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031390.1", "url": "https://www.ensembl.org/id/ENSGALP00010031390.1" } ] } }, { "isoform_ac": "A0A8V0ZJ62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0/entry#A0A8V0ZJ62-1", "sequence": { "sequence": "MSSEREEVDVAKTVVNGLSSNGQEKETDPTKVCSGKGAVTLWASPASEENQKISSPCPQDAEKPENDWRSSPNTDANGDAQPSSLAAKGYRSVRPNLSSDSKPQDPGPALNEVTQPSSGTDYPSSFTSINKSSSAYPSTTIVNPTIVLLQHNREQQKRLSSLADSVPDRLVSDKVDLALTQVKPLQEPVLSERRVLEEKRRIVKSPQHMADTSVDDIGIPLRNTDRSKDWYKTMFKQIHKLNRDTPEENPYCPTYIFPELPEIQQKPEEDNPYSPTYQFPASTPSPISEDEDSDSYSPRYSYCEDTRSQPSVPRSKSEMDHIDSEKVFKRSATLPLPNRTSSLKSSPERTDWEPPDKKVDTRKYRAEPRSIYDYQPGKSSVLNSEKMTRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILTREDRKTDLEKDLYLYQTELEADLEKMEKLYKAPHKKPQKNTAGVTPLETSTDHSSYSTYSPNYHAAKRDSEPALGDLAGLENERQIYKSVLEGGDIPFQGLSGLKRPSSSASTKDSESPRHFAPVDYMETPEEIIRRRYDDKEKLLEDQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNVDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRSYIELLPPAEKAQPKKPLPLQVLEYGDAIAKFNFNGDTQVEMSFRKGERITLIRRVDENWYEGRISGTSRQGIFPVTYVEVLKRPVVKNAIDYPDPPVSLSPNRSMTASPQSPSSELLHTPTPPPLPFSRRALSPEVQAVTSEWIALTVGVSPSTTPALTAPLPSLPEASLSHTDSLSPPTVASPSPSFSLPHSHLSGSSTPRSIKSPLPSYSSGPQPSTHSFYQAAPQSKEKVGGSSSPCPHWAGRSPESTLTEQHGTPGSQAWLQKTREGSSNPEQGSHAAPNVSVERCLKPSQLDMRASPERRPVSSSEDNQLCQELMAIVQGGKAEKRGTRRGDLGKFQGGEKKTADSKAFSSPAPLSSSALSSSTVTTQPPPRLTRRVNKPQPSLHSLRAGPDLTESEKSYVQPQAQQQGASPDRSQTPRDIVSYQALYSYTPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKLLYL", "length": 1167, "header": "tr|A0A8V0ZJ62-1|A0A8V0ZRL0_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=SORBS1 PE=1 SV=1 CANONICAL=A0A8V0ZRL0-1" }, "locus": { "chromosome": "6", "start_pos": 17208859, "end_pos": 17143655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052493.1", "url": "https://www.ensembl.org/id/ENSGALT00010052493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031400.1", "url": "https://www.ensembl.org/id/ENSGALP00010031400.1" } ] } }, { "isoform_ac": "A0A8V0ZJ68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0/entry#A0A8V0ZJ68-1", "sequence": { "sequence": "MSSEREEVDVAKTVVNGLSSNGQEKETDPTKVCSGKGAVTLWASPASEENQKISSPCPQDAEKPENDWRSSPNTDANGDAQPSSLAAKGYRSVRPNLSSDSKPQDATATTTQPGVIVVPLVQINPDRQQEGSSSTPPPPLVPFGQGSVFPETVPPGTPLTFPTLDDFIPPHLQRGSHHNQAPSASGTSPSVYPKLPFFSTPPSLVPPVTGALHRGLKPEITGVISRTDPGPALNEVTQPSSGTDYPSSFTSINKSSSAYPSTTIVNPTIVLLQHNREQQKRLSSLADSVPDRLVSDKVDLALTQVKPLQEPVLSERRVLEEKRRIVKSPQHMADTSVDDIGIPLRNTDRSKDWYKTMFKQIHKLNRDTPEENPYCPTYIFPELPEIQQKPEEDNPYSPTYQFPASTPSPISEDEDSDSYSPRYSYCEDTRSQPSVPRSKSEMDHIDSEKVFKRSATLPLPNRTSSLKSSPERTDWEPPDKKVDTRKYRAEPRSIYDYQPGKSSVLNSEKMTRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILTREDRKNTAGVTPLETSTDHSSYSTYSPNYHAAKRDSEPALGDLAGLENERQIYKSVLEGGDIPFQGLSGLKRPSSSASTKDSESPRHFAPVDYMETPEEIIRRRYDDKEKLLEDQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNVDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRSYIELLPPAEKAQPKKPLPLQVLEYGDAIAKFNFNGDTQVEMSFRKGERITLIRRVDENWYEGRISGTSRQGIFPVTYVEVLKRPVVKNAIDYPDPPVSLSPNRSMTASPQSPSSELLHTPTPPPLPFSRRALSPEVQAVTSEWIALTVGVSPSTTPALTAPLPSLPEASLSHTDSLSPPTVASPSPSFSLPHSHLSGSSTPRSIKSPLPSYSSGPQPSTHSFYQAAPQSKEKVGGSSSPCPHWAGRSPESTLTEQHGTPGSQAWLQKTREGSSNPEQGSHAAPNVSVERCLKPSQLDMRASPERRPVSSSEDNQLCQELMAIVQGGKAEKRGTRRGDLGKFQGGEKKTADSKAFSSPAPLSSSALSSSTVTTQPPPRLTRRVNKPQPSLHSLRAGPDLTESEKSYVQPQAQQQGASPDRSQTPRDIVSYQALYSYTPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKLLYL", "length": 1256, "header": "tr|A0A8V0ZJ68-1|A0A8V0ZRL0_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=SORBS1 PE=1 SV=1 CANONICAL=A0A8V0ZRL0-1" }, "locus": { "chromosome": "6", "start_pos": 17208859, "end_pos": 17143655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052498.1", "url": "https://www.ensembl.org/id/ENSGALT00010052498.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031405.1", "url": "https://www.ensembl.org/id/ENSGALP00010031405.1" } ] } }, { "isoform_ac": "A0A8V0ZKR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0/entry#A0A8V0ZKR4-1", "sequence": { "sequence": "MDCVYLNAPKPSAQRASLNASARCYFSSPTPYGAVPSGKQALPAGHFPSSGPRDMVHVGQPLLESSSSSNASSLQRNPDRADPSSKAGMNSSHETKADKKVSRLYVACLSNNTCSATSENSTGTTHDPSASTSLGAEVTQAPATDIVFSATGKALPAPPPPPIPPRPYFYIVLNKDAVSSDPGQPSWTQSSPPQALRDRVLEPQSTAATQDRMRKEPYLTQQRQPPYKAVGRSMDATATTTQPGVIVVPLVQINPDRQQEGSSSTPPPPLVPFGQGSVFPETVPPGTPLTFPTLDDFIPPHLQRGSHHNQAPSASGTSPSVYPKLPFFSTPPSLVPPVTGALHRGLKPEITGVISRTDPGPALNEVTQPSSGTDYPSSFTSINKSSSAYPSTTIVNPTIVLLQHNREQQKRLSSLADSVPDRLVSDKVDLALTQVKPLQEPVLSERRVLEEKRRIVKSPQHMADTSVDDIGIPLRNTDRSKDWYKTMFKQIHKLNRDEDSDSYSPRYSYCEDTRSQPSVPRSKSEMDHIDSEKVFKRSATLPLPNRTSSLKSSPERTDWEPPDKKVDTRKYRAEPRSIYDYQPGKSSVLNSEKMTDLEKDLYLYQTELEADLEKMEKLYKAPHKKPQKNTAGVTPLETSTDHSSYSTYSPNYHAAKRDSEPALGDLAGLENERQIYKSVLEGGDIPFQGLSGLKRPSSSASTKDSESPRHFAPVDYMETPEEIIRRRYDDKEKLLEDQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNVDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRSYIELLPPAEKAQPKKPLPLQVLEYGDAIAKFNFNGDTQVEMSFRKGERITLIRRVDENWYEGRISGTSRQGIFPVTYVEVLKRPVVKNAIDYPDPPVSLSPNRSMTASPQQPQAQQQGASPDRSQTPRDIVSYQALYSYTPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKLLYL", "length": 1028, "header": "tr|A0A8V0ZKR4-1|A0A8V0ZRL0_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=SORBS1 PE=1 SV=1 CANONICAL=A0A8V0ZRL0-1" }, "locus": { "chromosome": "6", "start_pos": 17208859, "end_pos": 17155593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052485.1", "url": "https://www.ensembl.org/id/ENSGALT00010052485.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031392.1", "url": "https://www.ensembl.org/id/ENSGALP00010031392.1" } ] } }, { "isoform_ac": "A0A8V0ZL09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0/entry#A0A8V0ZL09-1", "sequence": { "sequence": "MSSEREEVDVAKTVVNGLSSNGQEKAVDVPLYTRSISAVTIIPVKKVKTSPHLVLPTETDPTKVCSGKGAVTLWASPASEENQKISSPCPQDAEKPENDWRSSPNTDANGDAQPSSLAAKGYRSVRPNLSSDSKPQDATATTTQPGVIVVPLVQINPDRQQEGSSSTPPPPLVPFGQGSVFPETVPPGTPLTFPTLDDFIPPHLQRGSHHNQAPSASGTSPSVYPKLPFFSTPPSLVPPVTGALHRGLKPEITGVISRTDPGPALNEVTQPSSGTDYPSSFTSINKSSSAYPSTTIVNPTIVLLQHNRDSVPDRLVSDKVDLALTQVKPLQEPVLSERRVLEEKRRIVKSPQHMADTSVDDIGIPLRNTDRSKDWYKTMFKQIHKLNRDEDSDSYSPRYSYCEDTRSQPSVPRSKSEMDHIDSEKVFKRSATLPLPNRTSSLKSSPERTDWEPPDKKVDTRKYRAEPRSIYDYQPGKSSVLNSEKMTRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILTREDRKTDLEKDLYLYQTELEADLEKMEKLYKAPHKKPQKNTAGVTPLETSTDHSSYSTYSPNYHAAKRDSEPALGDLAGLENERQIYKSVLEGGDIPFQGLSGLKRPSSSASTKDSESPRHFAPVDYMETPEEIIRRRYDDKEKLLEDQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNVDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRSYIELLPPAEKAQPKKPLPLQVLEYGDAIAKFNFNGDTQVEMSFRKGERITLIRRVDENWYEGRISGTSRQGIFPVTYVEVLKRPVVKNAIDYPDPPVSLSPNRSMTASPQSPSSELLHTPTPPPLPFSRRALSPEVQAVTSEWIALTVGVSPSTTPALTAPLPSLPEASLSHTDSLSPPTVASPSPSFSLPHSHLSGSSTPRSIKSPLPSYSSGPQPSTHSFYQAAPQSKEKVGGSSSPCPHWAGRSPESTLTEQHGTPGSQAWLQKTREGSSNPEQGSHAAPNVSVERCLKPSQLDMRASPERRPVSSSEDNQLCQELMAIVQGGKAEKRGTRRGDLGKFQGGEKKTADSKAFSSPAPLSSSALSSSTVTTQPPPRLTRRVNKPQPSLHSLRAGPDLTESEKSYVQPQAQQQGASPDRSQTPRDIVSYQALYSYTPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKLLYL", "length": 1266, "header": "tr|A0A8V0ZL09-1|A0A8V0ZRL0_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=SORBS1 PE=1 SV=1 CANONICAL=A0A8V0ZRL0-1" }, "locus": { "chromosome": "6", "start_pos": 17208859, "end_pos": 17143655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052516.1", "url": "https://www.ensembl.org/id/ENSGALT00010052516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031422.1", "url": "https://www.ensembl.org/id/ENSGALP00010031422.1" } ] } }, { "isoform_ac": "A0A8V0ZRJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0/entry#A0A8V0ZRJ2-1", "sequence": { "sequence": "MSSEREEVDVAKTVVNGLSSNGQEKETDPTKVCSGKGAVTLWASPASEENQKISSPCPQDAEKPENDWRSSPNTDANGDAQPSSLAAKGYRSVRPNLSSDSKPQALPPPRPPLPKEESFAWRPRTDTKATNLLPVPIMDCVYLNAPKPSAQRASLNASARCYFSSPTPYGAVPSGKQALPAGHFPSSGPRDMVHVGQPLLESSSSSNASSLQRNPDRADPSSKAGMNSSHETKADKKVSRLYVACLSNNTCSATSENSTGTTHDPSASTSLGAEVTQAPATDIVFSATGKALPAPPPPPIPPRPYFYIVLNKDAVSSDPGQPSWTQSSPPQALRDRVLEPQSTAATQDRMRKEPYLTQQRQPPYKAVGRSMDATATTTQPGVIVVPLVQINPDRQQEGSSSTPPPPLVPFGQGSVFPETVPPGTPLTFPTLDDFIPPHLQRGSHHNQAPSASGTSPSVYPKLPFFSTPPSLVPPVTGALHRGLKPEITGVISRTDPGPALNEVTQPSSGTDYPSSFTSINKSSSAYPSTTIVNPTIVLLQHNREQQKRLSSLADSVPDRLVSDKVDLALTQVKPLQEPVLSERRVLEEKRRIVKSPQHMADTSVDDIGIPLRNTDRSKDWYKTMFKQIHKLNRDEDSDSYSPRYSYCEDTRSQPSVPRSKSEMDHIDSEKVFKRSATLPLPNRTSSLKSSPERTDWEPPDKKVDTRKYRAEPRSIYDYQPGKSSVLNSEKMTDLEKDLYLYQTELEADLEKMEKLYKAPHKKPQKNTAGVTPLETSTDHSSYSTYSPNYHAAKRDSEPALGDLAGLENERQIYKSVLEGGDIPFQGLSGLKRPSSSASTKDSESPRHFAPVDYMETPEEIIRRRYDDKEKLLEDQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNVDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRSYIELLPPAEKAQPKKPLPLQVLEYGDAIAKFNFNGDTQVEMSFRKGERITLIRRVDENWYEGRISGTSRQGIFPVTYVEVLKRPVVKNAIDYPDPPVSLSPNRSMTASPQPSLHSLRAGPDLTESEKSYVQPQAQQQGASPDRSQTPRDIVSYQALYSYTPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKLLYL", "length": 1185, "header": "tr|A0A8V0ZRJ2-1|A0A8V0ZRJ2_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=SORBS1 PE=1 SV=1 CANONICAL=A0A8V0ZRL0-1" }, "locus": { "chromosome": "6", "start_pos": 17208859, "end_pos": 17143655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052487.1", "url": "https://www.ensembl.org/id/ENSGALT00010052487.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031394.1", "url": "https://www.ensembl.org/id/ENSGALP00010031394.1" } ] } }, { "isoform_ac": "A0A8V0ZRJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0/entry#A0A8V0ZRJ9-1", "sequence": { "sequence": "MSSEREEVDVAKTVVNGLSSNGQEKAVDVPLYTRSISAVTIIPVKKVKTSPHLVLPTETDPTKVCSGKGAVTLWASPASEENQKISSPCPQDAEKPENDWRSSPNTDANGDAQPSSLAAKGYRSVRPNLSSDSKPQDATATTTQPGVIVVPLVQINPDRQQEGSSSTPPPPLVPFGQGSVFPETVPPGTPLTFPTLDDFIPPHLQRGSHHNQAPSASGTSPSVYPKLPFFSTPPSLVPPVTGALHRGLKPEITGVISRTDPGPALNEVTQPSSGTDYPSSFTSINKSSSAYPSTTIVNPTIVLLQHNREQQKRLSSLADSVPDRLVSDKVDLALTQVKPLQEPVLSERRVLEEKRRIVKSPQHMADTSVDDIGIPLRNTDRSKDWYKTMFKQIHKLNRDTPEENPYCPTYIFPELPEIQQKPEEDNPYSPTYQFPASTPSPISEDEDSDSYSPRYSYCEDTRSQPSVPRSKSEMDHIDSEKVFKRSATLPLPNRTSSLKSSPERTDWEPPDKKVDTRKYRAEPRSIYDYQPGKSSVLNSEKMTRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILTREDRKNTAGVTPLETSTDHSSYSTYSPNYHAAKRDSEPALGDLAGLENERQIYKSVLEGGDIPFQGLSGLKRPSSSASTKDSESPRHFAPVDYMETPEEIIRRRYDDKEKLLEDQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNVDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRSYIELLPPAEKAQPKKPLPLQVLEYGDAIAKFNFNGDTQVEMSFRKGERITLIRRVDENWYEGRISGTSRQGIFPVTYVEVLKRPVVKNAIDYPDPPVSLSPNRSMTASPQSPSSELLHTPTPPPLPFSRRALSPEVQAVTSEWIALTVGVSPSTTPALTAPLPSLPEASLSHTDSLSPPTVASPSPSFSLPHSHLSGSSTPRSIKSPLPSYSSGPQPSTHSFYQAAPQSKEKVGGSSSPCPHWAGRSPESTLTEQHGTPGSQAWLQKTREGSSNPEQGSHAAPNVSVERCLKPSQLDMRASPERRPVSSSEDNQLCQELMAIVQGGKAEKRGTRRGDLGKFQGGEKKTADSKAFSSPAPLSSSALSSSTVTTQPPPRLTRRVNKPQPSLHSLRAGPDLTESEKSYVQPQAQQQGASPDRSQTPRDIVSYQALYSYTPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKLLYL", "length": 1288, "header": "tr|A0A8V0ZRJ9-1|A0A8V0ZRJ9_CHICK Computationally mapped isoform of Sorbin and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=SORBS1 PE=1 SV=1 CANONICAL=A0A8V0ZRL0-1" }, "locus": { "chromosome": "6", "start_pos": 17208859, "end_pos": 17143655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052497.1", "url": "https://www.ensembl.org/id/ENSGALT00010052497.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031404.1", "url": "https://www.ensembl.org/id/ENSGALP00010031404.1" } ] } }, { "isoform_ac": "A0A8V0ZRL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0/entry#A0A8V0ZRL0-1", "sequence": { "sequence": "MSSEREEVDVAKTVVNGLSSNGQEKAVDVPLYTRSISAVTIIPVKKVKTSPHLVLPTETDPTKVCSGKGAVTLWASPASEENQKISSPCPQDAEKPENDWRSSPNTDANGDAQPSSLAAKGYRSVRPNLSSDSKPQDATATTTQPGVIVVPLVQINPDRQQEGSSSTPPPPLVPFGQGSVFPETVPPGTPLTFPTLDDFIPPHLQRGSHHNQAPSASGTSPSVYPKLPFFSTPPSLVPPVTGALHRGLKPEITGVISRTDPGPALNEVTQPSSGTDYPSSFTSINKSSSAYPSTTIVNPTIVLLQHNREQQKRLSSLADSVPDRLVSDKVDLALTQVKPLQEPVLSERRVLEEKRRIVKSPQHMADTSVDDIGIPLRNTDRSKDWYKTMFKQIHKLNRDTPEENPYCPTYIFPELPEIQQKPEEDNPYSPTYQFPASTPSPISEDEDSDSYSPRYSYCEDTRSQPSVPRSKSEMDHIDSEKVFKRSATLPLPNRTSSLKSSPERTDWEPPDKKVDTRKYRAEPRSIYDYQPGKSSVLNSEKMTRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILTREDRKTDLEKDLYLYQTELEADLEKMEKLYKAPHKKPQKNTAGVTPLETSTDHSSYSTYSPNYHAAKRDSEPALGDLAGLENERQIYKSVLEGGDIPFQGLSGLKRPSSSASTKDSESPRHFAPVDYMETPEEIIRRRYDDKEKLLEDQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNVDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRSYIELLPPAEKAQPKKPLPLQVLEYGDAIAKFNFNGDTQVEMSFRKGERITLIRRVDENWYEGRISGTSRQGIFPVTYVEVLKRPVVKNAIDYPDPPVSLSPNRSMTASPQSPSSELLHTPTPPPLPFSRRALSPEVQAVTSEWIALTVGVSPSTTPALTAPLPSLPEASLSHTDSLSPPTVASPSPSFSLPHSHLSGSSTPRSIKSPLPSYSSGPQPSTHSFYQAAPQSKEKVGGSSSPCPHWAGRSPESTLTEQHGTPGSQAWLQKTREGSSNPEQGSHAAPNVSVERCLKPSQLDMRASPERRPVSSSEDNQLCQELMAIVQGGKAEKRGTRRGDLGKFQGGEKKTADSKAFSSPAPLSSSALSSSTVTTQPPPRLTRRVNKPQPSLHSLRAGPDLTESEKSYVQPQAQQQGASPDRSQTPRDIVSYQALYSYTPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKLLYL", "length": 1322, "header": "tr|A0A8V0ZRL0-1|A0A8V0ZRL0_CHICK Isoform 1 of Sorbin and SH3 domain containing 1 OS=Gallus gallus OX=9031 GN=SORBS1 PE=1 SV=1 CANONICAL=A0A8V0ZRL0-1" }, "locus": { "chromosome": "6", "start_pos": 17208859, "end_pos": 17143655, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052507.1", "url": "https://www.ensembl.org/id/ENSGALT00010052507.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031414.1", "url": "https://www.ensembl.org/id/ENSGALP00010031414.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 167, "start_aa": "Thr", "end_pos": 167, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr167", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-445355", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-445355", "resource": "Reactome", "description": "Smooth Muscle Contraction" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" } ], "pmid": "" }, { "name": "cell-substrate junction", "id": "GO:0030055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "insulin receptor binding", "id": "GO:0005158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" } ], "pmid": "" }, { "name": "signaling receptor complex adaptor activity", "id": "GO:0030159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030159", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" } ], "pmid": "" }, { "name": "cell-substrate adhesion", "id": "GO:0031589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031589", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1121, "end_pos": 1123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 939, "end_pos": 941, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 785, "end_pos": 844, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZRL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL0" }, { "id": "PS50831", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50831" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SoHo", "eco_id": "ECO_0000259", "start_pos": 357, "end_pos": 415, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 167 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1121, "end_pos": 1123 }, { "start_pos": 128, "end_pos": 130 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 493, "end_pos": 495 }, { "start_pos": 939, "end_pos": 941 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRM6-1", "uniprot_ac": "A0A8V0ZRM6", "uniprot_id": "A0A8V0ZRM6_CHICK", "mass": { "chemical_mass": 217023.0, "monoisotopic_mass": 217023.0 }, "refseq": { "ac": "XP_040506765", "name": "nuclear receptor coactivator 6 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506765" }, "gene_names": [ { "name": "NCOA6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6" } ] }, { "name": "NCOA6", "type": "synonym", "evidence": [ { "id": "XP_040506765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506765" } ] } ], "protein_names": [ { "name": "Nuclear receptor coactivator 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6/entry#names_and_taxonomy" } ] }, { "name": "nuclear receptor coactivator 6 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040506765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506765" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040506765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506765" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NCOA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6", "locus": { "chromosome": "20", "start_pos": 877247, "end_pos": 831234, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021627", "url": "https://www.ensembl.org/id/ENSGALG00010021627" } ] } } ], "crossref": [ { "id": "419122", "url": "https://www.ncbi.nlm.nih.gov/gene/419122", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDS7", "url": "https://www.orthodb.org/?gene=A0A8V0ZDS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKV6", "url": "https://www.orthodb.org/?gene=A0A8V0ZKV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKW1", "url": "https://www.orthodb.org/?gene=A0A8V0ZKW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL30", "url": "https://www.orthodb.org/?gene=A0A8V0ZL30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRM6", "url": "https://www.orthodb.org/?gene=A0A8V0ZRM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15690:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15690:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040506765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040506765", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKW1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDWFPLLDTMVLDDLPNLGDTCASLYSLAMEDLEVDLDSGVEEDELKQEVAPEDSTIFVAFKGDIGDRDFEQKLSVILENVPGLLHMESNKLKLQKIEPWNSVRVTFNIPREAAERLRILAQNNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRINGPLGANNSVRMETGFPMQGGQGLIRMSNAAAVMMSQSGSVPSSMVAGGASTELQPRAPRPSSQPDAMDPLLSGLNIQQQNHPSGSLAPQLHSMQSVPVNRQMNSANFQQLQQQTQLQTRPPQPHQQPQQGIRPSFTSPAQVPVPPGWNQLPSGALQPPPTQGALGTLTVNQGWKKAPLPGQMQQQLQARPSLATVQTPTHPPPPYPFGSQQASQAHSNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQSSTLPQGFQQTVSSPSRNPMVQQGNVPPNFMVMQQQNQGPQGLHPGLGGMPKRLPPGFPAGQANQSFMQGQVPSTAPGTPVNSGAPQLQTSQNVQHTGGQGSGPPQNQMQAPHGPPNMMQTNLMGLHGNMNNQQAGASGVPQVNMSNIQGQPQQGPQSQLMGMHQQIVSSQGQMVNIQAQGSMNPQNQMILSRSQLMPQGQMMVTPQSQNLGPSPQRMTPPKQMISQQGQQMMSTHNQMMGPQGQVLLQPNSMMEQMMTTQMQGNKQPFNTQNQSSVMSGPAQLMRGPTPNMQGNMVQFSGQMMAQQGPVNGNPSQVMGIQGQVLRPTGPGPHMSQQLGDTTTATNNDVNMTQMLPDVPVQQSNMVPSHMQAMQGNNSSSGSHFSGHGLPFNSGFSGTPNGNQISCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKPNSQNASKPKKKKPPRKKKTNQQLEQTNSSEPRPGGLEESDQSSTSGDQGINLDNSGPKLSDFGSRPPGYPSQPVEQRPLQQMPPQLMPHTQQPQQQLQQQPQLPPQQAQAPPQTPQQQQQMMMMLMMQQDSKSVRLPVPQGIHPPRGPLNPDAQRMPMQQSGNMPVMVNLQGPGSVPLSPDKQRISLPGNPPLGNNARKMVYQDNVQNPSSSPLGEVSSVSSLPEGGGTEGPPASGAQNNLTSHLVVSQNQLMMTGAKPGPSPLSSTQGASPQQQSNSLPGSLAHHFPNVATPSQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLSRGFDQQGLNPTTLKAIGQAPSNLTINNQSSFAAPQSHKLESVVNSGKQTNAGGTKRASPSNSRRSSPGSSRKTTPSPGRQNSKAAKLSLTTPQNPSLLQNVDMQRNIMVGPASLPTPVTTSFQNNNMLSNQSPSVSAPAMTGIPEDNKESLGVSQDNECQSAQIVQGNKDQPSIELKGIPTPEIKMLVPEEQSKKDGQALDVGKLPVLEESKTMVSPAMREAPTSLSQLLDNSGAPNITIKPPGLTGLEMAPVVTTVEEIKKVAVIPPLQDTSSSKEPSNSLSLPQSNEPCSNPGHQEPGEINSNVTQSVPPVMQRPVTSSISAPLPPNQITVFVTSNPITSSANTSAPLPSHLQPALVSTVVTMPNVGNKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPTAPMTSNSSLMPQSVAVVGPLHIPQNIKFSSAPAPPTTSSSSPAPSIPTSRPLVLNPLAPSVQLPSPATTTSNVPSHLPAQPAKDSSPEEAASQGSGSSDQCPVTATQPGPVVSPLLTSSPGPGNRRSPVSSSKGKGKVDKIGQLLLTKACKKVTGSLEKGEEQYTLDGEAEGQGLETSVPSGLGTEQSPAELDNKTVTPPAPSLTKQSTSGPGNVSISTAAAVSASVSPSLSTSTPPTSALSAVTTPAIPELAPATPSTNGSNHGSLPAEQTGGGLVEDKTGTRQELLQNTASSQHLTQKKSSVATSESTVQRTELETNAPVVAGQSNETKENCEKSKTPSRRNSRTEDSAASQETVENGQRKRSSRPASASSTAKGKMHSRHFCGQGRK", "length": 2053, "header": "tr|A0A8V0ZRM6-1|A0A8V0ZRM6_CHICK Isoform 1 of Nuclear receptor coactivator 6 OS=Gallus gallus OX=9031 GN=NCOA6 PE=4 SV=1 CANONICAL=A0A8V0ZRM6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6/entry#A0A8V0ZDS7-1", "sequence": { "sequence": "MSDWFPLLDTMVLDDLPNLGDTCASLYSLAMEDLEVDLDSGVEEDELKQEVAPEDSTIFVAFKGDIGDRDFEQKLSVILENVPGLLHMESNKLKLQKIEPWNSVRVTFNIPREAAERLRILAQNNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRINGPLGANNSVRMETGFPMQGGQGLIRMSNAAAVMMSQSGSVPSSMVAGGASTELQPRAPRPSSQPDAMDPLLSGLNIQQQNHPSGSLAPQLHSMQSVPVNRQMNSANFQQLQQQTQLQTRPPQPHQQPQQGIRPSFTSPAQVPVPPGWNQLPSGALQPPPTQGALGTLTVNQGWKKAPLPGQMQQQLQARPSLATVQTPTHPPPPYPFGSQQASQAHSNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQSSTLPQGFQQTVSSPSRNPMVQQGNVPPNFMVMQQQNQGPQGLHPGLGGMPKRLPPGFPAGQANQSFMQGQVPSTAPGTPVNSGAPQLQTSQNVQHTGGQGSGPPQNQMQAPHGPPNMMQTNLMGLHGNMNNQQAGASGVPQVNMSNIQGQPQQGPQSQLMGMHQQIVSSQGQMVNIQAQGSMNPQNQMILSRSQLMPQGQMMVTPQSQNLGPSPQRMTPPKQMISQQGQQMMSTHNQMMGPQGQVLLQPNSMMEQMMTTQMQGNKQPFNTQNQSSVMSGPAQLMRGPTPNMQGNMVQFSGQMMAQQGPVNGNPSQVMGIQGQVLRPTGPGPHMSQQLGDTTTATNNDVNMTQMLPDVPVQQSNMVPSHMQAMQGNNSSSGSHFSGHGLPFNSGFSGTPNGNQISCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKPNSQNASKPKKKKPPRKKKTNQQLEQTNSSEPRPGGLEESDQSSTSGDQGINLDNSGPKLSDFGSRPPGYPSQPVEQRPLQQMPPQLMPHTQQPQQQLQQQPQLPPQQAQAPPQTPQQQQQMMMMLMMQQDSKSVRLPVPQGIHPPRGPLNPDAQRMPMQQSGNMPVMVNLQGPGSVPLSPDKQRISLPGNPPLGNNARKMVYQDNVQNPSSSPLGEVSSVSSLPEGGGTEGPPASGAQNNLTSHLVVSQNQLMMTGAKPGPSPLSSTQGASPQQQSNSLPGSLAHHFPNVATPSQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLSRGFDQQGLNPTTLKAIGQAPSNLTINNQSSFAAPQSHKLESVVNSGKQTNAGGTKRASPSNSRRSSPGSSRKTTPSPGRQNSKAAKLSLTTPQNPSLLQNVDMQRNIMVGPASLPTPVTTSFQNNNMLSNQSPSVSAPAMTGIPEDNKESLGVSQDNECQSAQIVQGNKDQPSIELKGIPTPEIKMLVPEEQSKKDGQALDVGKLPVLEESKTMVSPAMREAPTSLSQLLDNSGAPNITIKPPGLTGLEMAPVVTTVEEIKKVAVIPPLQDTSSSKEPSNSLSLPQSNEPCSNPGHQEPGEINSNVTQSVPPVMQRPVTSSISAPLPPNQITVFVTSNPITSSANTSAPLPSHLQPALVSTVVTMPNVGNKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPTAPMTSNSSLMPQSVAVVGPLHIPQNIKFSSAPAPPTTSSSSPAPSIPTSRPLVLNPLAPSVQLPSPATTTSNVPSHLPAQPAKDSSPEEAASQGSGSSDQCPVTATQPGPVVSPLLTSSPGPGNRRSPVSSSKGKGKVDKIGQLLLTKACKKVTGSLEKGEEQYTLDGEAEGQGLETSVPSGLGTEQSPAELDNKTVTPPAPSLTKQSTSGPGNVSISTAAAVSASVSPSLSTSTPPTSALSAVTTPAIPELAPATPSTNGSNHGSLPAEQTGGGLVEDKTGTRQELLQNTASSQHLTQKKSSVATSESTVQRTELETNAPVVAGQSNETKENCEKSKTPSRRNSRTEDSAASQETVENGQRKRSSRPASASSTAKDFLKCDC", "length": 2046, "header": "tr|A0A8V0ZDS7-1|A0A8V0ZRM6_CHICK Computationally mapped isoform of Nuclear receptor coactivator 6 OS=Gallus gallus OX=9031 GN=NCOA6 PE=4 SV=1 CANONICAL=A0A8V0ZRM6-1" }, "locus": { "chromosome": "20", "start_pos": 876243, "end_pos": 840658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052537.1", "url": "https://www.ensembl.org/id/ENSGALT00010052537.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031444.1", "url": "https://www.ensembl.org/id/ENSGALP00010031444.1" } ] } }, { "isoform_ac": "A0A8V0ZKV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6/entry#A0A8V0ZKV6-1", "sequence": { "sequence": "MSDWFPLLDTMVLDDLPNLGDTCASLYSLAMEDLEVDLDSGVEEDELKQEVAPEDSTIFVAFKGDIGDRDFEQKLSVILENVPGLLHMESNKLKLQKIEPWNSVRVTFNIPREAAERLRILAQNNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRINGPLGANNSVRMETGFPMQGGQGLIRMSNAAAVMMSQSGSVPSSMVAGGASTELQPRAPRPSSQPDAMDPLLSGLNIQQQNHPSGSLAPQLHSMQSVPVNRQMNSANFQQLQQQTQLQTRPPQPHQQPQQGIRPSFTSPAQVPVPPGWNQLPSGALQPPPTQGALGTLTVNQGWKKAPLPGQMQQQLQARPSLATVQTPTHPPPPYPFGSQQASQAHSNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQSSTLPQGFQQTVSSPSRNPMVQQGNVPPNFMVMQQQNQGPQGLHPGLGGMPKRLPPGFPAGQANQSFMQGQVPSTAPGTPVNSGAPQLQTSQNVQHTGGQGSGPPQNQMQAPHGPPNMMQTNLMGLHGNMNNQQAGASGVPQVNMSNIQGQPQQGPQSQLMGMHQQIVSSQGQMVNIQAQGSMNPQNQMILSRSQLMPQGQMMVTPQSQNLGPSPQRMTPPKQMISQQGQQMMSTHNQMMGPQGQVLLQPNSMMEQMMTTQMQGNKQPFNTQNQSSVMSGPAQLMRGPTPNMQGNMVQFSGQMMAQQGPVNGNPSQVMGIQGQVLRPTGPGPHMSQQLGDTTTATNNDVNMTQMLPDVPVQQSNMVPSHMQAMQGNNSSSGSHFSGHGLPFNSGFSGTPNGNQISCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKPNSQNASKPKKKKPPRKKKTNQQLEQTNSSEPRPGGLEESDQSSTSGDQGINLDNSGPKLSDFGSRPPGYPSQPVEQRPLQQMPPQLMPHTQQPQQQLQQQPQLPPQQAQAPPQTPQQQQQMMMMLMMQQDSKSVRLPVPQGIHPPRGPLNPDAQRMPMQQSGNMPVMVNLQGPGSVPLSPDKQRISLPGNPPLGNNARKMVYQDNVQNPSSSPLGEVSSVSSLPEGGGTEGPPASGAQNNLTSHLVVSQNQLMMTGAKPGPSPLSSTQGASPQQQSNSLPGSLAHHFPNVATPSQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLSRGFDQQGLNPTTLKAIGQAPSNLTINNQSSFAAPQSHKLESVVNSGKQTNAGGTKRASPSNSRRSSPGSSRKTTPSPGRQNSKAAKLSLTTPQNPSLLQNVDMQRNIMVGPASLPTPVTTSFQNNNMLSNQSPSVSAPAMTGIPEDNKESLGVSQDNECQSAQIVQGNKDQPSIELKGIPTPEIKMLVPEEQSKKDGQALDVGKLPVLEESKTMVSPAMREAPTSLSQLLDNSGAPNITIKPPGLTGLEMAPVVTTVEEIKKVAVIPPLQDTSSSKEPSNSLSLPQSNEPCSNPGHQEPGEINSNVTQSVPPVMQRPVTSSISAPLPPNQITVFVTSNPITSSANTSAPLPSHLQPALVSTVVTMPNVGNKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPTAPMTSNSSLMPQSVAVVGPLHIPQNIKFSSAPAPPTTSSSSPAPSIPTSRPLVLNPLAPSVQLPSPATTTSNVPSHLPAQPAKDSSPEEAASQGSGSSDQCPVTATQPGPVVSPLLTSSPGPGNRRSPVSSSKGKGKVDKIGQLLLTKACKKVTGSLEKGEEQYTLDGEAEGQGLETSVPSGLGTEQSPAELDNKTVTPPAPSLTKQSTSGPGNVSISTAAAVSASVSPSLSTSTPPTSALSAVTTPAIPELAPATPSTNGSNHGSLPAEQTGGGLVEDKTGTRQELLQNTELETNAPVVAGQSNETKENCEKSKTPSRRNSRTEDSAASQETVENGQRKRSSRPASASSTAKETSASAMQSKRRKSK", "length": 2031, "header": "tr|A0A8V0ZKV6-1|A0A8V0ZRM6_CHICK Computationally mapped isoform of Nuclear receptor coactivator 6 OS=Gallus gallus OX=9031 GN=NCOA6 PE=4 SV=1 CANONICAL=A0A8V0ZRM6-1" }, "locus": { "chromosome": "20", "start_pos": 872528, "end_pos": 840658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052526.1", "url": "https://www.ensembl.org/id/ENSGALT00010052526.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031433.1", "url": "https://www.ensembl.org/id/ENSGALP00010031433.1" } ] } }, { "isoform_ac": "A0A8V0ZKW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6/entry#A0A8V0ZKW1-1", "sequence": { "sequence": "MSDWFPLLDTMVLDDLPNLGDTCASLYSLAMEDLEVDLDSGVEEDELKQEVAPEDSTIFVAFKGDIGDRDFEQKLSVILENVPGLLHMESNKLKLQKIEPWNSVRVTFNIPREAAERLRILAQNNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRINGPLGANNSVRMETGFPMQGGQGLIRMSNAAAVMMSQSGSVPSSMVAGGASTELQPRAPRPSSQPDAMDPLLSGLNIQQQNHPSGSLAPQLHSMQSVPVNRQMNSANFQQLQQQTQLQTRPPQPHQQPQQGIRPSFTSPAQVPVPPGWNQLPSGALQPPPTQGALGTLTVNQGWKKAPLPGQMQQQLQARPSLATVQTPTHPPPPYPFGSQQASQAHSNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQSSTLPQGFQQTVSSPSRNPMVQQGNVPPNFMVMQQQNQGPQGLHPGLGGMPKRLPPGFPAGQANQSFMQGQVPSTAPGTPVNSGAPQLQTSQNVQHTGGQGSGPPQNQMQAPHGPPNMMQTNLMGLHGNMNNQQAGASGVPQVNMSNIQGQPQQGPQSQLMGMHQQIVSSQGQMVNIQAQGSMNPQNQMILSRSQLMPQGQMMVTPQSQNLGPSPQRMTPPKQMISQQGQQMMSTHNQMMGPQGQVLLQPNSMMEQMMTTQMQGNKQPFNTQNQSSVMSGPAQLMRGPTPNMQGNMVQFSGQMMAQQGPVNGNPSQVMGIQGQVLRPTGPGPHMSQQLGDTTTATNNDVNMTQMLPDVPVQQSNMVPSHMQAMQGNNSSSGSHFSGHGLPFNSGFSGTPNGNQISCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKPNSQNASKPKKKKPPRKKKTNQQLEQTNSSEPRPGGLEESDQSSTSGDQGINLDNSGPKLSDFGSRPPGYPSQPVEQRPLQQMPPQLMPHTQQPQQQLQQQPQLPPQQAQAPPQTPQQQQQMMMMLMMQQDSKSVRLPVPQGIHPPRGPLNPDAQRMPMQQSGNMPVMVNLQGPGSVPLSPDKQRISLPGNPPLGNNARKMVYQDNVQNPSSSPLGEVSSVSSLPEGGGTEGPPASGAQNNLTSHLVVSQNQLMMTGAKPGPSPLSSTQGASPQQQSNSLPGSLAHHFPNVATPSQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLSRGFDQQGLNPTTLKAIGQAPSNLTINNQSSFAAPQSHKLESVVNSGKQTNAGGTKRASPSNSRRSSPGSSRKTTPSPGRQNSKAAKLSLTTPQNPSLLQNVDMQRNIMVGPASLPTPVTTSFQNNNMLSNQSPSVSAPAMTGIPEDNKESLGVSQDNECQSAQIVQGNKDQPSIELKGIPTPEIKMLVPEEQSKKDGQALDVGKLPVLEESKTMVSPAMREAPTSLSQLLDNSGAPNITIKPPGLTGLEMAPVVTTVEEIKKVAVIPPLQDTSSSKEPSNSLSLPQSNEPCSNPGHQEPGEINSNVTQSVPPVMQRPVTSSISAPLPPNQITVFVTSNPITSSANTSAPLPSHLQPALVSTVVTMPNVGNKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPTAPMTSNSSLMPQSVAVVGPLHIPQNIKFSSAPAPPTTSSSSPAPSIPTSRPLVLNPLAPSVQLPSPATTTSNVPSHLPAQPAKDSSPEEAASQGSGSSDQCPVTATQPGPVVSPLLTSSPGPGNRRSPVSSSKGKGKVDKIGQLLLTKACKKVTGSLEKGEEQYTLDGEAEGQGLETSVPSGLGTEQSPAELDNKTVTPPAPSLTKQSTSGPGNVSISTAAAVSASVSPSLSTSTPPTSALSAVTTPAIPELAPATPSTNGSNHGSLPAEQTGGGLVEDKTGTRQELLQNTVMRQKRIVKSLKLQVEEIQEQRILPLHRKL", "length": 1984, "header": "tr|A0A8V0ZKW1-1|A0A8V0ZRM6_CHICK Computationally mapped isoform of Nuclear receptor coactivator 6 OS=Gallus gallus OX=9031 GN=NCOA6 PE=4 SV=1 CANONICAL=A0A8V0ZRM6-1" }, "locus": { "chromosome": "20", "start_pos": 869574, "end_pos": 840658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052531.1", "url": "https://www.ensembl.org/id/ENSGALT00010052531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031438.1", "url": "https://www.ensembl.org/id/ENSGALP00010031438.1" } ] } }, { "isoform_ac": "A0A8V0ZL30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6/entry#A0A8V0ZL30-1", "sequence": { "sequence": "MSDWFPLLDTMVLDDLPNLGDTCASLYSLAMEDLEVDLDSGVEEDELKQEVAPEDSTIFVAFKGDIGDRDFEQKLSVILENVPGLLHMESNKLKLQKIEPWNSVRVTFNIPREAAERLRILAQNNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRINGPLGANNSVRMETGFPMQGGQGLIRMSNAAAVMMSQSGSVPSSMVAGGASTELQPRAPRPSSQPDAMDPLLSGLNIQQQNHPSGSLAPQLHSMQSVPVNRQMNSANFQQLQQQTQLQTRPPQPHQQPQQGIRPSFTSPAQVPVPPGWNQLPSGALQPPPTQGALGTLTVNQGWKKAPLPGQMQQQLQARPSLATVQTPTHPPPPYPFGSQQASQAHSNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQSSTLPQGFQQTVSSPSRNPMVQQGNVPPNFMVMQQQNQGPQGLHPGLGGMPKRLPPGFPAGQANQSFMQGQVPSTAPGTPVNSGAPQLQTSQNVQHTGGQGSGPPQNQMQAPHGPPNMMQTNLMGLHGNMNNQQAGASGVPQVNMSNIQGQPQQGPQSQLMGMHQQIVSSQGQMVNIQAQGSMNPQNQMILSRSQLMPQGQMMVTPQSQNLGPSPQRMTPPKQMISQQGQQMMSTHNQMMGPQGQVLLQPNSMMEQMMTTQMQGNKQPFNTQNQSSVMSGPAQLMRGPTPNMQGNMVQFSGQMMAQQGPVNGNPSQVMGIQGQVLRPTGPGPHMSQQLGDTTTATNNDVNMTQMLPDVPVQQSNMVPSHMQAMQGNNSSSGSHFSGHGLPFNSGFSGTPNGNQISCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKPNSQNASKPKKKKPPRKKKTNQQLEQTNSSEPRPGGLEESDQSSTSGDQGINLDNSGPKLSDFGSRPPGYPSQPVEQRPLQQMPPQLMPHTQQPQQQLQQQPQLPPQQAQAPPQTPQQQQQMMMMLMMQQDSKSVRLPVPQGIHPPRGPLNPDAQRMPMQQSGNMPVMVNLQGPGSVPLSPDKQRISLPGNPPLGNNARKMVYQDNVQNPSSSPLGEVSSVSSLPEGGGTEGPPASGAQNNLTSHLVVSQNQLMMTGAKPGPSPLSSTQGASPQQQSNSLPGSLAHHFPNVATPSQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLSRGFDQQGLNPTTLKAIGQAPSNLTINNQSSFAAPQSHKLESVVNSGKQTNAGGTKRASPSNSRRSSPGSSRKTTPSPGRQNSKAAKLSLTTPQNPSLLQNVDMQRNIMVGPASLPTPVTTSFQNNNMLSNQSPSVSAPAMTGIPEDNKESLGVSQDNECQSAQIVQGNKDQPSIELKGIPTPEIKMLVPEEQSKKDGQALDVGKLPVLEESKTMVSPAMREAPTSLSQLLDNSGAPNITIKPPGLTGLEMAPVVTTVEEIKKVAVIPPLQDTSSSKEPSNSLSLPQSNEPCSNPGHQEPGEINSNVTQSVPPVMQRPVTSSISAPLPPNQITVFVTSNPITSSANTSAPLPSHLQPALVSTVVTMPNVGNKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPTAPMTSNSSLMPQSVAVVGPLHIPQNIKFSSAPAPPTTSSSSPAPSIPTSRPLVLNPLAPSVQLPSPATTTSNVPSHLPAQPAKDSSPEEAASQGSGSSDQCPVTATQPGPVVSPLLTSSPGPGNRRSPVSSSKGKGKVDKIGQLLLTKACKKVTGSLEKGEEQYTLDGEAEGQGLETSVPSGLGTEQSPAELDNKTVTPPAPSLTKQSTSGPGNVSISTAAAVSASVSPSLSTSTPPTSALSAVTTPAIPELAPATPSTNGSNHGSLPAEQTGGGLVEDKTGTRQELLQNTVHDHTQGKTGRHLRDSIFSTFNAEKKFSCHIRKYCSKNRT", "length": 1994, "header": "tr|A0A8V0ZL30-1|A0A8V0ZRM6_CHICK Computationally mapped isoform of Nuclear receptor coactivator 6 OS=Gallus gallus OX=9031 GN=NCOA6 PE=4 SV=1 CANONICAL=A0A8V0ZRM6-1" }, "locus": { "chromosome": "20", "start_pos": 866810, "end_pos": 840658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052535.1", "url": "https://www.ensembl.org/id/ENSGALT00010052535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031442.1", "url": "https://www.ensembl.org/id/ENSGALP00010031442.1" } ] } }, { "isoform_ac": "A0A8V0ZRM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6/entry#A0A8V0ZRM6-1", "sequence": { "sequence": "MSDWFPLLDTMVLDDLPNLGDTCASLYSLAMEDLEVDLDSGVEEDELKQEVAPEDSTIFVAFKGDIGDRDFEQKLSVILENVPGLLHMESNKLKLQKIEPWNSVRVTFNIPREAAERLRILAQNNNQQLRDLGILSVQIEGEGAINLALAQNRSQDVRINGPLGANNSVRMETGFPMQGGQGLIRMSNAAAVMMSQSGSVPSSMVAGGASTELQPRAPRPSSQPDAMDPLLSGLNIQQQNHPSGSLAPQLHSMQSVPVNRQMNSANFQQLQQQTQLQTRPPQPHQQPQQGIRPSFTSPAQVPVPPGWNQLPSGALQPPPTQGALGTLTVNQGWKKAPLPGQMQQQLQARPSLATVQTPTHPPPPYPFGSQQASQAHSNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQSSTLPQGFQQTVSSPSRNPMVQQGNVPPNFMVMQQQNQGPQGLHPGLGGMPKRLPPGFPAGQANQSFMQGQVPSTAPGTPVNSGAPQLQTSQNVQHTGGQGSGPPQNQMQAPHGPPNMMQTNLMGLHGNMNNQQAGASGVPQVNMSNIQGQPQQGPQSQLMGMHQQIVSSQGQMVNIQAQGSMNPQNQMILSRSQLMPQGQMMVTPQSQNLGPSPQRMTPPKQMISQQGQQMMSTHNQMMGPQGQVLLQPNSMMEQMMTTQMQGNKQPFNTQNQSSVMSGPAQLMRGPTPNMQGNMVQFSGQMMAQQGPVNGNPSQVMGIQGQVLRPTGPGPHMSQQLGDTTTATNNDVNMTQMLPDVPVQQSNMVPSHMQAMQGNNSSSGSHFSGHGLPFNSGFSGTPNGNQISCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKPNSQNASKPKKKKPPRKKKTNQQLEQTNSSEPRPGGLEESDQSSTSGDQGINLDNSGPKLSDFGSRPPGYPSQPVEQRPLQQMPPQLMPHTQQPQQQLQQQPQLPPQQAQAPPQTPQQQQQMMMMLMMQQDSKSVRLPVPQGIHPPRGPLNPDAQRMPMQQSGNMPVMVNLQGPGSVPLSPDKQRISLPGNPPLGNNARKMVYQDNVQNPSSSPLGEVSSVSSLPEGGGTEGPPASGAQNNLTSHLVVSQNQLMMTGAKPGPSPLSSTQGASPQQQSNSLPGSLAHHFPNVATPSQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLSRGFDQQGLNPTTLKAIGQAPSNLTINNQSSFAAPQSHKLESVVNSGKQTNAGGTKRASPSNSRRSSPGSSRKTTPSPGRQNSKAAKLSLTTPQNPSLLQNVDMQRNIMVGPASLPTPVTTSFQNNNMLSNQSPSVSAPAMTGIPEDNKESLGVSQDNECQSAQIVQGNKDQPSIELKGIPTPEIKMLVPEEQSKKDGQALDVGKLPVLEESKTMVSPAMREAPTSLSQLLDNSGAPNITIKPPGLTGLEMAPVVTTVEEIKKVAVIPPLQDTSSSKEPSNSLSLPQSNEPCSNPGHQEPGEINSNVTQSVPPVMQRPVTSSISAPLPPNQITVFVTSNPITSSANTSAPLPSHLQPALVSTVVTMPNVGNKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGSQPSTIPTAPMTSNSSLMPQSVAVVGPLHIPQNIKFSSAPAPPTTSSSSPAPSIPTSRPLVLNPLAPSVQLPSPATTTSNVPSHLPAQPAKDSSPEEAASQGSGSSDQCPVTATQPGPVVSPLLTSSPGPGNRRSPVSSSKGKGKVDKIGQLLLTKACKKVTGSLEKGEEQYTLDGEAEGQGLETSVPSGLGTEQSPAELDNKTVTPPAPSLTKQSTSGPGNVSISTAAAVSASVSPSLSTSTPPTSALSAVTTPAIPELAPATPSTNGSNHGSLPAEQTGGGLVEDKTGTRQELLQNTASSQHLTQKKSSVATSESTVQRTELETNAPVVAGQSNETKENCEKSKTPSRRNSRTEDSAASQETVENGQRKRSSRPASASSTAKGKMHSRHFCGQGRK", "length": 2053, "header": "tr|A0A8V0ZRM6-1|A0A8V0ZRM6_CHICK Isoform 1 of Nuclear receptor coactivator 6 OS=Gallus gallus OX=9031 GN=NCOA6 PE=4 SV=1 CANONICAL=A0A8V0ZRM6-1" }, "locus": { "chromosome": "20", "start_pos": 869675, "end_pos": 840658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052523.1", "url": "https://www.ensembl.org/id/ENSGALT00010052523.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031430.1", "url": "https://www.ensembl.org/id/ENSGALP00010031430.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1184, "start_aa": "Thr", "end_pos": 1184, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1184", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1919, "start_aa": "Thr", "end_pos": 1919, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1919", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 320, "start_aa": "Thr", "end_pos": 320, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr320", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6" } ], "pmid": "" }, { "name": "nuclear thyroid hormone receptor binding", "id": "GO:0046966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6" } ], "pmid": "" }, { "name": "histone methyltransferase complex", "id": "GO:0035097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035097", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6" } ], "pmid": "" }, { "name": "DNA-templated transcription initiation", "id": "GO:0006352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006352", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6" } ], "pmid": "" }, { "name": "myeloid cell differentiation", "id": "GO:0030099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030099", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1132, "end_pos": 1134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1227, "end_pos": 1229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1247, "end_pos": 1249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1271, "end_pos": 1273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1276, "end_pos": 1278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1379, "end_pos": 1381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1486, "end_pos": 1488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1554, "end_pos": 1556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1594, "end_pos": 1596, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1645, "end_pos": 1647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1669, "end_pos": 1671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1857, "end_pos": 1859, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"https://www.ensembl.org/id/ENSGALG00010021953" } ] } } ], "crossref": [ { "id": "A0A8V0ZNA7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNA7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08889", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08889", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031315", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF02121", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02121", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24694", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24694", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24695", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24695", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1483226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1483226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZFU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZFU1-1", "url": 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"MLIKEYHILLPMSLEEYQKKSREESSGEGSGVEILANRPYSDGPGGSGQYTHKIYHVGSHIPSWFRALLPKAALQVEEESWNAYPYTRTRYTCPFVEKFSIEIETYYRPDAGQQTNIFNLSAAEKRQRILDTIDIVRDPISPGEYKPEEDPKLYRSAKTGRGPLGDNWLEAASSGPLMCAYKLCKVEFRYWGMQSKIEQFIHDVGLRKVMLRAHRQAWCWQDEWTDLTMEDIRQLEEETARMLAQKMAKCGEAEEPSTAGPSPEGRPEPGGASGQEGSEAQGAADISPDDSFAKQWSTSSRSSYSSQHGGGVSPQSLSEWRMQNIARDSENSSEEEFFDAHEDLSDSDEVFAKEMTKWSSNDFLDTLERPAELDDNLGEGPSASRTDGKEQPASSFSEGGSAESTVQACRIHVLFLILHSGNILDQGGGELGSKQADVQTLAATFDAVTRVHFPEALGHVALRLVPCPPICAAAYALVSKLSPYSHDRDSLSSSQDHIPLAALPLLATSSGSYQHAVGNVITRANQAYAAFLHSAEGTGFCGQVVLLGDCVGGILGFDALCQSRAGAGGSRSSSRRGSLSTEPISPELCGTRDPLAEGADAAVGLGQASPEPGDSQHPGSSCSPQPGDAPLEAEAPRNSAAAQDGAESTSTRLDFKVSGFFLFGSPLGLVLALRKTVMPALDVAQLRPACEQIYNLFHAADPCASRLEPLLAKAFHAVPPLSVPRYQKYPLGDGTSSLLAEALQMHSALFLPEVDLAAPPTPTGSFGGGFWRGSEPGDPPTPASTSEVVKILERWWGLKRIDYSLYCPDALTAFPTITLPHLFHASYWESSDVVAFILRQVMEKEGPQPAESEESSIYSPAFPREKWQRKRTQVKIRNVTANHRASDVIVCEGKAQVLSGRFMYGPLDVVTLTGEKVDIYIMTQPLSGKWLYYGTEVTSGSGRLTFTIPQDKALAIGIYPVRMVVRGDHSYAEAYLTVVARGTESVVFSIDGSFTASVSIMGSDPKVRAGAVDVVRHWQDSGYMIIYVTGRPDMQKHRVVAWLSQHNFPHGAVSFCDGLTHDPLRQKAAFLQSLRAEAEIAIVAGYGSTKDVSVYSSLGLAPAHIYIVGRAVKKFHNQCQFLSEGYVAHLAQLEAAALVHSPKGPPRPVLGKGTYGCPAPVDFLRKQSQLLRSRGSSQAERDGGPLPARAKPRSVSLKLEGEE", 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"length": 1130, "header": "tr|A0A8V0ZFU1-1|A0A8V0ZNA7_CHICK Computationally mapped isoform of Phosphatidylinositol transfer protein membrane associated 1 OS=Gallus gallus OX=9031 GN=PITPNM1 PE=3 SV=1 CANONICAL=A0A8V0ZNA7-1" }, "locus": { "chromosome": "5", "start_pos": 617577, "end_pos": 609631, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053377.1", "url": "https://www.ensembl.org/id/ENSGALT00010053377.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032175.1", "url": "https://www.ensembl.org/id/ENSGALP00010032175.1" } ] } }, { "isoform_ac": "A0A8V0ZNA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA7/entry#A0A8V0ZNA7-1", "sequence": { "sequence": 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"url": "https://www.ensembl.org/id/ENSGALP00010032342.1" } ] } }, { "isoform_ac": "A0A8V0ZND8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8/entry#A0A8V0ZND8-1", "sequence": { "sequence": "MAALPGETTPGARQGEAGAGPLPSPAGRPLRALRKATAALPRALPSGAPARPRWGWRRLWAPGQRGCFSTRRCCTRRCGRSCPPPAGRGSTASTAPCCWERCRCGAAALVAEENVRAVLTLNEEYETRFLCCSAQEWEALGVEQLRLGTVDLTGVPTLDNLHRGVEFILKHRERGNSVYVHCKAGRSRSATVVAAYLIQLHHWSPQEAIEAIAKIRPHILIRRKQVQVLESFHRDVTAGTTAKCQ", "length": 245, "header": "tr|A0A8V0ZND8-1|A0A8V0ZND8_CHICK Isoform 1 of Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 OS=Gallus gallus OX=9031 GN=PTPMT1 PE=3 SV=1 CANONICAL=A0A8V0ZND8-1" }, "locus": { "chromosome": "5", "start_pos": 22336120, "end_pos": 22334026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053681.1", "url": "https://www.ensembl.org/id/ENSGALT00010053681.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032335.1", "url": "https://www.ensembl.org/id/ENSGALP00010032335.1" } ] } }, { "isoform_ac": "A0A8V0ZNQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8/entry#A0A8V0ZNQ9-1", "sequence": { "sequence": "MGVAAALGAGAARLLFYPTLLYTALRAQLPASRRPWFHRIDRAVLLGALPLRGRSRRLVAEENVRAVLTLNEEYETRFLCCSAQLHHWSPQEAIEAIAKIRPHILIRRKQVQVLESFHRDVTAGTTAKCQ", "length": 130, "header": "tr|A0A8V0ZNQ9-1|A0A8V0ZNQ9_CHICK Computationally mapped isoform of Protein tyrosine phosphatase, mitochondrial 1 OS=Gallus gallus OX=9031 GN=PTPMT1 PE=1 SV=1 CANONICAL=A0A8V0ZND8-1" }, "locus": { "chromosome": "5", "start_pos": 22335962, "end_pos": 22334026, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053664.1", "url": "https://www.ensembl.org/id/ENSGALT00010053664.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032324.1", "url": "https://www.ensembl.org/id/ENSGALP00010032324.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" }, { "name": "phosphatidylglycerophosphatase activity", "id": "GO:0008962", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008962", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" }, { "name": "phosphatidylinositol-5-phosphate phosphatase activity", "id": "GO:0102091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" }, { "name": "regulation of intrinsic apoptotic signaling pathway", "id": "GO:2001242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" }, { "name": "mitochondrial fragmentation involved in apoptotic process", "id": "GO:0043653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043653", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" }, { "name": "cardiolipin biosynthetic process", "id": "GO:0032049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZND8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1AB34-1", "A0A1D5PI23-1", "A0A8V0ZW37-1", "P62207-1", "F1P225-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "A0A1D5PJC6-1", "A0A8V0XTW9-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZFN2-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V1A8D0-1", "E1BTX9-1", "E1BRQ8-1", "A0A8V0ZJ28-1", "A0A8V0XYX4-1", "A0A8V0ZE41-1", "A0A8V0X9H5-1", "E1BYA9-1", "A0A8V0ZXB3-1", "F1NXH3-1", "A0A1D5P5S2-1", "F1NC58-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "A0A8V0XYE1-1", "F1NJB8-1", "Q5F3Z7-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "33751", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZND8-1" ], "evidence": [ { "id": "33751", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/33751" } ] }, { "id": "42304", "name": "", "equation": "1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol-3'-phosphate) + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZND8-1" ], "evidence": [ { "id": "42304", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42304" } ] }, { "id": "42308", "name": "", "equation": "1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZND8-1" ], "evidence": [ { "id": "42308", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42308" } ] }, { "id": "42320", "name": "", "equation": "a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O = a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZND8-1" ], "evidence": [ { "id": "42320", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42320" } ] }, { "id": "42584", "name": "", "equation": "1,2-dibutyryl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O = 1,2-dibutyryl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZND8-1" ], "evidence": [ { "id": "42584", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42584" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y3H9-1", "A0A1D5PI23-1", "P62207-1", "A0A8V0ZIN0-1", "F1P225-1", "E1BVM8-1", "A0A8V1ANF4-1", "A0A1D5P5S2-1", "P0C597-1", "P48463-1", "Q9PTJ6-1", "Q9PW71-1", "A0A8V0Z2T2-1", "A0A8V0ZYK3-1", "Q5ZJJ8-1", "Q5ZJQ7-1", "Q9YHA0-1", "F1NCC5-1", "A0A1D5PJC6-1", "E1BTX9-1", "A0A8V0XTW9-1", "A0A8V0XYX4-1", "A0A8V0XLK8-1", "A0A8V0Y1D0-1", "A0A8V0Z256-1", "A0A8V0ZE41-1", "A0A8V0ZMU4-1", "A0A8V0ZMX1-1", "A0A8V0ZQ53-1", "A0A8V0ZPJ8-1", "A0A8V0ZWA8-1", "A0A8V0ZU36-1", "E1BRQ8-1", "A0A8V1A8D0-1", "A0A8V0ZJ28-1", "A0A8V0X9H5-1", "A0A8V1AB34-1", "E1BYA9-1", "A0A8V0ZXB3-1", "A0A8V0ZFN2-1", "F1NXH3-1", "A0A8V0ZW37-1", "A0A8V0ZA69-1", "A0A8V1A6D3-1", "F1N842-1", "A0A8V0YC26-1", "A0A8V0XYE1-1", "F1NJB8-1", "A0A8V0ZND8-1", "A0A8V0ZS02-1", "A0A8V1AKZ7-1", "A0A8V1AK42-1", "Q5F3Z7-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P5S2", "gene_name": "DUSP5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5P5S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P5S2" } ] } ] }, { "uniprot_ac": "A0A1D5PI23", "gene_name": "DUSP3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PI23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PI23" } ] } ] }, { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A8V0X9H5", "gene_name": "PPM1L", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0X9H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9H5" } ] } ] }, { "uniprot_ac": "A0A8V0XLK8", "gene_name": "PPEF2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XLK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLK8" } ] } ] }, { "uniprot_ac": "A0A8V0XTW9", "gene_name": "PPP3CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XTW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XTW9" } ] } ] }, { "uniprot_ac": "A0A8V0XYE1", "gene_name": "PHLPP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYE1" } ] } ] }, { "uniprot_ac": "A0A8V0XYX4", "gene_name": "DUSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0XYX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XYX4" } ] } ] }, { "uniprot_ac": "A0A8V0Y1D0", "gene_name": "CTDP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y1D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1D0" } ] } ] }, { "uniprot_ac": "A0A8V0Y3H9", "gene_name": "PPP2CB", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Y3H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3H9" } ] } ] }, { "uniprot_ac": "A0A8V0YC26", "gene_name": "DUSP19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0YC26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YC26" } ] } ] }, { "uniprot_ac": "A0A8V0Z256", "gene_name": "CDKN3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z256" } ] } ] }, { "uniprot_ac": "A0A8V0Z2T2", "gene_name": "DUSP26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0Z2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T2" } ] } ] }, { "uniprot_ac": "A0A8V0ZA69", "gene_name": "PGAM5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZA69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA69" } ] } ] }, { "uniprot_ac": "A0A8V0ZE41", "gene_name": "PPM1B", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZE41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZE41" } ] } ] }, { "uniprot_ac": "A0A8V0ZFN2", "gene_name": "CTDSP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFN2" } ] } ] }, { "uniprot_ac": "A0A8V0ZIN0", "gene_name": "SSH1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZIN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIN0" } ] } ] }, { "uniprot_ac": "A0A8V0ZJ28", "gene_name": "PTEN", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZJ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJ28" } ] } ] }, { "uniprot_ac": "A0A8V0ZMU4", "gene_name": "DUSP13", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZMU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMU4" } ] } ] }, { "uniprot_ac": "A0A8V0ZMX1", "gene_name": "RPAP2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZND8", "gene_name": "PTPMT1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" } ] } ] }, { "uniprot_ac": "A0A8V0ZPJ8", "gene_name": "LOC100857573", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZPJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ8" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ53", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ53" } ] } ] }, { "uniprot_ac": "A0A8V0ZS02", "gene_name": "PPM1F", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZS02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS02" } ] } ] }, { "uniprot_ac": "A0A8V0ZU36", "gene_name": "SSH3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZU36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU36" } ] } ] }, { "uniprot_ac": "A0A8V0ZW37", "gene_name": "CDC14A", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW37" } ] } ] }, { "uniprot_ac": "A0A8V0ZWA8", "gene_name": "PPP1CA", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZWA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWA8" } ] } ] }, { "uniprot_ac": "A0A8V0ZXB3", "gene_name": "DUSP28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8V0ZXB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXB3" } ] } ] }, { "uniprot_ac": "A0A8V0ZYK3", "gene_name": "PPP1CC", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V0ZYK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYK3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": 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"A0A8V1A8D0", "gene_name": "PPTC7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1A8D0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8D0" } ] } ] }, { "uniprot_ac": "A0A8V1AB34", "gene_name": "CTDSPL", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AB34" } ] } ] }, { "uniprot_ac": "A0A8V1AK42", "gene_name": "DUSP23", "activity": [ { 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"id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1AKZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKZ7" } ] } ] }, { "uniprot_ac": "A0A8V1ANF4", "gene_name": "SSH2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8V1ANF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANF4" } ] } ] }, { "uniprot_ac": "E1BRQ8", "gene_name": "DUSP15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "E1BRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRQ8" } ] } ] }, { "uniprot_ac": "E1BTX9", "gene_name": "PPEF1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BTX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BTX9" } ] } ] }, { "uniprot_ac": "E1BVM8", "gene_name": "PPM1A", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BVM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BVM8" } ] } ] }, { "uniprot_ac": "E1BYA9", "gene_name": "ILKAP", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "E1BYA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYA9" } ] } ] }, { "uniprot_ac": "F1N842", "gene_name": "DUSP12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1N842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N842" } ] } ] }, { "uniprot_ac": "F1NC58", "gene_name": "PDXP", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NC58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NC58" } ] } ] }, { "uniprot_ac": "F1NCC5", "gene_name": "DUSP4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NCC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCC5" } ] } ] }, { "uniprot_ac": "F1NJB8", "gene_name": "PHLPP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NJB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJB8" } ] } ] }, { "uniprot_ac": "F1NXH3", "gene_name": "DUSP10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1NXH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NXH3" } ] } ] }, { "uniprot_ac": "F1P225", "gene_name": "LOC423731", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "F1P225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P225" } ] } ] }, { "uniprot_ac": "P0C597", "gene_name": "DUSP29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "P0C597", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P0C597" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + 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phosphate.", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.53", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "P62207", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P62207" } ] } ] }, { "uniprot_ac": "Q5F3Z7", "gene_name": "CTDSPL2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5F3Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3Z7" } ] } ] }, { "uniprot_ac": "Q5ZJJ8", "gene_name": "UBLCP1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJJ8" } ] } ] }, { "uniprot_ac": "Q5ZJQ7", "gene_name": "SSU72", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q5ZJQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZJQ7" } ] } ] }, { "uniprot_ac": "Q9PTJ6", "gene_name": "NFI1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": 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"Q9PW71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9PW71" } ] } ] }, { "uniprot_ac": "Q9YHA0", "gene_name": "EYA1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "Q9YHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9YHA0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 159, "end_pos": 227, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZND8" }, { "id": "PS50054", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50054" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 89, "end_pos": 238, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.16", "ec_name": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.16", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.16" }, { "id": "3.1.3.16", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.16" } ] }, { "ec_number": "3.1.3.27", "ec_name": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "3.1.3.27", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.27" }, { "id": "3.1.3.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNH6-1", "uniprot_ac": "A0A8V0ZNH6", "uniprot_id": "A0A8V0ZNH6_CHICK", "mass": { "chemical_mass": 230658.0, "monoisotopic_mass": 230658.0 }, "refseq": { "ac": "XP_015143778", "name": "disks large homolog 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143778" }, "gene_names": [ { "name": "DLG5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ] }, { "name": "DLG5", "type": "synonym", "evidence": [ { "id": "XP_015143778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143778" } ] } ], "protein_names": [ { "name": "Discs large MAGUK scaffold protein 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6/entry#names_and_taxonomy" } ] }, { "name": "disks large homolog 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015143778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143778" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015143778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143778" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DLG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6", "locus": { "chromosome": "6", "start_pos": 14077749, "end_pos": 13982816, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022105", "url": "https://www.ensembl.org/id/ENSGALG00010022105" } ] } } ], "crossref": [ { "id": "cd06764", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06764", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06766", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06766", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11860", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11860", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423728", "url": "https://www.ncbi.nlm.nih.gov/gene/423728", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035537", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035537", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423728", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423728", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZGC8", "url": "https://www.orthodb.org/?gene=A0A8V0ZGC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLQ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZLQ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNH6", "url": "https://www.orthodb.org/?gene=A0A8V0ZNH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46360:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46360:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013420", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013424", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696264", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015143778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015143778", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZGC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPKHKELLAQCRQSLAQAMTEVDKVVELLEAAGALGPRDLRDLEAAGGGKAELLIALLLAKERDHFQDLRVALEKTQPHLLSILYLNGVAGAPAAAEETAGSTYSVLSIMPSDSESSSSLSSIGTTGKASSPPPVADTRQMSEKLETILFQLRQVTRERDELRKRLALSSPGSTFDDCRPSPKPNHDYERLKIQCMKAMSDLQSLQNQHTKTLKRCEEAAKEADFYHTLHSRLLSDQSQLKEDMDTLKRKNTQLVREHNHLQQSCEEMKRLHDEDQKEITDLRSQQQQVMKQNGSSEILNKLYDTAMDKLEGVKKDYDALRKRYNEKIASHNTDLSRLEQAEEENRRLQKQIDMLMKQRDTAIHFQQQYSSSLRRFESVQQELSNATAQNKELQREMERLQSEVTRFKTMQLKAAKDSEKYKEERDSVFNEYRLIMSERDQVIKEVDKLQTELELAESKLKNTSSEKRVASEEMEALRQELNSALVERDRAICERNELLEKYCHEVKDKAEAQKELDQACKDIETVKEERDVARKERTEAIIQRDHLLREYYQARQIQDSATLDIERANKEIEMLRKQYEAMSQELKEAVQEAEVAKCRRDWAFQERDKIVAERESIRTLCDNLRRERDRAVSDLAEALRNLDDMRKQKNDAMRELKELKEKMENQLEKEARFRQLMAHSSHDSAIDTDSLEWETEVVEFEKDRDDMDLKALGFDVAEGVNEPYLPGDCGIFVTKVDKGSIVDGRLRVNDWLLKINDVDLTNKDKKQVIKAVLNGGGVINMVVRRRKSLGGRVITPLHINVSGHKDSGVSLENGIFVAAVVPGSPAAKEGSLTVGDRIIAINGIALDNKSLNECEALLRNCRDSLTLSLLKVFPQSSSWSGQNIFENLKDSEKISNCRVHASEIQAQNKRNMKLNSSTQTDIFNPDIMDVKKDQSDQGSRSFCDHKPFPNNTLRVDSHRNTVHSCHSNSEHSLSSFNPETYGDRGYGVVDLDNRRLPYEPTENDCMVVETAFDKGHGTKHSGGTWPKVMVNISATETEKFSVYKKPKQRKSIFDPDTFKRPPTPPKLEYLSPNQVTGHSPQPSKAEVASTPPTPPKRSDSIKFKHKQQASSASESTVTTGSPPTSPATAQAPVSLALKQDSATLKGRSRNAGNYYREEGIDCTHLSSRKSCEDDIGFQRVEEPEIKRPRPKSAPALRHKMTPMPIPNPALQVQKYTPASEEHLSPELQEWAPYSPKRSARHSDGFVSSTLYTGGMSSGTVPRSLAPCPAVTAVMRNPIYTAWSHRVHTNNCPSVASQICHQHLHPSAQHQGRLSLDLSHKHSNEYSENPRTRASHGSNSLPSSARLGSSSNLQYRTERIKIPLTPRYPRSVMGSDRGSLSHSECSSPSLITPPQSPLNLETSSFASSQSQNSLSTLPRISISPVSAGERRKDRYLFRNRSFLRIPVAPRPRFSSLRSLRPYMEEPRHVKVQKGSEPLGISIVSGENGGIFVSKVTGGSIAHQAGLEYGDQLLEFNGINLRNATEQQARLIIGQQCDTITILAQYNPHMYQLGNHSRSSSRLEPVSNHSTPQGSGAATPDNHSIIDTVSEQDEGTMTPPSKQTTPTTSPRNSLRGPVDTNKRTPEPRTVVVKKSQVDLGIQICGGNLYGIFVSDVDDDSPAKGPDGLVLGDMILEYGSIDMRTKTAEEAYLEMLKPGENIKIKTQYRIEEFNRIKELPGDGFFIRALYDRVAEVEQDLSFKKDDILYVDDTLPQGNFGCWMAWQLDENAQKLERGQIPSKYMMDQEFYRRHSMSETKDENSSSKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDTISTDSIPFLDDSASLAYQRVQKVDCTSPRPVLILGPLLDAVKDMLVKESPGKFCRCPLEVMKASQQAIERGVKDCLFIDYKRRSGHFDVTTVASIKEITEKDCHCLLDIAPHAIERLHSVHIYPIVIFIRYKNAKQIKEQKDPIFLRDKVTQKHSKEQFETAQKIEQEYSKYFTGIVQGGALSSICTQIMTTVDQEQNKVLWIPAGPL", "length": 2045, "header": "tr|A0A8V0ZNH6-1|A0A8V0ZNH6_CHICK Isoform 1 of Discs large MAGUK scaffold protein 5 OS=Gallus gallus OX=9031 GN=DLG5 PE=4 SV=1 CANONICAL=A0A8V0ZNH6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZGC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6/entry#A0A8V0ZGC8-1", "sequence": { "sequence": "MSWKRAEAEMSYCKVSLKGSTYSVLSIMPSDSESSSSLSSIGTTGKASSPPPVADTRQMSEKLETILFQLRQVTRERDELRKRLALSSPGSTFDDCRPSPKPNHDYERLKIQCMKAMSDLQSLQNQHTKTLKRCEEAAKEADFYHTLHSRLLSDQSQLKEDMDTLKRKNTQLVREHNHLQQSCEEMKRLHDEDQKEITDLRSQQQQVMKQNGSSEILNKLYDTAMDKLEGVKKDYDALRKRYNEKIASHNTDLSRLEQAEEENRRLQKQIDMLMKQRDTAIHFQQQYSSSLRRFESVQQELSNATAQNKELQREMERLQSEVTRFKTMQLKAAKDSEKYKEERDSVFNEYRLIMSERDQVIKEVDKLQTELELAESKLKNTSSEKRVASEEMEALRQELNSALVERDRAICERNELLEKYCHEVKDKAEAQKELDQACKDIETVKEERDVARKERTEAIIQRDHLLREYYQARQIQDSATLDIERANKEIEMLRKQYEAMSQELKEAVQEAEVAKCRRDWAFQERDKIVAERESIRTLCDNLRRERDRAVSDLAEALRNLDDMRKQKNDAMRELKELKEKMENQLEKEARFRQLMAHSSHDSAIDTDSLEWETEVVEFEKDRDDMDLKALGFDVAEGVNEPYLPGDCGIFVTKVDKGSIVDGRLRVNDWLLKINDVDLTNKDKKQVIKAVLNGGGVINMVVRRRKSLGGRVITPLHINVSGHKDSGVSLENGIFVAAVVPGSPAAKEGSLTVGDRIIAINGIALDNKSLNECEALLRNCRDSLTLSLLKVFPQSSSWSGQNIFENLKDSEKISNCRVHASEIQAQNKRNMKLNSSTQTDIFNPDIMDVKKDQSDQGSRSFCDHKPFPNNTLRVDSHRNTVHSCHSNSEHSLSSFNPETYGDRGYGVVDLDNRRLPYEPTENDCMVVETAFDKGHGTKHSGGTWPKVMVNISATETEKFSVYKKPKQRKSIFDPDTFKRPPTPPKLEYLSPNQVTGHSPQPSKAEVASTPPTPPKRSDSIKFKHKQQASSASESTVTTGSPPTSPATAQAPVSLALKQDSATLKGRSRNAGNYYREEGIDCTHLSSRKSCEDDIGFQRVEEPEIKRPRPKSAPALRHKMTPMPIPNPALQVQKYTPASEEHLSPELQEWAPYSPKRSARHSDGFVSSTLYTGGMSSGTVPRSLAPCPAVTAVMRNPIYTAWSHRVHTNNCPSVASQICHQHLHPSAQHQGRLSLDLSHKHSNEYSENPRTRASHGSNSLPSSARLGSSSNLQYRTERIKIPLTPRYPRSVMGSDRGSLSHSECSSPSLITPPQSPLNLETSSFASSQSQNSLSTLPRISISPVSAGERRKDRPYMEEPRHVKVQKGSEPLGISIVSGENGGIFVSKVTGGSIAHQAGLEYGDQLLEFNGINLRNATEQQARLIIGQQCDTITILAQYNPHMYQLGNHSRSSSRLEPVSNHSTPQGSGAATPDNHSIIDTVSEQDEGTMTPPSKQTTPTTSPRNSLRGPVDTNKRTPEPRTVVVKKSQVDLGIQICGGNLYGIFVSDVDDDSPAKGPDGLVLGDMILEYGSIDMRTKTAEEAYLEMLKPGENIKIKTQYRIEEFNRIKELPGDGFFIRALYDRVAEVEQDLSFKKDDILYVDDTLPQGNFGCWMAWQLDENAQKLERGQIPSKYMMDQEFYRRHSMSETKDENSSSKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDTISTDSIPFLDDSASLAYQRVQKVDCTSPRPVLILGPLLDAVKDMLVKESPGKFCRCPLEVMKASQQAIERGVKDCLFIDYKRRSGHFDVTTVASIKEITEKDCHCLLDIAPHAIERLHSVHIYPIVIFIRYKNAKQIKEQKDPIFLRDKVTQKHSKEQFETAQKIEQEYSKYFTGIVQGGALSSICTQIMTTVDQEQNKVLWIPAGPL", "length": 1936, "header": "tr|A0A8V0ZGC8-1|A0A8V0ZNH6_CHICK Computationally mapped isoform of Discs large MAGUK scaffold protein 5 OS=Gallus gallus OX=9031 GN=DLG5 PE=4 SV=1 CANONICAL=A0A8V0ZNH6-1" }, "locus": { "chromosome": "6", "start_pos": 14075989, "end_pos": 14000460, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053755.1", "url": "https://www.ensembl.org/id/ENSGALT00010053755.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032367.1", "url": "https://www.ensembl.org/id/ENSGALP00010032367.1" } ] } }, { "isoform_ac": "A0A8V0ZLQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6/entry#A0A8V0ZLQ1-1", "sequence": { "sequence": "MEPKHKELLAQCRQSLAQAMTEVDKVVELLEAAGALGPRDLRDLEAAGGGKAELLIALLLAKERDHFQDLRVALEKTQPHLLSILYLNGVAGAPAAAEETAGSTYSVLSIMPSDSESSSSLSSIGTTGKASSPPPVADTRQMSEKLETILFQLRQVTRERDELRKRLALSSPGSTFDDCRPSPKPNHDYERLKIQCMKAMSDLQSLQNQHTKTLKRCEEAAKEADFYHTLHSRLLSDQSQLKEDMDTLKRKNTQLVREHNHLQQSCEEMKRLHDEDQKEITDLRSQQQQVMKQNGSSEILNKLYDTAMDKLEGVKKDYDALRKRYNEKIASHNTDLSRLEQAEEENRRLQKQIDMLMKQRDTAIHFQQQYSSSLRRFESVQQELSNATAQNKELQREMERLQSEVTRFKTMQLKAAKDSEKYKEERDSVFNEYRLIMSERDQVIKEVDKLQTELELAESKLKNTSSEKRVASEEMEALRQELNSALVERDRAICERNELLEKYCHEVKDKAEAQKELDQACKDIETVKEERDVARKERTEAIIQRDHLLREYYQARQIQDSATLDIERANKEIEMLRKQYEAMSQELKEAVQEAEVAKCRRDWAFQERDKIVAERESIRTLCDNLRRERDRAVSDLAEALRNLDDMRKQKNDAMRELKELKEKMENQLEKEARFRQLMAHSSHDSAIDTDSLEWETEVVEFEKDRDDMDLKALGFDVAEGVNEPYLPGDCGIFVTKVDKGSIVDGRLRVNDWLLKINDVDLTNKDKKQVIKAVLNGGGVINMVVRRRKSLGGRVITPLHINVSGHKDSGVSLENGIFVAAVVPGSPAAKEGSLTVGDRIIAINGIALDNKSLNECEALLRNCRDSLTLSLLKVFPQSSSWSGQNIFENLKDSEKISNCRVHASEIQAQNKRNMKLNSSTQTDIFNPDIMDVKKDQSDQGSRSFCDHKPFPNNTLRVDSHRNTVHSCHSNSEHSLSSFNPETYGDRGYGVVDLDNRRLPYEPTENDCMVVETAFDKGHGTKHSGGTWPKVMVNISATETEKFSVYKKPKQRKSIFDPDTFKRPPTPPKLEYLSPNQVTGHSPQPSKAEVASTPPTPPKRSDSIKFKHKQQASSASESTVTTGSPPTSPATAQAPVSLALKQDSATLKGRSRNAGNYYREEGIDCTHLSSRKSCEDDIGFQRVEEPEIKRPRPKSAPALRHKMTPMPIPNPALQVQKYTPASEEHLSPELQEWAPYSPKRSARHSDGFVSSTLYTGGMSSGTVPRSLAPCPAVTAVMRNPIYTAWSHRVHTNNCPSVASQICHQHLHPSAQHQGRLSLDLSHKHSNEYSENPRTRASHGSNSLPSSARLGSSSNLQYRTERIKIPLTPRYPRSVMGSDRGSLSHSECSSPSLITPPQSPLNLETSSFASSQSQNSLSTLPRISISPVSAGERRKDRPYMEEPRHVKVQKGSEPLGISIVSGENGGIFVSKVTGGSIAHQAGLEYGDQLLEFNGINLRNATEQQARLIIGQQCDTITILAQYNPHMYQLGNHSRSSSRLEPVSNHSTPQGSGAATPDNHSIIDTVSEQDEGTMTPPSKQTTPTTSPRNSLRGPVDTNKRTPEPRTVVVKKSQVDLGIQICGGNLYGIFVSDVDDDSPAKGPDGLVLGDMILEYGSIDMRTKTAEEAYLEMLKPGENIKIKTQYRIEEFNRIKELPGDGFFIRALYDRVAEVEQDLSFKKDDILYVDDTLPQGNFGCWMAWQLDENAQKLERGQIPSKYMMDQEFYRRHSMSETKDENSSSKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDTISTDSIPFLDDSASLAYQRVQKVDCTSPRPVLILGPLLDAVKDMLVKESPGKFCRCPLEVMKASQQAIERGVKDCLFIDYKRRSGHFDVTTVASIKEITEKDCHCLLDIAPHAIERLHSVHIYPIVIFIRYKNAKQIKEQKDPIFLRDKVTQKHSKEQFETAQKIEQEYSKYFTGIVQGGALSSICTQIMTTVDQEQNKVLWIPAGPL", "length": 2019, "header": "tr|A0A8V0ZLQ1-1|A0A8V0ZNH6_CHICK Computationally mapped isoform of Discs large MAGUK scaffold protein 5 OS=Gallus gallus OX=9031 GN=DLG5 PE=4 SV=1 CANONICAL=A0A8V0ZNH6-1" }, "locus": { "chromosome": "6", "start_pos": 14075989, "end_pos": 13983015, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053768.1", "url": "https://www.ensembl.org/id/ENSGALT00010053768.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032374.1", "url": "https://www.ensembl.org/id/ENSGALP00010032374.1" } ] } }, { "isoform_ac": "A0A8V0ZNH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6/entry#A0A8V0ZNH6-1", "sequence": { "sequence": "MEPKHKELLAQCRQSLAQAMTEVDKVVELLEAAGALGPRDLRDLEAAGGGKAELLIALLLAKERDHFQDLRVALEKTQPHLLSILYLNGVAGAPAAAEETAGSTYSVLSIMPSDSESSSSLSSIGTTGKASSPPPVADTRQMSEKLETILFQLRQVTRERDELRKRLALSSPGSTFDDCRPSPKPNHDYERLKIQCMKAMSDLQSLQNQHTKTLKRCEEAAKEADFYHTLHSRLLSDQSQLKEDMDTLKRKNTQLVREHNHLQQSCEEMKRLHDEDQKEITDLRSQQQQVMKQNGSSEILNKLYDTAMDKLEGVKKDYDALRKRYNEKIASHNTDLSRLEQAEEENRRLQKQIDMLMKQRDTAIHFQQQYSSSLRRFESVQQELSNATAQNKELQREMERLQSEVTRFKTMQLKAAKDSEKYKEERDSVFNEYRLIMSERDQVIKEVDKLQTELELAESKLKNTSSEKRVASEEMEALRQELNSALVERDRAICERNELLEKYCHEVKDKAEAQKELDQACKDIETVKEERDVARKERTEAIIQRDHLLREYYQARQIQDSATLDIERANKEIEMLRKQYEAMSQELKEAVQEAEVAKCRRDWAFQERDKIVAERESIRTLCDNLRRERDRAVSDLAEALRNLDDMRKQKNDAMRELKELKEKMENQLEKEARFRQLMAHSSHDSAIDTDSLEWETEVVEFEKDRDDMDLKALGFDVAEGVNEPYLPGDCGIFVTKVDKGSIVDGRLRVNDWLLKINDVDLTNKDKKQVIKAVLNGGGVINMVVRRRKSLGGRVITPLHINVSGHKDSGVSLENGIFVAAVVPGSPAAKEGSLTVGDRIIAINGIALDNKSLNECEALLRNCRDSLTLSLLKVFPQSSSWSGQNIFENLKDSEKISNCRVHASEIQAQNKRNMKLNSSTQTDIFNPDIMDVKKDQSDQGSRSFCDHKPFPNNTLRVDSHRNTVHSCHSNSEHSLSSFNPETYGDRGYGVVDLDNRRLPYEPTENDCMVVETAFDKGHGTKHSGGTWPKVMVNISATETEKFSVYKKPKQRKSIFDPDTFKRPPTPPKLEYLSPNQVTGHSPQPSKAEVASTPPTPPKRSDSIKFKHKQQASSASESTVTTGSPPTSPATAQAPVSLALKQDSATLKGRSRNAGNYYREEGIDCTHLSSRKSCEDDIGFQRVEEPEIKRPRPKSAPALRHKMTPMPIPNPALQVQKYTPASEEHLSPELQEWAPYSPKRSARHSDGFVSSTLYTGGMSSGTVPRSLAPCPAVTAVMRNPIYTAWSHRVHTNNCPSVASQICHQHLHPSAQHQGRLSLDLSHKHSNEYSENPRTRASHGSNSLPSSARLGSSSNLQYRTERIKIPLTPRYPRSVMGSDRGSLSHSECSSPSLITPPQSPLNLETSSFASSQSQNSLSTLPRISISPVSAGERRKDRYLFRNRSFLRIPVAPRPRFSSLRSLRPYMEEPRHVKVQKGSEPLGISIVSGENGGIFVSKVTGGSIAHQAGLEYGDQLLEFNGINLRNATEQQARLIIGQQCDTITILAQYNPHMYQLGNHSRSSSRLEPVSNHSTPQGSGAATPDNHSIIDTVSEQDEGTMTPPSKQTTPTTSPRNSLRGPVDTNKRTPEPRTVVVKKSQVDLGIQICGGNLYGIFVSDVDDDSPAKGPDGLVLGDMILEYGSIDMRTKTAEEAYLEMLKPGENIKIKTQYRIEEFNRIKELPGDGFFIRALYDRVAEVEQDLSFKKDDILYVDDTLPQGNFGCWMAWQLDENAQKLERGQIPSKYMMDQEFYRRHSMSETKDENSSSKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDTISTDSIPFLDDSASLAYQRVQKVDCTSPRPVLILGPLLDAVKDMLVKESPGKFCRCPLEVMKASQQAIERGVKDCLFIDYKRRSGHFDVTTVASIKEITEKDCHCLLDIAPHAIERLHSVHIYPIVIFIRYKNAKQIKEQKDPIFLRDKVTQKHSKEQFETAQKIEQEYSKYFTGIVQGGALSSICTQIMTTVDQEQNKVLWIPAGPL", "length": 2045, "header": "tr|A0A8V0ZNH6-1|A0A8V0ZNH6_CHICK Isoform 1 of Discs large MAGUK scaffold protein 5 OS=Gallus gallus OX=9031 GN=DLG5 PE=4 SV=1 CANONICAL=A0A8V0ZNH6-1" }, "locus": { "chromosome": "6", "start_pos": 14075989, "end_pos": 13983015, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053761.1", "url": "https://www.ensembl.org/id/ENSGALT00010053761.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032371.1", "url": "https://www.ensembl.org/id/ENSGALP00010032371.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1064, "start_aa": "Thr", "end_pos": 1064, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1064", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1094, "start_aa": "Thr", "end_pos": 1094, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1094", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1392, "start_aa": "Thr", "end_pos": 1392, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1392", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423728", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423728", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" }, { "id": "R-GGA-9013424", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013424", "resource": "Reactome", "description": "RHOV GTPase cycle" }, { "id": "R-GGA-9696264", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696264", "resource": "Reactome", "description": "RND3 GTPase cycle" }, { "id": "R-GGA-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "positive regulation of smoothened signaling pathway", "id": "GO:0045880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "negative regulation of T cell proliferation", "id": "GO:0042130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "epithelial to mesenchymal transition", "id": "GO:0001837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "positive regulation of dendritic spine development", "id": "GO:0060999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060999", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "maintenance of cell polarity", "id": "GO:0030011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030011", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "positive regulation of hippo signaling", "id": "GO:0035332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "postsynapse organization", "id": "GO:0099173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099173", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1032, "end_pos": 1034, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1439, "end_pos": 1441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1522, "end_pos": 1524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1554, "end_pos": 1556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1567, "end_pos": 1569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1581, "end_pos": 1583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1800, "end_pos": 1802, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" }, { "start_pos": 916, "end_pos": 918, "annotation": "n_glycosylation_sequon" }, { "start_pos": 951, "end_pos": 953, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" }, { "id": "PS50209", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50209" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CARD", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 89, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZNH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" }, { "id": "PS50052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 1901, "end_pos": 2031, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZNH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 698, "end_pos": 788, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZNH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH6" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 1719, "end_pos": 1787, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1064, 1094, 1392 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPQ2-1", "uniprot_ac": "A0A8V0ZPQ2", "uniprot_id": "A0A8V0ZPQ2_CHICK", "mass": { "chemical_mass": 142720.0, "monoisotopic_mass": 142720.0 }, "refseq": {}, "gene_names": [ { "name": "FBRSL1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2" } ] } ], "protein_names": [ { "name": "Fibrosin like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPQ2", "url": 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"Protein Classification" ] }, { "id": "A0A8V0ZP93", "url": "https://www.orthodb.org/?gene=A0A8V0ZP93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP98", "url": "https://www.orthodb.org/?gene=A0A8V0ZP98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPP2", "url": "https://www.orthodb.org/?gene=A0A8V0ZPP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPP7", "url": "https://www.orthodb.org/?gene=A0A8V0ZPP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPQ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZPQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPQ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZPQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPR0", "url": "https://www.orthodb.org/?gene=A0A8V0ZPR0", "database": "OrthoDB", "categories": [ 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPR0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGKIRQSRRSRSQRDRVRRREAAARDPRNQSPSSGSEKEPSPGKENGAQNCTAPRGPPPAARTARPPRRRRRESSSQEEDLIDGFAIASFNTLEALEDMSLKPQERKEKWERHPGKKPRESENCVSAEPSENGHNNDAGSSEREAERGKERVKKKLPLKLTKQMKVPTSRSGRNSEEDSIREATSSQRSSSRDRLSDSSAQSLSGRGYSCDSESDVDDKASVGSEKLFSPAANKGPTLNDKPEAKAANVPKVSGLERSRELSTDVPFTLPIPSPQPVAAVVTSTSSAPTSSARASPLLKKEPVISAPAPPRLTPQPQPRPQSQPQPRPQSQPQLIPELRSQPPSHIPPPLNYQVHHQVAHNGLNNISRSSSASSATSISIPKHLPLSPQIPPHHSSGPALPLSISNLATSHFSLRSQTQHQHHPAMFATPPTLPPPPALPTNSLVIPGHPADTSLLISFNQPIMYCQPHSGILIGTLSQASLLPPPMSPHVENHHSMTCRNRECQVNIDSFSSIFVVLTGPRASVSFFFLSLSPLDHELLRQELNNRFLVQSSDRAAASLGPVPLLRAEFHQHQHTHQHQHTHQHTFTPFPSSLPQTPLMPPSAPPMVRTPAQNFDKYAPKLDNPYFRHSNTSNPIDVAGRPGTVHHTLLQKTPGVSDPYRPPVRKPGKWCAVHVQIAWQIYHHQQKIKQMQLDPHKIEIGGKLDLFSRPPAPGVFPGFHYPQDLARPLFSTTGATHPATTPFGPSPHHSSFLPTNHLADPFSRSSTFSGLGNLGSNAFGGLGSHALTHNNIFTHKDGPNLQNFNNPHEPWNRLHRTPPSFPTPPQWPKPSDSERSSSVTNHDRDREREPEKRDLSLSKDDRDKERDLMDKNRHSNRSSPASAPVTHQISNLIRSNSQTSSDPIRQVSLAERERSKEPEREHPDRLREPPIAEHKIKESRSPVKETPSHDKRPSEDNTKPVIQSVSPYSKPALSESLKLTNLMSKDMERKTELPSDLQKIKNDIKVKEERKEDSDVLVVGSEPSQHSRSVEHPPPPTLHGLSLPPSMAASMPISMGSVHQMNNMNVLDRSRMMTPLIGMNPLSGRERLPHPGFSWDPMRDPLRDAYHRSLDLHRRMDFQLRTDPIHRFPTTSGFYDHERSYRDREPHDYNHENLLEARREQERLRQVEERERLHLREELERARMHHLHSSPIESHLAHVPSFMPHLSGMHYPRLSPSTAMHNGILNRNPPTAALSAPPPLVPASSTRPASPRRTTPLTNSESRDYSPSRNPKEVEAR", "length": 1278, "header": "tr|A0A8V0ZPQ2-1|A0A8V0ZPQ2_CHICK Isoform 1 of Fibrosin like 1 OS=Gallus gallus OX=9031 GN=FBRSL1 PE=4 SV=1 CANONICAL=A0A8V0ZPQ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZH21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2/entry#A0A8V0ZH21-1", "sequence": { "sequence": "MKVPTSRSGRNSEEDSIREATSSQRSSSRDRLSDSSAQSLSGRGYSCDSESDVDDKASVGSEKLFSPAANKGPTLNDKPEAKAANVPKVSGLERSRELSTDVPFTLPIPSPQPVAAVVTSTSSAPTSSARASPLLKKEPVISAPAPPRLTPQPQPRPQSQPQPRPQSQPQLIPELRSQPPSHIPPPLNYQVHHQVAHNGLNNISRSSSASSATSISIPKHLPLSPQIPPHHSSGPALPLSISNLATSHFSLRSQTQHQHHPAMFATPPTLPPPPALPTNSLVIPGHPADTSLLISFNQPIMYCQPHSGILIGTLSQASLLPPPMSPHVENHHSMTCRNRECQFDKYAPKLDNPYFRHSNFFPTYPPAMPGMPPMLPHSGPFGSLQGAFQPKTSNPIDVAGRPGTVHHTLLQKTPGVSDPYRPPVRKPGKWCAVHVQIAWQIYHHQQKIKQMQLDPHKIEIGGKLDLFSRPPAPGVFPGFHYPQDLARPLFSTTGATHPATTPFGPSPHHSSFLPTNHLADPFSRSSTFSGLGNLGSNAFGGLGSHALTHNNIFTHKDGPNLQNFNNPHEPWNRLHRTPPSFPTPPQWPKPSDSERSSSVTNHDRDREREPEKRDLSLSKDDRDKERDLMDKNRHSNRSSPASAPVTHQISNLIRSNSQTSSDPIRQVSLAERERSKEPEREHPDRLREPPIAEHKIKESRSPVKETPSHDKRPSEDNTKPVIQSVSPYSKPALSESLKLTNLMSKDMERKTELPSDLQKIKNDIKVKEERKEDSDVLVVGSEPSQHSRSVEHPPPPTLHGLSLPPSMAASMPISMGSVHQMNNMNVLDRSRMMTPLIGMNPLSGRERLPHPGFSWDPMRDPLRDAYHRSLDLHRRMDFQLRTDPIHRFPTTSGFYDHERSYRDREPHDYNHENLLEARREQERLRQVEERERLHLREELERARMHHLHSSPIESHLAHVPSFMPHLSGMHYPRLSPSTAMHNGILNRNPPTAALSAPPPLVPASSTRPASPRRTTPLTNSESRDYSPSRNPKEVEAR", "length": 1037, "header": "tr|A0A8V0ZH21-1|A0A8V0ZPQ2_CHICK Computationally mapped isoform of Fibrosin like 1 OS=Gallus gallus OX=9031 GN=FBRSL1 PE=4 SV=1 CANONICAL=A0A8V0ZPQ2-1" }, "locus": { "chromosome": "15", "start_pos": 1823564, "end_pos": 1576893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054077.1", "url": "https://www.ensembl.org/id/ENSGALT00010054077.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032608.1", "url": "https://www.ensembl.org/id/ENSGALP00010032608.1" } ] } }, { "isoform_ac": "A0A8V0ZP93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2/entry#A0A8V0ZP93-1", "sequence": { "sequence": "MDGKIRQSRRSRSQRDRVRRREAAARDPRNQSPSSGSEKEPSPGKENGAQNCTAPRGPPPAARTARPPRRRRRESSSQEEDLIDGFAIASFNTLEALEKDMSLKPQERKEKWERHPGKKPRESENCVSAEPSENGHNNDAGSSEREAERGKERVKKKLPLKLTKQMKVPTSRSGRNSEEDSIREATSSQRSSSRDRLSDSSAQSLSGRGYSCDSESDVDDKTSTELELTRIRSALITSKASVGSEKLFSPAANKGPTLNDKPEAKAANVPKVSGLERSRELSTDVPFTLPIPSPQPVAAVVTSTSSAPTSSARASPLLKKEPVISAPAPPRLTPQPQPRPQSQPQPRPQSQPQLIPELRSQPPSHIPPPLNYQVHHQVAHNGLNNISRSSSASSATSISIPKHLPLSPQIPPHHSSGPALPLSISNLATSHFSLRSQTQHQHHPAMFATPPTLPPPPALPTNSLVIPGHPADTSLLISFNQPIMYCQPHSGILIGTLSQASLLPPPMSPHVENHHSMTCRNRECQFDKYAPKLDNPYFRHSNFFPTYPPAMPGMPPMLPHSGPFGSLQGAFQPKTSNPIDVAGRPGTVHHTLLQKTPGVSDPYRPPVRKPGKWCAVHVQIAWQIYHHQQKIKQMQLDPHKIEIGGKLDLFSRPPAPGVFPGFHYPQDLARPLFSTTGATHPATTPFGPSPHHSSFLPTNHLADPFSRSSTFSGLGNLGSNAFGGLGSHALTHNNIFTHKDGPNLQNFNNPHEPWNRLHRTPPSFPTPPQWPKPSDSERSSSVTNHDRDREREPEKRDLSLSKDDRDKERDLMDKNRHSNRSSPASAPVTHQISNLIRSNSQTSSDPIRQVSLAERERSKEPEREHPDRLREPPIAEHKIKESRSPVKETPSHDKRPSEDNTKPVIQSVSPYSKPALSESLKLTNLMSKDMERKTELPSDLQKIKNDIKVKEERKEDSDVLVVGSEPSQHSRSVEHPPPPTLHGLSLPPSMAASMPISMGSVHQMNNMNVLDRSRMMTPLIGMNPLSGRERLPHPGFSWDPMRDPLRDAYHRSLDLHRRMDFQLRTDPIHRFPTTSGFYDHERSYRDREPHDYNHENLLEARREQERLRQVEERERLHLREELERARMHHLHSSPIESHLAHVPSFMPHLSGMHYPRLSPSTAMHNGILNRNPPTAALSAPPPLVPASSTRPASPRRTTPLTNSESRDYSPSRNPKEVEAR", "length": 1220, "header": "tr|A0A8V0ZP93-1|A0A8V0ZP93_CHICK Computationally mapped isoform of Fibrosin like 1 OS=Gallus gallus OX=9031 GN=FBRSL1 PE=4 SV=1 CANONICAL=A0A8V0ZPQ2-1" }, "locus": { "chromosome": "15", "start_pos": 1993610, "end_pos": 1576893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054108.1", "url": "https://www.ensembl.org/id/ENSGALT00010054108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032638.1", "url": "https://www.ensembl.org/id/ENSGALP00010032638.1" } ] } }, { "isoform_ac": "A0A8V0ZP98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2/entry#A0A8V0ZP98-1", "sequence": { "sequence": "MDGKIRQSRRSRSQRDRVRRREAAARDPRNQSPSSGSEKEPSPGKENGAQNCTAPRGPPPAARTARPPRRRRRESSSQEEDLIDGFAIASFNTLEALEKDMSLKPQERKEKWERHPGKKPRESENCVSAEPSENGHNNDAGSSEREAERGKERVKKKLPLKLTKQMKVPTSRSGRNSEEDSIREATSSQRSSSRDRLSDSSAQSLSGRGYSCDSESDVDDKASVGSEKLFSPAANKGPTLNDKPEAKAANVPKVSGLERSRELSTDVPFTLPIPSPQPVAAVVTSTSSAPTSSARASPLLKKEPVISAPAPPRLTPQPQPRPQSQPQPRPQSQPQLIPELRSQPPSHIPPPLNYQVHHQVAHNGLNNISRSSSASSATSISIPKHLPLSPQIPPHHSSGPALPLSISNLATSHFSLRSQTQHQHHPAMFATPPTLPPPPALPTNSLVIPGHPADTSLLISFNQPIMYCQPHSGILIGTLSQASLLPPPMSPHVENHHSMTCRNRECQFDKYAPKLDNPYFRHSNFFPTYPPAMPGMPPMLPHSGPFGSLQGAFQPKTSNPIDVAGRPGTVHHTLLQKTPGVSDPYRPPVRKPGKWCAVHVQIAWQIYHHQQKIKQMQLDPHKIEIGGKLDLFSRPPAPGVFPGFHYPQDLARPLFSTTGATHPATTPFGPSPHHSSFLPTNHLADPFSRSSTFSGLGNLGSNAFGGLGSHALTHNNIFTHKDGPNLQNFNNPHEPWNRLHRTPPSFPTPPQWPKPSDSERSSSVTNHDRDREREPEKRDLSLSKDDRDKERDLMDKNRHSNRSSPASAPVTHQISNLIRSNSQTSSDPIRQVSLAERERSKEPEREHPDRLREPPIAEHKIKESRSPVKETPSHDKRPSEDNTKPVIQSVSPYSKPALSESLKLTNLMSKDMERKTELPSDLQKIKNDIKVKEERKEDSDVLVVGSEPSQHSRSVEHPPPPTLHGLSLPPSMAASMPISMGSVHQMNNMNVLDRSRMMTPLIGMNPLSGRERLPHPGFSWDPMRDPLRDAYHRSLDLHRRMDFQLRTDPIHRFPTTSGFYDHERSYRDREPHDYNHENLLEARREQERLRQVEERERLHLREELERARMHHLHSSPIESHLAHVPSFMPHLSGMHYPRLSPSTAMHNGILNRNPPTAALSAPPPLVPASSTRPASPRRTTPLTNSESRDYSPSRNPKEVEAR", "length": 1202, "header": "tr|A0A8V0ZP98-1|A0A8V0ZP98_CHICK Computationally mapped isoform of Fibrosin like 1 OS=Gallus gallus OX=9031 GN=FBRSL1 PE=4 SV=1 CANONICAL=A0A8V0ZPQ2-1" }, "locus": { "chromosome": "15", "start_pos": 1993610, "end_pos": 1576893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054112.1", "url": "https://www.ensembl.org/id/ENSGALT00010054112.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032643.1", "url": "https://www.ensembl.org/id/ENSGALP00010032643.1" } ] } }, { "isoform_ac": "A0A8V0ZPP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2/entry#A0A8V0ZPP2-1", "sequence": { "sequence": "MKVPTSRSGRNSEEDSIREATSSQRSSSRDRLSDSSAQSLSGRGYSCDSESDVDDKASVGSEKLFSPAANKGPTLNDKPEAKAANVPKVSGLERSRELSTDVPFTLPIPSPQPVAAVVTSTSSAPTSSARASPLLKKEPVISAPAPPRLTPQPQPRPQSQPQPRPQSQPQLIPELRSQPPSHIPPPLNYQVHHQVAHNGLNNISRSSSASSATSISIPKHLPLSPQIPPHHSSGPALPLSISNLATSHFSLRSQTQHQHHPAMFATPPTLPPPPALPTNSLVIPGHPADTSLLISFNQPIMYCQPHSGILIGTLSQASLLPPPMSPHVENHHSMTCRNRECQFDKYAPKLDNPYFRHSNFFPTYPPAMPGMPPMLPHSGPFGSLQGAFQPKTSNPIDVAGRPGTVHHTLLQKTPGVSDPYRPPVRKPGKWCAVHVQIAWQIYHHQQKIKQMQLDPHKIEIGGKLDLFSRPPAPGVFPGFHYPQDLARPLFSTTDPFSRSSTFSGLGNLGSNAFGGLGSHALTHNNIFTHKDGPNLQNFNNPHEPWNRLHRTPPSFPTPPQWPKPSDSERSSSVTNHDRDREREPEKRDLSLSKDDRDKERDLMDKNRHSNRSSPASAPVTHQISNLIRSNSQTSSDPIRQVSLAERERSKEPEREHPDRLREPPIAEHKIKESRSPVKETPSHDKRPSEDNTKPVIQSVSPYSKPALSESLKLTNLMSKDMERKTELPSDLQKIKNDIKVKEERKEDSDVLVVGSEPSQHSRSVEHPPPPTLHGLSLPPSMAASMPISMGSVHQMNNMNVLDRSRMMTPLIGMNPLSGRERLPHPGFSWDPMRDPLRDAYHRSLDLHRRMDFQLRTDPIHRFPTTSGFYDHERSYRDREPHDYNHENLLEARREQERLRQVEERERLHLREELERARMHHLHSSPIESHLAHVPSFMPHLSGMHYPRLSPSTAMHNGILNRNPPTAALSAPPPLVPASSTRPASPRRTTPLTNSESRDYSPSRNPKEVEAR", "length": 1011, "header": "tr|A0A8V0ZPP2-1|A0A8V0ZPP2_CHICK Computationally mapped isoform of Fibrosin like 1 OS=Gallus gallus OX=9031 GN=FBRSL1 PE=4 SV=1 CANONICAL=A0A8V0ZPQ2-1" }, "locus": { "chromosome": "15", "start_pos": 1823564, "end_pos": 1576893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054080.1", "url": "https://www.ensembl.org/id/ENSGALT00010054080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032611.1", "url": "https://www.ensembl.org/id/ENSGALP00010032611.1" } ] } }, { "isoform_ac": "A0A8V0ZPP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2/entry#A0A8V0ZPP7-1", "sequence": { "sequence": "MHWSLLFAERKKDMSLKPQERKEKWERHPGKKPRESENCVSAEPSENGHNNDAGSSEREAERGKERVKKKLPLKLTKQMKVPTSRSGRNSEEDSIREATSSQRSSSRDRLSDSSAQSLSGRGYSCDSESDVDDKASVGSEKLFSPAANKGPTLNDKPEAKAANVPKVSGLERSRELSTDVPFTLPIPSPQPVAAVVTSTSSAPTSSARASPLLKKEPVISAPAPPRLTPQPQPRPQSQPQPRPQSQPQLIPELRSQPPSHIPPPLNYQVHHQVAHNGLNNISRSSSASSATSISIPKHLPLSPQIPPHHSSGPALPLSISNLATSHFSLRSQTQHQHHPAMFATPPTLPPPPALPTNSLVIPGHPADTSLLISFNQPIMYCQPHSGILIGTLSQASLLPPPMSPHVENHHSMTCRNRECQFDKYAPKLDNPYFRHSNFFPTYPPAMPGMPPMLPHSGPFGSLQGAFQPKTSNPIDVAGRPGTVHHTLLQKTPGVSDPYRPPVRKPGKWCAVHVQIAWQIYHHQQKIKQMQLDPHKIEIGGKLDLFSRPPAPGVFPGFHYPQDLARPLFSTTGATHPATTPFGPSPHHSSFLPTNHLADPFSRSSTFSGLGNLGSNAFGGLGSHALTHNNIFTHKDGPNLQNFNNPHEPWNRLHRTPPSFPTPPQWPKPSDSERSSSVTNHDRDREREPEKRDLSLSKDDRDKERDLMDKNRHSNRSSPASAPVTHQISNLIRSNSQTSSDPIRQVSLAERERSKEPEREHPDRLREPPIAEHKIKESRSPVKETPSHDKRPSEDNTKPVIQSVSPYSKPALSESLKLTNLMSKDMERKTELPSDLQKIKNDIKVKEERKEDSDVLVVGSEPSQHSRSVEHPPPPTLHGLSLPPSMAASMPISMGSVHQMNNMNVLDRSRMMTPLIGMNPLSGRERLPHPGFSWDPMRDPLRDAYHRSLDLHRRMDFQLRTDPIHRFPTTSGFYDHERSYRDREPHDYNHENLLEARREQERLRQVEERERLHLREELERARMHHLHSSPIESHLAHVPSFMPHLSGMHYPRLSPSTAMHNGILNRNPPTAALSAPPPLVPASSTRPASPRRTTPLTNSESRDYSPSRNPKEVEAR", "length": 1115, "header": "tr|A0A8V0ZPP7-1|A0A8V0ZPP7_CHICK Computationally mapped isoform of Fibrosin like 1 OS=Gallus gallus OX=9031 GN=FBRSL1 PE=4 SV=1 CANONICAL=A0A8V0ZPQ2-1" }, "locus": { "chromosome": "15", "start_pos": 1898555, "end_pos": 1576893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054085.1", "url": "https://www.ensembl.org/id/ENSGALT00010054085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032616.1", "url": "https://www.ensembl.org/id/ENSGALP00010032616.1" } ] } }, { "isoform_ac": "A0A8V0ZPQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2/entry#A0A8V0ZPQ2-1", "sequence": { "sequence": "MDGKIRQSRRSRSQRDRVRRREAAARDPRNQSPSSGSEKEPSPGKENGAQNCTAPRGPPPAARTARPPRRRRRESSSQEEDLIDGFAIASFNTLEALEDMSLKPQERKEKWERHPGKKPRESENCVSAEPSENGHNNDAGSSEREAERGKERVKKKLPLKLTKQMKVPTSRSGRNSEEDSIREATSSQRSSSRDRLSDSSAQSLSGRGYSCDSESDVDDKASVGSEKLFSPAANKGPTLNDKPEAKAANVPKVSGLERSRELSTDVPFTLPIPSPQPVAAVVTSTSSAPTSSARASPLLKKEPVISAPAPPRLTPQPQPRPQSQPQPRPQSQPQLIPELRSQPPSHIPPPLNYQVHHQVAHNGLNNISRSSSASSATSISIPKHLPLSPQIPPHHSSGPALPLSISNLATSHFSLRSQTQHQHHPAMFATPPTLPPPPALPTNSLVIPGHPADTSLLISFNQPIMYCQPHSGILIGTLSQASLLPPPMSPHVENHHSMTCRNRECQVNIDSFSSIFVVLTGPRASVSFFFLSLSPLDHELLRQELNNRFLVQSSDRAAASLGPVPLLRAEFHQHQHTHQHQHTHQHTFTPFPSSLPQTPLMPPSAPPMVRTPAQNFDKYAPKLDNPYFRHSNTSNPIDVAGRPGTVHHTLLQKTPGVSDPYRPPVRKPGKWCAVHVQIAWQIYHHQQKIKQMQLDPHKIEIGGKLDLFSRPPAPGVFPGFHYPQDLARPLFSTTGATHPATTPFGPSPHHSSFLPTNHLADPFSRSSTFSGLGNLGSNAFGGLGSHALTHNNIFTHKDGPNLQNFNNPHEPWNRLHRTPPSFPTPPQWPKPSDSERSSSVTNHDRDREREPEKRDLSLSKDDRDKERDLMDKNRHSNRSSPASAPVTHQISNLIRSNSQTSSDPIRQVSLAERERSKEPEREHPDRLREPPIAEHKIKESRSPVKETPSHDKRPSEDNTKPVIQSVSPYSKPALSESLKLTNLMSKDMERKTELPSDLQKIKNDIKVKEERKEDSDVLVVGSEPSQHSRSVEHPPPPTLHGLSLPPSMAASMPISMGSVHQMNNMNVLDRSRMMTPLIGMNPLSGRERLPHPGFSWDPMRDPLRDAYHRSLDLHRRMDFQLRTDPIHRFPTTSGFYDHERSYRDREPHDYNHENLLEARREQERLRQVEERERLHLREELERARMHHLHSSPIESHLAHVPSFMPHLSGMHYPRLSPSTAMHNGILNRNPPTAALSAPPPLVPASSTRPASPRRTTPLTNSESRDYSPSRNPKEVEAR", "length": 1278, "header": "tr|A0A8V0ZPQ2-1|A0A8V0ZPQ2_CHICK Isoform 1 of Fibrosin like 1 OS=Gallus gallus OX=9031 GN=FBRSL1 PE=4 SV=1 CANONICAL=A0A8V0ZPQ2-1" }, "locus": { "chromosome": "15", "start_pos": 1993610, "end_pos": 1576893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054090.1", "url": "https://www.ensembl.org/id/ENSGALT00010054090.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032621.1", "url": "https://www.ensembl.org/id/ENSGALP00010032621.1" } ] } }, { "isoform_ac": "A0A8V0ZPQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2/entry#A0A8V0ZPQ6-1", "sequence": { "sequence": "MDGKIRQSRRSRSQRDRVRRREAAARDPRNQSPSSGSEKEPSPGKENGAQNCTAPRGPPPAARTARPPRRRRRESSSQEEDLIDGFAIASFNTLEALEDMSLKPQERKEKWERHPGKKPRESENCVSAEPSENGHNNDAGSSEREAERGKERVKKKLPLKLTKQMKVPTSRSGRNSEEDSIREATSSQRSSSRDRLSDSSAQSLSGRGYSCDSESDVDDKASVGSEKLFSPAANKGPTLNDKPEAKAANVPKVSGLERSRELSTDVPFTLPIPSPQPVAAVVTSTSSAPTSSARASPLLKKEPVISAPAPPRLTPQPQPRPQSQPQPRPQSQPQLIPELRSQPPSHIPPPLNYQVHHQVAHNGLNNISRSSSASSATSISIPKHLPLSPQIPPHHSSGPALPLSISNLATSHFSLRSQTQHQHHPAMFATPPTLPPPPALPTNSLVIPGHPADTSLLISFNQPIMYCQPHSGILIGTLSQASLLPPPMSPHVENHHSMTCRNRECQFDKYAPKLDNPYFRHSNFFPTYPPAMPGMPPMLPHSGPFGSLQGAFQPKTSNPIDVAGRPGTVHHTLLQKTPGVSDPYRPPVRVSKKPGKWCAVHVQIAWQIYHHQQKIKQMQLDPHKIEIGGKLDLFSRPPAPGVFPGFHYPQDLARPLFSTTGATHPATTPFGPSPHHSSFLPTNHLAAHNNIFTHKDGPNLQNFNNPHEPWNRLHRTPPSFPTPPQWPKPSDSERSSSVTNHDRDREREPEKRDLSLSKDDRDKERDLMDKNRHSNRSSPASAPVTHQISNLIRSNSQTSSDPIRQVSLAERERSKEPEREHPDRLREPPIAEHKIKESRSPVKETPSHDKRPSEDNTKPVIQSVSPYSKPALSESLKLTNLMSKDMERKTELPSDLQKIKNDIKVKEERKEDSDVLVVGSEPSQHSRSVEHPPPPTLHGLSLPPSMAASMPISMGSVHQMNNMNVLDRSRMMTPLIGMNPLSGRERLPHPGFSWDPMRDPLRDAYHRSLDLHRRMDFQLRTDPIHRFPTTSGFYDHERSYRDREPHDYNHENLLEARREQERLRQVEERERLHLREELERARMHHLHSSPIESHLAHVPSFMPHLSGMHYPRLSPSTAMHNGILNRNPPTAALSAPPPLVPASSTRPASPRRTTPLTNSESRDYSPSRNPKEVEAR", "length": 1176, "header": "tr|A0A8V0ZPQ6-1|A0A8V0ZPQ6_CHICK Computationally mapped isoform of Fibrosin like 1 OS=Gallus gallus OX=9031 GN=FBRSL1 PE=4 SV=1 CANONICAL=A0A8V0ZPQ2-1" }, "locus": { "chromosome": "15", "start_pos": 1993610, "end_pos": 1576893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054095.1", "url": "https://www.ensembl.org/id/ENSGALT00010054095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032626.1", "url": "https://www.ensembl.org/id/ENSGALP00010032626.1" } ] } }, { "isoform_ac": "A0A8V0ZPR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2/entry#A0A8V0ZPR0-1", "sequence": { "sequence": "MDGKIRQSRRSRSQRDRVRRREAAARDPRNQSPSSGSEKEPSPGKENGAQNCTAPRGPPPAARTARPPRRRRRESSSQEEDLIDGFAIASFNTLEALEKDMSLKPQERKEKWERHPGKKPRESENCVSAEPSENGHNNDAGSSEREAERGKERVKKKLPLKLTKQMKVPTSRSGRNSEEDSIREATSSQRSSSRDRLSDSSAQSLSGRGYSCDSESDVDDKTSTELELTRIRSALITSKASVGSEKLFSPAANKGPTLNDKPEAKAANVPKVSGLERSRELSTDVPFTLPIPSPQPVAAVVTSTSSAPTSSARASPLLKKEPVISAPAPPRLTPQPQPRPQSQPQPRPQSQPQLIPELRSQPPSHIPPPLNYQVHHQVAHNGLNNISRSSSASSATSISIPKHLPLSPQIPPHHSSGPALPLSISNLATSHFSLRSQTQHQHHPAMFATPPTLPPPPALPTNSLVIPGHPADHELLRQELNNRFLVQSSDRAAASLGPVPLLRAEFHQHQHTHQHQHTHQHTFTPFPSSLPQTPLMPPSAPPMFDKYAPKLDNPYFRHSNFFPTYPPAMPGMPPMLPHSGPFGSLQGAFQPKTSNPIDVAGRPGTVHHTLLQKTPGVSDPYRPPVRKPGKWCAVHVQIAWQIYHHQQKIKQMQLDPHKIEIGGKLDLFSRPPAPGVFPGFHYPQDLARPLFSTTGATHPATTPFGPSPHHSSFLPTNHLADPFSRSSTFSGLGNLGSNAFGGLGSHALTHNNIFTHKDGPNLQNFNNPHEPWNRLHRTPPSFPTPPQWPKPSDSERSSSVTNHDRDREREPEKRDLSLSKDDRDKERDLMDKNRHSNRSSPASAPVTHQISNLIRSNSQTSSDPIRQVSLAERERSKEPEREHPDRLREPPIAEHKIKESRSPVKETPSHDKRPSEDNTKPVIQSVSPYSKPALSESLKLTNLMSKDMERKTELPSDLQKIKNDIKVKEERKEDSDVLVVGSEPSQHSRSVEHPPPPTLHGLSLPPSMAASMPISMGSVHQMNNMNVLDRSRMMTPLIGMNPLSGRERLPHPGFSWDPMRDPLRDAYHRSLDLHRRMDFQLRTDPIHRFPTTSGFYDHERSYRDREPHDYNHENLLEARREQERLRQVEERERLHLREELERARMHHLHSSPIESHLAHVPSFMPHLSGMHYPRLSPSTAMHNGILNRNPPTAALSAPPPLVPASSTRPASPRRTTPLTNSESRDYSPSRNPKEVEAR", "length": 1238, "header": "tr|A0A8V0ZPR0-1|A0A8V0ZPR0_CHICK Computationally mapped isoform of Fibrosin like 1 OS=Gallus gallus OX=9031 GN=FBRSL1 PE=4 SV=1 CANONICAL=A0A8V0ZPQ2-1" }, "locus": { "chromosome": "15", "start_pos": 1993610, "end_pos": 1576893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054101.1", "url": "https://www.ensembl.org/id/ENSGALT00010054101.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032632.1", "url": "https://www.ensembl.org/id/ENSGALP00010032632.1" } ] } }, { "isoform_ac": "A0A8V0ZUW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ2/entry#A0A8V0ZUW6-1", "sequence": { "sequence": "MDGKIRQSRRSRSQRDRVRRREAAARDPRNQSPSSGSEKEPSPGKENGAQNCTAPRGPPPAARTARPPRRRRRESSSQEEDLIDGFAIASFNTLEALEKDMSLKPQERKEKWERHPGKKPRESENCVSAEPSENGHNNDAGSSEREAERGKERVKKKLPLKLTKQMKVPTSRSGRNSEEDSIREATSSQRSSSRDRLSDCDSESDVDDKTSTELELTRIRSALITSKASVGSEKLFSPAANKGPTLNDKPEAKAANVPKVSGLERSRELSTDVPFTLPIPSPQPVAAVVTSTSSAPTSSARASPLLKKEPVISAPAPPRLTPQPQPRPQSQPQPRPQSQPQLIPELRSQPPSHIPPPLNYQVHHQVAHNGLNNISRSSSASSATSISIPKHLPLSPQIPPHHSSGPALPLSISNLATSHFSLRSQTQHQHHPAMFATPPTLPPPPALPTNSLVIPGHPADTSLLISFNQPIMYCQPHSGILIGTLSQASLLPPPMSPHVENHHSMTCRNRECQFDKYAPKLDNPYFRHSNFFPTYPPAMPGMPPMLPHSGPFGSLQGAFQPKTSNPIDVAGRPGTVHHTLLQKTPGVSDPYRPPVRKPGKWCAVHVQIAWQIYHHQQKIKQMQLDPHKIEIGGKLDLFSRPPAPGVFPGFHYPQDLARPLFSTTGATHPATTPFGPSPHHSSFLPTNHLADPFSRSSTFSGLGNLGSNAFGGLGSHALTHNNIFTHKDGPNLQNFNNPHEPWNRLHRTPPSFPTPPQWPKPSDSERSSSVTNHDRDREREPEKRDLSLSKDDRDKERDLMDKNRHSNRSSPASAPVTHQISNLIRSNSQTSSDPIRQVSLAERERSKEPEREHPDRLREPPIAEHKIKESRSPVKETPSHDKRPSEDNTKPVIQSVSPYSKPALSESLKLTNLMSKDMERKTELPSDLQKIKNDIKVKEERKEDSDVLVVGSEPSQHSRSVEHPPPPTLHGLSLPPSMAASMPISMGSVHQMNNMNVLDRSRMMTPLIGMNPLSGRERLPHPGFSWDPMRDPLRDAYHRSLDLHRRMDFQLRTDPIHRFPTTSGFYDHERSYRDREPHDYNHENLLEARREQERLRQVEERERLHLREELERARMHHLHSSPIESHLAHVPSFMPHLSGMHYPRLSPSTAMHNGILNRNPPTAALSAPPPLVPASSTRPASPRRTTPLTNSESRDYSPSRNPKEVEAR", "length": 1208, "header": "tr|A0A8V0ZUW6-1|A0A8V0ZPQ2_CHICK Computationally mapped isoform of Fibrosin like 1 OS=Gallus gallus OX=9031 GN=FBRSL1 PE=4 SV=1 CANONICAL=A0A8V0ZPQ2-1" }, "locus": { "chromosome": "15", "start_pos": 1993610, "end_pos": 1576893, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054098.1", "url": "https://www.ensembl.org/id/ENSGALT00010054098.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032629.1", "url": "https://www.ensembl.org/id/ENSGALP00010032629.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 824, "start_aa": "Thr", "end_pos": 824, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr824", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 877, "end_pos": 879, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 824 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 632, "end_pos": 634 }, { "start_pos": 877, "end_pos": 879 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZP79-1", "uniprot_ac": "A0A8V0ZP79", "uniprot_id": "A0A8V0ZP79_CHICK", "mass": { "chemical_mass": 71603.0, "monoisotopic_mass": 71603.0 }, "refseq": {}, "gene_names": [ { "name": "FUBP1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ] } ], "protein_names": [ { "name": "Far upstream element-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPE4#function" }, { "database": "UniProtKB", "id": "ARBA00053225", "url": "https://www.uniprot.org/uniprotkb/ARBA00053225#function" }, { "database": "UniProtKB", "id": "A0A8V0ZH42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH42#function" }, { "database": "UniProtKB", "id": "A0A8V0ZMG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZMM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79#function" }, { "database": "UniProtKB", "id": "A0A8V0ZUV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUV1#function" }, { "database": "UniProtKB", "id": "A0A8V0ZUZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUZ7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FUBP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79", "locus": { "chromosome": "8", "start_pos": 18617091, "end_pos": 18579813, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022228", "url": "https://www.ensembl.org/id/ENSGALG00010022228" } ] } } ], "crossref": [ { "id": "A0A8V0ZP79", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP79", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22478", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22478", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22481", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22481", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22484", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22484", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22487", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22487", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424551", "url": "https://www.ncbi.nlm.nih.gov/gene/424551", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH42", "url": "https://www.orthodb.org/?gene=A0A8V0ZH42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMG8", "url": "https://www.orthodb.org/?gene=A0A8V0ZMG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZMM5", "url": "https://www.orthodb.org/?gene=A0A8V0ZMM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP79", "url": "https://www.orthodb.org/?gene=A0A8V0ZP79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPE4", "url": "https://www.orthodb.org/?gene=A0A8V0ZPE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUV1", "url": "https://www.orthodb.org/?gene=A0A8V0ZUV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUZ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZUZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZH42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMG8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZMM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPE4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSRPSPPQAASGAGSSGGASMADYSTVPPPASGAPGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSMNSNDYGYGGQKRPLEDGDGSWTSPSSTTHWEGMPSPFKDQPDAKKVAPQNDSFGNQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKMFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVVPGPHGPPGPPGPGAPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQPPNPPDPGKPGTDPNSAAWAAYYAHYYQQQAQPPPAAPPGGPATTQTNGQGDQPNPAPAGQVDYTKAWEEYYKKMGQAVPAPAGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ", "length": 685, "header": "tr|A0A8V0ZP79-1|A0A8V0ZP79_CHICK Isoform 1 of Far upstream element-binding protein 1 OS=Gallus gallus OX=9031 GN=FUBP1 PE=1 SV=1 CANONICAL=A0A8V0ZP79-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZH42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79/entry#A0A8V0ZH42-1", "sequence": { "sequence": "MADYSTVPPPASGAPGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSMNSNDYGYGGQKRPLEDGAFGNQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKMFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVVPGPHGPPGPPGPGAPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQPPNPPDPGKPGTDPNSAAWAAYYAHYYQQQAQPPPAAPPGGPATTQTNGQGDQPNPAPAGQVDYTKAWEEYYKKMGQAVPAPAGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ", "length": 614, "header": "tr|A0A8V0ZH42-1|A0A8V0ZP79_CHICK Computationally mapped isoform of Far upstream element-binding protein 1 OS=Gallus gallus OX=9031 GN=FUBP1 PE=1 SV=1 CANONICAL=A0A8V0ZP79-1" }, "locus": { "chromosome": "8", "start_pos": 18600432, "end_pos": 18580087, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054097.1", "url": "https://www.ensembl.org/id/ENSGALT00010054097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032628.1", "url": "https://www.ensembl.org/id/ENSGALP00010032628.1" } ] } }, { "isoform_ac": "A0A8V0ZMG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79/entry#A0A8V0ZMG8-1", "sequence": { "sequence": "MADYSTVPPPASGAPGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSMNSNDYGYGGQKRPLEDGDGSWTSPSSTTHWEGMPSPFKDQPDAKKVAPQNDSFGNQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKMFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVVPGPHGPPGPPGPGAPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQPPNPPDPGKPGTDPNSAAWAAYYAHYYQQQAQPPPAAPPGGPATTQTNGQGDQPNPAPAGQVDYTKAWEEYYKKMGQAVPAPAGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKKQQC", "length": 679, "header": "tr|A0A8V0ZMG8-1|A0A8V0ZP79_CHICK Computationally mapped isoform of Far upstream element-binding protein 1 OS=Gallus gallus OX=9031 GN=FUBP1 PE=1 SV=1 CANONICAL=A0A8V0ZP79-1" }, "locus": { "chromosome": "8", "start_pos": 18603497, "end_pos": 18580087, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054106.1", "url": "https://www.ensembl.org/id/ENSGALT00010054106.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032641.1", "url": "https://www.ensembl.org/id/ENSGALP00010032641.1" } ] } }, { "isoform_ac": "A0A8V0ZMM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79/entry#A0A8V0ZMM5-1", "sequence": { "sequence": "MADYSTVPPPASGAPGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSMNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGNQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKMFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVVPGPHGPPGPPGPGAPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQPPNPPDPGKPGTDPNSAAWAAYYAHYYQQQAQPPPAAPPGGPATTQTNGQGDQPNPAPAGQVDYTKAWEEYYKKMGQAVPAPAGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQTFNHH", "length": 646, "header": "tr|A0A8V0ZMM5-1|A0A8V0ZP79_CHICK Computationally mapped isoform of Far upstream element-binding protein 1 OS=Gallus gallus OX=9031 GN=FUBP1 PE=1 SV=1 CANONICAL=A0A8V0ZP79-1" }, "locus": { "chromosome": "8", "start_pos": 18615819, "end_pos": 18580087, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054187.1", "url": "https://www.ensembl.org/id/ENSGALT00010054187.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032712.1", "url": "https://www.ensembl.org/id/ENSGALP00010032712.1" } ] } }, { "isoform_ac": "A0A8V0ZP79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79/entry#A0A8V0ZP79-1", "sequence": { "sequence": "MKSRPSPPQAASGAGSSGGASMADYSTVPPPASGAPGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSMNSNDYGYGGQKRPLEDGDGSWTSPSSTTHWEGMPSPFKDQPDAKKVAPQNDSFGNQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKMFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVVPGPHGPPGPPGPGAPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQPPNPPDPGKPGTDPNSAAWAAYYAHYYQQQAQPPPAAPPGGPATTQTNGQGDQPNPAPAGQVDYTKAWEEYYKKMGQAVPAPAGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ", "length": 685, "header": "tr|A0A8V0ZP79-1|A0A8V0ZP79_CHICK Isoform 1 of Far upstream element-binding protein 1 OS=Gallus gallus OX=9031 GN=FUBP1 PE=1 SV=1 CANONICAL=A0A8V0ZP79-1" }, "locus": { "chromosome": "8", "start_pos": 18600432, "end_pos": 18579920, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054091.1", "url": "https://www.ensembl.org/id/ENSGALT00010054091.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032622.1", "url": "https://www.ensembl.org/id/ENSGALP00010032622.1" } ] } }, { "isoform_ac": "A0A8V0ZPE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79/entry#A0A8V0ZPE4-1", "sequence": { "sequence": "MADYSTVPPPASGAPGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSMNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGNQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKMFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVVPGPHGPPGPPGPGAPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQPPNPPDPGKPGTDPNSAAWAAYYAHYYQQQAQPPPAAPPGGPATTQTNGQGDQPNPAPAGQVDYTKAWEEYYKKMGQAVPAPAGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKKQQTFNHH", "length": 662, "header": "tr|A0A8V0ZPE4-1|A0A8V0ZPE4_CHICK Computationally mapped isoform of Far upstream element-binding protein 1 OS=Gallus gallus OX=9031 GN=FUBP1 PE=1 SV=1 CANONICAL=A0A8V0ZP79-1" }, "locus": { "chromosome": "8", "start_pos": 18615819, "end_pos": 18580087, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054169.1", "url": "https://www.ensembl.org/id/ENSGALT00010054169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032699.1", "url": "https://www.ensembl.org/id/ENSGALP00010032699.1" } ] } }, { "isoform_ac": "A0A8V0ZUV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79/entry#A0A8V0ZUV1-1", "sequence": { "sequence": "MISRAKFSPRPIAAKIGGDAGTSMNSNDYGYGGQKRPLEDGDGSWTSPSSTTHWEGMPSPFKDQPDAKKVAPQNDSFGNQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKMFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVVPGPHGPPGPPGPGAPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQPPNPPDPGKPGTDPNSAAWAAYYAHYYQQQAQPPPAAPPGGPATTQTNGQGDQPNPAPAGQVDYTKAWEEYYKKMGQAVPAPAGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQV", "length": 636, "header": "tr|A0A8V0ZUV1-1|A0A8V0ZP79_CHICK Computationally mapped isoform of Far upstream element-binding protein 1 OS=Gallus gallus OX=9031 GN=FUBP1 PE=1 SV=1 CANONICAL=A0A8V0ZP79-1" }, "locus": { "chromosome": "8", "start_pos": 18600044, "end_pos": 18580709, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054083.1", "url": "https://www.ensembl.org/id/ENSGALT00010054083.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032614.1", "url": "https://www.ensembl.org/id/ENSGALP00010032614.1" } ] } }, { "isoform_ac": "A0A8V0ZUZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79/entry#A0A8V0ZUZ7-1", "sequence": { "sequence": "MNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGNQLPPMHQQQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPDRIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKMFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVVPGPHGPPGPPGPGAPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQPPNPPDPGKPGTDPNSAAWAAYYAHYYQQQAQPPPAAPPGGPATTQTNGQGDQPNPAPAGQVDYTKAWEEYYKKMGQAVPAPAGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLGSAAKKQQC", "length": 608, "header": "tr|A0A8V0ZUZ7-1|A0A8V0ZP79_CHICK Computationally mapped isoform of Far upstream element-binding protein 1 OS=Gallus gallus OX=9031 GN=FUBP1 PE=1 SV=1 CANONICAL=A0A8V0ZP79-1" }, "locus": { "chromosome": "8", "start_pos": 18603497, "end_pos": 18581179, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054136.1", "url": "https://www.ensembl.org/id/ENSGALT00010054136.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032667.1", "url": "https://www.ensembl.org/id/ENSGALP00010032667.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZP79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP79" }, { "id": "SM00322", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00322" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "K Homology", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 208, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPC0-1", "uniprot_ac": "A0A8V0ZPC0", "uniprot_id": "A0A8V0ZPC0_CHICK", "mass": { "chemical_mass": 80313.0, "monoisotopic_mass": 80313.0 }, "refseq": {}, "gene_names": [ { "name": "FIGNL2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ] } ], "protein_names": [ { "name": "Fidgetin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FIGNL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0", "locus": { "chromosome": "34", "start_pos": 232686, "end_pos": 205317, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022248", "url": "https://www.ensembl.org/id/ENSGALG00010022248" } ] } } ], "crossref": [ { "id": "A0A8V0ZPC0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "431296", "url": "https://www.ncbi.nlm.nih.gov/gene/431296", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431296", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431296", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPQPNAA", "url": "https://omabrowser.org/oma/group/CPQPNAA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH86", "url": "https://www.orthodb.org/?gene=A0A8V0ZH86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPC0", "url": "https://www.orthodb.org/?gene=A0A8V0ZPC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPV7", "url": "https://www.orthodb.org/?gene=A0A8V0ZPV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23074", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23074", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23074:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23074:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZH86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVTHKADPPGRPLLGAISAFCPFFTACGGTVKIVEPPGLSKMHWSPEHAQSLNQWPEQHLDVSSTTSSPAHKSDLYPSTRQRFNYAWANDDISALTASNLLKRYAEKYSGVLDAPYERPALSGYGDGAFGPVNGQKGDGEPWPVPHSSDGTYPLTPIHDGLPGAKAVVPPAVPAGSAPLGLTGSPVVSANLTDPIYAGNSCGGAAGSGGLGSSQEYPAGYGSTYLPSGYCGQPSTALAPPHPPALHSSGLLQPTHPSSALVPGYGSSGPVYNYASGSYATQPGYGAIHPPHPSASYLPSGIAAPTPLPAPGPTTRPSVVPAYGYQAAGLASLAVPPLGTEATGTLKRKAFDISGGEDEAEGRYRKYSYEQPKSPYPMSDNGECRGNGFPSASKRPAGSAEEHSSKYGGQAMKSVVSPPYGAGEAPLRPTESFEKFSPPLANGERAAEPGHPFPLRLPPKAPVFSSQPVEEQPKNVDPLVLELVNTKIVERGPPVQWTDIAGQVSIKAAIEEELVWPILRPGAYTGASRLPRTILLFGPRGTGKTLLSRCISTQLGSTLLKLSATALLTTWKAEAEKILQTVFFVAKCRQPSVVLIMEVESLLVAQDGSQAGNLKSQLLSYLDNVATSAEQNVVIIGTTSRPGSMDEASHRRFAKRFYISPPDSIARRQILHHALAQQSSCLSEREMASLVQHTESFSGSELIQLCQHAGATTLHGLPGQIQPTSYKDFEKAFCKVRPAASQKELDLFAEWDKMYGSRH", "length": 759, "header": "tr|A0A8V0ZPC0-1|A0A8V0ZPC0_CHICK Isoform 1 of Fidgetin OS=Gallus gallus OX=9031 GN=FIGNL2 PE=3 SV=1 CANONICAL=A0A8V0ZPC0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZH86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0/entry#A0A8V0ZH86-1", "sequence": { "sequence": "MHWSPEHAQSLNQWPEQHLDVSSTTSSPAHKSDLYPSTRQRFNYAWANDDISALTASNLLKRYAEKYSGVLDAPYERPALSGYGDGAFGPVNGQKGDGEPWPVPHSSDGTYPLTPIHDGLPGAKAVVPPAVPAGSAPLGLTGSPVVSANLTDPIYAGNSCGGAAGSGGLGSSQEYPAGYGSTYLPSGYCGQPSTALAPPHPPALHSSGLLQPTHPSSALVPGYGSSGPVYNYASGSYATQPGYGAIHPPHPSASYLPSGIAAPTPLPAPGPTTRPSVVPAYGYQAAGLASLAVPPLGTEATGTLKRKAFDISGGEDEAEGRYRKYSYEQPKSPYPMSDNGECRGNGFPSASKRPAGSAEEHSSKYGGQAMKSVVSPPYGAGEAPLRPTESFEKFSPPLANGERAAEPGHPFPLRLPPKAPVFSSQPVEEQPKNVDPLVLELVNTKIVERGPPVQWTDIAGQVSIKAAIEEELVWPILRPGAYTGASRLPRTILLFGPRGTGKTLLSRCISTQLGSTLLKLSATALLTTWKAEAEKILQTVFFVAKCRQPSVVLIMEVESLLVAQDGSQAGNLKSQLLSYLDNVATSAEQNVVIIGTTSRPGSMDEASHRRFAKRFYISPPDSIARRQILHHALAQQSSCLSEREMASLVQHTESFSGSELIQLCQHAGATTLHGLPGQIQPTSYKDFEKAFCKVRPAASQKELDLFAEWDKMYGSRH", "length": 717, "header": "tr|A0A8V0ZH86-1|A0A8V0ZPC0_CHICK Computationally mapped isoform of Fidgetin OS=Gallus gallus OX=9031 GN=FIGNL2 PE=3 SV=1 CANONICAL=A0A8V0ZPC0-1" }, "locus": { "chromosome": "34", "start_pos": 230436, "end_pos": 228286, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054149.1", "url": "https://www.ensembl.org/id/ENSGALT00010054149.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032680.1", "url": "https://www.ensembl.org/id/ENSGALP00010032680.1" } ] } }, { "isoform_ac": "A0A8V0ZPC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0/entry#A0A8V0ZPC0-1", "sequence": { "sequence": "MDVTHKADPPGRPLLGAISAFCPFFTACGGTVKIVEPPGLSKMHWSPEHAQSLNQWPEQHLDVSSTTSSPAHKSDLYPSTRQRFNYAWANDDISALTASNLLKRYAEKYSGVLDAPYERPALSGYGDGAFGPVNGQKGDGEPWPVPHSSDGTYPLTPIHDGLPGAKAVVPPAVPAGSAPLGLTGSPVVSANLTDPIYAGNSCGGAAGSGGLGSSQEYPAGYGSTYLPSGYCGQPSTALAPPHPPALHSSGLLQPTHPSSALVPGYGSSGPVYNYASGSYATQPGYGAIHPPHPSASYLPSGIAAPTPLPAPGPTTRPSVVPAYGYQAAGLASLAVPPLGTEATGTLKRKAFDISGGEDEAEGRYRKYSYEQPKSPYPMSDNGECRGNGFPSASKRPAGSAEEHSSKYGGQAMKSVVSPPYGAGEAPLRPTESFEKFSPPLANGERAAEPGHPFPLRLPPKAPVFSSQPVEEQPKNVDPLVLELVNTKIVERGPPVQWTDIAGQVSIKAAIEEELVWPILRPGAYTGASRLPRTILLFGPRGTGKTLLSRCISTQLGSTLLKLSATALLTTWKAEAEKILQTVFFVAKCRQPSVVLIMEVESLLVAQDGSQAGNLKSQLLSYLDNVATSAEQNVVIIGTTSRPGSMDEASHRRFAKRFYISPPDSIARRQILHHALAQQSSCLSEREMASLVQHTESFSGSELIQLCQHAGATTLHGLPGQIQPTSYKDFEKAFCKVRPAASQKELDLFAEWDKMYGSRH", "length": 759, "header": "tr|A0A8V0ZPC0-1|A0A8V0ZPC0_CHICK Isoform 1 of Fidgetin OS=Gallus gallus OX=9031 GN=FIGNL2 PE=3 SV=1 CANONICAL=A0A8V0ZPC0-1" }, "locus": { "chromosome": "34", "start_pos": 230436, "end_pos": 205335, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054138.1", "url": "https://www.ensembl.org/id/ENSGALT00010054138.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032670.1", "url": "https://www.ensembl.org/id/ENSGALP00010032670.1" } ] } }, { "isoform_ac": "A0A8V0ZPV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0/entry#A0A8V0ZPV7-1", "sequence": { "sequence": "MLGCWDASGWSTWMQDAGSWGLSKMHWSPEHAQSLNQWPEQHLDVSSTTSSPAHKSDLYPSTRQRFNYAWANDDISALTASNLLKRYAEKYSGVLDAPYERPALSGYGDGAFGPVNGQKGDGEPWPVPHSSDGTYPLTPIHDGLPGAKAVVPPAVPAGSAPLGLTGSPVVSANLTDPIYAGNSCGGAAGSGGLGSSQEYPAGYGSTYLPSGYCGQPSTALAPPHPPALHSSGLLQPTHPSSALVPGYGSSGPVYNYASGSYATQPGYGAIHPPHPSASYLPSGIAAPTPLPAPGPTTRPSVVPAYGYQAAGLASLAVPPLGTEATGTLKRKAFDISGGEDEAEGRYRKYSYEQPKSPYPMSDNGECRGNGFPSASKRPAGSAEEHSSKYGGQAMKSVVSPPYGAGEAPLRPTESFEKFSPPLANGERAAEPGHPFPLRLPPKAPVFSSQPVEEQPKNVDPLVLELVNTKIVERGPPVQWTDIAGQVSIKAAIEEELVWPILRPGAYTGASRLPRTILLFGPRGTGKTLLSRCISTQLGSTLLKLSATALLTTWKAEAEKILQTVFFVAKCRQPSVVLIMEVESLLVAQDGSQAGNLKSQLLSYLDNVATSAEQNVVIIGTTSRPGSMDEASHRRFAKRFYISPPDSIARRQILHHALAQQSSCLSEREMASLVQHTESFSGSELIQLCQHAGATTLHGLPGQIQPTSYKDFEKAFCKVRPAASQKELDLFAEWDKMYGSRH", "length": 741, "header": "tr|A0A8V0ZPV7-1|A0A8V0ZPV7_CHICK Computationally mapped isoform of Fidgetin OS=Gallus gallus OX=9031 GN=FIGNL2 PE=3 SV=1 CANONICAL=A0A8V0ZPC0-1" }, "locus": { "chromosome": "34", "start_pos": 230436, "end_pos": 215054, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054155.1", "url": "https://www.ensembl.org/id/ENSGALT00010054155.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032686.1", "url": "https://www.ensembl.org/id/ENSGALP00010032686.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 314, "start_aa": "Thr", "end_pos": 314, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr314", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:431296", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431296", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AGW3-1", "protein_name": "Fidgetin-like protein 2", "gene_name": "Fignl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHWTPEHAQPLNQWPEQHLDVSSTTPSPAHKLELPPGGRQRCHYAWAHDDISALTASNLLKRYAEKYSGVLDSPYERPGLGSYGDAAFLNGAKADPEPWPGPEPPYPLASLHEGLPGAKPAGAGGSAGLGGSPVVAGNLTEPLYTGNACGGPSAATEYAAGYGGGYLASGYCAQTSAALAPPPPAALLQPAPPPGYGPSAPLYNYPAAGYAAQPGYGALPPPAAPPAPYLPSGLAAPTPLPAPAPAPPRPAPYGFPGAAEGVSLKRKAVDEGAEARYRKYAYEPAKAPAADGAAYPAADDAECRGNGFRAKPPGTTEDGTGKYGGGGSLKVLGSPAYAPQLEPFDKFAERVPAAHGGFAEPSGEPAKGVDPGTLELVSSKMVDCGPPVQWADVAGQGALKAALEEELLWPLLRPPACPGSARPPRTVLFFGPRGCGKALLGRCLATRLGATLLRLRGAGLATSGAVEGARLLQAAFAAARCRPPAVLLISELDALLPARDDGASLRAPLLTCLDGGCGARADGVLVVGTTSRPAALDEATRRRFALRFYVALPDGAARGQILQRALAQQGCVLSERELAALVQGTQGFSGGELGQLCQQAAAEAGLSGLQRPLSYKEVEAALAKVGPRAPPKELDSLVEWDKMYGSGH", "length": 648 }, "evidence": [ { "id": "A0A8V0ZPC0", "url": "https://omabrowser.org/oma/group/A0A8V0ZPC0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6NMB9-1", "protein_name": "Fidgetin-like protein 2", "gene_name": "FIGNL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHWTPEHAQPLNQWPEQHLDVSSTTPSPAHKLELPPGGRQRCHYAWAHDDISALTASNLLKRYAEKYSGVLDSPYERPALGGYSDASFLNGAKGDPEPWPGPEPPYPLASLHEGLPGTKSGGGGGSGALGGSPVLAGNLPEPLYAGNACGGPSAAPEYAAGYGGGYLAPGYCAQTGAALPPPPPAALLQPPPPPGYGPSAPLYNYPAGGYAAQPGYGALPPPPGPPPAPYLTPGLPAPTPLPAPAPPTAYGFPTAAPGAESGLSLKRKAADEGPEGRYRKYAYEPAKAPVADGASYPAADNGECRGNGFRAKPPGAAEEASGKYGGGVPLKVLGSPVYGPQLEPFEKFPERAPAPRGGFAVPSGETPKGVDPGALELVTSKMVDCGPPVQWADVAGQGALKAALEEELVWPLLRPPAYPGSLRPPRTVLLFGPRGAGKALLGRCLATQLGATLLRLRGATLAAPGAAEGARLLQAAFAAARCRPPSVLLISELEALLPARDDGAAAGGALQVPLLACLDGGCGAGADGVLVVGTTSRPAALDEATRRRFSLRFYVALPDSPARGQILQRALAQQGCALSERELAALVQGTQGFSGGELGQLCQQAAAGAGLPGLQRPLSYKDLEAALAKVGPRASAKELDSFVEWDKMYGSGH", "length": 653 }, "evidence": [ { "id": "A0A8V0ZPC0", "url": "https://omabrowser.org/oma/group/A0A8V0ZPC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E9QEA3-1", "protein_name": "Fidgetin-like protein 2", "gene_name": "fignl2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLSPIVPYSLLKMHWNPEHAQPLSQWPEQHLDVSSTTSSPAHKSELYSSRGRGSYSYAWANDDISALTASNLLKRYAEKYSGMLDSPYERPSVGAYPEPGAFGGLNGGQKSELEPWPLTHSTDGAYSLVPPSSHESLSGPKVVPTSAGPPGSGNVSAVNSNLSDSGYSGSSSCSGPHSSEYPPSYNGTYLSSGYCPQPSSALPPASLHALQPNPTLLPSYTTTAPVYNYPPSTYPHQTGLAPSYTHPTAPYIPSPLPSRPTVVGGSYGYQNSSVGGSEPGGSLKRKAFEMTLDEEDSDSSRYRKYSYDPMKTGGDSPYGVTDKAGNGFGTGSTDPQGFKPSKPSSQSSLEGDEVGKYSGLKPLVSPTYGAAGDYSPPAAMTGENGGAEQGFSQNRSQKRSDPMKSIEPRMLELVSRELQDCSPAMLWTELAGNCHIKAALEEDLLWPVLRPNPAIHPPKTILLFGPQGGGKTTLARSLSSQIGASFYRLSCATLASKLKGEAEQLLLTLFSVATARQPAMVLLSEVEAIEEEGLRQQLQAQLEKIQHNQSNQFLVVCTTRRPDLIKDSLLRCFSKRYHIGLPDGNTRRHVLLQALAPQGCSLSERELSAVLQRSEGFSVWELLQLCQQALASASASASVPLHSLPASLSSPTLQDFENAFCKVRPHSTPKELDTCMEWSKVYSH", "length": 684 }, "evidence": [ { "id": "A0A8V0ZPC0", "url": "https://omabrowser.org/oma/group/A0A8V0ZPC0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MP95-1", "protein_name": "Fidgetin-like protein 2", "gene_name": "FIGNL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHWTPEHAQPLNQWPEQHLDVSSTTPSPAHKLELPPGGRQRCHYAWAHDDISALTASNLLKRYAEKYSGVLDSPYERPTLGGYGDAAFLNGAKGDPEPWPGPETPYPLASLHEGLPGTKSGGGGGSGGLGGSPVLAGNLPEPLYAGNACGGPSAAPEYAAGYGAGYLAPGYCAQTGAALPPPPPAALLQPPPPPGYGPSGSLYNYPAGGYAAQPGYGALPPPPAPPPAPYLTSGLAAPTPLPTPAPPRPSPASYGFQGVTEAGVSLKRKATDEGAEGRYRKYAFEPAKAPAADGTSYPAADNGECRGNGFRVKPPGAAEEASGKYAGGVPLKVLGSPVYGPQLEPFEKFSERAPAPAPRGGFAVPSGEPPKGVDQGALELATSKMVDCGPPVQWADVAGQGALKAALEEELVWPLLRPPTYPGSPRPPRTVLLFGPRGAGKALLGRCLATQLGATLLRLRGGTLVAPGAAEGARLLQAAFAAARCRPPAVLLISELDALLSVRDDGTAAAGALQAPLLACLDGGCGAGADGVLVVGTTSRPAALDEATRRRFALRFYVTLPDGPARGQILQRALAQQGCALSERELAALVQGTQGFSGGELGQLCQQAAAGAGLPGLQRPISYKDMEAALAKVGPRASPKDLDSFVEWDKMYGFGH", "length": 656 }, "evidence": [ { "id": "A0A8V0ZPC0", "url": "https://omabrowser.org/oma/group/A0A8V0ZPC0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "J3QK54-1", "protein_name": "Fidgetin-like protein 2", "gene_name": "Fignl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHWTPEHAQPLNQWPEQHLDVSSTTPSPAHKLELPPGGRQRCHYAWAHDDISALTASNLLKRYAEKYSGVLDYERPGLGSYGDAAFLNGAKGDPEPWPGPEPPYPLASLHEGLPGAKAAGAGGSAGLGGSPVVAGNLTEPLYTGNACGGPSAATEYAAGYGGGYLASGYCAQTSAALAPPPPPALLQPAPPPGYGPSAPLYNYPAAGYAAQPGYGALPPPAAPPAPYLPSGLAAPTPLPAPAPPRPAPYGFPAAAEGVSLKRKAVDEGAEARYRKYAYEPAKAPAADGASYPAADDTECRGNGFRSKPPGATEDGTGKYGGGGPLKVLGSPAYAPQLEPFDKFPERVPAAHGGFAEPSGEPAKGVDPGALELVSSKMVDCGPPVQWADVAGQGALKAALEEELLWPLLRPPACPGSALPPRTVLFFGPRGCGKALLGRCLATRLGATLLRLRGAGLAASGAVEGARLLQAAFAAARCRPPAVLLISELDALLPARDDGASLRAPLLTCLDGSCGARADGVLVVGTTSRPAALDEATRRRFALRFYVALPDGAARGQILQRALAQQGCALNERELAALVQGTQGFSGGELGQLCQQAAAEAGISGLQRPLSYKDVEAALAKVGSRAPSKELDSLVEWDKMYGSGH", "length": 644 }, "evidence": [ { "id": "A0A8V0ZPC0", "url": "https://omabrowser.org/oma/group/A0A8V0ZPC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" }, { "name": "microtubule severing ATPase activity", "id": "GO:0008568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008568", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" }, { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" }, { "name": "negative regulation of wound healing, spreading of epidermal cells", "id": "GO:1903690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903690", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" }, { "name": "microtubule severing", "id": "GO:0051013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" }, { "name": "negative regulation of axon regeneration", "id": "GO:0048681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048681", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC0" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 530, "end_pos": 663, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 314 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPL1-1", "uniprot_ac": "A0A8V0ZPL1", "uniprot_id": "A0A8V0ZPL1_CHICK", "mass": { "chemical_mass": 73207.0, "monoisotopic_mass": 73207.0 }, "refseq": { "ac": "NP_001008459", "name": "BTB/POZ domain-containing protein 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008459" }, "gene_names": [ { "name": "BTBD9", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1" } ] }, { "name": "BTBD9", "type": "synonym", "evidence": [ { "id": "NP_001008459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008459" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein 9", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1/entry#names_and_taxonomy" } ] }, { "name": "BTB (POZ) domain containing 9", "type": "synonym", "evidence": [ { "id": "NP_001008459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008459" } ] }, { "name": "BTB/POZ domain-containing protein 9", "type": "synonym", "evidence": [ { "id": "NP_001008459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008459" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720188.1, SRR13267656.22899.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000063.1. On Nov 24, 2021 this sequence version replaced NP_001008459.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008459", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008459" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BTBD9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1", "locus": { "chromosome": "3", "start_pos": 29372804, "end_pos": 29198726, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021236", "url": "https://www.ensembl.org/id/ENSGALG00010021236" } ] } } ], "crossref": [ { "id": "A0A8V0ZPL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14822", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14822", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18287", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18287", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421429", "url": "https://www.ncbi.nlm.nih.gov/gene/421429", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421429", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421429", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LCMINHI", "url": "https://omabrowser.org/oma/group/LCMINHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH97", "url": "https://www.orthodb.org/?gene=A0A8V0ZH97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPL1", "url": "https://www.orthodb.org/?gene=A0A8V0ZPL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPL5", "url": "https://www.orthodb.org/?gene=A0A8V0ZPL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPL9", "url": "https://www.orthodb.org/?gene=A0A8V0ZPL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46306", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46306", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46306:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46306:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001008459", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008459", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH97", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKNPNFQEVGHLPTGYIHCRPSESFTGYQYHHPSKMSNSHPLRPYTAVGEIDHVHILSEHIGALMNGEEYSDVTFIVEKKRFPAHRVILAARCHYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLMKYIYTGRATLRDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKAALLSIVLRDSFAAPEKDIFQALMNWCKHNPKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKIRSESRDMDLNYRGMLIPGENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYYIEVSMDELDWIRVIDHSKYLCRSWQNLYFPARVCRYIRIVGTHNTVNKVFHIVAFECMFTNKTFALEKGLIVPTENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYIEVSTNQQQWTMVADRTKVSCKSWQTITFDKQPASFIRIVGTQNTANEVFHCVHFECPAQSATHKDEGCKEVATTEVGTGEQQLVSRPVRAASTSSLHSPPGSTLRSHAHQP", "length": 647, "header": "tr|A0A8V0ZPL1-1|A0A8V0ZPL1_CHICK Isoform 1 of BTB/POZ domain-containing protein 9 OS=Gallus gallus OX=9031 GN=BTBD9 PE=4 SV=1 CANONICAL=A0A8V0ZPL1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZH97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1/entry#A0A8V0ZH97-1", "sequence": { "sequence": "MAKNPNFQEVGHLPTGYIHCRPSESFTGYQYHHPSKMSNSHPLRPYTAVGEIDHVHILSEHIGALMNGEEYSDVTFIVEKKRFPAHRVILAARCHYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLMKYIYTGRATLRDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKAALLSIVLRDSFAAPEKDIFQALMNWCKHNPKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKIRSESRDMDLNYRGMLIPGENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYYIEVSMDELDWIRVIDHSKYLCRSWQNLYFPARVCRYIRIVGTHNTVNKVFHIVAFECMFTNKTFALEKGLIVPTENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYIEVSTNQQQWTMVADRTKVSCKSWQTITFDKQPASFIRIVGTQNTANEVPETA", "length": 588, "header": "tr|A0A8V0ZH97-1|A0A8V0ZPL1_CHICK Computationally mapped isoform of BTB/POZ domain-containing protein 9 OS=Gallus gallus OX=9031 GN=BTBD9 PE=4 SV=1 CANONICAL=A0A8V0ZPL1-1" }, "locus": { "chromosome": "3", "start_pos": 29352800, "end_pos": 29200588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051478.1", "url": "https://www.ensembl.org/id/ENSGALT00010051478.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030669.1", "url": "https://www.ensembl.org/id/ENSGALP00010030669.1" } ] } }, { "isoform_ac": "A0A8V0ZPL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1/entry#A0A8V0ZPL1-1", "sequence": { "sequence": "MAKNPNFQEVGHLPTGYIHCRPSESFTGYQYHHPSKMSNSHPLRPYTAVGEIDHVHILSEHIGALMNGEEYSDVTFIVEKKRFPAHRVILAARCHYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLMKYIYTGRATLRDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKAALLSIVLRDSFAAPEKDIFQALMNWCKHNPKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKIRSESRDMDLNYRGMLIPGENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYYIEVSMDELDWIRVIDHSKYLCRSWQNLYFPARVCRYIRIVGTHNTVNKVFHIVAFECMFTNKTFALEKGLIVPTENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYIEVSTNQQQWTMVADRTKVSCKSWQTITFDKQPASFIRIVGTQNTANEVFHCVHFECPAQSATHKDEGCKEVATTEVGTGEQQLVSRPVRAASTSSLHSPPGSTLRSHAHQP", "length": 647, "header": "tr|A0A8V0ZPL1-1|A0A8V0ZPL1_CHICK Isoform 1 of BTB/POZ domain-containing protein 9 OS=Gallus gallus OX=9031 GN=BTBD9 PE=4 SV=1 CANONICAL=A0A8V0ZPL1-1" }, "locus": { "chromosome": "3", "start_pos": 29308206, "end_pos": 29200588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051472.1", "url": "https://www.ensembl.org/id/ENSGALT00010051472.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030663.1", "url": "https://www.ensembl.org/id/ENSGALP00010030663.1" } ] } }, { "isoform_ac": "A0A8V0ZPL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1/entry#A0A8V0ZPL5-1", "sequence": { "sequence": "MAKNPNFQEVGHLPTGYIHCRPSESFTGYQYHHPSKMSNSHPLRPYTAVGEIDHVHILSEHIGALMNGEEYSDVTFIVEKKRFPAHRVILAARCHYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLMKYIYTGRATLRDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKAALLSIVLRDSFAAPEKDIFQALMNWCKHNPKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKIRSESRDMDLNYRGMLIPGENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYYIEVSMDELDWIRVIDHSKYLCRSWQNLYFPARVCRYIRIVGTHNTVNKVFHIVAFECMFTNKTFALEKGLIVPTENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYIEVSTNQQQWTMVADRTKVSCKSWQTITFDKQPASFIRIVGTQNTANEVFHCVHFECPAQSATHKDEGCKEVATTEV", "length": 612, "header": "tr|A0A8V0ZPL5-1|A0A8V0ZPL5_CHICK Computationally mapped isoform of BTB/POZ domain-containing protein 9 OS=Gallus gallus OX=9031 GN=BTBD9 PE=4 SV=1 CANONICAL=A0A8V0ZPL1-1" }, "locus": { "chromosome": "3", "start_pos": 29313525, "end_pos": 29200588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051477.1", "url": "https://www.ensembl.org/id/ENSGALT00010051477.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030668.1", "url": "https://www.ensembl.org/id/ENSGALP00010030668.1" } ] } }, { "isoform_ac": "A0A8V0ZPL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1/entry#A0A8V0ZPL9-1", "sequence": { "sequence": "MAKNPNFQEVGHLPTGYIHCRPSESFTGYQYHHPSKMSNSHPLRPYTAVGEIDHVHILSEHIGALMNGEEYSDVTFIVEKKRFPAHRVILAARCHYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLMKYIYTGRATLRDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKAALLSIVLRDSFAAPEKDIFQALMNWCKHNPKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKIRSESRDMDLNYRGMLIPGENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYYIEVSMDELDWIRVIDHSKYLCRSWQNLYFPARVCRYIRIVGTHNTVNKVFHIVAFECMFTNKTFALEKGLIVPTENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYIEVSTNQQQWTMVADRTKVSCKSWQTITFDKQPASFIRIVGTQNTANEMEYELYLPMQILWQVSPCRDTIKQLQTRPESESASFQYMTTGRR", "length": 627, "header": "tr|A0A8V0ZPL9-1|A0A8V0ZPL9_CHICK Computationally mapped isoform of BTB/POZ domain-containing protein 9 OS=Gallus gallus OX=9031 GN=BTBD9 PE=4 SV=1 CANONICAL=A0A8V0ZPL1-1" }, "locus": { "chromosome": "3", "start_pos": 29372803, "end_pos": 29200588, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051482.1", "url": "https://www.ensembl.org/id/ENSGALT00010051482.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030673.1", "url": "https://www.ensembl.org/id/ENSGALP00010030673.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421429", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421429", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B5I7-1", "protein_name": "BTB/POZ domain-containing protein 9", "gene_name": "BTBD9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLSIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDWIRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGLIVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRVLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTHNTANEVFHCVHFECPEQQSSQKEENSEELGTGDTSPASHQLDPHALQAPSGNALPASPGAPSRSPNRQHR", "length": 612 }, "evidence": [ { "id": "A0A8V0ZPL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZPL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5PQR3-1", "protein_name": "BTB/POZ domain-containing protein 9", "gene_name": "Btbd9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLRYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLASDGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNAKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRLLLWDRDSRSYSYFIEVSMDELDWIRVIDHSHYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKAFTLEKGLIAPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTHNTANEVFHCVHFECPEQQSTQKEDSSEEPGTGDLSTPSQQLDPHAPRAPSASSLPPSPGPNLHSPNQQNQ", "length": 612 }, "evidence": [ { "id": "A0A8V0ZPL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZPL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C726-1", "protein_name": "BTB/POZ domain-containing protein 9", "gene_name": "Btbd9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKHFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLRYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLASDGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNAKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRLLLWDRDSRSYSYFIEVSMDELDWIRVIDHSHYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKAFTLEKGLIVPLENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYIIGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTHNTANEVFHCVHFECPEQQSNQKEDSSEEPGTGDPSTPNQQLDPHAPRAPSASSLPPSPGPNSRSPNQQNQ", "length": 612 }, "evidence": [ { "id": "A0A8V0ZPL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZPL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96Q07-1", "protein_name": "BTB/POZ domain-containing protein 9", "gene_name": "BTBD9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDWVRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGLIVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTHNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSPGSNSRSPNRQHQ", "length": 612 }, "evidence": [ { "id": "A0A8V0ZPL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZPL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W2S3-1", "protein_name": "BTB/POZ domain-containing protein 9", "gene_name": "BTBD9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSQGHHKMSGGGKKGAMEQDYTDVVDLGDRFSADMARLCMNEQYADVEFIVEEERIPAHRVILAARSEYFRALLYGGMAETTQRQIPLEVPLEAFKVLLRYIYSGTLLLSTLDEDSTIDVLGMANQYGFQDLEMAISNYLRQYLALDNVCMILDAARLYNLEELTEVCLMFMDRNAGDLLLHNSFNTLSKESLEEVLRRDCFFAPEVQIFLAVWKWSRFNSNVDFKSVVSYVRLPLMNLEHLLQVVRPSGILDPDKILDAIDERSTSKALPYRAALWPEENVAAETFLSRCIQGECRDALLDGDVTTYDMENGYTRHCITDSKDAGIVVELGTFCMINHIRMLLWDRDSRAYSYYVEVSGDQQHWDRVVDYSDYHCRSWQYLYFEARPVRFIRLVGTQNTVNRVFHVVGLEAMHTAKVPRLVNHFVAPKTNVATVEMSAIVTDGVSRTRNALINGDYVRYDWDSGYTCHQLGSGEIVVRLGQPYYLGSMRLLLWDCDDRTYSFYIEISTNRKEWQMVVDRRNDRTRSWQNFHFTPRPVVYIRIVGTRNTANEIFHCVHLECPTQDKNYLKKIADMEKEREKREKEKKTAKTDDDNIASTSGSSLASGHAESPSTSSSSSQSVLRSIHWPPQTREVAVAPLTPPALSPPGTPALPAPLTPATSSPHNNHEQNQPSNISADASHHTSPSSRSNPSPSLSRSRSQSAELEPVPPLVELDTRETL", "length": 722 }, "evidence": [ { "id": "A0A8V0ZPL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZPL1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "adult locomotory behavior", "id": "GO:0008344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008344", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1" } ], "pmid": "" }, { "name": "circadian behavior", "id": "GO:0048512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL1" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 140, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 447, "end_pos": 449 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPX2-1", "uniprot_ac": "A0A8V0ZPX2", "uniprot_id": "A0A8V0ZPX2_CHICK", "mass": { "chemical_mass": 144853.0, "monoisotopic_mass": 144853.0 }, "refseq": {}, "gene_names": [ { "name": "ALPK3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ], "protein_names": [ { "name": "Alpha-protein kinase 3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Involved in cardiomyocyte differentiation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZHB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB0#function" }, { "database": "UniProtKB", "id": "ARBA00053245", "url": "https://www.uniprot.org/uniprotkb/ARBA00053245#function" }, { "database": "UniProtKB", "id": "A0A8V0ZHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZPX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ALPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2", "locus": { "chromosome": "10", "start_pos": 916404, "end_pos": 935078, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022253", "url": "https://www.ensembl.org/id/ENSGALG00010022253" } ] } } ], "crossref": [ { "id": "cd16973", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16973", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004166", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004166", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHB0", "url": "https://www.orthodb.org/?gene=A0A8V0ZHB0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHB5", "url": "https://www.orthodb.org/?gene=A0A8V0ZHB5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPX2", "url": "https://www.orthodb.org/?gene=A0A8V0ZPX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47091", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47091", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47091:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47091:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02816", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02816", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZHB0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHB5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLESSRSTFCAIISQLTEETQPLFETTIKSRSVSEDSDAKFTCIVTGYPQPEVTWYKDNEEMDRYCGLPKYQIFHHGNRHTLQLYKCREEDAGIYQASARNTKGIVSCSGVLEVGTMTEFKIHQKWFAKIKRKAEEKLREIEQSKKRGKENVEVESLQGMSPDRLQRKRRLARDLNLRSGASLWEKEDAAKVHVTDSKSRLREDVADSKEQSVNAMTGLPSKLITPLKAEVTTNGDASLESVEENGNGFLAYIYETVEDLVSKPLAKDSAAKKKKKVEDAPAAKQEVLKREESGRDRVKPSTNPSNIKHPVSGPNTDSSQQADKLEELRKETPVSQETRGTGKRTNPRLRFQDTSKPPAPSADHAQTSREQPASRAQAEGHSHALEGRETQGLSNQEVKSQGTKEPLPKKLSPPELGEDTPHEKSTHQAAVKDEKSKEEGVGPSGSKPCAEAGGSSVAELSPEKAGTPLELQETETPAPASVCVAEEKLIPTAAVGTLVVQEAPPAACSSQEMKTAAAEAPSGIQLLPSVSKDTETKKADGAAPQEMFPTSTSGKADAKPVSVVPQRKEGGMQMATAPSQQPAAPLGIFERGAEVQPQAPLILPSPERPQEMTLEEKMQHKNLVSSLKNYLLLLLQLSDSSKDATKEDAEPRGEEPSAAEEAPLPAIGIAGLSPRTSRRVFEKVQNNQLFQTAENLPLTPRTSRRITGMINEEFITSKEMLACRPVPPKRRTKMAPEAEGPLQLSVPSIVVGNVPAAAVGQPPHSVPNLPPVISEKESPADPLAVLPCATPEELASGARRKIYLPKTKQAGEEEEVSPESQGHSRSPTVSPRQSRKSAALLQTPALAPSPPTEKRSPTLTKKMATLEVPKLYEEPTGDSSRDHEVPEDAKPEEQPAESKKASNPFKAPQVIRKIRAEQFSDASGNLKLWCQFFNILSDSKLMWYKDELPVAEAQRSAGDEGQAALAIVQASQKDCGVYRCVISNEYGMDSTDFLLSPEVLSGFILREEIEVGEEIEMTPMVFAKGLADAGYWGDKFFGRVMSEDMELGAGFLRKACRARAIYGLEPVFESGCTCIIKVHNFIVFGTKNENSLIEKNYDITIQECKIQNSSREYCKIFAAEARAVPGFGAVPEIVPLYLIYRPANNVPYATMEEDLGGPCEQYCVTERDGSLVARGTSEIVLKCCTFQHWVYQWTNGNILVTDMEGVGWKMTNVRIATNFKGYQGLKESCFPSLLEQFAATHQCNHYCDMLGLKTLEPVKPKGSKSPSMGRKSAQSSPQLQKKGTTSPQGTRKTTVSPRSARRMAEAAEAQAQAGGTPAFGCCPSS", "length": 1326, "header": "tr|A0A8V0ZPX2-1|A0A8V0ZPX2_CHICK Isoform 1 of Alpha-protein kinase 3 OS=Gallus gallus OX=9031 GN=ALPK3 PE=3 SV=1 CANONICAL=A0A8V0ZPX2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2/entry#A0A8V0ZHB0-1", "sequence": { "sequence": "MLLESSRSTFCAIISQLTEETQPLFETTIKSRSVSEDSDAKFTCIVTGYPQPEVTWYKDNEEMDRYCGLPKYQIFHHGNRHTLQLYKCREEDAGIYQASARNTKGIVSCSGVLEVGTMTEFKIHQKWFAKIKRKAEEKLREIEQSKKRGKENVEVESLQGMSPDRLQRKRRLARDLNLRSGASLWEKEDAAKVHVTDSKSRLREDVADSKEQSVNAMTGLPSKLITPLKAEVTTNGDASLESVEENGNGFLAYIYETVEDLVSKPLAKDSAAKKKKKVEDAPAAKQEVLKREESGRDRVKPSTNPSSQQADKLEELRKETPVSQETRGTGKRTNPRLRFQDTSKPPAPSADHAQTSREQPASRAQAEGHSHALEGRETQGLSNQEVKSQGTKEPLPKKLSPPELGEDTPHEKSTHQAAVKDEKSKEEGVGPSGSKPCAEAGGSSVAELSPEKAGTPLELQETETPAPASVCVAEEKLIPTAAVGTLVVQEAPPAACSSQEMKTAAAEAPSGIQLLPSVSKDTETKKADGAAPQEMFPTSTSGKADAKPVSVVPQRKEGGMQMATAPSQQPAAPLGIFERGAEVQPQAPLILPSPERPQEMTLEEKMHSKDATKEDAEPRGEEPSAAEEAPLPAIGIAGLSPRTSRRVFEKVQNNQLFQTAENLPLTPRTSRRITGMINEEFITSKEMLACRPVPPKRRTKMAPEAEGPLQLSVPSIVVGNVPAAAVGQPPHSVPNLPPVISEKESPADPLAVLPCATPEELASGARRKIYLPKTKQAGEEEEVSPESQGHSRSPTVSPRQSRKSAALLQTPALAPSPPTEKRSPTLTKKMATLEVPKLYEEPTGDSSRDHEVPEDAKPEEQPAESKKASNPFKAPQVIRKIRAEQFSDASGNLKLWCQFFNILSDSKLMWYKDELPVAEAQRSAGDEGQAALAIVQASQKDCGVYRCVISNEYGMDSTDFLLSPEVLSGFILREEIEVGEEIEMTPMVFAKGLADAGYWGDKFFGRVMSEDMELGAGFLRKACRARAIYGLEPVFESGCTCIIKVHNFIVFGTKNENSLIEKNYDITIQECKIQNSSREYCKIFAAEARAVPGFGAVPEIVPLYLIYRPANNVPYATMEEDLGGPCEQYCVTERDGSLVARGTSEIVLKCCTFQHWVYQWTNGNILVTDMEGVGWKMTNVRIATNFKGYQGLKESCFPSLLEQFAATHQCNHYCDMLGLKTLEPVKPKGSKSPSMGRKSAQSSPQLQKKGTTSPQGTRKTTVSPRSARRMAEAAEAQAASKIRPGEASGSACPQ", "length": 1294, "header": "tr|A0A8V0ZHB0-1|A0A8V0ZPX2_CHICK Computationally mapped isoform of Alpha-protein kinase 3 OS=Gallus gallus OX=9031 GN=ALPK3 PE=3 SV=1 CANONICAL=A0A8V0ZPX2-1" }, "locus": { "chromosome": "10", "start_pos": 934516, "end_pos": 917575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054185.1", "url": "https://www.ensembl.org/id/ENSGALT00010054185.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032710.1", "url": "https://www.ensembl.org/id/ENSGALP00010032710.1" } ] } }, { "isoform_ac": "A0A8V0ZHB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2/entry#A0A8V0ZHB5-1", "sequence": { "sequence": "MVSWSTYCECLLAAVRGEASIMLFLSTERSTFCAIISQLTEETQPLFETTIKSRSVSEDSDAKFTCIVTGYPQPEVTWYKDNEEMDRYCGLPKYQIFHHGNRHTLQLYKCREEDAGIYQASARNTKGIVSCSGVLEVGTMTEFKIHQKWFAKIKRKAEEKLREIEQSKKRGKENVEVESLQGMSPDRLQRKRRLARDLNLRSGASLWEKEDAAKVHVTDSKSRLREDVADSKEQSVNAMTGLPSKLITPLKAEVTTNGDASLESVEENGNGFLAYIYETVEDLVSKPLAKDSAAKKKKKVEDAPAANKDTETKKADGAAPQEMFPTSTSGKADAKPVSVVPQRKEGGMQMATAPSQQPAAPLGIFERGAEVQPQAPLILPSPERPQEMTLEEKMQHKNLVSSLKNYLLLLLQLSDSSKDATKEDAEPRGEEPSAAEEAPLPAIGIAGLSPRTSRRVFEKVQNNQLFQTAENLPLTPRTSRRITGMINEEFITSKEMLACRPGPLQLSVPSIVVGNVPAAAVGQPPHSVPNLPPVISEKESPADPLAVLPCATPEELASGARRKIYLPKTKQAGEEEEVSPESQGHSRSPTVSPRQSRKSAALLQTPALAPSPPTEKRSPTLTKKMATLEVPKLYEEPTGDSSRDHEVPEDAKPEEQPAESKKASNPFKAPQVIRKIRAEQFSDASGNLKLWCQFFNILSDSKLMWYKDELPVAEAQRSAGDEGQAALAIVQASQKDCGVYRCVISNEYGMDSTDFLLSPEVLSGFILREEIEVGEEIEMTPMVFAKGLADAGYWGDKFFGRVMSEDMELGAGFLRKACRARAIYGLEPVFESGCTCIIKVHNFIVFGTKNENSLIEKNYDITIQECKIQNSSREYCKIFAAEARAVPGFGAVPEIVPLYLIYRPANNVPYATMEEDLGGPCEQYCVTERDGSLVARGTSEIVLKCCTFQHWVYQWTNGNILVTDMEGVGWKMTNVRIATNFKGYQGLKESCFPSLLEQFAATHQCNHYCDMLGLKTLEPVKPKGSKSPSMGRKSAQSSPQLQKKGTTSPQGTRKTTVSPRSARRMAEAAEAQAASKIRPGEASGSACPQ", "length": 1089, "header": "tr|A0A8V0ZHB5-1|A0A8V0ZPX2_CHICK Computationally mapped isoform of Alpha-protein kinase 3 OS=Gallus gallus OX=9031 GN=ALPK3 PE=3 SV=1 CANONICAL=A0A8V0ZPX2-1" }, "locus": { "chromosome": "10", "start_pos": 935078, "end_pos": 917575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054192.1", "url": "https://www.ensembl.org/id/ENSGALT00010054192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032715.1", "url": "https://www.ensembl.org/id/ENSGALP00010032715.1" } ] } }, { "isoform_ac": "A0A8V0ZPX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2/entry#A0A8V0ZPX2-1", "sequence": { "sequence": "MLLESSRSTFCAIISQLTEETQPLFETTIKSRSVSEDSDAKFTCIVTGYPQPEVTWYKDNEEMDRYCGLPKYQIFHHGNRHTLQLYKCREEDAGIYQASARNTKGIVSCSGVLEVGTMTEFKIHQKWFAKIKRKAEEKLREIEQSKKRGKENVEVESLQGMSPDRLQRKRRLARDLNLRSGASLWEKEDAAKVHVTDSKSRLREDVADSKEQSVNAMTGLPSKLITPLKAEVTTNGDASLESVEENGNGFLAYIYETVEDLVSKPLAKDSAAKKKKKVEDAPAAKQEVLKREESGRDRVKPSTNPSNIKHPVSGPNTDSSQQADKLEELRKETPVSQETRGTGKRTNPRLRFQDTSKPPAPSADHAQTSREQPASRAQAEGHSHALEGRETQGLSNQEVKSQGTKEPLPKKLSPPELGEDTPHEKSTHQAAVKDEKSKEEGVGPSGSKPCAEAGGSSVAELSPEKAGTPLELQETETPAPASVCVAEEKLIPTAAVGTLVVQEAPPAACSSQEMKTAAAEAPSGIQLLPSVSKDTETKKADGAAPQEMFPTSTSGKADAKPVSVVPQRKEGGMQMATAPSQQPAAPLGIFERGAEVQPQAPLILPSPERPQEMTLEEKMQHKNLVSSLKNYLLLLLQLSDSSKDATKEDAEPRGEEPSAAEEAPLPAIGIAGLSPRTSRRVFEKVQNNQLFQTAENLPLTPRTSRRITGMINEEFITSKEMLACRPVPPKRRTKMAPEAEGPLQLSVPSIVVGNVPAAAVGQPPHSVPNLPPVISEKESPADPLAVLPCATPEELASGARRKIYLPKTKQAGEEEEVSPESQGHSRSPTVSPRQSRKSAALLQTPALAPSPPTEKRSPTLTKKMATLEVPKLYEEPTGDSSRDHEVPEDAKPEEQPAESKKASNPFKAPQVIRKIRAEQFSDASGNLKLWCQFFNILSDSKLMWYKDELPVAEAQRSAGDEGQAALAIVQASQKDCGVYRCVISNEYGMDSTDFLLSPEVLSGFILREEIEVGEEIEMTPMVFAKGLADAGYWGDKFFGRVMSEDMELGAGFLRKACRARAIYGLEPVFESGCTCIIKVHNFIVFGTKNENSLIEKNYDITIQECKIQNSSREYCKIFAAEARAVPGFGAVPEIVPLYLIYRPANNVPYATMEEDLGGPCEQYCVTERDGSLVARGTSEIVLKCCTFQHWVYQWTNGNILVTDMEGVGWKMTNVRIATNFKGYQGLKESCFPSLLEQFAATHQCNHYCDMLGLKTLEPVKPKGSKSPSMGRKSAQSSPQLQKKGTTSPQGTRKTTVSPRSARRMAEAAEAQAQAGGTPAFGCCPSS", "length": 1326, "header": "tr|A0A8V0ZPX2-1|A0A8V0ZPX2_CHICK Isoform 1 of Alpha-protein kinase 3 OS=Gallus gallus OX=9031 GN=ALPK3 PE=3 SV=1 CANONICAL=A0A8V0ZPX2-1" }, "locus": { "chromosome": "10", "start_pos": 934516, "end_pos": 917492, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054174.1", "url": "https://www.ensembl.org/id/ENSGALT00010054174.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032703.1", "url": "https://www.ensembl.org/id/ENSGALP00010032703.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cardiac muscle cell development", "id": "GO:0055013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPX2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1109, "end_pos": 1111, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", 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] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNF3-1", "uniprot_ac": "A0A8V0ZNF3", "uniprot_id": "A0A8V0ZNF3_CHICK", "mass": { "chemical_mass": 34604.0, "monoisotopic_mass": 34604.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Fibrous sheath-interacting protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLASKSDACVKHWRARSEDVCGWLIPGEGYTPEPMEFHHLNEIDRKLQILLSNGDFSAISSSCSNPPSQIYQESLVYANRSLEVVPGEKVLRDNREYRDQQNRLKEIDHQLKSLERNSIEDKTGLSEEQLKTLLEECMQPQRTISNVTMPKSQESLSCGLSPPCYTSQVSILHSTSTLSKMLVEDHIVGMLTALEKAGLEDKSLCVNAESEIPSYYISKALADSHLSKDSLAQTEEPDDLEVLQKMRDKSITEGYFMSRALNTERLKKPSFLGEPLYCISMNNEPSTGPDILSIPLQTKGDDMKIES", "length": 308, "header": "tr|A0A8V0ZNF3-1|A0A8V0ZNF3_CHICK Isoform 1 of Fibrous sheath-interacting protein 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZNF3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF3/entry#A0A8V0ZHC8-1", "sequence": { "sequence": "MEDVCGWLIPGEGYTPEPMEFHHLNEIDRKLQILLSNGDFSAISSSCSNPPSQIYQESLVYANRSLEVVPGEKVLRDNREYRDQQNRLKEIDHQLKSLERNSIEDKTGLSEEQLKTLLEECMQPQRTISNVTMPKSQESLSCGLSPPCYTSQVSILHSTSTLSKMLVEDHIVGMLTALEKAGLEDKSLCVNAESEIPSYYISKALADSHLSKDSLAQTEEPDDLEVLQKMRDKSITEGYFMSRALNTERLKKPSFLGEPLYCISMNNEPSTGPDILSIPLQTKGDDMKIES", "length": 291, "header": "tr|A0A8V0ZHC8-1|A0A8V0ZNF3_CHICK Computationally mapped isoform of Fibrous sheath-interacting protein 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZNF3-1" }, "locus": { "chromosome": "5", "start_pos": 29113783, "end_pos": 29056395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051033.1", "url": "https://www.ensembl.org/id/ENSGALT00010051033.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030224.1", "url": "https://www.ensembl.org/id/ENSGALP00010030224.1" } ] } }, { "isoform_ac": "A0A8V0ZHF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF3/entry#A0A8V0ZHF0-1", "sequence": { "sequence": "MEFHHLNEIDRKLQILLSNGDFSAISSSCSNPPSQIYQESLVYANRSLEVVPGEKVLRDNREYRDQQNRLKEIDHQLKSLERNSIEDKTGLSEEQLKTLLEECMQPQRTISNVTMPKSQESLSCGLSPPCYTSQVSILHSTSTLSKMLVEDHIVGMLTALEKAGLEDKSLCVNAESEIPSYYISKALADSHLSKDSLAQTEEPDDLEVLQKMRDKSITEGYFMSRALNTERLKKPSFLGEPLYCISMNNEPSTGPDILSIPLQTKGDDMKIES", "length": 273, "header": "tr|A0A8V0ZHF0-1|A0A8V0ZNF3_CHICK Computationally mapped isoform of Fibrous sheath-interacting protein 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZNF3-1" }, "locus": { "chromosome": "5", "start_pos": 29113783, "end_pos": 29061525, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051037.1", "url": "https://www.ensembl.org/id/ENSGALT00010051037.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030228.1", "url": "https://www.ensembl.org/id/ENSGALP00010030228.1" } ] } }, { "isoform_ac": "A0A8V0ZNF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF3/entry#A0A8V0ZNF3-1", "sequence": { "sequence": "MLLASKSDACVKHWRARSEDVCGWLIPGEGYTPEPMEFHHLNEIDRKLQILLSNGDFSAISSSCSNPPSQIYQESLVYANRSLEVVPGEKVLRDNREYRDQQNRLKEIDHQLKSLERNSIEDKTGLSEEQLKTLLEECMQPQRTISNVTMPKSQESLSCGLSPPCYTSQVSILHSTSTLSKMLVEDHIVGMLTALEKAGLEDKSLCVNAESEIPSYYISKALADSHLSKDSLAQTEEPDDLEVLQKMRDKSITEGYFMSRALNTERLKKPSFLGEPLYCISMNNEPSTGPDILSIPLQTKGDDMKIES", "length": 308, "header": "tr|A0A8V0ZNF3-1|A0A8V0ZNF3_CHICK Isoform 1 of Fibrous sheath-interacting protein 1 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZNF3-1" }, "locus": { "chromosome": "5", "start_pos": 29113783, "end_pos": 29060698, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051035.1", "url": "https://www.ensembl.org/id/ENSGALT00010051035.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030226.1", "url": "https://www.ensembl.org/id/ENSGALP00010030226.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], 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"https://www.ebi.ac.uk/interpro/entry/IPR013766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHF9", "url": "https://www.orthodb.org/?gene=A0A8V0ZHF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPK3", "url": "https://www.orthodb.org/?gene=A0A8V0ZPK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ14", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44340:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44340:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "21064", "url": "https://www.rhea-db.org/rhea/21064", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZHF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFLLSKGDYPTSFRRSLLVVLVCVMVLVCTDQDYYSLLGVSKEASSREIRQAFKKLALKLHPDKNQNDPNAHDNFLKINRAYEVLKDEDLRKKYDKYGEKGLEDQQQGGRYESWHYYRYDFGIYDDDPEIITLDRGEFDAAVNSGELWFVNFYSPRCSHCHDLAPTWREFAKEMDGVIRIGAVNCGDNRMLCRIKGINSYPSLYVFKTGMQPVKYYGDRSKESLKNFAMQYVTSTVTELWAGNFVNAIETSFASGLGWLITFCAERGDCLSYQTRLKLAGMLEGLANVGWMDCGTQGELCDNLDISSSTTAYFPPGATINNKEKGGVLFLNSLDAREIYQEVMKHLPDFEIISATSLEDHLAHHRWLLFFQFGENDKSSVQEFKKLKFLLKDEHIQVGKFDCLSSPTICNKLYVYQPCLAVFKGKGIEDYEIHHGKNDFLSTLFFEGKKILYDIVAFAKESVNSHVITLGPQNFPGKEKEPWLVDFFAPWCPPCRALLPELRKASKHLYGQLKFGTLDCTVHEGLCNMHNIRAYPTTVVFNQSDVHEYEGHHSAEQILEFIEDLRNPSVISLTPETFVELVERRKREEIWMVDFYAPWCGPCQALMPEWKKMARMLNGLISVGSVDCQKFYSFCHQENVRGYPEIRLFPQKSSTAHQYYSYNGWHRDSYSLRGWALGYLPRVSIDLTPQSFTEKVLNGKDHWVIDFYAPWCGPCQNFAPEFEILARAVKGKVKAGKVDCQAYGQTCQSADIRAYPTVKFYPYQGTKKSVLGEYIDSRDAKGIADILNEKLEAIQNKGKRKKSRNKDEL", "length": 809, "header": "tr|A0A8V0ZPK3-1|A0A8V0ZPK3_CHICK Isoform 1 of Endoplasmic reticulum disulfide reductase DNAJC10 OS=Gallus gallus OX=9031 GN=DNAJC10 PE=1 SV=1 CANONICAL=A0A8V0ZPK3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3/entry#A0A8V0ZHF9-1", "sequence": { "sequence": "MEFLLSKGDYPTSFRRSLLVVLVCVMVLVCTDQDYYSLLGVSKEASSREIRQAFKKLALKLHPDKNQNDPNAHDNFLKINRAYEVLKDEDLRKKYDKYGEKGLEDQQQGGRYESWHYYRYDFGIYDDDPEIITLDRGEFDAAVNSGELWFVNFYSPRCSHCHDLAPTWREFAKEMDGVIRIGAVNCGDNRMLCRIKGINSYPSLYVFKTGMQPVKYYGDRSKESLKNFAMQYVTSTVTELWAGNFVNAIETSFASGLGWLITFCAERGDCLSYQTRLKLAGMLEGLANVGWMDCGTQGELCDNLDISSSTTAYFPPGATINNKEKGGVLFLNSLDAREIYQEVMKHLPDFEIISATSLEDHLAHHRWLLFFQFGENDKSSVQEFKKLKFLLKDEHIQVGKFDCLSSPTICNKLYVYQPCLAVFKGKGIEDYEIHHGKKILYDIVAFAKESVNSHVITLGPQNFPGKEKEPWLVDFFAPWCPPCRALLPELRKASKHLYGQLKFGTLDCTVHEGLCNMHNIRAYPTTVVFNQSDVHEYEGHHSAEQILEFIEDLRNPSVISLTPETFVELVERRKREEIWMVDFYAPWCGPCQALMPEWKKMARMLNGLISVGSVDCQKFYSFCHQENVRGYPEIRLFPQKSSTAHQYYSYNGWHRDSYSLRGWALGYLPRVSIDLTPQSFTEKVLNGKDHWVIDFYAPWCGPCQNFAPEFEILARAVKGKVKAGKVDCQNSRYSKAVNIEDAP", "length": 743, "header": "tr|A0A8V0ZHF9-1|A0A8V0ZPK3_CHICK Computationally mapped isoform of Endoplasmic reticulum disulfide reductase DNAJC10 OS=Gallus gallus OX=9031 GN=DNAJC10 PE=1 SV=1 CANONICAL=A0A8V0ZPK3-1" }, "locus": { "chromosome": "7", "start_pos": 13510937, "end_pos": 13492224, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054256.1", "url": "https://www.ensembl.org/id/ENSGALT00010054256.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032755.1", "url": "https://www.ensembl.org/id/ENSGALP00010032755.1" } ] } }, { "isoform_ac": "A0A8V0ZPK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3/entry#A0A8V0ZPK3-1", "sequence": { "sequence": "MEFLLSKGDYPTSFRRSLLVVLVCVMVLVCTDQDYYSLLGVSKEASSREIRQAFKKLALKLHPDKNQNDPNAHDNFLKINRAYEVLKDEDLRKKYDKYGEKGLEDQQQGGRYESWHYYRYDFGIYDDDPEIITLDRGEFDAAVNSGELWFVNFYSPRCSHCHDLAPTWREFAKEMDGVIRIGAVNCGDNRMLCRIKGINSYPSLYVFKTGMQPVKYYGDRSKESLKNFAMQYVTSTVTELWAGNFVNAIETSFASGLGWLITFCAERGDCLSYQTRLKLAGMLEGLANVGWMDCGTQGELCDNLDISSSTTAYFPPGATINNKEKGGVLFLNSLDAREIYQEVMKHLPDFEIISATSLEDHLAHHRWLLFFQFGENDKSSVQEFKKLKFLLKDEHIQVGKFDCLSSPTICNKLYVYQPCLAVFKGKGIEDYEIHHGKNDFLSTLFFEGKKILYDIVAFAKESVNSHVITLGPQNFPGKEKEPWLVDFFAPWCPPCRALLPELRKASKHLYGQLKFGTLDCTVHEGLCNMHNIRAYPTTVVFNQSDVHEYEGHHSAEQILEFIEDLRNPSVISLTPETFVELVERRKREEIWMVDFYAPWCGPCQALMPEWKKMARMLNGLISVGSVDCQKFYSFCHQENVRGYPEIRLFPQKSSTAHQYYSYNGWHRDSYSLRGWALGYLPRVSIDLTPQSFTEKVLNGKDHWVIDFYAPWCGPCQNFAPEFEILARAVKGKVKAGKVDCQAYGQTCQSADIRAYPTVKFYPYQGTKKSVLGEYIDSRDAKGIADILNEKLEAIQNKGKRKKSRNKDEL", "length": 809, "header": "tr|A0A8V0ZPK3-1|A0A8V0ZPK3_CHICK Isoform 1 of Endoplasmic reticulum disulfide reductase DNAJC10 OS=Gallus gallus OX=9031 GN=DNAJC10 PE=1 SV=1 CANONICAL=A0A8V0ZPK3-1" }, "locus": { "chromosome": "7", "start_pos": 13510937, "end_pos": 13492289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054261.1", "url": "https://www.ensembl.org/id/ENSGALT00010054261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032759.1", "url": "https://www.ensembl.org/id/ENSGALP00010032759.1" } ] } }, { "isoform_ac": "A0A8V0ZQ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3/entry#A0A8V0ZQ14-1", "sequence": { "sequence": "MEFLLSKGDYPTSFRRSLLVVLVCVMVLVCTDQDYYSLLGVSKEASSREIRQAFKKLALKLHPDKNQNDPNAHDNFLKINRAYEVLKDEDLRKKYDKYGEKGLEDQQQGGRYESWHYYRYDFGIYDDDPEIITLDRGEFDAAVNSGELWFVNFYSPRCSHCHDLAPTWREFAKEMDGVIRIGAVNCGDNRMLCRIKGINSYPSLYVFKTGMQPVKYYGDRSKESLKNFAMQYVTSTVTELWADCLSYQTRLKLAGMLEGLANVGWMDCGTQGELCDNLDISSSTTAYFPPGATINNKEKGGVLFLNSLDAREIYQEVMKHLPDFEIISATSLEDHLAHHRWLLFFQFGENDKSSVQEFKKLKFLLKDEHIQVGKFDCLSSPTICNKLYVYQPCLAVFKGKGIEDYEIHHGKKILYDIVAFAKESVNSHVITLGPQNFPGKEKEPWLVDFFAPWCPPCRALLPELRKASKHLYGQLKFGTLDCTVHEGLCNMHNIRAYPTTVVFNQSDVHEYEGHHSAEQILEFIEDLRNPSVISLTPETFVELVERRKREEIWMVDFYAPWCGPCQALMPEWKKMARMLNGLISVGSVDCQKFYSFCHQENVRGYPEIRLFPQKSSTAHQYYSYNGWHRDSYSLRGWALGYLPRVSIDLTPQSFTEKVLNGKDHWVIDFYAPWCGPCQNFAPEFEILARAVKGKVKAGKVDCQAYGQTCQSADIRAYPTVKFYPYQGTKKSVLGEYIDSRDAKGIADILNEKLEAIQNKGKRKKSRNKDEL", "length": 771, "header": "tr|A0A8V0ZQ14-1|A0A8V0ZQ14_CHICK Computationally mapped isoform of Endoplasmic reticulum disulfide reductase DNAJC10 OS=Gallus gallus OX=9031 GN=DNAJC10 PE=1 SV=1 CANONICAL=A0A8V0ZPK3-1" }, "locus": { "chromosome": "7", "start_pos": 13510937, "end_pos": 13492289, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054247.1", "url": "https://www.ensembl.org/id/ENSGALT00010054247.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032748.1", "url": "https://www.ensembl.org/id/ENSGALP00010032748.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" }, { "name": "endoplasmic reticulum chaperone complex", "id": "GO:0034663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034663", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" }, { "name": "ATPase binding", "id": "GO:0051117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051117", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" }, { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" }, { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" }, { "name": "misfolded protein binding", "id": "GO:0051787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor", "id": "GO:0016671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016671", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" }, { "name": "IRE1-mediated unfolded protein response", "id": "GO:0036498", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036498", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "id": "GO:0070059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" }, { "name": "protein folding in endoplasmic reticulum", "id": "GO:0034975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21064", "name": "", "equation": "[protein]-disulfide + 2 glutathione = [protein]-dithiol + glutathione disulfide", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V1A059-1", "A0A8V0ZPK3-1" ], "evidence": [ { "id": "21064", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/21064" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZPK3", "gene_name": "DNAJC10", "activity": [ { "ec_number": "1.8.4.2", "activity": "[protein]-disulfide + 2 glutathione = [protein]-dithiol + glutathione disulfide.", "evidence": [ { "id": "A0A8V0ZPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ] }, { "ec_number": "1.8.4.2", "activity": "", "evidence": [ { "id": "A0A8V0ZPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" } ] } ] }, { "uniprot_ac": "A0A8V1A059", "gene_name": "TXNDC12", "activity": [ { "ec_number": "1.8.4.2", "activity": "[protein]-disulfide + 2 glutathione = [protein]-dithiol + glutathione disulfide.", "evidence": [ { "id": "A0A8V1A059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A059" } ] }, { "ec_number": "1.8.4.2", "activity": "", "evidence": [ { "id": "A0A8V1A059", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A059" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 99, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK3" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin", "eco_id": "ECO_0000259", "start_pos": 120, "end_pos": 234, "start_aa": "Tyr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.8.4.2", "ec_name": "[protein]-disulfide + 2 glutathione = [protein]-dithiol + glutathione disulfide.", "evidence": [ { "id": "1.8.4.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.4.2" }, { "id": "1.8.4.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.8.4.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 542, "end_pos": 544 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPM3-1", "uniprot_ac": "A0A8V0ZPM3", "uniprot_id": "A0A8V0ZPM3_CHICK", "mass": { "chemical_mass": 80479.0, "monoisotopic_mass": 80479.0 }, "refseq": { "ac": "XP_015146387", "name": "nexilin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146387" }, "gene_names": [ { "name": "NEXN", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ] }, { "name": "NEXN", "type": "synonym", "evidence": [ { "id": "XP_015146387", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146387" } ] } ], "protein_names": [ { "name": "Nexilin F-actin binding protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3/entry#names_and_taxonomy" } ] }, { "name": "nexilin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015146387", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146387" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015146387.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146387", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146387" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NEXN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3", "locus": { "chromosome": "8", "start_pos": 18605990, "end_pos": 18630843, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022290", "url": "https://www.ensembl.org/id/ENSGALG00010022290" } ] } } ], "crossref": [ { "id": "A0A8V0ZPM3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "424552", "url": "https://www.ncbi.nlm.nih.gov/gene/424552", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHJ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZHJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPJ4", "url": "https://www.orthodb.org/?gene=A0A8V0ZPJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPL8", "url": "https://www.orthodb.org/?gene=A0A8V0ZPL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPM3", "url": "https://www.orthodb.org/?gene=A0A8V0ZPM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ47", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVA6", "url": "https://www.orthodb.org/?gene=A0A8V0ZVA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21508", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21508", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21508:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21508:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146387", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146387", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNDIAQKTEILLSSSKPVQKSYVPKLHKGDVKDKFEAMQKAREERNQRRSRDEKQRRKEQYVREREWNRRKQEMKELLASDEDDDTKSSKTDKGYVPKLIGTVKGKFAEMEKQRQEEERKRTEEERKRRIEQDMIEKRKIQRELAKKAQEIDDFNNTGTESAAEEGDDSLLVTVVPVKPNKTPGKMKINFDNTGKVRAEQKSRPDEEMKLKYEEQNEFLKENKCLSFLTGENQDSETQSSLSPGKLKVTFEELERQRQENQRRQAEVEAKQRLEEEKRAFEEARQQMINEGGHEESENSGREFRPGKLRLSFEEMERLRREEEKRRAEQDARRRIEEEKRAFAEARKNMVLDDDESPEMFKTFSQESLIPGKLEINFEEMLRQKMEEEKRRTEEERRQKLEMEKQEFQQLRQEMGELEEESETFELSKEYEELIKLKRSGSIQAKNLKSKFEKIGQLSQEEIQKKIEEERAKRRAMDEEIREREAEKFQEDDEVDVRPAKKSEAPFTHKVNMKARFEQMARAREEEEQRRIEEQKLLRMQFEQKEIDAALQKKREEEEDDEGSVINGSTCEDEEDQARSGAPWFKKSLKNTSVVDGEPVRFTVKITGEPKPQVTWWFEGEMLQDSEDYQYIERGETYCLYLPETFPEDEGEYMCKAVNNRGTSASTCILTIETDDY", "length": 676, "header": "tr|A0A8V0ZPM3-1|A0A8V0ZPM3_CHICK Isoform 1 of Nexilin F-actin binding protein OS=Gallus gallus OX=9031 GN=NEXN PE=1 SV=1 CANONICAL=A0A8V0ZPM3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3/entry#A0A8V0ZHJ0-1", "sequence": { "sequence": "MNDIAQKTEMKELLASDEDDDTKSSKTDKGYVPKLIGTVKGKFAEMEKQRQEEERKRTEEERKRRIEQDMIEKRKIQRELAKKAQEEGDDSLLVTVVPVKPNKTPGKMKINFDNTGKVRAEQKSRPDEEMKLKYEEQNEFLKENKCLSFLTGENQDSETQSSLSPGKLKVTFEELERQRQENQRRQAEVEAKQRLEEEKRAFEEARQQMINEGGHEESENSGREFRPGKLRLSFEEMERLRREEEKRRAEQDARRRIEEEKRAFAEARKNMVLDDDESPEMFKTFSQESLIPGKLEINFEEMLRQKMEEEKRRTEEERRQKLEMEKQEFQQLRQEMGELEEESETFELSKEYEELIKLKRSGSIQAKNLKSKFEKIGQLSQEEIQKKIEEERAKRRAMDEEIREREAEKFQEDDEVDVRPAKKSEAPFTHKVNMKARFEQMARAREEEEQRRIEEQKLLRMQFEQKEIDAALQKKREEEEDDEGSVINGSTCEDEEDQARSGAPWFKKSLKNTSVVDGEPVRFTVKITGEPKPQVTWWFEGEMLQDSEDYQYIERGETYCLYLPETFPEDEGEYMCKAVNNRGTSASTCILTIESKS", "length": 597, "header": "tr|A0A8V0ZHJ0-1|A0A8V0ZPM3_CHICK Computationally mapped isoform of Nexilin F-actin binding protein OS=Gallus gallus OX=9031 GN=NEXN PE=1 SV=1 CANONICAL=A0A8V0ZPM3-1" }, "locus": { "chromosome": "8", "start_pos": 18622505, "end_pos": 18606575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054289.1", "url": "https://www.ensembl.org/id/ENSGALT00010054289.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032785.1", "url": "https://www.ensembl.org/id/ENSGALP00010032785.1" } ] } }, { "isoform_ac": "A0A8V0ZPJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3/entry#A0A8V0ZPJ4-1", "sequence": { "sequence": "MQKAREERNQRRSRDEKQRRKEQYVREREWNRRKQEMKELLASDEDDDTKSSKTDKGYVPKLIGTVKGKFAEMEKQRQEEERKRTEEERKRRIEQDMIEKRKIQRELAKKAQEEGDDSLLVTVVPVKPNKTPGKMKINFDNTGKVRAEQKSRPDEEMKLKYEEQNEFLKENKCLSFLTGENQDSETQSSLSPGKLKVTFEELERQRQENQRRQAEVEAKQRLEEEKRAFEEARQQMINEGGHEESENSGREFRPGKLRLSFEEMERLRREEEKRRAEQDARRRIEEEKRAFAEARKNMQVLDDDESPEMFKTFSQESLIPGKLEINFEEMLRQKMEEEKRRTEEERRQKLEMEKQEFQQLRQEMGELEEESETFELSKEYEELIKLKRSGSIQAKNLKSKFEKIGQLSQEEIQKKIEEERAKRRAMDEEIREREAEKFQEDDEVDVRPAKKSEAPFTHKVNMKARFEQMARAREEEEQRRIEEQKLLRMQFEQKEIDAALQKKREEEEDDEGSVINGSTCEDEEDQARSGAPWFKKSLKNTSVVDGEPVRFTVKITGEPKPQVTWWFEGEMLQDSEDYQYIERGETYCLYLPETFPEDEGEYMCKAVNNRGTSASTCILTIETDDY", "length": 626, "header": "tr|A0A8V0ZPJ4-1|A0A8V0ZPJ4_CHICK Computationally mapped isoform of Nexilin F-actin binding protein OS=Gallus gallus OX=9031 GN=NEXN PE=1 SV=1 CANONICAL=A0A8V0ZPM3-1" }, "locus": { "chromosome": "8", "start_pos": 18621301, "end_pos": 18606466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054241.1", "url": "https://www.ensembl.org/id/ENSGALT00010054241.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032749.1", "url": "https://www.ensembl.org/id/ENSGALP00010032749.1" } ] } }, { "isoform_ac": "A0A8V0ZPL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3/entry#A0A8V0ZPL8-1", "sequence": { "sequence": "MNDIAQKTEILLSSSKPVQKSYVPKLHKGDVKDKFEAMQKAREERNQRRSRDEKQRRKEQYVREREWNRRKQEMKELLASDEDDDTKSSKTDKGYVPKLIGTVKGKFAEMEKQRQEEERKRTEEERKRRIEQDMIEKRKIQRELAKKAQEIDDFNNTGTESAAEEGDDSLLVTVVPVKPNKTPGKMKINFDNTGKVRAEQKSRPDEEMKLKYEEQNEFLKENKCLSFLTGENQDSETQSSLSPGKLKVTFEELERQRQENQRRQAEVEAKQRLEEEKRAFEEARQQMINEGGHEESENSGREFRPGKLRLSFEEMERLRREEEKRRAEQDARRRIEEEKRAFAEARKNMVLDDDESPEMFKTFSQESLIPGKLEINFEEMLRQKMEEEKRRTEEERRQKLEMEKQEFQQLRQEMGELEEESETFELSKEYEELIKLKRSGSIQAKNLKSKFEKIGQLSQEEIQKKIEEERAKRRAMDEEIREREAEKFQEDDEVDVRPAKKSEAPFTHKVNMKARFEQMARAREEEEQRRIEEQKLLRMQFEQKEIDAALQKKREEEEDDEGSVINGSTCEDEEDQARSGAPWFKKSLKNTSVVDGEPVRFTVKITGEPKPQVTWWFEGEMLQDSEDYQYIERGETYCLYLPETFPEDEGEYMCKAVNNRGTSASTCILTIESKS", "length": 675, "header": "tr|A0A8V0ZPL8-1|A0A8V0ZPL8_CHICK Computationally mapped isoform of Nexilin F-actin binding protein OS=Gallus gallus OX=9031 GN=NEXN PE=1 SV=1 CANONICAL=A0A8V0ZPM3-1" }, "locus": { "chromosome": "8", "start_pos": 18622505, "end_pos": 18606575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054277.1", "url": "https://www.ensembl.org/id/ENSGALT00010054277.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032774.1", "url": "https://www.ensembl.org/id/ENSGALP00010032774.1" } ] } }, { "isoform_ac": "A0A8V0ZPM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3/entry#A0A8V0ZPM3-1", "sequence": { "sequence": "MNDIAQKTEILLSSSKPVQKSYVPKLHKGDVKDKFEAMQKAREERNQRRSRDEKQRRKEQYVREREWNRRKQEMKELLASDEDDDTKSSKTDKGYVPKLIGTVKGKFAEMEKQRQEEERKRTEEERKRRIEQDMIEKRKIQRELAKKAQEIDDFNNTGTESAAEEGDDSLLVTVVPVKPNKTPGKMKINFDNTGKVRAEQKSRPDEEMKLKYEEQNEFLKENKCLSFLTGENQDSETQSSLSPGKLKVTFEELERQRQENQRRQAEVEAKQRLEEEKRAFEEARQQMINEGGHEESENSGREFRPGKLRLSFEEMERLRREEEKRRAEQDARRRIEEEKRAFAEARKNMVLDDDESPEMFKTFSQESLIPGKLEINFEEMLRQKMEEEKRRTEEERRQKLEMEKQEFQQLRQEMGELEEESETFELSKEYEELIKLKRSGSIQAKNLKSKFEKIGQLSQEEIQKKIEEERAKRRAMDEEIREREAEKFQEDDEVDVRPAKKSEAPFTHKVNMKARFEQMARAREEEEQRRIEEQKLLRMQFEQKEIDAALQKKREEEEDDEGSVINGSTCEDEEDQARSGAPWFKKSLKNTSVVDGEPVRFTVKITGEPKPQVTWWFEGEMLQDSEDYQYIERGETYCLYLPETFPEDEGEYMCKAVNNRGTSASTCILTIETDDY", "length": 676, "header": "tr|A0A8V0ZPM3-1|A0A8V0ZPM3_CHICK Isoform 1 of Nexilin F-actin binding protein OS=Gallus gallus OX=9031 GN=NEXN PE=1 SV=1 CANONICAL=A0A8V0ZPM3-1" }, "locus": { "chromosome": "8", "start_pos": 18622505, "end_pos": 18606466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054282.1", "url": "https://www.ensembl.org/id/ENSGALT00010054282.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032779.1", "url": "https://www.ensembl.org/id/ENSGALP00010032779.1" } ] } }, { "isoform_ac": "A0A8V0ZQ47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3/entry#A0A8V0ZQ47-1", "sequence": { "sequence": "MNDIAQKTEILLSSSKPVQKSYVPKLHKGDVKDKFEAMQKAREERNQRRSRDEKQRRKEQYVREREWNRRKQEMKELLASDEDDDTKSSKTDKGYVPKLIGTVKGKFAEMEKQRQEEERKRTEEERKRRIEQDMIEKRKIQRELAKKAQEEGDDSLLVTVVPVKPNKTPGKMKINFDNTGKVRAEQKSRPDEEMKLKYEEQNEFLKENKCLSFLTGENQDSETQSSLSPGKLKVTFEELERQRQENQRRQAEVEAKQRLEEEKRAFEEARQQMINEGGHEESENSGREFRPGKLRLSFEEMERLRREEEKRRAEQDARRRIEEEKRAFAEARKNMVLDDDESPEMFKTFSQESLIPGKLEINFEEMLRQKMEEEKRRTEEERRQKLEMEKQEFQQLRQEMGELEEESETFELSKEYEELIKLKRSGSIQAKNLKSKFEKIGQLSQEEIQKKIEEERAKRRAMDEEIREREAEKFQEDDEVDVRPAKKSEAPFTHKVNMKARFEQMARAREEEEQRRIEEQKLLRMQFEQKEIDAALQKKREEEEDDEGSVINGSTCEDEEDQARSGAPWFKKSLKNTSVVDGEPVRFTVKITGEPKPQVTWWFEGEMLQDSEDYQYIERGETYCLYLPETFPEDEGEYMCKAVNNRGTSASTCILTIETDDY", "length": 662, "header": "tr|A0A8V0ZQ47-1|A0A8V0ZQ47_CHICK Computationally mapped isoform of Nexilin F-actin binding protein OS=Gallus gallus OX=9031 GN=NEXN PE=1 SV=1 CANONICAL=A0A8V0ZPM3-1" }, "locus": { "chromosome": "8", "start_pos": 18622505, "end_pos": 18606466, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054293.1", "url": "https://www.ensembl.org/id/ENSGALT00010054293.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032788.1", "url": "https://www.ensembl.org/id/ENSGALP00010032788.1" } ] } }, { "isoform_ac": "A0A8V0ZVA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3/entry#A0A8V0ZVA6-1", "sequence": { "sequence": "MNDIAQKTEMKELLASDEDDDTKSSKTDKGYVPKLIGTVKGKFAEMEKQRQEEERKRTEEERKRRIEQDMIEKRKIQRELAKKAQEVWWSDQNKIDDFNNTGTESAAEEGDDSLLVTVVPVKPNKTPGKMKINFDNTGKVRAEQKSRPDEEMKLKYEEQNEFLKENKCLSFLTGENQDSETQSSLSPGKLKVTFEELERQRQENQRRQAEVEAKQRLEEEKRAFEEARQQMINEGGHEESENSGREFRPGKLRLSFEEMERLRREEEKRRAEQDARRRIEEEKRAFAEARKNMVLDDDESPEMFKTFSQESLIPGKLEINFEEMLRQKMEEEKRRTEEERRQKLEMEKQEFQQLRQEMGELEEESETFELSKEYEELIKLKRSGSIQAKNLKSKFEKIGQLSQEEIQKKIEEERAKRRAMDEEIREREAEKFQEDDEVDVRPAKKSEAPFTHKVNMKARFEQMARAREEEEQRRIEEQKLLRMQFEQKEIDAALQKKREEEEDDEGSVINGSTCEDEEDQARSGAPWFKKSLKNTSVVDGEPVRFTVKITGEPKPQVTWWFEGEMLQDSEDYQYIERGETYCLYLPETFPEDEGEYMCKAVNNRGTSASTCILTIESKS", "length": 619, "header": "tr|A0A8V0ZVA6-1|A0A8V0ZPM3_CHICK Computationally mapped isoform of Nexilin F-actin binding protein OS=Gallus gallus OX=9031 GN=NEXN PE=1 SV=1 CANONICAL=A0A8V0ZPM3-1" }, "locus": { "chromosome": "8", "start_pos": 18622505, "end_pos": 18606575, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054290.1", "url": "https://www.ensembl.org/id/ENSGALT00010054290.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032786.1", "url": "https://www.ensembl.org/id/ENSGALP00010032786.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" }, { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" }, { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" }, { "name": "regulation of cytoskeleton organization", "id": "GO:0051493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051493", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" }, { "name": "dendrite self-avoidance", "id": "GO:0070593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPM3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPM3" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 582, "end_pos": 670, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 180, "end_pos": 182 }, { "start_pos": 566, "end_pos": 568 }, { "start_pos": 590, "end_pos": 592 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNL1-1", "uniprot_ac": "A0A8V0ZNL1", "uniprot_id": "A0A8V0ZNL1_CHICK", "mass": { "chemical_mass": 46589.0, "monoisotopic_mass": 46589.0 }, "refseq": {}, "gene_names": [ { "name": "SH2D5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL1" } ] } ], "protein_names": [ { "name": "SH2 domain containing 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SH2D5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL1", "locus": { "chromosome": "21", "start_pos": 6739676, "end_pos": 6733777, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021109", "url": "https://www.ensembl.org/id/ENSGALG00010021109" } ] } } ], "crossref": [ { "id": "A0A8V0ZNL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00173", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00173", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769539", "url": "https://www.ncbi.nlm.nih.gov/gene/769539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769539", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769539", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDCGPEG", "url": "https://omabrowser.org/oma/group/QDCGPEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHM0", "url": "https://www.orthodb.org/?gene=A0A8V0ZHM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNL1", "url": "https://www.orthodb.org/?gene=A0A8V0ZNL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15832:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15832:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKKMTANGRGPDPAPPPPRARGIAKSAEYVGSFMVEELELQQHVGQLEEQLRALKDCPRRRSVVLRFSLQGLKVYGDDGETLLMAHALRRILYSTCLHAERQFAFVARNPHSPPSTLFCHLFVSPVGEVHVLHLLLCRSFQLCYLQAHPELQAAEPDPPVLLRETLNPEEVSRNVNALLSLRRLPALGPLGAGHVFAQHLLQERRVEAEGRAVGWRPGNPYCSPVLVRKKAIRSKVLRSGAYRDCGAESQLQQREGGIGFGALKEDPGGQERDLGPDTHPPPSAPSGWESRGMRGLVLLPDTEAALAESVWAFAGIARASGIALLRGDVPGAFLLRPEPGATPRWCLWVHTPCGVVPYCVLRTQQGRFCVEHSHAEFRSMPALLAHYSAVPGGCFCRLSVGRCNPGYEQRDEDGPALVQHERG", "length": 424, "header": "tr|A0A8V0ZNL1-1|A0A8V0ZNL1_CHICK Isoform 1 of SH2 domain containing 5 OS=Gallus gallus OX=9031 GN=SH2D5 PE=4 SV=1 CANONICAL=A0A8V0ZNL1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL1/entry#A0A8V0ZHM0-1", "sequence": { "sequence": "MKKKMTANGRGPDPAPPPPRARGIAKSAEYVGSFMVEELELQQHVGQLEEQLRALKDCPRRRSVVLRFSLQGLKVYGDDGETLLMAHALRRILYSTCLHAERQFAFVARNPHSPPSTLFCHLFVSPVGEVHVLHLLLCRSFQLCYLQAHPELQAAEPDPPVLLRETLNPEEVSRNVNALLSLRRLPALGPLGAGHVFAQHLLQERRVEAEGRAVGWRPGNPYCSPVLVRKKAIRSKVLRSGAYRDCGAESQLQQREGAPSGWESRGMRGLVLLPDTEAALAESVWAFAGIARASGIALLRGDVPGAFLLRPEPGATPRWCLWVHTPCGVVPYCVLRTQQGRFCVEHSHAEFRSMPALLAHYSAVPGGCFCRLSVGRCNPGYEQRDEDGPALVQHERG", "length": 397, "header": "tr|A0A8V0ZHM0-1|A0A8V0ZNL1_CHICK Computationally mapped isoform of SH2 domain containing 5 OS=Gallus gallus OX=9031 GN=SH2D5 PE=4 SV=1 CANONICAL=A0A8V0ZNL1-1" }, "locus": { "chromosome": "21", "start_pos": 6739612, "end_pos": 6734952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051102.1", "url": "https://www.ensembl.org/id/ENSGALT00010051102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030293.1", "url": "https://www.ensembl.org/id/ENSGALP00010030293.1" } ] } }, { "isoform_ac": "A0A8V0ZNL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL1/entry#A0A8V0ZNL1-1", "sequence": { "sequence": "MKKKMTANGRGPDPAPPPPRARGIAKSAEYVGSFMVEELELQQHVGQLEEQLRALKDCPRRRSVVLRFSLQGLKVYGDDGETLLMAHALRRILYSTCLHAERQFAFVARNPHSPPSTLFCHLFVSPVGEVHVLHLLLCRSFQLCYLQAHPELQAAEPDPPVLLRETLNPEEVSRNVNALLSLRRLPALGPLGAGHVFAQHLLQERRVEAEGRAVGWRPGNPYCSPVLVRKKAIRSKVLRSGAYRDCGAESQLQQREGGIGFGALKEDPGGQERDLGPDTHPPPSAPSGWESRGMRGLVLLPDTEAALAESVWAFAGIARASGIALLRGDVPGAFLLRPEPGATPRWCLWVHTPCGVVPYCVLRTQQGRFCVEHSHAEFRSMPALLAHYSAVPGGCFCRLSVGRCNPGYEQRDEDGPALVQHERG", "length": 424, "header": "tr|A0A8V0ZNL1-1|A0A8V0ZNL1_CHICK Isoform 1 of SH2 domain containing 5 OS=Gallus gallus OX=9031 GN=SH2D5 PE=4 SV=1 CANONICAL=A0A8V0ZNL1-1" }, "locus": { "chromosome": "21", "start_pos": 6739612, "end_pos": 6734952, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051100.1", "url": "https://www.ensembl.org/id/ENSGALT00010051100.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030291.1", "url": "https://www.ensembl.org/id/ENSGALP00010030291.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769539", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769539", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MJ64-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "Sh2d5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRAGAGARRASDCGPAPYRPRCIAKFAQYVGSFPVDDLDTQESVCLVQQHLWALQDCSRRRAVILKFSLQGLKIYSGEGEVLLMAHALKRILYATWNPAACQFAFVARNPRSPASKLFCHLFVGSQPGEINILYLLLCRSFQLAYLLQHPEERAQPEPSLVPGGDMSLKPLCSPGVAPALVREPFSRDQLSQNVHALVSFRRLPAEGLLGSNGKELPEPEGRGGTRHIRLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRGPGSPSCLVENEGSLTENIWAFAGLSRSCALALLRRDVHGAFLLWPEPGTSGQWSLSVRTQCGVVSHQVFRNHLGRYCLEHLPAEFPSLEALVESHAGMERSLFCPLSMGRLNPTYEEQDSGPEGRFPRTLRPLSHAKSEAELQGLG", "length": 429 }, "evidence": [ { "id": "A0A8V0ZNL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNL1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3L7I8M5-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "Sh2d5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQRAGAGARRASDCGPAPYRPRCIAKFAQYVGSFPVEDLDTQEGVYLVQQQLWALQDCSRRRAVILKFSLQGLKVYSGEGEVLLMAHALKRILYATWCPAACQFAFVARNPRSPASKLYCHLFVGSQPGEVHILYLLLCRSFQLAYLLQHPEERAQPEPCLGPMGDMSPKPLCSPGTPPVLVREPFSRDQLSQNVHALVSFRRVPAEGLLGGSGKELPEPEGRGGPRHTRLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRSPGGPSCLVENEGSLTENIWAFAGLSKPCALALLRRDVHGAFLLWPEPGTSDQWSLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVESHAGMERSLFCPLSMGRLNPTYEEQDCGPEGRLPRTLRPLSHAKSEAELQGLG", "length": 429 }, "evidence": [ { "id": "A0A8V0ZNL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNL1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "E1BA40-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "SH2D5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQKAGAGGRRASDCGPAPQRPRCITKFAQYVGSFPVDDLDPQESVWLVQQQLWALKDCPRRRAVILKFSLQGLKIYSGEGEVLLMAHALRRILYATWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQLAYLLQHPEERARPEPCPEPVGDAPLKPVPGPGGPPGLVREPFGRDQLSQNVNALVSFRRLPAEGSGGSGKELLESASRGGTRHLRLGNPYCSPTLVRKKAIRSKVLRSGAYRACTYETQLQLSAREALPAAWEAWPRGPGGPSCLVESEGSLTENIWAFAGISRTSALALLRRDVLGAFLLWPEPGANGQWCLSVRTQCGVVPHQVFRNHVGRYCVEHLPAEFPSLEALVEHHAGTERSLFCSLDMGRLNPGYEEQDCGPSGQPPRTLRPLGHAKSEAELQGLG", "length": 428 }, "evidence": [ { "id": "A0A8V0ZNL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNL1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1Q5B0-1", "protein_name": "SH2 domain-containing protein 5 isoform 1", "gene_name": "sh2d5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFKRQTPQPGSVWNMGETAGREHGTVTRSAEYIGSFPVDDSCLDDQIQQLHTQLKSLKNCKSKRTVSLRFSVKGVKVYDEDETTLLMAHAMCRVSLSTARPSDAQFAFASHNPGNSDAQLYCHLFRARHARAAQFLNLLLCRCFQLYFLEKHPEEAQEECSGKKPSRAPSLLNQGFPLSVSALVSFRRAPTQGLLPGAKLFSQQSTEQVSSPEEGPTSSPTIVRKMAIRTKELRSGAYRSFTFTPLKQRHLQDKLSAPQEKEQATAKACMSRAPSLAETEEALAQAVWCWAGVSSDCSSSLLADDVLGAFLLCPHPKKPNRGSLIVRFSSGLVTYAIKNSKGKFRLEKCHTDFESLAALMEHYTEFGDELECSLSCARVNHCYDWEEMVNKGSRLLQDNKKGTFKCRSWV", "length": 410 }, "evidence": [ { "id": "A0A8V0ZNL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNL1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SU08-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "SH2D5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQKAGAGGRRASDCGPAPHRPRCITKFAQYVGSFPVDDLDTQERVWLVQQQLWALKDCPRRRAVILKFSLQGLKIYSGEGEVLLMAHALRRILYTTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQLAYLLQHPEERAQPEPCLGPAGDVALKPLSCPGGPSGLVREPFGRDQLSQNVNALVSFRRLPAEGPGGSGKELPESESRGGARHTRLGNPYCSPTLVRKKAIRSKVIRSGAYRACTYETQLQLSAREAFPALWEAWPRGPGSPSCLVESEGSLTENIWAFAGISRPSALALLRRDVLGAFLLWPEPGANGQWCLSVRTQCGVVPHQVFRNHLGRYCVEHLPAEFPSLEALVEHHAGTERSLFCSLDMGRLNPN", "length": 396 }, "evidence": [ { "id": "A0A8V0ZNL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNL1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6ZV89-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "SH2D5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQKAGAGGRRASDCGLAPHRPRCITKFAQYVGSFPVDDLDTQESVWLVQQQLWALKDCPRRRAVILKFSLQGLKIYSGEGEVLLMAHALRRILYSTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQLAYLLQHPEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAEGLVGSGKELPESEGRARHARLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRGPGGHSCLVESEGSLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPLDMGRLNPTYEEQDCGPPGRPPRTLRPLSHAKSEAELQGLG", "length": 423 }, "evidence": [ { "id": "A0A8V0ZNL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNL1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8JZW5-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "Sh2d5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRAGAGARRASDCGPAPYRPRCIAKLAQYVGSFPVDDLDTQESVGLVQQQLWALQDCSRRRAVILKFSLQGLKIYSGEGEVLLMAHALKRILYATWYPAACQFAFIARNPRSPSSKLFCHLFVGSQPGEVHILYLLLCRSFQLAYLLQHPEERAQSEPCLAPVGDLSLKPLCSPGVPPALVREPFSRDQLSQNVHALVSFRRLPAEGLLGSNGKELPESEGRGGTRHIRLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRGPGGPSCLVENEGSLTENIWAFAGLSRSCALSLLRRDVHGAFLLWPEPGTSDQWSLSVRTQCGVVPHQVFRNHLGRFCLEHLPAEFPSLEALVESHAGVERSLFCPLSMGRLNPTYEEQDCGTEGRFPRTLRPLSHAKSEAELQGLG", "length": 429 }, "evidence": [ { "id": "A0A8V0ZNL1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNL1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL1" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 123, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZNL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNL1" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 312, "end_pos": 403, "start_aa": "Trp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQ42-1", "uniprot_ac": "A0A8V0ZQ42", "uniprot_id": "A0A8V0ZQ42_CHICK", "mass": { "chemical_mass": 115042.0, "monoisotopic_mass": 115042.0 }, "refseq": {}, "gene_names": [ { "name": "ARHGAP39L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 39", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGAP39L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZQ42", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQ42", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04389", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04389", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHS4", "url": "https://www.orthodb.org/?gene=A0A8V0ZHS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ42", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45876", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45876", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45876:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45876:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00784", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00784", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZHS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHNKSSTSSDWVEIIEPRSQERMYVNLTTGECGWEPPPNLKVRQSDQKQWWELFDHNNNRFYYYNAITQQTVWHRPQGCDIVPLAQLQAMKHSSQPDCRGRQHRGSSGSEGRSTPIPTALLQEMERGKGDCATDRRPDTGRETPTHWQPLPGTKAAMLVKVNSLKQVPGSSNSSLHLQSAPETNSQKPLSKAAIYAQPQSVSQSPGATKQIPAGEGKQSMQIKKTENGGFCLVLMNGPASQTPPRSRTGTPQPASPKYASPAPIYDEPSLESPIYDEPPVDMDTESVGVSGMSPPRSPSNSLKKQLQPTKLLQHPSVQQQQAAKKHARNPSSTEYSPAGREYIKHMVNVDQSSKPSHSAAATADASTKLPGQLASKDSFKQSWRILEANVLKSIEAHHSRQNSLQTQEYPTAISHQDSGYSTGPSPSLRKRKGRRQGAGQGRPGSVGSSSELTALNDKLIAEMRAVVGRSAACRGSKASLDAQSLEGGIPAEGGKVRFQSDHLKKCVGRSSRDDVSASNRSLYRQGLESRGSFPSDMAAPQDTVRQKRTFEKVDSLEKNVTGRASLASSGATRHSSQPGAVELDPKQESSGQPSGCMGYHFSYNTLRKPISQSSMADWASKNLNMHTQGIFRRRISISNMLSWNGGSIKKPMLITSNRTIKKEACEMFKLVQSYMGDRQTRMDRNHVALVTVTKCWSMQGLRDELYIQLIRQTTDNTCYRSLAWGWELMAISLAFFSPSPKFQSYLEGYIYRHLDCDENIAQRIKELVDLKNKKNSKSRKKRKQNTEEEGLPISMYAKYCYRKLQKVAVTGGKKGLRKPTVEEITHARNAIVTPSLFGSSLEEIMLRQQDMYPGHRLPWVQTQLSQQVLALGGEQTEGIFRIPGDIDEVNALKLQVDQWRIPSGLSDPNIPASLLKLWYRELEEPVIPQEFYKECISNYENPDAAVAVVQLLPELNKLVLCYLIHFLQIFAQPSNVGRTKMDVNNLAMVMAPNCLRCQSDDPRIIFENTRKEMSFLRMLIVHLDTSFIKGLV", "length": 1032, "header": "tr|A0A8V0ZQ42-1|A0A8V0ZQ42_CHICK Isoform 1 of Rho GTPase-activating protein 39 OS=Gallus gallus OX=9031 GN=ARHGAP39L PE=4 SV=1 CANONICAL=A0A8V0ZQ42-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42/entry#A0A8V0ZHS4-1", "sequence": { "sequence": "MAESSDWVEIIEPRSQERMYVNLTTGECGWEPPPNLKVRQSDQKQWWELFDHNNNRFYYYNAITQQTVWHRPQGCDIVPLAQLQAMKHSSQPDCRGRQHRGSSGSEGRSTPIPTALLQEMERGKGDCATDRRPDTGRETPTHWQPLPGTKAAMLVKVNSLKQVPGSSNSSLHLQSAPETNSQKPLSKAAIYAQPQSVSQSPGATKQIPAGEGKQSMQIKKTENGGFCLVLMNGPASQTPPRSRTGTPQPASPKYASPAPIYDEPSLESPIYDEPPVDMDTESVGVSGMSPPRSPSNSLKKQLQPTKLLQHPSVQQQQAAKKHARNPSSTEYSPAGREYIKHMVNVDQSSKPSHSAAATADASTKLPGQLASKDSFKQSWRILEANVLKSIEAHHSRQNSLQTQEYPTAISHQDSGYSTGPSPSLRKRKGRRQGAGQGRPGSVGSSSELTALNDKLIAEMRAVVGRSAACRGSKASLDAQSLEGGIPAEGGKVRFQSDHLKKCVGRSSRDDVSASNRSLYRQGLESRGSFPSDMAAPQDTVRQKRTFEKVDSLEKNVTGRASLASSGATRHSSQVPPHPPHPGAVELDPKQESSGQPSGCMGYHFSYNTLRKPISQSSMADWASKNLNMHTQGIFRRRISISNMLSWNGGSIKKPMLITSNRTIKKEACEMFKLVQSYMGDRQTRMDRNHVALVTVTKCWSMQGLRDELYIQLIRQTTDNTCYRSLAWGWELMAISLAFFSPSPKFQSYLEGYIYRHLDCDENIAQRIKELVDLKNKKNSKSRKKRKQNTEEEGLPISMYAKYCYRKLQKVAVTGGKKGLRKPTVEEITHARNAIVTPSLFGSSLEEIMLRQQDMYPGHRLPWVQTQLSQQVLALGGEQTEGIFRIPGDIDEVNALKLQVDQWRIPSGLSDPNIPASLLKLWYRELEEPVIPQEFYKECISNYENPDAAVAVVQLLPELNKLVLCYLIHFLQIFAQPSNVGRTKMDVNNLAMVMAPNCLRCQSDDPRIIFENTRKEMSFLRMLIVHLDTSFIKGLV", 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"length": 1032, "header": "tr|A0A8V0ZQ42-1|A0A8V0ZQ42_CHICK Isoform 1 of Rho GTPase-activating protein 39 OS=Gallus gallus OX=9031 GN=ARHGAP39L PE=4 SV=1 CANONICAL=A0A8V0ZQ42-1" }, "locus": { "chromosome": "20", "start_pos": 1323552, "end_pos": 1288849, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051735.1", "url": "https://www.ensembl.org/id/ENSGALT00010051735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030858.1", "url": "https://www.ensembl.org/id/ENSGALP00010030858.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42" }, { "id": "PS51016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MyTH4", "eco_id": "ECO_0000259", "start_pos": 643, "end_pos": 792, "start_aa": "Trp", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 839, "end_pos": 1027, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ42" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 39, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 519, "end_pos": 521 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 657, "end_pos": 659 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"protein_names": [ { "name": "Switch-associated protein 70", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. 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gallus [9031]" } ], "gene": [ { "name": "SWAP70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0", "locus": { "chromosome": "5", "start_pos": 8948081, "end_pos": 8982058, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021127", "url": "https://www.ensembl.org/id/ENSGALG00010021127" } ] } } ], "crossref": [ { "id": "A0A8V0ZNS0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNS0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000005750", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005750", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423044", "url": "https://www.ncbi.nlm.nih.gov/gene/423044", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423044", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423044", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VEFYKMC", "url": "https://omabrowser.org/oma/group/VEFYKMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHS6", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N8E4", "url": "https://www.uniprot.org/uniprotkb/F1N8E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N8E4-1", "url": "https://www.uniprot.org/uniprotkb/F1N8E4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLWCLFLHASPGFQMRKSMHIKGSFYSNGSVCNHHCNCVKQSNPCGRFLLVKCWCFPFLEKNLRGRTDTDMKVLSHNLCTVLNVPHDPVALEEHFRDDDEGPVSNQGYMPYLNKFILEKVQGNFDKVEFNRMCWTLCAKKNLSKSPLLISDEDAFKVWVIFNFLSEDKYPLIIVPEEIEYLLKKLTEAMGAGWQQEQFDLYKIALNTSREGLSAWELIDLIGSGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMLKKGHKRKNWTERWFVLKPNIISYYVSEDLKDKKGDIILDGNCCVEPLPDKDGKKCLFLIKCLDKSFEISASDKKKKQEWIQAIQTTVSLLRAGSPPPHKEARQKRKELRQKLLAEQEELERQMKELQTANENKQKELETVRKQLEAAAARAAEEEKKRLQTQVELQDRFSLELEREKMVRQKMEEQVAQKSSELEQYLQRVRELEEMYKQLQEALEVEKQARQDEETVRKLQARLLEEESAKRAELEKWHLQQQQTIQMTEAEKQELENQRMIKEQALQVAMQQLEQLELERKEALEQYEEVKKKLETAANNTRSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEQRQKSWKGKKASSE", "length": 626, "header": "tr|A0A8V0ZNS0-1|A0A8V0ZNS0_CHICK Isoform 1 of Switch-associated protein 70 OS=Gallus gallus OX=9031 GN=SWAP70 PE=4 SV=1 CANONICAL=A0A8V0ZNS0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0/entry#A0A8V0ZHS6-1", "sequence": { "sequence": "MRCQQVLSHNLCTVLNVPHDPVALEEHFRDDDEGPVSNQGYMPYLNKFILEKVQGNFDKVEFNRMCWTLCAKKNLSKSPLLISDEDAFKVWVIFNFLSEDKYPLIIVPEEIEYLLKKLTEAMGAGWQQEQFDLYKIALNTSREGLSAWELIDLIGSGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMLKKGHKRKNWTERWFVLKPNIISYYVSEDLKDKKGDIILDGNCCVEPLPDKDGKKCLFLIKCLDKSFEISASDKKKKQEWIQAIQTTVSLLRAGSPPPHKEARQKRKELRQKLLAEQEELERQMKELQTANENKQKELETVRKQLEAAAARAAEEEKKRLQTQVELQDRFSLELEREKMVRQKMEEQVAQKSSELEQYLQRVRELEEMYKQLQEALEVEKQARQDEETVRKLQARLLEEESAKRAELEKWHLQQQQTIQMTEAEKQELENQRMIKEQALQVAMQQLEQLELERKEALEQYEEVKKKLETAANNTRSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEQRQKSWKGKKASSE", "length": 558, "header": "tr|A0A8V0ZHS6-1|A0A8V0ZNS0_CHICK Computationally mapped isoform of Switch-associated protein 70 OS=Gallus gallus OX=9031 GN=SWAP70 PE=4 SV=1 CANONICAL=A0A8V0ZNS0-1" }, "locus": { "chromosome": "5", "start_pos": 8981037, "end_pos": 8950016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051164.1", "url": "https://www.ensembl.org/id/ENSGALT00010051164.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030355.1", "url": "https://www.ensembl.org/id/ENSGALP00010030355.1" } ] } }, { "isoform_ac": "A0A8V0ZNS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0/entry#A0A8V0ZNS0-1", "sequence": { "sequence": "MLLWCLFLHASPGFQMRKSMHIKGSFYSNGSVCNHHCNCVKQSNPCGRFLLVKCWCFPFLEKNLRGRTDTDMKVLSHNLCTVLNVPHDPVALEEHFRDDDEGPVSNQGYMPYLNKFILEKVQGNFDKVEFNRMCWTLCAKKNLSKSPLLISDEDAFKVWVIFNFLSEDKYPLIIVPEEIEYLLKKLTEAMGAGWQQEQFDLYKIALNTSREGLSAWELIDLIGSGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMLKKGHKRKNWTERWFVLKPNIISYYVSEDLKDKKGDIILDGNCCVEPLPDKDGKKCLFLIKCLDKSFEISASDKKKKQEWIQAIQTTVSLLRAGSPPPHKEARQKRKELRQKLLAEQEELERQMKELQTANENKQKELETVRKQLEAAAARAAEEEKKRLQTQVELQDRFSLELEREKMVRQKMEEQVAQKSSELEQYLQRVRELEEMYKQLQEALEVEKQARQDEETVRKLQARLLEEESAKRAELEKWHLQQQQTIQMTEAEKQELENQRMIKEQALQVAMQQLEQLELERKEALEQYEEVKKKLETAANNTRSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEQRQKSWKGKKASSE", "length": 626, "header": "tr|A0A8V0ZNS0-1|A0A8V0ZNS0_CHICK Isoform 1 of Switch-associated protein 70 OS=Gallus gallus OX=9031 GN=SWAP70 PE=4 SV=1 CANONICAL=A0A8V0ZNS0-1" }, "locus": { "chromosome": "5", "start_pos": 8976185, "end_pos": 8950016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051161.1", "url": "https://www.ensembl.org/id/ENSGALT00010051161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030352.1", "url": "https://www.ensembl.org/id/ENSGALP00010030352.1" } ] } }, { "isoform_ac": "F1N8E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0/entry#F1N8E4-1", "sequence": { "sequence": "MVGLKEELLKAIWHAFTALDLDRSGKVSKSQLKVLSHNLCTVLNVPHDPVALEEHFRDDDEGPVSNQGYMPYLNKFILEKVQGNFDKVEFNRMCWTLCAKKNLSKSPLLISDEDAFKVWVIFNFLSEDKYPLIIVPEEIEYLLKKLTEAMGAGWQQEQFDLYKIALNTSREGLSAWELIDLIGSGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMLKKGHKRKNWTERWFVLKPNIISYYVSEDLKDKKGDIILDGNCCVEPLPDKDGKKCLFLIKCLDKSFEISASDKKKKQEWIQAIQTTVSLLRAGSPPPHKEARQKRKELRQKLLAEQEELERQMKELQTANENKQKELETVRKQLEAAAARAAEEEKKRLQTQVELQDRFSLELEREKMVRQKMEEQVAQKSSELEQYLQRVRELEEMYKQLQEALEVEKQARQDEETVRKLQARLLEEESAKRAELEKWHLQQQQTIQMTEAEKQELENQRMIKEQALQVAMQQLEQLELERKEALEQYEEVKKKLETAANNTRSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEQRQKSWKGKKASSE", "length": 586, "header": "tr|F1N8E4-1|A0A8V0ZNS0_CHICK Computationally mapped isoform of Switch-associated protein 70 OS=Gallus gallus OX=9031 GN=SWAP70 PE=4 SV=3 CANONICAL=A0A8V0ZNS0-1" }, "locus": { "chromosome": "5", "start_pos": 8981929, "end_pos": 8950016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051169.1", "url": "https://www.ensembl.org/id/ENSGALT00010051169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030361.1", "url": "https://www.ensembl.org/id/ENSGALP00010030361.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423044", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423044", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QVQ9-1", "protein_name": "Switch-associated protein 70", "gene_name": "SWAP70", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGVLKDELLKAIWHAFTALDLDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDDEGPVSNQGYMPYLNKFILEKIEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKDGLSAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIISYYVSEDLKDKKGDILLDENCCVESLPDRDGKKCLFLIKCFDKTFEISASDKKKKQEWIQAIQSTIHLLKLGSPPPHKEARQRRKELRKKLLAEQEELERQMKELQVANENKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIRTTEAEKQELENQRVIKEQALQEAMEQLQQLELERKQALEQYEGVKKKLELATNKTKSWKDKVAQHEGLIRLIEPGSKNPHLITNWGPAAFTQAELEEREKSWKGKKTTE", "length": 527 }, "evidence": [ { "id": "A0A8V0ZNS0", "url": "https://omabrowser.org/oma/group/A0A8V0ZNS0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LRV2-1", "protein_name": "Switch-associated protein 70", "gene_name": "Swap70", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGLKDELLKAIWHAFTALDLDRSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDDEGPVSNQGYMPYLNKFILEKVQDNFDKIEFNRMCWTLCVKKNLTKSPLLITEDDAFKVWVIFNFLSEDKYPLIIVPEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDNKDGLSAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHKRKNWTERWFVLKPNIISYYVSEDLKDKKGDIMLDENCCVESLPDKDGKKCLFLIKCFDKTFEISASDKKKKQEWIQAIHSTIHLLKLGSPPPHKEARQRRKELRRKLLAEQEELERQMKELQAANENKQQELESVRKKLEEAASRAADEEKKRLQTQVELQTRFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLAQQQAIQTTEAEKQELEQQRVLKEQALQEAMAQLEQLELERKQALEQYEGVKRKLEMATNTTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTQAELEEREKSWKEKKTTD", "length": 585 }, "evidence": [ { "id": "A0A8V0ZNS0", "url": "https://omabrowser.org/oma/group/A0A8V0ZNS0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LYE0-1", "protein_name": "Switch-associated protein 70", "gene_name": "swap70b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGLRDELLKAIWHAFTALDVDKSGKVSKSQLKVLSHNLCTVMKIPHDPVALEEHFRDDDEGPVSNQGYMPYLNRFILDKVQDNFDRIDFNRMCWTLCARKNLNRNHLLISDDDAFKIWCIFNFLSEDKYPLVMVSEEIEYFLRKLTEAMGGSWIEEKFEQYKLQLSSKHQCLKVWELIELVGMGHFSKGMDRQTLSMGITEVFHELILDVLKQGYMMKKGHKRKNWTERWFLLKPSLISYYVSEDLTEKKGDILLDGNCCVESLPDKEGKKCLFYVKCSDKSFEISASDKKKKQEWIQAIQTCITLLKVGRPAPHHEARQKRRELRQKQQAEQEELELRMRELQMANENKQRELEAMRKKLEEAAANAADEERRRLQTQNELQDLYRLEMEKEKMVRQQMEEQVAQKSNELEQYLQRVRELENMYHSLEEALEEERQARQDEETVRKLQARLLEEEVSKRAELEEIHLYQQQTISQTQAEKQELERERLAKESALESAMQQLHQLEADRQGALEQYQEVMKKLSDAANNTKSWKDKVAQHEGLIRLIQPGPKYPQKITNWGPAAFTDAELNLREKDWQEKKNRPATPQ", "length": 588 }, "evidence": [ { "id": "A0A8V0ZNS0", "url": "https://omabrowser.org/oma/group/A0A8V0ZNS0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6A028-1", "protein_name": "Switch-associated protein 70", "gene_name": "Swap70", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGLKDELLKAIWHAFTALDLDRSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDDEGPVSNQGYMPYLNKFILEKVQDNFDKIEFNRMCWTLCVKKNLTKSPLLITEDDAFKVWVIFNFLSEDKYPLIIVPEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDNKDGLSAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHKRKNWTERWFVLKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLIKCFDKTFEISASDKKKKQEWIQAIYSTIHLLKLGSPPPHKEARQRRKELRRKLLAEQEELERQMKELQAANENKQQELESVRKKLEEAASRAADEEKKRLQTQVELQTRFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELEQQRVMKEQALQEAMAQLEQLELERKQALEQYEGVKKKLEMATHMTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTQAELEEREKSWKEKKTTE", "length": 585 }, "evidence": [ { "id": "A0A8V0ZNS0", "url": "https://omabrowser.org/oma/group/A0A8V0ZNS0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UH65-1", "protein_name": "Switch-associated protein 70", "gene_name": "SWAP70", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDDEGPVSNQGYMPYLNRFILEKVQDNFDKIEFNRMCWTLCVKKNLTKNPLLITEEDAFKIWVIFNFLSEDKYPLIIVSEEIEYLLKKLTEAMGGGWQQEQFEHYKINFDDSKNGLSAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQAIHSTIHLLKLGSPPPHKEARQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLEQLELERKQALEQYEEVKKKLEMATNKTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE", "length": 585 }, "evidence": [ { "id": "A0A8V0ZNS0", "url": "https://omabrowser.org/oma/group/A0A8V0ZNS0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of actin filament depolymerization", "id": "GO:0030835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030835", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "positive regulation of actin filament bundle assembly", "id": "GO:0032233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "negative regulation of cell-cell adhesion mediated by integrin", "id": "GO:0033633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033633", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" }, { "name": "positive regulation of mast cell chemotaxis", "id": "GO:0060754", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060754", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS0" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZN90-1", "uniprot_ac": "A0A8V0ZN90", "uniprot_id": "A0A8V0ZN90_CHICK", "mass": { "chemical_mass": 96071.0, "monoisotopic_mass": 96071.0 }, "refseq": { "ac": "XP_025007723", "name": "von Willebrand factor A domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007723" }, "gene_names": [ { "name": "VWA2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZN90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90" } ] }, { "name": "VWA2", "type": "synonym", "evidence": [ { "id": "XP_025007723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007723" } ] } ], "protein_names": [ { "name": "von Willebrand factor A domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZN90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90/entry#names_and_taxonomy" } ] }, { "name": "A domain-containing protein similar to matrilin and collagen", "type": "synonym", "evidence": [ { "id": "A0A8V0ZN90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90/entry#names_and_taxonomy" } ] }, { "name": "von Willebrand factor A domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025007723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007723" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025007723.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025007723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007723" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VWA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90", "locus": { "chromosome": "6", "start_pos": 28540442, "end_pos": 28520999, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022425", "url": "https://www.ensembl.org/id/ENSGALG00010022425" } ] } } ], "crossref": [ { "id": "A0A8V0ZN90", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZN90", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00053", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00053", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01472", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01472", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423907", "url": "https://www.ncbi.nlm.nih.gov/gene/423907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423907", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423907", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MWCSAAM", "url": "https://omabrowser.org/oma/group/MWCSAAM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHX5", "url": "https://www.orthodb.org/?gene=A0A8V0ZHX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN85", "url": "https://www.orthodb.org/?gene=A0A8V0ZN85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN90", "url": "https://www.orthodb.org/?gene=A0A8V0ZN90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVN6", "url": "https://www.orthodb.org/?gene=A0A8V0ZVN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025007723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007723", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHX5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQYKGTAPLHPHFLDHVLRVAKDHLPPRSKRRLRAQRPSAARLCPTATCGAVRAEAELRSRLLLLLLLPAEPPRVAHSRAWERRRFVTMNLLPLESLCVFLLPQVWLALGMQEIHADQETIGKISAAGQLMWCSASVDILFLLDGSYSIGRGSFERSKHFAGKLCDALDIHPGRVRVGMVQFSSAPHLEFSLDSYLTKQEVKERIKRTAFRGGSTETGRALKYILHKGFPGGRNLTVPKILIIISDGKSQGSTAVPAMQVKERGTTVFAVGIKFPRWEELHAVASEPTEQHVLFAGDASDAANGLYSALSSSICSITTPGCKVESFPCERRTLETEKELAGSYVCWKGSKQQNVMHASLCPFYRVKRVSVKHPSRCFRTVCTDPCDSQPCQNGGTCVPEGLDKYHCLCPVGYGGGTHCAPKLSLECGVDLLFLMDSSAGVTLEGFLRYKAFLKRFLQAVMGRDSPANVGVAQYDTSIRIPIEVGQHKDVFGLMKSIDALNFSGGGTLTGRALWYVAQHGFRRTPVFADVLDDLPRVVVLLTDSKSQDPVAEAAKYARDRDLLLIGVGSSFVRAELAEVTGNPKQTVVYSDPQDLFNRIPELQRRICSVNSPEGCQVQSLDLVFAVDASAGVGLANFLQLRDFVRSSSWQFTINRDVTQIALVAYGSRAHTVFALDTYTNNSALVQAINQMPFLGDVASASSALLHIHSDVMTVQKGARPGVSKVVVLLTNGGGMEDAAAPARQLRDNGVTVFVVVIGDAERDTLLRVAGSPSYLVHISSYEDLQRYQDLITERICEEAKSPVNLCKPNPCMNQGVCILRPGSYWCECHGWEGPHCESRVPRGDSPRSPVLPTDSHVQQIPGTFQHFSGAHRHPKRS", "length": 876, "header": "tr|A0A8V0ZN90-1|A0A8V0ZN90_CHICK Isoform 1 of von Willebrand factor A domain-containing protein 2 OS=Gallus gallus OX=9031 GN=VWA2 PE=4 SV=1 CANONICAL=A0A8V0ZN90-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZHX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90/entry#A0A8V0ZHX5-1", "sequence": { "sequence": "MNLLPLESLCVFLLPQVWLALGMQEIHADQETIGKISAAGQLMWCSASVDILFLLDGSYSIGRGSFERSKHFAGKLCDALDIHPGRVRVGMVQFSSAPHLEFSLDSYLTKQEVKERIKRTAFRGGSTETGRALKYILHKGFPGGRNLTVPKILIIISDGKSQGSTAVPAMQVKERGTTVFAVGIKFPRWEELHAVASEPTEQHVLFAGDASDAANGLYSALSSSICSITTPGCKVESFPCERRTLETEKELAGSYVCWKGSKQQNVMHASLCPFYRVKRVSVKHPSRCFRTVCTDPCDSQPCQNGGTCVPEGLDKYHCLCPVGYGGGTHCAPKLSLECGVDLLFLMDSSAGVTLEGFLRYKAFLKRFLQAVMGRDSPANVGVAQYDTSIRIPIEVGQHKDVFGLMKSIDALNFSGGGTLTGRALWYVAQHGFRRTPVFADVLDDLPRVVVLLTDSKSQDPVAEAAKYARDRDLLLIGVGSSFVRAELAEVTGNPKQTVVYSDPQDLFNRIPELQRRICSVNSPEGCQVQSLDLVFAVDASAGVGLANFLQLRDFVRSSSWQFTINRDVTQIALVAYGSRAHTVFALDTYTNNSALVQAINQMPFLGDVASASSALLHIHSDVMTVQKGARPGVSKVVVLLTNGGGMEDAAAPARQLRDNGVTVFVVVIGDAERDTLLRVAGSPSYLVHISSYEDLQRYQDLITERICEEAKSPVNLCKPNPCMNQGVCILRPGSYWCECHGWEGPHCESRVPRGFLQEPSLVTGQVLTAGESLFLQQGTGI", "length": 781, "header": "tr|A0A8V0ZHX5-1|A0A8V0ZN90_CHICK Computationally mapped isoform of von Willebrand factor A domain-containing protein 2 OS=Gallus gallus OX=9031 GN=VWA2 PE=4 SV=1 CANONICAL=A0A8V0ZN90-1" }, "locus": { "chromosome": "6", "start_pos": 28540439, "end_pos": 28524333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054519.1", "url": "https://www.ensembl.org/id/ENSGALT00010054519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032932.1", "url": "https://www.ensembl.org/id/ENSGALP00010032932.1" } ] } }, { "isoform_ac": "A0A8V0ZN85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90/entry#A0A8V0ZN85-1", "sequence": { "sequence": "MSGESLANLMWCSASVDILFLLDGSYSIGRGSFERSKHFAGKLCDALDIHPGRVRVGMVQFSSAPHLEFSLDSYLTKQEVKERIKRTAFRGGSTETGRALKYILHKGFPGGRNLTVPKILIIISDGKSQGSTAVPAMQVKERGTTVFAVGIKFPRWEELHAVASEPTEQHVLFAGDASDAANGLYSALSSSICSITTPGCKVESFPCERRTLETEKELAGSYVCWKGSKQQNVMHASLCPFYRVKRVSVKHPSRCFRTVCTDPCDSQPCQNGGTCVPEGLDKYHCLCPVGYGGGTHCAPKLSLECGVDLLFLMDSSAGVTLEGFLRYKAFLKRFLQAVMGRDSPANVGVAQYDTSIRIPIEVGQHKDVFGLMKSIDALNFSGGGTLTGRALWYVAQHGFRRTPVFADVLDDLPRVVVLLTDSKSQDPVAEAAKYARDRDLLLIGVGSSFVRAELAEVTGNPKQTVVYSDPQDLFNRIPELQRRICSVNSPEGCQVQSLDLVFAVDASAGVGLANFLQLRDFVRSSSWQFTINRDVTQIALVAYGSRAHTVFALDTYTNNSALVQAINQMPFLGDVASASSALLHIHSDVMTVQKGARPGVSKVVVLLTNGGGMEDAAAPARQLRDNGVTVFVVVIGDAERDTLLRVAGSPSYLVHISSYEDLQRYQDLITERICEEAKSPVNLCKPNPCMNQGVCILRPGSYWCECHGWEGPHCESRVPRGDSPRSPVLPTDSHVQQIPGTFQHFSGAHRHPKRS", "length": 755, "header": "tr|A0A8V0ZN85-1|A0A8V0ZN85_CHICK Computationally mapped isoform of von Willebrand factor A domain-containing protein 2 OS=Gallus gallus OX=9031 GN=VWA2 PE=4 SV=1 CANONICAL=A0A8V0ZN90-1" }, "locus": { "chromosome": "6", "start_pos": 28538157, "end_pos": 28525317, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054501.1", "url": "https://www.ensembl.org/id/ENSGALT00010054501.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032919.1", "url": "https://www.ensembl.org/id/ENSGALP00010032919.1" } ] } }, { "isoform_ac": "A0A8V0ZN90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90/entry#A0A8V0ZN90-1", "sequence": { "sequence": "MQYKGTAPLHPHFLDHVLRVAKDHLPPRSKRRLRAQRPSAARLCPTATCGAVRAEAELRSRLLLLLLLPAEPPRVAHSRAWERRRFVTMNLLPLESLCVFLLPQVWLALGMQEIHADQETIGKISAAGQLMWCSASVDILFLLDGSYSIGRGSFERSKHFAGKLCDALDIHPGRVRVGMVQFSSAPHLEFSLDSYLTKQEVKERIKRTAFRGGSTETGRALKYILHKGFPGGRNLTVPKILIIISDGKSQGSTAVPAMQVKERGTTVFAVGIKFPRWEELHAVASEPTEQHVLFAGDASDAANGLYSALSSSICSITTPGCKVESFPCERRTLETEKELAGSYVCWKGSKQQNVMHASLCPFYRVKRVSVKHPSRCFRTVCTDPCDSQPCQNGGTCVPEGLDKYHCLCPVGYGGGTHCAPKLSLECGVDLLFLMDSSAGVTLEGFLRYKAFLKRFLQAVMGRDSPANVGVAQYDTSIRIPIEVGQHKDVFGLMKSIDALNFSGGGTLTGRALWYVAQHGFRRTPVFADVLDDLPRVVVLLTDSKSQDPVAEAAKYARDRDLLLIGVGSSFVRAELAEVTGNPKQTVVYSDPQDLFNRIPELQRRICSVNSPEGCQVQSLDLVFAVDASAGVGLANFLQLRDFVRSSSWQFTINRDVTQIALVAYGSRAHTVFALDTYTNNSALVQAINQMPFLGDVASASSALLHIHSDVMTVQKGARPGVSKVVVLLTNGGGMEDAAAPARQLRDNGVTVFVVVIGDAERDTLLRVAGSPSYLVHISSYEDLQRYQDLITERICEEAKSPVNLCKPNPCMNQGVCILRPGSYWCECHGWEGPHCESRVPRGDSPRSPVLPTDSHVQQIPGTFQHFSGAHRHPKRS", "length": 876, "header": "tr|A0A8V0ZN90-1|A0A8V0ZN90_CHICK Isoform 1 of von Willebrand factor A domain-containing protein 2 OS=Gallus gallus OX=9031 GN=VWA2 PE=4 SV=1 CANONICAL=A0A8V0ZN90-1" }, "locus": { "chromosome": "6", "start_pos": 28538157, "end_pos": 28521169, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054508.1", "url": "https://www.ensembl.org/id/ENSGALT00010054508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032924.1", "url": "https://www.ensembl.org/id/ENSGALP00010032924.1" } ] } }, { "isoform_ac": "A0A8V0ZVN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90/entry#A0A8V0ZVN6-1", "sequence": { "sequence": "MNLLPLESLCVFLLPQVWLALGMQEIHADQETIGKISAAGQLMWCSASVDILFLLDGSYSIGRGSFERSKHFAGKLCDALDIHPGRVRVGMVQFSSAPHLEFSLDSYLTKQEVKERIKRTAFRGGSTETGRALKYILHKGFPGGRNLTVPKILIIISDGKSQGSTAVPAMQVKERGTTVFAVGIKFPRWEELHAVASEPTEQHVLFAGDASDAANGLYSALSSSICSITTPGCKVESFPCERRTLETEKELAGSYVCWKGSKQQNVMHASLCPFYRVKRVSVKHPSRCFRTVCTDPCDSQPCQNGGTCVPEGLDKYHCLCPVGYGGGTHCAPKLSLECGVDLLFLMDSSAGVTLEGFLRYKAFLKRFLQAVMGRDSPANVGVAQYDTSIRIPIEVGQHKDVFGLMKSIDALNFSGGGTLTGRALWYVAQHGFRRTPVFADVLDDLPRVVVLLTDSKSQDPVAEAAKYARDRDLLLIGVGSSFVRAELAEVTGNPKQTVVYSDPQDLFNRIPELQRRICSVNSPEGCQVQSLDLVFAVDASAGVGLANFLQLRDFVRSSSWQFTINRDVTQIALVAYGSRAHTVFALDTYTNNSALVQAINQMPFLGDVASASSALLHIHSDVMTVQKGARPGVSKVVVLLTNGGGMEDAAAPARQLRDNGVTVFVVVIGDAERDTLLRVAGSPSYLVHISSYEDLQRYQDLITERICEGVPRGDSPRSPVLPTDSHVQQIPGTFQHFSGAHRHPKRS", "length": 747, "header": "tr|A0A8V0ZVN6-1|A0A8V0ZN90_CHICK Computationally mapped isoform of von Willebrand factor A domain-containing protein 2 OS=Gallus gallus OX=9031 GN=VWA2 PE=4 SV=1 CANONICAL=A0A8V0ZN90-1" }, "locus": { "chromosome": "6", "start_pos": 28538157, "end_pos": 28524333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054513.1", "url": "https://www.ensembl.org/id/ENSGALT00010054513.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032928.1", "url": "https://www.ensembl.org/id/ENSGALP00010032928.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423907", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423907", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FQB7-1", "protein_name": "von Willebrand factor A domain-containing protein 2", "gene_name": "VWA2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPSFLLEAICIFLFAGAPPSLSLQEIHVSKEIVRKISAASKMMWCSAAVDILFLIDGSHSIGKGSFERSKHFAITVCEALDVDPARVRVGAVQFGSTPRLEFPLDAFSTQQEVKAEIRRMAFKGGRTETGLALKYLLRKGFPGGRNASVPQVLLIVTDGRSQGHVAEPAEQLKQRDVTVFAVGVRFPRWEELHILASEPTEQHVLMAEQVEDAANGLFSSLSSSAICTITSPDCKVQPHPCERKTLETVRELAGHAPCWRGSRGTDAVLAALCPFSSWKRVFLSHPATCYRTTCPGPCDSQPCQNGGTCVPEGPDRYHCLCPPAFRGEADCAPKLSVECRVDILFLLASSAAATPEGFQRAKAFVKRFAQAVLGEASRARVGVAHYNSKLAVAVPVGEYLDVPDLVRSLDGVPFGGGPTLTGRALQQVAERGFGSAAWTGQDRPRRVVVLMTEARSQDEVAGPALFARARELLLLGVGSEAVQAELEEITGSPERVMVYTGPQDLFNQIPKLRGHLCSQPHPGCRARPLDLVFMLDASASVGPENFARMQSFLRSCTLQFDVNPDVMQMGLVVYGGQVQTAFGLDTHTTRATVLRALSQAPYLGGAGSAGTALLHIYDKVMTVQMGARPGVPKVVIVVTGGQGVEDAAVPAEKLRDNGVSVLVVGVGPVLREALRRLAGPRDSLIHVAAYEDLSHHQDTLIEWICREAKQPVNLCKPNPCMNEGTCILRNGSYRCECRDGREGPHCESWALRCPE", "length": 755 }, "evidence": [ { "id": "A0A8V0ZN90", "url": "https://omabrowser.org/oma/group/A0A8V0ZN90/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0LED2-1", "protein_name": "von Willebrand factor A domain-containing protein 2", "gene_name": "Vwa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPKPFFTVTLPCVIGGCSLARGSSSLLVCSVPDFASPSMFSLWRSNNMPPYLFLPAIYTLLFSRVSLSSSLQEVHVSRETTGKIAVASKLIWCSAAVDILFLLDGSHSIGKGSFERSKRFATALCDALDISPGRVRVGALQFGSTPHLEFPLDAFSTRQEVKEIIKKLVFKGGRTETGLALKHLLRGLPGGRNGSVPQILIIITDGKSQGHVALPAKQLKERGIVVFAVGVRFPRWDELLTLASEPKEQHVLLAEQVEDATNGLLSTLSSSLLCTTADPDCRVEAYPCERRTLETMRELASNALCWRGSRQADTVLAVPCPFYSWKRVFQTHPANCYRTICPGPCDSQPCQNGGTCIPEGVDRYHCLCPLAFGGEVNCAPKLSLECRIDVLFLLDSSAGTTPEGFRQAKAFVKRFVQAVLSEDSRARVGVASYSRDLMVAVPVGEYQHVPDLVRILDSIPFSGGPTLTGSALLQVTEHGFGSASRTGQDRPRRVVVLLTESHAQDEVAGPADHARARELLLLGMGNELMRAELERITGSRKHVIIHTDPRDMFSQIPELQRRLCSQPRPGCQAQSLDLVFLLDASASVGGENFAQMQSFIRKCTLRFDVNPDVTQVGLVVYGNQVQTAFGLDTHPTRASVLRAMSQAPYLGGVGSAGTALLHIEDKVMTVQRGARPGVPKAVVMLTGGSGAEDAAVPAQKLRDNGISVLVMSVGAVLKEAVRRLAGPRDYLIHVAAYTDLRYHQDTLIEWLCREAKRPVSLCKPSPCMNEGTCILKNGSYRCECWGGWEGPHCENRVLRGDAPMAHSFRREPTGRQQPTPSQQAPKHVGV", "length": 831 }, "evidence": [ { "id": "A0A8V0ZN90", "url": "https://omabrowser.org/oma/group/A0A8V0ZN90/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5GFL6-1", "protein_name": "von Willebrand factor A domain-containing protein 2", "gene_name": "VWA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPFLLLEAVCVFLFSRVPPSLPLQEVHVSKETIGKISAASKMMWCSAAVDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPLDSFSTQQEVKARIKRMVFKGGRTETELALKYLLHRGLPGGRNASVPQILIIVTDGKSQGDVALPSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLLAEQVEDATNGLFSTLSSSAICSSATPDCRVEAHPCEHRTLEMVREFAGNAPCWRGSRRTLAVLAAHCPFYSWKRVFLTHPATCYRTTCPGPCDSQPCQNGGTCVPEGLDGYQCLCPLAFGGEANCALKLSLECRVDLLFLLDSSAGTTLDGFLRAKVFVKRFVRAVLSEDSRARVGVATYSRELLVAVPVGEYQDVPDLVWSLDGIPFRGGPTLTGSALRQAAERGFGSATRTGQDRPRRVVVLLTESHSEDEVAGPARHARARELLLLGVGSEAVRAELEEITGSPKHVMVYSDPQDLFNQIPELQGKLCSRQRPGCRTQALDLVFMLDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVGLVVYGSQVQTAFGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARPGVPKAVVVLTGGRGAEDAAVPAQKLRNNGISVLVVGVGPVLSEGLRRLAGPRDSLIHVAAYADLRYHQDVLIEWLCGEAKQPVNLCKPSPCMNEGSCVLQNGSYRCKCRDGWEGPHCENRFLRRP", "length": 755 }, "evidence": [ { "id": "A0A8V0ZN90", "url": "https://omabrowser.org/oma/group/A0A8V0ZN90/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q70UZ7-1", "protein_name": "von Willebrand factor A domain-containing protein 2", "gene_name": "Vwa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPLLLLPAIYMLLFFRVSPTISLQEVHVNRETMGKIAVASKLMWCSAAVDILFLLDGSHSIGKGSFERSKRFAIAACDALDISPGRVRVGALQFGSTPHLEFPLDSFSTRQEVKESIKGIVFKGGRTETGLALKRLSRGFPGGRNGSVPQILIIVTDGKSQGPVALPAKQLRERGIVVFAVGVRFPRWDELLTLASEPKDRHVLLAEQVEDATNGLLSTLSSSALCTTADPDCRVEPHPCERRTLETVRELAGNALCWRGSRQADTVLALPCPFYSWKRVFQTHPANCYRTICPGPCDSQPCQNGGTCIPEGVDRYHCLCPLAFGGEVNCAPKLSLECRIDVLFLLDSSAGTTLGGFRRAKAFVKRFVQAVLREDSRARVGIASYGRNLMVAVPVGEYQHVPDLIRSLDSIPFSGGPTLTGSALLQVAEHGFGSASRTGQDRPRRVVVLLTESRSQDEVSGPAAHARARELLLLGVGSEILQAELVKITGSPKHVMVHTDPQDLFSQIPELQRRLCSQPRPGCQAQSLDLVFLLDASASVGRENFAQMQSFIRKCTLRFDVNPDVTQVGLVVYGSRVQTAFGLDTHPTRAAVLRAMSQAPYLGGVGSAGTALLHIEDKVMTVQRGARPGVPKAVVMLTGGSGAEDAAVPAQKLRGNGISVLVMSVGAVLREAVRRLAGPRDSLIHVAAYTDLPYHQDMLIEWLCREARLPVNLCKPSPCMNEGTCVLKNGSYRCECRGGWEGPHCENRILRGDAPMARSFHQEPAGLQGPTPSQQAPKHLRIGKALSSAK", "length": 791 }, "evidence": [ { "id": "A0A8V0ZN90", "url": "https://omabrowser.org/oma/group/A0A8V0ZN90/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "calcium-independent cell-matrix adhesion", "id": "GO:0007161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90" } ], "pmid": "" }, { "name": "regulation of insulin receptor signaling pathway", "id": "GO:0046626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046626", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN90", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZN90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 382, "end_pos": 419, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZN90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN90" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 309, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 679, "end_pos": 681 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQQ5-1", "uniprot_ac": "A0A8V0ZQQ5", "uniprot_id": "A0A8V0ZQQ5_CHICK", "mass": { "chemical_mass": 65041.0, "monoisotopic_mass": 65041.0 }, "refseq": {}, "gene_names": [ { "name": "C12orf4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5" } ] } ], "protein_names": [ { "name": "FERRY endosomal RAB5 effector complex subunit 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C12orf4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZQQ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI16", "url": "https://www.orthodb.org/?gene=A0A8V0ZI16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNC6", "url": "https://www.orthodb.org/?gene=A0A8V0ZNC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ77", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQP9", "url": "https://www.orthodb.org/?gene=A0A8V0ZQP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQQ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZQQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVS3", "url": "https://www.orthodb.org/?gene=A0A8V0ZVS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVS8", "url": "https://www.orthodb.org/?gene=A0A8V0ZVS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16525", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16525", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16525:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16525:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10154", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10154", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZI16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI16-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ77", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVS8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPNRGKTCAGERDYVYMLSAGNQHFVLTVPLKFPVQENISHLHGRLMLLHNLPCFVENDLKQSLNKFIEDETIKGYDREAEMALEAVKSGEVDINQLAETWAKAYKETTLEYAKPEENSWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELISERDVELKKLQERQGAEMDKVMQELGKSLTDQDVNSLAARHFESQQDLENKWTNELKQSTAIQKQEYQEWVIKLHHDLKNPNNSSISDEIKVQPSQLRDSVEGNGRIYEEQSLLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRNHRNGVKLHRLQTAMSLYSTSLCGLVLLVDNRISSYSGIKRDFATVCQECTDFHFPGIQEQLEIVQKVVLKARAQRSNKAKRHHGNKDSGIEDKSKNIERNQSNILQGEFYITRHSNLSEIHVAFHLCVDDNVRSGNITARDPAIMGLRNILKVCCTHDITTISIPLLLVHDMSEHSYGEAGSSWFRQIYSSLHKKLVGWLGPGIDLNSAVNRSVLGPVLFNIFIDDLDKGIECSLNFADDTKVGVSVNLFEIKKALQEDLDRMDR", "length": 569, "header": "tr|A0A8V0ZQQ5-1|A0A8V0ZQQ5_CHICK Isoform 1 of FERRY endosomal RAB5 effector complex subunit 3 OS=Gallus gallus OX=9031 GN=C12orf4 PE=1 SV=1 CANONICAL=A0A8V0ZQQ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZI16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5/entry#A0A8V0ZI16-1", "sequence": { "sequence": "MKPNRGKTCAGERDYVYMLSAGNQHFVLTVPLKFPVQENISHLHGRLMLLHNLPCFVENDLKQSLNKFIEDETIKGYDREAEMALEAVKSGEVDINQLAETWAKAYKETTLEYAKPEENSWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELISERDVELKKLQERQGAEMDKVMQELGKSLTDQDVNSLAARHFESQQDLENKWTNELKQSTAIQKQEYQEWVIKLHHDLKNPNNSSISDEIKVQPSQLRDSVEGNGRIYEEQSLLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRNHRNGVKLHRLQTAMSLYSTSLCGLVLLVDNRISSYSGIKRDFATVCQECTDFHFPGIQEQLEIVQKVVLKARAQRSNKAKRHHGNKDSGIEDKSKNIERNQSNILQGEFYITRHSNLSEIHVAFHLCVDDNVRSGNITARDPAIMGLRNILKVCCTHDITTISIPLLLVHDMSEHSYGEAGSSWFRQIYCLVGWRNFSNCTILGTTDNF", "length": 513, "header": "tr|A0A8V0ZI16-1|A0A8V0ZQQ5_CHICK Computationally mapped isoform of FERRY endosomal RAB5 effector complex subunit 3 OS=Gallus gallus OX=9031 GN=C12orf4 PE=1 SV=1 CANONICAL=A0A8V0ZQQ5-1" }, "locus": { "chromosome": "1", "start_pos": 73489711, "end_pos": 73465483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054591.1", "url": "https://www.ensembl.org/id/ENSGALT00010054591.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032977.1", "url": "https://www.ensembl.org/id/ENSGALP00010032977.1" } ] } }, { "isoform_ac": "A0A8V0ZNC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5/entry#A0A8V0ZNC6-1", "sequence": { "sequence": "MQSLNKFIEDETIKGYDREAEMALEAVKSGEVDINQLAETWAKAYKETTLEYAKPEENSWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELISERDVELKKLQERQGAEMDKVMQELGKSLTDQDVNSLAARHFESQQVN", "length": 143, "header": "tr|A0A8V0ZNC6-1|A0A8V0ZNC6_CHICK Computationally mapped isoform of FERRY endosomal RAB5 effector complex subunit 3 OS=Gallus gallus OX=9031 GN=C12orf4 PE=1 SV=1 CANONICAL=A0A8V0ZQQ5-1" }, "locus": { "chromosome": "1", "start_pos": 73470464, "end_pos": 73465891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054569.1", "url": "https://www.ensembl.org/id/ENSGALT00010054569.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032959.1", "url": "https://www.ensembl.org/id/ENSGALP00010032959.1" } ] } }, { "isoform_ac": "A0A8V0ZQ77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5/entry#A0A8V0ZQ77-1", "sequence": { "sequence": "MGIEDRNELKKMKPNRGKTCAGERDYVYMLSAGNQHFVLTVPLKFPVQENISHLHGRLMLLHNLPCFVENDLKQSLNKFIEDETIKGYDREAEMALEAVKSGEVDINQLAETWAKAYKETTLEYAKPEENSWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELISERDVELKKLQERQGAEMDKVMQELGKSLTDQDVNSLAARHFESQQDLENKWTNELKQSTAIQKQEYQEWVIKLHHDLKNPNNSSISDEIKVQPSQLRDSVEGNGRIYEEQSLLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRNHRNGVKLHRLQTAMSLYSTSLCGLVLLVDNRISSYSGIKRDFATVCQECTDFHFPGIQEQLEIVQKVVLKARAQRSNKAKRHHGNKDSGIEDKSKNIERNQSNILQGEFYITRHSNLSEIHVAFHLCVDDNVRSGNITARDPAIMGLRNILKVCCTHDITTISIPLLLVHDMSEEMTIPWCLKRAELVFKCVKGFMMEMASWDGGISRTVQFLVPQTISEELFYQLSNMLPQIFRVSSTLTLTSKH", "length": 561, "header": "tr|A0A8V0ZQ77-1|A0A8V0ZQ77_CHICK Computationally mapped isoform of FERRY endosomal RAB5 effector complex subunit 3 OS=Gallus gallus OX=9031 GN=C12orf4 PE=1 SV=1 CANONICAL=A0A8V0ZQQ5-1" }, "locus": { "chromosome": "1", "start_pos": 73489793, "end_pos": 73463982, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054602.1", "url": "https://www.ensembl.org/id/ENSGALT00010054602.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032986.1", "url": "https://www.ensembl.org/id/ENSGALP00010032986.1" } ] } }, { "isoform_ac": "A0A8V0ZQP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5/entry#A0A8V0ZQP9-1", "sequence": { "sequence": "MLLHNLPCFVENDLKQSLNKFIEDETIKGYDREAEMALEAVKSGEVDINQLAETWAKAYKETTLEYAKPEENSWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELISERDVELKKLQERQGAEMDKVMQELGKSLTDQDVNSLAARHFESQQDLENKWTNELKQSTAIQKQEYQEWVIKLHHDLKNPNNSSIRLSKRSVWNMKEKR", "length": 209, "header": "tr|A0A8V0ZQP9-1|A0A8V0ZQP9_CHICK Computationally mapped isoform of FERRY endosomal RAB5 effector complex subunit 3 OS=Gallus gallus OX=9031 GN=C12orf4 PE=1 SV=1 CANONICAL=A0A8V0ZQQ5-1" }, "locus": { "chromosome": "1", "start_pos": 73471438, "end_pos": 73465624, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054571.1", "url": "https://www.ensembl.org/id/ENSGALT00010054571.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032960.1", "url": "https://www.ensembl.org/id/ENSGALP00010032960.1" } ] } }, { "isoform_ac": "A0A8V0ZQQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5/entry#A0A8V0ZQQ5-1", "sequence": { "sequence": "MKPNRGKTCAGERDYVYMLSAGNQHFVLTVPLKFPVQENISHLHGRLMLLHNLPCFVENDLKQSLNKFIEDETIKGYDREAEMALEAVKSGEVDINQLAETWAKAYKETTLEYAKPEENSWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELISERDVELKKLQERQGAEMDKVMQELGKSLTDQDVNSLAARHFESQQDLENKWTNELKQSTAIQKQEYQEWVIKLHHDLKNPNNSSISDEIKVQPSQLRDSVEGNGRIYEEQSLLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRNHRNGVKLHRLQTAMSLYSTSLCGLVLLVDNRISSYSGIKRDFATVCQECTDFHFPGIQEQLEIVQKVVLKARAQRSNKAKRHHGNKDSGIEDKSKNIERNQSNILQGEFYITRHSNLSEIHVAFHLCVDDNVRSGNITARDPAIMGLRNILKVCCTHDITTISIPLLLVHDMSEHSYGEAGSSWFRQIYSSLHKKLVGWLGPGIDLNSAVNRSVLGPVLFNIFIDDLDKGIECSLNFADDTKVGVSVNLFEIKKALQEDLDRMDR", "length": 569, "header": "tr|A0A8V0ZQQ5-1|A0A8V0ZQQ5_CHICK Isoform 1 of FERRY endosomal RAB5 effector complex subunit 3 OS=Gallus gallus OX=9031 GN=C12orf4 PE=1 SV=1 CANONICAL=A0A8V0ZQQ5-1" }, "locus": { "chromosome": "1", "start_pos": 73483247, "end_pos": 73465483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054576.1", "url": "https://www.ensembl.org/id/ENSGALT00010054576.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032965.1", "url": "https://www.ensembl.org/id/ENSGALP00010032965.1" } ] } }, { "isoform_ac": "A0A8V0ZVS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5/entry#A0A8V0ZVS3-1", "sequence": { "sequence": "MKPNRGKTCAGERDYVYMLSAGNQHFVLTVPLKFPVQENISHLHGRLMLLHNLPCFVENDLKQSLNKFIEDETIKGYDREAEMALEAVKSGEVDINQLAETWAKAYKETTLEYAKPEENSWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELISERDVELKKLQERQGAEMDKVMQELGKSLTDQDVNSLAARHFESQQDLENKWTNELKQSTAIQKQEYQEWVIKLHHDLKNPNNSSIRVSASLSIPMKL", "length": 254, "header": "tr|A0A8V0ZVS3-1|A0A8V0ZQQ5_CHICK Computationally mapped isoform of FERRY endosomal RAB5 effector complex subunit 3 OS=Gallus gallus OX=9031 GN=C12orf4 PE=1 SV=1 CANONICAL=A0A8V0ZQQ5-1" }, "locus": { "chromosome": "1", "start_pos": 73471705, "end_pos": 73465483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054574.1", "url": "https://www.ensembl.org/id/ENSGALT00010054574.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032963.1", "url": "https://www.ensembl.org/id/ENSGALP00010032963.1" } ] } }, { "isoform_ac": "A0A8V0ZVS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5/entry#A0A8V0ZVS8-1", "sequence": { "sequence": "MQTGCSVAWGSKTVVITFSHPLSSPLKGNELKKMKPNRGKTCAGERDYVYMLSAGNQHFVLTVPLKFPVQENISHLHGRLMLLHNLPCFVENDLKQSLNKFIEDETIKGYDREAEMALEAVKSGEVDINQLAETWAKAYKETTLEYAKPEENSWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELISERDVELKKLQERQGAEMDKVMQELGKSLTDQDVNSLAARHFESQQDLENKWTNELKQSTAIQKQEYQEWVIKLHHDLKNPNNSSISDEIKVQPSQLRDSVEGNGRIYEEQSLLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRNHRNGVKLHRLQTAMSLYSTSLCGLVLLVDNRISSYSGIKRDFATVCQECTDFHFPGIQEQLEIVQKVVLKARAQRSNKAKRHHGNKDSGIEDKSKNIERNQSNILQGEFYITRHSNLSEIHVAFHLCVDDNVRSGNITARDPAIMGLRNILKVCCTHDITTISIPLLLVHDMSEEMTIPWCLKRAELVFKCVKGMLVNVSAHF", "length": 540, "header": "tr|A0A8V0ZVS8-1|A0A8V0ZQQ5_CHICK Computationally mapped isoform of FERRY endosomal RAB5 effector complex subunit 3 OS=Gallus gallus OX=9031 GN=C12orf4 PE=1 SV=1 CANONICAL=A0A8V0ZQQ5-1" }, "locus": { "chromosome": "1", "start_pos": 73487436, "end_pos": 73463959, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054580.1", "url": "https://www.ensembl.org/id/ENSGALT00010054580.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032968.1", "url": "https://www.ensembl.org/id/ENSGALP00010032968.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5" } ], "pmid": "" }, { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of mast cell degranulation", "id": "GO:0043304", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043304", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 238, "end_pos": 240 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 404, "end_pos": 406 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 440, "end_pos": 442 }, { "start_pos": 515, "end_pos": 517 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQW6-1", "uniprot_ac": "A0A8V0ZQW6", "uniprot_id": "A0A8V0ZQW6_CHICK", "mass": { "chemical_mass": 106582.0, "monoisotopic_mass": 106582.0 }, "refseq": {}, "gene_names": [ { "name": "SART3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ] } ], "protein_names": [ { "name": "Spliceosome associated factor 3, U4/U6 recycling protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6/entry#names_and_taxonomy" } ] }, { "name": "Squamous cell carcinoma antigen recognized by T-cells 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SART3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6", "locus": { "chromosome": "15", "start_pos": 6520050, "end_pos": 6535941, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022467", "url": "https://www.ensembl.org/id/ENSGALG00010022467" } ] } } ], "crossref": [ { "id": "A0A8V0ZQW6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQW6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12391", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12391", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12392", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12392", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416890", "url": "https://www.ncbi.nlm.nih.gov/gene/416890", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034218", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034218", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416890", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416890", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWARYIL", "url": "https://omabrowser.org/oma/group/LWARYIL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI49", "url": "https://www.orthodb.org/?gene=A0A8V0ZI49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI54", "url": "https://www.orthodb.org/?gene=A0A8V0ZI54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQW6", "url": "https://www.orthodb.org/?gene=A0A8V0ZQW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17204", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17204", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17204:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17204:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZI49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI54", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFAEEGSLGVPQCYVCVRGLSGLGAASSVICRTLKLGLYKRDLIGGAAEVVGACSISLLSINAFDYNCHLDLIKLLRQEGELVKLRRARQKMSELFPLTEEIWLDWLKDEIKMASEVSEREKVYELFERAVKDYICPEIWLEYAQYSIGGIGQEGGIEKVRSIFERALTAVGLHVTKGTALWEAYREFENAILETAQPAPGSVPSPEQQQMLCSQLERIHTLFRRQLGIPLLDMEASYAEYEEWSEDPIPETTIKNYKKALQQLEKCKPYEEALLGAETPKLAEYQAYIDFEMKAGDPARIQLIYERALAENCLVPDLWARYNQYLDRQLKVKELVLSAHDRAVRNCPWTVGLWIQYLLAMERHGVDHCIISDMFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFTQDSSKELEELRSAFARAVEYLKQEVEERFSESGDPSCTIMQNWARVEARLCNNMQKARELWDNIMTKGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTLERIEGTLEDWDAAVQKTENRLARVNEQRAKAAEKEAALARQEEEKAEQRKQSRAEKKASKKAKKNRIGEKRKADDDDEGEWGQEEEEEQPSKRHKGDGDGLLLEEEMELETGLFGRSGPEKPDHPTNQKEKPSTSRKDVPKVLHDSSKDNITVFVSNLSYNMTDPEVKLKELFESCGEVSQVRPVFSNKGTFRGYCYVEFKDEKSALQALGMDRKVVEGRPMFVSPCVDKNKNPDFKVFRYSTTLEKHKLFISGLPFSCTKEELEDICKAHGNVKDIRLVTNRAGKPKGLAYVEYENEAQASQAVLKMDGLTIKEHVIKVAISNPPLRKLPDKAEAGRASQFAVPRQIYGARGKGRTQLSMMPRALQRQSNPVAKAENGMVQNSPATSSERTEEPKKMSNADFAKMLLNK", "length": 935, "header": "tr|A0A8V0ZQW6-1|A0A8V0ZQW6_CHICK Isoform 1 of Spliceosome associated factor 3, U4/U6 recycling protein OS=Gallus gallus OX=9031 GN=SART3 PE=1 SV=1 CANONICAL=A0A8V0ZQW6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZI49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6/entry#A0A8V0ZI49-1", "sequence": { "sequence": "MAAAGAEAAAAEEEKRMAEGDPESGGDSEDEGDSDSSGDGEDEEKENEAEIQRLEEQLSINAFDYNCHLDLIKLLRQEGELVKLRRARQKMSELFPLTEEIWLDWLKDEIKMASEVSEREKVYELFERAVKDYICPEIWLEYAQYSIGGIGQEGGIEKVRSIFERALTAVGLHVTKGTALWEAYREFENAILETAQPAPGSVPSPEQQQMLCSQLERIHTLFRRQLGIPLLDMEASYAEYEEWSEDPIPETTIKNYKKALQQLEKCKPYEEALLGAETPKLAEYQAYIDFEMKAGDPARIQLIYERALAENCLVPDLWARYNQYLDRQLKVKELVLSAHDRAVRNCPWTVGLWIQYLLAMERHGVDHCIISDMFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFTQDSSKELEELRSAFARAVEYLKQEVEERFSESGDPSCTIMQNWARVEARLCNNMQKARELWDNIMTKGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTLERIEGTLEDWDAAVQKTENRLARVNEQRAKAAEKEAALARQEEEKAEQRKQSRAEKKASKKAKKNRIGEKRKADDDDEGEWGQEEEEEQPSKRHKGDGDGLLLEEEMELETGLFGRSGPEKPDHPTNQKEKPSTSRKDVPKVLHDSSKDNITVFVSNLSYNMTDPEVKLKELFESCGEVSQVRPVFSNKGTFRGYCYVEFKDEKSALQALGMDRKVVEGRPMFVSPCVDKNKNPDFKVFRYSTTLEKHKLFISGLPFSCTKEELEDICKAHGNVKDIRLVTNRAGKPKGLAYVEYENEAQASQAVLKMDGLTIKEHVIKVAISNPPLRKLPDKAEAGRASQFAVPRQIYGARGKGRTQLSMMPRALQRQSNPVAKAENGMVQNSPATSSERTEEPKKMSNADFAKMLLNK", "length": 933, "header": "tr|A0A8V0ZI49-1|A0A8V0ZQW6_CHICK Computationally mapped isoform of Spliceosome associated factor 3, U4/U6 recycling protein OS=Gallus gallus OX=9031 GN=SART3 PE=1 SV=1 CANONICAL=A0A8V0ZQW6-1" }, "locus": { "chromosome": "15", "start_pos": 6535898, "end_pos": 6523065, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054649.1", "url": "https://www.ensembl.org/id/ENSGALT00010054649.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033012.1", "url": "https://www.ensembl.org/id/ENSGALP00010033012.1" } ] } }, { "isoform_ac": "A0A8V0ZI54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6/entry#A0A8V0ZI54-1", "sequence": { "sequence": "MRRRRTRRRSSGWRSRLSINAFDYNCHLDLIKLLRQEGELVKLRRARQKMSELFPLTEEIWLDWLKDEIKMASEVSEREKVYELFERAVKDYICPEIWLEYAQYSIGGIGQEGGIEKVRSIFERALTAVGLHVTKGTALWEAYREFENAILETAQPAPGSVPSPEQQQMLCSQLERIHTLFRRQLGIPLLDMEASYAEYEEWSEDPIPETTIKNYKKALQQLEKCKPYEEALLGAETPKLAEYQAYIDFEMKAGDPARIQLIYERALAENCLVPDLWARYNQYLDRQLKVKELVLSAHDRAVRNCPWTVGLWIQYLLAMERHGVDHCIISDMFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFTQDSSKELEELRSAFARAVEYLKQEVEERFSESGDPSCTIMQNWARVEARLCNNMQKARELWDNIMTKGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTLERIEGTLEDWDAAVQKTENRLARVNEQRAKAAEKEAALARQEEEKAEQRKQSRAEKKASKKAKKNRIGEKRKADDDDEGEWGQEEEEEQPSKRHKGDGDGLLLEEEMELETGLFGRSGPEKPDHPTNQKEKPSTSRKDVPKVLHDSSKDNITVFVSNLSYNMTDPEVKLKELFESCGEVSQVRPVFSNKGTFRGYCYVEFKDEKSALQALGMDRKVVEGRPMFVSPCVDKNKNPDFKVFRYSTTLEKHKLFISGLPFSCTKEELEDICKAHGNVKDIRLVTNRAGKPKGLAYVEYENEAQASQAVLKMDGLTIKEHVIKVAISNPPLRKLPDKAEAGRASQFAVPRQIYGARGKGRTQLSMMPRALQRQSNPVAKAENGMVQNSPATSSERTEEPKKMSNADFAKMLLNK", "length": 892, "header": "tr|A0A8V0ZI54-1|A0A8V0ZQW6_CHICK Computationally mapped isoform of Spliceosome associated factor 3, U4/U6 recycling protein OS=Gallus gallus OX=9031 GN=SART3 PE=1 SV=1 CANONICAL=A0A8V0ZQW6-1" }, "locus": { "chromosome": "15", "start_pos": 6535774, "end_pos": 6523065, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054657.1", "url": "https://www.ensembl.org/id/ENSGALT00010054657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033017.1", "url": "https://www.ensembl.org/id/ENSGALP00010033017.1" } ] } }, { "isoform_ac": "A0A8V0ZQW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6/entry#A0A8V0ZQW6-1", "sequence": { "sequence": "MAFAEEGSLGVPQCYVCVRGLSGLGAASSVICRTLKLGLYKRDLIGGAAEVVGACSISLLSINAFDYNCHLDLIKLLRQEGELVKLRRARQKMSELFPLTEEIWLDWLKDEIKMASEVSEREKVYELFERAVKDYICPEIWLEYAQYSIGGIGQEGGIEKVRSIFERALTAVGLHVTKGTALWEAYREFENAILETAQPAPGSVPSPEQQQMLCSQLERIHTLFRRQLGIPLLDMEASYAEYEEWSEDPIPETTIKNYKKALQQLEKCKPYEEALLGAETPKLAEYQAYIDFEMKAGDPARIQLIYERALAENCLVPDLWARYNQYLDRQLKVKELVLSAHDRAVRNCPWTVGLWIQYLLAMERHGVDHCIISDMFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFTQDSSKELEELRSAFARAVEYLKQEVEERFSESGDPSCTIMQNWARVEARLCNNMQKARELWDNIMTKGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTLERIEGTLEDWDAAVQKTENRLARVNEQRAKAAEKEAALARQEEEKAEQRKQSRAEKKASKKAKKNRIGEKRKADDDDEGEWGQEEEEEQPSKRHKGDGDGLLLEEEMELETGLFGRSGPEKPDHPTNQKEKPSTSRKDVPKVLHDSSKDNITVFVSNLSYNMTDPEVKLKELFESCGEVSQVRPVFSNKGTFRGYCYVEFKDEKSALQALGMDRKVVEGRPMFVSPCVDKNKNPDFKVFRYSTTLEKHKLFISGLPFSCTKEELEDICKAHGNVKDIRLVTNRAGKPKGLAYVEYENEAQASQAVLKMDGLTIKEHVIKVAISNPPLRKLPDKAEAGRASQFAVPRQIYGARGKGRTQLSMMPRALQRQSNPVAKAENGMVQNSPATSSERTEEPKKMSNADFAKMLLNK", "length": 935, "header": "tr|A0A8V0ZQW6-1|A0A8V0ZQW6_CHICK Isoform 1 of Spliceosome associated factor 3, U4/U6 recycling protein OS=Gallus gallus OX=9031 GN=SART3 PE=1 SV=1 CANONICAL=A0A8V0ZQW6-1" }, "locus": { "chromosome": "15", "start_pos": 6535517, "end_pos": 6523065, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054645.1", "url": "https://www.ensembl.org/id/ENSGALT00010054645.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033010.1", "url": "https://www.ensembl.org/id/ENSGALP00010033010.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416890", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416890", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B3DJT0-1", "protein_name": "Spliceosome associated factor 3, U4/U6 recycling protein", "gene_name": "sart3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAATGNEEQTLLPDIEEEAEGMEREMESEDDEEEGMGVEHSEEEDEEDTSEDERENEAEIQRLEEQLSINAFDYNCHVDLIKLLRQEGKLHRLRKARQKMSELFPLTEEIWLDWLKDEIRITEDESDREKVYELFERAIKDYVCPEIWLEYVQYSIGGMGAQGGIERVRSIFERALTAVGLHMTKGASIWEAYREFEIVILSTVQPPPGTVPSQEQQELLSAQLERIHTLFRRQLAVPLMDMEGTYAEYSDWADDGVPETVTHQYRRALQQMEKGKPYEEALLVSEPPKLAEYQSYIDFEIKEGDPARVQIIFERALAENCLVPDLWIKYTTYLDRQLKIKDLVLSAHERAVRNCPWTMGLWKSYLLALERHGADHQTVKDVFEKALNAGFIQATDYVEIWQSYLDYLRRRVDFSKEWSRELDELRAAFSRSLEYLKQDVEERFSESGDLSCTLMQIWARIEALHCKNMQKARELWDSIMTKGNAKYANMWLEYYNLERSYGDAAHCRKALHRAVQCTSDYPEHVCDVLLNFERVEGSLEDWDAAVQKTETKLNRVCEQRARVAEKEALHARQEEEKAEQRRKVKADKKAQKKGQKANRTGDKRKAEDDDEEEWGEEAELPSKRLRGEDDFDSTVTEELMETESGLFGRRAPPARKTEPPGFRKNQQGAPEPQRQPHDMPKEQRKDENCVFVSNLTFNMEDPEGKLRTLFQGCGTIQQVRPVFTAKGTFRGYCYVQFEDRLAVPEALKMDRQEVDGRPMYVSPCVDKNKNPDFKVFKYKTSMEKHKIFISGLPYSATKETLEDLCKEHGTIRAIRIVTNRSGKSKGLAYVEFEDEAQASQAVLKMDGTMLENFTLSVAISNPPGRRMKDEAAPSRFLGAAMPRQLQGARGKGRTQISLLPRSLYRQSTPDAKAENGTISAPHATVTDGETSLDTQTKSLSNEDFARMLLKK", "length": 951 }, "evidence": [ { "id": "A0A8V0ZQW6", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZAS8-1", "protein_name": "Spliceosome associated factor 3, U4/U6 recycling protein", "gene_name": "Sart3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATATASSASEPEVEPQARPEAEGEEDEAKPAGVGRKVLSSAETAKAKGPEREVHQEGVSESDGDEEDAAMASSAESSAGEDEWEYDEEEEKNQLEIERLEEQLSINGYDYNCHVGLIRLLRLEGELNKVRMARQKMSEIFPLTEELWLEWLHDEISMAVDGLDRERVYELFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARPIAAFLSPSDREQTFDSQLERVHSLFRRQLAIPLYEMEATFAEYEEWSEEPIPESVLQSYQKALGQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKVGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSVHSRAVRNCPWTVALWSRYLLAMERHGLDHQMISATFENALSAGFIQATDYVEIWQVYLDYLRRRVDFRQDSSKELEELRSMFTRALEYLQQEVEERFSESGDPSCLIMQSWARVEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDLAIQKTETRLARVNEQRMKAAEKEAALVQQEEEKAEQRKKVRAEKKALKKKKTRGADKRKAGEDDDERECGEEEEEQPSKRRRMENSLASGVASAKEEETKLSGKCLTIDVAPPSKQKEKAASLKRDMPKVAHDSSKDSVTVFVSNLPYSIEEPEVKLRPLFEACGEVVQIRPIFSNRGDFRGYCYVEFKEEKSAQQALDLDRKNVEGRPMFVSPCVDKSKNPDFKMFRYSTTLEKHKLFISGLPFSCTKEELEGICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVLKMDGMTIKENVIKVAISNPPQRKVPEKPEVRTAPGAPMVPRQMYGARGKGRTQLSLLPRALQRQGAAPQAENGPAPGLAATTSVATEAPKMSNADFAKLLLRK", "length": 978 }, "evidence": [ { "id": "A0A8V0ZQW6", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15020-1", "protein_name": "Spliceosome associated factor 3, U4/U6 recycling protein", "gene_name": "SART3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATAAETSASEPEAESKAGPKADGEEDEVKAARTRRKVLSRAVAAATYKTMGPAWDQQEEGVSESDGDEYAMASSAESSPGEYEWEYDEEEEKNQLEIERLEEQLSINVYDYNCHVDLIRLLRLEGELTKVRMARQKMSEIFPLTEELWLEWLHDEISMAQDGLDREHVYDLFEKAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLALWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQNYNKALQQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIWQAYLDYLRRRVDFKQDSSKELEELRAAFTRALEYLKQEVEERFNESGDPSCVIMQNWARIEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGSLEDWDIAVQKTETRLARVNEQRMKAAEKEAALVQQEEEKAEQRKRARAEKKALKKKKKIRGPEKRGADEDDEKEWGDDEEEQPSKRRRVENSIPAAGETQNVEVAAGPAGKCAAVDVEPPSKQKEKAASLKRDMPKVLHDSSKDSITVFVSNLPYSMQEPDTKLRPLFEACGEVVQIRPIFSNRGDFRGYCYVEFKEEKSALQALEMDRKSVEGRPMFVSPCVDKSKNPDFKVFRYSTSLEKHKLFISGLPFSCTKEELEEICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKMDGMTIKENIIKVAISNPPQRKVPEKPETRKAPGGPMLLPQTYGARGKGRTQLSLLPRALQRPSAAAPQAENGPAAAPAVAAPAATEAPKMSNADFAKLFLRK", "length": 963 }, "evidence": [ { "id": "A0A8V0ZQW6", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54E37-1", "protein_name": "RRM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDINEDEYNDEEMKAVLKEDSSDSSDDYENNNEDLSNSSDDDDDDDDDGDDSSDDDDDDNMESKTDYENSSEGLEVGLLEIKLREDPYSFEKNLNYINALSKFTKQSNYQTLREAREKFQSIHPLSQDIWLAWFSDEQKYMKTDNDKQYILSLYEKALNDFISVKINVSYCKFIIKINTNSGGLINNVKEIRKQFERSLEQCGDDIIESPLLWSEYRMFEQMLLSQIKDDKEKQTQIKIIRDLYHRQLSNPMIGLHSIYNDYQQWEHSQSIDNNNNNNNNQEKEKEEKEKEEKEIKLKFEKSLKQFKEREPFEIALKEKKYLDQRKWKEYIEFEKQQQHNDKPMRVATLFERQLKSFSNHFSIWSFYLTYLEKFTNFKDLHLKVFSRSLRSIYYSGEHWSKYLLLLEERVHNDNDNDKRVKIEQEFQRSLVSGLKSEYDYQLVYNTYIDYNWRSIIKKLNTDSNANSNGNGNNNNNNNNNNNNNNNNNNNNNNNNNNNNSISENDKQLMKSLFETMNNQMSTIDVNNYTTVDRYMYIAQFEWRQFNDLSRYREIVDYVLSIDPSQYWIWCQYISFEMEQKQFQSVRELFKKASSHIRFDDPSSRIWQDWFTFERGYGDINQYRAVSDRYSIIQNKYNKEQERYLQQQQQQQQKQQQQNKRKEKDDGKNKDEKRISKKQKNENHKEKGDQDEFKKPLPPTSKKEKEKEKDLPKKLIILNLSFDTAEPDLHKIFDKYGQIKSLKLVLDKNGKSKGICFILYKSHESANKALEMDQQIIKNRTICVQYSKDQQINDHVESNQTLTTTATTTTTTNEIDFENHIGLTVFINNLSPSVNKEKLEQFLRHNGVTGIKDIRVVLKARPFAYIDLIDKENLKKALSLDKKYFLSKLINVNLSKPPSSISPANNNNDNNNNNNNNTITSNGNDTEFIKEIPSRKPTLLVPRGIKNKK", "length": 949 }, "evidence": [ { "id": "A0A8V0ZQW6", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9JLI8-1", "protein_name": "Spliceosome associated factor 3, U4/U6 recycling protein", "gene_name": "Sart3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTAASSASEPEVEPQAGPEAEGEEDEAKPAGVQRKVLSGAVAAEAAEAKGPGWDLQREGASGSDGDEEDAMASSAESSAGEDEWEYDEEEEKNQLEIERLEEQLSINGYDYNCHVELIRLLRLEGELSRVRAARQKMSELFPLTEELWLEWLHDEISMAMDGLDREHVYELFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYEMEATFAEYEEWSEEPMPESVLQSYQKALGQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSVHSRAVRNCPWTVALWSRYLLAMERHGLDHQTISATFENALSAGFIQATDYVEIWQVYLDYLRRRVDFRQDSSKELEELRSMFTRALEYLQQEVEERFSESGDPSCLIMQSWARVEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDLAIQKTETRLARVNEQRMKAAEKEAALVQQEEEKAEQRKKVRAEKKALKKKKKTRGADKRREDEDEENEWGEEEEEQPSKRRRTENSLASGEASAMKEETELSGKCLTIDVGPPSKQKEKAASLKRDMPKVAHDSSKDSVTVFVSNLPYSIEEPEVKLRPLFEVCGEVVQIRPIFSNRGDFRGYCYVEFGEEKSAQQALELDRKIVEGRPMFVSPCVDKSKNPDFKVFRYSTTLEKHKLFISGLPFSCTKEELEDICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKMDGMTIRENVIKVAISNPPQRKVPEKPEVRTAPGAPMLPRQMYGARGKGRTQLSLLPRALQRQGAAPQAENGPAPGPAVAPSVATEAPKMSNADFAKLLLRK", "length": 962 }, "evidence": [ { "id": "A0A8V0ZQW6", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "U6atac snRNA binding", "id": "GO:0030624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030624", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "U4 snRNA binding", "id": "GO:0030621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030621", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "ubiquitin-specific protease binding", "id": "GO:1990381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990381", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "U6 snRNA binding", "id": "GO:0017070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017070", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "ASAP 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"name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "regulation of RNA metabolic process", "id": "GO:0051252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "spliceosomal tri-snRNP complex assembly", "id": "GO:0000244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000244", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" }, { "name": "transcription elongation-coupled chromatin remodeling", "id": "GO:0140673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140673", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 675, "end_pos": 677, "annotation": "n_glycosylation_sequon" }, { "start_pos": 682, "end_pos": 684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 686, "end_pos": 688, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8V0ZNJ9", "uniprot_id": "A0A8V0ZNJ9_CHICK", "mass": { "chemical_mass": 45873.0, "monoisotopic_mass": 45873.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF385A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ] } ], "protein_names": [ { "name": "Zinc finger protein 385A", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF385A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9", "locus": { "chromosome": "34", "start_pos": 749817, "end_pos": 745032, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022473", "url": "https://www.ensembl.org/id/ENSGALG00010022473" } ] } } ], "crossref": [ { "id": "A0A8V0ZNJ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZI70", "url": "https://www.orthodb.org/?gene=A0A8V0ZI70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNJ9", "url": "https://www.orthodb.org/?gene=A0A8V0ZNJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23067:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23067:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZI70", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPVPKAVLGAALTKPRRPVIACSICQIRFNSESQAAAHYQGNRHARRLKGLEAARARRGGDSGDSQDPPAPTPNPTGETPERKGGSLRPEVSPAVLSSPQRPQLPGERGGGPGGAAEGEEEEEKAKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTLVEARSGLGPIRAFPRLGGGTGTPPDEAPERSFHCQICNVHLNSELQLKQHISSRRHRDGVAGKPNPLLSRHKKSWGTCEGVWGTLTPSLTPQAPLPFPKELPKALAGGGLLPPPLALAAAAAAMAAPPAGTAPPRTPPPARPPPGARPAASPPRDPSVLPTPPSSSPHTDPPLTPPPPLGNRCPATSQQLVPSCPSPPPPPPPWLLPGKPLPGNRPAMVRAVILRHNPATATVAWQPDVAITPEWLPGNGYPAKEPSNLPGNGYLATRPASCLETSPATVT", "length": 440, "header": "tr|A0A8V0ZNJ9-1|A0A8V0ZNJ9_CHICK Isoform 1 of Zinc finger protein 385A OS=Gallus gallus OX=9031 GN=ZNF385A PE=4 SV=1 CANONICAL=A0A8V0ZNJ9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZI70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9/entry#A0A8V0ZI70-1", "sequence": { "sequence": "MLRAPCPLGPPHGRLLLPDAAAAALRLLPPLPGMEPVPKAVLGAALTKPRRPVIACSICQIRFNSEESSPQRPQLPAPPGPPPPLIPRLWPQRHQGERGGGPGGAAEGEEEEEKAKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTLVEARSGLGPIRAFPRLGGGTGTPPDEAPERSFHCQICNVHLNSELQLKQHISSRRHRDGVAGKPNPLLSRHKKPRSPRSW", "length": 228, "header": "tr|A0A8V0ZI70-1|A0A8V0ZNJ9_CHICK Computationally mapped isoform of Zinc finger protein 385A OS=Gallus gallus OX=9031 GN=ZNF385A PE=4 SV=1 CANONICAL=A0A8V0ZNJ9-1" }, "locus": { "chromosome": "34", "start_pos": 748759, "end_pos": 745048, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054674.1", "url": "https://www.ensembl.org/id/ENSGALT00010054674.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033032.1", "url": "https://www.ensembl.org/id/ENSGALP00010033032.1" } ] } }, { "isoform_ac": "A0A8V0ZNJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9/entry#A0A8V0ZNJ9-1", "sequence": { "sequence": "MEPVPKAVLGAALTKPRRPVIACSICQIRFNSESQAAAHYQGNRHARRLKGLEAARARRGGDSGDSQDPPAPTPNPTGETPERKGGSLRPEVSPAVLSSPQRPQLPGERGGGPGGAAEGEEEEEKAKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTLVEARSGLGPIRAFPRLGGGTGTPPDEAPERSFHCQICNVHLNSELQLKQHISSRRHRDGVAGKPNPLLSRHKKSWGTCEGVWGTLTPSLTPQAPLPFPKELPKALAGGGLLPPPLALAAAAAAMAAPPAGTAPPRTPPPARPPPGARPAASPPRDPSVLPTPPSSSPHTDPPLTPPPPLGNRCPATSQQLVPSCPSPPPPPPPWLLPGKPLPGNRPAMVRAVILRHNPATATVAWQPDVAITPEWLPGNGYPAKEPSNLPGNGYLATRPASCLETSPATVT", "length": 440, "header": "tr|A0A8V0ZNJ9-1|A0A8V0ZNJ9_CHICK Isoform 1 of Zinc finger protein 385A OS=Gallus gallus OX=9031 GN=ZNF385A PE=4 SV=1 CANONICAL=A0A8V0ZNJ9-1" }, "locus": { "chromosome": "34", "start_pos": 749814, "end_pos": 746438, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054670.1", "url": "https://www.ensembl.org/id/ENSGALT00010054670.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033029.1", "url": "https://www.ensembl.org/id/ENSGALP00010033029.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 320, "start_aa": "Thr", "end_pos": 320, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr320", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" }, { "name": "p53 binding", "id": "GO:0002039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of cytoplasmic translation", "id": "GO:2000765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" }, { "name": "mRNA localization resulting in post-transcriptional regulation of gene expression", "id": "GO:0010609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" }, { "name": "positive regulation of DNA damage response, signal transduction by p53 class mediator", "id": "GO:0043517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043517", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" }, { "name": "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator", "id": "GO:1902166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ9" }, { "id": "PS00028", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 45, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 73, 320 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZP94-1", "uniprot_ac": "A0A8V0ZP94", "uniprot_id": "A0A8V0ZP94_CHICK", "mass": { "chemical_mass": 73142.0, "monoisotopic_mass": 73142.0 }, "refseq": { "ac": "XP_040502648", "name": "cilia- and flagella-associated protein 100 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502648" }, "gene_names": [ { "name": "CFAP100", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP94" } ] }, { "name": "CFAP100", "type": "synonym", "evidence": [ { "id": "XP_040502648", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502648" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 100", "type": "synonym", "evidence": [ { "id": "A0A8V0ZP94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP94/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 100 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_040502648", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502648" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040502648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502648" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP94" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP100", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP94", "locus": { "chromosome": "12", "start_pos": 10850048, "end_pos": 10837959, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021183", "url": "https://www.ensembl.org/id/ENSGALG00010021183" } ] } } ], "crossref": [ { "id": "A0A8V0ZP94", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP94", "database": "AlphaFoldDB", "categories": [] }, { "id": "427589", "url": "https://www.ncbi.nlm.nih.gov/gene/427589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIA4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP94", "url": "https://www.orthodb.org/?gene=A0A8V0ZP94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21683", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21683", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21683:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21683:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13863", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13863", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040502648", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040502648", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVLSSNHSALSQETHSAYSAGTTSESVMPSVYEESVCESLSSKPGMETYLVSELSEEDEEPIYKNPFTIPPDIDIFAIRNKERKKAKAERERMKTMKIHEKMTYSVKNKAKERGLRKALKKEEEEENRKQETDEERLKALQECLSWKIAIKKDYPLEKETFRDYINDRREIFLLEYAIAVKREEIQKLEKIAKKEERKLEKAEYNLEKDIAIFDEFLKENHKSSVQALKIAEKESAAKAKKIVQIHAIGSQIMSLQSDITRFENSLREYKMYRDFLYQLSPKEWQEEYEKKHGKQLKTADKESASEKSKCRGRAAHSSGGQPHAPSVHLLLCPGLTIEMNTNAIDVPSSLLSVESVNSSLSPGTRPQLKSLLKPLSTENLNSSEDQESEICSDEDEEPELYFTDPQQLLSVFAEMEEQNFSYLCNFQETQKEINELQHTFINAQQRKDRERAQLKEVSLTLKSTVTKLEERAADLKLRVEDFSSEHKVDVQDKMLASLGRKVREVYGHCIGESREGMETMEMLAAIEKKLIELLDNLERIPPAKIAEIEKAKKRERRKRLREEKEQQQKQMQEERLQRALERAQANIEKKTGRRLMFRSSPPARKEKKEQSQEQRDKEKEEMLYYFT", "length": 628, "header": "tr|A0A8V0ZP94-1|A0A8V0ZP94_CHICK Isoform 1 of Cilia and flagella associated protein 100 OS=Gallus gallus OX=9031 GN=CFAP100 PE=4 SV=1 CANONICAL=A0A8V0ZP94-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP94/entry#A0A8V0ZIA4-1", "sequence": { "sequence": "MSVLSSNHSALSQETHSAYSAGTTSESVMPSVYEESVCESLSSKPGMETYLVSELSEEDEEPIYKNPFTIPPDIDIFAIRNKERKKAKAERERMKTMKIHEKMTYSVKNKAKERGLRKALKKEEEEENRKQETDEERLKALQECLSWKIAIKKDYPLEKETFRDYINDRREIFLLEYAIAVKREEIQKLEKIAKKEERKLEKAEYNLEKDIAIFDEFLKENHKSSVQALKIAEKESAAKAKKIVQIHAIGSQIMSLQSDITRFENSLREYKMYRDFLYQLSPKEWQEEYEKKHGKQLKTADKESASEKSLTIEMNTNAIDVPSSLLSVESVNSSLSPGTRPQLKSLLKPLSTENLNSSEDQESEICSDEDEEPELYFTDPQQLLSVFAEMEEQNFSYLCNFQETQKEINELQHTFINAQQRKDRERAQLKEVSLTLKSTVTKLEERAADLKLRVEDFSSEHKVDVQDKMLASLGRKVREVYGHCIGESREGMETMEMLAAIEKKLIELLDNLERIPPAKIAEIEKAKKRERRKRLREEKEQQQKQMQEERLQRALERAQANIEKKTGRRLMFRSSPPARKEKKEQSQEQRDKEKEEMLYYFT", "length": 602, "header": "tr|A0A8V0ZIA4-1|A0A8V0ZP94_CHICK Computationally mapped isoform of Cilia and flagella associated protein 100 OS=Gallus gallus OX=9031 GN=CFAP100 PE=4 SV=1 CANONICAL=A0A8V0ZP94-1" }, "locus": { "chromosome": "12", "start_pos": 10849837, "end_pos": 10839722, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051334.1", "url": "https://www.ensembl.org/id/ENSGALT00010051334.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030525.1", "url": "https://www.ensembl.org/id/ENSGALP00010030525.1" } ] } }, { "isoform_ac": "A0A8V0ZP94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP94/entry#A0A8V0ZP94-1", "sequence": { "sequence": "MSVLSSNHSALSQETHSAYSAGTTSESVMPSVYEESVCESLSSKPGMETYLVSELSEEDEEPIYKNPFTIPPDIDIFAIRNKERKKAKAERERMKTMKIHEKMTYSVKNKAKERGLRKALKKEEEEENRKQETDEERLKALQECLSWKIAIKKDYPLEKETFRDYINDRREIFLLEYAIAVKREEIQKLEKIAKKEERKLEKAEYNLEKDIAIFDEFLKENHKSSVQALKIAEKESAAKAKKIVQIHAIGSQIMSLQSDITRFENSLREYKMYRDFLYQLSPKEWQEEYEKKHGKQLKTADKESASEKSKCRGRAAHSSGGQPHAPSVHLLLCPGLTIEMNTNAIDVPSSLLSVESVNSSLSPGTRPQLKSLLKPLSTENLNSSEDQESEICSDEDEEPELYFTDPQQLLSVFAEMEEQNFSYLCNFQETQKEINELQHTFINAQQRKDRERAQLKEVSLTLKSTVTKLEERAADLKLRVEDFSSEHKVDVQDKMLASLGRKVREVYGHCIGESREGMETMEMLAAIEKKLIELLDNLERIPPAKIAEIEKAKKRERRKRLREEKEQQQKQMQEERLQRALERAQANIEKKTGRRLMFRSSPPARKEKKEQSQEQRDKEKEEMLYYFT", "length": 628, "header": "tr|A0A8V0ZP94-1|A0A8V0ZP94_CHICK Isoform 1 of Cilia and flagella associated protein 100 OS=Gallus gallus OX=9031 GN=CFAP100 PE=4 SV=1 CANONICAL=A0A8V0ZP94-1" }, "locus": { "chromosome": "12", "start_pos": 10849837, "end_pos": 10839722, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051332.1", "url": "https://www.ensembl.org/id/ENSGALT00010051332.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030523.1", "url": "https://www.ensembl.org/id/ENSGALP00010030523.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP94" } ], "pmid": "" }, { "name": "ciliary 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZIC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDPGGMRGAAETVAALGEFGGRGHLLAPPIAPPPPGPAEVEVTWQEILSLSELQGLDVAADPSYDPQFCPLPPPAPLYPLQPLPPPIPPTPPFPPHFLPPFPTPPCPPPAPHYPPPPPPSTLPAPPPRSSRDARRALALSLPIGPDAIINLPAEDFNALLGRSHLSGAELALARDIRRRGKNKVAAQKCRRRKLEAIAGLQEELGRLGRERERLLRARGQAERALGALRRDLAHITAQVLGTLRDGGGDQPHIQGAANEGPGGKVEGGAGFGEGGSEEGGADVLQCVEPSGALK", "length": 295, "header": "tr|A0A8V0ZQH1-1|A0A8V0ZQH1_CHICK Isoform 1 of Nuclear factor, erythroid 2 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZQH1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH1/entry#A0A8V0ZIC3-1", "sequence": { "sequence": "MGDPGGMRGAAETVAALGEFGGRGHLLAPPIAPPPPGPAEVEVTWQEILSLSELQGLDVAADPSYDPQFCPLPPPAPLYPLQPLPPPIPPTPPFPPHFLPPFPTPPCPPPAPHYPPPPPPSTLPAPPPRSSRDARRALALSLPIGPDAIINLPAEDFNALLGRSHLSGAELALARDIRRRGKNKVAAQKCRRRKLEAIAGLQEELGRLGRERERLLRARGQAERALGALRRDLAHITAQSAIDRQHGRANKTEAPGSPRLKECFHGTEN", "length": 269, "header": "tr|A0A8V0ZIC3-1|A0A8V0ZQH1_CHICK Computationally mapped isoform of Nuclear factor, erythroid 2 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZQH1-1" }, "locus": { "chromosome": "34", "start_pos": 762672, "end_pos": 758867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054736.1", "url": "https://www.ensembl.org/id/ENSGALT00010054736.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033078.1", "url": "https://www.ensembl.org/id/ENSGALP00010033078.1" } ] } }, { "isoform_ac": "A0A8V0ZQH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH1/entry#A0A8V0ZQH1-1", "sequence": { "sequence": "MGDPGGMRGAAETVAALGEFGGRGHLLAPPIAPPPPGPAEVEVTWQEILSLSELQGLDVAADPSYDPQFCPLPPPAPLYPLQPLPPPIPPTPPFPPHFLPPFPTPPCPPPAPHYPPPPPPSTLPAPPPRSSRDARRALALSLPIGPDAIINLPAEDFNALLGRSHLSGAELALARDIRRRGKNKVAAQKCRRRKLEAIAGLQEELGRLGRERERLLRARGQAERALGALRRDLAHITAQVLGTLRDGGGDQPHIQGAANEGPGGKVEGGAGFGEGGSEEGGADVLQCVEPSGALK", "length": 295, "header": "tr|A0A8V0ZQH1-1|A0A8V0ZQH1_CHICK Isoform 1 of Nuclear factor, erythroid 2 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZQH1-1" }, "locus": { "chromosome": "34", "start_pos": 760519, "end_pos": 758867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054735.1", "url": "https://www.ensembl.org/id/ENSGALT00010054735.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033077.1", "url": "https://www.ensembl.org/id/ENSGALP00010033077.1" } ] } }, { "isoform_ac": "A0A8V0ZW53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH1/entry#A0A8V0ZW53-1", "sequence": { "sequence": "MGDPGGMRGAAETVAALGEFGGRGHLLAPPIAPPPPGPAEVEVTWQEILSLSELQGLDVAADPSYDPQFCPLPPPAPLYPLQPLPPPIPPTPPFPPHFLPPFPTPPCPPPAPHYPPPPPPSTLPAPPPRSSRDARRALALSLPIGPDAIINLPAEDFNALLGRSHLSGAELALARDIRRRGKNKVAAQKCRRRKLEAIAGLQEELGRLGRERERLLRARGQAERALGALRRDLAHITAQSRGRQR", "length": 245, "header": "tr|A0A8V0ZW53-1|A0A8V0ZQH1_CHICK Computationally mapped isoform of Nuclear factor, erythroid 2 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZQH1-1" }, "locus": { "chromosome": "34", "start_pos": 766070, "end_pos": 758867, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054737.1", "url": "https://www.ensembl.org/id/ENSGALT00010054737.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033079.1", "url": "https://www.ensembl.org/id/ENSGALP00010033079.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 104, "start_aa": "Thr", "end_pos": 104, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr104", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 91, "start_aa": "Thr", "end_pos": 91, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr91", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPF9-1", "uniprot_ac": "A0A8V0ZPF9", "uniprot_id": "A0A8V0ZPF9_CHICK", "mass": { "chemical_mass": 85394.0, "monoisotopic_mass": 85394.0 }, "refseq": {}, "gene_names": [ { "name": "FBXL18", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9" } ] } ], "protein_names": [ { "name": "F-box and leucine rich repeat protein 18", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXL18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9", "locus": { "chromosome": "14", "start_pos": 4153605, "end_pos": 4177826, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021214", "url": "https://www.ensembl.org/id/ENSGALG00010021214" } ] } } ], "crossref": [ { "id": "A0A8V0ZPF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22128", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22128", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIH1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZII0", "url": "https://www.orthodb.org/?gene=A0A8V0ZII0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPF4", "url": "https://www.orthodb.org/?gene=A0A8V0ZPF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPF9", "url": "https://www.orthodb.org/?gene=A0A8V0ZPF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16134:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16134:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZIH1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZII0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZII0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZII0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZII0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLSGRPLTSASRGHAQDGGGGSVASRGSRVMAAPEEPCGGAERGREAAGLSRARRDPAAAAMSRCAEDLASGENEEGSNGINLMEFSDEILLHILSYVPCTDLVLNVRKTCRKLATLCLDKSLTHTVLLQKDYKVNKDKVKQLMRDIGKEIYQLNMAGCYWLPSSTTDHVTRCKNLVKLNLSGCRITSLRLSKMLSTLQHLRSLAIDVNPGFDASQLSSECKATLSRVSELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRSREGFMLSGQLMVGESNVPHYQNLRVFYARLAPGYVNQEVVRLYLAVLSDRTPENLHAFLISAPGSFAETGATKNLLDSMARNVRLDALQLPKAWLNGSGLLQHLKFNNPFYFSFSRCTLSGGHLIQRVINGGKDLKSLTSLNLSGCVHCLAPESLFRRAEDDIDSSILESLVVSCCNLRHLNLSAAHHHSSESIGNHLCQLLSRLKHLLSLALPVCSITDVAVSMEKPPTQPNAVPQTFGKKTRVGVQTYPRTLTDQACQKLESSVFWMLMRSLRCLETLEIIGSSFSSAMPRNEPAIRNSLPPCVRAQSVGDSEVAAISQLTYLQSLTLAQLPNIVTGSGLVSIGLQCQHLRTLSLANLGMMGKMVYMSALMDMLKHCKCLRDLRLEQPYFSAGSQFFQALSHCSSLQRLCIVSRSGTLQSDAVMSFMANCLEVIMCHMFMGESLTVCRNLQQSIVRSFQADRPALNVVIFPLLHEDLTEVIRDVPMRHLDEITLFKSRVAEEPPNLWW", "length": 774, "header": "tr|A0A8V0ZPF9-1|A0A8V0ZPF9_CHICK Isoform 1 of F-box and leucine rich repeat protein 18 OS=Gallus gallus OX=9031 GN=FBXL18 PE=4 SV=1 CANONICAL=A0A8V0ZPF9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9/entry#A0A8V0ZIH1-1", "sequence": { "sequence": "MEFSDEILLHILSYVPCTDLVLNVRKTCRKLATLCLDKSLTHTVLLQKDYKVNKDKVKQLMRDIGKEIYQLNMAGCYWLPSSTTDHVTRCKNLVKLNLSGCRITSLRLSKMLSTLQHLRSLAIDVNPGFDASQLSSECKATLSRVSELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRSREGFMLSGQLMVGESNVPHYQNLRVFYARLAPGYVNQEVVRLYLAVLSDRTPENLHAFLISAPGSFAETGATKNLLDSMARNVRLDALQLPKAWLNGSGLLQHLKFNNPFYFSFSRCTLSGGHLIQRVINGGKDLKSLTSLNLSGCVHCLAPESLFRRAEDDIDSSILESLVVSCCNLRHLNLSAAHHHSSESIGNHLCQLLSRLKHLLSLALPVCSITDVAVSMEKPPTQPNAVPQTFGKKTRVGVQTYPRTLTDQACQKLESSVFWMLMRSLRCLETLEIIGSSFSSAMPRNEPAIRNSLPPCVRAQSVGDSEVAAISQLTYLQSLTLAQLPNIVTGSGLVSIGLQCQHLRTLSLANLGMMGKMVYMSALMDMLKHCKCLRDLRLEQPYFSAGSQFFQALSHCSSLQRLCIVSRSGTLQSDAVMSFMANCLEVIMCHMFMGESLTVCRNLQQSIVRRASAPTASSAPEVL", "length": 651, "header": "tr|A0A8V0ZIH1-1|A0A8V0ZPF9_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 18 OS=Gallus gallus OX=9031 GN=FBXL18 PE=4 SV=1 CANONICAL=A0A8V0ZPF9-1" }, "locus": { "chromosome": "14", "start_pos": 4175456, "end_pos": 4168259, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051403.1", "url": "https://www.ensembl.org/id/ENSGALT00010051403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030594.1", "url": "https://www.ensembl.org/id/ENSGALP00010030594.1" } ] } }, { "isoform_ac": "A0A8V0ZII0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9/entry#A0A8V0ZII0-1", "sequence": { "sequence": "MILFTFALETQGFSTLGSAFPADCKYTDLASGENEEGSNGINLMEFSDEILLHILSYVPCTDLVLNVRKTCRKLATLCLDKSLTHTVLLQKDYKVNKDKVKQLMRDIGKEIYQLNMAGCYWLPSSTTDHVTRCKNLVKLNLSGCRITSLRLSKMLSTLQHLRSLAIDVNPGFDASQLSSECKATLSRVSELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRSREGFMLSGQLMVGESNVPHYQNLRVFYARLAPGYVNQEVVRLYLAVLSDRTPENLHAFLISAPGSFAETGATKNLLDSMARNVRLDALQLPKAWLNGSGLLQHLKFNNPFYFSFSRCTLSGGHLIQRVINGGKDLKSLTSLNLSGCVHCLAPESLFRRAEDDIDSSILESLVVSCCNLRHLNLSAAHHHSSESIGNHLCQLLSRLKHLLSLALPVCSITDVAVSMEKPPTQPNAVPQTFGKKTRVGVQTYPRTLTDQACQKLESSVFWMLMRSLRCLETLEIIGSSFSSAMPRNEPAIRNSLPPCVRAQSVGDSEVAAISQLTYLQSLTLAQLPNIVTGSGLVSIGLQCQHLRTLSLANLGMMGKMVYMSALMDMLKHCKCLRDLRLEQPYFSAGSQFFQALSHCSSLQRLCIVSRSGTLQSDAVMSFMANCLEVIMCHMFMGESLTVCRNLQQSIVRSFQADRPALNVVIFPLLHEDLTEVIRDVPMRHLDEITLFKSRVAEEPPNLWW", "length": 732, "header": "tr|A0A8V0ZII0-1|A0A8V0ZPF9_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 18 OS=Gallus gallus OX=9031 GN=FBXL18 PE=4 SV=1 CANONICAL=A0A8V0ZPF9-1" }, "locus": { "chromosome": "14", "start_pos": 4177340, "end_pos": 4158306, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051409.1", "url": "https://www.ensembl.org/id/ENSGALT00010051409.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030600.1", "url": "https://www.ensembl.org/id/ENSGALP00010030600.1" } ] } }, { "isoform_ac": "A0A8V0ZPF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9/entry#A0A8V0ZPF4-1", "sequence": { "sequence": "MSRCAEDLASGENEEGSNGINLMEFSDEILLHILSYVPCTDLVLNVRKTCRKLATLCLDKSLTHTVLLQKDYKVNKDKVKQLMRDIGKEIYQLNMAGCYWLPSSTTDHVTRCKNLVKLNLSGCRITSLRLSKMLSTLQHLRSLAIDVNPGFDASQLSSECKATLSRVSELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRSREGFMLSGQLMVGESNVPHYQNLRVFYARLAPGYVNQEVVRLYLAVLSDRTPENLHAFLISAPGSFAETGATKNLLDSMARNVRLDALQLPKAWLNGSGLLQHLKFNNPFYFSFSRCTLSGGHLIQRVINGGKDLKSLTSLNLSGCVHCLAPESLFRRAEDDIDSSILESLVVSCCNLRHLNLSAAHHHSSESIGNHLCQLLSRLKHLLSLALPVCSITDVAVSMEKPPTQPNAVPQTFGKKTRVGVQTYPRTLTDQACQKLESSVFWMLMRSLRCLETLEIIGSSFSSAMPRNEPAIRNSLPPCVRAQSVGDSEVAAISQLTYLQSLTLAQLPNIVTGSGLVSIGLQCQHLRTLSLANLGMMGKMVYMSALMDMLKHCKCLRDLRLEQPYFSAGSQFFQALSHCSSLQRLCIVSRSGTLQSDAVMSFMANCLEVIMCHMFMGESLTVCRNLQQSIVRRCGSTEGFSSWKRTNVGRAPWFRLLGCAGSQYLCRLK", "length": 696, "header": "tr|A0A8V0ZPF4-1|A0A8V0ZPF4_CHICK Computationally mapped isoform of F-box and leucine rich repeat protein 18 OS=Gallus gallus OX=9031 GN=FBXL18 PE=4 SV=1 CANONICAL=A0A8V0ZPF9-1" }, "locus": { "chromosome": "14", "start_pos": 4176412, "end_pos": 4167295, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051406.1", "url": "https://www.ensembl.org/id/ENSGALT00010051406.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030597.1", "url": "https://www.ensembl.org/id/ENSGALP00010030597.1" } ] } }, { "isoform_ac": "A0A8V0ZPF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9/entry#A0A8V0ZPF9-1", "sequence": { "sequence": "MASLSGRPLTSASRGHAQDGGGGSVASRGSRVMAAPEEPCGGAERGREAAGLSRARRDPAAAAMSRCAEDLASGENEEGSNGINLMEFSDEILLHILSYVPCTDLVLNVRKTCRKLATLCLDKSLTHTVLLQKDYKVNKDKVKQLMRDIGKEIYQLNMAGCYWLPSSTTDHVTRCKNLVKLNLSGCRITSLRLSKMLSTLQHLRSLAIDVNPGFDASQLSSECKATLSRVSELKQTLYTPSYGVVPCCTSLEKLLLYFEILDRSREGFMLSGQLMVGESNVPHYQNLRVFYARLAPGYVNQEVVRLYLAVLSDRTPENLHAFLISAPGSFAETGATKNLLDSMARNVRLDALQLPKAWLNGSGLLQHLKFNNPFYFSFSRCTLSGGHLIQRVINGGKDLKSLTSLNLSGCVHCLAPESLFRRAEDDIDSSILESLVVSCCNLRHLNLSAAHHHSSESIGNHLCQLLSRLKHLLSLALPVCSITDVAVSMEKPPTQPNAVPQTFGKKTRVGVQTYPRTLTDQACQKLESSVFWMLMRSLRCLETLEIIGSSFSSAMPRNEPAIRNSLPPCVRAQSVGDSEVAAISQLTYLQSLTLAQLPNIVTGSGLVSIGLQCQHLRTLSLANLGMMGKMVYMSALMDMLKHCKCLRDLRLEQPYFSAGSQFFQALSHCSSLQRLCIVSRSGTLQSDAVMSFMANCLEVIMCHMFMGESLTVCRNLQQSIVRSFQADRPALNVVIFPLLHEDLTEVIRDVPMRHLDEITLFKSRVAEEPPNLWW", "length": 774, "header": "tr|A0A8V0ZPF9-1|A0A8V0ZPF9_CHICK Isoform 1 of F-box and leucine rich repeat protein 18 OS=Gallus gallus OX=9031 GN=FBXL18 PE=4 SV=1 CANONICAL=A0A8V0ZPF9-1" }, "locus": { "chromosome": "14", "start_pos": 4176601, "end_pos": 4158306, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051411.1", "url": "https://www.ensembl.org/id/ENSGALT00010051411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030602.1", "url": "https://www.ensembl.org/id/ENSGALP00010030602.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF9" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 129, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 182, "end_pos": 184 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 446, "end_pos": 448 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRC6-1", "uniprot_ac": "A0A8V0ZRC6", "uniprot_id": "A0A8V0ZRC6_CHICK", "mass": { "chemical_mass": 42628.0, "monoisotopic_mass": 42628.0 }, "refseq": { "ac": "XP_015155840", "name": "heterogeneous nuclear ribonucleoprotein A1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155840" }, "gene_names": [ { "name": "HNRNPA1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6" } ] }, { "name": "HNRNPA1", "type": "synonym", "evidence": [ { "id": "XP_015155840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155840" } ] }, { "name": "HNRNPA3", "type": "synonym", "evidence": [ { "id": "XP_015155840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155840" } ] } ], "protein_names": [ { "name": "Heteroous nuclear ribonucleoprotein A1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6/entry#names_and_taxonomy" } ] }, { "name": "heterogeneous nuclear ribonucleoprotein A1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015155840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155840" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015155840", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155840" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HNRNPA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6", "locus": { "chromosome": "34", "start_pos": 761809, "end_pos": 768238, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022517", "url": "https://www.ensembl.org/id/ENSGALG00010022517" } ] } } ], "crossref": [ { "id": "A0A8V0ZRC6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12582", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12582", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12761", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12761", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424136", "url": "https://www.ncbi.nlm.nih.gov/gene/424136", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AQFTKHF", "url": "https://omabrowser.org/oma/group/AQFTKHF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIH7", "url": "https://www.orthodb.org/?gene=A0A8V0ZIH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQM4", "url": "https://www.orthodb.org/?gene=A0A8V0ZQM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRC6", "url": "https://www.orthodb.org/?gene=A0A8V0ZRC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48026:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48026:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9770562", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015155840", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015155840", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIH7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYSSVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFGQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASASQRGRSGSGNFGGGRGGGFGGNDNFSRGGNFGGRGGFGGSRGGGYGGGGDGYNGFGNDGYGGSGPGYSGGNRGYGGSSTYDGYNNGGGGFGGGSGGRRPARGPALAVRNGLSEAGTGSNFGGGGGGNYNDFGSYNNQSSNFGPMKGGNFGGRSSGPYGGGESPRGLRAPRGGCTPTPLSLEHFRPPRRLRQLERRRQLRRREEVLTPAGNKA", "length": 403, "header": "tr|A0A8V0ZRC6-1|A0A8V0ZRC6_CHICK Isoform 1 of Heteroous nuclear ribonucleoprotein A1 OS=Gallus gallus OX=9031 GN=HNRNPA1 PE=1 SV=1 CANONICAL=A0A8V0ZRC6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6/entry#A0A8V0ZIH7-1", "sequence": { "sequence": "MAKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYSSVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFGQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASASQRGGFGGSRGGGYGGGGDGYNGFGNDGYGGSGPGYSGGNRGYGGSSTYDGYNNGGGGFGGGSGGRRPARGPALAVRNGLSEAGTGSNFGGGGGGNYNDFGSYNNQSSNFGPMKGGNFGGRSSGPYGGGGYGSSSGGGSYGGGRRF", "length": 337, "header": "tr|A0A8V0ZIH7-1|A0A8V0ZRC6_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein A1 OS=Gallus gallus OX=9031 GN=HNRNPA1 PE=1 SV=1 CANONICAL=A0A8V0ZRC6-1" }, "locus": { "chromosome": "34", "start_pos": 768153, "end_pos": 763016, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054826.1", "url": "https://www.ensembl.org/id/ENSGALT00010054826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033138.1", "url": "https://www.ensembl.org/id/ENSGALP00010033138.1" } ] } }, { "isoform_ac": "A0A8V0ZQM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6/entry#A0A8V0ZQM4-1", "sequence": { "sequence": "MAKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYSSVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFGQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASASQRGRSGSGNFGGGRGGGFGGNDNFSRGGNFGGRGYGGSGPGYSGGNRGYGGSSTYDGYNNGGGGFGGGSGGRRPARGPALAVRNGLSEAGTGSNFGGGGGGNYNDFGSYNNQSSNFGPMKGGNFGGRSSGPYGGGESPRGLRAPRGGCTPTPLSLEHFRPPRRLRQLERRRQLRRREEVLTPAGNKA", "length": 379, "header": "tr|A0A8V0ZQM4-1|A0A8V0ZQM4_CHICK Computationally mapped isoform of Heteroous nuclear ribonucleoprotein A1 OS=Gallus gallus OX=9031 GN=HNRNPA1 PE=1 SV=1 CANONICAL=A0A8V0ZRC6-1" }, "locus": { "chromosome": "34", "start_pos": 768153, "end_pos": 762855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054816.1", "url": "https://www.ensembl.org/id/ENSGALT00010054816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033132.1", "url": "https://www.ensembl.org/id/ENSGALP00010033132.1" } ] } }, { "isoform_ac": "A0A8V0ZRC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6/entry#A0A8V0ZRC6-1", "sequence": { "sequence": "MAKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYSSVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFGQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASASQRGRSGSGNFGGGRGGGFGGNDNFSRGGNFGGRGGFGGSRGGGYGGGGDGYNGFGNDGYGGSGPGYSGGNRGYGGSSTYDGYNNGGGGFGGGSGGRRPARGPALAVRNGLSEAGTGSNFGGGGGGNYNDFGSYNNQSSNFGPMKGGNFGGRSSGPYGGGESPRGLRAPRGGCTPTPLSLEHFRPPRRLRQLERRRQLRRREEVLTPAGNKA", "length": 403, "header": "tr|A0A8V0ZRC6-1|A0A8V0ZRC6_CHICK Isoform 1 of Heteroous nuclear ribonucleoprotein A1 OS=Gallus gallus OX=9031 GN=HNRNPA1 PE=1 SV=1 CANONICAL=A0A8V0ZRC6-1" }, "locus": { "chromosome": "34", "start_pos": 768153, "end_pos": 762855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054829.1", "url": "https://www.ensembl.org/id/ENSGALT00010054829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033141.1", "url": "https://www.ensembl.org/id/ENSGALP00010033141.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" }, { "id": "R-GGA-9770562", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9770562", "resource": "Reactome", "description": "mRNA Polyadenylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W4Q9-1", "protein_name": "Heteroous nuclear ribonucleoprotein A1", "gene_name": "HNRNPA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF", "length": 373 }, "evidence": [ { "id": "A0A8V0ZRC6", "url": "https://omabrowser.org/oma/group/A0A8V0ZRC6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2M0H3-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF", "length": 373 }, "evidence": [ { "id": "A0A8V0ZRC6", "url": "https://omabrowser.org/oma/group/A0A8V0ZRC6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P04256-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALCKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF", "length": 320 }, "evidence": [ { "id": "A0A8V0ZRC6", "url": "https://omabrowser.org/oma/group/A0A8V0ZRC6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07909-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hrb98DE", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVNSNQNQNGNSNGHDDDFPQDSITEPEHMRKLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPRTKRSRGFGFITYSHSSMIDEAQKSRPHKIDGRVVEPKRAVPRQDIDSPNAGATVKKLFVGALKDDHDEQSIRDYFQHFGNIVDINIVIDKETGKKRGFAFVEFDDYDPVDKVVLQKQHQLNGKMVDVKKALPKQNDQQGGGGGRGGPGGRAGGNRGNMGGGNYGNQNGGGNWNNGGNNWGNNRGGNDNWGNNSFGGGGGGGGGYGGGNNSWGNNNPWDNGNGGGNFGGGGNNWNNGGNDFGGYQQNYGGGPQRGGGNFNNNRMQPYQGGGGFKAGGGNQGNYGGNNQGFNNGGNNRRY", "length": 365 }, "evidence": [ { "id": "A0A8V0ZRC6", "url": "https://omabrowser.org/oma/group/A0A8V0ZRC6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC6" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 97, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 215, "end_pos": 217 }, { "start_pos": 327, "end_pos": 329 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQZ0-1", "uniprot_ac": "A0A8V0ZQZ0", "uniprot_id": "A0A8V0ZQZ0_CHICK", "mass": { "chemical_mass": 60559.0, "monoisotopic_mass": 60559.0 }, "refseq": { "ac": "XP_015148633", "name": "copine-9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148633" }, "gene_names": [ { "name": "CPNE9", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0" } ] }, { "name": "CPNE9", "type": "synonym", "evidence": [ { "id": "XP_015148633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148633" } ] } ], "protein_names": [ { "name": "Copine-9", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0/entry#names_and_taxonomy" } ] }, { "name": "Copine IX", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0/entry#names_and_taxonomy" } ] }, { "name": "copine-9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015148633", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148633" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015148633.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148633" } ] }, { "annotation": "Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes. Plays a role in dendrite formation by melanocytes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZIJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ5#function" }, { "database": "UniProtKB", "id": "ARBA00053866", "url": "https://www.uniprot.org/uniprotkb/ARBA00053866#function" }, { "database": "UniProtKB", "id": "A0A8V0ZQZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CPNE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0", "locus": { "chromosome": "12", "start_pos": 11645222, "end_pos": 11639687, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021512", "url": "https://www.ensembl.org/id/ENSGALG00010021512" } ] } } ], "crossref": [ { "id": "A0A8V0ZQZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04047", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04047", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04048", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04048", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101747832", "url": "https://www.ncbi.nlm.nih.gov/gene/101747832", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101747832", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747832", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DMHATIR", "url": "https://omabrowser.org/oma/group/DMHATIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIJ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZIJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQZ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZQZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857:SF112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857:SF112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148633", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148633", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPGALEAAAGGVPGTKVELTVSCRNLLDMDTFSKSDPVVILFVQGTGSSEWKEFGRTEVIDNTLNPDFVRKFVLDYYFEEKQNLRFDVYNVDSKSCSIYKQKDFLGQAFVALGEVIGSQRGRLERALTGVPGKRCGTILLLAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFATSYRELSRAQSQFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVESEFTFVDYIRGGTQLNFTVAIDFTASNGLPSQPTSLHYASPYQLSAYALALKAVGEIIQDYDSDKLFPAYGFGAKLPPDGKISHQFPLNNNVDNPSCAGIEGVLESYLQSLRTVQLYGPTNFAPVINQVAGTAAQVTDGSQYHVLLIITDGVISDMMQTKEAIVTASALPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRYAERDIVQFVPFRDYVDEAGSQVRSMARLAKDVLAEIPEQLLSYMRGRGIEPRRNAAQ", "length": 546, "header": "tr|A0A8V0ZQZ0-1|A0A8V0ZQZ0_CHICK Isoform 1 of Copine-9 OS=Gallus gallus OX=9031 GN=CPNE9 PE=3 SV=1 CANONICAL=A0A8V0ZQZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0/entry#A0A8V0ZIJ5-1", "sequence": { "sequence": "MAAPGALEAAAGGVPGTKVELTVSCRNLLDMDTFSKSDPVVILFVQGTGSSEWKEFGRTEVIDNTLNPDFVRKFVLDYYFEEKQNLRFDVYNVDSKSCSIYKQDFLGQAFVALGEVIGSQRGRLERALTGVPGKRCGTILLLAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFATSYRELSRAQSQFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVESEFTFVDYIRGGTQLNFTVAIDFTASNGLPSQPTSLHYASPYQLSAYALALKAVGEIIQDYDSDKLFPAYGFGAKLPPDGKISHQFPLNNNVDNPSCAGIEGVLESYLQSLRTVQLYGPTNFAPVINQVAGTAAQVTDGSQYHVLLIITDGVISDMMQTKEAIVTASALPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRYAERDIVQFVPFRDYVDEAGSQVRSMARLAKDVLAEIPEQLLSYMRGRGIEPRRNAAQ", "length": 545, "header": "tr|A0A8V0ZIJ5-1|A0A8V0ZQZ0_CHICK Computationally mapped isoform of Copine-9 OS=Gallus gallus OX=9031 GN=CPNE9 PE=3 SV=1 CANONICAL=A0A8V0ZQZ0-1" }, "locus": { "chromosome": "12", "start_pos": 11645134, "end_pos": 11639725, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052169.1", "url": "https://www.ensembl.org/id/ENSGALT00010052169.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031156.1", "url": "https://www.ensembl.org/id/ENSGALP00010031156.1" } ] } }, { "isoform_ac": "A0A8V0ZQZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0/entry#A0A8V0ZQZ0-1", "sequence": { "sequence": "MAAPGALEAAAGGVPGTKVELTVSCRNLLDMDTFSKSDPVVILFVQGTGSSEWKEFGRTEVIDNTLNPDFVRKFVLDYYFEEKQNLRFDVYNVDSKSCSIYKQKDFLGQAFVALGEVIGSQRGRLERALTGVPGKRCGTILLLAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFATSYRELSRAQSQFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVESEFTFVDYIRGGTQLNFTVAIDFTASNGLPSQPTSLHYASPYQLSAYALALKAVGEIIQDYDSDKLFPAYGFGAKLPPDGKISHQFPLNNNVDNPSCAGIEGVLESYLQSLRTVQLYGPTNFAPVINQVAGTAAQVTDGSQYHVLLIITDGVISDMMQTKEAIVTASALPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRYAERDIVQFVPFRDYVDEAGSQVRSMARLAKDVLAEIPEQLLSYMRGRGIEPRRNAAQ", "length": 546, "header": "tr|A0A8V0ZQZ0-1|A0A8V0ZQZ0_CHICK Isoform 1 of Copine-9 OS=Gallus gallus OX=9031 GN=CPNE9 PE=3 SV=1 CANONICAL=A0A8V0ZQZ0-1" }, "locus": { "chromosome": "12", "start_pos": 11645134, "end_pos": 11639725, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052166.1", "url": "https://www.ensembl.org/id/ENSGALT00010052166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031155.1", "url": "https://www.ensembl.org/id/ENSGALP00010031155.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:101747832", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101747832", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TYT0-1", "protein_name": "Copine-9", "gene_name": "CPNE9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSFSGASERSVPATKIEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGSRVERPLTGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCVGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQPRPPPPATTSPTPAPEHP", "length": 553 }, "evidence": [ { "id": "A0A8V0ZQZ0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q1RLL3-1", "protein_name": "Copine-9", "gene_name": "Cpne9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLSGASERSVPATKIEITVSCRNLLDLDTFSKSDPMVVLHTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKDFLGQAFLALGEVIGGQGSRVERPLTGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQPRPPPPVSPNPTPAPEQP", "length": 553 }, "evidence": [ { "id": "A0A8V0ZQZ0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5BJS7-1", "protein_name": "Copine-9", "gene_name": "Cpne9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLGGASERSVPATKIEITVSCRNLLDLDTFSKSDPMVVLHTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKDFLGQAFLALGEVIGGQGSRVERPLTGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQPRPPPPANPNPTSAPEQP", "length": 553 }, "evidence": [ { "id": "A0A8V0ZQZ0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IYJ1-1", "protein_name": "Copine-9", "gene_name": "CPNE9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLGGASERSVPATKIEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVRKFVLDYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGSRVERTLTGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRDGSHDFIGEFTTSYRELSKAQNQFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYVDRSGNQVLSMARLAKDVLAEIPEQLLSYMRTRDIQPRPPPPANPSPIPAPEQP", "length": 553 }, "evidence": [ { "id": "A0A8V0ZQZ0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q941L3-1", "protein_name": "Protein BONZAI 1", "gene_name": "BON1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGNCCSDVASGAGATAGVGGSGSSAALGATNDALDYYLKSKGFNGLFSQIELSFSASNLRDRDVLSKSDPMVVVYQKEKDATLSEVFRSEVVLNSLAPKWIKKFIVAYHFETVQTLVFRVYDVDTKFQNSREEMLKLDEQQFLGEATCALSEIITKSTRTSTLELKRKDGFAPQAQPHHGKLIIHAEESLASKISTEIVFRCSNLESKDLFSKSDPFLVVSKIVEHGTPIPVSKTEVRKNDLNPIWKPVFLSVQQVGSKDSPVIIECSDFNSNGKHSLIGKVQKSLSDLEKLHLAGQGINFSLPTGAGQNKVLKSQLFVDKFTETVHHTFLEYLASGFELNFMVAIDFTASNGNPRLPDSLHYIDPSGRLNAYQRAIMDVGEVLQFYDSDKRFPAWGFGARPIDAPVSHCFNLNGSSSYSEVDGIQGIMTSYTSALFNVSLAGPTLFGPVINAAAMIASASLAQGSRKYYVLLIITDGVITDLQETKDALVSASDLPLSILIVGVGGADFKEMEILDADKGERLESSSGRLASRDIVQFVALRDVQYGEISVVQALLAELPSQFLTYMRIRNMKPIPP", "length": 578 }, "evidence": [ { "id": "A0A8V0ZQZ0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0" } ], "pmid": "" }, { "name": "positive regulation of dendrite extension", "id": "GO:1903861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0" } ], "pmid": "" }, { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 127, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQZ0" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 303, "end_pos": 507, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 303, "end_pos": 305 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZR14-1", "uniprot_ac": "A0A8V0ZR14", "uniprot_id": "A0A8V0ZR14_CHICK", "mass": { "chemical_mass": 36580.0, "monoisotopic_mass": 36580.0 }, "refseq": {}, "gene_names": [ { "name": "RAB15", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR14" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR14/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR14/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR14" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB15", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR14", "locus": { "chromosome": "5", "start_pos": 528958, "end_pos": 526115, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021531", "url": "https://www.ensembl.org/id/ENSGALG00010021531" } ] } } ], "crossref": [ { "id": "A0A8V0ZR14", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR14", "database": "AlphaFoldDB", "categories": [] }, { "id": "429955", "url": "https://www.ncbi.nlm.nih.gov/gene/429955", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIL4", "url": "https://www.orthodb.org/?gene=A0A8V0ZIL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR14", "url": "https://www.orthodb.org/?gene=A0A8V0ZR14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47980", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47980", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZIL4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PVSRGSKPACACPPGAPLTRCCTPVVPPQCRGCISRCPAVHLRSIRPSAASRRPGTSHAVPIGVPHCIPVCPSPCPHPSLTSPAPNSRLLIVSPTPPPGIPTTPPEDPDAPPGVLPRSPGCPLLCPLHPPLQNRVCLRLAPPRRVPHCLPPTPTPIPIPPASPSRYPAHPRAPPRCHPAGSPPPARRRRQAAMAKQYDVLFRLLLLGDSGVGKTCLLCRFTDSEFHPAHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIVKWASDVDEYAPDGVQKILIGNKADEEHKSLPGSTGWTSMRPVPAAT", "length": 338, "header": "tr|A0A8V0ZR14-1|A0A8V0ZR14_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB15 PE=3 SV=1 CANONICAL=A0A8V0ZR14-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR14/entry#A0A8V0ZIL4-1", "sequence": { "sequence": "MGERETGSDGRWENGKPGAPGGVDFKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIVKWASDVDEYAPDGVQKILIGNKADEEHKRQVAKEQGLQLAREYGMDFYETSACSNLNIKESFTRLTELVLQAHRKELEGLRTATAPPELAQLEEDEQQTPGGHDNPKNCWC", "length": 191, "header": "tr|A0A8V0ZIL4-1|A0A8V0ZR14_CHICK Computationally mapped isoform of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB15 PE=3 SV=1 CANONICAL=A0A8V0ZR14-1" }, "locus": { "chromosome": "5", "start_pos": 528768, "end_pos": 527063, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052209.1", "url": "https://www.ensembl.org/id/ENSGALT00010052209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031181.1", "url": "https://www.ensembl.org/id/ENSGALP00010031181.1" } ] } }, { "isoform_ac": "A0A8V0ZR14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR14/entry#A0A8V0ZR14-1", "sequence": { "sequence": "PVSRGSKPACACPPGAPLTRCCTPVVPPQCRGCISRCPAVHLRSIRPSAASRRPGTSHAVPIGVPHCIPVCPSPCPHPSLTSPAPNSRLLIVSPTPPPGIPTTPPEDPDAPPGVLPRSPGCPLLCPLHPPLQNRVCLRLAPPRRVPHCLPPTPTPIPIPPASPSRYPAHPRAPPRCHPAGSPPPARRRRQAAMAKQYDVLFRLLLLGDSGVGKTCLLCRFTDSEFHPAHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIVKWASDVDEYAPDGVQKILIGNKADEEHKSLPGSTGWTSMRPVPAAT", "length": 338, "header": "tr|A0A8V0ZR14-1|A0A8V0ZR14_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB15 PE=3 SV=1 CANONICAL=A0A8V0ZR14-1" }, "locus": { "chromosome": "5", "start_pos": 528537, "end_pos": 526117, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052214.1", "url": "https://www.ensembl.org/id/ENSGALT00010052214.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031186.1", "url": "https://www.ensembl.org/id/ENSGALP00010031186.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 152, "start_aa": "Thr", "end_pos": 152, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr152", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", 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"table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQV7-1", "uniprot_ac": "A0A8V0ZQV7", "uniprot_id": "A0A8V0ZQV7_CHICK", "mass": { "chemical_mass": 133762.0, "monoisotopic_mass": 133762.0 }, "refseq": {}, "gene_names": [ { "name": "FAM65A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ] } ], "protein_names": [ { "name": "Rho family-interacting cell polarization regulator 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7#function" }, { "database": "UniProtKB", "id": "ARBA00054594", "url": "https://www.uniprot.org/uniprotkb/ARBA00054594#function" }, { "database": "UniProtKB", "id": "A0A8V0ZIP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZIQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZP20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP20#function" }, { "database": "UniProtKB", "id": "A0A8V0ZQY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZRK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK0#function" }, { "database": "UniProtKB", "id": "A0A8V0ZWJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM65A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZQV7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "415665", "url": "https://www.ncbi.nlm.nih.gov/gene/415665", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIP5", "url": "https://www.orthodb.org/?gene=A0A8V0ZIP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIQ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZIQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP20", "url": "https://www.orthodb.org/?gene=A0A8V0ZP20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQV7", "url": "https://www.orthodb.org/?gene=A0A8V0ZQV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQY0", "url": "https://www.orthodb.org/?gene=A0A8V0ZQY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRK0", "url": "https://www.orthodb.org/?gene=A0A8V0ZRK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWI5", "url": "https://www.orthodb.org/?gene=A0A8V0ZWI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWJ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZWJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZIP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP20", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRK0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASCPACTEQGSPRAPCPQGLGLSCLGMSILGEKVAPGTFVRFCHPHHDPEALGKGVPHPYPGDTERSYGPPPPEWMGIAVGAPTPRPCPPPGDPSRWVRRLHGHIPGDALENRSCSNHPLRRPPPWVPPRGWHLPSGIHRVPRDVLRGAPSPSHCVSSPALPFLGDAPRGRPSRSHSTMSLSARPQRRVLVAKINRSQSFAGVNSTAERPFSRNLSPFTPTVSRKTGSRVSRMFSMSHKSPPPKVPQPNRLDEVYEALKKGLTAYLEVHQLELEKLSTQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCIQRRLRDGAHNMVKAYSTGSPGSREARESLAEASKGYKEYTENMCLLESELESQLGEFHVRMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEVNSKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGNVSCETKDLFAALPQVVAVDINDLGTLKLSLEVTWNPFDKDDQPSAASTVNKASTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEELENGTAWSISSESSDDSSSPQLSSSTRHAAHKPIVQPEVQASAPAIEISFSQQQEETGAGGGIPAGTDLPGPPEEQDGRRKDAVANGHVPYTRTLSHISEASVDASMEAKATESPWEPSPSLEEHDVGKLDDDSLPGASNSVPETWAGKDSGPEAKPRAMVAWAATCEVEAEAAASHAAAQDVCGSEAPTPAVVLAQAPAEEGHVPAPHLATSPPAVPRVKAVDSGLEEAISLLASALDDYRGQFPELQPLERELKHLEEILLHKQGVFLSRASSISLTVEHALESFSFLNTSDMEDSEGSEEEALQDERRASRARRGSRAASAGEVGADDTGTCSGSEGSADPMSTGNEFLDKALVLHLHNCNHLLLNLGTFGPLRCREMFALDRLLREAQVLEIVCQLMEERSEAAGSAAGVVQFSTRKEGVLPLWDHCVELPNIYTCPVERFLQVLSAQYAAPISERHPGLADAVCVKLVEDVLNRRLPRRPGGTQGEQVTIFQYWSHFEALGALVLDTYVMELAEEVLLAQNLNSDDQDVVLRALKRVPEGRLKKEGLKALSLLLVEGNSKVVSAVSAQLRSLAENPRFRQRALVCFLGQLEDEEVQTRVAGCVALGCLKAKESIEQLVYLCQTDKEPVREAAKQSLMLCGEDGKSAHRRLEETLDSLPRIFAPASMASTAF", "length": 1222, "header": "tr|A0A8V0ZQV7-1|A0A8V0ZQV7_CHICK Isoform 1 of Rho family-interacting cell polarization regulator 1 OS=Gallus gallus OX=9031 GN=FAM65A PE=3 SV=1 CANONICAL=A0A8V0ZQV7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZIP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7/entry#A0A8V0ZIP5-1", "sequence": { "sequence": "MSLSARPQRRVLVAKINRSQSFAGVNSTAERPFRNLSPFTPTVSRKTGSRVSRMFSMSHKSPPPKVPQPNRLDEVYEALKKGLTAYLEVHQLELEKLSTQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCIQRRLRDGAHNMVKAYSTGSPGSREARESLAEASKGYKEYTENMCLLESELESQLGEFHVRMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEVNSKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGNVSCETKDLFAALPQVVAVDINDLGTLKLSLEVTWNPFDKDDQPSAASTVNKASTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEELENGTAWSISSESSDDSSSPQLSSSTRHAAHKPIVQPEVQASAPAIEISFSQQQEETGAGGGIPAGTDLPGPPEEQDGRRKDAVANGHVPYTRTLSHISEASVDASMEAKATESPWEPSPSLEEHDVGKLDDDSLPGASNSVPETWAGKDSGPEAKPRAMVAWAATCEVEAEAAASHAAAQDVCGSEAPTPAVVLAQAPAEEGHVPAPHLATSPPAVPRVKAVDSGLEEAISLLASALDDYRGQFPELQPLERELKHLEEILLHKQGVFLSRASSISLTVEHALESFSFLNTSDMEDSEGSEEEALQDERRASRARRGSRAASAGEVGADDTGTCSGSEGSADPMSTGNEFLDKALVLHLHNCNHLLLNLGTFGPLRCREMFALDRLLREAQVLEIVCQLMEERSEAAGSAAGVVQFSTRKEGVLPLWDHCVELPNIYTCPVERFLQVLSAQYAAPISERHPGLADAVCVKLVEDVLNRRLPRRPGGTQGEQVTIFQYWSHFEALGALVLDTYVMELAEEVLLAQNLNSDDQDVVLRALKRVPEGRLKKEGLKALSLLLVEGNSKVVSAVSAQLRSLAENPRFRQRALVCFLGQLEDEEVQTRVAGCVALGCLKAKESIEQLVYLCQTDKEPVREAAKQSLMLCGEDGKSAHRRLEETLDSLPRIFAPASMASTAF", "length": 1042, "header": "tr|A0A8V0ZIP5-1|A0A8V0ZQV7_CHICK Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Gallus gallus OX=9031 GN=FAM65A PE=3 SV=1 CANONICAL=A0A8V0ZQV7-1" }, "locus": { "chromosome": "11", "start_pos": 1123404, "end_pos": 1112647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054936.1", "url": "https://www.ensembl.org/id/ENSGALT00010054936.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033214.1", "url": "https://www.ensembl.org/id/ENSGALP00010033214.1" } ] } }, { "isoform_ac": "A0A8V0ZIQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7/entry#A0A8V0ZIQ8-1", "sequence": { "sequence": "MGEEQRRCAQPGPLPSHASPGTWRPSRSHSTMSLSARPQRRVLVAKINRSQSFAGVNSTAERPFRNLSPFTPTVSRKTGSRVSRMFSMSHKSPPPKVPQPNRLDEVYEALKKGLTAYLEVHQLELEKLSTQIRESKRNSRLQVKSIERFLRRLEFHASKIDELYEAYCIQRRLRDGAHNMVKAYSTGSPGSREARESLAEASKGYKEYTENMCLLESELESQLGEFHVRMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEVNSKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGNVSCETKDLFAALPQVVAVDINDLGTLKLSLEVTWNPFDKDDQPSAASTVNKASTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEELENGTAWSISSESSDDSSSPQLSSSTRHAAHKPIVQPEVQASAPAIEISFSQQQEETGAGGGIPAGTDLPGPPEEQDGRRKDAVANGHVPYTRTLSHISEASVDASMEAKATESPWEPSPSLEEHDVGKLDDDSLPGASNSVPETWAGKDSGPEAKPRAMVAWAATCEVEAEAAASHAAAQDVCGSEAPTPAVVLAQAPAEEGHVPAPHLATSPPAVPRVKAVDSGLEEAISLLASALDDYRGQFPELQPLERELKHLEEILLHKQGVFLSRASSISLTVEHALESFSFLNTSDMEDSEGSEEEALQDERRASRARRGSRAASAGEVGADDTGTCSGSEGSADPMSTGNEFLDKALVLHLHNCNHLLLNLGTFGPLRCREMFALDRLLREAQVLEIVCQLMEERSEAAGSAAGVVQFSTRKEGVLPLWDHCVELPNIYTCPVERFLQVLSAQYAAPISERHPGLADAVCVKLVEDVLNRRLPRRPGGTQGEQVTIFQYWSHFEALGALVLDTYVMELAEEVLLAQNLNSDDQDVVLRALKRVPEGRLKKEGLKALSLLLVEGNSKVVSAVSAQLRSLAENPRFRQRALVCFLGQLEDEEVQTRVAGCVALGCLKAKESIEQLVYLCQTDKEPVREAAKQSLMLCGEDGKSAHRRLEETLDSLPRIFAPASMASTAF", "length": 1065, "header": "tr|A0A8V0ZIQ8-1|A0A8V0ZQV7_CHICK Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Gallus gallus OX=9031 GN=FAM65A PE=3 SV=1 CANONICAL=A0A8V0ZQV7-1" }, "locus": { "chromosome": "11", "start_pos": 1123404, "end_pos": 1105539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054961.1", "url": "https://www.ensembl.org/id/ENSGALT00010054961.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033230.1", "url": "https://www.ensembl.org/id/ENSGALP00010033230.1" } ] } }, { "isoform_ac": "A0A8V0ZP20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7/entry#A0A8V0ZP20-1", "sequence": { "sequence": "MNDKQRGRPSRSHSTMSLSARPQRRVLVAKINRSQSFAGVNSTAERPFSRNLSPFTPTVSRKTGSRVSRMFSMSHKSPPPKVPQPNRLDEVYEALKKGLTAYLEVHQLELEKLSTQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCIQRRLRDGAHNMVKAYSTGSPGSREARESLAEASKGYKEYTENMCLLESELESQLGEFHVRMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEVNSKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGNVSCETKDLFAALPQVVAVDINDLGTLKLSLEVTWNPFDKDDQPSAASTVNKASTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEELENGTAWSISSESSDDSSSPQLSSSTRHAAHKPIVQPEVQASAPAIEISFSQQQEETGAGGGIPAGTDLPGPPEEQDGRRKDAVANGHVPYTRTLSHISEASVDASMEAKATESPWEPSPSLEEHDVGKLDDDSLPGASNSVPETWAGKDSGPEAKPRAMVAWAATCEVEAEAAASHAAAQDVCGSEAPTPAVVLAQAPAEEGHVPAPHLATSPPAVPRVKAVDSGLEEAISLLASALDDYRGQFPELQPLERELKHLEEILLHKQGVFLSRASSISLTVEHALESFSFLNTSDMEDSEGSEEEALQDERRASRARRGSRAASAGEVGADDTGTCSGSEGSADPMSTGNEFLDKALVLHLHNCNHLLLNLGTFGPLRCREMFALDRLLREAQVLEIVCQLMEERSEAAGSAAGVVQFSTRKEGVLPLWDHCVELPNIYTCPVERFLQVLSAQYAAPISERHPGLADAVCVKLVEDVLNRRLPRRPGGTQGEQVTIFQYWSHFEALGALVLDTYVMELAEEVLLAQNLNSDDQDVVLRALKRVPEGRLKKEGLKALSLLLVEGNSKVVSAVSAQLRSLAENPRFRQRALVCFLGQLEDEEVQTRVAGCVALGCLKAKESIEQLVYLCQTDKEPVREAAKQSLMLCGEDGKSAHRRLEETLDSLPRIFAPASMASTAF", "length": 1058, "header": "tr|A0A8V0ZP20-1|A0A8V0ZP20_CHICK Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Gallus gallus OX=9031 GN=FAM65A PE=3 SV=1 CANONICAL=A0A8V0ZQV7-1" }, "locus": { "chromosome": "11", "start_pos": 1123404, "end_pos": 1108656, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054948.1", "url": "https://www.ensembl.org/id/ENSGALT00010054948.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033221.1", "url": "https://www.ensembl.org/id/ENSGALP00010033221.1" } ] } }, { "isoform_ac": "A0A8V0ZQV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7/entry#A0A8V0ZQV7-1", "sequence": { "sequence": "MASCPACTEQGSPRAPCPQGLGLSCLGMSILGEKVAPGTFVRFCHPHHDPEALGKGVPHPYPGDTERSYGPPPPEWMGIAVGAPTPRPCPPPGDPSRWVRRLHGHIPGDALENRSCSNHPLRRPPPWVPPRGWHLPSGIHRVPRDVLRGAPSPSHCVSSPALPFLGDAPRGRPSRSHSTMSLSARPQRRVLVAKINRSQSFAGVNSTAERPFSRNLSPFTPTVSRKTGSRVSRMFSMSHKSPPPKVPQPNRLDEVYEALKKGLTAYLEVHQLELEKLSTQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCIQRRLRDGAHNMVKAYSTGSPGSREARESLAEASKGYKEYTENMCLLESELESQLGEFHVRMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEVNSKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGNVSCETKDLFAALPQVVAVDINDLGTLKLSLEVTWNPFDKDDQPSAASTVNKASTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEELENGTAWSISSESSDDSSSPQLSSSTRHAAHKPIVQPEVQASAPAIEISFSQQQEETGAGGGIPAGTDLPGPPEEQDGRRKDAVANGHVPYTRTLSHISEASVDASMEAKATESPWEPSPSLEEHDVGKLDDDSLPGASNSVPETWAGKDSGPEAKPRAMVAWAATCEVEAEAAASHAAAQDVCGSEAPTPAVVLAQAPAEEGHVPAPHLATSPPAVPRVKAVDSGLEEAISLLASALDDYRGQFPELQPLERELKHLEEILLHKQGVFLSRASSISLTVEHALESFSFLNTSDMEDSEGSEEEALQDERRASRARRGSRAASAGEVGADDTGTCSGSEGSADPMSTGNEFLDKALVLHLHNCNHLLLNLGTFGPLRCREMFALDRLLREAQVLEIVCQLMEERSEAAGSAAGVVQFSTRKEGVLPLWDHCVELPNIYTCPVERFLQVLSAQYAAPISERHPGLADAVCVKLVEDVLNRRLPRRPGGTQGEQVTIFQYWSHFEALGALVLDTYVMELAEEVLLAQNLNSDDQDVVLRALKRVPEGRLKKEGLKALSLLLVEGNSKVVSAVSAQLRSLAENPRFRQRALVCFLGQLEDEEVQTRVAGCVALGCLKAKESIEQLVYLCQTDKEPVREAAKQSLMLCGEDGKSAHRRLEETLDSLPRIFAPASMASTAF", "length": 1222, "header": "tr|A0A8V0ZQV7-1|A0A8V0ZQV7_CHICK Isoform 1 of Rho family-interacting cell polarization regulator 1 OS=Gallus gallus OX=9031 GN=FAM65A PE=3 SV=1 CANONICAL=A0A8V0ZQV7-1" }, "locus": { "chromosome": "11", "start_pos": 1123404, "end_pos": 1109178, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054942.1", "url": "https://www.ensembl.org/id/ENSGALT00010054942.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033218.1", "url": "https://www.ensembl.org/id/ENSGALP00010033218.1" } ] } }, { "isoform_ac": "A0A8V0ZQY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7/entry#A0A8V0ZQY0-1", "sequence": { "sequence": "MSLSARPQRRVLVAKINRSQSFAGVNSTAERPFRNLSPFTPTVSRKTGSRVSRMFSMSHKSPPPKVPQPNRLDEVYEALKKGLTAYLEVHQLELEKLSTQIRESKRNSRLGFLYDLDKPASWDTSYPTAGAWGRAISWPAAPLREPLTPSLLFQQVKSIERFLRRLEFHASKIDELYEAYCIQRRLRDGAHNMVKAYSTGSPGSREARESLAEASKGYKEYTENMCLLESELESQLGEFHVRMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEVNSKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGNVSCETKDLFAALPQVVAVDINDLGTLKLSLEVTWNPFDKDDQPSAASTVNKASTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEELENGTAWSISSESSDDSSSPQLSSSTRHAAHKPIVQPEVQASAPAIEISFSQQQEETGAGGGIPAGTDLPGPPEEQDGRRKDAVANGHVPYTRTLSHISEASVDASMEAKATESPWEPSPSLEEHDVGKLDDDSLPGASNSVPETWAGKDSGPEAKPRAMVAWAATCEVEAEAAASHAAAQDVCGSEAPTPAVVLAQAPAEEGHVPAPHLATSPPAVPRVKAVDSGLEEAISLLASALDDYRGQFPELQPLERELKHLEEILLHKQGVFLSRASSISLTVEHALESFSFLNTSDMEDSEGSEEEALQDERRASRARRGSRAASAGEVGADDTGTCSGSEGSADPMSTGNEFLDKALVLHLHNCNHLLLNLGTFGPLRCREMFALDRLLREAQVLEIVCQLMEERSEAAGSAAGVVQFSTRKEGVLPLWDHCVELPNIYTCPVERFLQVLSAQYAAPISERHPGLADAVCVKLVEDVLNRRLPRRPGGTQGEQVTIFQYWSHFEALGALVLDTYVMELAEEVLLAQNLNSDDQDVVLRALKRVPEGRLKKEGLKALSLLLVEGNSKVVSAVSAQLRSLAENPRFRQRALVCFLGQLEDEEVQTRVAGCVALGCLKAKESIEQLVYLCQTDKEPVREAAKQSLMLCGEDGKSAHRRLEETLDSLPRIFAPASMASTAF", "length": 1078, "header": "tr|A0A8V0ZQY0-1|A0A8V0ZQY0_CHICK Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Gallus gallus OX=9031 GN=FAM65A PE=3 SV=1 CANONICAL=A0A8V0ZQV7-1" }, "locus": { "chromosome": "11", "start_pos": 1123404, "end_pos": 1112647, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054974.1", "url": "https://www.ensembl.org/id/ENSGALT00010054974.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033239.1", "url": "https://www.ensembl.org/id/ENSGALP00010033239.1" } ] } }, { "isoform_ac": "A0A8V0ZRK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7/entry#A0A8V0ZRK0-1", "sequence": { "sequence": "MATSWRSRGRPSRSHSTMSLSARPQRRVLVAKINRSQSFAGVNSTAERPFRNLSPFTPTVSRKTGSRVSRMFSMSHKSPPPKVPQPNRLDEVYEALKKGLTAYLEVHQLELEKLSTQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCIQRRLRDGAHNMVKAYSTGSPGSREARESLAEASKGYKEYTENMCLLESELESQLGEFHVRMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEVNSKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGNVSCETKDLFAALPQVVAVDINDLGTLKLSLEVTWNPFDKDDQPSAASTVNKASTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEELENGTAWSISSESSDDSSSPQLSSSTRHAAHKPIVQPEVQASAPAIEISFSQQQEETGAGGGIPAGTDLPGPPEEQDGRRKDAVANGHVPYTRTLSHISEASVDASMEAKATESPWEPSPSLEEHDVGKLDDDSLPGASNSVPETWAGKDSGPEAKPRAMVAWAATCEVEAEAAASHAAAQDVCGSEAPTPAVVLAQAPAEEGHVPAPHLATSPPAVPRVKAVDSGLEEAISLLASALDDYRGQFPELQPLERELKHLEEILLHKQGVFLSRASSISLTVEHALESFSFLNTSDMEDSEGSEEEALQDERRASRARRGSRAASAGEVGADDTGTCSGSEGSADPMSTGNEFLDKALVLHLHNCNHLLLNLGTFGPLRCREMFALDRLLREAQVLEIVCQLMEERSEAAGSAAGVVQFSTRKEGVLPLWDHCVELPNIYTCPVERFLQVLSAQYAAPISERHPGLADAVCVKLVEDVLNRRLPRRPGGTQGEQVTIFQYWSHFEALGALVLDTYVMELAEEVLLAQNLNSDDQDVVLRALKRVPEGRLKKEGLKALSLLLVEGNSKVVSAVSAQLRSLAENPRFRQRALVCFLGQLEDEEVQTRVAGCVALGCLKAKESIEQLVYLCQTDKEPVREAAKQSLMLCGEDGKSAHRRLEETLDSLPRIFAPASMASTAF", "length": 1059, "header": "tr|A0A8V0ZRK0-1|A0A8V0ZRK0_CHICK Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Gallus gallus OX=9031 GN=FAM65A PE=3 SV=1 CANONICAL=A0A8V0ZQV7-1" }, "locus": { "chromosome": "11", "start_pos": 1123404, "end_pos": 1112481, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054934.1", "url": "https://www.ensembl.org/id/ENSGALT00010054934.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033212.1", "url": "https://www.ensembl.org/id/ENSGALP00010033212.1" } ] } }, { "isoform_ac": "A0A8V0ZWI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7/entry#A0A8V0ZWI5-1", "sequence": { "sequence": "MGEEQRRCAQPGPLPSHASPGTWRPSRSHSTMSLSARPQRRVLVAKINRSQSFAGVNSTAERPFRNLSPFTPTVSRKTGSRVSRMFSMSHKSPPPKVPQPNRLDEVYEALKKGLTAYLEVHQLELEKLSTQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCIQRRLRDGAHNMVKAYSTGSPGSREARESLAEASKGYKEYTENMCLLESELESQLGEFHVRMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEVNSKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGNVSCETKDLFAALPQVVAVDINDLGTLKLSLEVTWNPFDKDDQPSAASTVNKASTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEELENGTAWSISSESSDDSSSPQLSSSTRHAAHKPIVQPEVQASAPAIEISFSQQQEETGAGGGIPAGTDLPGPPEEQDGRRKDAVANGHVPYTRTLSHISEASVDASMEAKATESPWEPSPSLEEHDVGKLDDDSLPGASNSVPETWAGKDSGPEAKPRAMVAWAATCEVEAEAAASHAAAQDVCGSEAPTPAVVLAQAPAEEGHVPAPHLATSPPAVPRVKAVDSGLEEAISLLASALDDYRGQFPELQPLERELKHLEEILLHKQGVFLSRASSISLTVEHALESFSFLNTSDMEDSEGSEEEALQDERRASRARRGSRAASAGEVGADDTGTCSGSEGSADPMSTGNEFLDKALVLHLHNCNHLLLNLGTFGPLRCREMFALDRLLREAQVLEIVCQLMEERSEAAGSAAGVVQFSTRKEGVLPLWDHCVELPNIYTCPVERFLQVLSAQYAAPISERHPGLADAVCVKLVEDVLNRRLPRRPGGTQGEQVTIFQYWSHFEALGALVLDTYVMELAEEVLLAQNLNSDDQDVVLRALKRVPEGRLKKEGLKALSLLLVEGNSKVVSAVSAQLRSLAENPRFRQRALVCFLGQLEDEEVQTRVAGCVALGCLKAKESIEQLVYLCQTDKEPVREAAKQSLMLYGTERTI", "length": 1047, "header": "tr|A0A8V0ZWI5-1|A0A8V0ZQV7_CHICK Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Gallus gallus OX=9031 GN=FAM65A PE=3 SV=1 CANONICAL=A0A8V0ZQV7-1" }, "locus": { "chromosome": "11", "start_pos": 1122529, "end_pos": 1105539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054953.1", "url": "https://www.ensembl.org/id/ENSGALT00010054953.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033226.1", "url": "https://www.ensembl.org/id/ENSGALP00010033226.1" } ] } }, { "isoform_ac": "A0A8V0ZWJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7/entry#A0A8V0ZWJ6-1", "sequence": { "sequence": "MGEEQRRCAQPGPLPSHASPGTWRPSRSHSTMSLSARPQRRVLVAKINRSQSFAGVNSTAERPFSRNLSPFTPTVSRKTGSRVSRMFSMSHKSPPPKVPQPNRLDEVYEALKKGLTAYLEVHQLELEKLSTQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCIQRRLRDGAHNMVKAYSTGSPGSREARESLAEASKGYKEYTENMCLLESELESQLGEFHVRMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEVNSKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGNVSCETKDLFAALPQVVAVDINDLGTLKLSLEVTWNPFDKDDQPSAASTVNKASTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEELENGTAWSISSESSDDSSSPQLSSSTRHAAHKPIVQPEVQASAPAIEISFSQQQEETGAGGGIPAGTDLPGPPEEQDGRRKDAVANGHVPYTRTLSHISEASVDASMEAKATESPWEPSPSLEEHDVGKLDDDSLPGASNSVPETWAGKDSGPEAKPRAMVAWAATCEVEAEAAASHAAAQDVCGSEAPTPAVVLAQAPAEEGHVPAPHLATSPPAVPRVKAVDSGLEEAISLLASALDDYRGQFPELQPLERELKHLEEILLHKQGVFLSRASSISLTVEHALESFSFLNTSDMEDSEGSEEEALQDERRASRARRGSRAASAGEVGADDTGTCSGSEGSADPMSTGNEFLDKALVLHLHNCNHLLLNLGTFGPLRCREMFALDRLLREAQVLEIVCQLMEERSEAAGSAAGVVQFSTRKEGVLPLWDHCVELPNIYTCPVERFLQVLSAQYAAPISERHPGLADAVCVKLVEDVLNRRLPRRPGGTQGEQVTIFQYWSHFEALGALVLDTYVMELAEEVLLAQNLNSDDQDVVLRALKRVPEGRLKKEGLKALSLLLVEGNSKVVSAVSAQLRSLAENPRFRQRALVCFLGQLEDEEVQTRVAGCVALGCLKAKESIEQLVYLCQTDKEPVREAAKQSLMLCGEDGKSAHRRLEETLDSLPRIFAPASMASTAF", "length": 1074, "header": "tr|A0A8V0ZWJ6-1|A0A8V0ZQV7_CHICK Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Gallus gallus OX=9031 GN=FAM65A PE=3 SV=1 CANONICAL=A0A8V0ZQV7-1" }, "locus": { "chromosome": "11", "start_pos": 1123404, "end_pos": 1105539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054969.1", "url": "https://www.ensembl.org/id/ENSGALT00010054969.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033236.1", "url": "https://www.ensembl.org/id/ENSGALP00010033236.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 736, "start_aa": "Thr", "end_pos": 736, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr736", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" }, { "name": "positive regulation of intracellular protein transport", "id": "GO:0090316", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090316", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" }, { "name": "response to wounding", "id": "GO:0009611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009611", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" }, { "name": "establishment of Golgi localization", "id": "GO:0051683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051683", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" }, { "name": "protein localization to Golgi apparatus", "id": "GO:0034067", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034067", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "14-3-3 protein binding", "id": "GO:0071889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071889", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, 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11973925, "end_pos": 11951787, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051692.1", "url": "https://www.ensembl.org/id/ENSGALT00010051692.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030831.1", "url": "https://www.ensembl.org/id/ENSGALP00010030831.1" } ] } }, { "isoform_ac": "A0A8V0ZQ18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ18/entry#A0A8V0ZQ18-1", "sequence": { "sequence": "MYRAAQEMMRNKRPALDPCSAYISLNEPWRNTDHQINGSHGQPTCDNQIDGEWYRFTGMAGDAMPTFCIPENHCGTHAPIWLNGSHPRESDGIVSRQACASFNGNCCLWNTTIEVKACPGGYYVYHLTKPSVCFHAYCGHFYDICDVVDCQGSCLDTNDCTCSPGTTLGPDGQTCLDENECEQDNGGCSEFCVNLKNSFRCECGIGRTLGSDGKTCEEIEGCHNNNGGCSHTCIEVEDTYQCECPRGLVLSEDNHTCQVPVLCKSSSIEVSIPKDLVGGLDLSLINTSCKGVSNGTHVNIHFSLKSCGTVVDVINDKIIATNLVTGLPKQTPGSNGDIIVRTSKLLIPVTCEFPRRYTISEGYVPNLKNSPLEIMSRNRGIFPFTLEIFKDKDFDEPYRGAPPTLKLRDSLYFGIEPLVHVNGLETLVESCFATPTSKIDEILKYYLIQDGCVSDDSVKQYTSKDHLAKHFQVPVFKFVGKDNKEVFLHCRILVCGALDESSRCAQGCRRRVRRSSGTEEQDESGNLANHLLTGGPIRIDFDD", "length": 543, "header": "tr|A0A8V0ZQ18-1|A0A8V0ZQ18_CHICK Isoform 1 of Oncoprotein-induced transcript 3 protein OS=Gallus gallus OX=9031 GN=OIT3 PE=1 SV=1 CANONICAL=A0A8V0ZQ18-1" }, "locus": { "chromosome": "6", "start_pos": 11971117, "end_pos": 11951752, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051689.1", "url": "https://www.ensembl.org/id/ENSGALT00010051689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030828.1", "url": "https://www.ensembl.org/id/ENSGALP00010030828.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ18" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ18" } ], "pmid": "" }, { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ18" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ18", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { 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"isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRN7-1", "uniprot_ac": "A0A8V0ZRN7", "uniprot_id": "A0A8V0ZRN7_CHICK", "mass": { "chemical_mass": 223284.0, "monoisotopic_mass": 223284.0 }, "refseq": { "ac": "XP_422062", "name": "zinc finger protein 142 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422062" }, "gene_names": [ { "name": "ZNF142", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7" } ] }, { "name": "ZNF142", "type": "synonym", "evidence": [ { "id": "XP_422062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422062" } ] } ], "protein_names": [ { "name": "Zinc finger protein 142", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 142 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_422062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422062" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422062.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422062" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZJA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJA0#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A8V0ZKV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV1#function" }, { "database": "UniProtKB", "id": "A0A8V0ZRN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF142", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7", "locus": { "chromosome": "7", "start_pos": 22107175, "end_pos": 22096753, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021626", "url": "https://www.ensembl.org/id/ENSGALG00010021626" } ] } } ], "crossref": [ { "id": "424213", "url": "https://www.ncbi.nlm.nih.gov/gene/424213", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ADCEYST", "url": "https://omabrowser.org/oma/group/ADCEYST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZJA0", "url": "https://www.orthodb.org/?gene=A0A8V0ZJA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZKV1", "url": "https://www.orthodb.org/?gene=A0A8V0ZKV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRN7", "url": "https://www.orthodb.org/?gene=A0A8V0ZRN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27528", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27528", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422062", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJA0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZJA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZJA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAEVAAPQAAGEEMEALCSELLLPSPGAVGAAGAVGSPTATAGAAPLPVSQELVLAEASSPGEGAAAEGSNVEIFIEAVAGNVTLSNAANGTEVLVKVVELYFCERCGQSFPEASLLSQHECLLLPPPEHLQLPEVLPAPTSKGQNESEGSEPPLVGVSEGSALQCLLCPICQEAFAQPGELKEHFKTHRGPQGALPCPEKGCCFATEDRKQLRSHLRLLHGASPVSCTYRACPLLFPSRPAMEQHHRTHFPFHCGHCDFVTANAKLFWQHRKGHVAETSVMSSIPSSAPLKQLCILPSEGQKEAENCHADWEATSEETRPANPSGIGEGSLEELKASAGEEDSESDEDDSLEEDGESPCEGEAKENRKVADKAKVTWAQHFKGDVAEGSEYVYKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCHKYFTSKSKLKIHMMRETGEKVHRCPLCHYSSVEKNALNRHMASMHEDISNFYSDVYSCPVCKEKFRLSQALKEHLKTHKAEPKRLSCFQGGCDYCVEDRKEFVRHLKDSHGIKAVECKYHACSLLFGTAEAMEAHRKTHYAFHCQQCDFICSNKHVFRKHKKQGHPGSEQLQCSFCPYATFNPVEYHDHVGKMHANEKIHKCTECAFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSSDKNFMCTECGYITKWKHYLNVHMRKHTGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLICEVCGFACKRKYELQKHMQAKHSQNYQVPIFQCQYCAYQTKYKQALLNHENCKHTKQKEFRCALCSYCTFSNTSLFFHKRKIHGYVPGDKDWLENYASKELEISSSESVFGYELGAALRVDASSPFSSKEQWAKVKPSQPESQGEEGCQQAFMVPLLGQDAAPPEGSSKAQTAVGKGEQSCTVDDSMQSDTAAGSAELITSEDVAESCTLHLETVNVSSDPILEHLTGDACMAQPESMEMLSCKEPPAAYEMLGSQDDLGLEDNDNELEDIPDYKEEEADVRKDEMLRLEDSAAAGASQENDTIGEATGHLERSCSDHSKLDAGPEMRETSQREPPEAWLSVLKTAEQSHPSIPVDAATSTDDTRNSSESVLKALRKQDKEQAETLVLEGRVQMLVVQSESQIFKCEKCSYITRKEKSMSLHSKASCQSHRTPLVCCECGASFKQQRGLNTHLLKKCPVLLKKNKVLKPAVVEAAGSHRPTGQLGDNGTETAESDRGGMEEPGHPESPWEAKMMPDKMQESDGPFAGEQVSGCPSPVKSLSGDSAEVAEEPSQQGDGAETSGMERPLQAGKPSEKYRLEGGKLHCNACSFVCSRVSTITSHVEDGCRSLEQFWCSLCPEAFRSQRALKNHCAEKHLLHPEEDRPHGTQLPGGDPASAEMGQPADPVLDAAPLKAALPKQRRFSCPTCPFTCHQERAMKTHKKRGCVALGEFRCASCPFTSKAAKALRLHRKLHRKHYSKRPQLQCRQCEFTCKQARCLRQHVRIKHEGVKPHKCLYCEFSTTRRYRLEAHQSLHTGVGRIACGICSQTFGTNSKLRIHRLRVHEKTPTHFCPLCDYSSYLQNDITRHVNSCHRGELNFGCSRCEARFSSETALKQHVLRRHEEKVSYGCPQCGFVCHSEATLKCHVQKQHPHLECGTCKESFPSRDALEEHKKQHFSHRCELCSFAAKERQQLVRHYVESHEPATPQDKPLRCPFCDFACRHQLVFDQHMKGHGGTCIYKCSDCEYTTKNRQKITWHIRIHTGEKPYKCHLCKYTCADPSRLKYHMRIHKEERKYLCPDCGYKCKWVNQLKYHMTKHTGLKPYRCDECEYRTNRADALRVHQETRHRDARSFICEQCGKAFKTRFLLKTHLKKHSEEKPYVCNACGRAFRWAAGLRHHYLTHTNEHPFFCRYCPYKAKQKFQVIKHIQRHHPERGAGDPSQGVGKDPSTPIVRLHAVQRESPAMGPPAPQQEGECLPEKESISQ", "length": 1988, "header": "tr|A0A8V0ZRN7-1|A0A8V0ZRN7_CHICK Isoform 1 of Zinc finger protein 142 OS=Gallus gallus OX=9031 GN=ZNF142 PE=3 SV=1 CANONICAL=A0A8V0ZRN7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7/entry#A0A8V0ZJA0-1", "sequence": { "sequence": "MRWAGPAEVLVKVVELYFCERCGQSFPEASLLSQHECLLLPPPEHLQLPEVLPAPTSKGQNESEGSEPPLVGVSEGSALQCLLCPICQEAFAQPGELKEHFKTHRGPQGALPCPEKGCCFATEDRKQLRSHLRLLHGASPVSCTYRACPLLFPSRPAMEQHHRTHFPFHCGHCDFVTANAKLFWQHRKGHVAETSVMSSIPSSAPLKQLCILPSEGQKEAENCHADWEATSEETRPANPSGIGEGSLEELKASAGEEDSESDEDDSLEEDGESPCEGEAKENRKVADKAKVTWAQHFKGDVAEGSEYVYKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCHKYFTSKSKLKIHMMRETGEKVHRCPLCHYSSVEKNALNRHMASMHEDISNFYSDVYSCPVCKEKFRLSQALKEHLKTHKAEPKRLSCFQGGCDYCVEDRKEFVRHLKDSHGIKAVECKYHACSLLFGTAEAMEAHRKTHYAFHCQQCDFICSNKHVFRKHKKQGHPGSEQLQCSFCPYATFNPVEYHDHVGKMHANEKIHKCTECAFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSSDKNFMCTECGYITKWKHYLNVHMRKHTGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLICEVCGFACKRKYELQKHMQAKHSQNYQVPIFQCQYCAYQTKYKQALLNHENCKHTKQKEFRCALCSYCTFSNTSLFFHKRKIHGYVPGDKDWLENYASKELEISSSESVFGYELGAALRVDASSPFSSKEQWAKVKPSQPESQGEEGCQQAFMVPLLGQDAAPPEGSSKAQTAVGKGEQSCTVDDSMQSDTAAGSAELITSEDVAESCTLHLETVNVSSDPILEHLTGDACMAQPESMEMLSCKEPPAAYEMLGSQDDLGLEDNDNELEDIPDYKEEEADVRKDEMLRLEDSAAAGASQENDTIGEATGHLERSCSDHSKLDAGPEMRETSQREPPEAWLSVLKTAEQSHPSIPVDAATSTDDTRNSSESVLKALRKQDKEQAETLVLEGRVQMLVVQSESQIFKCEKCSYITRKEKSMSLHSKASCQSHRTPLVCCECGASFKQQRGLNTHLLKKCPVLLKKNKVLKPAVVEAAGSHRPTGQLGDNGTETAESDRGGMEEPGHPESPWEAKMMPDKMQESDGPFAGEQVSGCPSPVKSLSGDSAEVAEEPSQQGDGAETSGMERPLQAGKPSEKYRLEGGKLHCNACSFVCSRVSTITSHVEDGCRSLEQFWCSLCPEAFRSQRALKNHCAEKHLLHPEEDRPHGTQLPGGDPASAEMGQPADPVLDAAPLKAALPKQRRFSCPTCPFTCHQERAMKTHKKRGCVALGEFRCASCPFTSKAAKALRLHRKLHRKHYSKRPQLQCRQCEFTCKQARCLRQHVRIKHEGVKPHKCLYCEFSTTRRYRLEAHQSLHTGVGRIACGICSQTFGTNSKLRIHRLRVHEKTPTHFCPLCDYSSYLQNDITRHVNSCHRGELNFGCSRCEARFSSETALKQHVLRRHEEKVSYGCPQCGFVCHSEATLKCHVQKQHPHLECGTCKESFPSRDALEEHKKQHFSHRCELCSFAAKERQQLVRHYVESHEPATPQDKPLRCPFCDFACRHQLVFDQHMKGHGGTCIYKCSDCEYTTKNRQKITWHIRIHTGEKPYKCHLCKYTCADPSRLKYHMRIHKEERKYLCPDCGYKCKWVNQLKYHMTKHTGLKPYRCDECEYRTNRADALRVHQETRHRDARSFICEQCGKAFKTRFLLKTHLKKHSEEKPYVCNACGRAFRWAAGLRHHYLTHTNEHPFFCRYCPYKAKQKFQVIKHIQRHHPERGAGDPSQGVGKDPSTPIVRLHAVQRESPAMGPPAPQQEGECLPEKESISQ", "length": 1902, "header": "tr|A0A8V0ZJA0-1|A0A8V0ZRN7_CHICK Computationally mapped isoform of Zinc finger protein 142 OS=Gallus gallus OX=9031 GN=ZNF142 PE=3 SV=1 CANONICAL=A0A8V0ZRN7-1" }, "locus": { "chromosome": "7", "start_pos": 22106171, "end_pos": 22097003, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052529.1", "url": "https://www.ensembl.org/id/ENSGALT00010052529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031436.1", "url": "https://www.ensembl.org/id/ENSGALP00010031436.1" } ] } }, { "isoform_ac": "A0A8V0ZKV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7/entry#A0A8V0ZKV1-1", "sequence": { "sequence": "MRPTAPRCWSKWWSCISARDVARASRRLPCCPSTSACYCHHQSTCSYLKCCQHPPGALPCPEKGCCFATEDRKQLRSHLRLLHGASPVSCTYRACPLLFPSRPAMEQHHRTHFPFHCGHCDFVTANAKLFWQHRKGHVAETSVMSSIPSSAPLKQLCILPSEGQKEAENCHADWEATSEETRPANPSGIGEGSLEELKASAGEEDSESDEDDSLEEDGESPCEGEAKENRKVADKAKVTWAQHFKGDVAEGSEYVYKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCHKYFTSKSKLKIHMMRETGEKVHRCPLCHYSSVEKNALNRHMASMHEDISNFYSDVYSCPVCKEKFRLSQALKEHLKTHKAEPKRLSCFQGGCDYCVEDRKEFVRHLKDSHGIKAVECKYHACSLLFGTAEAMEAHRKTHYAFHCQQCDFICSNKHVFRKHKKQGHPGSEQLQCSFCPYATFNPVEYHDHVGKMHANEKIHKCTECAFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSSDKNFMCTECGYITKWKHYLNVHMRKHTGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLICEVCGFACKRKYELQKHMQAKHSQNYQVPIFQCQYCAYQTKYKQALLNHENCKHTKQKEFRCALCSYCTFSNTSLFFHKRKIHGYVPGDKDWLENYASKELEISSSESVFGYELGAALRVDASSPFSSKEQWAKVKPSQPESQGEEGCQQAFMVPLLGQDAAPPEGSSKAQTAVGKGEQSCTVDDSMQSDTAAGSAELITSEDVAESCTLHLETVNVSSDPILEHLTGDACMAQPESMEMLSCKEPPAAYEMLGSQDDLGLEDNDNELEDIPDYKEEEADVRKDEMLRLEDSAAAGASQENDTIGEATGHLERSCSDHSKLDAGPEMRETSQREPPEAWLSVLKTAEQSHPSIPVDAATSTDDTRNSSESVLKALRKQDKEQAETLVLEGRVQMLVVQSESQIFKCEKCSYITRKEKSMSLHSKASCQSHRTPLVCCECGASFKQQRGLNTHLLKKCPVLLKKNKVLKPAVVEAAGSHRPTGQLGDNGTETAESDRGGMEEPGHPESPWEAKMMPDKMQESDGPFAGEQVSGCPSPVKSLSGDSAEVAEEPSQQGDGAETSGMERPLQAGKPSEKYRLEGGKLHCNACSFVCSRVSTITSHVEDGCRSLEQFWCSLCPEAFRSQRALKNHCAEKHLLHPEEDRPHGTQLPGGDPASAEMGQPADPVLDAAPLKAALPKQRRFSCPTCPFTCHQERAMKTHKKRGCVALGEFRCASCPFTSKAAKALRLHRKLHRKHYSKRPQLQCRQCEFTCKQARCLRQHVRIKHEGVKPHKCLYCEFSTTRRYRLEAHQSLHTGVGRIACGICSQTFGTNSKLRIHRLRVHEKTPTHFCPLCDYSSYLQNDITRHVNSCHRGELNFGCSRCEARFSSETALKQHVLRRHEEKVSYGCPQCGFVCHSEATLKCHVQKQHPHLECGTCKESFPSRDALEEHKKQHFSHRCELCSFAAKERQQLVRHYVESHEPATPQDKPLRCPFCDFACRHQLVFDQHMKGHGGTCIYKCSDCEYTTKNRQKITWHIRIHTGEKPYKCHLCKYTCADPSRLKYHMRIHKEERKYLCPDCGYKCKWVNQLKYHMTKHTGLKPYRCDECEYRTNRADALRVHQETRHRDARSFICEQCGKAFKTRFLLKTHLKKHSEEKPYVCNACGRAFRWAAGLRHHYLTHTNEHPFFCRYCPYKAKQKFQVIKHIQRHHPERGAGDPSQGVGKDPSTPIVRLHAVQRESPAMGPPAPQQEGECLPEKESISQ", "length": 1849, "header": "tr|A0A8V0ZKV1-1|A0A8V0ZRN7_CHICK Computationally mapped isoform of Zinc finger protein 142 OS=Gallus gallus OX=9031 GN=ZNF142 PE=3 SV=1 CANONICAL=A0A8V0ZRN7-1" }, "locus": { "chromosome": "7", "start_pos": 22106171, "end_pos": 22097567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052521.1", "url": "https://www.ensembl.org/id/ENSGALT00010052521.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031428.1", "url": "https://www.ensembl.org/id/ENSGALP00010031428.1" } ] } }, { "isoform_ac": "A0A8V0ZRN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7/entry#A0A8V0ZRN7-1", "sequence": { "sequence": "MSAEVAAPQAAGEEMEALCSELLLPSPGAVGAAGAVGSPTATAGAAPLPVSQELVLAEASSPGEGAAAEGSNVEIFIEAVAGNVTLSNAANGTEVLVKVVELYFCERCGQSFPEASLLSQHECLLLPPPEHLQLPEVLPAPTSKGQNESEGSEPPLVGVSEGSALQCLLCPICQEAFAQPGELKEHFKTHRGPQGALPCPEKGCCFATEDRKQLRSHLRLLHGASPVSCTYRACPLLFPSRPAMEQHHRTHFPFHCGHCDFVTANAKLFWQHRKGHVAETSVMSSIPSSAPLKQLCILPSEGQKEAENCHADWEATSEETRPANPSGIGEGSLEELKASAGEEDSESDEDDSLEEDGESPCEGEAKENRKVADKAKVTWAQHFKGDVAEGSEYVYKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCHKYFTSKSKLKIHMMRETGEKVHRCPLCHYSSVEKNALNRHMASMHEDISNFYSDVYSCPVCKEKFRLSQALKEHLKTHKAEPKRLSCFQGGCDYCVEDRKEFVRHLKDSHGIKAVECKYHACSLLFGTAEAMEAHRKTHYAFHCQQCDFICSNKHVFRKHKKQGHPGSEQLQCSFCPYATFNPVEYHDHVGKMHANEKIHKCTECAFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSSDKNFMCTECGYITKWKHYLNVHMRKHTGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLICEVCGFACKRKYELQKHMQAKHSQNYQVPIFQCQYCAYQTKYKQALLNHENCKHTKQKEFRCALCSYCTFSNTSLFFHKRKIHGYVPGDKDWLENYASKELEISSSESVFGYELGAALRVDASSPFSSKEQWAKVKPSQPESQGEEGCQQAFMVPLLGQDAAPPEGSSKAQTAVGKGEQSCTVDDSMQSDTAAGSAELITSEDVAESCTLHLETVNVSSDPILEHLTGDACMAQPESMEMLSCKEPPAAYEMLGSQDDLGLEDNDNELEDIPDYKEEEADVRKDEMLRLEDSAAAGASQENDTIGEATGHLERSCSDHSKLDAGPEMRETSQREPPEAWLSVLKTAEQSHPSIPVDAATSTDDTRNSSESVLKALRKQDKEQAETLVLEGRVQMLVVQSESQIFKCEKCSYITRKEKSMSLHSKASCQSHRTPLVCCECGASFKQQRGLNTHLLKKCPVLLKKNKVLKPAVVEAAGSHRPTGQLGDNGTETAESDRGGMEEPGHPESPWEAKMMPDKMQESDGPFAGEQVSGCPSPVKSLSGDSAEVAEEPSQQGDGAETSGMERPLQAGKPSEKYRLEGGKLHCNACSFVCSRVSTITSHVEDGCRSLEQFWCSLCPEAFRSQRALKNHCAEKHLLHPEEDRPHGTQLPGGDPASAEMGQPADPVLDAAPLKAALPKQRRFSCPTCPFTCHQERAMKTHKKRGCVALGEFRCASCPFTSKAAKALRLHRKLHRKHYSKRPQLQCRQCEFTCKQARCLRQHVRIKHEGVKPHKCLYCEFSTTRRYRLEAHQSLHTGVGRIACGICSQTFGTNSKLRIHRLRVHEKTPTHFCPLCDYSSYLQNDITRHVNSCHRGELNFGCSRCEARFSSETALKQHVLRRHEEKVSYGCPQCGFVCHSEATLKCHVQKQHPHLECGTCKESFPSRDALEEHKKQHFSHRCELCSFAAKERQQLVRHYVESHEPATPQDKPLRCPFCDFACRHQLVFDQHMKGHGGTCIYKCSDCEYTTKNRQKITWHIRIHTGEKPYKCHLCKYTCADPSRLKYHMRIHKEERKYLCPDCGYKCKWVNQLKYHMTKHTGLKPYRCDECEYRTNRADALRVHQETRHRDARSFICEQCGKAFKTRFLLKTHLKKHSEEKPYVCNACGRAFRWAAGLRHHYLTHTNEHPFFCRYCPYKAKQKFQVIKHIQRHHPERGAGDPSQGVGKDPSTPIVRLHAVQRESPAMGPPAPQQEGECLPEKESISQ", "length": 1988, "header": "tr|A0A8V0ZRN7-1|A0A8V0ZRN7_CHICK Isoform 1 of Zinc finger protein 142 OS=Gallus gallus OX=9031 GN=ZNF142 PE=3 SV=1 CANONICAL=A0A8V0ZRN7-1" }, "locus": { "chromosome": "7", "start_pos": 22106171, "end_pos": 22097305, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052533.1", "url": "https://www.ensembl.org/id/ENSGALT00010052533.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031440.1", "url": "https://www.ensembl.org/id/ENSGALP00010031440.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JVD5-1", "protein_name": "Zinc finger protein 142", "gene_name": "Zfp142", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTDPALASQLTNGTGEMDGLCSELLLIPPPLSNRGILGPVQNTCASGEPAPLPADPGCLLVEATATEEGPGNMEIIVEAVAGTLSPGAPGETSGVLVKVVEVYFCERCEQSFAEPTLLSLHQCTETHIQAVQDLSSPPCSVELPPSNLTLHGPLQDPSLPDSPLLCPVCRQEFVQPQALKSHFKIHRVTPNMFSCPESGCVFSAEDRKGLQHHLRQTHKAVPVPCSFRGCSLLFGSQQGMELHRQAHYPFHCSHCSFMGSNVKLFRQHQRSHGASTRGELSAVQGLPSQELLPAAKLPPGDREPSEEAGAPLPGQESAEEEDVEEEENVAQKDSQKVLDKSQGAQQLEGHVASGTESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHRCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLHCFQEGCLYVAPDRKAFLKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCSECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLSVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCRYCSYQSRHKQALLSHENCKHTHLREFHCALCDYRTFSNTTLFFHKRKVHGYMPGDQVWQFCNASQELEGARQCLAPPSDSGPSSQLSAQPEKEDHEHEIGASSIVDQALPETNEEASTKRQDGIEAPQEDDQVGSPSLGEVEEGGCTLHLEALRVELEPEAEPPPLEELTETAAVEFRPLEPSGPLRTDRPGGLAEPQLPDFDSAGTPAFDSAGTPAFDSAGTSALVAEEEPLLEKLASEPPRNPLISEEAPNTFKATLTAETVPLPQVPESESLLKAMRRQDKEQAEALVLEGRVQMVVIQGEGRAFRCPHCPFITRREKALTLHSKSGCQGRREPLLCPECGASFKQQRGLSTHMLKKCPVLLRKNKALALPKPVSPTLHPELPSSQASQDAESRKPPPSPSKVELSISKDASSELPGEPGVEEHLPTPSDFPTSPPGNSLPTGTSEKFHFEQGKFHCNSCTFLCSRLSSITSHVTEGCRGAHSQGRKRGRPQTHAVVLPLNNGDSTLLNTGSTDSSPGDRDTAVVQKQKGTLYSCPTCPFSCQQERTLKTHQTQGCPLEPGDLHCGLCPFTAPAPAALRLHQKRRHPTASPASGPRPLLQCGDCGFTCKQSRCLQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGVGRIPCSSCPQTFGTNSKLRLHQLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPSFSCSQCEAQFSSETALKQHALRRHPEPTPSSGCPVDVTEGPLHCSHCGLLCPSPASLRGHTRKQHPRLECGACQESFPSRPALDEHRRQHHFSHRCQLCSFAARERVGLVKHYLEQHEETSTAPSDGDAGQPSLCCPFCDFACRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYRCHLCSYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHRETRHKEARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCSYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPTTPTVHLHDVKLEDPSPPAPPAPPTGPEG", "length": 1859 }, "evidence": [ { "id": "A0A8V0ZRN7", "url": "https://omabrowser.org/oma/group/A0A8V0ZRN7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BNL0-1", "protein_name": "Zinc finger protein 142", "gene_name": "ZNF142", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMTDTVLDSQPANSTGEMDGLCPELLLIPPPLSNHGILEPVHSPCPGNPPPLPPDPGCLLVEATATEEDTGNMEIIVEAVAGNLSPGAPGETPGVLVKVMEVYFCERCEQSFAEPTLLALHQCTETLMQPVQGLPTPPCSVELPPSNLTLPSPLQGQSPPDSPLPCPVCRQEFAQPQALKSHFKMHWGTPDTFSCPESGCVFSTEDRKELHQHLRLTHRALPVPCSFRGCPLLFGSQQGMELHRQTHYPFHCNRCSFVGSNVKLFRQHQRSHGAGTQQELSAVMGLPSQELLPAPKVPPGTGEPSEETGAPSPGQESVEEEEEERGSQKSSQKALELEGTVASGTESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGQKAHRCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTVAAAAEPQPLCCFQEGCGHTAPDRKAFVKHLKETHGVRAVECRHHSCPMLFATVEAMEAHHKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECSFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSSTKDYMCTECGYVTKWKHYLSVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPGTPVPLYPCRYCSYQSRHKQALLSHENCKHTRLREFRCALCDYRTFSNTTLFFHKRKAHGYVPGDQVWQLRGASQEPEGARQCPTPSPDSEPASQPSAQPEGPDHDPGAVIDPTLIQALPETSEEGSAGKQDSSEVPQGDDLVGSPSPAEVDEGSCTLHLEALGVELGPVADPPLEEVTETAPVEFRPLDPPGPLSLEGPEGTLTDLSTFEGAGTSDLGAEEPILEKSGSQPPTNPPSSEEPLDGWVGTFKATTATETAPLPQLPESESLLKALRRQDKEQAEALVLEGRVQMVVIQAEGRAFRCPHCPFITRREKALSLHSRTGCQGRREPLLCPECGASFKQQRGLSTHLLKKCPVLLRKNKGLPRPDSPITLQPLPPSTAASEDAEGGKPPAAPLGEEIVLPRDAPEPSREPEKIGEPLALLSGSTVPPVGDSLPSEAPEKFHFEQGKFHCNSCAFLCSRLSSITSHVAEGCRGGRGWGGKRGAVQTQPALSPLSSGDSAPLSGGSTERSPGDGELALLPKQKAARFSCPTCPFSCQQERALRTHQTRGCPLEPSGELRCGLCPFTAPAPAALKLHQKRRHPAATPARGPRPPLQCGDCGFTCKQSRCLQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGVGRIRCNSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACPQCEAQFSSETALKQHALRRHPEPTLPTPGSPAEATEGPLHCTRCGLLCASPASLRGHTRKQHPRLECGACQEAFPSRPALDEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQHETSEAAAASAGEGDSGQALLRCPFCDFACRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYRCHLCPYACADPSRLKYHMRIHKEERKYLCPDCGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCSYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPTTPTVHLHDVQLEDPGPPAPAAPPTGPEG", "length": 1838 }, "evidence": [ { "id": "A0A8V0ZRN7", "url": "https://omabrowser.org/oma/group/A0A8V0ZRN7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E9QCQ3-1", "protein_name": "Zinc finger protein 142", "gene_name": "znf142", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLQESGCAAEQLEHLKNNATTDTPEVLSQFKGTDMPVQSSSKKNRKKCKAKEKGKISITGSQGKSPSKVGHVAEGTEHIFRTHICSECRRCFKTRSHLIEHTRIHFPDPTLQCPTCKHYFTSKSKLRVHMLREMGQKLHQCHLCEYKAVERNSLRRHLASVHGHQEDDASKGEPFKCPTCQKTFGQSQALKSHMKSHNKTQHGQPLLCFHKGCSYQCTEKKQLYKHALDAHKIEATECRHHACGAFFGSLEDMEKHFRTHQAYHCPHCDFSCSNKSSFQQHKRQGHPGKQDLNCSFCPFSTLNPVEFEQHVGHFHASEKTHRCSQCGFVTAHKRVLKRHMLMHTGEKPHKCTLCEFRCRDETYLSKHMLTHSNDKQHMCSECGYVTKWKHYLSVHMRKHAGDLRYKCNQCSYRCHRMDQLNSHRLRHQEKSLICEVCAYSCKRKTELRSHMQLKHSTNADAQPPVYQCKFCPYTTKYRQALLSHENCRHTRTRMFRCALCRYTTFSNTGLFLHKKKSHGYVPGDVIWLKNYAEKEKEQSSVDLTDNFFSKTAAPQTSNLEYREETSNKTIGDSQDVSLNDNEDEAIRAPIAQTEKMTERHPNDEECSTLLYSSQTSMESTQMIPAETANIHNTAFNVHIGSNAGSHTLHSIHQNIPEPSAENEDDDDDDDGVYCRAQSDSEDLTQLTGFELHQDSFVQPSTSETCLQVLRKQDKDQAKALVLEGRVQMLVVRTQDNMYQCSRCSYVTRKQAALVRHSKTSCQVMKTGLRCQDCGMHFKQQRSLHTHRLRKCRSLPSGGKKSDLPNAIGKSERCVGHSRSTNLISGTPTIQIESLEVTDLRLKGSAEPQGSLSPIITDVIDETDSLPSTSEEGQATIRTINKLAKVDVSVNDEVSGYTEEGGRFTCRTCPFSSVRKVTINRHCATCSGSAPKIYLAEMAGQFEQEDHFNDSDQEDEDVDGANDSEGDSAVDERSPSSIPRFSCPNCPFLCHQKRALASHEVKGCLKQGEIQCPHCSFVAKSDKSLSHHILSHKKDKKATKGKRSGNLQCDLCSFTCKQERCLMQHVAVKHEGVRPHQCRFCSFSTVRRYRLEAHESMHTGVGRHSCELCGQTFGTTSRLRLHHQRIHDKQATHFCSVCDYRAYNLNDINRHNLSCHTGELRYHCSQCDARFSSDGALKQHCHRVHSDANTLPCTQCSFTCRGQAALKAHMQSDHSEKTNDPQDNPEKRSKKSITHKCTVCSFNTNKRLLLVQHMLDEHEDGPAEEKTLKCDVCGFSCTHQMVFDQHIRSHGGTCLFKCTECEFSTRNKQKITWHIRIHTGEKPYRCEKCNYACADPSRLKYHMRIHMDERKYLCPECGYKCKWVNQLKYHMTKHTGAKPYACEDCEYRTNRADALRIHRETRHRDVRSFICEKCGKAFKTRFLLKTHQRKHSEARPYVCSVCQKAFRWPAGLRHHYLSHTNQLPFYCLHCPYRAKQKFQVVKHLHRHHPDLPVQNGVGKNQEASSAGTQKTWNREGEGQEDGQTAVQHMQTAEDM", "length": 1535 }, "evidence": [ { "id": "A0A8V0ZRN7", "url": "https://omabrowser.org/oma/group/A0A8V0ZRN7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P52746-1", "protein_name": "Zinc finger protein 142", "gene_name": "ZNF142", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDPLLDSQPASSTGEMDGLCPELLLIPPPLSNRGILGPVQSPCPSRDPAPIPTEPGCLLVEATATEEGPGNMEIIVETVAGTLTPGAPGETPAPKLPPGEREPSQEAGTPLPGQETAEEENVEKEEKSDTQKDSQKAVDKGQGAQRLEGDVVSGTESLFKTHMCPECKRCFKKRTHLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVPGDQAWQLRYASQEPEGAMQGPTPPPDSEPSNQLSARPEGPGHEPGTVVDPSLDQALPEMSEEVNTGRQEGSEAPHGGDLGGSPSPAEVEEGSCTLHLEALGVELESVTEPPLEEVTETAPMEFRPLGLEGPDGLEGPELSSFEGIGTSDLSAEENPLLEKPVSEPSTNPPSLEEAPNNWVGTFKTTPPAETAPLPPLPESESLLKALRRQDKEQAEALVLEGRVQMVVIQGEGRAFRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTHLLKKCPVLLRKNKGLPRPDSPIPLQPVLPGTQASEDTESGKPPPASQEAELLLPKDAPLELPREPEETEEPLATVSGSPVPPAGNSLPTEAPKKHCFDPVPPAGNSSPTEAPKKHHLDPVPPAGNSSPTEALKKHRFEQGKFHCNSCPFLCSRLSSITSHVAEGCRGGRGGGGKRGTPQTQPDVSPLSNGDSAPPKNGSTESSSGDGDTVLVQKQKGARFSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQGVGKDPTTPTVHLHDVQLEDPSPPAPAAPHTGPEG", "length": 1687 }, "evidence": [ { "id": "A0A8V0ZRN7", "url": "https://omabrowser.org/oma/group/A0A8V0ZRN7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": 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"structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN7" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 103, "end_pos": 122, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1045, "end_pos": 1047 }, { "start_pos": 1110, "end_pos": 1112 }, { "start_pos": 1231, "end_pos": 1233 }, { "start_pos": 147, "end_pos": 149 }, { 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"recommended", "evidence": [ { "id": "A0A8V0ZQ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83/entry#names_and_taxonomy" } ] }, { "name": "Deubiquitinating enzyme 24", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin thioesterase 24", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin-specific-processing protease 24", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 24 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015146673", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146673" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015146673.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146673" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USP24", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83", "locus": { "chromosome": "8", "start_pos": 24973211, "end_pos": 25031262, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022813", "url": "https://www.ensembl.org/id/ENSGALG00010022813" } ] } } ], "crossref": [ { "id": "cd02659", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02659", "database": "CDD", "categories": [ "Protein 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"MESEEEQHMTTLLCMGFSDAAAIRKALRLAKNDINEAVALLTNERPGLHYGGYEPMESGQGPPPGHGSPAGGQGSRDGDGGGGGGSGGFDPPPAYHEVVETEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLIASTYLARLGLSDSDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLVDLVAERVKQDPIPVGLLGVLTMAFNPDNEYHFKNRMKVCQRNWAEVFGEGNMHAVSPISTFQKEPHGWLVDLVNRFAELGGFSAIQSKLNSEDIELGAISALVQPFGVCAEYLNSSVVQPMLDPVIHKMIKYVQNVEEKDLKDKRLVSIPELLSGIKLLCMRFQPDLVTAVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTVSKSVKNAIDTDRLLNWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWRIQSGQSSTVIENIHTIIAAAAVKFSSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARVETTTGKVLEVLWELAHLPTLPCSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRKMKPPRKAMSSSNNESSQHNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLISCHRLAASVAGPGGLVGATLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFSLFKTFFENVNLCDHRLKRQGTQLSVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLTPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDLYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTIEAHSNETVGSIRWKIAKMLNSPVDNIQIFANDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSNSSSVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSESSSQSSKSPSLSSKHQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDEMARNCAKSFCENFLRAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDFIKDGVEALSSRPFRNVSRQASRQMSICGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVNDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKENNTLFPAGIRNRLSSSGSNCSSGSEGEPTALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLGSFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSTHPDVQKPNQFLLSVILGAQLPLWSPTSIMRGINQRLLSQCTEYFDLRCQLLDDLTSSEMEQLKISPAAMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMVGSSLIKPLLDDFLFRASRIILNSHSPSGSAAISQQDFHPKCSTADSRLAAYEVLVMLADSSPSNLQLITKELLSMHHQCDPALTKEFDYLPPVDSRSISGFVGLKNGGATCYMNAVFQQLYMQPGLPEALLSIDDDTDNPDDNVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKIGRDQIFKNTFQGIFSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKVLPNLLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGDNGRNVDQGGGGSPRKKVAPTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVVEEFELTDETLEYECFGGEYRPKVYDQSNPYPDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNSDRLSILTKLVRKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKVKHPYYPCMAKVSLQLAVQFLFQTYLRTKKKLRADTEEWIATIDALLSKSIDACQWLVEYFVGPEGRELVKTFLLECSVREVRVAVATILEKTLDSALFYQEKLKSLHQLLEVLLALLDKDVPENCKNCAQYFLLFNNFVQKQGIRASSLLLRHSALRHMINFLLGPNRQSNQNRRWSSAQAREFGYLHNTVALLVLHSDVSSQRNVAPGLFKQRPPLSITTSGPLLTLHEEVEALLFLSEGKPYLIEVMYALRELTGSLSVLIEMVVYCCFCNEHFSFTVLHFIKTQLETAPPHELKNIFQLLHEILVIEDPLQVERIKFAFETENGLIALMHHSNHVDSSRCYQCVKFLVTLAQKCPTAKDYFKENSHHWSWAVQWLQKKMSEHYWAPQSNVSNETSTAKTFQRTISAQDTLAYATALLNEKDQSGSSNGSESSPANENGDRHLQQGSESPMMIGETKNDLDDVDP", "length": 2612, "header": "tr|A0A8V0ZQ83-1|A0A8V0ZQ83_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 24 OS=Gallus gallus OX=9031 GN=USP24 PE=1 SV=1 CANONICAL=A0A8V0ZQ83-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZJV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83/entry#A0A8V0ZJV2-1", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDAAAIRKALRLAKNDINEAVALLTNERPGLHYGGYEPMESGQGPPPGHGSPAGGQGSRDGDGGGGGGSGGFDPPPAYHEVVETEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLIASTYLARLGLSDSDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLVDLVAERVKQDPIPVGLLGVLTMAFNPDNEYHFKNRMKVCQRNWAEVFGEGNMHAVSPISTFQKEPHGWLVDLVNRFAELGGFSAIQSKLNSEDIELGAISALVQPFGVCAEYLNSSVVQPMLDPVIHKMIKYVQNVEEKDLKDKRLVSIPELLSGIKLLCMRFQPDLVTAVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTVSKSVKNAIDTDRLLNWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWRIQSGQSSTVIENIHTIIAAAAVKFSSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARVETTTGKVLEVLWELAHLPTLPCSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRSSQHNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLISCHRLAASVAGPGGLVGATLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFSLFKTFFENVNLCDHRLKRQGTQLSVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLTPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDLYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTIEAHSNETVGSIRWKIAKMLNSPVDNIQIFANDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSNSSSVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSESSSQSSKSPSLSSKHQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDEMARNCAKSFCENFLRAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDFIKDGVEALSSRPFRNVSRQASRQMSICGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVNDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKENNTLFPAGIRNRLSSSGSNCSSGSEGEPTALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLGSFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSTHPDVQKPNQFLLSVILGAQLPLWSPTSIMRGINQRLLSQCTEYFDLRCQLLDDLTSSEMEQLKISPAAMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMVGSSLIKPLLDDFLFRASRIILNSHSPSGSAAISQQDFHPKCSTADSRLAAYEVLVMLADSSPSNLQLITKELLSMHHQCDPALTKEFDYLPPVDSRSISGFVGLKNGGATCYMNAVFQQLYMQPGLPEALLSIDDDTDNPDDNVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKIGRDQIFKNTFQGIFSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKVLPNLLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGDNGRNVDQGGGGSPRKKVAPTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVVEEFELTDETLEYECFGGEYRPKVYDQSNPYPDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNSDRLSILTKLVRKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKVKHPYYPCMAKVSLQLAVQFLFQTYLRTKKKLRADTEEWIATIDALLSKSIDACQWLVEYFVGPEGRELVKTFLLECSVREVRVAVATILEKTLDSALFYQEKLKSLHQLLEVLLALLDKDVPENCKNCAQYFLLFNNFVQKQGIRASSLLLRHSALRHMINFLLGPNRQSNQNRRWSSAQAREFGYLHNTVALLVLHSDVSSQRNVAPGLFKQRPPLSITTSGPLLTLHEEVEALLFLSEGKPYLIEVMYALRELTGSLSVLIEMVVYCCFCNEHFSFTVLHFIKTQLETAPPHELKNIFQLLHEILVIEDPLQVERIKFAFETENGLIALMHHSNHVDSSRCYQCVKFLVTLAQKCPTAKDYFKENSHHWSWAVQWLQKKMSEHYWAPQSNVSNETSTAKTFQRTISAQDTLAYATALLNEKDQSGSSNGSESSPANENGDRHLQQGSESPMMIGETKNDLDDVDP", "length": 2597, "header": "tr|A0A8V0ZJV2-1|A0A8V0ZQ83_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 24 OS=Gallus gallus OX=9031 GN=USP24 PE=1 SV=1 CANONICAL=A0A8V0ZQ83-1" }, "locus": { "chromosome": "8", "start_pos": 25031122, "end_pos": 24973564, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055520.1", "url": "https://www.ensembl.org/id/ENSGALT00010055520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033634.1", "url": "https://www.ensembl.org/id/ENSGALP00010033634.1" } ] } }, { "isoform_ac": "A0A8V0ZQ83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83/entry#A0A8V0ZQ83-1", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDAAAIRKALRLAKNDINEAVALLTNERPGLHYGGYEPMESGQGPPPGHGSPAGGQGSRDGDGGGGGGSGGFDPPPAYHEVVETEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLIASTYLARLGLSDSDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLVDLVAERVKQDPIPVGLLGVLTMAFNPDNEYHFKNRMKVCQRNWAEVFGEGNMHAVSPISTFQKEPHGWLVDLVNRFAELGGFSAIQSKLNSEDIELGAISALVQPFGVCAEYLNSSVVQPMLDPVIHKMIKYVQNVEEKDLKDKRLVSIPELLSGIKLLCMRFQPDLVTAVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTVSKSVKNAIDTDRLLNWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWRIQSGQSSTVIENIHTIIAAAAVKFSSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARVETTTGKVLEVLWELAHLPTLPCSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRKMKPPRKAMSSSNNESSQHNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLISCHRLAASVAGPGGLVGATLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFSLFKTFFENVNLCDHRLKRQGTQLSVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLTPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDLYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTIEAHSNETVGSIRWKIAKMLNSPVDNIQIFANDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSNSSSVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSESSSQSSKSPSLSSKHQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDEMARNCAKSFCENFLRAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDFIKDGVEALSSRPFRNVSRQASRQMSICGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVNDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKENNTLFPAGIRNRLSSSGSNCSSGSEGEPTALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLGSFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSTHPDVQKPNQFLLSVILGAQLPLWSPTSIMRGINQRLLSQCTEYFDLRCQLLDDLTSSEMEQLKISPAAMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMVGSSLIKPLLDDFLFRASRIILNSHSPSGSAAISQQDFHPKCSTADSRLAAYEVLVMLADSSPSNLQLITKELLSMHHQCDPALTKEFDYLPPVDSRSISGFVGLKNGGATCYMNAVFQQLYMQPGLPEALLSIDDDTDNPDDNVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKIGRDQIFKNTFQGIFSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKVLPNLLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGDNGRNVDQGGGGSPRKKVAPTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVVEEFELTDETLEYECFGGEYRPKVYDQSNPYPDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNSDRLSILTKLVRKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKVKHPYYPCMAKVSLQLAVQFLFQTYLRTKKKLRADTEEWIATIDALLSKSIDACQWLVEYFVGPEGRELVKTFLLECSVREVRVAVATILEKTLDSALFYQEKLKSLHQLLEVLLALLDKDVPENCKNCAQYFLLFNNFVQKQGIRASSLLLRHSALRHMINFLLGPNRQSNQNRRWSSAQAREFGYLHNTVALLVLHSDVSSQRNVAPGLFKQRPPLSITTSGPLLTLHEEVEALLFLSEGKPYLIEVMYALRELTGSLSVLIEMVVYCCFCNEHFSFTVLHFIKTQLETAPPHELKNIFQLLHEILVIEDPLQVERIKFAFETENGLIALMHHSNHVDSSRCYQCVKFLVTLAQKCPTAKDYFKENSHHWSWAVQWLQKKMSEHYWAPQSNVSNETSTAKTFQRTISAQDTLAYATALLNEKDQSGSSNGSESSPANENGDRHLQQGSESPMMIGETKNDLDDVDP", "length": 2612, "header": "tr|A0A8V0ZQ83-1|A0A8V0ZQ83_CHICK Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 24 OS=Gallus gallus OX=9031 GN=USP24 PE=1 SV=1 CANONICAL=A0A8V0ZQ83-1" }, "locus": { "chromosome": "8", "start_pos": 25031122, "end_pos": 24973564, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055509.1", "url": "https://www.ensembl.org/id/ENSGALT00010055509.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033626.1", "url": "https://www.ensembl.org/id/ENSGALP00010033626.1" } ] } }, { "isoform_ac": "A0A8V0ZS13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83/entry#A0A8V0ZS13-1", "sequence": { "sequence": "MRYIKKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLIASTYLARLGLSDSDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLVDLVAERVKQDPIPVGLLGVLTMAFNPDNEYHFKNRMKVCQRNWAEVFGEGNMHAVSPISTFQKEPHGWLVDLVNRFAELGGFSAIQSKLNSEDIELGAISALVQPFGVCAEYLNSSVVQPMLDPVIHKMIKYVQNVEEKDLKDKRLVSIPELLSGIKLLCMRFQPDLVTAVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTVSKSVKNAIDTDRLLNWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWRIQSGQSSTVIENIHTIIAAAAVKFSSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARVETTTGKVLEVLWELAHLPTLPCSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRSSQHNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLISCHRLAASVAGPGGLVGATLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFSLFKTFFENVNLCDHRLKRQGTQLSVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLTPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDLYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTIEAHSNETVGSIRWKIAKMLNSPVDNIQIFANDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSNSSSVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSESSSQSSKSPSLSSKHQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDEMARNCAKSFCENFLRAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDFIKDGVEALSSRPFRNVSRQASRQMSICGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVNDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKENNTLFPAGIRNRLSSSGSNCSSGSEGEPTALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLGSFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSTHPDVQKPNQFLLSVILGAQLPLWSPTSIMRGINQRLLSQCTEYFDLRCQLLDDLTSSEMEQLKISPAAMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMVGSSLIKPLLDDFLFRASRIILNSHSPSGSAAISQQDFHPKCSTADSRLAAYEVLVMLADSSPSNLQLITKELLSMHHQCDPALTKEFDYLPPVDSRSISGFVGLKNGGATCYMNAVFQQLYMQPGLPEALLSIDDDTDNPDDNVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKIGRDQIFKNTFQGIFSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKVLPNLLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGDNGRNVDQGGGGSPRKKVAPTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVVEEFELTDETLEYECFGGEYRPKVYDQSNPYPDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNSDRLSILTKLVRKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKVKHPYYPCMAKVSLQLAVQFLFQTYLRTKKKLRADTEEWIATIDALLSKSIDACQWLVEYFVGPEGRELVKTFLLECSVREVRVAVATILEKTLDSALFYQEKLKSLHQLLEVLLALLDKDVPENCKNCAQYFLLFNNFVQKQGIRASSLLLRHSALRHMINFLLGPNRQSNQNRRWSSAQAREFGYLHNTVALLVLHSDVSSQRNVAPGLFKQRPPLSITTSGPLLTLHEEVEALLFLSEGKPYLIEVMYALRELTGSLSVLIEMVVYCCFCNEHFSFTVLHFIKTQLETAPPHELKNIFQLLHEILVIEDPLQVERIKFAFETENGLIALMHHSNHVDSSRCYQCVKFLVTLAQKCPTAKDYFKENSHHWSWAVQWLQKKMSEHYWAPQSNVSNETSTAKTFQRTISAQDTLAYATALLNEKDQSGSSNGSESSPANENGDRHLQQGSESPMMIGETKNDLDDVDP", "length": 2500, "header": "tr|A0A8V0ZS13-1|A0A8V0ZQ83_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 24 OS=Gallus gallus OX=9031 GN=USP24 PE=1 SV=1 CANONICAL=A0A8V0ZQ83-1" }, "locus": { "chromosome": "8", "start_pos": 25019909, "end_pos": 24973564, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055495.1", "url": "https://www.ensembl.org/id/ENSGALT00010055495.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033613.1", "url": "https://www.ensembl.org/id/ENSGALP00010033613.1" } ] } }, { "isoform_ac": "A0A8V0ZS44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83/entry#A0A8V0ZS44-1", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDAAAIRKALRLAKNDINEAVALLTNERPGLHYGGYEPMESGQGPPPGHGSPAGGQGSRDGDGGGGGGSGGFDPPPAYHEVVETEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLIASTYLARLGLSDSDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLVDLVAERVKQDPIPVGLLGVLTMAFNPDNEYHFKNRMKVCQRNWAEVFGEGNMHAVSPISTFQKEPHGWLVDLVNRFAELGGFSAIQSKLNSEDIELGAISALVQPFGVCAEYLNSSVVQPMLDPVIHKMIKYVQNVEEKDLKDKRLVSIPELLSGIKLLCMRFQPDLVTAVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTVSKSVKNAIDTDRLLNWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWRIQSGQSSTVIENIHTIIAAAAVKFSSDQLNHLFVLIQKVLEVLWELAHLPTLPCSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRSSQHNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLISCHRLAASVAGPGGLVGATLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFSLFKTFFENVNLCDHRLKRQGTQLSVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLTPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDLYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTIEAHSNETVGSIRWKIAKMLNSPVDNIQIFANDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSNSSSVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSESSSQSSKSPSLSSKHQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDEMARNCAKSFCENFLRAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDFIKDGVEALSSRPFRNVSRQASRQMSICGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVNDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKENNTLFPAGIRNRLSSSGSNCSSGSEGEPTALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLGSFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSTHPDVQKPNQFLLSVILGAQLPLWSPTSIMRGINQRLLSQCTEYFDLRCQLLDDLTSSEMEQLKISPAAMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMVGSSLIKPLLDDFLFRASRIILNSHSPSGSAAISQQDFHPKCSTADSRLAAYEVLVMLADSSPSNLQLITKELLSMHHQCDPALTKEFDYLPPVDSRSISGFVGLKNGGATCYMNAVFQQLYMQPGLPEALLSIDDDTDNPDDNVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKIGRDQIFKNTFQGIFSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKVLPNLLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGDNGRNVDQGGGGSPRKKVAPTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVVEEFELTDETLEYECFGGEYRPKVYDQSNPYPDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNSDRLSILTKLVRKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKVKHPYYPCMAKVSLQLAVQFLFQTYLRTKKKLRADTEEWIATIDALLSKSIDACQWLVEYFVGPEGRELVKTFLLECSVREVRVAVATILEKTLDSALFYQEKLKSLHQLLEVLLALLDKDVPENCKNCAQYFLLFNNFVQKQGIRASSLLLRHSALRHMINFLLGPNRQSNQNRRWSSAQAREFGYLHNTVALLVLHSDVSSQRNVAPGLFKQRPPLSITTSGPLLTLHEEVEALLFLSEGKPYLIEVMYALRELTGSLSVLIEMVVYCCFCNEHFSFTVLHFIKTQLETAPPHELKNIFQLLHEILVIEDPLQVERIKFAFETENGLIALMHHSNHVDSSRCYQCVKFLVTLAQKCPTAKDYFKENSHHWSWAVQWLQKKMSEHYWAPQSNVSNETSTAKTFQRTISAQDTLAYATALLNEKDQSGSSNGSESSPANENGDRHLQQGSESPMMIGETKNDLDDVDP", "length": 2565, "header": "tr|A0A8V0ZS44-1|A0A8V0ZQ83_CHICK Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 24 OS=Gallus gallus OX=9031 GN=USP24 PE=1 SV=1 CANONICAL=A0A8V0ZQ83-1" }, "locus": { "chromosome": "8", "start_pos": 25031122, "end_pos": 24973564, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055529.1", "url": "https://www.ensembl.org/id/ENSGALT00010055529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033643.1", "url": "https://www.ensembl.org/id/ENSGALP00010033643.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1032, "start_aa": "Thr", "end_pos": 1032, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1032", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 887, "start_aa": "Thr", "end_pos": 887, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr887", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424665", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424665", "resource": "KEGG Pathway" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [ { "uniprot_canonical_ac": "B1AY13-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24", "gene_name": "Usp24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGPSPGPGGGPRGDSGSDGSGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMERCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERMKQDPIPIGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAISPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPALVTTVDALRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNADQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFEATSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAVKRSYIIKCIEDIKRPGEWSSLEKNKKDGFKSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLLACHRLAAAVAGPGGLTGLTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELVGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSSSSSGAFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSETSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTSLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEASDFTATVACFMRLSWAAAAGRLDLVGSSQPIKESNSLFPAGIRSRLSSSGSNCSSSSEGEPAALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLASFYSLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPEVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMDQLRISPATMLEDEITWLDNFEPNRTADCETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIIVNSHSPASSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGREQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVAGMARQDSSSEVGENGRNMDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSLDACQWLVEYFISSEGRELVKVFLLECSVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFSLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGVSRQNSQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISVAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALMEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEVLVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERHLQQGSESPMMIGELRSDLDDVDP", "length": 2617 }, "evidence": [ { "id": "A0A8V0ZQ83", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ83/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BND0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24", "gene_name": "USP24", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGGPSPGPGGGSRGDGGGCDGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLAVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILNTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPDLVTVVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLDKNKKDGFKSSQINNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLTGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDSIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSETSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARNCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTLPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVGDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKESNSLFPAGIRNRLSSSGSNCSSGSEGDPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLENFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREETFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSTDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPVRIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIKAGDLLLKHSALRHMISFLLGASRQSTQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGVFKQRPPISIAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERHLQQGSESPMMIGELRSDLDDVDP", "length": 2617 }, "evidence": [ { "id": "A0A8V0ZQ83", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ83/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1LSM0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24", "gene_name": "Usp24", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGPSPGLGGGPRGDGGGEGSGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGVEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCKRFMERCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERMKQDPIPIGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALVQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAIKLLCMRFQPDLVTIVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNADQLNHLFVLIQKSWETETDRVRQKLLSLIGRIGREARFEATSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAVKRSYIIKCIEDIKRPGEWSGLEKNKKDGFKSSQHNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLLACHRLAAAVAGPGGLTGLTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELVGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQVLTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSETSSPSSKSPSLSSKQQQQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTSLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEANDFTATVACFMRLSWAAAAGRLDLVGSSQPIKESNSLFPAGIRNRLSSSGSNCSSSSEGEPAALHAGICVRQQSVSTKDALIAGEALSLLVTCLQLRSQQLASFYSLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPEVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRVSPAAMLEDEVTWLDNFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEVLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTVNSRLAAYEVLVMLADSSPSNLQIITKELLSMHHQPDPALTKEFDYLPPVDSRSISGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGREQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVAGMARQDSSSEVGENGRNMDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYPDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPHYPCMAKVSLQLAVQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSLDACQWLVEYFISSEGRELVKVFLLECSVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFSLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGVSQQNSQIRRWSSAQAREFGNLHNTVALLVLHTDVSSQRNVAPGIFKQRPPISVAPSSPLLPLHEEVEALLFLSEGKPYLLEVMFALRELTGSLLALMEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVMEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGERRLQQGSESPMMIGELRSDLDDVDP", "length": 2617 }, "evidence": [ { "id": "A0A8V0ZQ83", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ83/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q6K1-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24", "gene_name": "usp24", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMETEEEQHMTTLLCMGFPDPVAIRKALRLAKNDINEAVALLTNESPGLGYGYEPMESGPSPGSGDGENSGRTVTGGFDPPPAYHDVVESERSNDENGNCSGNSMEFPTTNLYELESRVFTDHWSIPYKREESLGKCLIASTCLARHGLADADENCKRFIDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLVDLVAERVKQDPIPIGLMGVLTMAFNPDNEYHFKNRMKACQRNWAEVFGEDSMFAVSPSSSYQKEPHGWLVDLVNRFGEMGGFTAIQCKLNQEEIEIGCVSALVQPLGVCAEYLNSSLVQPMLDPVIHKMITYVQNLEEKDLKDKRLVSIPELLSAIKLLCMRFQRELVNVVDDLRLDILLRMLKTPHFSAKMNSLKEVTKLIEESTVSKTVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELSKIWKIQAGQSSTVIENIHTIIAAAAVKFNFDQLSHLFVLIQKSWEVESDRVRQKLLSLIGRIGREARSEATTGKVLEVLWELAHLPTLPTSLVQQALEEHLTILSDAYAVKETIKRNYIIKCIEDIKKMQIQEDSKSPSETQVSFLTGTWGKKKPSSLAKSSQQTNPQTVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLITGSLVSCHRLAVSVAGSNGLSGSTLVDGRYSYQEYLEGHLKFLAFFLQEASLYLVWNRAKEIWECLVSGMDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLEPYEITMNGFNLFKTFFENVNLSDHRLKRQGTQLCVERLDLAGMDFIWRIAMESPDEDIANEAIQLIITYSYINLNPKMKKDSVSLHKKFIADCYKRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPSRSSKLVIIERLLLLAERYVITIEDLYSVPRTILPHGASFHGHPVTLHITYESTKDTFTLEAHSNETIGSIRWKIADQLSCPVDNVQIFANDSMLTMNRDQKLLNQLGFSDEQSLTVKSSGTGTPSGSSADSSASASSSSSGVFNSAYALEQEKSLPGVVMALVCNVFEMLYQLANLEEPRITLRVRKLLLLIPTDPEVQDALDNFVPKESSVWSHQKTLFTLGSGSQASKSPSLSSKQQHQQSAASILESLFRSSAPGMSTFRVLYNLEVLSSKLMPTSDDEMAKTSVKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQAMPSILDEELSKDDTLSSRPFRNAGRQSGRQLSVCGTPEKSSYRQVSVSDRSSIRVEEIIPAARVAIQTMEVGDFTSTVACFMRLTWAAAAGRLDLVGSSQPIRETTNSLLPLGVRSRVSSTGSNCSSSSEGEVTTLQAGICVKQLFVSIKDTIIAREALSLLVTCLQLRSQQLCSFYSLLSVNDFIIDILLGSPSGEIRRVACDQLYTLSQSDTSAYPDLQKPNLFLLKVVLTAQLPLWSPTSIMRGVNQRLLSQCTEYFDLRCQLLDDLTTSEMEQLQIGPAAMLEDEISWLDNFEPTWTTELETSEADNILLAGHLRLIKTLLSLCGTEKEQFGPSLIQQLLDDFLFRASRIILNSDSSSSTTASIHDFHPKCSTVSSRLAAYEVLVMLADSSLTNLQLITKELLSMHHQSDPSLSKEFDYLPPVDSRSISGFVGLKNGGATCYMNAVFQQLYMQPGLPEGVLSIEDDTENPEESVFCQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLVDQLDEHLKKIGREQIFKNTFQGIFSDQKICKDCPHRYEREETFMALNLGVTSCQSLEISLDQFVRGEVLDGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWVLNMEPYTVSGMARQDSSADHGENGRGGEAGSGGSPRKKVTISENYELVGVVVHSGQAHAGHYYSFIKDRRGSARGRWYKFNDNVVEEFDMNDETLEYECFGGEYRPKVYDQSNPYPDVRRRYWNAYMLFYQRISDQNSPVLPKKSRVSIMRQEAEDLSLSAPSSPEISPQSSPRPPRANNDRLTLLTRLVKKGEKKGLFVEKMPARIFQMVRDENLKFMKNRDVYNSDYFSFTLSLASVNATKLKHASYQAMAKTSLQLAVQFLLHTYLRTKKKLRVDTEEWIATVEVLLSKSSEACQWMVQYLVAPEGREIIKICLLECSVREVRVVVATILEKTLESALYFQDAGLDCLLDMLLSLLDKDVPDNCKNCSQYFSLFSNFAQRGCGPCQLLLKHSAYRRMLVFLLGPNRQNNQHRRWSSAQAREFLHLHNTLALMVLHTDLTSQRTEAQGVFKQASSGLVAPSSVLMPLHPDINTLLFKADGQAYLMEVMFAMRELSGPLSFLIEMITYSSFCNEPFSLGVLQLLKNHLETAPPHELKNVFQMLLEILMLEDPLQSQRLKFAFESEKGLLALMHQSNNVDSSRCYQCVKFLVTLAQKCSPAKDYFKELSGHWSWAVQWLQKKMSEHYWTPQSNVSNETSTAKTFQRTISAQDTLAYATALLNEKDQSGSSNGSDGSPANENSDRSLRQGSESPMMLGDSRSDLEDVDP", "length": 2621 }, "evidence": [ { "id": "A0A8V0ZQ83", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ83/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9UPU5-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24", "gene_name": "USP24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESEEEQHMTTLLCMGFSDPATIRKALRLAKNDINEAVALLTNERPGLDYGGYEPMDSGGGPSPGPGGGPRGDGGGDGGGGGPSRGGSTGGGGGFDPPPAYHEVVDAEKNDENGNCSGEGIEFPTTNLYELESRVLTDHWSIPYKREESLGKCLLASTYLARLGLSESDENCRRFMDRCMPEAFKKLLTSSAVHKWGTEIHEGIYNMLMLLIELVAERIKQDPIPTGLLGVLTMAFNPDNEYHFKNRMKVSQRNWAEVFGEGNMFAVSPVSTFQKEPHGWVVDLVNKFGELGGFAAIQAKLHSEDIELGAVSALIQPLGVCAEYLNSSVVQPMLDPVILTTIQDVRSVEEKDLKDKRLVSIPELLSAVKLLCMRFQPDLVTIVDDLRLDILLRMLKSPHFSAKMNSLKEVTKLIEDSTLSKSVKNAIDTDRLLDWLVENSVLSIALEGNIDQAQYCDRIKGIIELLGSKLSLDELTKIWKIQSGQSSTVIENIHTIIAAAAVKFNSDQLNHLFVLIQKSWETESDRVRQKLLSLIGRIGREARFETTSGKVLDVLWELAHLPTLPSSLIQQALEEHLTILSDAYAVKEAIKRSYIIKCIEDIKRPGEWSGLEKNKKDGFKSSQLNNPQFVWVVPALRQLHEITRSFIKQTYQKQDKSIIQDLKKNFEIVKLVTGSLIACHRLAAAVAGPGGLSGSTLVDGRYTYREYLEAHLKFLAFFLQEATLYLGWNRAKEIWECLVTGQDVCELDREMCFEWFTKGQHDLESDVQQQLFKEKILKLESYEITMNGFNLFKTFFENVNLCDHRLKRQGAQLYVEKLELIGMDFIWKIAMESPDEEIANEAIQLIINYSYINLNPRLKKDSVSLHKKFIADCYTRLEAASSALGGPTLTHAVTRATKMLTATAMPTVATSVQSPYRSTKLVIIERLLLLAERYVITIEDFYSVPRTILPHGASFHGHLLTLNVTYESTKDTFTVEAHSNETIGSVRWKIAKQLCSPVDNIQIFTNDSLLTVNKDQKLLHQLGFSDEQILTVKTSGSGTPSGSSADSSTSSSSSSSGVFSSSYAMEQEKSLPGVVMALVCNVFDMLYQLANLEEPRITLRVRKLLLLIPTDPAIQEALDQLDSLGRKKTLLSESSSQSSKSPSLSSKQQHQPSASSILESLFRSFAPGMSTFRVLYNLEVLSSKLMPTADDDMARSCAKSFCENFLKAGGLSLVVNVMQRDSIPSEVDYETRQGVYSICLQLARFLLVGQTMPTLLDEDLTKDGIEALSSRPFRNVSRQTSRQMSLCGTPEKSSYRQLSVSDRSSIRVEEIIPAARVAIQTMEVSDFTSTVACFMRLSWAAAAGRLDLVGSSQPIKESNSLCPAGIRNRLSSSGSNCSSGSEGEPVALHAGICVRQQSVSTKDSLIAGEALSLLVTCLQLRSQQLASFYNLPCVADFIIDILLGSPSAEIRRVACDQLYTLSQTDTSAHPDVQKPNQFLLGVILTAQLPLWSPTSIMRGVNQRLLSQCMEYFDLRCQLLDDLTTSEMEQLRISPATMLEDEITWLDNFEPNRTAECETSEADNILLAGHLRLIKTLLSLCGAEKEMLGSSLIKPLLDDFLFRASRIILNSHSPAGSAAISQQDFHPKCSTANSRLAAYEVLVMLADSSPSNLQIIIKELLSMHHQPDPALTKEFDYLPPVDSRSSSGFVGLRNGGATCYMNAVFQQLYMQPGLPESLLSVDDDTDNPDDSVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQQDAYEFFTSLIDQMDEYLKKMGRDQIFKNTFQGIYSDQKICKDCPHRYEREEAFMALNLGVTSCQSLEISLDQFVRGEVLEGSNAYYCEKCKEKRITVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWMLNMEPYTVSGMARQDSSSEVGENGRSVDQGGGGSPRKKVALTENYELVGVIVHSGQAHAGHYYSFIKDRRGCGKGKWYKFNDTVIEEFDLNDETLEYECFGGEYRPKVYDQTNPYTDVRRRYWNAYMLFYQRVSDQNSPVLPKKSRVSVVRQEAEDLSLSAPSSPEISPQSSPRPHRPNNDRLSILTKLVKKGEKKGLFVEKMPARIYQMVRDENLKFMKNRDVYSSDYFSFVLSLASLNATKLKHPYYPCMAKVSLQLAIQFLFQTYLRTKKKLRVDTEEWIATIEALLSKSFDACQWLVEYFISSEGRELIKIFLLECNVREVRVAVATILEKTLDSALFYQDKLKSLHQLLEVLLALLDKDVPENCKNCAQYFFLFNTFVQKQGIRAGDLLLRHSALRHMISFLLGASRQNNQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISIAPSSPLLPLHEEVEALLFMSEGKPYLLEVMFALRELTGSLLALIEMVVYCCFCNEHFSFTMLHFIKNQLETAPPHELKNTFQLLHEILVIEDPIQVERVKFVFETENGLLALMHHSNHVDSSRCYQCVKFLVTLAQKCPAAKEYFKENSHHWSWAVQWLQKKMSEHYWTPQSNVSNETSTGKTFQRTISAQDTLAYATALLNEKEQSGSSNGSESSPANENGDRHLQQGSESPMMIGELRSDLDDVDP", "length": 2620 }, "evidence": [ { "id": "A0A8V0ZQ83", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ83/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ83", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1046, "end_pos": 1048, "annotation": "n_glycosylation_sequon" }, { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1267, "end_pos": 1269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1350, "end_pos": 1352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1368, "end_pos": 1370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1543, "end_pos": 1545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1982, "end_pos": 1984, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2141, "end_pos": 2143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2537, "end_pos": 2539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2540, "end_pos": 2542, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2575, "end_pos": 2577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 612, "end_pos": 614, "annotation": "n_glycosylation_sequon" }, { "start_pos": 841, "end_pos": 843, "annotation": "n_glycosylation_sequon" }, { "start_pos": 846, "end_pos": 848, "annotation": "n_glycosylation_sequon" }, { "start_pos": 956, "end_pos": 958, "annotation": "n_glycosylation_sequon" }, { "start_pos": 973, "end_pos": 975, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-GGA-5696997", "name": "USP24 deubiquitinates DDB2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZQ83-1" ], "evidence": [ { "id": "R-GGA-5696997", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5696997" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZQ83", "gene_name": "USP24", "activity": [ { "ec_number": "3.4.19.12", "activity": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "A0A8V0ZQ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" } ] }, { "ec_number": "3.4.19.12", "activity": "", "evidence": [ { "id": "A0A8V0ZQ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 44, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 1681, "end_pos": 2034, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQ83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ83" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 953, "end_pos": 1032, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 887, 1032 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1046, "end_pos": 1048 }, { "start_pos": 109, "end_pos": 111 }, { "start_pos": 1267, "end_pos": 1269 }, { "start_pos": 1350, "end_pos": 1352 }, { "start_pos": 1368, "end_pos": 1370 }, { "start_pos": 1543, "end_pos": 1545 }, { "start_pos": 1982, "end_pos": 1984 }, { "start_pos": 2141, "end_pos": 2143 }, { "start_pos": 2537, "end_pos": 2539 }, { "start_pos": 2540, "end_pos": 2542 }, { "start_pos": 2575, "end_pos": 2577 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 612, "end_pos": 614 }, { "start_pos": 841, "end_pos": 843 }, { "start_pos": 846, "end_pos": 848 }, { "start_pos": 956, "end_pos": 958 }, { "start_pos": 973, "end_pos": 975 }, { "start_pos": 999, "end_pos": 1001 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQH2-1", "uniprot_ac": "A0A8V0ZQH2", "uniprot_id": "A0A8V0ZQH2_CHICK", "mass": { "chemical_mass": 83119.0, "monoisotopic_mass": 83119.0 }, "refseq": { "ac": "NP_001376286", "name": "ephexin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376286" }, "gene_names": [ { "name": "NGEF", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2" } ] }, { "name": "NGEF", "type": "synonym", "evidence": [ { "id": "NP_001376286", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376286" } ] }, { "name": "ephexin-1", "type": "synonym", "evidence": [ { "id": "NP_001376286", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376286" } ] } ], "protein_names": [ { "name": "Neuronal guanine nucleotide exchange factor", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2/entry#names_and_taxonomy" } ] }, { "name": "ephexin-1", "type": "synonym", "evidence": [ { "id": "NP_001376286", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376286" } ] }, { "name": "ephexin1", "type": "synonym", "evidence": [ { "id": "NP_001376286", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376286" } ] }, { "name": "guanine nucleotide exchange factor", "type": "synonym", "evidence": [ { "id": "NP_001376286", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376286" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.269417.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. On Dec 3, 2021 this sequence version replaced NP_001376286.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376286", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376286" } ] }, { "annotation": "We found ephexin1 essential for the development of limb nerves toward their muscle targets, concluding that it functions as an intermediary to relay Eph signaling in this context", "evidence": [ { "database": "RefSeq", "id": "NP_001376286", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376286" }, { "database": "PubMed", "id": "29363583", "url": "https://glygen.org/publication/PubMed/29363583" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NGEF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2", "locus": { "chromosome": "9", "start_pos": 688607, "end_pos": 734508, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022873", "url": "https://www.ensembl.org/id/ENSGALG00010022873" } ] } } ], "crossref": [ { "id": "A0A8V0ZQH2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01221", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01221", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424744", "url": "https://www.ncbi.nlm.nih.gov/gene/424744", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SQTICHS", "url": "https://omabrowser.org/oma/group/SQTICHS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK29", "url": "https://www.orthodb.org/?gene=A0A8V0ZK29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK34", "url": "https://www.orthodb.org/?gene=A0A8V0ZK34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQG4", "url": "https://www.orthodb.org/?gene=A0A8V0ZQG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQH2", "url": "https://www.orthodb.org/?gene=A0A8V0ZQH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZT75", "url": "https://www.orthodb.org/?gene=A0A8V0ZT75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12845:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12845:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-3928663", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928663", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376286", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376286", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZT75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGHGGEAAGGLQQGISRSLSVSEGEEESEGADSETYERDSHTHYIAIQRNSKYYRSMRLPNRSKRKTAREAIHAGRAAGSLKNNESVKEPLNVLPPMGSPAPVDSNQTTLELLIQRLLPSYPRYRGNLPGSPSPAPPPLPPELLGSRLPPSAMELLAAALSATCALDQDGSAGQPGRNPPAASEDSPNAAEAPPPAHPMTTDSWRNLIEHIGLLYQEYRDKSTRQEIETRRLQDSQTDPEESSPSEETPPETEPASTPESKAAPQINLLRNSNSRFNLWQDLPEIRSSGILSILQPDEIKLQEAMFELVTSEASYCKSLNLLVSHFMENERLKKILHQSEAHILFSNVLDVKAVSERFLLDLERRVEENIVISDVCDIVYQHTVDHFSVYITYVSNQTYQERTYKQLLQDKPAFREVITQLELDPMCRGLSFSSFLILPFQRITRLKLLVQNILKKVEEKSERETTALEAHKELETVVKACNEGVRKMSRTEQMISIQKKLEFKIKSVPIISHSRWLLKQGELQQMNGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQSLANVFILRLLENADDREASYMLKASSQSEMKRWMISLAPNRRTKFVSFTSRLSDCPQIQCVHPYVAQQPDELSLELADVLNILDKTDDGWIFGERLHDQERGWFPSSIGEEILNPKIRAQNLKECFRVHKSDDSQRRKLGSRNRQ", "length": 732, "header": "tr|A0A8V0ZQH2-1|A0A8V0ZQH2_CHICK Isoform 1 of Neuronal guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=NGEF PE=4 SV=1 CANONICAL=A0A8V0ZQH2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZK29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2/entry#A0A8V0ZK29-1", "sequence": { "sequence": "MELLAAALSATCALDQDGSAGQPGRNPPAASEDSPNAAEAPPPAHPMTTDSWRNLIEHIGLLYQEYRDKSTRQEIETRRLQDSQTDPEESSPSEETPPETEPASTPESKAAPQINLLRNSNSRFNLWQDLPEIRSSGILSILQPDEIKLQEAMFELVTSEASYCKSLNLLVSHFMENERLKKILHQSEAHILFSNVLDVKAVSERFLLDLERRVEENIVISDVCDIVYQHTVDHFSVYITYVSNQTYQERTYKQLLQDKPAFREVITQLELDPMCRGLSFSSFLILPFQRITRLKLLVQVVKACNEGVRKMSRTEQMISIQKKLEFKIKSVPIISHSRWLLKQGELQQMNGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQSLANVFILRLLENADDREASYMLKASSQSEMKRWMISLAPNRRTKFVSFTSRLSDCPQIQCVHPYVAQQPDELSLELADVLNILDKTDDGWIFGERLHDQERGWFPSSIGEEILNPKIRAQNLKECFRVHKSDDSQRRKLGSRNRQ", "length": 554, "header": "tr|A0A8V0ZK29-1|A0A8V0ZQH2_CHICK Computationally mapped isoform of Neuronal guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=NGEF PE=4 SV=1 CANONICAL=A0A8V0ZQH2-1" }, "locus": { "chromosome": "9", "start_pos": 712010, "end_pos": 690641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055665.1", "url": "https://www.ensembl.org/id/ENSGALT00010055665.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033714.1", "url": "https://www.ensembl.org/id/ENSGALP00010033714.1" } ] } }, { "isoform_ac": "A0A8V0ZK34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2/entry#A0A8V0ZK34-1", "sequence": { "sequence": "MELLAAALSATCALDQDGSAGQPGRNPPAASEDSPNAAEAPPPAHPMTTDSWRNLIEHIGLLYQEYRDKSTRQEIETRRLQDSQTDPEESSPSEETPPETEPASTPESKAAPQINLLRNSNSRFNLWQDLPEIRSSGILSILQPDEIKLQEAMFELVTSEASYCKSLNLLVSHFMENERLKKILHQSEAHILFSNVLDVKAVSERQDKPAFREVITQLELDPMCRGLSFSSFLILPFQRITRLKLLVQNILKKVEEKSERETTALEAHKELETVVKACNEGVRKMSRTEQMISIQKKLEFKIKSVPIISHSRWLLKQGELQQMNGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQSLANVFILRLLENADDREASYMLKASSQSEMKRWMISLAPNRRTKFVSFTSRLSDCPQIQCVHPYVAQQPDELSLELADVLNILDKTDDGWIFGERLHDQERGWFPSSIGEEILNPKIRAQNLKECFRVHKSDDSQRRKLGSRNRQ", "length": 528, "header": "tr|A0A8V0ZK34-1|A0A8V0ZQH2_CHICK Computationally mapped isoform of Neuronal guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=NGEF PE=4 SV=1 CANONICAL=A0A8V0ZQH2-1" }, "locus": { "chromosome": "9", "start_pos": 712010, "end_pos": 690641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055676.1", "url": "https://www.ensembl.org/id/ENSGALT00010055676.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033719.1", "url": "https://www.ensembl.org/id/ENSGALP00010033719.1" } ] } }, { "isoform_ac": "A0A8V0ZQG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2/entry#A0A8V0ZQG4-1", "sequence": { "sequence": "MGSLKNNESVKEPLNVLPPMGSPAPVDSNQTTLELLIQRLLPSYPRYRGNLPGSPSPAPPPLPPELLGSRLPPSAMELLAAALSATCALDQDGSAGQPGRNPPAASEDSPNAAEAPPPAHPMTTDSWRNLIEHIGLLYQEYRDKSTRQEIETRRLQDSQTDPEESSPSEETPPETEPASTPESKAAPQINLLRNSNSRFNLWQDLPEIRSSGILSILQPDEIKLQEAMFELVTSEASYCKSLNLLVSHFMENERLKKILHQSEAHILFSNVLDVKAVSERFLLDLERRVEENIVISDVCDIVYQHTVDHFSVYITYVSNQTYQERTYKQLLQDKPAFREVITQLELDPMCRGLSFSSFLILPFQRITRLKLLVQNILKKVEEKSERETTALEAHKELETVVKACNEGVRKMSRTEQMISIQKKLEFKIKSVPIISHSRWLLKQGELQQMNGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQSLANVFILRLLENADDREASYMLKASSQSEMKRWMISLAPNRRTKFVSFTSRLSDCPQIQCVHPYVAQQPDELSLELADVLNILDKTDDGWIFGERLHDQERGWFPSSIGEEILNPKIRAQNLKECFRVHKSDDSQRRKLGSRNRQ", "length": 654, "header": "tr|A0A8V0ZQG4-1|A0A8V0ZQG4_CHICK Computationally mapped isoform of Neuronal guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=NGEF PE=4 SV=1 CANONICAL=A0A8V0ZQH2-1" }, "locus": { "chromosome": "9", "start_pos": 722493, "end_pos": 690641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055679.1", "url": "https://www.ensembl.org/id/ENSGALT00010055679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033721.1", "url": "https://www.ensembl.org/id/ENSGALP00010033721.1" } ] } }, { "isoform_ac": "A0A8V0ZQH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2/entry#A0A8V0ZQH2-1", "sequence": { "sequence": "MDGHGGEAAGGLQQGISRSLSVSEGEEESEGADSETYERDSHTHYIAIQRNSKYYRSMRLPNRSKRKTAREAIHAGRAAGSLKNNESVKEPLNVLPPMGSPAPVDSNQTTLELLIQRLLPSYPRYRGNLPGSPSPAPPPLPPELLGSRLPPSAMELLAAALSATCALDQDGSAGQPGRNPPAASEDSPNAAEAPPPAHPMTTDSWRNLIEHIGLLYQEYRDKSTRQEIETRRLQDSQTDPEESSPSEETPPETEPASTPESKAAPQINLLRNSNSRFNLWQDLPEIRSSGILSILQPDEIKLQEAMFELVTSEASYCKSLNLLVSHFMENERLKKILHQSEAHILFSNVLDVKAVSERFLLDLERRVEENIVISDVCDIVYQHTVDHFSVYITYVSNQTYQERTYKQLLQDKPAFREVITQLELDPMCRGLSFSSFLILPFQRITRLKLLVQNILKKVEEKSERETTALEAHKELETVVKACNEGVRKMSRTEQMISIQKKLEFKIKSVPIISHSRWLLKQGELQQMNGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQSLANVFILRLLENADDREASYMLKASSQSEMKRWMISLAPNRRTKFVSFTSRLSDCPQIQCVHPYVAQQPDELSLELADVLNILDKTDDGWIFGERLHDQERGWFPSSIGEEILNPKIRAQNLKECFRVHKSDDSQRRKLGSRNRQ", "length": 732, "header": "tr|A0A8V0ZQH2-1|A0A8V0ZQH2_CHICK Isoform 1 of Neuronal guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=NGEF PE=4 SV=1 CANONICAL=A0A8V0ZQH2-1" }, "locus": { "chromosome": "9", "start_pos": 725025, "end_pos": 690641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055698.1", "url": "https://www.ensembl.org/id/ENSGALT00010055698.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033731.1", "url": "https://www.ensembl.org/id/ENSGALP00010033731.1" } ] } }, { "isoform_ac": "A0A8V0ZT75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2/entry#A0A8V0ZT75-1", "sequence": { "sequence": "LTTAHWFLLRDFPSLLYQEYRDKSTRQEIETRRLQDSQTDPEESSPSEETPPETEPASTPESKAAPQINLLRNSNSRFNLWQDLPEIRSSGILSILQPDEIKLQEAMFELVTSEASYCKSLNLLVSHFMENERLKKILHQSEAHILFSNVLDVKAVSERFLLDLERRVEENIVISDVCDIVYQHTVDHFSVYITYVSNQTYQERTYKQLLQDKPAFREVITQLELDPMCRGLSFSSFLILPFQRITRLKLLVQNILKKVEEKSERETTALEAHKELETVVKACNEGVRKMSRTEQMISIQKKLEFKIKSVPIISHSRWLLKQGELQQMNGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQSLANVFILRLLENADDREASYMLKASSQSEMKRWMISLAPNRRTKFVSFTSRLSDCPQIQCVHPYVAQQPDELSLELADVLNILDKTDDGWIFGERLHDQERGWFPSSIGEEILNPKIRAQNLKECFRVHKSDDSQRRKLGSRNRQ", "length": 533, "header": "tr|A0A8V0ZT75-1|A0A8V0ZQH2_CHICK Computationally mapped isoform of Neuronal guanine nucleotide exchange factor OS=Gallus gallus OX=9031 GN=NGEF PE=4 SV=1 CANONICAL=A0A8V0ZQH2-1" }, "locus": { "chromosome": "9", "start_pos": 708472, "end_pos": 690641, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055660.1", "url": "https://www.ensembl.org/id/ENSGALT00010055660.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033712.1", "url": "https://www.ensembl.org/id/ENSGALP00010033712.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Ephexin1 Is Required for Eph-Mediated Limb Trajectory of Spinal Motor Axons.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2018", "authors": "Chang CJ, Chang MY, Chou SY, Huang CC, Chuang JY, Hsu TI, Chang HF, Wu YH, Wu CC, Morales D, Kania A, Kao TJ", "evidence": [ { "database": "RefSeq", "id": "NP_001376286", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376286" } ], "reference": [ { "type": "PubMed", "id": "29363583", "url": "https://glygen.org/publication/PubMed/29363583" } ] } ], "pathway": [ { "id": "R-GGA-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-GGA-3928663", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3928663", "resource": "Reactome", "description": "EPHA-mediated growth cone collapse" }, { "id": "R-GGA-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "E7FDB4-1", "protein_name": "Ephexin-1 isoform X1", "gene_name": "ngef", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMAMTALFRGKWGHNNKPQEVQTKPRTPVPQLPSEDDENEDETLRAPIRRNSRFYRSMRKKKSAGPSEQQESPSSSPKPTVDPASYNRLSPAAANRVPLSPRLQKSPPSRSGISLLSNGVQGGVRSRSPLASPGDWPRRLEMEELSERTTSACTMQDNDNHSTADPDNITFRLVRNGDSPQKMAVENSCHNLNIMKNVDVLYQEYRDTSKQQEIDQRRQRDGLPTAGSGVLAAPALQLQLRSSTNSLNLWQNLDAVKKSGLLQTLEPKEIILQEAMFELVTSEASYYKSLELLETHFLRNPLLVNTLSQSDMHFLFSNITDIMKASEKFLMDLEHRIEESILISDVCDIVHFHAVNHFQVFISYVINQVYQETNYRRILQENCAFRENMAILENQPKVKGLSFTSFLILPFQRITRLKLLVQNILKRVEENSEKERTAILAHQELEKIVKQCNEGARKMSRTEELISIEKTLEFKSKSVPVISHSRWLLKKGEVQQMSGPKSTRTMRSRKLYHPIYLFLFNNLLLITKRNSSGDKFQVLDSCSRSMLRTEDLEDQGQMLACVFVLKLLENQEDREVSYMLKTESVSDKLRWICALTPNRRTRFLSTSTHEPDSPQVQCIQSYSSQEPDELSVEMADVLHILECTDDGWILGERLHDGERGWFPNRVVERIMSAEVRAQNLKECQRIQQAQEGAQGTRAASRGRVAVRNSQYNASWTDL", "length": 718 }, "evidence": [ { "id": "A0A8V0ZQH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZQH2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SM48-1", "protein_name": "Neuronal guanine nucleotide exchange factor", "gene_name": "NGEF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELLAAAFSAACAVDHDSSTSESDARDSAAGHLPGSESSSTPGNGATPEECPALADSPTTLTEALQMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQGNADRSPASEEAPEEDEEEEEEELPSPPERKALPQICLLSNPHSRFNLWQDLPEIRSSGVLDILQPEEIRLQEAMFELVTSEASYYKSLSLLVSHFMENERLKKLLHPSEAHILFSNVLDVMGVSERFLLELERRMEENIVISDVCDIVYRYAANHFSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCRGLPLSSFLILPFQRITRLKLLVQNILKRVEESSEREATALDAHKELELVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKATSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILDKTEDGWIFGERLHDQERGWFPSNMAEEILNPKIRSQNLKECFRVHKMDDPQRSQNKDRRKLGSRNRQ", "length": 617 }, "evidence": [ { "id": "A0A8V0ZQH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZQH2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5BKC9-1", "protein_name": "Ephexin-1", "gene_name": "Ngef", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKNSEDQGKPQRKSVSSLWKSKHGPAEMRPELPPETAKETQNEEPRCLIPIQRNSLFNRAMRHKHKARSMSERRANDQAGDLPETRKSVNEPLAFNLPQGRLPPWRTPAQRGPGAQEASESSSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQGNSDGSQAGEDNAEEEEEEEEEPASPPERRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEETKLQEAMFELVTSEASYYKSLNLLVSHFMENERLKKILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKTAFRELIAQLELDPKCKGLPLSSFLILPFQRITRLKLLVQNILKRVEEGSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMEDPQRSQNKDRRKLGSRNRQ", "length": 701 }, "evidence": [ { "id": "A0A8V0ZQH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZQH2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CHT1-1", "protein_name": "Ephexin-1", "gene_name": "Ngef", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METKNSEDWGKPQRKSESSSRKSNHGPAEMRPALPPENREAPETGEETQNEEPRRLIPIQRHSLFNRAVRHRHKARSTSERRASDQADLPKMGKSVNERSAFNLPQGRLSPWRTPAQRDTGAQEASESSSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQGNSDGSQVGEDAGEEEEEEEEGEEEELASPPERRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEEIRLQEAMFELVTSEASYYKSLNLLVSHFMENERLKKILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCKGLPFSSFLILPFQRITRLKLLVQNILKRVEERSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMEDPQRSQNKDRRKLGSRNRQ", "length": 710 }, "evidence": [ { "id": "A0A8V0ZQH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZQH2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N5V2-1", "protein_name": "Ephexin-1", "gene_name": "NGEF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METRESEDLEKTRRKSASDQWNTDNEPAKVKPELLPEKEETSQADQDIQDKEPHCHIPIKRNSIFNRSIRRKSKAKARDNPERNASCLADSQDNGKSVNEPLTLNIPWSRMPPCRTAMQTDPGAQEMSESSSTPGNGATPEEWPALADSPTTLTEALRMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIEDNTNGSPASEDTPEEEEEEEEEEEPASPPERKTLPQICLLSNPHSRFNLWQDLPEIRSSGVLEILQPEEIKLQEAMFELVTSEASYYKSLNLLVSHFMENERIRKILHPSEAHILFSNVLDVLAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCRGLPFSSFLILPFQRITRLKLLVQNILKRVEERSERECTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFHEIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILDKTDDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMDDPQRSQNKDRRKLGSRNRQ", "length": 710 }, "evidence": [ { "id": "A0A8V0ZQH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZQH2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2" } ], "pmid": "" }, { "name": "ephrin receptor binding", "id": "GO:0046875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046875", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2" } ], "pmid": "" }, { "name": "ephrin receptor signaling pathway", "id": "GO:0048013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH2" } ], "pmid": "" }, { "name": "negative regulation of dendritic spine morphogenesis", "id": "GO:0061002", "url": 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"header": "tr|A0A8V0ZQY6-1|A0A8V0ZQY6_CHICK Isoform 1 of Poly(ADP-ribose) polymerase family member 6 OS=Gallus gallus OX=9031 GN=PARP6 PE=3 SV=1 CANONICAL=A0A8V0ZQY6-1" }, "locus": { "chromosome": "10", "start_pos": 1634334, "end_pos": 1626875, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052155.1", "url": "https://www.ensembl.org/id/ENSGALT00010052155.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031150.1", "url": "https://www.ensembl.org/id/ENSGALP00010031150.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY6" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY6" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY6" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activator activity", "id": "GO:0043539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY6" } ], "pmid": "" }, { "name": "NAD+-protein-cysteine ADP-ribosyltransferase activity", "id": "GO:0140803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY6" } ], "pmid": "" }, { "name": "NAD+-protein-aspartate ADP-ribosyltransferase activity", "id": "GO:0140806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140806", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein auto-ADP-ribosylation", "id": "GO:0070213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070213", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY6" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY6" } ], "pmid": "" }, { "name": "endoplasmic reticulum tubular network", "id": "GO:0071782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZQY1" } ] }, { "name": "TRPV6", "type": "synonym", "evidence": [ { "id": "XP_004938199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938199" } ] } ], "protein_names": [ { "name": "Transient receptor potential cation channel subfamily V member 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY1/entry#names_and_taxonomy" } ] }, { "name": "transient receptor potential cation channel subfamily V member 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004938199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938199" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004938199.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004938199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938199" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRPV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY1", "locus": { "chromosome": "1", "start_pos": 77904604, "end_pos": 77873795, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021482", "url": "https://www.ensembl.org/id/ENSGALG00010021482" } ] } } ], "crossref": [ { "id": "A0A8V0ZQY1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22192", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22192", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22296", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22296", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418307", "url": "https://www.ncbi.nlm.nih.gov/gene/418307", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418307", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418307", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MIYSIFL", "url": "https://omabrowser.org/oma/group/MIYSIFL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZK71", "url": "https://www.orthodb.org/?gene=A0A8V0ZK71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQY1", "url": "https://www.orthodb.org/?gene=A0A8V0ZQY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10582", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10582", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10582:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10582:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-3295583", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004938199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004938199", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZK71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZK71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVPLFGDSKPFYFRIWNGLSQKLQGKKSWDKHLDEIYLLQQKRICESPLLQAAKENNIPAITKLLADGTCDIYQRGAVGETALHVAALYDNVEAAVALMEAAPELVNERMTSELYEGQTALHIAAVNQNITLVKALLKRGANTCTAQATGHFFRRSSQNLLYFGEHVLSFAACVGNEEIVQLLIENGADIRAQDYLGNTVLHILVLQPNKTFACHMYSLILSYDQSKEGPRSLELIPNNEGLTPFKLAGVEGNTVMFQYLMQRRKHNLWSFGPLTTVLYDLTEIDSWAEDQSFLELIVSTKKREARQILDLTPVKELVSLKWNMYGRPYFCFLALFYVLYMVCFTMCCVYRPLKPRTGNKTSSRDNTVYVQKMLQESYVTYEDELRLVGELITVIGAVVILILEIPDILRVGAAKYFGQTILGGPFHIIVITYACMILVTMVMRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTENPENLGQFYNYPMSLFTTFELFLTIIDGPANYDVDLPFMYSVVYFAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLPRCLWPRTGICGREYGLGDRWYLRIEDRIDPNKHKMMRYTEAFKAHDRDNCDKSLEKLEVDRNILYKKDLSIPSLSRGMSRTNSQSGWEILRRNTFHQLHGEINHAMEEEVYDV", "length": 724, "header": "tr|A0A8V0ZQY1-1|A0A8V0ZQY1_CHICK Isoform 1 of Transient receptor potential cation channel subfamily V member 6 OS=Gallus gallus OX=9031 GN=TRPV6 PE=4 SV=1 CANONICAL=A0A8V0ZQY1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZK71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY1/entry#A0A8V0ZK71-1", "sequence": { "sequence": "MGVPLFGDSKPFYFRIWNGLSQKLQGKKSWDKHLDEIYLLQQKRICESPLLQAAKENNIPAITKLLADGTCDIYQRGAVGETALHVAALYDNVEAAVALMEAAPELVNERMTSELYEGQTALHIAAVNQNITLVKALLKRGANTCTAQATGHFFRRSSQNLLYFGNTVLHILVLQPNKTFACHMYSLILSYDQSKEGPRSLELIPNNEGLTPFKLAGVEGNTVMFQYLMQRRKHNLWSFGPLTTVLYDLTEIDSWAEDQSFLELIVSTKKREARQILDLTPVKELVSLKWNMYGRPYFCFLALFYVLYMVCFTMCCVYRPLKPRTGNKTSSRDNTVYVQKMLQESYVTYEDELRLVGELITVIGAVVILILEIPDILRVGAAKYFGQTILGGPFHIIVITYACMILVTMVMRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTENPENLGQFYNYPMSLFTTFELFLTIIDGPANYDVDLPFMYSVVYFAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLPRCLWPRTGICGREYGLGDRWYLRIEDRIDPNKHKMMRYTEAFKAHDRDNCDKSLEKLEVDRNILYKKDLSIPSLSRGMSRTNSQSGWEILRRNTFHQLHGEINHAMEEEVYDV", "length": 691, "header": "tr|A0A8V0ZK71-1|A0A8V0ZQY1_CHICK Computationally mapped isoform of Transient receptor potential cation channel subfamily V member 6 OS=Gallus gallus OX=9031 GN=TRPV6 PE=4 SV=1 CANONICAL=A0A8V0ZQY1-1" }, "locus": { "chromosome": "1", "start_pos": 77903035, "end_pos": 77874029, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052161.1", "url": "https://www.ensembl.org/id/ENSGALT00010052161.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031152.1", "url": "https://www.ensembl.org/id/ENSGALP00010031152.1" } ] } }, { "isoform_ac": "A0A8V0ZQY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY1/entry#A0A8V0ZQY1-1", "sequence": { "sequence": "MGVPLFGDSKPFYFRIWNGLSQKLQGKKSWDKHLDEIYLLQQKRICESPLLQAAKENNIPAITKLLADGTCDIYQRGAVGETALHVAALYDNVEAAVALMEAAPELVNERMTSELYEGQTALHIAAVNQNITLVKALLKRGANTCTAQATGHFFRRSSQNLLYFGEHVLSFAACVGNEEIVQLLIENGADIRAQDYLGNTVLHILVLQPNKTFACHMYSLILSYDQSKEGPRSLELIPNNEGLTPFKLAGVEGNTVMFQYLMQRRKHNLWSFGPLTTVLYDLTEIDSWAEDQSFLELIVSTKKREARQILDLTPVKELVSLKWNMYGRPYFCFLALFYVLYMVCFTMCCVYRPLKPRTGNKTSSRDNTVYVQKMLQESYVTYEDELRLVGELITVIGAVVILILEIPDILRVGAAKYFGQTILGGPFHIIVITYACMILVTMVMRLTSTTGEVVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQKMIFGDLMRFCWLMAVVILGFASAFYIIFQTENPENLGQFYNYPMSLFTTFELFLTIIDGPANYDVDLPFMYSVVYFAFAIIATLLMLNLLIAMMGDTHWRVAHERDELWRAQIVATTVMLERKLPRCLWPRTGICGREYGLGDRWYLRIEDRIDPNKHKMMRYTEAFKAHDRDNCDKSLEKLEVDRNILYKKDLSIPSLSRGMSRTNSQSGWEILRRNTFHQLHGEINHAMEEEVYDV", "length": 724, "header": "tr|A0A8V0ZQY1-1|A0A8V0ZQY1_CHICK Isoform 1 of Transient receptor potential cation channel subfamily V member 6 OS=Gallus gallus OX=9031 GN=TRPV6 PE=4 SV=1 CANONICAL=A0A8V0ZQY1-1" }, "locus": { "chromosome": "1", "start_pos": 77903035, "end_pos": 77874029, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052142.1", "url": "https://www.ensembl.org/id/ENSGALT00010052142.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031144.1", "url": "https://www.ensembl.org/id/ENSGALP00010031144.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:418307", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418307", "resource": "KEGG Pathway" }, { "id": "R-GGA-3295583", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3295583", "resource": "Reactome", "description": "TRP channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY1", "url": 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"recommended", "evidence": [ { "id": "A0A8V0ZQQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8" } ] }, { "name": "SFSWAP", "type": "synonym", "evidence": [ { "id": "XP_040540296", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040540296" } ] } ], "protein_names": [ { "name": "Splicing factor, suppressor of white-apricot homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8/entry#names_and_taxonomy" } ] }, { "name": "Splicing factor, arginine/serine-rich 8", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8/entry#names_and_taxonomy" } ] }, { "name": "Suppressor of white apricot protein homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8/entry#names_and_taxonomy" } ] }, { "name": "splicing factor, suppressor of white-apricot homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040540296", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040540296" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052587.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040540296", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040540296" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SFSWAP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8", "locus": { "chromosome": "15", "start_pos": 2807958, "end_pos": 2847468, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022958", "url": "https://www.ensembl.org/id/ENSGALG00010022958" } ] } } ], "crossref": [ { "id": "A0A8V0ZQQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQQ8", "database": 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"length": 1001, "header": "tr|A0A8V0ZQQ8-1|A0A8V0ZQQ8_CHICK Isoform 1 of Splicing factor, suppressor of white-apricot homolog OS=Gallus gallus OX=9031 GN=SFSWAP PE=4 SV=1 CANONICAL=A0A8V0ZQQ8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8/entry#A0A8V0ZKD1-1", "sequence": { "sequence": 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"tr|A0A8V0ZKD1-1|A0A8V0ZQQ8_CHICK Computationally mapped isoform of Splicing factor, suppressor of white-apricot homolog OS=Gallus gallus OX=9031 GN=SFSWAP PE=4 SV=1 CANONICAL=A0A8V0ZQQ8-1" }, "locus": { "chromosome": "15", "start_pos": 2847268, "end_pos": 2808310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055878.1", "url": "https://www.ensembl.org/id/ENSGALT00010055878.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033828.1", "url": "https://www.ensembl.org/id/ENSGALP00010033828.1" } ] } }, { "isoform_ac": "A0A8V0ZQQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8/entry#A0A8V0ZQQ8-1", "sequence": { "sequence": "MLLSGGGAAPGPPGGGGGGGGGGGNSRVELLVFGYACKLFRDDEKAQYQEQGRHLIPWMGDPKIMIDRYDGRGHLHDLSEYDAEYSTWNRDYQLSEEEARIEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGTYNAVGFRYGSDYYDPSEPTEEEEHQPAKQRETAQTENVEENEEPFVAPPGLNVPSDVELPPTAKMHAIIERTANFVCKQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYAAPSENKADEKKHTKVKSEEEDDDDDDDDGNYLHPSLFASKKSSRLEELMKPLKVVDPDHPLAALVRKAQSDNNSSTPQSTDGAAVQTSQVEYSSDSTVAAMYYSYYMLPDGTYCLAPPPPGIDVATYYNALPAGVTVSSTTGVATVPPPPGTTPPPPPDTTDSSSGLTSTTTSTSTIAPVVAIIPPPPDIQPVIDKLAEYVARNGIKFETSVRAKNDLRFEFLQPWHQYNPYYEFKKQFFLQKESSDNCQGVSSSEDVPADTTTDAPSETQLADGHAPEDGSEPIAKGAPETKKDVLPKTVSDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDEEEEEGKEGQENANSASNSTPAVTTPCVAAEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLSEAETEKVEENSFSVESVSSIPCPATAVRTLPTLDVGRTSAAERPSSKSRDPPRDEEKEKKRKKHKKRSRSRSRSPFKYHSSSKTRSRSHSKAKHSLPTAYRTVRHSRLTASTGTLSMEPSLSSSSVAAATERESYQAASTTKRFDCWRSFEGNPGKTSRSRSRSPRRRAHTPERRREERSVPTAYRISNSPGNSRKRARSKSPHEKKKKRRSRSRTKSRARSPSPAVSPGKPSTHKNSVHSNSVSPVESRESSQERSRGVSQEKDGQISSAIVSSVQSKITQDLMAKVRAMLAASKNIQTSAS", "length": 1001, "header": "tr|A0A8V0ZQQ8-1|A0A8V0ZQQ8_CHICK Isoform 1 of Splicing factor, suppressor of white-apricot homolog OS=Gallus gallus OX=9031 GN=SFSWAP PE=4 SV=1 CANONICAL=A0A8V0ZQQ8-1" }, "locus": { "chromosome": "15", "start_pos": 2847268, "end_pos": 2808310, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055881.1", "url": "https://www.ensembl.org/id/ENSGALT00010055881.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033830.1", "url": "https://www.ensembl.org/id/ENSGALP00010033830.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 416, "start_aa": "Thr", "end_pos": 416, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr416", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 623, "start_aa": "Thr", "end_pos": 623, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr623", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416802", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416802", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LYZ4-1", "protein_name": "Splicing factor, suppressor of white-apricot homolog", "gene_name": "SFSWAP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYGASGGRTKTERKSGAKEETGPGGAGGGGNRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDLSEYDAEYSTWNRDYQLSEEEARIETLCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQREKNEAENLEENEEPFIAPLGLNVPPDVELPPTAKMHAIIERTANFVCKQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAENKSEEKKKSGVSSDNEDDDDEEDGSYLHPSLFASKKCNRLEELMKPLKVVDPDHPLAALVRKAQADSPAPTPPTADGAAVQPSQVEYTTDSTVAAMYYSYYMLPDGTYCLAPPPPGVDVATYYSTLPAGVAVSSSTGVTATAPPPPGTTPPPPPTTAETSSGVTSTTITTSALAPVATIIPPPPDIQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGENAQAVSAPEETPAEPAPEKPSDAGEDSVSEDAADAGGRGVSSGKKEASSSRAVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSATNTNPAVAPPCVVVEEKRPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEVGKVEESPFSIEEAGTVPCPLLAGGRPLPTLDVKPPEGRSSRSKDPPREEERERKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHCLPSAYRTARRSRPTASPGTLSTEPCQSSSAVAAAAERDSYQAASTTSRFASWSSFEGKPGKMSRSRSRSPRRRAHSPERRREDRSVPTAYRMSNSPGVSRKRTRSRSPHEKKKKRRSRSRTKSKAGSQPASPSKQPARRHSASISPVESRGSSQERSRGVSQEKDGQISSAIVSSVQSKITQDLMAKVRAMLAASKNMQTSAS", "length": 994 }, "evidence": [ { "id": "A0A8V0ZQQ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQQ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A9J7K7U1-1", "protein_name": "Splicing factor, suppressor of white-apricot homolog", "gene_name": "Sfswap", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYGAGAGRAKPERKGGAKEEAGPGGAGTGGNRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDLSAYDAEYATWNRDYQLSEEEARVEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGNYSAVGFTYGSDYYDPSEPTEEEEPSKQREKNEAENLEENEEPFIAPLGLSVPSDVELPPTAKMHAIIERTANFVCKQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKSMKEGRYTVLAENKNEEKKKSQASLRFVAVLLPRPLKYWGYRCEPSYLVANILNSIAESGSTSDNEDEDEEEDGSYLHPSLFASKKSSRLEELMKPLKVVDPDHPLAALVRKAQADSSAPAPPTADGTPTQPSQVEYTTDSAVAAMYYSYYMLPDGTYCLAPPPPGIDVATYYSTLPAGVTVSSSPGVTTTVPPPPGTTPPPPPTTAETSSGVTSTTTTTSALAPVAIIPPPPDIQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGSSTQVASTAEEASTETAAEESSEAGEDSTPEGMAETGGRGSGKKEAGSSKSTVDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSEEDEESRECQESTSNVANPSPAAAPPCVLVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEVGKLEESAFNVEETSVMPCPLLVGGRTLPMLEVKPPERPSSRCRDPPREEEREKKKKKHKKRSRTRSRSPKYHSSSKPRSRSHSKAKHSLPSAYRTVRRSRPSASPGILSVEPCPSSSAVAAAQQESYQAASASSSFDSWSSFEGKPGKPSRSRSRSPRRRAHSPERRREDRSVPTAYRMSSSPGASRKRTRSRSPHEKKKKRRSRSRTKAKARSQSTSPSKQAAQRPSAHSAHSASISPVESRGSSQERSRGVSQEKDGQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS", "length": 1034 }, "evidence": [ { "id": "A0A8V0ZQQ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQQ8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZTQ1-1", "protein_name": "Splicing factor, suppressor of white-apricot homolog", "gene_name": "Sfswap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYGAGGGRAKAERKGGVKEEAGPGGTGTGGNRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDLSAYDAEYATWNRDYQLSEEEARVEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGNYSAVGFTYGSDYYDPSEPTEEEEPSKQREKSEAENLEENEEPFIAPLGLSVPSDVELPPTAKMHAIIERTANFVCKQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAESKSEEKKKSGPTSDNEEEDDEEDGSYLHPSLFASKKSSRLEELMKPLKVVDPDHPLAALVRKAQADSSAPAPPTADGTPAQPSQVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVATYYSTLPAGVTVSSSPGVTTTVPPPPGTTPPPPPTTAESSSGVTSTTTTTSALAPVAIIPPPPDIQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGGSTQAASTAEEAPTETAVEESSEAGEDGAPEGMAETGGRGSGKKEAGSSKSTVDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSEEDEESRECQESTSSVANPSPAAAPPSAVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPDAEVGKLEESTFGVEETGVMPCPLLVGGRTLPMLEGKPPERPSSRCRDPPREEEREKKKKKHKKRSRTRSRSPKYHSSSKPRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREDRSVPTAYRMSGSPGVSRKRTRSRSPHEKKKKRRSRSRTKAKARSQSTSPSKQAAQRPSAHSAHSASISPVESRGSSQERSRGVSQEKDGQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS", "length": 945 }, "evidence": [ { "id": "A0A8V0ZQQ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQQ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q5L3-1", "protein_name": "Splicing factor, suppressor of white-apricot homolog", "gene_name": "sfswap", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYRRGGSKKEQNNATKEQSDSSKYAELLVFGYACKLFRDDERAFYHDQGKHLIPWMGDKNIMIDRYDGRGHLHDLSEYDAGSWNHDYQLSEEEARIEALCDEERYLAMHTDLLEEEARQEEEYKRLSEALADEGTYNAVAFRYSADYYDPSQPTEEDEASKEADQEQLEEESEEPFVAPPGLLIPPDVELPATTKTHAIIERTANFVCKQGAQFEIVLKAKQAGNSQFDFLRFDHYLNPYYKHILRAMKEGRYTPASEGKQDQQQESKSDESDDDDDGDGNYLHPSLFAPKKCSRLEEIIKPLQVIDPDHPLAALVRKAQQQNNGTAALVTNAEEEHQPSAVATQAEYTSDPNVAAMYYGYCMLPDGTYCLAPPPPGIDASHYYASLPTGMMPAPPASGPPPPPGTTPLDPAVAIPSAPAVGPVTVSAPASAPLPHSAPAPPTSSSRPPQTTVVPPPVVATAAPVAAIIPPPPDIQPVIDKLAEYVARNGVKFETSVRAKNDPRFDFLQSWHQYNSYYEFKKHYFMQKEGLSGQEGSLLYGSGGDSAENSSDKQQDEGKLIKASFAPICFAIKSKENDLLPLEKNRVRLDDDSDEDAIKGDVLEGMELAIGLLEAPREVPQPPLAEEKKPVLSQEELEAKQAKQKLEDRLAAAAREKLAQASKESKERQLQAERKRKAALFLQTLRGPEAEVKRTEETTAAPEPLGSILPISGLLQHTCRIPGFDYEPLENALTRSLNNAASHVTTSTSSSSSRGPERDRDRDRDRDRDRDKRKKKHKRRSRSRSRSRSRSKSKTKHALPSAYRTFRRSRSQSRSPSRRDRRARSPDRKRDEREKESYGPSNYRLGSNPALGRQRSRSRSPHEKKKRKSSKSSHFKGSSCSPSASPNRGRAVSRVSASPSPATSPTSSLGRSRDGSQEKEKQVASTIVSSVQSKITQDLMAKVRAMLAASKGLQPNPS", "length": 958 }, "evidence": [ { "id": "A0A8V0ZQQ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQQ8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RFQ9-1", "protein_name": "Splicing factor, suppressor of white-apricot homolog", "gene_name": "SFSWAP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYGASGGRAKTERKSGVKEEAGPGGAGGGGNRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDLSEYDAEYSTWNRDYQLSEEEARIEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQREKNEAENLEENEEPFIAPLGLNVPPDVELPPTAKMHAIIERTANFVCKQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAENKSEEKKKPGVSSDNEDEDDEEDGSYLHPSLFASKKCSRLEELMKPLKVVDPDHPLAALVRKAQADSPTPTPPTTDGAAVQPSQVEYSTDSTVAAMYYSYYMLPDGTYCLAPPPPGVDVATYYSTLPAGVAVSSSAGVTATAPPPPGTTPPPPPTTAETSSGVTSTTITTSALAPVAAIIPPPPDIQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGESAQSVSAPEEAPAESAPEKPSDTGEDAVSEDVADAGGRSSSSGKKEASSTSKAVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSATNTNPAVAPPCVVVEEKRPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEVGKAEESTFNAEEASAVSCPLLAGGRPLPTLDIKPPEGPSSKSKDLSREEEREKKKKKHKKRSRTRSRSPKYHSSSSKSRSRSHSKAKHCLPSAYRTARRSRSRSRSPRRRAHSPERRREDRSVPTAYRMSNSPGVSRKRTRSRSPHEKKKKRRSRSRTKSKAGSQPASPSKQAARRHSASISPVESRGSSQERSRGVSQEKDGQISSAIVSSVQSKITQDLMAKVRAMLAASKNMQTSAS", "length": 944 }, "evidence": [ { "id": "A0A8V0ZQQ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQQ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P12297-2", "protein_name": "Protein suppressor of white apricot", "gene_name": "su(w[a])", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLPYNVRNAGGGSVGGILRRTGQGSGTGSTILGNGNSPGALGAGKVSSSLENHRQPPLELLVFGYACKIFRDDEKAREMDHGKQLIPWMGDVNLKIDRYDVRGALCELAPHEAPPGGYGNRLEYLSAEEQRAEQLCEEERYLFLYNNEEELRLRQEEDLKRLQQETSGGCFSQVGFQYDGQSAASTSIGGSSTATSQLSPNSEESELPFVLPYTLMMAPPLDMQLPETMKQHAIIEKTARFIATQGAQMEILIKAKQANNTQFDFLTQGGHLQPYYRHLLAAIKAAKFPPAPQTPLDQQNTDKEAPSADDHSEEVAGGRRNPNQVVITVPTIKYKPSANCAYTQLISKIKGVPLQAVLQEDESSNPGNSQHSGGTASPALSCRSEGHNSQGGEFTPVLLQYNGSTFTHEEESSNREQQDDNDVNGGEPPQVELLKNTSALALAQNYSSESEEEEDQVQPEKEEEKKPEPVLTFPVPKDSLRHIIDKTATYVIKNGRQFEETLRTKSVDRFSFLLPANEYYPYYLYKVTGDVDAASKEEKTRKAAAVAAALMSKKGLSFGGAAAAVSGSNLDKAPVSFSIRARDDQCPLQHTLPQEASDEETSSNAAGVEHVRPGMPDSVQRAIKQVETQLLARTAGQKGNITASPSCSSPQKEQRQAEERVKDKLAQIAREKLNGMISREKQLQLERKRKALAFLNQIKGEGAIVGSAVPVVGPNPPESAAGAATADSGDESGDSVRSIPITYFGPDDDDEVGEQRPEMRLIGSTQKDEEDDDEEDGGDLEKYNLLNDDSTNTFTSKPVLPPTAAPPPAAVLLSDDDDVQLVATTSTRSSSSRHLKTHRRSRSRSKNVRSSDSSPSSRESSRRRRQKSSRLSREPSSNPPRKSQHSSTQRKKTPKKRRRSKSRSRSKSIRRSRSISILRNNRRSRSRSPSCRNAEQRRQQDRRRTPTKKSHKRHKRRRRSSSP", "length": 963 }, "evidence": [ { "id": "A0A8V0ZQQ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQQ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q12872-1", "protein_name": "Splicing factor, suppressor of white-apricot homolog", "gene_name": "SFSWAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYGASGGRAKPERKSGAKEEAGPGGAGGGGSRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDHKILIDRYDGRGHLHDLSEYDAEYSTWNRDYQLSEEEARIEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGSYNAVGFTYGSDYYDPSEPTEEEEPSKQREKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAENKSDEKKKSGVSSDNEDDDDEEDGNYLHPSLFASKKCNRLEELMKPLKVVDPDHPLAALVRKAQADSSTPTPHNADGAPVQPSQVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSALAPVAAIIPPPPDVQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSGGKKEASSSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEGQESSSSAANTNPAVAPPCVVVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRGVSQEKEAQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS", "length": 951 }, "evidence": [ { "id": "A0A8V0ZQQ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQQ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3USH5-1", "protein_name": "Splicing factor, suppressor of white-apricot homolog", "gene_name": "Sfswap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYGAGGGRAKPERKGGVKEEAGPGGTGTGGNRVELLVFGYACKLFRDDERALAQEQGQHLIPWMGDPKILIDRYDGRGHLHDLSAYDAEYATWNRDYQLSEEEARVEALCDEERYLALHTDLLEEEARQEEEYKRLSEALAEDGNYSAVGFTYGSDYYDPSEPTEEEEPSKQREKNEAENLEENEEPFIAPLGLSVPSDVELPPTAKMHAIIERTANFVCKQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAESKNEEKKKSGPTSDNEEEDDEEDGSYLHPSLFASKKSSRLEELMKPLKVVDPDHPLAALVRKAQADSSAPAPPTADGTPAQPSQVEYTADSTVAAMYYSYYMLPDGTYCLAPPPPGIDVATYYSTLPAGVTVSSSPGVTTTVPPPPGTTPPPPPTTAEPSSGVTSTTTTTSALAPVAIIPPPPDIQPVIDKLAEYVARNGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGGSTQAASTAEEAPTETAVEESGEAGEDGAPEGMAETGGRGSGKKEAGSSKSTVDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSEEDEESRECQESTSSVANPSPAAAPPSVAVEEKKPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNPLPEAEVGKLEESTFGVEDTGVMPCPLLVGGRTLPILEGKPPERPSNRCRDPPREEEREKKKKKHKKRSRTRSRSPKYHSSSKPRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRREERSVPTAYRMSGSPGVSRKRTRSRSPHEKKKKRRSRSRTKAKARSQSTSPSKQAAQRPSAHSAHSASISPVESRGSSQERSRGVSQEKDGQISSAIVSSVQSKITQDLMAKVRAMLAASKNLQTSAS", "length": 945 }, "evidence": [ { "id": "A0A8V0ZQQ8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQQ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8" } ], "pmid": "" }, { "name": "mRNA 5'-splice site recognition", "id": "GO:0000395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000395", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": 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"Ensembl Peptide", "id": "ENSGALP00010031234.1", "url": "https://www.ensembl.org/id/ENSGALP00010031234.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, 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}, { "id": "A0A8V0ZR69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR69-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCGGCVGTEYPERGTTCLEGGSFLLNFVGCARCGRRDFVLLGNRAAGLHGDDEIITYDHLCKNCHHLIARHEYTFSVVDDYQVHPPGVRGFCCAVRSLPSSGGALSLASAHLPSQPLEGAGGEQQVGASCSAGAGPSVTGAQLRSSVAHMEAATPHSPSLFPGSLPIQQQSTGKWAPGSQWWTGCWGGGGVKCNPLRSDCNRGSGVGPSSGFLWWWREGIAWPEPPSCTVFCSRSTPCCACCAAAPRTRSASCLTTRAR", "length": 259, "header": "tr|A0A8V0ZR66-1|A0A8V0ZR66_CHICK Isoform 1 of Protein Churchill OS=Gallus gallus OX=9031 GN=CHURC1 PE=3 SV=1 CANONICAL=A0A8V0ZR66-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR66/entry#A0A8V0ZKH0-1", "sequence": { "sequence": "MCGGCVGTEYPERGTTCLEGGSFLLNFVGCARCGRRDFVLLGNRAAGLHGDDEIITYDHLCKNCHHLIARHEYTFSVVDDYQVHPPGVRGFCCAVRSLPSSGGALSLASAHLPSQPLEGAGGVHHAVPAVRPRRGLGQHPA", "length": 141, "header": "tr|A0A8V0ZKH0-1|A0A8V0ZR66_CHICK Computationally mapped isoform of Protein Churchill OS=Gallus gallus OX=9031 GN=CHURC1 PE=3 SV=1 CANONICAL=A0A8V0ZR66-1" }, "locus": { "chromosome": "5", "start_pos": 533030, "end_pos": 531493, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052310.1", "url": "https://www.ensembl.org/id/ENSGALT00010052310.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031251.1", "url": "https://www.ensembl.org/id/ENSGALP00010031251.1" } ] } }, { "isoform_ac": "A0A8V0ZR66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR66/entry#A0A8V0ZR66-1", "sequence": { "sequence": "MCGGCVGTEYPERGTTCLEGGSFLLNFVGCARCGRRDFVLLGNRAAGLHGDDEIITYDHLCKNCHHLIARHEYTFSVVDDYQVHPPGVRGFCCAVRSLPSSGGALSLASAHLPSQPLEGAGGEQQVGASCSAGAGPSVTGAQLRSSVAHMEAATPHSPSLFPGSLPIQQQSTGKWAPGSQWWTGCWGGGGVKCNPLRSDCNRGSGVGPSSGFLWWWREGIAWPEPPSCTVFCSRSTPCCACCAAAPRTRSASCLTTRAR", "length": 259, "header": "tr|A0A8V0ZR66-1|A0A8V0ZR66_CHICK Isoform 1 of Protein Churchill OS=Gallus gallus OX=9031 GN=CHURC1 PE=3 SV=1 CANONICAL=A0A8V0ZR66-1" }, "locus": { "chromosome": "5", "start_pos": 533030, "end_pos": 531476, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052306.1", "url": "https://www.ensembl.org/id/ENSGALT00010052306.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031249.1", "url": "https://www.ensembl.org/id/ENSGALP00010031249.1" } ] } }, { "isoform_ac": "A0A8V0ZR69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR66/entry#A0A8V0ZR69-1", "sequence": { "sequence": "RWVTRIGLRFPQGTTCLEGGSFLLNFVGCARCGRRDFVLLGNRAAGLHGDDEIITYDHLCKNCHHLIARHEYTFSVVDDYQEYTMLCLLCGRAEDSVSILPDDPRQMTPLF", "length": 111, "header": "tr|A0A8V0ZR69-1|A0A8V0ZR69_CHICK Computationally mapped isoform of Protein Churchill OS=Gallus gallus OX=9031 GN=CHURC1 PE=3 SV=1 CANONICAL=A0A8V0ZR66-1" }, "locus": { "chromosome": "5", "start_pos": 533460, "end_pos": 531462, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052315.1", "url": "https://www.ensembl.org/id/ENSGALT00010052315.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031254.1", "url": "https://www.ensembl.org/id/ENSGALP00010031254.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR66" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR66", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR66" } ], "pmid": "" }, { "name": "fibroblast growth factor receptor signaling pathway", "id": "GO:0008543", "url": 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"database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR609508-1" }, { "id": "A0A8V0ZKH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH0#function" }, { "id": "A0A8V0ZKH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH0" } ], "binding_site_uniprot": 66, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 66, "end_pos": 66, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR69#function" }, { "id": "A0A8V0ZR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR69" }, { "id": "PIRSR609508-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR609508-1" } ], "binding_site_uniprot": 70, "amino_acid": "Arg", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 70, "end_pos": 70, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZR66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR66#function" }, { "id": "A0A8V0ZR66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR66" }, { "id": "PIRSR609508-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR609508-1" }, { "id": "A0A8V0ZKH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH0#function" }, { "id": "A0A8V0ZKH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKH0" } ], "binding_site_uniprot": 71, "amino_acid": "His", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "3", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 71, "end_pos": 71, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR69#function" }, { "id": "A0A8V0ZR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR69" }, { "id": "PIRSR609508-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR609508-1" } ], "binding_site_uniprot": 87, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 87, "end_pos": 87, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR69#function" }, { "id": "A0A8V0ZR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR69" }, { "id": "PIRSR609508-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR609508-1" } ], "binding_site_uniprot": 90, "amino_acid": "Gly", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 90, "end_pos": 90, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRA6-1", "uniprot_ac": "A0A8V0ZRA6", "uniprot_id": "A0A8V0ZRA6_CHICK", "mass": { "chemical_mass": 52418.0, "monoisotopic_mass": 52418.0 }, "refseq": { "ac": "XP_423856", "name": "tetratricopeptide repeat protein 38", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423856" }, "gene_names": [ { "name": "LOC426193", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA6" } ] }, { "name": "LOC426193", "type": "synonym", "evidence": [ { "id": "XP_423856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423856" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 38", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA6/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 38", "type": "synonym", "evidence": [ { "id": "XP_423856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423856" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_423856.6. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_423856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423856" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC426193", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA6", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZRA6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRA6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05804", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05804", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426193", "url": "https://www.ncbi.nlm.nih.gov/gene/426193", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426193", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426193", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DLCERHA", "url": "https://omabrowser.org/oma/group/DLCERHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRA6", "url": "https://www.orthodb.org/?gene=A0A8V0ZRA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16263", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16263", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16263:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16263:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_423856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_423856", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZKZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRA6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPLRDCKAWQDSGLGLSTASNEACKLFDAVLSQYATWRNDENLGGIEGCLSKLKAADPNFVMGHVIANGLELIGAGSSVRLNKDLGSALKTMTTLSRSQPLTEREKLHVLALDMFARGQLPKACDVWEQILQNHPTDLLALRFSHDTYFYLGYQIQMRDSIARVFPFWTPEVPLSSYVKGYYAFGLMESNFFDRAEELAREALDINRTDAWSVHTIAHVNEMKAEVEKGLAFMKETEDNWKDSDMLITHNYWHWALGFIEKGEYEAALTIYDNHIAPRLLSGRSMLGIVDSSSMLYRLHLEGVKLGDRWDDVLKRAKKHTKDHVLLFNDAHVLMSSLGAKDQKTTDELLTTLQELAKDPGEDHELSLAPSVGLPLCQALVEFENGNCDKAVDLLYPIRYQLIHLGGSNAQRDIFSQLLIHAALNCKSQAKQNLAKCLLRERDVMRPNSPMTERLIRRAAAVHSVA", "length": 466, "header": "tr|A0A8V0ZRA6-1|A0A8V0ZRA6_CHICK Isoform 1 of Tetratricopeptide repeat protein 38 OS=Gallus gallus OX=9031 GN=LOC426193 PE=1 SV=1 CANONICAL=A0A8V0ZRA6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZKZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA6/entry#A0A8V0ZKZ3-1", "sequence": { "sequence": "MRIYATWRNDENLGGIEGCLSKLKAADPNFVMGHVIANGLELIGAGSSVRLNKDLGSALKTMTTLSRSQPLTEREKLHVLALDMFARGQLPKACDVWEQILQNHPTDLLALRFSHDTYFYLGYQIQMRDSIARVFPFWTPEVPLSSYVKGYYAFGLMESNFFDRAEELAREALDINRTDAWSVHTIAHVNEMKAEVEKGLAFMKETEDNWKDSDMLITHNYWHWALGFIEKGEYEAALTIYDNHIAPRLLSGRSMLGIVDSSSMLYRLHLEGVKLGDRWDDVLKRAKKHTKDHVLLFNDAHVLMSSLGAKDQKTTDELLTTLQELAKDPGEDHELSLAPSVGLPLCQALVEFENGNCDKAVDLLYPIRYQLIHLGGSNAQRDIFSQLLIHAALNCKSQAKQNLAKCLLRERDVMRPNSPMTERLIRRAAAVHSVA", "length": 435, "header": "tr|A0A8V0ZKZ3-1|A0A8V0ZRA6_CHICK Computationally mapped isoform of Tetratricopeptide repeat protein 38 OS=Gallus gallus OX=9031 GN=LOC426193 PE=1 SV=1 CANONICAL=A0A8V0ZRA6-1" }, "locus": { "chromosome": "1", "start_pos": 71440128, "end_pos": 71425204, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056233.1", "url": "https://www.ensembl.org/id/ENSGALT00010056233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034039.1", "url": "https://www.ensembl.org/id/ENSGALP00010034039.1" } ] } }, { "isoform_ac": "A0A8V0ZRA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA6/entry#A0A8V0ZRA6-1", "sequence": { "sequence": "MAPLRDCKAWQDSGLGLSTASNEACKLFDAVLSQYATWRNDENLGGIEGCLSKLKAADPNFVMGHVIANGLELIGAGSSVRLNKDLGSALKTMTTLSRSQPLTEREKLHVLALDMFARGQLPKACDVWEQILQNHPTDLLALRFSHDTYFYLGYQIQMRDSIARVFPFWTPEVPLSSYVKGYYAFGLMESNFFDRAEELAREALDINRTDAWSVHTIAHVNEMKAEVEKGLAFMKETEDNWKDSDMLITHNYWHWALGFIEKGEYEAALTIYDNHIAPRLLSGRSMLGIVDSSSMLYRLHLEGVKLGDRWDDVLKRAKKHTKDHVLLFNDAHVLMSSLGAKDQKTTDELLTTLQELAKDPGEDHELSLAPSVGLPLCQALVEFENGNCDKAVDLLYPIRYQLIHLGGSNAQRDIFSQLLIHAALNCKSQAKQNLAKCLLRERDVMRPNSPMTERLIRRAAAVHSVA", "length": 466, "header": "tr|A0A8V0ZRA6-1|A0A8V0ZRA6_CHICK Isoform 1 of Tetratricopeptide repeat protein 38 OS=Gallus gallus OX=9031 GN=LOC426193 PE=1 SV=1 CANONICAL=A0A8V0ZRA6-1" }, "locus": { "chromosome": "1", "start_pos": 71440128, "end_pos": 71422586, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056237.1", "url": "https://www.ensembl.org/id/ENSGALT00010056237.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034041.1", "url": "https://www.ensembl.org/id/ENSGALP00010034041.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426193", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426193", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9LFX3-1", "protein_name": "Tetratricopeptide repeat (TPR)-like superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEKTVRCVRWGYEVNTSSDACIDAINSYFQQVLSYGRKRKVILEAPLYDKDCVLGSILAAHFLSSSDPSRANSYVEAAASNLEQSTPYEKAVYEAVTYLISEDRDDDLAFEMHTKLLKRFPKDLASLKRAQLLSFYMGQPDPFLGLVQQVLPANQEESYIHGLLAFPLLELGRMEEAAAASRKGYEINKEDAWAHHCLCHVLQHECRFKEAVEFMEALAGTWPSCSSFMYTHNWWHVALCYLEGGSPMSKVEEIYDHHIWKELEKDDAVPPEVYLNALGLLIRLDVRDALDGFEDRLKNLAVRLTNQANWYLEWHLDILIVWALAKVGETSRAHELLEGLKFRLSKKNKKKQQVMQKGIQLGEAVYEYARGNYEKALELLGSEFNAIGYKIVGASDEQIDVFNEMWCQLLLKTGQSSTAKEVIRERIKARDGIPFMWRLLEKSYSMEGNAEAESSARERAKKLESCYF", "length": 468 }, "evidence": [ { "id": "A0A8V0ZRA6", "url": "https://omabrowser.org/oma/group/A0A8V0ZRA6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 207, "end_pos": 209 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRG1-1", "uniprot_ac": "A0A8V0ZRG1", "uniprot_id": "A0A8V0ZRG1_CHICK", "mass": { "chemical_mass": 81639.0, "monoisotopic_mass": 81639.0 }, "refseq": { "ac": "XP_015146086", "name": "zinc finger CCCH-type antiviral protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146086" }, "gene_names": [ { "name": "ZC3HAV1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" } ] }, { "name": "ZAP", "type": "synonym", "evidence": [ { "id": "XP_015146086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146086" } ] }, { "name": "ZC3HAV1", "type": "synonym", "evidence": [ { "id": "XP_015146086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146086" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH-type containing, antiviral 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCCH-type antiviral protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015146086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146086" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052532.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015146086.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146086" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZC3HAV1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1", "locus": { "chromosome": "1", "start_pos": 71443183, "end_pos": 71482037, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023107", "url": "https://www.ensembl.org/id/ENSGALG00010023107" } ] } } ], "crossref": [ { "id": "A0A8V0ZRG1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRG1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01439", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01439", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426315", "url": "https://www.ncbi.nlm.nih.gov/gene/426315", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051712", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051712", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KWKSPTS", "url": "https://omabrowser.org/oma/group/KWKSPTS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL52", "url": "https://www.orthodb.org/?gene=A0A8V0ZL52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRG1", "url": "https://www.orthodb.org/?gene=A0A8V0ZRG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUF0", "url": "https://www.orthodb.org/?gene=A0A8V0ZUF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45740:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45740:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18606", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18606", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23466", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23466", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146086", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUF0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDPVVCSFLTKTLCAEGGRLGLAELQQHVGLSAQQLQETLQAAGPERFLLLTGAGGAPEVLALTAVRICMRKQCEGCERLHLCKLHLMGRCSLRHRVCKYSHDITSAENKKVLKTHELSGLSENELRILLLQNDPFLLPDACQFYNNRVNTCSQRDDCNKLHICRYFLHGGCKFFPCKKSHNFLDSCALRLLKNGGIDEKMASNIQKVYDHKHVELHKREKPNGPSYKPRQTSEEDRTNKSSKEQKPSFETPEVSTVHAPPSEAVLFSQPSHADRSSNKTHQSEREFLTGTRSKVEGKKDDSSVNSSKDNKDKSDEICLFNVWKYCKHNEKCTSVHYHLPYRWQVYNGITWNDLSMMEEIEKAYCDPKNSSAADKGINFQTMTLSSSLIRRLSTPSSVVNPTFVLTTKWIWYWKNDHGQWTEYGTQGEQGIVNSPSSDILENLYLADPDTTIQFQAGLYYYQLNFKEMIQINTSSKTKRKVCRRPKFVSYEEVQKIKERGQRDSIPSQACPPHWDQSALPDFGYKEVEISTISSEYQEIKKQFEQTMKSCNIIKILRIQNPSLWKVFQWQKEQMKRQSGGKEVKERLLFHGTMGCLLEDICSHNFDWRVCGSNGNLYGKGSYFASDASYSHGYCQSAGKSTVMFMARVLVGDYAQGKEHYVRPPAKLVGGFQFYDSCVDDVANPSIFVIFEKNQIYPEYLIEYKDVQKKCIVC", "length": 714, "header": "tr|A0A8V0ZRG1-1|A0A8V0ZRG1_CHICK Isoform 1 of Zinc finger CCCH-type containing, antiviral 1 OS=Gallus gallus OX=9031 GN=ZC3HAV1 PE=1 SV=1 CANONICAL=A0A8V0ZRG1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZL52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1/entry#A0A8V0ZL52-1", "sequence": { "sequence": "MGDPVVCSFLTKTLCAEGGRLGLAELQQHVGLSAQQLQETLQAAGPERFLLLTGAGGAPEVLALTAVRICMRKQCEGCERLHLCKLHLMGRCSLRHRVCKYSHDITSAENKKVLKTHELSGLSENELRILLLQNDPFLLPDACQFYNNRVNTCSQRDDCNKLHICRYFLHGGCKFFPCKKSHNFLDSCALRLLKNGGIDEKMASNIQKVYDHKHVELHKREKPNGPSYKPRQTSEEDRTNKSSKEQKPSFETPEVSTVHAPPSEVLFSQPSHADRSSNKTHQSEREFLTGTRSKVEGKKDDSSVNSSKDNKDKSDEICLFNVWKYCKHNEKCTSVHYHLPYRWQVYNGITWNDLSMMEEIEKAYCDPKNSSAADKGINFQTMTLSSSLIRRLSTPSSVVNPTFVLTTKWIWYWKNDHGQWTEYGTQALYNCSSGDISDNKYAFFVNDCQMIQINTSSKTKRKVCRRPKFVSYEEVQKIKERGQRDSIPSQACPPHWDQSALPDFGYKEVEISTISSEYQEIKKQFEQTMKSCNIIKILRIQNPSLWKVFQWQKEQMKRQSGGKEVKERLLFHGTMGCLLEDICSHNFDWRVCGSNGNLYGKGSYFASDASYSHGYCQSAGKSTVMFMARVLVGDYAQGKEHYVRPPAKLVGGFQFYDSCVDDVANPSIFVIFEKNQIYPEYLIEYKDVQKKCIVC", "length": 695, "header": "tr|A0A8V0ZL52-1|A0A8V0ZRG1_CHICK Computationally mapped isoform of Zinc finger CCCH-type containing, antiviral 1 OS=Gallus gallus OX=9031 GN=ZC3HAV1 PE=1 SV=1 CANONICAL=A0A8V0ZRG1-1" }, "locus": { "chromosome": "1", "start_pos": 71481989, "end_pos": 71457584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056317.1", "url": "https://www.ensembl.org/id/ENSGALT00010056317.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034090.1", "url": "https://www.ensembl.org/id/ENSGALP00010034090.1" } ] } }, { "isoform_ac": "A0A8V0ZRG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1/entry#A0A8V0ZRG1-1", "sequence": { "sequence": "MGDPVVCSFLTKTLCAEGGRLGLAELQQHVGLSAQQLQETLQAAGPERFLLLTGAGGAPEVLALTAVRICMRKQCEGCERLHLCKLHLMGRCSLRHRVCKYSHDITSAENKKVLKTHELSGLSENELRILLLQNDPFLLPDACQFYNNRVNTCSQRDDCNKLHICRYFLHGGCKFFPCKKSHNFLDSCALRLLKNGGIDEKMASNIQKVYDHKHVELHKREKPNGPSYKPRQTSEEDRTNKSSKEQKPSFETPEVSTVHAPPSEAVLFSQPSHADRSSNKTHQSEREFLTGTRSKVEGKKDDSSVNSSKDNKDKSDEICLFNVWKYCKHNEKCTSVHYHLPYRWQVYNGITWNDLSMMEEIEKAYCDPKNSSAADKGINFQTMTLSSSLIRRLSTPSSVVNPTFVLTTKWIWYWKNDHGQWTEYGTQGEQGIVNSPSSDILENLYLADPDTTIQFQAGLYYYQLNFKEMIQINTSSKTKRKVCRRPKFVSYEEVQKIKERGQRDSIPSQACPPHWDQSALPDFGYKEVEISTISSEYQEIKKQFEQTMKSCNIIKILRIQNPSLWKVFQWQKEQMKRQSGGKEVKERLLFHGTMGCLLEDICSHNFDWRVCGSNGNLYGKGSYFASDASYSHGYCQSAGKSTVMFMARVLVGDYAQGKEHYVRPPAKLVGGFQFYDSCVDDVANPSIFVIFEKNQIYPEYLIEYKDVQKKCIVC", "length": 714, "header": "tr|A0A8V0ZRG1-1|A0A8V0ZRG1_CHICK Isoform 1 of Zinc finger CCCH-type containing, antiviral 1 OS=Gallus gallus OX=9031 GN=ZC3HAV1 PE=1 SV=1 CANONICAL=A0A8V0ZRG1-1" }, "locus": { "chromosome": "1", "start_pos": 71481989, "end_pos": 71457584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056325.1", "url": "https://www.ensembl.org/id/ENSGALT00010056325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034097.1", "url": "https://www.ensembl.org/id/ENSGALP00010034097.1" } ] } }, { "isoform_ac": "A0A8V0ZUF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1/entry#A0A8V0ZUF0-1", "sequence": { "sequence": "MGDPVVCSFLTKTLCAEGGRLGLAELQQHVGLSAQQLQETLQAAGPERFLLLTGAGGAPEVLALTAVRICMRKQCEGCERLHLCKLHLMGRCSLRHRVCKYSHDITSAENKKVLKTHELSGLSENELRILLLQNDPFLLPDACQFYNNRVNTCSQRDDCNKLHICRYFLHGGCKFFPCKKSHNFLDSCALRLLKNGGIDEKMASNIQKVYDHKHVELHKREKPNGPSYKPRQTSEEDRTNKSSKEQKPSFETPEVSTVHAPPSEGKKDDSSVNSSKDNKDKSDEICLFNVWKYCKHNEKCTSVHYHLPYRWQVYNGITWNDLSMMEEIEKAYCDPKNSSAADKGINFQTMTLSSSLIRRLSTPSSVVNPTFVLTTKWIWYWKNDHGQWTEYGTQGEQGIVNSPSSDILENLYLADPDTTIQFQAGLYYYQLNFKEMIQINTSSKTKRKVCRRPKFVSYEEVQKIKERGQRDSIPSQACPPHWDQSALPDFGYKEVEISTISSEYQEIKKQFEQTMKSCNIIKILRIQNPSLWKVFQWQKEQMKRQSGGKEVKERLLFHGTMGCLLEDICSHNFDWRVCGSNGNLYGKGSYFASDASYSHGYCQSAGKSTVMFMARVLVGDYAQGKEHYVRPPAKLVGGFQFYDSCVDDVANPSIFVIFEKNQIYPEYLIEYKDVQKKCIVC", "length": 681, "header": "tr|A0A8V0ZUF0-1|A0A8V0ZRG1_CHICK Computationally mapped isoform of Zinc finger CCCH-type containing, antiviral 1 OS=Gallus gallus OX=9031 GN=ZC3HAV1 PE=1 SV=1 CANONICAL=A0A8V0ZRG1-1" }, "locus": { "chromosome": "1", "start_pos": 71481989, "end_pos": 71457584, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056308.1", "url": "https://www.ensembl.org/id/ENSGALT00010056308.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034083.1", "url": "https://www.ensembl.org/id/ENSGALP00010034083.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZZJ3-1", "protein_name": "Zinc finger CCCH-type containing, antiviral 1", "gene_name": "ZC3HAV1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADPGVCCFITKILCTHGGRMALEELLQKVKLSEAQLCEVLTTAGPDRFVLLETGGKAGVTRSVVATTRVRVCRRKYCNRQCGNLHLCKLNLLGRCHYSQSERNLCKYSHEVLSDENFRVLNSHELSGLNKEELAVLLVQSDPFFMPEICKNYKGEGGRQICNQQPPCERLHVCEHFTRGNCSYSNCFRSHNLMDRKVLAVMREHGLSSSVVQNIQDICNSRHRRNKPSGARAPSSHRRDRGRSKSRERLCQDSVEFLPSASAAARVSRTPSPDSAGRHSSPDDGLVEHLATKFKGLGSHDCPQLSSVSSAATSQGGTGPRGGSQSFLENGSPESLLLVNCGGSIFSLASPPAPNWKGPTSWQNNKDPSRESSFSPNQAVTFSPLGSPQTPQATSTRKSPTLFSSDFVNLEGRSGNQDGQPFQLFHNNVDAVATDVASRKSLSYKSATSRQREKSLPRSPDAGAAHGLLQPAGKVAEDAAAAAFGNGSAPDARSTASSMMDDHGSNEICLDHLDKGCQLKNCSKVHFHLPYRWQMLSANTWMDLSLMENVEEAFCDPKVSVLSIGNYKLNFQEMTCDYNPIRRLSTPSSVTRPPGTVFTTKWVWYWKSGPNTWVRYGEKKDNQISNIDSAYLESFFLSCPRGIVPFQAGSQNFELSFPGMIQTNVASKVQKDVVRRPTFVSHWDVEQMKRGMGPPQVQPQLEPPAPTFLPQWDTHFSASNGYKLLEIHNYTPEYVEVSGRFKASMKNFKIDKIKKIQNTKLLNAFERKKHEVKVERILFCVKRRADVESICANNFDSDGTHDTKYGKGIYFTKDAISSHKDCPYDSKNVAMFVVRVLVGNFVEGHPYFTSPPLGFNSCVDTRLNPSVFVIFEKDQIYPEYLIEYTETDKPCVIS", "length": 894 }, "evidence": [ { "id": "A0A8V0ZRG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRG1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BCF8-1", "protein_name": "Zinc finger CCCH-type containing, antiviral 1", "gene_name": "ZC3HAV1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MADPGVCCFITKILCAHGGRMALEELLHEMQLSEEQLCEVLKEAGPDRFVVLEMGGKEGVTRSVVATTRARVCRRKYCNKPCGNLHLCKLNLLGRCHYSQSERNLCKYSHEVLSEDNFRVLTNHGLSGLNQEELAVLLLQSDPFFMPEICKNYKGEGGRQICNQQPPCERLHICEHFTRGNCGYANCFRSHNLMDRRVLAVMREHGLSSSVVQNIQDICNSRHRQKKPSAWKAPPPHRRDLAFRGRSKSRDRGSEEFLPAASASAQRSCSPSPEPPGHRGSVASDGPVEDLARQFSHLGSQECPPPASNPSAAVVLGGTPQGGGNQRLAENGSAKDLFYGNHSHAPLTFDLKPAFNWKGPASWQNDQDTGKKSWLPSSPVFSSSPGSPQTPETRKTTAVLSSDHVNAERRSGNQDGQHFPLFADKADGMAVDTTSTRRANYQTPSSRQREKSLPRNPDTGTPRSHLPTAGQMTGDGAAAFVNDSVPNVASTISSTMNEHSSNEICLDHLYKSCQLKSCNKVHFHLPYRWQMLLANSWVDLPFMEDIEKAFCDPKNCSVSVRTYNINFQKMICDFNPVRRISTPSSVTQPPSSLLTTKWIWYWRNGTKWVPYGEKKDNEQISSIDSSYLESLFLSCPRGIVPFQAGSRNYELSFQGMIQTNIASKTQKDVIRRPTFVSYWDVEQVKRRQDPQQGQTSSEPFINIYLPQPDTSVPGSNGFELLEIPSNTPEYAKVSDHFKASMRNFKIEKIKKVQNAQLLEAFKSKKNEMKREEQILFCATERSNVASICKNNFDWLLHGSHDTKYGKGNYFTKDAFSSHKNCPFDSRNIVMFVARVLVGNFIEGHTSYRSPPLQYDSCVDTRLNPSVFVIFQKDQIYPEYVIEYTEPERSEKPCLIS", "length": 896 }, "evidence": [ { "id": "A0A8V0ZRG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRG1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HH79-1", "protein_name": "Zinc finger CCCH-type antiviral protein 1 isoform X1", "gene_name": "Zc3hav1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADPGVCCFITKILCAHGGRMTLEELLAEIALPEAQLRELLEAAGPDRFVQLEIVGQTGVTRSVVATTRARVCRRKYCERPCDSLHLCKLNLLGRCHYSHSQRNLCKYSHEVLSEQNFQVLKNHELSGLNQEELAVLLVQSDPFFMPEICKSYKGEGRKQICGQPQPCERLHICEHFTRGNCSYLNCLRSHNLMDRKVLAIMKEHGLSSDVVQNIQDICNSKHSRRNPPAMRAPQPHRRGRARGRSKSRDRFFQNSLEFLPTVSPAESGPPSPDATSCKGSLEDVSADVTQKFKYLGTQDCAQLSSVSPKAAGLRGAGLKFSENGDPGGLFSRSCSDSSSNLAASGFHLDVTQTLEAMAKKTDKLSGYHMDVKNRSKAHDKQHVPFFDSCAGGAKMEGTASGILGNRATANGLGEILPSNHRKSAGNLLDLQITSRVADSIADSGQDMAFLGGKYGGNTVWASKSTHSDPNGSSQIMNKTPDVSKSSATGFGVKAAVTGRKEAMSFGGQSLRSQVLAMPEEITAAVPASRLPQTPPPSSSHRVAASEILGKNSTHATVSPVCKPSRRTSDSEYPLFSIASSTSPRMDDHGPKEICQDHLYKGCHQSNCNKSHFHLPYRWQLFIDNSWVDFQDMEDIERAYCDPQTESVMIGEYQINFQKMTCDYFPIRRLSTPSFDAQSVNSVFSTTWLWYWKDEFNKYVQYGDENKSHLSSNISSSYLESFFQSCPRGVLPFQAGSQNYELSFQGMIQTNIASKTQRRVVRRPVFVAWKDVERRRRGADRQPVMPAVEALTLDSPPLRDTGTFPFPSNRYELVELDSQDVEYATISELFKASMKYFKIVSIKRIWNQDLWETFERKKLMMKNDNEMLLFHATCRVHVDYICRNNFDWIINDSRETKYGKGNYFAKEAMYSHKNCSYEAKNIVMLVARVLAGNSIEGNMRYSSAPALYDSCVDSRLNPSVFVIFQKEQIYPAYVIEYTELEKEKACIIS", "length": 989 }, "evidence": [ { "id": "A0A8V0ZRG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRG1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q7Z2W4-1", "protein_name": "Zinc finger CCCH-type antiviral protein 1", "gene_name": "ZC3HAV1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADPEVCCFITKILCAHGGRMALDALLQEIALSEPQLCEVLQVAGPDRFVVLETGGEAGITRSVVATTRARVCRRKYCQRPCDNLHLCKLNLLGRCNYSQSERNLCKYSHEVLSEENFKVLKNHELSGLNKEELAVLLLQSDPFFMPEICKSYKGEGRQQICNQQPPCSRLHICDHFTRGNCRFPNCLRSHNLMDRKVLAIMREHGLNPDVVQNIQDICNSKHMQKNPPGPRAPSSHRRNMAYRARSKSRDRFFQGSQEFLASASASAERSCTPSPDQISHRASLEDAPVDDLTRKFTYLGSQDRARPPSGSSKATDLGGTSQAGTSQRFLENGSQEDLLHGNPGSTYLASNSTSAPNWKSLTSWTNDQGARRKTVFSPTLPAARSSLGSLQTPEAVTTRKGTGLLSSDYRIINGKSGTQDIQPGPLFNNNADGVATDITSTRSLNYKSTSSGHREISSPRIQDAGPASRDVQATGRIADDADPRVALVNDSLSDVTSTTSSRVDDHDSEEICLDHLCKGCPLNGSCSKVHFHLPYRWQMLIGKTWTDFEHMETIEKGYCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPANSVFTTKWIWYWKNESGTWIQYGEEKDKRKNSNVDSSYLESLYQSCPRGVVPFQAGSRNYELSFQGMIQTNIASKTQKDVIRRPTFVPQWYVQQMKRGPDHQPAKTSSVSLTATFRPQEDFCFLSSKKYKLSEIHHLHPEYVRVSEHFKASMKNFKIEKIKKIENSELLDKFTWKKSQMKEEGKLLFYATSRAYVESICSNNFDSFLHETHENKYGKGIYFAKDAIYSHKNCPYDAKNVVMFVAQVLVGKFTEGNITYTSPPPQFDSCVDTRSNPSVFVIFQKDQVYPQYVIEYTEDKACVIS", "length": 902 }, "evidence": [ { "id": "A0A8V0ZRG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRG1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K3Y6-1", "protein_name": "Zinc finger CCCH-type antiviral protein 1", "gene_name": "Zc3hav1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADPGVCCFITKILCAHGGRMTLEELLGEIRLPEAQLYELLETAGPDRFVLLETGGQAGITRSVVATTRARVCRRKYCQRPCDSLHLCKLNLLGRCHYAQSQRNLCKYSHDVLSEQNFQILKNHELSGLNQEELACLLVQSDPFFLPEICKSYKGEGRKQTCGQPQPCERLHICEHFTRGNCSYLNCLRSHNLMDRKVLTIMREHGLSPDVVQNIQDICNNKHARRNPPGTRAAHPHRRGGAHRDRSKSRDRFLHNSLEFLSPVVSPLGSGPPSPDVTSCKDSLEDVSVDVTQKFKYLGTHDRAQLSPVSSKAAGVQGPSQMRASQEFSEDGNLDDIFSRNRSDSSSSRASAAKVAQRNEAVAMKMGMEVKGKKEAPDIDRVPFLNSYIDGVTMEKASVSGIPGKKFTANDLENLLLLNDTWKNVAKPQDLQTTGRITDSGQDKAFLQNKYGGNPVWASASTHNAPNGSSQIMDETPNVSKSSTSGFAIKPAIAGGKEAVYSGVQSPRSQVLAVPGEATTPVQSNRLPQSPLSSSSHRAAASGSPGKNSTHTSVSPAIESSRMTSDPDEYLLRYILNPLFRMDNHGPKEICQDHLYKGCQQSHCDRSHFHLPYRWQMFVYTTWRDFQDMESIEQAYCDPHVELILIENHQINFQKMTCDSYPIRRLSTPSYEEKPLSAVFATKWIWYWKNEFNEYIQYGNESPGHTSSDINSAYLESFFQSCPRGVLPFQAGSQKYELSFQGMIQTNIASKTQRHVVRRPVFVSSNDVEQKRRGPE", "length": 776 }, "evidence": [ { "id": "A0A8V0ZRG1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRG1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "response to virus", "id": "GO:0009615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" } ], "pmid": "" }, { "name": "positive regulation of RIG-I signaling pathway", "id": "GO:1900246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" } ], "pmid": "" }, { "name": "positive regulation of mRNA catabolic process", "id": "GO:0061014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061014", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 142, "end_pos": 166, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZRG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" }, { "id": "PS51059", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PARP catalytic", "eco_id": "ECO_0000259", "start_pos": 511, "end_pos": 714, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZRG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG1" }, { "id": "PS50918", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50918" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WWE", "eco_id": "ECO_0000259", "start_pos": 398, "end_pos": 484, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 240, "end_pos": 242 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 473, "end_pos": 475 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRF8-1", "uniprot_ac": "A0A8V0ZRF8", "uniprot_id": "A0A8V0ZRF8_CHICK", "mass": { "chemical_mass": 85096.0, "monoisotopic_mass": 85096.0 }, "refseq": { "ac": "XP_004949785", "name": "LIM domain and actin-binding protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949785" }, "gene_names": [ { "name": "LIMA1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ] }, { "name": "LIMA1", "type": "synonym", "evidence": [ { "id": "XP_004949785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949785" } ] } ], "protein_names": [ { "name": "LIM domain and actin binding 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8/entry#names_and_taxonomy" } ] }, { "name": "LIM domain and actin-binding protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004949785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949785" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004949785.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004949785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949785" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LIMA1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8", "locus": { "chromosome": "34", "start_pos": 430656, "end_pos": 406106, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023110", "url": "https://www.ensembl.org/id/ENSGALG00010023110" } ] } } ], "crossref": [ { "id": "A0A8V0ZRF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09485", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09485", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426878", "url": "https://www.ncbi.nlm.nih.gov/gene/426878", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426878", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426878", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQQVFHV", "url": "https://omabrowser.org/oma/group/NQQVFHV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL56", "url": "https://www.orthodb.org/?gene=A0A8V0ZL56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRF8", "url": "https://www.orthodb.org/?gene=A0A8V0ZRF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUG0", "url": "https://www.orthodb.org/?gene=A0A8V0ZUG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24206", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24206", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004949785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004949785", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUG0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPSPFNRRQWTSQSLKITAKELSLVNKNKSSALAERFSRYQKAAEEATAEKKRNSTENLPPHFKRGNLSVLKKKWENPVPGTEPRKETLRSSCAEVRHRVASPELGVGSSLAFSSDTEQIPAAGTASHAQASSGTPGQLQSPGVDSRKSQSHSPESGKMENYLRESREVEKPEASENAESSGKIEKYSVPLNKLKMMFEKGEAAQPKVARDQRKTAIGRRISENSFSSEDLDVGQGEKSHSASDASPALSPDKVETKKSLEMPRLTETSIKDRLAKYQAAVSKQGSSTGLVTTNEIQASESELKNYKSEQKENMPPSFEDCISYQDGEKVSVGENSLSFHSSLSEDGNVGQNLESETEVQKPVSTKQQNFGSKSLGQTDASLPKTVKKFQLPAKETCVGCQKTVYPMERLLANQQVFHISCFRCSYCNSKLSLGTYASLRGNIYCKPHFNQLFKAKGNYDEGFGHKQHKELWSSKTECEESLEKTLHGVNATESPQNPGVEDAPIAKVGVLAATMEAKASALPEREEKPAETKKLRIAWPPPSDQSTQGSTLDEGIKVLKPKWPPEEESSKPDVLEDVDLDLKKLRRSSSLKERSRPFTVAASFRTVSVKGHKTDNSSSPSKAERDMLKRSEELEREVVVDKKHKEKIENRNMQNAEEKSVEEERELPGIKTAEHNFVENGQESAETDEEEHAVEEQQTPSEEFLEPNSPKHSSLSNVTAKESSPDQNRKSQDVGFWEGEDMEDLSVEEQIKRNRYYEDDDEE", "length": 764, "header": "tr|A0A8V0ZRF8-1|A0A8V0ZRF8_CHICK Isoform 1 of LIM domain and actin binding 1 OS=Gallus gallus OX=9031 GN=LIMA1 PE=1 SV=1 CANONICAL=A0A8V0ZRF8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZL56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8/entry#A0A8V0ZL56-1", "sequence": { "sequence": "MEPSPFNRRQWTSQSLKITAKELSLVNKNKSSALAERFSRYQKAAEEATAEKKRNSTENLPPHFKRGNLSVLKKKWENPVPGTEPRKETLRSSCAEVRHRVASPELGVGSSLAFSSDTEQIPAAGTASHAQASSGTPGQLQSPGVDSRKSQSHSPESGKMENYLRESREVEKPEASENAESSGKIEKYSVPLNKLKMMFEKGEAAQPKVARDQRKTAIGRRISENSFSSEDLDVGQGEKSHSASDASPALSPDKVETKKSLEMPRLTETSIKDRLAKYQAAVSKQGSSTGLVTTVSVGENSLSFHSSLSEDGNVGQNLESETEVQKPVSTKQQNFGSKSLGQTDASLPKTVKKFQLPAKETCVGCQKTVYPMERLLANQQVFHISCFRCSYCNSKLSLGTYASLRGNIYCKPHFNQLFKAKGNYDEGFGHKQHKELWSSKTECEESLEKTLHGVNATESPQNPGVEDAPIAKVGVLAATMEAKASALPEREEKPAETKKLRIAWPPPSDQSTQGSTLDEGIKVLKPKWPPEEESSKPDVLEDVDLDLKKLRRSSSLKERSRPFTVAASFRTVSVKGHKTDNSSSPSKAERDMLKRSEELEREVVVDKKHKEKIENRNMQNAEEKSVEEERELPGIKTAEHNFVENGQESAETDEEEHAVEEQQTPSEEFLEPNSPKHSSLSNVTAKESSPDQNRKSQDVGFWEGEDMEDLSVEEQIKRNRYYEDDDEE", "length": 728, "header": "tr|A0A8V0ZL56-1|A0A8V0ZRF8_CHICK Computationally mapped isoform of LIM domain and actin binding 1 OS=Gallus gallus OX=9031 GN=LIMA1 PE=1 SV=1 CANONICAL=A0A8V0ZRF8-1" }, "locus": { "chromosome": "34", "start_pos": 429478, "end_pos": 409941, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056323.1", "url": "https://www.ensembl.org/id/ENSGALT00010056323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034095.1", "url": "https://www.ensembl.org/id/ENSGALP00010034095.1" } ] } }, { "isoform_ac": "A0A8V0ZRF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8/entry#A0A8V0ZRF8-1", "sequence": { "sequence": "MEPSPFNRRQWTSQSLKITAKELSLVNKNKSSALAERFSRYQKAAEEATAEKKRNSTENLPPHFKRGNLSVLKKKWENPVPGTEPRKETLRSSCAEVRHRVASPELGVGSSLAFSSDTEQIPAAGTASHAQASSGTPGQLQSPGVDSRKSQSHSPESGKMENYLRESREVEKPEASENAESSGKIEKYSVPLNKLKMMFEKGEAAQPKVARDQRKTAIGRRISENSFSSEDLDVGQGEKSHSASDASPALSPDKVETKKSLEMPRLTETSIKDRLAKYQAAVSKQGSSTGLVTTNEIQASESELKNYKSEQKENMPPSFEDCISYQDGEKVSVGENSLSFHSSLSEDGNVGQNLESETEVQKPVSTKQQNFGSKSLGQTDASLPKTVKKFQLPAKETCVGCQKTVYPMERLLANQQVFHISCFRCSYCNSKLSLGTYASLRGNIYCKPHFNQLFKAKGNYDEGFGHKQHKELWSSKTECEESLEKTLHGVNATESPQNPGVEDAPIAKVGVLAATMEAKASALPEREEKPAETKKLRIAWPPPSDQSTQGSTLDEGIKVLKPKWPPEEESSKPDVLEDVDLDLKKLRRSSSLKERSRPFTVAASFRTVSVKGHKTDNSSSPSKAERDMLKRSEELEREVVVDKKHKEKIENRNMQNAEEKSVEEERELPGIKTAEHNFVENGQESAETDEEEHAVEEQQTPSEEFLEPNSPKHSSLSNVTAKESSPDQNRKSQDVGFWEGEDMEDLSVEEQIKRNRYYEDDDEE", "length": 764, "header": "tr|A0A8V0ZRF8-1|A0A8V0ZRF8_CHICK Isoform 1 of LIM domain and actin binding 1 OS=Gallus gallus OX=9031 GN=LIMA1 PE=1 SV=1 CANONICAL=A0A8V0ZRF8-1" }, "locus": { "chromosome": "34", "start_pos": 429478, "end_pos": 409941, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056319.1", "url": "https://www.ensembl.org/id/ENSGALT00010056319.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034092.1", "url": "https://www.ensembl.org/id/ENSGALP00010034092.1" } ] } }, { "isoform_ac": "A0A8V0ZUG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8/entry#A0A8V0ZUG0-1", "sequence": { "sequence": "MEPSPFNRRQWTSQSLKITAKELSLVNKNKSSALAERFSRYQKAAEEATAEKKRNSTENLPPHFKRGNLSVLKKKWENPVPGTEPRKETLRSSCAEVRHRVASPELGVGSSLAFSSDTEQIPAAGTASHAQASSGTPGQLQSPGVDSRKSQSHSPESGKMENYLRESREVEKPEASENAESSGKIEKYSVPLNKLKMMFEKGEAAQPKVARDQRKTAIGRRISENSFSSEDLDVGQGEKSHSASDASPALSPDKVETKKSLEMPRLTETSIKDRLAKYQAAVSKQGSSTGLVTTNEIQASESELKNYKSEQKENMPPSFEDCISYQDGEKVSVGENSLSFHSSLSEDGNVGQNLESETEVQKPVSTKQQNFGSKSLGQTDASLPKTVKLLFPVLGS", "length": 396, "header": "tr|A0A8V0ZUG0-1|A0A8V0ZRF8_CHICK Computationally mapped isoform of LIM domain and actin binding 1 OS=Gallus gallus OX=9031 GN=LIMA1 PE=1 SV=1 CANONICAL=A0A8V0ZRF8-1" }, "locus": { "chromosome": "34", "start_pos": 426070, "end_pos": 409941, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056315.1", "url": "https://www.ensembl.org/id/ENSGALT00010056315.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034088.1", "url": "https://www.ensembl.org/id/ENSGALP00010034088.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:426878", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426878", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LR10-1", "protein_name": "LIM domain and actin-binding protein 1", "gene_name": "Lima1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESTPFNRRQWTSLSLRVTAKELSLVNKNKSSTIVEIFSKYQKAAEEANMERKKNNTESLPQHFRRGTLSVLKKKWENPVAGAESHTDSLPNSSSDGGHTADHPPAEVTAKAAPGARADREEHTQPRSRFGSRPEAVTQCRYPRSEDSHDFKAQATESQNMENCLGDSRHEAEKPEMSENTETSGKIEKYNVPLNRLKMMFEKGEHSQNKSPWTQGRNAGGRRLSENSCSLDDLEIGAGHLSSSAFNSEKNESKRNLELPRLSETSIKDRMAKYQAAVSKQSSPASYASELKPSESKTHKWEQKENVPPGPEACSIHQEGSKVSATENSLVAHPVPAEDDTCNSQGRSEAQQPIYTKPLSPDARTSSLPESSPSKTAKKFQAPARESCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSKGNYDEGFGHKQHKDLWASKGENEETLGRPAQPPSAGETPHSPGVEDAPIAKVGVLAASMEAKASSQREREENKPAETKKLRIAWPPPAEQGSSGSAPEEGFKVSKPKWPPEDEVCKTEAPEDVDLDLKKLRRSSSLKERSRPFTVAASFRTSSVKSPKPLSPSLRKGWSEPEPEQSEEFGGGTVTQTESPRPSREKESVGKSRWQSEEAEAEAEEAPRGRDGRSFELESESFIGNGASIAEDDVAPAQRSPLEPESPGWPGFGDTTTAKEFNQKSQDVGFWEGEVVRELSVEEQIKRNRYYDEDEDEE", "length": 755 }, "evidence": [ { "id": "A0A8V0ZRF8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HX69-1", "protein_name": "LIM domain and actin-binding protein 1 isoform X1", "gene_name": "Lima1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESSPFNRQQWTSLSLRVTAKELSLVNKNKSSAIMEIFSKYQKAAEEANMEKKRNNTENLPQHFRRGALSVLKKKWENPVAGAESHTDTLPNSSSESAHRVDHPPAEVTKGSASGSRADQEGQTQPKPRFGSRPEAVIQCRHSPSENSLDLKAQATESKKMENCLGDSRHEVEKSEMSEHTDASGKIEKYNVPLNRLKMMFERGEHTQSKILWTQGRNAGGKRISENRRSLDDLEIGLGHLSSSSFNSEKNESKRSLELPRLSETSIKDRMAKYQAAVSKQSSSASYTNELKANGAEIKTHKLEQKENVPPGPEVCISHQEGKKVSTTENSLVAYSSCAEDDACNSQVKSEAQQPVHTKPLSPDARTSSLSESSPSKTVKKFQAPAKEICVGCQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGQIYCKPHFNQLFKSKGNYDEGFGHRPHKDLWANKSENEETSERSPQSPDVGEIPHNSGVEDAPISKVGVLAANMEAKASPQREKEDKPAETKKLRIAWPPPAELGSSGSTMEEGFKGSKPKWPPEDETSKTEALGDVDLDLKKLRRSSSLKERSRPFTVAASFRTSSLKSPKTLSPLRKGWSMSEQNEESGGGIVTAGKQTENAKAPGKKENVRKSRWQREDSAREEVARRSKDIHGVELESENFIENGANIYEGDSGDLVQQSPLDPKSPSWSGFVDTTPTEEFTTQNQKSHDVGFREGEVVRELSVEEQIKRNRYYDEDEDEE", "length": 759 }, "evidence": [ { "id": "A0A8V0ZRF8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9ERG0-1", "protein_name": "LIM domain and actin-binding protein 1", "gene_name": "Lima1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESTPFNRRQWTSLSLRVTAKELSLVNKNKSSAIVEIFSKYQKAAEEANMERKKNNPESLPQHFRRGTLSVLKKKWENPVAGAEFHTDSLPNSSSEGGHTADYPPAEVTDKPAPGVRADREEHTQPKPRFGSRPEAVIQSRYPRSENSHDFKAQATESQKMENCLGDSRHEAEKPETSENTETSGKIEKYNVPLNRLKMMFEKGEHNQTKSLWTQSRNAGGRRLSENNCSLDDWEIGAGHLSSSAFNSEKNESKRNLELPRLSETSIKDRMAKYQAAVSKQSSPASYTNELKTSESKTHKWEQKENVPPGPEACSVHQEGSKVSTTENSLVALSVPAEDDTCNSQVKSEAQQPMHPKPLSPDARTSSLPESSPSKTAKKFQAPAKESCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSKGNYDEGFGHKQHKDLWASKSDNEETLGRPAQPPNAGESPHSPGVEDAPIAKVGVLAASMEAKASSQREREDKPAETKKLRIAWPPPAELGGSGSALEEGIKVSKPKWPPEDDVCKTEAPEDVDLDLKKLRRSSSLKERSRPFTVAASFRTSSIKSPKASSPSLRKGWSESEQSEEFGGGIATMERKQTENARPSGEKENVGKSRWQGEEVPRSKDRSSFELESENFMENGANIAEDDNHVHAQQSPLEPEAPGWSGFVDTTAAKEFTTQNQKSQDVGFWEGEVVRELSVEEQIKRNRYYDEDEDEE", "length": 753 }, "evidence": [ { "id": "A0A8V0ZRF8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHB6-1", "protein_name": "LIM domain and actin-binding protein 1", "gene_name": "LIMA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESSPFNRRQWTSLSLRVTAKELSLVNKNKSSAIVEIFSKYQKAAEETNMEKKRSNTENLSQHFRKGTLTVLKKKWENPGLGAESHTDSLRNSSTEIRHRADHPPAEVTSHAASGAKADQEEQIHPRSRLRSPPEALVQGRYPHIKDGEDLKDHSTESKKMENCLGESRHEVEKSEISENTDASGKIEKYNVPLNRLKMMFEKGEPTQTKILRAQSRSASGRKISENSYSLDDLEIGPGQLSSSTFDSEKNESRRNLELPRLSETSIKDRMAKYQAAVSKQSSSTNYTNELKASGGEIKIHKMEQKENVPPGPEVCITHQEGEKISANENSLAVRSTPAEDDSRDSQVKSEVQQPVHPKPLSPDSRASSLSESSPPKAMKKFQAPARETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSKGNYDEGFGHRPHKDLWASKNENEEILERPAQLANARETPHSPGVEDAPIAKVGVLAASMEAKASSQQEKEDKPAETKKLRIAWPPPTELGSSGSALEEGIKMSKPKWPPEDEISKPEVPEDVDLDLKKLRRSSSLKERSRPFTVAASFQSTSVKSPKTVSPPIRKGWSMSEQSEESVGGRVAERKQVENAKASKKNGNVGKTTWQNKESKGETGKRSKEGHSLEMENENLVENGADSDEDDNSFLKQQSPQEPKSLNWSSFVDNTFAEEFTTQNQKSQDVELWEGEVVKELSVEEQIKRNRYYDEDEDEE", "length": 759 }, "evidence": [ { "id": "A0A8V0ZRF8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "microtubule stabilizing activity", "id": "GO:0140778", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140778", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "negative regulation of actin filament depolymerization", "id": "GO:0030835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030835", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "negative regulation of cilium assembly", "id": "GO:1902018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "positive regulation of actin filament bundle assembly", "id": "GO:0032233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032233", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "actin filament bundle assembly", "id": "GO:0051017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "intestinal cholesterol absorption", "id": "GO:0030299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030299", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "ruffle organization", "id": "GO:0031529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031529", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" }, { "name": "regulation of lamellipodium organization", "id": "GO:1902743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 10, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", 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"id": "A0A8V0ZRM9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ42", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLIRTCFFFACLPVASHVWGRGGQGSSGRLKLTVLSEDRLQMKWKETEGSINGYKVRVKPMAGDSEQEVMLKTKTPKATVGGLSPTKEYTLQVYVLNGSQEALFAKRKFVIEDLKNASQTRNNRRNSGAAPGKNLTSVGSSTVEQSLGMETAPPPLSTVLTHPAKDRAEKKRHKGTQPKGSGETMRSQPSVGVTQTPPPTTKSSQRATANTEREPPGKEKPTRDSLRRGSQFQCDTSAMTDIVLLVDGSWSIGRSNFKLIKEFLSALISPFNIAQDKIRVGLSQYSSDPRTEWDLSAYATRDQVLEAVRNLRYKGGNTFTGLALTHVLEQNLKPDAGARLEAEKLVILLTDGKSQDDANLAAQTLKNMGIEIFAIGVKNADEAELKQVASEPLELTVYNVLDFPLLSSLVGRLTRVLCTRIKERSSKESAGRAVKDIPTNTGPELSPTDLKISAVTSKSMHLAWSPPLSPPKKYRVVYYPSKGGTPKEVLLDGAISSLRLSNLTSHTEYLVSVFPVYDTAVGDGLRGVTSTLPLSAPRSLRVSELSHNSIRLSWKAAQGATQYLVLCSAAPDGAEDYTTEIKVAEPEVLLDGLSPSTEYSIAVYALYGEDASDPASIQETTLALSPPRYLSFSELSHSSVRVSWEPASPAVKGHRVTYMSSRGSNTGEVEVPGTAMSTVLRPLSSLTQYFISVRSMYDEGDSFPITGNVTTLKVPPPRALKVSELSENSLRLHWEAVAASDVVVYQIKWSTAGGEKPQELSIAGNAATAVLPGLQKNTDYKISIWAYYKDGARSDTVSIQHRTTSRSPPTNLFIDSESPTSLQIHWKPPEGRIQHYRITYSPVSDPSTQQTIMASGKSSSVTLQPLLPDRAYKVTVSAVHYTGESESTTATGRTAPVMSKLPSIRGFVPSKTEACPPISSSAGSVRGFDMMEAFGLVEKEYASIKGVAMEPFIFSGSRTFTLFRDIQLTLRTSDVHLFAIPPEHTISILLRLLPDTPKEPFAVWQITDEDFQPLLGVNLDPSKKTLTYFNHDYKADLQEVSFDQQEVKKIFYGSFHKVHLAVSLFKIKLYLDCKKIAERPINTVGSISTAGFIMLGKVTRTRGPRSGSASFQLQSLQVVCNSLGAEEDRCCDLPALRDEESCPTIAPACSCTSGRPGLPGPPGPPGSPGRRGPQGEQGEPGPKGEPGPPGKVGPAGPSGQQGSPGSQGITIQGPVGPPGIKGEKGDTGSPGMQGIPGVQGAPGRDGLQGAKGVRGLEGTAGPPGPPGPRGFQGVTGSRGSSGEKGPPGDVGPTGLPGPKGERGEKGEPQSLATIYQLVSQACERMIQSHVLKFDSFIHEHARKPVPVWEGRLKPGEPGSPGPPGPPGSNGEKGENGLPGQTGKDGYPGERGAPGPKGEKGMAGANEEGIQGPRGRTGPPGEVVLGKPGPKGYPGNTGPQGFPGVRGQPGQPGYSGGCDVSGCYGPGRRGELRSTGQDVFPHSVAVLRSFLPATAGGRAQRSPANTR", "length": 1506, "header": "tr|A0A8V0ZRN3-1|A0A8V0ZRN3_CHICK Isoform 1 of Collagen alpha-1(XX) chain OS=Gallus gallus OX=9031 GN=COL20A1 PE=4 SV=1 CANONICAL=A0A8V0ZRN3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3/entry#A0A8V0ZLA0-1", "sequence": { "sequence": "MLIRTCFFFACLPVASHVWGRGGQGSSGRLKLTVLSEDRLQMKWKETEGSINGYKVRVKPMAGDSEQEVMLKTKTPKATVGGLSPTKEYTLQVYVLNGSQEALFAKRKFVIEDLKNASQTRNNRRNSGAAPGKNLTSVGSSTVEQSLGMETAPPPLSTVLTHPAKDRAEKKRHKGTQPKGSGETMRSQPSVGVTQTPPPTTKSSQRATANTEREPPGKEKPTRDSLRRGSQFQCDTSAMTDIVLLVDGSWSIGRSNFKLIKEFLSALISPFNIAQDKIRVGLSQYSSDPRTEWDLSAYATRDQVLEAVRNLRYKGGNTFTGLALTHVLEQNLKPDAGARLEAEKLVILLTDGKSQDDANLAAQTLKNMGIEIFAIGVKNADEAELKQVASEPLELTVYNVLDFPLLSSLVGRLTRVLCTRIKERSSKESAGRAVKDIPTNTGPELSPTDLKISAVTSKSMHLAWSPPLSPPKKYRVVYYPSKGGTPKEVLLDGAISSLRLSNLTSHTEYLVSVFPVYDTAVGDGLRGVTSTLPLSAPRSLRVSELSHNSIRLSWKAAQGATQYLVLCSAAPDGAEDYTTEIKVAEPEVLLDGLSPSTEYSIAVYALYGEDASDPASIQETTLALSPPRYLSFSELSHSSVRVSWEPASPAVKGHRVTYMSSRGSNTGEVSPQGLDVLSPLPLSSLTQYFISVRSMYDEGDSFPITGNVTTLKVPPPRALKVSELSENSLRLHWEAVAASDVVVYQIKWSTAGGEKPQELSIAGNAATAVLPGLQKNTDYKISIWAYYKDGARSDTVSIQHRTTSRSPPTNLFIDSESPTSLQIHWKPPEGRIQHYRITYSPVSDPSTQQTIMASGKSSSVTLQPLLPDRAYKVTVSAVHYTGESESTTATGRTAPVMSKLPSIRGFVPSKTEGKSPPITSGIGFDMMEAFGLVEKEYASIKGVAMEPFIFSGSRTFTLFRDIQLTLRTSDVHLFAIPPEHTISILLRLLPDTPKEPFAVWQITDEDFQPLLGVNLDPSKKTLTYFNHDYKADLQEVSFDQQEVKKIFYGSFHKVHLAVSLFKIKLYLDCKKIAERPINTVGSISTAGFIMLGKVTRTRGPRSGSASFQLQSLQVVCNSLGAEEDRCCDLPALRDEESCPTIAPACSCTSGRPGLPGPPGPPGSPGRRGPQGEQGEPGPKGEPGPPGKVGPAGPSGQQGSPGSQGITIQGPVGPPGIKGEKGDTGSPGMQGIPGVQGAPGRDGLQGAKGVRGLEGTAGPPGPPGPRGFQGVTGSRGSSGEKGPPGDVGPTGLPGPKGERGEKGEPQSLATIYQLVSQACERMIQSHVLKFDSFIHEHARKPVPVWEGRLKPGEPGSPGPPGPPGSNGEKGENGLPGQTGKDGYPGERGAPGPKGEKGMAGANEEGIQGPRGRTGPPGEVVLGKPGPKGYPGNTGPQGFPGVRGQPGQPGYSGGCDVSGCYGPGRRDFIP", "length": 1468, "header": "tr|A0A8V0ZLA0-1|A0A8V0ZRN3_CHICK Computationally mapped isoform of Collagen alpha-1(XX) chain OS=Gallus gallus OX=9031 GN=COL20A1 PE=4 SV=1 CANONICAL=A0A8V0ZRN3-1" }, "locus": { "chromosome": "20", "start_pos": 9207610, "end_pos": 9167990, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056392.1", "url": "https://www.ensembl.org/id/ENSGALT00010056392.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034145.1", "url": "https://www.ensembl.org/id/ENSGALP00010034145.1" } ] } }, { "isoform_ac": "A0A8V0ZRL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3/entry#A0A8V0ZRL3-1", "sequence": { "sequence": "MLIRTCFFFACLPVASHVWGRGGQGSSGRLKLTVLSEDRLQMKWKETEGSINGYKVRVKPMAGDSEQEVMLKTKTPKATVGGLSPTKEYTLQVYVLNGSQEALFAKRKFVIEDLKNASQTRNNRRNSGAAPGKNLTSVGSSTVEQSLGMETAPPPLSTVLTHPAKDRAEKKRHKGTQPKGSGETMRSQPSVGVTQTPPPTTKSSQRATANTEREPPGKEKPTRDSLRRGSQFQCDTSAMTDIVLLVDGSWSIGRSNFKLIKEFLSALISPFNIAQDKIRVGLSQYSSDPRTEWDLSAYATRDQVLEAVRNLRYKGGNTFTGLALTHVLEQNLKPDAGARLEAEKLVILLTDGKSQDDANLAAQTLKNMGIEIFAIGVKNADEAELKQVASEPLELTVYNVLDFPLLSSLVGRLTRVLCTRIKERSSKESAGRAVKDIPTNTGPELSPTDLKISAVTSKSMHLAWSPPLSPPKKYRVVYYPSKGGTPKEVLLDGAISSLRLSNLTSHTEYLVSVFPVYDTAVGDGLRGVTSTLPLSAPRSLRVSELSHNSIRLSWKAAQGATQYLVLCSAAPDGAEDYTTEIKVAEPEVLLDGLSPSTEYSIAVYALYGEDASDPASIQETTLALSPPRYLSFSELSHSSVRVSWEPASPAVKGHRVTYMSSRGSNTGEVEVPGTAMSTVLRPLSSLTQYFISVRSMYDEGDSFPITGNVTTLKVPPPRALKVSELSENSLRLHWEAVAASDVVVYQIKWSTAGGEKPQELSIAGNAATAVLPGLQKNTDYKISIWAYYKDGARSDTVSIQHRTTSRSPPTNLFIDSESPTSLQIHWKPPEGRIQHYRITYSPVSDPSTQQTIMASGKSSSVTLQPLLPDRAYKVTVSAVHYTGESESTTATGRTAPVMSKLPSIRGFVPSKTEACPPISSSAGSVRGFDMMEAFGLVEKEYASIKGVAMEPFIFSGSRTFTLFRDIQLTLRTSDVHLFAIPPEHTISILLRLLPDTPKEPFAVWQITDEDFQPLLGVNLDPSKKTLTYFNHDYKADLQEVSFDQQEVKKIFYGSFHKVHLAVSLFKIKLYLDCKKIAERPINTVGSISTAGFIMLGKVTRTRGPRSGSASFQLQSLQVVCNSLGAEEDRCCDLPALRDEESCPTIAPACSCTSGRPGLPGPPGPPGSPGRRGPQGEQGEPGPKGEPGPPGKVGPAGPSGQQGSPGSQGITIQGPVGPPGIKGEKGDTGSPGMQGVRGLEGTAGPPGPPGPRGFQGVTGSRGSSGEKGPPGDVGPTGLPGPKGERGEKGEPQSLATIYQLVSQACERMIQSHVLKFDSFIHEHARKPVPVWEGRLKPGEPGSPGPPGPPGSNGEKGENGLPGQTGKDGYPGERGAPGPKGEKGMAGANEEGIQGPRGRTGPPGEVVLGKPGPKGYPGNTGPQGFPGVRGQPGQPGYSGGCDVSGCYGPGRRDFIP", "length": 1454, "header": "tr|A0A8V0ZRL3-1|A0A8V0ZRL3_CHICK Computationally mapped isoform of Collagen alpha-1(XX) chain OS=Gallus gallus OX=9031 GN=COL20A1 PE=4 SV=1 CANONICAL=A0A8V0ZRN3-1" }, "locus": { "chromosome": "20", "start_pos": 9207610, "end_pos": 9167990, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056403.1", "url": "https://www.ensembl.org/id/ENSGALT00010056403.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034152.1", "url": "https://www.ensembl.org/id/ENSGALP00010034152.1" } ] } }, { "isoform_ac": "A0A8V0ZRM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3/entry#A0A8V0ZRM9-1", "sequence": { "sequence": "MLIRTCFFFACLPVASHVWGRGGQGSSGRLKLTVLSEDRLQMKWKETEGSINGYKVRVKPMAGDSEQEVMLKTKTPKATVGGLSPTKEYTLQVYVLNGSQEALFAKRKFVIEDLKNASQTRNNRRNSGAAPGKNLTSVGSSTVEQSLGMETAPPPLSTVLTHPAKDRAEKKRHKGTQPKGSGETMRSQPSVGVTQTPPPTTKSSQRATANTEREPPGKEKPTRDSLRRGSQFQCDTSAMTDIVLLVDGSWSIGRSNFKLIKEFLSALISPFNIAQDKIRVGLSQYSSDPRTEWDLSAYATRDQVLEAVRNLRYKGGNTFTGLALTHVLEQNLKPDAGARLEAEKLVILLTDGKSQDDANLAAQTLKNMGIEIFAIGVKNADEAELKQVASEPLELTVYNVLDFPLLSSLVGRLTRVLCTRIKERSSKESAGRAVKDIPTNTGPELSPTDLKISAVTSKSMHLAWSPPLSPPKKYRVVYYPSKGGTPKEVLLDGAISSLRLSNLTSHTEYLVSVFPVYDTAVGDGLRGVTSTLPLSAPRSLRVSELSHNSIRLSWKAAQGATQYLVLCSAAPDGAEDYTTEIKVAEPEVLLDGLSPSTEYSIAVYALYGEDASDPASIQETTLALSPPRYLSFSELSHSSVRVSWEPASPAVKGHRVTYMSSRGSNTGEVEVPGTAMSTVLRPLSSLTQYFISVRSMYDEGDSFPITGNVTTLKVPPPRALKVSELSENSLRLHWEAVAASDVVVYQIKWSTAGGEKPQELSIAGNAATAVLPGLQKNTDYKISIWAYYKDGARSDTVSIQHRTTSRSPPTNLFIDSESPTSLQIHWKPPEGRIQHYRITYSPVSDPSTQQTIMASGKSSSVTLQPLLPDRAYKVTVSAVHYTGESESTTATGRTAPVMSKLPSIRGFVPSKTEACPPISSSAGSVRGFDMMEAFGLVEKEYASIKGVAMEPFIFSGSRTFTLFRDIQLTLRTSDVHLFAIPPEHTISILLRLLPDTPKEPFAVWQITDEDFQPLLGVNLDPSKKTLTYFNHDYKADLQEVSFDQQEVKKIFYGSFHKVHLAVSLFKIKLYLDCKKIAERPINTVGSISTAGFIMLGKVTRTRGPRSGSASFQLQSLQVVCNSLGAEEDRCCDLPALRDEESCPTIAPACSCTSGRPGLPGPPGPPGSPGRRGPQGEQGEPGPKGEPGPPGKVGPAGPSGQQGSPGSQGITIQGPVGPPGIKGEKGDTGSPGMQGIPGVQGAPGRDGLQGAKGVRGLEGTAGPPGPPGPRGFQGVTGSRGSSGEKGPPGDVGPTGLPGPKGERGEKGEPQSLATIYQLVSQACERMIQSHVLKFDSFIHEHARKPVPVWEGRLKPGEPGSPGPPGPPGSNGEKGENGLPGQTGKDGYPGERGAPGPKGEKGMAGANEEGIQGPRGRTGPPGEVVLGKPGPKGYPGNTGPQGFPGVRGQPGQPGYSGGCDVSGCYGPGRRVLFQFLIIEFCGGIPSSLAISRVE", "length": 1492, "header": "tr|A0A8V0ZRM9-1|A0A8V0ZRM9_CHICK Computationally mapped isoform of Collagen alpha-1(XX) chain OS=Gallus gallus OX=9031 GN=COL20A1 PE=4 SV=1 CANONICAL=A0A8V0ZRN3-1" }, "locus": { "chromosome": "20", "start_pos": 9210705, "end_pos": 9167990, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056429.1", "url": "https://www.ensembl.org/id/ENSGALT00010056429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034173.1", "url": "https://www.ensembl.org/id/ENSGALP00010034173.1" } ] } }, { "isoform_ac": "A0A8V0ZRN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3/entry#A0A8V0ZRN3-1", "sequence": { "sequence": "MLIRTCFFFACLPVASHVWGRGGQGSSGRLKLTVLSEDRLQMKWKETEGSINGYKVRVKPMAGDSEQEVMLKTKTPKATVGGLSPTKEYTLQVYVLNGSQEALFAKRKFVIEDLKNASQTRNNRRNSGAAPGKNLTSVGSSTVEQSLGMETAPPPLSTVLTHPAKDRAEKKRHKGTQPKGSGETMRSQPSVGVTQTPPPTTKSSQRATANTEREPPGKEKPTRDSLRRGSQFQCDTSAMTDIVLLVDGSWSIGRSNFKLIKEFLSALISPFNIAQDKIRVGLSQYSSDPRTEWDLSAYATRDQVLEAVRNLRYKGGNTFTGLALTHVLEQNLKPDAGARLEAEKLVILLTDGKSQDDANLAAQTLKNMGIEIFAIGVKNADEAELKQVASEPLELTVYNVLDFPLLSSLVGRLTRVLCTRIKERSSKESAGRAVKDIPTNTGPELSPTDLKISAVTSKSMHLAWSPPLSPPKKYRVVYYPSKGGTPKEVLLDGAISSLRLSNLTSHTEYLVSVFPVYDTAVGDGLRGVTSTLPLSAPRSLRVSELSHNSIRLSWKAAQGATQYLVLCSAAPDGAEDYTTEIKVAEPEVLLDGLSPSTEYSIAVYALYGEDASDPASIQETTLALSPPRYLSFSELSHSSVRVSWEPASPAVKGHRVTYMSSRGSNTGEVEVPGTAMSTVLRPLSSLTQYFISVRSMYDEGDSFPITGNVTTLKVPPPRALKVSELSENSLRLHWEAVAASDVVVYQIKWSTAGGEKPQELSIAGNAATAVLPGLQKNTDYKISIWAYYKDGARSDTVSIQHRTTSRSPPTNLFIDSESPTSLQIHWKPPEGRIQHYRITYSPVSDPSTQQTIMASGKSSSVTLQPLLPDRAYKVTVSAVHYTGESESTTATGRTAPVMSKLPSIRGFVPSKTEACPPISSSAGSVRGFDMMEAFGLVEKEYASIKGVAMEPFIFSGSRTFTLFRDIQLTLRTSDVHLFAIPPEHTISILLRLLPDTPKEPFAVWQITDEDFQPLLGVNLDPSKKTLTYFNHDYKADLQEVSFDQQEVKKIFYGSFHKVHLAVSLFKIKLYLDCKKIAERPINTVGSISTAGFIMLGKVTRTRGPRSGSASFQLQSLQVVCNSLGAEEDRCCDLPALRDEESCPTIAPACSCTSGRPGLPGPPGPPGSPGRRGPQGEQGEPGPKGEPGPPGKVGPAGPSGQQGSPGSQGITIQGPVGPPGIKGEKGDTGSPGMQGIPGVQGAPGRDGLQGAKGVRGLEGTAGPPGPPGPRGFQGVTGSRGSSGEKGPPGDVGPTGLPGPKGERGEKGEPQSLATIYQLVSQACERMIQSHVLKFDSFIHEHARKPVPVWEGRLKPGEPGSPGPPGPPGSNGEKGENGLPGQTGKDGYPGERGAPGPKGEKGMAGANEEGIQGPRGRTGPPGEVVLGKPGPKGYPGNTGPQGFPGVRGQPGQPGYSGGCDVSGCYGPGRRGELRSTGQDVFPHSVAVLRSFLPATAGGRAQRSPANTR", "length": 1506, "header": "tr|A0A8V0ZRN3-1|A0A8V0ZRN3_CHICK Isoform 1 of Collagen alpha-1(XX) chain OS=Gallus gallus OX=9031 GN=COL20A1 PE=4 SV=1 CANONICAL=A0A8V0ZRN3-1" }, "locus": { "chromosome": "20", "start_pos": 9213807, "end_pos": 9167990, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056435.1", "url": "https://www.ensembl.org/id/ENSGALT00010056435.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034178.1", "url": "https://www.ensembl.org/id/ENSGALP00010034178.1" } ] } }, { "isoform_ac": "A0A8V0ZTJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3/entry#A0A8V0ZTJ0-1", "sequence": { "sequence": "MSYGPARRWSSGRLKLTVLSEDRLQMKWKETEGSINGYKVRVKPMAGDSEQEVMLKTKTPKATVGGLSPTKEYTLQVYVLNGSQEALFAKRKFVIEDLKNASQTRNNRRNSGAAPGKNLTSVGSSTVEQSLGMETAPPPLSTVLTHPAKDRAEKKRHKGTQPKGSGETMRSQPSVGVTQTPPPTTKSSQRATANTEREPPGKEKPTRDSLRRGSQFQCDTSAMTDIVLLVDGSWSIGRSNFKLIKEFLSALISPFNIAQDKIRVGLSQYSSDPRTEWDLSAYATRDQVLEAVRNLRYKGGNTFTGLALTHVLEQNLKPDAGARLEAEKLVILLTDGKSQDDANLAAQTLKNMGIEIFAIGVKNADEAELKQVASEPLELTVYNVLDFPLLSSLVGRLTRVLCTRIKERSSKESAGRAVKDIPTNTGPELSPTDLKISAVTSKSMHLAWSPPLSPPKKYRVVYYPSKGGTPKEVLLDGAISSLRLSNLTSHTEYLVSVFPVYDTAVGDGLRGVTSTLPLSAPRSLRVSELSHNSIRLSWKAAQGATQYLVLCSAAPDGAEDYTTEIKVAEPEVLLDGLSPSTEYSIAVYALYGEDASDPASIQETTLALSPPRYLSFSELSHSSVRVSWEPASPAVKGHRVTYMSSRGSNTGEVEVPGTAMSTVLRPLSSLTQYFISVRSMYDEGDSFPITGNVTTLKVPPPRALKVSELSENSLRLHWEAVAASDVVVYQIKWSTAGGEKPQELSIAGNAATAVLPGLQKNTDYKISIWAYYKDGARSDTVSIQHRTTSRSPPTNLFIDSESPTSLQIHWKPPEGRIQHYRITYSPVSDPSTQQTIMASGKSSSVTLQPLLPDRAYKVTVSAVHYTGESESTTATGRTAPVMSKLPSIRGFVPSKTEACPPISSSAGSVRGFDMMEAFGLVEKEYASIKGVAMEPFIFSGSRTFTLFRDIQLTLRTSDVHLFAIPPEHTISILLRLLPDTPKEPFAVWQITDEDFQPLLGVNLDPSKKTLTYFNHDYKADLQEVSFDQQEVKKIFYGSFHKVHLAVSLFKIKLYLDCKKIAERPINTVGSISTAGFIMLGKVTRTRGPRSGSASFQLQSLQVVCNSLGAEEDRCCDLPALRDEESCPTIAPACSCTSGRPGLPGPPGPPGSPGRRGPQGEQGEPGPKGEPGPPGKVGPAGPSGQQGSPGSQGITIQGPVGPPGIKGEKGDTGSPGMQGIPGVQGAPGRDGLQGAKGVRGLEGTAGPPGPPGPRGFQGVTGSRGSSGEKGPPGDVGPTGLPGPKGERGEKGEPQSLATIYQLVSQACERMIQSHVLKFDSFIHEHARKPVPVWEGRLKPGEPGSPGPPGPPGSNGEKGENGLPGQTGKDGYPGERGAPGPKGEKGMAGANEEGIQGPRGRTGPPGEVVLGKPGPKGYPGNTGPQGFPGVRGQPGQPGYSGGCDVSGCYGPGRRDFIP", "length": 1456, "header": "tr|A0A8V0ZTJ0-1|A0A8V0ZRN3_CHICK Computationally mapped isoform of Collagen alpha-1(XX) chain OS=Gallus gallus OX=9031 GN=COL20A1 PE=4 SV=1 CANONICAL=A0A8V0ZRN3-1" }, "locus": { "chromosome": "20", "start_pos": 9207610, "end_pos": 9170022, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056374.1", "url": "https://www.ensembl.org/id/ENSGALT00010056374.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034134.1", "url": "https://www.ensembl.org/id/ENSGALP00010034134.1" } ] } }, { "isoform_ac": "A0A8V0ZTL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3/entry#A0A8V0ZTL2-1", "sequence": { "sequence": "MLIRTCFFFACLPVASHVWGRGGQGSSGRLKLTVLSEDRLQMKWKETEGSINGYKVRVKPMAGDSEQEVMLKTKTPKATVGGLSPTKEYTLQVYVLNGSQEALFAKRKFVIEDLKNASQTRNNRRNSGAAPGKNLTSVGSSTVEQSLGMETAPPPLSTVLTHPAKDRAEKKRHKGTQPKGSGETMRSQPSVGVTQTPPPTTKSSQRATANTEREPPGKEKPTRDSLRRGSQFQCDTSAMTDIVLLVDGSWSIGRSNFKLIKEFLSALISPFNIAQDKIRVGLSQYSSDPRTEWDLSAYATRDQVLEAVRNLRYKGGNTFTGLALTHVLEQNLKPDAGARLEAEKLVILLTDGKSQDDANLAAQTLKNMGIEIFAIGVKNADEAELKQVASEPLELTVYNVLDFPLLSSLVGRLTRVLCTRIKERSSKESAGRAVKDIPTNTGPELSPTDLKISAVTSKSMHLAWSPPLSPPKKYRVVYYPSKGGTPKEVLLDGAISSLRLSNLTSHTEYLVSVFPVYDTAVGDGLRGVTSTLALSPPRYLSFSELSHSSVRVSWEPASPAVKGHRVTYMSSRGSNTGEVEVPGTAMSTVLRPLSSLTQYFISVRSMYDEGDSFPITGNVTTLKVPPPRALKVSELSENSLRLHWEAVAASDVVVYQIKWSTAGGEKPQELSIAGNAATAVLPGLQKNTDYKISIWAYYKDGARSDTVSIQHRTTSRSPPTNLFIDSESPTSLQIHWKPPEGRIQHYRITYSPVSDPSTQQTIMASGKSSSVTLQPLLPDRAYKVTVSAVHYTGESESTTATGRTAPVMSKLPSIRGFVPSKTEACPPISSSAGSVRGFDMMEAFGLVEKEYASIKGVAMEPFIFSGSRTFTLFRDIQLTLRTSDVHLFAIPPEHTISILLRLLPDTPKEPFAVWQITDEDFQPLLGVNLDPSKKTLTYFNHDYKADLQEVSFDQQEVKKIFYGSFHKVHLAVSLFKIKLYLDCKKIAERPINTVGSISTAGFIMLGKVTRTRGPRSGSASFQLQSLQVVCNSLGAEEDRCCDLPALRDEESCPTIAPACSCTSGRPGLPGPPGPPGSPGRRGPQGEQGEPGPKGEPGPPGKVGPAGPSGQQGSPGSQGITIQGPVGPPGIKGEKGDTGSPGMQGIPGVQGAPGRDGLQGAKGVRGLEGTAGPPGPPGPRGFQGVTGSRGSSGEKGPPGDVGPTGLPGPKGERGEKGEPQSLATIYQLVSQACERMIQSHVLKFDSFIHEHARKPVPVWEGRLKPGEPGSPGPPGPPGSNGEKGENGLPGQTGKDGYPGERGAPGPKGEKGMAGANEEGIQGPRGRTGPPGEVVLGKPGPKGYPGNTGPQGFPGVRGQPGQPGYSGGCDVSGCYGPGRRDFIP", "length": 1382, "header": "tr|A0A8V0ZTL2-1|A0A8V0ZRN3_CHICK Computationally mapped isoform of Collagen alpha-1(XX) chain OS=Gallus gallus OX=9031 GN=COL20A1 PE=4 SV=1 CANONICAL=A0A8V0ZRN3-1" }, "locus": { "chromosome": "20", "start_pos": 9207610, "end_pos": 9167990, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056412.1", "url": "https://www.ensembl.org/id/ENSGALT00010056412.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034159.1", "url": "https://www.ensembl.org/id/ENSGALP00010034159.1" } ] } }, { "isoform_ac": "A0A8V0ZZ19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3/entry#A0A8V0ZZ19-1", "sequence": { "sequence": "MLIRTCFFFACLPVASHVWGRGGQGSSGRLKLTVLSEDRLQMKWKETEGSINGYKVRVKPMAGDSEQEVMLKTKTPKATVGGLSPTKEYTLQVYVLNGSQEALFAKRKFVIEDLKNASQTRNNRRNSGAAPGKNLTSVGSSTVEQSLGMETAPPPLSTVLTHPAKDRAEKKRHKGTQPKGSGETMRSQPSVGVTQTPPPTTKSSQRATANTEREPPGKEKPTRDSLRRGSQFQCDTSAMTDIVLLVDGSWSIGRSNFKLIKEFLSALISPFNIAQDKIRVGLSQYSSDPRTEWDLSAYATRDQVLEAVRNLRYKGGNTFTGLALTHVLEQNLKPDAGARLEAEKLVILLTDGKSQDDANLAAQTLKNMGIEIFAIGVKNADEAELKQVASEPLELTVYNVLDFPLLSSLVGRLTRVLCTRIKERSSKESAGRAVKDIPTNTGPELSPTDLKISAVTSKSMHLAWSPPLSPPKKYRVVYYPSKGGTPKEVLLDGAISSLRLSNLTSHTEYLVSVFPVYDTAVGDGLRGVTSTLPLSAPRSLRVSELSHNSIRLSWKAAQGATQYLVLCSAAPDGAEDYTTEIKVAEPEVLLDGLSPSTEYSIAVYALYGEDASDPASIQETTLALSPPRYLSFSELSHSSVRVSWEPASPAVKGHRVTYMSSRGSNTGEVEVPGTAMSTVLRPLSSLTQYFISVRSMYDEGDSFPITGNVTTLKVPPPRALKVSELSENSLRLHWEAVAASDVVVYQIKWSTAGGEKPQELSIAGNAATAVLPGLQKNTDYKISIWAYYKDGARSDTVSIQHRTTSRSPPTNLFIDSESPTSLQIHWKPPEGRIQHYRITYSPVSDPSTQQTIMASGKSSSVTLQPLLPDRAYKVTVSAVHYTGESESTTATGRTAPVMSKLPSIRGFVPSKTEACPPISSSAGSVRGFDMMEAFGLVEKEYASIKGVAMEPFIFSGSRTFTLFRDIQLTLRTSDVHLFAIPPEHTISILLRLLPDTPKEPFAVWQITDEDFQPLLGVNLDPSKKTLTYFNHDYKADLQEVSFDQQEVKKIFYGSFHKVHLAVSLFKIKLYLDCKKIAERPINTVGSISTAGFIMLGKVTRTRGPRSGSASFQLQSLQVVCNSLGAEEDRCCDLPALRDEESCPTIAPACSCTSGRPGLPGPPGPPGSPGRRGPQGEQGEPGPKGEPGPPGKVGPAGPSGQQGSPGSQGITIQGPVGPPGIKGEKGDTGSPGMQGIPGVQGAPGRDGLQGAKGVRGLEGTAGPPGPPGPRGFQGVTGSRGSSGEKGPPGDVGPTGLPGPKGERGEKVSFPGAVRQALERVDVGEPQSLATIYQLVSQACERMIQSHVLKFDSFIHEHARKPVPVWEGRLKPGEPGSPGPPGPPGSNGEKGENGLPGQTGKDGYPGERGAPGPKGEKGMAGANEEGIQGPRGRTGPPGEVVLGKPGPKGYPGNTGPQGFPGVRGQPGQPGYSGGCDVSGCYGPGRRDFIP", "length": 1488, "header": "tr|A0A8V0ZZ19-1|A0A8V0ZRN3_CHICK Computationally mapped isoform of Collagen alpha-1(XX) chain OS=Gallus gallus OX=9031 GN=COL20A1 PE=4 SV=1 CANONICAL=A0A8V0ZRN3-1" }, "locus": { "chromosome": "20", "start_pos": 9207610, "end_pos": 9167990, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056383.1", "url": "https://www.ensembl.org/id/ENSGALT00010056383.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034141.1", "url": "https://www.ensembl.org/id/ENSGALP00010034141.1" } ] } }, { "isoform_ac": "A0A8V0ZZ42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3/entry#A0A8V0ZZ42-1", "sequence": { "sequence": "MLIRTCFFFACLPVASHVWGRGGQGSSGRLKLTVLSEDRLQMKWKETEGSINGYKVRVKPMAGDSEQEVMLKTKTPKATVGGLSPTKEYTLQVYVLNGSQEALFAKRKFVIEDLKNASQTRNNRRNSGAAPGKNLTSVGSSTVEQSLGMETAPPPLSTVLTHPAKDRAEKKRHKGTQPKGSGETMRSQPSVGVTQTPPPTTKSSQRATANTEREPPGKEKPTRDSLRRGSQFQCDTSAMTDIVLLVDGSWSIGRSNFKLIKEFLSALISPFNIAQDKIRVGLSQYSSDPRTEWDLSAYATRDQVLEAVRNLRYKGGNTFTGLALTHVLEQNLKPDAGARLEAEKLVILLTDGKSQDDANLAAQTLKNMGIEIFAIGVKNADEAELKQVASEPLELTVYNVLDFPLLSSLVGRLTRVLCTRIKERSSKESAGRAVKDIPTNTGPELSPTDLKISAVTSKSMHLAWSPPLSPPKKYRVVYYPSKGGTPKEVLLDGAISSLRLSNLTSHTEYLVSVFPVYDTAVGDGLRGVTSTLPLSAPRSLRVSELSHNSIRLSWKAAQGATQYLVLCSAAPDGAEDYTTEIKVAEPEVLLDGLSPSTEYSIAVYALYGEDASDPASIQETTLALSPPRYLSFSELSHSSVRVSWEPASPAVKGHRVTYMSSRGSNTGEVEVPGTAMSTVLRPLSSLTQYFISVRSMYDEGDSFPITGNVTTSSRSPPTNLFIDSESPTSLQIHWKPPEGRIQHYRITYSPVSDPSTQQTIMASGKSSSVTLQPLLPDRAYKVTVSAVHYTGESESTTATGRTAPVMSKLPSIRGFVPSKTEACPPISSSAGSVRGFDMMEAFGLVEKEYASIKGVAMEPFIFSGSRTFTLFRDIQLTLRTSDVHLFAIPPEHTISILLRLLPDTPKEPFAVWQITDEDFQPLLGVNLDPSKKTLTYFNHDYKADLQEVSFDQQEVKKIFYGSFHKVHLAVSLFKIKLYLDCKKIAERPINTVGSISTAGFIMLGKVTRTRGPRSGSASFQLQSLQVVCNSLGAEEDRCCDLPALRDEESCPTIAPACSCTSGRPGLPGPPGPPGSPGRRGPQGEQGEPGPKGEPGPPGKVGPAGPSGQQGSPGSQGITIQGPVGPPGIKGEKGDTGSPGMQGIPGVQGAPGRDGLQGAKGVRGLEGTAGPPGPPGPRGFQGVTGSRGSSGEKGPPGDVGPTGLPGPKGERGEKGEPQSLATIYQLVSQACERMIQSHVLKFDSFIHEHARKPVPVWEGRLKPGEPGSPGPPGPPGSNGEKGENGLPGQTGKDGYPGERGAPGPKGEKGMAGANEEGIQGPRGRTGPPGEVVLGKPGPKGYPGNTGPQGFPGVRGQPGQPGYSGGCDVSGCYGPGRRDFIP", "length": 1380, "header": "tr|A0A8V0ZZ42-1|A0A8V0ZRN3_CHICK Computationally mapped isoform of Collagen alpha-1(XX) chain OS=Gallus gallus OX=9031 GN=COL20A1 PE=4 SV=1 CANONICAL=A0A8V0ZRN3-1" }, "locus": { "chromosome": "20", "start_pos": 9207610, "end_pos": 9167990, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056421.1", "url": "https://www.ensembl.org/id/ENSGALT00010056421.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034167.1", "url": "https://www.ensembl.org/id/ENSGALP00010034167.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-8948216", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8948216", "resource": "Reactome", "description": "Collagen chain trimerization" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 117, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZRN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN3" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 241, "end_pos": 413, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 134, "end_pos": 136 }, { "start_pos": 502, "end_pos": 504 }, { "start_pos": 708, "end_pos": 710 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNR3-1", "uniprot_ac": "A0A8V0ZNR3", "uniprot_id": "A0A8V0ZNR3_CHICK", "mass": { "chemical_mass": 14504.0, "monoisotopic_mass": 14504.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Keratin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZNR3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31203:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31203:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZLL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLHQETQEVVLVQQASSTSKICCQSFQLSPELCLPQREMSCCRPCVPSRCGASGPTPLASSCSEPCVARCADSTVAIQASPVVVTLPGPILTSFPQSTAVGSSLSAAVGSSLSTAGVPISSGGSLGLGGSGLCLPRQPCSFNC", "length": 144, "header": "tr|A0A8V0ZNR3-1|A0A8V0ZNR3_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZNR3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR3/entry#A0A8V0ZLL6-1", "sequence": { "sequence": "MSCCRPCVPSRCGASGPTPLASSCSEPCVARCADSTVAIQASPVVVTLPGPILTSFPQSTAVGSSLSAAVGSSLSTAGVPISSGGSLGLGGSGLCLPRQPCSFNC", "length": 105, "header": "tr|A0A8V0ZLL6-1|A0A8V0ZNR3_CHICK Computationally mapped isoform of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZNR3-1" }, "locus": { "chromosome": "10", "start_pos": 761369, "end_pos": 761055, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053676.1", "url": "https://www.ensembl.org/id/ENSGALT00010053676.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032330.1", "url": "https://www.ensembl.org/id/ENSGALP00010032330.1" } ] } }, { "isoform_ac": "A0A8V0ZNR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR3/entry#A0A8V0ZNR3-1", "sequence": { "sequence": "MLLHQETQEVVLVQQASSTSKICCQSFQLSPELCLPQREMSCCRPCVPSRCGASGPTPLASSCSEPCVARCADSTVAIQASPVVVTLPGPILTSFPQSTAVGSSLSAAVGSSLSTAGVPISSGGSLGLGGSGLCLPRQPCSFNC", "length": 144, "header": "tr|A0A8V0ZNR3-1|A0A8V0ZNR3_CHICK Isoform 1 of Keratin OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZNR3-1" }, "locus": { "chromosome": "10", "start_pos": 761369, "end_pos": 760776, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053673.1", "url": "https://www.ensembl.org/id/ENSGALT00010053673.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032329.1", "url": "https://www.ensembl.org/id/ENSGALP00010032329.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 57, "start_aa": "Thr", "end_pos": 57, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr57", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 57 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNF4-1", "uniprot_ac": "A0A8V0ZNF4", "uniprot_id": "A0A8V0ZNF4_CHICK", "mass": { "chemical_mass": 112878.0, "monoisotopic_mass": 112878.0 }, "refseq": { "ac": "XP_024999854", "name": "protein AF-17 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999854" }, "gene_names": [ { "name": "MLLT6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4" } ] }, { "name": "MLLT6", "type": "synonym", "evidence": [ { "id": "XP_024999854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999854" } ] } ], "protein_names": [ { "name": "MLLT6, PHD finger containing", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4/entry#names_and_taxonomy" } ] }, { "name": "protein AF-17 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_024999854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999854" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_024999854.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024999854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999854" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MLLT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4", "locus": { "chromosome": "27", "start_pos": 3991140, "end_pos": 3953210, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022085", "url": "https://www.ensembl.org/id/ENSGALG00010022085" } ] } } ], "crossref": [ { "id": "A0A8V0ZNF4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNF4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15574", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15574", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15709", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15709", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419995", "url": "https://www.ncbi.nlm.nih.gov/gene/419995", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZLN1", "url": "https://www.orthodb.org/?gene=A0A8V0ZLN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNF4", "url": "https://www.orthodb.org/?gene=A0A8V0ZNF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13793:SF90", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13793:SF90", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13831", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13831", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024999854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024999854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEMVGGCCVCSDERGWAENPLVYCDGHGCNVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMACNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFNKMKTSRHSAGSSFIAGRRSRSTSPTQEKHVSHHDRPKKSRKDKERPKQKHKKRPESPTSLPTPTVPIAAEKGSTSHHEGSKETSEVGRSEVKGKKSSSHGSSHKGKKTGSGKSSAGFSSASSSSAFQPAGTSCSSLQCSQDFVAFPKLEQDDEKYRKPVSSSSSSHCSPLYEGQKGDIFEQKVIFSGFGSIMRFSTSAVSQPRGRDASPVDYKASNPISGPSVTGSVASSSSHKRMPSLSMEEGEVLKEKKHKGSKKNKHGPGRPKGGKSKEMLGAQLAGSTSTSSSPFSGGSLVSSSISNSSRPFSHTGNLPSLSMESPLLSSGIYTSNKDPISHGGGVLRAVCSTPLSSSLLAHQGTASIPPLNRSPFASTIPTSSSSSVSTTQVFSLAGSTFSLPSSHIFGSPLTSGLSINPLLNQSESSRAEPDLEDCSFGCRGTSPQESLSSMSPISSLPTLFDQTVSCSSSGQLENVPQATPNIEQLLEKQGNGEAGVNIVEMLKALHSLQKENQRLQEQIMTLTAKKERLQLLNVQLSVPFPVVTSSNGPGSQAHYILPTNVCNNDSLSISKSPPCKNSFGIENSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPMLQQSPASLPLPGVQQVNGLARVAGSGLGGGTTASHSLSTVPMVDGLMGTVAGGQQMPINGILGNLNGAQAAQPPSALTQASGPPTLQLSTSLSSMPSLSPLTEQQRHVLHQHEQQLQQLQQLLTSQPLNPEQQALVFQMMQQIQQKRELQRLQMTSSSQLSMSSLLAATSTPLLHSSTSAPMTSAPQPPPNSSSLMASLSPQQLNPSNALLAPPQATPPLSAPGSSLMASGTGIPPVLTAQTNPFLNLQADGNTPKGTSMNEKGAPLTQDKG", "length": 1067, "header": "tr|A0A8V0ZNF4-1|A0A8V0ZNF4_CHICK Isoform 1 of MLLT6, PHD finger containing OS=Gallus gallus OX=9031 GN=MLLT6 PE=4 SV=1 CANONICAL=A0A8V0ZNF4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4/entry#A0A8V0ZLN1-1", "sequence": { "sequence": "MKEMVGGCCVCSDERGWAENPLVYCDGHGCNVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMACNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFNKMKTSRHSAGSSFIAGRRSRSTSPTQEKHVSHHDRPKKSRKDKERPKQKHKKRPESPTSLPTPTVPIAAEKGSTSHHEGSKETSEVGRSEVKGKKSSSHGSSHKGKKTGSGKSSAGFSSASSSSAFQPAGTSCSSLQCSQDFVAFPKLEQDDEKYRKPVSSSSSSHCSPLYEGQKGDIFEQKVIFSGFGSIMRFSTSAVSQPRGRDASPVDYKASNPISGPSVTGSVASSSSHKRMPSLSMEEGEVLKEKKHKGSKKNKHGPGRPKGGKSKEMLGAQLAGSTSTSSSPFSGGSLVSSSISNSSRPFSHTGNLPSLSMESPLLSSGIYTSNKDPISHGGGVLRAVCSTPLSSSLLAHQGTASIPPLNRSPFASTIPTSSSSSVSTTQVFSLAGSTFSLPSSHIFGSPLTSGLSINPLLNQSESSRAEPDLEDCSFGCRGTSPQESLSSMSPISSLPTLFDQTVSCSSSGQLENVPQATPNIEQLLEKQGNGEAGVNIVEMLKALHSLQKENQRLQEQIMTLTAKKERLQLLNVQLSVPFPVVTSSNGPGSQAHYILPTNVCNNDSLSISKSPPCKNSFGIENSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPMLQQSPASLPLPGVQQVNGLARVAGSGLGGGTTASHSLSTVPMVDGLMGTVAGGQQMPINGILGNLNGAQAAQPPSALTQASGPPTLQLSTSLSSMPSLSPLTEQQRHVLHQHEQQLQQLQQLLTSQPLNPEQQALVFQMMQQIQQKRELQRLQMTSSSQLSMSSLLAATSTPLLHSSTSAPMTSAPQPPPNSSSLMASLSPQQLNPSNALLAPPQATPPLSAPGSSLMASGTGIPPVLTAQTNPFLNLQADGNTPKGTVRMLLALP", "length": 1061, "header": "tr|A0A8V0ZLN1-1|A0A8V0ZNF4_CHICK Computationally mapped isoform of MLLT6, PHD finger containing OS=Gallus gallus OX=9031 GN=MLLT6 PE=4 SV=1 CANONICAL=A0A8V0ZNF4-1" }, "locus": { "chromosome": "27", "start_pos": 3987845, "end_pos": 3953386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053725.1", "url": "https://www.ensembl.org/id/ENSGALT00010053725.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032354.1", "url": "https://www.ensembl.org/id/ENSGALP00010032354.1" } ] } }, { "isoform_ac": "A0A8V0ZNF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4/entry#A0A8V0ZNF4-1", "sequence": { "sequence": "MKEMVGGCCVCSDERGWAENPLVYCDGHGCNVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMACNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFNKMKTSRHSAGSSFIAGRRSRSTSPTQEKHVSHHDRPKKSRKDKERPKQKHKKRPESPTSLPTPTVPIAAEKGSTSHHEGSKETSEVGRSEVKGKKSSSHGSSHKGKKTGSGKSSAGFSSASSSSAFQPAGTSCSSLQCSQDFVAFPKLEQDDEKYRKPVSSSSSSHCSPLYEGQKGDIFEQKVIFSGFGSIMRFSTSAVSQPRGRDASPVDYKASNPISGPSVTGSVASSSSHKRMPSLSMEEGEVLKEKKHKGSKKNKHGPGRPKGGKSKEMLGAQLAGSTSTSSSPFSGGSLVSSSISNSSRPFSHTGNLPSLSMESPLLSSGIYTSNKDPISHGGGVLRAVCSTPLSSSLLAHQGTASIPPLNRSPFASTIPTSSSSSVSTTQVFSLAGSTFSLPSSHIFGSPLTSGLSINPLLNQSESSRAEPDLEDCSFGCRGTSPQESLSSMSPISSLPTLFDQTVSCSSSGQLENVPQATPNIEQLLEKQGNGEAGVNIVEMLKALHSLQKENQRLQEQIMTLTAKKERLQLLNVQLSVPFPVVTSSNGPGSQAHYILPTNVCNNDSLSISKSPPCKNSFGIENSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPMLQQSPASLPLPGVQQVNGLARVAGSGLGGGTTASHSLSTVPMVDGLMGTVAGGQQMPINGILGNLNGAQAAQPPSALTQASGPPTLQLSTSLSSMPSLSPLTEQQRHVLHQHEQQLQQLQQLLTSQPLNPEQQALVFQMMQQIQQKRELQRLQMTSSSQLSMSSLLAATSTPLLHSSTSAPMTSAPQPPPNSSSLMASLSPQQLNPSNALLAPPQATPPLSAPGSSLMASGTGIPPVLTAQTNPFLNLQADGNTPKGTSMNEKGAPLTQDKG", "length": 1067, "header": "tr|A0A8V0ZNF4-1|A0A8V0ZNF4_CHICK Isoform 1 of MLLT6, PHD finger containing OS=Gallus gallus OX=9031 GN=MLLT6 PE=4 SV=1 CANONICAL=A0A8V0ZNF4-1" }, "locus": { "chromosome": "27", "start_pos": 3988557, "end_pos": 3953386, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053713.1", "url": "https://www.ensembl.org/id/ENSGALT00010053713.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032351.1", "url": "https://www.ensembl.org/id/ENSGALP00010032351.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1012, "start_aa": "Thr", "end_pos": 1012, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1012", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 246, "start_aa": "Thr", "end_pos": 246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr246", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4" } ], "pmid": "" }, { "name": "histone reader activity", "id": "GO:0140566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140566", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZNX4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4#function" }, { "database": "UniProtKB", "id": "ARBA00059259", "url": "https://www.uniprot.org/uniprotkb/ARBA00059259#function" }, { "database": "UniProtKB", "id": "A0A8V0ZLR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INPP5J", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4", "locus": { "chromosome": 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PF22669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1660499", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855183", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855183", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1855204", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855204", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "11392", "url": "https://www.rhea-db.org/rhea/11392", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19797", "url": "https://www.rhea-db.org/rhea/19797", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "22764", "url": "https://www.rhea-db.org/rhea/22764", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZLR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZLR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPSPAAGGPTSGYRAGPRSPRRRTRAGPSPSRSRCPRCRPSGRASPRAAPRCWARSSAPRSATCPASRCPKPSPATASRPGRPPALWGCPRPCPASSSPPGASGWARRWPSPSRSPRSCPCSGGAGRPSALRAPADPPMLSWAARGRPWRTERSGELTAAVGGQRDPLCVGHRLRGGWGGPWGLTRVVPYSPLFLLSITVVTWNVGTAMPPNDVTSLLHLNTGETNDADMIAIGLQEVNSKINKRLKDALFTDQWSELFMDVLSPFHFVLVSTVRMQGVILLVFAKYYHLPFLQDIQTDCTRTGLGGYWGNKGGVSVRLSIFGHMVCFLNCHLPAHLEKAEQRKEDFATILHMQQFEGRAASGILDHDLVFWFGDLNFRIESLDIRFVKYAIDNNILSQLWEKDQLNIAKSTWPVLSGFQEGPLNFPPTFKFDVGTNKYDSSAKKRKPAWTDRILWKIKSPSSGAGGRRPSRGVLSVSQLCYCSHMEYTVSDHKPVAAIFAVQFASKADKPLVEIYVADEWIRPEQAVVKYKMAAGFHRSSWDWIGLYRVGFRHPKDYVSYVWPCAQPGARLLQVMFSEEALPKGKGEYILGYYSNTSSSIVGVTEPFQISLPRSEEGSSATDSSGSSSEEEDDSTLVLLAPKSRSPSPGKMKRHRSRSPSLAKFQGLILRPSSRDRGSSRSPSPQSRRGLTGDIPAIHLPQLELGRRGSKAKESGQVANSQEGSPGSFYQTVREQPCIARRAAVDNPLARADPRNLGLLPALRLETIDQAMGRRRESADQGYPCRRMSPTSPPCSTSPKEGGSPRELDGYSCTMGR", "length": 818, "header": "tr|A0A8V0ZNX4-1|A0A8V0ZNX4_CHICK Isoform 1 of Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A OS=Gallus gallus OX=9031 GN=INPP5J PE=3 SV=1 CANONICAL=A0A8V0ZNX4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZLR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4/entry#A0A8V0ZLR2-1", "sequence": { "sequence": "TEGSASGRLLGGPGRRTGSPPEPDITVVTWNVGTAMPPNDVTSLLHLNTGETNDADMIAIGLQEVNSKINKRLKDALFTDQWSELFMDVLSPFHFVLVSTVRMQGVILLVFAKYYHLPFLQDIQTDCTRTGLGGYWGNKGGVSVRLSIFGHMVCFLNCHLPAHLEKAEQRKEDFATILHMQQFEGRAASGILDHDLVFWFGDLNFRIESLDIRFVKYAIDNNILSQLWEKDQLNIAKSTWPVLSGFQEGPLNFPPTFKFDVGTNKYDSSAKKRKPAWTDRILWKIKSPSSGAGGRRPSRGVLSVSQLCYCSHMEYTVSDHKPVAAIFAVQFASKADKPLVEIYVADEWIRPEQAVVKYKMAAGFHRSSWDWIGLYRVGFRHPKDYVSYVWPCAQPGARLLQVMFSEEALPKGKGEYILGYYSNTSSSIVGVTEPFQISLPRSEEGSSATDSSGSSSEEEDDSTLVLLAPKSRSPSPGKMKRHRSRSPSLAKFQGLILRPSSRDRGSSRSPSPQSRRAPPPGLSGARGAAGLPSPAPGPPAGIARTERHRRSPARPTPDVQHRGAAEWSSDAVRVSARPGLR", "length": 581, "header": "tr|A0A8V0ZLR2-1|A0A8V0ZNX4_CHICK Computationally mapped isoform of Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A OS=Gallus gallus OX=9031 GN=INPP5J PE=3 SV=1 CANONICAL=A0A8V0ZNX4-1" }, "locus": { "chromosome": "15", "start_pos": 10006485, "end_pos": 9999748, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053792.1", "url": "https://www.ensembl.org/id/ENSGALT00010053792.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032384.1", "url": "https://www.ensembl.org/id/ENSGALP00010032384.1" } ] } }, { "isoform_ac": "A0A8V0ZNI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4/entry#A0A8V0ZNI5-1", "sequence": { "sequence": "RPVLKYWLQEVNSKINKRLKDALFTDQWSELFMDVLSPFHFVLVSTVRMQGVILLVFAKYYHLPFLQDIQTDCTRTGLGGYWGNKGGVSVRLSIFGHMVCFLNCHLPAHLEKAEQRKEDFATILHMQQFEGRAASGILDHDLVFWFGDLNFRIESLDIRFVKYAIDNNILSQLWEKDQLNIAKSTWPVLSGFQEGPLNFPPTFKFDVGTNKYDSSAKKRKPAWTDRILWKIKSPSSGAGGRRPSRGVLSVSQLCYCSHMEYTVSDHKPVAAIFAVQFASKADKPLVEIYVADEWIRPEQAVVKYKMAAGFHRSSWDWIGLYRVGFRHPKDYVSYVWPCAQPGARLLQVMFSEEALPKGKGEYILGYYSNTSSSIVGVTEPFQISLPRSEEGSSATDSSGSSSEEEDDSTLVLLAPKSRSPSPGKMKRHRSRSPSLAKFQGLILRPSSRDRGSSRSPSPQSRRGLTGDIPAIHLPQLELGRRGSKAKESGQVANSQEGSPGSFYQTVREQPCIARRAAVDNPLARADPRNLGLLPALRLETIDQAMGRRRESADQGYPCRRMSPTSPPCSTSPKEGGSPRELDGYSCTMGR", "length": 590, "header": "tr|A0A8V0ZNI5-1|A0A8V0ZNI5_CHICK Computationally mapped isoform of Inositol polyphosphate-5-phosphatase J OS=Gallus gallus OX=9031 GN=INPP5J PE=3 SV=1 CANONICAL=A0A8V0ZNX4-1" }, "locus": { "chromosome": "15", "start_pos": 10005395, "end_pos": 10001042, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053784.1", "url": "https://www.ensembl.org/id/ENSGALT00010053784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032381.1", "url": "https://www.ensembl.org/id/ENSGALP00010032381.1" } ] } }, { "isoform_ac": "A0A8V0ZNX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4/entry#A0A8V0ZNX4-1", "sequence": { "sequence": "MEPSPAAGGPTSGYRAGPRSPRRRTRAGPSPSRSRCPRCRPSGRASPRAAPRCWARSSAPRSATCPASRCPKPSPATASRPGRPPALWGCPRPCPASSSPPGASGWARRWPSPSRSPRSCPCSGGAGRPSALRAPADPPMLSWAARGRPWRTERSGELTAAVGGQRDPLCVGHRLRGGWGGPWGLTRVVPYSPLFLLSITVVTWNVGTAMPPNDVTSLLHLNTGETNDADMIAIGLQEVNSKINKRLKDALFTDQWSELFMDVLSPFHFVLVSTVRMQGVILLVFAKYYHLPFLQDIQTDCTRTGLGGYWGNKGGVSVRLSIFGHMVCFLNCHLPAHLEKAEQRKEDFATILHMQQFEGRAASGILDHDLVFWFGDLNFRIESLDIRFVKYAIDNNILSQLWEKDQLNIAKSTWPVLSGFQEGPLNFPPTFKFDVGTNKYDSSAKKRKPAWTDRILWKIKSPSSGAGGRRPSRGVLSVSQLCYCSHMEYTVSDHKPVAAIFAVQFASKADKPLVEIYVADEWIRPEQAVVKYKMAAGFHRSSWDWIGLYRVGFRHPKDYVSYVWPCAQPGARLLQVMFSEEALPKGKGEYILGYYSNTSSSIVGVTEPFQISLPRSEEGSSATDSSGSSSEEEDDSTLVLLAPKSRSPSPGKMKRHRSRSPSLAKFQGLILRPSSRDRGSSRSPSPQSRRGLTGDIPAIHLPQLELGRRGSKAKESGQVANSQEGSPGSFYQTVREQPCIARRAAVDNPLARADPRNLGLLPALRLETIDQAMGRRRESADQGYPCRRMSPTSPPCSTSPKEGGSPRELDGYSCTMGR", "length": 818, "header": "tr|A0A8V0ZNX4-1|A0A8V0ZNX4_CHICK Isoform 1 of Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A OS=Gallus gallus OX=9031 GN=INPP5J PE=3 SV=1 CANONICAL=A0A8V0ZNX4-1" }, "locus": { "chromosome": "15", "start_pos": 10005395, "end_pos": 9998724, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053802.1", "url": "https://www.ensembl.org/id/ENSGALT00010053802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032390.1", "url": "https://www.ensembl.org/id/ENSGALP00010032390.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11, "start_aa": "Thr", "end_pos": 11, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-1660499", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1660499", "resource": "Reactome", "description": "Synthesis of PIPs at the plasma membrane" }, { "id": "R-GGA-1855183", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855183", "resource": "Reactome", "description": "Synthesis of IP2, IP, and Ins in the cytosol" }, { "id": "R-GGA-1855204", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855204", "resource": "Reactome", "description": "Synthesis of IP3 and IP4 in the cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "plasma membrane bounded cell projection", "id": "GO:0120025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120025", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "growth cone", "id": "GO:0030426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "dendritic shaft", "id": "GO:0043198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity", "id": "GO:0004439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004439", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "inositol-polyphosphate 5-phosphatase activity", "id": "GO:0004445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004445", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity", "id": "GO:0034485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "inositol trisphosphate phosphatase activity", "id": "GO:0046030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phosphatidylinositol dephosphorylation", "id": "GO:0046856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" }, { "name": "negative regulation of microtubule polymerization", "id": "GO:0031115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031115", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11392", "name": "", "equation": "1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YRC1-1", "A0A8V0ZNX4-1" ], "evidence": [ { "id": "11392", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11392" } ] }, { "id": "19797", "name": "", "equation": "1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YRC1-1", "A0A8V0ZNX4-1" ], "evidence": [ { "id": "19797", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19797" } ] }, { "id": "22764", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XJN9-1", "A0A8V0Y798-1", "A0A8V0YRC1-1", "A0A8V0ZNX4-1", "A0A8V1AF93-1" ], "evidence": [ { "id": "22764", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22764" } ] }, { "id": "R-GGA-1675949", "name": "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZTL7-1", "A0A8V0Z2V5-1", "A0A8V0ZNX4-1" ], "evidence": [ { "id": "R-GGA-1675949", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1675949" } ] }, { "id": "R-GGA-1676177", "name": "PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XJN9-1", "A0A8V0Y798-1", "A0A8V0ZNX4-1" ], "evidence": [ { "id": "R-GGA-1676177", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1676177" } ] }, { "id": "R-GGA-1855174", "name": "I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YRC1-1", "A0A8V0Y798-1", "A0A8V0ZNX4-1" ], "evidence": [ { "id": "R-GGA-1855174", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855174" } ] }, { "id": "R-GGA-1855218", "name": "I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5F480-1", "A0A8V0ZTL7-1", "A0A8V0YRC1-1", "A0A8V0Z2V5-1", "A0A8V0Y798-1", "A0A8V0ZNX4-1" ], "evidence": [ { "id": "R-GGA-1855218", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1855218" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XJN9", "gene_name": "SYNJ2", "activity": [ { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "A0A8V0XJN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJN9" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "A0A8V0XJN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJN9" } ] } ] }, { "uniprot_ac": "A0A8V0Y798", "gene_name": "SYNJ1", "activity": [ { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "A0A8V0Y798", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y798" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "A0A8V0Y798", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y798" } ] } ] }, { "uniprot_ac": "A0A8V0YRC1", "gene_name": "OCRL", "activity": [ { "ec_number": "3.1.3.86", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0YRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC1" } ] 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], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267649.30691.1, SRR13267659.300119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Oct 6, 2021 this sequence version replaced XP_040556466.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001383223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383223" } ] }, { "annotation": "CELF1 and CELF2 may underlie conserved, developmentally regulated, tissue-specific processes in vertebrate embryos", "evidence": [ { "database": "RefSeq", "id": "NP_001383223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383223" }, { "database": "PubMed", "id": "23468433", "url": "https://glygen.org/publication/PubMed/23468433" } ] }, { "annotation": "CELF1 is a key regulator of cardiomyocyte gene expression Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001383223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383223" }, { "database": "PubMed", "id": "26866591", "url": "https://glygen.org/publication/PubMed/26866591" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { 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"id": "F1ND14", "url": "https://www.orthodb.org/?gene=F1ND14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001383223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383223", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZM40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZM40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ND14", "url": "https://www.uniprot.org/uniprotkb/F1ND14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1ND14-1", "url": "https://www.uniprot.org/uniprotkb/F1ND14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGTLDHPDQPDLDAIKMFVGQVPRSWCEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKILPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPIVVKFADTQKDKEQKRIAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTAAASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTAALTSSSSPLSVLTSSAGSSPSSSSSSSVNPMASLGALQTLAGATAGLNVSSLAGMAALNGGLGSGGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQSLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 489, "header": "tr|A0A8V0ZNV2-1|A0A8V0ZNV2_CHICK Isoform 1 of CUGBP Elav-like family member 1 OS=Gallus gallus OX=9031 GN=CELF1 PE=3 SV=1 CANONICAL=A0A8V0ZNV2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZM01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2/entry#A0A8V0ZM01-1", "sequence": { "sequence": "MLSNLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKILPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPIVVKFADTQKDKEQKRIAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTAAASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTAALTSSSSPLSVLTSSAGSSPSSSSSSSVNPMASLGALQTLAGATAGLNVSSLAGMAALNGGLGSGGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQSLLTQQSIGAAGSQKEEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 460, "header": "tr|A0A8V0ZM01-1|A0A8V0ZNV2_CHICK Computationally mapped isoform of CUGBP Elav-like family member 1 OS=Gallus gallus OX=9031 GN=CELF1 PE=3 SV=1 CANONICAL=A0A8V0ZNV2-1" }, "locus": { "chromosome": "5", "start_pos": 22380952, "end_pos": 22364273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053918.1", "url": "https://www.ensembl.org/id/ENSGALT00010053918.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032470.1", "url": "https://www.ensembl.org/id/ENSGALP00010032470.1" } ] } }, { "isoform_ac": "A0A8V0ZM40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2/entry#A0A8V0ZM40-1", "sequence": { "sequence": "MNGTLDHPDQPDLDAIKMFVGQVPRSWCEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKILPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPIVVKFADTQKDKEQKRIAQQLQQQMQQISAASVWGNLAGLNTLGPQYLAKLYILHCVAGLNAMQLQNLAALAAAASAAQNTPSGTAALTSSSSPLSVLTSSGKRLHLYYFFLITGMAALNGGLGSGGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQSLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 446, "header": "tr|A0A8V0ZM40-1|A0A8V0ZNV2_CHICK Computationally mapped isoform of CUGBP Elav-like family member 1 OS=Gallus gallus OX=9031 GN=CELF1 PE=3 SV=1 CANONICAL=A0A8V0ZNV2-1" }, "locus": { "chromosome": "5", "start_pos": 22380952, "end_pos": 22364233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053967.1", "url": "https://www.ensembl.org/id/ENSGALT00010053967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032505.1", "url": "https://www.ensembl.org/id/ENSGALP00010032505.1" } ] } }, { "isoform_ac": "A0A8V0ZNV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2/entry#A0A8V0ZNV2-1", "sequence": { "sequence": "MNGTLDHPDQPDLDAIKMFVGQVPRSWCEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKILPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPIVVKFADTQKDKEQKRIAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTAAASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTAALTSSSSPLSVLTSSAGSSPSSSSSSSVNPMASLGALQTLAGATAGLNVSSLAGMAALNGGLGSGGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQSLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 489, "header": "tr|A0A8V0ZNV2-1|A0A8V0ZNV2_CHICK Isoform 1 of CUGBP Elav-like family member 1 OS=Gallus gallus OX=9031 GN=CELF1 PE=3 SV=1 CANONICAL=A0A8V0ZNV2-1" }, "locus": { "chromosome": "5", "start_pos": 22380952, "end_pos": 22364233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053947.1", "url": "https://www.ensembl.org/id/ENSGALT00010053947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032492.1", "url": "https://www.ensembl.org/id/ENSGALP00010032492.1" } ] } }, { "isoform_ac": "F1ND14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2/entry#F1ND14-1", "sequence": { "sequence": "MNGTLDHPDQPDLDAIKMFVGQVPRSWCEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKILPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCNENDIRVMFSPFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPIVVKFADTQKDKEQKRIAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALLQQTAAASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTAALTSSSSPLSVLTSSAGSSPSSSSSSSVNPMASLGALQTLAGATAGLNVSSLAGMAALNGGLGSGGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQSLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 485, "header": "tr|F1ND14-1|A0A8V0ZNV2_CHICK Computationally mapped isoform of CUGBP Elav-like family member 1 OS=Gallus gallus OX=9031 GN=CELF1 PE=3 SV=3 CANONICAL=A0A8V0ZNV2-1" }, "locus": { "chromosome": "5", "start_pos": 22380952, "end_pos": 22364233, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053956.1", "url": "https://www.ensembl.org/id/ENSGALT00010053956.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032499.1", "url": "https://www.ensembl.org/id/ENSGALP00010032499.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Diversity and conservation of CELF1 and CELF2 RNA and protein expression patterns during embryonic development.", "journal": "Developmental dynamics : an official publication of the American Association of Anatomists", "date": "2013", "authors": "Blech-Hermoni Y, Stillwagon SJ, Ladd AN", "evidence": [ { "database": "RefSeq", "id": "NP_001383223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383223" } ], "reference": [ { "type": "PubMed", "id": "23468433", "url": "https://glygen.org/publication/PubMed/23468433" } ] }, { "title": "Identification of Targets of CUG-BP, Elav-Like Family Member 1 (CELF1) Regulation in Embryonic Heart Muscle.", "journal": "PloS one", "date": "2016", "authors": "Blech-Hermoni Yotam, Dasgupta Twishasri, Coram Ryan J, Ladd Andrea N", "evidence": [ { "database": "RefSeq", "id": "NP_001383223", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001383223" } ], "reference": [ { "type": "PubMed", "id": "26866591", "url": "https://glygen.org/publication/PubMed/26866591" } ] } ], "pathway": [ { "id": "gga:373923", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:373923", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2" } ], "pmid": "" }, { "name": "translation initiation factor binding", "id": "GO:0031369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031369", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2" } ], "pmid": "" }, { "name": "lncRNA binding", "id": "GO:0106222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ 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"evidence": [ { "id": "A0A8V0ZN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35/entry#names_and_taxonomy" } ] }, { "name": "2.7.4.3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35/entry#names_and_taxonomy" } ] }, { "name": "ATP-AMP transphosphorylase 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Also displays broad nucleoside diphosphate kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35#function" }, { "database": "UniProtKB", "id": "ARBA00053658", "url": "https://www.uniprot.org/uniprotkb/ARBA00053658#function" }, { "database": "UniProtKB", "id": "A0A8V0ZN63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN63#function" }, { "database": "UniProtKB", "id": "A0A8V0ZVI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVI1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AK5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35", "locus": { "chromosome": "8", "start_pos": 18768919, "end_pos": 18855360, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022373", "url": "https://www.ensembl.org/id/ENSGALG00010022373" } ] } } ], "crossref": [ { "id": "A0A8V0ZN35", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZN35", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01428", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01428", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22978", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22978", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424555", "url": "https://www.ncbi.nlm.nih.gov/gene/424555", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000850", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000850", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424555", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424555", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETHIVHQ", "url": "https://omabrowser.org/oma/group/ETHIVHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN35", "url": "https://www.orthodb.org/?gene=A0A8V0ZN35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN63", "url": "https://www.orthodb.org/?gene=A0A8V0ZN63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVI1", "url": "https://www.orthodb.org/?gene=A0A8V0ZVI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23359", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23359", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00406", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00406", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-499943", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-499943", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "12973", "url": "https://www.rhea-db.org/rhea/12973", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "18113", "url": "https://www.rhea-db.org/rhea/18113", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "44640", "url": "https://www.rhea-db.org/rhea/44640", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZN35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGHRAWLHSADTLKMGMLEQEMQIKLFFYTGVRLVLAIYSNGAHLQKYMASCCGRSLLNGLMCYKPDDPIEYLESCLQKVKELGGSEKVKWDTFVSPEKKALPPLNGGQSRRSFFRNVMPDNSNFPYRRYDRLPPIQQFSIESDTDLSETAELIEEYDVFDPARPRPKIILVIGGPGSGKGTQSLKIAERYGFNYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQRLMQIPDEEGIVIDGFPRDVAQAISFEDQICTPDLVVFLACSNQRLKERLLKRAEQQGRPDDNLKATQRRLMNFKQNAVPLVKYFQEKGLIVTFDADRDEEEVFSDISSAVDNKLFANKEAAAGTNELDCSLIMDSGDTAYTEFDFEDQEEDQSSFSGYESTGDFSEDLKKSNIFFIVGGPGSGKSSQCEQLAKKYGFTHLSTANLLQNELSSLSERSKFIKDIMECGEPVPGGIVLELLKEAMITNLGDTKGFLIDGYPCELKEAEEFESKIGEPKLVFCLDCSAETMNSRYLMRNQTSQHFDSAETIKEGIEGYCQAAKPLTAYYERKTQLCKVDAEGTAEDVFLDVCKSIDSFLKKEEAAFSTETQ", "length": 609, "header": "tr|A0A8V0ZN35-1|A0A8V0ZN35_CHICK Isoform 1 of Adenylate kinase isoenzyme 5 OS=Gallus gallus OX=9031 GN=AK5 PE=3 SV=1 CANONICAL=A0A8V0ZN35-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZN35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35/entry#A0A8V0ZN35-1", "sequence": { "sequence": "MTGHRAWLHSADTLKMGMLEQEMQIKLFFYTGVRLVLAIYSNGAHLQKYMASCCGRSLLNGLMCYKPDDPIEYLESCLQKVKELGGSEKVKWDTFVSPEKKALPPLNGGQSRRSFFRNVMPDNSNFPYRRYDRLPPIQQFSIESDTDLSETAELIEEYDVFDPARPRPKIILVIGGPGSGKGTQSLKIAERYGFNYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQRLMQIPDEEGIVIDGFPRDVAQAISFEDQICTPDLVVFLACSNQRLKERLLKRAEQQGRPDDNLKATQRRLMNFKQNAVPLVKYFQEKGLIVTFDADRDEEEVFSDISSAVDNKLFANKEAAAGTNELDCSLIMDSGDTAYTEFDFEDQEEDQSSFSGYESTGDFSEDLKKSNIFFIVGGPGSGKSSQCEQLAKKYGFTHLSTANLLQNELSSLSERSKFIKDIMECGEPVPGGIVLELLKEAMITNLGDTKGFLIDGYPCELKEAEEFESKIGEPKLVFCLDCSAETMNSRYLMRNQTSQHFDSAETIKEGIEGYCQAAKPLTAYYERKTQLCKVDAEGTAEDVFLDVCKSIDSFLKKEEAAFSTETQ", "length": 609, "header": "tr|A0A8V0ZN35-1|A0A8V0ZN35_CHICK Isoform 1 of Adenylate kinase isoenzyme 5 OS=Gallus gallus OX=9031 GN=AK5 PE=3 SV=1 CANONICAL=A0A8V0ZN35-1" }, "locus": { "chromosome": "8", "start_pos": 18854736, "end_pos": 18770184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054423.1", "url": "https://www.ensembl.org/id/ENSGALT00010054423.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032874.1", "url": "https://www.ensembl.org/id/ENSGALP00010032874.1" } ] } }, { "isoform_ac": "A0A8V0ZN63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35/entry#A0A8V0ZN63-1", "sequence": { "sequence": "MSAGEAKEYLARREIPQLFESLLNGLMCYKPDDPIEYLESCLQKVKELGGSEKVKWDTFVSPEKKALPPLNGGQSRRSFFRNVMPDNSNFPYRRYDRLPPIQQFSIESDTDLSETAELIEEYDVFDPARPRPKIILVIGGPGSGKGTQSLKIAERYGFNYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQRLMQIPDEEGIVIDGFPRDVAQAISFEDQICTPDLVVFLACSNQRLKERLLKRAEQQGRPDDNLKATQRRLMNFKQNAVPLVKYFQEKGLIVTFDADRDEEEVFSDISSAVDNKLFANKEAAAGTNELDCSLIMDSGDTAYTEFDFEDQEEDQSSFSGYESTGDFSEDLKKSNIFFIVGGPGSGKSSQCEQLAKKYGFTHLSTANLLQNELSSLSERSKFIKDIMECGEPVPGGIVLELLKEAMITNLGDTKGFLIDGYPCELKEAEEFESKIGEPKLVFCLDCSAETMNSRYLMRNQTSQHFDSAETIKEGIEGYCQAAKPLTAYYERKTQLCKVDAEGTAEDVFLDVCKSIDSFLKKEEAAFSTETQ", "length": 573, "header": "tr|A0A8V0ZN63-1|A0A8V0ZN63_CHICK Computationally mapped isoform of Adenylate kinase isoenzyme 5 OS=Gallus gallus OX=9031 GN=AK5 PE=3 SV=1 CANONICAL=A0A8V0ZN35-1" }, "locus": { "chromosome": "8", "start_pos": 18855187, "end_pos": 18770184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054459.1", "url": "https://www.ensembl.org/id/ENSGALT00010054459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032899.1", "url": "https://www.ensembl.org/id/ENSGALP00010032899.1" } ] } }, { "isoform_ac": "A0A8V0ZVI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35/entry#A0A8V0ZVI1-1", "sequence": { "sequence": "MSLLNGLMCYKPDDPIEYLESCLQKVKELGGSEKVKWDTFVSPEKKALPPLNGGQSRRSFFRNVMPDNSNFPYRRYDRLPPIQQFSIESDTDLSETAELIEEYDVFDPARPRPKIILVIGGPGSGKGTQSLKIAERYGFNYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQRLMQIPDEEGIVIDGFPRDVAQAISFEDQICTPDLVVFLACSNQRLKERLLKRAEQQGRPDDNLKATQRRLMNFKQNAVPLVKYFQEKGLIVTFDADRDEEEVFSDISSAVDNKLFANKEAAAGTNELDCSLIMDSGDTAYTEFDFEDQEEDQSSFSGYESTGDFSEDLKKSNIFFIVGGPGSGKSSQCEQLAKKYGFTHLSTANLLQNELSSLSERSKFIKDIMECGEPVPGGIVLELLKEAMITNLGDTKGFLIDGYPCELKEAEEFESKIGEPKLVFCLDCSAETMNSRYLMRNQTSQHFDSAETIKEGIEGYCQAAKPLTAYYERKTQLCKVDAEGTAEDVFLDVCKSIDSFLKKEEAAFSTETQ", "length": 554, "header": "tr|A0A8V0ZVI1-1|A0A8V0ZN35_CHICK Computationally mapped isoform of Adenylate kinase isoenzyme 5 OS=Gallus gallus OX=9031 GN=AK5 PE=3 SV=1 CANONICAL=A0A8V0ZN35-1" }, "locus": { "chromosome": "8", "start_pos": 18854892, "end_pos": 18770184, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054411.1", "url": "https://www.ensembl.org/id/ENSGALT00010054411.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032867.1", "url": "https://www.ensembl.org/id/ENSGALP00010032867.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:424555", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424555", "resource": "KEGG Pathway" }, { "id": "R-GGA-499943", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-499943", "resource": "Reactome", "description": "Interconversion of nucleotide di- and triphosphates" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RN95-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "AK5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWTSRVGCRQRPAAVSGNEVQARGGGMLSPASLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQMPDEVGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDSKLFPNKEAAAGSSDLDPSIMLDTGEIIDTGSDYEDQSIFLASNFSYSYFKGFMEELRKCKIIFMIGGPGSGKGTQCEKLGEKYGLTHLSTDKLLRNELSSESERSKLIRDVMERGELVPSGIILELLKEAMVANLSNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRRQSSPCADEDTTTIAKRLETYYRASIPVVAYYETKTQLHKINAEGTPEEVFLQLCSAIDSIF", "length": 573 }, "evidence": [ { "id": "A0A8V0ZN35", "url": "https://omabrowser.org/oma/group/A0A8V0ZN35/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A4IFD0-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "Ak5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNTNEAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQMPDEVGIVIDGFPRDVAQALSFEDQICTPDLVVFLACTNQRLKERLLKRAEQQGRPDDNLKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDSKLFPNKEAAAGSSDLDPSMMLDTGEVIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLKKCKIIFMIGGPGSGKGTQCGKLAEKYGFTHLSTDELLQNELSSESGRSKLIRDIMERGELVPSGIILELLKEAMVASLSNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRSRNSPQADDNTTTIAKRLETYYRASIPVVAYYETKTQLHKINAEGTPEEVFLQLCTAIDSIF", "length": 562 }, "evidence": [ { "id": "A0A8V0ZN35", "url": "https://omabrowser.org/oma/group/A0A8V0ZN35/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A5PMF1-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "ak5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNTNDAKEYLSRREIPQLFESLLTGLMYYRPDDPLEYLETCLKKVRDLGGTDKVRWDTFVGQEKKSLPPLNGGQSRRSFFRNVLPDSPNFPYRRYERLPPINQFSIESDSDLSETAELIEEYEVFDPSRPRPKVILIIGGPGSGKGTQCLKIAERYGFEYVSVGELLRKKMIHNATSNRKWSLIARIITNGELAPQETTITEIKQKIMKIPEASGIVIDGFPRDVGQALSFEDQVCTPDLVVFLACSNQRLKERLEKRAEQQGRPDDNPKAIDRRLTNFKQNAIPLVKYFQEKGLIVTLDADRDEEEVFYDISMTVDNKLFPTKEPVAGPSELDLSLIADSSSLTDVPAKFDEQADEEVAEYAEAIGESFPMETKKSKVIFVIGGPGSGKALQSEKIEERYSLKRLCPGDILCSELQSHSERGRFLRDLLERGEQLPEDTLLDLLCEAMASTVRQGKGFLVTGFPKNEKQAQEYEAKMGQPDIVLLLECSADIMSRRLQQRATCSLHSKEARDRDTRRRVDGFCSLINPVVAHYQHREFFHKIDAEQPPEDVFEHICVVLDSC", "length": 563 }, "evidence": [ { "id": "A0A8V0ZN35", "url": "https://omabrowser.org/oma/group/A0A8V0ZN35/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R7U1-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "Ak5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTNEAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPSRPRPKIILVIGGPGSGKGTQSLKIAERYGFQCISVGELLRKKIHSASSNRKWSLIAKIITNGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISMAVDNKLFPNKEAPTDSSDLDPSMMFDAGEIVDTGSDYDNQDDDQLNVFGEDTMGGFVEDLRKCKIIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGEPQLVICMDCSADTMTNRLLQRSQSSQRGEDSAKSVAKRLEAYHRASIPVIAYYETKTQLQKVNAEGTPDQVFLQLCTAIDSVF", "length": 562 }, "evidence": [ { "id": "A0A8V0ZN35", "url": "https://omabrowser.org/oma/group/A0A8V0ZN35/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q920P5-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "Ak5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTNDAKEYLARRDIPQLFESLLNGLMCSKPEDPIEYLETCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSASSNRKWSLIAKIITNGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLQKRAEQQGRPDDNLKATQRRLVNFKQNAAPLVKYFQEKGLIVTFDADRDEDAVFHDISVAVDSKLFPNKEAPMDSSDLDPSMMFDAGEIIDTGSDYDNQDDDQLNVFGEDTEGGFMEDLRKCKIIFLMGGPGSGKGTQCEKLAEKYGFTHLSTGELLRQELTSESERSKLIRDIMERGDLVPSGVVLELLKEAMVASLGNTKGFLIDGYPREVKQGEEFGRRIGDPHLVICMDCSADTMTNRLLQRSQSSQRGEDGAKSIAKRLEAYHRASIPVVTYYERKTQLRKVNAEGTPEQVFLQLCTAIDSVF", "length": 562 }, "evidence": [ { "id": "A0A8V0ZN35", "url": "https://omabrowser.org/oma/group/A0A8V0ZN35/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y6K8-1", "protein_name": "Adenylate kinase isoenzyme 5", "gene_name": "AK5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNTNDAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF", "length": 562 }, "evidence": [ { "id": "A0A8V0ZN35", "url": "https://omabrowser.org/oma/group/A0A8V0ZN35/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "AMP kinase activity", "id": "GO:0004017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35" } ], "pmid": "" }, { "name": "nucleoside diphosphate kinase activity", "id": "GO:0004550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004550", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "12973", "name": "", "equation": "AMP + ATP = 2 ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Y0A4-1", "A0A8V0Z310-1", "P05081-1", "A0A8V0ZQU1-1", "A0A8V0ZN35-1" ], "evidence": [ { "id": "12973", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/12973" } ] }, { "id": "18113", "name": "", "equation": "a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O57535-1", "A0A8V0ZQU1-1", "A0A8V0Z6S4-1", "Q5ZKE7-1", "P05081-1", "A0A8V0ZN35-1", "A0A8V0XUT9-1", "R4GJC4-1" ], "evidence": [ { "id": "18113", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18113" } ] }, { "id": "44640", "name": "", "equation": "a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "O57535-1", "A0A8V0ZQU1-1", "A0A8V1AL38-1", "A0A8V0XUT9-1", "A0A8V0Z6S4-1", "Q5ZKE7-1", "P05081-1", "A0A8V0ZN35-1", "R4GJC4-1" ], "evidence": [ { "id": "44640", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/44640" } ] }, { "id": "R-GGA-110137", "name": "(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZN35-1" ], "evidence": [ { "id": "R-GGA-110137", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110137" } ] }, { "id": "R-GGA-110138", "name": "AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZN35-1" ], "evidence": [ { "id": "R-GGA-110138", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-110138" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XUT9", "gene_name": "NME6", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0A8V0XUT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUT9" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0A8V0XUT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUT9" } ] } ] }, { "uniprot_ac": "A0A8V0Y0A4", "gene_name": "AK6", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Y0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y0A4" } ] } ] }, { "uniprot_ac": "A0A8V0Z310", "gene_name": "AK2", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0Z310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z310" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0Z310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z310" } ] } ] }, { "uniprot_ac": "A0A8V0Z6S4", "gene_name": "NME3", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0A8V0Z6S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0A8V0Z6S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6S4" } ] } ] }, { "uniprot_ac": "A0A8V0ZN35", "gene_name": "AK5", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "A0A8V0ZN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "A0A8V0ZN35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN35" } ] } ] }, { "uniprot_ac": "A0A8V0ZQU1", "gene_name": "AK4", "activity": [ { "ec_number": "2.7.4.10", "activity": "a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP.", "evidence": [ { "id": "A0A8V0ZQU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU1" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0A8V0ZQU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU1" } ] }, { "ec_number": "2.7.4.10", "activity": "", "evidence": [ { "id": "A0A8V0ZQU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU1" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0A8V0ZQU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU1" } ] } ] }, { "uniprot_ac": "A0A8V1AL38", "gene_name": "NME1", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "A0A8V1AL38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL38" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "A0A8V1AL38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AL38" } ] } ] }, { "uniprot_ac": "O57535", "gene_name": "", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "O57535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O57535" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "O57535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O57535" } ] } ] }, { "uniprot_ac": "P05081", "gene_name": "AK1", "activity": [ { "ec_number": "2.7.4.3", "activity": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "P05081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05081" } ] }, { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "P05081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05081" } ] }, { "ec_number": "2.7.4.4", "activity": "a ribonucleoside 5'-phosphate + ATP = a ribonucleoside 5'-diphosphate + ADP.", "evidence": [ { "id": "P05081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05081" } ] }, { "ec_number": "2.7.4.3", "activity": "", "evidence": [ { "id": "P05081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05081" } ] }, { "ec_number": "2.7.4.4", "activity": "", "evidence": [ { "id": "P05081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05081" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "P05081", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05081" } ] } ] }, { "uniprot_ac": "Q5ZKE7", "gene_name": "CMPK", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "Q5ZKE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKE7" } ] }, { "ec_number": "2.7.4.14", "activity": "UMP + ATP = UDP + ADP.", "evidence": [ { "id": "Q5ZKE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKE7" } ] }, { "ec_number": "2.7.4.14", "activity": "", "evidence": [ { "id": "Q5ZKE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZKE7" } ] } ] }, { "uniprot_ac": "R4GJC4", "gene_name": "CMPK2", "activity": [ { "ec_number": "2.7.4.9", "activity": "dTMP + ATP = dTDP + ADP.", "evidence": [ { "id": "R4GJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ] }, { "ec_number": "2.7.4.14", "activity": "UMP + ATP = UDP + ADP.", "evidence": [ { "id": "R4GJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ] }, { "ec_number": "2.7.4.14", "activity": "", "evidence": [ { "id": "R4GJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ] }, { "ec_number": "2.7.4.9", "activity": "", "evidence": [ { "id": "R4GJC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/R4GJC4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.4.3", "ec_name": "AMP + ATP = 2 ADP.", "evidence": [ { "id": "2.7.4.3", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.4.3" }, { "id": "2.7.4.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.4.3" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 537, "end_pos": 539 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZN40-1", "uniprot_ac": "A0A8V0ZN40", "uniprot_id": "A0A8V0ZN40_CHICK", "mass": { "chemical_mass": 63986.0, "monoisotopic_mass": 63986.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Reverse transcriptase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZN40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN40/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN40" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN40", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZN40", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZN40", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01650", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01650", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33395", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33395", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33395:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33395:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZN40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQMREASCSPVLILTGDFNHPDICWEDHTESCKRSRRLMESIDDNFLVQVLDRPTRGEALLDLLLTNAKEIIKGVHAGGSLGCSDHALVEFVISRDVDLEKSGVRTLNFGRANFKLYNGLLAKIPWDAVLKDKDVEESWLLFKDALLKAQEVSIPLNKKVGRRDRKPAWLGKDLLSTLGAKKGAYKLWKQGCVTWEEYRDAVRTCRRRIRKAKAQVELNLARNVKNNKKTFYRYIGQKRQAKTGVPSLVNLKGELASTDKEKAEVLNEFFASVFTGGQDSSLSHVPEPCTSKPLGGDQGGKSPPTVRAEQVQDRLMRLDEYKSLGPDAVHPRALKELAEVVAKLLSIIFEKLWLSGEVPDDWRKGYVTPIYKKGSKEDPGNYRLVNLTSVPGKIMEQILLDDILDHMRNERVIRDSQHGFTRGRSCLTNLVAFHDGVTALVDEGKATDVIYLDLTKAFDMVTHHILISKLEGCGFDGWTTRWIRNWLKGRRQRVVINGSMSTWRPVTSGVPQGSVLGLVLFNIFINDTDDGIECTLSKFADNTKLSGAVDTEEGRDAIQRELTDLKGGPR", "length": 570, "header": "tr|A0A8V0ZN40-1|A0A8V0ZN40_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZN40-1" }, "isoforms": [ { 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"database": "Ensembl Transcript", "id": "ENSGALT00010054431.1", "url": "https://www.ensembl.org/id/ENSGALT00010054431.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032879.1", "url": "https://www.ensembl.org/id/ENSGALP00010032879.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN40" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion involved in heart morphogenesis", "id": "GO:0061343", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061343", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN40" } ], "pmid": "" }, { "name": "larval heart development", "id": "GO:0007508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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{ "uniprot_canonical_ac": "A0A8V0ZN62-1", "uniprot_ac": "A0A8V0ZN62", "uniprot_id": "A0A8V0ZN62_CHICK", "mass": { "chemical_mass": 36492.0, "monoisotopic_mass": 36492.0 }, "refseq": {}, "gene_names": [ { "name": "CABP2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62" } ] } ], "protein_names": [ { "name": "Calcium binding protein 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CABP2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62", "locus": { "chromosome": "5", "start_pos": 608095, "end_pos": 604498, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021938", "url": "https://www.ensembl.org/id/ENSGALG00010021938" } ] } } ], "crossref": [ { "id": "A0A8V0ZN62", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZN62", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN56", "url": "https://www.orthodb.org/?gene=A0A8V0ZN56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN62", "url": "https://www.orthodb.org/?gene=A0A8V0ZN62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45917", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45917", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45917:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45917:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZN56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLFIRSPQRRAPGSPLPSPCRGPPGVKRGHRNPRGRRSSGGGRRSTEEPQLPLTSRQDGKQRSGPPGPQDGEELAEAAQSPPLQSYSVLHGLVGPACIFLRQSIAITQLDRELRPEEIEELKQAFKEFDKDRDGYISYKDLGECMRTMGYMPTEMELIELSQQITGGKVDFDDFVELMGPKMLAETADMIGIKELRDAFREVRVRHQRGRADQHGGAAGGHAEAAGAAAQLPRGGRDPQGRGSQRGRPGGLRRVCADDVALKGREPPPCLTGRRRRRASPGLRCPSGGWGRAPVVAPPGVVGWQLCRFPMKLCAVGWLCARPLSAGGGLGPSRWG", "length": 336, "header": "tr|A0A8V0ZN62-1|A0A8V0ZN62_CHICK Isoform 1 of Calcium binding protein 2 OS=Gallus gallus OX=9031 GN=CABP2 PE=4 SV=1 CANONICAL=A0A8V0ZN62-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZN56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62/entry#A0A8V0ZN56-1", "sequence": { "sequence": "MFLFIRSPQRRAPGSPLPSPCRGPPGVKRGHRNPRGRRSSGGGRRSTEEPQLPLTSRQSGGPPGLRQAAPRGGPVMPGHPQAMGNCTKTPERRLSKDGKQRSGPPGPQDGEELAEAAQSPPLQSYSVLHGLVGPACIFLRQSIAITQLDRELRPEEIEELKQAFKEFDKDRDGYISYKDLGECMRTMGYMPTEMELIELSQQITGGKVDFDDFVELMGPKMLAETADMIGIKELRDAFREFDTNGDGQISMAELREAMRKLLGQQLNYREVDEILKDVDLNGDGLVDFEEFVRMMSR", "length": 297, "header": "tr|A0A8V0ZN56-1|A0A8V0ZN62_CHICK Computationally mapped isoform of Calcium binding protein 2 OS=Gallus gallus OX=9031 GN=CABP2 PE=4 SV=1 CANONICAL=A0A8V0ZN62-1" }, "locus": { "chromosome": "5", "start_pos": 607654, "end_pos": 604697, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053325.1", "url": "https://www.ensembl.org/id/ENSGALT00010053325.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032137.1", "url": "https://www.ensembl.org/id/ENSGALP00010032137.1" } ] } }, { "isoform_ac": "A0A8V0ZN62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62/entry#A0A8V0ZN62-1", "sequence": { "sequence": "MFLFIRSPQRRAPGSPLPSPCRGPPGVKRGHRNPRGRRSSGGGRRSTEEPQLPLTSRQDGKQRSGPPGPQDGEELAEAAQSPPLQSYSVLHGLVGPACIFLRQSIAITQLDRELRPEEIEELKQAFKEFDKDRDGYISYKDLGECMRTMGYMPTEMELIELSQQITGGKVDFDDFVELMGPKMLAETADMIGIKELRDAFREVRVRHQRGRADQHGGAAGGHAEAAGAAAQLPRGGRDPQGRGSQRGRPGGLRRVCADDVALKGREPPPCLTGRRRRRASPGLRCPSGGWGRAPVVAPPGVVGWQLCRFPMKLCAVGWLCARPLSAGGGLGPSRWG", "length": 336, "header": "tr|A0A8V0ZN62-1|A0A8V0ZN62_CHICK Isoform 1 of Calcium binding protein 2 OS=Gallus gallus OX=9031 GN=CABP2 PE=4 SV=1 CANONICAL=A0A8V0ZN62-1" }, "locus": { "chromosome": "5", "start_pos": 607878, "end_pos": 604697, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053332.1", "url": "https://www.ensembl.org/id/ENSGALT00010053332.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032142.1", "url": "https://www.ensembl.org/id/ENSGALP00010032142.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62" } ], "pmid": "" }, { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62" } ], "pmid": "" }, { "name": "phototransduction", "id": "GO:0007602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007602", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN62", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZN62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN62" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 152, "start_aa": "Glu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZN75-1", "uniprot_ac": "A0A8V0ZN75", "uniprot_id": "A0A8V0ZN75_CHICK", "mass": { "chemical_mass": 105459.0, "monoisotopic_mass": 105459.0 }, "refseq": { "ac": "XP_004942347", "name": "coiled-coil domain-containing protein 186", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942347" }, "gene_names": [ { "name": "CCDC186", "type": "recommended", "evidence": [ { "id": "A0A8V0ZN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN75" } ] }, { "name": "CCDC186", "type": "synonym", "evidence": [ { "id": "XP_004942347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942347" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 186", "type": "synonym", "evidence": [ { "id": "A0A8V0ZN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN75/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 186", "type": "synonym", "evidence": [ { "id": "XP_004942347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942347" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004942347.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942347" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN75" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC186", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN75", "locus": { "chromosome": "6", "start_pos": 28467390, "end_pos": 28499613, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022416", "url": "https://www.ensembl.org/id/ENSGALG00010022416" } ] } } ], "crossref": [ { "id": "A0A8V0ZN75", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZN75", "database": "AlphaFoldDB", "categories": [] }, { "id": "423905", "url": "https://www.ncbi.nlm.nih.gov/gene/423905", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038830", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038830", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423905", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423905", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TLSNGMC", "url": "https://omabrowser.org/oma/group/TLSNGMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN75", "url": "https://www.orthodb.org/?gene=A0A8V0ZN75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18911:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18911:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27942", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27942", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942347", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEEYSPGMQSTLEPVGLSEEASYHSSDSKKSCETSGMKDCSSISCTGDDVGVLEAEPRLLSSDRDSAAADMSGGGGLTERQEQQCAPLDHSEGQDCGANTCSEIRVEGSMETGCLSKEEFGQDPKTNQTEQSLIELLQELREESDLVRKSGDKIYSESPYDTDCTKKLISTIQQTSSQEDLLKEIESELLSTDFSKECKCPNGVRKGEHALAVFDKCVQDKYLQQEQTIKKLIKENKKHQELILEICSEKDNLKDELKKRSETEKQHLNIIKQLEARIEELNKEVKANKDKLVAQDAAAKNAIQQLHKEMAFRMEQANKKCEEARHEKETMVMKYVRGEKESLDLRKEKEILERRVRDANKEIEKHTNKIKQLSQEKGRLHQLYETKDAEATRLNKEIEKLKEEINSHIIKVKWAQNKLKTEMDSHKESKERLKDATTKLTQAKEEADQIRKNCQEMIKTYQESEEIKSNELDAKFKVTKGELEKQMQEKSDQLEVPHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKTEIQSLLDRVKTVDRLQDQHQRDEQDISALKEEVDGLNSLIADLQKDIEGSRKRESELLIFTEKLTSKNAQLQSENNSLQSQLDKLSYSERELQNQLECVQQAKDDLATKLQKEEDQRKLEVEMLQAQLASEQKELTALKTHVDELKDELTTQKRKHAANLKDLSKQLQLARRKLDQIENGNYDKEVSSMGSRSSSSGSLNARSGNEDRSPENTGSSVAVDSFPEVDKSVLVERILRLQKAHARKNEKMEFMEDHIKHLVEEIRKKTKIIQSYILREEAGALSSEASDFNKVHLSRRGGIMASLYTSHPADSGLTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHKHELEQKIKQT", "length": 919, "header": "tr|A0A8V0ZN75-1|A0A8V0ZN75_CHICK Isoform 1 of Coiled-coil domain containing 186 OS=Gallus gallus OX=9031 GN=CCDC186 PE=1 SV=1 CANONICAL=A0A8V0ZN75-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZN75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN75/entry#A0A8V0ZN75-1", "sequence": { "sequence": "MMEEYSPGMQSTLEPVGLSEEASYHSSDSKKSCETSGMKDCSSISCTGDDVGVLEAEPRLLSSDRDSAAADMSGGGGLTERQEQQCAPLDHSEGQDCGANTCSEIRVEGSMETGCLSKEEFGQDPKTNQTEQSLIELLQELREESDLVRKSGDKIYSESPYDTDCTKKLISTIQQTSSQEDLLKEIESELLSTDFSKECKCPNGVRKGEHALAVFDKCVQDKYLQQEQTIKKLIKENKKHQELILEICSEKDNLKDELKKRSETEKQHLNIIKQLEARIEELNKEVKANKDKLVAQDAAAKNAIQQLHKEMAFRMEQANKKCEEARHEKETMVMKYVRGEKESLDLRKEKEILERRVRDANKEIEKHTNKIKQLSQEKGRLHQLYETKDAEATRLNKEIEKLKEEINSHIIKVKWAQNKLKTEMDSHKESKERLKDATTKLTQAKEEADQIRKNCQEMIKTYQESEEIKSNELDAKFKVTKGELEKQMQEKSDQLEVPHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKTEIQSLLDRVKTVDRLQDQHQRDEQDISALKEEVDGLNSLIADLQKDIEGSRKRESELLIFTEKLTSKNAQLQSENNSLQSQLDKLSYSERELQNQLECVQQAKDDLATKLQKEEDQRKLEVEMLQAQLASEQKELTALKTHVDELKDELTTQKRKHAANLKDLSKQLQLARRKLDQIENGNYDKEVSSMGSRSSSSGSLNARSGNEDRSPENTGSSVAVDSFPEVDKSVLVERILRLQKAHARKNEKMEFMEDHIKHLVEEIRKKTKIIQSYILREEAGALSSEASDFNKVHLSRRGGIMASLYTSHPADSGLTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHKHELEQKIKQT", "length": 919, "header": "tr|A0A8V0ZN75-1|A0A8V0ZN75_CHICK Isoform 1 of Coiled-coil domain containing 186 OS=Gallus gallus OX=9031 GN=CCDC186 PE=1 SV=1 CANONICAL=A0A8V0ZN75-1" }, "locus": { "chromosome": "6", "start_pos": 28488227, "end_pos": 28471245, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054477.1", "url": "https://www.ensembl.org/id/ENSGALT00010054477.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032909.1", "url": "https://www.ensembl.org/id/ENSGALP00010032909.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423905", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423905", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MFA7-1", "protein_name": "Coiled-coil domain containing 186", "gene_name": "CCDC186", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSETEHIASISSDQNIEKTSETKEGSCNSSSGDESSSLENESKLLSLNLDKTLCQPNEHNNQTETQENYIPDHGGGKDSCAKTDTGPESSEQIASFPGGDFTKQVLKTSEAEQTVTQILAELRSSTFTAAGNQKTYSESPYDTDCTKKLISKIKNVSTSEDLLEEIESELLSTEFAKEHRVPNGMNKGENALIMFEKCVQDKYLQQEHTIKKLIKENKKHQELILDICSEKDNLREELKKRTETEKQHMNTIKQLETRIEELNKEVQASKDKVLAQDIAAKNAIQQLHKEMAHRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKEMLEKKLRDANKECEKNTNKIKQLSQEKGRLHQLYETKEGEATRLIREIDKLKEDINSHIIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKIADQIQEQHQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTEKLTSKNAQLQSESNSLQSQFDKLSCSESQLQSQCEHMKQTNMNLESRLLKEEELRKEEVQALQAELTCRQTEVKALSTQVEELKDELVTQRRKHASSVKDLTKQLQQARRKLDQVENGSCDKEVSSMGSRSSSSGSLNARSSAEDRSPENTGSSVAVDNFPEVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTNVLFYRIIQSYILREESGTLSSEASDFNKVHLSRRGGIMASLYTSHPADTGLTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHELEQRTKKT", "length": 904 }, "evidence": [ { "id": "A0A8V0ZN75", "url": "https://omabrowser.org/oma/group/A0A8V0ZN75/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7Z3E2-1", "protein_name": "Coiled-coil domain-containing protein 186", "gene_name": "CCDC186", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSETDHIASTSSDKNVGKTPELKEDSCNLFSGNESSKLENESKLLSLNTDKTLCQPNEHNNRIEAQENYIPDHGGGEDSCAKTDTGSENSEQIANFPSGNFAKHISKTNETEQKVTQILVELRSSTFPESANEKTYSESPYDTDCTKKFISKIKSVSASEDLLEEIESELLSTEFAEHRVPNGMNKGEHALVLFEKCVQDKYLQQEHIIKKLIKENKKHQELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNARSSAEDRSPENTGSSVAVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYILREESGTLSSEASDFNKVHLSRRGGIMASLYTSHPADNGLTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHELEQRTKKT", "length": 898 }, "evidence": [ { "id": "A0A8V0ZN75", "url": "https://omabrowser.org/oma/group/A0A8V0ZN75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C9S4-1", "protein_name": "Coiled-coil domain-containing protein 186", "gene_name": "Ccdc186", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIRSRFEEMQSELVPVSMSETEHIASISSDATTEKTSELRDDSCISVSGDESSRLETGAELLSLDSDRILCQTNEHCSQIEVQESHIPDCGSGENSCANTDTCPEDSGQIDDFPGGDFTEQVSKTKEPEQTVTQILAELKSSAPAEAANPKTASASLYDTDCTRKLISEMKTVSASDDLLGEIESELLSAEFAEGHQVPNGLNKGEQALALFEKCVHSRYLQQELTVKQLIKENKNHQELILNICSEKDSLREELRKRTETEKQHMNTIKQLELRIEELNKEIKASKDQLVAQDVTAKNAIQQIHKEMAQRMDQANKKCEEARQEKEAMVMKYVRGEKEALDLRKEKETLERKLRDASKELEKNTNKIKQLSQEKGRLQQLYESKEGETTRLIREIEKLKEEMNSQVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEAEQIRQNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKAKCLEDERLRTEDELSKYREIINRQKSEIQNLLDKVKITDQLHEQLQSGKQEIEHLKEEMESLNSLINDLQKDIEGSRKRESELLLFTEKLTSKNAQLQSESSALQSQVDNLSCTESQLQSQCQQMGQANRNLESKLLKEEELRKEEVQTLQAELSAAQTEVKALSTQVEELKDELVTQRRKHASNVKDLSKQLQQARRKLEQTENGNHDKDISSMGSRSSSSGSLNARISAEDRSPENTSSSVAVDNFPEVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYVLREESGTLSSEASDFNKVHLSRRGGIMASLYTSHPADSGLTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHELEQRTKKA", "length": 917 }, "evidence": [ { "id": "A0A8V0ZN75", "url": "https://omabrowser.org/oma/group/A0A8V0ZN75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle cytoskeletal trafficking", "id": "GO:0099518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099518", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 888, "end_pos": 890 } ] }, 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"id": "XP_426573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426573" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_426573.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_426573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426573" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN76" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DFNB59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN76", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZN76", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZN76", "database": "AlphaFoldDB", "categories": [] }, { "id": "429015", "url": "https://www.ncbi.nlm.nih.gov/gene/429015", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IMNDVGF", "url": "https://omabrowser.org/oma/group/IMNDVGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR15207", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15207", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15207:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15207:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_426573", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_426573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN76", "url": 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"MFAAATKSFVKQVGDGGRLVPVPSLSEADKYQPLSLVVKKKRCFLFPRYKFTSTPFTLKDILLGNREISAGISSYQLLNYEDESDVSLYGRRGNHIVSDVGINVTGSDSIAVKASFGVVTKHEVEVSTLLKEITTRKINFDHSLIRQSRSSRKAVLCVVMESIRTTRQCSLSVHAGIRGEAMRFHFMDEQNPKGRDKAIVFPAHTTIAFSVFELFIYLDGAFDLCVTSVSKGGFEREETATFALLYRLRNILFERNRRVMDAISRSQLYLDDLFSDYYDKPLSMSDISLKEGTHIRVNLLNHNIPKGPCILCGMGNFKRETVYGCFQCSVDGQKYVRLHAVPCFDIWHKRMK", "length": 352 }, "evidence": [ { "id": "A0A8V0ZN76", "url": "https://omabrowser.org/oma/group/A0A8V0ZN76/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q0ZLH2-1", "protein_name": "Pejvakin", "gene_name": "Pjvk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZN81-1", "uniprot_ac": "A0A8V0ZN81", "uniprot_id": "A0A8V0ZN81_CHICK", "mass": { "chemical_mass": 90745.0, "monoisotopic_mass": 90745.0 }, "refseq": {}, "gene_names": [ { "name": "HPS4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZN81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81" } ] } ], "protein_names": [ { "name": "HPS4 biosis of lysosomal organelles complex 3 subunit 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZN81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HPS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81", "locus": { "chromosome": "15", "start_pos": 7151847, "end_pos": 7166001, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023555", "url": "https://www.ensembl.org/id/ENSGALG00010023555" } ] } } ], "crossref": [ { "id": "A0A8V0ZN81", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZN81", "database": "AlphaFoldDB", "categories": [] }, { "id": "416907", "url": "https://www.ncbi.nlm.nih.gov/gene/416907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YACCSPV", "url": "https://omabrowser.org/oma/group/YACCSPV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN81", "url": "https://www.orthodb.org/?gene=A0A8V0ZN81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWU8", "url": "https://www.orthodb.org/?gene=A0A8V0ZWU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWV3", "url": "https://www.orthodb.org/?gene=A0A8V0ZWV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14407", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14407", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14407:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14407:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZN81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLETGLYLPLLDSLKAVPNDDHVGQSTDRPVPPQQVVVQCLAAVHHVEQGRRSICAVLALLEGGDGAVIVWSRHGHSLVTWGWDGVLLPRSLGADATPVLPVLPAPALRRPGRRGSSAWAAPVGHRHAWDTDTHGQRCNYFFLYDGSKVKEEGDPTSAGICYFYPSQTLPDQQELLCGQIAGVVHCMTEISGAPPSLIRLKKLKFAVIVDGDYLWVLGCAVDLPDISCRRFLEQLISLFTFYNGPVHQAYMEFSQEELNRLWDRYIEYIQKSTDDLHKIFNSLWNLDKTKVDPLLLLKAALILQTCQRSPHVLAGCIIYKGLIVSTQLPPPLTAKVLLQGSESSGQSEPGSEEQQEPDSPLPQGVRIVPVFLTEDEVSVLQVEWMNRSTTAPASPRGENNVLSSPAVSESTGIHINQDLNDISVLTEQASSTATPEDVVQSGSFANTVPLEGFPKMEARKRSSPTAELSSPGNERSELNRKPSFSSDGHVKELLSPSELRTAQYAQTMDSYLEGFSFPNPYAKEQESQSTQEFIVDSHVEQHSFQSCLADNASPTTCSAAQELSRRKSNEQEKQGTLSQNSVSAESDAAGDSWSLDCPTPVAQSELRSKSQPMAADVQEGLPSAPAENTDCTQSGEQEWPQAGRLAAQGAESDKHCKFTQMSLYVHSIKGLVLTLLAEDHFQDDRSSIEDVYHSSLASLNGLEVHLRETLPKDFLSSAKATYSFTHYDCIQNVLTANVSHPPGPLDRHFLRAATLIHSDFNRLPTVSEVIVRNASTAVYACRNPVQETYFQQLGAPLRNSGAPNPQDSAFSLPNKAKQKLLKHGVNLL", "length": 828, "header": "tr|A0A8V0ZN81-1|A0A8V0ZN81_CHICK Isoform 1 of HPS4 biosis of lysosomal organelles complex 3 subunit 2 OS=Gallus gallus OX=9031 GN=HPS4 PE=4 SV=1 CANONICAL=A0A8V0ZN81-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZN81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81/entry#A0A8V0ZN81-1", "sequence": { "sequence": "MLETGLYLPLLDSLKAVPNDDHVGQSTDRPVPPQQVVVQCLAAVHHVEQGRRSICAVLALLEGGDGAVIVWSRHGHSLVTWGWDGVLLPRSLGADATPVLPVLPAPALRRPGRRGSSAWAAPVGHRHAWDTDTHGQRCNYFFLYDGSKVKEEGDPTSAGICYFYPSQTLPDQQELLCGQIAGVVHCMTEISGAPPSLIRLKKLKFAVIVDGDYLWVLGCAVDLPDISCRRFLEQLISLFTFYNGPVHQAYMEFSQEELNRLWDRYIEYIQKSTDDLHKIFNSLWNLDKTKVDPLLLLKAALILQTCQRSPHVLAGCIIYKGLIVSTQLPPPLTAKVLLQGSESSGQSEPGSEEQQEPDSPLPQGVRIVPVFLTEDEVSVLQVEWMNRSTTAPASPRGENNVLSSPAVSESTGIHINQDLNDISVLTEQASSTATPEDVVQSGSFANTVPLEGFPKMEARKRSSPTAELSSPGNERSELNRKPSFSSDGHVKELLSPSELRTAQYAQTMDSYLEGFSFPNPYAKEQESQSTQEFIVDSHVEQHSFQSCLADNASPTTCSAAQELSRRKSNEQEKQGTLSQNSVSAESDAAGDSWSLDCPTPVAQSELRSKSQPMAADVQEGLPSAPAENTDCTQSGEQEWPQAGRLAAQGAESDKHCKFTQMSLYVHSIKGLVLTLLAEDHFQDDRSSIEDVYHSSLASLNGLEVHLRETLPKDFLSSAKATYSFTHYDCIQNVLTANVSHPPGPLDRHFLRAATLIHSDFNRLPTVSEVIVRNASTAVYACRNPVQETYFQQLGAPLRNSGAPNPQDSAFSLPNKAKQKLLKHGVNLL", "length": 828, "header": "tr|A0A8V0ZN81-1|A0A8V0ZN81_CHICK Isoform 1 of HPS4 biosis of lysosomal organelles complex 3 subunit 2 OS=Gallus gallus OX=9031 GN=HPS4 PE=4 SV=1 CANONICAL=A0A8V0ZN81-1" }, "locus": { "chromosome": "15", "start_pos": 7165802, "end_pos": 7154191, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057349.1", "url": "https://www.ensembl.org/id/ENSGALT00010057349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034858.1", "url": "https://www.ensembl.org/id/ENSGALP00010034858.1" } ] } }, { "isoform_ac": "A0A8V0ZWU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81/entry#A0A8V0ZWU8-1", "sequence": { "sequence": "MARPQQGSASWCNYFFLYDGSKVKEEGDPTSAGICYFYPSQTLPDQQELLCGQIAGVVHCMTEISGAPPSLIRLKKLKFAVIVDGDYLWVLGCAVDLPDISCRRFLEQLISLFTFYNGPVHQAYMEFSQEELNRLWDRYIEYIQKSTDDLHKIFNSLWNLDKTKVDPLLLLKAALILQTCQRSPHVLAGCIIYKGLIVSTQLPPPLTAKVLLQGSESSGQSEPGSEEQQEPDSPLPQGVRIVPVFLTEDEVSVLQVEWMNRSTTAPASPRGENNVLSSPAVSESTGIHINQDLNDISVLTEQASSTATPEDVVQSGSFANTVPLEGFPKMEARKRSSPTAELSSPGNERSELNRKPSFSSDGHVKELLSPSELRTAQYAQTMDSYLEGFSFPNPYAKEQESQSTQEFIVDSHVEQHSFQSCLADNASPTTCSAAQELSRRKSNEQEKQGTLSQNSVSAESDAAGDSWSLDCPTPVAQSELRSKSQPMAADVQEGLPSAPAESDKHCKFTQMSLYVHSIKGLVLTLLAEDHFQDDRSSIEDVYHSSLASLNGLEVHLRETLPKDFLSSAKATYSFTHYDCIQNVLTANVSHPPGPLDRHFLRAATLIHSDFNRLPTVSEVIVRNASTAVYACRNPVQETYFQQLGAPLRNSGAPNPQDSAFSLPNKAKQKLLKHGVNLL", "length": 678, "header": "tr|A0A8V0ZWU8-1|A0A8V0ZN81_CHICK Computationally mapped isoform of HPS4 biosis of lysosomal organelles complex 3 subunit 2 OS=Gallus gallus OX=9031 GN=HPS4 PE=4 SV=1 CANONICAL=A0A8V0ZN81-1" }, "locus": { "chromosome": "15", "start_pos": 7164747, "end_pos": 7154191, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057339.1", "url": "https://www.ensembl.org/id/ENSGALT00010057339.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034851.1", "url": "https://www.ensembl.org/id/ENSGALP00010034851.1" } ] } }, { "isoform_ac": "A0A8V0ZWV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81/entry#A0A8V0ZWV3-1", "sequence": { "sequence": "MEFSQEELNRLWDRYIEYIQKSTDDLHKIFNSLWNLDKTKVDPLLLLKAALILQTCQRSPHVLAGCIIYKGLIVSTQLPPPLTAKVLLQGSESSGQSEPGSEEQQEPDSPLPQGVRIVPVFLTEDEVSVLQVEWMNRSTTAPASPRGENNVLSSPAVSESTGIHINQDLNDISVLTEQASSTATPEDVVQSGSFANTVPLEGFPKMEARKRSSPTAELSSPGNERSELNRKPSFSSDGHVKELLSPSELRTAQYAQTMDSYLEGFSFPNPYAKEQESQSTQEFIVDSHVEQHSFQSCLADNASPTTCSAAQELSRRKSNEQEKQGTLSQNSVSAESDAAGDSWSLDCPTPVAQSELRSKSQPMAADVQEGLPSAPAENTDCTQSGEQEWPQAGRLAAQGAESDKHCKFTQMSLYVHSIKGLVLTLLAEDHFQDDRSSIEDVYHSSLASLNGLEVHLRETLPKDFLSSAKATYSFTHYDCIQNVLTANVSHPPGPLDRHFLRAATLIHSDFNRLPTVSEVIVRNASTAVYACRNPVQETYFQQLGAPLRNSGAPNPQDSAFSLPNKAKQKLLKHGVNLL", "length": 578, "header": "tr|A0A8V0ZWV3-1|A0A8V0ZN81_CHICK Computationally mapped isoform of HPS4 biosis of lysosomal organelles complex 3 subunit 2 OS=Gallus gallus OX=9031 GN=HPS4 PE=4 SV=1 CANONICAL=A0A8V0ZN81-1" }, "locus": { "chromosome": "15", "start_pos": 7162868, "end_pos": 7154191, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057345.1", "url": "https://www.ensembl.org/id/ENSGALT00010057345.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034856.1", "url": "https://www.ensembl.org/id/ENSGALP00010034856.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I8P4-1", "protein_name": "Hermansky-Pudlak syndrome 4 protein isoform X1", "gene_name": "Hps4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MATPTPSEIKSASWWNYFFLYDGSKVKGEGDPTRAGICYFYPSKTLLDQQELLCGQLAGVVRCLWDLSGTPPTLIRLRKLKFAIRVDGDYLWALGCGVELSDVSCRQFLDQLIGFFHFYMGPVSLAYKSRSQEELSLQWDTFITQVLRGTSESHRIFNALWNLDHTKVEPLLLLKAALILQTCQRSPHVLAGCILYKGLIVNSQLPPSLTAKVLLYQTAPEDQRLPGAGAPQQEAGAALPPNVQITPVFLSEEEVASLHEFTVEQKTRLQESSSQYPPWDRSTPTRAEDAWTSATILEPTPHDGAWLNGRGADGHLLGHEQQEHAAAAGLCATACGPGSGSSSSSLQQELGFSQEELDLSEIHISEAQEAFSPAPALGDQEAVFTSHQAPTLPEDTAVCSCLDPSPLERLPESRGLERLTDLPISNGQTQVPGMDPLPRRSSRPAVLPPQDPGAEQYRDGSHEHRSALACTLYSGDSRGPSTPADRIGFAPSPAGPYAGLLPMNLYTHSVNGLVLSLLGEEPLLRDTAAIEEVYHSSLASLNGLEVHLKETLPRDEACPTSSTYSFVHYDRIQSMLTANLSLVAAPQDRRFLQAINLVHSDFAQLPTLYEMTVRNASTAVYACCNPAQETYFQQLTPTTRSSGFPNPQDCAFSLAGKAKRKLLKHGVNLL", "length": 670 }, "evidence": [ { "id": "A0A8V0ZN81", "url": "https://omabrowser.org/oma/group/A0A8V0ZN81/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8J8YPH6-1", "protein_name": "HPS4, biogenesis of lysosomal organelles complex 3 subunit 2", "gene_name": "Hps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFCSLARWNYFFLYDGSKVQGEGDPTRAGICYFYPSQTLLDQQELLCGQLAGVVRCLWDLSGTPPMLIRLRNLKFALRVDGDYLWALGCGVELSDASCRQFLDQLIGFFHFYMGPVSLAYKSHPQEELRLQWDTFITQVLRSTSESHRIFNALWNLDRTKVPTLLLMAFLSVCLTLRIVNSQLPPSLTAKVLLHHTVAADQRPPGAGAATQETGPALPPAVQITPVFLSEEEVASLHEFPVEHDPRLEESSFQCPPWDQSTPTGAEDAWTSATVLEPTPCGGGHSPRLEQERAGPTGLCTEACDRSSDLSGRLQRELCLSQELDLSAMHLSEAQDAFPPVPASCDLQALCVSRDTPTLPEDTAICSCLDPSPLERPPEGGSLEALADLPLTHGHTHVPGTEPLPSSRTMVLLPQHPEGVEPGVEPCGSGAQDRLPALARSSHSADSQGPSPSADRTGFNPSPSGPHAGLMPMNLYTHSVNGLVLSLLAKETLGSDTAAIEEVPTVLSHPPSDAVWTEVRCLHLLGPFQDHAAYPVSGLFIQYHSSLASLNGLEVHLKETLPRDETSPTGSTYNFLHYDRIQSVLSANLPLVAAPQNRRFLQAVNLMHSDFAQLPMLYEMTIRNASTAVYACSNPAQETYFQQLAPTARSSGFPNPQDCAFSLSGKAKQKLLKHGVNLL", "length": 680 }, "evidence": [ { "id": "A0A8V0ZN81", "url": "https://omabrowser.org/oma/group/A0A8V0ZN81/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BLQ1-1", "protein_name": "HPS4 biosis of lysosomal organelles complex 3 subunit 2", "gene_name": "HPS4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAASTSTESKLASWWNYFFLYDGSQVKGEEDPTRAGICYFYPPQTLLDQQELLCGQIAGVVHCVSHISGSPPALVRLRKLKFAVKVDGDYLWVLGCAAELPDVSCRQLLHRLVGFFHFCNGPVSLACKSCPREELRSEWDTLIEHILGNTGDLHKIFNCLWHLDQTKVEALLLLKAALILQTCQRAPHVLAGCILYAGLIVSTQLPPSVTAKVLLHRMARRDQRKPTGGDALQERGVVLPPNVQITPVFLTEEEAASLREFPREPSASAPAPPARLQEPSAAPKENAPGHAGSKAQTSTTTPEPPSPDAALADGSRGHGHWSGPDLKSTPPALQHCTAAGKGSALFVGNGHLDLSEIHIPEAQKTEASPGHPAADGGGPGCEESVHNPGSPEAKPPGVLSLGRLPASAPEVVPQNGALEQPADLPGDGSQAPIPRKDHVPSRTSGPGRAPCLDLRQKNTEQPLEEHGGEQRHSGAPEGCLTPGPDSTDPSDEGPSANRTASRVSPASREGLVRMNLYTHSVKGLVLSLLAEEPLLGDRVAVEEVYHGSLASLNGLEVHLSETLPRDQAAPAARTYSFAHYDRVQNLLTANLPQVTTAQDRRFLQAVSLMHSEFARLPTLYEVTVRNASTAVYACCNPVQETYFQQLATAVRSSGFPNPQDGAFGLPGKAKQKLLKHGVNLL", "length": 681 }, "evidence": [ { "id": "A0A8V0ZN81", "url": "https://omabrowser.org/oma/group/A0A8V0ZN81/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99KG7-1", "protein_name": "BLOC-3 complex member HPS4", "gene_name": "Hps4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTPPETKSAAWWNYFFLYDGSKVKGEGDPTRAGICYFYPPQTLLDQQELLCGQLAGVVRCLWDLSGTPPMLIRMRNLKFAIRADGDYLWALGCGVEISDASCRQFLDQLIGFFHFYMGPVSLAYKSHPQEELSLQWDTSITQVLRSTSESHRIFNALWNLDRTKVEPLLLLKAALILQTCQRSPHVLAGCILYKGLIVNSQLLPSLTAKVLLHQTVPADQRLPGAGAAPQETGAALPPDVQITSVFLSEEEVASLHEFPVEHETRLQGSSVQYPPWDQSSPTQAEDAWASAAIPEPTPHDGACPSGSGADERLPRLEQECAGPTGLCTTACGQGSGLSSRLQKELCLSREELDSSEMHVSEAQEAFPPLPALGDLETLHSSHSAPTLPEDTAICSCLHPCPLERLPESGRLGQLADLPLTNGQTQVPGTDPLPSSMPVALPPQHPVGVEPSVEPYGNGAQESHSALPRSSRSPDSPGPSPSADRTGFKPSPSGRHAGLVPMNLYTHSVNGLVLSLLAEETLLSDTAAIEEVYHSSLASLNGLEVHLKETLPRDEASLTSSTYNFLHYDRIQSVLSANLPLVTAPQDRRFLQAVNLMHSDFALLPMLYEMTIRNASTAVYACSSPAQETYFQQLAPTARSSGFPNPQDCAFSLAGKAKQKLLKHGVNLL", "length": 671 }, "evidence": [ { "id": "A0A8V0ZN81", "url": "https://omabrowser.org/oma/group/A0A8V0ZN81/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQG7-1", "protein_name": "BLOC-3 complex member HPS4", "gene_name": "HPS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGVVRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYNGPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARILQTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALPPNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGHVESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKELVFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDTAISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRGNKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVRMNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSSTYNFTHYDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYACCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL", "length": 708 }, "evidence": [ { "id": "A0A8V0ZN81", "url": "https://omabrowser.org/oma/group/A0A8V0ZN81/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": 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"name": "lysosome organization", "id": "GO:0007040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007040", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZN81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81" }, { "id": "PF19033", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCZ1/INTU/HPS4 third Longin", "eco_id": "ECO_0000259", "start_pos": 720, "end_pos": 819, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZN81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN81" }, { "id": "PF19031", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19031" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCZ1/INTU/HSP4 first Longin", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 244, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEPGKGMILSHNPLSVIDDASFFQLPAVSYLDLGATRVSRLTVLNLLLTAARLEMLRVPRAAACCLCQEGRAAETLCRRVRFQGRELCASSPHCGRLPAPHPAGVGSSVPPDLLPALGGAVLRLRCVSSLLHDPTGTERGLTTRLE", "length": 147, "header": "tr|A0A8V0ZN86-1|A0A8V0ZN86_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZN86-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZN86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN86/entry#A0A8V0ZN86-1", "sequence": { "sequence": "MEEPGKGMILSHNPLSVIDDASFFQLPAVSYLDLGATRVSRLTVLNLLLTAARLEMLRVPRAAACCLCQEGRAAETLCRRVRFQGRELCASSPHCGRLPAPHPAGVGSSVPPDLLPALGGAVLRLRCVSSLLHDPTGTERGLTTRLE", "length": 147, "header": "tr|A0A8V0ZN86-1|A0A8V0ZN86_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZN86-1" }, "locus": { "chromosome": "27", "start_pos": 1258998, "end_pos": 1257621, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057363.1", "url": "https://www.ensembl.org/id/ENSGALT00010057363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034863.1", "url": "https://www.ensembl.org/id/ENSGALP00010034863.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZN92-1", "uniprot_ac": "A0A8V0ZN92", "uniprot_id": "A0A8V0ZN92_CHICK", "mass": { "chemical_mass": 45956.0, "monoisotopic_mass": 45956.0 }, "refseq": { "ac": "XP_024998360", "name": "arylacetamide deacetylase-like 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998360" }, "gene_names": [ { "name": "AADACL4A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZN92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN92" } ] }, { "name": "AADACL4A", "type": "synonym", "evidence": [ { "id": "XP_024998360", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998360" } ] } ], "protein_names": [ { "name": "Alpha/beta hydrolase fold-3 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZN92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN92/entry#names_and_taxonomy" } ] }, { "name": "arylacetamide deacetylase-like 3", "type": "synonym", "evidence": [ { "id": "XP_024998360", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998360" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_024998360.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_024998360", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998360" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN92" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AADACL4A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN92", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZN92", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZN92", "database": "AlphaFoldDB", "categories": [] }, { "id": "768668", "url": "https://www.ncbi.nlm.nih.gov/gene/768668", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:768668", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768668", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PVRMYQP", "url": "https://omabrowser.org/oma/group/PVRMYQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZN92", "url": "https://www.orthodb.org/?gene=A0A8V0ZN92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07859", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07859", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_024998360", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_024998360", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZN92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELFFALTSIAGILLAFLLSVLIEASYHTFKAKIPPEVDQPSKLSFYSWLFTTVEILANKLASLRICKKHVLIRMFSNGMRARRASELLIKDLHFGEVPVRIYLPRSPSASKRRGVVLFHGGCGMYGSIRSHERICQQIAKKSDSVVVSVGYRLSPEHRYPTQSLDCVNATIHFLKTAKSYGVDPHRVILCGDSAGGTFATGTCQELLNRADIPKIRAQILIYPFLQAMNFNLPSHQKNASTGLLSLERTVCFILMYLRKDCALTKAILAGSHVPESMNLKYKKWIHPDLIPEKFKQDYKPPLPASYTPQVHEEMKEMFELRFSPLLAEDAVVGRLPDTCIITCEHDVLRDDGLLYKKRLEDNNVKVTWCHIEDGFHGVLCFLGYGIFSFPSASKIMDHIVNFIEGC", "length": 407, "header": "tr|A0A8V0ZN92-1|A0A8V0ZN92_CHICK Isoform 1 of Alpha/beta hydrolase fold-3 domain-containing protein OS=Gallus gallus OX=9031 GN=AADACL4A PE=3 SV=1 CANONICAL=A0A8V0ZN92-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZN92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN92/entry#A0A8V0ZN92-1", "sequence": { "sequence": "MELFFALTSIAGILLAFLLSVLIEASYHTFKAKIPPEVDQPSKLSFYSWLFTTVEILANKLASLRICKKHVLIRMFSNGMRARRASELLIKDLHFGEVPVRIYLPRSPSASKRRGVVLFHGGCGMYGSIRSHERICQQIAKKSDSVVVSVGYRLSPEHRYPTQSLDCVNATIHFLKTAKSYGVDPHRVILCGDSAGGTFATGTCQELLNRADIPKIRAQILIYPFLQAMNFNLPSHQKNASTGLLSLERTVCFILMYLRKDCALTKAILAGSHVPESMNLKYKKWIHPDLIPEKFKQDYKPPLPASYTPQVHEEMKEMFELRFSPLLAEDAVVGRLPDTCIITCEHDVLRDDGLLYKKRLEDNNVKVTWCHIEDGFHGVLCFLGYGIFSFPSASKIMDHIVNFIEGC", "length": 407, "header": "tr|A0A8V0ZN92-1|A0A8V0ZN92_CHICK Isoform 1 of Alpha/beta hydrolase fold-3 domain-containing protein OS=Gallus gallus OX=9031 GN=AADACL4A PE=3 SV=1 CANONICAL=A0A8V0ZN92-1" }, "locus": { "chromosome": "21", "start_pos": 5300833, "end_pos": 5293775, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010050965.1", "url": "https://www.ensembl.org/id/ENSGALT00010050965.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030156.1", "url": "https://www.ensembl.org/id/ENSGALP00010030156.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:768668", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:768668", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B1AVU7-1", "protein_name": "AADACL4 family member 3", "gene_name": "AAdacl4fm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGFWLVLIGGLLTFFLGVFVWVFIQHLLTIEIPSTLKHPVKLWILHLIFQYLITLGTILEKLRICSMPAILQFFQDLIIIKKKVPNVIVTDTRFGTVPVRLFRPKEVSSKPRRGIIFYHGGGAVCGSLDFYHGLGNVLAHETDSVVLLVGYRKLPDHHHPVVYLDCLNASIHFLKNLQTYGVDPSRVVISGESIGGWTVATVTQALVSQAILPQIRAQVLITPGLQGINFQLPSHQQKQNVPLLTRDLVITFVCRYLSIDLSWKNAIVTGAFVPLDTWKKYSKWLSSDNIPKRFKSKKFHPEFLGPFSETAYLETKHVFDVNISPLLADDKIIAQLPDTFLVSCEHDVLRDDALLYKKRLEDQGVPVSWYHAEDGFHGCISLFDKQPFSFPCSMNVLNAVISYIKDV", "length": 408 }, "evidence": [ { "id": "A0A8V0ZN92", "url": "https://omabrowser.org/oma/group/A0A8V0ZN92/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A340-1", "protein_name": "AADACL4 family member 3 like 1", "gene_name": "Aadacl4fm3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVLWLVLLGGMLTFFLGVFVWAFIQHLLTVEIPSTLKHPVKLRILHFSFQYLINLGTILEKLRICSTPAFLLCIQDLVIIIKKDPNMLVTDTRFGTVPVRLFKPKKVSSKLRRGIIFYHGGGGLFGSLDVYHGLGNFLARETDSVVLLVGYRKLPDHRHPVIHLDCLNASIHFLKNLQTYGVDPSRVVIAGESAGGWAVATVTQALSCQDKLPQIRAQVLITPVLQGVNFQLPSQLQKHNVPLLTRDLMITFICSYLSIDLSWKNAILTGACVPPDMWKKYSKWLSSDNIPQRFKGKDFSPEFLGPFNETAYLETKHILDEKISPLLADDKIIAQLPDTFLLSCEHDILRDDTLLYKKRLEDQGVPVTWHHVEDGFHGCIIFFDNQFFSFPCSMNALNATISYIKGI", "length": 408 }, "evidence": [ { "id": "A0A8V0ZN92", "url": "https://omabrowser.org/oma/group/A0A8V0ZN92/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carboxylic ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZN92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZN92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN92" }, { "id": "PF07859", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07859" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha/beta hydrolase fold-3", "eco_id": "ECO_0000259", "start_pos": 116, "end_pos": 260, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 239, "end_pos": 241 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNA3-1", "uniprot_ac": "A0A8V0ZNA3", "uniprot_id": "A0A8V0ZNA3_CHICK", "mass": { "chemical_mass": 65972.0, "monoisotopic_mass": 65972.0 }, "refseq": {}, "gene_names": [ { "name": "CRY2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA3" } ] } ], "protein_names": [ { "name": "Cryptochrome circadian regulator 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CRY2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA3", "locus": { "chromosome": "5", "start_pos": 23477158, "end_pos": 23497483, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022046", "url": "https://www.ensembl.org/id/ENSGALG00010022046" } ] } } ], "crossref": [ { "id": "A0A8V0ZNA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNA3", "url": "https://www.orthodb.org/?gene=A0A8V0ZNA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11455", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11455", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11455:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11455:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00875", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00875", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZNA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAASPPRGFCRSVHWFRRGLRLHDNPALQAALRGAASLRCIYILDPWFAASSAVGINRWRFLLQSLEDLDNSLRKLNSRLFVVRGQPTDVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIIKLAKEAGVEVVIENSHTLYDLDRIIELNGNKPPLTYKRFQAIISRMELPKKPVSSIVSQQMETCKVDIQENHDDVYGVPSLEELGFPTDGLAPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWELYKKVKRNSTPPLSLYGQLLWREFFYTAATNNPKFDRMEGNPICIQIPWDKNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYVKYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPKPMVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSGPVTDSAPGQGSSTSTAVRLPQSDQASPKRKHEGAEELCTEELYKRAKVTGLPAPEIPGKSS", "length": 581, "header": "tr|A0A8V0ZNA3-1|A0A8V0ZNA3_CHICK Isoform 1 of Cryptochrome circadian regulator 2 OS=Gallus gallus OX=9031 GN=CRY2 PE=3 SV=1 CANONICAL=A0A8V0ZNA3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA3/entry#A0A8V0ZNA3-1", "sequence": { "sequence": "MAAAASPPRGFCRSVHWFRRGLRLHDNPALQAALRGAASLRCIYILDPWFAASSAVGINRWRFLLQSLEDLDNSLRKLNSRLFVVRGQPTDVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIIKLAKEAGVEVVIENSHTLYDLDRIIELNGNKPPLTYKRFQAIISRMELPKKPVSSIVSQQMETCKVDIQENHDDVYGVPSLEELGFPTDGLAPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWELYKKVKRNSTPPLSLYGQLLWREFFYTAATNNPKFDRMEGNPICIQIPWDKNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYVKYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPKPMVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSGPVTDSAPGQGSSTSTAVRLPQSDQASPKRKHEGAEELCTEELYKRAKVTGLPAPEIPGKSS", "length": 581, "header": "tr|A0A8V0ZNA3-1|A0A8V0ZNA3_CHICK Isoform 1 of Cryptochrome circadian regulator 2 OS=Gallus gallus OX=9031 GN=CRY2 PE=3 SV=1 CANONICAL=A0A8V0ZNA3-1" }, "locus": { "chromosome": "5", "start_pos": 23497442, "end_pos": 23479563, "strand": "+", "evidence": [ { "database": 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], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA3" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA3" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNA3" } ], "pmid": "" }, { "name": "response to insulin", "id": "GO:0032868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNA3", "url": 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"ILLYQVTSKGAGLNPNAKVWQEGPQGGGEAAPPSNGTEHSWHEPAAVAGTQTEGNVEISEDGCKHYEVMYSTSCEAARNDTGIDEAAANGIVLTTEDLGYPIYEVAGEGNSVVSTEDIRECLRKQLEFCFSRENLSKDLYLMSQMDSDQFVPIWTIANMEGIKKLTTDMDLILDVLRSSPMVQVDETGEKVRPNHKRCIIILREIPETTPVEEVKALFKNENCPKVISCEFAHNNNWYVTFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTFFAKNGYRVVDSSVYAQPIQTQAQFASPLFMQPVYSPQQYSIYSIVPQTWSPNPAPYFETPLAPFPNGGFVNGFNTPGSYKTSAAALSIGRPFHRNRVKPHFRSSNSSEHAAEGPAAAGTVSLGDGPLSRTNSRNFVMERHNSTLTGHQEQGYSQKDSPTMQMEQNGDYGIGRGRRNIFRGRRRREDDRISRPQPSTETKTQTPKFDLLASNFPPLPGSTAKIPGEPVLESRMSDVVKGISKEKESKDLLLSCPAPAQEEQTPSVVQQPVTSVSPSGQTEAVVLSSAVQPESKPEEVSVQKDVKGHTSPPVSVCPVSAAKPPRTNSTSSPTNTSAAPAVAVQEPRKLSYAEVCQKPPKEPPPVPVQPLRELRTNIVPPAKADDGGTAERASEKAPDKAEGRMKDYCGIRGSGAPVWTQIIASGSAAACRQGAVRATSVTKVTPVRPIPLFNLSCGLMSSKGD", "length": 737, "header": "tr|A0A8V0ZQM9-1|A0A8V0ZQM9_CHICK Computationally mapped isoform of La ribonucleoprotein domain family member 4 OS=Gallus gallus OX=9031 GN=LARP4 PE=1 SV=1 CANONICAL=A0A8V0ZNB6-1" }, "locus": { "chromosome": "34", "start_pos": 394091, "end_pos": 382519, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054539.1", "url": "https://www.ensembl.org/id/ENSGALT00010054539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032945.1", "url": "https://www.ensembl.org/id/ENSGALP00010032945.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB6" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB6" } ], "pmid": "" }, { "name": "poly(A) binding", "id": "GO:0008143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB6" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB6" } ], "pmid": "" }, { "name": "cytosolic small ribosomal subunit", "id": "GO:0022627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022627", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of translation", "id": "GO:0045727", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045727", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 608, "end_pos": 610, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNB6" }, { "id": "PS50961", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50961" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH La-type RNA-binding", "eco_id": "ECO_0000259", "start_pos": 113, "end_pos": 202, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 382, "end_pos": 384 }, { "start_pos": 418, "end_pos": 420 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 608, "end_pos": 610 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNC1-1", "uniprot_ac": "A0A8V0ZNC1", "uniprot_id": "A0A8V0ZNC1_CHICK", "mass": { "chemical_mass": 43348.0, "monoisotopic_mass": 43348.0 }, "refseq": { "ac": "XP_418132", "name": "interferon-induced 35 kDa protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418132" }, "gene_names": [ { "name": "IFI35", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1" } ] }, { "name": "IFI35", "type": "synonym", "evidence": [ { "id": "XP_418132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418132" } ] } ], "protein_names": [ { "name": "Interferon induced protein 35", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1/entry#names_and_taxonomy" } ] }, { "name": "interferon-induced 35 kDa protein", "type": "synonym", "evidence": [ { "id": "XP_418132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418132" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418132" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IFI35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1", "locus": { "chromosome": "27", "start_pos": 5103756, "end_pos": 5100499, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022439", "url": "https://www.ensembl.org/id/ENSGALG00010022439" } ] } } ], "crossref": [ { "id": "A0A8V0ZNC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12545", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12545", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420011", "url": "https://www.ncbi.nlm.nih.gov/gene/420011", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FQKNTNG", "url": "https://omabrowser.org/oma/group/FQKNTNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNC1", "url": "https://www.orthodb.org/?gene=A0A8V0ZNC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQN5", "url": "https://www.orthodb.org/?gene=A0A8V0ZQN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15225", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15225", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15225:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15225:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418132", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQN5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSEEDSFVRLASPQQREDCSPEMSPERARQEIEQYKDLCRALDQDNAMLQKDKEAVEQRLQHVKKERELLQKNLKQKPPKDEKVSLQVDISIAQDEKSRLTQEKQMLENKLEEMRKRILWEDPMMMLRTLPERKVVFKGLTTDKENMDKLVLTPLVRYPLSGGSALITFEKAEVAQRVIEMKEHVVELSHGEDPEDLDRCQVRVQAGPVDILLPSALEIGLTRGSRSILVSGLPSLGIPEDILLDKLELFFSKTKNGGSEVESREFLDDCGQVVLTFTQDGVAEQLITRGQVQVPIGKTKYKLKISPYMSGDVTNLQLQPSHCTRTVLLSGIPDVLAEEPMRDALEIHFQKDSRGGGEVDVLGYVPAGRWAVAVFREDMGQP", "length": 383, "header": "tr|A0A8V0ZNC1-1|A0A8V0ZNC1_CHICK Isoform 1 of Interferon induced protein 35 OS=Gallus gallus OX=9031 GN=IFI35 PE=1 SV=1 CANONICAL=A0A8V0ZNC1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1/entry#A0A8V0ZNC1-1", "sequence": { "sequence": "MDSEEDSFVRLASPQQREDCSPEMSPERARQEIEQYKDLCRALDQDNAMLQKDKEAVEQRLQHVKKERELLQKNLKQKPPKDEKVSLQVDISIAQDEKSRLTQEKQMLENKLEEMRKRILWEDPMMMLRTLPERKVVFKGLTTDKENMDKLVLTPLVRYPLSGGSALITFEKAEVAQRVIEMKEHVVELSHGEDPEDLDRCQVRVQAGPVDILLPSALEIGLTRGSRSILVSGLPSLGIPEDILLDKLELFFSKTKNGGSEVESREFLDDCGQVVLTFTQDGVAEQLITRGQVQVPIGKTKYKLKISPYMSGDVTNLQLQPSHCTRTVLLSGIPDVLAEEPMRDALEIHFQKDSRGGGEVDVLGYVPAGRWAVAVFREDMGQP", "length": 383, "header": "tr|A0A8V0ZNC1-1|A0A8V0ZNC1_CHICK Isoform 1 of Interferon induced protein 35 OS=Gallus gallus OX=9031 GN=IFI35 PE=1 SV=1 CANONICAL=A0A8V0ZNC1-1" }, "locus": { "chromosome": "27", "start_pos": 5103695, "end_pos": 5100636, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054548.1", "url": "https://www.ensembl.org/id/ENSGALT00010054548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032954.1", "url": "https://www.ensembl.org/id/ENSGALP00010032954.1" } ] } }, { "isoform_ac": "A0A8V0ZQN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1/entry#A0A8V0ZQN5-1", "sequence": { "sequence": "MDSEEDSFVRLASPQQREDCSPEMSPERARQEIEQYKDLCRALDQDNAMLQKDKEAVEQRLQHVKKERELLQKNLKQKPPKDEKVSLQVDISIAQDEKSRLTQEKQMLENKLEEMRKRILWEDPMMMLRTLPERKVVFKGLTTDKENMDKLVLTPLVRYPLSGGSALITFEKAEVAQRVIEMKEHVVELSHGEDPEDLDRCQVRVQAGPVDILLPSALEIGLTRGSRSILVSGLPSLGIPEDILLDKLELFFSKTKNGGSEVESREFLDDCGQVVLTFTQDGGVWDPLSTGLLEEESSPASSGKHWLSPKSRWSCEEWGWETELELSSVGDHARNITRSSTGGCGAQSFLLHLQWPSS", "length": 358, "header": "tr|A0A8V0ZQN5-1|A0A8V0ZQN5_CHICK Computationally mapped isoform of Interferon induced protein 35 OS=Gallus gallus OX=9031 GN=IFI35 PE=1 SV=1 CANONICAL=A0A8V0ZNC1-1" }, "locus": { "chromosome": "27", "start_pos": 5103227, "end_pos": 5100636, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054544.1", "url": "https://www.ensembl.org/id/ENSGALT00010054544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032950.1", "url": "https://www.ensembl.org/id/ENSGALP00010032950.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1" } ], "pmid": "" }, { "name": "regulation of innate immune response", "id": "GO:0045088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045088", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC1" }, { "id": "PF07292", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07292" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NID", "eco_id": "ECO_0000259", "start_pos": 166, "end_pos": 264, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNC8-1", "uniprot_ac": "A0A8V0ZNC8", "uniprot_id": "A0A8V0ZNC8_CHICK", "mass": { "chemical_mass": 48721.0, "monoisotopic_mass": 48721.0 }, "refseq": { "ac": "XP_418091", "name": "glial fibrillary acidic protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418091" }, "gene_names": [ { "name": "GFAP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8" } ] }, { "name": "GFAP", "type": "synonym", "evidence": [ { "id": "XP_418091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418091" } ] } ], "protein_names": [ { "name": "Glial fibrillary acidic protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8/entry#names_and_taxonomy" } ] }, { "name": "glial fibrillary acidic protein", "type": "synonym", "evidence": [ { "id": "XP_418091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418091" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_418091.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_418091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418091" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GFAP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8", "locus": { "chromosome": "27", "start_pos": 928160, "end_pos": 932697, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021974", "url": "https://www.ensembl.org/id/ENSGALG00010021974" } ] } } ], "crossref": [ { "id": "A0A8V0ZNC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "419969", "url": "https://www.ncbi.nlm.nih.gov/gene/419969", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419969", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419969", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QYETMAT", "url": "https://omabrowser.org/oma/group/QYETMAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNC8", "url": "https://www.orthodb.org/?gene=A0A8V0ZNC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45652:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45652:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04732", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04732", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_418091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_418091", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESRRLSYGRRFGPTGSAWSPTERPRPRGAHPAPRTSGRMDFSLANVLNSEFRETRTNEKVEMMELNDRFASYIEKVRLLEQRNKVLVLELNRAREQQPSRLGDVYQEELRELRRRVELLGTAKARAEVQRDGLAEELGSLREKLQQEVNLRLEAESTLAAYRQDVDAAALARLDLERRVGSLQDEVAFLQKVHEEELRELQEQLAQHQVHVEVDASKPDLTAALRDIRTQYEAMAASNMQETEEWYKSKFADLTDAAARHAEALRAAKHEANEYRRQLQALTCDLEALRGSNESLERQLRELEERYALETSAYQDTVGRLEEDIRSLKEEMGRHLQEYQDLLNVKLALDIEIATYRKLLEGEESRITVPVQSFSNLQIRETSLDTKSVSEAHVKRSIVVKTVETRDGEVIKESKQEHKEVV", "length": 422, "header": "tr|A0A8V0ZNC8-1|A0A8V0ZNC8_CHICK Isoform 1 of Glial fibrillary acidic protein OS=Gallus gallus OX=9031 GN=GFAP PE=3 SV=1 CANONICAL=A0A8V0ZNC8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8/entry#A0A8V0ZNC8-1", "sequence": { "sequence": "MESRRLSYGRRFGPTGSAWSPTERPRPRGAHPAPRTSGRMDFSLANVLNSEFRETRTNEKVEMMELNDRFASYIEKVRLLEQRNKVLVLELNRAREQQPSRLGDVYQEELRELRRRVELLGTAKARAEVQRDGLAEELGSLREKLQQEVNLRLEAESTLAAYRQDVDAAALARLDLERRVGSLQDEVAFLQKVHEEELRELQEQLAQHQVHVEVDASKPDLTAALRDIRTQYEAMAASNMQETEEWYKSKFADLTDAAARHAEALRAAKHEANEYRRQLQALTCDLEALRGSNESLERQLRELEERYALETSAYQDTVGRLEEDIRSLKEEMGRHLQEYQDLLNVKLALDIEIATYRKLLEGEESRITVPVQSFSNLQIRETSLDTKSVSEAHVKRSIVVKTVETRDGEVIKESKQEHKEVV", "length": 422, "header": "tr|A0A8V0ZNC8-1|A0A8V0ZNC8_CHICK Isoform 1 of Glial fibrillary acidic protein OS=Gallus gallus OX=9031 GN=GFAP PE=3 SV=1 CANONICAL=A0A8V0ZNC8-1" }, "locus": { "chromosome": "27", "start_pos": 932688, "end_pos": 929231, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053428.1", "url": "https://www.ensembl.org/id/ENSGALT00010053428.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032203.1", "url": "https://www.ensembl.org/id/ENSGALP00010032203.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419969", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419969", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7GGR8-1", "protein_name": "Glial fibrillary acidic protein", "gene_name": "Gfap", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MERRRITSARRSYASSETVVRGLGPSRHLGTIPRFSLARMPPPLPARVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDHLTANSARLEVERDNLAQDLGTLRQKLQDETNLRLEAENNLAAYRQEADEATMARLDLERKIESLEEEIQFLRKVHEEEVRELREQLAQQQVHVEMDVAKPDLTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDAASRNAELLRQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQDERHARESASYQEALARLEEEGQSLKEEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRGDKSTKEGEGHKVTRHLKRLTVQVIPIQAHQIVNAAPPTLETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM", "length": 470 }, "evidence": [ { "id": "A0A8V0ZNC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZNC8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P03995-1", "protein_name": "Glial fibrillary acidic protein", "gene_name": "Gfap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERRRITSARRSYASETVVRGLGPSRQLGTMPRFSLSRMTPPLPARVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNFAQDLGTLRQKLQDETNLRLEAENNLAAYRQEADEATLARVDLERKVESLEEEIQFLRKIYEEEVRELREQLAQQQVHVEMDVAKPDLTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDAASRNAELLRQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQEERHARESASYQEALARLEEEGQSLKEEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKDSKQEHKDVVM", "length": 430 }, "evidence": [ { "id": "A0A8V0ZNC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZNC8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P14136-1", "protein_name": "Glial fibrillary acidic protein", "gene_name": "GFAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM", "length": 432 }, "evidence": [ { "id": "A0A8V0ZNC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZNC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47819-1", "protein_name": "Glial fibrillary acidic protein", "gene_name": "Gfap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERRRITSARRSYASSETMVRGHGPTRHLGTIPRLSLSRMTPPLPARVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTTNSARLEVERDNLTQDLGTLRQKLQDETNLRLEAENNLAVYRQEADEATLARVDLERKVESLEEEIQFLRKIHEEEVRELQEQLAQQQVHVEMDVAKPDLTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDVASRNAELLRQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQEERHARESASYQEALARLEEEGQSLKEEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM", "length": 430 }, "evidence": [ { "id": "A0A8V0ZNC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZNC8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q28115-1", "protein_name": "Glial fibrillary acidic protein", "gene_name": "GFAP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MERRRVTSATRRSYVSSSEMVVGGRRLGPGTRLSLARMPPPLPARVDFSLAGALNSGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNLAQDLGTLRQKLQDETNQRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLAQQQVHVEMDVAKPDLTAALREIRTQYEAVASSNMHEAEEWYRSKFADLNDAAARNAELLRQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQEERHAREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM", "length": 428 }, "evidence": [ { "id": "A0A8V0ZNC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZNC8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "enteric nervous system development", "id": "GO:0048484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048484", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8" } ], "pmid": "" }, { "name": "regulation of chaperone-mediated autophagy", "id": "GO:1904714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904714", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of cytoskeleton", "id": "GO:0005200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNC8" } ], "pmid": "" }, { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", 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"ENSGALG00010022084", "url": "https://www.ensembl.org/id/ENSGALG00010022084" } ] } } ], "crossref": [ { "id": "A0A8V0ZNE9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNE9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR014912", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014912", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNE9", "url": "https://www.orthodb.org/?gene=A0A8V0ZNE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13077", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13077", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13077:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13077:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZNE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRAALAALLLLAAAAGIERRPPRGLARGKVEPGPPRTAPLCPQVKAFVSQDIPLYHNLEMKHLPGADPELVLLSFRYEELERIPLSDMTREEINQLVQELGFYRKETPEAPVPEEFQFAPAKPLPTLTPRRAPAADGKTLSEQDKDHPDL", "length": 151, "header": "tr|A0A8V0ZNE9-1|A0A8V0ZNE9_CHICK Isoform 1 of Selenoprotein M OS=Gallus gallus OX=9031 GN=SELENOM PE=1 SV=1 CANONICAL=A0A8V0ZNE9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE9/entry#A0A8V0ZNE9-1", "sequence": { "sequence": "MRRAALAALLLLAAAAGIERRPPRGLARGKVEPGPPRTAPLCPQVKAFVSQDIPLYHNLEMKHLPGADPELVLLSFRYEELERIPLSDMTREEINQLVQELGFYRKETPEAPVPEEFQFAPAKPLPTLTPRRAPAADGKTLSEQDKDHPDL", "length": 151, "header": "tr|A0A8V0ZNE9-1|A0A8V0ZNE9_CHICK Isoform 1 of Selenoprotein M OS=Gallus gallus OX=9031 GN=SELENOM PE=1 SV=1 CANONICAL=A0A8V0ZNE9-1" }, "locus": { "chromosome": "15", "start_pos": 9998282, "end_pos": 9997205, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053703.1", "url": "https://www.ensembl.org/id/ENSGALT00010053703.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032346.1", "url": "https://www.ensembl.org/id/ENSGALP00010032346.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE9" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNE9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNE9" }, { "id": "PF08806", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08806" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Selenoprotein F/M", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 103, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNF9-1", "uniprot_ac": "A0A8V0ZNF9", "uniprot_id": "A0A8V0ZNF9_CHICK", "mass": { "chemical_mass": 123700.0, "monoisotopic_mass": 123700.0 }, "refseq": { "ac": "XP_015132490", "name": "insulin receptor substrate 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132490" }, "gene_names": [ { "name": "LOC107051846", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ] }, { "name": "LOC107051846", "type": "synonym", "evidence": [ { "id": "XP_015132490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132490" } ] } ], "protein_names": [ { "name": "Insulin receptor substrate 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9/entry#names_and_taxonomy" } ] }, { "name": "insulin receptor substrate 1", "type": "synonym", "evidence": [ { "id": "XP_015132490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132490" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015132490.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015132490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015132490" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107051846", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9", "locus": {} } ], "crossref": [ { "id": "cd01204", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01204", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107051846", "url": "https://www.ncbi.nlm.nih.gov/gene/107051846", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107051846", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107051846", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MTMQMGC", "url": "https://omabrowser.org/oma/group/MTMQMGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNF9", "url": "https://www.orthodb.org/?gene=A0A8V0ZNF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10614:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10614:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-109704", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-109704", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-112399", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112399", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-112412", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112412", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-1266695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1266695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-198203", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198203", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-201556", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2428928", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2428928", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZNF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPTDNNEGFFSDVRKVGYLRKPKSMHKRFFVLRAASESGPARLEYYENEKKWRHKSGAPKRSIPLESCFNINKRADSKNKHLVALYTKDEHFAIAADSELEQESWYQALLQLHNRAKGHHHLHHHHHHHHSDVTFGGSSVGLGEAGEDSYGEVAPGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTNKTISFVKLNSDAAAVVLQLLNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSEEFRPRSKSQSSSNCSNPISVPLRSRHHINNPPPSQVGLSRRSRTESVTATSPAGGGGGGMGGKPSSFRVRASSDGEGTMSRPASVDGSPVSPSANRTHSHRHRGNSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGDEELNYICMGGKAASSCCSLAAPNGHFIPRTCHPQQQPRYPSTSCCPRAGSEDVADLDKAFRKRTHSAGTSPTISHQKTPSQSSVASIEEYTEMLPSYPCGGSRLPSYRHSAFVPTHSYPEECLEMHHLDGSHHRTNSAPHTDDGYMPMSPGVAPLPSGGAAPKGGDYMPMSPKSVSAPQQIINPGRGGRHPPATVDSNGYMMMSPSGSYSPDSGSAGYGKIWTNGAGHHPKLSVESNEGKLPCGGGDYINMSPASGSTTSTPPDCYFGAAGQPGVEEAAAALHKPIYSYFSLPRSFKHVHRRGGGPAGEEGSPQPRVALGSGRLLYAAEDSSSSTSSDSLGGPGGPEGPASHSQPPRKVDTAVQTKGRLARPTRLSLGGPKASTLPRAREQPPLLLPPEPKSPGEYVNIEFVPGDKPPFPSAAPGLPRPPGGEAAEEYMNMELGPPRARCPGAFAAAAARPGRGAAPPGRDYVSMQLGGSCSDCADSPSPSSPAPLLGYADVRAGRSAAEKPPPAAAASPELPRPPAELAAAPPRSSSLLGGPGAGSAFTRVSLSPGRNQSAKVIRADPQGGRRRHSSETFSSTPSAARGAAGGGGGGPGAPFPCGGAGGAEEVKRHSSASFENVWLRPAAGEPPSASRGPGAALENGLNYIDLDLVKDCSHRRHHLHPPAEGASGPGGKPPQPRSPRGSSHSSDDLSAYASISFQKREEP", "length": 1176, "header": "tr|A0A8V0ZNF9-1|A0A8V0ZNF9_CHICK Isoform 1 of Insulin receptor substrate 1 OS=Gallus gallus OX=9031 GN=LOC107051846 PE=4 SV=1 CANONICAL=A0A8V0ZNF9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9/entry#A0A8V0ZNF9-1", "sequence": { "sequence": 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"length": 1176, "header": "tr|A0A8V0ZNF9-1|A0A8V0ZNF9_CHICK Isoform 1 of Insulin receptor substrate 1 OS=Gallus gallus OX=9031 GN=LOC107051846 PE=4 SV=1 CANONICAL=A0A8V0ZNF9-1" }, "locus": { "chromosome": "9", "start_pos": 8623557, "end_pos": 8623025, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057507.1", "url": "https://www.ensembl.org/id/ENSGALT00010057507.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034941.1", "url": "https://www.ensembl.org/id/ENSGALP00010034941.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1049, "start_aa": "Thr", "end_pos": 1049, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1049", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:107051846", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107051846", "resource": "KEGG Pathway" }, { "id": "R-GGA-109704", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-109704", "resource": "Reactome", "description": "PI3K Cascade" }, { "id": "R-GGA-112399", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112399", "resource": "Reactome", "description": "IRS-mediated signalling" }, { "id": "R-GGA-112412", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112412", "resource": "Reactome", "description": "SOS-mediated signalling" }, { "id": "R-GGA-1257604", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "resource": "Reactome", "description": "PIP3 activates 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"description": "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" }, { "id": "R-GGA-74713", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-74713", "resource": "Reactome", "description": "IRS activation" }, { "id": "R-GGA-74749", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-74749", "resource": "Reactome", "description": "Signal attenuation" }, { "id": "R-GGA-9842663", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9842663", "resource": "Reactome", "description": "Signaling by LTK" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F4P8-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "irs1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"length": 1099 }, "evidence": [ { "id": "A0A8V0ZNF9", "url": "https://omabrowser.org/oma/group/A0A8V0ZNF9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LLF1-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGHHDGAAGPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLAAPNGHYILPRGGNGHRCLPGAGLGTSPALTGEEAGPASDLDNRFRKRTHSAGTSPTISHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRMPNYRHSAFVPTHSYPEEGLEMHPLERRGGHHRQDTSSLHTDDGYMPMSPGVAPVPGTRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGSCSPDIGGGPSSGGSSSGAAPSGSSYGKLWTNGVGGHHSHALPHPKLPVESSSGKLLSCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGELEESARHQHLRLSSSSGRLLYAAAAEDSSSSTSSDSLGGGYCGARPEPGLPHLHHQVLQPHLPRKVDTAAQTNNRLARPTRLSLGDPKASTLPRAREQPPQPALLHPPEPKSPGEYVNIEFGGDQPGYLSGPVASHSAPSVRCSSQLQPAPREEETGAEEYMNMDLGPGRRAIWQESAGVQPGRVGPAPPGAASVCRPTRAVPSSRGDYMTMQMGCPRQSYVDTSPVAPISYADMRTGIVVEEASLPGATAAAPSASSATSASSAAPQGAGELAARSSLLGGPQGPGGLSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRAGNTVPFGGGAAVGGGGGGSSSTEDVKRHSSASFENVWLRPGELGGAPKELAQMCGAAGGLENGLNYIDLDLVKDFKQRPQERPPQPQPPPPPPPHQPLGNSESSSTSRSSEDLSAYASISFQKQPEDLQ", "length": 1241 }, "evidence": [ { "id": "A0A8V0ZNF9", "url": "https://omabrowser.org/oma/group/A0A8V0ZNF9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1235 }, "evidence": [ { "id": "A0A8V0ZNF9", "url": "https://omabrowser.org/oma/group/A0A8V0ZNF9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "insulin receptor binding", "id": "GO:0005158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005158", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "insulin-like growth factor receptor binding", "id": "GO:0005159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005159", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "signaling receptor complex adaptor activity", "id": "GO:0030159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030159", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase binding", "id": "GO:0043548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043548", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "caveola", "id": "GO:0005901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "positive regulation of fatty acid beta-oxidation", "id": "GO:0032000", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032000", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "negative regulation of insulin secretion", "id": "GO:0046676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "positive regulation of glycogen biosynthetic process", "id": "GO:0045725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "positive regulation of D-glucose import", "id": "GO:0046326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046326", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "positive regulation of insulin receptor signaling pathway", "id": "GO:0046628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase/protein kinase B signal transduction", "id": "GO:0043491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "insulin-like growth factor receptor signaling pathway", "id": "GO:0048009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNF9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1024, "end_pos": 1026, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 715, "end_pos": 717, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" }, { "id": "PS51064", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51064" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IRS-type PTB", "eco_id": "ECO_0000259", "start_pos": 161, "end_pos": 265, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZNF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNF9" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 116, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1049 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1024, "end_pos": 1026 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 715, "end_pos": 717 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQT0-1", "uniprot_ac": "A0A8V0ZQT0", "uniprot_id": "A0A8V0ZQT0_CHICK", "mass": { "chemical_mass": 87175.0, "monoisotopic_mass": 87175.0 }, "refseq": {}, "gene_names": [ { "name": "ABLIM1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ] } ], "protein_names": [ { "name": "Actin binding LIM protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ABLIM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0", "locus": { "chromosome": "6", "start_pos": 28610015, "end_pos": 28780672, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022454", "url": "https://www.ensembl.org/id/ENSGALG00010022454" } ] } } ], "crossref": [ { "id": "A0A8V0ZQT0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQT0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09327", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09327", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09328", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09328", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09329", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09329", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09330", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09330", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423911", "url": "https://www.ncbi.nlm.nih.gov/gene/423911", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNG3", "url": "https://www.orthodb.org/?gene=A0A8V0ZNG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNG7", "url": "https://www.orthodb.org/?gene=A0A8V0ZNG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNH2", "url": "https://www.orthodb.org/?gene=A0A8V0ZNH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ87", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ93", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQT0", "url": "https://www.orthodb.org/?gene=A0A8V0ZQT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24213:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24213:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16182", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16182", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZNG3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNG7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ87", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKEKVAHPQEPHHPSEKPVIHCHKCGEPCKGEVLRVQSRHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCNGCGEFVEGEVVTALGKTYHPNCFACTVCKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKELSASSNCAGCGRDIKNGQALLALDKQWHLGCFKCKACGKVLTGEYISKDGAPYCEKDYQVLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEDKLRHSSSEFFYPKSLVLRRPRSAELLSPPCIMNSIKKLRQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSAYEDRQERQSLGESPRTLSPTPSAEGYQDIRDRMIHRSTSQGSINSPVYSRHSYTPTMSRSPQHFHRPELLSTGVQRLSYLRTSSLSSTHHDSRPNSPFRHHFIPHVKGNEPSSGRNSPVPYRPDSRPLTPTYAQAPKHFHVPDQGVNIYRKPPIYKQHDAAALAAQSKSSEDIIKSSKFPAAHAPAPNEIPKIETDHWPGPPSLAAIGADMRRRSSGREEDDEELQRRRQLQEEQLMKLNSGLGQLILKEEMEKERSALSASRYDSPAHASASKTSSLPGYGKNGLHRPVSTDFGQYNSYGDVSGGVRDFQSLPDGHVPGMRMDRGVSMPNMLEPKIFPYEILMVTNRGRNKILKDVDRTRLERHLAPEVFQEIFGMTIQEFDKLPLWRRNDMKKKAKLF", "length": 774, "header": "tr|A0A8V0ZQT0-1|A0A8V0ZQT0_CHICK Isoform 1 of Actin binding LIM protein 1 OS=Gallus gallus OX=9031 GN=ABLIM1 PE=1 SV=1 CANONICAL=A0A8V0ZQT0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0/entry#A0A8V0ZNG3-1", "sequence": { "sequence": "MVKEKVAHPQEPHHPSEKPVIHCHKCGEPCKGEVLRVQSRHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCNGCGEFVEGEVVTALGKTYHPNCFACTVCKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKELSASSNCAGCGRDIKNGQALLALDKQWHLGCFKCKACGKVLTGEYISKDGAPYCEKDYQVLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEDKLRHSSSEFFYPKSLVLRRPRSAELLSPPCIMNSIKKLRQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSAYEDRQERQSLGESPRTLSPTPSAEGYQDIRDRMIHRSTSQGSINSPVYSRHSYTPTMSRSPQHFHRPGNEPSSGRNSPVPYRPDSRPLTPTYAQAPKHFHVPDQGVNIYRKPPIYKQHDAAALAAQSKSSEDIIKSSKFPAAHAPAPNEIPKIETDHWPGPPSLAAIGADMRRRSSGREEDDEELQRRRQLQEEQLMKLNSGLGQLILKEEMEKERSALSASRYDSPAHASASKTSSLPGYGKNGLHRPVSTDFGQYNSYGDVSGGVRDFQSLPDGHVPGMRMDRGVSMPNMLEPKIFPYEILMVTNRGRNKILKDVDRTRLERHLAPEVFQEIFGMTIQEFDKLPLWRRNDMKKKAKLF", "length": 734, "header": "tr|A0A8V0ZNG3-1|A0A8V0ZQT0_CHICK Computationally mapped isoform of Actin binding LIM protein 1 OS=Gallus gallus OX=9031 GN=ABLIM1 PE=1 SV=1 CANONICAL=A0A8V0ZQT0-1" }, "locus": { "chromosome": "6", "start_pos": 28712255, "end_pos": 28612585, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054615.1", "url": "https://www.ensembl.org/id/ENSGALT00010054615.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032994.1", "url": "https://www.ensembl.org/id/ENSGALP00010032994.1" } ] } }, { "isoform_ac": "A0A8V0ZNG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0/entry#A0A8V0ZNG7-1", "sequence": { "sequence": "MVKEKVAHPQEPHHPSEKPVIHCHKCGEPCKGEVLRVQSRHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCNGCGEFVEGEVVTALGKTYHPNCFACTVCKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKELSASSNCAGCGRDIKNGQALLALDKQWHLGCFKCKACGKVLTGEYISKDGAPYCEKDYQVLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEDKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSAYEDRQERQSLGESPRTLSPTPSAEGYQDIRDRMIHRSTSQGSINSPVYSRHSYTPTMSRSPQHFHRPDQGVNIYRKPPIYKQHAALAAQSKSSEDIIKSSKFPAAHAPAPNEIPKIETDHWPGPPSLAAIGADMRRRSSGREEDDEELQRRRQLQEEQLMKLNSGLGQLILKEEMEKERSALSASRYDSPAHASASKTSSLPGYGKNGLHRPVSTDFGQYNSYGDVSGGVRDFQSLPDGHVPGMRMDRGVSMPNMLEPKIFPYEILMVTNRGRNKILKDVDRTRLERHLAPEVFQEIFGMTIQEFDKLPLWRRNDMKKKAKLF", "length": 660, "header": "tr|A0A8V0ZNG7-1|A0A8V0ZNG7_CHICK Computationally mapped isoform of Actin binding LIM protein 1 OS=Gallus gallus OX=9031 GN=ABLIM1 PE=1 SV=1 CANONICAL=A0A8V0ZQT0-1" }, "locus": { "chromosome": "6", "start_pos": 28712255, "end_pos": 28612585, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054626.1", "url": "https://www.ensembl.org/id/ENSGALT00010054626.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032999.1", "url": "https://www.ensembl.org/id/ENSGALP00010032999.1" } ] } }, { "isoform_ac": "A0A8V0ZNH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0/entry#A0A8V0ZNH2-1", "sequence": { "sequence": "MSARVAHPQEPHHPSEKPVIHCHKCGEPCKGEVLRVQSRHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCNGCGEFVEGEVVTALGKTYHPNCFACTVCKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKELSASSNCAGCGRDIKNGQALLALDKQWHLGCFKCKACGKVLTGEYISKDGAPYCEKDYQVLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEDKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSAYEDRQERQSLGESPRTLSPTPSAEGYQDIRDRMIHRSTSQGSINSPVYSRHSYTPTMSRSPQHFHRPGNEPSSGRNSPVPYRPDSRPLTPTYAQAPKHFHVPDQGVNIYRKPPIYKQHAALAAQSKSSEDIIKSSKFPAAHAPAPNEIPKIETDHWPGPPSLAAIGADMRRRSSGREEDDEELQRRRQLQEEQLMKLNSGLGQLILKEEMEKERSALSASRYDSPAHASASKTSSLPGYGKNGLHRPVSTDFGQYNSYGDVSGGVRDFQSLPDGHVPGMRMDRGVSMPNMLEPKIFPYEILMVTNRGRNKILKDVDRTRLERHLAPEVFQEIFGMTIQEFDKLPLWRRNDMKKKAKLF", "length": 694, "header": "tr|A0A8V0ZNH2-1|A0A8V0ZNH2_CHICK Computationally mapped isoform of Actin binding LIM protein 1 OS=Gallus gallus OX=9031 GN=ABLIM1 PE=1 SV=1 CANONICAL=A0A8V0ZQT0-1" }, "locus": { "chromosome": "6", "start_pos": 28780570, "end_pos": 28612585, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054636.1", "url": "https://www.ensembl.org/id/ENSGALT00010054636.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033004.1", "url": "https://www.ensembl.org/id/ENSGALP00010033004.1" } ] } }, { "isoform_ac": "A0A8V0ZQ87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0/entry#A0A8V0ZQ87-1", "sequence": { "sequence": 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"Ensembl Transcript", "id": "ENSGALT00010054617.1", "url": "https://www.ensembl.org/id/ENSGALT00010054617.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032996.1", "url": "https://www.ensembl.org/id/ENSGALP00010032996.1" } ] } }, { "isoform_ac": "A0A8V0ZQ93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0/entry#A0A8V0ZQ93-1", "sequence": { "sequence": "MELEIHQSSANGKVAHPQEPHHPSEKPVIHCHKCGEPCKGEVLRVQSRHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCNGCGEFVEGEVVTALGKTYHPNCFACTVCKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKELSASSNCAGCGRDIKNGQALLALDKQWHLGCFKCKACGKVLTGEYISKDGAPYCEKDYQVLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEDKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSAYEDRQERQSLGESPRTLSPTPSAEGYQDIRDRMIHRSTSQGSINSPVYSRHSYTPTMSRSPQHFHRPGNEPSSGRNSPVPYRPDSRPLTPTYAQAPKHFHVPDQGVNIYRKPPIYKQHDAAALAAQSKSSEDIIKSSKFPAAHAPAPNEIPKIETDHWPGPPSLAAIGADMRRRSSGREEDDEELQRRRQLQEEQLMKLNSGLGQLILKEEMEKERSALSASRYDSPAHASASKTSSLPGYGKNGLHRPVSTDFGQYNSYGDVSGGVRDFQSLPDGHVPGMRMDRGVSMPNMLEPKIFPYEILMVTNRGRNKILKDVDRTRLERHLAPEVFQEIFGMTIQEFDKLPLWRRNDMKKKAKLF", "length": 705, "header": "tr|A0A8V0ZQ93-1|A0A8V0ZQ93_CHICK Computationally mapped isoform of Actin binding LIM protein 1 OS=Gallus gallus OX=9031 GN=ABLIM1 PE=1 SV=1 CANONICAL=A0A8V0ZQT0-1" }, "locus": { "chromosome": "6", "start_pos": 28737559, "end_pos": 28612585, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054629.1", "url": "https://www.ensembl.org/id/ENSGALT00010054629.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033001.1", "url": "https://www.ensembl.org/id/ENSGALP00010033001.1" } ] } }, { "isoform_ac": "A0A8V0ZQT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0/entry#A0A8V0ZQT0-1", "sequence": { "sequence": "MVKEKVAHPQEPHHPSEKPVIHCHKCGEPCKGEVLRVQSRHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCNGCGEFVEGEVVTALGKTYHPNCFACTVCKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKELSASSNCAGCGRDIKNGQALLALDKQWHLGCFKCKACGKVLTGEYISKDGAPYCEKDYQVLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEDKLRHSSSEFFYPKSLVLRRPRSAELLSPPCIMNSIKKLRQPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSAYEDRQERQSLGESPRTLSPTPSAEGYQDIRDRMIHRSTSQGSINSPVYSRHSYTPTMSRSPQHFHRPELLSTGVQRLSYLRTSSLSSTHHDSRPNSPFRHHFIPHVKGNEPSSGRNSPVPYRPDSRPLTPTYAQAPKHFHVPDQGVNIYRKPPIYKQHDAAALAAQSKSSEDIIKSSKFPAAHAPAPNEIPKIETDHWPGPPSLAAIGADMRRRSSGREEDDEELQRRRQLQEEQLMKLNSGLGQLILKEEMEKERSALSASRYDSPAHASASKTSSLPGYGKNGLHRPVSTDFGQYNSYGDVSGGVRDFQSLPDGHVPGMRMDRGVSMPNMLEPKIFPYEILMVTNRGRNKILKDVDRTRLERHLAPEVFQEIFGMTIQEFDKLPLWRRNDMKKKAKLF", "length": 774, "header": "tr|A0A8V0ZQT0-1|A0A8V0ZQT0_CHICK Isoform 1 of Actin binding LIM protein 1 OS=Gallus gallus OX=9031 GN=ABLIM1 PE=1 SV=1 CANONICAL=A0A8V0ZQT0-1" }, "locus": { "chromosome": "6", "start_pos": 28712255, "end_pos": 28612585, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054601.1", "url": "https://www.ensembl.org/id/ENSGALT00010054601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032985.1", "url": "https://www.ensembl.org/id/ENSGALP00010032985.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 394, "start_aa": "Thr", "end_pos": 394, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr394", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "pmid": "" }, { "name": "lamellipodium assembly", "id": "GO:0030032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030032", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], 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"enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 394 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNI0-1", "uniprot_ac": "A0A8V0ZNI0", "uniprot_id": "A0A8V0ZNI0_CHICK", "mass": { "chemical_mass": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNI0", "url": "https://www.orthodb.org/?gene=A0A8V0ZNI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTT3", "url": "https://www.orthodb.org/?gene=A0A8V0ZTT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22427:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22427:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZNI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARCGSGAAPKGPGPGAAERQRLKEALAEQLRQDLSRLLADGTRSDVTIRVGDAALRAHRAVLLARAPRLFGGLGGGRPPRETLRLHGPGPAELRRFLRLVYSSDKNLQESEELAMMKKVLEPKLIQENNMERSEEQQTDVSCLGDDKSAADQNALSRAVQKEAACSPSREGDTSEFVAAESNKAMAGNSKLETASALGDDLLRLYKKRCCPDINICIEGKDFQAHRAILCARSSYFAAMLSGSWAENSQEHITLQGLSHIEMSVILHFIYGAILDFPAEVDVGRMLGIADMYGLDGLKEVAIYILKRDYCNFFQKPIPGKQQPILECMAIAHSLGVEHLYAACMKWVGKHFAKCLSERSFASLPTELQNNCLVMLIKSLNHKNAASLLMESDRLINSLPQVKWTERAVAVASRLQEECLTFIVANFLHVVQSEGFYVLLQAQAMSSKPDLLELIFNAIEKNINNENSCFLLVAVDTLLDSADVKELGFTCKIQALRDKLWVFLVQSFYAVRHTEGWKLMRPDHQQKIQAAAFDKGDDRRLAKKPVFTSSQLNKAITELSGKRNTSSWTEHGKKDCWGDSPTNRDKMKSDGLGASGHASSTNRNVANKTSKHEDVKAKDGKKTVSKLNKDLKPGEKAASPKARAVIKTKIENNGNAKAESMLAKQDAEKTTTSSGQKNSGSVKGLKNHEGKIAGARPKVLTVTSGVPVKTKPLKKTTGKESPSTATAAGTVTKLTNSSIDIQAASEQTEESKEEKIAEEGKKHTVITKPSLKTSNGVANKKKKADLEVNVTTSSLTKKTAGKASNEQNAQAVLKKKGNGSSNVAAQQKAQDTPTHSPKNQGTVGESPNSLKSGVSPKHNEERNVAQHLVQTTPPEKHPSAKKKSIKPSQTPVAKATAKTVTPKAQALLKHSEITNNKDPKPKTAGQSVLKSQSSTPKHSRSESPVVQKNTHTSEHRNLGQKLGKNAADVATVKPHDNNECSSAKQSECLKSVMGGSREDELLASCQPDKQKLLDPEDGEYKIQSKSPLVIGETVSKLHDSLQNEMEAREICGDQAEINQNKDRNVADNTAEFCCNAQSTSDGYADFSKETNQNAATSQELVEQSKVKKVCMEQSDQLSTDTGFNHGENILPRFSKGITNKEDVTSPPQIHMEGFCPADESCGTSALPEYKLVTVDLDDVSKRSIEQIRDKCSHNYIESVEPTEMPENHENAEIPFVDHWNTGALDPKESPESDTGSATTSSDDIKPRSEDYDAGGSQDDEGSNERGISKCSTMLCHDFLGRSSSDTSTPEELKIYDSSLRIEVKMKKEGSDLFRVNSTSDDEIPRKKSEIWSHQESARNSTRETENSTFGNAQFTQEADQVSSSADETEDDRSEPENVAGNILSSNVPPQQFQGIDNLAFEDATENATASQEFSKTKGFKRSVLLSVDECEELGSDDRVETHTSHQHSIDSLTPSDVFDSVSQEHHGKTFYSRYSLEIEDGLLDCKQPKDQDSRMDENESSLQHLHGTETPGKEDKGTLVAEANCAEEVHSAASPCPGENEKVNTKNEVATEFRQCNKYLDSDAKSQERPCHLNLHQRESNADVQKSNSTKPVEASKNQILTQEGQVRDSQPAPTEYDNTDLLPGDIDDYDTMAQTCMYEHRPSKTLSPIYEMDVGEAIEQRMDSETAVLDVDFEDQQFAEQDWTLLRQLLSEQDSNIGFKNSVPEDLNLAQCLINQTLFLARDGSNPQGTSQVDTFSRWTELMSPLDDSSASITVASFSSEDCSSPQGEWTILELETHH", "length": 1780, "header": "tr|A0A8V0ZNI0-1|A0A8V0ZNI0_CHICK Isoform 1 of BTB/POZ domain-containing protein 8 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZNI0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI0/entry#A0A8V0ZNI0-1", "sequence": { "sequence": "MARCGSGAAPKGPGPGAAERQRLKEALAEQLRQDLSRLLADGTRSDVTIRVGDAALRAHRAVLLARAPRLFGGLGGGRPPRETLRLHGPGPAELRRFLRLVYSSDKNLQESEELAMMKKVLEPKLIQENNMERSEEQQTDVSCLGDDKSAADQNALSRAVQKEAACSPSREGDTSEFVAAESNKAMAGNSKLETASALGDDLLRLYKKRCCPDINICIEGKDFQAHRAILCARSSYFAAMLSGSWAENSQEHITLQGLSHIEMSVILHFIYGAILDFPAEVDVGRMLGIADMYGLDGLKEVAIYILKRDYCNFFQKPIPGKQQPILECMAIAHSLGVEHLYAACMKWVGKHFAKCLSERSFASLPTELQNNCLVMLIKSLNHKNAASLLMESDRLINSLPQVKWTERAVAVASRLQEECLTFIVANFLHVVQSEGFYVLLQAQAMSSKPDLLELIFNAIEKNINNENSCFLLVAVDTLLDSADVKELGFTCKIQALRDKLWVFLVQSFYAVRHTEGWKLMRPDHQQKIQAAAFDKGDDRRLAKKPVFTSSQLNKAITELSGKRNTSSWTEHGKKDCWGDSPTNRDKMKSDGLGASGHASSTNRNVANKTSKHEDVKAKDGKKTVSKLNKDLKPGEKAASPKARAVIKTKIENNGNAKAESMLAKQDAEKTTTSSGQKNSGSVKGLKNHEGKIAGARPKVLTVTSGVPVKTKPLKKTTGKESPSTATAAGTVTKLTNSSIDIQAASEQTEESKEEKIAEEGKKHTVITKPSLKTSNGVANKKKKADLEVNVTTSSLTKKTAGKASNEQNAQAVLKKKGNGSSNVAAQQKAQDTPTHSPKNQGTVGESPNSLKSGVSPKHNEERNVAQHLVQTTPPEKHPSAKKKSIKPSQTPVAKATAKTVTPKAQALLKHSEITNNKDPKPKTAGQSVLKSQSSTPKHSRSESPVVQKNTHTSEHRNLGQKLGKNAADVATVKPHDNNECSSAKQSECLKSVMGGSREDELLASCQPDKQKLLDPEDGEYKIQSKSPLVIGETVSKLHDSLQNEMEAREICGDQAEINQNKDRNVADNTAEFCCNAQSTSDGYADFSKETNQNAATSQELVEQSKVKKVCMEQSDQLSTDTGFNHGENILPRFSKGITNKEDVTSPPQIHMEGFCPADESCGTSALPEYKLVTVDLDDVSKRSIEQIRDKCSHNYIESVEPTEMPENHENAEIPFVDHWNTGALDPKESPESDTGSATTSSDDIKPRSEDYDAGGSQDDEGSNERGISKCSTMLCHDFLGRSSSDTSTPEELKIYDSSLRIEVKMKKEGSDLFRVNSTSDDEIPRKKSEIWSHQESARNSTRETENSTFGNAQFTQEADQVSSSADETEDDRSEPENVAGNILSSNVPPQQFQGIDNLAFEDATENATASQEFSKTKGFKRSVLLSVDECEELGSDDRVETHTSHQHSIDSLTPSDVFDSVSQEHHGKTFYSRYSLEIEDGLLDCKQPKDQDSRMDENESSLQHLHGTETPGKEDKGTLVAEANCAEEVHSAASPCPGENEKVNTKNEVATEFRQCNKYLDSDAKSQERPCHLNLHQRESNADVQKSNSTKPVEASKNQILTQEGQVRDSQPAPTEYDNTDLLPGDIDDYDTMAQTCMYEHRPSKTLSPIYEMDVGEAIEQRMDSETAVLDVDFEDQQFAEQDWTLLRQLLSEQDSNIGFKNSVPEDLNLAQCLINQTLFLARDGSNPQGTSQVDTFSRWTELMSPLDDSSASITVASFSSEDCSSPQGEWTILELETHH", "length": 1780, "header": "tr|A0A8V0ZNI0-1|A0A8V0ZNI0_CHICK Isoform 1 of BTB/POZ domain-containing protein 8 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZNI0-1" }, "locus": { "chromosome": "8", "start_pos": 14007046, "end_pos": 13972737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053521.1", "url": "https://www.ensembl.org/id/ENSGALT00010053521.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032248.1", "url": "https://www.ensembl.org/id/ENSGALP00010032248.1" } ] } }, { "isoform_ac": "A0A8V0ZTT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI0/entry#A0A8V0ZTT3-1", "sequence": { "sequence": "MVLSVLLWLVYSSDKNLQESEELAMMKKVLEPKLIQENNMERSEEQQTDVSCLGDDKSAADQNALSRAVQKEAACSPSREGDTSEFVAAESNKAMAGNSKLETASALGDDLLRLYKKRCCPDINICIEGKDFQAHRAILCARSSYFAAMLSGSWAENSQEHITLQGLSHIEMSVILHFIYGAILDFPAEVDVGRMLGIADMYGLDGLKEVAIYILKRDYCNFFQKPIPGKQQPILECMAIAHSLGVEHLYAACMKWVGKHFAKCLSERSFASLPTELQNNCLVMLIKSLNHKNAASLLMESDRLINSLPQVKWTERAVAVASRLQEECLTFIVANFLHVVQSEGFYVLLQAQAMSSKPDLLELIFNAIEKNINNENSCFLLVAVDTLLDSADVKELGFTCKIQALRDKLWVFLVQSFYAVRHTEGWKLMRPDHQQKIQAAAFDKGDDRRLAKKPVFTSSQLNKAITELSGKRNTSSWTEHGKKDCWGDSPTNRDKMKSDGLGASGHASSTNRNVANKTSKHEDVKAKDGKKTVSKLNKDLKPGEKAASPKARAVIKTKIENNGNAKAESMLAKQDAEKTTTSSGQKNSGSVKGLKNHEGKIAGARPKVLTVTSGVPVKTKPLKKTTGKESPSTATAAGTVTKLTNSSIDIQAASEQTEESKEEKIAEEGKKHTVITKPSLKTSNGVANKKKKADLEVNVTTSSLTKKTAGKASNEQNAQAVLKKKGNGSSNVAAQQKAQDTPTHSPKNQGTVGESPNSLKSGVSPKHNEERNVAQHLVQTTPPEKHPSAKKKSIKPSQTPVAKATAKTVTPKAQALLKHSEITNNKDPKPKTAGQSVLKSQSSTPKHSRSESPVVQKNTHTSEHRNLGQKLGKNAADVATVKPHDNNECSSAKQSECLKSVMGGSREDELLASCQPDKQKLLDPEDGEYKIQSKSPLVIGETVSKLHDSLQNEMEAREICGDQAEINQNKDRNVADNTAEFCCNAQSTSDGYADFSKETNQNAATSQELVEQSKVKKVCMEQSDQLSTDTGFNHGENILPRFSKGITNKEDVTSPPQIHMEGFCPADESCGTSALPEYKLVTVDLDDVSKRSIEQIRDKCSHNYIESVEPTEMPENHENAEIPFVDHWNTGALDPKESPESDTGSATTSSDDIKPRSEDYDAGGSQDDEGSNERGISKCSTMLCHDFLGRSSSDTSTPEELKIYDSSLRIEVKMKKEGSDLFRVNSTSDDEIPRKKSEIWSHQESARNSTRETENSTFGNAQFTQEADQVSSSADETEDDRSEPENVAGNILSSNVPPQQFQGIDNLAFEDATENATASQEFSKTKGFKRSVLLSVDECEELGSDDRVETHTSHQHSIDSLTPSDVFDSVSQEHHGKTFYSRYSLEIEDGLLDCKQPKDQDSRMDENESSLQHLHGTETPGKEDKGTLVAEANCAEEVHSAASPCPGENEKVNTKNEVATEFRQCNKYLDSDAKSQERPCHLNLHQRESNADVQKSNSTKPVEASKNQILTQEGQVRDSQPAPTEYDNTDLLPGDIDDYDTMAQTCMYEHRPSKTLSPIYEMDVGEAIEQRMDSETAVLDVDFEDQQFAEQDWTLLRQLLSEQDSNIGFKNSVPEDLNLAQCLINQTLFLARDGSNPQGTSQVDTFSRWTELMSPLDDSSASITVASFSSEDCSSPQGEWTILELETHH", "length": 1689, "header": "tr|A0A8V0ZTT3-1|A0A8V0ZNI0_CHICK Computationally mapped isoform of BTB/POZ domain-containing protein 8 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZNI0-1" }, "locus": { "chromosome": "8", "start_pos": 14006422, "end_pos": 13972737, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053518.1", "url": "https://www.ensembl.org/id/ENSGALT00010053518.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032246.1", "url": "https://www.ensembl.org/id/ENSGALP00010032246.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "extrinsic component of synaptic vesicle membrane", "id": "GO:0098850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098850", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI0" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI0" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "synaptic vesicle budding from endosome", "id": "GO:0016182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI0" } ], "pmid": "" }, { "name": "synaptic vesicle endocytosis", "id": "GO:0048488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048488", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1316, "end_pos": 1318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1339, "end_pos": 1341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1346, "end_pos": 1348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1406, "end_pos": 1408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1498, "end_pos": 1500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1588, "end_pos": 1590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1716, "end_pos": 1718, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 736, "end_pos": 738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 818, "end_pos": 820, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI0" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 110, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1316, "end_pos": 1318 }, { "start_pos": 1339, "end_pos": 1341 }, { "start_pos": 1346, "end_pos": 1348 }, { "start_pos": 1406, "end_pos": 1408 }, { "start_pos": 1498, "end_pos": 1500 }, { "start_pos": 1588, "end_pos": 1590 }, { "start_pos": 1716, "end_pos": 1718 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 607, "end_pos": 609 }, { "start_pos": 736, "end_pos": 738 }, { "start_pos": 789, "end_pos": 791 }, { "start_pos": 818, "end_pos": 820 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNI1-1", "uniprot_ac": "A0A8V0ZNI1", "uniprot_id": "A0A8V0ZNI1_CHICK", "mass": { "chemical_mass": 437343.0, "monoisotopic_mass": 437343.0 }, "refseq": {}, "gene_names": [ { "name": "TRRAP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI1" } ] } ], "protein_names": [ { "name": "Transformation/transcription domain associated protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TRRAP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI1", "locus": { "chromosome": "14", "start_pos": 1405036, "end_pos": 1327249, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022090", "url": "https://www.ensembl.org/id/ENSGALG00010022090" } ] } } ], "crossref": [ { "id": "cd05163", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05163", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416440", "url": "https://www.ncbi.nlm.nih.gov/gene/416440", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046805", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046805", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11139:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11139:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02259", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02259", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20175", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20175", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20206", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20206", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-201722", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZNI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU41", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFVSAQGPTVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYSTFLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRLHTKNILSVMFRFLETENEENVLICLRIIIELHKQFRPAITQEIHHFLDFVKQIYKELPKVVGRYFENPQVIPENTVPPPEMVGMITTIVVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYKLNIHNVVAEFVPLIMNTIIIQVSAQARQHKLYNKELYADFIAAQIKTLSFLAYIIRIYQELVAKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTDLRSQFIPCMDKLFDESILIGSGYTARETLRPLAYSTLADLVHHVRQHLPLNDLSLAVQLFAKNIDDESLPSSIQTMSCKLLLNLVDCIRSKSEQENGNGRDILMRMLEVFVLKFHTIARYQLSGIFKKCKPQSELGAAEAALPGVPTAANAAPVPVPSPAPATPVAPAPVPVFEKQGEKEKEDKQTFQVTDCRSLVKTLVCGVKTITWGITSCKAPGEAQFIPNKQLQPKETQIYIKLVKYAMQALDIYQVQIAGNGQTYVRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVERISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMGSNVELSNLYLKLFKLVFGSVSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQTLVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNPADSISHVAYRVLGKFGGSNRKMLKESQKLQYVVTEIQGPSITIEFSDCKASIQLPMEKAIETALDCLKSANTEPYYRRQAWEVIKCFLVAMMSLDDNKHALYQLLAHPNFTEKSIPSVIISHRYKAQDTPARKTFEQALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLQCYQVGSQPSTAMFHSEENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSYIVERLCACCYEQAWYAKLGGVVSIKFLMERLPLIWVLQNQQTFLKALLFVMMDLTGEVSNGAVAMAKTTLEQLLIRCATPLKDEEKTEEIIAAQEKSFHHVTHDLVREVTSPNSTVRKQAMHSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNVVEHKVFYTELLNLCEAEDTALMKLPCYKSLPSLVPLRIAALNALAACNYLPQSREKIIAALFKALNSTNNELQEAGEACMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNEMKICSAIINLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEATLNDPQWSRMFMSFLKHKDAKPLRDVLAANPNRFITLLLPAGTQATVRPGSPSTTTMRLDLQFQAIKIISIIVKNDECWLANQHSLVSQLKRVWVSEAFQERHRKENMAATNWKEPKLLAYCLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIPQKRALFFRFVDFNDPNFGDELKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPEGDNPESITSVFITKVLDPEKQADMLDSLRIYLLQFATLLVEHAPHHIHDNNKNRNSKLRRLMTFAWPCLLSKACVDPACKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDGHQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSVTIEQRKLAVDLAEVVIKWELQRIKDQQPDSDVDPSASGEGASSTSSAVKRGLSVDSGQEVKRFRTATGAISAVFGRSQSLPGADALLSKPIDKQHTDTVVNFLIRIACQVNDNSNTAGSPGELLSRRCVNLLKTALRPDMWPKSELKLQWFDKLLMTVEQPNQANFANICTGLEVLSFLLTVLQPPAILSSFKPLQRGVAACMTCGNTKVLRAVHSLLSRLMGIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATNANPSQLFGTLMILKSACSNNPSYIDRLISVFMRSLQKMVREHLNPQATAGAAETNTAGTSELVMLSLDLVKTRLAVMSMEMRKNFIQAILTSLIEKSTDAKILRAVVKIVEEWVKNNSPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFLDLVNYVYRDENLSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVTCSQNWEAMGNHFWIKQCIELLLAVCERNTTIGTSCQGAMLPSITNVINLADSHDRAAFAMVTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKFLDSLREVKTGALLSAFVQLCHISTPLAEKTWIQLFSRLWKILSDRQQHALAGEISPFLCSGSHQVQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTHNLWFRSTLMLEHQAFEKGLSLQIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKFPETATAIAYEQHGFFEQAQETYEKAMEKAKKEHERNNASPSIFPEYQLWEDHWIRCSKELNQWEPLTEYGQSKGHINPYLVLECAWRVSNWTAMKEALVQVELSCPKEMAWKVNMYRGYLAICHPEEQQLNFIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNLGRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQAIVTAYENSSQHDPSSNNAMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLENIFVKERQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSDSGQQQPSSVGNQSHSASDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSNVSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFLMPKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFIFHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQEDTSSPLSAAGQPENMDSQQLVSLVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAANSLDNLCRMDPAWHPWLLNTALWQKLKRPNSKCDL", "length": 3855, "header": "tr|A0A8V0ZNI1-1|A0A8V0ZNI1_CHICK Isoform 1 of Transformation/transcription domain associated protein OS=Gallus gallus OX=9031 GN=TRRAP PE=1 SV=1 CANONICAL=A0A8V0ZNI1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI1/entry#A0A8V0ZNI1-1", "sequence": { "sequence": "MAFVSAQGPTVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYSTFLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRLHTKNILSVMFRFLETENEENVLICLRIIIELHKQFRPAITQEIHHFLDFVKQIYKELPKVVGRYFENPQVIPENTVPPPEMVGMITTIVVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYKLNIHNVVAEFVPLIMNTIIIQVSAQARQHKLYNKELYADFIAAQIKTLSFLAYIIRIYQELVAKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTDLRSQFIPCMDKLFDESILIGSGYTARETLRPLAYSTLADLVHHVRQHLPLNDLSLAVQLFAKNIDDESLPSSIQTMSCKLLLNLVDCIRSKSEQENGNGRDILMRMLEVFVLKFHTIARYQLSGIFKKCKPQSELGAAEAALPGVPTAANAAPVPVPSPAPATPVAPAPVPVFEKQGEKEKEDKQTFQVTDCRSLVKTLVCGVKTITWGITSCKAPGEAQFIPNKQLQPKETQIYIKLVKYAMQALDIYQVQIAGNGQTYVRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVERISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMGSNVELSNLYLKLFKLVFGSVSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQTLVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNPADSISHVAYRVLGKFGGSNRKMLKESQKLQYVVTEIQGPSITIEFSDCKASIQLPMEKAIETALDCLKSANTEPYYRRQAWEVIKCFLVAMMSLDDNKHALYQLLAHPNFTEKSIPSVIISHRYKAQDTPARKTFEQALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLQCYQVGSQPSTAMFHSEENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSYIVERLCACCYEQAWYAKLGGVVSIKFLMERLPLIWVLQNQQTFLKALLFVMMDLTGEVSNGAVAMAKTTLEQLLIRCATPLKDEEKTEEIIAAQEKSFHHVTHDLVREVTSPNSTVRKQAMHSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNVVEHKVFYTELLNLCEAEDTALMKLPCYKSLPSLVPLRIAALNALAACNYLPQSREKIIAALFKALNSTNNELQEAGEACMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNEMKICSAIINLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEATLNDPQWSRMFMSFLKHKDAKPLRDVLAANPNRFITLLLPAGTQATVRPGSPSTTTMRLDLQFQAIKIISIIVKNDECWLANQHSLVSQLKRVWVSEAFQERHRKENMAATNWKEPKLLAYCLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIPQKRALFFRFVDFNDPNFGDELKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPEGDNPESITSVFITKVLDPEKQADMLDSLRIYLLQFATLLVEHAPHHIHDNNKNRNSKLRRLMTFAWPCLLSKACVDPACKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDGHQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSVTIEQRKLAVDLAEVVIKWELQRIKDQQPDSDVDPSASGEGASSTSSAVKRGLSVDSGQEVKRFRTATGAISAVFGRSQSLPGADALLSKPIDKQHTDTVVNFLIRIACQVNDNSNTAGSPGELLSRRCVNLLKTALRPDMWPKSELKLQWFDKLLMTVEQPNQANFANICTGLEVLSFLLTVLQPPAILSSFKPLQRGVAACMTCGNTKVLRAVHSLLSRLMGIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATNANPSQLFGTLMILKSACSNNPSYIDRLISVFMRSLQKMVREHLNPQATAGAAETNTAGTSELVMLSLDLVKTRLAVMSMEMRKNFIQAILTSLIEKSTDAKILRAVVKIVEEWVKNNSPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFLDLVNYVYRDENLSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVTCSQNWEAMGNHFWIKQCIELLLAVCERNTTIGTSCQGAMLPSITNVINLADSHDRAAFAMVTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKFLDSLREVKTGALLSAFVQLCHISTPLAEKTWIQLFSRLWKILSDRQQHALAGEISPFLCSGSHQVQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTHNLWFRSTLMLEHQAFEKGLSLQIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKFPETATAIAYEQHGFFEQAQETYEKAMEKAKKEHERNNASPSIFPEYQLWEDHWIRCSKELNQWEPLTEYGQSKGHINPYLVLECAWRVSNWTAMKEALVQVELSCPKEMAWKVNMYRGYLAICHPEEQQLNFIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNLGRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQAIVTAYENSSQHDPSSNNAMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLENIFVKERQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSDSGQQQPSSVGNQSHSASDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSNVSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFLMPKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFIFHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQEDTSSPLSAAGQPENMDSQQLVSLVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAANSLDNLCRMDPAWHPWLLNTALWQKLKRPNSKCDL", "length": 3855, "header": "tr|A0A8V0ZNI1-1|A0A8V0ZNI1_CHICK Isoform 1 of Transformation/transcription domain associated protein OS=Gallus gallus OX=9031 GN=TRRAP PE=1 SV=1 CANONICAL=A0A8V0ZNI1-1" }, "locus": { "chromosome": "14", "start_pos": 1404468, "end_pos": 1330885, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053773.1", "url": "https://www.ensembl.org/id/ENSGALT00010053773.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032376.1", "url": "https://www.ensembl.org/id/ENSGALP00010032376.1" } ] } }, { "isoform_ac": "A0A8V0ZNU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI1/entry#A0A8V0ZNU2-1", "sequence": { "sequence": "MAFVSAQGPTVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYSTFLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRLHTKNILSVMFRFLETENEENVLICLRIIIELHKQFRPAITQEIHHFLDFVKQIYKELPKVVGRYFENPQVIPENTVPPPEMVGMITTIVVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYKLNIHNVVAEFVPLIMNTIIIQVSAQARQHKLYNKELYADFIAAQIKTLSFLAYIIRIYQELVAKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTDLRSQFIPCMDKLFDESILIGSGYTARETLRPLAYSTLADLVHHVRQHLPLNDLSLAVQLFAKNIDDESLPSSIQTMSCKLLLNLVDCIRSKSEQENGNGRDILMRMLEVFVLKFHTIARYQLSGIFKKCKPQSELGAAEAALPGVPTAANAAPVPVPSPAPATPVAPAPVPVFEKQGEKEKEDKQTFQVTDCRSLVKTLVCGVKTITWGITSCKAPGEAQFIPNKQLQPKETQIYIKLVKYAMQALDIYQVQIAGNGQTYVRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVERISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMGSNVELSNLYLKLFKLVFGSVSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQTLVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNPADSISHVAYRVLGKFGGSNRKMLKESQKLQYVVTEIQGPSITIEFSDCKASIQLPMEKAIETALDCLKSANTEPYYRRQAWEVIKCFLVAMMSLDDNKHALYQLLAHPNFTEKSIPSVIISHRYKAQDTPARKTFEQALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLQCYQVGSQPSTAMFHSEENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSYIVERLCACCYEQAWYAKLGGVVSIKFLMERLPLIWVLQNQQTFLKALLFVMMDLTGEVSNGAVAMAKTTLEQLLIRCATPLKDEEKTEEIIAAQEKSFHHVTHDLVREVTSPNSTVRKQAMHSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNVVEHKVFYTELLNLCEAEDTALMKLPCYKSLPSLVPLRIAALNALAACNYLPQSREKIIAALFKALNSTNNELQEAGEACMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNEMKICSAIINLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEATLNDPQWSRMFMSFLKHKDAKPLRDVLAANPNRFITLLLPAGTQATVRPGSPSTTTMRLDLQFQAIKIISIIVKNDECWLANQHSLVSQLKRVWVSEAFQERHRKENMAATNWKEPKLLAYCLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIPQKRALFFRFVDFNDPNFGDELKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPEGDNPESITSVFITKVLDPEKQADMLDSLRIYLLQFATLLVEHAPHHIHDNNKNRNSKLRRLMTFAWPCLLSKACVDPACKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDGHQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSVTIEQRKLAVDLAEVVIKWELQRIKDQQPDSDVDPSASGEGASSTSSAVKRGLSVDSGQEVKRFRTATGAISAVFGRSQSLPGADALLSKPIDKQHTDTVVNFLIRIACQVNDNSNTAGSPGELLSRRCVNLLKTALRPDMWPKSELKLQWFDKLLMTVEQPNQANFANICTGLEVLSFLLTVLQPPAILSSFKPLQRGVAACMTCGNTKVLRAVHSLLSRLMGIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATNANPSQLFGTLMILKSACSNNPSYIDRLISVFMRSLQKMVREHLNPQATAGAAETNTAGTSELVMLSLDLVKTRLAVMSMEMRKNFIQAILTSLIEKSTDAKILRAVVKIVEEWVKNNSPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFLDLVNYVYRDENLSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVTCSQNWEAMGNHFWIKQCIELLLAVCERNTTIGTSCQGAMLPSITNVINLADSHDRAAFAMVTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKFLDSLREVKTGALLSAFVQLCHISTPLAEKTWIQLFSRLWKILSDRQQHALAGEISPFLCSGSHQVQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTHNLWFRSTLMLEHQAFEKGLSLQIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKFPETATAIAYEQHGFFEQAQETYEKAMEKAKKEHERNNASPSIFPEYQLWEDHWIRCSKELNQWEPLTEYGQSKGHINPYLVLECAWRVSNWTAMKEALVQVELSCPKEMAWKVNMYRGYLAICHPEEQQLNFIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNLGRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQGKTAWSSMPSSSIVTAYENSSQHDPSSNNAMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLENIFVKERQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSDSGQQQPSSVGNQSHSASDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSNVSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFLMPKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFIFHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQEDTSSPLSAAGQPENMDSQQLVSLVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAANSLDNLCRMDPAWHPWL", "length": 3848, "header": "tr|A0A8V0ZNU2-1|A0A8V0ZNU2_CHICK Computationally mapped isoform of Transformation/transcription domain associated protein OS=Gallus gallus OX=9031 GN=TRRAP PE=1 SV=1 CANONICAL=A0A8V0ZNI1-1" }, "locus": { "chromosome": "14", "start_pos": 1403420, "end_pos": 1330885, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053738.1", "url": "https://www.ensembl.org/id/ENSGALT00010053738.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032360.1", "url": "https://www.ensembl.org/id/ENSGALP00010032360.1" } ] } }, { "isoform_ac": "A0A8V0ZU41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI1/entry#A0A8V0ZU41-1", "sequence": { "sequence": "MAFVSAQGPTVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYSTFLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRLHTKNILSVMFRFLETENEENVLICLRIIIELHKQFRPAITQEIHHFLDFVKQIYKELPKVVGRYFENPQVIPENTVPPPEMVGMITTIVVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYKLNIHNVVAEFVPLIMNTIIIQVSAQARQHKLYNKELYADFIAAQIKTLSFLAYIIRIYQELVAKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTDLRSQFIPCMDKLFDESILIGSGYTARETLRPLAYSTLADLVHHVRQHLPLNDLSLAVQLFAKNIDDESLPSSIQTMSCKLLLNLVDCIRSKSEQENGNGRDILMRMLEVFVLKFHTIARYQLSGIFKKCKPQSELGAAEAALPGVPTAANAAPVPVPSPAPATPVAPAPVPVFEKQGEKEKEDKQTFQVTDCRSLVKTLVCGVKTITWGITSCKAPGEAQFIPNKQLQPKETQIYIKLVKYAMQALDIYQVQIAGNGQTYVRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVERISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMGSNVELSNLYLKLFKLVFGSVSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFLPLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQTLVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNPADSISHVAYRVLGKFGGSNRKMLKESQKLQYVVTEIQGPSITIEFSDCKASIQLPMEKAIETALDCLKSANTEPYYRRQAWEVIKCFLVAMMSLDDNKHALYQLLAHPNFTEKSIPSVIISHRYKAQDTPARKTFEQALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLQCYQVGSQPSTAMFHSEENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSYIVERLCACCYEQAWYAKLGGVVSIKFLMERLPLIWVLQNQQTFLKALLFVMMDLTGEVSNGAVAMAKTTLEQLLIRCATPLKDEEKTEEIIAAQEKSFHHVTHDLVREVTSPNSTVRKQAMHSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQPRLFTMDLNVVEHKVFYTELLNLCEAEDTALMKLPCYKSLPSLVPLRIAALNALAACNYLPQSREKIIAALFKALNSTNNELQEAGEACMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSLTLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNEMKICSAIINLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEATLNDPQWSRMFMSFLKHKDAKPLRDVLAANPNRFITLLLPAGTQATVRPGSPSTTTMRLDLQFQAIKIISIIVKNDECWLANQHSLVSQLKRVWVSEAFQERHRKENMAATNWKEPKLLAYCLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIPQKRALFFRFVDFNDPNFGDELKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPEGDNPESITSVFITKVLDPEKQADMLDSLRIYLLQFATLLVEHAPHHIHDNNKNRNSKLRRLMTFAWPCLLSKACVDPACKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDGHQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSVTIEQRKLAVDLAEVVIKWELQRIKDQQPDSDVDPSASGEGASSTSSAVKRGLSVDSGQEVKRFRTATGAISAVFGRSQSLPGADALLSKPIDKQHTDTVVNFLIRIACQVNDNSNTAGSPGELLSRRCVNLLKTALRPDMWPKSELKLQWFDKLLMTVEQPNQANFANICTGLEVLSFLLTVLQPPAILSSFKPLQRGVAACMTCGNTKVLRAVHSLLSRLMGIFPTEPSTSSVASKYEELECLYAAVGKVIYEGLTNYEKATNANPSQLFGTLMILKSACSNNPSYIDRLISVFMRSLQKMVREHLNPQATAGAAETNTAGTSELVMLSLDLVKTRLAVMSMEMRKNFIQAILTSLIEKSTDAKILRAVVKIVEEWVKNNSPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFLDLVNYVYRDENLSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVTCSQNWEAMGNHFWIKQCIELLLAVCERNTTIGTSCQGAMLPSITNVINLADSHDRAAFAMVTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKFLDSLREVKTGALLSAFVQLCHISTPLAEKTWIQLFSRLWKILSDRQQHALAGEISPFLCSGSHQVQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTHNLWFRSTLMLEHQAFEKGLSLQIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKFPETATAIAYEQHGFFEQAQETYEKAMEKAKKEHERNNASPSIFPEYQLWEDHWIRCSKELNQWEPLTEYGQSKGHINPYLVLECAWRVSNWTAMKEALVQVELSCPKEMAWKVNMYRGYLAICHPEEQQLNFIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNLGRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQAIVTAYENSSQHDPSSNNAMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQLAGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMHDVLVKAWAMWGDYLENIFVKERQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFDDDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYKSDSGQQQPSSVGNQSHSASDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSNVSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFLMPKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQASHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFIFHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQEDTSSPLSAAGQPENMDSQQLVSLVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAANSLDNLCRMDPAWHPWL", "length": 3837, "header": "tr|A0A8V0ZU41-1|A0A8V0ZNI1_CHICK Computationally mapped isoform of Transformation/transcription domain associated protein OS=Gallus gallus OX=9031 GN=TRRAP PE=1 SV=1 CANONICAL=A0A8V0ZNI1-1" }, "locus": { "chromosome": "14", "start_pos": 1403420, "end_pos": 1330885, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053756.1", "url": "https://www.ensembl.org/id/ENSGALT00010053756.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032368.1", "url": "https://www.ensembl.org/id/ENSGALP00010032368.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 505, "start_aa": "Thr", "end_pos": 505, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr505", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-201722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201722", "resource": "Reactome", "description": "Formation of the beta-catenin:TCF transactivating complex" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI1" } ], "pmid": "" }, { "name": "nucleoplasm", 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Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015145181.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015145181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145181" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KLHL23", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI2", "locus": { "chromosome": "7", "start_pos": 18206896, "end_pos": 18212567, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023639", "url": "https://www.ensembl.org/id/ENSGALG00010023639" } ] } } ], "crossref": [ { "id": "A0A8V0ZNI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18252", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18252", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18462", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18462", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429025", "url": "https://www.ncbi.nlm.nih.gov/gene/429025", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429025", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429025", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIWDPIS", "url": "https://omabrowser.org/oma/group/HIWDPIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNI2", "url": "https://www.orthodb.org/?gene=A0A8V0ZNI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015145181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015145181", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPGQEDYEFAYRDSSHPVCLLDAFRAFYLDGLFTDIALQAASGVLLHCHRAVLAACSSYFRAMFTADMKEKSKNQIRLPELSHAVLEALVNYAYTSQIQITKRNVQSLLQAADLLQFVSVKRACEQFLIRHLDADNCLGMHAFAEHHNCLELEKESRRMLLWQFEEVWKQEEFLDVSKEKLAFILSRENLNVWKEEAAVGAVVRWVAHNVEERIEDIYELLSCIKLDLDNVYLRSALSLQKKCRLNDNKIRSLVYSALNPSPKGLSKRPTATMCVVGGYYWHPLSEVHVWDPLTNAWLQGAEMPDHTRESYGVTSLGPDIYVTGGYRTESIEALDTVWIYNSERDEWAEGCPMLDARYYHCAVSLSGCVYALGGYRKGAPVQEAEFYDPLKKKWVPIANMIKGVGNATACVLHEVIFVTGGHYGYRGSCTYDKIQRYHSGSNEWSIVTTSPHPEYGLCSITLQNKIYFVGGQTTITDCYDPEQDEWKQMAHMLERRMECGAVVMNGCIYVTGGYSYSKGTYLQSIEKYNPELNTWEAVGNLPSAMRSHGCVCVYNV", "length": 558, "header": "tr|A0A8V0ZNI2-1|A0A8V0ZNI2_CHICK Isoform 1 of Kelch like family member 23 OS=Gallus gallus OX=9031 GN=KLHL23 PE=4 SV=1 CANONICAL=A0A8V0ZNI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI2/entry#A0A8V0ZNI2-1", "sequence": { "sequence": "MALPGQEDYEFAYRDSSHPVCLLDAFRAFYLDGLFTDIALQAASGVLLHCHRAVLAACSSYFRAMFTADMKEKSKNQIRLPELSHAVLEALVNYAYTSQIQITKRNVQSLLQAADLLQFVSVKRACEQFLIRHLDADNCLGMHAFAEHHNCLELEKESRRMLLWQFEEVWKQEEFLDVSKEKLAFILSRENLNVWKEEAAVGAVVRWVAHNVEERIEDIYELLSCIKLDLDNVYLRSALSLQKKCRLNDNKIRSLVYSALNPSPKGLSKRPTATMCVVGGYYWHPLSEVHVWDPLTNAWLQGAEMPDHTRESYGVTSLGPDIYVTGGYRTESIEALDTVWIYNSERDEWAEGCPMLDARYYHCAVSLSGCVYALGGYRKGAPVQEAEFYDPLKKKWVPIANMIKGVGNATACVLHEVIFVTGGHYGYRGSCTYDKIQRYHSGSNEWSIVTTSPHPEYGLCSITLQNKIYFVGGQTTITDCYDPEQDEWKQMAHMLERRMECGAVVMNGCIYVTGGYSYSKGTYLQSIEKYNPELNTWEAVGNLPSAMRSHGCVCVYNV", "length": 558, "header": "tr|A0A8V0ZNI2-1|A0A8V0ZNI2_CHICK Isoform 1 of Kelch like family member 23 OS=Gallus gallus OX=9031 GN=KLHL23 PE=4 SV=1 CANONICAL=A0A8V0ZNI2-1" }, "locus": { "chromosome": "7", "start_pos": 18212368, "end_pos": 18208689, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057564.1", "url": "https://www.ensembl.org/id/ENSGALT00010057564.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034966.1", "url": "https://www.ensembl.org/id/ENSGALP00010034966.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:429025", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429025", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW57-1", "protein_name": "Kelch-like family member 23", "gene_name": "Klhl23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVRCGPAMALKGQEDYIYLFKDSSHPVDFLDAFRTFYMDGLFTDITLQCPSGIIFHCHRAVLAACSNYFKAMFTADMKEKFKSKIKLSGIHHDILEGLVNYAYTSQIEITKRNVQSLLEAADLLQFLSVKKACEQFLVRHLDIDNCIGMHSFAEFHVCSELEKESRRILCSRFKEVWQQEEFLEISLEKFLFILSRKNLSVWKEEAILEPVIKWTAHDVENRVECLYNLLSYVNIDIDPVYLKTALGLQRSCLLTENKIRSLIYNALNPMHKEISQRSTATMYIIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIDALDTVWIYNSEGDEWTEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPLKEKWLPIANMIKGVGNATACVLHEVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLITASPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWRETAPMMERRMECGAVIMNGCIYVTGGYSYSKGTYLQSIEKYDPDLNKWEIVGNLPSAMRSHGCVCVYNV", "length": 566 }, "evidence": [ { "id": "A0A8V0ZNI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZNI2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A286ZIG7-1", "protein_name": "Kelch like family member 23", "gene_name": "KLHL23", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALKGQEDYIYLFKDSAHPVDFLDAFRTFYLDGLFTDITLQCPSGIIFHCHRAVLAACSNYFKAMFTADMKEKFKNKIKISGIHHDILEGLVNYAYTSQIEITKRNVQSLLEAADLLQFLSVKKACEQFLVRHLDIDNCIGMHSFAEFHMCTELEKESRRILCSRFKEVWQQEEFLEISLEKFLFILSRKNLSVWKDEAIIEPVIKWTAHDVENRIECLYNLLSYVNIDIDPVYLKTALGLHRSCLLTENKIRSLIYNALNPMHKEISQRSTATMYIIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIEALDTVWIYNSESDEWTEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPLKEKWIPIANMIKGVGNATACVLHEVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLITSSPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWREIAPMMERRMECGAVIMNGCIYVTGGYSYSKGTYLQSIEKYDPDLNKWEIVGNLPSAMRSHGCVCVYNV", "length": 558 }, "evidence": [ { "id": "A0A8V0ZNI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZNI2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E7FED5-1", "protein_name": "Kelch-like protein 23 isoform X2", "gene_name": "klhl23", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGNAQSGYSYDFYDASHPSEVLEALHEFHNSGLFTDIALQSSSGQLFHCHKAVLSARSSYFKVMFTLDMRERANDTINLPCVDGEILGALVTYVYTAKIGITQNNVQRLLEAADLLQFNSLKKACENFLIRLLDVDNCLGMHSFAELHVCSALERAALRIILSRFEDVTLQDEFPETGFQKLMAILSTENLNVWKDTTLLDAVVKWVVYDVASRIDHIQELLNCIHINVDDVYLKMALDLRKCCSESKLRSLILTSLKPSKGFSDCCKKPTCSLYVIGGYYWHPLCEVHMWDPVSNTWVQGKDMPDFARESYSVVLLGADIYVTGGYRTETVDALDNVWIYNTDSDEWTEGCPMITARYYHCSVALRGCVYVIGGYTAGAPTQETEFYDPLKKTWFPVAEMIQGVGNATACVVNDRVYVTGGHYGYRGTCTYEKIQTYRPDINEWSITTICPHPEYGLCSVSLYNKLYLVGGQTTITDCYDPERDEWRQMCAMKERRMECGSAVINGCIYVAGGYSYSKGTYLQSIERYDPEIDCWEIVGNLPSAARSHGCVCVFGV", "length": 558 }, "evidence": [ { "id": "A0A8V0ZNI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZNI2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3GU91-1", "protein_name": "Kelch-like protein 23", "gene_name": "Klhl23", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALKGQEDYIYLFKDSSHPVDFLDAFRTFYLDGLFTDITLQCPSGIIFHCHRVVLAACSNYFKAMFTADMKEKFKSKIKLFGIHHDILEGLVNYAYTSQIEITKRNVQSLLEAADLLQFLSVKKACEQFLVRHLDIDNCIGMHSFAEFHVCSELEKESRRILCSRFKEVWQQEEFLEISLEKFLFILSRKNLNVWKEDAVIEPVIKWTAHDVENRIECLCNLLSYINIDIDPVYLKTALGLQRSCLLTENKIRSLIYNALNPMHKEISQRSTATMYIIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIDALDTVWIYNSEGDEWSEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPLKEKWLPIANMIKGVGNATACVLHEVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLITASPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWRETAPTMERRMECGAVIMNGCIYVTGGYSYSKGTYLQSIERYDPDLNKWEIVGNLPSAMRSHGCVCVYNV", "length": 558 }, "evidence": [ { "id": "A0A8V0ZNI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZNI2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6GQU2-1", "protein_name": "Kelch-like protein 23", "gene_name": "Klhl23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALKGQEDYIFHFKDSSHPVDFLDAFRTFYMDGLFTDITLQCPSGIIFHCHRAVLAACSNYFKAMFTADMKEKFKSKIKLSGIHHDILEGLVNYAYTSQIEITKRNVQSLLEAADLLQFLSVKKACEQFLVRHLDIDNCIGMHSFAEFHVCSELEKESRRILCSRFKEVWQQEEFLEISLEKFLFILSRKNLSVWKEEAILEPVIKWTAHDVENRIECIYNLLSYINIDIDPVYLKTALGLQRSCLLTENKIRSLIYNALNPMHKEISQRSTATMYIIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIDALDTVWIYNSEGDEWTEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPLKEKWLPIANMIKGVGNATACVLHEVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLITASPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWRETAPMMERRMECGAVIMNGCIYVTGGYSYSKGTYLQSIEKYDPDLNKWEIVGNLPSAMRSHGCVCVYNV", "length": 558 }, "evidence": [ { "id": "A0A8V0ZNI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZNI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NBE8-1", "protein_name": "Kelch-like protein 23", "gene_name": "KLHL23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKGQEDYIYLFKDSTHPVDFLDAFRTFYLDGLFTDITLQCPSGIIFHCHRAVLAACSNYFKAMFTADMKEKFKNKIKLSGIHHDILEGLVNYAYTSQIEITKRNVQSLLEAADLLQFLSVKKACERFLVRHLDIDNCIGMHSFAEFHVCPELEKESRRILCSKFKEVWQQEEFLEISLEKFLFILSRKNLSVWKEEAIIEPVIKWTAHDVENRIECLYNLLSYINIDIDPVYLKTALGLQRSCLLTENKIRSLIYNALNPMHKEISQRSTATMYIIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIEALDTVWIYNSESDEWTEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPLKEKWIPIANMIKGVGNATACVLHDVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLITSSPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWREIAPMMERRMECGAVIMNGCIYVTGGYSYSKGTYLQSIEKYDPDLNKWEIVGNLPSAMRSHGCVCVYNV", "length": 558 }, "evidence": [ { "id": "A0A8V0ZNI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZNI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI2" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNI2" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 104, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 408, "end_pos": 410 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNJ0-1", "uniprot_ac": "A0A8V0ZNJ0", "uniprot_id": "A0A8V0ZNJ0_CHICK", "mass": { "chemical_mass": 60680.0, "monoisotopic_mass": 60680.0 }, "refseq": {}, "gene_names": [ { "name": "CYP20A1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ0" } ] } ], "protein_names": [ { "name": "Cytochrome P450 family 20 subfamily A member 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYP20A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ0", "locus": { "chromosome": "7", "start_pos": 13282800, "end_pos": 13296245, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022116", "url": "https://www.ensembl.org/id/ENSGALG00010022116" } ] } } ], "crossref": [ { "id": "A0A8V0ZNJ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20627", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20627", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": 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This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_425229.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425229", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425229" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC427656", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZNJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "427656", "url": "https://www.ncbi.nlm.nih.gov/gene/427656", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427656", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427656", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RTEGHDK", "url": "https://omabrowser.org/oma/group/RTEGHDK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNJ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZNJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11829:SF211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11829:SF211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_425229", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425229", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFDNTQYPYNCFNYDGDDYPTCSSDEEKKFTRPAYSYIALIAMAIQQSPSNKVTLSGIYDFIMKKFPYYRSNQRAWQNSIRHNLSLNSCFVKVPRTEGNEKGKGNYWSFATGCESMLDLFENGNYRRRRRRRNMKKEHKEQRSSRGKGSSSPDTSPTDTALNSTSSSESIHERIGSEPRLLEPRGFAPNSTASRQSLSSSSLEKADSEIKFSIDYILSAPDPLPVLRSQYNMQENKYHLLEAQQINLHLWTM", "length": 252, "header": "tr|A0A8V0ZNJ5-1|A0A8V0ZNJ5_CHICK Isoform 1 of Forkhead box L3 OS=Gallus gallus OX=9031 GN=LOC427656 PE=4 SV=1 CANONICAL=A0A8V0ZNJ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5/entry#A0A8V0ZNJ5-1", "sequence": { "sequence": "MFDNTQYPYNCFNYDGDDYPTCSSDEEKKFTRPAYSYIALIAMAIQQSPSNKVTLSGIYDFIMKKFPYYRSNQRAWQNSIRHNLSLNSCFVKVPRTEGNEKGKGNYWSFATGCESMLDLFENGNYRRRRRRRNMKKEHKEQRSSRGKGSSSPDTSPTDTALNSTSSSESIHERIGSEPRLLEPRGFAPNSTASRQSLSSSSLEKADSEIKFSIDYILSAPDPLPVLRSQYNMQENKYHLLEAQQINLHLWTM", "length": 252, "header": "tr|A0A8V0ZNJ5-1|A0A8V0ZNJ5_CHICK Isoform 1 of Forkhead box L3 OS=Gallus gallus OX=9031 GN=LOC427656 PE=4 SV=1 CANONICAL=A0A8V0ZNJ5-1" }, "locus": { "chromosome": "14", "start_pos": 1815045, "end_pos": 1813273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053806.1", "url": "https://www.ensembl.org/id/ENSGALT00010053806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032391.1", "url": "https://www.ensembl.org/id/ENSGALP00010032391.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427656", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427656", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1W2PRP0-1", "protein_name": "Forkhead box protein L3", "gene_name": "FOXL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFDSSQYPYNCFNYDADDYPAGSSDEDKRLTRPAYSYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFVKVPRSEGHEKGKGNYWTFAGGCESLLDLFENGNYRRRRRRRGPKREGPRGPRAGGAQGPSGPSEPPAAQGRLAPDSAGEGAPGREPPASPAPPGKEHPRDLKFSIDYILSSPDPFPGLKPPCLAQEGRYPRLENVGLHFWTM", "length": 233 }, "evidence": [ { "id": "A0A8V0ZNJ5", "url": "https://omabrowser.org/oma/group/A0A8V0ZNJ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A3L7HPZ3-1", "protein_name": "Forkhead box L3", "gene_name": "Foxl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFDSSQYPYNCFNDDADDYPAGSSDEEKRLTRPAYSYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFVKVPRTEGHDKGKGNYWTFAGGCESLLDLFENGNFRRRRRRRGPKREGTQGPLEPAAPGSPGPDNAQAPDRGARVSPATHRDIKFSIDYILSSPDPFPALRSPCHSQEVRYPALDTQQMSFHFWAA", "length": 216 }, "evidence": [ { "id": "A0A8V0ZNJ5", "url": "https://omabrowser.org/oma/group/A0A8V0ZNJ5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LTI9-1", "protein_name": "Forkhead box protein G1", "gene_name": "Foxl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMTLTTILPAAPTRKSGSQGQHTGDPGGRFQGSHRSGRGLCHQNLTKTRESYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFVKVPRTEGHDKGKGNYWTFAGGCESLLDLFENGNFRRRRRRRGPKSEEAPGPLQPAARGSPGPDGTQAPDREAQARLVTHRDIKFSIDYILSSPDPFPVLRSSCHSQEARLSRETQSFIWRDMETFL", "length": 232 }, "evidence": [ { "id": "A0A8V0ZNJ5", "url": "https://omabrowser.org/oma/group/A0A8V0ZNJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F8H3-1", "protein_name": "Forkhead box L3", "gene_name": "foxl3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMFDSSQYPYNCFNYDGEGYPSCGTDEEKKVCRPAYSYIALIAMAIQQSPENKVTLSGIYEFIMKRFPYYRSNQRAWQNSIRHNLSLNSCFIKVPRTEGNEKGKGNYWTFATGCESMLDLFENGNFRRRRRRRNLKMGLKEPTEAFISMDAHQAVAVRSSDSDSFMNTSHRAAQNKPETEIKFSIDYILSTPDPLPAFRAPNSAIPHLEPQHLNLHFWTM", "length": 220 }, "evidence": [ { "id": "A0A8V0ZNJ5", "url": "https://omabrowser.org/oma/group/A0A8V0ZNJ5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "J3QP53-1", "protein_name": "Forkhead box L3", "gene_name": "Foxl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFDSSQYPYNCFNDDADDYPAGSSDEEKRLTRPAYSYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFVKVPRTEGNDKGKGNYWTFAGGCESLLDLFENGNFRRRRRRRGPKREEAPGPLEPTARGSPGPDSAQAPDHEAQASPTTHRDIKFSIDYILSSPDPFPTLRSSCHSQEARYPALEPQQMSFQFWAA", "length": 216 }, "evidence": [ { "id": "A0A8V0ZNJ5", "url": "https://omabrowser.org/oma/group/A0A8V0ZNJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNJ5" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 130, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNK1-1", "uniprot_ac": "A0A8V0ZNK1", "uniprot_id": "A0A8V0ZNK1_CHICK", "mass": { "chemical_mass": 51589.0, "monoisotopic_mass": 51589.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Internexin neuronal intermediate filament protein alpha", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK1", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZNK1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR45652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45652:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45652:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZNK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "RRGGSIAHARLQPRPLRAPGSGKSVRGRRLGAGGKGASRSAAARLASLLSAAMSYSVEPPALAASSRRLLAQSPRRTEGAEPRRASEKEQLRGLNERFAGYIERVRALEERNRALAGELAELRRLPPEPRRLGQLLGGELRALRARLEEAHGERAQAALERARLAEETQRLRARCEEEARGRAEAEQALRARQQAADGAARARADLERRAEALREELAELRRAHAEQLAQLGAALRAAAPPASGPPTARPDLAAALRELRAQYEALPARNLQAAEDWYRARCASLHERAARSQEAVRASRREAGECRRQLQARVVEMESLRGAHESLERQLQELEERHSAEAAGLQVSGSPPSRAALPSDPPHPRLVSRHRDPHLKPLCLCCACRKLLEGEENLFSMGSVGLPAMNPLPNPTYSFQPRSSTPSFKKEEQREAVRATSKIPSGQAGVLDGTITTAKRTERFNVHGGIIANAKV", "length": 472, "header": "tr|A0A8V0ZNK1-1|A0A8V0ZNK1_CHICK Isoform 1 of Internexin neuronal intermediate filament protein alpha OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZNK1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNK1-1", "url": 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{ "id": "A0A8V0ZNN1", "url": "https://www.orthodb.org/?gene=A0A8V0ZNN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1F4", "url": "https://www.orthodb.org/?gene=A0A8V1A1F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28422", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28422:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28422:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17663", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17663", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZNM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1F4", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1F4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKRHSEPLNAVLFHKLPRLEAEPDPGIPSMLCKPNPAPTAGPETHLGYKGSYFSCPQVEGQLLHCLLRQPHSPTGRPGAEQGKNHPMWDPLVAQDKWPSHQGHPFPLKKPPAVPKPVYAAPLCFSPLSSQGGDTLQRGPGAVSAVPPPSPVTLSHYYTAFEKYRGPPAVHDQGKAPEIPTCIPDPWMKAHREHPSASYPQPPYPQPPGSFSYKAFGFMVNGKSPPFPSTYLKPSAPRSHYPSPSDGFVSRLDAPGTLPSLKAMGPPRDPEPPPLPPARYLHPNPGFAFSPMDAALFAEHHSDGRMAPLEAHGGRVVTRHGSAFHPIHAPQKTPDGLLGPFPKGEAGYSLDKAMTANPVPCQQQVAKGGVGDATKEHFTPRGAICPQERLRDRWSGDVSPPSPPMPVINKVFSLAPYREYLEGTEGSTDVPKEHPRGDTPPQTASSGQEPAGIKVTSSSLRGEGESCHQKIPEGPKAKPVSPKPPAGCHPGLQDSGGEPTPGDVALDLSLKKSLVTTGSTQTEGMLDSGEKEGPLGRVEVGEDTNVPPQLVEAGGDTKPQVPPNRVEVGEDTKAQVPAQLVEVSSKDRSHFQSSAAFMFKKYKILKSWGSPCAPQPSSLPHAWQRSPSTSVPQEPCHNPKPVDMAPVLPQAPVPTPCHIPAQPCVANQGFSALHTSLCRIISCSVSASSPELLRDWLRRTEPGEALAETPTSPPKTKNGSKLPEPKKPLKGKEIWLAFRNAAALLSKLLAQLEAFTFTRKCPFPSVLRAGAIFIPIHVVKEKLFPELPGASVDQVLQKHKVELRPTTLSEEKLLRELELKGCTSRMLKLLALKQLPEIYPDLLNLLWHHSIQQQLGI", "length": 858, "header": "tr|A0A8V0ZNN1-1|A0A8V0ZNN1_CHICK Isoform 1 of Mucin 1, cell surface associated OS=Gallus gallus OX=9031 GN=C15orf39 PE=4 SV=1 CANONICAL=A0A8V0ZNN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNN1/entry#A0A8V0ZNM1-1", "sequence": { "sequence": "MWDPLVAQDKWPSHQGHPFPLKKPPAVPKPVYAAPLCFSPLSSQGGDTLQRGPGAVSAVPPPSPVTLSHYYTAFEKYRGPPAVHDQGKAPEIPTCIPDPWMKAHREHPSASYPQPPYPQPPGSFSYKAFGFMVNGKSPPFPSTYLKPSAPRSHYPSPSDGFVSRLDAPGTLPSLKAMGPPRDPEPPPLPPARYLHPNPGFAFSPMDAALFAEHHSDGRMAPLEAHGGRVVTRHGSAFHPIHAPQKTPDGLLGPFPKGEAGYSLDKAMTANPVPCQQQVAKGGVGDATKEHFTPRGAICPQERLRDRWSGDVSPPSPPMPVINKVFSLAPYREYLEGTEGSTDVPKEHPRGDTPPQTASSGQEPAGIKSLVTTGIEVGEDTKAQVPAQLVEVSSKDRSHFQSSAAFMFKKYKILKSWGSPCAPQPSSLPHAWQRSPSTSVPQEPCHNPKPVDMAPVLPQAPVPTPCHIPAQPCVANQGFSALHTSLCRIISCSVSASSPELLRDWLRRTEPGEALIWLAFRNAAALLSKLLAQLEAFTFTRKCPFPSVLRAGAIFIPIHVVKEKLFPELPGASVDQVLQKHKVELRPTTLSEEKLLRELELKGCTSRMLKLLALKQLPEIYPDLLNLLWHHSIQQQLGR", "length": 638, "header": "tr|A0A8V0ZNM1-1|A0A8V0ZNN1_CHICK Computationally mapped isoform of Mucin 1, cell surface associated OS=Gallus gallus OX=9031 GN=C15orf39 PE=4 SV=1 CANONICAL=A0A8V0ZNN1-1" }, "locus": { "chromosome": "10", "start_pos": 2376549, "end_pos": 2374240, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057655.1", "url": "https://www.ensembl.org/id/ENSGALT00010057655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035008.1", "url": "https://www.ensembl.org/id/ENSGALP00010035008.1" } ] } }, { "isoform_ac": "A0A8V0ZNN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNN1/entry#A0A8V0ZNN1-1", "sequence": { "sequence": "MASKRHSEPLNAVLFHKLPRLEAEPDPGIPSMLCKPNPAPTAGPETHLGYKGSYFSCPQVEGQLLHCLLRQPHSPTGRPGAEQGKNHPMWDPLVAQDKWPSHQGHPFPLKKPPAVPKPVYAAPLCFSPLSSQGGDTLQRGPGAVSAVPPPSPVTLSHYYTAFEKYRGPPAVHDQGKAPEIPTCIPDPWMKAHREHPSASYPQPPYPQPPGSFSYKAFGFMVNGKSPPFPSTYLKPSAPRSHYPSPSDGFVSRLDAPGTLPSLKAMGPPRDPEPPPLPPARYLHPNPGFAFSPMDAALFAEHHSDGRMAPLEAHGGRVVTRHGSAFHPIHAPQKTPDGLLGPFPKGEAGYSLDKAMTANPVPCQQQVAKGGVGDATKEHFTPRGAICPQERLRDRWSGDVSPPSPPMPVINKVFSLAPYREYLEGTEGSTDVPKEHPRGDTPPQTASSGQEPAGIKVTSSSLRGEGESCHQKIPEGPKAKPVSPKPPAGCHPGLQDSGGEPTPGDVALDLSLKKSLVTTGSTQTEGMLDSGEKEGPLGRVEVGEDTNVPPQLVEAGGDTKPQVPPNRVEVGEDTKAQVPAQLVEVSSKDRSHFQSSAAFMFKKYKILKSWGSPCAPQPSSLPHAWQRSPSTSVPQEPCHNPKPVDMAPVLPQAPVPTPCHIPAQPCVANQGFSALHTSLCRIISCSVSASSPELLRDWLRRTEPGEALAETPTSPPKTKNGSKLPEPKKPLKGKEIWLAFRNAAALLSKLLAQLEAFTFTRKCPFPSVLRAGAIFIPIHVVKEKLFPELPGASVDQVLQKHKVELRPTTLSEEKLLRELELKGCTSRMLKLLALKQLPEIYPDLLNLLWHHSIQQQLGI", "length": 858, "header": "tr|A0A8V0ZNN1-1|A0A8V0ZNN1_CHICK Isoform 1 of Mucin 1, cell surface associated OS=Gallus gallus OX=9031 GN=C15orf39 PE=4 SV=1 CANONICAL=A0A8V0ZNN1-1" }, "locus": { "chromosome": "10", "start_pos": 2376813, "end_pos": 2373079, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057673.1", "url": "https://www.ensembl.org/id/ENSGALT00010057673.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035018.1", "url": "https://www.ensembl.org/id/ENSGALP00010035018.1" } ] } }, { "isoform_ac": "A0A8V1A1F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNN1/entry#A0A8V1A1F4-1", "sequence": { "sequence": "MASKRHSEPLNAVLFHKLPRLEAEPDPGIPSMLCKPNPAPTAGPETHLGYKGSYFSCPQVEGQLLHCLLRQPHSPTGRPGAEQGKNHPMWDPLVAQDKWPSHQGHPFPLKKPPAVPKPVYAAPLCFSPLSSQGGDTLQRGPGAVSAVPPPSPVTLSHYYTAFEKYRGPPAVHDQGKAPEIPTCIPDPWMKAHREHPSASYPQPPYPQPPGSFSYKAFGFMVNGKSPPFPSTYLKPSAPRSHYPSPSDGFVSRLDAPGTLPSLKAMGPPRDPEPPPLPPARYLHPNPGFAFSPMDAALFAEHHSDGRMAPLEAHGGRVVTRHGSAFHPIHAPQKTPDGLLGPFPKGEAGYSLDKAMTANPVPCQQQVAKGGVGDATKEHFTPRGAICPQERLRDRWSGDVSPPSPPMPVINKVFSLAPYREYLEGTEGSTDVPKEHPRGDTPPQTASSGQEPAGIKVTSSSLRGEGESCHQKIPEGPKAKPVSPKPPAGCHPGLQDSGGEPTPGDVALDLSLKKSLVTTGSTQTEGMLDSGEKEGPLGRVEVGEDTNVPPQLVEAGGDTKPQVPPNRVEVGEDTKAQVPAQLVEVSSKDRSHFQSSAAFMFKKYKILKSWGSPCAPQPSSLPHAWQRSPSTSVPQEPCHNPKPVDMAPVLPQAPVPTPCHIPAQPCVANQGFSALHTSLCRIISCSVSASSPELLRDWLRRTEPGEALAETPTSPPKTKNGSKLPEPKKPLKGKEIWLAFRNAAALLSKLLAQLEAFTFTRKCPFPSVLRAGAIFIPIHVVKEKLFPELPGASVDQVLQKHKVELRPTTLSEEKLLRELELKGCTSRMLKLLALKQLPEIYPDLLNLLWHHSIQQQLGR", "length": 858, "header": "tr|A0A8V1A1F4-1|A0A8V0ZNN1_CHICK Computationally mapped isoform of Mucin 1, cell surface associated OS=Gallus gallus OX=9031 GN=C15orf39 PE=4 SV=1 CANONICAL=A0A8V0ZNN1-1" }, "locus": { "chromosome": "10", "start_pos": 2367814, "end_pos": 2367448, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057679.1", "url": "https://www.ensembl.org/id/ENSGALT00010057679.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035024.1", "url": "https://www.ensembl.org/id/ENSGALP00010035024.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 501, "start_aa": "Thr", "end_pos": 501, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr501", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 656, "start_aa": "Thr", "end_pos": 656, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr656", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 41, 501, 656 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 719, "end_pos": 721 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNP0-1", "uniprot_ac": "A0A8V0ZNP0", "uniprot_id": "A0A8V0ZNP0_CHICK", "mass": { "chemical_mass": 42538.0, "monoisotopic_mass": 42538.0 }, "refseq": {}, "gene_names": [ { "name": "IFFO1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP0" } ] } ], "protein_names": [ { "name": "Intermediate filament family orphan 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IFFO1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP0", "locus": { "chromosome": "1", "start_pos": 76916487, "end_pos": 76926220, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022052", "url": "https://www.ensembl.org/id/ENSGALG00010022052" } ] } } ], "crossref": [ { "id": "A0A8V0ZNP0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNP0", "url": "https://www.orthodb.org/?gene=A0A8V0ZNP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTY6", "url": "https://www.orthodb.org/?gene=A0A8V0ZTY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14516", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14516", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14516:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14516:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZNP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTY6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTY6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGTIWSFSQARRLGPGPETTLVQGPGVSWIHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRVQLQDRVTELQEEAQEAEACQEELAMKVEQLKAELVVFKGLMSNNITELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIKMFQVPASMGRKRERKQVSDEDTSLSESDASRKPDEEEEDETTAMSINEEMQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAIAAAEVQGEQQDDSLEKVIKDTESLFKSREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTPASTSESAPNEESEESDRDPPSDASIR", "length": 369, "header": "tr|A0A8V0ZNP0-1|A0A8V0ZNP0_CHICK Isoform 1 of Intermediate filament family orphan 1 OS=Gallus gallus OX=9031 GN=IFFO1 PE=4 SV=1 CANONICAL=A0A8V0ZNP0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP0/entry#A0A8V0ZNP0-1", "sequence": { "sequence": "MPGTIWSFSQARRLGPGPETTLVQGPGVSWIHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRVQLQDRVTELQEEAQEAEACQEELAMKVEQLKAELVVFKGLMSNNITELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIKMFQVPASMGRKRERKQVSDEDTSLSESDASRKPDEEEEDETTAMSINEEMQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAIAAAEVQGEQQDDSLEKVIKDTESLFKSREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTPASTSESAPNEESEESDRDPPSDASIR", "length": 369, "header": "tr|A0A8V0ZNP0-1|A0A8V0ZNP0_CHICK Isoform 1 of Intermediate filament family orphan 1 OS=Gallus gallus OX=9031 GN=IFFO1 PE=4 SV=1 CANONICAL=A0A8V0ZNP0-1" }, "locus": { "chromosome": "1", "start_pos": 76925108, "end_pos": 76917377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053619.1", "url": "https://www.ensembl.org/id/ENSGALT00010053619.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032304.1", "url": "https://www.ensembl.org/id/ENSGALP00010032304.1" } ] } }, { "isoform_ac": "A0A8V0ZTY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP0/entry#A0A8V0ZTY6-1", "sequence": { "sequence": "MKVEQLKAELVVFKGLMSNNITELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIKMFQSLHLSPVKVPASMGRKRERKQVSDEDTSLSESDASRKPDEEEEDETTAMSINEEMQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAIAAAEVQGEQDDSLEKVIKDTESLFKSREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDRKSPAFTPASTSESAPNEESEESDRDPPSDASIR", "length": 276, "header": "tr|A0A8V0ZTY6-1|A0A8V0ZNP0_CHICK Computationally mapped isoform of Intermediate filament family orphan 1 OS=Gallus gallus OX=9031 GN=IFFO1 PE=4 SV=1 CANONICAL=A0A8V0ZNP0-1" }, "locus": { "chromosome": "1", "start_pos": 76921032, "end_pos": 76917377, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053625.1", "url": "https://www.ensembl.org/id/ENSGALT00010053625.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032307.1", "url": "https://www.ensembl.org/id/ENSGALP00010032307.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP0" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 337, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNP4-1", "uniprot_ac": "A0A8V0ZNP4", "uniprot_id": "A0A8V0ZNP4_CHICK", "mass": { "chemical_mass": 88769.0, "monoisotopic_mass": 88769.0 }, "refseq": { "ac": "XP_004948511", "name": "von Willebrand factor A domain-containing protein 5A isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948511" }, "gene_names": [ { "name": "VWA5A1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP4" } ] }, { "name": "VWA5A1", "type": "synonym", "evidence": [ { "id": "XP_004948511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948511" } ] } ], "protein_names": [ { "name": "VIT domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP4/entry#names_and_taxonomy" } ] }, { "name": "von Willebrand factor A domain-containing protein 5A isoform X3", "type": "synonym", "evidence": [ { "id": "XP_004948511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948511" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052558.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004948511.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004948511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948511" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VWA5A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP4", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZNP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "419937", "url": "https://www.ncbi.nlm.nih.gov/gene/419937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNP4", "url": "https://www.orthodb.org/?gene=A0A8V0ZNP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTZ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZTZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45737", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45737", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45737:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45737:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13768", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13768", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004948511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004948511", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHQSFGLLEKSYINVPGSFLLGKEFYVPLCSLPLCSAVVDVAIQDYVADVVSELIYHNKSLRSSEVTFVFPLGPHMAIYSFQACSEDAKIKAVLQDETQQLYRGSTGEGENFDYLQYEVTESGEVFACFLGSLSPGKEMVVTLRYVQELSRKPDGAAQFMLPSTMHPYKTHYTCNCRTGKLHYSLLLTASLQSPRGVADVQANCALTPLIYTAQDHSTAQVSLAGTPPNHHLELLVYYREPTAVSVVVEKGDPVATAGSLLGDSLVLVTLAPNIHDAKPGQCKSGEFIFVLDSTSLEHAQDPLLFLLKSLPLGCYFNIYCYGATPVGIYPQSVEYTQDNLNEAMQLISTTGSRLGDTDLLGTLRTIYSTPRPCGHARQLFIFMSELPPDTEAIAAEVCHHRNSHRCFSFCFSTDSVSLATALARETDGEAVYVSSDNVIVQVLKCLKQALKPVAEGVSLEWTLPSGLEVEVLGGTPQFIFQGQHIFLYAQIHGKEQDMKEASGVMTLHFNLDGQDVTHKIQFPLCPQGDGRMAGHHLAARHLLEKLLLPEVVRGSGDEPMQRAIEISLTSGIICPFTSYVGVRTSRRAPWYHGPLALLSPRQSFVPCKILLLRGSLTDTSCFPKTIWNPPRWHTAVQESRIAIKRLINGIANLLQHGAHKEAPEQPPPSIFSLKYVDSTRFVLCSQIFGPWMNEAIAECRELVALQNVDGSWTLSSGLASVLQVEEAEIKGKMPGEVMEPSFWATVLAVTWLQRDNRRYHELCELLEAKAVTWLCSRDVSQLDKCLEASNTLLGSSVSPSVFRL", "length": 805, "header": "tr|A0A8V0ZNP4-1|A0A8V0ZNP4_CHICK Isoform 1 of VIT domain-containing protein OS=Gallus gallus OX=9031 GN=VWA5A1 PE=4 SV=1 CANONICAL=A0A8V0ZNP4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP4/entry#A0A8V0ZNP4-1", "sequence": { "sequence": "MSHQSFGLLEKSYINVPGSFLLGKEFYVPLCSLPLCSAVVDVAIQDYVADVVSELIYHNKSLRSSEVTFVFPLGPHMAIYSFQACSEDAKIKAVLQDETQQLYRGSTGEGENFDYLQYEVTESGEVFACFLGSLSPGKEMVVTLRYVQELSRKPDGAAQFMLPSTMHPYKTHYTCNCRTGKLHYSLLLTASLQSPRGVADVQANCALTPLIYTAQDHSTAQVSLAGTPPNHHLELLVYYREPTAVSVVVEKGDPVATAGSLLGDSLVLVTLAPNIHDAKPGQCKSGEFIFVLDSTSLEHAQDPLLFLLKSLPLGCYFNIYCYGATPVGIYPQSVEYTQDNLNEAMQLISTTGSRLGDTDLLGTLRTIYSTPRPCGHARQLFIFMSELPPDTEAIAAEVCHHRNSHRCFSFCFSTDSVSLATALARETDGEAVYVSSDNVIVQVLKCLKQALKPVAEGVSLEWTLPSGLEVEVLGGTPQFIFQGQHIFLYAQIHGKEQDMKEASGVMTLHFNLDGQDVTHKIQFPLCPQGDGRMAGHHLAARHLLEKLLLPEVVRGSGDEPMQRAIEISLTSGIICPFTSYVGVRTSRRAPWYHGPLALLSPRQSFVPCKILLLRGSLTDTSCFPKTIWNPPRWHTAVQESRIAIKRLINGIANLLQHGAHKEAPEQPPPSIFSLKYVDSTRFVLCSQIFGPWMNEAIAECRELVALQNVDGSWTLSSGLASVLQVEEAEIKGKMPGEVMEPSFWATVLAVTWLQRDNRRYHELCELLEAKAVTWLCSRDVSQLDKCLEASNTLLGSSVSPSVFRL", "length": 805, "header": "tr|A0A8V0ZNP4-1|A0A8V0ZNP4_CHICK Isoform 1 of VIT domain-containing protein OS=Gallus gallus OX=9031 GN=VWA5A1 PE=4 SV=1 CANONICAL=A0A8V0ZNP4-1" }, "locus": { "chromosome": "27", "start_pos": 109152, "end_pos": 101479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053632.1", "url": "https://www.ensembl.org/id/ENSGALT00010053632.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032309.1", "url": "https://www.ensembl.org/id/ENSGALP00010032309.1" } ] } }, { "isoform_ac": "A0A8V0ZTZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP4/entry#A0A8V0ZTZ1-1", "sequence": { "sequence": "MSHQSFGLLEKSYINVPGSFLLGKEFYVPLCSLPLCSAVVDVAIQDYVADVVSELIYHNKSLRSSEVTFVFPLGPHMAIYSFQACSEDAKIKAVLQDEDHSTAQVSLAGTPPNHHLELLVYYREPTAVSVVVEKGDPVATAGSLLGDSLVLVTLAPNIHDAKPGQCKSGEFIFVLDSTSLEHAQDPLLFLLKSLPLGCYFNIYCYGATPVGIYPQSVEYTQDNLNEAMQLISTTGSRLGDTDLLGTLRTIYSTPRPCGHARQLFIFMSELPPDTEAIAAEVCHHRNSHRCFSFCFSTDSVSLATALARETDGEAVYVSSDNVIVQVLKCLKQALKPVAEGVSLEWTLPSGLEVEVLGGTPQFIFQGQHIFLYAQIHGKEQDMKEASGVMTLHFNLDGQDVTHKIQFPLCPQGDGRMAGHHLAARHLLEKLLLPEVVRGSGDEPMQRAIEISLTSGIICPFTSYVGVRTSRRAPWYHGPLALLSPRQSFVPCKILLLRGSLTDTSCFPKTIWNPPRWHTAVQESRIAIKRLINGIANLLQHGAHKEAPEQPPPSIFSLKYVDSTRFVLCSQIFGPWMNEAIAECRELVALQNVDGSWTLSSGLASVLQVEEAEIKGKMPGEVMEPSFWATVLAVTWLQRDNRRYHELCELLEAKAVTWLCSRDVSQLDKCLEASNTLLGSSVSPSVFRL", "length": 688, "header": "tr|A0A8V0ZTZ1-1|A0A8V0ZNP4_CHICK Computationally mapped isoform of VIT domain-containing protein OS=Gallus gallus OX=9031 GN=VWA5A1 PE=4 SV=1 CANONICAL=A0A8V0ZNP4-1" }, "locus": { "chromosome": "27", "start_pos": 109152, "end_pos": 101479, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053638.1", "url": "https://www.ensembl.org/id/ENSGALT00010053638.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032312.1", "url": "https://www.ensembl.org/id/ENSGALP00010032312.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP4" }, { "id": "PS51468", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51468" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VIT", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 148, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNQ3-1", "uniprot_ac": "A0A8V0ZNQ3", "uniprot_id": "A0A8V0ZNQ3_CHICK", "mass": { "chemical_mass": 209548.0, "monoisotopic_mass": 209548.0 }, "refseq": {}, "gene_names": [ { "name": "PDCD11", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ3" } ] } ], "protein_names": [ { "name": "Protein RRP5 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ3/entry#names_and_taxonomy" } ] }, { "name": "Programmed cell death protein 11", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23270:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00575", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00575", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23231", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23231", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23459", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23459", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6791226", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZNQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ3-1", "database": "UniProtKB", 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"length": 1868, "header": "tr|A0A8V0ZNQ3-1|A0A8V0ZNQ3_CHICK Isoform 1 of Protein RRP5 homolog OS=Gallus gallus OX=9031 GN=PDCD11 PE=1 SV=1 CANONICAL=A0A8V0ZNQ3-1" }, "locus": { "chromosome": "6", "start_pos": 24421391, "end_pos": 24398341, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051146.1", "url": "https://www.ensembl.org/id/ENSGALT00010051146.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030337.1", "url": "https://www.ensembl.org/id/ENSGALP00010030337.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-6791226", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6791226", "resource": "Reactome", "description": "Major pathway of rRNA processing in the nucleolus and cytosol" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", 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REFSEQ: This record is predicted by automated computational analysis. 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"annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNQ6" }, { "id": "PF02441", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02441" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Flavoprotein", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 225, "start_aa": "His", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNR7-1", "uniprot_ac": "A0A8V0ZNR7", "uniprot_id": "A0A8V0ZNR7_CHICK", "mass": { "chemical_mass": 67040.0, "monoisotopic_mass": 67040.0 }, "refseq": { "ac": "XP_015152693", "name": "uncharacterized protein KIAA2013 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152693" }, "gene_names": [ { "name": "KIAA2013", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR7" } ] }, { "name": "KIAA2013", "type": "synonym", "evidence": [ { "id": "XP_015152693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152693" } ] } ], "protein_names": [ { "name": "KIAA2013", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein KIAA2013 homolog", "type": "synonym", "evidence": [ { "id": "XP_015152693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152693" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015152693.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152693" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KIAA2013", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR7", "locus": { "chromosome": "21", "start_pos": 5530968, "end_pos": 5527009, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022159", "url": "https://www.ensembl.org/id/ENSGALG00010022159" } ] } } ], "crossref": [ { "id": "A0A8V0ZNR7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNR7", "database": "AlphaFoldDB", "categories": [] }, { "id": "428195", "url": "https://www.ncbi.nlm.nih.gov/gene/428195", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428195", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428195", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LAEIHRW", "url": "https://omabrowser.org/oma/group/LAEIHRW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNR7", "url": "https://www.orthodb.org/?gene=A0A8V0ZNR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31386", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31386", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31386:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31386:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10222", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10222", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015152693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152693", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLQQRLKGLPGLLSSSWARRLLLLLLLLLVAYWYLGAGRARHGAGRGAEPRGAAALCLQAAAGPWRAQAERGDALPLPEDEAGGGPGPSLALAGNGFLLLDVAAGRLWVSVAGSGGGPSLPTEYPALVRLRALGARGEARAAQAALRDGAVRRVRCVQTGAGPGGAGECVTVREEVVAHRSRPHLYLQRIRIANPTERVATFEASAPASAPSLGARFATSLEKVEERQFLLSSGRLLLPGSPKVVLMVVAAKKLVSRVQVAPKSTFDETVLSVVYTSEPIEVSRLEETFSKLRESAKKEMLEVMQMGVEDLFQEHQQTWSDLFISGIEMRKITDSHTPSSETVNMTLYYMLSSMPAPLLDPLISGEDREKMEASLNYADHCFSGHATMHAENLWPAKLTSVPQILQLSDLWKLTLQKRGCKALVAAGVHGLMQGMVLSFGGLQFTENHLQFQADPDVLHNSYSLRGIHYNKDLINLAVLLDAEGKPFLHVSVKFQDKPVRLYACEAGCMNEPVELTSEARGHTFPVMVTQPITPLLYISTDLVHLQDLRHTLHLKAILAHEEHMAKQYPGLPFLFWFSVASLITLFHLFLFKLIYNEYCGPGAKPLFRSKV", "length": 612, "header": "tr|A0A8V0ZNR7-1|A0A8V0ZNR7_CHICK Isoform 1 of KIAA2013 OS=Gallus gallus OX=9031 GN=KIAA2013 PE=1 SV=1 CANONICAL=A0A8V0ZNR7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR7/entry#A0A8V0ZNR7-1", "sequence": { "sequence": "MWLQQRLKGLPGLLSSSWARRLLLLLLLLLVAYWYLGAGRARHGAGRGAEPRGAAALCLQAAAGPWRAQAERGDALPLPEDEAGGGPGPSLALAGNGFLLLDVAAGRLWVSVAGSGGGPSLPTEYPALVRLRALGARGEARAAQAALRDGAVRRVRCVQTGAGPGGAGECVTVREEVVAHRSRPHLYLQRIRIANPTERVATFEASAPASAPSLGARFATSLEKVEERQFLLSSGRLLLPGSPKVVLMVVAAKKLVSRVQVAPKSTFDETVLSVVYTSEPIEVSRLEETFSKLRESAKKEMLEVMQMGVEDLFQEHQQTWSDLFISGIEMRKITDSHTPSSETVNMTLYYMLSSMPAPLLDPLISGEDREKMEASLNYADHCFSGHATMHAENLWPAKLTSVPQILQLSDLWKLTLQKRGCKALVAAGVHGLMQGMVLSFGGLQFTENHLQFQADPDVLHNSYSLRGIHYNKDLINLAVLLDAEGKPFLHVSVKFQDKPVRLYACEAGCMNEPVELTSEARGHTFPVMVTQPITPLLYISTDLVHLQDLRHTLHLKAILAHEEHMAKQYPGLPFLFWFSVASLITLFHLFLFKLIYNEYCGPGAKPLFRSKV", "length": 612, "header": "tr|A0A8V0ZNR7-1|A0A8V0ZNR7_CHICK Isoform 1 of KIAA2013 OS=Gallus gallus OX=9031 GN=KIAA2013 PE=1 SV=1 CANONICAL=A0A8V0ZNR7-1" }, "locus": { "chromosome": "21", "start_pos": 5529606, "end_pos": 5527134, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053908.1", "url": "https://www.ensembl.org/id/ENSGALT00010053908.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032462.1", "url": "https://www.ensembl.org/id/ENSGALP00010032462.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428195", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428195", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58G7Z5-1", "protein_name": "Uncharacterized protein KIAA2013 homolog isoform X1", "gene_name": "si:dkeyp-104h9.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFNPPKSIWSKRQIMWLQQRLKGLPSLLSSSWARRVLVGLLVFLIFYYWFLSSDGLLKLFSMSREPGGAAGVCLQTDLHRWVSMADRGDGVVHTPQTKESGTFVVGNGHFLVDVDSNKLWVASSTQPGSAPVHQTDYSPIARLQVPGTRSEAQAMMLWYRKGSVLSSRCFQTAKSQSSRDCIVIREEFIAHRSRHNVHLQRILISNPTDHMVSVDMSLESLSFRSKMEKMDDKEFAVSSGRVLTEKKDTVLVVVATNRISNKIQVPSKSEYSANLVSVIHTSEPTEGGKLDDTLDKLRDRVRKEMVDVLRVDVEELMQEHQQAWVDLFISGVEIRKITDAHTPSSRTVNNTLYYILSTSTAPLLDQSLTSEDHEHLESSLNYADHCFSGHATMHAENLWPERLTNVAQILQLVNLWNLTLQKRGCKVLVAAGTHGMMQGMVLSFGGLQFTENHLQFQADPDVLHNSYSLRGIHYNKDLINLAVLQDIEGKPFLHVSVKPQEKPVKLYACEAGCMNEPVELTSELKGHTFPVMVTQPITPLLYISTDLTHLQDLRHTMHVKAILAHEDHMAKQYPGLPFLFWFSVASLITLFHFFLFKLIYNEYCGPGAKPLFRSKDDASV", "length": 620 }, "evidence": [ { "id": "A0A8V0ZNR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZNR7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZLT7-1", "protein_name": "RIKEN cDNA 2510039O18 gene like", "gene_name": "2510039O18Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLQQRLKGLPGLLSSSWARRLLCLLGLLLLLLWFASSGARRAAGGLHLPSWARSEPGAAEPSACLEAATRAWRGLRDRGEAVPLGPGVPALVANGFLALDAANNRLWVTPGEREPAVTPDFVPFVQLRPLNVVAEAGEAVLLLREGLLRRVRCLQLGTPGSGPAAGVPGPASASGLSTGSGRDCVLLQEDFLAHRGRPHVYLQRIQLNNPTERVAAFQTVGPTSGPVPKSFTSTLEKVGDHQFLLYSGRSTPLPSGLVHLVVVTSKKLVNRLQVAPKTQMDETVLWVVHVSAPIHPQVLKSKGTKELKALQDLARKEMLELLEMPASELLQDHQYLWAQLFSPGVEMKRITDAHTPSGLTVNLTLYYMLSCSPAPLLSPSLSHRERDQMEATLNYEDHCFSGHATMHAENLWPGQLSSVQQILQLADLWKLTLQKRGCKGLVKVGAPGILQGMVLSFGGLQFTENHLQFQADPEVLHNSYALHGIRYKNDHISLAVLADAEGKPYLHVSLESRGQPVKIYACEAGCLHDPVELTSEPGGHTFSVMVTQPITPLLYISTDLTHLQDLRHTLHLKAILAHDEHMAQQDPGLPFLFWFSVASLITLFHLFLFKLIYNEYCGPGAKPLFRSKEDPSV", "length": 634 }, "evidence": [ { "id": "A0A8V0ZNR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZNR7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KHV9-1", "protein_name": "Uncharacterized protein KIAA2013 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWLQQRLKGLPGLLSSSWARRLLCLLGLLVLLLWFAGSGARRAAGGLQLLPWPHGEPGAAEPSACLEAATHAWRSLRERGEAVLLGPGVPSLVANGFLALDVVANRLWVTPGEREPAVAPDFVPFVQLRPLSALPEAGESVLLLREGLLRRVRCLQLGTSGPGPAAAGPGPASASGLLTGSGRDCVLLQEDFLAHRGRPHVYLQRIQLNNPTERVAALQTVGPTAGPAPRAFTSTLEKVGDHQFLLYSGRSPPVPTGLVHLVVVAAKKLVDRLQVAPRTQLDETVLWVVHVSGPLNPQVLKSKAAKELKVLQDLARKEMLELLEMPAAELLQDHQRLWAQLFSPGVEMKKITDAHTPSGLTVNLTLYYMLSCSPAPLLSPDLSHRERDQMESTLNYEDHCFSGHATMHAENLWPGRLSSVQQILQLWDLWRLTLQKRGCKGLVRAGAPGILQGMVLSFGGLQFTENHLQFQADPDVLHNSYALHGIRYKNDHINLAVLADAEGKPYLHVSVESRGQLVKIYACEAGCLDEPVELTSAPQGHTFSVMVTQPITPLLYISTDLTHLQDLRHTLHLKAILAHDEHMAQQDPGLPFLFWFSVASLITLFHLFLFKLIYNEYCGPGAKPFFRNKEDPSV", "length": 634 }, "evidence": [ { "id": "A0A8V0ZNR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZNR7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IYS2-1", "protein_name": "Uncharacterized protein KIAA2013", "gene_name": "KIAA2013", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLQQRLKGLPGLLSSSWARRLLCLLGLLLLLLWFGGSGARRAAGGLHLLPWSRGEPGAAEPSACLEAATRAWRGLRERGEVVPLGPGVPALVANGFLALDVAANRLWVTPGEREPAVAPDFVPFVQLRPLSALAEAGEAVLLLREGLLRRVRCLQLGSPGPGPVAAGPGPASVSGLAAGSGRDCVLLQEDFLAHRGRPHVYLQRIQLNNPTERVAALQTVGPTAGPAPKAFTSTLEKVGDHQFLLYSGRSPPTPTGLVHLVVVAAKKLVNRLQVAPKTQLDETVLWVVHVSGPINPQVLKSKAAKELKALQDLARKEMLELLDMPAAELLQDHQLLWAQLFSPGVEMKKITDTHTPSGLTVNLTLYYMLSCSPAPLLSPSLSHRERDQMESTLNYEDHCFSGHATMHAENLWPGRLSSVQQILQLSDLWRLTLQKRGCKGLVKVGAPGILQGMVLSFGGLQFTENHLQFQADPDVLHNSYALHGIRYKNDHINLAVLADAEGKPYLHVSVESRGQPVKIYACKAGCLDEPVELTSAPTGHTFSVMVTQPITPLLYISTDLTHLQDLRHTLHLKAILAHDEHMAQQDPGLPFLFWFSVASLITLFHLFLFKLIYNEYCGPGAKPLFRSKEDPSV", "length": 634 }, "evidence": [ { "id": "A0A8V0ZNR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZNR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91X21-1", "protein_name": "Uncharacterized protein KIAA2013", "gene_name": "Kiaa2013", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLQQRLKGLPGLLSSSWARRLLCLLGLLVLLLWFASSGARRAAGGLHLPSWARSEPGAAEPSACLEAATRAWRGLRDRGEAVPLGPGVPALVANGFLALDASNNRLWVTPGEREPAVTPDFVPFVQLRPLNVVAEAGEAVLLLREGLLRRVRCLQLGTPGSGPAAGVPGPASASGLSAGSGRDCVLLQEDFLAHRGRPHVYLQRIQLNNPTERVAALQTVGPTAGPVPKSFTSTLEKVGDHQFLLYSGRSTPLPSGLVHLVVVTSKKLVNRLQVAPKTQLDETVLWVVHISGPIHPQVLKSKGAKELKALQDLARKEMLELLEMPASELLQDHQYLWAQLFSPGVEMKRITDAHTPSGLTVNLTLYYMLSCSPAPLLSPSLSHREREQMEATLNYEDHCFSGHATMHAENLWPGQLSSVQQILQLADLWKLTLQKRGCKGLVKVGAPGILQGMVLSFGGLQFTENHLQFQADPEVLHNSYALHGIRYKNDHINLAVLVDAEGKPYLHVSLESRGQPVKIYACEAGCLHDPVELTSEPGGHTFSVMVTQPITPLLYISTDLTHLQDLRHTLHLKAILAHDEHMAQQDPGLPFLFWFSVASLITLFHLFLFKLIYNEYCGPGAKPLFRSKEDPSV", "length": 634 }, "evidence": [ { "id": "A0A8V0ZNR7", "url": "https://omabrowser.org/oma/group/A0A8V0ZNR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNR7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 345, "end_pos": 347 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNS1-1", "uniprot_ac": "A0A8V0ZNS1", "uniprot_id": "A0A8V0ZNS1_CHICK", "mass": { "chemical_mass": 9353.0, "monoisotopic_mass": 9353.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "TruB pseudouridine synthase family member 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS1", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZNS1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR014780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR13767", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13767", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13767:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13767:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATGELGGRSAEKLFSLSGLFAVYKPKGPTSAAVLNLLKERLLAEAGVQTKDKKRKRQALKIGHGGTLDSAATGVLEVHCHWTTGQSY", "length": 88, "header": "tr|A0A8V0ZNS1-1|A0A8V0ZNS1_CHICK Isoform 1 of TruB pseudouridine synthase family member 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZNS1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS1/entry#A0A8V0ZNS1-1", "sequence": { "sequence": "MATGELGGRSAEKLFSLSGLFAVYKPKGPTSAAVLNLLKERLLAEAGVQTKDKKRKRQALKIGHGGTLDSAATGVLEVHCHWTTGQSY", "length": 88, "header": "tr|A0A8V0ZNS1-1|A0A8V0ZNS1_CHICK Isoform 1 of TruB pseudouridine synthase family member 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZNS1-1" }, "locus": { "chromosome": "6", "start_pos": 28865141, "end_pos": 28848103, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054775.1", "url": "https://www.ensembl.org/id/ENSGALT00010054775.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033105.1", "url": "https://www.ensembl.org/id/ENSGALP00010033105.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 30, "start_aa": "Thr", "end_pos": 30, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr30", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS1" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "pseudouridine synthesis", "id": "GO:0001522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001522", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 30 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNS6-1", "uniprot_ac": "A0A8V0ZNS6", "uniprot_id": "A0A8V0ZNS6_CHICK", "mass": { "chemical_mass": 241025.0, "monoisotopic_mass": 241025.0 }, "refseq": { "ac": "NP_001264754", "name": "basic helix-loop-helix domain-containing protein USF3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264754" }, "gene_names": [ { "name": "USF3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6" } ] }, { "name": "KIAA2018", "type": "synonym", "evidence": [ { "id": "NP_001264754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264754" } ] }, { "name": "USF3", "type": "synonym", "evidence": [ { "id": "NP_001264754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264754" } ] } ], "protein_names": [ { "name": "Upstream transcription factor family member 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6/entry#names_and_taxonomy" } ] }, { "name": "basic helix-loop-helix domain-containing protein USF3", "type": "synonym", "evidence": [ { "id": "NP_001264754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264754" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AM070924.1, CN210796.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000017.1. On Sep 23, 2021 this sequence version replaced NP_001264754.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same breed was available for the full length of the gene. The extent of this transcript is supported by partial chicken transcripts and orthologous alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264754" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "USF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6", "locus": { "chromosome": "1", "start_pos": 79314198, "end_pos": 79289344, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022508", "url": "https://www.ensembl.org/id/ENSGALG00010022508" } ] } } ], "crossref": [ { "id": "cd18910", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18910", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "418320", "url": "https://www.ncbi.nlm.nih.gov/gene/418320", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:418320", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418320", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVPDQEV", "url": "https://omabrowser.org/oma/group/CVPDQEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNS6", "url": "https://www.orthodb.org/?gene=A0A8V0ZNS6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR85", "url": "https://www.orthodb.org/?gene=A0A8V0ZR85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46970", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46970", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46970:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46970:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264754", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264754", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR85-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPAVGAPPPSPPSPPVLFSETMPEMTENDTPTKKQYRKKNRETHNAVERHRKKKINAGINRIGELIPCSPALKQSKNMILDQAFKYITEMKRQNDELLLNGGNNEQAEEIKKLRKQLDELQKENGRYIELLKANDICLYDDPTIHWKGNLKNAKVSVVIPSDQVQKNIIVYSNGSQPNGNNQGASVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVTISGIYPAENKPRSQSTVSPLAPTQVVPAGNTLELSIPENEQGVLATATASSQNASQSRTEQGLQCSSDNALQNGQSLPKSKNDEGGSKSAKKTVVQGISLPSSASMEAEKVQHMNATSSKTPNSRNEFQESSVISTTGTAVVPSVRLSTADSFSSVNVLKSTNLISSADMPTTSAAEGMKAVTVISTLPASPLENCWSFSGSTGVVPSDLKNMSSLTRMPSAGNTQTTWTTLQLAGNTVQPLSQTPSSIMTALLSEPVNGASTVSPAHSRPLTTSISLNTSLPTDGQAAEQIVVTLPSCPSLPMQPLISQPQVKTQAAGSILPLNSTMQVIQMAQPVASAVTGAPANQNVIILQPPNTAPCPPIVRAEVPSQNVSQQIVIIQAASQNPLPLLSAQPSASVRVPVNGPVAVANSSNSVQNAHLPQTFGGKHLVHILPRPSSLPSSSSTQTFSVTMSNQQHPQTISLNGQLFALQPVMSSSGASNQAPMQIIQPTTSEDPNTNVALNTFGALANLNQSISQMAGQSCLHLSLSHPTNPTTVHNQITTVNCVSLPASVPPSVPVEGSVLTSASNSTSVSPKKAAAGFLSNTKSKRTNKKQSTKKHLAANIKVSCPAIPCKDAGKADSVPVEAVAKHSKGEGLPENIPAASQALATLQVSGASISPSKEAECSEQAVGSCPVPETTLAELPTPSPLQLAVSERLALVPPTARDAAPLLPVRQSQSNPLTSTASSESSSRCEPPGTLTSSQTEAHGTSPQVSGASAVESSTAGQTSTAGTTSESCSVPQGSSVVMQDVDLLEGQGLTKMLSDLTKERTVVEKSSSFAVQGEHSNFPMESSKSVESNVDLPEKQELLLMNTEGDALSQHHTCVSDQEVVSAALIASRQADSPMSTSSGSSRGFSVASMLPDTTREDVTSNTSTSTCNNCTFSEQPDIVALAARAIFDQESLEKSGGGIQVNMRDAISKSTEVATLEREQQTFKPLPVKESNAGPLETASNKFSAQDTVQTNVDRQVEKPSCSVGGVETSNSSLQISASQSPSITSLSVNNLIHQSRIVHPLVSCSSLSQPSEPASIPATVGLSLPSSSYVNPSPRPAMMSEYAQEQLNAIRANSMQAPQLQESHLKQQNHEGRKDSAKRAVQDDLLLSTAKRQKQCQTAPLRLEGMALMNRTPEGIADQTQMLVGQMPSNSSNSVSSLSSQGHTDGLNRLFPSNSNFVTPALRQTEVQCSSQPPISEQQGTAGQHLQPIQHVPGQGISHLHNNHPYLKQQQAGQLRERHHLYQLQHHVTHGENSVHSQPHGVHQQRTIQQEVQMQKKRNLIQGTQAPQLSLQQKHHGSDQTRQKGGQPHPHHQQMQQQMQQHFGASQPEKNCENPATSRNHHNHPQSHINQDIMHQQQQDVSSRQQGSASEHVSGHNPMQRLMTSRGLEPQMVSQASIVTRPSDMTCTPHRQERNRVSSYSAEALIGKTPSNSEQRIGISLQGPRVSDQLEMRSYIDASRNKGLVIHNMQGRISIDHTVGSDVQRLSDCQTFKPAGPNQQPAGNFDVQASRNSEIGNSVSSLRGMQSQAFRIGQNTGPPIERQKRLPYQPVQGIPTGNSLPSRENENTCHQSFMQSLLAPNLGDQVSGSQRSIPEHPRNTQCGASSTIEYSCPPARESVHIRRDGDGQNRESCDMSISTINTRNSSLTIPFSTSSSSGDIQGRNTSPNISVQKSNPMRMTDSHGTKSHMNTPVSSNMHGVVRPTHPHPAVSHGNGEQGQPSVRQPNSSVTQRSRHPLQDNNSSKIRQPERNRSGNQRHGNVFDPSLPHLPLSTSSSMILGRQQSAIEKRGSIVRFMSDGPQVSNDNAASDQHTLSQNFGFPFIPEGGMNPPINANTSFIPPVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFPNPSTEKPSSGGLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTNTSHLSNFNLTSLFPEIATALPPDGSAMSPLLSIANTSASDSSKQPSNRPAHNISHILGHDCSSAV", "length": 2255, "header": "tr|A0A8V0ZNS6-1|A0A8V0ZNS6_CHICK Isoform 1 of Upstream transcription factor family member 3 OS=Gallus gallus OX=9031 GN=USF3 PE=4 SV=1 CANONICAL=A0A8V0ZNS6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6/entry#A0A8V0ZNS6-1", "sequence": { "sequence": "MVPAVGAPPPSPPSPPVLFSETMPEMTENDTPTKKQYRKKNRETHNAVERHRKKKINAGINRIGELIPCSPALKQSKNMILDQAFKYITEMKRQNDELLLNGGNNEQAEEIKKLRKQLDELQKENGRYIELLKANDICLYDDPTIHWKGNLKNAKVSVVIPSDQVQKNIIVYSNGSQPNGNNQGASVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVTISGIYPAENKPRSQSTVSPLAPTQVVPAGNTLELSIPENEQGVLATATASSQNASQSRTEQGLQCSSDNALQNGQSLPKSKNDEGGSKSAKKTVVQGISLPSSASMEAEKVQHMNATSSKTPNSRNEFQESSVISTTGTAVVPSVRLSTADSFSSVNVLKSTNLISSADMPTTSAAEGMKAVTVISTLPASPLENCWSFSGSTGVVPSDLKNMSSLTRMPSAGNTQTTWTTLQLAGNTVQPLSQTPSSIMTALLSEPVNGASTVSPAHSRPLTTSISLNTSLPTDGQAAEQIVVTLPSCPSLPMQPLISQPQVKTQAAGSILPLNSTMQVIQMAQPVASAVTGAPANQNVIILQPPNTAPCPPIVRAEVPSQNVSQQIVIIQAASQNPLPLLSAQPSASVRVPVNGPVAVANSSNSVQNAHLPQTFGGKHLVHILPRPSSLPSSSSTQTFSVTMSNQQHPQTISLNGQLFALQPVMSSSGASNQAPMQIIQPTTSEDPNTNVALNTFGALANLNQSISQMAGQSCLHLSLSHPTNPTTVHNQITTVNCVSLPASVPPSVPVEGSVLTSASNSTSVSPKKAAAGFLSNTKSKRTNKKQSTKKHLAANIKVSCPAIPCKDAGKADSVPVEAVAKHSKGEGLPENIPAASQALATLQVSGASISPSKEAECSEQAVGSCPVPETTLAELPTPSPLQLAVSERLALVPPTARDAAPLLPVRQSQSNPLTSTASSESSSRCEPPGTLTSSQTEAHGTSPQVSGASAVESSTAGQTSTAGTTSESCSVPQGSSVVMQDVDLLEGQGLTKMLSDLTKERTVVEKSSSFAVQGEHSNFPMESSKSVESNVDLPEKQELLLMNTEGDALSQHHTCVSDQEVVSAALIASRQADSPMSTSSGSSRGFSVASMLPDTTREDVTSNTSTSTCNNCTFSEQPDIVALAARAIFDQESLEKSGGGIQVNMRDAISKSTEVATLEREQQTFKPLPVKESNAGPLETASNKFSAQDTVQTNVDRQVEKPSCSVGGVETSNSSLQISASQSPSITSLSVNNLIHQSRIVHPLVSCSSLSQPSEPASIPATVGLSLPSSSYVNPSPRPAMMSEYAQEQLNAIRANSMQAPQLQESHLKQQNHEGRKDSAKRAVQDDLLLSTAKRQKQCQTAPLRLEGMALMNRTPEGIADQTQMLVGQMPSNSSNSVSSLSSQGHTDGLNRLFPSNSNFVTPALRQTEVQCSSQPPISEQQGTAGQHLQPIQHVPGQGISHLHNNHPYLKQQQAGQLRERHHLYQLQHHVTHGENSVHSQPHGVHQQRTIQQEVQMQKKRNLIQGTQAPQLSLQQKHHGSDQTRQKGGQPHPHHQQMQQQMQQHFGASQPEKNCENPATSRNHHNHPQSHINQDIMHQQQQDVSSRQQGSASEHVSGHNPMQRLMTSRGLEPQMVSQASIVTRPSDMTCTPHRQERNRVSSYSAEALIGKTPSNSEQRIGISLQGPRVSDQLEMRSYIDASRNKGLVIHNMQGRISIDHTVGSDVQRLSDCQTFKPAGPNQQPAGNFDVQASRNSEIGNSVSSLRGMQSQAFRIGQNTGPPIERQKRLPYQPVQGIPTGNSLPSRENENTCHQSFMQSLLAPNLGDQVSGSQRSIPEHPRNTQCGASSTIEYSCPPARESVHIRRDGDGQNRESCDMSISTINTRNSSLTIPFSTSSSSGDIQGRNTSPNISVQKSNPMRMTDSHGTKSHMNTPVSSNMHGVVRPTHPHPAVSHGNGEQGQPSVRQPNSSVTQRSRHPLQDNNSSKIRQPERNRSGNQRHGNVFDPSLPHLPLSTSSSMILGRQQSAIEKRGSIVRFMSDGPQVSNDNAASDQHTLSQNFGFPFIPEGGMNPPINANTSFIPPVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFPNPSTEKPSSGGLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTNTSHLSNFNLTSLFPEIATALPPDGSAMSPLLSIANTSASDSSKQPSNRPAHNISHILGHDCSSAV", "length": 2255, "header": "tr|A0A8V0ZNS6-1|A0A8V0ZNS6_CHICK Isoform 1 of Upstream transcription factor family member 3 OS=Gallus gallus OX=9031 GN=USF3 PE=4 SV=1 CANONICAL=A0A8V0ZNS6-1" }, "locus": { "chromosome": "1", "start_pos": 79313194, "end_pos": 79289416, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054783.1", "url": "https://www.ensembl.org/id/ENSGALT00010054783.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033110.1", "url": "https://www.ensembl.org/id/ENSGALP00010033110.1" } ] } }, { "isoform_ac": "A0A8V0ZR85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6/entry#A0A8V0ZR85-1", "sequence": { "sequence": "MKDLTAEEIKKLRKQLDELQKENGRYIELLKANDICLYDDPTIHWKGNLKNAKVSVVIPSDQVQKNIIVYSNGSQPNGNNQGASVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVTISGIYPAENKPRSQSTVSPLAPTQVVPAGNTLELSIPENEQGVLATATASSQNASQSRTEQGLQCSSDNALQNGQSLPKSKNDEGGSKSAKKTVVQGISLPSSASMEAEKVQHMNATSSKTPNSRNEFQESSVISTTGTAVVPSVRLSTADSFSSVNVLKSTNLISSADMPTTSAAEGMKAVTVISTLPASPLENCWSFSGSTGVVPSDLKNMSSLTRMPSAGNTQTTWTTLQLAGNTVQPLSQTPSSIMTALLSEPVNGASTVSPAHSRPLTTSISLNTSLPTDGQAAEQIVVTLPSCPSLPMQPLISQPQVKTQAAGSILPLNSTMQVIQMAQPVASAVTGAPANQNVIILQPPNTAPCPPIVRAEVPSQNVSQQIVIIQAASQNPLPLLSAQPSASVRVPVNGPVAVANSSNSVQNAHLPQTFGGKHLVHILPRPSSLPSSSSTQTFSVTMSNQQHPQTISLNGQLFALQPVMSSSGASNQAPMQIIQPTTSEDPNTNVALNTFGALANLNQSISQMAGQSCLHLSLSHPTNPTTVHNQITTVNCVSLPASVPPSVPVEGSVLTSASNSTSVSPKKAAAGFLSNTKSKRTNKKQSTKKHLAANIKVSCPAIPCKDAGKADSVPVEAVAKHSKGEGLPENIPAASQALATLQVSGASISPSKEAECSEQAVGSCPVPETTLAELPTPSPLQLAVSERLALVPPTARDAAPLLPVRQSQSNPLTSTASSESSSRCEPPGTLTSSQTEAHGTSPQVSGASAVESSTAGQTSTAGTTSESCSVPQGSSVVMQDVDLLEGQGLTKMLSDLTKERTVVEKSSSFAVQGEHSNFPMESSKSVESNVDLPEKQELLLMNTEGDALSQHHTCVSDQEVVSAALIASRQADSPMSTSSGSSRGFSVASMLPDTTREDVTSNTSTSTCNNCTFSEQPDIVALAARAIFDQESLEKSGGGIQVNMRDAISKSTEVATLEREQQTFKPLPVKESNAGPLETASNKFSAQDTVQTNVDRQVEKPSCSVGGVETSNSSLQISASQSPSITSLSVNNLIHQSRIVHPLVSCSSLSQPSEPASIPATVGLSLPSSSYVNPSPRPAMMSEYAQEQLNAIRANSMQAPQLQESHLKQQNHEGRKDSAKRAVQDDLLLSTAKRQKQCQTAPLRLEGMALMNRTPEGIADQTQMLVGQMPSNSSNSVSSLSSQGHTDGLNRLFPSNSNFVTPALRQTEVQCSSQPPISEQQGTAGQHLQPIQHVPGQGISHLHNNHPYLKQQQAGQLRERHHLYQLQHHVTHGENSVHSQPHGVHQQRTIQQEVQMQKKRNLIQGTQAPQLSLQQKHHGSDQTRQKGGQPHPHHQQMQQQMQQHFGASQPEKNCENPATSRNHHNHPQSHINQDIMHQQQQDVSSRQQGSASEHVSGHNPMQRLMTSRGLEPQMVSQASIVTRPSDMTCTPHRQERNRVSSYSAEALIGKTPSNSEQRIGISLQGPRVSDQLEMRSYIDASRNKGLVIHNMQGRISIDHTVGSDVQRLSDCQTFKPAGPNQQPAGNFDVQASRNSEIGNSVSSLRGMQSQAFRIGQNTGPPIERQKRLPYQPVQGIPTGNSLPSRENENTCHQSFMQSLLAPNLGDQVSGSQRSIPEHPRNTQCGASSTIEYSCPPARESVHIRRDGDGQNRESCDMSISTINTRNSSLTIPFSTSSSSGDIQGRNTSPNISVQKSNPMRMTDSHGTKSHMNTPVSSNMHGVVRPTHPHPAVSHGNGEQGQPSVRQPNSSVTQRSRHPLQDNNSSKIRQPERNRSGNQRHGNVFDPSLPHLPLSTSSSMILGRQQSAIEKRGSIVRFMSDGPQVSNDNAASDQHTLSQNFGFPFIPEGGMNPPINANTSFIPPVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFPNPSTEKPSSGGLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTNTSHLSNFNLTSLFPEIATALPPDGSAMSPLLSIANTSASDSSKQPSNRPAHNISHILGHDCSSAV", "length": 2153, "header": "tr|A0A8V0ZR85-1|A0A8V0ZR85_CHICK Computationally mapped isoform of Upstream transcription factor family member 3 OS=Gallus gallus OX=9031 GN=USF3 PE=4 SV=1 CANONICAL=A0A8V0ZNS6-1" }, "locus": { "chromosome": "1", "start_pos": 79313194, "end_pos": 79305924, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054777.1", "url": "https://www.ensembl.org/id/ENSGALT00010054777.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033106.1", "url": "https://www.ensembl.org/id/ENSGALP00010033106.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1432, "start_aa": "Thr", "end_pos": 1432, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1432", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 907, "start_aa": "Thr", "end_pos": 907, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr907", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:418320", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:418320", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1NA48-1", "protein_name": "Upstream transcription factor family member 3", "gene_name": "USF3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGINRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEEIQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVVIPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVSISGVYPSENKPWHQTTVSALAANQPVPLCLPAALSAQNILELSTSESESSVLGPTSSSLVAVPVGPEPPQHCSSHTCLNDQNSSENKKGQESPQVLKKTVPCATSISSSCSATATQGQPGSESCRSTQDHRSDLQTTLVVSVTTAVCSQPPRPAGDSCMASSSKGADSASVTMVVAPSVPGGGMITMPVSTLSANPMDSGWTLSCSLPSSAVSTADLKNMNSLTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESGTSPTTANHSRCVAPGISLNNSFPAEGQPVEQVVVTLPSCPPLPMQPLITQPQVKSQPPKSILPLNSAMQVIQMAQPVGSAVNAAPANQNVIILQPPSTTPCPTVMRAEVPNQTVGQQIVIIQAANQNTLPLLSAPPPGSVRLPVNGASAIIGSNNSVQNVSTPQTFGGKHLVHILPRPTSLSASNSTQTFSVTVSSQQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALASLNQSISQMAGQSCVQLSVSQPVHPQTAANSQITPANCVSLTTVAPPMTTDNSATLPSTYNLVTTPSVNTVACVPNTKAKRLNKKPGVKKHLATNKSACSLNAVRDVGKSDGPSTEGSAEPSCNDGLLESLPGVLPSAIVSQTNSVSVSGSHSLNVLNSESVMPESVPKSKSAEESSPPSQESVTSEQFTMAPAKSKDFLPISQRETSQDTPPSSLALPDAAKSCTSANVLISSADDAPVLVSQVSHLSSTTSTTSTDCVSEVGVIADPCRVQQASSDTVPTTGLLKGQGLTALLSGLAKEKDPQKSSLSVQVDHPDFSSENSKIVDSNVELHPKQELLLMSSDDRDPGQPHSCIPDQEVINGSLLTSRQADSPMSTSSGSSRSFSVASMLPETAREDVTSNAATNTCDSCTFVEQTDIVALAARAIFDQENLEKGRAGTQVPADIREVPSKPSEASSLEGDQPFKTQISKESGPGQAEATPNEFNSQDSIEATVDRPLEKPSCSVGMKTSNASLQVSTSQPPSITSLSVNNLIHQSTLSHPLVSCTGLSQTSEQTAVPTTVNLTVSSGSYGNQPPGPSLMTEYSQEHLNTMAGTVPNTPIQEPLLKPSHESRKDSTKRAVQDDLLLSSAKRQKHCQPAALRLEGLSLMSRTPDSISDQTQMMVGQIPPNSSNSVVPISNPAHGDGLTRLFPPSNNFVVPALRQTEVQCGSQASIAEQQPAQAGQHLQALQQHVPAQGVPHLHSNHVYLKQQQQAGQLRERHHLYQLQRHVPHAESSVHSQAHSVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTDQSRPKSGQPHPHHQQMQQQMQQHFGSSQAEKSCENPSTSRNHQNHLSQDILHQQEVGSRQQAPGVSSEHVSGHNPMQRLLTSRGIEQQMASQSSIVTRPSDMTCAPHRPERNRVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRVDHTASDIRLSDCQTFKPSGASQQPQNNFEVQSSRNNEIGNPVSSLRSMQPQAFRISQNPGPPPVDRQKRLPYPPVQSIPTGNAIPTRDNENTCHQSFMQSLLAPHLGDQVIGSQRSLSEHQRNTQCGPSSAVEYNCPPSHESVHIRRDSESQSRESCDMSLGAINTRNSTLNIPFSSSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSASHGNADQGPPVRQTSSSVPQRSRHPLPDSGGSKIRPPERTRSGNPRHSNVFDPSLPHLPLSTGGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSVPDQHTLSQNFGFPFIPEGGMNPPINANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFSNPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTNSHLSNFNMTSLFPEIATALPDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV", "length": 2228 }, "evidence": [ { "id": "A0A8V0ZNS6", "url": "https://omabrowser.org/oma/group/A0A8V0ZNS6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4ABR5-1", "protein_name": "Upstream transcription factor family member 3", "gene_name": "Usf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEMTEHETPTKKQHRKKNRETHNAVERHRKKKINAGINRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGSSEQAEEIKKLRKQLEEIQKENGRYIELLKANDICLYDDPTIHWKGNLKTSKVSVVIPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHGLQKQTANVVPVQRTCKLVTPVSISGIYPSENKPWHQTTVSALAANQSVPLCLPTAISAQNILELSTSESQSSALGATGGSVVTTSVGPDPHQHRSLNTCLNDQNASENSNVQESPKSSKKTVSSVSGTSSSNSAAAPGVHHETKSSLATQGSSADSQNTLVSITTPVSSQPPRSTGSSSPVSVSKTVDPTNTAAAVVPAHTAVSKSALPVSSLSATPLEGGWTLSCSLPSSSVSASELKNINSLTRISSAGNTQTTWTTLHLAGNTIQPLSQPPSSASTPALNECGTSPTPSNHKHMATGITFNNSPPTDGQPVEQIVVTLPSCPPLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQMAQPVGSGVTAAPANQNVIILQPPSTTPCPAMMRAEVSNQAVGQQIVIIQAANQNPLPLLSAPHPGPVRLPVNGASAIIGSHNSVQNVPAPQTFGGKHLVHILPRPSSLSTSNSAQTFSVTMSNQQQPQTISLNGQLFALQPVMSSSGTTNQSPMQIIQPTTSEDPNTNVALNTFGALASLNQSISQMAGQSCVQLSISQSANPQTSANSQTSPTNCVSLTTVAPTMTAENSATQSTTYSLATASSTNTVTCLPSTMKSKRLSKKPSAKKHLAANKPACPLNSVRDVGKMDGPGMDSSAEPSCSDGLLNGLPVGLSSVTVSQAKSVSISASHSLDILNSESVIPESDSKSKSAEDCSSSSRESEANEQLALATAKSKDSTPILQESSQGTPPCSVALPNATKSCASANVLTPSPTESESLVSQVSGMPSTTSTSNTVCISEVEIVAEPCPVQQESLDTMQAAGPLKGQGLTMLLSDLAKEKDLQRTSLPVQMDHPDFSPESSKIGDPNVDLHPKQELLLTSDDRDLPQPHSCLPDQEVIHGSLLTSRQADSPMSTSSGSSRSFSVASMLPETAREDVTSSTTNTCDSCTFAEQTDIVALAARAILDQESIEKGRLGTQADLKDVTPKPSETSLEGDQPFKPQIHKETCTGQADPTPNEFNSQDSVEVTVDRPLEKPSCSLGIKASNPPLQVSASQPPSLTHQNSISRPLVSCAGLSQSSDQTAIPVTVNMTVASSAYGSQPPVPPLMTEYSQEQLNSMANSIPNPQVQEPLSKPSHESRKDSAKRTVQDDLLLSSAKRQKHCQPAPLRLESVPLMSRTPDNIPDQTQMMASQITPNSSNSVVPVSNPAHGDGLTRLFPAGNNFAAPVLRQADVQCNPQPSVAEQPQQTQAGQHLQALQQHVPPQGVSHLHTNHLYLKQQQQQQQAGQLRERHHLYQLQHHVPHADNAVHSQPHIVHQQRTLQQEVQMQKKRNLVQGTPTSQLSLQPKHHGTDQSRPKSSQPHPHHQQMQQQLQQHFASSQPEKSCENPSSSRGHHSHPQNHLNQDVLHQQQDVGSRQQGSAVSSDHVSGHNPMQRLLPSRGLEQQMVSQPSIVTRSSDMTCAPHRPERNRVSSYSAEALIGKSSSTSEQRLGISIQGSRVSDQLEMRSYLDVPRNKSLALHNMQGRMDHTVTSDIRLSDCQTFKPGAASQQPQSNFEVQSSRNNEIGNPAPSLRGMQSQAFRISQNTGPPPIDRQKRLSYPPVQSIPTGNAVPPRDSENTCHQSFMQSLLAPHLGDQVIGSQRSLSEHPRNTQCGPSSTIEYNCPPARESVHIRRESESQNRESCDMSLGAINPRNSTLNIPFSSSSSSGDIQGRNTSPNVSVQKSNPMRITDSHGAKGHMNPPVTSNMHGVARPTLPHPSVSHGNADQGPPVRQANSSVAQRSRHPLQDSSGSKIRQPERNRSGNQRHSNVFDPSLPHLPLSTSGSMILGRQQPAAEKRGSIVRFMPDSPQVPNDNSGPDQHSLSQNFGFPFIPEGGMNPPINANTSFIPQVTQPSATRAPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFSNPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPEMPPMHMANSHLSNFNMTSLFPEIAALPDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV", "length": 2222 }, "evidence": [ { "id": "A0A8V0ZNS6", "url": "https://omabrowser.org/oma/group/A0A8V0ZNS6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F011-1", "protein_name": "Basic helix-loop-helix domain-containing protein USF3", "gene_name": "usf3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPEIVQNQTKNLKPPRRKKNKEIHNAVERHRKEKINAGINRIGELLPCSQALKQSKNMILAEAFRYITELKRQNDEMLLNGGDKVQAEEINRLRNQVEELRKESAHYIELLKTNDINFLDDPTIHWKGKQRCAKVAKVTPTHMISKGIIVYSNGNNSCPTSKVSIPPSPVSNLDKQPSNAVTVQPSCDISLGTGQTFGITNGAPVNNIVVTTASSHIPVATLIPAASKPCLTVVEQYSPLAPTTPRLNPPMNYITLQGLCPQPAVSTPLLPQLQPDNPTPSLTSATCPAAPLRLQHMLNLSSLPQVVMSNSVVPVAATNTTLSQNCEIQSVSTILPATATLLGTSATSSTKTTWTTLQLAGNTVQPVSQALVPDGANISHNPQQLSVCSLGTKPHEEPVSIHLQQQNPMQLQAPAPNCIAVQPSGPKPQIYSAVVPCPQAAVAQQSSILSVPAIVSQALVVHQPSVETQKAHLTHPQSCVRAQPALLPKPQLSSTLMTACNPTIQPKTPIQPAVPCQPHSQPTVLPQTPSAIVPQLHLSLMPQAQPVINPPTQPALVPKPQAATLPVLQTMQLLQVNSEETPVAVTTSPPSNSHVVILQQGSSCPTPQVIREDVTNQTPCQHIVIIQAPTLTPAPHHSHHTAIVSNATPALTSQASTSNPICTASMQAAGTKQLVHILPRPSTQLQAQAPHTITVNGQVYVLQPAKSPEKGNSLSSQSVAPVLKPTCEEPTSNVAMNCLGALTSLSQSIAKVSSQSNVQIYTIPPPSYTTVQPLLTCGSEVSTPTETVLSASVPASSSAAAGRAVKTQPQKSCGTSGNQTKQNIVRKTKLVKRKELKPGRGLRRTAVKSKALVANNLCTELSTVVTSVNSENSLNKNMVSHDANLLSSSTPSSVISTCSSSVVTSVSSSSETSTVNSVTSSLNVSIVKPSLAVGEGLKTKAKSTEVVHLHDNANVSSVNSICSTQGDVVVSTIGGSLSKGISNTGNTPQLNCSAISSTIYAQSSSVETVGTLSVASSEIHVNSSCSVTNFSETTSQNKVTNINSVCTSSERRLTESIPSFTESSTLVTNENSAQDNSKIKSLSSDLCKPPVSSDISSPSQSTSISANSVDIRPVVSIMPSKTISQTQEKYSRRDNLTETPQIQASFDATSTPDSDTSLSTQPVPLSETSRISDPLKSLKRPSSMNMPMSTTNQGNCTDIKVPESNMNTQPCKGGQSDDATEKVVTEMAAYGQKETVPPQQVCTLENDSFEPPLGTSRQTDSPLAGGSGGRGFSVASLLPAGHNISASSSTFGAFTFTSEQAEILAMAARAIFEQDSPSKRAAGCSVDIPSTAATGWDLPKIQPTLNKDNVSDQQVKLTDQADLPMSKNSSQVSAQVPPIEPLASSTTGIRLPQSIAYSQSQPSTVTSLNVNNLIRPSSNQLYPGSPNVAQQVSTSSSGGAAIMVSQSSSHIPPTCSGPSQPNEYAPLKNVLMRTNIGVGMVERHQKDMPKRSAQDDLILPNKRSKSCTAGNVARVDIKTTDHVQMMVGQMPSSTSAVMPRNHSDGVGALFSGNTFMSTVLRPTERHCLTQVSSHEQNQPSVVHLQQGHAQHNSQQSGQNLGGNPYLKHQQQQEQRHLYQLQHHLTQPESQIHSIHQRNLLQDQHGQKKRGVVRSGQTGPNVALQKQHHLEKSGVQQQHQQQQQQHQQQQQQSQQHQQQQHHQQQQSQQQQQKAQQIQQQQQSLQQQQQQQQQQMPPQSSHSRHQHIQQQIQQQHFGARQDKNCEAQQAGQRAHQNNHLVQQERPPGQDHGTMQRLMGSRSMEQQLTSQASNSVSRSSDLACTSSRQERHRLSSYSAEALIGKTPVTGEQRMGVHLQAPRNNTQDQSELRGYVDSSRGKGNIAHNSQSRLPPDHTNTTDTQRIPDCGPFKALVSSHQLSNFEVQVSRSGDMSSKSVPQIQRGPQPQAGFRMGAAPTGDGRSRGTYSGPHPVPQGVHLGPGLTREQEGCHQSFMQSLLAPHIPEQNVHQRAVQGCTPVSIEYSCVSGASVGDLQAKSSSPNLHAAQKSAPIRLGDNSKGHISQVSTNLHGPPLRTGPPHPSTPHSSSDTGRTQGSTRSLSVSQRPHHIGPDPQSTKIRPGDRPRSGNLRPGNPFEPESPLPLPSSGGVILGRTQTGSETRRSSIVRFMADGAQVSSDNNLVSDRCAVSDLTQNFGFPFIAEGGMNPPPPINANTSFIPPVTQPSASRTPALLPVEPQNTLPSFYPSYSPAAHPSLPSEIPLQYFSNQMFTSPSTDKSGSAPLNNRFGSILSPPRPVGFAQASFPLLTDITPMPIANSSGITPHLSNFNLTSLFPEIATAMPPDGSSMPMSPLLSLANTTSSDSNKQSNRPAHNISHILGHDGTSAV", "length": 2384 }, "evidence": [ { "id": "A0A8V0ZNS6", "url": "https://omabrowser.org/oma/group/A0A8V0ZNS6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SP92-1", "protein_name": "Upstream transcription factor family member 3", "gene_name": "USF3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPEMTENETPTKKQHRKKDRETHNAVERHRKKKINAGINRIGELIPCSPALKQSKNMILDQALKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEEIQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVVIPSDQVQKNIIVYSNGSQPGGNSQGTAVQGITFNVGHNLQKQTANVVPVQRTCNLVTPVSISGVYPSENKPWHQTTVSALAANQPVPLCLPATISAQNILELSTSESEPSVLVASSGSLIAVPVGPEPPQHRSLLTCLNDQNSSENKSGQESPKVLKKMVPCATSISSTCSAAATKGHHGSKSCLSIQDCRSEFQTIFVVSVTTTVCSQPPRSAGDSRPANTGKGADVTSVTAVVVPSAPGGGKTTTAVSTLSANPMDNGWTLSCSLPSSAVSASDLKNINSLTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESGTSPTTTNHSRHMATGINLNNSCPADGQPVEQVVVTLPSYPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQMAQPVGSTVNAAPANQNVIILQPPSTTPCPAVMRAEVPNQTVGQQIVIIQAANQNPLPLLSAPPPGSVRLPVNGATAIIGSNSSVQNVSTPQTFGGKHLVHILPRSSSLSTSNSTPTFSVTMSNQQQPQTISLNGQFFALQPVMSSSGTTSQAPMQIIQPTTSEDPNTNVALNTFGALASLNQSISQMAGQSCVQLPVSQPGNPQTAANSQTTPASCVSLTTTVAPPLTTDSLVTQPSTYNLVTTPSMNTVACLPNGRSKRLNKKPGVKKHSAANKSACPLNAVGDAGKLDCPSTEGPAEPSCHDGLLDGLPVVLPSVTVSQVDSVSVSGSHSLDILNSESVMPESVPKSRSAEESGLPSQDSVTSEHFTMAPAKSKDSLPVLQRETSQDKPPTSLALPDATKSCTSANVLISSAKDPHILVSQVSDLSSTTSTASTGCVSEVEIIAEPCRVEQDSSDTVPATGLLKGQGLTALLSGLAKEKDPQKSSLSVQVDHPDFASENSKIVDSSVDLHPKQELLLMSSDDRDPGPHPPCIPDQEVVNGSLLTSRQADSPMSTSSGSSRSFSVASMLPETTREDVASSATTNTCDGCTFVEQTDIVALAARAIFEQENLEKGRAGTQADIREVTSKPSEASSIEGDQTFKTQTSKENGPGRTEATANEFNSQDSIEATVDRPLEKPSCSVGIKTSNTSLQVSASQPPSITSLSVNNLIHQSSISHPLVSCTGLSQTSEQTAVPVTVNLTVSSSSYGSQPPGPSLMTEYSQEQLNTLAGTISNPQIPEPLLKPSHESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLEGLSLMSRTPDSISDQTQMMVGQIPPNSSNPVVSVSLSNPAHGDGLTRLFPPSNNFVAPALRQTEVQCSSQPSVAEQQQTQANQHLQALQQHVPAQGVPHLHSNHLYLKQQQQQQQQQQQQQQQQQQQQQQQQAGQLRERHHLYQLQHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQASQLSLQPKHHGTDQARPKSSQPHPHHQQMQQQMQQHFGSSQPEKSCENPSTSRNHHNHPQNHLNQDIMHPQQDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGIEQQMVSQPSIVTRPSDMTCTPHRPERNRVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRVDHSVASDIRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNPVSSLRGMQSQAFRIGQNPGPPPIDRQKRLPYPPVQSIPTGNALPPRDSENTCHQSFMQSLLAPHVGDQVIGSQRSLSEHQRNTQCGPSSAIEYNCPPAHESVHIRRESESQNRESCDMSLGAINTRNSTLTIPFSSSSSSGDIQGRNTSPNVSVQKSNSMRITDSHGTKGHMNPPVTTNMHGVARPALPHPSVSHGNADQGPPVRQTNSSVPQRSRHPLQDSSGSKIRQPERTRSGNQRHSNVFDPSLPHLPLATSGSMILGRQQPPAEKRGSIVRFMPESPQVPNDNAAPDQHTLSQNFGFPFIPEGGMNPPINANTSFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFSNQMFSNPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTNSHLSNFNMTSLFPEIATALPDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV", "length": 2255 }, "evidence": [ { "id": "A0A8V0ZNS6", "url": "https://omabrowser.org/oma/group/A0A8V0ZNS6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q68DE3-1", "protein_name": "Basic helix-loop-helix domain-containing protein USF3", "gene_name": "USF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPEMTENETPTKKQHRKKNRETHNAVERHRKKKINAGINRIGELIPCSPALKQSKNMILDQAFKYITELKRQNDELLLNGGNNEQAEEIKKLRKQLEEIQKENGRYIELLKANDICLYDDPTIHWKGNLKNSKVSVVIPSDQVQKKIIVYSNGNQPGGNSQGTAVQGITFNVSHNLQKQTANVVPVQRTCNLVTPVSISGVYPSENKPWHQTTVPALATNQPVPLCLPAAISAQSILELPTSESESNVLGATSGSLIAVSIESEPHQHHSLHTCLNDQNSSENKNGQENPKVLKKMTPCVTNIPHSSSATATKVHHGNKSCLSIQDFRGDFQNTFVVSVTTTVCSQPPRTAGDSSPMSISKSADLTSTATVVASSAPGVGKATIPISTLSGNPLDNGWTLSCSLPSSSVSTSDLKNINSLTRISSAGNTQTTWTTLQLAGNTIQPLSQTPSSAVTPVLNESGTSPTTSNHSRYVATDINLNNSFPADGQPVEQVVVTLPSCPSLPMQPLIAQPQVKSQPPKNILPLNSAMQVIQMAQPVGSAVNSAPTNQNVIILQPPSTTPCPTVMRAEVSNQTVGQQIVIIQAANQNPLPLLPAPPPGSVRLPINGANTVIGSNNSVQNVPTPQTFGGKHLVHILPRPSSLSASNSTQTFSVTMSNQQPQTISLNGQLFALQPVMSSSGTTNQTPMQIIQPTTSEDPNTNVALNTFGALASLNQSISQMAGQSCVQLSISQPANSQTAANSQTTTANCVSLTTTAAPPVTTDSSATLASTYNLVSTSSMNTVACLPNMKSKRLNKKPGGRKHLAANKSACPLNSVRDVSKLDCPNTEGSAEPPCNDGLLESFPAVLPSVSVSQANSVSVSASHSLGVLSSESLIPESVSKSKSAEKSSPPSQESVTSEHFAMAAAKSKDSTPNLQQETSQDKPPSSLALSDAAKPCASANVLIPSPSDPHILVSQVPGLSSTTSTTSTDCVSEVEIIAEPCRVEQDSSDTMQTTGLLKGQGLTTLLSDLAKKKNPQKSSLSDQMDHPDFSSENPKIVDSSVNLHPKQELLLMNNDDRDPPQHHSCLPDQEVINGSLINGRQADSPMSTSSGSSRSFSVASMLPETTREDVTSNATTNTCDSCTFVEQTDIVALAARAIFDQENLEKGRVGLQADIREVASKPSEASLLEGDPPFKSQIPKESGTGQAEATPNEFNSQGSIEATMERPLEKPSCSLGIKTSNASLQDSTSQPPSITSLSVNNLIHQSSISHPLASCAGLSPTSEQTTVPATVNLTVSSSSYGSQPPGPSLMTEYSQEQLNTMTSTIPNSQIQEPLLKPSHESRKDSAKRAVQDDLLLSSAKRQKHCQPAPLRLESMSLMSRTPDTISDQTQMMVSQIPPNSSNSVVPVSNPAHGDGLTRLFPPSNNFVTPALRQTEVQCGSQPSVAEQQQTQASQHLQALQQHVPAQGVSHLHSNHLYIKQQQQQQQQQQQQQQQQQAGQLRERHHLYQMQHHVPHAESSVHSQPHNVHQQRTLQQEVQMQKKRNLVQGTQTSQLSLQPKHHGTDQSRSKTGQPHPHHQQMQQQMQQHFGSSQTEKSCENPSTSRNHHNHPQNHLNQDIMHQQQDVGSRQQGSGVSSEHVSGHNPMQRLLTSRGLEQQMVSQPSIVTRSSDMTCTPHRPERNRVSSYSAEALIGKTSSNSEQRMGISIQGSRVSDQLEMRSYLDVPRNKSLAIHNMQGRVDHTVASDIRLSDCQTFKPSGASQQPQSNFEVQSSRNNEIGNPVSSLRSMQSQAFRISQNTGPPPIDRQKRLSYPPVQSIPTGNGIPSRDSENTCHQSFMQSLLAPHLSDQVIGSQRSLSEHQRNTQCGPSSAIEYNCPPTHENVHIRRESESQNRESCDMSLGAINTRNSTLNIPFSSSSSSGDIQGRNTSPNVSVQKSNPMRITESHATKGHMNPPVTTNMHGVARPALPHPSVSHGNGDQGPAVRQANSSVPQRSRHPLQDSSGSKIRQPERNRSGNQRQSTVFDPSLPHLPLSTGGSMILGRQQPATEKRGSIVRFMPDSPQVPNDNSGPDQHTLSQNFGFSFIPEGGMNPPINANASFIPQVTQPSATRTPALIPVDPQNTLPSFYPPYSPAHPTLSNDISIPYFPNQMFSNPSTEKVNSGSLNNRFGSILSPPRPVGFAQPSFPLLPDMPPMHMTNSHLSNFNMTSLFPEIATALPDGSAMSPLLTIANSSASDSSKQSSNRPAHNISHILGHDCSSAV", "length": 2245 }, "evidence": [ { "id": "A0A8V0ZNS6", "url": "https://omabrowser.org/oma/group/A0A8V0ZNS6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6" } ], "pmid": "" }, { "name": "negative regulation of epithelial to mesenchymal transition", "id": "GO:0010719", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010719", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNS6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1133, "end_pos": 1135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1141, "end_pos": 1143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1243, "end_pos": 1245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1383, "end_pos": 1385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1403, "end_pos": 1405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1897, "end_pos": 1899, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1917, "end_pos": 1919, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1921, "end_pos": 1923, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1979, "end_pos": 1981, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1993, "end_pos": 1995, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1994, "end_pos": 1996, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2004, "end_pos": 2006, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2088, "end_pos": 2090, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2190, "end_pos": 2192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2198, "end_pos": 2200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2225, "end_pos": 2227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2242, "end_pos": 2244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 733, "end_pos": 735, "annotation": "n_glycosylation_sequon" }, { "start_pos": 790, "end_pos": 792, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZNS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS6" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 91, "start_aa": "Lys", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 907, 1432 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1133, "end_pos": 1135 }, { "start_pos": 1141, "end_pos": 1143 }, { "start_pos": 1243, "end_pos": 1245 }, { "start_pos": 1383, "end_pos": 1385 }, { "start_pos": 1403, "end_pos": 1405 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 1897, "end_pos": 1899 }, { "start_pos": 1917, "end_pos": 1919 }, { "start_pos": 1921, "end_pos": 1923 }, { "start_pos": 1979, "end_pos": 1981 }, { "start_pos": 1993, "end_pos": 1995 }, { "start_pos": 1994, "end_pos": 1996 }, { "start_pos": 2004, "end_pos": 2006 }, { "start_pos": 2088, "end_pos": 2090 }, { "start_pos": 2190, "end_pos": 2192 }, { "start_pos": 2198, "end_pos": 2200 }, { "start_pos": 2225, "end_pos": 2227 }, { "start_pos": 2242, "end_pos": 2244 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 431, "end_pos": 433 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 544, "end_pos": 546 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGPSGSSFGIDTILAGGGSGSPGVMNGDFRPHGDGRPADFRSQATPSPCSEIDTVGTAPSSPVSVSMEHPEPRLAAAESLPPPPHRLHLGPHPPPAQPSPPQPPPPQLGSAGAGPRTATSSFLIKDILGDGKPLAACAPYSTSVPSPHHTPKQEGGAAPESFRPKLEQEDKAKLDKREDPQGDIKCHGTKEEGDREISSSRDSPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLGSPMPGTPHPR", "length": 367, "header": "tr|A0A8V0ZNS9-1|A0A8V0ZNS9_CHICK Isoform 1 of BarH like homeobox 2 OS=Gallus gallus OX=9031 GN=BARHL2 PE=3 SV=1 CANONICAL=A0A8V0ZNS9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNS9/entry#A0A8V0ZNS9-1", "sequence": { "sequence": "MEGPSGSSFGIDTILAGGGSGSPGVMNGDFRPHGDGRPADFRSQATPSPCSEIDTVGTAPSSPVSVSMEHPEPRLAAAESLPPPPHRLHLGPHPPPAQPSPPQPPPPQLGSAGAGPRTATSSFLIKDILGDGKPLAACAPYSTSVPSPHHTPKQEGGAAPESFRPKLEQEDKAKLDKREDPQGDIKCHGTKEEGDREISSSRDSPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLGSPMPGTPHPR", "length": 367, "header": "tr|A0A8V0ZNS9-1|A0A8V0ZNS9_CHICK Isoform 1 of BarH like homeobox 2 OS=Gallus gallus OX=9031 GN=BARHL2 PE=3 SV=1 CANONICAL=A0A8V0ZNS9-1" }, "locus": { "chromosome": "8", "start_pos": 14449068, "end_pos": 14446598, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053921.1", "url": "https://www.ensembl.org/id/ENSGALT00010053921.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032472.1", "url": "https://www.ensembl.org/id/ENSGALP00010032472.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNT4-1", "uniprot_ac": "A0A8V0ZNT4", "uniprot_id": "A0A8V0ZNT4_CHICK", "mass": { "chemical_mass": 59356.0, "monoisotopic_mass": 59356.0 }, "refseq": {}, "gene_names": [ { "name": "RSPRY1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNT4" } ] } ], "protein_names": [ { "name": "Ring finger and SPRY domain containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNT4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNT4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RSPRY1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNT4", "locus": { "chromosome": "11", "start_pos": 765188, "end_pos": 700028, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022170", "url": "https://www.ensembl.org/id/ENSGALG00010022170" } ] } } ], "crossref": [ { "id": "A0A8V0ZNT4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNT4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12883", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12883", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16566", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16566", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNT4", "url": "https://www.orthodb.org/?gene=A0A8V0ZNT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13363:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13363:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZNT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNT4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAEQKTTWSLSIGRQRAVGYVHLMEEATPGTLSDHLGGGEGLMNREGKKQNVDGLVLDTLAVIRTLVDNDQEPPYSMITLHEMAETDEGWLEVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLSGAAACQDACHPAKHRNTTAVLGCLAEKLAGPASIGLLSPGILEYLLHSLNFQSHPMVMLFALIALEKFAQTSENKMTVSESRISDQLILLEKWTDHPDYLKRQVGFCAQWSLDNLFLKEGRQFTYEKVDLTNIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDSGVWYYEVTVITSGVMQIGWATKDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHSHPCWKEGDTIGFLLDLQEKQMIFYLNGNQLPAEKQVFSSAVSGFFAAASFMSYQQCEFNFGAKPFKYPPPMKFTTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCTLCCDEVADTELRPCGHSDLCMECALQLETCPLCRQEIQTRVRQISHIS", "length": 529, "header": "tr|A0A8V0ZNT4-1|A0A8V0ZNT4_CHICK Isoform 1 of Ring finger and SPRY domain containing 1 OS=Gallus gallus OX=9031 GN=RSPRY1 PE=4 SV=1 CANONICAL=A0A8V0ZNT4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNT4/entry#A0A8V0ZNT4-1", "sequence": { "sequence": "MTAEQKTTWSLSIGRQRAVGYVHLMEEATPGTLSDHLGGGEGLMNREGKKQNVDGLVLDTLAVIRTLVDNDQEPPYSMITLHEMAETDEGWLEVVQSLIRVIPLEDPLGPAVITLLLDECPLPTKDALQKLTEILNLSGAAACQDACHPAKHRNTTAVLGCLAEKLAGPASIGLLSPGILEYLLHSLNFQSHPMVMLFALIALEKFAQTSENKMTVSESRISDQLILLEKWTDHPDYLKRQVGFCAQWSLDNLFLKEGRQFTYEKVDLTNIRAMLNSNDVSEYLKISPHGLEARCDASSFESVRCTFCVDSGVWYYEVTVITSGVMQIGWATKDSKFLNHEGYGIGDDEYSCAYDGCRQLIWYNARSKPHSHPCWKEGDTIGFLLDLQEKQMIFYLNGNQLPAEKQVFSSAVSGFFAAASFMSYQQCEFNFGAKPFKYPPPMKFTTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCTLCCDEVADTELRPCGHSDLCMECALQLETCPLCRQEIQTRVRQISHIS", "length": 529, "header": "tr|A0A8V0ZNT4-1|A0A8V0ZNT4_CHICK Isoform 1 of Ring finger and SPRY domain containing 1 OS=Gallus gallus OX=9031 GN=RSPRY1 PE=4 SV=1 CANONICAL=A0A8V0ZNT4-1" }, "locus": { "chromosome": "11", "start_pos": 729487, "end_pos": 708615, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053927.1", "url": "https://www.ensembl.org/id/ENSGALT00010053927.1" }, { "database": "Ensembl Peptide", "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZNU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVRFYPSAPTAVGSLPGADPPCLGPLDYYHCNKFDGENMYMGMNDNPQEFLSANQTYNSQNENNEDYEIPPITPPNLPDPSLLHLVDHEAGYHSLCHSLPPNSLIPAYPYQNMDLPAIMVSNMLSQDGHLLSSQLPTIQEMVHSDATSYESNRQVPLLNRPTMLAGPMGALSQSQLISQMGMRSGVTHGSPSPPGSKSATPSPSSSTQEEETESHYKVTGEKRPSTDLGKKPKSQKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGDVSKIVASMWDGLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKGSADQGETKSAQANPPSKMIPPKQPMYPMPPQASSPYPGLGSFLSPSDLQSYRGHPSLPRTLPSKPMLPSISASPPPAFQISPPLHQQLSLHHPQSSLLSQPISMQQVPQQPLLSPPMALQVQPPMNSSPPGQQDFSHISSEFSNSVGPRSPGASNPPGSTEWDNDYPSRECGINHCRPVDSGALLTHFLSSEL", "length": 515, "header": "tr|A0A8V0ZP89-1|A0A8V0ZP89_CHICK Isoform 1 of TOX high mobility group box family member 2 OS=Gallus gallus OX=9031 GN=TOX2 PE=4 SV=1 CANONICAL=A0A8V0ZP89-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89/entry#A0A8V0ZNU0-1", "sequence": { "sequence": "MDVRFYPSAPTAVGSLPGADPPCLGPLDYYHCNKTYNSQNENNEDYEIPPITPPNLPDPSLLHLVDHEAGYHSLCHSLPPNSLIPAYPYQNMDLPAIMVSNMLSQDGHLLSSQLPTIQEMVHSDATSYESNRQVPLLNRPTMLAGPMGALSQSQLISQMGMRSGVTHGSPSPPGSKSATPSPSSSTQEEETESHYKVTGEKRPSTDLGKKPKSQKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGDVSKIVASMWDGLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKGSADQGETKSAQANPPSKMIPPKQPMYPMPPQASSPYPGLGSFLSPSDLQSYRGHPSLPRTLPSKPMLPSISASPPPAFQISPPLHQQLSLHHPQSSLLSQPISMQQVPQQPLLSPPMALQVQPPMNSSPPGQQDFSHISSEFSNSVGPRSPGASNPPGSTEWDNDYPSRECGINHCRPVDSGALLTHFLSSEL", "length": 493, "header": "tr|A0A8V0ZNU0-1|A0A8V0ZP89_CHICK Computationally mapped isoform of TOX high mobility group box family member 2 OS=Gallus gallus OX=9031 GN=TOX2 PE=4 SV=1 CANONICAL=A0A8V0ZP89-1" }, "locus": { "chromosome": "20", "start_pos": 2752537, "end_pos": 2644626, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053934.1", "url": "https://www.ensembl.org/id/ENSGALT00010053934.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032482.1", "url": "https://www.ensembl.org/id/ENSGALP00010032482.1" } ] } }, { "isoform_ac": "A0A8V0ZP89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89/entry#A0A8V0ZP89-1", "sequence": { "sequence": "MDVRFYPSAPTAVGSLPGADPPCLGPLDYYHCNKFDGENMYMGMNDNPQEFLSANQTYNSQNENNEDYEIPPITPPNLPDPSLLHLVDHEAGYHSLCHSLPPNSLIPAYPYQNMDLPAIMVSNMLSQDGHLLSSQLPTIQEMVHSDATSYESNRQVPLLNRPTMLAGPMGALSQSQLISQMGMRSGVTHGSPSPPGSKSATPSPSSSTQEEETESHYKVTGEKRPSTDLGKKPKSQKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGDVSKIVASMWDGLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKGSADQGETKSAQANPPSKMIPPKQPMYPMPPQASSPYPGLGSFLSPSDLQSYRGHPSLPRTLPSKPMLPSISASPPPAFQISPPLHQQLSLHHPQSSLLSQPISMQQVPQQPLLSPPMALQVQPPMNSSPPGQQDFSHISSEFSNSVGPRSPGASNPPGSTEWDNDYPSRECGINHCRPVDSGALLTHFLSSEL", "length": 515, "header": "tr|A0A8V0ZP89-1|A0A8V0ZP89_CHICK Isoform 1 of TOX high mobility group box family member 2 OS=Gallus gallus OX=9031 GN=TOX2 PE=4 SV=1 CANONICAL=A0A8V0ZP89-1" }, "locus": { "chromosome": "20", "start_pos": 2752537, "end_pos": 2644626, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053945.1", "url": "https://www.ensembl.org/id/ENSGALT00010053945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032491.1", "url": "https://www.ensembl.org/id/ENSGALP00010032491.1" } ] } }, { "isoform_ac": "A0A8V0ZUE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89/entry#A0A8V0ZUE6-1", "sequence": { "sequence": "MDVRFYPSAPTAVGSLPGADPPCLGPLDYYHCNKFDGENMYMGMNDNPQEFLSANQTYNSQNENNEDYEIPPITPPNLPDPSLLHLVDHEAGYHSLCHSLPPNSLIPAYPYQNMDLPAIMVSNMLSQDGHLLSSQLPTIQEMVHSDATSYESNRQVPLLNRPTMLAGPMGALSQSQLISQMGMRSGVTHGSPSPPGSKSATPSPSSSTQEEETESHYKVTGEKRPSTDLGKKPKSQKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGDVSKIVASMWDGLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKGSADQGETKSAQANPPSKMIPPKQPMYPMPPQASSPYPGLGSFLSPSDLQSYRGHPSLPRTLPSKPMLPSISASPPPAFQISPPLHQQLSLHHPQSSLLSQPISMQQVPQQPLLSPPMALQVQPPMNSSPPGQQHAAKGQGTLPHLRLTICPRRLR", "length": 477, "header": "tr|A0A8V0ZUE6-1|A0A8V0ZP89_CHICK Computationally mapped isoform of TOX high mobility group box family member 2 OS=Gallus gallus OX=9031 GN=TOX2 PE=4 SV=1 CANONICAL=A0A8V0ZP89-1" }, "locus": { "chromosome": "20", "start_pos": 2752537, "end_pos": 2639411, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053923.1", "url": "https://www.ensembl.org/id/ENSGALT00010053923.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032474.1", "url": "https://www.ensembl.org/id/ENSGALP00010032474.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 201, "start_aa": "Thr", "end_pos": 201, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr201", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 74, "start_aa": "Thr", "end_pos": 74, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr74", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZP89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP89" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 247, "end_pos": 315, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 74, 201 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNV0-1", "uniprot_ac": "A0A8V0ZNV0", "uniprot_id": "A0A8V0ZNV0_CHICK", "mass": { "chemical_mass": 22653.0, "monoisotopic_mass": 22653.0 }, "refseq": {}, "gene_names": [ { "name": "ISCU", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV0" } ] } ], "protein_names": [ { "name": 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"Gallus gallus [9031]" } ], "gene": [ { "name": "ISCU", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV0", "locus": { "chromosome": "15", "start_pos": 6539377, "end_pos": 6535832, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022525", "url": "https://www.ensembl.org/id/ENSGALG00010022525" } ] } } ], "crossref": [ { "id": "A0A8V0ZNV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06664", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06664", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNV0", "url": 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"sequence": { "sequence": "MLRTSPLPAATTSRAAPRAAPCSLGCGGGGAADTSGPWPPGVLRERWWCAPLPGAGRRKMAALRAAGAALLRPGRGAAAGVGYHKKVVDHYENPRNVGSLDRNAKNVGTGLVGAPACGDVMKLQVEVDENGRIVDARFKTFGCGSAIASSSLATEWVKGKTVDEALKIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQDPKKGESEQKAN", "length": 217, "header": "tr|A0A8V0ZNV0-1|A0A8V0ZNV0_CHICK Isoform 1 of Iron-sulfur cluster assembly enzyme ISCU OS=Gallus gallus OX=9031 GN=ISCU PE=1 SV=1 CANONICAL=A0A8V0ZNV0-1" }, "locus": { "chromosome": "15", "start_pos": 6537908, "end_pos": 6536031, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054828.1", "url": "https://www.ensembl.org/id/ENSGALT00010054828.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033140.1", "url": "https://www.ensembl.org/id/ENSGALP00010033140.1" } ] } }, { "isoform_ac": "A0A8V0ZQM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV0/entry#A0A8V0ZQM8-1", "sequence": { "sequence": "MAALRAAGVGYHKKVVDHYENPRNVGSLDRNAKNVGTGLVGAPACGDVMKLQVEVDENGRIVDARFKTFGCGSAIASSSLATEWVKGKTVDEALKIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQDPKKGESEQKAN", "length": 145, "header": "tr|A0A8V0ZQM8-1|A0A8V0ZQM8_CHICK Computationally mapped isoform of Iron-sulfur cluster assembly enzyme ISCU OS=Gallus gallus OX=9031 GN=ISCU PE=1 SV=1 CANONICAL=A0A8V0ZNV0-1" }, "locus": { "chromosome": "15", "start_pos": 6537908, "end_pos": 6536208, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054824.1", "url": "https://www.ensembl.org/id/ENSGALT00010054824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033137.1", "url": "https://www.ensembl.org/id/ENSGALP00010033137.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1362409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1362409", "resource": "Reactome", "description": "Mitochondrial iron-sulfur cluster 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"url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV0" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV0" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV0" } ], "pmid": "" }, { "name": "mitochondrial [2Fe-2S] assembly complex", "id": "GO:0099128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099128", 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"ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NIF system FeS cluster assembly NifU N-terminal", "eco_id": "ECO_0000259", "start_pos": 83, "end_pos": 205, "start_aa": "Tyr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNV3-1", "uniprot_ac": "A0A8V0ZNV3", "uniprot_id": "A0A8V0ZNV3_CHICK", "mass": { "chemical_mass": 85531.0, "monoisotopic_mass": 85531.0 }, "refseq": { "ac": "XP_001232625", "name": "exocyst complex component 3-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232625" }, "gene_names": [ { "name": "EXOC3L1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3" } ] }, { "name": "EXOC3L1", "type": "synonym", "evidence": [ { "id": "XP_001232625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232625" } ] } ], "protein_names": [ { "name": "Exocyst complex component 3-like protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3/entry#names_and_taxonomy" } ] }, { "name": "exocyst complex component 3-like protein", "type": "synonym", "evidence": [ { "id": "XP_001232625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232625" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001232625.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232625" } ] }, { "annotation": "As part of the exocyst, may play a role in regulated exocytosis of insulin granules.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3#function" }, { "database": "UniProtKB", "id": "ARBA00057986", "url": "https://www.uniprot.org/uniprotkb/ARBA00057986#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXOC3L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3", "locus": { "chromosome": "11", "start_pos": 1006309, "end_pos": 1015214, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022104", "url": "https://www.ensembl.org/id/ENSGALG00010022104" } ] } } ], "crossref": [ { "id": "A0A8V0ZNV3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNV3", "database": "AlphaFoldDB", "categories": [] }, { "id": "769364", "url": "https://www.ncbi.nlm.nih.gov/gene/769364", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769364", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769364", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "REQEPNT", "url": "https://omabrowser.org/oma/group/REQEPNT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNV3", "url": "https://www.orthodb.org/?gene=A0A8V0ZNV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU37", "url": "https://www.orthodb.org/?gene=A0A8V0ZU37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21292:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21292:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001232625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232625", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU37", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU37-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGMSAKDERCASPTDEEWPEVEKAEKLARGAALKWASGVFYRPEKLEGLGHYRNRETQRNSSIQSRLKSTVQSYLEGVSTGLEQLRSAVQEVQSVCQDMGAARWALLDCADRFQGLQQMRALMAEHVQLASVVQVLPQLFSVHEVFSHTLQLLRGRRLLEAHAELMMMEHLRDDILSQLHLRGLSGAQATVLSYFSGLQELNESLAKQLWGIVGSSLQLVREDPVLFVTAVRIIEREEKIDDTLLLDATFLPPGRPKGWRQKFYHVLQETITAAHFNAVRMDAEGPGLARHLAALQRDIVAELRVVKDLMVQCVPAHYNILSVCTATYHRALSSHLQDILREDLDKQALFLLLEWVLRMYPSPEVMGHPDLLPEVDVSSLGPLVSPELVDQTERKYVEKVKASVLEWMQRTLEVEFKEWFREEEPEMDHQGFFQSALPVIVVQMLSENIQVASLITDSLQQKVYNMALEELEAFLGRLREVLVQCGKEHQKDRTVPKHYVPYLLAMLNNNLALSSSIPSLHPNAACREVPASLRAALDKIQKKACQLLLEELLLDLQPLYAQLPSRKWLSGPQLVNSMCEVIDKYTKDFSHVRKPAFTLLLMESELLVVSQYLRALMQKKMVCKSKEERGQLCERLLQDATQLRELFCSLGLDRRQQSLEAVFALQELICLKDPALLSLEVLGFITKYPDASDEHISTLLDLRGDISKDVRHLVLEMMAQNPQPLPEGYRPIFSTILVPAPEQPFCLRKAKCA", "length": 753, "header": "tr|A0A8V0ZNV3-1|A0A8V0ZNV3_CHICK Isoform 1 of Exocyst complex component 3-like protein OS=Gallus gallus OX=9031 GN=EXOC3L1 PE=3 SV=1 CANONICAL=A0A8V0ZNV3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3/entry#A0A8V0ZNV3-1", "sequence": { "sequence": "MGMSAKDERCASPTDEEWPEVEKAEKLARGAALKWASGVFYRPEKLEGLGHYRNRETQRNSSIQSRLKSTVQSYLEGVSTGLEQLRSAVQEVQSVCQDMGAARWALLDCADRFQGLQQMRALMAEHVQLASVVQVLPQLFSVHEVFSHTLQLLRGRRLLEAHAELMMMEHLRDDILSQLHLRGLSGAQATVLSYFSGLQELNESLAKQLWGIVGSSLQLVREDPVLFVTAVRIIEREEKIDDTLLLDATFLPPGRPKGWRQKFYHVLQETITAAHFNAVRMDAEGPGLARHLAALQRDIVAELRVVKDLMVQCVPAHYNILSVCTATYHRALSSHLQDILREDLDKQALFLLLEWVLRMYPSPEVMGHPDLLPEVDVSSLGPLVSPELVDQTERKYVEKVKASVLEWMQRTLEVEFKEWFREEEPEMDHQGFFQSALPVIVVQMLSENIQVASLITDSLQQKVYNMALEELEAFLGRLREVLVQCGKEHQKDRTVPKHYVPYLLAMLNNNLALSSSIPSLHPNAACREVPASLRAALDKIQKKACQLLLEELLLDLQPLYAQLPSRKWLSGPQLVNSMCEVIDKYTKDFSHVRKPAFTLLLMESELLVVSQYLRALMQKKMVCKSKEERGQLCERLLQDATQLRELFCSLGLDRRQQSLEAVFALQELICLKDPALLSLEVLGFITKYPDASDEHISTLLDLRGDISKDVRHLVLEMMAQNPQPLPEGYRPIFSTILVPAPEQPFCLRKAKCA", "length": 753, "header": "tr|A0A8V0ZNV3-1|A0A8V0ZNV3_CHICK Isoform 1 of Exocyst complex component 3-like protein OS=Gallus gallus OX=9031 GN=EXOC3L1 PE=3 SV=1 CANONICAL=A0A8V0ZNV3-1" }, "locus": { "chromosome": "11", "start_pos": 1014549, "end_pos": 1007279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053760.1", "url": "https://www.ensembl.org/id/ENSGALT00010053760.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032370.1", "url": "https://www.ensembl.org/id/ENSGALP00010032370.1" } ] } }, { "isoform_ac": "A0A8V0ZU37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3/entry#A0A8V0ZU37-1", "sequence": { "sequence": "MGMSAKDERCASPTDEEWPEVEKAEKLARGAALKWASGVFYRPEKLEGLGHYRNRETQRNSSIQSRLKSTVQSYLEGVSTGLEQLRSAVQEVQSVCQDMGAARWALLDCADRFQGLQQMRALMAEHVQLASVVQVLPQLFSVHEVFSHTLQLLRGRRLLEAHAELMMMEHLRDDILSQLHLRGLSGAQATVLSYFSGLQELNESLAKQLWGIVGSSLQLVREDPVLFVTAVRIIEREEKIDDTLLLDATFLPPGRPKGWRQKFYHVLQETITAAHFNAVRMDAEGPGLARHLAALQRDIVAELRVVKDLMVQCVPAHYNILSVCTATYHRALSSHLQDILREDLDKQALFLLLEWVLRMYPSPEVMGHPDLLPEVDVSSLGPLVSPELVDQTERKYVEKVKASVLEWMQRTLEVEFKEWFREEEPEMDHQGFFQSALPVIVVQMLSENIQVASLITDSLQQKVYNMALEELEAFLGRLREVLVQCGKEHQKDRTVPKHYVPYLLAMLNNNLALSSSIPSLHPNAACREVPASLRAALDKIQKKACQLLLEELLLDLQLLLMESELLVVSQYLRALMQKKMVCKSKEERGQLCERLLQDATQLRELFCSLGLDRRQQSLEAVFALQELICLKDPALLSLEVLGFITKYPDASDEHISTLLDLRGDISKDVRHLVLEMMAQNPQPLPEGYRPIFSTILVPAPEQPFCLRKAKCA", "length": 712, "header": "tr|A0A8V0ZU37-1|A0A8V0ZNV3_CHICK Computationally mapped isoform of Exocyst complex component 3-like protein OS=Gallus gallus OX=9031 GN=EXOC3L1 PE=3 SV=1 CANONICAL=A0A8V0ZNV3-1" }, "locus": { "chromosome": "11", "start_pos": 1014549, "end_pos": 1007279, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053748.1", "url": "https://www.ensembl.org/id/ENSGALT00010053748.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032363.1", "url": "https://www.ensembl.org/id/ENSGALP00010032363.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769364", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769364", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AV37-1", "protein_name": "Exocyst complex component 3-like protein", "gene_name": "exoc3l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDGDKNGRDNHEEALVPVEVWQELERAECLARGAALKWASGVFCRPEHLEKLGQYKKRESQRTASIQSRLKSVVQSYLEGVDWGLGQLREARAELRGVSHDLYKANLESRKNSEEVTTLETLREISVSHCQLLAAVSNLPRLYKVRSMVLETERLVESRRLLEAHARLMELERWQDEVLLQLQGPRGSSGTELNSEDEELVRNYFSGVGRLVDALAKELWAVVGSGLSLAHQNPTPFVSAVRIVEREEALDQFFLEERRSTSGHNIPMPAGRPRNWRDRFFKVMEEAVSARFRSVSYLHTRGPGLASHLSALQHCIMGDLSTVRHCLEQCVPAHYHLTRAYLHFCHQFLQTHLGLVSGWELEGGEIFAVLNWVLHIYNSSEMMGEPALLAELEIENLGPLISQEGLEQLQNKYVQKVRKSVSEWMQKALEVELTDWQRDQEPDIDHEGYYHTSLPTIITQMLEENARVALMISEALRDQTIQMGLYEMEKLLSRFRDAVIEFGKEHRKDPTVNKFYLHYLLACINNCIILKTSTESLQQQICSFVSNRYSRIPLGPLAALDRAVRKACRLVMDHLLFELQPHLQELLSSTWLDQGDVTLNMCGVLERHCELYNRVRQPCRQRLKEECQWLTVVEYVRAVMQKRLVCRSSDEQKQLAQRMTQDAQQLRDHLQSMEIDGTIGEVNPTALIAALADIINLKDPGMLLLEISGLLSKYPDISEEHVSVLLDIRGDVPKEVRKSVLDFLDQSAPPLPPGYRPIFTEILVPSSSIPFCLPTAKCT", "length": 780 }, "evidence": [ { "id": "A0A8V0ZNV3", "url": "https://omabrowser.org/oma/group/A0A8V0ZNV3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MBI4-1", "protein_name": "Exocyst complex component 3-like protein", "gene_name": "EXOC3L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSAARDKTQPALPTGLEWPEQERAEQLARGAALKWASGIFYRPEQLARLGQYRNREVQRTCSLEARIKSVVQSYLEGVKTGVWQLAQALEAVQGAREALGQARGLLRDMAEAAQTLEPLREQVVEHKQLQALSQLLPRLRAVPAAVAHTQTLIDAQRLLEAYVSLRELEQLQEETCVPLGGLELPVFEGLGPLAEALGQAVEAAAGAAGQLARENPALLVAAVRVAEVDAGCTTSLEQAPRDWRQRCLRALQQGLERVHFGTSLQPGPGELAKWLEALRVALPAELAMAEALVAPCCPPHYKVVQLWAHTLHGGLRRCLQQLLEGPELEEADTFTLLHWVLHVYQGPEMMGSLELGPEADVSDLEPLLTLENIEQLEATFVAKVQAKVAQWLQKALDGEVVEWGREQEPDTDLSGFYHSPLPAIVLQILEENIRVTRIVSVSLEQRVHGMALSELSAFLRSFTDALIRFSRDHLRGEAVVPHYVPYLLATLNHQLALSSSVSVLQPKWVVPGVLAPVEAELDKLQKRICRLVLEALLAELQPLFAALPSRRWLSSPELLDDVCKRTARFCQNFQHVRNPAVQLLLVEAERTVVLQYLSALMQGRLVCRGADERTQAAERMQHDAAQLQELFLGLGLEESVQCVPVLLALKELLNLRDPTLLGLEVAGLRQQFPDVSEDHVSALLDLRGDVSREQRLAALSSLRAGPQPSPQAGRRALFSLVPTPAPSLASCFPSGSCA", "length": 739 }, "evidence": [ { "id": "A0A8V0ZNV3", "url": "https://omabrowser.org/oma/group/A0A8V0ZNV3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RFW4-1", "protein_name": "Exocyst complex component 3-like protein", "gene_name": "EXOC3L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDSAANNKMQPAFPPGPEWPEQERAEQLARGAALKWASGVFYRPEQLARLGQYRSREVQRTCSLEARIKSVVQSYLEGVKTGVWQLARALEAVQGAREALGQARGLLRDMAEAAKTLEPLQRQVVQHKQLQAMSQLLPRLRAVPAAVAHTQTLIDAQRLLEAYVSLRELEQLQEETRAPLGGLELPVFEGLGPLAEALGQAVEEAAGAAGHLAREDPSLLVAAVRVAEVDAGHTTSLEQPPRNWRQRCLQALQGGLERIHFGTPLRPGPGALAEWLEALRVALPAELATAEALVAPCCPPHYQVVQLWAHTLHSGLRRCLQQLLEGPELEAADAFTLLHWALHVYLGPEMMGSLELGPEADVSDLEPLLTLENIEQLEATFVAKVQASVAQWLQKALDGEVAEWSRDQEPDTDPSGFYHSPMPAIVLQILEENIRVTSMVSESLQRRVHGMALSELNAFLRSFSDALIRFSRDHLRGEAMAPHYVLYLLATLNHQLALSSSVSVLQPDWVAPGTLAPVEAALDELQRRICRLVLEALLAELQPLFEALPSRRWLSSPELLDDVCKRTARFCQDFRHVRKPAVQLLLAEAEHIVVLQYLRALMQGRLVCRNAEERTQAAERLRQDAAQLQELFLSLGLEESVQCAPVLLALRELLNLRDPTLLGLEVAGLRQQFPDVSEDHVSALLDLRGDVSREQRLAALSSLQVGPQPSPQAGRRALFSLVPTPAPPLSSCLPSGSCA", "length": 739 }, "evidence": [ { "id": "A0A8V0ZNV3", "url": "https://omabrowser.org/oma/group/A0A8V0ZNV3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86VI1-1", "protein_name": "Exocyst complex component 3-like protein", "gene_name": "EXOC3L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSAAKDEMQPALSPGPEWPEQERAEQLARGAALKWASGIFYRPEQLARLGQYRSREVQRTCSLESRLKSVMQSYLEGVQTGVWQLAQAIEVVQGTREALSQARGLLQGMSQALQTLEPLRERVAQHKQLQALSHLLPRLRAVPAAVSHTQTLIDGQQFLEAYVSLRELEQLREDTWAPLGGLELPVFQGLDLLFEALGQAVEAAAGAAGKLAREDPALLVAAVRVAEVETGRTTPLGQVPRDWRQRCLRALQEGLEQAHFGSPLLPAPGALPGWLEALRVALPVELATAEALVAPCCPPQYNVVQLWAHTLHSGLRRSLQNLLAGPELEAADAFALLHWALHVYLGQEMMGSLELGPEADVSQLEPLLTLENIEQLEATFVANIQASVSQWLQNALDGEVAEWGREHGPNTDPSGSYYSPMPAIVLQILEENIRVASLVSESLQQRVHGMALSELGTFLRSFSDALIRFSRDHFRGKSMAPHYVPYLLAALNHKSALSSSVSVLQLDGAPSGALAPVEAALDELQRRIYRLVLEALQAELQPLFADLPSRQWLSSPELLQSVCERTGRFCRDFWRVRNPTVQLLLAEAERAVVLQYLSALMQGRLVCRGADERTQAAERLRHDAAQLQQLFLSLGLEENAHCAPVLLALRELLNLRDPALLGLEVAGLRQQFPDVSEDHVSALLGLRGDLSREQHLAALSSLQAALPPSPRASRRVLFSLVPAPALAPASCLPSGSCARALLLAE", "length": 746 }, "evidence": [ { "id": "A0A8V0ZNV3", "url": "https://omabrowser.org/oma/group/A0A8V0ZNV3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BI71-1", "protein_name": "Exocyst complex component 3-like protein", "gene_name": "Exoc3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSKIQPTLRPGSSCPRPEWPEQERAEQLARGAALKWASGIFYRPEQLTRLGQYRSREIQRNYSLEARIKSVVQSYLEGVQTGVWQLTRALEAVQGTREALSQAHHLLKGLSRTSQTLEPLRECVVQHKQLQILTRLLPRLQAVPATVAHTQTLIDSERLLEAYVSLRELEQLKEETLAPLGGLELPIFQGLGLLAEALGQAVEAAAGAAGRLAREDPALLVAAIRVAEVETERTILGQAPRDWRQRCLRALQEGLERVHFASPVLPEPGALAGWLEALQVALPAELATAEALVAPCCPPSYRVVELWAHTLHSGLRRSVQQLLAGPELGAADTFALLHWALHVYTGKEMMGNLELGPEADVSQLEPLLTSENIEQLEAAFVAQVQVSVAQWLKKALDGEVAEWSGEQEPPTDPSGFYHSPMPAIVLQILAENIQVTNLISDSLHRRAHNMAVSELGAFLRSFSDALIRFSRDHLRGDAVAPHYVPYLLSAFNHQSALRSSVSVLLPDGEASGVLAPVEAALDDVQRRICRLVLEVLQVELQPLFSALPSRRWLLSSELLDGVCEQTSHFCQDFWRVRKPGVQLLLAEAERTVVLQYLRALMQGRLVCRGTDERSQAAERLRQDAAQLKELFLGLGLEESAHCAPVLLALRELLNLHDPTLLGLEVAGLRQQFPDVSEDHVSALLDLRGDVSREHRQAALSSLQAGPPPSPSTGRRALFSLVPTPTPSLSSCLPSGPCS", "length": 739 }, "evidence": [ { "id": "A0A8V0ZNV3", "url": "https://omabrowser.org/oma/group/A0A8V0ZNV3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "exocyst localization", "id": "GO:0051601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3" } ], "pmid": "" }, { "name": "peptide hormone secretion", "id": "GO:0030072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030072", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNV5-1", "uniprot_ac": "A0A8V0ZNV5", "uniprot_id": "A0A8V0ZNV5_CHICK", "mass": { "chemical_mass": 70184.0, "monoisotopic_mass": 70184.0 }, "refseq": {}, "gene_names": [ { "name": "CDK5RAP3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ] } ], "protein_names": [ { "name": "CDK5 regulatory subunit associated protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDK5RAP3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5", "locus": { "chromosome": "27", "start_pos": 3692203, "end_pos": 3697086, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023706", "url": "https://www.ensembl.org/id/ENSGALG00010023706" } ] } } ], "crossref": [ { "id": "A0A8V0ZNV5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNV5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNV5", "url": "https://www.orthodb.org/?gene=A0A8V0ZNV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZW40", "url": "https://www.orthodb.org/?gene=A0A8V0ZW40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZW44", "url": "https://www.orthodb.org/?gene=A0A8V0ZW44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14894", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14894", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14894:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14894:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPPCPSCQWGSTGGPRWVGGGVGRGCGMDPNRRPCAPSQPHLSSRSPSAHSPGFSASVGLTFFFSLKRPELDTLTCFPLVLLSTIFSRRAAKSGVPSSPGASGPSPAWMSGLSYSTLGMDLRFLRKASPRDYQDVPIDIQTGKLLDWLVDRRHCGLRWQAQVSAVRQKIEAALRDMPEHEEIARLLAGAAIHYSHCLRIVDILRGTEASTKNLFGRYSSQRMKDWQEIVALYEKDNTYLAELAALLVRNVTYEVPALRKQIARCQQAQQDLARREEECQLAAAELRERFYASCKQYGITGSNVRQELLALVQDLPSLLSEVGAGVGALSEAVELYQACVEFVCQSSEGPVVPMLRYVGSKGNTTVYEWRTGFEPVKVERPEVQVVPEQPKEDTIDWGDFTLEPIGGGDIDSAAAGGEAQDNEIDWGIVVEPSPQDNGIDWGDGEGNGAQITVLEDGSEEPEAVARGSDALTLLENAATRNQFIDELMELELFLAQRLVEMEEEADVLAASQFQLAPAVLQGQTSTRVGTLLANTRALLDQLSTRRMQHLFIILASPRYVDRVSEMLQQKLNQAELLLAKREALSRKRHEALTEQGVLEPKLDRLQERTRELQQLIEADISKRYGGRPVHLMGVSL", "length": 636, "header": "tr|A0A8V0ZNV5-1|A0A8V0ZNV5_CHICK Isoform 1 of CDK5 regulatory subunit associated protein 3 OS=Gallus gallus OX=9031 GN=CDK5RAP3 PE=1 SV=1 CANONICAL=A0A8V0ZNV5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5/entry#A0A8V0ZNV5-1", "sequence": { "sequence": "MSPPCPSCQWGSTGGPRWVGGGVGRGCGMDPNRRPCAPSQPHLSSRSPSAHSPGFSASVGLTFFFSLKRPELDTLTCFPLVLLSTIFSRRAAKSGVPSSPGASGPSPAWMSGLSYSTLGMDLRFLRKASPRDYQDVPIDIQTGKLLDWLVDRRHCGLRWQAQVSAVRQKIEAALRDMPEHEEIARLLAGAAIHYSHCLRIVDILRGTEASTKNLFGRYSSQRMKDWQEIVALYEKDNTYLAELAALLVRNVTYEVPALRKQIARCQQAQQDLARREEECQLAAAELRERFYASCKQYGITGSNVRQELLALVQDLPSLLSEVGAGVGALSEAVELYQACVEFVCQSSEGPVVPMLRYVGSKGNTTVYEWRTGFEPVKVERPEVQVVPEQPKEDTIDWGDFTLEPIGGGDIDSAAAGGEAQDNEIDWGIVVEPSPQDNGIDWGDGEGNGAQITVLEDGSEEPEAVARGSDALTLLENAATRNQFIDELMELELFLAQRLVEMEEEADVLAASQFQLAPAVLQGQTSTRVGTLLANTRALLDQLSTRRMQHLFIILASPRYVDRVSEMLQQKLNQAELLLAKREALSRKRHEALTEQGVLEPKLDRLQERTRELQQLIEADISKRYGGRPVHLMGVSL", "length": 636, "header": "tr|A0A8V0ZNV5-1|A0A8V0ZNV5_CHICK Isoform 1 of CDK5 regulatory subunit associated protein 3 OS=Gallus gallus OX=9031 GN=CDK5RAP3 PE=1 SV=1 CANONICAL=A0A8V0ZNV5-1" }, "locus": { "chromosome": "27", "start_pos": 3696887, "end_pos": 3692315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057817.1", "url": "https://www.ensembl.org/id/ENSGALT00010057817.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035088.1", "url": "https://www.ensembl.org/id/ENSGALP00010035088.1" } ] } }, { "isoform_ac": "A0A8V0ZW40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5/entry#A0A8V0ZW40-1", "sequence": { "sequence": "MGYRGRGERPPRHTDPQQQGRGRGKPPGRCAVTWMWAPRGRGCSEHRDALPEPPAPLCGLRDPGDGVGPHTCCCPAAASPRDYQDVPIDIQTGKLLDWLVDRRHCGLRWQAQVSAVRQKIEAALRDMPEHEEIARLLAGAAIHYSHCLRIVDILRGTEASTKNLFGRYSSQRMKDWQEIVALYEKDNTYLAELAALLVRNVTYEVPALRKQIARCQQAQQDLARREEECQLAAAELRERFYASCKQYGITGSNVRQELLALVQDLPSLLSEVGAGVGALSEAVELYQACVEFVCQSSEGPVVPMLRYVGSKGNTTVYEWRTGFEPVKVERPEVQVVPEQPKEDTIDWGDFTLEPIGGGDIDSAAAGGEAQDNEIDWGIVVEPSPQDNGIDWGDGEGNGAQITVLEDGSEEPEAVARGSDALTLLENAATRNQFIDELMELELFLAQRLVEMEEEADVLAASQFQLAPAVLQGQTSTRVGTLLANTRALLDQLSTRRMQHLFIILASPRYVDRVSEMLQQKLNQAELLLAKREALSRKRHEALTEQGVLEPKLDRLQERTRELQQLIEADISKRYGGRPVHLMGVSL", "length": 586, "header": "tr|A0A8V0ZW40-1|A0A8V0ZNV5_CHICK Computationally mapped isoform of CDK5 regulatory subunit associated protein 3 OS=Gallus gallus OX=9031 GN=CDK5RAP3 PE=1 SV=1 CANONICAL=A0A8V0ZNV5-1" }, "locus": { "chromosome": "27", "start_pos": 3696177, "end_pos": 3692315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057808.1", "url": "https://www.ensembl.org/id/ENSGALT00010057808.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035082.1", "url": "https://www.ensembl.org/id/ENSGALP00010035082.1" } ] } }, { "isoform_ac": "A0A8V0ZW44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5/entry#A0A8V0ZW44-1", "sequence": { "sequence": "MWAPRGRGCSEHRDALPEPPAPLCGLRDPGDGVGPHTCCCPAAASPRDYQDVPIDIQTGKLLDWLVDRRHCGLRWQAQVSAVRQKIEAALRDMPEHEEIARLLAGAAIHYSHCLRIVDILRGTEASTKNLFGRYSSQRMKDWQEIVALYEKDNTYLAELAALLVRNVTYEVPALRKQIARCQQAQQDLARREEECQLAAAELRERFYASCKQYGITGSNVRQELLALVQDLPSLLSEVGAGVGALSEAVELYQACVEFVCQSSEGPVVPMLRYVGSKGNTTVYEWRTGFEPVKVERPEVQVVPEQPKEDTIDWGDFTLEPIGGGDIDSAAAGGEAQDNEIDWGIVVEPSPQDNGIDWGDGEGNGAQITVLEDGSEEPEAVARGSDALTLLENAATRNQFIDELMELELFLAQRLVEMEEEADVLAASQFQLAPAVLQGQTSTRVGTLLANTRALLDQLSTRRMQHLFIILASPRYVDRVSEMLQQKLNQAELLLAKREALSRKRHEALTEQGVLEPKLDRLQERTRELQQLIEADISKRYGGRPVHLMGVSL", "length": 552, "header": "tr|A0A8V0ZW44-1|A0A8V0ZNV5_CHICK Computationally mapped isoform of CDK5 regulatory subunit associated protein 3 OS=Gallus gallus OX=9031 GN=CDK5RAP3 PE=1 SV=1 CANONICAL=A0A8V0ZNV5-1" }, "locus": { "chromosome": "27", "start_pos": 3696075, "end_pos": 3692315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057815.1", "url": "https://www.ensembl.org/id/ENSGALT00010057815.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035087.1", "url": "https://www.ensembl.org/id/ENSGALP00010035087.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 14, "go_terms": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "definitive erythrocyte differentiation", "id": "GO:0060318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060318", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "liver development", "id": "GO:0001889", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "cell population proliferation", "id": "GO:0008283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "positive regulation of protein ubiquitination", "id": "GO:0031398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031398", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "negative regulation of protein catabolic process", "id": "GO:0042177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042177", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "apoptotic nuclear changes", "id": "GO:0030262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "positive regulation of protein localization to nucleus", "id": "GO:1900182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "positive regulation of signal transduction by p53 class mediator", "id": "GO:1901798", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901798", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "protein ufmylation", "id": "GO:0071569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071569", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "positive regulation of reticulophagy", "id": "GO:0140501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140501", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "mitogen-activated protein kinase binding", "id": "GO:0051019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051019", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "NF-kappaB binding", "id": "GO:0051059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051059", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "MDM2/MDM4 family protein binding", "id": "GO:0097371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097371", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNV5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNV5" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": 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"synonym", "evidence": [ { "id": "A0A8V0ZNX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "A cytochrome P450 monooxygenase involved in activation of vitamin D precursors. Catalyzes hydroxylation at C-25 of both forms of vitamin D, vitamin D(2) and D(3) (calciol). Can metabolize vitamin D analogs/prodrugs 1alpha-hydroxyvitamin D(2) (doxercalciferol) and 1alpha-hydroxyvitamin D(3) (alfacalcidol) forming 25-hydroxy derivatives. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1#function" }, { "database": "UniProtKB", "id": "ARBA00059364", "url": "https://www.uniprot.org/uniprotkb/ARBA00059364#function" }, { "database": "UniProtKB", "id": "A0A8V1A1N1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N1#function" }, { "database": "UniProtKB", "id": "A0A8V1A1N5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYP2R1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1", "locus": { "chromosome": "5", "start_pos": 10194090, "end_pos": 10203322, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023724", "url": "https://www.ensembl.org/id/ENSGALG00010023724" } ] } } ], "crossref": [ { "id": "A0A8V0ZNX1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423065", "url": "https://www.ncbi.nlm.nih.gov/gene/423065", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RQEMYIG", "url": "https://omabrowser.org/oma/group/RQEMYIG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNX1", "url": "https://www.orthodb.org/?gene=A0A8V0ZNX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZU51", "url": "https://www.orthodb.org/?gene=A0A8V0ZU51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1N1", "url": "https://www.orthodb.org/?gene=A0A8V1A1N1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A1N5", "url": "https://www.orthodb.org/?gene=A0A8V1A1N5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196791", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196791", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-211916", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "32903", "url": "https://www.rhea-db.org/rhea/32903", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46580", "url": "https://www.rhea-db.org/rhea/46580", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46584", "url": "https://www.rhea-db.org/rhea/46584", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "49272", "url": "https://www.rhea-db.org/rhea/49272", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZU51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZU51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1N1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1N5", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A1N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1N5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPAAGDAEPEAAAGGGPWLLLALPPLLLLFALVVRQLLKQRRPPGFPPGPAGLPLIGNIHSLGAEQPHVYMRRQSQIHGQIFSLDLGGISAIVLNGYDAVKECLVHQSEIFADRPSLPLFKKLTNMGGLLNSKYGRGWTEHRKLAVNTFRTFGYGQRSFEHKISEESVFFLDAIDTYKGRPFDLKHLITNAVSNITNLIIFGERFTYEDTEFQHMIEIFSENIELAASASVFLYNAFPWIGILPFGKHQQLFKNAAEVYDFLHKLIERVSENRKSQSPRHFIDAYLDEMDCNKNDPESTYSRENLIFSVGELIIAGTETTTNVLRWAVLFMALYPNIQGHVQKEIDLVIGPNKMPALEEKCKMPYTEAVLHEVLRFCNIVPLGIFHATSKDTVVRGYSIPEGTTVITNLYSVHFDEKYWNNPEVFFPERFLDSNGQFVKKDAFIPFSLGRRHCLGEQLARMELFLFFTSLLQRFHLRFPHGGIPDLKPRLGMTLQPQPYLICAERR", "length": 507, "header": "tr|A0A8V0ZNX1-1|A0A8V0ZNX1_CHICK Isoform 1 of Vitamin D 25-hydroxylase OS=Gallus gallus OX=9031 GN=CYP2R1 PE=3 SV=1 CANONICAL=A0A8V0ZNX1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1/entry#A0A8V0ZNX1-1", "sequence": { "sequence": "MGPAAGDAEPEAAAGGGPWLLLALPPLLLLFALVVRQLLKQRRPPGFPPGPAGLPLIGNIHSLGAEQPHVYMRRQSQIHGQIFSLDLGGISAIVLNGYDAVKECLVHQSEIFADRPSLPLFKKLTNMGGLLNSKYGRGWTEHRKLAVNTFRTFGYGQRSFEHKISEESVFFLDAIDTYKGRPFDLKHLITNAVSNITNLIIFGERFTYEDTEFQHMIEIFSENIELAASASVFLYNAFPWIGILPFGKHQQLFKNAAEVYDFLHKLIERVSENRKSQSPRHFIDAYLDEMDCNKNDPESTYSRENLIFSVGELIIAGTETTTNVLRWAVLFMALYPNIQGHVQKEIDLVIGPNKMPALEEKCKMPYTEAVLHEVLRFCNIVPLGIFHATSKDTVVRGYSIPEGTTVITNLYSVHFDEKYWNNPEVFFPERFLDSNGQFVKKDAFIPFSLGRRHCLGEQLARMELFLFFTSLLQRFHLRFPHGGIPDLKPRLGMTLQPQPYLICAERR", "length": 507, "header": "tr|A0A8V0ZNX1-1|A0A8V0ZNX1_CHICK Isoform 1 of Vitamin D 25-hydroxylase OS=Gallus gallus OX=9031 GN=CYP2R1 PE=3 SV=1 CANONICAL=A0A8V0ZNX1-1" }, "locus": { "chromosome": "5", "start_pos": 10202706, "end_pos": 10194664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057843.1", "url": "https://www.ensembl.org/id/ENSGALT00010057843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035104.1", "url": "https://www.ensembl.org/id/ENSGALP00010035104.1" } ] } }, { "isoform_ac": "A0A8V0ZU51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1/entry#A0A8V0ZU51-1", "sequence": { "sequence": "MGPAAGDAEPEAAAGGGPWLLLALPPLLLLFALVVRQLLKQRRPPGFPPGPAGLPLIGNIHSLGAEQPHVYMRRQSQIHGQIFSLDLGGISAIVLNGYDAVKECLVHQSEIFADRPSLPLFKKLTNMGGLLNSKYGRGWTEHRKLAVNTFRTFGYGQRSFEHKISEESVFFLDAIDTYKGRPFDLKHLITNAVSNITNLIIFGERFTYEDTEFQHMIEIFSENIELAASASVFLYNAFPWIGILPFGKHQQLFKNAAEVYDFLHKLIERVSENRKSQSPRHFIDAYLDEMDCNKNDPESTYSRENLIFSVGELIIAGTETTTNVLRWAVLFMALYPNIQGRRHCLGEQLARMELFLFFTSLLQRFHLRFPHGGIPDLKPRLGMTLQPQPYLICAERR", "length": 397, "header": "tr|A0A8V0ZU51-1|A0A8V0ZNX1_CHICK Computationally mapped isoform of Vitamin D 25-hydroxylase OS=Gallus gallus OX=9031 GN=CYP2R1 PE=3 SV=1 CANONICAL=A0A8V0ZNX1-1" }, "locus": { "chromosome": "5", "start_pos": 10202706, "end_pos": 10194664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057838.1", "url": "https://www.ensembl.org/id/ENSGALT00010057838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035101.1", "url": "https://www.ensembl.org/id/ENSGALP00010035101.1" } ] } }, { "isoform_ac": "A0A8V1A1N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1/entry#A0A8V1A1N1-1", "sequence": { "sequence": "MGGLLNSKYGRGWTEHRKLAVNTFRTFGYGQRSFEHKISEESVFFLDAIDTYKGRPFDLKHLITNAVSNITNLIIFGERFTYEDTEFQHMIEIFSENIELAASASVFLYNAFPWIGILPFGKHQQLFKNAAEVYDFLHKLIERVSENRKSQSPRHFIDAYLDEMDCNKNDPESTYSRENLIFSVGELIIAGTETTTNVLRWAVLFMALYPNIQGHVQKEIDLVIGPNKMPALEEKCKMPYTEAVLHEVLRFCNIVPLGIFHATSKDTVVRGYSIPEGTTVITNLYSVHFDEKYWNNPEVFFPERFLDSNGQFVKKDAFIPFSLGRRHCLGEQLARMELFLFFTSLLQRFHLRFPHGGIPDLKPRLGMTLQPQPYLICAERR", "length": 381, "header": "tr|A0A8V1A1N1-1|A0A8V0ZNX1_CHICK Computationally mapped isoform of Vitamin D 25-hydroxylase OS=Gallus gallus OX=9031 GN=CYP2R1 PE=3 SV=1 CANONICAL=A0A8V0ZNX1-1" }, "locus": { "chromosome": "5", "start_pos": 10199971, "end_pos": 10194664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057835.1", "url": "https://www.ensembl.org/id/ENSGALT00010057835.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035100.1", "url": "https://www.ensembl.org/id/ENSGALP00010035100.1" } ] } }, { "isoform_ac": "A0A8V1A1N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1/entry#A0A8V1A1N5-1", "sequence": { "sequence": "MSSSRHQVPAGSAPTVPTAHQRSPIGRAHSLSRGQKGGGEKKETRQGCLLAVSQTREGCRKDIPKNRPSLPLFKKLTNMGGLLNSKYGRGWTEHRKLAVNTFRTFGYGQRSFEHKISEESVFFLDAIDTYKGRPFDLKHLITNAVSNITNLIIFGERFTYEDTEFQHMIEIFSENIELAASASVFLYNAFPWIGILPFGKHQQLFKNAAEVYDFLHKLIERVSENRKSQSPRHFIDAYLDEMDCNKNDPESTYSRENLIFSVGELIIAGTETTTNVLRWAVLFMALYPNIQGHVQKEIDLVIGPNKMPALEEKCKMPYTEAVLHEVLRFCNIVPLGIFHATSKDTVVRGYSIPEGTTVITNLYSVHFDEKYWNNPEVFFPERFLDSNGQFVKKDAFIPFSLGRRHCLGEQLARMELFLFFTSLLQRFHLRFPHGGIPDLKPRLGMTLQPQPYLICAERR", "length": 459, "header": "tr|A0A8V1A1N5-1|A0A8V0ZNX1_CHICK Computationally mapped isoform of Vitamin D 25-hydroxylase OS=Gallus gallus OX=9031 GN=CYP2R1 PE=3 SV=1 CANONICAL=A0A8V0ZNX1-1" }, "locus": { "chromosome": "5", "start_pos": 10203123, "end_pos": 10194664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057845.1", "url": "https://www.ensembl.org/id/ENSGALT00010057845.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035105.1", "url": "https://www.ensembl.org/id/ENSGALP00010035105.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-196791", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196791", "resource": "Reactome", "description": "Vitamin D (calciferol) metabolism" }, { "id": "R-GGA-211916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211916", "resource": "Reactome", "description": "Vitamins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ABJ2-1", "protein_name": "Vitamin D 25-hydroxylase", "gene_name": "CYP2R1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWEPPGAEVFPAALGGVLFLLLFLGVRQLLKQRRPSGFPPGPSGLPFIGNIYSLAASAELPHIYMKKQSQVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRSFGYGQKSFESKILEETKFFMDAIETYSSRPFDFKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGILPFGKHQQLFRNAAVVYDFLSRLIEKASINRKPQSPQHFVDAYLDEMDQGEKDPSSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVHKEIDLIIGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAIVRGYSIPKGTTVITNLYSVHFDEKYWRDPEIFYPERFLDSSGCFSKKEALVPFSLGRRHCLGEQLARMEMFLFFTALLQRFHLHFPHGLVPNLKPKLGMTLQPQPYLICAERR", "length": 500 }, "evidence": [ { "id": "A0A8V0ZNX1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNX1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6P2A1-1", "protein_name": "Vitamin D 25-hydroxylase", "gene_name": "cyp2r1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MISIKRLTSPLSLSWEQTLICLLGLFTTLLILLVIRQLVKQRRPRGFPPGPTPLPIIGNMLSLATEPHVYMKRQSDIHGQIFSLDLGGIPTVILNGYDAIKECLYHQSEVFADRPSLPLFQKMTKMGGLLNCKYGRGWIEHHKLAVNCFRYFGTGQRMFERISEECLYFLDAIDQHQGKPFNPKHLVTNAVSNITNLIIFGQRFTYDDGDFQHMIEIFSENVELAASSWAFLYNAFPWMEYLPFGKHQRLFRNANEVYKFLLQIIRRFSQGRVPQSPQHYIDAYLDEMEQSTPDKATSFSQDNLIFSVGELIIAGTETTTNCLRWAMLYMALYPRIQEKVQMEIDSVLNGRQPAFEDRQRMPYVEAVLHEVLRLCNIVPLGIFRATSQDAVVRGYTIPKGTMVITNLYSVHFDEKYWSDPSIFCPERFLDCNGKFIRHEAFLPFSIGKRHCLGEQLARLEMFLFFTTLLQRFHLQFSEGFIPSLSAKLGMTLQPQPYSICAIRRQQ", "length": 506 }, "evidence": [ { "id": "A0A8V0ZNX1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNX1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q42600-1", "protein_name": "Cytochrome P450 84A1", "gene_name": "CYP84A1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MESSISQTLSKLSDPTTSLVIVVSLFIFISFITRRRRPPYPPGPRGWPIIGNMLMMDQLTHRGLANLAKKYGGLCHLRMGFLHMYAVSSPEVARQVLQVQDSVFSNRPATIAISYLTYDRADMAFAHYGPFWRQMRKVCVMKVFSRKRAESWASVRDEVDKMVRSVSCNVGKPINVGEQIFALTRNITYRAAFGSACEKGQDEFIRILQEFSKLFGAFNVADFIPYFGWIDPQGINKRLVKARNDLDGFIDDIIDEHMKKKENQNAVDDGDVVDTDMVDDLLAFYSEEAKLVSETADLQNSIKLTRDNIKAIIMDVMFGGTETVASAIEWALTELLRSPEDLKRVQQELAEVVGLDRRVEESDIEKLTYLKCTLKETLRMHPPIPLLLHETAEDTSIDGFFIPKKSRVMINAFAIGRDPTSWTDPDTFRPSRFLEPGVPDFKGSNFEFIPFGSGRRSCPGMQLGLYALDLAVAHILHCFTWKLPDGMKPSELDMNDVFGLTAPKATRLFAVPTTRLICAL", "length": 520 }, "evidence": [ { "id": "A0A8V0ZNX1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNX1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54SV9-1", "protein_name": "Probable cytochrome P450 515B1", "gene_name": "cyp515B1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATLLLVIIFMITFIIYKNFDSKRKNKYPPGPINLPFIGGLYKLKPGKQHLSLNELYQKYGKVFSMKFGSYDTVILNEPDVIVEAFHLNSTSFMDRILLPSFEVVGKNQNIGFTQTEYWKKIRGILNISLTKSKTRLLEGLFNQEYFRFDQFIKKQLKSKSDTMFIRPYLKRLSFNIIYSYLFSETIPYEDELIPSDILDFIHASEELLVVLSRMPSDYIKVLRPFESHKKLKEICDRMSKFIKPRVDKKVELLDQDNPKCFIDYLILQIRSDPSQTIKIDAIQYIVLDLLVGGTDSTSSALEWMILFLSNHESIQEKLYNEICKNTNTNTTATTTENDNESYFPKLIEKNNYPLFNACVKETLRRSPPVPLGLPHLCSEDTEIGGYLIPKGTQIISNIYSASNCDKVFTDPLEFNPLRFIENSPPQTVTFSTGPRVCPGKNLSEDELFSFGTKLFKTFKFSRPNKNQLYDEVAILGITLEPKPFITKVSLRS", "length": 493 }, "evidence": [ { "id": "A0A8V0ZNX1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNX1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6VVW9-1", "protein_name": "Vitamin D 25-hydroxylase", "gene_name": "Cyp2r1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLELPGARACAGALAGALLLLLFVLVVRQLLRQRRPAGFPPGPPRLPFVGNICSLALSADLPHVYMRKQSRVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWIDHRRLAVNSFHYFGSGQKSFESKILEETWSLIDAIETYKGGPFDLKQLITNAVSNITNLILFGERFTYEDTDFQHMIELFSENVELAASAPVFLYNAFPWIGILPFGKHQRLFRNADVVYDFLSRLIEKAAVNRKPHLPHHFVDAYLDEMDQGQNDPLSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVHKEIDLIVGHNRRPSWEYKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWKDPDMFYPERFLDSNGYFTKKEALIPFSLGRRHCLGEQLARMEMFLFFTSLLQQFHLHFPHELVPNLKPRLGMTLQPQPYLICAERR", "length": 501 }, "evidence": [ { "id": "A0A8V0ZNX1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNX1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6VVX0-1", "protein_name": "Vitamin D 25-hydroxylase", "gene_name": "CYP2R1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWKLWRAEEGAAALGGALFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSELPHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGILPFGKHQQLFRNAAVVYDFLSRLIEKASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHELVPDLKPRLGMTLQPQPYLICAERR", "length": 501 }, "evidence": [ { "id": "A0A8V0ZNX1", "url": "https://omabrowser.org/oma/group/A0A8V0ZNX1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "vitamin D metabolic process", "id": "GO:0042359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042359", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" }, { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" }, { "name": "organic acid metabolic process", "id": "GO:0006082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" }, { "name": "vitamin D3 25-hydroxylase activity", "id": "GO:0030343", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030343", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" }, { "name": "D3 vitamins binding", "id": "GO:1902271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "id": "GO:0016705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016705", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "32903", "name": "", "equation": "calciol + reduced [NADPH--hemoprotein reductase] + O2 = calcidiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNX1-1" ], "evidence": [ { "id": "32903", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32903" } ] }, { "id": "46580", "name": "", "equation": "vitamin D2 + reduced [NADPH--hemoprotein reductase] + O2 = 25-hydroxyvitamin D2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNX1-1" ], "evidence": [ { "id": "46580", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46580" } ] }, { "id": "46584", "name": "", "equation": "1alpha-hydroxyvitamin D2 + reduced [NADPH--hemoprotein reductase] + O2 = 1alpha,25-dihydroxyvitamin D2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNX1-1" ], "evidence": [ { "id": "46584", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46584" } ] }, { "id": "49272", "name": "", "equation": "alfacalcidol + reduced [NADPH--hemoprotein reductase] + O2 = calcitriol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZNX1-1" ], "evidence": [ { "id": "49272", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/49272" } ] }, { "id": "R-GGA-209845", "name": "CYP2R1 25-hydroxylates VD3 to 25(OH)D", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [ "R-ALL-8963870" ], "output_participant_list": [ "R-ALL-8963879" ], "enzyme_list": [ "A0A8V0ZNX1-1" ], "evidence": [ { "id": "R-GGA-209845", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-209845" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-8963870", "participant_name": "VD3 [endoplasmic reticulum membrane]", "crossref": [ { "id": "28940", "database": "ChEBI", "url": "" }, { "id": "C05443", "database": "COMPOUND", "url": "" }, { "id": "ZINC000004474460", "database": "ZINC", "url": "" }, { "id": "HMDB0000876", "database": "HMDB Metabolite", "url": "" } ] }, { "participant_id": "R-ALL-8963879", "participant_name": "25(OH)D [endoplasmic reticulum membrane]", "crossref": [ { "id": "C01561", "database": "COMPOUND", "url": "" }, { "id": "ZINC000004474414", "database": "ZINC", "url": "" }, { "id": "HMDB0003550", "database": "HMDB Metabolite", "url": "" }, { "id": "6921", "database": "Guide to Pharmacology - Ligands", "url": "" }, { "id": "17933", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0ZNX1", "gene_name": "CYP2R1", "activity": [ { "ec_number": "1.14.14.24", "activity": "calciol + reduced [NADPH--hemoprotein reductase] + O2 = calcidiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+).", "evidence": [ { "id": "A0A8V0ZNX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ] }, { "ec_number": "1.14.14.24", "activity": "", "evidence": [ { "id": "A0A8V0ZNX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNX1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.14.24", "ec_name": "calciol + reduced [NADPH--hemoprotein reductase] + O2 = calcidiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+).", "evidence": [ { "id": "1.14.14.24", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.14.24" }, { "id": "1.14.14.24", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.14.24" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNZ1-1", "uniprot_ac": "A0A8V0ZNZ1", "uniprot_id": "A0A8V0ZNZ1_CHICK", "mass": { "chemical_mass": 122724.0, "monoisotopic_mass": 122724.0 }, "refseq": { "ac": "XP_004945204", "name": "ras-associating and dilute domain-containing protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945204" }, "gene_names": [ { "name": "RADIL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1" } ] }, { "name": "RADIL", "type": "synonym", "evidence": [ { "id": "XP_004945204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945204" } ] } ], "protein_names": [ { "name": "Ras-associating and dilute domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1/entry#names_and_taxonomy" } ] }, { "name": "ras-associating and dilute domain-containing protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_004945204", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945204" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004945204.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004945204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945204" } ] }, { "annotation": "Downstream effector of Rap required for cell adhesion and migration of neural crest precursors during development.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1#function" }, { "database": "UniProtKB", "id": "ARBA00057550", "url": "https://www.uniprot.org/uniprotkb/ARBA00057550#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RADIL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1", "locus": { "chromosome": "14", "start_pos": 4021988, "end_pos": 4041085, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021155", "url": "https://www.ensembl.org/id/ENSGALG00010021155" } ] } } ], "crossref": [ { "id": "A0A8V0ZNZ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06690", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06690", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15472", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15472", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22733", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22733", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416479", "url": "https://www.ncbi.nlm.nih.gov/gene/416479", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNZ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZNZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16027:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16027:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004945204", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004945204", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZNZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGQRGREKDGKLLPVTTSHAMFYGSSSTMAPPSKSRLKRQSRLFSQVLYRTLSYKDRSSTSAFPDGDDPAELSTQLSAPGILKIFGGNICAGTNYKSVLATGSSGALELVKEALERYGLSQLNAGQYALCDVIGRFEGPEKRWQTEGLRVLGDHEKPLLIQDLWKPREGFSRRLELRRRAEVEEMAARDVDTTTAGINAQARKLQRHRARGAMRVLAGAKRLGTPPALRRSLSESSLGRPRDEELRRHCPALRGPEERSGSSMRYSLYHSPHLLLLQGYSQQHDSLVYLLNREQHTVGQRTQASKPSISLSAPDILPLHCTIRRLRASWHRSEEKLVLEPIAGASVSVNFSAVTRTVVLRHGDLLSLGLYYLLLYKDPMKAQPLPAQTLLRLRALHPEGPSVCGTCGSLLKEQGGPNANRQSPEPTDGPRAPRRRLQLEFEPEAEDVLLRRIMTLIEPGGDDHKLTPAFLLCLCIQHSATSFQPGDFGQLLLKAAKMIQRTVWERTRELAEKQSQHQDPAALSCFTIADLLPDLQHILFWMSNAIEVLYFVQQKSPTYIQSMEEEMDVKGSKESLFSSTITASEEAMTVLEEVIMYTFQQCVYYISKCLYVSLPALLECNPFQNESREGWRAAPPLPEELCRVVLIYQAALDLLRQYEVHPEITSQMFAYLFFFSNTLLFNQLLDKGSSLGCFHWSQGVKLRASVRLLLEWLRGAGFEQLSQQFFAKLASVANLLAMPGSQLLQMTWPSLRAEFPVLSPAQLHRVLSHCQAAMEVGSVAAWQPWDEESTAAFQPDAVLESFDNHPPIVLPSSGFKVDLEVETLDDNIYRHLLYIRHFLWSLQSKSPHGSEGPCSAPPKSEPPIVPEVLEVSPSPVMTPGSTVPPSGRCTPGGCTDLEADEPPPLTSTTNGCPRQHPTGEQQLQEKLQQLQLGRGPPPPAPSCLLTPPTTPLNFDSAGPESPQGTTKGLQDPRRNGISSTKGGSPEGCSPTPYDFPTPESSSRSSATDDFCYVFVVELERGALGLGMGLIDGLHTPLGSPGIYIRTLIEGSPAAADGRLAIGDRILAVNGTSLIGADYQSAVDLIRSGGKKLRFLVAKSDMEIAKKIISSSASS", 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"MEGQRGREKDGKLLPVTTSHAMFYGSSSTMAPPSKSRLKRQSRLFSQVLYRTLSYKDRSSTSAFPDGDDPAELSTQLSAPGILKIFGGNICAGTNYKSVLATGSSGALELVKEALERYGLSQLNAGQYALCDVIGRFEGPEKRWQTEGLRVLGDHEKPLLIQDLWKPREGFSRRLELRRRAEVEEMAARDVDTTTAGINAQARKLQRHRARGAMRVLAGAKRLGTPPALRRSLSESSLGRPRDEELRRHCPALRGPEERSGSSMRYSLYHSPHLLLLQGYSQQHDSLVYLLNREQHTVGQRTQASKPSISLSAPDILPLHCTIRRLRASWHRSEEKLVLEPIAGASVSVNFSAVTRTVVLRHGDLLSLGLYYLLLYKDPMKAQPLPAQTLLRLRALHPEGPSVCGTCGSLLKEQGGPNANRQSPEPTDGPRAPRRRLQLEFEPEAEDVLLRRIMTLIEPGGDDHKLTPAFLLCLCIQHSATSFQPGDFGQLLLKAAKMIQRTVWERTRELAEKQSQHQDPAALSCFTIADLLPDLQHILFWMSNAIEVLYFVQQKSPTYIQSMEEEMDVKGSKESLFSSTITASEEAMTVLEEVIMYTFQQCVYYISKCLYVSLPALLECNPFQNESREGWRAAPPLPEELCRVVLIYQAALDLLRQYEVHPEITSQMFAYLFFFSNTLLFNQLLDKGSSLGCFHWSQGVKLRASVRLLLEWLRGAGFEQLSQQFFAKLASVANLLAMPGSQLLQMTWPSLRAEFPVLSPAQLHRVLSHCQAAMEVGSVAAWQPWDEESTAAFQPDAVLESFDNHPPIVLPSSGFKVDLEVETLDDNIYRHLLYIRHFLWSLQSKSPHGSEGPCSAPPKSEPPIVPEVLEVSPSPVMTPGSTVPPSGRCTPGGCTDLEADEPPPLTSTTNGCPRQHPTGEQQLQEKLQQLQLGRGPPPPAPSCLLTPPTTPLNFDSAGPESPQGTTKGLQDPRRNGISSTKGGSPEGCSPTPYDFPTPESSSRSSATDDFCYVFVVELERGALGLGMGLIDGLHTPLGSPGIYIRTLIEGSPAAADGRLAIGDRILAVNGTSLIGADYQSAVDLIRSGGKKLRFLVAKSDMEIAKKIISSSASS", "length": 1114, "header": "tr|A0A8V0ZNZ1-1|A0A8V0ZNZ1_CHICK Isoform 1 of Ras-associating and dilute domain-containing protein OS=Gallus gallus OX=9031 GN=RADIL PE=3 SV=1 CANONICAL=A0A8V0ZNZ1-1" }, "locus": { "chromosome": "14", "start_pos": 4037272, "end_pos": 4024087, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051233.1", "url": "https://www.ensembl.org/id/ENSGALT00010051233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030424.1", "url": "https://www.ensembl.org/id/ENSGALP00010030424.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 427, "start_aa": "Thr", "end_pos": 427, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr427", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1" } ], "pmid": "" }, { "name": "neural crest cell migration", "id": "GO:0001755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001755", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": 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"count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZNZ3-1", "uniprot_ac": "A0A8V0ZNZ3", "uniprot_id": "A0A8V0ZNZ3_CHICK", "mass": { "chemical_mass": 26204.0, "monoisotopic_mass": 26204.0 }, "refseq": {}, "gene_names": [ { "name": "SAMD10", "type": "recommended", "evidence": [ { "id": "A0A8V0ZNZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ3" } ] } ], "protein_names": [ { "name": "Sterile alpha motif domain containing 10", "type": "synonym", "evidence": [ { "id": "A0A8V0ZNZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZNZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SAMD10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ3", "locus": { "chromosome": "20", "start_pos": 9794432, "end_pos": 9787365, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022560", "url": "https://www.ensembl.org/id/ENSGALG00010022560" } ] } } ], "crossref": [ { "id": "A0A8V0ZNZ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZNZ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09510", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09510", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052268", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052268", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZNZ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZNZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": 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"MRGGRDGAALVTAGAVRALARIPPPAGMHQGRPSLCCVASIRGSQGAPEPAAAAAAHFSFCRSLLEHTVSAENLSYRLQRSPGTSLTWHDGRSQRGEGSRAIKLLRQPGTEGSQSRGCDHYGIYHTSPTLGSLTKPVVLWSQQDVCKWLKKHCPHNYLIYVEAFSHHAITGRALLRLNGEKLQRMGIAHEAQRQEVLQQVLQLQVREEVRNLQLLSQDCTNTVNRAALGWTVHRRPET", "length": 238, "header": "tr|A0A8V0ZNZ3-1|A0A8V0ZNZ3_CHICK Isoform 1 of Sterile alpha motif domain containing 10 OS=Gallus gallus OX=9031 GN=SAMD10 PE=4 SV=1 CANONICAL=A0A8V0ZNZ3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZNZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNZ3/entry#A0A8V0ZNZ3-1", "sequence": { "sequence": "MRGGRDGAALVTAGAVRALARIPPPAGMHQGRPSLCCVASIRGSQGAPEPAAAAAAHFSFCRSLLEHTVSAENLSYRLQRSPGTSLTWHDGRSQRGEGSRAIKLLRQPGTEGSQSRGCDHYGIYHTSPTLGSLTKPVVLWSQQDVCKWLKKHCPHNYLIYVEAFSHHAITGRALLRLNGEKLQRMGIAHEAQRQEVLQQVLQLQVREEVRNLQLLSQDCTNTVNRAALGWTVHRRPET", "length": 238, "header": "tr|A0A8V0ZNZ3-1|A0A8V0ZNZ3_CHICK Isoform 1 of Sterile alpha motif domain containing 10 OS=Gallus gallus OX=9031 GN=SAMD10 PE=4 SV=1 CANONICAL=A0A8V0ZNZ3-1" }, 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}, { "id": "PF02022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06817", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06817", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "DVMIEFRNIHQTLNTEGVMIAPEKVQLSAPRKYLGWTLTNTIVTPQKLQLNTKIETLHDAQRFLGDLKWLSPVVGIPNELLESLRPLLRGTDPAQPVTVTMQHKRLLQQIMDCIIHGSVRRRDPDLPIQVMVWYGPKYLLGALAQSKKKTGEVWVLEWICPSLQRSKTLLQKTELLAEVIKKGRERTLQITGMEPVCVQLPMQKDTLTWYVQHSPELQDALLRAGSTVSMEKIPNVPLHWIGQRSWLRIPKQHETPLQNAITAYTDTGWKSRTTAVTWQQGGSWRHHLIAADDKDLLQTLELVAVVWAMMNLIGPLNVVTDSLYVAGVCHRIEEAYIKEVQNRRLYELFVQLQRAIRIREHSYAVIHVRGHKWEIDLGEGNARADRLVSLAQRPLVSQHVLAREAHSMFHQNAKGLRREYQITYEDAKAIVRSCPVCSHLNGGMGLGLGVNPRGLKANENRQMNVTHVGEFGQLKYVHVSIGTYSHFMWATAQPGEKAMYVERHLRCCFAVMGISLQIKTDNGPAYTSRRLGEFLQTWGVKHSTGIPNSPTGQAIVEQGNCGWTADPVRSCFSPPGSVQVKQLLRITVSHRTMMGVGERNAEL", "length": 603, "header": "tr|A0A8V0ZP17-1|A0A8V0ZP17_CHICK Isoform 1 of RNA-directed DNA polymerase OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZP17-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17/entry#A0A8V0ZP17-1", "sequence": { "sequence": "DVMIEFRNIHQTLNTEGVMIAPEKVQLSAPRKYLGWTLTNTIVTPQKLQLNTKIETLHDAQRFLGDLKWLSPVVGIPNELLESLRPLLRGTDPAQPVTVTMQHKRLLQQIMDCIIHGSVRRRDPDLPIQVMVWYGPKYLLGALAQSKKKTGEVWVLEWICPSLQRSKTLLQKTELLAEVIKKGRERTLQITGMEPVCVQLPMQKDTLTWYVQHSPELQDALLRAGSTVSMEKIPNVPLHWIGQRSWLRIPKQHETPLQNAITAYTDTGWKSRTTAVTWQQGGSWRHHLIAADDKDLLQTLELVAVVWAMMNLIGPLNVVTDSLYVAGVCHRIEEAYIKEVQNRRLYELFVQLQRAIRIREHSYAVIHVRGHKWEIDLGEGNARADRLVSLAQRPLVSQHVLAREAHSMFHQNAKGLRREYQITYEDAKAIVRSCPVCSHLNGGMGLGLGVNPRGLKANENRQMNVTHVGEFGQLKYVHVSIGTYSHFMWATAQPGEKAMYVERHLRCCFAVMGISLQIKTDNGPAYTSRRLGEFLQTWGVKHSTGIPNSPTGQAIVEQGNCGWTADPVRSCFSPPGSVQVKQLLRITVSHRTMMGVGERNAEL", "length": 603, "header": "tr|A0A8V0ZP17-1|A0A8V0ZP17_CHICK Isoform 1 of RNA-directed DNA polymerase OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZP17-1" }, "locus": { "chromosome": "1", "start_pos": 78234216, "end_pos": 78231991, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058067.1", "url": "https://www.ensembl.org/id/ENSGALT00010058067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035245.1", "url": "https://www.ensembl.org/id/ENSGALP00010035245.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17" } ], "pmid": "" }, { "name": "RNA stem-loop binding", "id": "GO:0035613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035613", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZP17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 448, "end_pos": 560, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZP17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17" }, { "id": "PS50876", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50876" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase-type", "eco_id": "ECO_0000259", "start_pos": 397, "end_pos": 438, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZP17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP17" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 257, "end_pos": 393, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.7.49", "ec_name": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "2.7.7.49", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 464, "end_pos": 466 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZP35-1", "uniprot_ac": "A0A8V0ZP35", "uniprot_id": "A0A8V0ZP35_CHICK", "mass": { "chemical_mass": 40567.0, "monoisotopic_mass": 40567.0 }, "refseq": {}, "gene_names": [ { "name": "LRRC46", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP35" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 46", "type": "synonym", "evidence": [ { "id": "A0A8V0ZP35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP35/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC46", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP35", "locus": { "chromosome": "27", "start_pos": 3724720, "end_pos": 3728680, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023784", "url": "https://www.ensembl.org/id/ENSGALG00010023784" } ] } } ], "crossref": [ { "id": "A0A8V0ZP35", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP35", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP35", "url": "https://www.orthodb.org/?gene=A0A8V0ZP35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45973", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45973", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45973:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45973:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZP35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAPALPHIPLSTQHKDPGRGQGPCPPAPTVAGEEEALPGGREQQSLGVTLTDRLMAARSLPGLGETMCPVSCSEELPALQTIRLDREDICTIGRLGSLLGIHSLYLQRNRIEKIENLDCFPNLQFLCLAGNCIRKVENLRPLQHLRFLDLSQNQIQTLDADELPRSLRLLDLTGNECTHQPGYRELVLGALPHLLQLDAQPLHSCVDPAPDEKQEEKHCSSSEDSDDESFSEPSAPFTTGKGSQTEAAHAACLGVSLSPGVTQAARSSDFFTDLQQALAGRSRRRQGKALEEHQARLQELQEHGGLLLPPLPLFSLGTESCLPSSPGTTTAPCPGRSELRPQAKPGRSQQPEAAAILSQPRPTALQGEPCSKGAGK", "length": 377, "header": "tr|A0A8V0ZP35-1|A0A8V0ZP35_CHICK Isoform 1 of Leucine rich repeat containing 46 OS=Gallus gallus OX=9031 GN=LRRC46 PE=4 SV=1 CANONICAL=A0A8V0ZP35-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP35/entry#A0A8V0ZP35-1", "sequence": { "sequence": "MSAPALPHIPLSTQHKDPGRGQGPCPPAPTVAGEEEALPGGREQQSLGVTLTDRLMAARSLPGLGETMCPVSCSEELPALQTIRLDREDICTIGRLGSLLGIHSLYLQRNRIEKIENLDCFPNLQFLCLAGNCIRKVENLRPLQHLRFLDLSQNQIQTLDADELPRSLRLLDLTGNECTHQPGYRELVLGALPHLLQLDAQPLHSCVDPAPDEKQEEKHCSSSEDSDDESFSEPSAPFTTGKGSQTEAAHAACLGVSLSPGVTQAARSSDFFTDLQQALAGRSRRRQGKALEEHQARLQELQEHGGLLLPPLPLFSLGTESCLPSSPGTTTAPCPGRSELRPQAKPGRSQQPEAAAILSQPRPTALQGEPCSKGAGK", "length": 377, "header": "tr|A0A8V0ZP35-1|A0A8V0ZP35_CHICK Isoform 1 of Leucine rich repeat containing 46 OS=Gallus gallus OX=9031 GN=LRRC46 PE=4 SV=1 CANONICAL=A0A8V0ZP35-1" }, "locus": { "chromosome": "27", "start_pos": 3728468, "end_pos": 3725724, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010057981.1", "url": "https://www.ensembl.org/id/ENSGALT00010057981.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035170.1", "url": "https://www.ensembl.org/id/ENSGALP00010035170.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 30, "start_aa": "Thr", "end_pos": 30, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr30", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP35" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, 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"tr|A0A8V0ZP47-1|A0A8V0ZP47_CHICK Isoform 1 of Leucine rich melanocyte differentiation associated OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZP47-1" }, "locus": { "chromosome": "6", "start_pos": 14964543, "end_pos": 14953791, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054056.1", "url": "https://www.ensembl.org/id/ENSGALT00010054056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032587.1", "url": "https://www.ensembl.org/id/ENSGALP00010032587.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP47" } ], "pmid": "" } ] } ] }, 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2", "type": "synonym", "evidence": [ { "id": "XP_015141770", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141770" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141770", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141770" } ] }, { "annotation": "Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. 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] } } ], "crossref": [ { "id": "A0A8V0ZP51", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP51", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01210", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01210", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09540", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09540", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11764", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11764", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "770081", "url": "https://www.ncbi.nlm.nih.gov/gene/770081", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": 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"MSLKGSLSSSPGSTNGSMGKADGASKLSGKDLYEQRKKYSNSNIIMHETSQYHVQHLATFIMDKSESIVTVDDAIRKLLLLNSKEKIWTQEMLLQVNDKSIRLLDCESQEELEDFPLPTVQHCQTVLNQMRYSSILLLVCQDSEQHKPDIHFFNCDEVEAEMVHEDIESALADHKHGKKIRPQTLKANQEKIKQRQSILPPPQGPAPIPFQHDMRGQAMNRNRVAPPAQYEPDYERRGSASQDHEESRAILAQKIEKETQILNCTLDDIEVFVARLQKAAEAFKQLNQRKKGKKNKKKGPAEGMLTLRARPPSEAEFIDCFQKTKLAFNLLAKLRKHIQNPSASELVHFLFGPLELIVSSCGGPELARSVISPLLSKDATDFLRGHLTPKEISLWDSLGEAWTRSRAEWPREANIPTYIPKFRNGWEPPIEIFRGAPWEIDIGHLQEELSSANGYPYRNSSLKRGQAADQTQAVDAFKQNVTQHVNRNFEAQAMAQPKRYAKIRYDFTARNANELSVLKDEILEVLEDNKQWWKLLNRSGQAGYVPYNILDVVKLEELEQANQRYKGDPSPRGYGPSSPTHKLPASYAGDKWGSEMLSRNSPQDAKEQLLHQMDEVNDELLKKITNSKIQPPQRNFRVEKPQEVFVPLTFESSAEEVKAWLEAKSFSKGTVEHLGILTGAQLFSLNREELKKVCGDEGNRVYSKITVEKNQLEKNRGETELQEIMKRRQERIDSAN", "length": 736, "header": "tr|A0A8V0ZP51-1|A0A8V0ZP51_CHICK Isoform 1 of Epidermal growth factor receptor kinase substrate 8-like protein 2 OS=Gallus gallus OX=9031 GN=EPS8L2 PE=1 SV=1 CANONICAL=A0A8V0ZP51-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51/entry#A0A8V0ZP51-1", "sequence": { "sequence": "MSLKGSLSSSPGSTNGSMGKADGASKLSGKDLYEQRKKYSNSNIIMHETSQYHVQHLATFIMDKSESIVTVDDAIRKLLLLNSKEKIWTQEMLLQVNDKSIRLLDCESQEELEDFPLPTVQHCQTVLNQMRYSSILLLVCQDSEQHKPDIHFFNCDEVEAEMVHEDIESALADHKHGKKIRPQTLKANQEKIKQRQSILPPPQGPAPIPFQHDMRGQAMNRNRVAPPAQYEPDYERRGSASQDHEESRAILAQKIEKETQILNCTLDDIEVFVARLQKAAEAFKQLNQRKKGKKNKKKGPAEGMLTLRARPPSEAEFIDCFQKTKLAFNLLAKLRKHIQNPSASELVHFLFGPLELIVSSCGGPELARSVISPLLSKDATDFLRGHLTPKEISLWDSLGEAWTRSRAEWPREANIPTYIPKFRNGWEPPIEIFRGAPWEIDIGHLQEELSSANGYPYRNSSLKRGQAADQTQAVDAFKQNVTQHVNRNFEAQAMAQPKRYAKIRYDFTARNANELSVLKDEILEVLEDNKQWWKLLNRSGQAGYVPYNILDVVKLEELEQANQRYKGDPSPRGYGPSSPTHKLPASYAGDKWGSEMLSRNSPQDAKEQLLHQMDEVNDELLKKITNSKIQPPQRNFRVEKPQEVFVPLTFESSAEEVKAWLEAKSFSKGTVEHLGILTGAQLFSLNREELKKVCGDEGNRVYSKITVEKNQLEKNRGETELQEIMKRRQERIDSAN", "length": 736, "header": "tr|A0A8V0ZP51-1|A0A8V0ZP51_CHICK Isoform 1 of Epidermal growth factor receptor kinase substrate 8-like protein 2 OS=Gallus gallus OX=9031 GN=EPS8L2 PE=1 SV=1 CANONICAL=A0A8V0ZP51-1" }, "locus": { "chromosome": "5", "start_pos": 704286, "end_pos": 678876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053907.1", "url": "https://www.ensembl.org/id/ENSGALT00010053907.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032461.1", "url": "https://www.ensembl.org/id/ENSGALP00010032461.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:770081", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:770081", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q99K30-1", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "gene_name": "Eps8l2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQSASMSCCPGAANGSLGRSDGVPRMSAKDLFEQRKKYSNSNVIMHETSQYHVQHLATFIMDKSEAIASVDDAIRKLVQLSSKEKVWAQEVLLQVNDKSLRLLDVESQEELENFPLPTVQHSQTVLNQLRYPSVLLLVCQDSDQNKPDIHFFHCDEVEAELVQEDIESALADYRLGKKMRPQTLKGHQEKIRQRQSILPPPQSPAPIPFQRQPGDSPQAKNRVGLPLPVPFSEPGYRRRESQDEEPRAVLAQRIEKETQILNCTLDDIEWFVARLQKAAEAFKQLNQRKKGKKKNKKGPAEGVLTLRARPPSEGEFVDCFQKTKLAINLLAKLQKHIQNPSAAELVHFLFGPLDLIINTCGSPDIARSVSSPLLSTDAVSFLRGHLVPKEMTLWESLGETWMRPRSEWPREPQVPLYVPKFRSGWEPPLDVLQEAPWEVEGLASVPSDQLTPKNRLSVRHSPKHSLSSESQAPEDIAPPGSSPHANRGYQPTPAMTKYVKILYDFTARNANELSVLKDEVLEVLEDGRQWWKLRNRSGQAGYVPCNILAEARQEDVGAPLEQSGQKYWGPASPTHKLPPIFAGNKEELIHHMDEVNDELMKKISHIKTQPQRNFRVERSQPVHLPLTFESGPDEVRAWLEAKAFSARIVENLGILTGPQLFSLNKEELKKVCGEEGSRVYSQLTVQKAFLEKQQSGSELEKLMSKIRRAEDSYTSQHTSPESEGAPHL", "length": 729 }, "evidence": [ { "id": "A0A8V0ZP51", "url": "https://omabrowser.org/oma/group/A0A8V0ZP51/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H6S3-1", "protein_name": "Epidermal growth factor receptor kinase substrate 8-like protein 2", "gene_name": "EPS8L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQSGAVSCCPGATNGSLGRSDGVAKMSPKDLFEQRKKYSNSNVIMHETSQYHVQHLATFIMDKSEAITSVDDAIRKLVQLSSKEKIWTQEMLLQVNDQSLRLLDIESQEELEDFPLPTVQRSQTVLNQLRYPSVLLLVCQDSEQSKPDVHFFHCDEVEAELVHEDIESALADCRLGKKMRPQTLKGHQEKIRQRQSILPPPQGPAPIPFQHRGGDSPEAKNRVGPQVPLSEPGFRRRESQEEPRAVLAQKIEKETQILNCALDDIEWFVARLQKAAEAFKQLNQRKKGKKKGKKAPAEGVLTLRARPPSEGEFIDCFQKIKLAINLLAKLQKHIQNPSAAELVHFLFGPLDLIVNTCSGPDIARSVSCPLLSRDAVDFLRGHLVPKEMSLWESLGESWMRPRSEWPREPQVPLYVPKFHSGWEPPVDVLQEAPWEVEGLASAPIEEVSPVSRQSIRNSQKHSPTSEPTPPGDALPPVSSPHTHRGYQPTPAMAKYVKILYDFTARNANELSVLKDEVLEVLEDGRQWWKLRSRSGQAGYVPCNILGEARPEDAGAPFEQAGQKYWGPASPTHKLPPSFPGNKDELMQHMDEVNDELIRKISNIRAQPQRHFRVERSQPVSQPLTYESGPDEVRAWLEAKAFSPRIVENLGILTGPQLFSLNKEELKKVCGEEGVRVYSQLTMQKAFLEKQQSGSELEELMNKFHSMNQRRGEDS", "length": 715 }, "evidence": [ { "id": "A0A8V0ZP51", "url": "https://omabrowser.org/oma/group/A0A8V0ZP51/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" } ], "pmid": "" }, { "name": "stereocilium tip", "id": "GO:0032426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" } ], "pmid": "" }, { "name": "positive regulation of ruffle assembly", "id": "GO:1900029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900029", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP51", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZP51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP51" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 496, "end_pos": 555, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 537, "end_pos": 539 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZP56-1", "uniprot_ac": "A0A8V0ZP56", "uniprot_id": "A0A8V0ZP56_CHICK", "mass": { "chemical_mass": 28727.0, "monoisotopic_mass": 28727.0 }, "refseq": {}, "gene_names": [ { "name": "FAM192A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP56" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 192 member A", "type": "synonym", "evidence": [ { "id": "A0A8V0ZP56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP56/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP56" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM192A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP56", "locus": { "chromosome": "11", "start_pos": 687952, "end_pos": 699753, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022165", "url": "https://www.ensembl.org/id/ENSGALG00010022165" } ] } } ], "crossref": [ { "id": "A0A8V0ZP56", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP56", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR019331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP56", "url": "https://www.orthodb.org/?gene=A0A8V0ZP56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13495", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13495", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13495:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13495:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10187", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10187", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZP56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGGDGSADLVINKRFVSEAELEERRKRRQEEWEKVRKPEDPEECPEEAYDPRSLYERLQEQREKKQQEFEEQFKFKNMVRGLDEDETNFLDEVSRQQELLEKQRREEEMKELNEYRITLTKVGVGMDPKKETEKKLPMKSVENKNKFSQAKLLAGAVKHRSSDGGNSVKRLKLDTDHEEKNQEKPSCVPLGSSSVGGSAVHCPSAAVCIGILPGLGAYSGSSDSESSSDGEGTINSTGKIVSSVFRSNSFFDGP", "length": 255, "header": "tr|A0A8V0ZP56-1|A0A8V0ZP56_CHICK Isoform 1 of Family with sequence similarity 192 member A OS=Gallus gallus OX=9031 GN=FAM192A PE=1 SV=1 CANONICAL=A0A8V0ZP56-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP56/entry#A0A8V0ZP56-1", "sequence": { "sequence": "MDGGDGSADLVINKRFVSEAELEERRKRRQEEWEKVRKPEDPEECPEEAYDPRSLYERLQEQREKKQQEFEEQFKFKNMVRGLDEDETNFLDEVSRQQELLEKQRREEEMKELNEYRITLTKVGVGMDPKKETEKKLPMKSVENKNKFSQAKLLAGAVKHRSSDGGNSVKRLKLDTDHEEKNQEKPSCVPLGSSSVGGSAVHCPSAAVCIGILPGLGAYSGSSDSESSSDGEGTINSTGKIVSSVFRSNSFFDGP", "length": 255, "header": "tr|A0A8V0ZP56-1|A0A8V0ZP56_CHICK Isoform 1 of Family with sequence similarity 192 member A OS=Gallus gallus OX=9031 GN=FAM192A PE=1 SV=1 CANONICAL=A0A8V0ZP56-1" }, "locus": { "chromosome": "11", "start_pos": 697725, "end_pos": 690187, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053914.1", "url": "https://www.ensembl.org/id/ENSGALT00010053914.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032466.1", "url": "https://www.ensembl.org/id/ENSGALP00010032466.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP56" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP56" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of proteasomal protein catabolic process", "id": "GO:1901799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901799", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP56", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZP56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP56" }, { "id": "PF10187", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10187" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM192A/Fyv6 N-terminal", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 117, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZR01-1", "uniprot_ac": "A0A8V0ZR01", "uniprot_id": "A0A8V0ZR01_CHICK", "mass": { "chemical_mass": 76624.0, "monoisotopic_mass": 76624.0 }, "refseq": { "ac": "XP_015152138", "name": "RBBP8 N-terminal-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152138" }, "gene_names": [ { "name": "RBBP8NL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR01" } ] }, { "name": "RBBP8NL", "type": "synonym", "evidence": [ { "id": "XP_015152138", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152138" } ] } ], "protein_names": [ { "name": "RBBP8 N-terminal like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR01/entry#names_and_taxonomy" } ] }, { "name": "RBBP8 N-terminal-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015152138", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152138" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015152138.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152138", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152138" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR01" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RBBP8NL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR01", "locus": { "chromosome": "20", "start_pos": 8303979, "end_pos": 8320290, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022609", "url": "https://www.ensembl.org/id/ENSGALG00010022609" } ] } } ], "crossref": [ { "id": "A0A8V0ZR01", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR01", "database": "AlphaFoldDB", "categories": [] }, { "id": "101747728", "url": "https://www.ncbi.nlm.nih.gov/gene/101747728", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RCQVTQE", "url": "https://omabrowser.org/oma/group/RCQVTQE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP59", "url": "https://www.orthodb.org/?gene=A0A8V0ZP59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR01", "url": "https://www.orthodb.org/?gene=A0A8V0ZR01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15107:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15107:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10482", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10482", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015152138", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152138", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP59", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTESFAEFLNKLKEIHEREVQGLQTKLTELTTEKCRDAQRIEELFAKNHQLREQQKVLKENVKVLENRLRAGLCDRCMVTQELAKKKQNEYENSHFQSLQHIFILTNEMSRLKEENKALKEELKRLQSPEDRTKYPGVISREHSSTPSSPLPLLSPTSRNTSIERVALGAAEDSQHGVPGLELGEEKATGQRSSPSSRVSPSTVLQEASLAEMASQRIANQLHGTIALVRHSLEKSPSGAAVSPPARKTLLPPEQERSPSLEPYLTTTKPISPKIVPSYESLKLTARKEQLCLLNKHLALHQLGLTSGCAPSDGDSSFHRQLLRATDGDGRTRPRDDWDDRAALLKLPAAVVYVRDQHLEGKLHLLKHHERLQHLEQQRSHRVRVDGEPKAVSKERPLSPCLSITVGCKEERMEDAEDGKVERELWLSRDGSEHRGKAESLRDYGVDAPLDLSDTGRGKGMGWIKHQEANSPRLSPGDSPMHGPCRRHGMERDSSQPHSCWHDAAQTQLTGQPGAIKEEEEEEEEETAVLALSRVHPINKSTASNTETPPEPRVRLVASAQKEEPGKELQASLTSEKSNAKDDDDDESAKQESDEADTTDSEVASPYERDVLQEAQSEGKYFCTKDRAHVLQKKRRRGQDSWTKGSKKAVRGRKKVKVEQCSLEMTEEAESCLASHHDPSEDS", "length": 684, "header": "tr|A0A8V0ZR01-1|A0A8V0ZR01_CHICK Isoform 1 of RBBP8 N-terminal like OS=Gallus gallus OX=9031 GN=RBBP8NL PE=4 SV=1 CANONICAL=A0A8V0ZR01-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR01/entry#A0A8V0ZP59-1", "sequence": { "sequence": "MTTESFAEFLNKLKEIHEREVQGLQTKLTELTTEKCRDAQRIEELFAKNHQLREQQKVLKENVKVLENRLRAGLCDRCMVTQELAKKKQNEYENSHFQSLQHIFILTNEMSRLKEENKALKEELKRLQSPETKYPGVISREHSSTPSSPLPLLSPTSRNTSIERVALGAAEDSQHGVPGLELGEEKATGQRSSPSSRVSPSTVLQEASLAEMASQRIANQLHGTIALVRHSLEKSPSGAAVSPPARKTLLPPEQERSPSLEPYLTTTKPISPKIVPSYESLKLTARKEQLCLLNKHLALHQLGLTSGCAPSDGDSSFHRQLLRATDGDGRTRPRDDWDDRAALLKLPAAVVYVRDQHLEGKLHLLKHHERLQHLEQQRSHRVRVDGEPKAVSKERPLSPCLSITVGCKEERMEDAEDGKVERELWLSRDGSEHRGKAESLRDYGVDAPLDLSDTGRGKGMGWIKHQEANSPRLSPGDSPMHGPCRRHGMERDSSQPHSCWHDAAQTQLTGQPGAIKEEEEEEEEETAVLALSRVHPINKSTASNTETPPEPRVRLVASAQKEEPGKELQASLTSEKSNAKDDDDDESAKQESDEADTTDSEVASPYERDVLQEAQSEGKYFCTKDRAHVLQKKRRRGQDSWTKGSKKAVRGRKKVKVEQCSLEMTEEAESCLASHHDPSEDS", "length": 682, "header": "tr|A0A8V0ZP59-1|A0A8V0ZR01_CHICK Computationally mapped isoform of RBBP8 N-terminal like OS=Gallus gallus OX=9031 GN=RBBP8NL PE=4 SV=1 CANONICAL=A0A8V0ZR01-1" }, "locus": { "chromosome": "20", "start_pos": 8314882, "end_pos": 8304946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055015.1", "url": "https://www.ensembl.org/id/ENSGALT00010055015.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033263.1", "url": "https://www.ensembl.org/id/ENSGALP00010033263.1" } ] } }, { "isoform_ac": "A0A8V0ZR01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR01/entry#A0A8V0ZR01-1", "sequence": { "sequence": "MTTESFAEFLNKLKEIHEREVQGLQTKLTELTTEKCRDAQRIEELFAKNHQLREQQKVLKENVKVLENRLRAGLCDRCMVTQELAKKKQNEYENSHFQSLQHIFILTNEMSRLKEENKALKEELKRLQSPEDRTKYPGVISREHSSTPSSPLPLLSPTSRNTSIERVALGAAEDSQHGVPGLELGEEKATGQRSSPSSRVSPSTVLQEASLAEMASQRIANQLHGTIALVRHSLEKSPSGAAVSPPARKTLLPPEQERSPSLEPYLTTTKPISPKIVPSYESLKLTARKEQLCLLNKHLALHQLGLTSGCAPSDGDSSFHRQLLRATDGDGRTRPRDDWDDRAALLKLPAAVVYVRDQHLEGKLHLLKHHERLQHLEQQRSHRVRVDGEPKAVSKERPLSPCLSITVGCKEERMEDAEDGKVERELWLSRDGSEHRGKAESLRDYGVDAPLDLSDTGRGKGMGWIKHQEANSPRLSPGDSPMHGPCRRHGMERDSSQPHSCWHDAAQTQLTGQPGAIKEEEEEEEEETAVLALSRVHPINKSTASNTETPPEPRVRLVASAQKEEPGKELQASLTSEKSNAKDDDDDESAKQESDEADTTDSEVASPYERDVLQEAQSEGKYFCTKDRAHVLQKKRRRGQDSWTKGSKKAVRGRKKVKVEQCSLEMTEEAESCLASHHDPSEDS", "length": 684, "header": "tr|A0A8V0ZR01-1|A0A8V0ZR01_CHICK Isoform 1 of RBBP8 N-terminal like OS=Gallus gallus OX=9031 GN=RBBP8NL PE=4 SV=1 CANONICAL=A0A8V0ZR01-1" }, "locus": { "chromosome": "20", "start_pos": 8314882, "end_pos": 8304946, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055019.1", "url": "https://www.ensembl.org/id/ENSGALT00010055019.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033265.1", "url": "https://www.ensembl.org/id/ENSGALP00010033265.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTF0-1", "protein_name": "RBBP8 N-terminal like", "gene_name": "Rbbp8nl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSFMESLNRLKEAHEKEVLGLQNKLLELNSERCRDAQRVEELFAKNHQLREQQKALKENLRVLENRLRAGLCDRCMVTQELARKKQLELESAHLQSLQHLCVLTNEMNVLREENKILKEEVKRLRNLGDKTTPQTWEGTSEPPSPLPLPSPSNRKGATENPPGGSEEAEEEQGTDKLSSHKTSPVARVSPATNLLEPRTLDMTPQCISNQLHSTVAVVRPGSRACPPDSDTANGTPPPPSMRSSPSSPTYEHGLPVDSFLRAARPSAIAYETLKHSLQTDRLCLLNRHLSLHLQSPHSSLLTPAAAPNSPLPRGLKAREAEAWEEPSALVGVQDPRLEGALHLLLVQQHLRARARASTARLRVPSAPKEMPSSPPADSDSESSDSEAPKPVLSTEAQPDGWHPPPIGQSSSQRKETLVATQDSPPDKPLDLSDRGRCRDTSKSTGQPLPLSPTPDPQLPALSRPLILSSHTLSNGSTETRAQESEEYSTPKDTSQTLSGIHVGLTSPRRTAEEPGGRPRPGPHLQRPDADGTTAQRPELEQLGESDASDTKAGLISESSIETSIAGEGQHAEDLRRGQQQKRKRASDLQDKAPKKPSQGKRKPKEPLTPADGPRSPRDTEDYSLSPINSCRES", "length": 634 }, "evidence": [ { "id": "A0A8V0ZR01", "url": "https://omabrowser.org/oma/group/A0A8V0ZR01/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2ABX0-1", "protein_name": "RBBP8 N-terminal like", "gene_name": "Rbbp8nl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSFMESLNRLKEAHEKEVLGLQNKLLELNSERCRDAQRVEELFAKNHQLREQQKALKENLRVLENRLRAGLCDRCMVTQELARKKQLELENAHLQSLQHLCILTNEMNGLREENKILKEEVKRLRSLGDKTAPQAWEGTSEPPSPLPLPSPSSWKGTTENPPGAPEEAEEEQSGTDKISSHKTSPVSRVSPAANLPEPRALDMTPQCISNQLHSTVAVVRPGSRACPPDSGSADGTPPPSTRSTPPSPTYEHGLPVDSFLRASRPSAIAYETLKHSLQTDRLCLLNRQLSLRLQSPHSSPLASAVAPHSPLPRGLKAREAEAWEEPGALVGMQDPRLEGALHLLLVQQHLRARARASTARLQVPSAPEEMPSSPPAGSDSEGSDSEAPKPALSTEAQPDGWHPQTTGQGSSQRKETHVATQDCPPDKPLDLSDRGRCRDISKSTGQPLPLSPKIVYTPSPQLPTLSRPLVPSSHTLSNVSTETRAQESEEYSTPKDTSHPLPGVCMGLTSPGRTAEEAGGRPQPGPHLQRPDTGGTTEPKKVRAQRLALEQLEESDTSDTKAGLISEASAEPSMPGVGHAEDHQQSQQQKRKRASDLQDKGTYLREGKAGPGM", "length": 614 }, "evidence": [ { "id": "A0A8V0ZR01", "url": "https://omabrowser.org/oma/group/A0A8V0ZR01/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BI77-1", "protein_name": "RBBP8 N-terminal like", "gene_name": "RBBP8NL", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRTRDHAGNRGPVEAKGPSPHLEHRGPRARATGAMESFTESLNRLKEVHENEVMGLQNKLMELNSERCRDAQRVEELCAKNHQLREQQKALKENLRALENRLRAGLCDRCMVTQELARKKQQEFESSLLQNLQHVFLLTTELTRLQEENDALKEEVKRLQGPGPKPQLREGISDPPSPLLLPSLGARKAVTEKPLGGHEETEDGRAERPGVYGTSPMAKISPSPNLHEARTPDMVRNPQRISNQLHGTIAVVRPGSRACSADQGSTNGTPPLLPTRNSPPSPPGEHSLPLDSFLQASRPSARTCESLKHSLQADRLCLLNRHLTLHLGSPPAPATAPSGPQSQGLKAGEAEAWEEPSGLLGLPGALVGVRNPRLEGALHMLLAQQLRAQGRVGSARLRGPWGPRGTPPSPPADSDSEGPEGEAARETLSRRRHPQPAGPGSPQGKEGTATQDYVPDKPLDLSERGRCRASTPKPANQSGSLSPPQVPTPSPEPPQGVGPPAQCGAQRLSNGTQEAKEPEAEEHPSSPDPPYSAPGPHLSLPSPSGPGEEDRGRPRLPPYPPRPGGDSHPELSKVHGQQLESDELDEPDTSDSEMVLSTRAEATESSPGEGPGCVCDKECGRGPQKRKRASDSWSKASKKPT", "length": 641 }, "evidence": [ { "id": "A0A8V0ZR01", "url": "https://omabrowser.org/oma/group/A0A8V0ZR01/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8NC74-1", "protein_name": "RBBP8 N-terminal-like protein", "gene_name": "RBBP8NL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESFMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRVLENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRLRGLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSPWEET", "length": 664 }, "evidence": [ { "id": "A0A8V0ZR01", "url": "https://omabrowser.org/oma/group/A0A8V0ZR01/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZR01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR01" }, { "id": "PF10482", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10482" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DNA endonuclease Ctp1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 125, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZP65-1", "uniprot_ac": "A0A8V0ZP65", "uniprot_id": "A0A8V0ZP65_CHICK", "mass": { "chemical_mass": 15006.0, "monoisotopic_mass": 15006.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZP65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP65/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP65" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP65", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZP65", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP65", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR46282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46282:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46282:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGLVVSGAQVSYISQDCEEIPEFLGRKYGHMAKRLDLSFNLLRSLEGLKTFSYLEELILDNNLLGNDLLLPRLPHLHTLTLNKNQISFQRNTCKMSNEFYVSAKLKYVKYSSRADKAFSRLAPGILHSNLL", "length": 132, "header": "tr|A0A8V0ZP65-1|A0A8V0ZP65_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZP65-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP65/entry#A0A8V0ZP65-1", "sequence": { "sequence": "MAGLVVSGAQVSYISQDCEEIPEFLGRKYGHMAKRLDLSFNLLRSLEGLKTFSYLEELILDNNLLGNDLLLPRLPHLHTLTLNKNQISFQRNTCKMSNEFYVSAKLKYVKYSSRADKAFSRLAPGILHSNLL", "length": 132, "header": "tr|A0A8V0ZP65-1|A0A8V0ZP65_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZP65-1" }, "locus": { "chromosome": "6", "start_pos": 15323287, "end_pos": 14975687, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054076.1", "url": "https://www.ensembl.org/id/ENSGALT00010054076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032607.1", "url": "https://www.ensembl.org/id/ENSGALP00010032607.1" } ] } }, { "isoform_ac": "A0A8V0ZUU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP65/entry#A0A8V0ZUU2-1", "sequence": { "sequence": "MKLGFSQKMVSYISQDCEEIPEFLGRKYGHMAKRLDLSFNLLRSLEGLKTFSYLEELILDNNLLGNDLLLPRLPHLHTLTLNKNQISFQRNTCKMSNEFYVSAKLKYVKYSSRADKAFSRLAPGILHSNLL", "length": 131, "header": "tr|A0A8V0ZUU2-1|A0A8V0ZP65_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZP65-1" }, "locus": { "chromosome": "6", "start_pos": 15322783, "end_pos": 14975687, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054073.1", "url": "https://www.ensembl.org/id/ENSGALT00010054073.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032604.1", "url": "https://www.ensembl.org/id/ENSGALP00010032604.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "melanocyte differentiation", "id": "GO:0030318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030318", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZP76-1", "uniprot_ac": "A0A8V0ZP76", "uniprot_id": "A0A8V0ZP76_CHICK", "mass": { "chemical_mass": 34841.0, "monoisotopic_mass": 34841.0 }, "refseq": { "ac": "XP_040534290", "name": "PDZ domain-containing protein GIPC2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534290" }, "gene_names": [ { "name": "GIPC2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP76" } ] }, { "name": "GIPC2", "type": "synonym", "evidence": [ { "id": "XP_040534290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534290" } ] } ], "protein_names": [ { "name": "GIPC PDZ domain containing family member 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZP76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP76/entry#names_and_taxonomy" } ] }, { "name": "PDZ domain-containing protein GIPC2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040534290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534290" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052580.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040534290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534290" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP76" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GIPC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP76", "locus": { "chromosome": "8", "start_pos": 18524196, "end_pos": 18548809, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022172", "url": "https://www.ensembl.org/id/ENSGALG00010022172" } ] } } ], "crossref": [ { "id": "A0A8V0ZP76", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP76", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06707", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06707", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21180", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21180", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424549", "url": "https://www.ncbi.nlm.nih.gov/gene/424549", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424549", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424549", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VGWRHYE", "url": "https://omabrowser.org/oma/group/VGWRHYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP76", "url": "https://www.orthodb.org/?gene=A0A8V0ZP76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12259", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12259", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12259:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12259:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25082", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25082", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040534290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040534290", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLGLGTRKKGKSKETSKLVDSEATAPPSAAEAPAPAASASRLQFHTQLAHGSPTGRVEGFGSARELYAKIAEVFGISPTEIMFCTLNTHKVDMDKLLGAQIGLEDFIFAHIKGQRKEVEVLKSDDLLGLTVTDNGAGCPFIKRIKEGSLMDQTKMICVGDHIESINGRDVSDLRHYEVAKMLKDLEKGRVFKLKLIEPMKSFEKVAARSKGGTLTEAKISRGRETLRLRNKGPATVEEMLSEVEEKAVKKVDELLETYMGIRDIELAATMVEAGRDKKNPDEFAVALDETLGDFAFPDEFVFDVWGAIGDAKQGRLE", "length": 318, "header": "tr|A0A8V0ZP76-1|A0A8V0ZP76_CHICK Isoform 1 of GIPC PDZ domain containing family member 2 OS=Gallus gallus OX=9031 GN=GIPC2 PE=1 SV=1 CANONICAL=A0A8V0ZP76-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP76/entry#A0A8V0ZP76-1", "sequence": { "sequence": "MPLGLGTRKKGKSKETSKLVDSEATAPPSAAEAPAPAASASRLQFHTQLAHGSPTGRVEGFGSARELYAKIAEVFGISPTEIMFCTLNTHKVDMDKLLGAQIGLEDFIFAHIKGQRKEVEVLKSDDLLGLTVTDNGAGCPFIKRIKEGSLMDQTKMICVGDHIESINGRDVSDLRHYEVAKMLKDLEKGRVFKLKLIEPMKSFEKVAARSKGGTLTEAKISRGRETLRLRNKGPATVEEMLSEVEEKAVKKVDELLETYMGIRDIELAATMVEAGRDKKNPDEFAVALDETLGDFAFPDEFVFDVWGAIGDAKQGRLE", "length": 318, "header": "tr|A0A8V0ZP76-1|A0A8V0ZP76_CHICK Isoform 1 of GIPC PDZ domain containing family member 2 OS=Gallus gallus OX=9031 GN=GIPC2 PE=1 SV=1 CANONICAL=A0A8V0ZP76-1" }, "locus": { "chromosome": "8", "start_pos": 18548706, "end_pos": 18526717, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010053933.1", "url": "https://www.ensembl.org/id/ENSGALT00010053933.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032481.1", "url": "https://www.ensembl.org/id/ENSGALP00010032481.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424549", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424549", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BNZ1-1", "protein_name": "GIPC PDZ domain containing family member 2", "gene_name": "GIPC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLGLLRKKKPKSKETSRLVEGEQADAAGSSLPHPTVPTRRLVFHTQLAHGSATGRVEDFSSIKELYAKIAGVFEISPSEILYCTLNTPKVDMGKLLGTQIGLEDFIFAHVKGIKKEVNVYKSEDSLGLTITDNGAGYAFIKRIKDGSVIDSVKTICVGDHIESINGENIVGWRHFDVAKKLKELKKEELFTLKLIEPKKAFEIEPRSKAGKSSTEKIGTGRETLRLRSKGPATVEEVPSEAKTKAIEKIDDLLELYMGIRDIDLATTMFEAGKDKGNPDEFAVALDETLGDFAFPDEFVFDVWGVIGDAKRE", "length": 313 }, "evidence": [ { "id": "A0A8V0ZP76", "url": "https://omabrowser.org/oma/group/A0A8V0ZP76/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1JQD4-1", "protein_name": "PDZ domain-containing protein GIPC2", "gene_name": "GIPC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLGLRRKKKFNTKETSRLVEGEHTDAAVRSLPSPPAPARRLVFHTQLAHGSATGRVENFSSIQELYAKIAGVFEIPPSEILYCTLNTPKVDMGKLLGAQIGLEDFIFAHIKGIKKEVNVYKSEDSLGLTITDNGAGYAFIKRIKDDSIIDSVKTICVGDHIEAINGENIVGWRHFDVAKKLKELKKEELFTLTLIEPKKAFDMEPRSKAGKSSTGKIGTGRETLRLRSKGPATVEEVPSEAKEKAIGKVDDLLELYMGIRDTDLATTMFEAGKDKGNPDEFAVALDETLGDFAFPDEFVFDVWGVIGDAKQE", "length": 313 }, "evidence": [ { "id": "A0A8V0ZP76", "url": "https://omabrowser.org/oma/group/A0A8V0ZP76/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q498D9-1", "protein_name": "PDZ domain-containing protein GIPC2", "gene_name": "Gipc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLGLRGKKKAAKSKETARLVEGERSGGSQGVPGPPAPARRLVFHAQLAHGSATGRVEDFSSISELYAKIAGVFEIAPSEILFCTLNTPKIDMGKLLGGQLGLEDFIFAHVKGIKKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGSTIDSVKTICVGDHIECINGENIVGWRHFEVAKKLKELKKEELFTLQLIEPKKAFEIGPRSKAGKTSTEKIGTSRGTLRLRSKGPATVEDLPSEAKAKAIEKVDDLLELYMGIRDIDLATTMFEAGKDKSNPDEFAVALDETLGDFAFPDEFMFDVWGAISDVKQGR", "length": 314 }, "evidence": [ { "id": "A0A8V0ZP76", "url": "https://omabrowser.org/oma/group/A0A8V0ZP76/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TF65-1", "protein_name": "PDZ domain-containing protein GIPC2", "gene_name": "GIPC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLKLRGKKKAKSKETAGLVEGEPTGAGGGSLSASRAPARRLVFHAQLAHGSATGRVEGFSSIQELYAQIAGAFEISPSEILYCTLNTPKIDMERLLGGQLGLEDFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKAFEIELRSKAGKSSGEKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMGIRDIDLATTMFEAGKDKVNPDEFAVALDETLGDFAFPDEFVFDVWGVIGDAKRRGL", "length": 315 }, "evidence": [ { "id": "A0A8V0ZP76", "url": "https://omabrowser.org/oma/group/A0A8V0ZP76/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2H7-1", "protein_name": "PDZ domain-containing protein GIPC2", "gene_name": "Gipc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLGLRGKKKAAKSKEAARLVEGERSSGSQGVPGPPAPARKLVFHAQLAHGSATGRVEDFSSISELYAKIAGVFEIAPSEILFCTLNTPKIDMGKLLGGQLGLEDFIFAHVKGTKKEVNVYKSEDSLGLTITDNGVGYAFIKRIKDGSTIDSVKTICVGDHIECINGENIVGWRHFEVAKKLKELKKEELFTLQLIEPKKAFEIGPRSKAGKTSTEKIGTSRGTLRLRSKGPATVEELPSEAKAKAIGKVDDLLELYMGIRDIDLATTMFEAGKDKSNPDEFAVALDETLGDFAFPDEFLFDVWGAISDMKQGR", "length": 314 }, "evidence": [ { "id": "A0A8V0ZP76", "url": "https://omabrowser.org/oma/group/A0A8V0ZP76/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP76" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZP76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP76" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 118, "end_pos": 185, "start_aa": "Glu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZP82-1", "uniprot_ac": "A0A8V0ZP82", "uniprot_id": "A0A8V0ZP82_CHICK", "mass": { "chemical_mass": 7687.0, "monoisotopic_mass": 7687.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Growth arrest specific 2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP82/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP82" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP82", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZP82", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP82", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0ZP82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYTALSPKTRGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLEPTYQIQMITIPKLIPSSFV", "length": 67, "header": "tr|A0A8V0ZP82-1|A0A8V0ZP82_CHICK Isoform 1 of Growth arrest specific 2 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZP82-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP82/entry#A0A8V0ZP82-1", "sequence": { "sequence": "MYTALSPKTRGPGLSDMHQYSQWLASRHEANLLPMKEDLALWLTNLLEPTYQIQMITIPKLIPSSFV", "length": 67, "header": "tr|A0A8V0ZP82-1|A0A8V0ZP82_CHICK Isoform 1 of Growth arrest specific 2 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZP82-1" }, "locus": { "chromosome": "5", "start_pos": 3163245, "end_pos": 3160567, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055054.1", "url": "https://www.ensembl.org/id/ENSGALT00010055054.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033288.1", "url": "https://www.ensembl.org/id/ENSGALP00010033288.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZP92-1", "uniprot_ac": "A0A8V0ZP92", "uniprot_id": "A0A8V0ZP92_CHICK", "mass": { "chemical_mass": 107553.0, "monoisotopic_mass": 107553.0 }, "refseq": { "ac": "XP_015146641", "name": "KN motif and ankyrin repeat domain-containing protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146641" }, "gene_names": [ { "name": "KANK4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92" } ] }, { "name": "KANK4", "type": "synonym", "evidence": [ { "id": "XP_015146641", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146641" } ] } ], "protein_names": [ { "name": "KN motif and ankyrin repeat domain-containing protein 4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92/entry#names_and_taxonomy" } ] }, { "name": "Ankyrin repeat domain-containing protein 38", "type": "synonym", "evidence": [ { "id": "A0A8V0ZP92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92/entry#names_and_taxonomy" } ] }, { "name": "KN motif and ankyrin repeat domain-containing protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015146641", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146641" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015146641.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146641" } ] }, { "annotation": "May be involved in the control of cytoskeleton formation by regulating actin polymerization.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92#function" }, { "database": "UniProtKB", "id": "ARBA00059781", "url": "https://www.uniprot.org/uniprotkb/ARBA00059781#function" }, { "database": "UniProtKB", "id": "A0A8V0ZY43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY43#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KANK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92", "locus": { "chromosome": "8", "start_pos": 27148947, "end_pos": 27167017, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023821", "url": "https://www.ensembl.org/id/ENSGALG00010023821" } ] } } ], "crossref": [ { "id": "A0A8V0ZP92", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZP92", "database": "AlphaFoldDB", "categories": [] }, { "id": "424684", "url": "https://www.ncbi.nlm.nih.gov/gene/424684", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424684", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424684", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QSCQGDE", "url": "https://omabrowser.org/oma/group/QSCQGDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP92", "url": "https://www.orthodb.org/?gene=A0A8V0ZP92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZY43", "url": "https://www.orthodb.org/?gene=A0A8V0ZY43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24168", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24168", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24168:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24168:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015146641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146641", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY43-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKTDAAGQPPLPNGDGEQPRSLPYSLETPYGFHLDLDFLKYVDDIEKGNTIRRVHIHRKAKQPKFSTLPRNFSLPENGSHGYAASTGPGWPAATYRAQRKASLGAEEISRAPLPSEEPSYRRKALLAETRRHAELVRCEDELRGRPQLLRASSLPAALPPGQAPASDGCVPCPLLPSDNGSCPESTFRPMPRSPDGIASLPSLMLSPGAELASQQQEWPGKGGLVRDVPKERAQPLWQGQHSAVQLQVVMESRGEEGDASDATNGSTLVSASPGALQLADESTNHGKAGGSVSEIALNVLKEGEGRCAHAQEKKEQGGDAGEPGGIAALKQHIAALEEQLDRKKEELEQIRAVLKQQDHKIKEKEKSIQLLASSKAQLEEQLCRENTREDAVSSMQRGSMLQCNDVAVNTELSYVNGSKQVHDKGINVNIPLSTKSIGCGIRRADNGNLLAAELSAQGWADVGTSGGGDGHFAKLSETEAGLEPGLHAPGFTELKIDEQLSDDNQNQRNSCDTQSLAARAAAAESYRTKRTGSSADENEAGFGEDKTEDGMGEEGLPDPKDFPAVDPIGQYVKKIQELLQEQWMCLEHGYPELASAIKQPASKLSSIQNQLVNSLNSLLSAYSSQRPADKENSNTHYQQLETSSTTSLKSIMKKKGYGSHAGGNGTKKNLQFVGVNGGYETTSSEDTSCEDSPSDGDMESDTERGAGGLEPTQEQGGGGSEGASFVTSVQETREDDDLQEPGAETAPCTQHKADSCKPSEDFLAACQLLSQHLSEIRATSDQHLRHVLSTICQEWFQVSSRKSSSPEVVTAYLQALGTIQPQLLEAVVNMADRNGNTALHYSISHSNFTIAKLLLDTGVCRLDLPNQAGYTAVMLTPLVAAETDEDMAVVMRLLKEGDVNVRAAQGGQTALMLGVSHEREAMVRALLACHADVNLQDEQGSTALMVACRQGSTDMVRLLLAQPGCQLALTDKDGDTALSIAQRSAHEDIAALLHSAQHGPND", "length": 1003, "header": "tr|A0A8V0ZP92-1|A0A8V0ZP92_CHICK Isoform 1 of KN motif and ankyrin repeat domain-containing protein 4 OS=Gallus gallus OX=9031 GN=KANK4 PE=1 SV=1 CANONICAL=A0A8V0ZP92-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92/entry#A0A8V0ZP92-1", "sequence": { "sequence": "MEKTDAAGQPPLPNGDGEQPRSLPYSLETPYGFHLDLDFLKYVDDIEKGNTIRRVHIHRKAKQPKFSTLPRNFSLPENGSHGYAASTGPGWPAATYRAQRKASLGAEEISRAPLPSEEPSYRRKALLAETRRHAELVRCEDELRGRPQLLRASSLPAALPPGQAPASDGCVPCPLLPSDNGSCPESTFRPMPRSPDGIASLPSLMLSPGAELASQQQEWPGKGGLVRDVPKERAQPLWQGQHSAVQLQVVMESRGEEGDASDATNGSTLVSASPGALQLADESTNHGKAGGSVSEIALNVLKEGEGRCAHAQEKKEQGGDAGEPGGIAALKQHIAALEEQLDRKKEELEQIRAVLKQQDHKIKEKEKSIQLLASSKAQLEEQLCRENTREDAVSSMQRGSMLQCNDVAVNTELSYVNGSKQVHDKGINVNIPLSTKSIGCGIRRADNGNLLAAELSAQGWADVGTSGGGDGHFAKLSETEAGLEPGLHAPGFTELKIDEQLSDDNQNQRNSCDTQSLAARAAAAESYRTKRTGSSADENEAGFGEDKTEDGMGEEGLPDPKDFPAVDPIGQYVKKIQELLQEQWMCLEHGYPELASAIKQPASKLSSIQNQLVNSLNSLLSAYSSQRPADKENSNTHYQQLETSSTTSLKSIMKKKGYGSHAGGNGTKKNLQFVGVNGGYETTSSEDTSCEDSPSDGDMESDTERGAGGLEPTQEQGGGGSEGASFVTSVQETREDDDLQEPGAETAPCTQHKADSCKPSEDFLAACQLLSQHLSEIRATSDQHLRHVLSTICQEWFQVSSRKSSSPEVVTAYLQALGTIQPQLLEAVVNMADRNGNTALHYSISHSNFTIAKLLLDTGVCRLDLPNQAGYTAVMLTPLVAAETDEDMAVVMRLLKEGDVNVRAAQGGQTALMLGVSHEREAMVRALLACHADVNLQDEQGSTALMVACRQGSTDMVRLLLAQPGCQLALTDKDGDTALSIAQRSAHEDIAALLHSAQHGPND", "length": 1003, "header": "tr|A0A8V0ZP92-1|A0A8V0ZP92_CHICK Isoform 1 of KN motif and ankyrin repeat domain-containing protein 4 OS=Gallus gallus OX=9031 GN=KANK4 PE=1 SV=1 CANONICAL=A0A8V0ZP92-1" }, "locus": { "chromosome": "8", "start_pos": 27159382, "end_pos": 27149729, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058058.1", "url": "https://www.ensembl.org/id/ENSGALT00010058058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035236.1", "url": "https://www.ensembl.org/id/ENSGALP00010035236.1" } ] } }, { "isoform_ac": "A0A8V0ZY43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92/entry#A0A8V0ZY43-1", "sequence": { "sequence": "MEKTDAGQPPLPNGDGEQPRSLPYSLETPYGFHLDLDFLKYVDDIEKGNTIRRVHIHRKAKQPKFSTLPRNFSLPENGSHGYAASTGPGWPAATYRAQRKASLGAEEISRAPLPSEEPSYRRKALLAETRRHAELVRCEDELRGRPQLLRASSLPAALPPGQAPASDGCVPCPLLPSDNGSCPESTFRPMPRSPDGIASLPSLMLSPGAELASQQQEWPGKGGLVRDVPKERAQPLWQGQHSAVQLQVVMESRGEEGDASDATNGSTLVSASPGALQLADESTNHGKAGGSVSEIALNVLKEGEGRCAHAQEKKEQGGDAGEPGGIAALKQHIAALEEQLDRKKEELEQIRAVLKQQDHKIKEKEKSIQLLASSKAQLEEQLCRENTREDAVSSMQRGSMLQCNDVAVNTELSYVNGSKQVHDKGINVNIPLSTKSIGCGIRRADNGNLLAAELSAQGWADVGTSGGGDGHFAKLSETEAGLEPGLHAPGFTELKIDEQLSDDNQNQRNSCDTQSLAARAAAAESYRTKRTGSSADENEAGFGEDKTEDGMGEEGLPDPKDFPAVDPIGQYVKKIQELLQEQWMCLEHGYPELASAIKQPASKLSSIQNQLVNSLNSLLSAYSSQRPADKENSNTHYQQLETSSTTSLKSIMKKKGYGSHAGGNGTKKNLQFVGVNGGYETTSSEDTSCEDSPSDGDMESDTERGAGGLEPTQEQGGGGSEGASFVTSVQETREDDDLQEPGAETAPCTQHKADSCKPSEDFLAACQLLSQHLSEIRATSDQHLRHVLSTICQEWFQVSSRKSSSPEVVTAYLQALGTIQPQLLEAVVNMADRNGNTALHYSISHSNFTIAKLLLDTGVCRLDLPNQAGYTAVMLTPLVAAETDEDMAVVMRLLKEGDVNVRAAQGGQTALMLGVSHEREAMVRALLACHADVNLQDEQGSTALMVACRQGSTDMVRLLLAQPGCQLALTDKDGDTALSIAQRSAHEDIAALLHSAQHGPND", "length": 1002, "header": "tr|A0A8V0ZY43-1|A0A8V0ZP92_CHICK Computationally mapped isoform of KN motif and ankyrin repeat domain-containing protein 4 OS=Gallus gallus OX=9031 GN=KANK4 PE=1 SV=1 CANONICAL=A0A8V0ZP92-1" }, "locus": { "chromosome": "8", "start_pos": 27159382, "end_pos": 27149729, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058062.1", "url": "https://www.ensembl.org/id/ENSGALT00010058062.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035239.1", "url": "https://www.ensembl.org/id/ENSGALP00010035239.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424684", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424684", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A6X3-1", "protein_name": "KN motif and ankyrin repeat domain-containing protein 4", "gene_name": "Kank4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKMDGRQFLSPDLKAKDQSPQGDEEKEPPKSYPYSVETPYGFHLDLDFLKYVDDIEKGHTIKRIPIHRRAKQAKFSTLPRNFSLPNSGDRSHAAPPQQNWSPVVPRKISLGTQEQSQSVPLGDLPQATVHGNELSYHRKALLAKDTRQVEAGSLEDAGSGRPQLLRASSMPATLPQNQAPEVPNLTSGPSALLVLPPLQDEGSVRDGTFDPAEGLMGFQAAAQSTDRAVEELEPAIPEPVWEGAEPEEGDIKAASHLSQPAPSSSVQNVSVDLEEVDIQHHTRTADLALSPGSSTPSPPPLPSPIPENELSLEEIELNISEIPPPPPIEVDVRSVGVRVTEESLGLVETATSSISSLKSQVLDLEDKLSGRTEELAQVRAALEQQEEETKAREQRIQELECTVAHLEEKLSQEKASDALDRTDAMVNTDPLRELIPRESQDKNIGVNLLSTPVPECWASRAEKNGFPWVQTNHKQSYPSPEEPALPPQLSLPRGPEQILASSLCSCLSMELRIEEEVSEQERDPDGGAGSLSREAGGSPWSRRESAPVIREEASSQLPGAERPGRPASSPQDATIGQYVKKIQELLHEQWNCLEHGYPELASAIKQPASKLSSIQNQLLSSLNLLLSAYSAQAPEPKESPVPPSSTPPPPPEISPSTSLKSIMKKKDYGFRAGGNGTKKNLQFVGVNGGYETTSSEDTSGEDSSPEDLSDSETEKKQDCSEPREDRDMHLSCEAGQGVSKGTGNSGHMSEPRKGVSHMKAERYKPSEEFLNACQALSQHLPEAGATNKQLLRQSLNTISQEWFRVSSRKLSSPEAVAACLLEVQPQSPHLLKLLVNLADRSGNTALHYSVSHSNFAIAKLLLDTGVCNVDHQNKAGYTAVMITPLASPKTKEDMAVVWKLLREGNVNIQATQGGQTALMLGVSHDREDMVQALLSCKADVNLQDHDGSSALMLACHQGNADLVRLLLAHADCNSNLTDKAGQTALSIVLNSPAHVEIAELLRAHSEQGRSLGLKELQKN", "length": 1020 }, "evidence": [ { "id": "A0A8V0ZP92", "url": "https://omabrowser.org/oma/group/A0A8V0ZP92/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6QKN4-1", "protein_name": "KN motif and ankyrin repeat domain-containing protein 4", "gene_name": "KANK4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKTDAKDQSSQGDEEKDPPKSHPYSVETPYGFHLDLDFLKYVDDIEKGNTIKRIPIHRRAKQAKFSTLPRNFSLPDSGARPHAVLSHPNWSPMVSRKVLGTEARAQPLPLGDHPQAPQAASGSEVSYHRKALLMETARQLEAAAAPGEAELTSGSGRPQLLRASSMPATLLQTRASEDPSLNSGPPTPPVLPPLQGEDVVCDGAFGPAEGFAGFSNFTPRAATQPEVRESGDLVPGIPELIQEGPEPPESEKEAPNHLSFPSPPFLSQNALVVLEDAEDQQESREAQVVVTTPSSPTPSPPPLPSPIPENELPLEEIELNISEIPPPPPVEVDVRSVGIRVTEESLGLASLDPGSISCLKQQISDLEGELSGRTEELAQVRAALQRQEEEIKAKGQRIQELECTVAQLVEKLSGGNTKDAQGQTDAMVNTDPLQGLLTRQSCDKSIGVSLLGSMGSESWGARGEGNGLLWGWESHKRGDGSPAGLVSPPQPSLPQGSETVLMPSLHSCLSTELRIEEGGSEQAGGPSVGIKGLDRGVGGSPGSGERKAPPAGREEAGPELSGKERLGRPPSSPTDATIGQYVKKIQELLQEQWSCLEHGYPELARAIKQPASKLSSIQSQLQSSLNLLLSAYSAQAPPQKEPPGPSSSPTMEISPSTSLKSIMKKKDYGFRAGGNGTKKNLQFVGVNGGYETTSSEETSGEDSSPEDLSDSEAEKKCDGPEPRRGKDAHLSCRVGQGTPEGTRDTDQETGPGEELPHPRTERYKPSEEFLNACRVLSQHLPETGTTTDQLLKQSLNTISQEWFRISSRKSSSPAVVASYLHGVQPHSPHLLKLLVNLADGNGNTALHYSVSHSNFSIVKLLLETGVCNVDHQNKAGYTAVMITPLASAETDEDMAVVWKLLREGNVNIQATQGGQTALMLGVSHDRGDMVQALLSCQADVNLQDHDGSSALMLACCHGNTDMVRLLLAHPTCDSSLTDKAGQTALSIALKSPAHVEIAGLLRAHLKQGRSLGP", "length": 1014 }, "evidence": [ { "id": "A0A8V0ZP92", "url": "https://omabrowser.org/oma/group/A0A8V0ZP92/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5T7N3-1", "protein_name": "KN motif and ankyrin repeat domain-containing protein 4", "gene_name": "KANK4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKTDAKDQSSQGDEEKDPPKSHPYSVETPYGFHLDLDFLKYVDDIEKGNTIKRIPIHRRAKQAKFSTLPRNFSLPDSGARPPAAPPLQNWSPVVPREASLGTQEQNQSPPLGNAPQASTSRSEVSYHRKALLAEATRQLEAAEPEDAELTFGSGRPQLLRASSMPATLLHSRASEEPGLSLGPPAPPALPPLQGEGSVCDGTFEPAEGLAGFHSSSPRASTRIPELVQEGAEPPEGVVKVPNHLPLPGPPFSFQNVLVVLEDKEDEHNAREAEVLFTPGSPTPSPPPLPSPIPENELLLEEIELNISEIPPPPPVEVDMRSIGIRVTEESLGLARVDPGSISSLKQQVSALEGELSGRTEELAQVRTALQQQEEEIKAREQRIRELEFTVAQLEGQFHQENAKDTQGQTDVMVNTDPVHGLLTRESCDKGIEVNLLGSMESESWGHRGEENGLLWGPDGHKQGNQSPAERVLLPQLSLPQGPEQVLTSSVHSFLSTELRIEEAGTEQEGGPQGGTRGAGGFLWGSDRKTPPAGREETSSNLPGKEHPGRPPSSPTDATIGQYVKKIQELLQEQWNCLEHGYPELASAIKQPASKLSSIQSQLLSSLNLLLSAYSAQAHPPKEPPASSSSPPVEISPSTSLKSIMKKKDYGFRAGGNGTKKNLQFVGVNGGYETTSSEETSGEDSTPEDLSDSEAEKKCDGPDHKHVKDAHLTCEAGQGIPEGTCHAAQESGPGEEVPHSKAERYKPSEEFLNACRALSQHLPETGTTTDQLLRQSLNTISQEWFRVSSRKSSSPAVVASYLHEVQPHSPHFLKLLVNLADHNGNTALHYSVSHSNFSIVKLLLETGVCNVDHQNKAGYTAVMITPLASAETNEDMAVVWKLLREGNVNIQATQGGQTALMLGVSHDREDMVQALLSCQADVNLQDHDGSSALMVACHHGNVDLVRLLLAHPACDSSLTDKAGRTALSIALKSPTHMEIAGLLRAHAEQGRSLGL", "length": 995 }, "evidence": [ { "id": "A0A8V0ZP92", "url": "https://omabrowser.org/oma/group/A0A8V0ZP92/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P9J5-1", "protein_name": "KN motif and ankyrin repeat domain-containing protein 4", "gene_name": "Kank4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKIDGKDQSSQGDEEKEPPKSYPYSVETPYGFHLDLDFLKYVDDIEKGHTIKRIPIHRRAKQAKFSTLPRNFSLPNSGDRTYAVPPQQNWSPVVPRKISLGTQEPSQPLPLGDLPQASVQGSELNYHRKALLAKDARQAEAGSLEDVGSGRPQLLRASSMPATLLQNQVPEEPSLTSGPSTLLALPLLQDEGSVCDGAFDPAEGLMGFQASAQSVDRELGELEPAIPEQVWEGAEPEEGDLKASSHLSQPGPSSAVQSVPMDLEEVEIEHHMREAELVLTPGSATPSPPPLPSPILENDLSLDEIELSISEIPPPPPIEVDVRSIGIRVTEESLGLLETDTSSISSLKNQVLALEDKLSGRTEELARVRAALEQQEEETKAREQRIQELECTVAHLEEKLSQERASEAPDRTDATVNTDPLQELTPRESHDKNIGVNLLNTPDPECRAPRAEKNGFPWVQNNHKQSYPSPEEPVLPPQLSLPRGPEQILASSLCSCLSMELRIEEEGSEQEGGQEEGAGGLSRAAGESSWSTRESAPVIREEATSELPGAERPGRPASSPQDATIGQYVKKIQELLHEQWNCLEHGYPELASAIKQPASKLSSIQNQLLSSLNLLLSAYSAQAPEPEPKETPAPPPSTPPPPPPPPPEISPSTSLKSIMKKKDYGFRAGGNGTKKNLQFVGVNGGYETTSSEETSGEDSSPEDLSDSETEKKQDCSESREDRDLHPSCEAGQGVPEGTRNSGHTSDRGEEVSHLRAERYKPSEEFLNACQTLSQHLPETGDTTKQLLRQSLNTISQEWFRVSSRKLSSPEAVAAYLLEVQPHSPYLLKLLVNLADRSGNTALHYSVSHSNFAIVKLLLDTGVCNVDHQNKAGYTAVMITPLASAETKEDMAVVWKLLREGNVNIQATQGGQTALMLGVSHDREDMVQALLSCQADVNLQDNDGSSALMLACHQGNADLVRLLLAHPACNSSLTDKAGRTALSLVLNSPAHVEIAELLRAHSEPGRSLGPKELQKN", "length": 1016 }, "evidence": [ { "id": "A0A8V0ZP92", "url": "https://omabrowser.org/oma/group/A0A8V0ZP92/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of actin filament polymerization", "id": "GO:0030837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030837", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZP92", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 848, "end_pos": 850, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 180, "end_pos": 182 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 665, "end_pos": 667 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 78, "end_pos": 80 }, { "start_pos": 848, "end_pos": 850 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZR44-1", "uniprot_ac": "A0A8V0ZR44", "uniprot_id": "A0A8V0ZR44_CHICK", "mass": { "chemical_mass": 342096.0, "monoisotopic_mass": 342096.0 }, "refseq": { "ac": "XP_040562431", "name": "dmX-like protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562431" }, "gene_names": [ { "name": "DMXL2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44" } ] }, { "name": "DMXL2", "type": "synonym", "evidence": [ { "id": "XP_040562431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562431" } ] } ], "protein_names": [ { "name": "Dmx like 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44/entry#names_and_taxonomy" } ] }, { "name": "dmX-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040562431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562431" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040562431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562431" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DMXL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44", "locus": { "chromosome": "10", "start_pos": 9288355, "end_pos": 9338706, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022637", "url": "https://www.ensembl.org/id/ENSGALG00010022637" } ] } } ], "crossref": [ { "id": "415594", "url": "https://www.ncbi.nlm.nih.gov/gene/415594", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052208", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415594", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415594", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AENGNTC", "url": "https://omabrowser.org/oma/group/AENGNTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZP96", "url": "https://www.orthodb.org/?gene=A0A8V0ZP96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPA2", "url": "https://www.orthodb.org/?gene=A0A8V0ZPA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR44", "url": "https://www.orthodb.org/?gene=A0A8V0ZR44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13950:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13950:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040562431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040562431", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP96", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZP96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZP96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVEDIPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSQQQGRIAASYGNAVCIFEPLGINSHKRNSQLKCQWLKTGQFFLSSMTYNLAWDPQGNRLLTATDYLQLWAPPSSDILEEDEDDPDNPMKDDKVLPVLNDWKCVWQCKTAVSVHLMAWSPDGEYFATAGKDDCLLKVWYPITGWKSSLLPQENEEKKKCSGVANFSFAYLAHPRAVTGFSWRNISKYMPRGLVCNVLLTSCLDGICRLWAETLLPEDTLLGEQICETSTSSISSTISQSGKHKDRIQHALETIHHLKNMRKGQRRSSVLVTHTDVLPDQQGTHEVQRHISHHANALGHFHIAASINPNTDIPSVLAGTAFNIDESNGGFVVHWLNNKEFNFTSSIEVFMQHLRKLSEQQLEEDFDDVEVEEKEEIEEKERGLRMKLDHDLSIDRESETGTGTGSSERDDGEREGSPKTSLRGSLRMPLPTVLLDRKIELLLTEWNRNPDMLFTIHPVDGTFLLWHVKYLDEYTPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACPVLLKDTSNAVHQKTMDFLDKTLENRGPGFAQSSTNMNIISPIVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDTSHSSDRINRVMDPSKHLKGSSRQQLKNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITNKCGSNTQLLHVFQEDFILGYKPQKEDVEEKETEIFFQPSQGYRPPPFSEKFYLVVIEKDSTGCSVLQMWHLHLKSVQACLAKPTETTLSENKLSIPEQKTADSSPDLSPGVSPIPRSSSIANLQTASKLILSSRLVYSQPLDLPVGVEVIRATPSAGHLSSSSIYPVCLAPYLIVTSCSDNRVRFWRCTVETDLNSKNEERETYHWRKWPLMNDEGEDNSSTVTIVGRPVAVSCSYTGRLAVAYKQPVQHNGYVSKEFSMHVCILECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDACLNKDKYLVPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTDQTSSKEGVAVITLPLGGSIKQGIKSKWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHTVKFGDGESDVFTSEDLATQDSLKTSLIAKKTSVIDGAGIVDDVFGTPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVKDTEAGEGSGPKRHLSRTISVSGSTAKDTITAGKDGTRDYTEIDSIPPLPLYALLAADQDATYVSEETSKIPQGSEEDAKKKTEDQYSDLFQIQPVTTDDFIDFEPEKRESKSKVINLSQYGPTYFGREHASVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKNYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGLSTCHFAWAFHSEAEEELINMIPAIQKGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLAMKKKAVVWGLFRSQHDEKMTAFFSHNFSEDRWRKAALKNAFALLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESEFETSVTYTSILYEKILGCQKDGTGFSCTKLHSDPFLRSIAYWIMKDYTRALDTLLEQTPKDDDENPVIVKSCNPVVFSFYNYLRTHPLLIRRYFSSPEGTLATLGLKTEKSFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVRKKSAVATEKDASSPPMQAGVSDSKAGSGDIDWSKPISASFALEDTAESSAQFDWSQPAVKFDDEPLTLDWGEDKNESDEEDKDVGIIMKNSKSTSKSEEQDKTPDANVPQTPHGEISDVGDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAAMHEICNHESGGKDYCKTYAKVNGDLLDHESVMDKPDIGSYERHQIERRRLQAKREHAERRKWWLQKNQALLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKSPPHPNIEDVKVYTLHSLAASLSASIYQALCDSHSYSSQTEANQFTGMVYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSCNELFRLAAHPLNSRMWAAVFGGGVKLLVKPRRQSENIPAPPLPSEEMDKHRRRFNMRMLVPGRPVKDSTVPPPVPAERPSYKEKFIPPELSMWDYFMAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDIQIQEHKDANSYSWALLHLTMVKLVLHNVKNFFPIAGLEFNDLPVTSPLGIAVIKNLEHWEQILQDRMDQFEGPPPNYINTYPSDPGVGAGPAILRNKAMIEPENTPFKSKDYSALPAKRLWHFLVKQELLQETFIRYIFTKKRKQSESVEDRVEQVKQNCVAEDHKTKVEADLGYPGGKAKVIHKESDMIMAFAVNKANSNEIVLASTHDVQELDISALLAAQSFIWIGEEYDRESKSSDDIDFRGSTTTLTQSAAPSFGVSQIQPSSSMPWLGSGQTSTGAGVLIKRNLNNVKRMASHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFQQAGNARVTRMYFNSQGNKCGVADGEGFLSIWQVNQTTSNPKPYLSWQCHSKTTSDFAFITSSSLVATSGQSNDNRNVCLWDTLVSSGNSLVHAFTCHDHGATVLQYAPKHQLLISGGRKGYICIFDIRQRQILYTFQAHDSAIKALALDPSEDYFVTGSAEGNMKVWRLTGYNLIHSFKNEHAKQSIFRNIGAGVTQIETIQGNRIFSCGADGTLKMRVLPNAFNIPSGIFDIL", "length": 3067, "header": "tr|A0A8V0ZR44-1|A0A8V0ZR44_CHICK Isoform 1 of Dmx like 2 OS=Gallus gallus OX=9031 GN=DMXL2 PE=4 SV=1 CANONICAL=A0A8V0ZR44-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZP96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44/entry#A0A8V0ZP96-1", "sequence": { "sequence": "MVNTLQQLGRGLVCNVLLTSCLDGICRLWAETLLPEDTLLGEQICETSTSSISSTISQSGKHKDRIQHALETIHHLKNMRKGQRRSSVLVTHTDVLPDQQGTHEVQRHISHHANALGHFHIAASINPNTDIPSVLAGTAFNIDESNGGFVVHWLNNKEFNFTSSIEVFMQHLRKLSEQQLEEDFDDVEVEEKEEIEEKERGLRMKLDHDLSIDRESETGTGTGSSERDDGEREGSPKTSLRGSLRMPLPTVLLDRKIELLLTEWNRNPDMLFTIHPVDGTFLLWHVKYLDEYTPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACPVLLKDTSNAVHQKTMDFLDKTLENRGPGFAQSSTNMNIISPIVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDTSHSSDRINRVMDPSKHLKGSSRQQLKNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITNKCGSNTQLLHVFQEDFILGYKPQKEDVEEKETEIFFQPSQGYRPPPFSEKFYLVVIEKDSTGCSVLQMWHLHLKSVQACLAKPTETTLSENKLSIPEQKTADSSPDLSPGVSPIPRSSSIANLQTASKLILSSRLVYSQPLDLPVGVEVIRATPSAGHLSSSSIYPVCLAPYLIVTSCSDNRVRFWRCTVETDLNSKNEERETYHWRKWPLMNDEGEDNSSTVTIVGRPVAVSCSYTGRLAVAYKQPVQHNGYVSKEFSMHVCILECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDACLNKDKYLVPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTDQTSSKEGVAVITLPLGGSIKQGIKSKWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHTVKFGDGESDVFTSEDLATQDSLKTSLIAKKTSVIDGAGIVDDVFGTPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVKDTEAGEGSGPKRHLSRTISVSGSTAKDTITAGKDGTRDYTEIDSIPPLPLYALLAADQDATYVSEETSKIPQGSEEDAKKKTEDQYSDLFQIQPVTTDDFIDFEPEKRESKSKVINLSQYGPTYFGREHASVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKNYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGLSTCHFAWAFHSEAEEELINMIPAIQKGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLAMKKKAVVWGLFRSQHDEKMTAFFSHNFSEDRWRKAALKNAFALLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESEFETSVTYTSILYEKILGCQKDGTGFSCTKLHSDPFLRSIAYWIMKDYTRALDTLLEQTPKDDDENPVIVKSCNPVVFSFYNYLRTHPLLIRRYFSSPEGTLATLGLKTEKSFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVRKKSAVATEKDASSPPMQAGVSDSKAGSGDIDWSKPISASFALEDTAESSAQFDWSQPAVKFDDEPLTLDWGEDKNESDEEDKDVGIIMKNSKSTSKSEEQDKTPDANVPQTPHGEISDVGDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAAMHEICNHESGGKDYCKTYAKVNGDLLDHESVMDKPDIGSYERHQIERRRLQAKREHAERRKWWLQKNQALLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKSPPHPNIEDVKVYTLHSLAASLSASIYQALCDSHSYSSQTEANQFTGMVYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSCNELFRLAAHPLNSRMWAAVFGGGVKLLVKPRRQSENIPAPPLPSEEMDKHRRRFNMRMLVPGRPVKDSTVPPPVPAERPSYKEKFIPPELSMWDYFMAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDIQIQEHKDANSYSWALLHLTMVKLVLHNVKNFFPIAGLEFNDLPVTSPLGIAVIKNLEHWEQILQDRMDQFEGPPPNYINTYPSDPGVGAGPAILRNKAMIEPENTPFKSKDYSALPAKRLWHFLVKQELLQETFIRYIFTKKRKQSESVEDRVEQVKQNCVAEDHKTKVEADLGYPGGKAKVIHKESDMIMAFAVNKANSNEIVLASTHDVQELDISALLAAQSFIWIGEEYDRESKSSDDIDFRGSTTTLTQSAAPSFGVSQIQPSSSMPWLGSGQTSTGAGVLIKRNLNNVKRMASHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFQQAGNARVTRMYFNSQGNKCGVADGEGFLSIWQVNQTTSNPKPYLSWQCHSKTTSDFAFITSSSLVATSGQSNDNRNVCLWDTLVSSGNSLVHAFTCHDHGATVLQYAPKHQLLISGGRKGYICIFDIRQRQILYTFQAHDSAIKALALDPSEDYFVTGSAEGNMKVWRLTGYNLIHSFKNEHAKQSIFRNIGAGVTQIETIQGNRIFSCGADGTLKMRVLPNAFNIPSGIFDIL", "length": 2822, "header": "tr|A0A8V0ZP96-1|A0A8V0ZR44_CHICK Computationally mapped isoform of Dmx like 2 OS=Gallus gallus OX=9031 GN=DMXL2 PE=4 SV=1 CANONICAL=A0A8V0ZR44-1" }, "locus": { "chromosome": "10", "start_pos": 9328028, "end_pos": 9289608, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055076.1", "url": "https://www.ensembl.org/id/ENSGALT00010055076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033303.1", "url": "https://www.ensembl.org/id/ENSGALP00010033303.1" } ] } }, { "isoform_ac": "A0A8V0ZPA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44/entry#A0A8V0ZPA2-1", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVEDIPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSQQQGRIAASYGNAVCIFEPLGINSHKRNSQLKCQWLKTGQFFLSSMTYNLAWDPQGNRLLTATDYLQLWAPPSSDILEEDEDDPDNPMKDDKVLPVLNDWKCVWQCKTAVSVHLMAWSPDGEYFATAGKDDCLLKVWYPITGWKSSLLPQENEEKKKCSGVANFSFAYLAHPRAVTGFSWRNISKYMPRGLVCNVLLTSCLDGICRLWAETLLPEDTLLGEQICETSTSSISSTISQSGKHKDRIQHALETIHHLKNMRKGQRRSSVLVTHTDVLPDQQGTHEVQRHISHHANALGHFHIAASINPNTDIPSVLAGTAFNIDESNGGFVVHWLNNKEFNFTSSIEVFMQHLRKLSEQQLEEDFDDVEVEEKEEIEEKERGLRMKLDHDLSIDRESETGTGTGSSERDDGEREGSPKTSLRGSLRMPLPTVLLDRKIELLLTEWNRNPDMLFTIHPVDGTFLLWHVKYLDEYTPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACPVLLKDTSNAVHQKTMDFLDKTLENRGPGFAQSSTNMNIISPIVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDTSHSSDRINRVMDPSKHLKGSSRQQLKNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITNKCGSNTQLLHVFQEDFILGYKPQKEDVEEKETEIFFQPSQGYRPPPFSEKFYLVVIEKDSTGCSVLQMWHLHLKSVQACLAKPTETTLSENKLSIPEQKTADSSPDLSPGVSPIPRSSSIANLQTASKLILSSRLVYSQPLDLPVGVEVIRATPSAGHLSSSSIYPVCLAPYLIVTSCSDNRVRFWRCTVETDLNSKNEERETYHWRKWPLMNDEGEDNSSTVTIVGRPVAVSCSYTGRLAVAYKQPVQHNGYVSKEFSMHVCILECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDACLNKDKYLVPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTDQTSSKEGVAVITLPLGGSIKQGIKSKWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHTVKFGDGESDVFTSEDLATQDSLKTSLIAKKTSVIDGAGIVDDVFGTPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVKDTEAGEGSGPKRHLSRTISVSGSTAKDTITAGKDGTRDYTEIDSIPPLPLYALLAADQDATYVSEETSKIPQGSEEDAKKKTEDQYSDLFQIQPVTTDDFIDFEPEKRESKSKVINLSQYGPTYFGREHASVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKNYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGLSTCHFAWAFHSEAEEELINMIPAIQKGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLAMKKKAVVWGLFRSQHDEKMTAFFSHNFSEDRWRKAALKNAFALLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESEFETSVTYTSILYEKILGCQKDGTGFSCTKLHSDPFLRSIAYWIMKDYTRALDTLLEQTPKDDDENPVIVKSCNPVVFSFYNYLRTHPLLIRRYFSSPEGTLATLGLKTEKSFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVRKKSAVATEKDASSPPMQAGVSDSKAGSGDIDWSKPISASFALEDTAESSAQFDWSQPAVKFDDEPLTLDWGEDKNESDEEDKDVGIIMKNSKSTSKSEEQDKTPDANVPQTPHGEISDVGDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAAMHEICNHESGGKDYCKTYAKVNGDLLDHESVMDKPDIGSYERHQIERRRLQAKREHAERRKWWLQKNQALLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKSPPHPNIEDVKVYTLHSLAASLSASIYQALCDSHSYSSQTEANQFTGMVYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSCNELFRLAAHPLNSRMWAAVFGGGVKLLVKPRRQSENIPAPPLPSEEMDKHRRRFNMRMLVPGRPVKDSTVPPPVPAERPSYKEKFIPPELSMWDYFMAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDIQIQEHKDANSYSWALLHLTMVKLVLHNVKNFFPIAGLEFNDLPVTSPLGIAVIKNLEHWEQILQDRMDQFEGPPPNYINTYPSDPGVGAGPAILRNKAMIEPENTPFKSKDYSALPAKRLWHFLVKQELLQETFIRYIFTKKRKQSEVEADLGYPGGKAKVIHKESDMIMAFAVNKANSNEIVLASTHDVQELDISALLAAQSFIWIGEEYDRESKSSDDIDFRGSTTTLTQSAAPSFGVSQIQPSSSMPWLGSGQTSTGAGVLIKRNLNNVKRMASHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFQQAGNARVTRMYFNSQGNKCGVADGEGFLSIWQVNQTTSNPKPYLSWQCHSKTTSDFAFITSSSLVATSGQSNDNRNVCLWDTLVSSGNSLVHAFTCHDHGATVLQYAPKHQLLISGGRKGYICIFDIRQRQILYTFQAHDSAIKALALDPSEDYFVTGSAEGNMKVWRLTGYNLIHSFKNEHAKQSIFRNIGAGVTQIETIQGNRIFSCGADGTLKMRVLPNAFNIPSGIFDIL", "length": 3046, "header": "tr|A0A8V0ZPA2-1|A0A8V0ZPA2_CHICK Computationally mapped isoform of Dmx like 2 OS=Gallus gallus OX=9031 GN=DMXL2 PE=4 SV=1 CANONICAL=A0A8V0ZR44-1" }, "locus": { "chromosome": "10", "start_pos": 9338583, "end_pos": 9289608, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055083.1", "url": "https://www.ensembl.org/id/ENSGALT00010055083.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033308.1", "url": "https://www.ensembl.org/id/ENSGALP00010033308.1" } ] } }, { "isoform_ac": "A0A8V0ZR44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44/entry#A0A8V0ZR44-1", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVEDIPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSQQQGRIAASYGNAVCIFEPLGINSHKRNSQLKCQWLKTGQFFLSSMTYNLAWDPQGNRLLTATDYLQLWAPPSSDILEEDEDDPDNPMKDDKVLPVLNDWKCVWQCKTAVSVHLMAWSPDGEYFATAGKDDCLLKVWYPITGWKSSLLPQENEEKKKCSGVANFSFAYLAHPRAVTGFSWRNISKYMPRGLVCNVLLTSCLDGICRLWAETLLPEDTLLGEQICETSTSSISSTISQSGKHKDRIQHALETIHHLKNMRKGQRRSSVLVTHTDVLPDQQGTHEVQRHISHHANALGHFHIAASINPNTDIPSVLAGTAFNIDESNGGFVVHWLNNKEFNFTSSIEVFMQHLRKLSEQQLEEDFDDVEVEEKEEIEEKERGLRMKLDHDLSIDRESETGTGTGSSERDDGEREGSPKTSLRGSLRMPLPTVLLDRKIELLLTEWNRNPDMLFTIHPVDGTFLLWHVKYLDEYTPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACPVLLKDTSNAVHQKTMDFLDKTLENRGPGFAQSSTNMNIISPIVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDTSHSSDRINRVMDPSKHLKGSSRQQLKNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITNKCGSNTQLLHVFQEDFILGYKPQKEDVEEKETEIFFQPSQGYRPPPFSEKFYLVVIEKDSTGCSVLQMWHLHLKSVQACLAKPTETTLSENKLSIPEQKTADSSPDLSPGVSPIPRSSSIANLQTASKLILSSRLVYSQPLDLPVGVEVIRATPSAGHLSSSSIYPVCLAPYLIVTSCSDNRVRFWRCTVETDLNSKNEERETYHWRKWPLMNDEGEDNSSTVTIVGRPVAVSCSYTGRLAVAYKQPVQHNGYVSKEFSMHVCILECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDACLNKDKYLVPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTDQTSSKEGVAVITLPLGGSIKQGIKSKWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHTVKFGDGESDVFTSEDLATQDSLKTSLIAKKTSVIDGAGIVDDVFGTPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVKDTEAGEGSGPKRHLSRTISVSGSTAKDTITAGKDGTRDYTEIDSIPPLPLYALLAADQDATYVSEETSKIPQGSEEDAKKKTEDQYSDLFQIQPVTTDDFIDFEPEKRESKSKVINLSQYGPTYFGREHASVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKNYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGLSTCHFAWAFHSEAEEELINMIPAIQKGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLAMKKKAVVWGLFRSQHDEKMTAFFSHNFSEDRWRKAALKNAFALLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESEFETSVTYTSILYEKILGCQKDGTGFSCTKLHSDPFLRSIAYWIMKDYTRALDTLLEQTPKDDDENPVIVKSCNPVVFSFYNYLRTHPLLIRRYFSSPEGTLATLGLKTEKSFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVRKKSAVATEKDASSPPMQAGVSDSKAGSGDIDWSKPISASFALEDTAESSAQFDWSQPAVKFDDEPLTLDWGEDKNESDEEDKDVGIIMKNSKSTSKSEEQDKTPDANVPQTPHGEISDVGDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAAMHEICNHESGGKDYCKTYAKVNGDLLDHESVMDKPDIGSYERHQIERRRLQAKREHAERRKWWLQKNQALLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKSPPHPNIEDVKVYTLHSLAASLSASIYQALCDSHSYSSQTEANQFTGMVYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSCNELFRLAAHPLNSRMWAAVFGGGVKLLVKPRRQSENIPAPPLPSEEMDKHRRRFNMRMLVPGRPVKDSTVPPPVPAERPSYKEKFIPPELSMWDYFMAKPFLPLSDSGVIYDSDESIHSDEEEDDAFLSDIQIQEHKDANSYSWALLHLTMVKLVLHNVKNFFPIAGLEFNDLPVTSPLGIAVIKNLEHWEQILQDRMDQFEGPPPNYINTYPSDPGVGAGPAILRNKAMIEPENTPFKSKDYSALPAKRLWHFLVKQELLQETFIRYIFTKKRKQSESVEDRVEQVKQNCVAEDHKTKVEADLGYPGGKAKVIHKESDMIMAFAVNKANSNEIVLASTHDVQELDISALLAAQSFIWIGEEYDRESKSSDDIDFRGSTTTLTQSAAPSFGVSQIQPSSSMPWLGSGQTSTGAGVLIKRNLNNVKRMASHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFQQAGNARVTRMYFNSQGNKCGVADGEGFLSIWQVNQTTSNPKPYLSWQCHSKTTSDFAFITSSSLVATSGQSNDNRNVCLWDTLVSSGNSLVHAFTCHDHGATVLQYAPKHQLLISGGRKGYICIFDIRQRQILYTFQAHDSAIKALALDPSEDYFVTGSAEGNMKVWRLTGYNLIHSFKNEHAKQSIFRNIGAGVTQIETIQGNRIFSCGADGTLKMRVLPNAFNIPSGIFDIL", "length": 3067, "header": "tr|A0A8V0ZR44-1|A0A8V0ZR44_CHICK Isoform 1 of Dmx like 2 OS=Gallus gallus OX=9031 GN=DMXL2 PE=4 SV=1 CANONICAL=A0A8V0ZR44-1" }, "locus": { "chromosome": "10", "start_pos": 9338583, "end_pos": 9289608, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055080.1", "url": "https://www.ensembl.org/id/ENSGALT00010055080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033305.1", "url": "https://www.ensembl.org/id/ENSGALP00010033305.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1251, "start_aa": "Thr", "end_pos": 1251, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1251", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415594", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415594", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M0S3-1", "protein_name": "Dmx like 2", "gene_name": "DMXL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVEDVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSLQLWAPPGGDILEEEEEINNKILPVLNDWKCIWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQASTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSVSSNLTHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELKPDQTTTHEVQRHISHHANALCHFHIAASINPATDIPNVFVGTVFNIDDGNGGFVVHWLNNKEFHFTSSTEIFMQQLRKLSERQVDHESDEGNKEDEERSQEERERGLHMKLDHELSLDRESEAGTGSSEHEDAEREGSPRTYARPIISMPLPTVLLDRKIEMLLAEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVKVSFSSRIPVAFPSGDASSLSKNIMMYACINAVKDSHHTPLHQDMLAECSPHGSLTHSGSHSTNMNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDFQWASDSKLSRLIDPVRHIKGSLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITNQCGSNTQLLHVFQEDFIRGYKPHKEDMEKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNCSILHMWHLHLKSIQACLAKTSEGVSSESLLSVPGQKHVDSSPETSPSMSPMSHSSSIANLQTASKLILSSRLVYSQPLDLPVGVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMETNLQCKSDEKETYHWRRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDELLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTEQTNSKDGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVRFGDVHTDSFEAEETAIQDHSAFKSSMLSRKSIAEGTAIADDVFCSPTVVQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDADAGEGTKRHLSRTISVSGSTAKDTVTIGKDGTRDYTEIDSIPPLPLYALLAADQDTTYRVSEESTKVPQSCEDHAESQPEDQYSELFQIQDITTDDIDLEPEKRDNKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKSYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKAAFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESDFETSSTYLSILNQKILGCQKDGSGFDCERLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEHQVIIKSCNPVVFSFYNYLRTHPLLIRRNLVSPEGTLATVGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKVSALPSKKDQRDFISKKMDGVPSESKTLSDSDRSFGTDWSNVTSSQIDWSQPVVRIEEEPLTLDWGEEHDSALEEEEEDAVGLVMKSTDIGKKDRQEDQKTPDPNVLLTPQEEDHLEGDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYASKMYSKGESDLLDQEEKVDKPDIGSYERHQIERRRLQAKREHAERRKSWLHKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNILLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPQRQSENISAPPVPSEDIDKHRRRFNMRMLVPGRPVKDTTPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESIHSDEEEDDAFFSDIQIQEHQDPNSYSWALLHLTMVKLALHNVRNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDHFEGPPPNYINTYPTDLSVGAGPASLRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFMRYIFTKKRKQSEVEADLGYPGGKAKIIHKESDMIMAFSINKANCNEIVLASTHDVQELDITSLLACQSYIWIGEEYDRESKSSDDIDYRGSTTTLYQPTAASYSASQVHPSSSLPWLGSGQTSTGAGVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLICFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYVSWQCHSKATSDFAFVTSSSLVATSGHSNDNRNVCLWDTLITPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLMHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTGHGLIHSFKNEHAKQSIFRNLGAGVMQINITQGNRIFSCGADGTLKTRVLPSAFNIPHRILDIL", "length": 3036 }, "evidence": [ { "id": "A0A8V0ZR44", "url": "https://omabrowser.org/oma/group/A0A8V0ZR44/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I5ZMW1-1", "protein_name": "Dmx-like 2", "gene_name": "Dmxl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGEVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRVAASYGNAVCIFEPLGINSHKRNSQLKCQWLKTGQFFLSSVTFNLAWDPQDNRLLTATDSIQLWAPPGSDILEEEEEVDNKVPPVLNDWKCIWQCKTSVSIHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDPHEVKRRRASTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSVASNLSSAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDKTATHEVHRHISHHANALCHFHIAASINPATDIPNVLVGTAFNIDDINGGFVVHWLNNKEFHFTSSTEIFMHQLRKLSEKQLDHESDDADREDDERSQEERERGLRMKLDHELSLDRESEAGTGSSEHEDGEREGSPRTHPRPSVSLPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDANSLSKNIMMYACVNATKDSYSTTSQPELMSVDSSHGSQPHYTSHSTDWNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPEADCQWDTDSKLNRLIDPVKHTKGSSKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPEASKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKEKETEIFFQPSQGYRPPPFSEKFFLVVIEKDGNNNSILHMWHLHLQSVQACLAKAAEGISSDSLLSVPGQKNMESSSETSSSVSSMPHSSSIANLQTASKLILSSRLVYSQPLDLPEAVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMETNSPCSSSGENETYHWRRWPLMNDEEKDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPIHHNGFISKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDAFLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVNDQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHSVKFGDVEADSPVEQTIIQDHSAFKSSMLTRKSIAEGAAIPDDVFCSPTVVQDGGLFEAAHALSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDPDAGEGTKRHLSRTISVSGSTAKDTVTIGKDGTRDYTEIDSIPPLPLHALLAADQDTSYRISEDSAKKPQSYEDHIESQPEDQYSELFQVQEITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKNYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNVNTLRRCIEKVAKAAFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLFESEFETSSTYISILNQKILGCQKDGTGFNCKRLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVIIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNIADKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKISSLNAKKDQLDFVSERMENGPSESKPVSSSDGGSGADWLAVTSSQFDWSQPIVTVDEEPLRLDWGEDHDGALEEDDGGGLVMKAADAKKAGQDQRASDPSALLTPQEEDCAEGDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKAYSKVESELLDHEEMVDKPDIGSYERHQIERRRLQAKREHAERRKLWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMRTPPQPSVEDVKVHTLHSLAASLSASIYQALCDSHSYSSQTDGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSAPAQWPGVSSLINLLSSAQDEDQPRLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSESIAAPPVASEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESVHSDDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNIKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDHFEGPPPNYVNTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEADLGYPGGKAKVIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDIDYRGSTTTLYQPGAASHSSSQVHPPPSLPWLGSGQTSTGATVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGQSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLMHTFQAHDSAIKALALDSCEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIEISQDNRLFSCGADGTLKTRVLPSAFNIPNRILDIL", "length": 3035 }, "evidence": [ { "id": "A0A8V0ZR44", "url": "https://omabrowser.org/oma/group/A0A8V0ZR44/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BPN8-1", "protein_name": "DmX-like protein 2", "gene_name": "Dmxl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRVAASYGNAVCIFEPLGVNSHKRNSQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGGDILEEEEDVDNRAPPVLNDWKCIWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDPHEVKRRRASTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSVASNLSSAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDKTATHEVHRHISHHANALCHFHIAASINPTTDIPNVLVGTAFNIDDINGGFVVHWLNNKEFHFTSSTEIFMHQLRKLSEKQLDHESDDADREDEERSQDERERGLRMKLDHELSLDRESEAGTGSSEHEDGEREGSPRTHPRPSISMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDANSLSKNIMMYACVNATKDSYNPSQQEMMSVDSPHGSQLHSPSHSTDMNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDCQWDSDSKVNRLIDPVKHTKASSKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPEASKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKEKESEIFFQPSQGYRPPPFSEKFFLVVIEKDGNNNSILHMWHLHLKSVQACLAKAAEGISSDSLLSVPGQKNLDSSPETSSSMSSVPHSSSIANLQTASKLILSSRLVYSQPLDLPEAVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMETNSLGNTSDESETYHWRRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPIHHNGFISKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDAFLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVSDQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHSVKFGNVDADSPVEETIQDHSALKSSMLARKSIVEGAAIPDDVFCSPTVVQDGGLFEAAHALSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDPDAGEGTKRHLSRTISVSGSTAKDTVTIGKDGTRDYTEIDSIPPLPLHALLAADQDTSYRISEDSTKKPQSYEDHIESQSEDQYSELFQVQEITTDDIDLEPEKRENKSKVINLSQYGPACFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKNYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNVNTLRRCIEKVAKAAFQRNNEALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLFESEFETSSTYISILNQKILGCQKDGTGFDCKRLHPDPFLRSLAYWVVKDYTRALDTLLEQTPKEDDEQQVIIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNIADKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKISSLTAKKDQLDSVSGRMENGPSESKPVSRSDGGSGADWSAVTSSQFDWSQPMVTVDEEPLRLDWGDDHDGALEEDDGGGLVMKTTDAKKAGQEQSASDPRALLTPQDEECADGDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKAHSTVETERLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKLWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPSVEDVKVHTLHSLAASLSASIYQALCDSHSYSQSEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSAPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSESIAAPPVASEDMDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESVHSDDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNIKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDHFEGPPPNYVNTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDSSALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEADLGYPGGKAKVIHKESDMIMAFSINKANCNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDIDYRGSTTTLYQPGAASHSSSQPHPPPSLPWLGSGQTSTGATVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLIHTFQAHDSAIKALALDSCEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIAISQDNRLFSCGADGTLKTRVLPSAFNIPNRILDIL", "length": 3032 }, "evidence": [ { "id": "A0A8V0ZR44", "url": "https://omabrowser.org/oma/group/A0A8V0ZR44/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TDJ6-1", "protein_name": "DmX-like protein 2", "gene_name": "DMXL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQVSCVECSNQQGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDSIQLWAPPGDDILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQSSTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSIASSLSHAGRHKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTAFNVDDGNGGFVVHWLNNKEFHFTSSTEVFMHQLRKLSDKQVDHENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPRTYSRLSVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDASSLSKNIMMYACINATKDSHHTLLHQEGMSVGSPHGSQPHSRSHSTHMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAITNQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNNSILHMWHLHLKSVQACLAKASEGASSESLLSVPGQKNVDSSPETSPSVSPMPHSSSIANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMEANPECNKSDEKEIYHWKRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTEQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVKFGDTEADSSNAEEAAMQDHSTFKSNMLARKSVVEGTAISDDVFCSPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDPDAGEGTKRHLSRTISVSGSTAKETVTVGKDGTRDYTEIDSIPPLPLYALLAADQDTSYRISEESTKIPQSYEDQTVSQPEDQYSELFQIQDIPTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDESRDKSCSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESEFETSSTYISILNQKILGCQKDGSGFSCKRLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEHQVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKTSALSAKKDQPDFISHRMDDVPSHSKALSDGNGSSGIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGEDHDSALDEEEDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVESDLLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNILLCEAVVAVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSENISAPPVLSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLSDSGVIYDSDESIHSDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEADLGYPGGKAKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDVDYRGSTTTLYQPSATSYSASQVHPPSSLPWLGTGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGADGTLKTRVLPNAFNIPNRILDIL", "length": 3036 }, "evidence": [ { "id": "A0A8V0ZR44", "url": "https://omabrowser.org/oma/group/A0A8V0ZR44/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W425-1", "protein_name": "Rabconnectin-3A", "gene_name": "Rbcn-3A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNCHQILSGACNAGDRCFAIGSVEGIPFTAYAAGCNVVILASTFERVQIIPGANHGYVKISALDCSTDTGKIAAAYENKICIFEPTPVIESSKHNTHFLDYRWVQTGSFTSHSNVVTLSWNLEGTRLLTGGTNIQLWKSKSPTHQQEEEHTGVKFEIGESKEPKQTSNAQSEDVSTWENIWSCQTAIPIYHMAFSPDGTLFATCGRNDRLVKIWYENKQVLFPAKGSSNAGPTPSCRHGVDDGTTSSSGGELNFTYVYIAHPRAVSNIVWRKTSKYMPKGSVANMLVTSCLDNICRIWIETVLPDDGMVNMTQFDPMASQNPKFRTHRHKHRFMQRLKHMKTCFHIRRHMKAGASAVPGAASAGAASGGGTAGAMGGMGSSPASYTNYLGPIPSLPSSCSVHDFHSYGFQGSGVTPGMHFHLAASINAETDIPLVPSMQTSDPANQNVFILHWLNNKEMHFTLQAEAILQELTKKVIDEENGHGNASSGGVDLPDDAHGSHSQAHAHKKYLRSSKSVSVDDSGEEFSRYSQHTAGTGMGGGGGGAGLHLNSMSNTTSQNSLNNEPAHPITQLVDSLDNKIECLLRDWHQSPDLLFAIHPVDGSYLIWVIEWLDDYYPGSFRQAQVSFSTRIPSAFPLGDAMSMSTTVSLFNTGTHPLAFRDIANNVRSKDEFHKGHADDSSLKSDQHSGQTFERHDEEQEDAADDDGDGDREGDADQDEGGGDRSAAASGGGAAEHSSSSQDSAATGASALPLNVSPSVSMVTKHSNGTLNLWQLTFAFKTKFTQVLSIGHVSRASGHRFRVNDITCHPVLPLLVSTSHHNLPDSEAKSPMSLFEQPLSGGLPSGGGTGAGPSVGSNGDKDVFTPTGFCSELILWRVDSVGPLCHSGGVSELARINSPEISAFSNVAWIPTLLPSTTLGSYSNSPSACFVASDGENLRVYQAVIDARTLLAEISCSENLNTLHKSHSLSSMISNASSTMRAQRSALHDKLKVVSQQSTARPGCILQLDAISDAKHDWQNTQFLHVFQAQLITGGQRTPQADPHDLEEPRLNALLESDMDAIVDLQRNADFEEPFYIVNIEKTLRGSTIHMWRIVISSKQQSSFLSETAMYVPDSNLTQEPDEDGAGGNPNPRRMSQGAETLTGAEHFGPQVEAPHISITTKKVCTQELPLPEGVDVIHASPAAGHLSSSSIYPACFAPYIIVTACSDSISRFWKCEPIGDEDDPNPEGDAYHWSEWKMFSRIQHSAIEIPGQPLNISAAYSGRIACAYKYGKSFTRPNKGPDPDSRYVNLCVAIYECESSGGSEWVLEDTIHLKNVHLPRINIGHGIDLSYLHDSRLLAKKQRLNQVLHTFAHDPESRSPRSGETTPELAVNRQPSAAASGLLTVPSFSTLQSLRKSIAENGNTCPLTQKHLVQLDWVSKEDGSHILTVAVGSKILLYTPVSSDIAQANIKAMKESRSVNRPILRKASSLAQPNFVDEIRWMKLRQIDLQTADGLPPLPMQISWVRDGILVVAMDSEMHVYSQWKPHYSSHFAAAAAAAGEDVPDTRNLRDEDLRSLANESTQLRLKNVASMPLISKVSTANLQLLSHDKKRRLGNTSMANMNGAGGAGGTGTYGGGADDGGNDDYMTDFGLFQASRIACPVLPQYHPKQLMELLNCGKIRWVKAILAHLVRCMSGNSSSTVNQDDDGYARQRSWSRSRTLSISYTADQNIQAEHRGSTTQIPEELMLDYAEINSIPPLPLWVLLNADRETPGQSNNYAEGDKDYDELFDMHNSEDNLDELLSEGDEKKRQERRLSLPEKHSISHFGPRQGQLLSRLLTHTHLPGLSSLDQMHLLALADTVATCNTDFSDKFAADQGKSGGMAGGAGSGAVKDGSTSTDSLDDCGLRFLLAMKHFTYLLRCLPLQQRAQFQRQGVGTSNIVWAFHSESEEELLNLIPSYTKGDLRWATLRDLGVGYWLKNINTLRRCVEKLAKCAYQQKQEPLDAAIYYLAMKKKSLVWGLFRSRRDEKMTAFFGNNFAEDRWRKAALKNAFVLLGKQRFEHAVAFFLLANSLNDAIEVCMNKLEDFQLALIIARLYEGDGEGCYYHHLLHEHILGTDAATGRCDLSRAHPDPFLRSMTYWTIKKYQESLNTLLLNNVGSLHSSYREEDLLRPEQQATNPNVFNFYIYLRTHPLLIRQNIALSAQEKRIAHVVLSGFNYAGDAAPSAVACDKQLQLEDSITPIERQLYFTTAHGHFKSGCPALALEVLNKLPQKISDDSGGSVAGSQAQERAQQNKEELINTGIMDQWGATPAAASNTADAFDWGAPVSSEPEAKFEIKWDDEDEEEDPDLEPDEPELATPQPQAPILGRGKSNGNDTKMDIMAQQLKFVACLKILMEELSTLATGFEVDGGQLRYQLYMWLEREVEALKQLCNYCSQAEQSSHESGDADAEARDKEMNASIYPSTERPTLHEILMQDKQDFEAKVMRAAKRKRWLKANETLLRTLLSYCSLHGASGGGLASVRMELVLLLQELQQEKTQQQLLSPLPFPTTLPLLSACVAGNKTVIADPIKYLQSQTVDMLQSIIKVLPFPGIEPSALSEIFVLRDLAVALSSCIYQSLCDSESFVVNNSAFNGYPSPGMENIAKINSSFECSYLVGSRNAYGRRRKYSTDEPAGVCTTPSKWPGVTNLRALLAREKDEDVPKLNVLLLESFVSTYMALFIYSLSTCDSRLLYRLSGQSFNNETWSTLFGGGMKKLLIKPAAAPPPTQMVTGGAGAGGASGGTGSTSEEPTDENSVWNTVTSITKQRMKLNMKILGSFSQNSTSSNMKEDKPTYREQFMPPETSMLSYFLTKPPTTECDDYDTDDSHESDNEEEEEDDDDVNVSRSQLKAKDNTEHTNPTSYSWSILRLALIKISTHKIQELVKVAGIELQDLPVISPLSHEVLRTLNRWQDFALSDLIARGPPSRNYIPGCYAESGINGLAIHKYRSLLNKDNTPFVSGSSAGPIRRLWNYLVRQEPAQEVFIKSIFVKNMEPSTRGSHHTNNDNETDEGQSHSTNENTDHIRIIHKDHESILSFCLKNNSSSMIAFANPREIQEFDISLLLESPNWYEDECDYDMMNLSKDADTNSSSFLIIQTQEQNQFGSNSNAYSESNASTQSASQSGRGTSMVLRHKVDNVKRMSAHPLMPLYLTGGQDGSVQIWEWGHQQPVCSPRTSGTFAKVTRCRFSEQGNKFGIGDGDGKLSLWQAGIASQNNRSFISYQCHNKALSDFVFLGSCSLLASAGQSSENKNINIWDTLLPHKKSCVSAFTCHDQGSSCLVFAPQHQVLISCGKRGDVCVFDVRQRTLRHRYQAHDSTIKCIALDPHEEFFVTGSIEGDIKIWDMNQFMLINTFPHEHAKNGFFKHTGQGVSQVYVDAFGRLFSCGSDGCMKVRLLVEKDNIVHSVY", "length": 3426 }, "evidence": [ { "id": "A0A8V0ZR44", "url": "https://omabrowser.org/oma/group/A0A8V0ZR44/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "RAVE complex", "id": "GO:0043291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043291", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1504, "end_pos": 1506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1562, "end_pos": 1564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1705, "end_pos": 1707, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1994, "end_pos": 1996, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2321, "end_pos": 2323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2867, "end_pos": 2869, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZR44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR44" }, { "id": "PF12234", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RAVE complex protein Rav1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 1149, "end_pos": 1385, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1251 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1067, "end_pos": 1069 }, { "start_pos": 1504, "end_pos": 1506 }, { "start_pos": 1562, "end_pos": 1564 }, { "start_pos": 1705, "end_pos": 1707 }, { "start_pos": 1994, "end_pos": 1996 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 2321, "end_pos": 2323 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 2867, "end_pos": 2869 }, { "start_pos": 405, "end_pos": 407 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPA8-1", "uniprot_ac": "A0A8V0ZPA8", "uniprot_id": "A0A8V0ZPA8_CHICK", "mass": { "chemical_mass": 23915.0, "monoisotopic_mass": 23915.0 }, "refseq": {}, "gene_names": [ { "name": "C1orf210", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA8" } ] } ], "protein_names": [ { "name": "Type III endosome membrane protein TEMP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C1orf210", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA8", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZPA8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0ZPA8", "url": "https://www.orthodb.org/?gene=A0A8V0ZPA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31450:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31450:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZPA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLVCHPRSCGDRSSQLWSPGSWAAKKARGFLEMSAQHSRPQLQTTTVSWVRESHLPPVHPQGWPPHHEQHCEACMWSAVVEHLLCHSPALMGLSSAAATVPPVGKGGRSWPYLVGFLVAAISISILVALVAKCKLCHKNFTSYRHRPLPETGSIGGSPLEEGTGWDRGSSGWGDSENPPVSSVTGLHVEDDDGFIEDNYIQPSEQLPEEEERESHISI", "length": 219, "header": "tr|A0A8V0ZPA8-1|A0A8V0ZPA8_CHICK Isoform 1 of Type III endosome membrane protein TEMP OS=Gallus gallus OX=9031 GN=C1orf210 PE=4 SV=1 CANONICAL=A0A8V0ZPA8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPA8/entry#A0A8V0ZPA8-1", "sequence": { "sequence": "MSLVCHPRSCGDRSSQLWSPGSWAAKKARGFLEMSAQHSRPQLQTTTVSWVRESHLPPVHPQGWPPHHEQHCEACMWSAVVEHLLCHSPALMGLSSAAATVPPVGKGGRSWPYLVGFLVAAISISILVALVAKCKLCHKNFTSYRHRPLPETGSIGGSPLEEGTGWDRGSSGWGDSENPPVSSVTGLHVEDDDGFIEDNYIQPSEQLPEEEERESHISI", "length": 219, "header": "tr|A0A8V0ZPA8-1|A0A8V0ZPA8_CHICK Isoform 1 of Type III endosome membrane protein TEMP OS=Gallus gallus OX=9031 GN=C1orf210 PE=4 SV=1 CANONICAL=A0A8V0ZPA8-1" }, "locus": { "chromosome": "8", "start_pos": 19344112, "end_pos": 19343456, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055089.1", "url": "https://www.ensembl.org/id/ENSGALT00010055089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033313.1", "url": "https://www.ensembl.org/id/ENSGALP00010033313.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPC6-1", "uniprot_ac": "A0A8V0ZPC6", "uniprot_id": "A0A8V0ZPC6_CHICK", "mass": { "chemical_mass": 11549.0, "monoisotopic_mass": 11549.0 }, "refseq": {}, "gene_names": [ { "name": "SMAGP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC6" } ] } ], "protein_names": [ { "name": "Small cell adhesion glycoprotein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SMAGP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC6", "locus": { "chromosome": "34", "start_pos": 2277652, "end_pos": 2272878, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023840", "url": "https://www.ensembl.org/id/ENSGALG00010023840" } ] } } ], "crossref": [ { "id": "A0A8V0ZPC6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR043243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPC6", "url": "https://www.orthodb.org/?gene=A0A8V0ZPC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47394:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47394:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28228", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28228", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZPC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGALPTLPPEVSSNPTGPILPFQELTTPGLKKAHPPVPHEAANTAVIAVVITLVFLTLLTVLVVIIVYLYRNKGSYLTYEQPAAEADAAVQMEDDPCKEKEEYFI", "length": 106, "header": "tr|A0A8V0ZPC6-1|A0A8V0ZPC6_CHICK Isoform 1 of Small cell adhesion glycoprotein OS=Gallus gallus OX=9031 GN=SMAGP PE=3 SV=1 CANONICAL=A0A8V0ZPC6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC6/entry#A0A8V0ZPC6-1", "sequence": { "sequence": "MEGALPTLPPEVSSNPTGPILPFQELTTPGLKKAHPPVPHEAANTAVIAVVITLVFLTLLTVLVVIIVYLYRNKGSYLTYEQPAAEADAAVQMEDDPCKEKEEYFI", "length": 106, "header": "tr|A0A8V0ZPC6-1|A0A8V0ZPC6_CHICK Isoform 1 of Small cell adhesion glycoprotein OS=Gallus gallus OX=9031 GN=SMAGP PE=3 SV=1 CANONICAL=A0A8V0ZPC6-1" }, "locus": { "chromosome": "34", "start_pos": 2276733, "end_pos": 2276010, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058097.1", "url": "https://www.ensembl.org/id/ENSGALT00010058097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035272.1", "url": "https://www.ensembl.org/id/ENSGALP00010035272.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC6" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC6" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPC8-1", "uniprot_ac": "A0A8V0ZPC8", "uniprot_id": "A0A8V0ZPC8_CHICK", "mass": { "chemical_mass": 155831.0, "monoisotopic_mass": 155831.0 }, "refseq": { "ac": "XP_414033", "name": "capping protein, Arp2/3 and myosin-I linker protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414033" }, "gene_names": [ { "name": "RLTPR", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ] }, { "name": "RLTPR", "type": "synonym", "evidence": [ { "id": "XP_414033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414033" } ] } ], "protein_names": [ { "name": "Capping protein regulator and myosin 1 linker 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8/entry#names_and_taxonomy" } ] }, { "name": "capping protein, Arp2/3 and myosin-I linker protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_414033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414033" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052542.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_414033.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414033", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414033" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RLTPR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8", "locus": {} } ], "crossref": [ { "id": "415666", "url": "https://www.ncbi.nlm.nih.gov/gene/415666", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NVLMFLN", "url": "https://omabrowser.org/oma/group/NVLMFLN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPC8", "url": "https://www.orthodb.org/?gene=A0A8V0ZPC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR63", "url": "https://www.orthodb.org/?gene=A0A8V0ZR63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24112:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24112:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16000", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16000", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17888", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17888", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414033", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414033", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR63", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSPGGIPAELQEGIAASLGAKQILLLKNVQLQVKSKYDDFILVLTPWRAYVLLAALPVRVHSSFSFLEVKDITVLEPSVVVIETDTSSYAFRLMSFDDLEQVVVHVTMSLKKVFPDSSPGTLLKNSPPNLYERIRMVTDSMEEMLQSNQGPCGGFSETYAALCDYNGFTFREEIQWDVDNIYHGQDCREFNLLDFSHLESRDVALSVAALSFNLWFTKLSCKDFRLNQEIAEQLLYMLSKSVKLEELVLENSGLRGDFAQRMAQALSRHPESILHTINLAGNQLEDRGIIAFSRLFEERPKGLQSLNLARTMLTAKGMSALCQALAANEAISSSLRHLDLSGNPGSLAVEDTSSLQSLLGRCSSLTHLSLAATDCSLDTLFGALVHGCCASLVHVDLSKNVYSHRRVKTISPSVKQFFSQARALRHISMAGTKLPPDAVRAVLQGLAYNSHISDLHLDLSSCELRSAGAQVIQDLIPDASAISDLDLSDNGFDSDMVTLVLSIGRSKSIRHVSLGKNFNIKSKDGLVDVLHRIVQLTQEDDCPLQSLSVAESRLKLGTNVLLSALGSNTSLTTLDISGNAMGDTGAKMLAKALQINTKLRTVVWDRNNTTALGLLEVAQALERNYTLKSMPLPMSDVAQAYRSNPERTEEAVHKLQSCLARNQTRRALPTQTFRLQQGILTSSSEQMVNEICLSVQKHIDILSSCPGREMEADILRAEEAIRNANLAVSILPMLYEAGNAPHQSGKLQHKLECLVEEASQTCGREIQAIMQAVLDAAHNLCPPMVQKSGARDQLVNAMSERIHLQEHLSLSAVLDQMVTDVFSKLNEIKLSITAAVADCIVDAVLGDLMAAQCKLAESLPTHGPDLLEPAEDDAAAPARGRNPSELTERGFATEEYKMALRRKNKHFRSIRPTLTVRSLSELELPAAGKARPAPAKDAEPSAGAHPGTPPAQALMDLPTAGERLEHCTKARPRPNRRHKQPPSKPTVQPVAHENSEDRSITRVDEGLEDFFTKRLIAEELPSPTVLESGPGSAPLASSSSRTLKKKIGNFFAFKKPKSSRSSRCEKEPEGGAAAPRSRRSMLSDILRAPSKAGEPGKALSKSEEGALSAEPEHSQTPEAARRIRPKYSREGKSQSLILLPGEDEEALGVRQDKKRHLEKSDGELPNSFEQRVHVMLHRMGVTKGLVTESKKQQSKDSEIKKAGSDGDIVDSSADSPPSLKARTHSVSTDASLRGPSEPSPAWKALGRQLNAELTGLGREQLRRCSAGPEQSGQPACREAWSSSLPRQGRSHTGEPTAGTALPPSPCSAAEDNRLTPRLAVLGARRAVSVHEEQLREPECLAELGTATIPLRLRRSPVLKRRPEASSEPRPAAEAGGTAAQDRLQAALDEAQTAAGVLHGERPPAAAQTVVYAQDSAVDQRSPVPGLGEPALGQ", "length": 1435, "header": "tr|A0A8V0ZPC8-1|A0A8V0ZPC8_CHICK Isoform 1 of Capping protein regulator and myosin 1 linker 2 OS=Gallus gallus OX=9031 GN=RLTPR PE=3 SV=1 CANONICAL=A0A8V0ZPC8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8/entry#A0A8V0ZPC8-1", "sequence": { "sequence": "MAVSPGGIPAELQEGIAASLGAKQILLLKNVQLQVKSKYDDFILVLTPWRAYVLLAALPVRVHSSFSFLEVKDITVLEPSVVVIETDTSSYAFRLMSFDDLEQVVVHVTMSLKKVFPDSSPGTLLKNSPPNLYERIRMVTDSMEEMLQSNQGPCGGFSETYAALCDYNGFTFREEIQWDVDNIYHGQDCREFNLLDFSHLESRDVALSVAALSFNLWFTKLSCKDFRLNQEIAEQLLYMLSKSVKLEELVLENSGLRGDFAQRMAQALSRHPESILHTINLAGNQLEDRGIIAFSRLFEERPKGLQSLNLARTMLTAKGMSALCQALAANEAISSSLRHLDLSGNPGSLAVEDTSSLQSLLGRCSSLTHLSLAATDCSLDTLFGALVHGCCASLVHVDLSKNVYSHRRVKTISPSVKQFFSQARALRHISMAGTKLPPDAVRAVLQGLAYNSHISDLHLDLSSCELRSAGAQVIQDLIPDASAISDLDLSDNGFDSDMVTLVLSIGRSKSIRHVSLGKNFNIKSKDGLVDVLHRIVQLTQEDDCPLQSLSVAESRLKLGTNVLLSALGSNTSLTTLDISGNAMGDTGAKMLAKALQINTKLRTVVWDRNNTTALGLLEVAQALERNYTLKSMPLPMSDVAQAYRSNPERTEEAVHKLQSCLARNQTRRALPTQTFRLQQGILTSSSEQMVNEICLSVQKHIDILSSCPGREMEADILRAEEAIRNANLAVSILPMLYEAGNAPHQSGKLQHKLECLVEEASQTCGREIQAIMQAVLDAAHNLCPPMVQKSGARDQLVNAMSERIHLQEHLSLSAVLDQMVTDVFSKLNEIKLSITAAVADCIVDAVLGDLMAAQCKLAESLPTHGPDLLEPAEDDAAAPARGRNPSELTERGFATEEYKMALRRKNKHFRSIRPTLTVRSLSELELPAAGKARPAPAKDAEPSAGAHPGTPPAQALMDLPTAGERLEHCTKARPRPNRRHKQPPSKPTVQPVAHENSEDRSITRVDEGLEDFFTKRLIAEELPSPTVLESGPGSAPLASSSSRTLKKKIGNFFAFKKPKSSRSSRCEKEPEGGAAAPRSRRSMLSDILRAPSKAGEPGKALSKSEEGALSAEPEHSQTPEAARRIRPKYSREGKSQSLILLPGEDEEALGVRQDKKRHLEKSDGELPNSFEQRVHVMLHRMGVTKGLVTESKKQQSKDSEIKKAGSDGDIVDSSADSPPSLKARTHSVSTDASLRGPSEPSPAWKALGRQLNAELTGLGREQLRRCSAGPEQSGQPACREAWSSSLPRQGRSHTGEPTAGTALPPSPCSAAEDNRLTPRLAVLGARRAVSVHEEQLREPECLAELGTATIPLRLRRSPVLKRRPEASSEPRPAAEAGGTAAQDRLQAALDEAQTAAGVLHGERPPAAAQTVVYAQDSAVDQRSPVPGLGEPALGQ", "length": 1435, "header": "tr|A0A8V0ZPC8-1|A0A8V0ZPC8_CHICK Isoform 1 of Capping protein regulator and myosin 1 linker 2 OS=Gallus gallus OX=9031 GN=RLTPR PE=3 SV=1 CANONICAL=A0A8V0ZPC8-1" }, "locus": { "chromosome": "11", "start_pos": 1178039, "end_pos": 1161273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055118.1", "url": "https://www.ensembl.org/id/ENSGALT00010055118.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033334.1", "url": "https://www.ensembl.org/id/ENSGALP00010033334.1" } ] } }, { "isoform_ac": "A0A8V0ZR63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8/entry#A0A8V0ZR63-1", "sequence": { "sequence": "MAVSPGGIPAELQEGIAASLGAKQILLLKNVQLQVKSKYDDFILVLTPWRAYVLLAALPVRVHSSFSFLEVKDITVLEPSVVVIETDTSSYAFRLMSFDDLEQVVVHVTMSLKKVFPDSSPGTLLKNSPPNLYERIRMVTDSMEEMLQSNQGPCGGFSETYAALCDYNGFTFREEIQWDVDNIYHGQDCREFNLLDFSHLESRDVALSVAALSFNLWFTKLSCKDFRLNQEIAEQLLYMLSKSVKLEELVLENSGLRGDFAQRMAQALSRHPESILHTINLAGNQLEDRGIIAFSRLFEERPKGLQSLNLARTMLTAKGMSALCQALAANEAISSSLRHLDLSGNPGSLAVEDTSSLQSLLGRCSSLTHLSLAATDCSLDTLFGALVHGCCASLVHVDLSKNVYSHRRVKTISPSVKQFFSQARALRHISMAGTKLPPDAVRAVLQGLAYNSHISDLHLDLSSCELRSAGAQVIQDLIPDASAISDLDLSDNGFDSDMVTLVLSIGRSKSIRHVSLGKNFNIKSKDGLVDVLHRIVQLTQEDDCPLQSLSVAESRLKLGTNVLLSALGSNTSLTTLDISGNAMGDTGAKMLAKALQINTKLRTVVWDRNNTTALGLLEVAQALERNYTLKSMPLPMSDVAQAYRSNPERTEEAVHKLQSCLARNQTRRALPTQTFRLQQGILTSSSEQMVNEICLSVQKHIDILSSCPGREMEADILRAEEAIRNANLAVSILPMLYEAGNAPHQSGKLQHKLECLVEEASQTCGREIQAIMQAVLDAAHNLCPPMVQKSGARDQLVNAMSERIHLQEHLSLSAVLDQMVTDVFSKLNEIKLSITAAVADCIVDAVLGDLMAAQCKLAESLPTHGPDLLEPAEDDAAAPARGRNPSELTERGFATEEYKMALRRKNKHFRSIRPTLTVRSLSELELPAAGKARPAPAKDAEPSAGAHPGTPPAQALMDLPTAGERLEHCTKARPRPNRRHKQPPSKPTVQPVAHENSEDRSITRVDEGLEDFFTKRLIAEELPSPTVLESGPGSAPLASSSSRTLKKKIGNFFAFKKPKSSRSSRCEKEPEGGAAAPRSRRSMLSDILRAPSKAGEPGKALSKSEEGALSAEPEHSQTPEAARRIRPKYSREGKSQSLILLPGEDEEALGVRQDKKRHLEKSDGELPNSFEQRVHVMLHRMGVTKGLVTESKKQQSKDSEIKKAGSDGDIVDSSADSPPSLKARTHSVSTDASLRGPSEPSPAWKALGRQLNAELTGLGREQLRRCSAGPEQSGQPACREAWSSSLPRQGRSHTGEPTAGTALPPSPCSAAEGTRSTTGPRWPPWCSPQPLLCPLTPSPVADNRLTPRLAVLGARRAVSVHEEQLREPECLAELGTATIPLRLRRSPVLKRRPEASSEPRPAAEAGGEEQGRH", "length": 1413, "header": "tr|A0A8V0ZR63-1|A0A8V0ZR63_CHICK Computationally mapped isoform of Capping protein regulator and myosin 1 linker 2 OS=Gallus gallus OX=9031 GN=RLTPR PE=3 SV=1 CANONICAL=A0A8V0ZPC8-1" }, "locus": { "chromosome": "11", "start_pos": 1177810, "end_pos": 1161273, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055108.1", "url": "https://www.ensembl.org/id/ENSGALT00010055108.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033326.1", "url": "https://www.ensembl.org/id/ENSGALP00010033326.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZC15-1", "protein_name": "Capping protein regulator and myosin 1 linker 2", "gene_name": "Carmil2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHTPDGISCELRGEITKFLWPKEAELLLKTWLPQEGAEQSHILALLRWRAYLLHTCLPLRVDCTFSYLEVQAMALQETPPRVTFELESLPKLVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRKPTPSSLLARLEKSHPLESTVPSSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQGCRHFCLGDFSHLGSRDLALSVAALSYNLWFRRLSCMDMKLSLEVSEQILHMTSQSSYLEELVLETCGLRGDFVRRLAQALAGHFNSGLRELSLSGNLLDDRGMATLSRHLEHCPGALRKLCLAQTGLTPRGMRALGRALATNATFDSTLTHLDLSGNPGALGASQDGGGLYTFLSRPNVLAYLNLAGTDTALGMLFMALSGGCCANLTHLEASRNIFSRTKSQAVPDALQRFLGGARMLRHLGLAGCKLPPEALRALLDGLALNTQIHDLHLDLSACELRSVGAQVIQDLVCDAGALSSLDLSDNGFGSDMVTLVLAIGRSRSLKHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAESRLKQGASVLIRALGTNPKLSVLDISGNAIGDTGAKMLAKALRVNTRLRSVIWDRNNTSALGLLDVAEALEQNHSLKSMPLPLNDITQAHRSRPELTARAVHQIQACLWRNNRADSTSDRKPCLQPLGLISDHSEQVNELCQSVQEHVELLGCGAGPQGEVAVHQAEDAIQNANFSLSILPILFEAGSSPSHHWQLQQKLEGLLGQVGEICRQDIQDFTQTTLDTTRSLCPQMLQRPGWRKQLEGVLVGSGGLPELLPEHLLQDALTRLRDMRLSITGTLAENIVAQALAGLHAARDRLVESLAQQAPVTVVPAVPPLCGDELTLLESGGVEEFFFPTEEEEEREKDDGSSWKWLEPSNCFLVPSLHGAAEEAERDPELAAPGEDAEPQAGPSARGSPSPAAPGPPAGPLPRMDLPPAGQPLRHPTRARPRPRRQHHHRPPPGGPQVSPALLQEGNGLTARVDEGVEEFFSKRLIQQDRLWAPEEDTATEGGTTPVPRTLRKKLGTLFAFKKPRSTRGPRPDLETSPGAAARARKTTLGDLLRPPARPGRGEEPGGAEGGTSSPDAARRNRPRYTRESKAYSMILLPAEEEAAVGARPDKRRPLERGDTELAPSFEQRVQVVLQRIGVSRGSGGAESKRKQSKDGEIKKAGSDGDIMDSSTETPPISIKSRTHSVSADPSCRPGPGGQGPESATWKTLGQQLNAELRGRGWGQQDGPGPPSPCPSPSPRRTSPAPDILSLPEDPCLGPRNEERPLRLQRSPVLKRRPKLEAPPPPNLGSGLGTKPLPPYPTEPSSPEQSPPSPATDQRGGGPNP", "length": 1368 }, "evidence": [ { "id": "A0A8V0ZPC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPC8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6F5E8-1", "protein_name": "Capping protein, Arp2/3 and myosin-I linker protein 2", "gene_name": "CARMIL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQTPDGISCELRGEITRFLWPKEVELLLKTWLPGEGAVQNHVLALLRWRAYLLHTTCLPLRVDCTFSYLEVQAMALQETPPQVTFELESLRELVLEFPGVAALEQLAQHVAAAIKKVFPRSTLGKLFRRPTPASMLARLERSSPSESTDPCSPCGGFLETYEALCDYNGFPFREEIQWDVDTIYHRQGCRHFSLGDFSHLGSRDLALSVAALSYNLWFRCLSCVDMKLSLEVSEQILHMMSQSSHLEELVLETCSLRGDFVRRLAQALAGHSSSGLRELSLAGNLLDDRGMTALSRHLERCPGALRRLSLAQTGLTPRGMRALGRALATNAAFDSTLTHLDLSGNPGALGASEDSGGLYSFLSRPNVLSFLNLAGTDTALDTVRGCSVGGWMTGRADWRAGRGGLGPPAGVANSLPPQLFAAVSRGCCTSLTHLDASRNVFSRTKSRAAPAALQLFLSRARTLRHLGLAGCKLPPDALRALLDGLALNTHLRDLHLDLSACELRSAGAQVIQDLVCDAGAVSSLDLADNGFGSDMVTLVLAIGRSRSLRHVALGRNFNVRCKETLDDVLHRIVQLMQDDDCPLQSLSVAESRLKLGASVLLRALATNPNLTALDISGNAMGDAGAKLLAKALRVNSRLRSVVWDRNHTSALGLLDVAQALEQNHSLKAMPLPLNDVAQAQRSRPELTARAVHQIQACLLRNNRADPASSDHTTRLQPLGLVSDPSEQEVNELCQSVQEHVELLGCGAGPQGEAAVRQAEDAIQNANFSLSILPILYEAGSSPSHHWQLGQKLEGLLRQVGEVCRQDIQDFTQATLDTARSLCPQMLQGSSWREQLEGVLAGSRGLPELLPEQLLQDAFTRLRDMRLSITGTLAESIVAQALAGLSAARDQLVESLAQQATVTMPPALPAPDGGEPSLLEPGELEGLFFPEEKEEEKEKDDSPPQKWPELSHGLHLVPFIHSAAEEAEPEPELAAPGEDAEPQAGPSARGSPSPAAPGPPAGPLPRMDLPLAGQPLRHPTRARPRPRRQHHHRPPPGGPQVPPALPQEGNGLSARVDEGVEEFFSKRLIQQDRLWAPEEDPATEGGATPVPRTLRKKLGTLFAFKKPRSTRGPRTDLETSPGAAPRTRKTTFGDLLRPPTRPSRGEELGGAEGDTSSPDPAGRSRPRYTRDSKAYSMILLPAEEEATLGARPDKRRPLERGETELAPSFEQRVQVMLQRIGVSRGSGGAEGKRKQSKDGEIKKAGSDGDIMDSSTEAPPISIKSRTHSVSADPSCRPGPGSQGPESATWKTLGQQLNAELRSRGWGQQDGPGPPSPGQSPSPCRTSPSPDSLGLPEDPCLGPRNEDGQLRPRPLSAGRRAVSVHEDQLQAPAERPLRLQRSPVLKRRPKLEAPPSPSLGSGLGTEPLPPQPTEPSSPERSPPSPATDQRGGGPNP", "length": 1435 }, "evidence": [ { "id": "A0A8V0ZPC8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "ruffle", "id": "GO:0001726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "macropinosome", "id": "GO:0044354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044354", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "intermediate filament cytoskeleton", "id": "GO:0045111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045111", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 10, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "regulation of Arp2/3 complex-mediated actin nucleation", "id": "GO:0034315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034315", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "actin filament network formation", "id": "GO:0051639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051639", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "positive regulation of lamellipodium assembly", "id": "GO:0010592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010592", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "wound healing, spreading of cells", "id": "GO:0044319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044319", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "establishment or maintenance of monopolar cell polarity", "id": "GO:0061339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061339", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "positive regulation of extracellular matrix disassembly", "id": "GO:0090091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "positive regulation of ruffle assembly", "id": "GO:1900029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900029", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" }, { "name": "negative regulation of barbed-end actin filament capping", "id": "GO:2000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPC8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" }, { "id": "PF16000", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16000" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CARMIL C-terminal", "eco_id": "ECO_0000259", "start_pos": 779, "end_pos": 1063, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZPC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPC8" }, { "id": "PF17888", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CARMIL pleckstrin homology", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 117, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA 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This record is derived from a genomic sequence (NC_052580.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040533687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040533687" } ] }, { "annotation": "Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPE6#function" }, { "database": "UniProtKB", "id": "ARBA00049587", "url": "https://www.uniprot.org/uniprotkb/ARBA00049587#function" }, { "database": "UniProtKB", "id": "A0A8V0ZPF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF1#function" }, { "database": "UniProtKB", "id": "A0A8V0ZWP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWP5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC39", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF1", "locus": { "chromosome": "8", "start_pos": 11666571, "end_pos": 11654494, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023852", "url": "https://www.ensembl.org/id/ENSGALG00010023852" } ] } } ], "crossref": [ { "id": "A0A8V0ZPF1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "424469", "url": "https://www.ncbi.nlm.nih.gov/gene/424469", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DMPALEW", "url": "https://omabrowser.org/oma/group/DMPALEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPE6", "url": "https://www.orthodb.org/?gene=A0A8V0ZPE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPF1", "url": "https://www.orthodb.org/?gene=A0A8V0ZPF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWP5", "url": "https://www.orthodb.org/?gene=A0A8V0ZWP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040533687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040533687", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPE6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNHGKSLKTKYLSCSPVIEPEHVRIMTETAVCIGSFTAVKTLWEVRIQKINEELRKEKEFRERSAGRLLLVWEERATLAKLKEKVINEDGRAVLKIEEEEWKTLPSCLLKLVHLQEWQLHRTSLQKIPQFVGRFHNLVVLDLSRNSIESIPKEIGQLTGLQELLLSYNRIKFVPKEISNCISLERLELAVNRNIRDLPPQLSDLKKLSHIDLCMNQFTTIPSALLSMPNLEWLDMGGNQLQKLPDAIDRMENLHTLWLQRNEINSLPETIVNMKNLSTLVLSNNKLKDIPSCMMHMTNLRFVNFRDNPLELEITLPPCEKTEEEEQQEMFGIEFMHMYIQESLKKTGNVESCTSDTSPIITANAEGT", "length": 367, "header": "tr|A0A8V0ZPF1-1|A0A8V0ZPF1_CHICK Isoform 1 of Leucine-rich repeat-containing protein 39 OS=Gallus gallus OX=9031 GN=LRRC39 PE=4 SV=1 CANONICAL=A0A8V0ZPF1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF1/entry#A0A8V0ZPE6-1", "sequence": { "sequence": "MTETAVCIGSFTAVKTLWEVRIQKINEELRKEKEFRERSAGRLLLVWEERATLAKLKEKVINEDGRAVLKIEEEEWKTLPSCLLKLVHLQEWQLHRTSLQKIPQFVGRFHNLVVLDLSRNSIESIPKEIGQLTGLQELLLSYNRIKFVPKEISNCISLERLELAVNRNIRDLPPQLSDLKKLSHIDLCMNQFTTIPSALLSMPNLEWLDMGGNQLQKLPDAIDRMENLHTLWLQRNEINSLPETIVNMKNLSTLVLSNNKLKDIPSCMMHMTNLRFVNFRDNPLELEITLPPCEKTEEEEQQEMFGIEFMHMYIQESLKKTGIFFVNSSPSGMK", "length": 334, "header": "tr|A0A8V0ZPE6-1|A0A8V0ZPF1_CHICK Computationally mapped isoform of Leucine-rich repeat-containing protein 39 OS=Gallus gallus OX=9031 GN=LRRC39 PE=4 SV=1 CANONICAL=A0A8V0ZPF1-1" }, "locus": { "chromosome": "8", "start_pos": 11663252, "end_pos": 11656751, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058125.1", "url": "https://www.ensembl.org/id/ENSGALT00010058125.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035292.1", "url": "https://www.ensembl.org/id/ENSGALP00010035292.1" } ] } }, { "isoform_ac": "A0A8V0ZPF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF1/entry#A0A8V0ZPF1-1", "sequence": { "sequence": "MNHGKSLKTKYLSCSPVIEPEHVRIMTETAVCIGSFTAVKTLWEVRIQKINEELRKEKEFRERSAGRLLLVWEERATLAKLKEKVINEDGRAVLKIEEEEWKTLPSCLLKLVHLQEWQLHRTSLQKIPQFVGRFHNLVVLDLSRNSIESIPKEIGQLTGLQELLLSYNRIKFVPKEISNCISLERLELAVNRNIRDLPPQLSDLKKLSHIDLCMNQFTTIPSALLSMPNLEWLDMGGNQLQKLPDAIDRMENLHTLWLQRNEINSLPETIVNMKNLSTLVLSNNKLKDIPSCMMHMTNLRFVNFRDNPLELEITLPPCEKTEEEEQQEMFGIEFMHMYIQESLKKTGNVESCTSDTSPIITANAEGT", "length": 367, "header": "tr|A0A8V0ZPF1-1|A0A8V0ZPF1_CHICK Isoform 1 of Leucine-rich repeat-containing protein 39 OS=Gallus gallus OX=9031 GN=LRRC39 PE=4 SV=1 CANONICAL=A0A8V0ZPF1-1" }, "locus": { "chromosome": "8", "start_pos": 11664234, "end_pos": 11654575, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058133.1", "url": "https://www.ensembl.org/id/ENSGALT00010058133.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035297.1", "url": "https://www.ensembl.org/id/ENSGALP00010035297.1" } ] } }, { "isoform_ac": "A0A8V0ZWP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF1/entry#A0A8V0ZWP5-1", "sequence": { "sequence": "LASRNNIVTHSKLLLVWEERATLAKLKEKVINEDGRAVLKIEEEEWKTLPSCLLKLVHLQEWQLHRTSLQKIPQFVGRFHNLVVLDLSRNSIESIPKEIGQLTGLQELLLSYNRIKFVPKEISNCISLERLELAVNRNIRDLPPQLSDLKKLSHIDLCMNQFTTIPSALLSMPNLEWLDMGGNQLQKLPDAIDRMENLHTLWLQRNEINSLPETIVNMKNLSTLVLSNNKLKDIPSCMMHMTNLRFVNFRDNPLELEITLPPCEKTEEEEQQEMFGIEFMHMYIQESLKKTGNVESCTSDTSPIITANAEGT", "length": 312, "header": "tr|A0A8V0ZWP5-1|A0A8V0ZPF1_CHICK Computationally mapped isoform of Leucine-rich repeat-containing protein 39 OS=Gallus gallus OX=9031 GN=LRRC39 PE=4 SV=1 CANONICAL=A0A8V0ZPF1-1" }, "locus": { "chromosome": "8", "start_pos": 11664234, "end_pos": 11657645, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058131.1", "url": "https://www.ensembl.org/id/ENSGALT00010058131.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035296.1", "url": "https://www.ensembl.org/id/ENSGALP00010035296.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZXS4-1", "protein_name": "Leucine-rich repeat-containing protein 39", "gene_name": "Lrrc39", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTESVVCTGAVSTVKEVWEERIKKHHEDVKREKEFQQKLVRIWEDRVSLTKLKEKVTREDGRIILRIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQHLIVLDLSRNTISEIPRGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDISDLPTELSKLLKLTHLDLSMNQFTTIPLAVLDMPALEWLDMGSNSLQQLPDTLDRMQSLHTLWLQRNEITCLPETIRNMKNLGTLVLSNNKLQDIPGCMEEMTSLRFVNFRDNPLRLEVTLPPSDDVDGEEEQELFGLQFMHAYIQESRRTEDQVNCLTHTPSSTRSDG", "length": 334 }, "evidence": [ { "id": "A0A8V0ZPF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZPF1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R6I3-1", "protein_name": "Leucine-rich repeat-containing protein 39", "gene_name": "lrrc39", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGVTVCCGTVNSIKALWETRIKKTKDDLKKEKEQKDRRAVGRLTGAWEDRIILAKLKEKIVTEEGRVILRIEKEEWKTLPPALVQLSQIQEWQLHRIGLQRIPRFISSFQSLIVLDLSRNSVTEIPKEIGKLTRLRELLLSYNRVSYVPEELGCCENLEKLELAMNRDLDELPTQLSNLKKLSHLDLSMNQFTTIPDCVVNLPSLEWLDMGSNILETLPDNIHRMEKLHTLWLPRNELEYLPDNISRMKSLDTLVLSKNKLRDIPPLMEGMSNLRFVNFRDNPLTYDVTLPDLNEDVEEEENDREMFGREFMNFYIQEARKRGSQNFTSVLNVMLEGVSETA", "length": 343 }, "evidence": [ { "id": "A0A8V0ZPF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZPF1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3ZC49-1", "protein_name": "Leucine-rich repeat-containing protein 39", "gene_name": "LRRC39", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSENVVSTGAVNAVKEVWEKRIKKLNEDLKREKEFQQKLVRIWEERVCLTKLREKVTKEDGRVILKIEKEEWKTLPSSLLKLNQLQEWQLHRIGLLKIPEFIGRFQNLIVLDLSRNTITEIPRGIGLLTRLQELILSYNRIKTVPMELSYCASLEKLELAVNRDISDLPQELSNLLKLTHLDLSMNLFTTIPPAVLNMPALEWLDMGSNRLEQLPDTIERMQNLHTLWLQRNEITCLPETISSMKNLSTLVLSNNKLQDIPVCMEKMTNLRFVNFRDNPLKLEVTLPPSENIEEEEERELFGLQFMHTYIQESRRAGNQVNCSTTSPNSIDADG", "length": 334 }, "evidence": [ { "id": "A0A8V0ZPF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZPF1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BGI7-1", "protein_name": "Leucine-rich repeat-containing protein 39", "gene_name": "Lrrc39", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTESAVCTGAVSAVKEVWEERIKKHHEDVKREKEFQHKLVRIWEDRVSLTKLKEKVTREDGRVILRIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQHLIVLDLSRNTISEIPRGIGLLTRLQELILSYNKIKTVPKELSNCTSLEKLELAVNRDISDLPPELSKLLKLTHLDLSMNQFTTIPHAVLDMPALEWLDMGSNSLQQLPDSLDRMRSLHTLWLQRNEITCLPETIKNMKNLGTLVLSNNKLQDIPGCMEEMTNLRFVNFRDNPLRLEVTLPPSDNTDGEEEQELFGLQFMHAYIQESRRTEDQVNCLTQMPSSIHSDGESN", "length": 337 }, "evidence": [ { "id": "A0A8V0ZPF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZPF1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96DD0-1", "protein_name": "Leucine-rich repeat-containing protein 39", "gene_name": "LRRC39", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTENVVCTGAVNAVKEVWEKRIKKLNEDLKREKEFQHKLVRIWEERVSLTKLREKVTREDGRVILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLKLKVSLPPSEGTDEEEERELFGLQFMHTYIQESRRRADHQVNGSTTLPISINTDG", "length": 335 }, "evidence": [ { "id": "A0A8V0ZPF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZPF1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPF1" }, { "id": "PF23598", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disease resistance R13L4/SHOC-2-like LRR", "eco_id": "ECO_0000259", "start_pos": 106, "end_pos": 215, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 275, "end_pos": 277 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPI3-1", "uniprot_ac": "A0A8V0ZPI3", "uniprot_id": "A0A8V0ZPI3_CHICK", "mass": { "chemical_mass": 40432.0, "monoisotopic_mass": 40432.0 }, "refseq": { "ac": "XP_015152293", "name": "DNA fragmentation factor subunit beta isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152293" }, "gene_names": [ { "name": "DFFB", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ] }, { "name": "DFFB", "type": "synonym", "evidence": [ { "id": "XP_015152293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152293" } ] } ], "protein_names": [ { "name": "DNA fragmentation factor subunit beta", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3/entry#names_and_taxonomy" } ] }, { "name": "DNA fragmentation factor subunit beta isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015152293", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152293" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015152293.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152293", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152293" } ] }, { "annotation": "Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3#function" }, { "database": "UniProtKB", "id": "ARBA00053660", "url": "https://www.uniprot.org/uniprotkb/ARBA00053660#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DFFB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3", "locus": { "chromosome": "21", "start_pos": 901114, "end_pos": 912383, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021223", "url": "https://www.ensembl.org/id/ENSGALG00010021223" } ] } } ], "crossref": [ { "id": "A0A8V0ZPI3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPI3", "database": "AlphaFoldDB", "categories": [] }, { "id": "374158", "url": "https://www.ncbi.nlm.nih.gov/gene/374158", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044925", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044925", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPI3", "url": "https://www.orthodb.org/?gene=A0A8V0ZPI3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13067:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13067:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09230", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09230", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-140342", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-140342", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015152293", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152293", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPLRGFRLRRPGSAQKFGAAAGSLRGLLRKGCRLLQLPLAGSRLCLYEDGTELSEAFFRTLPPQTELVLLRPGESWPGCCGDVERFLAALCSRTDAVVEAARRLLEDERAPRRQRLLADLIHNLSGDSAAERRDEDGKWFEGLESRFKNKSSYMRYSCESRIRSYMKEVSNFISNVHPTARDAYKRILDLMSDKLKSVKYNGSYFDRTEEEAAMRLCTKEGWFSCQGPFDRDDCPCKHSINPYTNRESRILFSTWNLDHMYQQVCSAPNGTSSPCQAHRVAGASLQLLGNRRSPAWFTFCTYFAELYPAHPFEPSLGRALPFSTAMPTRLLQPHPKANPQHISCQRVVATCATLSL", "length": 358, "header": "tr|A0A8V0ZPI3-1|A0A8V0ZPI3_CHICK Isoform 1 of DNA fragmentation factor subunit beta OS=Gallus gallus OX=9031 GN=DFFB PE=4 SV=1 CANONICAL=A0A8V0ZPI3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3/entry#A0A8V0ZPI3-1", "sequence": { "sequence": "MAAPLRGFRLRRPGSAQKFGAAAGSLRGLLRKGCRLLQLPLAGSRLCLYEDGTELSEAFFRTLPPQTELVLLRPGESWPGCCGDVERFLAALCSRTDAVVEAARRLLEDERAPRRQRLLADLIHNLSGDSAAERRDEDGKWFEGLESRFKNKSSYMRYSCESRIRSYMKEVSNFISNVHPTARDAYKRILDLMSDKLKSVKYNGSYFDRTEEEAAMRLCTKEGWFSCQGPFDRDDCPCKHSINPYTNRESRILFSTWNLDHMYQQVCSAPNGTSSPCQAHRVAGASLQLLGNRRSPAWFTFCTYFAELYPAHPFEPSLGRALPFSTAMPTRLLQPHPKANPQHISCQRVVATCATLSL", "length": 358, "header": "tr|A0A8V0ZPI3-1|A0A8V0ZPI3_CHICK Isoform 1 of DNA fragmentation factor subunit beta OS=Gallus gallus OX=9031 GN=DFFB PE=4 SV=1 CANONICAL=A0A8V0ZPI3-1" }, "locus": { "chromosome": "21", "start_pos": 912354, "end_pos": 902118, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051441.1", "url": "https://www.ensembl.org/id/ENSGALT00010051441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030632.1", "url": "https://www.ensembl.org/id/ENSGALP00010030632.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-140342", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-140342", "resource": "Reactome", "description": "Apoptosis induced DNA fragmentation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" }, { "name": "DNA endonuclease activity", "id": "GO:0004520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004520", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" }, { "name": "DNA nuclease activity", "id": "GO:0004536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "apoptotic chromosome condensation", "id": "GO:0030263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" }, { "name": "apoptotic DNA fragmentation", "id": "GO:0006309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006309", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" }, { "name": "negative regulation of apoptotic DNA fragmentation", "id": "GO:1902511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902511", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI3" }, { "id": "PS51135", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51135" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CIDE-N", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 80, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 271, "end_pos": 273 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPI6-1", "uniprot_ac": "A0A8V0ZPI6", "uniprot_id": "A0A8V0ZPI6_CHICK", "mass": { "chemical_mass": 68818.0, "monoisotopic_mass": 68818.0 }, "refseq": { "ac": "NP_001001782", "name": "thrombopoietin receptor precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001782" }, "gene_names": [ { "name": "MPL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6" } ] }, { "name": "MPL", "type": "synonym", "evidence": [ { "id": "NP_001001782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001782" } ] }, { "name": "c-mpl", "type": "synonym", "evidence": [ { "id": "NP_001001782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001782" } ] } ], "protein_names": [ { "name": "MPL proto-onco, thrombopoietin receptor", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6/entry#names_and_taxonomy" } ] }, { "name": "myeloproliferative leukemia virus oncogene", "type": "synonym", "evidence": [ { "id": "NP_001001782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001782" } ] }, { "name": "thrombopoietin receptor precursor", "type": "synonym", "evidence": [ { "id": "NP_001001782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001782" } ] }, { "name": "thrombopoietin receptor", "type": "synonym", "evidence": [ { "id": "NP_001001782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001782" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AY613435.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992323, SAMEA103992527 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On Sep 23, 2021 this sequence version replaced NP_001001782.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001001782", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001782" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MPL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6", "locus": { "chromosome": "8", "start_pos": 19365614, "end_pos": 19361455, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022689", "url": "https://www.ensembl.org/id/ENSGALG00010022689" } ] } } ], "crossref": [ { "id": "A0A8V0ZPI6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPI6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "414804", "url": "https://www.ncbi.nlm.nih.gov/gene/414804", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:414804", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:414804", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZPI6", "url": "https://www.orthodb.org/?gene=A0A8V0ZPI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRD4", "url": "https://www.orthodb.org/?gene=A0A8V0ZRD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001001782", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001001782", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGGMAACLHQGWLPALLAAVLLSRHSPATDTEPVTSQDAALLAEVPEDILCFSRSFEDLTCFWDEEEASAIHRFYYWDAPTTCAVSTQRSGVSGMRHICVFPSQDVRLFTPLHVLVLDTTTNRTRHRRELSVDAVGLIAPPVNISARWAGAAGQLRVSWQPPLADYPNFFLYEVCYHPMTPTVTPRGTAPGDLPARPTGRAHPPTARGAAASQGTGQGLVQADTWVVLRELQPGVRYHIQVRSKPDGTSMDGVWGPWSEVVVAETPHSSGDIGLHCSTPDLRCVRCVWSWDPAEHQSTHELFYRASPSGAGMREDTWQQCEDASTGTQGSHACTFQPTAGSPIAVLVNVTRLHEPPVLSYFKEPFWLHQAVLTEAPQHVQATASQGRFSLQWLPPLEALAEQLEYQVRYATDNSLEWKVLQVPRAARKEVLDLRPGARYRAQVRAQPGGPQYQGSWSAWSQPVVVDVAAEAGKGREGAEGARGRAEENQRAVQNRRSVAGWVIPSVTVAPLIFTGVLLGLRCTFPSLYSSVKQRLWPPVPDLHRALGTFLHDSPKQGQPSAFYKQPPEDAVLPCLLEVLPGPRGEPGDPPPEPAASRPAPSTDIANHSYLLMGGWEPRGEPSAPFPPGI", "length": 630, "header": "tr|A0A8V0ZPI6-1|A0A8V0ZPI6_CHICK Isoform 1 of MPL proto-onco, thrombopoietin receptor OS=Gallus gallus OX=9031 GN=MPL PE=4 SV=1 CANONICAL=A0A8V0ZPI6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6/entry#A0A8V0ZPI6-1", "sequence": { "sequence": "MTGGMAACLHQGWLPALLAAVLLSRHSPATDTEPVTSQDAALLAEVPEDILCFSRSFEDLTCFWDEEEASAIHRFYYWDAPTTCAVSTQRSGVSGMRHICVFPSQDVRLFTPLHVLVLDTTTNRTRHRRELSVDAVGLIAPPVNISARWAGAAGQLRVSWQPPLADYPNFFLYEVCYHPMTPTVTPRGTAPGDLPARPTGRAHPPTARGAAASQGTGQGLVQADTWVVLRELQPGVRYHIQVRSKPDGTSMDGVWGPWSEVVVAETPHSSGDIGLHCSTPDLRCVRCVWSWDPAEHQSTHELFYRASPSGAGMREDTWQQCEDASTGTQGSHACTFQPTAGSPIAVLVNVTRLHEPPVLSYFKEPFWLHQAVLTEAPQHVQATASQGRFSLQWLPPLEALAEQLEYQVRYATDNSLEWKVLQVPRAARKEVLDLRPGARYRAQVRAQPGGPQYQGSWSAWSQPVVVDVAAEAGKGREGAEGARGRAEENQRAVQNRRSVAGWVIPSVTVAPLIFTGVLLGLRCTFPSLYSSVKQRLWPPVPDLHRALGTFLHDSPKQGQPSAFYKQPPEDAVLPCLLEVLPGPRGEPGDPPPEPAASRPAPSTDIANHSYLLMGGWEPRGEPSAPFPPGI", "length": 630, "header": "tr|A0A8V0ZPI6-1|A0A8V0ZPI6_CHICK Isoform 1 of MPL proto-onco, thrombopoietin receptor OS=Gallus gallus OX=9031 GN=MPL PE=4 SV=1 CANONICAL=A0A8V0ZPI6-1" }, "locus": { "chromosome": "8", "start_pos": 19365590, "end_pos": 19361489, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055196.1", "url": "https://www.ensembl.org/id/ENSGALT00010055196.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033395.1", "url": "https://www.ensembl.org/id/ENSGALP00010033395.1" } ] } }, { "isoform_ac": "A0A8V0ZRD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6/entry#A0A8V0ZRD4-1", "sequence": { "sequence": "MTGGMAACLHQGWLPALLAAVLLSRHSPATDTEPVTSQDAALLAEVPEDILCFSRSFEDLTCFWDEEEASAIHRFYYWYSRDAPTTCAVSTQRSGVSGMRHICVFPSQDVRLFTPLHVLVLDTTTNRTRHRRELSVDAVGLIAPPVNISARWAGAAGQLRVSWQPPLADYPNFFLYEVCYHPMTPTVTPRGTAPGDLPARPTGRAHPPTARGAAASQGTGQGLVQADTWVVLRELQPGVRYHIQVRSKPDGTSMDGVWGPWSEVVVAETPHSSGDIGLHCSTPDLRCVRCVWSWDPAEHQSTHELFYRASPSGAGMREDTWQQCEDASTGTQGSHACTFQPTAGSPIAVLVNVTRLHEPPVLSYFKEPFWLHQAVLTEAPQHVQATASQGRFSLQWLPPLEALAEQLEYQVRYATDNSLEWKVLQVPRAARKEVLDLRPGARYRAQVRAQPGGPQYQGSWSAWSQPVVVDVAAEAGWVIPSVTVAPLIFTGVLLGLRCTFPSLYSSVKQRLWPPVPDLHRALGTFLHDSPKQGQPSAFYKQPPEDAVLPCLLEVLPGPRGEPGDPPPEPAASRPAPSTDIANHSYLLMGGWEPRGEPSAPFPPGI", "length": 605, "header": "tr|A0A8V0ZRD4-1|A0A8V0ZRD4_CHICK Computationally mapped isoform of MPL proto-onco, thrombopoietin receptor OS=Gallus gallus OX=9031 GN=MPL PE=4 SV=1 CANONICAL=A0A8V0ZPI6-1" }, "locus": { "chromosome": "8", "start_pos": 19365590, "end_pos": 19361489, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055192.1", "url": "https://www.ensembl.org/id/ENSGALT00010055192.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033392.1", "url": "https://www.ensembl.org/id/ENSGALP00010033392.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 185, "start_aa": "Thr", "end_pos": 185, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr185", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:414804", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:414804", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "thrombopoietin receptor activity", "id": "GO:0038164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038164", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6" } ], "pmid": "" }, { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "platelet formation", "id": "GO:0030220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030220", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6" } ], "pmid": "" }, { "name": "thrombopoietin-mediated signaling pathway", "id": "GO:0038163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038163", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6" } ], "pmid": "" }, { "name": "regulation of hemopoiesis", "id": "GO:1903706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903706", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": 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"sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPI7-1", "uniprot_ac": "A0A8V0ZPI7", "uniprot_id": "A0A8V0ZPI7_CHICK", "mass": { "chemical_mass": 25312.0, "monoisotopic_mass": 25312.0 }, "refseq": {}, "gene_names": [ { "name": "CHCHD4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI7" } ] } ], "protein_names": [ { "name": "Coiled-coil-helix-coiled-coil-helix domain 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"AlphaFoldDB", "categories": [] }, { "id": "IPR010625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPI7", "url": "https://www.orthodb.org/?gene=A0A8V0ZPI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21622", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21622", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21622:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21622:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06747", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06747", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZPI7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "HRSALCPDWLLLSRLGEAVQQRAPEVRACASGDQGSLRVLPEVRGHGVELRGTAAVLEEEEREQERGGREGRGTVAEPVCGRIEREGSGRLRAAPPCPTAGKDKIIFVTKEDHETPSSAELVADDPDDPYEEQGLILPNGDINWNCPCLGGMASGPCGEQFKSAFSCFHYSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDENEEKEKSSKDLEATPVEDSVAKEEKGSS", "length": 231, "header": "tr|A0A8V0ZPI7-1|A0A8V0ZPI7_CHICK Isoform 1 of Coiled-coil-helix-coiled-coil-helix domain containing 4 OS=Gallus gallus OX=9031 GN=CHCHD4 PE=1 SV=1 CANONICAL=A0A8V0ZPI7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPI7/entry#A0A8V0ZPI7-1", "sequence": { "sequence": 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"id": "A0A8V0ZPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK2" } ], "pmid": "" }, { "name": "phospholipid catabolic process", "id": "GO:0009395", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009395", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK2" } ], "pmid": "" }, { "name": "positive regulation of angiogenesis", "id": "GO:0045766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK2" } ], "pmid": "" }, { "name": "cell-matrix adhesion", "id": "GO:0007160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007160", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK2" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK2" } ], "pmid": "" }, { "name": "phospholipid homeostasis", "id": "GO:0055091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055091", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK2" } ], "pmid": "" }, { "name": "negative regulation of very-low-density lipoprotein particle remodeling", "id": "GO:0010903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010903", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK2" } ], "pmid": "" }, { "name": "positive regulation of lipid catabolic process", "id": "GO:0050996", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050996", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK2" } ], "pmid": "" }, { "name": "triglyceride homeostasis", "id": "GO:0070328", "url": 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"sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPK7-1", "uniprot_ac": "A0A8V0ZPK7", "uniprot_id": "A0A8V0ZPK7_CHICK", "mass": { "chemical_mass": 40000.0, "monoisotopic_mass": 40000.0 }, "refseq": {}, "gene_names": [ { "name": "SAMD8", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7" } ] } ], "protein_names": [ { "name": "Sphingomyelin synthase-related protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7/entry#names_and_taxonomy" } ] }, { "name": "3.1.4.62", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7/entry#names_and_taxonomy" } ] }, { "name": "Ceramide phosphoethanolamine synthase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7/entry#names_and_taxonomy" } ] }, { "name": "Phosphatidylethanolamine Phospholipase C", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7/entry#names_and_taxonomy" } ] }, { "name": "Sterile alpha motif domain-containing protein 8", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Has phospholipase C (PLC) activity. Shows specificity for phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE), hydrolyzing PE to produce phosphoethanolamine and diacylglycerol (1,2-diacyl-sn-glycerol, DAG). This reaction might act as a regulatory switch to activate serine palmitoyltransferase (SPT) and promote sphingolipid metabolism. Can also function as a ceramide phosphoethanolamine (N-acylsphingoid 1-phosphoethanolamine, CPE) synthase when intracellular ceramide levels are elevated. Binds the headgroup from PE, which is smaller and more hydrophilic than the phosphocholine headgroup transferred in the canonical sphingomyelin synthesis (SMS) reaction by SMS1 or SMS2, and transfers it on to the primary hydroxyl of a ceramide in the lumen of the endoplasmic reticulum. Plays a role as a ceramide sensor, helping to regulate ceramide homeostasis in the endoplasmic reticulum, which is critical for maintaining the integrity of the early secretory pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7#function" }, { "database": "UniProtKB", "id": "ARBA00094346", "url": "https://www.uniprot.org/uniprotkb/ARBA00094346#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SAMD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7", "locus": { "chromosome": "6", "start_pos": 15651644, "end_pos": 15657680, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023889", "url": "https://www.ensembl.org/id/ENSGALG00010023889" } ] } } ], "crossref": [ { "id": "A0A8V0ZPK7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09515", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09515", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPK7", "url": "https://www.orthodb.org/?gene=A0A8V0ZPK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21290", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21290", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21290:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21290:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "36079", "url": "https://www.rhea-db.org/rhea/36079", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "42128", "url": "https://www.rhea-db.org/rhea/42128", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "42136", "url": "https://www.rhea-db.org/rhea/42136", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "42144", "url": "https://www.rhea-db.org/rhea/42144", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "42148", "url": "https://www.rhea-db.org/rhea/42148", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78951", "url": "https://www.rhea-db.org/rhea/78951", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZPK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGNNQLCIRRWTTKNVAKWLKEEGFCEYVDILCNRHRLDGITLLTLTEYDLRSPPLEIKILGDIKRLMLSIRKLQKQHIDVLEELGYNSDSHIGAVCATVGSLQGADWFCNGEVPRDYDGPITDLNGDQYQYANGKNKHLTRRLDPEYWKTVLSCVYVFIVFGFTSFVMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFAMTEVCGVILCYIWLLVLLLHKHRYSIYTPAKAVQPYGDSILTTLRYNVCYLTLCARPALAVYWKVVWQCLGKTPAGICNMEWLWNDSYWSTYMWRLYVQWPHCCPDHAQLLCHRIYTKELELLAHLILGPQPLWNLLHFGCT", "length": 344, "header": "tr|A0A8V0ZPK7-1|A0A8V0ZPK7_CHICK Isoform 1 of Sphingomyelin synthase-related protein 1 OS=Gallus gallus OX=9031 GN=SAMD8 PE=3 SV=1 CANONICAL=A0A8V0ZPK7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7/entry#A0A8V0ZPK7-1", "sequence": { "sequence": "MAGNNQLCIRRWTTKNVAKWLKEEGFCEYVDILCNRHRLDGITLLTLTEYDLRSPPLEIKILGDIKRLMLSIRKLQKQHIDVLEELGYNSDSHIGAVCATVGSLQGADWFCNGEVPRDYDGPITDLNGDQYQYANGKNKHLTRRLDPEYWKTVLSCVYVFIVFGFTSFVMVIVHERVPDMQTYPPLPDIFLDSVPRIPWAFAMTEVCGVILCYIWLLVLLLHKHRYSIYTPAKAVQPYGDSILTTLRYNVCYLTLCARPALAVYWKVVWQCLGKTPAGICNMEWLWNDSYWSTYMWRLYVQWPHCCPDHAQLLCHRIYTKELELLAHLILGPQPLWNLLHFGCT", "length": 344, "header": "tr|A0A8V0ZPK7-1|A0A8V0ZPK7_CHICK Isoform 1 of Sphingomyelin synthase-related protein 1 OS=Gallus gallus OX=9031 GN=SAMD8 PE=3 SV=1 CANONICAL=A0A8V0ZPK7-1" }, "locus": { "chromosome": "6", "start_pos": 15657650, "end_pos": 15652387, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058203.1", "url": "https://www.ensembl.org/id/ENSGALT00010058203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035358.1", "url": "https://www.ensembl.org/id/ENSGALP00010035358.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of ceramide biosynthetic process", "id": "GO:2000303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000303", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7" } ], "pmid": "" }, { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphotransferase activity, for other substituted phosphate groups", "id": "GO:0016780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016780", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPK7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36079", "name": "", "equation": "an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphing-4-enine 1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q7T3T4-1", "A0A3Q2U7T0-1", "A0A8V0ZPK7-1" ], "evidence": [ { "id": "36079", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36079" } ] }, { "id": "42128", "name": "", "equation": "N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-sphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZPK7-1" ], "evidence": [ { "id": "42128", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42128" } ] }, { "id": "42136", "name": "", "equation": "an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZPK7-1" ], "evidence": [ { "id": "42136", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42136" } ] }, { "id": "42144", "name": "", "equation": "N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZPK7-1" ], "evidence": [ { "id": "42144", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42144" } ] }, { "id": "42148", "name": "", "equation": "an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZPK7-1" ], "evidence": [ { "id": "42148", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/42148" } ] }, { "id": "78951", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = phosphoethanolamine + a 1,2-diacyl-sn-glycerol + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZPK7-1" ], "evidence": [ { "id": "78951", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78951" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A3Q2U7T0", "gene_name": "SGMS1", "activity": [ { "ec_number": "2.7.8.27", "activity": "an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol.", "evidence": [ { "id": "A0A3Q2U7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7T0" } ] }, { "ec_number": "2.7.8.27", "activity": "", "evidence": [ { "id": "A0A3Q2U7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U7T0" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK7", "gene_name": "SAMD8", "activity": [ { "ec_number": "3.1.4.62", "activity": "a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = phosphoethanolamine + a 1,2-diacyl-sn-glycerol + H(+).", "evidence": [ { "id": "A0A8V0ZPK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7" } ] }, { "ec_number": "3.1.4.62", "activity": "", "evidence": [ { "id": "A0A8V0ZPK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK7" } ] } ] }, { "uniprot_ac": "Q7T3T4", "gene_name": "SGMS1", "activity": [ { "ec_number": "2.7.8.27", "activity": "an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol.", "evidence": [ { "id": "Q7T3T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T3T4" } ] }, { "ec_number": "2.7.8.27", "activity": "", "evidence": [ { "id": "Q7T3T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T3T4" } ] } ] } ], "biomarkers": [], "structures": [], 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"https://www.ebi.ac.uk/interpro/entry/IPR038558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041513", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041513", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPL2", "url": "https://www.orthodb.org/?gene=A0A8V0ZPL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUT6", "url": "https://www.orthodb.org/?gene=A0A8V0ZUT6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUU1", "url": "https://www.orthodb.org/?gene=A0A8V0ZUU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44281", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44281", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44281:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44281:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18594", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18594", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUT6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUU1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAELLFNCEVCVQVRSQACEERRLNVRVNVELLSISNPVHKKDLAVRLTDDADPFFLYNLVISEEDFQSLKSQQGLLVDFSAFPQKFIDLLQQCIQEQNKDIPRFLLQLVYSGSVLDHTPVSLNVVETNPFKHLTHLSLKFLPGNDAEIKKFLARCLKCLKEDKMTLEDKLRKTEEDFTRQLSYTQQSLSEKSRELDKLKNEWTSYTAALTSKHTQELTAEKERALQAQTQYQQQHEQQKKELESLHQRSIQQLQNRLSELEVINKDLTERRYKGDSTVRELKAKLSGVEDECQRAKQEVVSLRRENTTLDAECHEKEKFINQLQTRVAVLEQEIKDKDQLVIRTKEVLDATQEQKVILEENTEKKQSHIEKLETTIKSLSAELLKANEIIKKLQGDLKTLMSKLKLKNTVTIQQEKLLAEKEERLQKEQRELQETGQSLRMKEQEVCKLQEQLETTIQKLEESKQLLKTNENVITWLNKQLNEVQMLKRMETPSSMHGGIRTALSPHGMLERPSFPSSGISHTISPFYAFQKFAEPAHNKNPSPHCPVPKIQFNSQVSKIDQHSDVQVVTAATGHPANKEKRRSQSSLFLLVTSLWLPAVITWGWNPSISRKKKIAFLYEGLSQNTLNSENLKPYLPKVQPSLPAAVTTTSAYFPG", "length": 658, "header": "tr|A0A8V0ZPL2-1|A0A8V0ZPL2_CHICK Isoform 1 of Spindle assembly abnormal protein 6 homolog OS=Gallus gallus OX=9031 GN=SASS6 PE=4 SV=1 CANONICAL=A0A8V0ZPL2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2/entry#A0A8V0ZPL2-1", "sequence": { "sequence": "MAAELLFNCEVCVQVRSQACEERRLNVRVNVELLSISNPVHKKDLAVRLTDDADPFFLYNLVISEEDFQSLKSQQGLLVDFSAFPQKFIDLLQQCIQEQNKDIPRFLLQLVYSGSVLDHTPVSLNVVETNPFKHLTHLSLKFLPGNDAEIKKFLARCLKCLKEDKMTLEDKLRKTEEDFTRQLSYTQQSLSEKSRELDKLKNEWTSYTAALTSKHTQELTAEKERALQAQTQYQQQHEQQKKELESLHQRSIQQLQNRLSELEVINKDLTERRYKGDSTVRELKAKLSGVEDECQRAKQEVVSLRRENTTLDAECHEKEKFINQLQTRVAVLEQEIKDKDQLVIRTKEVLDATQEQKVILEENTEKKQSHIEKLETTIKSLSAELLKANEIIKKLQGDLKTLMSKLKLKNTVTIQQEKLLAEKEERLQKEQRELQETGQSLRMKEQEVCKLQEQLETTIQKLEESKQLLKTNENVITWLNKQLNEVQMLKRMETPSSMHGGIRTALSPHGMLERPSFPSSGISHTISPFYAFQKFAEPAHNKNPSPHCPVPKIQFNSQVSKIDQHSDVQVVTAATGHPANKEKRRSQSSLFLLVTSLWLPAVITWGWNPSISRKKKIAFLYEGLSQNTLNSENLKPYLPKVQPSLPAAVTTTSAYFPG", "length": 658, "header": "tr|A0A8V0ZPL2-1|A0A8V0ZPL2_CHICK Isoform 1 of Spindle assembly abnormal protein 6 homolog OS=Gallus gallus OX=9031 GN=SASS6 PE=4 SV=1 CANONICAL=A0A8V0ZPL2-1" }, "locus": { "chromosome": "8", "start_pos": 11681933, "end_pos": 11670635, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058211.1", "url": "https://www.ensembl.org/id/ENSGALT00010058211.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035363.1", "url": "https://www.ensembl.org/id/ENSGALP00010035363.1" } ] } }, { "isoform_ac": "A0A8V0ZUT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2/entry#A0A8V0ZUT6-1", "sequence": { "sequence": "MAAELLFNCEVCVQVRSQACEERRLNVRVNVELLSISNPVHKKDLAVRLTDDADPFFLYNLVISEEDFQRQKFIDLLQQCIQEQNKDIPRFLLQLVYSGSVLDHTPVSLNVVETNPFKHLTHLSLKFLPGNDAEIKKFLARCLKCLKEDKMTLEDKLRKTEEDFTRQLSYTQQSLSEKSRELDKLKNEWTSYTAALTSKHTQELTAEKERALQAQTQYQQQHEQQKKELESLHQRSIQQLQNRLSELEVINKDLTERRYKGDSTVRELKAKLSGVEDECQRAKQEVVSLRRENTTLDAECHEKEKFINQLQTRVAVLEQEIKDKDQLVIRTKEVLDATQEQKVILEENTEKKQSHIEKLETTIKSLSAELLKANEIIKKLQGDLKTLMSKLKLKNTVTIQQEKLLAEKEERLQKEQRELQETGQSLRMKEQEVCKLQEQLETTIQKLEESKQLLKTNENVITWLNKQLNEVQMLKRMETPSSMHGGIRTALSPHGMLERPSFPSSGISHTISPFYAFQKFAEPAHNKNPSPHCPVPKHCLIGDSMLTVMLFKIQFNSQVSKIDQHSDVQVVTAATGHPANKENGDNLGLESKYFKKKEDSIPLRRA", "length": 606, "header": "tr|A0A8V0ZUT6-1|A0A8V0ZPL2_CHICK Computationally mapped isoform of Spindle assembly abnormal protein 6 homolog OS=Gallus gallus OX=9031 GN=SASS6 PE=4 SV=1 CANONICAL=A0A8V0ZPL2-1" }, "locus": { "chromosome": "8", "start_pos": 11681728, "end_pos": 11670635, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058205.1", "url": "https://www.ensembl.org/id/ENSGALT00010058205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035360.1", "url": "https://www.ensembl.org/id/ENSGALP00010035360.1" } ] } }, { "isoform_ac": "A0A8V0ZUU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2/entry#A0A8V0ZUU1-1", "sequence": { "sequence": "MAAELLFNCEVCVQVRSQACEERRLNVRVNVELLSISNPVHKKDLAVRLTDDADPFFLYNLVISEEDFQRQVKFLKSQQGLLVDFSAFPQKFIDLLQQCIQEQNKDIPRFLLQLVYSGSVLDHTPVSLNVVETNPFKHLTHLSLKFLPGNDAEIKKFLARCLKCLKEDKMTLEDKLRKTEEDFTRQLSYTQQSLSEKSRELDKLKNEWTSYTAALTSKHTQELTAEKERALQAQTQYQQQHEQQKKELESLHQRSIQQLQNRLSELEVINKDLTERRYKGDSTVRELKAKLSGVEDECQRAKQEVVSLRRENTTLDAECHEKEKFINQLQTRVAVLEQEIKDKDQLVIRTKEVLDATQEQKVILEENTEKKQSHIEKLETTIKSLSAELLKANEIIKKLQGDLKTLMSKLKLKNTVTIQQEKLLAEKEERLQKEQRELQETGQSLRMKEQEVCKLQEQLETTIQKLEESKQLLKTNENVITWLNKQLNEVQMLKRMETPSSMHGGIRTALSPHGMLERPSFPSSGISHTISPFYAFQKFAEPAHNKNPSPHCPVPKIQFNSQVSKIDQHSDVQVVTAATGHPANKENGDNLGLESKYFKKKEDSIPLRRA", "length": 610, "header": "tr|A0A8V0ZUU1-1|A0A8V0ZPL2_CHICK Computationally mapped isoform of Spindle assembly abnormal protein 6 homolog OS=Gallus gallus OX=9031 GN=SASS6 PE=4 SV=1 CANONICAL=A0A8V0ZPL2-1" }, "locus": { "chromosome": "8", "start_pos": 11681728, "end_pos": 11670635, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058214.1", "url": "https://www.ensembl.org/id/ENSGALT00010058214.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035365.1", "url": "https://www.ensembl.org/id/ENSGALP00010035365.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of centriole replication", "id": "GO:0046601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046601", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2" } ], "pmid": "" }, { "name": "positive regulation of G1/S transition of mitotic cell cycle", "id": "GO:1900087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2" } ], "pmid": "" }, { "name": "deuterosome", "id": "GO:0098536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPL2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPN1-1", "uniprot_ac": "A0A8V0ZPN1", "uniprot_id": "A0A8V0ZPN1_CHICK", "mass": { "chemical_mass": 53445.0, "monoisotopic_mass": 53445.0 }, "refseq": {}, "gene_names": [ { "name": "CUTC", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN1" } ] } ], "protein_names": [ { "name": "Copper homeostasis protein cutC homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role in copper homeostasis. Can bind one Cu(1+) per subunit.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZUT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT7#function" }, { "database": "UniProtKB", "id": "ARBA00055012", "url": "https://www.uniprot.org/uniprotkb/ARBA00055012#function" }, { "database": "UniProtKB", "id": "A0A8V0ZPN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CUTC", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN1", "locus": { "chromosome": "6", "start_pos": 22887011, "end_pos": 22891554, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022221", "url": "https://www.ensembl.org/id/ENSGALG00010022221" } ] } } ], "crossref": [ { "id": "A0A8V0ZPN1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR005627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPN1", "url": "https://www.orthodb.org/?gene=A0A8V0ZPN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZUT7", "url": "https://www.orthodb.org/?gene=A0A8V0ZUT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12598", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12598", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12598:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12598:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZPN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZUT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSLCCLSAGPAPPAHRPTSECSHFKLWELLVLLKLRFPLLLRPGGFHLLHQVPVHHGQAGFRQPAGRQKQHGSPQQNRDDSRWVQQTTLKLRARNMERREDRRPKQYGLAPPIPRPAEAGASAGRAPALTWSRRPALRHPPQRRCRRAAIARQRAGRRGPAAAGGRDAEADGEGRARGRDGRTARLRSTASAASRPSPEVAAAWRKWGERFRPPPGVTMTIPRHVTQNQQRPPRAASAGMDDGFLMEVCVDSVESAVNAERGGAGRIELCAGLVEGGTTPSMGLLQVVKQCVRVPVFVMIRPRGGDFLYSDREVEVMKADIRLAKLHGADGLVFGALTEDGRIDTELCTALLAVCRPLPVTFHRAFDMVHDPQVALETLISLGFERVLTSGCDSSALEGLSLIKKLAEQAKGRIVVVPGGGITERNLQRILEGSSASEFHCSARSARDSGMKFRNPNVAMGASFSAPEYSVKVADVAKVRTLNAIAKNIL", "length": 491, "header": "tr|A0A8V0ZPN1-1|A0A8V0ZPN1_CHICK Isoform 1 of Copper homeostasis protein cutC homolog OS=Gallus gallus OX=9031 GN=CUTC PE=3 SV=1 CANONICAL=A0A8V0ZPN1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN1/entry#A0A8V0ZPN1-1", "sequence": { "sequence": "MRSLCCLSAGPAPPAHRPTSECSHFKLWELLVLLKLRFPLLLRPGGFHLLHQVPVHHGQAGFRQPAGRQKQHGSPQQNRDDSRWVQQTTLKLRARNMERREDRRPKQYGLAPPIPRPAEAGASAGRAPALTWSRRPALRHPPQRRCRRAAIARQRAGRRGPAAAGGRDAEADGEGRARGRDGRTARLRSTASAASRPSPEVAAAWRKWGERFRPPPGVTMTIPRHVTQNQQRPPRAASAGMDDGFLMEVCVDSVESAVNAERGGAGRIELCAGLVEGGTTPSMGLLQVVKQCVRVPVFVMIRPRGGDFLYSDREVEVMKADIRLAKLHGADGLVFGALTEDGRIDTELCTALLAVCRPLPVTFHRAFDMVHDPQVALETLISLGFERVLTSGCDSSALEGLSLIKKLAEQAKGRIVVVPGGGITERNLQRILEGSSASEFHCSARSARDSGMKFRNPNVAMGASFSAPEYSVKVADVAKVRTLNAIAKNIL", "length": 491, "header": "tr|A0A8V0ZPN1-1|A0A8V0ZPN1_CHICK Isoform 1 of Copper homeostasis protein cutC homolog OS=Gallus gallus OX=9031 GN=CUTC PE=3 SV=1 CANONICAL=A0A8V0ZPN1-1" }, "locus": { "chromosome": "6", "start_pos": 22891355, "end_pos": 22887344, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054071.1", "url": "https://www.ensembl.org/id/ENSGALT00010054071.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032601.1", "url": "https://www.ensembl.org/id/ENSGALP00010032601.1" } ] } }, { "isoform_ac": "A0A8V0ZUT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN1/entry#A0A8V0ZUT7-1", "sequence": { "sequence": "MDDGFLMEVCVDSVESAVNAERGGAGRIELCAGLVEGGTTPSMGLLQVVKQCVRVPVFVMIRPRGGDFLYSDREVEVMKADIRLAKLHGADGLVFGALTEDGRIDTELCTALLAVCRPLPVTFHRAFDMVHDPQVALETLISLGFERVLTSGCDSSALEGLSLIKKLAEQVRGGITERNLQRILEGSSASEFHCSARSARDSGMKFRNPNVAMGASFSAPEYSVKVADVAKVRTLNAIAKNIL", "length": 243, "header": "tr|A0A8V0ZUT7-1|A0A8V0ZPN1_CHICK Computationally mapped isoform of Copper homeostasis protein cutC homolog OS=Gallus gallus OX=9031 GN=CUTC PE=3 SV=1 CANONICAL=A0A8V0ZPN1-1" }, "locus": { "chromosome": "6", "start_pos": 22890349, "end_pos": 22887344, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054068.1", "url": "https://www.ensembl.org/id/ENSGALT00010054068.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032599.1", "url": "https://www.ensembl.org/id/ENSGALP00010032599.1" } ] } } ], 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"metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPQ0-1", "uniprot_ac": "A0A8V0ZPQ0", "uniprot_id": "A0A8V0ZPQ0_CHICK", "mass": { "chemical_mass": 299247.0, "monoisotopic_mass": 299247.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Mucin 2, oligomeric mucus/gel-forming", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0", "locus": {} } ], "crossref": [ { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339:SF371", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339:SF371", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13330", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13330", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25962", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25962", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZPQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZX81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZX81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYR2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2F1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2F1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A2P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2P6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VELTWTHLSSALCRYSIRLEICGVTMGVIANGFCILQHLTLLDSSSFISLSSLFLFHNLTGRTRNHGHYVCSTWGNNHFKTFDGDIYQFPGMCEYNFVSDCQDSYREFSVHIQRALNSNNHPEIQYILITVTDFTVYLKPKLAVVDGRIVKTPYYSSGLLIESNDIYTKVYAKLGLILIWNQEDALMVELDSKFGNQTCGLCGDYNGVPIYNEFISGVASYNSITYGNLQKISKPNDECEDPDETRALPSCNEHREECEKLLTSSAFADCHSRLNLEMYIQACMQDKCACKGNEDSFCLCSTISEYSRQCSHAGGRPGEWRTENFCYKTCPGNMVYRESSSPCMDTCSHLEVSSLCEEHYMDGCFCPEGTVYDDITENGCIPVSQCSCRLHGKGYSPGETITNECEECTCDSGRWTCKDLPCPGTCSVEGGSHIKTFDGKKYTFHGDCYYVLAKSAVNDTHALLAELAPCGSSDGQTCLKTVVLLVDDKKNVVVFRSDGSVSLNEMTVNVPHVSASFSVFKPSSYYLIVHTSFGLQLQIQLSPVMQLFVTADQSVQDIQGLCGNFNGMEGDDFKTTNGLVEATGSAFANTWKAQPTCADQAEKLEDPCTLSIESANYAEHWCSLLKNSEGPFARCHSVIDPAEYYKRCKYDTCLCKDNEECLCAALSSYSRACAFKGIILGGWRQSVCSDEVSACPGNQVFLYNLTMCQQTCRSIADGEKYCLQDFAPVDGCGCPDNTYLDNQDTCVPISKCPCYYKGSYLEPGEYVTKDGERWYKNLVLFPKVPIFLYEEDCPCIHNSDWYNHGQSITVDCNTCTCQKGIWSCTKNVCYGTCMIYGSGHYITFDGKFYDFDGSCEYVATQDYCGDKNSGGSFSIITENVPCGTTGVTCSKAIKMFIGKTELKLENKDYKEIQRDVGDDVHYQNKTVGLYLVIEASNGVMLIWDKKTTVFIKLTPDYKGKVCGLCGNFDDKANNDFTSRNGLQETNALTFGNSWKQSSVCPDVTEEIKPCDLKPHRKSWAEKECSLILSEIFKICHSKVNPSPFYDACVHDACSCDSGGDCDCFCSAVAAYAQECTKAQACVFWRSPDICPIFCDYYNPRNECEWHYEPCGSNVMTCRMLYNVSTNFSVPYLEGCYPRCPHEKPVYNEETKECVAADECWCYHNGKPVIIGCPCVINGTSYEVGQTVATIKDGDICTTYVCAENGSVVPGSTYPCPLTTSPSTITTSPGTSTLTTIGKFSTEISDTEPMSFLAAPCLVLICDWSEWFDVSNPEEDGGDYETYDAIRIEHGNKICAAPENIECRAKDSPDKTLEELGQKVECNVTYGLICKNEEQDASIWHLCYNYEIRVNCCEWHEIPCDAGPSSTPTASSVTTGTTVPTTTTQQSTTITTIPTPTATTTSHTPVSHSTTTTIVFTSTVSSTAATTTPTGSAPTTTSGTMPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPRPTPTTSVTRPPTPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVTTSTPGPTPTTSVTPPPTTTEGNVWSSHYVSPLVCTFPPEDCIWTDWIDVSYPQFGPEGGDDETFETIQNKIPSWNCTKVENVSCRAEKFPDIPIEDLGQKVECDVNTGLICKNKDQTTGGVIPMPVCLNYQIKVCCAPPLSPECTTAVTTTTTGETSTTVSLSPTTSTRYTPSVSSTTSPPTPTGAPPTPTGSSPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPGPTPTTSVTRPPTSTEGNCLAVVPLVCTFPPEDCIWTDWIDVSYPWFGPEGGDDETFETIQNKIPSWNCTKVENVSCRAEKFPDIPIEDLGQKVECDVNTGLICKNKDQTTGGVIPMPVCLNYQIKVCCAPPLSPECTTAVTTTTTGETSTTVSLSPTTSTRYTPSVSSTTSPPTPTGSAPTTTSGTTPSSISTVPSTVTTSGTTPTKPFTTTSGTTSSSFSTVTATTITTSEIVSSGSASTSGTTPASSTVTVSGSSTYSTLTTLSTLSSTASSSSNCTISPNETHAVSEFNYVYFYYCINVSSLTQSDCFIRLSFFLSFFLTSFQIQPGESWWLCNCTKAICVENNTVVIVPVICEPPPKPTCSNGLAPVQVIDDDLCCWHWECDCYCTGWGDPHYMTFDGLYYSYQGNCTYVLVEEIEKRVDNFGVYIDNYHCDARDIVSCPRALIVRHETQEVRIVTVKPNTLEVEVTVNKQPVALPYKKFGLSVYESGINRVVEIPELKMNVSFNGLSFSIRMPYSLFGNNTQGQCGICNNNTADDCRLPNGNIAENCETMADYWQVVDPSKPQCSPGLVPTKAPSTTTGKPCKESSLCELLWGSVFEKCREVVKPDKYYAACVFDSCTLPDLDLECSSLQIYAAICADQNVCVDWRSHTNGVCCKYLAIYHELFSSEHFVSYSPQNETSIKQIEGCFCPNGTMLFDSGVDVCVNTCGEFYYFTWFGEKFTADCQDCVCLEGGNGIVCEPHKCPEQNKKSCSGKGFYEVTVVNSEDPCCPTVTCKCNTSLCTTEPPKCTLGFEVFSYIPSDECCPVYKCVFVDKCHNCFCTNEVNISTQLNVISCERIPCNTYCEPGYELQHVQGECCGKCVQTKCVIHTSHSSNLILNVSMLYVLPLYKIYKLSLLKDEALCNFASEMSATYLEYSVEASSMEHSCSCCKEVETSMKEVELKCPSGHSITHKYVYVESCGCQDTQCISTQNHKRRAISLTSK", "length": 2740, "header": "tr|A0A8V0ZPQ0-1|A0A8V0ZPQ0_CHICK Isoform 1 of Mucin 2, oligomeric mucus/gel-forming OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZPQ0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0/entry#A0A8V0ZPQ0-1", "sequence": { "sequence": "VELTWTHLSSALCRYSIRLEICGVTMGVIANGFCILQHLTLLDSSSFISLSSLFLFHNLTGRTRNHGHYVCSTWGNNHFKTFDGDIYQFPGMCEYNFVSDCQDSYREFSVHIQRALNSNNHPEIQYILITVTDFTVYLKPKLAVVDGRIVKTPYYSSGLLIESNDIYTKVYAKLGLILIWNQEDALMVELDSKFGNQTCGLCGDYNGVPIYNEFISGVASYNSITYGNLQKISKPNDECEDPDETRALPSCNEHREECEKLLTSSAFADCHSRLNLEMYIQACMQDKCACKGNEDSFCLCSTISEYSRQCSHAGGRPGEWRTENFCYKTCPGNMVYRESSSPCMDTCSHLEVSSLCEEHYMDGCFCPEGTVYDDITENGCIPVSQCSCRLHGKGYSPGETITNECEECTCDSGRWTCKDLPCPGTCSVEGGSHIKTFDGKKYTFHGDCYYVLAKSAVNDTHALLAELAPCGSSDGQTCLKTVVLLVDDKKNVVVFRSDGSVSLNEMTVNVPHVSASFSVFKPSSYYLIVHTSFGLQLQIQLSPVMQLFVTADQSVQDIQGLCGNFNGMEGDDFKTTNGLVEATGSAFANTWKAQPTCADQAEKLEDPCTLSIESANYAEHWCSLLKNSEGPFARCHSVIDPAEYYKRCKYDTCLCKDNEECLCAALSSYSRACAFKGIILGGWRQSVCSDEVSACPGNQVFLYNLTMCQQTCRSIADGEKYCLQDFAPVDGCGCPDNTYLDNQDTCVPISKCPCYYKGSYLEPGEYVTKDGERWYKNLVLFPKVPIFLYEEDCPCIHNSDWYNHGQSITVDCNTCTCQKGIWSCTKNVCYGTCMIYGSGHYITFDGKFYDFDGSCEYVATQDYCGDKNSGGSFSIITENVPCGTTGVTCSKAIKMFIGKTELKLENKDYKEIQRDVGDDVHYQNKTVGLYLVIEASNGVMLIWDKKTTVFIKLTPDYKGKVCGLCGNFDDKANNDFTSRNGLQETNALTFGNSWKQSSVCPDVTEEIKPCDLKPHRKSWAEKECSLILSEIFKICHSKVNPSPFYDACVHDACSCDSGGDCDCFCSAVAAYAQECTKAQACVFWRSPDICPIFCDYYNPRNECEWHYEPCGSNVMTCRMLYNVSTNFSVPYLEGCYPRCPHEKPVYNEETKECVAADECWCYHNGKPVIIGCPCVINGTSYEVGQTVATIKDGDICTTYVCAENGSVVPGSTYPCPLTTSPSTITTSPGTSTLTTIGKFSTEISDTEPMSFLAAPCLVLICDWSEWFDVSNPEEDGGDYETYDAIRIEHGNKICAAPENIECRAKDSPDKTLEELGQKVECNVTYGLICKNEEQDASIWHLCYNYEIRVNCCEWHEIPCDAGPSSTPTASSVTTGTTVPTTTTQQSTTITTIPTPTATTTSHTPVSHSTTTTIVFTSTVSSTAATTTPTGSAPTTTSGTMPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPRPTPTTSVTRPPTPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVTTSTPGPTPTTSVTPPPTTTEGNVWSSHYVSPLVCTFPPEDCIWTDWIDVSYPQFGPEGGDDETFETIQNKIPSWNCTKVENVSCRAEKFPDIPIEDLGQKVECDVNTGLICKNKDQTTGGVIPMPVCLNYQIKVCCAPPLSPECTTAVTTTTTGETSTTVSLSPTTSTRYTPSVSSTTSPPTPTGAPPTPTGSSPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPGPTPTTSVTRPPTSTEGNCLAVVPLVCTFPPEDCIWTDWIDVSYPWFGPEGGDDETFETIQNKIPSWNCTKVENVSCRAEKFPDIPIEDLGQKVECDVNTGLICKNKDQTTGGVIPMPVCLNYQIKVCCAPPLSPECTTAVTTTTTGETSTTVSLSPTTSTRYTPSVSSTTSPPTPTGSAPTTTSGTTPSSISTVPSTVTTSGTTPTKPFTTTSGTTSSSFSTVTATTITTSEIVSSGSASTSGTTPASSTVTVSGSSTYSTLTTLSTLSSTASSSSNCTISPNETHAVSEFNYVYFYYCINVSSLTQSDCFIRLSFFLSFFLTSFQIQPGESWWLCNCTKAICVENNTVVIVPVICEPPPKPTCSNGLAPVQVIDDDLCCWHWECDCYCTGWGDPHYMTFDGLYYSYQGNCTYVLVEEIEKRVDNFGVYIDNYHCDARDIVSCPRALIVRHETQEVRIVTVKPNTLEVEVTVNKQPVALPYKKFGLSVYESGINRVVEIPELKMNVSFNGLSFSIRMPYSLFGNNTQGQCGICNNNTADDCRLPNGNIAENCETMADYWQVVDPSKPQCSPGLVPTKAPSTTTGKPCKESSLCELLWGSVFEKCREVVKPDKYYAACVFDSCTLPDLDLECSSLQIYAAICADQNVCVDWRSHTNGVCCKYLAIYHELFSSEHFVSYSPQNETSIKQIEGCFCPNGTMLFDSGVDVCVNTCGEFYYFTWFGEKFTADCQDCVCLEGGNGIVCEPHKCPEQNKKSCSGKGFYEVTVVNSEDPCCPTVTCKCNTSLCTTEPPKCTLGFEVFSYIPSDECCPVYKCVFVDKCHNCFCTNEVNISTQLNVISCERIPCNTYCEPGYELQHVQGECCGKCVQTKCVIHTSHSSNLILNVSMLYVLPLYKIYKLSLLKDEALCNFASEMSATYLEYSVEASSMEHSCSCCKEVETSMKEVELKCPSGHSITHKYVYVESCGCQDTQCISTQNHKRRAISLTSK", "length": 2740, "header": "tr|A0A8V0ZPQ0-1|A0A8V0ZPQ0_CHICK Isoform 1 of Mucin 2, oligomeric mucus/gel-forming OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZPQ0-1" }, "locus": { "chromosome": "5", "start_pos": 14602158, "end_pos": 14528006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058281.1", "url": "https://www.ensembl.org/id/ENSGALT00010058281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035405.1", "url": "https://www.ensembl.org/id/ENSGALP00010035405.1" } ] } }, { "isoform_ac": "A0A8V0ZX22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0/entry#A0A8V0ZX22-1", "sequence": { "sequence": "MGVIANGFCILQHLTLLDSSSFISLSSLFLFHNLTGRTRNHGHYVCSTWGNNHFKTFDGDIYQFPGMCEYNFVSDCQDSYREFSVHIQRALNSNNHPEIQYILITVTDFTVYLKPKLAVVDGRIVKTPYYSSGLLIESNDIYTKVYAKLGLILIWNQEDALMVELDSKFGNQTCGLCGDYNGVPIYNEFISGGDYNSITYGNLQKISKPNDECEDPDETRALPSCNEHREECEKLLTSSAFADCHSRLNLEMYIQACMQDKCACKGNEDSFCLCSTISEYSRQCSHAGGRPGEWRTENFCYKTCPGNMVYRESSSPCMDTCSHLEVSSLCEEHYMDGCFCPEGTVYDDITENGCIPVSQCSCRLHGKGYSPGETITNECEECTCDSGRWTCKDLPCPGTCSVEGGSHIKTFDGKKYTFHGDCYYVLAKSAVNDTHALLAELAPCGSSDGQTCLKTVVLLVDDKKNVVVFRSDGSVSLNEMTVNVPHVSASFSVFKPSSYYLIVHTSFGLQLQIQLSPVMQLFVTADQSVQDIQGLCGNFNGMEGDDFKTTNGLVEATGSAFANTWKAQPTCADQAEKLEDPCTLSIESANYAEHWCSLLKNSEGPFARCHSVIDPAEYYKRCKYDTCLCKDNEECLCAALSSYSRACAFKGIILGGWRQTDEVSACPGNQVFLYNLTMCQQTCRSIADGEKYCLQDFAPVDGCGCPDNTYLDNQDTCVPISKCPCYYKGSYLEPGEYVTKDGERWYVLLHRPVCITECPSNKTYFDCNASPDWTSRTPVQLRCVCPEGLFDDGRGGCVEEEDCPCIHNSDWYNHGQSITVDCNTCTCQKGIWSCTKNVCYGTCMIYGSGHYITFDGKFYDFDGSCEYVATQVIIITENVPCGTTGVTCSKAIKMFIGKTELKLENKDYKEIQRDVGDDVHYQNKTVGLYLVIEASNGVMLIWDKKTTVFIKLTPDYKGKVCGLCGNFDDKANNDFTSRNGLQETNALTFGNSWKQSSVCPDVTEEIKPCDLKPHRKSWAEKECSLILSEIFKICHSKVNPSPFYDACVHDACSCDSGGDCDCFCSAVAAYAQECTKAQACVFWRSPDICPIFCDYYNPRNECEWHYEPCGSNVMTCRMLYNVSTNFSVPYLEGCYPRCPHEKPVYNEETKECVAADECWCYHNGKPVIIVNMHAELFLAGCPCVINGTSYEVGQTVATIKDGDICTTYVCAENGSVVPGSTYPCPLTTSPSTITTSPGTSTLTTIGNSDTEPMSFLAAPCLVLICDWSEWFDVSNPEEDGGDYETYDAIRIEHGNKICAAPENIECRAKDSPDKTLEELGQKVECNVTYGLICKNEEQDASIWHLCYNYEIRVNCCECPECTTAVTTTTTGETSTTVTTSPPTPTGSAPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPGPTPTTSVTRPPTSTEGPTSQSTTSTTVSSPSVSSSSAPPTPTGSSPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPGPTPTTSVTRPPTSTEGNCLAVVPLVCTFPPEDCIWTDWIDVSYPWFGPEGGDDETFETIQNKIPSWNCTKVENVSCRAEKFPDIPIEDLGQKVECDVNTGLICKNKDQTTGGVIPMPVCLNYQIKVCCAPPLSPECTTAVTTTTTGETSTTVSLSPTTSTRYTPSVSSTTSPPTPTGREIMKGSGNAICLLAMMKPCVFPGPTSQSTTSTTVSSPSVSSSSAPPTPTGSSPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPGPTPTTSVTRPPTSTEGNCLAVVPRVPLLRERYSGINVSSLTQSDCFIRLSFFLSFFLTSFQIQPGESWWLCNCTKAICVENNTVVIVPVICEPPPKPTCSNGLAPVQVIDDDLCCWHWECDCYCTGWGDPHYMTFDGLYYSYQGNCTYVLVEEIEKRVDNFGVYIDNYHCDARDIVSCPRALIVRHETQEVRIVTVKPNTLEVTVNKQPVALPYKKFGLSVYESGINRVVEIPELKMNVSFNGLSFSIRMPYSLFGNNTQGQCGICNNNTADDCRLPNGNIAENCETMADYWQVVDPSKPQCSPGLVPTKAPSTTTGKPCKESSLCELLWGSVFEKCREVVKPDKYYAACVFDSCTLPDLDLECSSLQIYAAICADQNVCVDWRSHTNGVCSYECPKHKEYRACGPIQETTCKSSPQNETSIKQIEGCFCPNGTMLFDSGVDVCVNTCGCVGLDMIPREFGEKFTADCQDCVCLEGGNGIVCEPHKCPEQNKKSCSGKGFYEVTVVNSEDPCCPTVTCKCNTSLCTTEPPKCTLGFEVFSYIPSDECCPVYKCVFVDKCHNCFCTNEVNISTQLNVISCERIPCNTYCEPGYELQHVQGECCGKCVQTKCVIHTSHSSNLILNVSMLYVLPLYKIYKLSLLKDEALCNFASEMSATYLEYSVEASSMEHSCSCCKEVETSMKEVELKCPSGHSITHKYVYVESCGCQDTQCIVPESNLAWKILSGGPKVDYAC", "length": 2516, "header": "tr|A0A8V0ZX22-1|A0A8V0ZPQ0_CHICK Computationally mapped isoform of Mucin 2, oligomeric mucus/gel-forming OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZPQ0-1" }, "locus": { "chromosome": "5", "start_pos": 14601833, "end_pos": 14527551, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058326.1", "url": "https://www.ensembl.org/id/ENSGALT00010058326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035435.1", "url": "https://www.ensembl.org/id/ENSGALP00010035435.1" } ] } }, { "isoform_ac": "A0A8V0ZX81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0/entry#A0A8V0ZX81-1", "sequence": { "sequence": "MQHLDIYRGWGGNELQSIRRTRNHGHYVCSTWGNNHFKTFDGDIYQFPGMCEYNFVSDCQDSYREFSVHIQRALNSNNHPEIQYILITVTDFTVYLKPKLAVVDGRIVKTPYYSSGLLIESNDIYTKVYAKLGLILIWNQEDALMVELDSKFGNQTCGLCGDYNGVPIYNEFISGVASYNSITYGNLQKISKPNDECEDPDETRALPSCNEHREECEKLLTSSAFADCHSRLNLEMYIQACMQDKCACKGNEDSFCLCSTISEYSRQCSHAGGRPGEWRTENFCYKTCPGNMVYRESSSPCMDTCSHLEVSSLCEEHYMDGCFCPEGTVYDDITENGCIPVSQCSCRLHGKGYSPGETITNECEECTCDSGRWTCKDLPCPGTCSVEGGSHIKTFDGKKYTFHGDCYYVLAKSAVNDTHALLAELAPCGSSDGQTCLKTVVLLVDDKKNVVVFRSDGSVSLNEMTVNVPHVSASFSVFKPSSYYLIVHTSFGLQLQIQLSPVMQLFVTADQSVQDIQGLCGNFNGMEGDDFKTTNGLVEATGSAFANTWKAQPTCADQAEKLEDPCTLSIESANYAEHWCSLLKNSEGPFARCHSVIDPAEYYKRCKYDTCLCKDNEECLCAALSSYSRACAFKGIILGGWRQSVCSDEVSACPGNQVFLYNLTMCQQTCRSIADGEKYCLQDFAPVDGCGCPDNTYLDNQDTCVPISKCPCYYKGSYLEPGEYVTKDGERWYVLLHRITECPSNKTYFDCNASPDWTSRTPVQLRCGTSQTDLYQGECVSGCVCPEGLFDDGRGGCVEEEDCPCIHNSDWYNHGQSITVDCNTCTCQKGIWSCTKNVCYGTCMIYGSGHYITFDGKFYDFDGSCEYVATQDYCGDKNSGGSFSIITENVPCGTTGVTCSKAIKMFIGKTELKLENKDYKEIQRDVGDDVHYQNKTVGLYLVIEASNGVMLIWDKKTTVFIKLTPDYKGKVCGLCGNFDDKANNDFTSRNGLQETNALTFGNSWKQSSVCPDVTEEIKPCDLKPHRKSWAEKECSLILSEIFKICHSKVNPSPFYDACVHDACSCDSGGDCDCFCSAVAAYAQECTKAQACVFWRSPDICPIFCDYYNPRNECEWHYEPCGSNVMTCRMLYNVSTNFSVPYLEGCYPRCPHEKPVYNEETKECVAADECWCYHNGKPVIIGGEIPTEENCTKWYVKIYEVGQTVATIKDGDICTTYVCAENGSVVPGSTYPCPLTTSPSTITTSPGTSTLTTIGKFSTEISDTEPMSFLAWFDVSNPEEDGGDYETYDAIRIEHGNKICAAPENIECRAKDSPDKTLEELGQKVECNVTYGLICKNEEQDASIWHLCYNYEIRVNCCEWHEIPCDAGPSSTPTASSVTTGTTVPTTTTQQSTTITTIPTPTATTTIFTSTVSSTAATTTPTGSAPTTTSGTMPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPRPTPTTSVTRPPTSTEGNCLAVVPRKVECDVNTGLICKNKDQTTGGVIPMPVCLNYQIKVCCAPPLSPECTTAVTTTTTGETSTTVSLSPTTSTRYTPSVSSTTSPPTPTGSAPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPGPTPTTSVTRPPTSTEGNCLAVVPVSDCIWTDWIDVSYPWFGPEGGDDETFETIQNKIPSWNCTKVENVSCRAEKFPDIPIEDLGQKVECDVNTGLICKNKDQTTGGVIPMPVCLNYQIKVCCAPPLSPECTTAVTTTTTGETSTTVSLSPTTSTRYTPSVSSTTSPPTPTGSSTASVSTPVNTQSTGASSPLLTPSGSMSPPSVSTVPSTVTTSGTTPTKPFTTTSGTTSSSFSTVTATTITTSEIVSSGSASTSGTTPASSTVTVSGSSTYSTLTTLSTLSSTASSSSNCTISPNETHAVSEFNYVYFYYCINVSSLTQSDCFIRLSFFLSFFLTSFQIQPGESWWLCNCTKAICVENNTVVIVPVICEPPPKPTCSNGLAPVQVIDDDLCCWHWECDCYCTGWGDPHYMTFDGLYYSYQGNCTYVLVEEIEKRVDNFGVYIDNYHCDARDIVSCPRALIVRHETQEVLILKVFFEFFFLLPILGICNNNTADDCRLPNGNIAENCETMADYWQVVDPSKPQCSPGLVPTKAPSTTTGKPCKESSLCELLWGSVFEKCREVVKPDKYYAACVFDSCTLPDLDLECSSLQIYAAICADQNVCVDWRSHTNGVCCKYLAIYHELPQNETSIKQIEGCFCPNGTMLFDSGVDVCVNTCGEFYYFTWFGEKFTADCQDCVCLEGGNGIVCEPHKCPEQNKKSCSGKGFYEVTVVNSEDPCCPTVTCKCNTSLCTTEPPKCTLGFEVFSYIPSDECCPVYKCVFVDKCHNCFCTNEVNISTQLNVISCERIPCNTYCEPGYELQHVQGECCGKCVQTKCVIHTSHSSNLILNPGEFINDPYNNCTIYSCTSIKNQLISSTSEITCPAFNEESCKPGTVTFLPNGCCKTCKYVGVPELTIQKMNLILKSAHFIMYSVEASSMEHSCSCCKEVETSMKEVELKCPSGHSITHKYVYVESCGCQDTQCIVPESSERYPKEINWTAF", "length": 2595, "header": "tr|A0A8V0ZX81-1|A0A8V0ZPQ0_CHICK Computationally mapped isoform of Mucin 2, oligomeric mucus/gel-forming OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZPQ0-1" }, "locus": { "chromosome": "5", "start_pos": 14602314, "end_pos": 14527192, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058415.1", "url": "https://www.ensembl.org/id/ENSGALT00010058415.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035496.1", "url": "https://www.ensembl.org/id/ENSGALP00010035496.1" } ] } }, { "isoform_ac": "A0A8V0ZYR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0/entry#A0A8V0ZYR2-1", "sequence": { "sequence": "ALSFISLSSLFLFHNLTGRTRNHGHYVCSTWGNNHFKTFDGDIYQFPGMCEYNFVSDCQDSYREFSVHIQRALNSNNHPEIQYILITVTDFTVYLKPKLAVVDGRIVKTPYYSSGLLIESNDIYTKVYAKLGLILIWNQEDALMVELDSKFGNQTCGLCGDYNGVPIYNEFISGGESYIYNSITYGNLQKISKPNDECEDPDETRALPSCNEHREECEKLLTSSAFADCHSRLNLEMYIQACMQDKCACKGNEDSFCLCSTISEYSRQCSHAGGRPGEWRTENFCYKTCPGNMVYRESSSPCMDTCSHLEVSSLCEEHYMDGCFCPEGTVYDDITENGCIPVSQCSCRLHGKGYSPGETITNECEECTCDSGRWTCKDLPCPGTCSVEGGSHIKTFDGKKYTFHGDCYYVLAKSAVNDTHALLAELAPCGSSDGQTCLKTVVLLVDDKKNVVVFRSDGSVSLNEMTVNVPHVSASFSVFKPSSYYLIVHTSFGLQLQIQLSPVMQLFVTADQSVQDIQGLCGNFNGMEGDDFKTTNGLVEATGSAFANTWKAQPTCADQAEKLEDPCTLSIESANYAEHWCSLLKNSEGPFARCHSVIDPAEYYKRCKYDTCLCKDNEECLCAALSSYSRACAFKGIILGGWRQSVCSDEVSACPGNQVFLYNLTMCQQTCRSIADGEKYCLQDFAPVDGCGCPDNTYLDNQDTCVPISKCPCYYKGSYLEPGEYVTKDGERCVCRNAKIRCTSVTMRMKSECVSGCVCPEGLFDDGRGGCVEEEDCPCIHNSDWYNHGQSITVDCNTCTCQKGIWSCTKNVCYGTCMIYGSGHYITFDGKFYDFDGSCEYVATQDYCGDKNSGGSFSIITENVPCGTTGVTCSKAIKMFIGKTELKLENKDYKEIQRDVGDDVHYQNKTVGLYLVIEASNGVMLIWDKKTTVFIKLTPDYKGKVCGLCGNFDDKANNDFTSRNGLQETNALTFGNSWKQSSVCPDVTEEIKPCDLKPHRKSWAEKECSLILSEIFKICHSKVNPSPFYDACVHDACSCDSGGDCDCFCSAVAAYAQECTKAQACVFWRSPDICPIFCDYYNPRNECEWHYEPCGSNVMTCRMLYNVSTNFSVPYLEGCYPRCPHEKPVYNEETKECVAADECWCYHNGKPVIIGGEIPTEENCTKWYVKIYEVGQTVATIKDGDICTTYVCAENGSVVPGSTYPCPLTTSPSTITTSPGTSTLTTIGNSDTEPMSFLAAPCLVLICDWSEWFDVSNPEEDGGDYETYDAIRIEHGNKICAAPENIECRAKDSPDKTLEELGQKVECNVTYGLICKNEEQDASIWHLCYNYEIRVNCCEWHEIPCDAGPKCIPSTELVTTISTPVSHSTTTTIVFTSTVSSTAATTTPTGSAPTTTSGTMPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPRPTPTTSVTRPPTSTEGNCLAVVPRNKIPSWNCTKVENVSCRAEKFPDIPIEDLGQKVECDVNTGLICKNKDQTTGGVIPMPVCLNYQIKVCCAPPLSPECTTAVTTTTTGETSTTVSLSPTTSTRYTPSVSSTTSPPTPTGSAPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPGPTPTTSVTRPPTSTEGNLVCTFPPEDCIWTDWIDVSYPWFGPEGGDDETFETIQNKIPSWNCTKVENVSCRAEKFPDIPIEDLGQKVECDVNTGLICKNKDQTTGGVIPMPVCLNYQIKVCCAPPLSPECTTAVTTTTTGETSTTVSLSPTTSTRYTPSVSSTTSPPTPTGSQVLTVKLFFFSGTSSYSTTILTGSFSTEGTTTVSESSSTASVSTPVNTQSTGASSPLLTPSGSMSPPSVSTVPSTVTTSGTTPTKPFTTTSGTTSSSFSTVTATTITTSEIVSSGSASTSGTTPASSTVTVSGSSTYSTLTTLSTLSSTASSSSNCTISPNETHAVSEFNYVYFYYCINVSSLTQSDCFIRLSFFLSFFLTSFQIQPGESWWLCNCTKAICVENNTVVIVPVICEPPPKPTCSNGLAPVQVIDDDLCCWHWECDCYCTGWGDPHYMTFDGLYYSYQGNCTYVLVEEIEKRVDNFGVYIDNYHCDARDIVSCPRALIVRHETQEVRIVTVKPNTLEVEVTVNKQPVALPYKKFGLSVYESGINRVVEIPELKMNVSFNGLSFSIRMPYSLFGNNTQGQCGICNNNTADDCRLPNGNIAENCETMADYWQVVDPSKPQCSPGLVPTKAPSTTTGNMMYVSVFSVFEKCREVVKPDKYYAACVFDSCTLPDLDLECSSLQIYAAICADQNVCVDWRSHTNGVCCKYLAIYHELFSSEHFVSYSPQNETSIKQIEGCFCPNGTMLFDSGVDVCVNTCGEFYYFTWFGEKFTADCQDCVCLEGGNGIVCEPHKCPEQNKKSCSGKGFYEVTVVNSEDPCCPTVTCKCNTSLCTTEPPKCTLGFEVFSYIPSDECCPVYKCVFVDKCHNCFCTNEVNISTQLNVISCERIPCNTYCEPGYELQHVQGECCGKCVQTKCVIHTSHSSNLILNPGEFINDPYNNCTIYSCTSIKNQLISSTSEITCPAFNEESCKPGTVTFLPNGCCKTCKYVGVPELTIQKMNLILKSAHFIMYSVEASSMEHSCSCCKEVETSMKEVELKCPSGHSITHKYVYVESCGCQDTQCIVPESSESQSTEENDESTQNHKRRAISLTSK", "length": 2706, "header": "tr|A0A8V0ZYR2-1|A0A8V0ZPQ0_CHICK Computationally mapped isoform of Mucin 2, oligomeric mucus/gel-forming OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZPQ0-1" }, "locus": { "chromosome": "5", "start_pos": 14602340, "end_pos": 14528006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058358.1", "url": "https://www.ensembl.org/id/ENSGALT00010058358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035460.1", "url": "https://www.ensembl.org/id/ENSGALP00010035460.1" } ] } }, { "isoform_ac": "A0A8V1A2F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0/entry#A0A8V1A2F1-1", "sequence": { "sequence": "VELTWTHLSSALCRYSIRLEICGVTMGVIANGFCILQHLTLLDSSSFISLSSLFLFHNLTGRTRNHGHYVCSTWGNNHFKTFDGDIYQFPGMCEYNFVSDCQDSYREFSVHIQRALNSNNHPEIQYILITVTDFTVYLKPKLAVVDGRIVKTPYYSSGLLIESNDIYTKVYAKLGLILIWNQEDALMVELDSKFGNQTCGLCGDYNGVPIYNEFISGVASYNSITYGNLQKISKPNDECEDPDETRALPSCNEHREECEKLLTSSAFADCHSRLNLEMYIQACMQDKCACKGNEDSFCLCSTISEYSRQCSHAGGRPGEWRTENFCYKTCPGNMVYRESSSPCMDTCSHLEVSSLCEEHYMDGCFCPEGTVYDDITENGCIPVSQCSCRLHGKGYSPGETITNECEECTCDSGRWTCKDLPCPGTCSVEGGSHIKTFDGKKYTFHGDCYYVLAKSAVNDTHALLAELAPCGSSDGQTCLKTVVLLVDDKKNVVVFRSDGSVSLNEMTVNVPHVSASFSVFKPSSYYLIVHTSFGLQLQIQLSPVMQLFVTADQSVQDIQGLCGNFNGMEGDDFKTTNGLVEATGSAFANTWKAQPTCADQAEKLEDPCTLSIESGKLANKTNVGSCQEECKYDTCLCKDNEECLCAALSSYSRACAFKGIILGGWRQSVCSDEVSACPGNQVFLYNLTMCQQTCRSIADGEKYCLQDFAPVDGCGCPDNTYLDNQDTCVPISKCPCYYKGSYLEPGEYVTKDGERWYKNLVLFPKVPIFLYEEDCPCIHNSDWYNHGQSITVDCNTCTCQKGIWSCTKNVCYGTCMIYGSGHYITFDGKFYDFDGSCEYVATQDYCGDKNSGGSFSIITENVPCGTTGVTCSKAIKMFIGKTELKLENKDYKEIQRDVGDDVHYQNKTVGLYLVIEASNGVMLIWDKKTTVFIKLTPDYKGKVCGLCGNFDDKANNDFTSRNGLQETNALTFGNSWKQSSVCPDVTEEIKPCDLKPHRKSWAEKECSLILSEIFKICHSKVNPSPFYDACVHDACSCDSGGDCDCFCSAVAAYAQECTKAQACVFWRSPDICPIFCDYYNPRNECEWHYEPCGSNVMTCRMLYNVSTNFSVPYLEGCYPRCPHEKPVYNEETKECVAADECWCYHNGKPVIIGCPCVINGTSYEVGQTVATIKDGDICTTYVCAENGSVVPGSTYPCPLTTSPSTITTSPGTKCLLSSDTEPMSFLAAPCLVLICDWSEWFDVSNPEEDGGDYETYDAIRIEHGNKICAAPENIECRAKDSPDKTLEELGQKVECNVTYGLICKNEEQDASIWHLCYNYEIRVNCCEWHEIPCDAGPSSTPTASSVTTGTTVPTTTTQQSTTITTIPTPTATTTSQSPPSVTSGSTVSTTAPTPTPSESPTSTTTTTPFSSSSQGATPTVPGVSSSIPTVTSTVLPPIVTQTHSPPPSQPVGNCECTWTDWIDSSQPDRSDVNSGDYETIDKINNSSFVCVKAENISCRAKDYPNISLEELGQKVECSVNTGLICNNKDQENNGHVSYCHNYEINVCCTPNKPECIPSTELVTTISTPVSHSTTTTIVFTSTVPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVTTSTPGPTPTTSVTPPPTTTEGNVWSSHYVSPLVCTFPPEDCIWTDWIDVSYPQFGPEGGDDETFETIQNKIPSWNCTKVENVSCRAEKFPDIPIEDLGQKVECDVNTGLICKNKDQTTGGVIPMPVCLNYQIKVCCAPPLSPECTTAVTTTTTGETSTTVSLSPTTSTRYTPSVSSTTSPPTPTGSAPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPGPTPTTSVTRPPTSTEGNCLIKVCCAPPLSPECTTAVTTTTTGETSTTVSLSPTTSTRYTPSVSSTTSPPTPTGSAPTTTSGTTPSSSTIGSTVSTTPVTSPPSPSPTSVSTSTPGPTPTTSVTRPPTSTEGNCLAVVPRVPLYSGINVSSLTQSDCFIRLSFFLSFFLTSFQIQPGESWWLCNCTKAICVENNTVVIVPVICEPPPKPTCSNGLAPVQVIDDDLCCWHWECDCYCTGWGDPHYMTFDGLYYSYQGNCTYVLVEEIEKRVDNFGVYIDNYHCDARDIVSCPRALIVRHETQEVRIVTVKPNTLEVEVTVNKQPVALPYKKFGLSVYESGINRVVEIPELKMNVSFNGLSFSIRMPYSLFGNNTQGQCGICNNNTADDCRLPNGNIAENCETMADYWQVVDPSKPQCSPGLVPTKAPSTTTGKPCKESSLCELLWGSVFEKCREVVKPDKYYAACVFDSCTLPDLDLECSSLQIYAAICADQNVCVDWRSHTNGVCCKYLAIYHELFSSEHFVSYSPQNETSIKQIEGCFCPNGTMLFDSGVDVCVNTCGEFYYFTWFGEKFTADCQDCVCLEGGNGIVCEPHKCPEQNKKSCSGKGFYEVTVVNSEDPCCPTVTCKCNTSLCTTEPPKCTLGFEVFSYIPSDECCPVYKCVFVDKCHNCFCTNEVNISTQLNVISCERIPCNTYCEPGYELQHVQGECCGKCVQTKCVIHTSHSSNLILNVSMLYVLPLYKIYKLSLLKDEALCNFASEMSATYLEYSVEASSMEHSCSCCKEVETSMKEVELKCPSGHSITHKYVYVESCGCQDTQCISTQNHKRRAISLTSK", "length": 2678, "header": "tr|A0A8V1A2F1-1|A0A8V0ZPQ0_CHICK Computationally mapped isoform of Mucin 2, oligomeric mucus/gel-forming OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZPQ0-1" }, "locus": { "chromosome": "5", "start_pos": 14602158, "end_pos": 14528006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058298.1", "url": "https://www.ensembl.org/id/ENSGALT00010058298.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035417.1", "url": "https://www.ensembl.org/id/ENSGALP00010035417.1" } ] } }, { "isoform_ac": "A0A8V1A2P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0/entry#A0A8V1A2P6-1", "sequence": { "sequence": 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"Thr", "residue": "Thr", "site_lbl": "Thr1528", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1703, "start_aa": "Thr", "end_pos": 1703, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1703", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1708, "start_aa": "Thr", "end_pos": 1708, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1708", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1751, "start_aa": "Thr", "end_pos": 1751, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1751", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1755, "start_aa": "Thr", "end_pos": 1755, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1755", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1757, "start_aa": "Thr", "end_pos": 1757, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1757", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPQ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPR1-1", "uniprot_ac": "A0A8V0ZPR1", "uniprot_id": "A0A8V0ZPR1_CHICK", "mass": { "chemical_mass": 13569.0, "monoisotopic_mass": 13569.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR1", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZPR1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPR1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZPR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "QKKITEPRFYLLFFFPFLGWALQQTPDMIVRLGDSLTLNCSHKESGFWTMFWYKLPVGKNATLQLIVRSVEGNKAEFEEEFKSRFQSSGTKGNSLSMAIDHVLLNDSGTYFCAKQDTL", "length": 118, "header": "tr|A0A8V0ZPR1-1|A0A8V0ZPR1_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZPR1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR1/entry#A0A8V0ZPR1-1", "sequence": { "sequence": "QKKITEPRFYLLFFFPFLGWALQQTPDMIVRLGDSLTLNCSHKESGFWTMFWYKLPVGKNATLQLIVRSVEGNKAEFEEEFKSRFQSSGTKGNSLSMAIDHVLLNDSGTYFCAKQDTL", "length": 118, "header": "tr|A0A8V0ZPR1-1|A0A8V0ZPR1_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZPR1-1" }, "locus": { "chromosome": "1", "start_pos": 78283195, "end_pos": 78282021, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058297.1", "url": "https://www.ensembl.org/id/ENSGALT00010058297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035416.1", "url": "https://www.ensembl.org/id/ENSGALP00010035416.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPR1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPR1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 118, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPS2-1", "uniprot_ac": "A0A8V0ZPS2", "uniprot_id": "A0A8V0ZPS2_CHICK", "mass": { "chemical_mass": 76538.0, "monoisotopic_mass": 76538.0 }, "refseq": {}, "gene_names": [ { "name": "HSPA12A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2" } ] } ], "protein_names": [ { "name": "Heat shock 70 kDa protein 12A", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Adapter protein for SORL1, but not SORT1. Delays SORL1 internalization and affects SORL1 subcellular localization.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2#function" }, { "database": "UniProtKB", "id": "ARBA00058224", "url": "https://www.uniprot.org/uniprotkb/ARBA00058224#function" }, { "database": "UniProtKB", "id": "A0A8V0ZRM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZSG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSG4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "HSPA12A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2", "locus": { "chromosome": "6", "start_pos": 29661782, "end_pos": 29711061, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022749", "url": "https://www.ensembl.org/id/ENSGALG00010022749" } ] } } ], "crossref": [ { "id": "A0A8V0ZPS2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPS2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11735", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11735", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423917", "url": "https://www.ncbi.nlm.nih.gov/gene/423917", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026685", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026685", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPS2", "url": "https://www.orthodb.org/?gene=A0A8V0ZPS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRM2", "url": "https://www.orthodb.org/?gene=A0A8V0ZRM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSG4", "url": "https://www.orthodb.org/?gene=A0A8V0ZSG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14187", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14187", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14187:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14187:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSG4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSG4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGIGASEGHRLRKSPLQRQMKQCDAVSTSAYSSPAKSLGDPGITPLSPSHIVKDSDAEDAVEQLFLVVVAIDFGTTSSGYAYSFTKEPECIHVMRRWEGGDPGVSNQKTPTTILLTPERKFHSFGYAARDFYHDLDPSESKHWLYFEKFKMKLHTTSNLTMETDLTAANGKKVKALEIFAYALQFFKEQALKELSDQAGSDFENTEVRWVITVPAIWKQPAKQFMRQAAYKAGMASPENPEQLIIALEPEAASIYCRKLRLHQMIELSSRAPVNGYSPSDTIGTGFTQAKEHVRRNRQSRTFLVENVIGEIWSELEEGDRYIVVDSGGGTVDMTVHQIRLPEGHLKELYKATGGPYGSLGVDYEFEKLLCKIFGEDFIEQFKIKRPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRGHSVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDQIVQHLSDVFDKPEVTNVKFLFLVGGFAESPLLQQAVQSAFGSRCRVIIPQDVGLTILKGAVLFGLDPAVIKVRRSPLTYGVGVLNRFVEGRHPPEKLLIKDGTRWCTDVFDKFISADQSVALGETVTRSYTPAKPSQLVIVINIYSSEQDNVSFITESGVKKCGTLRLDLTGTDASVPNRREIKTLMQFGDTEIKAMAIDVATSKSVKVGIDFLNY", "length": 685, "header": "tr|A0A8V0ZPS2-1|A0A8V0ZPS2_CHICK Isoform 1 of Heat shock 70 kDa protein 12A OS=Gallus gallus OX=9031 GN=HSPA12A PE=1 SV=1 CANONICAL=A0A8V0ZPS2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2/entry#A0A8V0ZPS2-1", "sequence": { "sequence": "MSGIGASEGHRLRKSPLQRQMKQCDAVSTSAYSSPAKSLGDPGITPLSPSHIVKDSDAEDAVEQLFLVVVAIDFGTTSSGYAYSFTKEPECIHVMRRWEGGDPGVSNQKTPTTILLTPERKFHSFGYAARDFYHDLDPSESKHWLYFEKFKMKLHTTSNLTMETDLTAANGKKVKALEIFAYALQFFKEQALKELSDQAGSDFENTEVRWVITVPAIWKQPAKQFMRQAAYKAGMASPENPEQLIIALEPEAASIYCRKLRLHQMIELSSRAPVNGYSPSDTIGTGFTQAKEHVRRNRQSRTFLVENVIGEIWSELEEGDRYIVVDSGGGTVDMTVHQIRLPEGHLKELYKATGGPYGSLGVDYEFEKLLCKIFGEDFIEQFKIKRPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRGHSVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDQIVQHLSDVFDKPEVTNVKFLFLVGGFAESPLLQQAVQSAFGSRCRVIIPQDVGLTILKGAVLFGLDPAVIKVRRSPLTYGVGVLNRFVEGRHPPEKLLIKDGTRWCTDVFDKFISADQSVALGETVTRSYTPAKPSQLVIVINIYSSEQDNVSFITESGVKKCGTLRLDLTGTDASVPNRREIKTLMQFGDTEIKAMAIDVATSKSVKVGIDFLNY", "length": 685, "header": "tr|A0A8V0ZPS2-1|A0A8V0ZPS2_CHICK Isoform 1 of Heat shock 70 kDa protein 12A OS=Gallus gallus OX=9031 GN=HSPA12A PE=1 SV=1 CANONICAL=A0A8V0ZPS2-1" }, "locus": { "chromosome": "6", "start_pos": 29710910, "end_pos": 29663805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055308.1", "url": "https://www.ensembl.org/id/ENSGALT00010055308.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033476.1", "url": "https://www.ensembl.org/id/ENSGALP00010033476.1" } ] } }, { "isoform_ac": "A0A8V0ZRM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2/entry#A0A8V0ZRM2-1", "sequence": { "sequence": "MSESEGGAADAVSTSAYSSPAKSLGDPGITPLSPSHIVDSDAEDAVEQLFLVVVAIDFGTTSSGYAYSFTKEPECIHVMRRWEGGDPGVSNQKTPTTILLTPERKFHSFGYAARDFYHDLDPSESKHWLYFEKFKMKLHTTSNLTMETDLTAANGKKVKALEIFAYALQFFKEQALKELSDQAGSDFENTEVRWVITVPAIWKQPAKQFMRQAAYKAGMASPENPEQLIIALEPEAASIYCRKLRLHQMIELSSRAPVNGYSPSDTIGTGFTQAKEHVRRNRQSRTFLVENVIGEIWSELEEGDRYIVVDSGGGTVDMTVHQIRLPEGHLKELYKATGGPYGSLGVDYEFEKLLCKIFGEDFIEQFKIKRPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRGHSVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDQIVQHLSDVFDKPEVTNVKFLFLVGGFAESPLLQQAVQSAFGSRCRVIIPQDVGLTILKGAVLFGLDPAVIKVRRSPLTYGVGVLNRFVEGRHPPEKLLIKDGTRWCTDVFDKFISADQSVALGETVTRSYTPAKPSQLVIVINIYSSEQDNVSFITESGVKKCGTLRLDLTGTDASVPNRREIKTLMQFGDTEIKAMAIDVATSKSVKVGIDFLNY", "length": 669, "header": "tr|A0A8V0ZRM2-1|A0A8V0ZRM2_CHICK Computationally mapped isoform of Heat shock 70 kDa protein 12A OS=Gallus gallus OX=9031 GN=HSPA12A PE=1 SV=1 CANONICAL=A0A8V0ZPS2-1" }, "locus": { "chromosome": "6", "start_pos": 29710528, "end_pos": 29663805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055310.1", "url": "https://www.ensembl.org/id/ENSGALT00010055310.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033478.1", "url": "https://www.ensembl.org/id/ENSGALP00010033478.1" } ] } }, { "isoform_ac": "A0A8V0ZSG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2/entry#A0A8V0ZSG4-1", "sequence": { "sequence": "MSESEGGAADAVSTSAYSSPAKSLGDPGITPLSPSHIVKDSDAEDAVEQLFLVVVAIDFGTTSSGYAYSFTKEPECIHVMRRWEGGDPGVSNQKTPTTILLTPERKFHSFGYAARDFYHDLDPSESKHWLYFEKFKMKLHTTSNLTMETDLTAANGKKVKALEIFAYALQFFKEQALKELSDQAGSDFENTEVRWVITVPAIWKQPAKQFMRQAAYKAGMASPENPEQLIIALEPEAASIYCRKLRLHQMIELSSRAPVNGYSPSDTIGTGFTQAKEHVRRNRQSRTFLVENVIGEIWSELEEGVDYEFEKLLCKIFGEDFIEQFKIKRPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRGHSVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDQIVQHLSDVFDKPEVTNVKFLFLVGGFAESPLLQQAVQSAFGSRCRVIIPQDVGLTILKGAVLFGLDPAVIKVRRSPLTYGVGVLNRFVEGRHPPEKLLIKDGTRWCTDVFDKFISADQSVALGETVTRSYTPAKPSQLVIVINIYSSEQDNVSFITESGVKKCGTLRLDLTGTDASVPNRREIKTLMQFGDTEIKAMAIDVATSKSVKVGIDFLNY", "length": 628, "header": "tr|A0A8V0ZSG4-1|A0A8V0ZPS2_CHICK Computationally mapped isoform of Heat shock 70 kDa protein 12A OS=Gallus gallus OX=9031 GN=HSPA12A PE=1 SV=1 CANONICAL=A0A8V0ZPS2-1" }, "locus": { "chromosome": "6", "start_pos": 29710528, "end_pos": 29663805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055304.1", "url": "https://www.ensembl.org/id/ENSGALT00010055304.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033472.1", "url": "https://www.ensembl.org/id/ENSGALP00010033472.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 620, "end_pos": 622 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPT8-1", "uniprot_ac": "A0A8V0ZPT8", "uniprot_id": "A0A8V0ZPT8_CHICK", "mass": { "chemical_mass": 116404.0, "monoisotopic_mass": 116404.0 }, "refseq": {}, "gene_names": [ { "name": "THSD4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8" } ] } ], "protein_names": [ { "name": "Thrombospondin type 1 domain containing 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "THSD4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8", "locus": { "chromosome": "10", "start_pos": 6606730, "end_pos": 6350064, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022759", "url": "https://www.ensembl.org/id/ENSGALG00010022759" } ] } } ], "crossref": [ { "id": "A0A8V0ZPT8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "415395", "url": "https://www.ncbi.nlm.nih.gov/gene/415395", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415395", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415395", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SQRRCMH", "url": "https://omabrowser.org/oma/group/SQRRCMH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPT3", "url": "https://www.orthodb.org/?gene=A0A8V0ZPT3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPT8", "url": "https://www.orthodb.org/?gene=A0A8V0ZPT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRN1", "url": "https://www.orthodb.org/?gene=A0A8V0ZRN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRN6", "url": "https://www.orthodb.org/?gene=A0A8V0ZRN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5173214", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZPT3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDSLIVSLRLLSSLAVLGFQFVIPQPSIEHRKVPQRIEEQRDASEDSGAGIPGMWGSWGPWSACSRSCSGGVMEQTRPCLPAYYRERGYQRPGRQYAASERTLAHQNSRHQDSLTAYPGHIISAIRTSVPLHRNEEQLRAGLRASAPSEGHNNSHMSRGAPRGSRHSQSQRHHPKPEKRSRNRNPIGPGKYGYGKVPYILPLQTDTGQQPQKLRRQRQSSRNNVFHQSPSLMNAYSQPASASLQHGNLYQEESGPQAGHQVLGPSVYQSPSFPASQNLFHSSDSTLHGSASHPMVQGQPQPQRSAAIVCVGTYKQYKLCNTNMCPESSRSIREVQCASYNNKPFMGRFYEWEPFAEVKGSQKCELNCRAIGYRFYVRQAEKVIDGTPCDQNGTSICVAGQCKSIGCDDYLGSDKVIDKCGICGGDNTACKVVSGVFKHTLTNLGYHKIVEIPEGATKINITEMSKSNNYLALRSRSGRSIINGNWAIDRPGRYEGGGTMFTYKRPNEISSTAGESFLADGPTNEVLDVYMIHQQPNPGIHYEYIIPGDNVISPQLLAHRRPGEPLNGQLEMPESTNHNEDDLHRETDTLTGQSVGTFPVIPPGRFPSHQPENQVPAVQLSRQNREYNWKQIGKTECTTTCGKGSQYPVFHCVNRVTHEEVPENYCDSSTKPIPEEEACNIFPCPAFWDIGEWSECSKTCGLGMQHRQILCRQIYANRTLTVQQYRCHHLEKPETTSTCQLKICSEWQIRTEWTSCSVPCGVGQRTRDVKCVSNLGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSDRCSAECGDGIRTRSVVCMTNHVSSLPLEGCGNNRPSETTPCNNGPCAGKVEWFAGSWSQCSTECGGGTQQREVICVRKTEGNFDVLNPYECSYVERPPSQQSCYLKPCGSKWFHTEWSTCSKSCEGGFRVREVRCLSDDMTTSTHCDPQLKPEEKEPCNTHDCIPEIGKVEELCVLTMELHLVEKEMRTAKINTTIAMWWFRPGFVSTPITKQPVVHPVRVWQIDNLGF", "length": 1041, "header": "tr|A0A8V0ZPT8-1|A0A8V0ZPT8_CHICK Isoform 1 of Thrombospondin type 1 domain containing 4 OS=Gallus gallus OX=9031 GN=THSD4 PE=4 SV=1 CANONICAL=A0A8V0ZPT8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8/entry#A0A8V0ZPT3-1", "sequence": { "sequence": "MFVSYLILTLLYFQTAVLARPGGESIGCDDYLGSDKVIDKCGICGGDNTACKVVSGVFKHTLTNLGYHKIVEIPEGATKINITEMSKSNNYLALRSRSGRSIINGNWAIDRPGRYEGGGTMFTYKRPNEISSTAGESFLADGPTNEVLDVYMIHQQPNPGIHYEYIIPGDNVISPQLLAHRRPGEPLNGQLEMPESTNHNEDDLHRETDTLTGQSVGTFPVIPPGRFPSHQPENQVPAVQLSRQNREYNWKQIGKTECTTTCGKGSQYPVFHCVNRVTHEEVPENYCDSSTKPIPEEEACNIFPCPAFWDIGEWSECSKTCGLGMQHRQILCRQIYANRTLTVQQYRCHHLEKPETTSTCQLKICSEWQIRTEWTSCSVPCGVGQRTRDVKCVSNLGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSDRCSAECGDGIRTRSVVCMTNHVSSLPLEGCGNNRPSETTPCNNGPCAGKVEWFAGSWSQCSTECGGGTQQREVICVRKTEGNFDVLNPYECSYVERPPSQQSCYLKPCGSKWFHTEWSTCSKSCEGGFRVREVRCLSDDMTTSTHCDPQLKPEEKEPCNTHDCIPEIDENCKDKYYNCNVVVQARLCVYTYYKTACCASCTRVANRQSGLLGHR", "length": 647, "header": "tr|A0A8V0ZPT3-1|A0A8V0ZPT8_CHICK Computationally mapped isoform of Thrombospondin type 1 domain containing 4 OS=Gallus gallus OX=9031 GN=THSD4 PE=4 SV=1 CANONICAL=A0A8V0ZPT8-1" }, "locus": { "chromosome": "10", "start_pos": 6605737, "end_pos": 6502960, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055321.1", "url": "https://www.ensembl.org/id/ENSGALT00010055321.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033486.1", "url": "https://www.ensembl.org/id/ENSGALP00010033486.1" } ] } }, { "isoform_ac": "A0A8V0ZPT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8/entry#A0A8V0ZPT8-1", "sequence": { "sequence": "MVDSLIVSLRLLSSLAVLGFQFVIPQPSIEHRKVPQRIEEQRDASEDSGAGIPGMWGSWGPWSACSRSCSGGVMEQTRPCLPAYYRERGYQRPGRQYAASERTLAHQNSRHQDSLTAYPGHIISAIRTSVPLHRNEEQLRAGLRASAPSEGHNNSHMSRGAPRGSRHSQSQRHHPKPEKRSRNRNPIGPGKYGYGKVPYILPLQTDTGQQPQKLRRQRQSSRNNVFHQSPSLMNAYSQPASASLQHGNLYQEESGPQAGHQVLGPSVYQSPSFPASQNLFHSSDSTLHGSASHPMVQGQPQPQRSAAIVCVGTYKQYKLCNTNMCPESSRSIREVQCASYNNKPFMGRFYEWEPFAEVKGSQKCELNCRAIGYRFYVRQAEKVIDGTPCDQNGTSICVAGQCKSIGCDDYLGSDKVIDKCGICGGDNTACKVVSGVFKHTLTNLGYHKIVEIPEGATKINITEMSKSNNYLALRSRSGRSIINGNWAIDRPGRYEGGGTMFTYKRPNEISSTAGESFLADGPTNEVLDVYMIHQQPNPGIHYEYIIPGDNVISPQLLAHRRPGEPLNGQLEMPESTNHNEDDLHRETDTLTGQSVGTFPVIPPGRFPSHQPENQVPAVQLSRQNREYNWKQIGKTECTTTCGKGSQYPVFHCVNRVTHEEVPENYCDSSTKPIPEEEACNIFPCPAFWDIGEWSECSKTCGLGMQHRQILCRQIYANRTLTVQQYRCHHLEKPETTSTCQLKICSEWQIRTEWTSCSVPCGVGQRTRDVKCVSNLGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSDRCSAECGDGIRTRSVVCMTNHVSSLPLEGCGNNRPSETTPCNNGPCAGKVEWFAGSWSQCSTECGGGTQQREVICVRKTEGNFDVLNPYECSYVERPPSQQSCYLKPCGSKWFHTEWSTCSKSCEGGFRVREVRCLSDDMTTSTHCDPQLKPEEKEPCNTHDCIPEIGKVEELCVLTMELHLVEKEMRTAKINTTIAMWWFRPGFVSTPITKQPVVHPVRVWQIDNLGF", "length": 1041, "header": "tr|A0A8V0ZPT8-1|A0A8V0ZPT8_CHICK Isoform 1 of Thrombospondin type 1 domain containing 4 OS=Gallus gallus OX=9031 GN=THSD4 PE=4 SV=1 CANONICAL=A0A8V0ZPT8-1" }, "locus": { "chromosome": "10", "start_pos": 6605726, "end_pos": 6369975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055328.1", "url": "https://www.ensembl.org/id/ENSGALT00010055328.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033491.1", "url": "https://www.ensembl.org/id/ENSGALP00010033491.1" } ] } }, { "isoform_ac": "A0A8V0ZRN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8/entry#A0A8V0ZRN1-1", "sequence": { "sequence": "MRHISILTPSAEVQKLLSSLAVLGFQFVIPQPSIEHRKVPQRIEEQRDASEDSGAGIPGMWGSWGPWSACSRSCSGGVMEQTRPCLPAYYRERGYQRPGRQYAASERTLAHQNSRHQDSLTAYPGHIISAIRTSVPLHRNEEQLRAGLRASAPSEGHNNSHMSRGAPRGSRHSQSQRHHPKPEKRSRNRNPIGPGKYGYGKVPYILPLQTDTGQQPQKLRRQRQSSRNNVFHQSPSLMNAYSQPASASLQHGNLYQEESGPQAGHQVLGPSVYQSPSFPASQNLFHSSDSTLHGSASHPMVQGQPQPQRSAAIVCVGTYKQYKLCNTNMCPESSRSIREVQCASYNNKPFMGRFYEWEPFAEVKGSQKCELNCRAIGYRFYVRQAEKVIDGTPCDQNGTSICVAGQCKSIGCDDYLGSDKVIDKCGICGGDNTACKVVSGVFKHTLTNLGYHKIVEIPEGATKINITEMSKSNNYLALRSRSGRSIINGNWAIDRPGRYEGGGTMFTYKRPNEISSTAGESFLADGPTNEVLDVYMIHQQPNPGIHYEYIIPGDNVISPQLLAHRRPGEPLNGQLEMPESTNHNEDDLHRETDTLTGQSVGTFPVIPPGRFPSHQPENQVPAVQLSRQNREYNWKQIGKTECTTTCGKGSQYPVFHCVNRVTHEEVPENYCDSSTKPIPEEEACNIFPCPAFWDIGEWSECSKTCGLGMQHRQILCRQIYANRTLTVQQYRCHHLEKPETTSTCQLKICSEWQIRTEWTSCSVPCGVGQRTRDVKCVSNLGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSDRCSAECGDGIRTRSVVCMTNHVSSLPLEGCGNNRPSETTPCNNGPCAGKVEWFAGSWSQCSTECGGGTQQREVICVRKTEGNFDVLNPYECSYVERPPSQQSCYLKPCGSKWFHTEWSTCSKSCEGGFRVREVRCLSDDMTTSTHCDPQLKPEEKEPCNTHDCIPEIDENCKDKYYNCNVVVQARLCVYTYYKTACCASCTRVANRQSGLLGHR", "length": 1031, "header": "tr|A0A8V0ZRN1-1|A0A8V0ZRN1_CHICK Computationally mapped isoform of Thrombospondin type 1 domain containing 4 OS=Gallus gallus OX=9031 GN=THSD4 PE=4 SV=1 CANONICAL=A0A8V0ZPT8-1" }, "locus": { "chromosome": "10", "start_pos": 6605737, "end_pos": 6372729, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055323.1", "url": "https://www.ensembl.org/id/ENSGALT00010055323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033488.1", "url": "https://www.ensembl.org/id/ENSGALP00010033488.1" } ] } }, { "isoform_ac": "A0A8V0ZRN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8/entry#A0A8V0ZRN6-1", "sequence": { "sequence": "MVDSLIVSLRLLSSLAVLGFQFVIPQPSIEHRKVPQRIEEQRDASEDSGAGIPGMWGSWGPWSACSRSCSGGVMEQTRPCLPAYYRERGYQRPGRQYAASERTLAHQNSRHQDSLTAYPGHIISAIRTSVPLHRNEEQLRAGLRASAPSEGHNNSHMSRGAPRGSRHSQSQRHHPKPEKRSRNRNPIGPGKYGYGKVPYILPLQTDTGQQPQKLRRQRQSSRNNVFHQSPSLMNAYSQPASASLQHGNLYQEESGPQAGHQVLGPSVYQSPSFPASQNLFHSSDSTLHGSASHPMVQGQPQPQRSAAIVCVGTYKQYKLCNTNMCPESSRSIREVQCASYNNKPFMGRFYEWEPFAEVKGSQKCELNCRAIGYRFYVRQAEKVIDGTPCDQNGTSICVAGQCKSIGCDDYLGSDKVIDKCGICGGDNTACKVVSGVFKHTLTNLGYHKIVEIPEGATKINITEMSKSNNYLALRSRSGRSIINGNWAIDRPGRYEGGGTMFTYKRPNEISSTAGESFLADGPTNEVLDVYMIHQQPNPGIHYEYIIPGDNVISPQLLAHRRPGEPLNGQLEMPESTNHNEDDLHRETDTLTGQSVGTFPVIPPGRFPSHQPENQVPAVQLSRQNREYNWKQIGKTECTTTCGKGSQYPVFHCVNRVTHEEVPENYCDSSTKPIPEEEACNIFPCPAFWDIGEWSECSKTCGLGMQHRQILCRQIYANRTLTVQQYRCHHLEKPETTSTCQLKICSEWQIRTEWTSCSVPCGVGQRTRDVKCVSNLGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSDRCSAECGDGIRTRSVVCMTNHVSSLPLEGCGNNRPSETTPCNNGPCAGKVEWFAGSWSQCSTECGGGTQQREVICVRKTEGNFDVLNPYECSYVERPPSQQSCYLKPCGSKWFHTEWSTCSKSCEGGFRVREVRCLSDDMTTSTHCDPQLKPEEKEPCNTHDCIPEIDENCKDKYYNCNVVVQARLCVYTYYKTACCASCTRVANRQSGLLGHR", "length": 1026, "header": "tr|A0A8V0ZRN6-1|A0A8V0ZRN6_CHICK Computationally mapped isoform of Thrombospondin type 1 domain containing 4 OS=Gallus gallus OX=9031 GN=THSD4 PE=4 SV=1 CANONICAL=A0A8V0ZPT8-1" }, "locus": { "chromosome": "10", "start_pos": 6605737, "end_pos": 6369975, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055330.1", "url": "https://www.ensembl.org/id/ENSGALT00010055330.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033493.1", "url": "https://www.ensembl.org/id/ENSGALP00010033493.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415395", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415395", "resource": "KEGG Pathway" }, { "id": "R-GGA-5173214", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5173214", "resource": "Reactome", "description": "O-glycosylation of TSR domain-containing proteins" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AN95-1", "protein_name": "Thrombospondin type-1 domain-containing protein 4", "gene_name": "Thsd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSHLTSCLSALGALLLLGSQLVCPQPSTEHRKVPQRMAVAEGTPEDSGGGSPGVWGSWGPWSACSRSCSGGVMEQTRPCLPSSYRAPAGSRPSGPTLSITGHVVSAVRTSVPLHRSHEEQRTLAGSSASRQGPTVVRGSRHPQARSREPSERRSRTRGPIGPGKYGYGKAPYILPLQTDTTHTPQRLRRQRPSSRPSRSQEASASKQGYRPPTHHFSHNRPLYQSDSGPRSGLPPSEASIYQLPLTHDQNYPAASSLFHSPELSSNNGARPHGTSQAFSQHLRSTAISCIGAYRQYKLCNTNACPDSGRSIREVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQATGYRFYVRQAERVIDGTPCDQNGTAICVSGQCKSIGCDDFLGSDKVVDKCGVCGGDNTGCQVVSGVFKHALTSLGYHRVVEIPQGATKINITEMHKSNNYLALRSRSGRSIINGNWAIDRPGKYEGGGTMFTYKRPNEISSTAGESFLAEGPTNEILDVYMIHQQPNPGVHYEYVIMGNNAISPQVPPHRRPGEPFNGQLETEDGGQEDREEREKNQEKEDSHVEAPEVFTSESTQTFPVRHPERFPSHRPDNLVPPAPQHPRRNRDHNWKQLGTTECSTTCGKGSQYPIFRCVHRNTHEEVPESYCDSSMKPTPEEEPCNLFPCPAFWDIGEWSECSKTCGLGMQHRQVLCRQVYANRSLTVQPYRCQHLEKPETTSTCQLKICSEWQTRTDWTSCSVPCGVGQRTRDVKCVSNIGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSERCSAECGAGVRTRSVVCMTNHISSLPLEGCGNNRPAEATPCDNGPCTGKVEWFTGSWSQCSVECGSGTQQREVICVRKNADTFEVLDPYECSFLEKPPSQQACHLKPCGAKWFSTEWSMCSKSCQGGFRVREVRCLSDDMTPGSLCDPQLKPEERESCNPQDCVPEVDENCKDKYYNCNVVVQARLCVYNYYKTACCASCTRVANRHTGFLGSR", "length": 1017 }, "evidence": [ { "id": "A0A8V0ZPT8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPT8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SIR7-1", "protein_name": "Thrombospondin type-1 domain-containing protein 4", "gene_name": "THSD4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVSCFMGSLSVLGSLVLLGLQLVCPQPSTEHRKVPQRMAVAEGAPEDGGGGAPGVWGAWGPWSACSRSCSGGVMEQTRPCLPGSYRVRGGPRPAAPFTGHVVSAVRTSVPLHRSREEPRGPTGLNASRQGPALRGSRHPQARGREPTAERRSRIRGPIGPGKYGYGKAPYILPLQTDSAHSPQRLRRQRPPSRNSRSQGASGSSHSYNPAAHRTPQHGPLYQSDDGPRSGLQASESSIYQLPLTHNQGFPAASSLFHSQETSSSPGMGAHRAAQSFSQPARSTAISCIGAYRQYKLCNTNVCPESSRSIWEVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQAMGYRFYVRQAEKVIDGTPCDQNGTAICVSGQCKSIGCDDYLGSDKVVDKCGVCGGDNTGCQVVSGVFKHALTSLGYHRVVEIPQGATKINITEMYKSNNYLALRSRSGRSIINGNWAIDRPGKYEGGGTMFTYKRPNEISSTAGESFLAEGPTNEILDVYMIHQQPNPGVHYEYVIMGNNAISPQVPPHRRPGEPFNGQLGPEGRSQEEGEEKEGDEPKADTHGGAPEIFTSESAQTFPVRHPDRFSSHRPDNVVPPAPQPPRRSRDHNWKQLGTTECSTTCGKGSQYPIFRCVHRSTHEEVPESYCDSSMKPTPEEEPCNIFPCPAFWDIGEWSECSKTCGLGMQHRQVLCRQVYANRSLTVQPYRCQHLEKPETTSTCQLKICSEWQIRTDWTSCSVPCGVGQRTRDVKCVSNIGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSERCSAECGAGVRTRSVVCMTNHVSSLPLEGCGNNRPAEATPCDNGPCTGKVEWFAGSWSQCSVECGSGTQQREVICVRKNADTFEVLDPYECSFLERPPSQQSCHLKPCGAKWFNTEWSMCSKSCQGGFRVREVRCLSDDMTLSNLCDPQLKPEEKESCNPQDCVPEVDENCKDRYYNCNVVVQARLCVYNYYKTACCVSCTRVASRHSGFLGSR", "length": 1014 }, "evidence": [ { "id": "A0A8V0ZPT8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPT8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3UTY6-1", "protein_name": "Thrombospondin type-1 domain-containing protein 4", "gene_name": "Thsd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSYLTSCLSALSTLLLLLGSQLVCPQPSTEHRKVPQRMAVTEGTPEDSGSGSPGVWGSWGPWSACSRSCSGGVMEQTRPCLPSSYRARGGSRPNGRALSITGHVVSAVRTSVPLHRSQEDQRALAGSNASRQGPAVVRGSRHPQARGREPSERRSRTRGPIGPGKYGYGKAPYILPLQTDTTHTPQRLRRQRPSSRHSRSQEASASKQGYRPPTHQFSHSQPLYQSDSGPRSGLPPSEASIYQLPLTHDQSYPAASSLFHRPELSSHHGARPHGAAQAFPQHLRSTAISCIGAYRQYKLCNTNACPESGRSIREVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQATGYRFYVRQAEKVIDGTPCDQNGTAICVSGQCKSIGCDDFLGSDKVLDKCGVCGGDNTGCQVVSGVFKHALTSLGYHRVVEIPQGATKINITEMHKSNNYLALRSRSGRSIINGNWAIDRPGKYEGGGTMFTYKRPNEVSSTAGESFLAEGPTNEILDVYMIHQQPNPGVHYEYVIMRNNAISPQVPPHRRPGEPFNGQLEEEDRGQEDREEREKNQEKEDSQVEAPEVFTSESTQTFPVRHPERFPSHRPDNLVPPAPQPPRRSRDHNWKQLGTTECSTTCGKGSQYPIFRCVHRNTHEEVPESYCDSSMKPTPEEEPCNLFPCPAFWDIGEWSECSKTCGLGMQHRQVLCRQVYANRSLTVQPYRCQHLEKPETTSTCQLKICSEWQIRTDWTSCSVPCGVGQRTRDVKCVSNIGDMVHDEECNMKLRPNDIENCDMGPCAKSWFLTEWSERCSAECGAGVRTRSVVCMTNHVSSLPLEGCGNNRPVEATPCDNGPCTGKVEWFTGSWSQCSIECGSGTQQREVICVRKNADTFEVLDPYECSFLEKPPSQQACHLKPCGAKWFSTEWSMCSKSCQGGFRVREVRCLSDDMTPSSLCDPQLKPEERESCNTQDCVPEVDENCKDKYYNCNVVVQARLCVYNYYKTACCASCTRVANRHVGFLGSR", "length": 1018 }, "evidence": [ { "id": "A0A8V0ZPT8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPT8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMP0-1", "protein_name": "Thrombospondin type-1 domain-containing protein 4", "gene_name": "THSD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSHFMGSLSVLCFLLLLGFQFVCPQPSTQHRKVPQRMAAEGAPEDDGGGGAPGVWGAWGPWSACSRSCSGGVMEQTRPCLPRSYRLRGGQRPGAPARAFADHVVSAVRTSVPLHRSRDETPALAGTDASRQGPTVLRGSRHPQPQGLEVTGDRRSRTRGTIGPGKYGYGKAPYILPLQTDTAHTPQRLRRQKLSSRHSRSQGASSARHGYSSPAHQVPQHGPLYQSDSGPRSGLQAAEAPIYQLPLTHDQGYPAASSLFHSPETSNNHGVGTHGATQSFSQPARSTAISCIGAYRQYKLCNTNVCPESSRSIREVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQAMGYRFYVRQAEKVIDGTPCDQNGTAICVSGQCKSIGCDDYLGSDKVVDKCGVCGGDNTGCQVVSGVFKHALTSLGYHRVVEIPEGATKINITEMYKSNNYLALRSRSGRSIINGNWAIDRPGKYEGGGTMFTYKRPNEISSTAGESFLAEGPTNEILDVYMIHQQPNPGVHYEYVIMGTNAISPQVPPHRRPGEPFNGQMVTEGRSQEEGEQKGRNEEKEDLRGEAPEMFTSESAQTFPVRHPDRFSPHRPDNLVPPAPQPPRRSRDHNWKQLGTTECSTTCGKGSQYPIFRCVHRSTHEEAPESYCDSSMKPTPEEEPCNIFPCPAFWDIGEWSECSKTCGLGMQHRQVLCRQVYANRSLTVQPYRCQHLEKPETTSTCQLKICSEWQIRTDWTSCSVPCGVGQRTRDVKCVSNIGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSERCSAECGAGVRTRSVVCMTNHVSSLPLEGCGNNRPAEATPCDNGPCTGKVEWFAGSWSQCSIECGSGTQQREVICVRKNADTFEVLDPSECSFLEKPPSQQSCHLKPCGAKWFSTEWSMCSKSCQGGFRVREVRCLSDDMTLSNLCDPQLKPEERESCNPQDCVPEVDENCKDKYYNCNVVVQARLCVYNYYKTACCASCTRVANRQTGFLGSR", "length": 1018 }, "evidence": [ { "id": "A0A8V0ZPT8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPT8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VKV3-1", "protein_name": "Lonely heart, isoform A", "gene_name": "loh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAKLLLIFSILTILATIHDSSFVQADLTTKERIKKHQDWLREHRKPKTKKKISINSYYELANLWHTRKDLSSPKQKPNNKEEYLENETTSKISNKSDEKVLKSSTIISLNATNPSTSTFKSVLETTTLPSVTTKDLFESGNVATTRQTPKVEEVFSSPNPPQEATSSTSKKAKKKVYPYPRWDKWSDWSSCSRSCGGGVKYQVRKCINRNLLTNNQLTSNACVGYFKRYQLCNDVPCDEQSPDFRASQCSAYNDKEFHGHRYRWEPYVKDDAECELNCMPFGMKSFATLNESVIDGTPCGHPAEYFRSQFWERAVCVDGACKAVQASGEIDGLYAHSGSVSCGGLLCRPVTGIFTRNPLPEHAYIHVTTLPVGASNISITELKNSINLLVLRTSNELAIFNGENTVSESGSYEAVGAVFDYHRIDGAEDSNGVTEWITSIGPIRDSLQLMVFTKSANNTGVKYEYMLPIVSESEENEMSLESSDGLLRSGMEDTSSSSSSRAGRKRIFNWKVIGFSSCTKSCGGGTQTPIIRCIRKNPLRYYSQRRCTHSVKPVLNENLLHCNTQPCPAYWRFDDWGECRCSSSGGLRRREVSCVQELASGLVIHVDKAACMEDQPPMQKQCECPKNRRRNLSRYRLSGPSESSSNSSQVKRSKIDGSDATAIWLVSDWNQYCSVTCGSGVEYRTVFCDRSKAGEQRCDPSTTPESRRPCEKPACELGDWFTGPWSSCNGDCFDLTRTREVLCIRSQLITEHSECTPELKPQSVEKCSHEEVEYCAARWHYSDWSECTKPCGGGTQRRSVRCLEYDIKMNALRESTHCRYTNREPIYRNCNVQACAEVPKTEVTPVCADKFSNCQWASQAKLCSYDYYRDNCCFSCTGGI", "length": 880 }, "evidence": [ { "id": "A0A8V0ZPT8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPT8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microfibril", "id": "GO:0001527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001527", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microfibril assembly", "id": "GO:0160054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160054", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPT8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1005, "end_pos": 1007, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 717, "end_pos": 719, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8" }, { "id": "PF05986", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ADAMTS/ADAMTS-like Spacer 1", "eco_id": "ECO_0000259", "start_pos": 433, "end_pos": 547, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZPT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPT8" }, { "id": "PF19236", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ADAMTS/ADAMTS-like cysteine-rich", "eco_id": "ECO_0000259", "start_pos": 343, "end_pos": 430, "start_aa": "Lys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1005, "end_pos": 1007 }, { "start_pos": 153, "end_pos": 155 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 717, "end_pos": 719 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A8V0ZPU8_CHICK", "mass": { "chemical_mass": 30843.0, "monoisotopic_mass": 30843.0 }, "refseq": { "ac": "NP_990737", "name": "Y-box-binding protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990737" }, "gene_names": [ { "name": "YBX3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU8" } ] }, { "name": "CSDA", "type": "synonym", "evidence": [ { "id": "NP_990737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990737" } ] }, { "name": "YBX3", "type": "synonym", "evidence": [ { "id": "NP_990737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990737" } ] } ], "protein_names": [ { "name": "Rous sarcoma virus transcription enhancer factor II", "type": "synonym", "evidence": [ { "id": "NP_990737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990737" } ] }, { "name": "Y-box binding protein 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU8/entry#names_and_taxonomy" } ] }, { "name": "Y-box-binding protein 3", "type": "synonym", "evidence": [ { "id": "NP_990737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990737" } ] }, { "name": "cold shock domain protein A", "type": "synonym", "evidence": [ { "id": "NP_990737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990737" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01005048.1, SRR13267662.16926.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000017.1. On Feb 21, 2015 this sequence version replaced NP_990737.1.", "evidence": [ { "database": "RefSeq", "id": "NP_990737", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990737" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "YBX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU8", "locus": { "chromosome": "1", "start_pos": 78415337, "end_pos": 78386950, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023957", "url": "https://www.ensembl.org/id/ENSGALG00010023957" } ] } } ], "crossref": [ { "id": "A0A8V0ZPU8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPU8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04458", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04458", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396371", "url": "https://www.ncbi.nlm.nih.gov/gene/396371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396371", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FYPQFRQ", "url": "https://omabrowser.org/oma/group/FYPQFRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPU8", "url": "https://www.orthodb.org/?gene=A0A8V0ZPU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11544", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11544", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_990737", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_990737", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEAAETGTASGTAPAAAAPAPPPPPPAAAPPDVKPKSPVSGAAPGASGGEVAPAASGSAAATTAAAAAGETEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYFGRRRGPPRSGVEGEIKDGVTEGGQIHQQVQRNPTYRPRYRRGPLRPRPAPVAGEAENKENQHEAGAVSQQPLRRGYRRPYNYRRRPRPPNTPAQDGKETKVTETPAENPAPVTEQSGAE", "length": 291, "header": "tr|A0A8V0ZPU8-1|A0A8V0ZPU8_CHICK Isoform 1 of Y-box binding protein 3 OS=Gallus gallus OX=9031 GN=YBX3 PE=1 SV=1 CANONICAL=A0A8V0ZPU8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU8/entry#A0A8V0ZPU8-1", "sequence": { "sequence": "MSEAAETGTASGTAPAAAAPAPPPPPPAAAPPDVKPKSPVSGAAPGASGGEVAPAASGSAAATTAAAAAGETEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYFGRRRGPPRSGVEGEIKDGVTEGGQIHQQVQRNPTYRPRYRRGPLRPRPAPVAGEAENKENQHEAGAVSQQPLRRGYRRPYNYRRRPRPPNTPAQDGKETKVTETPAENPAPVTEQSGAE", "length": 291, "header": "tr|A0A8V0ZPU8-1|A0A8V0ZPU8_CHICK Isoform 1 of Y-box binding protein 3 OS=Gallus gallus OX=9031 GN=YBX3 PE=1 SV=1 CANONICAL=A0A8V0ZPU8-1" }, "locus": { "chromosome": "1", "start_pos": 78410291, "end_pos": 78387018, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058343.1", "url": "https://www.ensembl.org/id/ENSGALT00010058343.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035452.1", "url": "https://www.ensembl.org/id/ENSGALP00010035452.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:396371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396371", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SQ46-1", "protein_name": "Y-box binding protein 3", "gene_name": "YBX3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEAGEATTTSTTSTTTTTTTLPQAPAEAAAAAPQDPAPKSPAGSGAPQAAAPAPAALVAGNPGGDAAPAAPTAPGTAAPASSAAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNAGEIGEMKDGVPEGTQLQGPVHRNPTYRPRYRSRGPPRPRPAPAVGEAEDKENQQAANGPNQPPARRGYRRPYNYRRRPRPPNAPSQDGKETKAGEAPSDNPAPATEQSSAE", "length": 312 }, "evidence": [ { "id": "A0A8V0ZPU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPU8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6PS38-1", "protein_name": "Y-box binding protein 3", "gene_name": "YBX3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSEAGEATSTTSTAAAAPSSSAPITTAAALPQAPAEAAPQDPAPKSPAGGGAPPAPAPAALVSGNPGGDAAPGTAAPASSAAVGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRYVCVSLHTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGLEAPAAAGQFSAARSQPRRPQFRPQYRRRFPPYHVGQTFDRRSRVFPHPSRMQAGEIGEMKDGVPEGAQLQGPVHRNPTYRARYRRGPPRPRPAPAVGEAEDKENQQAANGPNQPPARRGYQRPYNYRRRPRPPNAPSQDGKETKAGEAPSENPAPAPEQSSAE", "length": 372 }, "evidence": [ { "id": "A0A8V0ZPU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPU8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P16989-1", "protein_name": "Y-box-binding protein 3", "gene_name": "YBX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEAGEATTTTTTTLPQAPTEAAAAAPQDPAPKSPVGSGAPQAAAPAPAAHVAGNPGGDAAPAATGTAAAASLATAAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFDPPATDRQFSGARNQLRRPQYRPQYRQRRFPPYHVGQTFDRRSRVLPHPNRIQAGEIGEMKDGVPEGAQLQGPVHRNPTYRPRYRSRGPPRPRPAPAVGEAEDKENQQATSGPNQPSVRRGYRRPYNYRRRPRPPNAPSQDGKEAKAGEAPTENPAPPTQQSSAE", "length": 372 }, "evidence": [ { "id": "A0A8V0ZPU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPU8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62764-1", "protein_name": "Y-box-binding protein 3", "gene_name": "Ybx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEAGEATTGGTTLPQAAADAPAAAPPDPAPKSPAASGAPQAPAPAALLAGSPGGDAAPGPAPASSAPAGSEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFEPPAADGQFSGARNQLRRPQYRPPYRQRRFPPYHVGQTFDRRSRVFPHPNRMQAGEIGEMKDGVPEGAQLQVHRNPTYRPRFRRGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRPRPLNAVSQDGKETKAGEAPTENPAPATEQSSAE", "length": 361 }, "evidence": [ { "id": "A0A8V0ZPU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPU8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JKB3-1", "protein_name": "Y-box-binding protein 3", "gene_name": "Ybx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEAGEATTGGTTLPQAAADAPAAAPPDPAPKSPAASGAPQAPAPAALLAGSPGGDAAPGPAPASSAPAGGEDAEKKVLATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPDGVPVEGSRYAADRRRYRRGYYGRRRGPPRNYAGEEEEEGSGSSEGFEPPAADGQFSGARNQLRRPQYRPPYRQRRFPPYHVGQTFDRRSRVFPHPNRMQAGEIGEMKDGVPEGTQLQAHRNPTYRPRFRRGPARPRPAPAIGEAEDKENQQAANGPNQPSARRGFRRPYNYRRRSRPLNAVSQDGKETKAGEAPTENPAPATEQSSAE", "length": 361 }, "evidence": [ { "id": "A0A8V0ZPU8", "url": "https://omabrowser.org/oma/group/A0A8V0ZPU8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": 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"name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU8" } ], "pmid": "" }, { "name": "cellular hyperosmotic response", "id": "GO:0071474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071474", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU8" } ], "pmid": "" }, { "name": "negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "id": "GO:1902219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902219", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPU8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZV20", "url": "https://www.orthodb.org/?gene=A0A8V0ZV20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1299344", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1299344", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576886", "database": "Reactome", "categories": [ 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPZ6-1", "uniprot_ac": "A0A8V0ZPZ6", "uniprot_id": "A0A8V0ZPZ6_CHICK", "mass": { "chemical_mass": 24348.0, "monoisotopic_mass": 24348.0 }, "refseq": {}, "gene_names": [ { "name": "GSC2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6" } ] } ], "protein_names": [ { "name": "Homeobox protein goosecoid-2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6/entry#names_and_taxonomy" } ] }, { "name": "Homeobox protein goosecoid-like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May have a role in development. May regulate its own transcription. May bind the bicoid consensus sequence TAATCC.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6#function" }, { "database": "UniProtKB", "id": "ARBA00058160", "url": "https://www.uniprot.org/uniprotkb/ARBA00058160#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GSC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6", "locus": { "chromosome": "15", "start_pos": 7870688, "end_pos": 7868133, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023998", "url": "https://www.ensembl.org/id/ENSGALG00010023998" } ] } } ], "crossref": [ { "id": "A0A8V0ZPZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPZ6", "url": "https://www.orthodb.org/?gene=A0A8V0ZPZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46643", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46643", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46643:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46643:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZPZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAEPTLDASSGRRAVQCSFSIENILASPAERSPQVLVPLCLQGILDCAPKGLCELEGIALQEEEEEEEEELEGAACSCCCCSHTGTRPLQDPPGWLDTRFPWPMRLLHSAVRGCKSPQGSPRELQAFQQIQRRTRRHRTIFTEEQLQALETLFHQNQYPDVITREHLANRIHLKEERVEVWFKNRRAKWRHQKRASASALVLQGSAEPPKESR", "length": 214, "header": "tr|A0A8V0ZPZ6-1|A0A8V0ZPZ6_CHICK Isoform 1 of Homeobox protein goosecoid-2 OS=Gallus gallus OX=9031 GN=GSC2 PE=3 SV=1 CANONICAL=A0A8V0ZPZ6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6/entry#A0A8V0ZPZ6-1", "sequence": { "sequence": "MSAEPTLDASSGRRAVQCSFSIENILASPAERSPQVLVPLCLQGILDCAPKGLCELEGIALQEEEEEEEEELEGAACSCCCCSHTGTRPLQDPPGWLDTRFPWPMRLLHSAVRGCKSPQGSPRELQAFQQIQRRTRRHRTIFTEEQLQALETLFHQNQYPDVITREHLANRIHLKEERVEVWFKNRRAKWRHQKRASASALVLQGSAEPPKESR", "length": 214, "header": "tr|A0A8V0ZPZ6-1|A0A8V0ZPZ6_CHICK Isoform 1 of Homeobox protein goosecoid-2 OS=Gallus gallus OX=9031 GN=GSC2 PE=3 SV=1 CANONICAL=A0A8V0ZPZ6-1" }, "locus": { "chromosome": "15", "start_pos": 7870146, "end_pos": 7868332, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058426.1", "url": "https://www.ensembl.org/id/ENSGALT00010058426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035502.1", "url": "https://www.ensembl.org/id/ENSGALP00010035502.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ6" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 193, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZPZ7-1", "uniprot_ac": "A0A8V0ZPZ7", "uniprot_id": "A0A8V0ZPZ7_CHICK", "mass": { "chemical_mass": 100012.0, "monoisotopic_mass": 100012.0 }, "refseq": { "ac": "XP_025006295", "name": "carnosine synthase 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006295" }, "gene_names": [ { "name": "CARNS1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZPZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7" } ] }, { "name": "ATPGD1", "type": "synonym", "evidence": [ { "id": "XP_025006295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006295" } ] }, { "name": "CARNS1", "type": "synonym", "evidence": [ { "id": "XP_025006295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006295" } ] } ], "protein_names": [ { "name": "Carnosine synthase 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZPZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7/entry#names_and_taxonomy" } ] }, { "name": "carnosine synthase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025006295", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006295" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025006295.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025006295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006295" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CARNS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7", "locus": { "chromosome": "5", "start_pos": 170679, "end_pos": 164879, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022409", "url": "https://www.ensembl.org/id/ENSGALG00010022409" } ] } } ], "crossref": [ { "id": "A0A8V0ZPZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZPZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100359387", "url": "https://www.ncbi.nlm.nih.gov/gene/100359387", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PISCFPG", "url": "https://omabrowser.org/oma/group/PISCFPG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZPZ7", "url": "https://www.orthodb.org/?gene=A0A8V0ZPZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48066", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48066", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48066:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48066:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-70921", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70921", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025006295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006295", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZPZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISVDRLREEQALGMKEQEWAGPEALCPGWQEEEVSDGEGPEDSGHPDPTAHAYEVLQHTLRLEGMPLTIDRTGQPRTGSGPLDMTVCVLGSPTAFLPVLLEGGTRYPGAMVLCLAPAWASRVPSETSPGSWSLLLSRGVSFEAGGCTALEEFVPPRRATYVTGTFGSEGSWEGELARDLNCPTGGSALLTRWLEDPLLSRWLLSARAGLTVPPTLAFITGLWETLPEEPEPPGVHLVRLQDPQGQESLVRDEVGAFLEGSSMQPYDQVAVRLSGWRWRGTDPHSTHRKVEGEAVAQAVAALLKGLREEESILLEALVPTARLPTLPPRSAAPRLPMALRICTVVCRSWGDRPQLCQVACTAGRAEVPVRHGSALPLGLDSSLRQWGLADAAQRQALAGQLREAAEAAMAALLAAEGELSPAQRGGARAHTDVLGVDFLLACVDGTLELVALSANCLRCLETCLLAEGMGHDVGQPAGDVPRLLAECLLHRAQCHLVEGKDILLIGAGGVSKSFVWEAAREYGLRIHLVESDPEHFAAGLVETFLPYDSREHCRDEEHAERVLEMLHARGLRPDACLSYWDDCVVLTALLCQRLGLPGCPPAAVRLAKQKSRTHQHLQRCRRGRPPPAAFSVPCRRLRSHGDVERAAGAVPFPAVAKLEFGAGAVGVRLVENAGQCHAHAAQLWHDLRADADHPGIGLGWGNAMLLMEYVPGTEHDVDLVLFEGRLLGAWVSDNGPTRVPTFLETAATLPSCLPADRQAQLVRAALRCCRACGLRHGVFNVELKLGPAGPRLLEINPRMGGFYLRDWIRAVYGPDLLLAAVLLALGLPPVLPSRPAPRQQLAGVMCLASEHGRALRGGVMAALQGLQRRGLVRLNPLFEEAGGRYEEPCLSVACAGDGPAEACGRLLGLCQALGIDSPQYPVGHFLSHFK", "length": 930, "header": "tr|A0A8V0ZPZ7-1|A0A8V0ZPZ7_CHICK Isoform 1 of Carnosine synthase 1 OS=Gallus gallus OX=9031 GN=CARNS1 PE=4 SV=1 CANONICAL=A0A8V0ZPZ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZPZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7/entry#A0A8V0ZPZ7-1", "sequence": { "sequence": "MISVDRLREEQALGMKEQEWAGPEALCPGWQEEEVSDGEGPEDSGHPDPTAHAYEVLQHTLRLEGMPLTIDRTGQPRTGSGPLDMTVCVLGSPTAFLPVLLEGGTRYPGAMVLCLAPAWASRVPSETSPGSWSLLLSRGVSFEAGGCTALEEFVPPRRATYVTGTFGSEGSWEGELARDLNCPTGGSALLTRWLEDPLLSRWLLSARAGLTVPPTLAFITGLWETLPEEPEPPGVHLVRLQDPQGQESLVRDEVGAFLEGSSMQPYDQVAVRLSGWRWRGTDPHSTHRKVEGEAVAQAVAALLKGLREEESILLEALVPTARLPTLPPRSAAPRLPMALRICTVVCRSWGDRPQLCQVACTAGRAEVPVRHGSALPLGLDSSLRQWGLADAAQRQALAGQLREAAEAAMAALLAAEGELSPAQRGGARAHTDVLGVDFLLACVDGTLELVALSANCLRCLETCLLAEGMGHDVGQPAGDVPRLLAECLLHRAQCHLVEGKDILLIGAGGVSKSFVWEAAREYGLRIHLVESDPEHFAAGLVETFLPYDSREHCRDEEHAERVLEMLHARGLRPDACLSYWDDCVVLTALLCQRLGLPGCPPAAVRLAKQKSRTHQHLQRCRRGRPPPAAFSVPCRRLRSHGDVERAAGAVPFPAVAKLEFGAGAVGVRLVENAGQCHAHAAQLWHDLRADADHPGIGLGWGNAMLLMEYVPGTEHDVDLVLFEGRLLGAWVSDNGPTRVPTFLETAATLPSCLPADRQAQLVRAALRCCRACGLRHGVFNVELKLGPAGPRLLEINPRMGGFYLRDWIRAVYGPDLLLAAVLLALGLPPVLPSRPAPRQQLAGVMCLASEHGRALRGGVMAALQGLQRRGLVRLNPLFEEAGGRYEEPCLSVACAGDGPAEACGRLLGLCQALGIDSPQYPVGHFLSHFK", "length": 930, "header": "tr|A0A8V0ZPZ7-1|A0A8V0ZPZ7_CHICK Isoform 1 of Carnosine synthase 1 OS=Gallus gallus OX=9031 GN=CARNS1 PE=4 SV=1 CANONICAL=A0A8V0ZPZ7-1" }, "locus": { "chromosome": "5", "start_pos": 170667, "end_pos": 165416, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054471.1", "url": "https://www.ensembl.org/id/ENSGALT00010054471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032906.1", "url": "https://www.ensembl.org/id/ENSGALP00010032906.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-70921", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70921", "resource": "Reactome", "description": "Histidine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L9C0-1", "protein_name": "Carnosine synthase 1", "gene_name": "Carns1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLCLDPLGTEWDHPLGSKDLDGEEEPWKGGAGLPPTDCFPGPWRQDVSLDCKGSPEEAEARAWTVYYYGLLQSCLQQAGLPETQDRSQAPRTGCPGAEVTLCILGSPSTFLSLLLEGGVQSPGNMLLCLSPAWLMKVASAGQEGEADLLVSKAVSFYPGGLTFLDDFVPPRHATYFLAGLGPEFGHSKEAAELARHLTCPTGGSSELARLLEDRLLMRWLLSQQSGVAVPATLAFTYRPPGLLRGGDTSPGLRLVELSGKEGQETLVKEEVEAFVHSKALGDASQVAVRLSGWRWRGQQVLPLHLQEEPSTVVNTVLGLLEKLEEEESVLVEAMCPPVRLPLPGSPAPGPELAVRICAVVCRIQGDRPLLSKVVCGVGRGDQPVRHHYTLPRSLGVALAQCGLEEEAQVALLEQGIKEAAEAALAAVLALEAGLSVEQRGGRQVHTDFLGVDFVLTVVGRTLTPVVLKLNSGLCLETCGALEGLWAMPRLRRSAEEAAAAPLVETMLRRSGRHLMDGKQLLVIGAGGVSKKFVWEAAQDYGLKLHLVESDPNHFASQLVQTFIHFDVTEHRRDEENARLLAELVRARNLKLDGCFSFWDDCLVLTALLCRELGLPCSPPAAMCLAKQKSRTQLHLLRCQGPPWPSTSLHAVACCPLESEADVERAIYQVPLPGVMKLEFGSGAVGVQLVKDGPQCHEHFSRILHDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVVFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKMTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLASAMVACGLQPALPAHPRARGYLVGIMCLVSQHLQLLSSPGSRETLQALHDQGQLRLNLLEEALIPGQYEEPYCNVACAGASPAEARHRLLGICQGLGIDRPNYPVAHFLSHFK", "length": 951 }, "evidence": [ { "id": "A0A8V0ZPZ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZPZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A5YM72-1", "protein_name": "Carnosine synthase 1", "gene_name": "CARNS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLCLSPAWLMKVPAPGQPGEAALLVSKAVSFHPGGLTFLDDFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELARLLEDRLLTRQLLAQQGGVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVKEEVEAFLRSEALGDILQVAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEESVLVEAVYPPAQLPCSDGPSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHNSLPRTLEVALAQCGLGEEAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDFLGVDFALTAAGGVLTPVALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLRRSARCLMEGKQLLVVGAGGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMTEHRRDEENARLLAELVRARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQKSLTQLHLLHHHGPPWPAPSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRLVEDAPQCHEHFSRITRDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVSQHLQALSSTASRETLQALHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLLGLCQGLGIDGPSYPVAHFLSHFK", "length": 827 }, "evidence": [ { "id": "A0A8V0ZPZ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZPZ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1MY45-1", "protein_name": "Carnosine synthase 1", "gene_name": "CARNS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSLDPLGPEWDCPLGSKDLEEEEGPWGGGSGLPPPGCFPGSWRHDVGLDCKGASEGADAQAWTVHYYSLLQSCLQQAGLPETQDRSQAPRTGCPGAEVTLCILGSPSTFLSVLLEAGVQSPGNMLLCLSPAWLTKVPAPGQPGEAALLVSKAVSFHPGGLTFLDDFVPPRRATYFLAGLGLGPGWGREAAELARDLTCPTGASAELARLLEDRLLTRRLLAQQGNVAVPATLAFTYKPPAPLRGGDASPGLRLVELNGKEGQETLVKEEVGAFLHSEALGDALQVAVKLSGWRWRGRQALRLYPRAEQGPVVDTVLALLEKLEEEESVLVEAVCPPARLPFAGSPPPGPELALRICAVVCRTQGDRPLLSKVVCSVGRGDRPLRHQSSLPRTLEAALAQCGLAEASQVAIVRQRVKAAAEAALAAVLTLEAGLSAEQRGGRQVRTDFLGVDFALTVAGRALTPVALELNGGLCLEACGALEGLWAAQRPGLAAEEAAAAPLVETMLRRSARCLMEGKQLLLLGAGGVSKKFVWEAARDYGLKLHLVESDPNHFASQLVQTFIHFDVTEHRRDEENARVLAELVRARGLQLDGCFSYWDDCLVLTALLCQELGLPCNPPAAMRLAKQKSRTQLHLLCRRGPPWPAPSLYAVPCCPLESEADVDRAVCQVPLPGVMKLEFGAGAVGVRLVKNASQCREHFSRIARDLQAEADHPGIGLGWGNAMLLMEFIEGTEHDVDLVLFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQLVQAAFRCCLGCGLLDGVFNVELKLTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLAAAMVACGLRPALPAHPRARGHLVGVMCLVSQHLQALSSTASPETLQALHDQGLLRLNLLEEALVPGEYEEPYCSVACAGSSPAEARHRLLGLCQGLGIDGPHYPVAYFLSHFK", "length": 951 }, "evidence": [ { "id": "A0A8V0ZPZ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZPZ7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6ZPS2-1", "protein_name": "Carnosine synthase 1", "gene_name": "Carns1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLCLSPAWLMKVATPGQEGEAVLLVSKAVSFYPGGLTFLDDFVPPRHATYFLAGLGPESGRGKEAAELARNLTCPTGTSSELSQLLENRLLMRWLLSQQSGVAVPATLAFTYRPPGLLRGGDASPGLRLVELSGKEGQETLVKEEVEAFVHSEALGDASQVAVRLSGCRWRGQQALPLHLRVEPSTVVNTVLGLLEKLEEEESVLVEAMCPPVRLPLPGGPAPGPELAVRICAVVCRIQGDRPLLSKVVCGVGRGDRPVRHHYTLPRTLRVALAQCGLEEEAQVALLEQGIKEAAEGALAAVLALEAGLSVEQRGGRQVHTDFLGVDLVLTVIGRTLTPVVLKLNSGLCLEACGALEGLWAVPRLRRSAEEAAAAPLVETMLRRSGRHLMDGKQLLVIGAGGVSKKFVWEAARDYGLTLHLVESDPNHFASQLVQTFIHFDVTEHRRDEENALLLAELVRARNLKLDGCFSFWDDCLVLTALLCRELGLPCSPPAAMCLAKQKSRTQLHLLRCQGPPWPSTSLHAVACCPLENEADVERAIYQVPLPGVMKLEFGSGAVGVQLVKDGPQCREHFSRILHDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVVFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQVVQAAFRCCLGCGLLDGVFNVELKMTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLASTMVACGLQPALPAHPRARGYLVGIMCLVSQHLQLLSSPSSRETLQTLHDQGQLRLNLLEEALIPGQYEEPYCNVACAGPSPAEACHRLLGICQGLGIDRPNYPVAHFLSHFK", "length": 827 }, "evidence": [ { "id": "A0A8V0ZPZ7", "url": "https://omabrowser.org/oma/group/A0A8V0ZPZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7" } ], "pmid": "" }, { "name": "carnosine synthase activity", "id": "GO:0047730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7" } ], "pmid": "" }, { "name": "homocarnosine synthase activity", "id": "GO:0102102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carnosine biosynthetic process", "id": "GO:0035499", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035499", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZPZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZPZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPZ7" }, { "id": "PS50975", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50975" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ATP-grasp", "eco_id": "ECO_0000259", "start_pos": 624, "end_pos": 825, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQ22-1", "uniprot_ac": "A0A8V0ZQ22", "uniprot_id": "A0A8V0ZQ22_CHICK", "mass": { "chemical_mass": 71428.0, "monoisotopic_mass": 71428.0 }, "refseq": {}, "gene_names": [ { "name": "EIF4B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ22" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 4B", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ22/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZYY0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYY0#function" }, { "database": "UniProtKB", "id": "ARBA00057062", "url": "https://www.uniprot.org/uniprotkb/ARBA00057062#function" }, { "database": "UniProtKB", "id": "A0A8V0ZQ22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ22#function" }, { "database": "UniProtKB", "id": "A0A8V0ZQ29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ29#function" }, { "database": "UniProtKB", "id": "A0A8V0ZVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVA3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ22" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EIF4B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ22", "locus": { "chromosome": "34", "start_pos": 1881699, "end_pos": 1893996, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024004", "url": "https://www.ensembl.org/id/ENSGALG00010024004" } ] } } ], "crossref": [ { "id": "A0A8V0ZQ22", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQ22", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12402", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12402", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858349", "url": "https://www.ncbi.nlm.nih.gov/gene/100858349", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ22", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ29", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVA3", "url": "https://www.orthodb.org/?gene=A0A8V0ZVA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZYY0", "url": "https://www.orthodb.org/?gene=A0A8V0ZYY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZYY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGTPRAPLDPHPSSPHPVATSGRGVVGCRQSPGADLATPPPPRPAAAKKKNKKGKTLTLTDFLAEDGGSGAPTYIPKPVSWADETDDLDGDGRVSTAWHSNDDDVYRAPLIDRSLLPTAPRAAREPNIDRSRLPKCPPYTAFLGNLPYDVTEDSIKDFFRGLNISAVRLPREPTNPERLKGFGYAEFEDIDSLFQALSLNEESLGNRRIRVDVADQAQDKDRDDRCFGRDRDRFRDSERFESDWRARPAASDSFDDFPPRRGDDAFGDRYRDRYDDRYRDGPRRDMDRGFGGRDRYDDRSRDYDRGYNSRIGSGRRAFGSGYRRDDDFRGGSDRYEERYERRDDRMERWGGRDDYGRDDFRREERGPTQRPKLNLKPRSAPKEEESTAAPAPQSSRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLEDDKRLERRPRERYPSSRSEDNPERSRTGSESSQSGAAGPPGTTAGTGPTGRTTRRRESEKSVEGDACGREEEGREEKQPLKVMPAPPPKENAWAKRSSSTAGRSPGSDSEQHSPSSSQMASRPPAENGAAPRSTHRRGDENKPDGGRDGPKARSGSSAERKDSRKEHEARAAPEPKRLEDSPAPFSHASKYAALSVDGEEEECGE", "length": 638, "header": "tr|A0A8V0ZQ22-1|A0A8V0ZQ22_CHICK Isoform 1 of Eukaryotic 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factor 4B OS=Gallus gallus OX=9031 GN=EIF4B PE=1 SV=1 CANONICAL=A0A8V0ZQ22-1" }, "locus": { "chromosome": "34", "start_pos": 1891657, "end_pos": 1882024, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058461.1", "url": "https://www.ensembl.org/id/ENSGALT00010058461.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035527.1", "url": "https://www.ensembl.org/id/ENSGALP00010035527.1" } ] } }, { "isoform_ac": "A0A8V0ZQ29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ22/entry#A0A8V0ZQ29-1", "sequence": { "sequence": "MAASAKKKNKKGKTLTLTDFLAEDGGSGAPTYIPKPVSWADETDDLDGDGRVSTAWHSNDDDVYRAPLIDRSLLPTAPRAAREPNIDRSRLPKCPPYTAFLGNLPYDVTEDSIKDFFRGLNISAVRLPREPTNPERLKGFGYAEFEDIDSLFQALSLNEESLGNRRIRVDVADQAQDKDRDDRCFGRDRDRFRDSERFESDWRARPAASDSFDDFPPRRGDDAFGDRYRDRYDDRYRDGPRRDMDRGFGGRDRYDDRSRDYDRGYNSRIGSGRRAFGSGYRRDDDFRGGSDRYEERYERRDDRMERWGGRDDYGRDDFRREERGPTQRPKLNLKPRSAPKEEESTAAPAPQSSRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLEDDKRLERRPRERYPSSRSEDNPERSRTGSESSQSGAAGPPGTTAGTGPTGRTTRRRESEKSVEGDACGREEEGREEKQPLKVMPAPPPKENAWAKRSSSTAGRSPGSDSEQHSPSSSQMASRPPAENGAAPRSTHRRGDENKPDGGRDGPKARSGSSAERKDSRKEHEARAAPEPKRLEDSPAPFSHASKYAALSVDGEEEECGE", "length": 595, "header": "tr|A0A8V0ZQ29-1|A0A8V0ZQ29_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4B OS=Gallus gallus OX=9031 GN=EIF4B PE=1 SV=1 CANONICAL=A0A8V0ZQ22-1" }, "locus": { "chromosome": "34", "start_pos": 1893966, "end_pos": 1882024, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058467.1", "url": "https://www.ensembl.org/id/ENSGALT00010058467.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035532.1", "url": "https://www.ensembl.org/id/ENSGALP00010035532.1" } ] } }, { "isoform_ac": "A0A8V0ZVA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ22/entry#A0A8V0ZVA3-1", "sequence": { "sequence": "MQGTPRAPLDPHPSSPHPVATSGRGVVGCRQSPGADLATPPPPRPAAAKKKNKKGKTLTLTDFLAEDGGSGAPTYIPKPVSWADETDDLDGDGRVSTAWHSNDDDVYRAPLIDRSLLPTAPRAAREPNIDRSRLPKCPPYTAFLGNLPYDVTEDSIKDFFRGLNISAVRLPREPTNPERLKGFGYAEFEDIDSLFQALSLNEESLGNRRIRVDVADQAQDKDRDDRCFGRDRDRFRDSERFESDWRARPAASDSFDDFPPRRGDDAFGDRYRDRYDDRYRDGPRRDMDRGFGGRDRYDDRSRDYDRGYNSRIGSGRRAFGSGYRRDDDFRGGSDRYEERYERRDDRMERWGGRDDYGRDDFRREERGPTQRPKLNLKPRSAPKEEESTAAPAPQSSRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLEDDKRLERRPRERYPSSRSEDNPERSRTGSESSQSGAAGPPGTTAGTGPTGRTTRRRESEKSVEGDACGREEEGREEKQPLKAKRSSSTAGRSPGSDSEQHSPSSSQMASRPPAENGAAPRSTHRRGDENKPDGGRDGPKARSGSSAERKDSRKEHEARAAPEPKRLEDSPAPFSHASKYAALSVDGEEEECGE", "length": 626, "header": "tr|A0A8V0ZVA3-1|A0A8V0ZQ22_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4B OS=Gallus gallus OX=9031 GN=EIF4B PE=1 SV=1 CANONICAL=A0A8V0ZQ22-1" }, "locus": { "chromosome": "34", "start_pos": 1891657, "end_pos": 1882024, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058458.1", "url": "https://www.ensembl.org/id/ENSGALT00010058458.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035524.1", "url": "https://www.ensembl.org/id/ENSGALP00010035524.1" } ] } }, { "isoform_ac": "A0A8V0ZYY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ22/entry#A0A8V0ZYY0-1", "sequence": { "sequence": "MAAPKKNKKGKTLTLTDFLAEDGGSGAPTYIPKPVSWADETDDLDGDGRVSTAWHSNDDDVYRAPLIDRSLLPTAPRAAREPNIDRSRLPKCPPYTAFLGNLPYDVTEDSIKDFFRGLNISAVRLPREPTNPERLKGFGYAEFEDIDSLFQALSLNEEVSSGPQVSAAGQALMDLSRAGRTAGKGLKRGRTLTSGSPGEQNFDFRVPRRAEL", "length": 212, "header": "tr|A0A8V0ZYY0-1|A0A8V0ZQ22_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4B OS=Gallus gallus OX=9031 GN=EIF4B PE=1 SV=2 CANONICAL=A0A8V0ZQ22-1" }, "locus": { "chromosome": "34", "start_pos": 1892195, "end_pos": 1888756, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058450.1", "url": "https://www.ensembl.org/id/ENSGALT00010058450.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035520.1", "url": "https://www.ensembl.org/id/ENSGALP00010035520.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 482, "start_aa": "Thr", "end_pos": 482, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr482", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-166208", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-166208", "resource": "Reactome", "description": "mTORC1-mediated signalling" }, { "id": "R-GGA-429947", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-429947", "resource": "Reactome", "description": "Deadenylation of mRNA" }, { "id": "R-GGA-72649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72649", "resource": "Reactome", "description": "Translation initiation complex formation" }, { "id": "R-GGA-72702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-72702", "resource": "Reactome", "description": "Ribosomal scanning and start codon recognition" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", 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"pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQ22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ22" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 217, "start_aa": "Tyr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 482 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZQ33" } ] } ], "protein_names": [ { "name": "DDB1 and CUL4 associated factor 17", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ33/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ33" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DCAF17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ33", "locus": { "chromosome": "7", "start_pos": 17643668, "end_pos": 17662612, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022799", "url": "https://www.ensembl.org/id/ENSGALG00010022799" } ] } } ], "crossref": [ { "id": "A0A8V0ZQ33", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQ33", "database": "AlphaFoldDB", "categories": [] }, { "id": "424153", "url": "https://www.ncbi.nlm.nih.gov/gene/424153", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ33", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZSU2", "url": "https://www.orthodb.org/?gene=A0A8V0ZSU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14815", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14815", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14815:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14815:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15802", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15802", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQ33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZSU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLMFCRTGTCVRGIELLVSAIHTCNHQCEKTVPLPADAADNRQPFYFSYQSLESTKFKNVWTTHSASPIAYERGRIYLDNYRCCISSIAQEPRILYQKPKCSESEKIEDALLLECPLGEMLPNPSDYKPSLIVLTAQNWLLRLSADCGEILEKVYLAGSCCKFRYLSWDTPQEVMVVKSAQNKLPAEARQAGIQQSVLFHLAVFQVLPLSFIGMLEINKKIFGNSVTDVAISNGILIVMYSMGLVRLYNFQAISEQFMERPFDLGSEFNWNGEVGVVGKYPFGLPCNIKITDTPPLLFEASSLENAFQIGGFPWHYIITPNKKKHRGVFYICSLKDNALAKNGIQDMKCCSLEPDWIYFHPDMSGRIIHVGPNLIKVLKLKEVENNTDQIEIAEDFIITANRENCVNNSVTVTSSGRVVKKRINLLDDDPEQETFKIVDYEDELDLLSTVAVTEIGADGRAHLDLRCNEHGILLKSIPLRESWDVTYSHEVYFDRDIVLHIEQKPNRKFSCYVYQMVCDTAKEDECSRRERTERVSCKKGGRIFEYT", "length": 547, "header": "tr|A0A8V0ZQ33-1|A0A8V0ZQ33_CHICK Isoform 1 of DDB1 and CUL4 associated factor 17 OS=Gallus gallus OX=9031 GN=DCAF17 PE=4 SV=1 CANONICAL=A0A8V0ZQ33-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQ33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ33/entry#A0A8V0ZQ33-1", "sequence": { "sequence": "MLMFCRTGTCVRGIELLVSAIHTCNHQCEKTVPLPADAADNRQPFYFSYQSLESTKFKNVWTTHSASPIAYERGRIYLDNYRCCISSIAQEPRILYQKPKCSESEKIEDALLLECPLGEMLPNPSDYKPSLIVLTAQNWLLRLSADCGEILEKVYLAGSCCKFRYLSWDTPQEVMVVKSAQNKLPAEARQAGIQQSVLFHLAVFQVLPLSFIGMLEINKKIFGNSVTDVAISNGILIVMYSMGLVRLYNFQAISEQFMERPFDLGSEFNWNGEVGVVGKYPFGLPCNIKITDTPPLLFEASSLENAFQIGGFPWHYIITPNKKKHRGVFYICSLKDNALAKNGIQDMKCCSLEPDWIYFHPDMSGRIIHVGPNLIKVLKLKEVENNTDQIEIAEDFIITANRENCVNNSVTVTSSGRVVKKRINLLDDDPEQETFKIVDYEDELDLLSTVAVTEIGADGRAHLDLRCNEHGILLKSIPLRESWDVTYSHEVYFDRDIVLHIEQKPNRKFSCYVYQMVCDTAKEDECSRRERTERVSCKKGGRIFEYT", "length": 547, "header": "tr|A0A8V0ZQ33-1|A0A8V0ZQ33_CHICK Isoform 1 of DDB1 and CUL4 associated factor 17 OS=Gallus gallus OX=9031 GN=DCAF17 PE=4 SV=1 CANONICAL=A0A8V0ZQ33-1" }, "locus": { "chromosome": "7", "start_pos": 17661737, "end_pos": 17644194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055444.1", "url": "https://www.ensembl.org/id/ENSGALT00010055444.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033576.1", "url": "https://www.ensembl.org/id/ENSGALP00010033576.1" } ] } }, { "isoform_ac": "A0A8V0ZSU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ33/entry#A0A8V0ZSU2-1", "sequence": { "sequence": "MRPAVAGRAAPRAPNVCRLLGRRARGFYARDAGVALRKNMGLLRTILCQESTKFKNVWTTHSASPIAYERGRIYLDNYRCCISSIAQEPRILYQKPKCSESEKIEDALLLECPLGEMLPNPSDYKPSLIVLTAQNWLLRLSADCGEILEKVYLAGSCCKFRYLSWDTPQEVMVVKSAQNKLPAEARQAGIQQSVLFHLAVFQVLPLSFIGMLEINKKIFGNSVTDVAISNGILIVMYSMGLVRLYNFQAISEQFMERPFDLGSEFNWNGEVGVVGKYPFGLPCNIKITDTPPLLFEASSLENAFQIGGFPWHYIITPNKKKHRGVFYICSLKDNALAKNGIQDMKCCSLEPDWIYFHPDMSGRIIHVGPNLIKVLKLKEVENNTDQIEIAEDFIITANRENCVNNSVTVTSSGRVVKKRINLLDDDPEQETFKIVDYEDELDLLSTVAVTEIGADGRAHLDLRCNEHGILLKSIPLRESWDVTYSHEVYFDRDIVLHIEQKPNRKFSCYVYQMVCDTAKEDECSRRERTERVSCKKGGRIFEYT", "length": 544, "header": "tr|A0A8V0ZSU2-1|A0A8V0ZQ33_CHICK Computationally mapped isoform of DDB1 and CUL4 associated factor 17 OS=Gallus gallus OX=9031 GN=DCAF17 PE=4 SV=1 CANONICAL=A0A8V0ZQ33-1" }, "locus": { "chromosome": "7", "start_pos": 17662446, "end_pos": 17644194, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055445.1", "url": "https://www.ensembl.org/id/ENSGALT00010055445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033577.1", "url": "https://www.ensembl.org/id/ENSGALP00010033577.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ33" } ], "pmid": "" }, { "name": "Cul4-RING E3 ubiquitin ligase complex", "id": "GO:0080008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ33" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ33", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ33" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 385, "end_pos": 387 }, { "start_pos": 407, "end_pos": 409 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQ48-1", "uniprot_ac": "A0A8V0ZQ48", "uniprot_id": "A0A8V0ZQ48_CHICK", "mass": { "chemical_mass": 114431.0, "monoisotopic_mass": 114431.0 }, "refseq": {}, "gene_names": [ { "name": "A2ML1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48" } ] } ], "protein_names": [ { "name": "Alpha-2-macroglobulin like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "A2ML1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZQ48", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQ48", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ48", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXI9", "url": "https://www.orthodb.org/?gene=A0A8V0ZXI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412:SF182", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412:SF182", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07678", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07678", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZQ48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDREPGTVDLNYMRASHFIRPFYSTSRSFLSIVHVPEMMPCGKKQAIQVDFRIYQEDLEHGPKRVIFSYLVTGKSGIVHAGQKTVWVGLPRMLKGFFSIPVTFSSVYAPTSTLIVYVIFPNGKTIADSAVFSVSMCFRNKAELSFSVPKILPGSEVNLHLQAAPGSTCAVWAVDQTVFLLKPEKELSHSMIYGLFPSIPSTYSGYPHQVSEDDNSCGFQNSDQPDVFTAFREMGLKIMSNTNIRKPRLCLTTQSTTMMQERGMFTSRPMLMFAQPHKESNTGHLMTSTYQPTMFSPVSSPEEKVHKYFTKTWLWDLYSVGPSGKQTVTVTVPNTITGWKAGMFCTGHNGFGLAPTSSLLVFKPFSVELTLPSSVIQGETFILKATVLSYLQQCMKIQVTMEEFPQFQLKSCEGCVYSSCLCAGEVRTFLWSVTAERLGFTNITLSTEAIATKELCGKEIPFVPNQGQKDTITKLLLVRPEGVLIEKAHSSILCPKKGSPAEESVSLTLPPNTVEGSVRATVSVTGDLMGTALQNLDHLVQMPHGCGEQNMVLFAPIVYMLQYLEKTRQLTPEIKERATGFLRNGYQIQLQYQHPDGSFSEFGTKDEYGNTWLTAFVVKCFAQAKPYIFLDDRSIQAAFNWLEFHQLPNGCFRDVGQLFHTAMKGGMDGEVLLAAYITAAYMERGDTPESTVVRKALGCIIPSLPKATSTYTQALLAYTFALAKDPQRTQELLDILDEKAIRAGGQIHWSQTPSKAHSTSLWSQPLSVDVELTAYVLLALLSKPNVTEADFTIASGIVAWLTRQQNAYGGFASTQDTVVALQALAKYAALTHNTKGVAEVRVRSQRGSGRKFQVSYHNRLLVQEMALREIPGKFSVQAHGSCCVFTRTVLRYNIPFPQVSKSFALQVKTKPDNCTEDDAYSVTLYVNVRYTGKRAISNMVIVEVSLLSGFVLAARSGMSPHHWYPVRRTEKTQAGVAIYLDKLSHVSETYVLHLEREIEVTNLKPGQVRVYDYYHPEEQALADYNVSCI", "length": 1028, "header": "tr|A0A8V0ZQ48-1|A0A8V0ZQ48_CHICK Isoform 1 of Alpha-2-macroglobulin like 1 OS=Gallus gallus OX=9031 GN=A2ML1 PE=1 SV=1 CANONICAL=A0A8V0ZQ48-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQ48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48/entry#A0A8V0ZQ48-1", "sequence": { "sequence": "MDREPGTVDLNYMRASHFIRPFYSTSRSFLSIVHVPEMMPCGKKQAIQVDFRIYQEDLEHGPKRVIFSYLVTGKSGIVHAGQKTVWVGLPRMLKGFFSIPVTFSSVYAPTSTLIVYVIFPNGKTIADSAVFSVSMCFRNKAELSFSVPKILPGSEVNLHLQAAPGSTCAVWAVDQTVFLLKPEKELSHSMIYGLFPSIPSTYSGYPHQVSEDDNSCGFQNSDQPDVFTAFREMGLKIMSNTNIRKPRLCLTTQSTTMMQERGMFTSRPMLMFAQPHKESNTGHLMTSTYQPTMFSPVSSPEEKVHKYFTKTWLWDLYSVGPSGKQTVTVTVPNTITGWKAGMFCTGHNGFGLAPTSSLLVFKPFSVELTLPSSVIQGETFILKATVLSYLQQCMKIQVTMEEFPQFQLKSCEGCVYSSCLCAGEVRTFLWSVTAERLGFTNITLSTEAIATKELCGKEIPFVPNQGQKDTITKLLLVRPEGVLIEKAHSSILCPKKGSPAEESVSLTLPPNTVEGSVRATVSVTGDLMGTALQNLDHLVQMPHGCGEQNMVLFAPIVYMLQYLEKTRQLTPEIKERATGFLRNGYQIQLQYQHPDGSFSEFGTKDEYGNTWLTAFVVKCFAQAKPYIFLDDRSIQAAFNWLEFHQLPNGCFRDVGQLFHTAMKGGMDGEVLLAAYITAAYMERGDTPESTVVRKALGCIIPSLPKATSTYTQALLAYTFALAKDPQRTQELLDILDEKAIRAGGQIHWSQTPSKAHSTSLWSQPLSVDVELTAYVLLALLSKPNVTEADFTIASGIVAWLTRQQNAYGGFASTQDTVVALQALAKYAALTHNTKGVAEVRVRSQRGSGRKFQVSYHNRLLVQEMALREIPGKFSVQAHGSCCVFTRTVLRYNIPFPQVSKSFALQVKTKPDNCTEDDAYSVTLYVNVRYTGKRAISNMVIVEVSLLSGFVLAARSGMSPHHWYPVRRTEKTQAGVAIYLDKLSHVSETYVLHLEREIEVTNLKPGQVRVYDYYHPEEQALADYNVSCI", "length": 1028, "header": "tr|A0A8V0ZQ48-1|A0A8V0ZQ48_CHICK Isoform 1 of Alpha-2-macroglobulin like 1 OS=Gallus gallus OX=9031 GN=A2ML1 PE=1 SV=1 CANONICAL=A0A8V0ZQ48-1" }, "locus": { "chromosome": "1", "start_pos": 76074454, "end_pos": 76052939, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055459.1", "url": "https://www.ensembl.org/id/ENSGALT00010055459.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033586.1", "url": "https://www.ensembl.org/id/ENSGALP00010033586.1" } ] } }, { "isoform_ac": "A0A8V0ZXI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48/entry#A0A8V0ZXI9-1", "sequence": { "sequence": "MDREPGTVDLNYMRASHFIRPFYSTSRSFLSIVHVPEMMPCGKKQAIQVDFRIYQEDLEHGPKRVIFSYLVTGKSGIVHAGQKTVWVGLPRMLKGFFSIPVTFSSVYAPTSTLIVYVIFPNGKTIADSAVFSVSMCFRNKAELSFSVPKILPGSEVNLHLQAAPGSTCAVWAVDQTVFLLKPEKELSHSMIYGLFPSIPSTYSGYPHQVSEDDNSCGFQNSDQPDVFTAFREMGLKIMSNTNIRKPRLCLTTQSTTMMQERGMFTSRPMLMFAQPHKESNTGHLMTSTYQPTMFSPVSSPEEKVHKYFTKTWLWDLYSVGPSGKQTVTVTVPNTITGWKAGMFCTGHNGFGLAPTSSLLVFKPFSVELTLPSSVIQGETFILKATVLSYLQQCMKIQVTMEEFPQFQLKSCEGCVYSSCLCAGEVRTFLWSVTAERLGFTNITLSTEAIATKELCGKEIPFVPNQGQKDTITKLLLVRPEGVLIEKAHSSILCPKKGSPAEESVSLTLPPNTVEGSVRATVSVTGDLMGTALQNLDHLVQMPHGCGEQNMVLFAPIVYMLQYLEKTRQLTPEIKERATGFLRNGYQIQLQYQHPDGSFSEFGTKDEYGNTWLTAFVVKCFAQAKPYIFLDDRSIQAAFNWLEFHQLPNGCFRDVGQLFHTAMKGGMDGEVLLAAYITAAYMERGDTPESTVVRKALGCIIPSLPKATSTYTQALLAYTFALAKDPQRTQELLDILDEKAIRAGGQIHWSQTPSKAHSTSLWSQPLSVDVELTAYVLLALLSKPNVTEADFTIASGIVAWLTRQQNAYGGFASTQDTVVALQALAKYAALTHNTKGVAEVRVRSQRGSGRKFQVSYHNRLLVQEMALREIPGKFSVQAHGSCCVFTRVGYPLPMDFSVSALCSSSKLIVSVPALYKEMRFNCALLPACCQCSKPVCYSRLRHNVSKSVASMILGVLEDGNLA", "length": 961, "header": "tr|A0A8V0ZXI9-1|A0A8V0ZQ48_CHICK Computationally mapped isoform of Alpha-2-macroglobulin like 1 OS=Gallus gallus OX=9031 GN=A2ML1 PE=1 SV=1 CANONICAL=A0A8V0ZQ48-1" }, "locus": { "chromosome": "1", "start_pos": 76072668, "end_pos": 76052939, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055463.1", "url": "https://www.ensembl.org/id/ENSGALT00010055463.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033590.1", "url": "https://www.ensembl.org/id/ENSGALP00010033590.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1024, "end_pos": 1026, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 784, "end_pos": 786, "annotation": "n_glycosylation_sequon" }, { "start_pos": 912, "end_pos": 914, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQ48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48" }, { "id": "SM01360", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01360" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-2-macroglobulin", "eco_id": "ECO_0000259", "start_pos": 311, "end_pos": 400, "start_aa": "Thr", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQ48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48" }, { "id": "SM01359", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01359" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-2-macroglobulin bait region", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 180, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQ48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ48" }, { "id": "SM01361", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01361" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-macroglobulin receptor-binding", "eco_id": "ECO_0000259", "start_pos": 936, "end_pos": 1023, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1024, "end_pos": 1026 }, { "start_pos": 441, "end_pos": 443 }, { "start_pos": 784, "end_pos": 786 }, { "start_pos": 912, "end_pos": 914 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQ81-1", "uniprot_ac": "A0A8V0ZQ81", "uniprot_id": "A0A8V0ZQ81_CHICK", "mass": { "chemical_mass": 32546.0, "monoisotopic_mass": 32546.0 }, "refseq": {}, "gene_names": [ { "name": "CD86", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ81" } ] } ], "protein_names": [ { "name": "CD86 molecule", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQ81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ81/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ81" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD86", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ81", "locus": { "chromosome": "1", "start_pos": 76601433, "end_pos": 76586198, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021372", "url": "https://www.ensembl.org/id/ENSGALG00010021372" } ] } } ], "crossref": [ { "id": "A0A8V0ZQ81", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQ81", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ76", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ81", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25466", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25466", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25466:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25466:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1257604", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1257604", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-389356", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389356", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-389357", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389357", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-389359", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389359", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-389513", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-389513", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6811558", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6811558", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQ76", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ81", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPALQPPSGRQQPGNSVGPLRLLSSASKLTHKESIMEVCIFFLYAIILLPGIAANVHHVKSFLNHTAYLSCYFPNSQKTDINNVIVFWQKGTGEVVHEVYLGQEKHDHLNSKYINRTKMDMDKWTLQLLNVGIVDEGQYKCIIMHVDKGPKKLIHESECLLNITANYSQPVIAQLHTGEPKPNENLNLSCSSSGGYPEPKQMIWLISSENITDRLIRHMDVLQDAVTKLYNVTSKLNIPVPTNTLTNISCLLHLGEQQGSLVSVPLVIEIPAEEMEPVKVSVSQSKRYPA", "length": 291, "header": "tr|A0A8V0ZQ81-1|A0A8V0ZQ81_CHICK Isoform 1 of CD86 molecule OS=Gallus gallus OX=9031 GN=CD86 PE=4 SV=1 CANONICAL=A0A8V0ZQ81-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQ76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ81/entry#A0A8V0ZQ76-1", "sequence": { "sequence": "EEVCIAANVHHVKSFLNHTAYLSCYFPNSQKTDINNVIVFWQKGTGEVVHEVYLGQEKHDHLNSKYINRTKMDMDKWTLQLLNVGIVDEGQYKCIIMHVDKGPKKLIHESECLLNITANYSQPVIAQLHTGEPKPNENLNLSCSSSGGYPEPKQMIWLISSENITDRLIRHMDVLQDAVTKLYNVTSKLNIPVPTNTLTNISCLLHLGEQQGSLVSVPLVIEIPAEEMEPVKVNFFGPLVAVILLVTLLLGFLILKNRNISSTSQSVSLAV", "length": 271, "header": "tr|A0A8V0ZQ76-1|A0A8V0ZQ81_CHICK Computationally mapped isoform of CD86 molecule OS=Gallus gallus OX=9031 GN=CD86 PE=4 SV=1 CANONICAL=A0A8V0ZQ81-1" }, "locus": { "chromosome": "1", "start_pos": 76600413, "end_pos": 76593202, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051781.1", "url": "https://www.ensembl.org/id/ENSGALT00010051781.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030888.1", "url": "https://www.ensembl.org/id/ENSGALP00010030888.1" } ] } }, { "isoform_ac": "A0A8V0ZQ81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ81/entry#A0A8V0ZQ81-1", "sequence": { "sequence": "MQPALQPPSGRQQPGNSVGPLRLLSSASKLTHKESIMEVCIFFLYAIILLPGIAANVHHVKSFLNHTAYLSCYFPNSQKTDINNVIVFWQKGTGEVVHEVYLGQEKHDHLNSKYINRTKMDMDKWTLQLLNVGIVDEGQYKCIIMHVDKGPKKLIHESECLLNITANYSQPVIAQLHTGEPKPNENLNLSCSSSGGYPEPKQMIWLISSENITDRLIRHMDVLQDAVTKLYNVTSKLNIPVPTNTLTNISCLLHLGEQQGSLVSVPLVIEIPAEEMEPVKVSVSQSKRYPA", "length": 291, "header": "tr|A0A8V0ZQ81-1|A0A8V0ZQ81_CHICK Isoform 1 of CD86 molecule OS=Gallus gallus OX=9031 GN=CD86 PE=4 SV=1 CANONICAL=A0A8V0ZQ81-1" }, "locus": { "chromosome": "1", "start_pos": 76600429, "end_pos": 76590238, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010051789.1", "url": "https://www.ensembl.org/id/ENSGALT00010051789.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010030893.1", "url": "https://www.ensembl.org/id/ENSGALP00010030893.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": 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"categories": [ "Protein Classification" ] }, { "id": "IPR047944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424752", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424752", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FHEHCFV", "url": "https://omabrowser.org/oma/group/FHEHCFV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ80", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQ85", "url": "https://www.orthodb.org/?gene=A0A8V0ZQ85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVF1", "url": "https://www.orthodb.org/?gene=A0A8V0ZVF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVG1", "url": "https://www.orthodb.org/?gene=A0A8V0ZVG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVG5", "url": "https://www.orthodb.org/?gene=A0A8V0ZVG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A2V8", "url": "https://www.orthodb.org/?gene=A0A8V1A2V8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24210", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24210", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24210:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24210:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZQ80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQ85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVG1-1", "url": 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"MVAAVCPPGGGRGGGPPGLRVLSGRCTPSVVVAFRVCGAVMGCGCNMSDALANAVCERCQTRFDPAERIVNSNGELYHENCFVCAQCFRQFPDGLFYEFEGRKYCEHDFQMLFAPCCGECGEFIIGRVIKAMNNNWHPECFRCELCDVALADLGFVKNAGRHLCRPCHNREKAKGLGKYICQKCHLIIDEQPLMFRNDSYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGIPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVNCFSCSTCNIKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLSELASKKAHPKALDLNSA", "length": 382, "header": "tr|A0A8V0ZQ85-1|A0A8V0ZQ85_CHICK Isoform 1 of LIM domain-containing protein OS=Gallus gallus OX=9031 GN=LIMS2 PE=1 SV=1 CANONICAL=A0A8V0ZQ85-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQ80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85/entry#A0A8V0ZQ80-1", "sequence": { "sequence": "MCSFKALRLSNLLVLNMSDALANAVCERCQTRFDPAERIVNSNGELYHENCFVCAQCFRQFPDGLFYEFEGRKYCEHDFQMLFAPCCGECGEFIIGRVIKAMNNNWHPECFRCELCDVALADLGFVKNAGRHLCRPCHNREKAKGLGKYICQKCHLIIDEQPLMFRNDSYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGIPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVNCFSCSTCNIKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLSELASKKAHPKALDLNSA", "length": 352, "header": "tr|A0A8V0ZQ80-1|A0A8V0ZQ85_CHICK Computationally mapped isoform of LIM domain-containing protein OS=Gallus gallus OX=9031 GN=LIMS2 PE=1 SV=1 CANONICAL=A0A8V0ZQ85-1" }, "locus": { "chromosome": "9", "start_pos": 1019433, "end_pos": 1000315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058539.1", "url": "https://www.ensembl.org/id/ENSGALT00010058539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035582.1", "url": "https://www.ensembl.org/id/ENSGALP00010035582.1" } ] } }, { "isoform_ac": "A0A8V0ZQ85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85/entry#A0A8V0ZQ85-1", "sequence": { "sequence": "MVAAVCPPGGGRGGGPPGLRVLSGRCTPSVVVAFRVCGAVMGCGCNMSDALANAVCERCQTRFDPAERIVNSNGELYHENCFVCAQCFRQFPDGLFYEFEGRKYCEHDFQMLFAPCCGECGEFIIGRVIKAMNNNWHPECFRCELCDVALADLGFVKNAGRHLCRPCHNREKAKGLGKYICQKCHLIIDEQPLMFRNDSYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGIPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVNCFSCSTCNIKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLSELASKKAHPKALDLNSA", "length": 382, "header": "tr|A0A8V0ZQ85-1|A0A8V0ZQ85_CHICK Isoform 1 of LIM domain-containing protein OS=Gallus gallus OX=9031 GN=LIMS2 PE=1 SV=1 CANONICAL=A0A8V0ZQ85-1" }, "locus": { "chromosome": "9", "start_pos": 1021917, "end_pos": 1000315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058544.1", "url": "https://www.ensembl.org/id/ENSGALT00010058544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035587.1", "url": "https://www.ensembl.org/id/ENSGALP00010035587.1" } ] } }, { "isoform_ac": "A0A8V0ZVF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85/entry#A0A8V0ZVF1-1", "sequence": { "sequence": "MGLCSSAEGTGDRKISIEGAKKHSSKAGKQCRLMMGRVSNMSDALANAVCERCQTRFDPAERIVNSNGELYHENCFVCAQCFRQFPDGLFYEFEGRKYCEHDFQMLFAPCCGECGEFIIGRVIKAMNNNWHPECFRCELCDVALADLGFVKNAGRHLCRPCHNREKAKGLGKYICQKCHLIIDEQPLMFRNDSYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGIPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVNCFSCSTCNIKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLSELASKKAHPKALDLNSA", "length": 376, "header": "tr|A0A8V0ZVF1-1|A0A8V0ZQ85_CHICK Computationally mapped isoform of LIM domain-containing protein OS=Gallus gallus OX=9031 GN=LIMS2 PE=1 SV=1 CANONICAL=A0A8V0ZQ85-1" }, "locus": { "chromosome": "9", "start_pos": 1018814, "end_pos": 1000315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058528.1", "url": "https://www.ensembl.org/id/ENSGALT00010058528.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035574.1", "url": "https://www.ensembl.org/id/ENSGALP00010035574.1" } ] } }, { "isoform_ac": "A0A8V0ZVG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85/entry#A0A8V0ZVG1-1", "sequence": { "sequence": "MASLRLQDPAASGLYWRRWGRARMATMARGNMSDALANAVCERCQTRFDPAERIVNSNGELYHENCFVCAQCFRQFPDGLFYEFEGRKYCEHDFQMLFAPCCGECGEFIIGRVIKAMNNNWHPECFRCELCDVALADLGFVKNAGRHLCRPCHNREKAKGLGKYICQKCHLIIDEQPLMFRNDSYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGIPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVNCFSCSTCNIKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLSELASKKAHPKALDLNSA", "length": 367, "header": "tr|A0A8V0ZVG1-1|A0A8V0ZQ85_CHICK Computationally mapped isoform of LIM domain-containing protein OS=Gallus gallus OX=9031 GN=LIMS2 PE=1 SV=1 CANONICAL=A0A8V0ZQ85-1" }, "locus": { "chromosome": "9", "start_pos": 1019839, "end_pos": 1000315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058541.1", "url": "https://www.ensembl.org/id/ENSGALT00010058541.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035584.1", "url": "https://www.ensembl.org/id/ENSGALP00010035584.1" } ] } }, { "isoform_ac": "A0A8V0ZVG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85/entry#A0A8V0ZVG5-1", "sequence": { "sequence": "MTGSNMSDALANAVCERCQTRFDPAERIVNSNGELYHENCFVCAQCFRQFPDGLFYEFEGRKYCEHDFQMLFAPCCGECGEFIIGRVIKAMNNNWHPECFRCELCDVALADLGFVKNAGRHLCRPCHNREKAKGLGKYICQKCHLIIDEQPLMFRNDSYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGIPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVNCFSCSTCNIKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLSELASKKAHPKALDLNSA", "length": 341, "header": "tr|A0A8V0ZVG5-1|A0A8V0ZQ85_CHICK Computationally mapped isoform of LIM domain-containing protein OS=Gallus gallus OX=9031 GN=LIMS2 PE=1 SV=1 CANONICAL=A0A8V0ZQ85-1" }, "locus": { "chromosome": "9", "start_pos": 1022032, "end_pos": 1000315, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058548.1", "url": "https://www.ensembl.org/id/ENSGALT00010058548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035589.1", "url": "https://www.ensembl.org/id/ENSGALP00010035589.1" } ] } }, { "isoform_ac": "A0A8V1A2V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85/entry#A0A8V1A2V8-1", "sequence": { "sequence": "MSDALANAVCERCQTRFDPAERIVNSNGELYHENCFVCAQCFRQFPDGLFYEFEGRKYCEHDFQMLFAPCCGECGEFIIGRVIKAMNNNWHPECFRCELCDVALADLGFVKNAGRHLCRPCHNREKAKGLGKYICQKCHLIIDEQPLMFRNDSYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGIPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVNCFSCSTCNIKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLETTEKWYLALLLVTQPAS", "length": 336, "header": "tr|A0A8V1A2V8-1|A0A8V0ZQ85_CHICK Computationally mapped isoform of LIM domain-containing protein OS=Gallus gallus OX=9031 GN=LIMS2 PE=1 SV=1 CANONICAL=A0A8V0ZQ85-1" }, "locus": { "chromosome": "9", "start_pos": 1015438, "end_pos": 1000164, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058535.1", "url": "https://www.ensembl.org/id/ENSGALT00010058535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035578.1", "url": "https://www.ensembl.org/id/ENSGALP00010035578.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424752", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424752", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GK29-1", "protein_name": "LIM and senescent cell antigen-like-containing domain protein", "gene_name": "Lims2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSECLADAMCQRCQARFAPTERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGFCGEFVIGRVIKAMNANWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKFICQRCHLAIDEQPLMFKNDPYHPDHFSCSHCGKELTSDARELKGELYCLPCHDKMGIPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALSKAWCVNCFSCSACNMKLTLKNKFVEFDMKPVCKRCYERFPLELKKRLKKLSDLSSRKAQPKPVGVNSV", "length": 336 }, "evidence": [ { "id": "A0A8V0ZQ85", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ85/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KJ33-1", "protein_name": "LIM and senescent cell antigen-like-containing domain protein 2", "gene_name": "LIMS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGSNMSNALANAVCQRCQARFAPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFKNDAYHPDHFSCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYTCSHVIEGDVVSALNKAWCVHCFSCSTCNSRLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELAARRAQPKSSGLHPA", "length": 341 }, "evidence": [ { "id": "A0A8V0ZQ85", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ85/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7Z4I7-1", "protein_name": "LIM and senescent cell antigen-like-containing domain protein 2", "gene_name": "LIMS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTGSNMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKATDLNSA", "length": 341 }, "evidence": [ { "id": "A0A8V0ZQ85", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ85/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91XD2-1", "protein_name": "LIM and senescent cell antigen-like-containing domain protein 2", "gene_name": "Lims2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGSNMSECLADAMCQRCQARFAPTERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGFCGEFVIGRVIKAMNANWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKFICQRCHLAIDEQPLMFKNDPYHPDHFSCSNCGKELTSDARELKGELYCLPCHDKMGIPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALSKAWCVNCFSCSTCNMKLTLKNKFVEFDMKPVCKRCYERFPLELKKRLKKLSDLSSRKAQPKSVDVNSL", "length": 341 }, "evidence": [ { "id": "A0A8V0ZQ85", "url": "https://omabrowser.org/oma/group/A0A8V0ZQ85/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85" } ], "pmid": "" }, { "name": "positive regulation of integrin-mediated signaling pathway", "id": "GO:2001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85" } ], "pmid": "" }, { "name": "cell-cell junction organization", "id": "GO:0045216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQ85", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQ85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ85" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 115, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 206, "end_pos": 208 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQB8-1", "uniprot_ac": "A0A8V0ZQB8", "uniprot_id": "A0A8V0ZQB8_CHICK", "mass": { "chemical_mass": 144975.0, "monoisotopic_mass": 144975.0 }, "refseq": {}, "gene_names": [ { "name": "MYBPC3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ] } ], "protein_names": [ { "name": "Myosin-binding protein C, cardiac-type", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8/entry#names_and_taxonomy" } ] }, { "name": "C-protein, cardiac muscle isoform", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MYBPC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8", "locus": { "chromosome": "5", "start_pos": 22571019, "end_pos": 22512390, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022468", "url": "https://www.ensembl.org/id/ENSGALG00010022468" } ] } } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396013", "url": "https://www.ncbi.nlm.nih.gov/gene/396013", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QFDGGQP", "url": "https://omabrowser.org/oma/group/QFDGGQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQA8", "url": "https://www.orthodb.org/?gene=A0A8V0ZQA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQB8", "url": "https://www.orthodb.org/?gene=A0A8V0ZQB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVZ0", "url": "https://www.orthodb.org/?gene=A0A8V0ZVZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13817", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13817", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13817:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13817:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18362", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18362", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-390522", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390522", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQA8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKYRERCAIYAQLSILHLLPKDSRFNWEFHQEVKMPEPAKKAVSAFTKKPKTTEVAAGSTAVFEAETEKTGIKVKWQRAGTEITDSEKYAIKAEGNKHSLTISNVGKDDEVTYAVIAGTSKVKFELKVKEPEKSEPVAPAEASPAPAASELPAPPVESNQNPEVPPAETQPEEPVDPIGLFVTRPQDGEVTVGGNITFTAKVAGESLLKKPSVKWFKGKWMDLASKVGKHLQLHDNYDRNNKVYTFEMEIIEANMTFAGGYRCEVSTKDKFDSSNFNLIVNEAPVSGEMDIRAAFRRTTEGLEESGELNFSALLKKSSFLRTANRGDGKSDSQPDVDVWEILRKAPPSEYEKIAFQYGITDLRGMLKRLKRIKKEEKKSTAFLKKLDPAYQVDKGQKIKLMVEVANPDADVKWLKNGQEIQVSGSKYIFEAIGNKRILTINHCSLADDAAYECVVAEEKSFTELFVKEPPILITHPLEDQMVMVGERVEFECEVSEEGATVKWEKDGVELTREETFKYRFKKDGKKQYLIINESTKEDSGHYTVKTNGGVSVAELIVQEKKLEVYQSIADLTVKARDQAVFKCEVSDENVKGIWLKNGKEVVPDERIKISHIGRIHKLTIEDVTPGDEADYSFIPQGFAYNLSAKLQFLEVKIDFVPREEPPKIHLDCLGQSPDTIVVVAGNKLRLDVPISGDPTPTVIWQKVNKKGELVHQSNEDSLTPSENSSDLSTDSKLLFESEGRVRVEKHEDHCVFIIEGAEKEDEGVYRVIVKNPVGEDKADITVKVIDVPDPPEAPKISNIGEDYCTVQWQPPTYDGGQPVLGYILERKKKKSYRWMRLNFDLLKELTYEAKRMIEGVVYEMRIYAVNSIGMSRPSPASQPFMPIAPPSEPTHFTVEDVSDTTVALKWRPPERIGAGGLDGYIVEYCKDGSAEWTPALPGLTERTSALIKDLVTGDKLYFRVKAINLAGESGAAIIKEPVTVQEIMQRPKIWLPRHLRQTLVKKVGETINIMIPFQGKPRPKISWMKDGQTLDSKDVGIRNSSTDTILFIRKAELHHSGAYEVTLQIENMTDTVAITIQIIDKPGPPQNIKLADVWGFNVALEWTPPQDDGNAQILGYTVQKADKKTMEWYTVYDHYRRTNCVVSDLIMGNEYFFRVFSENLCGLSETAATTKNPAYIQKTGTTYKPPSYKEHDFSEPPKFTHPLVNRSVIAGYNTTLSCAVRGIPKPKIFWYKNKVDLSGDAKYRMFSKQGVLTLEIRKPTPFDGGFYTCKAVNERGEAEIECRLDVRVPQ", "length": 1290, "header": "tr|A0A8V0ZQB8-1|A0A8V0ZQB8_CHICK Isoform 1 of Myosin-binding protein C, cardiac-type OS=Gallus gallus OX=9031 GN=MYBPC3 PE=3 SV=1 CANONICAL=A0A8V0ZQB8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8/entry#A0A8V0ZQA8-1", "sequence": { "sequence": "TAVFEAETEKTGIKVKWQRAGTEITDSEKYAIKAEGNKHSLTISNVGKDDEVTYAVIAGTSKVKFELKVKEPEKSEPVAPAEASPAPAASELPAPPVESNQNPEVPPAETQPEEPVDPIGLFVTRPQDGEVTVGGNITFTAKVAGESLLKKPSVKWFKGKWMDLASKVGKHLQLHDNYDRNNKVYTFEMEIIEANMTFAGGYRCEVSTKDKFDSSNFNLIVNEAPVSGEMDIRAAFRLFLLLHSTEGLEESGELNFSALLKKRNGFILFCRGDGKSDSQPDVDVWEILRKAPPSEYEKIAFQYGITDLRGMLKRLKRIKKEEKKSTAFLKKLDPAYQVDKGQKIKLMVEVANPDADVKWLKNGQEIQVSGRYIFEAIGNKRILTINHCSLADDAAYECVVAEEKSFTELFVKEPPILITHPLEDQMVMVGERVEFECEVSEEGATVKWEKDGVELTREETFKYRFKKDGKKQYLIINESTKEDSGHYTVKTNGGVSVAELIVQEKKLEVYQSIADLTVKARDQAVFKCEVSDENVKGIWLKNGKEVVPDERIKISHIGRIHKLTIEDVTPGDEADYSFIPQGFAYNLSAKLQFLEVKIDFVPREEPPKIHLDCLGQSPDTIVVVAGNKLRLDVPISGDPTPTVIWQKVNKKGELVHQSNEDSLTPSENSSDLSTDSKLLFESEGRVRVEKHEDHCVFIIEGAEKEDEGVYRVIVKNPVGEDKADITVKVIDVPDPPEAPKISNIGEDYCTVQWQPPTYDGGQPVLGYILERKKKKSYRWMRLNFDLLKELTYEAKRMIEGVVYEMRIYAVNSIGMSRPSPASQPFMPIAPPSEPTHFTVEDVSDTTVALKWRPPERIGAGGLDGYIVEYCKDGSAEWTPALPGLTERTSALIKDLVTGDKLYFRVKAINLAGESGAAIIKEPVTVQEIMQRPKIWLPRHLRQTLVKKVGETINIMIPFQGKPRPKISWMKDGQTLDSKDVGIRNSSTDTILFIRKAELHHSGAYEVTLQIENMTDTVAITIQIIDKPGPPQNIKLADVWGFNVALEWTPPQDDGNAQILGYTVQKADKKTMEWYTVYDHYRRTNCVVSDLIMGNEYFFRVFSENLCGLSETAATTKNPAYIQKTGTTYKPPSYKEHDFSEPPKFTHPLVNRSVIAGYNTTLSCAVRGIPKPKIFWYKNKVDLSGDAKYRMFSKQGVLTLEIRKPTPFDGGFYTCKAVNERGEAEIECRLDVRGNQINIMDNINFAGKNQQ", "length": 1250, "header": "tr|A0A8V0ZQA8-1|A0A8V0ZQB8_CHICK Computationally mapped isoform of Myosin-binding protein C, cardiac-type OS=Gallus gallus OX=9031 GN=MYBPC3 PE=3 SV=1 CANONICAL=A0A8V0ZQB8-1" }, "locus": { "chromosome": "5", "start_pos": 22568252, "end_pos": 22522255, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054655.1", "url": "https://www.ensembl.org/id/ENSGALT00010054655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033016.1", "url": "https://www.ensembl.org/id/ENSGALP00010033016.1" } ] } }, { "isoform_ac": "A0A8V0ZQB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8/entry#A0A8V0ZQB8-1", "sequence": { "sequence": "MKYRERCAIYAQLSILHLLPKDSRFNWEFHQEVKMPEPAKKAVSAFTKKPKTTEVAAGSTAVFEAETEKTGIKVKWQRAGTEITDSEKYAIKAEGNKHSLTISNVGKDDEVTYAVIAGTSKVKFELKVKEPEKSEPVAPAEASPAPAASELPAPPVESNQNPEVPPAETQPEEPVDPIGLFVTRPQDGEVTVGGNITFTAKVAGESLLKKPSVKWFKGKWMDLASKVGKHLQLHDNYDRNNKVYTFEMEIIEANMTFAGGYRCEVSTKDKFDSSNFNLIVNEAPVSGEMDIRAAFRRTTEGLEESGELNFSALLKKSSFLRTANRGDGKSDSQPDVDVWEILRKAPPSEYEKIAFQYGITDLRGMLKRLKRIKKEEKKSTAFLKKLDPAYQVDKGQKIKLMVEVANPDADVKWLKNGQEIQVSGSKYIFEAIGNKRILTINHCSLADDAAYECVVAEEKSFTELFVKEPPILITHPLEDQMVMVGERVEFECEVSEEGATVKWEKDGVELTREETFKYRFKKDGKKQYLIINESTKEDSGHYTVKTNGGVSVAELIVQEKKLEVYQSIADLTVKARDQAVFKCEVSDENVKGIWLKNGKEVVPDERIKISHIGRIHKLTIEDVTPGDEADYSFIPQGFAYNLSAKLQFLEVKIDFVPREEPPKIHLDCLGQSPDTIVVVAGNKLRLDVPISGDPTPTVIWQKVNKKGELVHQSNEDSLTPSENSSDLSTDSKLLFESEGRVRVEKHEDHCVFIIEGAEKEDEGVYRVIVKNPVGEDKADITVKVIDVPDPPEAPKISNIGEDYCTVQWQPPTYDGGQPVLGYILERKKKKSYRWMRLNFDLLKELTYEAKRMIEGVVYEMRIYAVNSIGMSRPSPASQPFMPIAPPSEPTHFTVEDVSDTTVALKWRPPERIGAGGLDGYIVEYCKDGSAEWTPALPGLTERTSALIKDLVTGDKLYFRVKAINLAGESGAAIIKEPVTVQEIMQRPKIWLPRHLRQTLVKKVGETINIMIPFQGKPRPKISWMKDGQTLDSKDVGIRNSSTDTILFIRKAELHHSGAYEVTLQIENMTDTVAITIQIIDKPGPPQNIKLADVWGFNVALEWTPPQDDGNAQILGYTVQKADKKTMEWYTVYDHYRRTNCVVSDLIMGNEYFFRVFSENLCGLSETAATTKNPAYIQKTGTTYKPPSYKEHDFSEPPKFTHPLVNRSVIAGYNTTLSCAVRGIPKPKIFWYKNKVDLSGDAKYRMFSKQGVLTLEIRKPTPFDGGFYTCKAVNERGEAEIECRLDVRVPQ", "length": 1290, "header": "tr|A0A8V0ZQB8-1|A0A8V0ZQB8_CHICK Isoform 1 of Myosin-binding protein C, cardiac-type OS=Gallus gallus OX=9031 GN=MYBPC3 PE=3 SV=1 CANONICAL=A0A8V0ZQB8-1" }, "locus": { "chromosome": "5", "start_pos": 22569385, "end_pos": 22512395, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054666.1", "url": "https://www.ensembl.org/id/ENSGALT00010054666.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033026.1", "url": "https://www.ensembl.org/id/ENSGALP00010033026.1" } ] } }, { "isoform_ac": "A0A8V0ZVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8/entry#A0A8V0ZVZ0-1", "sequence": { "sequence": "MPEPAKKAVSAFTKKPKTTEVAAGSTAVFEAETEKTGIKVKWQRAGTEITDSEKYAIKAEGNKHSLTISNVGKDDEVTYAVIAGTSKVKFELKVKEPEKSEPVAPAEASPAPAASELPAPPVESNQNPEVPPAETQPEEPVDPIGLFVTRPQDGEVTVGGNITFTAKVAGESLLKKPSVKWFKGKWMDLASKVGKHLQLHDNYDRNNKVYTFEMEIIEANMTFAGGYRCEVSTKDKFDSSNFNLIVNEAPVSGEMDIRAAFRRTSLAGGGRRMTSAFLSTEGLEESGELNFSALLKKRDSFLRTANRGDGKSDSQPDVDVWEILRKAPPSEYEKIAFQYGITDLRGMLKRLKRIKKEEKKSTAFLKKLDPAYQVDKGQKIKLMVEVANPDADVKWLKNGQEIQVSGSKYIFEAIGNKRILTINHCSLADDAAYECVVAEEKSFTELFVKEPPILITHPLEDQMVMVGERVEFECEVSEEGATVKWEKDGVELTREETFKYRFKKDGKKQYLIINESTKEDSGHYTVKTNGGVSVAELIVQEKKLEVYQSIADLTVKARDQAVFKCEVSDENVKGIWLKNGKEVVPDERIKISHIGRIHKLTIEDVTPGDEADYSFIPQGFAYNLSAKLQFLEVKIDFVPREEPPKIHLDCLGQSPDTIVVVAGNKLRLDVPISGDPTPTVIWQKVNKKGELVHQSNEDSLTPSENSSDLSTDSKLLFESEGRVRVEKHEDHCVFIIEGAEKEDEGVYRVIVKNPVGEDKADITVKVIDVPDPPEAPKISNIGEDYCTVQWQPPTYDGGQPVLGYILERKKKKSYRWMRLNFDLLKELTYEAKRMIEGVVYEMRIYAVNSIGMSRPSPASQPFMPIAPPSEPTHFTVEDVSDTTVALKWRPPERIGAGGLDGYIVEYCKDGSAEWTPALPGLTERTSALIKDLVTGDKLYFRVKAINLAGESGAAIIKEPVTVQEIMQRPKIWLPRHLRQTLVKKVGETINIMIPFQGKPRPKISWMKDGQTLDSKDVGIRNSSTDTILFIRKAELHHSGAYEVTLQIENMTDTVAITIQIIDKPGPPQNIKLADVWGFNVALEWTPPQDDGNAQILGYTVQKADKKTMEWYTVYDHYRRTNCVVSDLIMGNEYFFRVFSENLCGLSETAATTKNPAYIQKTGTTYKPPSYKEHDFSEPPKFTHPLVNRSVIAGYNTTLSCAVRGIPKPKIFWYKNKVDLSGDAKYRMFSKQGVLTLEIRKPTPFDGGFYTCKAVNERGEAEIECRLDVRVPQ", "length": 1272, "header": "tr|A0A8V0ZVZ0-1|A0A8V0ZQB8_CHICK Computationally mapped isoform of Myosin-binding protein C, cardiac-type OS=Gallus gallus OX=9031 GN=MYBPC3 PE=3 SV=1 CANONICAL=A0A8V0ZQB8-1" }, "locus": { "chromosome": "5", "start_pos": 22569385, "end_pos": 22513533, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054663.1", "url": "https://www.ensembl.org/id/ENSGALT00010054663.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033023.1", "url": "https://www.ensembl.org/id/ENSGALP00010033023.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 695, "start_aa": "Thr", "end_pos": 695, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr695", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-390522", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-390522", "resource": "Reactome", "description": "Striated Muscle Contraction" } ], "orthologs": [ { "uniprot_canonical_ac": "P56741-1", "protein_name": "Myosin-binding protein C, cardiac-type", "gene_name": "Mybpc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEPGKRPVSAFTKKPRSVEVTAGSAAVFEAETERSGLKVQWQRDGSDIAANDKYGLAAEGKRHTLTVRDVGPDDQGSYAVIAGSSKVKFDLKVTEPAPPEKAESAVAPTSMEAPETPKEVPALATQLEGNVSSPEGSVSVTQDGSVAGSQGAPDDPIGLFLMRPQDGEVTVGGSIVFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQATSAGGYRCEVSTKDKFDSCNFNLTVHEAIGSGDLDLRSAFRRTSLAGTGRRTSDSHEDAGTLDFSSLLKKSSFRRDSKLEAPAEEDVWEILRQAPPSEYERIAFQHGVTDLRGMLKRLKGMKHDEKKSTAFQKKLEPAYQVNKGHKIRLTVELADPDAEVKWLKNGQEIQMSGRYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRSLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGRKHHLIINEATLEDAGHYAVRTSGGQALAELIVQEKKLEVYQSIADLAVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDNRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGSTPDTIVVVAGNKLRLDVPISGDPAPTVIWQKTITQGKKASAGPPPGAPEDAGADEEWVFDKKLLCETEGRVRVETTKDRSVFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCIVQWEPPAYDGGQPVLGYILERKKKKSYRWMRLNFDLLRELSHEARRMIEGVAYEMRVYAVNAVGMSRPSPASQPFMPIGPPGEPTHLTVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCQEGCSEWVTALQGLTERTSLLVKDLPTGARLLFRVRAHNVAGPGGPIITKEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAAHRTHSGTYQVTVRIENMEDKATLVLQIVDKPSPPLDIRVVETWGFSVALEWKPPQDDGNTEIWGYTVQKADKKTMEWFTVLEHYRQTHCVVSELIIGNGYYFRVFSHNMVGSSDRAAATKEPIFIPRPGITYEPPKYKALDFSEAPSFTQPLTNRSIIAGYNAILCCAVRGSPKPKISWFKNGLDLGEDARFRMFCKQGVLTLEIRKPCPYDGGVYVCRATNLQGEAQCECRLEVRVPQ", "length": 1274 }, "evidence": [ { "id": "A0A8V0ZQB8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQB8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14896-1", "protein_name": "Myosin-binding protein C, cardiac-type", "gene_name": "MYBPC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPEPGKKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRHTLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGESAPSPKGSSSAALNGPTPGAPDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTGDLDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTIVVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRVPQ", "length": 1274 }, "evidence": [ { "id": "A0A8V0ZQB8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQB8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "pmid": "" }, { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "pmid": "" }, { "name": "myosin heavy chain binding", "id": "GO:0032036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032036", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "pmid": "" }, { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "pmid": "" }, { "name": "ventricular cardiac muscle tissue morphogenesis", "id": "GO:0055010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "myosin filament", "id": "GO:0032982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "pmid": "" }, { "name": "cardiac myofibril", "id": "GO:0097512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "pmid": "" }, { "name": "striated muscle myosin thick filament", "id": "GO:0005863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005863", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1039, "end_pos": 1041, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1205, "end_pos": 1207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1213, "end_pos": 1215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 532, "end_pos": 534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 641, "end_pos": 643, "annotation": "n_glycosylation_sequon" }, { "start_pos": 723, "end_pos": 725, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": 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"synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 695 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1039, "end_pos": 1041 }, { "start_pos": 1067, "end_pos": 1069 }, { "start_pos": 1205, "end_pos": 1207 }, { "start_pos": 1213, "end_pos": 1215 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 309, "end_pos": 311 }, { "start_pos": 532, "end_pos": 534 }, { "start_pos": 641, "end_pos": 643 }, { "start_pos": 723, "end_pos": 725 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQB3-1", "uniprot_ac": "A0A8V0ZQB3", "uniprot_id": "A0A8V0ZQB3_CHICK", "mass": { "chemical_mass": 47039.0, "monoisotopic_mass": 47039.0 }, "refseq": { "ac": "XP_015134514", "name": "proline-serine-threonine phosphatase-interacting protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134514" }, "gene_names": [ { "name": "PSTPIP1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ] }, { "name": "PSTPIP1", "type": "synonym", "evidence": [ { "id": "XP_015134514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134514" } ] } ], "protein_names": [ { "name": "Proline-serine-threonine phosphatase-interacting protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3/entry#names_and_taxonomy" } ] }, { "name": "proline-serine-threonine phosphatase-interacting protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015134514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134514" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015134514.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015134514", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134514" } ] }, { "annotation": "Involved in regulation of the actin cytoskeleton. May regulate WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS and allow PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymerization required for synapse induction during T-cell activation. Down-regulates CD2-stimulated adhesion through the coupling of PTPN12 to CD2. Also has a role in innate immunity and the inflammatory response. Recruited to inflammasomes by MEFV. Induces formation of pyroptosomes, large supramolecular structures composed of oligomerized PYCARD dimers which form prior to inflammatory apoptosis. Binding to MEFV allows MEFV to bind to PYCARD and facilitates pyroptosome formation. Regulates endocytosis and cell migration in neutrophils.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3#function" }, { "database": "UniProtKB", "id": "ARBA00057396", "url": "https://www.uniprot.org/uniprotkb/ARBA00057396#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PSTPIP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3", "locus": { "chromosome": "10", "start_pos": 3166139, "end_pos": 3212837, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024045", "url": "https://www.ensembl.org/id/ENSGALG00010024045" } ] } } ], "crossref": [ { "id": "A0A8V0ZQB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000002786", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000002786", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11824", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11824", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415349", "url": "https://www.ncbi.nlm.nih.gov/gene/415349", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415349", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415349", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQB3", "url": "https://www.orthodb.org/?gene=A0A8V0ZQB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1N8H4", "url": "https://www.orthodb.org/?gene=F1N8H4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-844456", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-844456", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015134514", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015134514", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N8H4", "url": "https://www.uniprot.org/uniprotkb/F1N8H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1N8H4-1", "url": "https://www.uniprot.org/uniprotkb/F1N8H4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTQMQFKDAFWCKEFTLHTGFEVLVQRLLDGRKMCKDVEDLLKQRAQAEERYGKELVQIARKAGGQTEVNTLKAAFEKLKQQIESVGNSHIQLAGMLKDELKGIEEFRERQKEQRKKYEAAMERMQKSKLSHYKKTMESKKSYEQKCKEADEAEQSFERMSASGNQKQTEKSQNKAKQCRDAAHEAENVYKQNIEQLDKARTEWEEAHIKTCEVFQLQECDRITILRNSLWVHCNQLSMQCVKDDEQYEEVRVSLENCVVESDIDYFIKSKMTGTQPPGAIGYENYYDREPNRSNSPTQTCGMMKRFSGLLHGSSKNNAESVIPSAPPFEKTDGVYASIYVNEHERTSSSQDYRVLYDYTAQNMDELDINEGDIVAVIEENVDGWWTVERNGQRGFVPGSYLEKIC", "length": 406, "header": "tr|A0A8V0ZQB3-1|A0A8V0ZQB3_CHICK Isoform 1 of Proline-serine-threonine phosphatase-interacting protein 1 OS=Gallus gallus OX=9031 GN=PSTPIP1 PE=4 SV=1 CANONICAL=A0A8V0ZQB3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3/entry#A0A8V0ZQB3-1", "sequence": { "sequence": "MTQMQFKDAFWCKEFTLHTGFEVLVQRLLDGRKMCKDVEDLLKQRAQAEERYGKELVQIARKAGGQTEVNTLKAAFEKLKQQIESVGNSHIQLAGMLKDELKGIEEFRERQKEQRKKYEAAMERMQKSKLSHYKKTMESKKSYEQKCKEADEAEQSFERMSASGNQKQTEKSQNKAKQCRDAAHEAENVYKQNIEQLDKARTEWEEAHIKTCEVFQLQECDRITILRNSLWVHCNQLSMQCVKDDEQYEEVRVSLENCVVESDIDYFIKSKMTGTQPPGAIGYENYYDREPNRSNSPTQTCGMMKRFSGLLHGSSKNNAESVIPSAPPFEKTDGVYASIYVNEHERTSSSQDYRVLYDYTAQNMDELDINEGDIVAVIEENVDGWWTVERNGQRGFVPGSYLEKIC", "length": 406, "header": "tr|A0A8V0ZQB3-1|A0A8V0ZQB3_CHICK Isoform 1 of Proline-serine-threonine phosphatase-interacting protein 1 OS=Gallus gallus OX=9031 GN=PSTPIP1 PE=4 SV=1 CANONICAL=A0A8V0ZQB3-1" }, "locus": { "chromosome": "10", "start_pos": 3212523, "end_pos": 3167855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058586.1", "url": "https://www.ensembl.org/id/ENSGALT00010058586.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035612.1", "url": "https://www.ensembl.org/id/ENSGALP00010035612.1" } ] } }, { "isoform_ac": "F1N8H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3/entry#F1N8H4-1", "sequence": { "sequence": "MTQMQFKDAFWCKEFTLHTGFEVLVQRLLDGRKMCKDVEDLLKQRAQAEERYGKELVQIARKAGGQTEVNTLKAAFEKLKQQIESVGNSHIQLAGMLKDELKGIEEFRERQKEQRKKYEAAMERMQKSKLSHYKKTMESQNKAKQCRDAAHEAENVYKQNIEQLDKARTEWEEAHIKTCEVFQLQECDRITILRNSLWVHCNQLSMQCVKDDEQYEEVRVSLENCVVESDIDYFIKSKMTGTQPPGAIGYENYYDREPNRSNSPTQTCGMMKRFSGLLHGSSKNNAESVIPSAPPFEKTDGVYASIYVNEHERTSSSQDYRVLYDYTAQNMDELDINEGDIVAVIEENVDGWWTVERNGQRGFVPGSYLEKIC", "length": 373, "header": "tr|F1N8H4-1|A0A8V0ZQB3_CHICK Computationally mapped isoform of Proline-serine-threonine phosphatase-interacting protein 1 OS=Gallus gallus OX=9031 GN=PSTPIP1 PE=4 SV=5 CANONICAL=A0A8V0ZQB3-1" }, "locus": { "chromosome": "10", "start_pos": 3212523, "end_pos": 3167855, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058581.1", "url": "https://www.ensembl.org/id/ENSGALT00010058581.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035608.1", "url": "https://www.ensembl.org/id/ENSGALP00010035608.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415349", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415349", "resource": "KEGG Pathway" }, { "id": "R-GGA-844456", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-844456", "resource": "Reactome", "description": "The NLRP3 inflammasome" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" }, { "name": "uropod", "id": "GO:0001931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001931", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" }, { "id": "PS51741", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51741" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-BAR", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 263, "start_aa": "Met", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB3" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 348, "end_pos": 406, "start_aa": "Ser", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 292, "end_pos": 294 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQB6-1", "uniprot_ac": "A0A8V0ZQB6", "uniprot_id": "A0A8V0ZQB6_CHICK", "mass": { "chemical_mass": 49184.0, "monoisotopic_mass": 49184.0 }, "refseq": { "ac": "NP_001136143", "name": "dopamine D1C receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001136143" }, "gene_names": [ { "name": "DD1CR", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6" } ] }, { "name": "DD1CR", "type": "synonym", "evidence": [ { "id": "NP_001136143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001136143" } ] } ], "protein_names": [ { "name": "Dopamine D1C receptor", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6/entry#names_and_taxonomy" } ] }, { "name": "dopamine D1C receptor", "type": "synonym", "evidence": [ { "id": "NP_001136143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001136143" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript is intronless :: FJ432666.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000232.1. On Nov 27, 2021 this sequence version replaced NP_001136143.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001136143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001136143" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DD1CR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZQB6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQB6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15057", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15057", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "428961", "url": "https://www.ncbi.nlm.nih.gov/gene/428961", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428961", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428961", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FCNIWIS", "url": "https://omabrowser.org/oma/group/FCNIWIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQB6", "url": "https://www.orthodb.org/?gene=A0A8V0ZQB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248:SF193", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248:SF193", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001136143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001136143", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASTAGGPRALRALTGCLLGALVLGTLAGNALVCLAVLRFRHLRTKVTNWFVLSLAISDLCVAILVMPWKAVTEVAGGFWLFGSRFCDTWVAFDIMCSTASILHLCIISLDRYWAIASPFRYERRMTQRLACAMIAMAWALSILISFVPVQLHWHKAKDRRHPSSSCDVSLNHTYAITSSLISFYIPVAIMIVTYTRIYRIAQAQIRRISTLERAGGQWPAHSKEPASTLRSSLRKETKVLQTLSIIMGVFVCCWLPFFLLNCLLPFCQPESDSNGQSPCIGQTTFNVFVWFGWANSSVNPVIYAFNADFRRAFSNLLGCQSLCCSTPRAAVERVNLSNELVSYHQDTTCQKDGATAAIPPTTVTAWVQPEPHAVSPQQEDREELPTEERPVTAPTQAMLGSSPKCCHVTATLQLDCGADLSLETINAFTGFSRHEGHHHPIPEG", "length": 445, "header": "tr|A0A8V0ZQB6-1|A0A8V0ZQB6_CHICK Isoform 1 of Dopamine D1C receptor OS=Gallus gallus OX=9031 GN=DD1CR PE=3 SV=1 CANONICAL=A0A8V0ZQB6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6/entry#A0A8V0ZQB6-1", "sequence": { "sequence": "MASTAGGPRALRALTGCLLGALVLGTLAGNALVCLAVLRFRHLRTKVTNWFVLSLAISDLCVAILVMPWKAVTEVAGGFWLFGSRFCDTWVAFDIMCSTASILHLCIISLDRYWAIASPFRYERRMTQRLACAMIAMAWALSILISFVPVQLHWHKAKDRRHPSSSCDVSLNHTYAITSSLISFYIPVAIMIVTYTRIYRIAQAQIRRISTLERAGGQWPAHSKEPASTLRSSLRKETKVLQTLSIIMGVFVCCWLPFFLLNCLLPFCQPESDSNGQSPCIGQTTFNVFVWFGWANSSVNPVIYAFNADFRRAFSNLLGCQSLCCSTPRAAVERVNLSNELVSYHQDTTCQKDGATAAIPPTTVTAWVQPEPHAVSPQQEDREELPTEERPVTAPTQAMLGSSPKCCHVTATLQLDCGADLSLETINAFTGFSRHEGHHHPIPEG", "length": 445, "header": "tr|A0A8V0ZQB6-1|A0A8V0ZQB6_CHICK Isoform 1 of Dopamine D1C receptor OS=Gallus gallus OX=9031 GN=DD1CR PE=3 SV=1 CANONICAL=A0A8V0ZQB6-1" }, "locus": { "chromosome": "6", "start_pos": 20842551, "end_pos": 20841217, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055560.1", "url": "https://www.ensembl.org/id/ENSGALT00010055560.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033666.1", "url": "https://www.ensembl.org/id/ENSGALP00010033666.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428961", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428961", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of MAPK cascade", "id": "GO:0043410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6" } ], "pmid": "" }, { "name": "adenylate cyclase-activating adrenergic receptor signaling pathway", "id": "GO:0071880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQB6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 304, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 336, "end_pos": 338 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQF3-1", "uniprot_ac": "A0A8V0ZQF3", "uniprot_id": "A0A8V0ZQF3_CHICK", "mass": { "chemical_mass": 89830.0, "monoisotopic_mass": 89830.0 }, "refseq": { "ac": "XP_425694", "name": "EMILIN-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425694" }, "gene_names": [ { "name": "EMILIN3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF3" } ] }, { "name": "EMILIN3", "type": "synonym", "evidence": [ { "id": "XP_425694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425694" } ] } ], "protein_names": [ { "name": "EMILIN-3", "type": "synonym", "evidence": [ { "id": "XP_425694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425694" } ] }, { "name": "Elastin microfibril interfacer 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_425694.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_425694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425694" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EMILIN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF3", "locus": { "chromosome": "20", "start_pos": 5314522, "end_pos": 5322664, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022392", "url": "https://www.ensembl.org/id/ENSGALG00010022392" } ] } } ], "crossref": [ { "id": "A0A8V0ZQF3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQF3", "database": "AlphaFoldDB", "categories": [] }, { "id": "428137", "url": "https://www.ncbi.nlm.nih.gov/gene/428137", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428137", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428137", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EDCQNKN", "url": "https://omabrowser.org/oma/group/EDCQNKN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQF3", "url": "https://www.orthodb.org/?gene=A0A8V0ZQF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2129379", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2129379", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_425694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_425694", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRALRRGALLACFSLGTLLALADAKGTFYPPAAPLPYGGRYNLYTTGSSPQLGKPVGKHKSYCAYVVQRNVTCVLQDGAESYVKAEYHKCSWGPKCPGKVLYRTFFRPRYKIGYKTVTELAWRCCPGFMGEGCHDSPTDQPGLMPQHPGPKMPPGPKMFPLPRVPPHPKSHPDLFAGPKKNQYGRKLPGLVGDRLERLEEEVRRLAQAYDSLHVLVSGLGDRLRLAIQEDTTKMIGSLMNSPGTPDSSVGFGIIPDGLVDVADKADVASYPPVGEILTKVAEVSDVLKSKADLLHEVRGMVLEHDGQLKHLLEAARPSPLTSMELLEEYVAARLGSLRGELLDGFEKQLGKIQTACDFRIQEVQQQCEQEKAANLRLQQTLDGKELEIKKEISQLETQIQGLTVVESCCSSLDYLTDRMNILEKGLHSISESQKNLHSRMDGEISAVTLGNLFEGRFEDLEARMNATERETGSCCSSMEDSMRGTVVAEVDGMRTAFEDKMQTLEDRFMSIVGELNNVSAPVGMDGAVVPVLEGELASMRKRTDEKLEVLQNRLVTLESTCSSGCSSASKDVETFRTEIEDCQNKNQDLLLRMDSTSELLRKLNATILEIQRRIEEEAAGALQGEITLLKINLSTVSKSLTGLKDSVSQYSDTMTHVNSSLDEHERKIEDEVRSIQERVGDHGSQLFFSNRRVLNLKGDLERLKARIAAELSSCRSAARSLQRDVAHFDERVARVEGACGRLGAVLGSLDGVRGELDRHAGGLWDRMDRLNGTLAAHSQEITGLKDNLLDCQAKVLELAEQLGHLEERAAGKH", "length": 814, "header": "tr|A0A8V0ZQF3-1|A0A8V0ZQF3_CHICK Isoform 1 of Elastin microfibril interfacer 3 OS=Gallus gallus OX=9031 GN=EMILIN3 PE=1 SV=1 CANONICAL=A0A8V0ZQF3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF3/entry#A0A8V0ZQF3-1", "sequence": { "sequence": "MRRALRRGALLACFSLGTLLALADAKGTFYPPAAPLPYGGRYNLYTTGSSPQLGKPVGKHKSYCAYVVQRNVTCVLQDGAESYVKAEYHKCSWGPKCPGKVLYRTFFRPRYKIGYKTVTELAWRCCPGFMGEGCHDSPTDQPGLMPQHPGPKMPPGPKMFPLPRVPPHPKSHPDLFAGPKKNQYGRKLPGLVGDRLERLEEEVRRLAQAYDSLHVLVSGLGDRLRLAIQEDTTKMIGSLMNSPGTPDSSVGFGIIPDGLVDVADKADVASYPPVGEILTKVAEVSDVLKSKADLLHEVRGMVLEHDGQLKHLLEAARPSPLTSMELLEEYVAARLGSLRGELLDGFEKQLGKIQTACDFRIQEVQQQCEQEKAANLRLQQTLDGKELEIKKEISQLETQIQGLTVVESCCSSLDYLTDRMNILEKGLHSISESQKNLHSRMDGEISAVTLGNLFEGRFEDLEARMNATERETGSCCSSMEDSMRGTVVAEVDGMRTAFEDKMQTLEDRFMSIVGELNNVSAPVGMDGAVVPVLEGELASMRKRTDEKLEVLQNRLVTLESTCSSGCSSASKDVETFRTEIEDCQNKNQDLLLRMDSTSELLRKLNATILEIQRRIEEEAAGALQGEITLLKINLSTVSKSLTGLKDSVSQYSDTMTHVNSSLDEHERKIEDEVRSIQERVGDHGSQLFFSNRRVLNLKGDLERLKARIAAELSSCRSAARSLQRDVAHFDERVARVEGACGRLGAVLGSLDGVRGELDRHAGGLWDRMDRLNGTLAAHSQEITGLKDNLLDCQAKVLELAEQLGHLEERAAGKH", "length": 814, "header": "tr|A0A8V0ZQF3-1|A0A8V0ZQF3_CHICK Isoform 1 of Elastin microfibril interfacer 3 OS=Gallus gallus OX=9031 GN=EMILIN3 PE=1 SV=1 CANONICAL=A0A8V0ZQF3-1" }, "locus": { "chromosome": "20", "start_pos": 5322652, "end_pos": 5316881, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054441.1", "url": "https://www.ensembl.org/id/ENSGALT00010054441.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032885.1", "url": "https://www.ensembl.org/id/ENSGALP00010032885.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428137", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428137", "resource": "KEGG Pathway" }, { "id": "R-GGA-2129379", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2129379", "resource": "Reactome", "description": "Molecules associated with elastic fibres" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQ65-1", "protein_name": "Elastin microfibril interfacer 3", "gene_name": "Emilin3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ARGRAAAGTRGGLRRGAPPLPPAGTRAEASRPGCPSHRRGGSPDTILCAGRRPAIQEAAGLAKNKSVKGAWRGGWDPGSARGNLSSEVTFSSCAVSKLQAQRTRWRERRKGCPRLEHAGLPQANAFCLSSALRGCRQSHAYRRSLCAYVVHRNVTCVLQEGAESFVKAEYRNCGWGPNCPSTVRYRTVFRPRYKIGYKAVTDLAWRCCPGLTGEGCPEHLEDHGATPPHQEPEPQIPLGQLGPGPRPSPYSREAPHPRGFGVIPEGLADPEGRGRGPRIPPLSEILSKVTEVSNTLQTKVQLLDEVRGLALGHEAHLQRLREAPPSPLTSLALLEEYVDQRLQRLWGSLLDGFEQKLQGVQSECDLRVQEVRQQCEEGQAASQRLHQSLDGRELALRRELSQLGTQLQGLTLTGGGTCCSQLALISARVDSLERNLQAVTETQGGPSTLAADELARLSAAMLQGGVDGLLEGLETINRTENGARGCCLRMEMGGWGVGGFGSTLEERVQSLEERLATLTGELKPKGAIPDRSVRPLVHSELAVLEQRLVSLETSCTPSTTTAILDNLVAEVKAWQSRSEALLHQVARHTALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERRVEAEVHAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVANVAGGLSRCRDTAQELQHTVSHFDQRVAQVEGAYERLGLLAAHLNSLPTEQLRSREGLWGHIDKLNHTLAQHTQDIARLRDDLLDCRAQLAEVRPGRAD", "length": 799 }, "evidence": [ { "id": "A0A8V0ZQF3", "url": "https://omabrowser.org/oma/group/A0A8V0ZQF3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P59900-1", "protein_name": "EMILIN-3", "gene_name": "Emilin3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRRLSVWLCTVAALLSGAQAKGTPLLARPAQPSASRYSLYTTGWRPRLRPGPHKSLCAYVVHRNVTCVLQEGAESYIKAEYRNCGWGPNCPSTVRYRTVFRPRYKIGYKTVTDLAWRCCPGLTGESCPEHLTDHGATPPHQEPEPQIPLGQLGPGPRPSPYSREAPRPRGRKGQGPFGERLEQRLSQAYGTLSGLVASHENPNRITGDSRAPVVPIGFGVIPEGLVAPEDRGRGPLIPPLSEILSKVTEVSNTLQTKVQLLDEVRGLALGHEAHLQRLREAPPSPLTSLALLEEYVDQRLQRLWGSLLDGFEQKLQGVQSECDLRVQEVRQQCEEGQAASQRLHQSLDGRELALRRELSQLGTQLQGLTLTGGGTCCSQLALISARVDSLERNLQAVTETQGGPGTLAADELARLSAAMLQGGVDGLLEGLETINGTENGARGCCLRMEVGGWGVGGFGSTLEQRVQSLEERLATLTGELSPESAIPDRSARPLVHSELAVLEQRLVSLETSCTPSTTTAILDNLVAEVKAWQSRSEALLHQVARHTALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFSAANTSLDERERRVEAEVHTIQEQISSQGSRLQAGHRQVLNLRGELEQLKAGMANVARGLSRCRDTAQELQHTVGHFDQRVAQVEGACERLGLLATHLNSLPTEQLRSREGLWGHIDKLNHTLAQHTQDIARLRDDLLDCRAQLAEVRPGRAD", "length": 758 }, "evidence": [ { "id": "A0A8V0ZQF3", "url": "https://omabrowser.org/oma/group/A0A8V0ZQF3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NT22-1", "protein_name": "EMILIN-3", "gene_name": "EMILIN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRRRLLVWLCAVAALLSGAQARGTPLLARPAPPGASRYSLYTTGWRPRLRPGPHKALCAYVVHRNVTCILQEGAESYVKAEYRQCRWGPKCPGTVTYRTVLRPKYKVGYKTVTDLAWRCCPGFTGKRCPEHLTDHGAASPQLEPEPQIPSGQLDPGPRPPSYSRAAPSPHGRKGPGLFGERLERLEGDVQRLAQTYGTLSGLVASHEDPNRMTGGPRAPAVPVGFGVIPEGLVGPGDRARGPLTPPLDEILSKVTEVSNTLQTKVQLLDKVHGLALGHEAHLQRLREAPPSPLTSLALLEEYVDRRLHRLWGSLLDGFEQKLQGVQSECDLRVQEVRRQCEEGQAASRRLHQSLDGRELALRQELSQLGSQLQGLSVSGRGSCCGQLALINARMDGLERALQAVTETQRGPGAPAGDELTRLSAAMLEGGVDGLLEGLETLNGTEGGARGCCLRLDMGGWGVGGFGTMLEERVQSLEERLATLAGELSHDSASPGRSARPLVQTELAVLEQRLVSLETSCTPSTTSAILDSLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAKVASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPLRPREGLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQLAEQVRPGQAN", "length": 766 }, "evidence": [ { "id": "A0A8V0ZQF3", "url": "https://omabrowser.org/oma/group/A0A8V0ZQF3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQF3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"gene_names": [ { "name": "EFCAB14", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF6" } ] } ], "protein_names": [ { "name": "EF-hand calcium binding domain 14", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EFCAB14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF6", "locus": { "chromosome": "8", "start_pos": 21545441, "end_pos": 21558399, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022874", "url": "https://www.ensembl.org/id/ENSGALG00010022874" } ] } } ], "crossref": [ { "id": "A0A8V0ZQF6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQF6", "url": "https://www.orthodb.org/?gene=A0A8V0ZQF6", "database": "OrthoDB", "categories": [ "Protein Classification" 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"MARAGAAAPPPPTPHKRMKKRKELNALIGLAADGRRKKPAKKGSGHRLLRTEPPASDSESSSEEDEFAAAGGRGRCAKGDYLRCCKFCYPLCAFVILAACVVACVGLVWMQVALKEDLDVIKEKFRTMESNQKTSFQEIPKLNEDLVQQQKQLEQIETGELGLNKVWINITEINKQISLLTSTVNHLKTNVKSASDLISLPVTVEKLQKTVATIGSTLTSVSHDVENIQTAIEEYKKSLEILQNDVKELKHSTALPMTEKNQTENCKQESQALHAALEELNNTIVTNQKLNDIKLLNVDSAIGNLSQRVMLLENTPVAVNKLEKRNNLSTSPGNDTTTSAKVENEDQPVNETHSNKKPKEAGTRDSQELNLREKLQLLTARASRLEDDRPIETSKNVESSPSTMTKPTDLSRLASRSADDSTEKNRQLRHLSLPGISSIEDLQDLFDKAPEDADGKLSFEDLQKLLGSAAQDSQIFKKFDTDGDEKYSLEELRLALGV", "length": 498, "header": "tr|A0A8V0ZQF6-1|A0A8V0ZQF6_CHICK Isoform 1 of EF-hand calcium binding domain 14 OS=Gallus gallus OX=9031 GN=EFCAB14 PE=4 SV=1 CANONICAL=A0A8V0ZQF6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF6/entry#A0A8V0ZQF6-1", "sequence": { "sequence": 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"https://www.ensembl.org/id/ENSGALP00010033711.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 13, "start_aa": "Thr", "end_pos": 13, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr13", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQF6" }, { "id": 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"table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQG5-1", "uniprot_ac": "A0A8V0ZQG5", "uniprot_id": "A0A8V0ZQG5_CHICK", "mass": { "chemical_mass": 39075.0, "monoisotopic_mass": 39075.0 }, "refseq": { "ac": "XP_001231870", "name": "uracil nucleotide/cysteinyl leukotriene receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231870" }, "gene_names": [ { "name": "GPR17", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5" } ] }, { "name": "GPR17", "type": "synonym", "evidence": [ { "id": "XP_001231870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231870" } ] } ], "protein_names": [ { "name": "Uracil nucleotide/cysteinyl leukotriene receptor", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 17", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5/entry#names_and_taxonomy" } ] }, { "name": "uracil nucleotide/cysteinyl leukotriene receptor", "type": "synonym", "evidence": [ { "id": "XP_001231870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231870" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001231870.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001231870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231870" } ] }, { "annotation": "Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5#function" }, { "database": "UniProtKB", "id": "ARBA00059735", "url": "https://www.uniprot.org/uniprotkb/ARBA00059735#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPR17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5", "locus": { "chromosome": "9", "start_pos": 1021614, "end_pos": 1006344, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024064", "url": "https://www.ensembl.org/id/ENSGALG00010024064" } ] } } ], "crossref": [ { "id": "cd15161", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15161", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769024", "url": "https://www.ncbi.nlm.nih.gov/gene/769024", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769024", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769024", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TCLNGAM", "url": "https://omabrowser.org/oma/group/TCLNGAM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQG5", "url": "https://www.orthodb.org/?gene=A0A8V0ZQG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-391906", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-391906", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-417957", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-417957", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001231870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001231870", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGPADPSSLLFNCSNQSNFPFEASEQCGKETHLENVLFATFYFLDFILAFIGNSLALWLFVRDQKSGTPANIFLMHLAVADLSFVLVLPTRLVYHFSGNHWPFGEIPCRLTGFLFYLNMYASIYFLMCISVDRFLAIVHPVKSIKLRRPLYAHLACAFLWLIVGVAMAPLLLSVQTVEVNNTTICLQLYREKASRHALVSLAVAFTFPFVTTVTCYLLIIRSLKSGNRVEKHLKEKAIKMIIMVLMIFLVCFVPYHVNRYIYILHYNGTKASCETQRLLALNNRITSCLTSLNGAFDPVMYFFVAEKFREALCNLFCGRRPVMTLQTCEGKTNESSLSAKSEL", "length": 344, "header": "tr|A0A8V0ZQG5-1|A0A8V0ZQG5_CHICK Isoform 1 of Uracil nucleotide/cysteinyl leukotriene receptor OS=Gallus gallus OX=9031 GN=GPR17 PE=3 SV=1 CANONICAL=A0A8V0ZQG5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5/entry#A0A8V0ZQG5-1", "sequence": { "sequence": "MKGPADPSSLLFNCSNQSNFPFEASEQCGKETHLENVLFATFYFLDFILAFIGNSLALWLFVRDQKSGTPANIFLMHLAVADLSFVLVLPTRLVYHFSGNHWPFGEIPCRLTGFLFYLNMYASIYFLMCISVDRFLAIVHPVKSIKLRRPLYAHLACAFLWLIVGVAMAPLLLSVQTVEVNNTTICLQLYREKASRHALVSLAVAFTFPFVTTVTCYLLIIRSLKSGNRVEKHLKEKAIKMIIMVLMIFLVCFVPYHVNRYIYILHYNGTKASCETQRLLALNNRITSCLTSLNGAFDPVMYFFVAEKFREALCNLFCGRRPVMTLQTCEGKTNESSLSAKSEL", "length": 344, "header": "tr|A0A8V0ZQG5-1|A0A8V0ZQG5_CHICK Isoform 1 of Uracil nucleotide/cysteinyl leukotriene receptor OS=Gallus gallus OX=9031 GN=GPR17 PE=3 SV=1 CANONICAL=A0A8V0ZQG5-1" }, "locus": { "chromosome": "9", "start_pos": 1011621, "end_pos": 1010590, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058655.1", "url": "https://www.ensembl.org/id/ENSGALT00010058655.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035664.1", "url": "https://www.ensembl.org/id/ENSGALP00010035664.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769024", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769024", "resource": "KEGG Pathway" }, { "id": "R-GGA-391906", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-391906", "resource": "Reactome", "description": "Leukotriene receptors" }, { "id": "R-GGA-416476", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-416476", "resource": "Reactome", "description": "G alpha (q) signalling events" }, { "id": "R-GGA-417957", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-417957", "resource": "Reactome", "description": "P2Y receptors" }, { "id": "R-GGA-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BHH2-1", "protein_name": "Uracil nucleotide/cysteinyl leukotriene receptor", "gene_name": "GPR17", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNGLEAASPDLTANTSLVSTEQCGQETPLENILFASFYLLDFILAFGGNALALWLFVRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIPCRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLHAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVICLQLYREKASQHALASLAVAFTFPFVTTVTCYLLIIRSLRQGPRVERRLKNKAVRMIAAVLAIFLVCFVPYHVHRSVYVLRYHGHHTSCAAQRILALGNRITSCLTSLNGALDPVMYFFVAEKFRDALCNLLCGKRLPGPPPSGDGKTNESSLSARSEL", "length": 339 }, "evidence": [ { "id": "A0A8V0ZQG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZQG5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q09QM4-1", "protein_name": "Uracil nucleotide/cysteinyl leukotriene receptor", "gene_name": "Gpr17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGLETALPSLTDNASLAYSEQCGQETPLENMLFACFYLLDFILAFVGNALALWLFIWDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIPCRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWIVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALASLAVAFTFPFITTVTCYLLIIRSLRQGPRIEKHLKNKAVRMIAMVLAIFLICFVPYHIHRSVYVLHYRGGGTSCSAQRALALGNRITSCLTSLNGALDPVMYFFVAEKFRHALCNLLCSKRLTGPPPSFEGKTNESSLSARSEL", "length": 339 }, "evidence": [ { "id": "A0A8V0ZQG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZQG5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13304-1", "protein_name": "Uracil nucleotide/cysteinyl leukotriene receptor", "gene_name": "GPR17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESSLSAKSEL", "length": 367 }, "evidence": [ { "id": "A0A8V0ZQG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZQG5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NS65-1", "protein_name": "Uracil nucleotide/cysteinyl leukotriene receptor", "gene_name": "Gpr17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGLEAALPSLTDNSSLAYSEQCGQETPLENMLFACFYLLDFILAFVGNALALWLFIWDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIPCRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWIVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALASLAVAFTFPFITTVTCYLLIIRSLRQGPRIEKHLKNKAVRMIAMVLAIFLICFVPYHIHRSVYVLHYRGGGTSCAAQRALALGNRITSCLTSLNGALDPVMYFFVAEKFRHALCNLLCSKRLTGPPPSFEGKTNESSLSARSEL", "length": 339 }, "evidence": [ { "id": "A0A8V0ZQG5", "url": "https://omabrowser.org/oma/group/A0A8V0ZQG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQG5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQG5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 302, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 }, { "start_pos": 16, "end_pos": 18 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 334, "end_pos": 336 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQH3-1", "uniprot_ac": "A0A8V0ZQH3", "uniprot_id": "A0A8V0ZQH3_CHICK", "mass": { "chemical_mass": 68383.0, "monoisotopic_mass": 68383.0 }, "refseq": {}, "gene_names": [ { "name": "RUNDC1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH3" } ] } ], "protein_names": [ { "name": "RUN domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May play a role as p53/TP53 inhibitor and thus may have oncogenic activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH3#function" }, { "database": "UniProtKB", "id": "ARBA00055063", "url": "https://www.uniprot.org/uniprotkb/ARBA00055063#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RUNDC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH3", "locus": { "chromosome": "27", "start_pos": 5097549, "end_pos": 5093134, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022407", "url": "https://www.ensembl.org/id/ENSGALG00010022407" } ] } } ], "crossref": [ { "id": "A0A8V0ZQH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQH3", "url": "https://www.orthodb.org/?gene=A0A8V0ZQH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47194:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47194:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZQH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVPAPRRTTSDRRERGRALLLPLPPSLKGALWQIAAGGALWCRAGPAPPAPRREDGGGCAAQVAAIMESEGGPLGPGERWAPVGAVTVEQEEEEEEEETAGSPRSVPRLRAERRRLHGALLALASHFAQVQFRLRQVARAGPAEQQRLLRDLEDFAFRGCPAPLAHELGDGPSEQEKQEQIEIHKEKQRELILQLKTQLDDLETFAYQEGSYDSLPQSVVMERQRMIIDELIKKLDMNLSEDIATLSPEELRQRVDAAIAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSSGKAEDGHCECASRKDGGGSFKPNIWSSGNRVNPEDAKKMRETGLHLMRRMLAVLQIFAVSQFGCATGQIPRSLWQKDQTNKDYSPLIKKLELSVDRVRQLALKHQQDDHVISSSDLQDISLGGRDELTLAVRKELTIALRDLMAHGLCASSQGMSLVLAPIACLIPAFTSSPQTMHPWELFVEYYKTKNGQAFVESPARKLSQSFALPVSGGVTITPKQSLLTAVHTVLTEHNPFKRSADSELKALVCMALNEQRLVSWVNLICKSGALVQSHYHPWSYMVNTGFESALNILSRLSSLKFSLPVDLAVRQLKNIKDAF", "length": 616, "header": "tr|A0A8V0ZQH3-1|A0A8V0ZQH3_CHICK Isoform 1 of RUN domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RUNDC1 PE=1 SV=1 CANONICAL=A0A8V0ZQH3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH3/entry#A0A8V0ZQH3-1", "sequence": { "sequence": "MSVPAPRRTTSDRRERGRALLLPLPPSLKGALWQIAAGGALWCRAGPAPPAPRREDGGGCAAQVAAIMESEGGPLGPGERWAPVGAVTVEQEEEEEEEETAGSPRSVPRLRAERRRLHGALLALASHFAQVQFRLRQVARAGPAEQQRLLRDLEDFAFRGCPAPLAHELGDGPSEQEKQEQIEIHKEKQRELILQLKTQLDDLETFAYQEGSYDSLPQSVVMERQRMIIDELIKKLDMNLSEDIATLSPEELRQRVDAAIAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQDEVGSSGKAEDGHCECASRKDGGGSFKPNIWSSGNRVNPEDAKKMRETGLHLMRRMLAVLQIFAVSQFGCATGQIPRSLWQKDQTNKDYSPLIKKLELSVDRVRQLALKHQQDDHVISSSDLQDISLGGRDELTLAVRKELTIALRDLMAHGLCASSQGMSLVLAPIACLIPAFTSSPQTMHPWELFVEYYKTKNGQAFVESPARKLSQSFALPVSGGVTITPKQSLLTAVHTVLTEHNPFKRSADSELKALVCMALNEQRLVSWVNLICKSGALVQSHYHPWSYMVNTGFESALNILSRLSSLKFSLPVDLAVRQLKNIKDAF", "length": 616, "header": "tr|A0A8V0ZQH3-1|A0A8V0ZQH3_CHICK Isoform 1 of RUN domain-containing protein 1 OS=Gallus gallus OX=9031 GN=RUNDC1 PE=1 SV=1 CANONICAL=A0A8V0ZQH3-1" }, "locus": { "chromosome": "27", "start_pos": 5096545, "end_pos": 5093333, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054462.1", "url": "https://www.ensembl.org/id/ENSGALT00010054462.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032900.1", "url": "https://www.ensembl.org/id/ENSGALP00010032900.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQH3" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 424, "end_pos": 605, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 239, "end_pos": 241 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQI2-1", "uniprot_ac": "A0A8V0ZQI2", "uniprot_id": "A0A8V0ZQI2_CHICK", "mass": { "chemical_mass": 62000.0, "monoisotopic_mass": 62000.0 }, "refseq": {}, "gene_names": [ { "name": "SPATS2L", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2" } ] } ], "protein_names": [ { "name": "Spermatosis associated serine rich 2 like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SPATS2L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2", "locus": { "chromosome": "7", "start_pos": 10795687, "end_pos": 10651428, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024075", "url": "https://www.ensembl.org/id/ENSGALG00010024075" } ] } } ], "crossref": [ { "id": "A0A8V0ZQI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "424067", "url": "https://www.ncbi.nlm.nih.gov/gene/424067", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NPKMMSS", "url": "https://omabrowser.org/oma/group/NPKMMSS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQI2", "url": "https://www.orthodb.org/?gene=A0A8V0ZQI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQI9", "url": "https://www.orthodb.org/?gene=A0A8V0ZQI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVP8", "url": "https://www.orthodb.org/?gene=A0A8V0ZVP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVQ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZVQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVQ9", "url": "https://www.orthodb.org/?gene=A0A8V0ZVQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZXS9", "url": "https://www.orthodb.org/?gene=A0A8V0ZXS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZG1", "url": "https://www.orthodb.org/?gene=A0A8V0ZZG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15623", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15623", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15623:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15623:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07139", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07139", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZQI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQI9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZXS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZG1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEISSPVNIKEKINAIRSVVPNKSNNEIVLVLQQFDNNVDKAVQAFIDGKYSSATQVLKEWNMTGKKKNNRRKRSKSKQHQGNKDAKNKNDGPDKASQEPQRIHGCHLNGCSKDSRSGDSANEKLEATSLENRSSQFVASAPGCPETTGKEREHQRVSVELSPKTVNGVEQHEPLQSSVQFQGNLGRPKSKSSSVKSSNATSQLETKPDDSVKKRGPNIEKSVKDLQRCTVSLTRYRMMIKEEVDNSVKKIKAAFAELHSCIIDKEVSLMAEIDKVKEEAMEILTARQKKAEELKRLTDLASQMAEAQLSELRAEIKHFVSERKYDEELGRSARFSCDTEQLKTQIQLCGEISHPKNNYSSRTPCSSVLSSLTSHATTGKQNTHTRKSSSNAKNSDNKTASTKVQSHHSSNPTESSSQGIPTNKQNGPSSQRRRFNPQHQNVRLNGSLKPQGTTNEADQNNVKSGSRSEHRRQQHNNFRPKNKGAMKNQEQSATARTTENVTHPEKSRRKHHTADTTDHRPFRGGVGRVSQCNLCPARMEVSPDTTVLSVPAVTLVA", "length": 558, "header": "tr|A0A8V0ZQI2-1|A0A8V0ZQI2_CHICK Isoform 1 of Spermatosis associated serine rich 2 like OS=Gallus gallus OX=9031 GN=SPATS2L PE=1 SV=1 CANONICAL=A0A8V0ZQI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2/entry#A0A8V0ZQI2-1", "sequence": { "sequence": "MAEISSPVNIKEKINAIRSVVPNKSNNEIVLVLQQFDNNVDKAVQAFIDGKYSSATQVLKEWNMTGKKKNNRRKRSKSKQHQGNKDAKNKNDGPDKASQEPQRIHGCHLNGCSKDSRSGDSANEKLEATSLENRSSQFVASAPGCPETTGKEREHQRVSVELSPKTVNGVEQHEPLQSSVQFQGNLGRPKSKSSSVKSSNATSQLETKPDDSVKKRGPNIEKSVKDLQRCTVSLTRYRMMIKEEVDNSVKKIKAAFAELHSCIIDKEVSLMAEIDKVKEEAMEILTARQKKAEELKRLTDLASQMAEAQLSELRAEIKHFVSERKYDEELGRSARFSCDTEQLKTQIQLCGEISHPKNNYSSRTPCSSVLSSLTSHATTGKQNTHTRKSSSNAKNSDNKTASTKVQSHHSSNPTESSSQGIPTNKQNGPSSQRRRFNPQHQNVRLNGSLKPQGTTNEADQNNVKSGSRSEHRRQQHNNFRPKNKGAMKNQEQSATARTTENVTHPEKSRRKHHTADTTDHRPFRGGVGRVSQCNLCPARMEVSPDTTVLSVPAVTLVA", "length": 558, "header": "tr|A0A8V0ZQI2-1|A0A8V0ZQI2_CHICK Isoform 1 of Spermatosis associated serine rich 2 like OS=Gallus gallus OX=9031 GN=SPATS2L PE=1 SV=1 CANONICAL=A0A8V0ZQI2-1" }, "locus": { "chromosome": "7", "start_pos": 10784522, "end_pos": 10747632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058702.1", "url": "https://www.ensembl.org/id/ENSGALT00010058702.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035689.1", "url": "https://www.ensembl.org/id/ENSGALP00010035689.1" } ] } }, { "isoform_ac": "A0A8V0ZQI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2/entry#A0A8V0ZQI9-1", "sequence": { "sequence": "MLVWDLLPSYLQYSQEIQTTGEDRKTRTETGDVHSDSILVRREMAEISSPVNIKEKINAIRSVVPNKSNNEIVLVLQQFDNNVDKAVQAFIDGSATQVLKEWNMTGKKKNNRRKRSKSKQHQGNKDAKNKNDGPDKASQEPQRIHGCHLNGCSKDSRSGDSANEKLEATSLENRSSQFVASAPGCPETTGKEREHQRVSVELSPKTVNGVEQHEPLQSSVQFQGNLGRPKSKSSSVKSSNATSQLETKPDDSVKKRGPNIEKSVKDLQRCTVSLTRYRMMIKEEVDNSVKKIKAAFAELHSCIIDKEVSLMAEIDKVKEEAMEILTARQKKAEELKRLTDLASQMAEAQLSELRAEIKHFVSERKYDEELGRSARFSCDTEQLKTQIQLCGEISHPKNNYSSRTPCSSVLSSLTSHATTGKQNTHTRKSSSNAKNSDNKTASTKVQSHHSSNPTESSSQGIPTNKQNGPSSQRRRFNPQHQNVRLNGSLKPQGTTNEADQNNVKSGSRSEHRRQQHNNFRPKNKGAMKNQEQSATARTTENVTHPEKSRRKHHTADTTDHRPFRGGVGRVSQCNLCPARMEVSPDTTVLSVPAVTLVA", "length": 598, "header": "tr|A0A8V0ZQI9-1|A0A8V0ZQI9_CHICK Computationally mapped isoform of Spermatosis associated serine rich 2 like OS=Gallus gallus OX=9031 GN=SPATS2L PE=1 SV=1 CANONICAL=A0A8V0ZQI2-1" }, "locus": { "chromosome": "7", "start_pos": 10784522, "end_pos": 10651627, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058721.1", "url": "https://www.ensembl.org/id/ENSGALT00010058721.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035699.1", "url": "https://www.ensembl.org/id/ENSGALP00010035699.1" } ] } }, { "isoform_ac": "A0A8V0ZVP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2/entry#A0A8V0ZVP8-1", "sequence": { "sequence": "MAEISSPVNIKEKINAIRSVVPNKSNNEIVLVLQQFDNNVDKAVQAFIDGSATQVLKEWNMTGKKKNNRRKRSKSKQHQGNKDAKNKNDGPDKASQEPQRIHGCHLNGCSKDSRSGDSANEKLEATSLENRSSQFVASAPGCPETTGKEREHQRVSVELSPKTVNGVEQHEPLQSSVQFQGNLGRPKSKSSSVKSSNATSQLETKPDDSVKKRGPNIEKSVKDLQRCTVSLTRYRMMIKEEVDNSVKKIKAAFAELHSCIIDKEVSLMAEIDKVKEEAMEILTARQKKAEELKRLTDLASQMAEAQLSELRAEIKVRHSLLLEHVSCLHKSEEGAIMLTCPGFSILLWTKG", "length": 351, "header": "tr|A0A8V0ZVP8-1|A0A8V0ZQI2_CHICK Computationally mapped isoform of Spermatosis associated serine rich 2 like OS=Gallus gallus OX=9031 GN=SPATS2L PE=1 SV=1 CANONICAL=A0A8V0ZQI2-1" }, "locus": { "chromosome": "7", "start_pos": 10779395, "end_pos": 10747632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058688.1", "url": "https://www.ensembl.org/id/ENSGALT00010058688.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035681.1", "url": "https://www.ensembl.org/id/ENSGALP00010035681.1" } ] } }, { "isoform_ac": "A0A8V0ZVQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2/entry#A0A8V0ZVQ3-1", "sequence": { "sequence": "MAEISSPVNIKEKINAIRSVVPNKSNNEIVLVLQQFDNNVDKAVQAFIDGSATQVLKEWNMTGKKKNNRRKRSKSKQHQGNKDAKNKNDGPDKASQEPQRIHGCHLNGCSKDSRSGDSANEKLEATSLENRSSQFVASAPGCPETTGKEREHQRVSVELSPKTVNGVEQHEPLQSSVQFQGNLGRPKSKSSSVKSSNATSQLETKPDDSVKKRGPNIEKSVKDLQRCTVSLTRYRMMIKEEVDNSVKKIKAAFAELHSCIIDKEVSLMAEIDKVKEEAMEILTARQKKAEELKRLTDLASQMAEAQLSELRAEIKHFVSERKYDEELGRSARFSCDTEQLKTQIQLCGERSKFPAVQEYSVGYSGAKVSHPKNNYSSRTPCSSVLSSLTSHATTGKQNTHTRKSSSNAKNSDNKTASTKVQSHHSSNPTESSSQGIPTNKQNGPSSQRRRFNPQHQNVRLNGSLKPQGTTNEADQNNVKSGSRSEHRRQQHNNFRPKNKGAMKNQEQSATARTTENVTHPEKSRRKHHTADTTDHRPFRGGVGRVSQCNLCPARMEVSPDTTVLSVPAVTLVA", "length": 573, "header": "tr|A0A8V0ZVQ3-1|A0A8V0ZQI2_CHICK Computationally mapped isoform of Spermatosis associated serine rich 2 like OS=Gallus gallus OX=9031 GN=SPATS2L PE=1 SV=1 CANONICAL=A0A8V0ZQI2-1" }, "locus": { "chromosome": "7", "start_pos": 10784522, "end_pos": 10747632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058694.1", "url": "https://www.ensembl.org/id/ENSGALT00010058694.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035686.1", "url": "https://www.ensembl.org/id/ENSGALP00010035686.1" } ] } }, { "isoform_ac": "A0A8V0ZVQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2/entry#A0A8V0ZVQ9-1", "sequence": { "sequence": "MKEIQTTGEDRKTRTETGDVHSDSILVRREMAEISSPVNIKEKINAIRSVVPNKSNNEIVLVLQQFDNNVDKAVQAFIDGSATQVLKEWNMTGKKKNNRRKRSKSKQHQGNKDAKNKNDGPDKASQEPQRIHGCHLNGCSKDSRSGDSANEKLEATSLENRSSQFVASAPGCPETTGKEREHQRVSVELSPKTVNGVEQHEPLQSSVQFQGNLGRPKSKSSSVKSSNATSQLETKPDDSVKKRGPNIEKSVKDLQRCTVSLTRYRMMIKEEVDNSVKKIKAAFAELHSCIIDKEVSLMAEIDKVKEEAMEILTARQKKAEELKRLTDLASQMAEAQLSELRAEIKHFVSERKYDEELGRSARFSCDTEQLKTQIQLCGEISHPKNNYSSRTPCSSVLSSLTSHATTGKQNTHTRKSSSNAKNSDNKTASTKVQSHHSSNPTESSSQGIPTNKQNGPSSQRRRFNPQHQNVRLNGSLKPQGTTNEADQNNVKSGSRSEHRRQQHNNFRPKNKGAMKNQEQSATARTTENVTHPEKSRRKHHTADTTDHRPFRGGVGRVSQCNLCPARMEVSPDTTVLSVPAVTLVA", "length": 585, "header": "tr|A0A8V0ZVQ9-1|A0A8V0ZQI2_CHICK Computationally mapped isoform of Spermatosis associated serine rich 2 like OS=Gallus gallus OX=9031 GN=SPATS2L PE=1 SV=1 CANONICAL=A0A8V0ZQI2-1" }, "locus": { "chromosome": "7", "start_pos": 10784522, "end_pos": 10711600, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058712.1", "url": "https://www.ensembl.org/id/ENSGALT00010058712.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035696.1", "url": "https://www.ensembl.org/id/ENSGALP00010035696.1" } ] } }, { "isoform_ac": "A0A8V0ZXS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2/entry#A0A8V0ZXS9-1", "sequence": { "sequence": "MAEISSPVNIKEKINAIRSVVPNKSNNEIVLVLQQFDNNVDKAVQAFIDGSATQVLKEWNMTGKKKNNRRKRSKSKQHQGNKDAKNKNDGPDKASQEPQRIHGCHLNGCSKDSRSGDSANEKLEATSLENRSSQFVASAPGCPETTGKEREHQRVSVELSPKTVNGVEQHEPLQSSVQFQGNLGRPKSKSSSVKSSNATSQLETKPDDSVKKRGPNIEKSVKDLQRCTVSLTRYRMMIKEEVDNSVKKIKAAFAELHSCIIDKEVSLMAEIDKVKEEAMEILTARQKKAEELKRLTDLASQMAEAQLSELRAEIKHFVSERKYDEELGRSARFSCDTEQLKTQIQLCGEISHPKNNYSSRTPCSSVLSSLTSHATTGKQNTHTRKSSSNAKNSDNKTASTKVQSHHSSNPTESSSQGIPTNKQVPKASIIFFSSASE", "length": 437, "header": "tr|A0A8V0ZXS9-1|A0A8V0ZQI2_CHICK Computationally mapped isoform of Spermatosis associated serine rich 2 like OS=Gallus gallus OX=9031 GN=SPATS2L PE=1 SV=1 CANONICAL=A0A8V0ZQI2-1" }, "locus": { "chromosome": "7", "start_pos": 10794482, "end_pos": 10747632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058716.1", "url": "https://www.ensembl.org/id/ENSGALT00010058716.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035698.1", "url": "https://www.ensembl.org/id/ENSGALP00010035698.1" } ] } }, { "isoform_ac": "A0A8V0ZZG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2/entry#A0A8V0ZZG1-1", "sequence": { "sequence": "MAEISSPVNIKEKINAIRSVVPNKSNNEIVLVLQQFDNNVDKAVQAFIDGSATQVLKEWNMTGKKKNNRRKRSKSKQHQGNKDAKNKNDGPDKASQEPQRIHGCHLNGCSKDSRSGDSANEKLEATSLENRSSQFVASAPGCPETTGKEREHQRVSVELSPKTVNGVEQHEPLQSSVQFQGNLGRPKSKSSSVKSSNATSQLETKPDDSVKKRGPNIEKSVKDLQRCTVSLTRYRMMIKEEVDNSVKKIKAAFAELHSCIIDKEVSLMAEIDKVKEEAISHPKNNYSSRTPCSSVLSSLTSHATTGKQNTHTRKSSSNAKNSDNKTASTKVQSHHSSNPTESSSQGIPTNKQNGPSSQRRRFNPQHQNVRLNGSLKPQGTTNEADQNNVKSGSRSEHRRQQHNNFRPKNKGAMKNQEQSATARTTENVTHPEKSRRKHHTADTTDHRPFRGGVGRVSQCNLCPARMEVSPDTTVLSVPAVTLVA", "length": 484, "header": "tr|A0A8V0ZZG1-1|A0A8V0ZQI2_CHICK Computationally mapped isoform of Spermatosis associated serine rich 2 like OS=Gallus gallus OX=9031 GN=SPATS2L PE=1 SV=1 CANONICAL=A0A8V0ZQI2-1" }, "locus": { "chromosome": "7", "start_pos": 10784522, "end_pos": 10747632, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058697.1", "url": "https://www.ensembl.org/id/ENSGALT00010058697.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035687.1", "url": "https://www.ensembl.org/id/ENSGALP00010035687.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q5U2T3-1", "protein_name": "SPATS2-like protein", "gene_name": "Spats2l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWSMTGKKKNNKRKRSKSKQHQGNKDAKDKGERPEVGPLQPQAPLVQNGHMNGCEKDSSSPDSAREKLALTPREKKISILEEPPRAQRGITEGSRLLQQKMSLDGNPKAIHGPSERSDGLQWSAGQPCNPSKPKAKTSPVKSNAPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMDILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQILICGEITHPKNNYSSRTPCSSLLPLLNTHAVASGKQGNFSRKSSGHNKPNEGKAANPKMVSGLPSTADACQQTMPTNKQQNGPSNQRRRFNPQYHNRLNGPAKSQGSGNEADPMVKSNNRHEHRRQPHNGFRPKNKGGAKNQEAPLGTKAPEAPPHSEKARRRQHAADNLETRPFRGNVGRVSQCNLCPTRIEVSTEATVLSVPAVTLVA", "length": 558 }, "evidence": [ { "id": "A0A8V0ZQI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZQI2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91WJ7-1", "protein_name": "SPATS2-like protein", "gene_name": "Spats2l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELNTHVNIKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEVGPLQPQAPLVQNGHMNGCEKDSSSPDSTREKLALTPREKKISILEEPPRAQRGVTEGGRLLQQKMSLDGNPRAIHGPSERSDGPQWSAGQPCNPSKPKAKTSPVKSNAPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMDILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQILICGEITHPKNSYSSRTPCSSLLPLLNTHAVASGKQGNFARKSSGHNKPSEGKAANPKMVSGLANTADACHQTMPTNKQQNGPSSQRRRFNPQYHNRLNGPAKSQGGGNEADPMAKSNSRHEHRRQPHNGFRPKNKGGAKNQEAPLGTKAPEAPPHSEKARRRQHAADNLEARPFRGNVSRVSQCNLCPSRIEVSTEATVLSVPAVTLVA", "length": 558 }, "evidence": [ { "id": "A0A8V0ZQI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZQI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUQ6-1", "protein_name": "SPATS2-like protein", "gene_name": "SPATS2L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAVLSVPAVTLVA", "length": 558 }, "evidence": [ { "id": "A0A8V0ZQI2", "url": "https://omabrowser.org/oma/group/A0A8V0ZQI2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 23, "end_pos": 25 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQJ2-1", "uniprot_ac": "A0A8V0ZQJ2", "uniprot_id": "A0A8V0ZQJ2_CHICK", "mass": { "chemical_mass": 61752.0, "monoisotopic_mass": 61752.0 }, "refseq": {}, "gene_names": [ { "name": "RPS6KB2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ], "protein_names": [ { "name": "Ribosomal protein S6 kinase beta-2", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2/entry#names_and_taxonomy" } ] }, { "name": "70 kDa ribosomal protein S6 kinase 2", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2/entry#names_and_taxonomy" } ] }, { "name": "p70 ribosomal S6 kinase beta", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2#function" }, { "database": "UniProtKB", "id": "ARBA00053693", "url": "https://www.uniprot.org/uniprotkb/ARBA00053693#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPS6KB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2", "locus": { "chromosome": "5", "start_pos": 177434, "end_pos": 172106, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022422", "url": "https://www.ensembl.org/id/ENSGALG00010022422" } ] } } ], "crossref": [ { "id": "A0A8V0ZQJ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05584", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05584", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQJ2", "url": "https://www.orthodb.org/?gene=A0A8V0ZQJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00433", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00433", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-198693", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198693", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGVFDIDLETEEGSDGEEPELGAEMEVEPRGNGLEPVGHYEEIEISESSVNNGPEHIGPHCFELLRVLGKGGYGKVFQVRKVQGTNTGKIFAMKVLKKAKIACNAKDTAHTRAERNILEAIKHPFIVDLIYAFQTGGKLYLILECLSGGELFMQLEREGIFLEDTACFYLSEITLALGHLHSNGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHDGAVTHTFCGTIEYMAPEILVHSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLVLPPYLTPDARDLLKKFLKRNPSQRVGGGPGDAADVQKHPFFRHINWEELLARRLDPPFKPCLQSEEDVSQFDARFTRQTPVDSPDDAVISESANQAFLGFTYVAPSVLESIKEGFSFQPKPGEVLPVRALQACRAHGAGAGGRHPARGHGPAAYRLRQEDAGGSGAAAQQRPERGSRVGTKRSPLLRSSPPNLQGDNRGCVRPWAPQDPPSLLRSRSLGCSHSQGCPTLPRHPLSPHSVFGVLTIPECGWSRSCCCGVSGAGGPPALPAPPAADVSMRGGRGGEGG", "length": 569, "header": "tr|A0A8V0ZQJ2-1|A0A8V0ZQJ2_CHICK Isoform 1 of Ribosomal protein S6 kinase beta-2 OS=Gallus gallus OX=9031 GN=RPS6KB2 PE=3 SV=1 CANONICAL=A0A8V0ZQJ2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2/entry#A0A8V0ZQJ2-1", "sequence": { "sequence": "MAGVFDIDLETEEGSDGEEPELGAEMEVEPRGNGLEPVGHYEEIEISESSVNNGPEHIGPHCFELLRVLGKGGYGKVFQVRKVQGTNTGKIFAMKVLKKAKIACNAKDTAHTRAERNILEAIKHPFIVDLIYAFQTGGKLYLILECLSGGELFMQLEREGIFLEDTACFYLSEITLALGHLHSNGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHDGAVTHTFCGTIEYMAPEILVHSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTIDKILKGKLVLPPYLTPDARDLLKKFLKRNPSQRVGGGPGDAADVQKHPFFRHINWEELLARRLDPPFKPCLQSEEDVSQFDARFTRQTPVDSPDDAVISESANQAFLGFTYVAPSVLESIKEGFSFQPKPGEVLPVRALQACRAHGAGAGGRHPARGHGPAAYRLRQEDAGGSGAAAQQRPERGSRVGTKRSPLLRSSPPNLQGDNRGCVRPWAPQDPPSLLRSRSLGCSHSQGCPTLPRHPLSPHSVFGVLTIPECGWSRSCCCGVSGAGGPPALPAPPAADVSMRGGRGGEGG", "length": 569, "header": "tr|A0A8V0ZQJ2-1|A0A8V0ZQJ2_CHICK Isoform 1 of Ribosomal protein S6 kinase beta-2 OS=Gallus gallus OX=9031 GN=RPS6KB2 PE=3 SV=1 CANONICAL=A0A8V0ZQJ2-1" }, "locus": { "chromosome": "5", "start_pos": 176539, "end_pos": 172236, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054493.1", "url": "https://www.ensembl.org/id/ENSGALT00010054493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010032915.1", "url": "https://www.ensembl.org/id/ENSGALP00010032915.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-198693", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-198693", "resource": "Reactome", "description": "AKT phosphorylates targets in the nucleus" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "TORC1 signaling", "id": "GO:0038202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038202", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ], "pmid": "" }, { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A8V1AMK5-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "A0A1D5P517-1", "F1NB57-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "P67962-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0ZFM2-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V1AIY7-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0YRC9-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "A0A1D5PUY5-1", "F1P4G3-1", "A0A8V0ZMK1-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "E1C093-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0XI18-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XQQ4-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A1D5PUY5-1", "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YRC9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", "A0A8V0X1Q7-1", "A0A8V0Y935-1", "A0A8V0YM96-1", "A0A8V0YF83-1", "A0A8V0YJP9-1", "A0A8V1AKW4-1", "A0A1D5P517-1", "A0A8V0ZSB4-1", "F1NBT0-1", "P18652-1", "P21868-1", "P21869-1", "P53666-1", "P79996-1", "Q5F3W3-1", "Q5ZJS0-1", "Q5ZKN1-1", "Q5ZLL1-1", "A0A8V0XCS0-1", "A0A8V0XNK8-1", "A0A8V0XLV6-1", "A0A8V0XDR5-1", "E1BYH2-1", "F1NB57-1", "E1BQN6-1", "A0A8V0XU71-1", "Q5ZJH6-1", "A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-199839", "name": "AKT can phosphorylate RSK", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "nucleoplasm", "input_participant_list": [ "R-GGA-199877" ], "output_participant_list": [ "R-GGA-199844" ], "enzyme_list": [ "A0A3Q2U4X3-1", "A0A8V0ZQJ2-1" ], "evidence": [ { "id": "R-GGA-199839", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-199839" } ] } ], "reaction_participants": [ { "participant_id": "R-GGA-199844", "participant_name": "phospho-p-S15,S356-RPS6KB2 [nucleoplasm]", "crossref": [ { "id": "ENSGALT00010054493", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALG00010022422", "database": "ENSEMBL", "url": "" }, { "id": "A0A8V0ZQJ2", "database": "UniProt", "url": "" }, { "id": "ENSGALP00010032915", "database": "ENSEMBL", "url": "" } ] }, { "participant_id": "R-GGA-199877", "participant_name": "RPS6KB2 [nucleoplasm]", "crossref": [ { "id": "A0A8V0ZQJ2", "database": "UniProt", "url": "" }, { "id": "ENSGALG00010022422", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALP00010032915", "database": "ENSEMBL", "url": "" }, { "id": "ENSGALT00010054493", "database": "ENSEMBL", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A3Q2TY19" } ] } ] }, { "uniprot_ac": "A0A3Q2U4X3", "gene_name": "AKT1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U4X3" } ] } ] }, { "uniprot_ac": "A0A3Q2U592", "gene_name": "DCLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2U592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U592" } ] } ] }, { 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] } ] }, { "uniprot_ac": "A0A3Q2UI62", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] } ] }, { "uniprot_ac": "A0A3Q3A664", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] } ] }, { "uniprot_ac": "A0A3Q3AAD7", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] } ] }, { "uniprot_ac": "A0A3Q3B2F1", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] } ] }, { "uniprot_ac": "A0A8V0X1Q7", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XBZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XBZ0" } ] } ] }, { "uniprot_ac": "A0A8V0XCS0", "gene_name": "PRKG2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0XCS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCS0" } ] } ] }, { "uniprot_ac": "A0A8V0XCV5", "gene_name": "MAP3K7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y4L8" } ] } ] }, { "uniprot_ac": "A0A8V0Y6K1", "gene_name": "MAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y6K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6K1" } ] } ] }, { "uniprot_ac": "A0A8V0Y7C3", "gene_name": "DAPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { "uniprot_ac": "A0A8V0YCY4", "gene_name": "AURKB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY4" } ] } ] }, { "uniprot_ac": "A0A8V0YCY8", "gene_name": "RIOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] } ] }, { "uniprot_ac": "A0A8V0Z466", "gene_name": "MAP3K19", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] } ] }, { "uniprot_ac": "A0A8V0Z6K4", "gene_name": "PIK3R4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6K4" } ] } ] }, { "uniprot_ac": "A0A8V0Z6T1", "gene_name": "ERN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z6T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6T1" } ] } ] }, { "uniprot_ac": "A0A8V0Z807", "gene_name": "NEK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA06" } ] } ] }, { "uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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"gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": 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"https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": 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[ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] 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{ "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTRAAQCLSLHLQAALPAAAPCRAPHSALPNRPRVAQIPARRPNPVLPPALPGGCRLSWMASTSARQHLLLQTPLPDLAPFRELPRALAAPHPHWHQEQTAQTSGMSRTPLSSAPRGCSMRLGGTPRLLRALCILSVLAGLLPHGTAQWFYPLGSEDTTPEPGTSPATPTLPTPDGEEGAADTEPMKKLPLSKPPLGTASRRREPSARTKGQGHAPLRTQAQHNHPTASPQIFEGSADEEEFLQIKTTPKGLPQRVPTAPRPDVALQMHNGSNCICPARPAPPGPKGEKGDRGFPGERGQPGLSGERGRTGSPGPPGHQGPRGPPGPPGPPGPPGSPGAGGARSPPAPAALPKESERELGAASPTGKPGPPGAPGLPGPPGPPGPPGYPGHEGSPGLPGREGKPGPPGPPGAVGPPGFPGSEGAPGSPGLAGSDGPPGAPGLPGTQGPPGAPGHEGPPGPPGPVSFPGKPGLRGEPGFPGSKGEKGEQGLPGMPGSPGRTGEMGAPGMPGPMGPPGPPGDNRCEMRHAGHHGAAGPPGPKGEKGDPGERGCCYGEPGCKPGHLPFPSPGSQPSAWYQQGPRGPPGPPGPPGPPGAPGLLYFNRVYPTRGQQPCKQPAAASAGWAVASPDADVPHSEPLEPSADFRRQTWVFRSKELMLKSSSAVPEGSLVYVREGNNAFVRTPRGWSRLLLEDSESLFAGDDPSASTPQYQEAKQAQTRGPNTEPSSGARTDSPVLEEDGAGLPSTLPTTAAPRMPSLRLAALNAPLSGDMSGIRGADLQCYRQSQEARLYGTFRAFLSAPSQDLASIVKRTDRTLPIVNLKGQLLARSWSALLQSQAGAAPRSPIYAFNGRNVLTDALWPRGMAWHGSTPRGGHAKRRDCQGWRSSGPGEGLAAPLAQGRLLAGQRRNCSEALVLLCVEVAFPYRHMW", 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"MRTRAAQCLSLHLQAALPAAAPCRAPHSALPNRPRVAQIPARRPNPVLPPALPGGCRLSWMASTSARQHLLLQTPLPDLAPFRELPRALAAPHPHWHQEQTAQTSGMSRTPLSSAPRGCSMRLGGTPRLLRALCILSVLAGLLPHGTAQWFYPLGSEDTTPEPGTSPATPTLPTPDGEEGAADTEPMKKLPLSKPPLGTASRRREPSARTKGQGHAPLRTQAQHNHPTASPQIFEGSADEEEFLQIKTTPKGLPQRVPTAPRPDVALQMHNGSNCICPARPAPPGPKGEKGDRGFPGERGQPGLSGERGRTGSPGPPGHQGPRGPPGPPGPPGPPGSPGAGGARSPPAPAALPKESERELGAASPTGKPGPPGAPGLPGPPGPPGPPGYPGHEGSPGLPGREGKPGPPGPPGAVGPPGFPGSEGAPGSPGLAGSDGPPGAPGLPGTQGPPGAPGHEGPPGPPGPVSFPGKPGLRGEPGFPGSKGEKGEQGLPGMPGSPGRTGEMGAPGMPGPMGPPGPPGDNRCEMRHAGHHGAAGPPGPKGEKGDPGERGCCYGEPGCKPGHLPFPSPGSQPSAWYQQGPRGPPGPPGPPGPPGAPGLLYFNRVYPTRGQQPCKQPAAASAGWAVASPDADVPHSEPLEPSADFRRQTWVFRSKELMLKSSSAVPEGSLVYVREGNNAFVRTPRGWSRLLLEDSESLFAGDDPSASTPQYQEAKQAQTRGPNTEPSSGARTDSPVLEEDGAGLPSTLPTTAAPRMPSLRLAALNAPLSGDMSGIRGADLQCYRQSQEARLYGTFRAFLSAPSQDLASIVKRTDRTLPIVNLKGQLLARSWSALLQSQAGAAPRSPIYAFNGRNVLTDALWPRGMAWHGSTPRGGHAKRRDCQGWRSSGPGEGLAAPLAQGRLLAGQRRNCSEALVLLCVEVAFPYRHMW", "length": 930, "header": "tr|A0A8V0ZQJ6-1|A0A8V0ZQJ6_CHICK Isoform 1 of Collagen alpha-1(XVIII) chain OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZQJ6-1" }, "locus": { "chromosome": "27", "start_pos": 4441567, "end_pos": 4433196, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054770.1", "url": "https://www.ensembl.org/id/ENSGALT00010054770.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033102.1", "url": "https://www.ensembl.org/id/ENSGALP00010033102.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-GGA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-GGA-216083", "name": "", "url": 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"Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 910, "end_pos": 912, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ6" }, { "id": "PF20010", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Collagen type XV/XVIII trimerization", "eco_id": "ECO_0000259", "start_pos": 651, "end_pos": 694, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ6" }, { "id": "PF06482", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06482" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Collagenase NC10/endostatin", "eco_id": "ECO_0000259", "start_pos": 759, "end_pos": 924, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 }, { "start_pos": 910, "end_pos": 912 } ] }, "class_list": [], 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQL8-1", "uniprot_ac": "A0A8V0ZQL8", "uniprot_id": "A0A8V0ZQL8_CHICK", "mass": { "chemical_mass": 79915.0, "monoisotopic_mass": 79915.0 }, "refseq": { "ac": "XP_421139", "name": "RNA polymerase-associated protein RTF1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421139" }, "gene_names": [ { "name": "RTF1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" } ] }, { "name": "RTF1", "type": "synonym", "evidence": [ { "id": "XP_421139", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421139" } ] } ], "protein_names": [ { "name": "RNA polymerase-associated protein RTF1 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8/entry#names_and_taxonomy" } ] }, { "name": "RNA polymerase-associated protein RTF1 homolog", "type": "synonym", "evidence": [ { "id": "XP_421139", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421139" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 19, 2013 this sequence version replaced XP_421139.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421139", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421139" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RTF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8", "locus": { "chromosome": "5", "start_pos": 24140886, "end_pos": 24112463, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022521", "url": "https://www.ensembl.org/id/ENSGALG00010022521" } ] } } ], "crossref": [ { "id": "A0A8V0ZQL8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "423215", "url": 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{ "id": "PTHR13115:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13115:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03126", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03126", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421139", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421139", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGALCVPVGRAARGRPGRSERRAAAGGEGRGEAASAMVKKRKGRVLIDSDTEDSGSEENLDQELLSLAKRKRSDSEEKEPPASKPTASSDSETSDSDDEWTVGGSKNKKKGKAGKAEKKGAMKKQMNKAASSGSSDKDSSAESSAPEEGEVSDSESNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRSSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGSDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKEVSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHSMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKDMSKGQGKDKDVNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 707, "header": "tr|A0A8V0ZQL8-1|A0A8V0ZQL8_CHICK Isoform 1 of RNA polymerase-associated protein RTF1 homolog OS=Gallus gallus OX=9031 GN=RTF1 PE=1 SV=1 CANONICAL=A0A8V0ZQL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8/entry#A0A8V0ZQL8-1", "sequence": { "sequence": "MRGALCVPVGRAARGRPGRSERRAAAGGEGRGEAASAMVKKRKGRVLIDSDTEDSGSEENLDQELLSLAKRKRSDSEEKEPPASKPTASSDSETSDSDDEWTVGGSKNKKKGKAGKAEKKGAMKKQMNKAASSGSSDKDSSAESSAPEEGEVSDSESNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRSSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGSDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKEVSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHSMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKDMSKGQGKDKDVNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 707, "header": "tr|A0A8V0ZQL8-1|A0A8V0ZQL8_CHICK Isoform 1 of RNA polymerase-associated protein RTF1 homolog OS=Gallus gallus OX=9031 GN=RTF1 PE=1 SV=1 CANONICAL=A0A8V0ZQL8-1" }, "locus": { "chromosome": "5", "start_pos": 24138149, "end_pos": 24112485, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054810.1", "url": "https://www.ensembl.org/id/ENSGALT00010054810.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033127.1", "url": "https://www.ensembl.org/id/ENSGALP00010033127.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423215", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423215", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AGX2-1", "protein_name": "RNA polymerase-associated protein RTF1 homolog", "gene_name": "Rtf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGRLCVGRAAAVAAAVVAAVAVPLAGGQEGSPDGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKVEKKGAMKKQANKAASSGSSDRDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEDDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKEFSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMRNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGALPDAPKEVSKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 715 }, "evidence": [ { "id": "A0A8V0ZQL8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQL8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABI0P1E3-1", "protein_name": "RNA polymerase-associated protein RTF1 homolog", "gene_name": "RTF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGRLCVGRTAAAAAAATAAVAVPLAGGQEGSPGGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSNSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKKRFEIRKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTTSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGSDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMNKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 714 }, "evidence": [ { "id": "A0A8V0ZQL8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQL8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A2AQ19-1", "protein_name": "RNA polymerase-associated protein RTF1 homolog", "gene_name": "Rtf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGRLCVGRAAAVAAAVAAAAVAVPLAGGQEGSQGGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKTRKVEKKGAMKKQANKAASSGSSDRDSSAESSAPEEGEVSDSESSSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEDDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMRNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMSKGQGKDKDLNSKTASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 715 }, "evidence": [ { "id": "A0A8V0ZQL8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQL8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P53064-1", "protein_name": "RNA polymerase-associated protein RTF1", "gene_name": "RTF1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSDLDEDLLALAGADESEEEDQVLTTTSAKRAKNNDQSLSKKRRIEVGSVEDDDEEDDYNPYSVGNADYGSEEEEEANPFPLEGKYKDESDREHLESLPEMERETLLFERSQIMQKYQERKLFRARGRDMKEQQQRAKNDEDSRKTRASTRSTHATGHSDIKASKLSQLKKQRARKNRHYSDNEDEDDEEDYREEDYKDDEGSEYGDDEEYNPFDRRDTYDKREEVEWAEEEDEQDREPEISDFNKLRIGRSFVAKFCFYPGFEDAVKGCYGRVNVGTDKRTGKTSYRMVRIERVFLQKPYNMGKFYTNQYFGVTQGKDRKVFQMNYFSDGLFAEDEYQRYLRALDNSQMIKPSLHSLSNKTKEVMDFVNTPLTDKTTDEVVRHRMQFNKKLSGTNAVLEKTVLREKLQYAKETNNEKDIAKYSAQLRNFEKRMSVYEKHHENDQSDIKKLGELTSKNRKLNMSNIRNAEHVKKEDSNNFDSKSDPFSRLKTRTKVYYQEIQKEENAKAKEIAQQEKLQEDKDAKDKREKELLVAQFRRLGGLERMVGELDIKFDLKF", "length": 558 }, "evidence": [ { "id": "A0A8V0ZQL8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQL8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q92541-1", "protein_name": "RNA polymerase-associated protein RTF1 homolog", "gene_name": "RTF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGRLCVGRAAAAAAAVAVPLAGGQEGSPGGGRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMSKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "length": 710 }, "evidence": [ { "id": "A0A8V0ZQL8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQL8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C950-1", "protein_name": "Protein RTF1 homolog", "gene_name": "VIP5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGDLENLLLEAAGRTNSAGRSRHPPSSRRREGSYSDGSSDSRDDSDEDRGYASRKPSGSQVPLKKRLEAEREDRAARVEGGYGDGPSDREGDSSEESDFGDDLYKNEEDRQKLAGMTEFQREMILSERADKKGDKNFTEKLRSKRESEKTPVSKKETQPLPASRGVRSSARSADRAAAKDDALNELRAKRMKQQDPAALRKLRDASKGGSGSRDFSSTKRKPLASSNLSSSSQSDSDSRSQSDDEGSNGGMLDSDDDRSDVPTFEDVKEVTIRRSKLAKWLMEPFFEELIVGCFVRVGIGRSKSGPIYRLCWVKNVDATDPDKTYKLENKTTHKYLNVVWGNETSAARWQMAMISDGHPLEEEYRQWIREVERTNGRMPTKQDISEKKEAIQRTNSFVYSAETVKQMLQEKKSASVRPMNVAAEKDRLRKELEIAQSKNDEAGVERIKSKIKQLDASRNKKGVDKKALKLAEMNKKNRAENFKNASEVKSITASLKAGEAGYDPFSRRWTRSSNYYNGKNKGKDGEENEAAVAAAVETNGADAGAGVEATEAALEAAAEAGKLIDTRAPIGQGAEHNQLHNFELSLSLTALQKYGGPQGVQKAFMARKQLTEATVGCRVAENDGKRHGLTLTVSDYKRRRGLL", "length": 643 }, "evidence": [ { "id": "A0A8V0ZQL8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQL8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W261-1", "protein_name": "RNA polymerase-associated protein Rtf1", "gene_name": "Rtf1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKRRTQSLIDSNSSDSDSESETNLESDLMSLAKKRKKPQTAAKSSSRSDSDSDWANNKAGAPSSKKKKRQKPSRDSSSSESNWDDDSQDERQPARQSPAQTQQEHKPPEQASQPAQLSEQEEGEVSDSDSDKSKSNSSSSGSDSSSSSSSSDSEFDDGFDDDLMGDDEDRRRLNGLSEKERETEIYKRIEQREIMRTRWEIERKLKLARRGEKNQEKSKNKGERAKKKKEKREKKARKAREAQAPLPTQASTSTLLDVEPKPSNEVRSASPLSTPALNRDAASTSAAVASIMPDDAASSAGVSDYFDHKERSKERKKNVEANKTDDKRSNAMALLKAKREGKAKREEEEAKRMAEKDRDDDKEELDSVSGCKSAVKLKASEIYSDDSGSSDWDEEEKPAGKRSRSNSSKASSESEDEEKAPQRPVFITTREDLNKLRLSRYKMERFVNLPIFESTVLNCFVRISIGNNGQKPVYRVAEIVGVVETGKIYSLGTTRTNRGLRLKHGTQERVFRLEFISNQEFTENEFNKWNEVCQQSHVQMPTIDLIAIKQNDIKKALNYEFKDEDVDKIVEEKNRFRNRPTNYAMKKTCLMKERDAAMLRGDYDIAQDLGQQIDELENRASELDKRRSHTLNLISYINDRNRKKNVEDAEKAILEEARANKGLKISDPFTRRITQPRMGFKGAKKDEDDMQLAPLPPPPPGKKRPNEAGTSSASVRSTDSKDYSLYSLHDFDIDLDVPLPVNTNSVPKPASKPAETVSKRSLNLEDYKKKRGLI", "length": 775 }, "evidence": [ { "id": "A0A8V0ZQL8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQL8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" } ], "pmid": "" }, { "name": "endodermal cell fate commitment", "id": "GO:0001711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001711", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" } ], "pmid": "" }, { "name": "Cdc73/Paf1 complex", "id": "GO:0016593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" } ], "pmid": "" }, { "name": "RNA polymerase II C-terminal domain phosphoserine binding", "id": "GO:1990269", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990269", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQL8" }, { "id": "PS51360", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51360" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Plus3", "eco_id": "ECO_0000259", "start_pos": 350, "end_pos": 481, "start_aa": "Val", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 553, "end_pos": 555 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQM0-1", "uniprot_ac": "A0A8V0ZQM0", "uniprot_id": "A0A8V0ZQM0_CHICK", "mass": { "chemical_mass": 35761.0, "monoisotopic_mass": 35761.0 }, "refseq": {}, "gene_names": [ { "name": "PLPPR5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0" } ] } ], "protein_names": [ { "name": "Phospholipid phosphatase-related protein type 5", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0/entry#names_and_taxonomy" } ] }, { "name": "Lipid phosphate phosphatase-related protein type 5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLPPR5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0", "locus": { "chromosome": "8", "start_pos": 12129388, "end_pos": 11896248, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024104", "url": "https://www.ensembl.org/id/ENSGALG00010024104" } ] } } ], "crossref": [ { "id": "A0A8V0ZQM0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424477", "url": "https://www.ncbi.nlm.nih.gov/gene/424477", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000326", "database": 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"R-GGA-419408", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-419408", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZM2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A393", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A393", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A393-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A393-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVIMAGTVMLAYYFEYTDTFAVNVQGFFCYEGAYRKPYPGPEDSSAVPPVLLYSLTAGVPVLVIIVGETAVFCLQLATKDFENQEKTILTGDCCYINPLVRRTIRFLGIYAFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCKQYTQFISSAHACTGNPDLIMKARKTFPSKEAALSIYAAMYLAMYITSTVKARGTRLAKPVLCLGLMCLAFLTGINRVAEYRNHWSDVIAGFIIGISIAVFLVVCVVNNFRGRQPEHEHSHTDNLAQMPMISIPRVESPLEKLQILAPLCWHSTVMHLKTKTLRALLEQNQLYK", "length": 322, "header": "tr|A0A8V0ZQM0-1|A0A8V0ZQM0_CHICK Isoform 1 of Phospholipid phosphatase-related protein type 5 OS=Gallus gallus OX=9031 GN=PLPPR5 PE=3 SV=1 CANONICAL=A0A8V0ZQM0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0/entry#A0A8V0ZQM0-1", "sequence": { "sequence": "MVIMAGTVMLAYYFEYTDTFAVNVQGFFCYEGAYRKPYPGPEDSSAVPPVLLYSLTAGVPVLVIIVGETAVFCLQLATKDFENQEKTILTGDCCYINPLVRRTIRFLGIYAFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCKQYTQFISSAHACTGNPDLIMKARKTFPSKEAALSIYAAMYLAMYITSTVKARGTRLAKPVLCLGLMCLAFLTGINRVAEYRNHWSDVIAGFIIGISIAVFLVVCVVNNFRGRQPEHEHSHTDNLAQMPMISIPRVESPLEKLQILAPLCWHSTVMHLKTKTLRALLEQNQLYK", "length": 322, "header": "tr|A0A8V0ZQM0-1|A0A8V0ZQM0_CHICK Isoform 1 of Phospholipid phosphatase-related protein type 5 OS=Gallus gallus OX=9031 GN=PLPPR5 PE=3 SV=1 CANONICAL=A0A8V0ZQM0-1" }, "locus": { "chromosome": "8", "start_pos": 12128384, "end_pos": 12051240, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058767.1", "url": "https://www.ensembl.org/id/ENSGALT00010058767.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035734.1", "url": "https://www.ensembl.org/id/ENSGALP00010035734.1" } ] } }, { "isoform_ac": "A0A8V0ZZM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0/entry#A0A8V0ZZM2-1", "sequence": { "sequence": "MMVIMAGTVMLAYYFEYTDTFAVNVQGFFCYEGAYRKPYPGPEDSSAVPPVLLYSLTAGVPVLVIIVGETAVFCLQLATKDFENQEKTILTGDCCYINPLVRRTIRFLGIYAFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCKQYTQFISSAHACTGNPDLIMKARKTFPSKEAALSIYAAMYLAMYITSTVKARGTRLAKPVLCLGLMCLAFLTGINRVAEYRNHWSDVIAGFIIGISIAVFLVVCVVNNFRGRQPEHEHSHTDNLAQMPMISIPRVESPLEKNHITAFAEVT", "length": 301, "header": "tr|A0A8V0ZZM2-1|A0A8V0ZQM0_CHICK Computationally mapped isoform of Phospholipid phosphatase-related protein type 5 OS=Gallus gallus OX=9031 GN=PLPPR5 PE=3 SV=1 CANONICAL=A0A8V0ZQM0-1" }, "locus": { "chromosome": "8", "start_pos": 12092331, "end_pos": 11975852, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058776.1", "url": "https://www.ensembl.org/id/ENSGALT00010058776.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035742.1", "url": "https://www.ensembl.org/id/ENSGALP00010035742.1" } ] } }, { "isoform_ac": "A0A8V1A393-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0/entry#A0A8V1A393-1", "sequence": { "sequence": "MRVPSPLTSMLYFQMVIMAGTVMLAYYFEYTDTFAVNVQGFFCYEGAYRKPYPGPEDSSAVPPVLLYSLTAGVPVLVIIVGETAVFCLQLATKDFENQEKTILTGDCCYINPLVRRTIRFLGIYAFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCKQYTQFISSAHACTGNPDLIMKARKTFPSKEAALSIYAAMYLAMYITSTVKARGTRLAKPVLCLGLMCLAFLTGINRVAEYRNHWSDVIAGFIIGISIAVFLVVCVVNNFRGRQPEHEHSHTDNLAQMPMISIPRVESPLEK", "length": 304, "header": "tr|A0A8V1A393-1|A0A8V0ZQM0_CHICK Computationally mapped isoform of Phospholipid phosphatase-related protein type 5 OS=Gallus gallus OX=9031 GN=PLPPR5 PE=3 SV=1 CANONICAL=A0A8V0ZQM0-1" }, "locus": { "chromosome": "8", "start_pos": 12085160, "end_pos": 12051198, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058763.1", "url": "https://www.ensembl.org/id/ENSGALT00010058763.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035730.1", "url": "https://www.ensembl.org/id/ENSGALP00010035730.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-419408", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-419408", "resource": "Reactome", "description": "Lysosphingolipid and LPA receptors" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MU59-1", "protein_name": "Phospholipid phosphatase-related protein type 5", "gene_name": "PLPPR5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLRPAALTSSMLYFQMVIMAGTVMLAYYFEYTDTFTVNVQGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEKTILTGDCCYINPLVRRTVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCQQYTQFISGEEACTGNPDLIMRARKTFPSKEAALSVYAAMYLTMYITNTIKAKGTRLAKPVLCLGLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKGRQPENEHTHTDSLAQLPMISIPRVESPLEKVTSVQNHITAFAEVT", "length": 321 }, "evidence": [ { "id": "A0A8V0ZQM0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQM0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S552-1", "protein_name": "Phospholipid phosphatase-related protein type 5", "gene_name": "PLPPR5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLLPAALTSSMLYFQMVIMAGTVMLAYYFEYTDTFTVNVQGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEKTILTGDCCYINPLVRRTVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCQQYTQFISGEEACTGNPDLIMRARKTFPSKEAALSVYAAMYLTMYITNTIKAKGTRLAKPVLCLGLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKGRQPENEHIHTDNLAQMPMISIPRVESPLEKVTSVQNHITAFAEVT", "length": 321 }, "evidence": [ { "id": "A0A8V0ZQM0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQM0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q32ZL2-1", "protein_name": "Phospholipid phosphatase-related protein type 5", "gene_name": "PLPPR5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLLPAALTSSMLYFQMVIMAGTVMLAYYFEYTDTFTVNVQGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEKTILTGDCCYINPLVRRTVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCQQYTQFISGEEACTGNPDLIMRARKTFPSKEAALSVYAAMYLTMYITNTIKAKGTRLAKPVLCLGLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKGRQAENEHIHMDNLAQMPMISIPRVESPLEKVTSVQNHITAFAEVT", "length": 321 }, "evidence": [ { "id": "A0A8V0ZQM0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQM0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BJ52-1", "protein_name": "Phospholipid phosphatase-related protein type 5", "gene_name": "Plppr5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLLPVALISSMLYFQMVIMAGTVMLAYYFEYTDTFTVNVQGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEKTILTGDCCYINPLVRRTVRFLGIYAFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCQQYTQFISGEEACTGNPDLIMRARKTFPSKEAALSVYAATYLTMYITSTIKAKGTRLAKPVLCLGLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKGRQPENGHIHRDNVARMPMTNIPRVESPLEKVTSLQNHVTAFAEVT", "length": 321 }, "evidence": [ { "id": "A0A8V0ZQM0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQM0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0" } ], "pmid": "" }, { "name": "phospholipid metabolic process", "id": "GO:0006644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006644", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0" } ], "pmid": "" }, { "name": "phospholipid dephosphorylation", "id": "GO:0046839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidate phosphatase activity", "id": "GO:0008195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008195", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQM0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQM0" }, { "id": "SM00014", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidic acid phosphatase type 2/haloperoxidase", "eco_id": "ECO_0000259", "start_pos": 107, "end_pos": 251, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQR3-1", "uniprot_ac": "A0A8V0ZQR3", "uniprot_id": "A0A8V0ZQR3_CHICK", "mass": { "chemical_mass": 41149.0, "monoisotopic_mass": 41149.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZQR3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQR3", "database": "AlphaFoldDB", "categories": [] }, { "id": "PTHR22656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22656:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22656:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQR3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "DYKPSPPTLLNLLSSPCLPAAFSDAFNFFPKDLDGNINLQNLEVLAKQLGISFDGQEAHKKLVCADADGECIRPCMDCIVHVKRPLSLCLPSPEHCCTEMYFKAEAVLELSCFRQKFRDCSSEQAWTDADFLVSHKKNNNKNRKVLVYPLSSFVSAARISLMKEKEATAYLERLKERVPESESPYARVPVFPLISKQDAKTLVKPKKDMQKQTKQRKKEPLASKESRFSCKKKQVQEVRDMGGASATCNSIKGSLRTSLKTYVLFDQAAAKDVQVAQRYRRNLALRKHASLLKLWHKINGAQISRQTGSRRFCHTFSTYSWSWNACRELVTAEELQAQDRRHRRFQPATRQPPWKKWLF", "length": 359, "header": "tr|A0A8V0ZQR3-1|A0A8V0ZQR3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZQR3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR3/entry#A0A8V0ZQR3-1", "sequence": { "sequence": "DYKPSPPTLLNLLSSPCLPAAFSDAFNFFPKDLDGNINLQNLEVLAKQLGISFDGQEAHKKLVCADADGECIRPCMDCIVHVKRPLSLCLPSPEHCCTEMYFKAEAVLELSCFRQKFRDCSSEQAWTDADFLVSHKKNNNKNRKVLVYPLSSFVSAARISLMKEKEATAYLERLKERVPESESPYARVPVFPLISKQDAKTLVKPKKDMQKQTKQRKKEPLASKESRFSCKKKQVQEVRDMGGASATCNSIKGSLRTSLKTYVLFDQAAAKDVQVAQRYRRNLALRKHASLLKLWHKINGAQISRQTGSRRFCHTFSTYSWSWNACRELVTAEELQAQDRRHRRFQPATRQPPWKKWLF", "length": 359, "header": "tr|A0A8V0ZQR3-1|A0A8V0ZQR3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZQR3-1" }, "locus": { "chromosome": "27", "start_pos": 1985020, "end_pos": 1980983, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055893.1", "url": "https://www.ensembl.org/id/ENSGALT00010055893.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033835.1", "url": "https://www.ensembl.org/id/ENSGALP00010033835.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQR9-1", "uniprot_ac": "A0A8V0ZQR9", "uniprot_id": "A0A8V0ZQR9_CHICK", "mass": { "chemical_mass": 48099.0, "monoisotopic_mass": 48099.0 }, "refseq": {}, "gene_names": [ { "name": "NAP1L4", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9" } ] } ], "protein_names": [ { "name": "Nucleosome assembly protein 1 like 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NAP1L4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9", "locus": { "chromosome": "5", "start_pos": 12741627, "end_pos": 12715321, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024112", "url": "https://www.ensembl.org/id/ENSGALG00010024112" } ] } } ], "crossref": [ { "id": "A0A8V0ZQR9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQR9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006446", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006446", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423087", "url": "https://www.ncbi.nlm.nih.gov/gene/423087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423087", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423087", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSGDFMY", "url": "https://omabrowser.org/oma/group/YSGDFMY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQR9", "url": "https://www.orthodb.org/?gene=A0A8V0ZQR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZS0", "url": "https://www.orthodb.org/?gene=A0A8V0ZZS0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A3D3", "url": "https://www.orthodb.org/?gene=A0A8V1A3D3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P1B7", "url": "https://www.orthodb.org/?gene=F1P1B7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00956", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00956", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZQR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZS0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3D3", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A3D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3D3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1B7", "url": "https://www.uniprot.org/uniprotkb/F1P1B7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P1B7-1", "url": "https://www.uniprot.org/uniprotkb/F1P1B7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRDGFLGGGAARVSLRGVWRCWGDAARAGTERKTLKRQTSLKVDTGTQMADNSSSKAEDTASDSVEAAKNASDKKEKLADQVMQNPQVLAALQERLDNTALTPSSYIETLPKAVKRRIDALKQLQVKCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFINGEAEPTDAESEWHSENEEEEKLAGDLKNVVVIEEKAEAEEINVKGIPDFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSEPGQPMSFSLEFHFGPNDYFSNTVLTKTYKMKSEPDKTDPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNDSFFNFFNPIKVSGDGESLDEDSEFTLAADFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGEEEGEEEEDAESDPKV", "length": 424, "header": "tr|A0A8V0ZQR9-1|A0A8V0ZQR9_CHICK Isoform 1 of Nucleosome assembly protein 1 like 4 OS=Gallus gallus OX=9031 GN=NAP1L4 PE=1 SV=1 CANONICAL=A0A8V0ZQR9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9/entry#A0A8V0ZQR9-1", "sequence": { "sequence": "MRDGFLGGGAARVSLRGVWRCWGDAARAGTERKTLKRQTSLKVDTGTQMADNSSSKAEDTASDSVEAAKNASDKKEKLADQVMQNPQVLAALQERLDNTALTPSSYIETLPKAVKRRIDALKQLQVKCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFINGEAEPTDAESEWHSENEEEEKLAGDLKNVVVIEEKAEAEEINVKGIPDFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSEPGQPMSFSLEFHFGPNDYFSNTVLTKTYKMKSEPDKTDPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNDSFFNFFNPIKVSGDGESLDEDSEFTLAADFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGEEEGEEEEDAESDPKV", "length": 424, "header": "tr|A0A8V0ZQR9-1|A0A8V0ZQR9_CHICK Isoform 1 of Nucleosome assembly protein 1 like 4 OS=Gallus gallus OX=9031 GN=NAP1L4 PE=1 SV=1 CANONICAL=A0A8V0ZQR9-1" }, "locus": { "chromosome": "5", "start_pos": 12735196, "end_pos": 12715623, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058819.1", "url": "https://www.ensembl.org/id/ENSGALT00010058819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035784.1", "url": "https://www.ensembl.org/id/ENSGALP00010035784.1" } ] } }, { "isoform_ac": "A0A8V0ZZS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9/entry#A0A8V0ZZS0-1", "sequence": { "sequence": "MADNSSSKAEDTASDSVEAAKNASDKKEKLADQVMQNPQVLAALQERLDNTALTPSSYIETLPKAVKRRIDALKQLQVKCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFINGEAEPTDAESEWHSENEEEEKLAGDLKNVVVIEEKAEAEEINVKGIPDFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSEPGQPMSFSLEFHFGPNDYFSNTVLTKTYKMKSEPDKTDPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNDSFFNFFNPIKVSGDGESLDEDSEFTLAADFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEVRCILHLL", "length": 364, "header": "tr|A0A8V0ZZS0-1|A0A8V0ZQR9_CHICK Computationally mapped isoform of Nucleosome assembly protein 1 like 4 OS=Gallus gallus OX=9031 GN=NAP1L4 PE=1 SV=1 CANONICAL=A0A8V0ZQR9-1" }, "locus": { "chromosome": "5", "start_pos": 12732773, "end_pos": 12719581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058817.1", "url": "https://www.ensembl.org/id/ENSGALT00010058817.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035782.1", "url": "https://www.ensembl.org/id/ENSGALP00010035782.1" } ] } }, { "isoform_ac": "A0A8V1A3D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9/entry#A0A8V1A3D3-1", "sequence": { "sequence": "MADNSSSKAEDTASDSVEAAKNASDKKEKLADQVMQNPQVLAALQERLDNTALTPSSYIETLPKAVKRRIDALKQLQVKCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFINGEAEPTDAESEWHSENEEEEKLAGDLKNVVVIEEKAEAEEINVKGIPDFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSEPGQPMSFSLEFHFGPNDYFSNTVLTKTYKMKSEPDKTDPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNDSFFNFFNPIKVSGDGESLDEDSEFTLAADFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGEEEGEEEEDAESDPKKDSSQPAECKQQ", "length": 387, "header": "tr|A0A8V1A3D3-1|A0A8V0ZQR9_CHICK Computationally mapped isoform of Nucleosome assembly protein 1 like 4 OS=Gallus gallus OX=9031 GN=NAP1L4 PE=1 SV=1 CANONICAL=A0A8V0ZQR9-1" }, "locus": { "chromosome": "5", "start_pos": 12740387, "end_pos": 12719581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058811.1", "url": "https://www.ensembl.org/id/ENSGALT00010058811.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035775.1", "url": "https://www.ensembl.org/id/ENSGALP00010035775.1" } ] } }, { "isoform_ac": "F1P1B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9/entry#F1P1B7-1", "sequence": { "sequence": "MADNSSSKAEDTASDSVEAAKNASDKKEKLADQVMQNPQVLAALQERLDNTALTPSSYIETLPKAVKRRIDALKQLQVKCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFINGEAEPTDAESEWHSENEEEEKLAGDLKNVVVIEEKAEAEEINVKGIPDFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSEPGQPMSFSLEFHFGPNDYFSNTVLTKTYKMKSEPDKTDPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNDSFFNFFNPIKVSGDGESLDEDSEFTLAADFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGEEEGEEEEDAESDPKV", "length": 376, "header": "tr|F1P1B7-1|A0A8V0ZQR9_CHICK Computationally mapped isoform of Nucleosome assembly protein 1 like 4 OS=Gallus gallus OX=9031 GN=NAP1L4 PE=1 SV=1 CANONICAL=A0A8V0ZQR9-1" }, "locus": { "chromosome": "5", "start_pos": 12735196, "end_pos": 12719581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058814.1", "url": "https://www.ensembl.org/id/ENSGALT00010058814.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035779.1", "url": "https://www.ensembl.org/id/ENSGALP00010035779.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 168, "start_aa": "Thr", "end_pos": 168, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr168", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423087", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423087", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A481CQ30-1", "protein_name": "Nucleosome assembly protein 1 like 4", "gene_name": "NAP1L4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADNSFSDGVPSESLEAAKNASNTEKLTDQVMQNPQVLAALQERLDSVSHTPSSYIETLPKAVKRRINALKQLQVKCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESEWHSENEEEDKLAGDVKDKVVIAEKEAAAAEEPNPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSEPGQPMSFVLEFHFEPNDYFSNSVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCAIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPSDSFFNFFSPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDADVNPKV", "length": 375 }, "evidence": [ { "id": "A0A8V0ZQR9", "url": "https://omabrowser.org/oma/group/A0A8V0ZQR9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MEZ2-1", "protein_name": "Nucleosome assembly protein 1-like 4 isoform X1", "gene_name": "Nap1l4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAENSLSDGSPADSVEAAKNASNTEKLTDQVMQNPQVLAALQERLDNVSHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESAWHSENEEEDKLAGDMKNKVVIAEKEAATAEELNPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTNPVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFSPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDEEAEDEDDADVNPKKEPSQPAECKQQ", "length": 386 }, "evidence": [ { "id": "A0A8V0ZQR9", "url": "https://omabrowser.org/oma/group/A0A8V0ZQR9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q55ED1-1", "protein_name": "Nucleosome assembly protein nap1", "gene_name": "nap1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSENNEIEMELPFDSSAITSTEVLDRVNALLTLQDTQNELTEQMEKEILEIEKKYLKKFQPLAEKRFEIVSGKVEPTKEDQQCKAPIQVENLKSVPTDKGIPKFWLHVLQNTEVKDIIEECDIEALEYLVDIKIVQVGDAQDYSLDFHFSENPFFTNTVISKTVKLEEDNELNEIVSTPINWKDGKNFTVQSKKKTVKSKPTKGKAATTTSTTVQEVVPCFFSTFVSPNQDPTSDEEADEIMYIQYQIIAKLKDIVIPEAVNFFLGRASDAEENDYDFGEDFEDEEGEDDDEEDDEEEQTIKKPSGKGKAQPQQPQDCKQQ", "length": 321 }, "evidence": [ { "id": "A0A8V0ZQR9", "url": "https://omabrowser.org/oma/group/A0A8V0ZQR9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5U2Z3-1", "protein_name": "Nucleosome assembly protein 1-like 4", "gene_name": "Nap1l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAENSLSDGGPADSVEAAKNASNTEKLTDQVMQNPQVLAALQERLDNVSHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESAWHSENEEDDKLAGDMKNKVVIAEKEAAAVEELNPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTNPVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFSPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDADVNPKKEPIQPAECKQQ", "length": 386 }, "evidence": [ { "id": "A0A8V0ZQR9", "url": "https://omabrowser.org/oma/group/A0A8V0ZQR9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q78ZA7-1", "protein_name": "Nucleosome assembly protein 1-like 4", "gene_name": "Nap1l4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAENSLSDGGPADSVEAAKNASNTEKLTDQVMQNPQVLAALQERLDNVSHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESAWHSENEEEDKLAGDMKNKVVIAEKEAATVEELNPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTNPVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFSPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDADVNPKV", "length": 375 }, "evidence": [ { "id": "A0A8V0ZQR9", "url": "https://omabrowser.org/oma/group/A0A8V0ZQR9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99733-1", "protein_name": "Nucleosome assembly protein 1-like 4", "gene_name": "NAP1L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADHSFSDGVPSDSVEAAKNASNTEKLTDQVMQNPRVLAALQERLDNVPHTPSSYIETLPKAVKRRINALKQLQVRCAHIEAKFYEEVHDLERKYAALYQPLFDKRREFITGDVEPTDAESEWHSENEEEEKLAGDMKSKVVVTEKAAATAEEPDPKGIPEFWFTIFRNVDMLSELVQEYDEPILKHLQDIKVKFSDPGQPMSFVLEFHFEPNDYFTNSVLTKTYKMKSEPDKADPFSFEGPEIVDCDGCTIDWKKGKNVTVKTIKKKQKHKGRGTVRTITKQVPNESFFNFFNPLKASGDGESLDEDSEFTLASDFEIGHFFRERIVPRAVLYFTGEAIEDDDNFEEGEEGEEEELEGDEEGEDEDDAEINPKV", "length": 375 }, "evidence": [ { "id": "A0A8V0ZQR9", "url": "https://omabrowser.org/oma/group/A0A8V0ZQR9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ZUP3-1", "protein_name": "Nucleosome assembly protein 1;2", "gene_name": "NAP1;2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSNDKDSMNMSDLSTALNEEDRAGLVNALKNKLQNLAGQHSDVLENLTPPVRKRVEFLREIQNQYDEMEAKFFEERAALEAKYQKLYQPLYTKRYEIVNGVVEVEGAAEEVKSEQGEDKSAEEKGVPDFWLIALKNNEITAEEITERDEGALKYLKDIKWSRVEEPKGFKLEFFFDQNPYFKNTVLTKTYHMIDEDEPILEKALGTEIEWYPGKCLTQKILKKKPKKGSKNTKPITKTEDCESFFNFFSPPQVPDDDEDLDDDMADELQGQMEHDYDIGSTIKEKIISHAVSWFTGEAVEADDLDIEDDDDEIDEDDDEEDEEDDEDDEEEDDEDDDEEEEADQGKKSKKKSSAGHKKAGRSQLAEGQAGERPPECKQQ", "length": 379 }, "evidence": [ { "id": "A0A8V0ZQR9", "url": "https://omabrowser.org/oma/group/A0A8V0ZQR9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 168 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 308, "end_pos": 310 }, { "start_pos": 335, "end_pos": 337 }, { "start_pos": 52, "end_pos": 54 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQS1-1", "uniprot_ac": "A0A8V0ZQS1", "uniprot_id": "A0A8V0ZQS1_CHICK", "mass": { "chemical_mass": 33116.0, "monoisotopic_mass": 33116.0 }, "refseq": { "ac": "XP_040503425", "name": "coiled-coil domain-containing protein 70-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503425" }, "gene_names": [ { "name": "LOC121106771", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS1" } ] }, { "name": "LOC121106771", "type": "synonym", "evidence": [ { "id": "XP_040503425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503425" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 70", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS1/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 70-like", "type": "synonym", "evidence": [ { "id": "XP_040503425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503425" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040503425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503425" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC121106771", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS1", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZQS1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQS1", "database": "AlphaFoldDB", "categories": [] }, { "id": "121106771", "url": "https://www.ncbi.nlm.nih.gov/gene/121106771", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IFWDEEM", "url": "https://omabrowser.org/oma/group/IFWDEEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQS1", "url": "https://www.orthodb.org/?gene=A0A8V0ZQS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_040503425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503425", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEIKRSIKIPALYCSRRQSKDFQANLSNFHKEQLYRILKEEQRDFKKEIKAFCKANKNFHEKIRAFQKESKALWKEINTFQENNKAVKEEIKNVLEQSEDFSQKIRVIQMKKNVFQKQVGNIQEKLEEFWNKMKVAEDLIEALGERNKAGQELVKAFLKQNQDIQEQNKAMYEKNKVLQGKNKAMQEKNRASWKDHKVLWKKDKIFWDEEMAISSSKLILWEESIAFKENDWKIQKEKEALGDVVEALHYEKFSLLKNVYILPGEEKLPEREEKGL", "length": 277, "header": "tr|A0A8V0ZQS1-1|A0A8V0ZQS1_CHICK Isoform 1 of Coiled-coil domain-containing protein 70 OS=Gallus gallus OX=9031 GN=LOC121106771 PE=4 SV=1 CANONICAL=A0A8V0ZQS1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS1/entry#A0A8V0ZQS1-1", "sequence": { "sequence": "MVEIKRSIKIPALYCSRRQSKDFQANLSNFHKEQLYRILKEEQRDFKKEIKAFCKANKNFHEKIRAFQKESKALWKEINTFQENNKAVKEEIKNVLEQSEDFSQKIRVIQMKKNVFQKQVGNIQEKLEEFWNKMKVAEDLIEALGERNKAGQELVKAFLKQNQDIQEQNKAMYEKNKVLQGKNKAMQEKNRASWKDHKVLWKKDKIFWDEEMAISSSKLILWEESIAFKENDWKIQKEKEALGDVVEALHYEKFSLLKNVYILPGEEKLPEREEKGL", "length": 277, "header": "tr|A0A8V0ZQS1-1|A0A8V0ZQS1_CHICK Isoform 1 of Coiled-coil domain-containing protein 70 OS=Gallus gallus OX=9031 GN=LOC121106771 PE=4 SV=1 CANONICAL=A0A8V0ZQS1-1" }, "locus": { "chromosome": "14", "start_pos": 9763437, "end_pos": 9762607, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054884.1", "url": "https://www.ensembl.org/id/ENSGALT00010054884.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033182.1", "url": "https://www.ensembl.org/id/ENSGALP00010033182.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQS3-1", "uniprot_ac": "A0A8V0ZQS3", "uniprot_id": "A0A8V0ZQS3_CHICK", "mass": { "chemical_mass": 62642.0, "monoisotopic_mass": 62642.0 }, "refseq": {}, "gene_names": [ { "name": "SOCS7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3" } ] } ], "protein_names": [ { "name": "Suppressor of cytokine signaling 7", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DAB1 and IRS1. Specifically recognizes and binds phosphorylated proteins via its SH2 domain, promoting their ubiquitination. The ECS(SOCS7) complex acts as a key regulator of reelin signaling by mediating ubiquitination and degradation of phosphorylated DAB1 in the cortical plate of the developing cerebral cortex, thereby regulating neuron positioning during cortex development. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Also inhibits prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3#function" }, { "database": "UniProtKB", "id": "ARBA00059017", "url": "https://www.uniprot.org/uniprotkb/ARBA00059017#function" }, { "database": "UniProtKB", "id": "A0A8V0ZVY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SOCS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3", "locus": { "chromosome": "27", "start_pos": 3849489, "end_pos": 3841078, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024122", "url": "https://www.ensembl.org/id/ENSGALG00010024122" } ] } } ], "crossref": [ { "id": "A0A8V0ZQS3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03741", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03741", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10388", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10388", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SHTHIHH", "url": "https://omabrowser.org/oma/group/SHTHIHH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQS3", "url": "https://www.orthodb.org/?gene=A0A8V0ZQS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZVY8", "url": "https://www.orthodb.org/?gene=A0A8V0ZVY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10155:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10155:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVY8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZVY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRAELRDGEAAAAASYRVLSRLLGYGAGPEAGAAGGPGSGAAVAGPPGPGGARLPLPVPAPGGAPRPPPQLMVFRNAAEGRPGEEEAAAGGGEGPAGGPELLCPRHRCALEPKAAAGGGWGPPGGLELQLAALGLRPPALGAKGPAACPCLGPPAAEETSDALLVLEALEPDEAESCSEEEPGSPGPADPQEPPRGAAAAAARRAVPGPGAAGGRKGSLRVRLSRLFRTKSCSGGSAPGDGGGGSRRGAELTASAHSLSDGGGARGRGQEEGRKHRLTRTQSAFSPVVFSPLFTGETVSLVDVDISQRGLSSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVGPMGSSLQSFPLPPPPPPHAPDAFPRVVPLRPTEPAPIQPAPHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPELPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISRQKQDAESST", "length": 592, "header": "tr|A0A8V0ZQS3-1|A0A8V0ZQS3_CHICK Isoform 1 of Suppressor of cytokine signaling 7 OS=Gallus gallus OX=9031 GN=SOCS7 PE=4 SV=1 CANONICAL=A0A8V0ZQS3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3/entry#A0A8V0ZQS3-1", "sequence": { "sequence": "MQRAELRDGEAAAAASYRVLSRLLGYGAGPEAGAAGGPGSGAAVAGPPGPGGARLPLPVPAPGGAPRPPPQLMVFRNAAEGRPGEEEAAAGGGEGPAGGPELLCPRHRCALEPKAAAGGGWGPPGGLELQLAALGLRPPALGAKGPAACPCLGPPAAEETSDALLVLEALEPDEAESCSEEEPGSPGPADPQEPPRGAAAAAARRAVPGPGAAGGRKGSLRVRLSRLFRTKSCSGGSAPGDGGGGSRRGAELTASAHSLSDGGGARGRGQEEGRKHRLTRTQSAFSPVVFSPLFTGETVSLVDVDISQRGLSSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVGPMGSSLQSFPLPPPPPPHAPDAFPRVVPLRPTEPAPIQPAPHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPELPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISRQKQDAESST", "length": 592, "header": "tr|A0A8V0ZQS3-1|A0A8V0ZQS3_CHICK Isoform 1 of Suppressor of cytokine signaling 7 OS=Gallus gallus OX=9031 GN=SOCS7 PE=4 SV=1 CANONICAL=A0A8V0ZQS3-1" }, "locus": { "chromosome": "27", "start_pos": 3849452, "end_pos": 3841190, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058824.1", "url": "https://www.ensembl.org/id/ENSGALT00010058824.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035789.1", "url": "https://www.ensembl.org/id/ENSGALP00010035789.1" } ] } }, { "isoform_ac": "A0A8V0ZVY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3/entry#A0A8V0ZVY8-1", "sequence": { "sequence": "MQRAELRDGEAAAAASYRVLSRLLGYGAGPEAGAAGGPGSGAAVAGPPGPGGARLPLPVPAPGGAPRPPPQLMVFRNAAEGRPGEEEAAAGGGEGPAGGPELLCPRHRCALEPKAAAGGGWGPPGGLELQLAALGLRPPALGAKGPAACPCLGPPAAEETSDALLVLEALEPDEAESCSEEEPGSPGPADPQEPPRGAAAAAARRAVPGPGAAGGRKGSLRVRLSRLFRTKSCSGGSAPGDGGGGSRRGAELTASAHSLSDGGGARGRGQEEGRKHRLTRTQSAFSPVVFSPLFTDDISGTLPTSVLVGPMGSSLQSFPLPPPPPPHAPDAFPRVVPLRPTEPAPIQPAPHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPELPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISRQKQDAESST", "length": 557, "header": "tr|A0A8V0ZVY8-1|A0A8V0ZQS3_CHICK Computationally mapped isoform of Suppressor of cytokine signaling 7 OS=Gallus gallus OX=9031 GN=SOCS7 PE=4 SV=1 CANONICAL=A0A8V0ZQS3-1" }, "locus": { "chromosome": "27", "start_pos": 3849452, "end_pos": 3841190, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058826.1", "url": "https://www.ensembl.org/id/ENSGALT00010058826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035791.1", "url": "https://www.ensembl.org/id/ENSGALP00010035791.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 318, "start_aa": "Thr", "end_pos": 318, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr318", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 512, "start_aa": "Thr", "end_pos": 512, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr512", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K9S1-1", "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "Socs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQGAELRDGEAAAAAASYRVLSRLLGYGEAAPEPGPPPPPPGHGPPPPPFLARPGSRGARPPQLMVFRNVGRPPEEEDAEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPVAGLEAQLAALGLGQPAGPGIKTAGGGCCPCPCPPQPPPPQPPPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGVGGRLLLQPPGPELPPVPFPLQDLVPPGRLSRGEQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGDLAASAASLTDMGGSAVRELDAGRKPRLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRASESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST", "length": 642 }, "evidence": [ { "id": "A0A8V0ZQS3", "url": "https://omabrowser.org/oma/group/A0A8V0ZQS3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BIS1-1", "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "SOCS7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQGAELRDGEAAAAAASYRVLSRLLGYGEAAPEPGPPPPPPGHGPAPPPFLARPGPRGSRPPQLMVFRNVGRPPEEEDAEAAQEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQTPGPELPPVPFPMQDLVPPGRLSRGEQPQQPPPPPPPPGPLRPLAGLSRKGSLKIRLSRLFRTKSCNGGSGGGDGAGKRPSGELVASAASLTDMGGSAGRELDAGRKPRLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVLEPST", "length": 642 }, "evidence": [ { "id": "A0A8V0ZQS3", "url": "https://omabrowser.org/oma/group/A0A8V0ZQS3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F6Q553-1", "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "SOCS7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQGAELRDGEAAAAAASYRVLSRLLGYGEAAPEPGPPPPPPGHGPAPPPFLARPGPRGSRPPQLMVFRNVGRPPEEEDAEAAPDPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQSAGPGVKTVSGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPMQDLVLPGRLSRGEQQQQQQQPPPPPPPPGPLRPLAGPSRKGSLKIRLSRLFRTKSCNGGSGGGDGAGKRPSGELAASAGSLTDMGGSAGRELDTGRKPRLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPTRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEIKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVLEPST", "length": 645 }, "evidence": [ { "id": "A0A8V0ZQS3", "url": "https://omabrowser.org/oma/group/A0A8V0ZQS3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O14512-1", "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "SOCS7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST", "length": 581 }, "evidence": [ { "id": "A0A8V0ZQS3", "url": "https://omabrowser.org/oma/group/A0A8V0ZQS3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VHQ2-1", "protein_name": "Suppressor of cytokine signaling 7", "gene_name": "Socs7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVFRNVGRPPEEEDAEAAREPGPSELLCPRHRCALDPKALPPGLALERTWGPVAGLEAQLAALGLGQPAGPGIKTAGGGCCPCPCPPQPPPPQPPPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGVGGRLLLQPPGPELPPVPFPLQDLVPPGRLSRGEQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGDLAASAASLTDMGGSAVRELDTGRKPRLTRTQSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIAPIRASESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEVYLSLKEAQLISKQKQEVEPST", "length": 579 }, "evidence": [ { "id": "A0A8V0ZQS3", "url": "https://omabrowser.org/oma/group/A0A8V0ZQS3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3" } ], "pmid": "" }, { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling adaptor activity", "id": "GO:0035591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035591", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQS3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 411, "end_pos": 520, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQS3" }, { "id": "PS50225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SOCS box", "eco_id": "ECO_0000259", "start_pos": 515, "end_pos": 565, "start_aa": "Gln", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 318, 512 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQT7-1", "uniprot_ac": "A0A8V0ZQT7", "uniprot_id": "A0A8V0ZQT7_CHICK", "mass": { "chemical_mass": 8755.0, "monoisotopic_mass": 8755.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT7", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZQT7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0ZQT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "AYHQHGHACGQGVEEHRGHGAAVLRAWVRLAVRALVAEEALHVDREGVRVFEIVSQHHGPCHDHHLEVKHAGHTQIATM", "length": 79, "header": "tr|A0A8V0ZQT7-1|A0A8V0ZQT7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZQT7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT7/entry#A0A8V0ZQT7-1", "sequence": { "sequence": "AYHQHGHACGQGVEEHRGHGAAVLRAWVRLAVRALVAEEALHVDREGVRVFEIVSQHHGPCHDHHLEVKHAGHTQIATM", "length": 79, "header": "tr|A0A8V0ZQT7-1|A0A8V0ZQT7_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZQT7-1" }, "locus": { "chromosome": "8", "start_pos": 12051434, "end_pos": 12049941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058839.1", "url": "https://www.ensembl.org/id/ENSGALT00010058839.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035804.1", "url": "https://www.ensembl.org/id/ENSGALP00010035804.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQU7-1", "uniprot_ac": "A0A8V0ZQU7", "uniprot_id": "A0A8V0ZQU7_CHICK", "mass": { "chemical_mass": 58650.0, "monoisotopic_mass": 58650.0 }, "refseq": { "ac": "XP_025007814", "name": "peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007814" }, "gene_names": [ { "name": "PAOX", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] }, { "name": "PAOX", "type": "synonym", "evidence": [ { "id": "XP_025007814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007814" } ] } ], "protein_names": [ { "name": "Peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7/entry#names_and_taxonomy" } ] }, { "name": "1.5.3.13", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7/entry#names_and_taxonomy" } ] }, { "name": "Polyamine oxidase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7/entry#names_and_taxonomy" } ] }, { "name": "peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025007814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007814" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 1, 2022 this sequence version replaced XP_025007814.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025007814", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007814" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PAOX", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7", "locus": { "chromosome": "6", "start_pos": 10097837, "end_pos": 10100617, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022567", "url": "https://www.ensembl.org/id/ENSGALG00010022567" } ] } } ], "crossref": [ { "id": "A0A8V0ZQU7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQU7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000054212", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000054212", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100857693", "url": "https://www.ncbi.nlm.nih.gov/gene/100857693", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100857693", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857693", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GTHSMDE", "url": "https://omabrowser.org/oma/group/GTHSMDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQU7", "url": "https://www.orthodb.org/?gene=A0A8V0ZQU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NJV1", "url": "https://www.orthodb.org/?gene=F1NJV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10742:SF405", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10742:SF405", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01593", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01593", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-141334", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141334", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-351200", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9033241", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025007814", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007814", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25800", "url": "https://www.rhea-db.org/rhea/25800", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25812", "url": "https://www.rhea-db.org/rhea/25812", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "25868", "url": "https://www.rhea-db.org/rhea/25868", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJV1", "url": "https://www.uniprot.org/uniprotkb/F1NJV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NJV1-1", "url": "https://www.uniprot.org/uniprotkb/F1NJV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERGGGGRRVLVVGAGMAALGAAQRLRGPGSVRLLEAGGRVGGRVCSLPFASGLAELGAHWIHGPSEGNPVFRLASSYGLLGPGATEEENQRVEAKGHPLLPVVTYGSSGKVLSPELVNGTRSLFSELLGSAQALVGAEEPPATSVGQYMRAEIARLASGWDEDKDDKRLRLAILSACLKLECCISGTHSMDMVALGSFGEYTSLPGLDCTFPCGYSSLPERILETLPEGTVLLNKPVRTIRWQGSFREEGDTDRDFPVQVECEDGDSFLTDHVIVTVPLGFLKERHQDFFQPPLPERKAEAIRRLGFGTNNKIFLEFEQPFWEPEQQLLEIVWEDESPLAEPSADLEANWFKKLIGFVVLQPPEQLGHVLCGFIAGKESEYMETLSDAEVLSTMTNVLRTLTGNPHLPTPRSVLRSCWHSAPYTRGSYSYVAVGSSGEDIDTLAQPLPEDASDPRVRAWRVIVWDLGRLQGKMGGAVACAQGAQSSVQGHLGPVVWNGETGWENTSSLKLGRCGLQDASQNPLGMGHFPKASGTHSISRYT", "length": 542, "header": "tr|A0A8V0ZQU7-1|A0A8V0ZQU7_CHICK Isoform 1 of Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Gallus gallus OX=9031 GN=PAOX PE=1 SV=1 CANONICAL=A0A8V0ZQU7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7/entry#A0A8V0ZQU7-1", "sequence": { "sequence": "MERGGGGRRVLVVGAGMAALGAAQRLRGPGSVRLLEAGGRVGGRVCSLPFASGLAELGAHWIHGPSEGNPVFRLASSYGLLGPGATEEENQRVEAKGHPLLPVVTYGSSGKVLSPELVNGTRSLFSELLGSAQALVGAEEPPATSVGQYMRAEIARLASGWDEDKDDKRLRLAILSACLKLECCISGTHSMDMVALGSFGEYTSLPGLDCTFPCGYSSLPERILETLPEGTVLLNKPVRTIRWQGSFREEGDTDRDFPVQVECEDGDSFLTDHVIVTVPLGFLKERHQDFFQPPLPERKAEAIRRLGFGTNNKIFLEFEQPFWEPEQQLLEIVWEDESPLAEPSADLEANWFKKLIGFVVLQPPEQLGHVLCGFIAGKESEYMETLSDAEVLSTMTNVLRTLTGNPHLPTPRSVLRSCWHSAPYTRGSYSYVAVGSSGEDIDTLAQPLPEDASDPRVRAWRVIVWDLGRLQGKMGGAVACAQGAQSSVQGHLGPVVWNGETGWENTSSLKLGRCGLQDASQNPLGMGHFPKASGTHSISRYT", "length": 542, "header": "tr|A0A8V0ZQU7-1|A0A8V0ZQU7_CHICK Isoform 1 of Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Gallus gallus OX=9031 GN=PAOX PE=1 SV=1 CANONICAL=A0A8V0ZQU7-1" }, "locus": { "chromosome": "6", "start_pos": 10100418, "end_pos": 10098314, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054927.1", "url": "https://www.ensembl.org/id/ENSGALT00010054927.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033208.1", "url": "https://www.ensembl.org/id/ENSGALP00010033208.1" } ] } }, { "isoform_ac": "F1NJV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7/entry#F1NJV1-1", "sequence": { "sequence": "MERGGGGRRVLVVGAGMAALGAAQRLRGPGSVRLLEAGGRVGGRVCSLPFASGLAELGAHWIHGPSEGNPVFRLASSYGLLGPGATEEENQRVEAKGHPLLPVVTYGSSGKVLSPELVNGTRSLFSELLGSAQALVGAEEPPATSVGQYMRAEIARLASGWDEDKDDKRLRLAILSACLKLECCISGTHSMDMVALGSFGEYTSLPGLDCTFPCGYSSLPERILETLPEGTVLLNKPVRTIRWQGSFREEGDTDRDFPVQVECEDGDSFLTDHVIVTVPLGFLKERHQDFFQPPLPERKAEAIRRLGFGTNNKIFLEFEQPFWEPEQQLLEIVWEDESPLAEPSADLEANWFKKLIGFVVLQPPEQLGHVLCGFIAGKESEYMETLSDAEVLSTMTNVLRTLTGNPHLPTPRSVLRSCWHSAPYTRGSYSYVAVGSSGEDIDTLAQPLPEDASDPRPLQVLFAGEATHRSFYSTTHGALLSGWREAERLNQLPRAAARS", "length": 499, "header": "tr|F1NJV1-1|A0A8V0ZQU7_CHICK Computationally mapped isoform of Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Gallus gallus OX=9031 GN=PAOX PE=1 SV=5 CANONICAL=A0A8V0ZQU7-1" }, "locus": { "chromosome": "6", "start_pos": 10100418, "end_pos": 10098100, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054923.1", "url": "https://www.ensembl.org/id/ENSGALT00010054923.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033206.1", "url": "https://www.ensembl.org/id/ENSGALP00010033206.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:100857693", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857693", "resource": "KEGG Pathway" }, { "id": "R-GGA-141334", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141334", "resource": "Reactome", "description": "PAOs oxidise polyamines to amines" }, { "id": "R-GGA-351200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351200", "resource": "Reactome", "description": "Interconversion of polyamines" }, { "id": "R-GGA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "B8JJQ4-1", "protein_name": "1.5.3.13", "gene_name": "paox", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSMAQRPDRDSQIFIIGCGISGIGAAQKLIKHGFHNVRIIEATARSGGRIRTGRLGDNIIEIGANWIHGPSKENPVFRLACDYQLLDKESMSEENQAIDIGGHPLFVPNWFTSSGRKLGPETMGPALEFFMTLLERSQQFHSTGGEPLPSVGEFIKAEAERLAPEEWKEDRDNFAVRMAMINTLLKLECCVSGTHTMDDVGLGAFGMYTTLPGLDCTFPGGYEGLTDHMMKELPRDIVLYNKPVKCIHWNYTKNGPNTGGTSFPVTIECVNGETFAADHVIVTVPLGYMKKHQNTFLSPSFPLHKLHSIQRMGFGTNNKIFVEFEQPFWDEDCELIYLVWEDETHLTDVVSDLKMSWIRKLTGFTVLKPTERFGHVLCGWIAGQESEYMESLSELEVLQTVTQLLRIFTGNPTIMPRKLLRSQWFHEPYSCGSYSYVAKGCSGYDIDNLAEPLPLKGSNSKPLQVLFAGEATHRSFFSTVHGALLSGWREAERLISHHTSASGSFSSKL", "length": 510 }, "evidence": [ { "id": "A0A8V0ZQU7", "url": "https://omabrowser.org/oma/group/A0A8V0ZQU7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9SU79-1", "protein_name": "Probable polyamine oxidase 5", "gene_name": "PAO5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAKKARIVIIGAGMAGLTAANKLYTSSNNTFELSVVEGGSRIGGRINTSEFSSEKIEMGATWIHGIGGSPVYRIAKETGSLVSDEPWECMDSTIDKAKTFAEGGFEIEPSIVESISGLFTALMELAQGKEISQSDADLSRLAHIYETATRVCSKGSSTSVGSFLKSGFDAYWDSISNGGEEGVKGYGKWSRKSLEEAIFTMFSNTQRTYTSADELSTLDFAAESEYQMFPGEEITIAKGYLSVIHHLASVLPQGVIQLNRKVTKIEWQSNEVKLHFSDGSVVFADHVIVTVSLGVLKAGIETDAELFSPPLPDFKSDAIRRLGYGVVNKLFVEMSQRKFPSLQLVFDREDSEFRFVKIPWWMRRTATITPIHSNSKVLLSWFAGKEALELEKLTDEEIKDAVMTTISCLTGKEVKNDTAKPLTNGSLNDDDEAMKITKVLKSKWGSDPLFRGSYSYVAVGSSGDDLDAMAEPLPKINKKVGQVNGHDQAKVHELQVMFAGEATHRTHYSTTHGAYYSGLREANRLLKHYKCNF", "length": 533 }, "evidence": [ { "id": "A0A8V0ZQU7", "url": "https://omabrowser.org/oma/group/A0A8V0ZQU7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "spermidine catabolic process", "id": "GO:0046203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046203", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ], "pmid": "" }, { "name": "putrescine biosynthetic process", "id": "GO:0009446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009446", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ], "pmid": "" }, { "name": "putrescine catabolic process", "id": "GO:0009447", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009447", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ], "pmid": "" }, { "name": "spermine catabolic process", "id": "GO:0046208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046208", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ], "pmid": "" }, { "name": "positive regulation of spermidine biosynthetic process", "id": "GO:1901307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "polyamine oxidase activity", "id": "GO:0046592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046592", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ], "pmid": "" }, { "name": "N(1)-acetylpolyamine oxidase (3-acetamidopropanal-forming) activity", "id": "GO:0052903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052903", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25800", "name": "", "equation": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPI2-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "25800", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25800" } ] }, { "id": "25812", "name": "", "equation": "N(1)-acetylspermidine + O2 + H2O = 3-acetamidopropanal + putrescine + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPI2-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "25812", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25812" } ] }, { "id": "25868", "name": "", "equation": "N(1),N(12)-diacetylspermine + O2 + H2O = 3-acetamidopropanal + N(1)-acetylspermidine + H2O2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YPI2-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "25868", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25868" } ] }, { "id": "R-GGA-141348", "name": "PAO:FAD oxidises NASPM to PTCN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-141349" ], "output_participant_list": [ "R-ALL-141327", "R-ALL-141350" ], "enzyme_list": [ "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-141348", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141348" } ] }, { "id": "R-GGA-141351", "name": "PAOX:FAD oxidises NASPN to SPM", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-141323" ], "output_participant_list": [ "R-ALL-141324" ], "enzyme_list": [ "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-141351", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-141351" } ] }, { "id": "R-GGA-9033235", "name": "Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033235", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033235" } ] }, { "id": "R-GGA-9033236", "name": "PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XEK2-1", "A0A8V0XIT0-1", "A0A8V1ANC5-1", "E1BRR7-1", "F1N9G6-1", "A0A8V0YMJ0-1", "A0A1D5P3W4-1", "A0A1L1RJ90-1", "A0A8V0Y1Q3-1", "A0A8V0XXY0-1", "A0A8V0Y2T0-1", "A0A8V1AJL7-1", "F1NKY1-1", "A0A8V0ZLD0-1", "A0A8V0ZPK4-1", "A0A8V1A097-1", "A0A8V0YAP6-1", "A0A8V0ZIT7-1", "A0A8V0ZRI7-1", "A0A8V0ZVL2-1", "F1NG68-1", "A0A8V0ZC97-1", "A0A8V1A124-1", "A0A1D5PZB7-1", "A0A8V1A248-1", "A0A8V1A8Z1-1", "Q5ZL13-1", "A0A8V0ZI42-1", "A0A8V0ZQU7-1" ], "evidence": [ { "id": "R-GGA-9033236", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033236" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-141323", "participant_name": "NASPN [peroxisomal matrix]", "crossref": [ { "id": "58101", "database": "ChEBI", "url": "" }, { "id": "ZINC000003870097", "database": "ZINC", "url": "" }, { "id": "HMDB0062644", "database": "HMDB Metabolite", "url": "" }, { "id": "C02567", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-141324", "participant_name": "SPM [peroxisomal matrix]", "crossref": [ { "id": "C00315", "database": "COMPOUND", "url": "" }, { "id": "57834", "database": "ChEBI", "url": "" }, { "id": "ZINC000001532612", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-141327", "participant_name": "3AAPNAL [peroxisomal matrix]", "crossref": [ { "id": "8146179", "database": "PubChem Substance", "url": "" }, { "id": "HMDB0012880", "database": "HMDB Metabolite", "url": "" }, { "id": "ZINC000013542048", "database": "ZINC", "url": "" }, { "id": "30322", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-141349", "participant_name": "NASPM [peroxisomal matrix]", "crossref": [ { "id": "58324", "database": "ChEBI", "url": "" }, { "id": "ZINC000001532698", "database": "ZINC", "url": "" }, { "id": "C00612", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-141350", "participant_name": "PTCN [peroxisomal matrix]", "crossref": [ { "id": "C00134", "database": "COMPOUND", "url": "" }, { "id": "326268", "database": "ChEBI", "url": "" }, { "id": "ZINC000005828633", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5P3W4", "gene_name": "SLC27A2", "activity": [ { "ec_number": "6.2.1.3", "activity": "a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate.", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] }, { "ec_number": "6.2.1.3", "activity": "", "evidence": [ { "id": "A0A1D5P3W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P3W4" } ] } ] }, { "uniprot_ac": "A0A1D5PZB7", "gene_name": "NOS2", "activity": [ { "ec_number": "1.14.13.39", "activity": "2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O.", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] }, { "ec_number": "1.14.13.39", "activity": "", "evidence": [ { "id": "A0A1D5PZB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PZB7" } ] } ] }, { "uniprot_ac": "A0A1L1RJ90", "gene_name": "HMGCL", "activity": [ { "ec_number": "4.1.3.4", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] }, { "ec_number": "4.1.3.4", "activity": "", "evidence": [ { "id": "A0A1L1RJ90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RJ90" } ] } ] }, { "uniprot_ac": "A0A8V0XEK2", "gene_name": "HACL1", "activity": [ { "ec_number": "4.1.2.63", "activity": "2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] }, { "ec_number": "4.1.2.63", "activity": "", "evidence": [ { "id": "A0A8V0XEK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEK2" } ] } ] }, { "uniprot_ac": "A0A8V0XIT0", "gene_name": "CROT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { "id": "A0A8V0XIT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XIT0" } ] } ] }, { "uniprot_ac": "A0A8V0XXY0", "gene_name": "MLYCD", "activity": [ { "ec_number": "4.1.1.9", "activity": "malonyl-CoA + H(+) = acetyl-CoA + CO2.", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] }, { "ec_number": "4.1.1.9", "activity": "", "evidence": [ { "id": "A0A8V0XXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXY0" } ] } ] }, { "uniprot_ac": "A0A8V0Y1Q3", "gene_name": "NUDT7", "activity": [ { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "A0A8V0Y1Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y1Q3" } ] } ] }, { "uniprot_ac": "A0A8V0Y2T0", "gene_name": "ECH1", "activity": [ { "ec_number": "5.3.3.21", "activity": "a (3E,5Z)-dienoyl-CoA = a (2E,4E)-(5,6-saturated)-dienoyl-CoA.", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] }, { "ec_number": "5.3.3.21", "activity": "", "evidence": [ { "id": "A0A8V0Y2T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2T0" } ] } ] }, { "uniprot_ac": "A0A8V0YAP6", "gene_name": "GNPAT", "activity": [ { "ec_number": "2.3.1.42", "activity": "dihydroxyacetone phosphate + an acyl-CoA = a 1-acylglycerone 3-phosphate + CoA.", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] }, { "ec_number": "2.3.1.42", "activity": "", "evidence": [ { "id": "A0A8V0YAP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YAP6" } ] } ] }, { "uniprot_ac": "A0A8V0YMJ0", "gene_name": "ACOT8", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "acetyl-CoA + H2O = acetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "succinyl-CoA + H2O = succinate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "(3S)-3-hydroxy-3-methylglutaryl-CoA + H2O = 3-hydroxy-3-methylglutarate + CoA + H(+).", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.1", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.3", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.11", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.5", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] }, { "ec_number": "3.1.2.27", "activity": "", "evidence": [ { "id": "A0A8V0YMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMJ0" } ] } ] }, { "uniprot_ac": "A0A8V0YPI2", "gene_name": "SMOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0A8V0YPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0A8V0YPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YPI2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC97", "gene_name": "PEX10", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC97" } ] } ] }, { "uniprot_ac": "A0A8V0ZI42", "gene_name": "IDE", "activity": [ { "ec_number": "3.4.24.56", "activity": "Degradation of insulin, glucagon and other polypeptides. No action on proteins.", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] }, { "ec_number": "3.4.24.56", "activity": "", "evidence": [ { "id": "A0A8V0ZI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI42" } ] } ] }, { "uniprot_ac": "A0A8V0ZIT7", "gene_name": "PECR", "activity": [ { "ec_number": "1.3.1.38", "activity": "a (2E)-enoyl-CoA + NADPH + H(+) = a 2,3-saturated acyl-CoA + NADP(+).", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] }, { "ec_number": "1.3.1.38", "activity": "", "evidence": [ { "id": "A0A8V0ZIT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIT7" } ] } ] }, { "uniprot_ac": "A0A8V0ZLD0", "gene_name": "TYSND1", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0A8V0ZLD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLD0" } ] } ] }, { "uniprot_ac": "A0A8V0ZPK4", "gene_name": "IDH1", "activity": [ { "ec_number": "1.1.1.42", "activity": "D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH.", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] }, { "ec_number": "1.1.1.42", "activity": "", "evidence": [ { "id": "A0A8V0ZPK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPK4" } ] } ] }, { "uniprot_ac": "A0A8V0ZQU7", "gene_name": "PAOX", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] }, { "ec_number": "1.5.3.13", "activity": "", "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" } ] } ] }, { "uniprot_ac": "A0A8V0ZRI7", "gene_name": "LONP2", "activity": [ { "ec_number": "3.4.21.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI7" } ] } ] }, { "uniprot_ac": "A0A8V0ZVL2", "gene_name": "CAT", "activity": [ { "ec_number": "1.11.1.6", "activity": "2 H2O2 = O2 + 2 H2O.", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] }, { "ec_number": "1.11.1.6", "activity": "", "evidence": [ { "id": "A0A8V0ZVL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZVL2" } ] } ] }, { "uniprot_ac": "A0A8V1A097", "gene_name": "HAO2", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "A0A8V1A097", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A097" } ] } ] }, { "uniprot_ac": "A0A8V1A124", "gene_name": "AGXT", "activity": [ { "ec_number": "2.6.1.51", "activity": "L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate.", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.44", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] }, { "ec_number": "2.6.1.51", "activity": "", "evidence": [ { "id": "A0A8V1A124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A124" } ] } ] }, { "uniprot_ac": "A0A8V1A248", "gene_name": "EHHADH", "activity": [ { "ec_number": "1.1.1.35", "activity": "a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+).", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "4.2.1.17", "activity": "(3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O.", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "5.3.3.8", "activity": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "5.3.3.8", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "4.2.1.17", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] }, { "ec_number": "1.1.1.35", "activity": "", "evidence": [ { "id": "A0A8V1A248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A248" } ] } ] }, { "uniprot_ac": "A0A8V1A8Z1", "gene_name": "SCP2", "activity": [ { "ec_number": "2.3.1.176", "activity": "4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "tetradecanoyl-CoA + acetyl-CoA = 3-oxohexadecanoyl-CoA + CoA.", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.16", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.155", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] }, { "ec_number": "2.3.1.176", "activity": "", "evidence": [ { "id": "A0A8V1A8Z1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A8Z1" } ] } ] }, { "uniprot_ac": "A0A8V1AJL7", "gene_name": "CRAT", "activity": [ { "ec_number": "2.3.1.137", "activity": "octanoyl-CoA + (R)-carnitine = O-octanoyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.7", "activity": "(R)-carnitine + acetyl-CoA = O-acetyl-(R)-carnitine + CoA.", "evidence": [ { "id": "A0A8V1AJL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJL7" } ] }, { "ec_number": "2.3.1.137", "activity": "", "evidence": [ { 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"evidence": [ { "id": "A0A8V1ANC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ANC5" } ] } ] }, { "uniprot_ac": "E1BRR7", "gene_name": "HAO1", "activity": [ { "ec_number": "1.1.3.15", "activity": "glycolate + O2 = glyoxylate + H2O2.", "evidence": [ { "id": "E1BRR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRR7" } ] }, { "ec_number": "1.1.3.15", "activity": "", "evidence": [ { "id": "E1BRR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BRR7" } ] } ] }, { "uniprot_ac": "F1N9G6", "gene_name": "GSTK1", "activity": [ { "ec_number": "2.5.1.18", "activity": "RX + glutathione = an S-substituted glutathione + a halide anion + H(+).", "evidence": [ { "id": "F1N9G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9G6" } ] }, { "ec_number": "2.5.1.18", "activity": "", "evidence": [ { "id": "F1N9G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1N9G6" } ] } ] }, { "uniprot_ac": "F1NG68", "gene_name": "DECR2", "activity": [ { "ec_number": "1.3.1.124", "activity": "a (2E,4E)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+).", "evidence": [ { "id": "F1NG68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG68" } ] }, { "ec_number": "1.3.1.124", "activity": "", "evidence": [ { "id": "F1NG68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NG68" } ] } ] }, { "uniprot_ac": "F1NKY1", "gene_name": "AMACR", "activity": [ { "ec_number": "5.1.99.4", "activity": "a (2S)-2-methylacyl-CoA = a (2R)-2-methylacyl-CoA.", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ] }, { "ec_number": "5.1.99.4", "activity": "", "evidence": [ { "id": "F1NKY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKY1" } ] } ] }, { "uniprot_ac": "Q5ZL13", "gene_name": "NUDT19", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "CoA + H2O = (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+).", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] }, { "ec_number": "3.6.1.77", "activity": "", "evidence": [ { "id": "Q5ZL13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5ZL13" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQU7" }, { "id": "PF01593", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01593" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amine oxidase", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 456, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.5.3.13", "ec_name": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "1.5.3.13", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.3.13" }, { "id": "1.5.3.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.5.3.13" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 505, "end_pos": 507 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQV0-1", "uniprot_ac": "A0A8V0ZQV0", "uniprot_id": "A0A8V0ZQV0_CHICK", "mass": { "chemical_mass": 38432.0, "monoisotopic_mass": 38432.0 }, "refseq": {}, "gene_names": [ { "name": "VAT1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ] } ], "protein_names": [ { "name": "NADPH:quinone reductase", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0/entry#names_and_taxonomy" } ] }, { "name": "1.6.5.5", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VAT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0", "locus": { "chromosome": "27", "start_pos": 5115329, "end_pos": 5119459, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022460", "url": "https://www.ensembl.org/id/ENSGALG00010022460" } ] } } ], "crossref": [ { "id": "A0A8V0ZQV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08275", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08275", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR002364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQV0", "url": "https://www.orthodb.org/?gene=A0A8V0ZQV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44054", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44054", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44054:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44054:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "14269", "url": "https://www.rhea-db.org/rhea/14269", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSEPAPVAEATPPEQSLEPPVKAASSGEAPEHRALVLTGFGGYEKVKVQTRRSGSPGPGELSVRVRACGLNFADVMMRQGLYDRLPSLPFCPGMECAGTVCTVGEEVRDRQVGDKVMILARTGLWQEVVNVPAVHTFLMPEGMSFEEAAALPVNYITAYMILFDFGNLRPNQSVLIHMAAGGVGTAAIQLCKTVENVTIFGTASASKHDSLKESGVAHPIDYRTMDYVEEVRKISPKGVDIVMDPLGGSDTSKAFHLLKPMGKVITYGVANLITGQKKNLMTMAKTWWNQFSINAIQLLHHNKAVCGYDLGNMDEEYELITGVVLKLINLYNEGKIKPKIDSVWSFDQVSLN", "length": 353, "header": "tr|A0A8V0ZQV0-1|A0A8V0ZQV0_CHICK Isoform 1 of NADPH:quinone reductase OS=Gallus gallus OX=9031 GN=VAT1 PE=1 SV=1 CANONICAL=A0A8V0ZQV0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0/entry#A0A8V0ZQV0-1", "sequence": { "sequence": "MSSEPAPVAEATPPEQSLEPPVKAASSGEAPEHRALVLTGFGGYEKVKVQTRRSGSPGPGELSVRVRACGLNFADVMMRQGLYDRLPSLPFCPGMECAGTVCTVGEEVRDRQVGDKVMILARTGLWQEVVNVPAVHTFLMPEGMSFEEAAALPVNYITAYMILFDFGNLRPNQSVLIHMAAGGVGTAAIQLCKTVENVTIFGTASASKHDSLKESGVAHPIDYRTMDYVEEVRKISPKGVDIVMDPLGGSDTSKAFHLLKPMGKVITYGVANLITGQKKNLMTMAKTWWNQFSINAIQLLHHNKAVCGYDLGNMDEEYELITGVVLKLINLYNEGKIKPKIDSVWSFDQVSLN", "length": 353, "header": "tr|A0A8V0ZQV0-1|A0A8V0ZQV0_CHICK Isoform 1 of NADPH:quinone reductase OS=Gallus gallus OX=9031 GN=VAT1 PE=1 SV=1 CANONICAL=A0A8V0ZQV0-1" }, "locus": { "chromosome": "27", "start_pos": 5119389, "end_pos": 5116333, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054627.1", "url": "https://www.ensembl.org/id/ENSGALT00010054627.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033000.1", "url": "https://www.ensembl.org/id/ENSGALP00010033000.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ], "pmid": "" }, { "name": "NADPH dehydrogenase (quinone) activity", "id": "GO:0008753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008753", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ], "pmid": "" }, { "name": "phospholipid transfer activity", "id": "GO:0120014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120014", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of mitochondrial fusion", "id": "GO:0010637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010637", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ], "pmid": "" }, { "name": "intermembrane phospholipid transfer", "id": "GO:0120010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQV0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14269", "name": "", "equation": "2 a quinone + NADPH + H(+) = 2 a 1,4-benzosemiquinone + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0ZQ45-1", "A0A8V0XPJ0-1", "A0A8V0ZQV0-1" ], "evidence": [ { "id": "14269", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14269" } ] }, { "id": "R-GGA-6798751", "name": "Exocytosis of azurophil granule lumen proteins", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "extracellular region, azurophil granule lumen", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X868-1", "A0A8V0XNR7-1", "A0A8V1AFG6-1", "A2JDL7-1", "F1NI04-1", "F1NML7-1", "F1NQI0-1", "A0A1D5PSE5-1", "P27043-1", "P30374-1", "A0A1D5PN36-1", "A0A1L1RSD2-1", "Q90629-1", "A0A8V0XXM5-1", "A0A8V0ZN26-1", "A0A8V1A4Q4-1", "A0A1D5PM49-1", "A0A8V0YHC8-1", "A0A8V0YL25-1", "A0A8V0YSD2-1", "E1BS94-1", "E1BSN7-1", "A0A8V0YVV2-1", "A0A8V0YW12-1", "A0A8V0Z0Z6-1", "A0A1D5PJC6-1", "A0A8V1AEN9-1", "F1NTQ2-1", "A0A1D5PXN4-1", "P00698-1", "A0A8V0Y6N9-1", "A0A8V0Y726-1", "A0A8V0ZQV0-1" ], "evidence": [ { "id": "R-GGA-6798751", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798751" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5PJC6", "gene_name": "CPPED1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A1D5PJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PJC6" } ] } ] }, { "uniprot_ac": "A0A1D5PM49", "gene_name": "GALNS", "activity": [ { "ec_number": "3.1.6.4", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.", "evidence": [ { "id": "A0A1D5PM49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM49" } ] }, { "ec_number": "3.1.6.4", "activity": "", "evidence": [ { "id": "A0A1D5PM49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM49" } ] } ] }, { "uniprot_ac": "A0A1D5PN36", "gene_name": "LOC107054567", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A1D5PN36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PN36" } ] } ] }, { "uniprot_ac": "A0A1D5PSE5", "gene_name": "ACLY", "activity": [ { "ec_number": "2.3.3.8", "activity": "oxaloacetate + acetyl-CoA + ADP + phosphate = citrate + ATP + CoA.", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] }, { "ec_number": "2.3.3.8", "activity": "", "evidence": [ { "id": "A0A1D5PSE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PSE5" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RSD2", "gene_name": "GUSB", "activity": [ { "ec_number": "3.2.1.31", "activity": "a beta-D-glucuronoside + H2O = D-glucuronate + an alcohol.", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] }, { "ec_number": "3.2.1.31", "activity": "", "evidence": [ { "id": "A0A1L1RSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RSD2" } ] } ] }, { "uniprot_ac": "A0A8V0X868", "gene_name": "GGH", "activity": [ { "ec_number": "3.4.19.9", "activity": "(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate.", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] }, { "ec_number": "3.4.19.9", "activity": "", "evidence": [ { "id": "A0A8V0X868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X868" } ] } ] }, { "uniprot_ac": "A0A8V0XNR7", "gene_name": "CTSC", "activity": [ { "ec_number": "3.4.14.1", "activity": "Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] }, { "ec_number": "3.4.14.1", "activity": "", "evidence": [ { "id": "A0A8V0XNR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNR7" } ] } ] }, { "uniprot_ac": "A0A8V0XPJ0", "gene_name": "VAT1L", "activity": [ { "ec_number": "1.6.5.5", "activity": "2 1,2-naphthoquinone + NADPH + H(+) = 2 1,2-naphthosemiquinone + NADP(+).", "evidence": [ { "id": "A0A8V0XPJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPJ0" } ] }, { "ec_number": "1.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V0XPJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XPJ0" } ] } ] }, { "uniprot_ac": "A0A8V0XXM5", "gene_name": "ARSA", "activity": [ { "ec_number": "3.1.6.8", "activity": "an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + H2O = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + sulfate + H(+).", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] }, { "ec_number": "3.1.6.8", "activity": "", "evidence": [ { "id": "A0A8V0XXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXM5" } ] } ] }, { "uniprot_ac": "A0A8V0Y6N9", "gene_name": "NAPRT", "activity": [ { "ec_number": "6.3.4.21", "activity": "5-phospho-alpha-D-ribose 1-diphosphate + nicotinate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate.", "evidence": [ { "id": "A0A8V0Y6N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6N9" } ] }, { "ec_number": "6.3.4.21", "activity": "", "evidence": [ { "id": "A0A8V0Y6N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y6N9" } ] } ] }, { "uniprot_ac": "A0A8V0Y726", "gene_name": "TXNDC5", "activity": [ { "ec_number": "5.3.4.1", "activity": "Catalyzes the rearrangement of -S-S- bonds in proteins.", "evidence": [ { "id": "A0A8V0Y726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y726" } ] }, { "ec_number": "5.3.4.1", "activity": "", "evidence": [ { "id": "A0A8V0Y726", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y726" } ] } ] }, { "uniprot_ac": "A0A8V0YHC8", "gene_name": "VCP", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8V0YHC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHC8" } ] } ] }, { "uniprot_ac": "A0A8V0YL25", "gene_name": "PRDX6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8V0YL25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL25" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0A8V0YL25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YL25" } ] } ] }, { "uniprot_ac": "A0A8V0YSD2", "gene_name": "FUCA1", "activity": [ { "ec_number": "3.2.1.51", "activity": "an alpha-L-fucoside + H2O = L-fucose + an alcohol.", "evidence": [ { "id": "A0A8V0YSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSD2" } ] }, { "ec_number": "3.2.1.51", "activity": "", "evidence": [ { "id": "A0A8V0YSD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSD2" } ] } ] }, { "uniprot_ac": "A0A8V0YVV2", "gene_name": "GLA", "activity": [ { "ec_number": "3.2.1.-", "activity": "", "evidence": [ { "id": "A0A8V0YVV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVV2" } ] } ] }, { "uniprot_ac": "A0A8V0YW12", "gene_name": "FRK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW12" } ] } ] }, { "uniprot_ac": "A0A8V0Z0Z6", "gene_name": "GLB1", "activity": [ { "ec_number": "3.2.1.23", "activity": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] }, { "ec_number": "3.2.1.23", "activity": "", "evidence": [ { "id": "A0A8V0Z0Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z0Z6" } ] } ] }, { "uniprot_ac": "A0A8V0ZN26", "gene_name": "LOC121106429", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A0A8V0ZN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZN26" } ] } ] }, { "uniprot_ac": "A0A8V0ZQ45", "gene_name": "CRYZ", "activity": [ { "ec_number": "1.6.5.5", "activity": "2 1,2-naphthoquinone + NADPH + H(+) = 2 1,2-naphthosemiquinone + NADP(+).", "evidence": [ { "id": "A0A8V0ZQ45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ45" } ] }, { "ec_number": "1.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V0ZQ45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQ45" } ] } ] }, { "uniprot_ac": "A0A8V0ZQV0", "gene_name": "VAT1", "activity": [ { "ec_number": "1.6.5.5", "activity": "2 1,2-naphthoquinone + NADPH + H(+) = 2 1,2-naphthosemiquinone + NADP(+).", "evidence": [ { "id": "A0A8V0ZQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ] }, { "ec_number": "1.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V0ZQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQV0" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1AEN9", "gene_name": "DPP7", "activity": [ { "ec_number": "3.4.14.2", "activity": "Release of an N-terminal dipeptide, Xaa-Yaa-|-, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides.", "evidence": [ { "id": "A0A8V1AEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ] }, { "ec_number": "3.4.14.2", "activity": "", "evidence": [ { "id": "A0A8V1AEN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEN9" } ] } ] }, { "uniprot_ac": "A0A8V1AFG6", "gene_name": "PTGES2", "activity": [ { "ec_number": "5.3.99.3", "activity": "prostaglandin H2 = prostaglandin E2.", "evidence": [ { "id": "A0A8V1AFG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG6" } ] }, { "ec_number": "5.3.99.3", "activity": "", "evidence": [ { "id": "A0A8V1AFG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFG6" } ] } ] }, { "uniprot_ac": "A2JDL7", "gene_name": "LOC121107389", "activity": [ { "ec_number": "3.4.21.4", "activity": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "A2JDL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2JDL7" } ] }, { "ec_number": "3.4.21.4", "activity": "", "evidence": [ { "id": "A2JDL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2JDL7" } ] } ] }, { "uniprot_ac": "E1BS94", "gene_name": "FUCA2", "activity": [ { "ec_number": "3.2.1.51", "activity": "an alpha-L-fucoside + H2O = L-fucose + an alcohol.", "evidence": [ { "id": "E1BS94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS94" } ] }, { "ec_number": "3.2.1.51", "activity": "", "evidence": [ { "id": "E1BS94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BS94" } ] } ] }, { "uniprot_ac": "E1BSN7", "gene_name": "PYGB", "activity": [ { "ec_number": "2.4.1.1", "activity": "[(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.", "evidence": [ { "id": "E1BSN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSN7" } ] }, { "ec_number": "2.4.1.1", "activity": "", "evidence": [ { "id": "E1BSN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BSN7" } ] } ] }, { "uniprot_ac": "F1NI04", "gene_name": "GNS", "activity": [ { "ec_number": "3.1.6.14", "activity": "Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ] }, { "ec_number": "3.1.6.14", "activity": "", "evidence": [ { "id": "F1NI04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NI04" } ] } ] }, { "uniprot_ac": "F1NML7", "gene_name": "CECR1", "activity": [ { "ec_number": "3.5.4.4", "activity": "2'-deoxyadenosine + H2O + H(+) = 2'-deoxyinosine + NH4(+).", "evidence": [ { "id": "F1NML7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ] }, { "ec_number": "3.5.4.4", "activity": "", "evidence": [ { "id": "F1NML7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NML7" } ] } ] }, { "uniprot_ac": "F1NQI0", "gene_name": "AGA", "activity": [ { "ec_number": "3.5.1.26", "activity": "N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+).", "evidence": [ { "id": "F1NQI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ] }, { "ec_number": "3.5.1.26", "activity": "", "evidence": [ { "id": "F1NQI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NQI0" } ] } ] }, { "uniprot_ac": "F1NTQ2", "gene_name": "HEXB", "activity": [ { "ec_number": "3.2.1.52", "activity": "Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.", "evidence": [ { "id": "F1NTQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NTQ2" } ] }, { "ec_number": "3.2.1.52", "activity": "", "evidence": [ { "id": "F1NTQ2", "database": "UniProtKB", "url": 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"chromosome": "5", "start_pos": 12756503, "end_pos": 12806747, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024139", "url": "https://www.ensembl.org/id/ENSGALG00010024139" } ] } } ], "crossref": [ { "id": "A0A8V0ZQW0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQW0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006454", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006454", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17331", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17331", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423089", "url": "https://www.ncbi.nlm.nih.gov/gene/423089", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423089", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423089", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RLMKYPR", "url": "https://omabrowser.org/oma/group/RLMKYPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQW0", "url": "https://www.orthodb.org/?gene=A0A8V0ZQW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZW17", "url": "https://www.orthodb.org/?gene=A0A8V0ZW17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZY47", "url": "https://www.orthodb.org/?gene=A0A8V0ZY47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BQC0", "url": "https://www.orthodb.org/?gene=E1BQC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24002:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24002:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-549127", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-549127", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZY47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQC0", "url": "https://www.uniprot.org/uniprotkb/E1BQC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BQC0-1", "url": "https://www.uniprot.org/uniprotkb/E1BQC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTMSGKNSPEGEEGAGRMKSESWGQSNAAGDVRRGRVILVAYLIVTLELTFLFMQFGVMPYLAKSLGLDSVGFGYLQTTFGVLQLVGGPIFGRFADQFGNRAALTLSCASASAFFLLLSISTSVPILFLSRLPSVFMHGLPGAQKVITDLTAPSERAAALGKLGLCFGVGIIIGSALGGVISTKFGIFVPMYFGLVGSLINTVLSVVWIPSPSKPKSEHRKTEHSSVFNIREILRVLKFPGVMEIFLVKVLSGFPIGLFLIMFSIISIEFFGLEAVESGYLMSYFGVLQMVVQGLVIGKLTSHCTEQTLLRLGVLVFAGVGLGMALMRTVWHYCIIVVPLVFAFNVLGTITDSILTKAVPSTDTGAMLGICASVQPLTRTVGPTLGVILYKQFGVSSFGYLQLIVNAKIKKETLLYVLWHSCAGGTTLR", "length": 430, "header": "tr|A0A8V0ZQW0-1|A0A8V0ZQW0_CHICK Isoform 1 of Organic cation transporter-like protein 2 OS=Gallus gallus OX=9031 GN=SLC22A18 PE=1 SV=1 CANONICAL=A0A8V0ZQW0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0/entry#A0A8V0ZQW0-1", "sequence": { "sequence": "MSTMSGKNSPEGEEGAGRMKSESWGQSNAAGDVRRGRVILVAYLIVTLELTFLFMQFGVMPYLAKSLGLDSVGFGYLQTTFGVLQLVGGPIFGRFADQFGNRAALTLSCASASAFFLLLSISTSVPILFLSRLPSVFMHGLPGAQKVITDLTAPSERAAALGKLGLCFGVGIIIGSALGGVISTKFGIFVPMYFGLVGSLINTVLSVVWIPSPSKPKSEHRKTEHSSVFNIREILRVLKFPGVMEIFLVKVLSGFPIGLFLIMFSIISIEFFGLEAVESGYLMSYFGVLQMVVQGLVIGKLTSHCTEQTLLRLGVLVFAGVGLGMALMRTVWHYCIIVVPLVFAFNVLGTITDSILTKAVPSTDTGAMLGICASVQPLTRTVGPTLGVILYKQFGVSSFGYLQLIVNAKIKKETLLYVLWHSCAGGTTLR", "length": 430, "header": "tr|A0A8V0ZQW0-1|A0A8V0ZQW0_CHICK Isoform 1 of Organic cation transporter-like protein 2 OS=Gallus gallus OX=9031 GN=SLC22A18 PE=1 SV=1 CANONICAL=A0A8V0ZQW0-1" }, "locus": { "chromosome": "5", "start_pos": 12806451, "end_pos": 12757291, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058865.1", "url": "https://www.ensembl.org/id/ENSGALT00010058865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035830.1", "url": "https://www.ensembl.org/id/ENSGALP00010035830.1" } ] } }, { "isoform_ac": "A0A8V0ZW17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0/entry#A0A8V0ZW17-1", "sequence": { "sequence": "MSTMSGKNSPEGEEGAGRMKSESWGQSNAAGDVRRGRVILVAYLIVTLELTFLFMQFGVMPYLAKSLGLDSVGFGYLQTTFGVLQLVGGPIFGRFADQFGNRAALTLSCASASAFFLLLSISTSVPILFLSRLPSVFMHGLPGAQKVITDLTAPSERAAALGKLGLCFGVGIIIGSALGGVISTKFGIFVPMYFGLVGSLINTVLSVVWIPSPSKPKSEHRKTEHSLFLIMFSIISIEFFGLEAVESGYLMSYFGVLQMVVQGLVIGKLTSHCTEQTLLRLGVLVFAGVGLGMALMRTVWHYCIIVVPLVFAFNVLGTITDSILTKAVPSTDTGAMLGICASVQPLTRTVGPTLGVILYKQFGVSSFGYLQLIVNASLFVYLLKSKSPLRDTKSH", "length": 395, "header": "tr|A0A8V0ZW17-1|A0A8V0ZQW0_CHICK Computationally mapped isoform of Organic cation transporter-like protein 2 OS=Gallus gallus OX=9031 GN=SLC22A18 PE=1 SV=1 CANONICAL=A0A8V0ZQW0-1" }, "locus": { "chromosome": "5", "start_pos": 12806451, "end_pos": 12757392, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058862.1", "url": "https://www.ensembl.org/id/ENSGALT00010058862.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035827.1", "url": "https://www.ensembl.org/id/ENSGALP00010035827.1" } ] } }, { "isoform_ac": "A0A8V0ZY47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0/entry#A0A8V0ZY47-1", "sequence": { "sequence": "MSTMSGKNSPEGEEGAGRMKSESWGQSNAAGDVRRGRVILVAYLIVTLELTFLFMQFGVMPYLAKSLGLDSVGFGYLQTTFGVLQLVGGPIFGRFADQFGNRAALTLSCASASAFFLLLSISTSVPILFLSRLPSVFMHGLPGAQKVITDLTAPSERAAALGKLGLCFGVGIIIGSALGGVISTKFGIFVPMYFGLVGSLINTVLSVVWIPSPSKPKSEHRKTEHSSVFNIREILRVLKFPGVMEIFLVKVLSGFPIGLFLIMFSIISIEFFGLEAVESGYLMSYFGVLQMALMRTVWHYCIIVVPLVFAFNVLGTITDSILTKAVPSTDTGAMLGICASVQPLTRTVGPTLGVILYKQFGVSSFGYLQLIVNASLFVYLLKSKSPLRDTKSH", "length": 393, "header": "tr|A0A8V0ZY47-1|A0A8V0ZQW0_CHICK Computationally mapped isoform of Organic cation transporter-like protein 2 OS=Gallus gallus OX=9031 GN=SLC22A18 PE=1 SV=1 CANONICAL=A0A8V0ZQW0-1" }, "locus": { "chromosome": "5", "start_pos": 12806451, "end_pos": 12757392, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058859.1", "url": "https://www.ensembl.org/id/ENSGALT00010058859.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035824.1", "url": "https://www.ensembl.org/id/ENSGALP00010035824.1" } ] } }, { "isoform_ac": "E1BQC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0/entry#E1BQC0-1", "sequence": { "sequence": "MSTMSGKNSPEGEEGAGRMKSESWGQSNAAGDVRRGRVILVAYLIVTLELTFLFMQFGVMPYLAKSLGLDSVGFGYLQTTFGVLQLVGGPIFGRFADQFGNRAALTLSCASASAFFLLLSISTSVPILFLSRLPSVFMHGLPGAQKVITDLTAPSERAAALGKLGLCFGVGIIIGSALGGVISTKFGIFVPMYFGLVGSLINTVLSVVWIPSPSKPKSEHRKTEHSSVFNIREILRVLKFPGVMEIFLVKVLSGFPIGLFLIMFSIISIEFFGLEAVESGYLMSYFGVLQMVVQGLVIGKLTSHCTEQTLLRLGVLVFAGVGLGMALMRTVWHYCIIVVPLVFAFNVLGTITDSILTKAVPSTDTGAMLGICASVQPLTRTVGPTLGVILYKQFGVSSFGYLQLIVNASLFVYLLKSKSPLRDTKSH", "length": 427, "header": "tr|E1BQC0-1|A0A8V0ZQW0_CHICK Computationally mapped isoform of Organic cation transporter-like protein 2 OS=Gallus gallus OX=9031 GN=SLC22A18 PE=1 SV=4 CANONICAL=A0A8V0ZQW0-1" }, "locus": { "chromosome": "5", "start_pos": 12806451, "end_pos": 12757392, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058869.1", "url": "https://www.ensembl.org/id/ENSGALT00010058869.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035834.1", "url": "https://www.ensembl.org/id/ENSGALP00010035834.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 385, "start_aa": "Thr", "end_pos": 385, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr385", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423089", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423089", "resource": "KEGG Pathway" }, { "id": "R-GGA-549127", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-549127", "resource": "Reactome", "description": "SLC-mediated transport of organic cations" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RYX1-1", "protein_name": "Organic cation transporter-like protein 2", "gene_name": "SLC22A18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MREAGAPRGQGQSPRGTRALSQPQIILLTYVLSALELTCLFMHFSVLPYLSRRLGLDSVAFGYQQTLFGVLQLLGGPVFGRFADQRGARAAFTLSFLASSGLYLLLAAACSPALPGVTLLFASRLPGALMHTLPAAQMVLADLSAPEERPTALSRLGLCFGVGVIFGSLLGGTLSSSCGIQCPVIVALVVSLLGAVLSFTCIPTNTKGASDHAQPVPPGRTKASVFDLKAISRLLLQPGVLPVFLVKVISGFPSGLFTVMFSIISMDFFQLEAAQASYLMSFFGVLQMVIQGLVIGRLSSHFSEGALLRASVLVFSLVGLAMALMTHVFHFCLLMPGLVFSLCTLNVVTDSLLTKAVSASDTGTMLGLCASVQPLMRTLGPTLGGLLYRSFGVPAFGHVQFAVNFLLLLVLWRQPIPRKTDKAP", "length": 424 }, "evidence": [ { "id": "A0A8V0ZQW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q78KK3-1", "protein_name": "Solute carrier family 22 member 18", "gene_name": "Slc67a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALPRQGIIILTYVLAALELTCLFMQFSILPYLSRTLGLDSVSFGYLQTTFGVLQLLGGPVFGRFADQCGARAALSLSFLAASALYLLLVASCSPALPGVFLLFASRIPSALMHTLPAAQMVITDLTAPTERPAALGRLGLCFGIGIIFGSLLGGTLNTAYGIQCPAILAFVVTLLGAVLSFTCVPATTKEASVQSAPQGGTKASVFDLKAITRLLLLPRVLPVFLVKVISGLPSGLFLVMFSIISMDFFQLEAAQAGYLMSFFGILQMMIQGLVIGRLSTHFPEEALLRSSVLVFAVVGLGMALMSSVLHFCFLMPGLVFSLCTLNVVTDSMLTKAVSASDTGTMLGLSASVQPLTRTLGPTLGGLLYRSYGVPIFGHVQLMVNLLVLLVLWKKPLSQKGEKAR", "length": 406 }, "evidence": [ { "id": "A0A8V0ZQW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96BI1-1", "protein_name": "Solute carrier family 67 member A1", "gene_name": "SLC67A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGARAPRDQGRSPGRMSALGRSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDVPRIFLVKVASNCPTGLFMVMFSIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVLLRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTSDTGTMLGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR", "length": 424 }, "evidence": [ { "id": "A0A8V0ZQW0", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "xenobiotic detoxification by transmembrane export across the plasma membrane", "id": "GO:1990961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990961", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW0" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 430, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 385 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQW8-1", "uniprot_ac": "A0A8V0ZQW8", "uniprot_id": "A0A8V0ZQW8_CHICK", "mass": { "chemical_mass": 106074.0, "monoisotopic_mass": 106074.0 }, "refseq": { "ac": "XP_015146512", "name": "putative tyrosine-protein phosphatase auxilin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146512" }, "gene_names": [ { "name": "DNAJC6", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ] }, { "name": "DNAJC6", "type": "synonym", "evidence": [ { "id": "XP_015146512", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146512" } ] } ], "protein_names": [ { "name": "Auxilin", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8/entry#names_and_taxonomy" } ] }, { "name": "DnaJ homolog subfamily C member 6", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8/entry#names_and_taxonomy" } ] }, { "name": "putative tyrosine-protein phosphatase auxilin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015146512", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146512" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015146512.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015146512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146512" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8", "locus": { "chromosome": "8", "start_pos": 28003117, "end_pos": 27963181, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024142", "url": "https://www.ensembl.org/id/ENSGALG00010024142" } ] } } ], "crossref": [ { "id": "A0A8V0ZQW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14563", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14563", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "424698", "url": "https://www.ncbi.nlm.nih.gov/gene/424698", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "XPELDAC", "url": "https://omabrowser.org/oma/group/XPELDAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQW8", "url": "https://www.orthodb.org/?gene=A0A8V0ZQW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQX7", "url": "https://www.orthodb.org/?gene=A0A8V0ZQX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZW27", "url": "https://www.orthodb.org/?gene=A0A8V0ZW27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZW36", "url": "https://www.orthodb.org/?gene=A0A8V0ZW36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23172", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23172", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23172:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23172:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-432722", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015146512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015146512", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQX7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW27", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZW36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZW36-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLLGGYRKKPGGDGYESLQLVESGAEGGGGGPGAVGAGGRSPARQQQQQHRADGSTMDSSGASSPDMESSYGGGLLDMVKGGAGRLFSNLKDNLKDTLKDTSSKVMQSVASYTKGELDISYITSRIIVMSFPAEGVELGFRNHIEDVRTFLDSRHPDHYTVFNLSPKYYRSAKFHNRVSECSWPVRQAPSLHNLYAVCKNMHNWLQQNPKNVCVIHCMDGRAASAVLVSAMFCFCHLFSNPGPAMQLLNTKRPGIVLWPSHRRYIGYICDLIADKPVIPHCKPLTIKSVTLSPVPCFNKQRNGCRPFCDILSGETRILTTSQEYERMKEYRVQEGKVLIPLGATVHGDVVVSVYHMRSTIGGRLQAKMTNTQIFQIQFHTGFIALGTTTLKFTKPELDACDSPDKYPQLFHVILEIEIQSTDRQTELTPPWENFTTKDINPTILFSSHQEHQDTLALAGKGPTDSPQDNIRNVGQSAFFSSLSWQDQKSDKSSSHPTSEDRAALVHEESEQSDDELLSLSSQHSNASGDKPHGTPKHGKKQQELSAPPPPEDVDLLGLDGSPMSKTFPSQPAAAPSNSDLLSDLFGVGGPGSQGQSTQPAADEVFHMAGPGSVQSTPRHSAASASPSPSPRVGEASAFDPFGSSPKQAGPDLLGSFLGSSNVPGDPFLQATRSPSPTVHSDPFHMASSTPTVSIQPDVSGGWDWPNKPGGLGMGSKSAATSPTGSLHSTPTHQPKPQTLDPFADLGTLGASLAGGPSFASKPTTPTGMGGGFPPSPQKPSPQPMGSSWQQGAGYGWQQAQPKAQPGMPHASPQNKPNYNVSFSAMPGAQNERGKGPANADSKPKVSADFEDLLSGQGFNAHKDKKGPKTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVSMADLVTPEQVKKVYRRAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY", "length": 981, "header": "tr|A0A8V0ZQW8-1|A0A8V0ZQW8_CHICK Isoform 1 of Auxilin OS=Gallus gallus OX=9031 GN=DNAJC6 PE=1 SV=1 CANONICAL=A0A8V0ZQW8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8/entry#A0A8V0ZQW8-1", "sequence": { "sequence": "MSLLGGYRKKPGGDGYESLQLVESGAEGGGGGPGAVGAGGRSPARQQQQQHRADGSTMDSSGASSPDMESSYGGGLLDMVKGGAGRLFSNLKDNLKDTLKDTSSKVMQSVASYTKGELDISYITSRIIVMSFPAEGVELGFRNHIEDVRTFLDSRHPDHYTVFNLSPKYYRSAKFHNRVSECSWPVRQAPSLHNLYAVCKNMHNWLQQNPKNVCVIHCMDGRAASAVLVSAMFCFCHLFSNPGPAMQLLNTKRPGIVLWPSHRRYIGYICDLIADKPVIPHCKPLTIKSVTLSPVPCFNKQRNGCRPFCDILSGETRILTTSQEYERMKEYRVQEGKVLIPLGATVHGDVVVSVYHMRSTIGGRLQAKMTNTQIFQIQFHTGFIALGTTTLKFTKPELDACDSPDKYPQLFHVILEIEIQSTDRQTELTPPWENFTTKDINPTILFSSHQEHQDTLALAGKGPTDSPQDNIRNVGQSAFFSSLSWQDQKSDKSSSHPTSEDRAALVHEESEQSDDELLSLSSQHSNASGDKPHGTPKHGKKQQELSAPPPPEDVDLLGLDGSPMSKTFPSQPAAAPSNSDLLSDLFGVGGPGSQGQSTQPAADEVFHMAGPGSVQSTPRHSAASASPSPSPRVGEASAFDPFGSSPKQAGPDLLGSFLGSSNVPGDPFLQATRSPSPTVHSDPFHMASSTPTVSIQPDVSGGWDWPNKPGGLGMGSKSAATSPTGSLHSTPTHQPKPQTLDPFADLGTLGASLAGGPSFASKPTTPTGMGGGFPPSPQKPSPQPMGSSWQQGAGYGWQQAQPKAQPGMPHASPQNKPNYNVSFSAMPGAQNERGKGPANADSKPKVSADFEDLLSGQGFNAHKDKKGPKTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVSMADLVTPEQVKKVYRRAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY", "length": 981, "header": "tr|A0A8V0ZQW8-1|A0A8V0ZQW8_CHICK Isoform 1 of Auxilin OS=Gallus gallus OX=9031 GN=DNAJC6 PE=1 SV=1 CANONICAL=A0A8V0ZQW8-1" }, "locus": { "chromosome": "8", "start_pos": 28000950, "end_pos": 27970618, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058875.1", "url": "https://www.ensembl.org/id/ENSGALT00010058875.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035840.1", "url": "https://www.ensembl.org/id/ENSGALP00010035840.1" } ] } }, { "isoform_ac": "A0A8V0ZQX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8/entry#A0A8V0ZQX7-1", "sequence": { "sequence": "MEPAGGPGASSPDMESSYGGGLLDMVKGGAGRLFSNLKDNLKDTLKDTSSKVMQSVASYTKGELDISYITSRIIVMSFPAEGVELGFRNHIEDVRTFLDSRHPDHYTVFNLSPKYYRSAKFHNRVSECSWPVRQAPSLHNLYAVCKNMHNWLQQNPKNVCVIHCMDGRAASAVLVSAMFCFCHLFSNPGPAMQLLNTKRPGIVLWPSHRRYIGYICDLIADKPVIPHCKPLTIKSVTLSPVPCFNKQRNGCRPFCDILSGETRILTTSQEYERMKEYRVQEGKVLIPLGATVHGDVVVSVYHMRSTIGGRLQAKMTNTQIFQIQFHTGFIALGTTTLKFTKPELDACDSPDKYPQLFHVILEIEIQSTDRQTELTPPWENFTTKDINPTILFSSHQEHQDTLALAGKGPTDSPQDNIRNVGQSAFFSSLSWQDQKSDKSSSHPTSEDRAALVHEESEQSDDELLSLSSQHSNASGDKPHGTPKHGKKQQELSAPPPPEDVDLLGLDGSPMSKTFPSQPAAAPSNSDLLSDLFGVGGPGSQGQSTQPAADEVFHMAGPGSVQSTPRHSAASASPSPSPRVGEASAFDPFGSSPKQAGPDLLGSFLGSSNVPGDPFLQATRSPSPTVHSDPFHMASSTPTVSIQPDVSGGWDWPNKPGGLGMGSKSAATSPTGSLHSTPTHQPKPQTLDPFADLGTLGASLAGGPSFASKPTTPTGMGGGFPPSPQKPSPQPMGSSWQQGAGYGWQQAQPKAQPGMPHASPQNKPNYNVSFSAMPGAQNERGKGPANADSKPKVSADFEDLLSGQGFNAHKDKKGPKTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVSMADLVTPEQVKKVYRRAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY", "length": 927, "header": "tr|A0A8V0ZQX7-1|A0A8V0ZQX7_CHICK Computationally mapped isoform of Auxilin OS=Gallus gallus OX=9031 GN=DNAJC6 PE=1 SV=1 CANONICAL=A0A8V0ZQW8-1" }, "locus": { "chromosome": "8", "start_pos": 28000950, "end_pos": 27963200, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058885.1", "url": "https://www.ensembl.org/id/ENSGALT00010058885.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035850.1", "url": "https://www.ensembl.org/id/ENSGALP00010035850.1" } ] } }, { "isoform_ac": "A0A8V0ZW27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8/entry#A0A8V0ZW27-1", "sequence": { "sequence": "SEGASSPDMESSYGGGLLDMVKGGAGRLFSNLKDNLKDTLKDTSSKVMQSVASYTKGELDISYITSRIIVMSFPAEGVELGFRNHIEDVRTFLDSRHPDHYTVFNLSPKYYRSAKFHNRVSECSWPVRQAPSLHNLYAVCKNMHNWLQQNPKNVCVIHCMDGRAASAVLVSAMFCFCHLFSNPGPAMQLLNTKRPGIVLWPSHRRYIGYICDLIADKPVIPHCKPLTIKSVTLSPVPCFNKQRNGCRPFCDILSGETRILTTSQEYERMKEYRVQEGKVLIPLGATVHGDVVVSVYHMRSTIGGRLQAKMTNTQIFQIQFHTGFIALGTTTLKFTKPELDACDSPDKYPQLFHVILEIEIQSTDRQTELTPPWENFTTKDINPTILFSSHQEHQDTLALAGKGPTDSPQDNIRNVGQSAFFSSLSWQDQKSDKSSSHPTSEDRAALVHEESEQSDDELLSLSSQHSNASGDKPHGTPKHGKKQQELSAPPPPEDVDLLGLDGSPMSKTFPSQPAAAPSNSDLLSDLFGVGGPGSQGQSTQPAADEVFHMAGPGSVQSTPRHSAASASPSPSPRVGEASAFDPFGSSPKQAGPDLLGSFLGSSNVPGDPFLQATRSPSPTVHTSSTPTVSIQPDVSGGWDWPNKPGGLGMGSKSAATSPTGSLHSTPTHQPKPQTLDPFADLGTLGASGPSFASKPTTPTGMGGGFPPSPQKPSPQPMGSSWQQGAGYGWQQAQPKAQPGMPHASPQNKPNYNVSFSAMPGAQNERGKGPANADSKPKVSADFEDLLSGQGFNAHKDKKGPKTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVSMADLVTPEQVKKVYRRAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY", "length": 913, "header": "tr|A0A8V0ZW27-1|A0A8V0ZQW8_CHICK Computationally mapped isoform of Auxilin OS=Gallus gallus OX=9031 GN=DNAJC6 PE=1 SV=1 CANONICAL=A0A8V0ZQW8-1" }, "locus": { "chromosome": "8", "start_pos": 28000950, "end_pos": 27982172, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058873.1", "url": "https://www.ensembl.org/id/ENSGALT00010058873.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035837.1", "url": "https://www.ensembl.org/id/ENSGALP00010035837.1" } ] } }, { "isoform_ac": "A0A8V0ZW36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8/entry#A0A8V0ZW36-1", "sequence": { "sequence": "MDSSVMSFPAEGVELGFRNHIEDVRTFLDSRHPDHYTVFNLSPKYYRSAKFHNRVSECSWPVRQAPSLHNLYAVCKNMHNWLQQNPKNVCVIHCMDGRAASAVLVSAMFCFCHLFSNPGPAMQLLNTKRPGIVLWPSHRRYIGYICDLIADKPVIPHCKPLTIKSVTLSPVPCFNKQRNGCRPFCDILSGETRILTTSQEYERMKEYRVQEGKVLIPLGATVHGDVVVSVYHMRSTIGGRLQAKMTNTQIFQIQFHTGFIALGTTTLKFTKPELDACDSPDKYPQLFHVILEIEIQSTDRQTELTPPWENFTTKDINPTILFSSHQEHQDTLALAGKGPTDSPQDNIRNVGQSAFFSSLSWQDQKSDKSSSHPTSEDRAALVHEESEQSDDELLSLSSQHSNASGDKPHGTPKHGKKQQELSAPPPPEDVDLLGLDGSPMSKTFPSQPAAAPSNSDLLSDLFGVGGPGSQGQSTQPAADEVFHMAGPGSVQSTPRHSAASASPSPSPRVGEASAFDPFGSSPKQAGPDLLGSFLGSSNVPGDPFLQATRSPSPTVHSDPFHMASSTPTVSIQPDVSGGWDWPNKPGGLGMGSKSAATSPTGSLHSTPTHQPKPQTLDPFADLGTLGASLAGGPSFASKPTTPTGMGGGFPPSPQKPSPQPMGSSWQQGAGYGWQQAQPKAQPGMPHASPQNKPNYNVSFSAMPGAQNERGKGPANADSKPKVSADFEDLLSGQGFNAHKDKKGPKTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVSMADLVTPEQVKKVYRRAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY", "length": 857, "header": "tr|A0A8V0ZW36-1|A0A8V0ZQW8_CHICK Computationally mapped isoform of Auxilin OS=Gallus gallus OX=9031 GN=DNAJC6 PE=1 SV=1 CANONICAL=A0A8V0ZQW8-1" }, "locus": { "chromosome": "8", "start_pos": 28000950, "end_pos": 27970789, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058882.1", "url": "https://www.ensembl.org/id/ENSGALT00010058882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035847.1", "url": "https://www.ensembl.org/id/ENSGALP00010035847.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 464, "start_aa": "Thr", "end_pos": 464, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr464", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-432722", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-432722", "resource": "Reactome", "description": "Golgi Associated Vesicle Biogenesis" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LZH5-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKDSENKGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGDLDFTYVTSRIIVMSFPLDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPVPFFNKQRNGCRPYCDVLIGETKIYTTCADFERMKEYRVQDGKIFIPLSITVQGDVVVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDVELQPHDKVMELTPPWEHYCTKDVNPSILFSSHQEHQDTLVLGGQAPIDIPPDNPRHFGQGGFFSTLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHAARKPSKKQQEPAAPAPPEDVDLLGLEGSAVSKNFSSPAAPPSNSELLSDLFGGGGAAGPVQSGQSGVDDVFHPSGPTSTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTASASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGAWDWHTKPGGFGMGSKSAATSPTGSSHGTPTHQNKPQTLDPFADLGTLGGSSFASKPSTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGGYNWQQTQSKPQSSMPHSSPQNRPNYNVSFSSMPGGQNERGKAAANLEGKQKAADFEDLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY", "length": 913 }, "evidence": [ { "id": "A0A8V0ZQW8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A480ZET4-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKDSENKGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGDLDFTYVTSRIIVMSFPLDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAVRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPVPFFNKQRNGCRPYCDVLIGETKIYTTCADFERMKEYRVQDGKIFIPLSITVQGDVVVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDVELQPHDKMIDLTPPWEHYCTKDVNPSILFSSHQEHQDTLVLGGQAPIDIPPDNPRHFGQGGFFSTLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKAHGARKPSKKQQEPAAPPPPEDVDLLGLEGSAVSKNFSSPAAPPTNSELLSDLFGGGGAAGPAQAGQSGVEDVFHPSGPTSTQSTPRRSATSTSASPTLRAGEGAAFDPFGGPSKPSGQDLLGSFLNTGSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVAGGWDWHTKPGGFGMGSKSAATSPTGSSHGTPTHQNKPQTLDPFADLGTLGGSSFASKPSTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGGYNWQQTQSKPQPSMPHASPQHRPNYNVSFSSMPGGQNERGKGSANVEGKQKAADFEDLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRRAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY", "length": 913 }, "evidence": [ { "id": "A0A8V0ZQW8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A6P4-1", "protein_name": "Auxilin", "gene_name": "Dnajc6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGFISGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVSSYTKGDLDFTYVTSRIIVMSFPMDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAVRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKAITVSPIPFFNKQRNGCRPYCDVLIGETKIFSTCTDFERMKEYRVQDGKIFIPLNITVQGDVIVSMYHLRSTIGSRLQAKVTNTQIFQLQFHSGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDIEVQPQDKVIDLTPPWEHYCTKDVNPSILFSSQQEHQDTLALGGQAPADLPPDHPRNLGQGGFFASLCWQDQKSEKSRCEEDHAALVNQESEQSDDELLTLSSPHGNADGDKPHGAKKPGKKQQEPAAPPPPEEVDLLGLEGSDVSTNFSPLAAPPSNSELLSDLFGGGGATGPAQAGQVGVEDVFHPSGPASAQSTPRRATTSASASPTLRVGEGATFDPFGAPAKPPGQDLLGSFLNTSNASSDPFLQPTRSPSPTVHASSTPAVNIQPDIAGGWDWHAKPGGFGMGSKSAATSPTGSTHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQPAGYNWQQAQPKPQSSMPHSSPQNRPNYNVSFSAMPAGQSDRGKGSTNLEGKQKAADFEDLLSSQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRRAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY", "length": 912 }, "evidence": [ { "id": "A0A8V0ZQW8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75061-1", "protein_name": "Auxilin", "gene_name": "DNAJC6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKDSENKGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGDLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVVVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDVELQPHDKVIDLTPPWEHYCTKDVNPSILFSSHQEHQDTLALGGQAPIDIPPDNPRHYGQSGFFASLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGSSNLEGKQKAADFEDLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY", "length": 913 }, "evidence": [ { "id": "A0A8V0ZQW8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80TZ3-1", "protein_name": "Auxilin", "gene_name": "Dnajc6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTNPKSGVAESAGLACSRAAAGENRMKDSENKGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVSSYTKGDLDFTYVTSRIIVMSFPVDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAVRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKAITVSPVPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVIVSMYHLRSTIGSRLQAKVTNTQIFQLQFHSGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDIEVQPQDKVIDLTPPWEHYCTKDVNPSILFSSQQEHQDTLALGGQAPADLPPDHPRNLGQGGFFASLCWQDQKSEKSRCEEDHAALVNQESEQSDDELLTLSSPHGNAEGDKPHGAKKPGKKQQEPAAPPPPEEVDLLGLEGSDVSTNFSSLAAPPSNSELLSDLFGGVGATGPAQAGQAGVEDVFHPSGPVSAQSTPRRTATSASASPTLRVGEGATFDPFGAPAKPPGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDIAGGWDWHTKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQPAGYNWQQTQSKPQSSMPHSSPQNRPNYNVSFSAMPAGQSERGKGSTNLEGKQKAADFEDLLSSQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRRAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY", "length": 938 }, "evidence": [ { "id": "A0A8V0ZQW8", "url": "https://omabrowser.org/oma/group/A0A8V0ZQW8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "pmid": "" }, { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "pmid": "" }, { "name": "extrinsic component of presynaptic endocytic zone membrane", "id": "GO:0098894", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098894", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "pmid": "" }, { "name": "clathrin binding", "id": "GO:0030276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030276", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "clathrin-dependent endocytosis", "id": "GO:0072583", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072583", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "pmid": "" }, { "name": "synaptic vesicle uncoating", "id": "GO:0016191", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016191", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "pmid": "" }, { "name": "regulation of clathrin coat assembly", "id": "GO:1905443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905443", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZQW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" }, { "id": "PS51182", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51182" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 tensin-type", "eco_id": "ECO_0000259", "start_pos": 282, "end_pos": 420, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 917, "end_pos": 981, "start_aa": "Thr", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" }, { "id": "PS51181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatase tensin-type", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 276, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZQW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQW8" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 193, "end_pos": 264, "start_aa": "His", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 464 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 526, "end_pos": 528 }, { "start_pos": 820, "end_pos": 822 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", 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"https://www.uniprot.org/uniprotkb/A0A8V0ZQX3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQX3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC153", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQX3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZQX3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0ZQX3", "url": "https://www.orthodb.org/?gene=A0A8V0ZQX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZQX3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTAPRGSSRGYSLEKLAPQQDGEKSPQAAGVKVAGGQIQLLHLVARAAHDRSQNTALERGHLDRGEVDSPEGADGLRCEALILELVQEEEVVHELRGGQPFAAVPDDSLLHGLGDLKGRQVLDGAAQLLQDGAVAAGQDPTHEDGEELKDFIVSGLIRVPHRALHAQDAGIDLIQDVVIVVILLFEQLLRHGAGDGVPALPAQPREEAREHFEQVEEHRQEAQGEHFGDDAQHHSGIFAHLPDDLRHLLPHFLHQGLLLAQHHVQGSQVLLHRRDGEDKGVLLAWLHARREEEAEDITAEDLQLVELAFRLHLHLKALLQVLLCEAGLPGHHPFVGQLAHRLGHVLHHGDFGGVGAVQHLPAEVEPQEAGVDAAQGLAGRHRSGEVEEMQRGAHQPAVGGQEAGGGDLVLALQVPR", "length": 417, "header": "tr|A0A8V0ZQX3-1|A0A8V0ZQX3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=CCDC153 PE=4 SV=1 CANONICAL=A0A8V0ZQX3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQX3/entry#A0A8V0ZQX3-1", "sequence": { "sequence": "MGTAPRGSSRGYSLEKLAPQQDGEKSPQAAGVKVAGGQIQLLHLVARAAHDRSQNTALERGHLDRGEVDSPEGADGLRCEALILELVQEEEVVHELRGGQPFAAVPDDSLLHGLGDLKGRQVLDGAAQLLQDGAVAAGQDPTHEDGEELKDFIVSGLIRVPHRALHAQDAGIDLIQDVVIVVILLFEQLLRHGAGDGVPALPAQPREEAREHFEQVEEHRQEAQGEHFGDDAQHHSGIFAHLPDDLRHLLPHFLHQGLLLAQHHVQGSQVLLHRRDGEDKGVLLAWLHARREEEAEDITAEDLQLVELAFRLHLHLKALLQVLLCEAGLPGHHPFVGQLAHRLGHVLHHGDFGGVGAVQHLPAEVEPQEAGVDAAQGLAGRHRSGEVEEMQRGAHQPAVGGQEAGGGDLVLALQVPR", "length": 417, "header": "tr|A0A8V0ZQX3-1|A0A8V0ZQX3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN=CCDC153 PE=4 SV=1 CANONICAL=A0A8V0ZQX3-1" }, "locus": { "chromosome": "24", "start_pos": 4324282, "end_pos": 4323032, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058880.1", "url": "https://www.ensembl.org/id/ENSGALT00010058880.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035845.1", "url": "https://www.ensembl.org/id/ENSGALP00010035845.1" } ] } } ], "glycosylation": [], "phosphorylation": [], 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZQY9-1", "uniprot_ac": "A0A8V0ZQY9", "uniprot_id": "A0A8V0ZQY9_CHICK", "mass": { "chemical_mass": 34737.0, "monoisotopic_mass": 34737.0 }, "refseq": { "ac": "XP_004936891", "name": "transmembrane protein 61 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936891" }, "gene_names": [ { "name": "TMEM61", "type": "recommended", "evidence": [ { "id": "A0A8V0ZQY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY9" } ] }, { "name": "TMEM61", "type": "synonym", "evidence": [ { "id": "XP_004936891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936891" } ] } ], "protein_names": [ { "name": "Transmembrane protein 61", "type": "synonym", "evidence": [ { "id": "A0A8V0ZQY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY9/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 61 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004936891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936891" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004936891.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004936891", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936891" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZQY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM61", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY9", "locus": { "chromosome": "8", "start_pos": 24961412, "end_pos": 24956833, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023028", "url": "https://www.ensembl.org/id/ENSGALG00010023028" } ] } } ], "crossref": [ { "id": "A0A8V0ZQY9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZQY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010801", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010801", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "424662", "url": "https://www.ncbi.nlm.nih.gov/gene/424662", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424662", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424662", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZQY9", "url": "https://www.orthodb.org/?gene=A0A8V0ZQY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NM15", "url": "https://www.orthodb.org/?gene=F1NM15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37151:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37151:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15105", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15105", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004936891", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936891", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQY9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZQY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NM15", "url": "https://www.uniprot.org/uniprotkb/F1NM15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NM15-1", "url": "https://www.uniprot.org/uniprotkb/F1NM15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAEHTVCAPCAANFPALLSPRISSLEVDKIRSFFFHYKFISLSVQSAHLINSGSTSRSSCRPWSHARRSTGGPSPVSSRFLAFNGGRELPCITSAPSPPSRANARRMAAASFRYGITITGAVLLVTGTLCFAWWSDGEVGTAVGSGAHLLPPREAQAVPSSSNALLRSVSFFCCGIGGILLLFGLLWSVKANARVVSRRYQYRFPRDLQYFTAEPPEKWNCSSWDATAIPTYEEALTCRPAHGTYLHPVVSKEELTPPPYHDLEEEDDERWQSGRRRSSSDSALFRPSPSWLDTQSPAGPQATPPPSYENISVRGV", "length": 317, "header": "tr|A0A8V0ZQY9-1|A0A8V0ZQY9_CHICK Isoform 1 of Transmembrane protein 61 OS=Gallus gallus OX=9031 GN=TMEM61 PE=4 SV=1 CANONICAL=A0A8V0ZQY9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZQY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY9/entry#A0A8V0ZQY9-1", "sequence": { "sequence": "MRAEHTVCAPCAANFPALLSPRISSLEVDKIRSFFFHYKFISLSVQSAHLINSGSTSRSSCRPWSHARRSTGGPSPVSSRFLAFNGGRELPCITSAPSPPSRANARRMAAASFRYGITITGAVLLVTGTLCFAWWSDGEVGTAVGSGAHLLPPREAQAVPSSSNALLRSVSFFCCGIGGILLLFGLLWSVKANARVVSRRYQYRFPRDLQYFTAEPPEKWNCSSWDATAIPTYEEALTCRPAHGTYLHPVVSKEELTPPPYHDLEEEDDERWQSGRRRSSSDSALFRPSPSWLDTQSPAGPQATPPPSYENISVRGV", "length": 317, "header": "tr|A0A8V0ZQY9-1|A0A8V0ZQY9_CHICK Isoform 1 of Transmembrane protein 61 OS=Gallus gallus OX=9031 GN=TMEM61 PE=4 SV=1 CANONICAL=A0A8V0ZQY9-1" }, "locus": { "chromosome": "8", "start_pos": 24961273, "end_pos": 24957968, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056067.1", "url": "https://www.ensembl.org/id/ENSGALT00010056067.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033920.1", "url": "https://www.ensembl.org/id/ENSGALP00010033920.1" } ] } }, { "isoform_ac": "F1NM15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQY9/entry#F1NM15-1", "sequence": { "sequence": "MAAASFRYGITITGAVLLVTGTLCFAWWSDGEVGTAVGSGAHLLPPREAQAVPSSSNALLRSVSFFCCGIGGILLLFGLLWSVKANARVVSRRYQYRFPRDLQYFTAEPPEKWNCSSWDATAIPTYEEALTCRPAHGTYLHPVVSKEELTPPPYHDLEEEDDERWQSGRRRSSSDSALFRPSPSWLDTQSPAGPQATPPPSYENISVRGV", "length": 210, "header": "tr|F1NM15-1|A0A8V0ZQY9_CHICK Computationally mapped isoform of Transmembrane protein 61 OS=Gallus gallus OX=9031 GN=TMEM61 PE=4 SV=3 CANONICAL=A0A8V0ZQY9-1" }, "locus": { "chromosome": "8", "start_pos": 24961273, "end_pos": 24959121, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056072.1", "url": "https://www.ensembl.org/id/ENSGALT00010056072.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033923.1", "url": "https://www.ensembl.org/id/ENSGALP00010033923.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 304, "start_aa": "Thr", "end_pos": 304, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr304", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424662", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424662", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 311, "end_pos": 313, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 304 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 221, "end_pos": 223 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"https://www.ncbi.nlm.nih.gov/protein/XP_015147447" }, "gene_names": [ { "name": "GLDN", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06" } ] }, { "name": "GLDN", "type": "synonym", "evidence": [ { "id": "XP_015147447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147447" } ] } ], "protein_names": [ { "name": "Gliomedin", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06/entry#names_and_taxonomy" } ] }, { "name": "gliomedin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015147447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147447" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147447.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147447" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLDN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06", "locus": { "chromosome": "10", "start_pos": 9287041, "end_pos": 9270932, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022616", "url": "https://www.ensembl.org/id/ENSGALG00010022616" } ] } } ], "crossref": [ { "id": "A0A8V0ZR06", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR06", "database": "AlphaFoldDB", "categories": [] }, { "id": "427523", "url": "https://www.ncbi.nlm.nih.gov/gene/427523", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427523", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427523", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YIYDHGY", "url": "https://omabrowser.org/oma/group/YIYDHGY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR06", "url": "https://www.orthodb.org/?gene=A0A8V0ZR06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF85", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF85", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015147447", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147447", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEADGRALRCVLAAVGLLSALSAAGTLFLLVQWRELSAALRELEAARIPAANGSVRDPLGSAGPGHPPPARSRRSRRGHVRAESEEMLMMLTYSMVPVRVMVDLCNSTKGICLTGPPGPPGPPGLDGLPGYNGSDGAPGVPGQKGEPGLNGKRGKMGVPGPKGDQGEKGEPGEIGLPGKDGMPGVKGARGAKGEKGDANNDVILEGAKGEPGPPGPPGPPGPPGPPGKRRGKAQLQENVYSNKCTGETCAVPNDDTLAGKAEDRPSDHSKKAECVITSVGSPVHFVSVQQTFGTWMREPANVSDERIWLTMHFSGNSIKEYENSNALLNDTYRIINITGFFYGCGHAVQNNHLYYQKGGTNVILKLGLDKASLGTLLIENALYHGRNYLFSNSKTYFNVAVDEKGLWIIYASSTDETIIVAHIDEETFSIIRHINTTYPKSKAGNAFIACGIMYVTDTKDMTVSFAFDLLKEKQIDARFELRSSQSVLAMLSYSLRDKNLYTWENGSLMVYPVHFGG", "length": 517, "header": "tr|A0A8V0ZR06-1|A0A8V0ZR06_CHICK Isoform 1 of Gliomedin OS=Gallus gallus OX=9031 GN=GLDN PE=4 SV=1 CANONICAL=A0A8V0ZR06-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZR06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06/entry#A0A8V0ZR06-1", "sequence": { "sequence": "MEADGRALRCVLAAVGLLSALSAAGTLFLLVQWRELSAALRELEAARIPAANGSVRDPLGSAGPGHPPPARSRRSRRGHVRAESEEMLMMLTYSMVPVRVMVDLCNSTKGICLTGPPGPPGPPGLDGLPGYNGSDGAPGVPGQKGEPGLNGKRGKMGVPGPKGDQGEKGEPGEIGLPGKDGMPGVKGARGAKGEKGDANNDVILEGAKGEPGPPGPPGPPGPPGPPGKRRGKAQLQENVYSNKCTGETCAVPNDDTLAGKAEDRPSDHSKKAECVITSVGSPVHFVSVQQTFGTWMREPANVSDERIWLTMHFSGNSIKEYENSNALLNDTYRIINITGFFYGCGHAVQNNHLYYQKGGTNVILKLGLDKASLGTLLIENALYHGRNYLFSNSKTYFNVAVDEKGLWIIYASSTDETIIVAHIDEETFSIIRHINTTYPKSKAGNAFIACGIMYVTDTKDMTVSFAFDLLKEKQIDARFELRSSQSVLAMLSYSLRDKNLYTWENGSLMVYPVHFGG", "length": 517, "header": "tr|A0A8V0ZR06-1|A0A8V0ZR06_CHICK Isoform 1 of Gliomedin OS=Gallus gallus OX=9031 GN=GLDN PE=4 SV=1 CANONICAL=A0A8V0ZR06-1" }, "locus": { "chromosome": "10", "start_pos": 9286280, "end_pos": 9270954, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055027.1", "url": "https://www.ensembl.org/id/ENSGALT00010055027.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033270.1", "url": "https://www.ensembl.org/id/ENSGALP00010033270.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427523", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427523", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M0P7-1", "protein_name": "Gliomedin", "gene_name": "GLDN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGGAERGRGGAGWGLRGALAAVALLSALNAAGTVFALCQWRGLSAALRALEEQRGREQREDSALRAFLAELSRAPRRAPAPPLDPASAARNKRSHGGEPAQHIRAESHDMLMMMTYSMVPIRVMVDLCNSTRGICLTGPPGPAGPPGASGLPGHNGSDGQPGPQGPKGEKGANGKRGKMGPPGATGTPGEKGDPGELGLPGSEGQAGQKGDKGDKGDVPNDVLPAGAKGDQGPPGPPGPPGPPGPPGPPGPPGSRRSKGPRQPNMFNGQCPGETCAVPNDDTLVGKTDEKVSEHHSPQAESMITSIGSPIQVLKVKETFGTWIRESANKSDERIWVTEHFSGIRVKEFEDQPSLLNGSYTLIHLPYYFHGCGHTVHNNSLYYHKGGSNTIVRFEFGKETSQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLEERTFSVVQHINTTYPKSKAGNAFIARGILYVTDTKDTRITFAFDLLGGKQINANFALRTSQSVLAMLSYNMRDQHLYSWEDGHLMLYPVQFLSAALHQ", "length": 551 }, "evidence": [ { "id": "A0A8V0ZR06", "url": "https://omabrowser.org/oma/group/A0A8V0ZR06/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RYN3-1", "protein_name": "Gliomedin", "gene_name": "GLDN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGAEQGRRGAEWGLRGALAAVALLSALNAAGTVFALCQWRELSAALRALEVQRGRELREDSALRAFLTELSHAPRQAPAPPPDPAIAARNKRSHGGEPAQHIRTESHDMLMMMTYSMVPIRVMVDLCNSTRGICLTGPPGPAGPPGIGGLPGHNGSDGQPGPQGPKGEKGANGKRGKMGPPGATGTPGEKGDPGELGLTGNEGPVGQKGDKGDKGDVSNDVLPAGAKGDQGPPGPPGPAGPPGPPGPPGPPGSRRSKGPRQPNMFNGQCPGETCAIPNDDTLIGKADEKVSEHHSPQAESLITSIGNPTQVLKVKETFGTWIRESANKSDERIWVTEHFSGIRVKEFEDQPSLLNGSYTLIHLPYYFHGCGHTVYNNSLYYHKGGSNTIVRFEFGKETSQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSMDGSSILVAQLDERTFSVVQHINTTYPKSKAGNAFIAQGILYVTDTKDMRVTFAFDLLAGKQINANFDLRTSQSVLAMLSYNMRDQHLYSWEDGHLMLYPVQFLSAVLNQ", "length": 551 }, "evidence": [ { "id": "A0A8V0ZR06", "url": "https://omabrowser.org/oma/group/A0A8V0ZR06/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6ZMI3-1", "protein_name": "Gliomedin", "gene_name": "GLDN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGAEGGRGDAGWGLRGALAAVALLSALNAAGTVFALCQWRGLSSALRALEAQRGREQREDSALRSFLAELSRAPRGASAPPQDPASSARNKRSHSGEPAPHIRAESHDMLMMMTYSMVPIRVMVDLCNSTKGICLTGPSGPPGPPGAGGLPGHNGLDGQPGPQGPKGEKGANGKRGKMGIPGAAGNPGERGEKGDHGELGLQGNEGPPGQKGEKGDKGDVSNDVLLAGAKGDQGPPGPPGPPGPPGPPGPPGSRRAKGPRQPSMFNGQCPGETCAIPNDDTLVGKADEKASEHHSPQAESMITSIGNPVQVLKVTETFGTWIRESANKSDDRIWVTEHFSGIMVKEFKDQPSLLNGSYTFIHLPYYFHGCGHVVYNNSLYYHKGGSNTLVRFEFGQETSQTLKLENALYFDRKYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLDERTFSVVQHVNTTYPKSKAGNAFIARGILYVTDTKDMRVTFAFDLLGGKQINANFDLRTSQSVLAMLAYNMRDQHLYSWEDGHLMLYPVQFLSTTLNQ", "length": 551 }, "evidence": [ { "id": "A0A8V0ZR06", "url": "https://omabrowser.org/oma/group/A0A8V0ZR06/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BMF8-1", "protein_name": "Gliomedin", "gene_name": "Gldn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRAAERGQGATGWGLRGALVAIALLSALNAAGTVFVLCQWRGLSAALRALEAQRGREQREDSALRAFLAELSRAPGRVPEPSQDPMSAARNKRSHNGEPASHIRAESQDMMMMMTYSMVPIRVMIDLCNSTQGICLTGPPGPPGPPGAGGLPGHNGSDGQPGLQGPKGEKGAIGKRGKMGLPGATGNPGEKGEKGDAGELGLPGNEGPPGQKGDKGDKGDVSNDVLLTGAKGDQGPPGPPGPPGPPGPPGSRRSKGPRPPNVFNSQCPGETCVIPNDDTLVGRADEKANERHSPQTESMITSIGNPAQVLKVRETFGTWMRESANKSDDRIWVTEHFSGIMVKEFKDLPALLNSSFTLLHLPHYFHGCGHAVYNNSLYYHKGGSNTIVRFEFGKETPQTLKLENALYFDRKYLFANSKTYFNIAVDEKGIWIIYASSVDGSSILVAQLDERTFSVTQHINTTYPKSKAGNAFIARGILYVTDTKDTRVTFAFDLLGGKQINANFDFRMSQSVLAMLSYNMRDQHLYSWEDGHLMLYPVQFLSAASSQR", "length": 549 }, "evidence": [ { "id": "A0A8V0ZR06", "url": "https://omabrowser.org/oma/group/A0A8V0ZR06/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein binding involved in heterotypic cell-cell adhesion", "id": "GO:0086080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086080", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZR06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR06" }, { "id": "PS51132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Olfactomedin-like", "eco_id": "ECO_0000259", "start_pos": 273, "end_pos": 517, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 132, "end_pos": 134 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 505, "end_pos": 507 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZR07-1", "uniprot_ac": "A0A8V0ZR07", "uniprot_id": "A0A8V0ZR07_CHICK", "mass": { "chemical_mass": 69373.0, "monoisotopic_mass": 69373.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Major vault protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR07/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR07" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], 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"url": "https://www.ebi.ac.uk/interpro/entry/IPR041139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14165:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14165:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17795", "url": 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"MHMVDLNSSVTRMEVRPHSYIWTMRDPCLVFKQWARESQSHILCGGLCTGTGPIGTVLFDGAGQAQLWHGVTPLQVVLADTALRLRALLGFEDEDGNKFVAGDEWLFEGIYIPHKEVEMVETLQATVIRHNQAIHLWACKECLDCQGTQRVTHSEEWLVKQVGAYLPGVYEEVVDIMDAYVLTDKIQGHETPNATRTFEDAQGHMCHTGEEWLVTQEQSEAYVPDVFKKMVAEVLVTTLAHKIPEVMFLCPHGEKSFLQLGEQLQAGIEDVCVLSEDEGLLLQALQDGTEALALAENEGIYVRDIRTSDVRVLFLQTLWVLSAPKLTPVSLTLLPSVPRNLPQLIPLLPWDRTHAITYQVPHNAAVQVYNYREWRARAVLGPELVVLGPGKQLTVLLCLRLGPDFCADIVTIETADHAGLQLQLAYNWQFEVPEDPKALASCVHGAVAAVTFPQGPLCHLSNSNHLICSAVFSFDEGGWLWEHLRFVPSGLVVTNVNIQSVEPVDQRTHDALQRSVQLAIKITTNSQEAAARSPIPHVTLGVTWSSSCPPSKCPEELSVLLLTFTYMKHFKMHIVMLYMLCLKPQPKRVALPLGIKSQPERLASALGLKATARVREDDTDHEA", "length": 623, "header": "tr|A0A8V0ZR07-1|A0A8V0ZR07_CHICK Isoform 1 of Major vault protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZR07-1" }, "locus": { "chromosome": "24", "start_pos": 6398146, "end_pos": 6390009, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056113.1", "url": "https://www.ensembl.org/id/ENSGALT00010056113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033941.1", "url": "https://www.ensembl.org/id/ENSGALP00010033941.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR07" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR07" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZR07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR07" }, { "id": "PF01505", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01505" }, { "id": "PF17795", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17795" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major vault protein repeat", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 113, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZR07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR07" }, { "id": "PF11978", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11978" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major vault protein shoulder", "eco_id": "ECO_0000259", "start_pos": 402, "end_pos": 434, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"mass": { "chemical_mass": 54015.0, "monoisotopic_mass": 54015.0 }, "refseq": {}, "gene_names": [ { "name": "PLEKHD1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR29" } ] } ], "protein_names": [ { "name": "Pleckstrin homology and coiled-coil domain containing D1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR29/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR29" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PLEKHD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR29", "locus": { "chromosome": "5", "start_pos": 27497459, "end_pos": 27516728, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021543", "url": "https://www.ensembl.org/id/ENSGALG00010021543" } ] } } ], "crossref": [ { "id": "A0A8V0ZR29", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR29", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13281", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13281", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR29", "url": "https://www.orthodb.org/?gene=A0A8V0ZR29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14383", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14383:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14383:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZR29", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR29-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFTSKSSSVSPSPSMEQADSDALDISTKVQLYGVLWKRPFGRQSAKWSRRFFIIKESFLLYYAESEKKSFESNKYFNIHPKGVIPLGGCIVEPKEEPNMPYAIKISHEDFHGNIVLAAESEFEQAQWLEMLQESGKVTWKNAQLGEAMIESLEAQGLQLAKEKQEYVDKLMEETEELCQQREQKEELERLNQVLEAEKQRFEEVVRELRLEQEQIRRELELTARSLNGVEEEKKELRSLTQSLQKNLEELSVEKQQMLEMLETNESPPSTSPSKEQSPSWGLHCSLQQIEEKMQQLLEEKLLAEKRMKENEERSRALEAEREFYSSQSQALQNSLSELTAEKQQTERDLKAEVKVRMELEKRLREAEEALQSLEQGLNSLDRNKEKEEKMKADVSNLRKFFEECIRNAELEAKMPVIMKNSVYIHKAATRRIKSCRLHRRRASASWNDCSEAVPVFHHLTCRS", "length": 463, "header": "tr|A0A8V0ZR29-1|A0A8V0ZR29_CHICK Isoform 1 of Pleckstrin homology and coiled-coil domain containing D1 OS=Gallus gallus OX=9031 GN=PLEKHD1 PE=4 SV=1 CANONICAL=A0A8V0ZR29-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZR29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR29/entry#A0A8V0ZR29-1", "sequence": { "sequence": "MFTSKSSSVSPSPSMEQADSDALDISTKVQLYGVLWKRPFGRQSAKWSRRFFIIKESFLLYYAESEKKSFESNKYFNIHPKGVIPLGGCIVEPKEEPNMPYAIKISHEDFHGNIVLAAESEFEQAQWLEMLQESGKVTWKNAQLGEAMIESLEAQGLQLAKEKQEYVDKLMEETEELCQQREQKEELERLNQVLEAEKQRFEEVVRELRLEQEQIRRELELTARSLNGVEEEKKELRSLTQSLQKNLEELSVEKQQMLEMLETNESPPSTSPSKEQSPSWGLHCSLQQIEEKMQQLLEEKLLAEKRMKENEERSRALEAEREFYSSQSQALQNSLSELTAEKQQTERDLKAEVKVRMELEKRLREAEEALQSLEQGLNSLDRNKEKEEKMKADVSNLRKFFEECIRNAELEAKMPVIMKNSVYIHKAATRRIKSCRLHRRRASASWNDCSEAVPVFHHLTCRS", "length": 463, "header": "tr|A0A8V0ZR29-1|A0A8V0ZR29_CHICK Isoform 1 of Pleckstrin homology and coiled-coil domain containing D1 OS=Gallus gallus OX=9031 GN=PLEKHD1 PE=4 SV=1 CANONICAL=A0A8V0ZR29-1" }, "locus": { "chromosome": "5", "start_pos": 27516140, "end_pos": 27499900, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052246.1", "url": "https://www.ensembl.org/id/ENSGALT00010052246.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031209.1", "url": 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"cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZR35-1", "uniprot_ac": "A0A8V0ZR35", "uniprot_id": "A0A8V0ZR35_CHICK", "mass": { "chemical_mass": 129278.0, "monoisotopic_mass": 129278.0 }, "refseq": { "ac": "NP_989654", "name": "leptin receptor precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" }, "gene_names": [ { "name": "LEPR", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ] }, { "name": "LEPR", "type": "synonym", "evidence": [ { "id": "NP_989654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" } ] }, { "name": "LPR", "type": "synonym", "evidence": [ { "id": "NP_989654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" } ] } ], "protein_names": [ { "name": "Leptin receptor", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35/entry#names_and_taxonomy" } ] }, { "name": "COB-R", "type": "synonym", "evidence": [ { "id": "NP_989654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" } ] }, { "name": "OB receptor", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35/entry#names_and_taxonomy" } ] }, { "name": "leptin receptor precursor", "type": "synonym", "evidence": [ { "id": "NP_989654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AF169827.2, AB033383.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992604, SAMEA103992660 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000239.1. On Oct 4, 2021 this sequence version replaced NP_989654.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" } ] }, { "annotation": "Between 3 and 6 wk of age, leptin receptor expression decreased with age in adipose tissue.", "evidence": [ { "database": "RefSeq", "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" }, { "database": "PubMed", "id": "22560177", "url": "https://glygen.org/publication/PubMed/22560177" } ] }, { "annotation": "In fast growing standard hens fed ad libitum and presenting significant reproductive dysfunction, dramatic up-regulation of granulosa cell expression of the leptin receptor was observed Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" }, { "database": "PubMed", "id": "15473907", "url": "https://glygen.org/publication/PubMed/15473907" } ] }, { "annotation": "LEPR mRNA expressed in chicken tissues is likely to be translated.", "evidence": [ { "database": "RefSeq", "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" }, { "database": "PubMed", "id": "17336982", "url": "https://glygen.org/publication/PubMed/17336982" } ] }, { "annotation": "LEPR was expressed in cerebellum, hypothalamus, cerebrum, adrenal gland, embryonic testis, ovaries, and limb bud. Low level expression was detected in adipose tissue, kidney and heart, whereas no transcripts were found in lung, breast muscle, and liver.", "evidence": [ { "database": "RefSeq", "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" }, { "database": "PubMed", "id": "26587783", "url": "https://glygen.org/publication/PubMed/26587783" } ] }, { "annotation": "Surface plasmon resonance analysis identified six mutants in which leptin binding activity was totally abolished", "evidence": [ { "database": "RefSeq", "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" }, { "database": "PubMed", "id": "15842201", "url": "https://glygen.org/publication/PubMed/15842201" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LEPR", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35", "locus": { "chromosome": "8", "start_pos": 28053564, "end_pos": 28021851, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024165", "url": "https://www.ensembl.org/id/ENSGALG00010024165" } ] } } ], "crossref": [ { "id": "A0A8V0ZR35", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR35", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374223", "url": "https://www.ncbi.nlm.nih.gov/gene/374223", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003529", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003529", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374223", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374223", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPPHCLF", "url": "https://omabrowser.org/oma/group/FPPHCLF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR31", "url": "https://www.orthodb.org/?gene=A0A8V0ZR31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR35", "url": "https://www.orthodb.org/?gene=A0A8V0ZR35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23037:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23037:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06328", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06328", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYHQIILTMSLLLGFLHVAAAHCMVHEIHPRSFTLPCLLLNETSSSPSAAGVVRSWSGWRREHGVAETNPSLLMDEESFLCCLWSNNNASCSLYSANMQARMLIPSEMSISASQERDSNWNIECWVEGKLDLLVCSLQFPKFHMRLDMKVHLLYAVSELSLGDTSTSSLKRTALAAQCNCSEYGKCECHVPSPRLNHTYVMWLKTVIGVTPLWSPLMSVKPIDIVKPEPPLNVRLEMTERGQVKICWSEPVPMPYPLRCEVNISGNSDQNGWQVVQVALNTSLDIDNMLLDSSSFAQVRCKSHCGPGFWSEWSTLYNLNVGAEVLYFPTKILTSVGSNVSFHCIYKNKTQSVASKKIVWWLNLAEEIPESQYTLVNDRVSKVTLFNLKATKPRGSFFYNALYCCHQNRECHHRYAELYVVDVNINIKCETDGYLTKMTCRWSANPNALLLGSSLQLRYHRSKIYCSNFPSTPPESEVKECHFQRNHSYECTFQPVFLLSGYTMWIELKHSLGTLESSPTCVVPADVVKPLPPSSIKAEITRNDGLLNVSWTNPVFTNDDLKFQIRYAVNREELTWELYEVLSVPTRSAVIEVQLCVEYIVQIRCRALDGLGYWSNWSRSAYAAVKDIQAPLHGPEFWRTVTEDPATGQKNVTLLWKPLMKNHSLCSVSRYVIKHQTSENTSWSEYVDNGTTCSFPWTESTHTITILAVNSIGASSVNFNLTLSQQMSTVNAVQSLIAYPVNSTCVILTWTLSPQIYVITSFIIEWRNLNKEEEMKWVQVPPNISKYYIYDHFILIEKYRFSLYPVFAAGVGKSRATDQFSKDGYASQTSSNLYMVLPIVISTSVLLLGALLVSHRRMKKLLWEDVPNPKNCSWAQGVDFQQPETFEHLFVKHPEAMSFEPLLLEPEIVLEDISVTKALEQEDTQDFLVLDSTFTKPEDSEHDSACPSSHFSGRSSLECSPSDPTSGETASQSNIKYATVISNSRSGGLYEQNKNPRCRFDGRFLAEDSLAAGARSGSSWELGNEAFLLLPDQPGSQPCKTLSLISSEGFSEPSDQDDAFTDGGSPERGLHYLGITSLVKRENDIFLTESSRLMCHFHTADLLRGVGFLQNTPPNLNAFIQSSIKAIVPYVPQFQMTAAKVQETTENSC", "length": 1148, "header": "tr|A0A8V0ZR35-1|A0A8V0ZR35_CHICK Isoform 1 of Leptin receptor OS=Gallus gallus OX=9031 GN=LEPR PE=3 SV=1 CANONICAL=A0A8V0ZR35-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZR31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35/entry#A0A8V0ZR31-1", "sequence": { "sequence": "MYHQIILTMSLLLGFLHVAAAHCMVHEIHPRSFTLPCLLLNETSSSPSAAGVVRSWSGWRREHGVAETNPSLLMDEESFLCCLWSNNNASCSLYSANMQARMLIPSEMSISASQERDSNWNIECWVEGKLDLLVCSLQFPKFHMRLDMKVHLLYAVSELSLGDTSTSSLKRTALAAQCNCSEYGKCECHVPSPRLNHTYVMWLKTVIGVTPLWSPLMSVKPIDIVKPEPPLNVRLEMTERGQVKICWSEPVPMPYPLRCEVNISGNSDQNGWQVVQVALNTSLDIDNMLLDSSSFAQVRCKSHCGPGFWSEWSTLYNLNVGAEVLYFPTKILTSVGSNVSFHCIYKNKTQSVASKKIVWWLNLAEEIPESQYTLVNDRVSKVTLFNLKATKPRGSFFYNALYCCHQNRECHHRYAELYVVESEVKECHFQRNHSYECTFQPVFLLSGYTMWIELKHSLGTLESSPTCVVPADVVKPLPPSSIKAEITRNDGLLNVSWTNPVFTNDDLKFQIRYAVNREELTWELYEVLSVPTRSAVIEVQLCVEYIVQIRCRALDGLGYWSNWSRSAYAAVKDIQAPLHGPEFWRTVTEDPATGQKNVTLLWKPLMKNHSLCSVSRYVIKHQTSENTSWSEYVDNGTTCSFPWTESTHTITILAVNSIGASSVNFNLTLSQQMSTVNAVQSLIAYPVNSTCVILTWTLSPQIYVITSFIIEWRNLNKEEEMKWVQVPPNISKYYIYDHFILIEKYRFSLYPVFAAGVGKSRATDQFSKDGYASQTSSNLYMVLPIVISTSVLLLGALLVSHRRMKKLLWEDVPNPKNCSWAQGVDFQQPETFEHLFVKHPEAMSFEPLLLEPEIVLEDISVTKALEQEDTQDFLVLDSTFTKPEDSEHDSACPSSHFSGRSSLECSPSDPTSGETASQSNIKYATVISNSRSGGLYEQNKNPRCRFDGRFLAEDSLAAGARSGSSWELGNEAFLLLPDQPGSQPCKTLSLISSEGFSEPSDQDDAFTDGGSPERGLHYLGITSLVKRENDIFLTESSRLMCHFHTADLLRGVGFLQNTPPNLNAFIQSSIKAIVPYVPQFQMTAAKVQETTENSC", "length": 1095, "header": "tr|A0A8V0ZR31-1|A0A8V0ZR35_CHICK Computationally mapped isoform of Leptin receptor OS=Gallus gallus OX=9031 GN=LEPR PE=3 SV=1 CANONICAL=A0A8V0ZR35-1" }, "locus": { "chromosome": "8", "start_pos": 28052189, "end_pos": 28030114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058942.1", "url": "https://www.ensembl.org/id/ENSGALT00010058942.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035907.1", "url": "https://www.ensembl.org/id/ENSGALP00010035907.1" } ] } }, { "isoform_ac": "A0A8V0ZR35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35/entry#A0A8V0ZR35-1", "sequence": { "sequence": "MYHQIILTMSLLLGFLHVAAAHCMVHEIHPRSFTLPCLLLNETSSSPSAAGVVRSWSGWRREHGVAETNPSLLMDEESFLCCLWSNNNASCSLYSANMQARMLIPSEMSISASQERDSNWNIECWVEGKLDLLVCSLQFPKFHMRLDMKVHLLYAVSELSLGDTSTSSLKRTALAAQCNCSEYGKCECHVPSPRLNHTYVMWLKTVIGVTPLWSPLMSVKPIDIVKPEPPLNVRLEMTERGQVKICWSEPVPMPYPLRCEVNISGNSDQNGWQVVQVALNTSLDIDNMLLDSSSFAQVRCKSHCGPGFWSEWSTLYNLNVGAEVLYFPTKILTSVGSNVSFHCIYKNKTQSVASKKIVWWLNLAEEIPESQYTLVNDRVSKVTLFNLKATKPRGSFFYNALYCCHQNRECHHRYAELYVVDVNINIKCETDGYLTKMTCRWSANPNALLLGSSLQLRYHRSKIYCSNFPSTPPESEVKECHFQRNHSYECTFQPVFLLSGYTMWIELKHSLGTLESSPTCVVPADVVKPLPPSSIKAEITRNDGLLNVSWTNPVFTNDDLKFQIRYAVNREELTWELYEVLSVPTRSAVIEVQLCVEYIVQIRCRALDGLGYWSNWSRSAYAAVKDIQAPLHGPEFWRTVTEDPATGQKNVTLLWKPLMKNHSLCSVSRYVIKHQTSENTSWSEYVDNGTTCSFPWTESTHTITILAVNSIGASSVNFNLTLSQQMSTVNAVQSLIAYPVNSTCVILTWTLSPQIYVITSFIIEWRNLNKEEEMKWVQVPPNISKYYIYDHFILIEKYRFSLYPVFAAGVGKSRATDQFSKDGYASQTSSNLYMVLPIVISTSVLLLGALLVSHRRMKKLLWEDVPNPKNCSWAQGVDFQQPETFEHLFVKHPEAMSFEPLLLEPEIVLEDISVTKALEQEDTQDFLVLDSTFTKPEDSEHDSACPSSHFSGRSSLECSPSDPTSGETASQSNIKYATVISNSRSGGLYEQNKNPRCRFDGRFLAEDSLAAGARSGSSWELGNEAFLLLPDQPGSQPCKTLSLISSEGFSEPSDQDDAFTDGGSPERGLHYLGITSLVKRENDIFLTESSRLMCHFHTADLLRGVGFLQNTPPNLNAFIQSSIKAIVPYVPQFQMTAAKVQETTENSC", "length": 1148, "header": "tr|A0A8V0ZR35-1|A0A8V0ZR35_CHICK Isoform 1 of Leptin receptor OS=Gallus gallus OX=9031 GN=LEPR PE=3 SV=1 CANONICAL=A0A8V0ZR35-1" }, "locus": { "chromosome": "8", "start_pos": 28052189, "end_pos": 28030114, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058947.1", "url": "https://www.ensembl.org/id/ENSGALT00010058947.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035912.1", "url": "https://www.ensembl.org/id/ENSGALP00010035912.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Leptin receptor in the chicken ovary: potential involvement in ovarian dysfunction of ad libitum-fed broiler breeder hens.", "journal": "Reproductive biology and endocrinology : RB&E", "date": "2004-10-08", "authors": "Cassy Sandrine, Metayer Sonia, Crochet Sabine, Rideau Nicole, Collin Anne, Tesseraud Sophie", "evidence": [ { "database": "RefSeq", "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" } ], "reference": [ { "type": "PubMed", "id": "15473907", "url": "https://glygen.org/publication/PubMed/15473907" } ] }, { "title": "Mapping leptin-interacting sites in recombinant leptin-binding domain (LBD) subcloned from chicken leptin receptor.", "journal": "The Biochemical journal", "date": "2005-09-01", "authors": "Niv-Spector L, Raver N, Friedman-Einat M, Grosclaude J, Gussakovsky E E, Livnah O, Gertler A", "evidence": [ { "database": "RefSeq", "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" } ], "reference": [ { "type": "PubMed", "id": "15842201", "url": "https://glygen.org/publication/PubMed/15842201" } ] }, { "title": "Existence of leptin receptor protein in chicken tissues: isolation of a monoclonal antibody against chicken leptin receptor.", "journal": "General and comparative endocrinology", "date": "2007-05-01", "authors": "Ohkubo T, Nishio M, Tsurudome M, Ito M, Ito Y", "evidence": [ { "database": "RefSeq", "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" } ], "reference": [ { "type": "PubMed", "id": "17336982", "url": "https://glygen.org/publication/PubMed/17336982" } ] }, { "title": "Expression of genes for interleukins, neuropeptides, growth hormone receptor, and leptin receptor in adipose tissue from growing broiler chickens.", "journal": "Domestic animal endocrinology", "date": "2012-10", "authors": "Hausman G J, Barb C R, Fairchild B D, Gamble J, Lee-Rutherford L", "evidence": [ { "database": "RefSeq", "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" } ], "reference": [ { "type": "PubMed", "id": "22560177", "url": "https://glygen.org/publication/PubMed/22560177" } ] }, { "title": "Identification of the Long-Sought Leptin in Chicken and Duck: Expression Pattern of the Highly GC-Rich Avian leptin Fits an Autocrine/Paracrine Rather Than Endocrine Function.", "journal": "Endocrinology", "date": "2016-02", "authors": "Seroussi Eyal, Cinnamon Yuval, Yosefi Sara, Genin Olga, Smith Julia Gage, Rafati Nima, Bornel\u00f6v Susanne, Andersson Leif, Friedman-Einat Miriam", "evidence": [ { "database": "RefSeq", "id": "NP_989654", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989654" } ], "reference": [ { "type": "PubMed", "id": "26587783", "url": "https://glygen.org/publication/PubMed/26587783" } ] } ], "pathway": [ { "id": "gga:374223", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374223", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N1E9-1", "protein_name": "Leptin receptor", "gene_name": "LEPR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MICQKSCVALLHWEFIYVITAFNLAYPITPWKFKVSCMPSNTTYDFLFPPGISKNTSNLNGRYEAVVETKLNSSGTYLSNLSSRTTFHCCFWSEEDKNCSVYTDDIEGKAFVTTVNSLVFQQTGANWNIQCWMKEDLKLFICNIESLFKNPFKNYDLKVHLLYVLLDVLEESPLLPQKDSFQVVQCNCSVHECCECHVPVPTAKLNDTLLMYLKITSGGAVFHSPPMSAQPINVVKPDPPLGLRMEITDTGSLKISWSSPTLVPFQLQYQVQYSENSTKYIRKTDEIVSATSLLVDSVLPGSSYGAQVRCKRLDGLGIWSDWSALLTFTTQDVIYFPPKILTAVGSNISFHCIYKNEKKIVSSKKIVWWLNLAEKIPQSQYDVVDDHISKVTFPNLNATKPRGKFTYDAVYCCNEQECHHRYAELYVIDVNINISCETDGYLTKMTCRWSPNAIQSLAGSNLQLRYHRSSLYCSDVPSIHPVSEPKDCHLQRDGFYECIFQPIFLLSGYTMWIRINHTLGSLDSPPACVIPDSVVKPLPPSSVKAEITVKIGLLKISWEKPVFPENNLQFQIRYGLSGKQVQWKMFEVYDAKLKSASLPVPDLCAVYTVQVRCKRLDGLGYWSNWSTPAHTVVMDVKVPIRGPEFWRLISEDTTKKERNVTLLWKPLMKNDSLCSVRRYVVKHHTSHNGTWLEDVGNHTKLTFLWTEQAHSVMVLAINSIGASSANFNLTFSRAISKVNIVQSLSAYPLNSSCVILSWMLSPSDYNLMYFILEWKILNEDSEIKWLRIPSSVKKYYVHDYFIPIEKYQFSLYPIFTEGVGKPKIINSFAQDDEKHQHDADLYVIVPIIISSSILLLGILSVSHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFIKHTESTTFGPLLLEPETISEDISVDTSWKNKDEMVPATTDALLLTTPDLEKGSICISDQCSSAQFSEAESTDITCEDESRRQPSVKYATLLSNSKSGETEEEQGLINSSVSKCFLSNNSPPKDSSSKRSWEIETQAFFILSDQHPNIISPHLPFSEGLDELLKLEGNFPEENNNERPVYYLGVTSIKKRESDVFLTNESRVLSPFPAHCLFTDIRILQDSCSHLVENNFNLGTSGQKTFVSYMPQFQTCSTQTQKIMENKMCDLTV", "length": 1165 }, "evidence": [ { "id": "A0A8V0ZR35", "url": "https://omabrowser.org/oma/group/A0A8V0ZR35/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LFJ6-1", "protein_name": "Leptin receptor", "gene_name": "LEPR", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MICPKFSVALLHWEFIYVITAFDLAYPITPWKFKLSCMPPNTTYDFLLPAGISKNTSTLNGHDEAVVEMELNSSGTYLSNLSSKTTFHCCFWSEEDKNCSVHADNIAGKAFVSAVNSLVFQQTGANWNIQCWMKEDLKLFICYMESLFKNPFKNYDLKVHLLYVLLEVLEGSPLLPQKGSFQSVQCNCSARECCECHVPVSAAKLNYTLLMYLKITSGGAVFHSPLMSVQPINVVKPDPPLGLHMEITDTGNLKISWSSPTLVPFQLQYQVKYSENSTTNMRKADEIVSDTSLLVDSVLPGSSYEVQVRGKRLDGPGIWSDWSTPFTFTTQDVIYFPPKILTSVGSNISFHCIYKNENKIVSSKKIVWWMNLAEKIPQSQYDVVGDHVSKVTFPNMNATKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLTKMTCRWSTNAIQSLVGSTLQLRYHRSSLYCSDVPSVHPISEPKDCQLQRDGFYECIFQPIFLLSGYTMWIRINHPLGSLDSPPTCVIPDSVVKPLPPSSVKAEITAKIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKIYEVYDTKLKSTSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSTPAYTVVTDVKVPIRGPEFWRIINEDATKKERNITLLWKPLMKNDSLCSVRSYVVKHHTSRHGTWSEDVGNHTKLTFLWTEQAHSVTVLAVNSIGASSANFNLTFSWPMSKVNIVQSLSAYPLNSSCVGLSWLLSPSDYNLMYFILEWKILNEDHEIKWLRIPSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDGEKHRNDAGLYVIVPIIISSSILLLGTLLMSHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFIKHTESVTFGPLLLEPETISEDISVDTSWKNKDEMVPPTTVSLLLTTPDLEKSSICISDQRSSAHFSEAESMEITCEDENRRQPSIKYATLLSSPKSGETEQEQELVSSLVSRCFSSSNSLPKESFSNSSWEIETQAFFILSDQHPNMISPHLSFSEGLDELMKFEGNFPKEHNDERSVYYLGVTSIKKRESDVFLTDESRVRCPFPAHCLFADIKILQESCSHLVENNFNLGTSGQKTFVSYMPQFQTCSTQTQKIMENKMYDLTV", "length": 1165 }, "evidence": [ { "id": "A0A8V0ZR35", "url": "https://omabrowser.org/oma/group/A0A8V0ZR35/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P48356-1", "protein_name": "Leptin receptor", "gene_name": "Lepr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMCQKFYVVLLHWEFLYVIAALNLAYPISPWKFKLFCGPPNTTDDSFLSPAGAPNNASALKGASEAIVEAKFNSSGIYVPELSKTVFHCCFGNEQGQNCSALTDNTEGKTLASVVKASVFRQLGVNWDIECWMKGDLTLFICHMEPLPKNPFKNYDSKVHLLYDLPEVIDDSPLPPLKDSFQTVQCNCSLRGCECHVPVPRAKLNYALLMYLEITSAGVSFQSPLMSLQPMLVVKPDPPLGLHMEVTDDGNLKISWDSQTMAPFPLQYQVKYLENSTIVREAAEIVSATSLLVDSVLPGSSYEVQVRSKRLDGSGVWSDWSSPQVFTTQDVVYFPPKILTSVGSNASFHCIYKNENQIISSKQIVWWRNLAEKIPEIQYSIVSDRVSKVTFSNLKATRPRGKFTYDAVYCCNEQACHHRYAELYVIDVNINISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQRDGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVKAEITVNTGLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCAVYVVQVRCRRLDGLGYWSNWSSPAYTLVMDVKVPMRGPEFWRKMDGDVTKKERNVTLLWKPLTKNDSLCSVRRYVVKHRTAHNGTWSEDVGNRTNLTFLWTEPAHTVTVLAVNSLGASLVNFNLTFSWPMSKVSAVESLSAYPLSSSCVILSWTLSPDDYSLLYLVIEWKILNEDDGMKWLRIPSNVKKFYIHDNFIPIEKYQFSLYPVFMEGVGKPKIINGFTKDAIDKQQNDAGLYVIVPIIISSCVLLLGTLLISHQRMKKLFWDDVPNPKNCSWAQGLNFQKPETFEHLFTKHAESVIFGPLLLEPEPISEEISVDTAWKNKDEMVPAAMVSLLLTTPDPESSSICISDQCNSANFSGSQSTQVTCEDECQRQPSVKYATLVSNDKLVETDEEQGFIHSPVSNCISSNHSPLRQSFSSSSWETEAQTFFLLSDQQPTMISPQLSFSGLDELLELEGSFPEENHREKSVCYLGVTSVNRRESGVLLTGEAGILCTFPAQCLFSDIRILQERCSHFVENNLSLGTSGENFVPYMPQFQTCSTHSHKIMENKMCDLTV", "length": 1162 }, "evidence": [ { "id": "A0A8V0ZR35", "url": "https://omabrowser.org/oma/group/A0A8V0ZR35/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48357-1", "protein_name": "Leptin receptor", "gene_name": "LEPR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNSNGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVFQQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGSFQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNEDGEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDAGLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFIKHTASVTCGPLLLEPETISEDISVDTSWKNKDEMMPTTVVSLLSTTDLEKGSVCISDQFNSVNFSEAEGTEVTYEDESQRQPFVKYATLISNSKPSETGEEQGLINSSVTKCFSSKNSPLKDSFSNSSWEIEAQAFFILSDQHPNIISPHLTFSEGLDELLKLEGNFPEENNDKKSIYYLGVTSIKKRESGVLLTDKSRVSCPFPAPCLFTDIRVLQDSCSHFVENNINLGTSSKKTFASYMPQFQTCSTQTHKIMENKMCDLTV", "length": 1165 }, "evidence": [ { "id": "A0A8V0ZR35", "url": "https://omabrowser.org/oma/group/A0A8V0ZR35/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62959-1", "protein_name": "Leptin receptor", "gene_name": "Lepr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTCQKFYVVLLHWEFLYVITALNLAYPTSPWRFKLFCAPPSTTDDSFLSPAGVPNNTSSLKGASEALVEAKFNSTGIYVSELSKTIFHCCFGNEQGQNCSALTGNTEGKTLASVVKPLVFRQLGVNWDIECWMKGDLTLFICHMEPLLKNPFKNYDSKVHLLYDLPEVIDDLPLPPLKDSFQTVQCNCSVRECECHVPVPRAKVNYALLMYLEITSAGVSFQSPLMSLQPMLVVKPDPPLGLRMEVTDDGNLKISWDSQTKAPFPLQYQVKYLENSTIVREAAEIVSDTSLLVDSVLPGSSYEVQVRSKRLDGSGVWSDWSLPQLFTTQDVMYFPPKILTSVGSNASFCCIYKNENQTISSKQIVWWMNLAEKIPETQYNTVSDHISKVTFSNLKATRPRGKFTYDAVYCCNEQACHHRYAELYVIDVNINISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDNPSIRPTSELKNCVLQTDGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVKAEITINTGLLKVSWEKPVFPENNLQFQIRYGLNGKEIQWKTHEVFDAKSKSASLPVSDLCAVYVVQVRCRRLDGLGYWSNWSSPAYTLVMDVKVPMRGPEFWRIMDGDITKKERNVTLLWKPLMKNDSLCSVRRYVVKHRTAHNGTWSQDVGNQTNLTFLWAESAHTVTVLAINSIGASLVNFNLTFSWPMSKVNAVQSLSAYPLSSSCVILSWTLSPNDYSLLYLVIEWKNLNDDDGMKWLRIPSNVNKYYIHDNFIPIEKYQFSLYPVFMEGVGKPKIINGFTKDDIAKQQNDAGLYVIVPIIISSCVLLLGTLLISHQRMKKLFWDDVPNPKNCSWAQGLNFQKPETFEHLFTKHAESVIFGPLLLEPEPVSEEISVDTAWKNKDEMVPAAMVSLLLTTPDSTRGSICISDQCNSANFSGAQSTQGTCEDECQSQPSVKYATLVSNVKTVETDEEQGAIHSSVSQCIARKHSPLRQSFSSNSWEIEAQAFFLLSDHPPNVISPQLSFSGLDELLELEGNFPEENHGEKSVYYLGVSSGNKRENDMLLTDEAGVLCPFPAHCLFSDIRILQESCSHFVENNLNLGTSGKNFVPYMPQFQSCSTHSHKIIENKMCDLTV", "length": 1162 }, "evidence": [ { "id": "A0A8V0ZR35", "url": "https://omabrowser.org/oma/group/A0A8V0ZR35/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cytokine receptor activity", "id": "GO:0004896", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004896", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "leptin receptor activity", "id": "GO:0038021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "energy homeostasis", "id": "GO:0097009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097009", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "negative regulation of autophagy", "id": "GO:0010507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010507", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "regulation of feeding behavior", "id": "GO:0060259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "cytokine-mediated signaling pathway", "id": "GO:0019221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019221", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "T cell differentiation", "id": "GO:0030217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030217", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "regulation of transport", "id": "GO:0051049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051049", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "positive regulation of cold-induced thermogenesis", "id": "GO:0120162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "regulation of bone remodeling", "id": "GO:0046850", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046850", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "bone growth", "id": "GO:0098868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via STAT", "id": "GO:0097696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097696", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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SV=1 CANONICAL=A0A8V0ZR67-1" }, "locus": { "chromosome": "11", "start_pos": 6950446, "end_pos": 6933832, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058984.1", "url": "https://www.ensembl.org/id/ENSGALT00010058984.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035949.1", "url": "https://www.ensembl.org/id/ENSGALP00010035949.1" } ] } }, { "isoform_ac": "A0A8V0ZWC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR67/entry#A0A8V0ZWC1-1", "sequence": { "sequence": "MLPDQKEYIKGLCEPELEEKEYYPKDMHCIFVGAQNMFLNSLIQDTCADITVLEIGLLSIKGGAEAVVMAQSQVQQFVKLFENNESLSSECESDIKKQFRQFVEAHADKYTMDLLILPSSLKRELLTLMQTECCESRGAIIDLTGSKSPAELLQDKTSKVILTSRDGKMGDEEERNNAGTPVTELTKQMDNVFSDAPETSFVPINVVPPLEAMTSKERQSCKRRFSDAEESLPKKQLSLENDQEVKSVSHNDSSKRDAVIDLISDSSGELDDPSYCIKEGDDISEEIEYKILVNFFRTMGYSQSIVEKVIGVLGQSVEPLTLLEEIEKENLRFQKEQEWSSKTPKTTNLRLGSNANSSHKLEDEDISCKKNPLKTTHTSNETRTERHKARDMPSTQVDAEDKMHVSVCKPVSPGKSSAICYKKTDIYCPGKNHNSTSSDAETDGFVPLSPPQAGAPKDVDFVARGSSDVRCTSAKSKTAVHQKSAGPSPVQNSHSVVEDQLGHCSSYQVRSPNQHTSQMSNFENPTQAHVLSSEIHSANPDREVSGSHRRHIDPSITGVQRFLESLKKPYRLELKNEPGKPYLKHIIIDGSNVAISHGLRKFFSCRGIAIAVDYFWKRGHRNITVFVPQWRTRRDPSITEQDFLTQLEDVGILSLTPSRMVLGARIASHDDRFLLHLADKTGGVIVTNDNFREFVTESLAWREIIQKRLLQYTFAGDIFMVPDDPLGRNGPRLDDFLQSEGCSRDFLSAQKALQSREQYSSETPLFMHVPNPASSSQQPKNRAHGDHSAAWLPLDTNMKACLSIPPQRSASETVWLREALIKIFPDYEQRQKIDKILADHPFMRDLNALSAMVLD", "length": 855, "header": "tr|A0A8V0ZWC1-1|A0A8V0ZR67_CHICK Computationally mapped isoform of NEDD4-binding protein 1 OS=Gallus gallus OX=9031 GN=N4BP1 PE=3 SV=1 CANONICAL=A0A8V0ZR67-1" }, "locus": { "chromosome": "11", "start_pos": 6950446, "end_pos": 6935866, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010058976.1", "url": "https://www.ensembl.org/id/ENSGALT00010058976.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010035941.1", "url": "https://www.ensembl.org/id/ENSGALP00010035941.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9758274", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9758274", "resource": "Reactome", "description": "Regulation of NF-kappa B signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR67", "url": 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"A0A8V0ZR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR67" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR67" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR67" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR67" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR67" } ], "pmid": "" }, { "name": "negative regulation of viral genome replication", "id": "GO:0045071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045071", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR67" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR67" } ], "pmid": "" }, { "name": "cellular response to UV", "id": "GO:0034644", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034644", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR67" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZR75-1", "uniprot_ac": "A0A8V0ZR75", "uniprot_id": "A0A8V0ZR75_CHICK", "mass": { "chemical_mass": 86210.0, "monoisotopic_mass": 86210.0 }, "refseq": { "ac": "XP_025001443", "name": "cyclin-T1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001443" }, "gene_names": [ { "name": "CCNT1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZR75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ] }, { "name": "CCNT1", "type": "synonym", "evidence": [ { "id": "XP_025001443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001443" } ] } ], "protein_names": [ { "name": "Cyclin T1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZR75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75/entry#names_and_taxonomy" } ] }, { "name": "cyclin-T1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025001443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001443" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025001443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001443" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCNT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75", "locus": { "chromosome": "34", "start_pos": 91649, "end_pos": 83265, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023074", "url": "https://www.ensembl.org/id/ENSGALG00010023074" } ] } } ], "crossref": [ { "id": "A0A8V0ZR75", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR75", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20595", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20595", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100859215", "url": "https://www.ncbi.nlm.nih.gov/gene/100859215", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "TWSGKGQ", "url": "https://omabrowser.org/oma/group/TWSGKGQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZR75", "url": "https://www.orthodb.org/?gene=A0A8V0ZR75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21797", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21797", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-112382", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2173796", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173796", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6796648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6796648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025001443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025001443", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZR75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEASAGGGAARRWYFTREQLDRSPSRRAGLDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMVQSFTQFHRNSVAPAALFLAAKVEEQPRKLDYVIKVAHACLHPQEPPPDTRSEAYLQQAQDLVILESIILQTLGFEITIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDGTVTLELLDDTAASWAEGLLLLPWFPVQQLLWYNRDGKRHGEMSLNAVSGAGCQHCPSWSGSIPSVAPSIKLTHEFLQILEKTPNRLKRIRNWRASQAARKSKADEHGEDEGLSEQTILNMISRNNSSDMNIAGLMSMSTSSTAAAGPSVPTAADSPGNQSAADAAPAERWLSQHPPSKLDATQSHRTAEGTSGAEHPAQQQQQQQDGAGYPKQGVKNAPSAKVSLKEYRAKHAEELAAQKRQLENMEANVRSQYAYAAKNLLVQQQREREVQQDGNPSPIILKIPIAENPERPPGPEKGDKSSALKLRIPMGGGGGERPLPSKQEEIKMRIKVPSERPDDGGATASIAAKSREHKEKHKGHSSNHHHHNHHSHKHLHPQLGAGPSAALSKRPGDSKHAGQPGAVPHKSCGLFGSSRKRPPPEEGSAHEHQPKVSKGPKGPAPPFPYPHLPGGGHSSDAIASLPTLPSAPSKARGGGHGKSDKGPAGANGHNATQPSDYQDTVNMLHSLLSAQGMQPSQAPPFEFHAYGELLNPRQSARAANTDRPRPPPLPSEPPPPLPPLPK", "length": 791, "header": "tr|A0A8V0ZR75-1|A0A8V0ZR75_CHICK Isoform 1 of Cyclin T1 OS=Gallus gallus OX=9031 GN=CCNT1 PE=3 SV=1 CANONICAL=A0A8V0ZR75-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZR75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75/entry#A0A8V0ZR75-1", "sequence": { "sequence": "MEASAGGGAARRWYFTREQLDRSPSRRAGLDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMVQSFTQFHRNSVAPAALFLAAKVEEQPRKLDYVIKVAHACLHPQEPPPDTRSEAYLQQAQDLVILESIILQTLGFEITIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDGTVTLELLDDTAASWAEGLLLLPWFPVQQLLWYNRDGKRHGEMSLNAVSGAGCQHCPSWSGSIPSVAPSIKLTHEFLQILEKTPNRLKRIRNWRASQAARKSKADEHGEDEGLSEQTILNMISRNNSSDMNIAGLMSMSTSSTAAAGPSVPTAADSPGNQSAADAAPAERWLSQHPPSKLDATQSHRTAEGTSGAEHPAQQQQQQQDGAGYPKQGVKNAPSAKVSLKEYRAKHAEELAAQKRQLENMEANVRSQYAYAAKNLLVQQQREREVQQDGNPSPIILKIPIAENPERPPGPEKGDKSSALKLRIPMGGGGGERPLPSKQEEIKMRIKVPSERPDDGGATASIAAKSREHKEKHKGHSSNHHHHNHHSHKHLHPQLGAGPSAALSKRPGDSKHAGQPGAVPHKSCGLFGSSRKRPPPEEGSAHEHQPKVSKGPKGPAPPFPYPHLPGGGHSSDAIASLPTLPSAPSKARGGGHGKSDKGPAGANGHNATQPSDYQDTVNMLHSLLSAQGMQPSQAPPFEFHAYGELLNPRQSARAANTDRPRPPPLPSEPPPPLPPLPK", "length": 791, "header": "tr|A0A8V0ZR75-1|A0A8V0ZR75_CHICK Isoform 1 of Cyclin T1 OS=Gallus gallus OX=9031 GN=CCNT1 PE=3 SV=1 CANONICAL=A0A8V0ZR75-1" }, "locus": { "chromosome": "34", "start_pos": 91249, "end_pos": 83280, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056193.1", "url": "https://www.ensembl.org/id/ENSGALT00010056193.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034011.1", "url": "https://www.ensembl.org/id/ENSGALP00010034011.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-GGA-2173796", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2173796", "resource": "Reactome", "description": "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" }, { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-6796648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6796648", "resource": "Reactome", "description": "TP53 Regulates Transcription of DNA Repair Genes" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" }, { "id": "R-GGA-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZQB6-1", "protein_name": "Cyclin-T1", "gene_name": "CCNT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGERKNNNKRWYFTREQLENSPSRRFGLDPDEELSCRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFHQNSVAPAALFLAAKVEEQPKKLEHVIKVAHACLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPSRLKGIRNWRACQAARKTKPDDRGPDGNTSEQTILNMISQSSSDTTIAGLMSMSAASTASAVPSLPATEASTSNLSSVKMLPGERWLSSHPPFKVEPAHGHRTSENAALMGVDHSLQQDGSNAFISQRQTSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKKPLEGSENPERPFLEKTDKTALKMRIPMTSGDKTASSKPEEIKMRIKVHAAADKHNSVDDSVAKSREHKEKHKTHPSNHHHHHHNHHSHKHSHPQLPPGPGNKRPGDPKHGSQTSSSAHKPYSLSGSSSSSSSSRKRPLPEEMAGAGYDHAAKTAKSTKSSSINFSFPPLPPVAQLPGHSSDASGLPFSQPSCKSRVPHMKSDKGSSGANGHNATQTIDYQDTVNMLHSLLSAQGVQPTQPAFEFVHSYGEYLNPRAGGMSSRPGNADKPRLPPLPSEPPPPLPPLPK", "length": 727 }, "evidence": [ { "id": "A0A8V0ZR75", "url": "https://omabrowser.org/oma/group/A0A8V0ZR75/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3ILA5-1", "protein_name": "Cyclin-T1", "gene_name": "Ccnt1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGERKNNNKRWYFTREQLENSPSRRFGVDSDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFHRYSMAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPSRLKRIRNWRAYQAAMKTKPDDRGADENTSEQTILNMISQTSSDTTIAGLMSMSTTSTTSAVPSLPASEESSSSLSNVEMLQGERWLSSQPPFKLESSQGHRTSENLALIGVDHSLQHDGSNAFVSQKQTNKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMPIEGSENPERPFLEKADKSALKMRLPVAGGDKAASSKPEEIKMRIKVHSAADKHNSIEDSITKSREHKEKHKPHPSNHHHHHNHHSHKHSHLQLPVGTVNKRPSDPKHSSQSSSTLAHKTYSLSNTLSSSSSSTRKRGPPEETGAAVFDHPAKIAKSTKSSSLNFPFPPLPAMTQLPGHSSDTSGLPFSQPSCKTRVPHMKLDKGPPGANGHNTTQSIDYQDTVNMLHSLLSAQGVQPTQPPAFEFVHSYGEYMNPRAGGISSRSANTDKPRPPPLPSEPPPPLPPLPK", "length": 729 }, "evidence": [ { "id": "A0A8V0ZR75", "url": "https://omabrowser.org/oma/group/A0A8V0ZR75/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O60563-1", "protein_name": "Cyclin-T1", "gene_name": "CCNT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGERKNNNKRWYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPNRLKRIWNWRACEAAKKTKADDRGTDEKTSEQTILNMISQSSSDTTIAGLMSMSTSTTSAVPSLPVSEESSSNLTSVEMLPGKRWLSSQPSFKLEPTQGHRTSENLALTGVDHSLPQDGSNAFISQKQNSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMPIEGSENPERPFLEKADKTALKMRIPVAGGDKAASSKPEEIKMRIKVHAAADKHNSVEDSVTKSREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPVGTGNKRPGDPKHSSQTSNLAHKTYSLSSSFSSSSSTRKRGPSEETGGAVFDHPAKIAKSTKSSSLNFSFPSLPTMGQMPGHSSDTSGLSFSQPSCKTRVPHSKLDKGPTGANGHNTTQTIDYQDTVNMLHSLLSAQGVQPTQPTAFEFVRPYSDYLNPRSGGISSRSGNTDKPRPPPLPSEPPPPLPPLPK", "length": 726 }, "evidence": [ { "id": "A0A8V0ZR75", "url": "https://omabrowser.org/oma/group/A0A8V0ZR75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6T8E9-1", "protein_name": "Cyclin-T1", "gene_name": "CCNT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEGERKNNNKRWYFTREQLENSPSRRFGLDPDKELSNRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFHRNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPNRLKRIWNWRAWQADRKTKADDRGADENSSEQTILNMISQSSSDTTIAGLMSMSASSTTSAVPSLPATEDSKSNLSNVEMLSSERWLSSHPPFKVEPAQGYRKSENLALVGADHSLQQDGSNAFVSQKQNSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMPIEGSENPERPFLEKTDKTALKMRIPMTGGDKAASIKPEEIKMRIKVHTAADKHNSVDDSVTKNREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPAGTGNKRLGDPKHSSQTSTLAHKPYSLSSSFSSSSSSRKRPLPEETGGVAYDHSTKTAKSAKSSSINFSFPPLPTMAQLPGHSSDTSGLHFSQPSCKTRVPHMKLDKSSTGANSHNTPQTTDYQDTVNMLNSLLNAQGVQPTQPPAFEYVHSYGEYMNPRAGGMSSRSGNTDKPRPPPLPSEPPPPLPPLPK", "length": 727 }, "evidence": [ { "id": "A0A8V0ZR75", "url": "https://omabrowser.org/oma/group/A0A8V0ZR75/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9QWV9-1", "protein_name": "Cyclin-T1", "gene_name": "Ccnt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGERKNNNKRWYFTREQLENSPSRRFGVDSDKELSYRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFHRYSMAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPSRLKRIRNWRAYQAAMKTKPDDRGADENTSEQTILNMISQTSSDTTIAGLMSMSTASTSAVPSLPSSEESSSSLTSVDMLQGERWLSSQPPFKLEAAQGHRTSESLALIGVDHSLQQDGSSAFGSQKQASKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHDSHSSVILKMPIESSENPERPFLDKADKSALKMRLPVASGDKAVSSKPEEIKMRIKVHSAGDKHNSIEDSVTKSREHKEKQRTHPSNHHHHHNHHSHRHSHLQLPAGPVSKRPSDPKHSSQTSTLAHKTYSLSSTLSSSSSTRKRGPPEETGAAVFDHPAKIAKSTKSSLNFPFPPLPTMTQLPGHSSDTSGLPFSQPSCKTRVPHMKLDKGPPGANGHNATQSIDYQDTVNMLHSLLSAQGVQPTQAPAFEFVHSYGEYMNPRAGAISSRSGTTDKPRPPPLPSEPPPPLPPLPK", "length": 724 }, "evidence": [ { "id": "A0A8V0ZR75", "url": "https://omabrowser.org/oma/group/A0A8V0ZR75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "RNA polymerase binding", "id": "GO:0070063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070063", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "7SK snRNA binding", "id": "GO:0097322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097322", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "cyclin-dependent protein serine/threonine kinase activator activity", "id": "GO:0061575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "molecular condensate scaffold activity", "id": "GO:0140693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140693", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "cyclin/CDK positive transcription elongation factor complex", "id": "GO:0008024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "P-TEFb complex", "id": "GO:0070691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070691", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { "name": "host-mediated activation of viral transcription", "id": "GO:0043923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043923", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR75", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR75" } ], "pmid": "" }, { 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SV=1 CANONICAL=A0A8V0ZR79-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZR79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR79/entry#A0A8V0ZR79-1", "sequence": { "sequence": 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SV=1 CANONICAL=A0A8V0ZR79-1" }, "locus": { "chromosome": "24", "start_pos": 5261073, "end_pos": 5254334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056198.1", "url": "https://www.ensembl.org/id/ENSGALT00010056198.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034016.1", "url": "https://www.ensembl.org/id/ENSGALP00010034016.1" } ] } }, { "isoform_ac": "A0A8V0ZU80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR79/entry#A0A8V0ZU80-1", "sequence": { "sequence": "MPSAGAAALAWALLWLLAPPPALPEPLDPKKNVEQKDAVFDRTYSDWVASDTLNIYAFNHTVLRNRTEGVRVSVNVLSDHKDLPVLFVVRQKEAVVSFQVPLILRGLFQRKYAYQEVSRTLCQPQTKVEVETQHFFVDVSTLSLNASYQLRVTRVENFVLRTNEAFTFNATASQPQYFKYEFPDGVDSVIVKVTSAMAFPCSVISIQDILCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDEVCGGALPYYPLSKRTSPDEPVDQHNRQKMLEVMVSPAITSEAYVSSMLFCLGIFLSFYVITVLIACWENCRQQKKKGLLAAMDSPSLDTGHPHSIPDSFLGHAPYVGCGYGSFENGSSCSTEAITDSMGSADVSYGYVGERSLENVASRPRLDSLSSVEEDDYDTLADIDYDKNVIRTKQYLCVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNIISNLGYVLLGLLFLLIILQREINYNRALMRNDSHALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAVVIFFSVIGVVFGKGNMVFWIIFSVMHIMATLLLSTQLYYMGRWKLDTGILRRILHVMYTDCVRQCSGPMYVDRMVLLVMGNIINWSLAAYGLLVRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIIGTSVVWGFALFFFFQGLSTWQVGVRPCGVWGGCGAGTVMAAPSCTENTSGVPGAQP", "length": 820, "header": "tr|A0A8V0ZU80-1|A0A8V0ZR79_CHICK Computationally mapped isoform of SID1 transmembrane family member 2 OS=Gallus gallus OX=9031 GN=SIDT2 PE=3 SV=1 CANONICAL=A0A8V0ZR79-1" }, "locus": { "chromosome": "24", "start_pos": 5260854, "end_pos": 5254334, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056205.1", "url": "https://www.ensembl.org/id/ENSGALT00010056205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034022.1", "url": "https://www.ensembl.org/id/ENSGALP00010034022.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR79" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": 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"evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR79" } ], "pmid": "" }, { "name": "AP-1 adaptor complex binding", "id": "GO:0035650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035650", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR79" } ], "pmid": "" }, { "name": "RNA transmembrane transporter activity", "id": "GO:0051033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051033", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR79" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA transport", "id": "GO:0050658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050658", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR79", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR79" } ], "pmid": "" }, { "name": "RNA catabolic process", "id": 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The reference sequence was derived from JAENSK010000227.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001376458", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376458" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR93", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR93" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "PRAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR93", "locus": { "chromosome": "6", "start_pos": 10091468, "end_pos": 10090403, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022512", "url": "https://www.ensembl.org/id/ENSGALG00010022512" } ] } } ], "crossref": [ { "id": "A0A8V0ZR93", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR93", "database": "AlphaFoldDB", 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421570" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_421570.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421570" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR95" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC25A16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR95", "locus": { "chromosome": "6", "start_pos": 11383253, "end_pos": 11399668, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023079", "url": "https://www.ensembl.org/id/ENSGALG00010023079" } ] } } ], "crossref": [ { "id": "A0A8V0ZR95", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZR95", "database": "AlphaFoldDB", "categories": [] }, { "id": "423689", "url": 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"Protein" ] }, { "id": "A0A8V0ZR95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZYQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPAAAGPGAALPPGPARRDFYWLRSFIAGGVAGCCAKTTTAPLDRVKILLQAHNHHYKHLGVFSTLCAVPKKEGYLGLYKGNGAMMIRIFPYGAIQFMAFDQYKKVIKKHLGISGHVHRLMAGSMAGITAVICTYPLDMVRVRLAFQVKGEHKYMGIIHAFKMIYTKEGGFSGFYRGLMPTIVGMAPYAGFSFFTFGTLKSIGLAQAPNLLGRPSLDNPDVLVLKTHINLLCGGIAGAIAQTISYPLDVTRRRMQLGAVLPDSEKCLTMVQTLKYVYQQHGIRRGLYRGLSLNYIRCIPSQAVAFTTYELMKQFLRLN", "length": 320, "header": "tr|A0A8V0ZR95-1|A0A8V0ZR95_CHICK Isoform 1 of Solute carrier family 25 member 16 OS=Gallus gallus OX=9031 GN=SLC25A16 PE=3 SV=1 CANONICAL=A0A8V0ZR95-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZR95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR95/entry#A0A8V0ZR95-1", "sequence": { "sequence": "MASPAAAGPGAALPPGPARRDFYWLRSFIAGGVAGCCAKTTTAPLDRVKILLQAHNHHYKHLGVFSTLCAVPKKEGYLGLYKGNGAMMIRIFPYGAIQFMAFDQYKKVIKKHLGISGHVHRLMAGSMAGITAVICTYPLDMVRVRLAFQVKGEHKYMGIIHAFKMIYTKEGGFSGFYRGLMPTIVGMAPYAGFSFFTFGTLKSIGLAQAPNLLGRPSLDNPDVLVLKTHINLLCGGIAGAIAQTISYPLDVTRRRMQLGAVLPDSEKCLTMVQTLKYVYQQHGIRRGLYRGLSLNYIRCIPSQAVAFTTYELMKQFLRLN", "length": 320, "header": "tr|A0A8V0ZR95-1|A0A8V0ZR95_CHICK Isoform 1 of Solute carrier family 25 member 16 OS=Gallus gallus OX=9031 GN=SLC25A16 PE=3 SV=1 CANONICAL=A0A8V0ZR95-1" }, "locus": { "chromosome": "6", "start_pos": 11399628, "end_pos": 11384650, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056218.1", "url": "https://www.ensembl.org/id/ENSGALT00010056218.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034031.1", "url": "https://www.ensembl.org/id/ENSGALP00010034031.1" } ] } }, { "isoform_ac": "A0A8V0ZYQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR95/entry#A0A8V0ZYQ1-1", "sequence": { "sequence": "MWQGGVAGCCAKTTTAPLDRVKILLQAHNHHYKHLGVFSTLCAVPKKEGYLGLYKGNGAMMIRIFPYGAIQFMAFDQYKKVIKKHLGISGHVHRLMAGSMAGITAVICTYPLDMVRVRLAFQVKGEHKYMGIIHAFKMIYTKEGGFSGFYRGLMPTIVGMAPYAGFSFFTFGTLKSIGLAQAPNLLGRPSLDNPDVLVLKTHINLLCGGIAGAIAQTISYPLDVTRRRMQLGAVLPDSEKCLTMVQTLKYVYQQHGIRRGLYRGLSLNYIRCIPSQAVAFTTYELMKQFLRLN", "length": 293, "header": "tr|A0A8V0ZYQ1-1|A0A8V0ZR95_CHICK Computationally mapped isoform of Solute carrier family 25 member 16 OS=Gallus gallus OX=9031 GN=SLC25A16 PE=3 SV=1 CANONICAL=A0A8V0ZR95-1" }, "locus": { "chromosome": "6", "start_pos": 11399096, "end_pos": 11384650, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056217.1", "url": "https://www.ensembl.org/id/ENSGALT00010056217.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034030.1", "url": "https://www.ensembl.org/id/ENSGALP00010034030.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423689", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423689", "resource": "KEGG Pathway" }, { "id": "R-GGA-199220", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-199220", "resource": "Reactome", "description": "Vitamin B5 (pantothenate) metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LKH1-1", "protein_name": "Mitochondrial coenzyme A transporter SLC25A16", "gene_name": "Slc25a16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAAAALAAADPAPAVPQAAGSGGPASRRDLYWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVLSALRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGHVHRLMAGSMAGMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPTLLGRPSSDNPNVLVLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRETMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN", "length": 329 }, "evidence": [ { "id": "A0A8V0ZR95", "url": "https://omabrowser.org/oma/group/A0A8V0ZR95/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZG52-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "Dna2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPLDDLDLLLLEEDSGAEAVPRMEILQKKADAFFAETVLSRGVDNRYLVLAVETKLNERGAEEKHLLITVSQEGEQEVLCILRNGWSSVPVEPGDIIHIEGDCTSEPWIVDDDFGYFILSPDMLISGTSVASSIRCLRRAVLSETFRVSDTATRQMLIGTILHEVFQKAISESFAPEKLQELALQTLREVRHLKEMYRLNLSQDEVRCEVEEYLPSFSKWADEFMHKGTKAEFPQMHLSLPSDSSDRSSPCNIEVVKSLDIEESIWSPRFGLKGKIDVTVGVKIHRDCKTKYKIMPLELKTGKESNSIEHRGQVILYTLLSQERREDPEAGWLLYLKTGQMYPVPANHLDKRELLKLRNQLAFSLLHRVSRAAAGEEARLLALPQIIEEEKTCKYCSQMGNCALYSRAVEQVHDTSIPEGMRSKIQEGTQHLTRAHLKYFSLWCLMLTLESQSKDTKKSHQSIWLTPASKLEESGNCIGSLVRTEPVKRVCDGHYLHNFQRKNGPMPATNLMAGDRIILSGEERKLFALSKGYVKRIDTAAVTCLLDRNLSTLPETTLFRLDREEKHGDINTPLGNLSKLMENTDSSKRLRELIIDFKEPQFIAYLSSVLPHDAKDTVANILKGLNKPQRQAMKKVLLSKDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLGQSHKVHPDIQKFTEEEMCRLRSIASLAHLEELYNSHPVVATTCMGISHPMFSRKTFDFCIVDEASQISQPICLGPLFFSRRFVLVGDHKQLPPLVLNREARALGMSESLFKRLERNESAVVQLTIQYRMNRKIMSLSNKLTYEGKLECGSDRVANAVITLPNLKDVRLEFYADYSDNPWLAGVFEPDNPVCFLNTDKVPAPEQIENGGVSNVTEARLIVFLTSTFIKAGCSPSDIGIIAPYRQQLRTITDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRSNEDGTLGELLKDWRRLNVAITRAKHKLILLGSVSSLKRFPPLEKLFDHLNAEQLISNLPSREHESLYHILGDCQRD", "length": 1059 }, "evidence": [ { "id": "A0A8V0ZR95", "url": "https://omabrowser.org/oma/group/A0A8V0ZR95/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LSN6-1", "protein_name": "Mitochondrial coenzyme A transporter SLC25A16", "gene_name": "SLC25A16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAAALAAAEPPPAMPQAAGTGGPAARRDFYWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSTLRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGVSGHVHRLMAGSLAGMTAVICTYPLDMVRVRLAFQVKGEHTYTGIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHINLICGGVAGAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRETMKYVYGHHGIRKGLYRGLSLNYIRCVPSQAVAFTTYELMKQFFHLN", "length": 329 }, "evidence": [ { "id": "A0A8V0ZR95", "url": "https://omabrowser.org/oma/group/A0A8V0ZR95/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P16260-1", "protein_name": "Mitochondrial coenzyme A transporter SLC25A16", "gene_name": "SLC25A16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAATAAAALAAADPPPAMPQAAGAGGPTTRRDFYWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN", "length": 332 }, "evidence": [ { "id": "A0A8V0ZR95", "url": "https://omabrowser.org/oma/group/A0A8V0ZR95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q12251-1", "protein_name": "Uncharacterized mitochondrial carrier YPR011C", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAEVLTVLEQPNSIKDFLKQDSNIAFLAGGVAGAVSRTVVSPFERVKILLQVQSSTTSYNRGIFSSIRQVYHEEGTKGLFRGNGLNCIRIFPYSAVQFVVYEACKKKLFHVNGNNGQEQLTNTQRLFSGALCGGCSVVATYPLDLIKTRLSIQTANLSSLNRSKAKSISKPPGIWQLLSETYRLEGGLRGLYRGVWPTSLGVVPYVALNFAVYEQLREFGVNSSDAQPSWKSNLYKLTIGAISGGVAQTITYPFDLLRRRFQVLAMGGNELGFRYTSVWDALVTIGRAEGVSGYYKGLAANLFKVVPSTAVSWLVYEVVCDSVRNW", "length": 326 }, "evidence": [ { "id": "A0A8V0ZR95", "url": "https://omabrowser.org/oma/group/A0A8V0ZR95/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54MZ4-1", "protein_name": "Mitochondrial substrate carrier family protein B", "gene_name": "mcfB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNNNNNNNNNNNNNNNNNNNNNNNNNNDKNNNNNIDSSIKEKKLKEWFDKFDVDKDGSLDSNELKKGFKLHANIDMKDEQITKMMERADSNKNHRIEWDEFLKVASDSSSPEIEDIAEHWLQYSTKPIVHAPADVPSWKLLLSGGVAGAVSRTCTSPLERLKILNQVGHMNLEQNAPKYKGRGIIQSLKTMYTTEGFIGFFKGNGTNVIRIAPYSAIQFLSYEKYKNFLLNNNDQTHLTTYENLFVGGAAGVTSLLCTYPLDLIRSRLTVQVFGNKYNGIADTCKMIIREEGVAGLYKGLFASALGVAPYVAINFTTYENLKKTFIPKDTTPTVVQSLTFGAISGATAQTLTYPIDLIRRRLQVQGIGGKDILYNGTFDAFRKIIRDEGVLGLYNGMIPCYLKVIPAISISFCVYEVMKKILKIDSKKISYQS", "length": 434 }, "evidence": [ { "id": "A0A8V0ZR95", "url": "https://omabrowser.org/oma/group/A0A8V0ZR95/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8C0K5-1", "protein_name": "Mitochondrial coenzyme A transporter SLC25A16", "gene_name": "Slc25a16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALVAAAALAAAEPAPAVPQAAGSGGPTSRRDFYWLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNRHYKHLGVLSTLRAVPQKEGYLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTFITTKLGVSGHVHRLMAGSMAGMTAVICTYPLDVVRVRLAFQVKGEHTYSGIIHAFKTIYAKEGGFLGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSYAPALLGRPSSDNPNVLVLKTHINLLCGGVAGAIAQTISYPFDVTRRRMQLGAVLPEFEKCLTMRETMKYVYGQHGIRRGLYRGLSLNYIRCIPSQAVAFTTYELMKQFFHLN", "length": 332 }, "evidence": [ { "id": "A0A8V0ZR95", "url": "https://omabrowser.org/oma/group/A0A8V0ZR95/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR95" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "coenzyme A transmembrane transporter activity", "id": "GO:0015228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR95" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial coenzyme A transmembrane transport", "id": "GO:1990559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990559", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR95" } ], "pmid": "" }, { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZR95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZR95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRA2-1", "uniprot_ac": "A0A8V0ZRA2", "uniprot_id": "A0A8V0ZRA2_CHICK", "mass": { "chemical_mass": 19619.0, "monoisotopic_mass": 19619.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Coiled-coil domain-containing protein 172", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA2", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZRA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR029618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR22419", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22419", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22419:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22419:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZRA2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VFLPTDAKRKMTEEEDNFTREVTEFNDEYGLTSNRELLIKKKAKTEINDLEKEAAVLKNEMETMEHKNVHLNALQLQKNELKQELFTLKSELKDLEKLIKEAEGTMKALEAEKVQVTEKPQTNPECLRLKKELENYKDDDWESIYETLRTEVEILVQEYKQRKRI", "length": 165, "header": "tr|A0A8V0ZRA2-1|A0A8V0ZRA2_CHICK Isoform 1 of Coiled-coil domain-containing protein 172 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZRA2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRA2/entry#A0A8V0ZRA2-1", "sequence": { "sequence": "VFLPTDAKRKMTEEEDNFTREVTEFNDEYGLTSNRELLIKKKAKTEINDLEKEAAVLKNEMETMEHKNVHLNALQLQKNELKQELFTLKSELKDLEKLIKEAEGTMKALEAEKVQVTEKPQTNPECLRLKKELENYKDDDWESIYETLRTEVEILVQEYKQRKRI", "length": 165, "header": "tr|A0A8V0ZRA2-1|A0A8V0ZRA2_CHICK Isoform 1 of Coiled-coil domain-containing protein 172 OS=Gallus gallus OX=9031 GN= PE=3 SV=1 CANONICAL=A0A8V0ZRA2-1" }, "locus": { "chromosome": "6", "start_pos": 29575234, "end_pos": 29561713, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055149.1", "url": "https://www.ensembl.org/id/ENSGALT00010055149.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033361.1", "url": "https://www.ensembl.org/id/ENSGALP00010033361.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": 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Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. 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"IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424733", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424733", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TEWDRYC", "url": "https://omabrowser.org/oma/group/TEWDRYC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRB8", "url": "https://www.orthodb.org/?gene=A0A8V0ZRB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRC3", "url": "https://www.orthodb.org/?gene=A0A8V0ZRC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWW8", "url": "https://www.orthodb.org/?gene=A0A8V0ZWW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14095", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14095", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14095:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14095:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17958", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17958", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21161", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21161", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004936978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004936978", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWW8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVNFEASLPSGIRAMAATYRLMVTTVNCYSSVVIEQHFQHTVHYCTGTCQVFKQGVACIVAHHSVCAELSVQDANLDHKIPVSENGLALPGNEDYQQMLLNNPRIKKGSLVQASNSLKDITGEAINLASGKIKEFSFEKLKNSSNHVAYRKGRKVRSESFSRRSFDFDMIYGHFSNDENSPPCGFLQSPSPVEKWQESSDAPEVSMNPMVPFSPHSFSEENFITQILEKHKLDGSSGGDIKVCLDILLKCSEDLKKCTDIIKHCIKKKSADSVSGGNSSDPLASSEMIYMNLMRRFSSYLKKLPFEFKPPGYKEASDLGELVNCFHGLQQTLFSPVFGDEQPPRYEDIIQLPSSNAVPVRLPGDQCEVTSTSPSIQTSTVSFTSKSLCSISQENSVRAVKDACVLPQLPATSPSDCTSSTEVLYIEEESDGERVLEKTKRAKEKGDWESLKHSYQLPGSSDVIADVKAEPTRVGSELSHTSEKSNLLKPVSNSVLCGSQAGVSKGEQMCKIDKDEIDKLLLDLEHFSQKMESTFRESPPKESEPACLQVFGWQGRPVLPVALEPKSKPIDPTYPLSKIVETNGHKMEEDDRALLLRILGSIEDFAQELVEFQKGKGSLSKEKEVMQILQETLSTPSQSLLAAQKSYAGAASRDSVPALIQQAPEVIKVQSKQEKKPGRSSPVPLNSVVSPCALPVNKATSSTPLSINIPRFYFPKGLPNVCTNHEEIIARIEEAFTEFEDEKANICEMGKIAKICGCPLYWKAPMFSASGGQRTGCVSVHSFVSLWRKILCSCHDDASRFAYLVAKPSCGYLEQEDFIPLLQDVVETHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITLTELRKSNFLQTLALLEEEDDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQKDLARYSDQALSSRIIERIFSGAVVRGNEVQKEGRMSYADFVWLLISEEDKRNATSIEYWFRCMDLDGDGVLSMYELEYFYEEQCERMEVMGIEPLPFQDLLCQMLDLVKPEREGRVTLRDLKRCRMAHVFYNTFFNLEKYLDSEQRDPFAVQKDFENDGPEPSDWDRYAAEEYEILVAEESGNEQLQEGNRKGMKALKRYPLL", "length": 1123, "header": "tr|A0A8V0ZRB8-1|A0A8V0ZRB8_CHICK Isoform 1 of Protein phosphatase 2 regulatory subunit B''alpha OS=Gallus gallus OX=9031 GN=PPP2R3A PE=4 SV=1 CANONICAL=A0A8V0ZRB8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8/entry#A0A8V0ZRB8-1", "sequence": { "sequence": "MVNFEASLPSGIRAMAATYRLMVTTVNCYSSVVIEQHFQHTVHYCTGTCQVFKQGVACIVAHHSVCAELSVQDANLDHKIPVSENGLALPGNEDYQQMLLNNPRIKKGSLVQASNSLKDITGEAINLASGKIKEFSFEKLKNSSNHVAYRKGRKVRSESFSRRSFDFDMIYGHFSNDENSPPCGFLQSPSPVEKWQESSDAPEVSMNPMVPFSPHSFSEENFITQILEKHKLDGSSGGDIKVCLDILLKCSEDLKKCTDIIKHCIKKKSADSVSGGNSSDPLASSEMIYMNLMRRFSSYLKKLPFEFKPPGYKEASDLGELVNCFHGLQQTLFSPVFGDEQPPRYEDIIQLPSSNAVPVRLPGDQCEVTSTSPSIQTSTVSFTSKSLCSISQENSVRAVKDACVLPQLPATSPSDCTSSTEVLYIEEESDGERVLEKTKRAKEKGDWESLKHSYQLPGSSDVIADVKAEPTRVGSELSHTSEKSNLLKPVSNSVLCGSQAGVSKGEQMCKIDKDEIDKLLLDLEHFSQKMESTFRESPPKESEPACLQVFGWQGRPVLPVALEPKSKPIDPTYPLSKIVETNGHKMEEDDRALLLRILGSIEDFAQELVEFQKGKGSLSKEKEVMQILQETLSTPSQSLLAAQKSYAGAASRDSVPALIQQAPEVIKVQSKQEKKPGRSSPVPLNSVVSPCALPVNKATSSTPLSINIPRFYFPKGLPNVCTNHEEIIARIEEAFTEFEDEKANICEMGKIAKICGCPLYWKAPMFSASGGQRTGCVSVHSFVSLWRKILCSCHDDASRFAYLVAKPSCGYLEQEDFIPLLQDVVETHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITLTELRKSNFLQTLALLEEEDDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQKDLARYSDQALSSRIIERIFSGAVVRGNEVQKEGRMSYADFVWLLISEEDKRNATSIEYWFRCMDLDGDGVLSMYELEYFYEEQCERMEVMGIEPLPFQDLLCQMLDLVKPEREGRVTLRDLKRCRMAHVFYNTFFNLEKYLDSEQRDPFAVQKDFENDGPEPSDWDRYAAEEYEILVAEESGNEQLQEGNRKGMKALKRYPLL", "length": 1123, "header": "tr|A0A8V0ZRB8-1|A0A8V0ZRB8_CHICK Isoform 1 of Protein phosphatase 2 regulatory subunit B''alpha OS=Gallus gallus OX=9031 GN=PPP2R3A PE=4 SV=1 CANONICAL=A0A8V0ZRB8-1" }, "locus": { "chromosome": "9", "start_pos": 256944, "end_pos": 217760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055172.1", "url": "https://www.ensembl.org/id/ENSGALT00010055172.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033377.1", "url": "https://www.ensembl.org/id/ENSGALP00010033377.1" } ] } }, { "isoform_ac": "A0A8V0ZRC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8/entry#A0A8V0ZRC3-1", "sequence": { "sequence": "MVNFEASLPSGIRAMAATYRLMVTTVNCYSSVVIEQHFQHTVHYCTGTCQVFKQGVACIVAHHSVCAELSVQDANLDHKIPVSENGLALPGNEDYQQMLLNNPRIKKGSLVQASNSLKDITGEAINLASGKIKEFSFEKLKNSSNHVAYRKGRKVRSESFSRRSFDFDMIYGHFSNDENSPPCGFLQSPSPVEKWQESSDAPEVSMNPMVPFSPHSFSEENFITQILEKHKLDGSSGGDIKVCLDILLKCSEDLKKCTDIIKHCIKKKSADSVSGGNSSDPLASSEMIYMNLMRRFSSYLKKLPFEFKPPGYKEASDLGELVNCFHGLQQTLFSPVFGDEQPPRYEDIIQLPSSNAVPVRLPGDQCEVTSTSPSIQTSTVSFTSKSLCSISQENSVRAVKDACVLPQLPATSPSDCTSSTEVLYIEEESDGERVLEKTKRAKEKGDWESLKHSYQLPGSSDVIADVKAEPTRVGSELSHTSEKSNLLKPVSNSVLCGSQAGVSKGEQMCKIDKDEIDKLLLDLEHFSQKMESTFRESPPKESEPACLQVFGWQGRPVLPVALEPKSKPIDPTYPLSKIVETNGHKMEEDDRALLLRILGSIEDFAQELVEFQKGKGSLSKEKEVMQILQETLSTPSQSLLAAQKSYAGAASRDSVPALIQQAPEVIKVQSKQEKKPGRSSPVPLNSVVSPCALPVNKATSSTPLSINIPRFYFPKGLPNVCTNHEEIIARIEEAFTEFEDEKANICEMGKIAKICGCPLYWKAPMFSASGGQRTGCVSVHSFVSLWRKILCSCHDDASRFAYLVAKPSCGYLEQEDFIPLLQDVVETHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITLTELRKSNFLQTLALLEEEDDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQKDLARYSDQALSSRIIERIFSGAVVRGNEVQKEGRMSYADFVWLLISEEDKRNATSIEYWFRCMDLDGDGVLSMYELEYFYEEQCERMEVMGIEPLPFQDLLCQMLDLVKPEREGRVTLRDLKRCRMAHVFYNTFFNLEKYLDSEQRDPFAVQKDFENDGPEPSDWDRYAAEEYEILVAEESGNEQLQEGSL", "length": 1111, "header": "tr|A0A8V0ZRC3-1|A0A8V0ZRC3_CHICK Computationally mapped isoform of Protein phosphatase 2 regulatory subunit B''alpha OS=Gallus gallus OX=9031 GN=PPP2R3A PE=4 SV=1 CANONICAL=A0A8V0ZRB8-1" }, "locus": { "chromosome": "9", "start_pos": 258902, "end_pos": 217760, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055179.1", "url": "https://www.ensembl.org/id/ENSGALT00010055179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033382.1", "url": "https://www.ensembl.org/id/ENSGALP00010033382.1" } ] } }, { "isoform_ac": "A0A8V0ZWW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8/entry#A0A8V0ZWW8-1", "sequence": { "sequence": "MLLHEAICHFLPVKIKAKKITYWFCRGLLPSPRASSEECNICLELTRMMIKESSLRRDPDLGGELALLAKGCDFVLPSRFKKRLKSFQQAQVQSKQEKKPGRSSPVPLNSVVSPCALPVNKATSSTPLSINIPRFYFPKGLPNVCTNHEEIIARIEEAFTEFEDEKANICEMGKIAKICGCPLYWKAPMFSASGGQRTGCVSVHSFVSLWRKILCSCHDDASRFAYLVAKPSCGYLEQEDFIPLLQDVVETHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITLTELRKSNFLQTLALLEEEDDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQKDLARYSDQALSSRIIERIFSGAVVRGNEVQKEGRMSYADFVWLLISEEDKRNATSIEYWFRCMDLDGDGVLSMYELEYFYEEQCERMEVMGIEPLPFQDLLCQMLDLVKPEREGRVTLRDLKRCRMAHVFYNTFFNLEKYLDSEQRDPFAVQKDFENDGPEPSDWDRYAAEEYEILVAEESGNEQLQEGSFEEDYETDEVLSPSETGDKSN", "length": 555, "header": "tr|A0A8V0ZWW8-1|A0A8V0ZRB8_CHICK Computationally mapped isoform of Protein phosphatase 2 regulatory subunit B''alpha OS=Gallus gallus OX=9031 GN=PPP2R3A PE=4 SV=1 CANONICAL=A0A8V0ZRB8-1" }, "locus": { "chromosome": "9", "start_pos": 257598, "end_pos": 226085, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055167.1", "url": "https://www.ensembl.org/id/ENSGALT00010055167.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033374.1", "url": "https://www.ensembl.org/id/ENSGALP00010033374.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424733", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424733", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AAK4-1", "protein_name": "Protein phosphatase 2 regulatory subunit B''alpha", "gene_name": "PPP2R3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFAHGVDCIVVHHSVCADLLHIPVSQFKDADLDSMFLPHENGFSSAEGDYPHQALTGIPRVKKGSAFQNTCNLKDIAGEAISFASGKIKEFSLEKLKNSNHAAYKKGRKVKSDSFNRRSVDLDLLCGHYNNDGNSPSFGLLRSSSVEEKSLSHRNSLDMNLTSMLLHNFSEEDLVTQILEKHKIDNFSSGTDIKICLDILLKCSEDLKKCTDIIKQCIKKKSGSSIKEGNGNDAISSSESVYMNVMTRLASYLKKLPFEFMQSGTNEAIDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSAPDSGQFQTIELQDDKHSSRKTDTVKSIPNNSTNSLYNLGISDPRTLKDVQLQSQPSPMSPLENVSSGDLMETLYIEEETDGKKALDKGQRTENGPSQDLLKVNEDRAEFSDCGTHLKKCPASMQNEIGKIFEKPVVSLPGEGLKSEVSKVEEGNHRDFMNPNSQEEIDKLLMDLESFSQKMETSLREPFAKDKSSNSLNSHSPLTGQLPLDLDPKSKVSSPTEKAPPSCLTRIIETNGHKIEEEDRALLLRILESIEDFAQELVECKSGRGSLSQEKEMMQILQETLTTSPQSNLSVCRSPVGDKAKDATSVVLIQQTPEVIKIQNKPEKKPGTPLPPPATFPSSPRPLSPVPHVNNVVNAALSINIPRFYFPEGLPDACSNHEQTLSRIESAFMEIEDQKADIFEMGKIAKVCGCPLYWKAPMFRAAGGERTGFVSAQSFIAMWRKLLSNHHDDASKFICLLARPGCSSLEQDDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDSDHDLYISQADLSRYNDQASSNRIIERIFSGAVTRGKSVQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPASDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGSFEDYETEDPASPSETGNKGNKIVTSSLSEKCGKLQSVDEE", "length": 1151 }, "evidence": [ { "id": "A0A8V0ZRB8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRB8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "somatic muscle development", "id": "GO:0007525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8" } ], "pmid": "" }, { "name": "regulation of cell migration involved in somitogenic axis elongation", "id": "GO:0090249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8" } ], "pmid": "" }, { "name": "somitogenesis", "id": "GO:0001756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8" } ], "pmid": "" }, { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRB8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" }, { "start_pos": 972, "end_pos": 974, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRB8" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 971, "end_pos": 1006, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 277, "end_pos": 279 }, { "start_pos": 857, "end_pos": 859 }, { "start_pos": 972, "end_pos": 974 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRD0-1", "uniprot_ac": "A0A8V0ZRD0", "uniprot_id": "A0A8V0ZRD0_CHICK", "mass": { "chemical_mass": 53094.0, "monoisotopic_mass": 53094.0 }, "refseq": { "ac": "XP_004943715", "name": "ADP-dependent glucokinase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943715" }, "gene_names": [ { "name": "ADPGK", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0" } ] }, { "name": "ADPGK", "type": "synonym", "evidence": [ { "id": "XP_004943715", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943715" } ] } ], "protein_names": [ { "name": "ADP dependent glucokinase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0/entry#names_and_taxonomy" } ] }, { "name": "ADP-dependent glucokinase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943715", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943715" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943715" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADPGK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0", "locus": { "chromosome": "10", "start_pos": 1749310, "end_pos": 1762610, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021594", "url": "https://www.ensembl.org/id/ENSGALG00010021594" } ] } } ], "crossref": [ { "id": "A0A8V0ZRD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01938", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01938", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415317", "url": "https://www.ncbi.nlm.nih.gov/gene/415317", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FIHYMGR", "url": "https://omabrowser.org/oma/group/FIHYMGR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRD0", "url": "https://www.orthodb.org/?gene=A0A8V0ZRD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21208:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21208:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04587", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04587", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-70171", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70171", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_004943715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943715", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWQRSVCVGLLALALGYLCLLGPQLPPSVLQHLSASLLGGLSRAGSLESRMVAAWQAAIVRPARGWGRVAVGVNACVDVVLSGVKLLEALGLKPGSGKNHDVLNSRQDLREAFTHFMEKGAAAERFFSDAESFHHIAQTASEHPGAQLYVGGNAALIGQKLAANPDLKILLCGPVGPKLHELLDDSVVVPPESMQERDEFHLILEYQAGEEWGQVKAPNANRFIFSHDLSNGALNMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKEMRHRRLMEAVASISDIPTDIPIHLELASMTDQDFMSNIVHQQVFPLVNSIGLNEQELLFLTQSASGPHASLASWNGVPDVGAVSDILFWILKEHGKIADRASDLTRIHFHTLAYHILATVDGHWGNQVAAVAAGARAAGVQACATETIDTSKVFLKAPLEFVTSQIDAPSKISLNPDEPVVHWHREGISFHFTPVLVCKDPVRTVGLGDAISAEGLLYSEIYLQ", "length": 490, "header": "tr|A0A8V0ZRD0-1|A0A8V0ZRD0_CHICK Isoform 1 of ADP dependent glucokinase OS=Gallus gallus OX=9031 GN=ADPGK PE=1 SV=1 CANONICAL=A0A8V0ZRD0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0/entry#A0A8V0ZRD0-1", "sequence": { "sequence": "MWQRSVCVGLLALALGYLCLLGPQLPPSVLQHLSASLLGGLSRAGSLESRMVAAWQAAIVRPARGWGRVAVGVNACVDVVLSGVKLLEALGLKPGSGKNHDVLNSRQDLREAFTHFMEKGAAAERFFSDAESFHHIAQTASEHPGAQLYVGGNAALIGQKLAANPDLKILLCGPVGPKLHELLDDSVVVPPESMQERDEFHLILEYQAGEEWGQVKAPNANRFIFSHDLSNGALNMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKEMRHRRLMEAVASISDIPTDIPIHLELASMTDQDFMSNIVHQQVFPLVNSIGLNEQELLFLTQSASGPHASLASWNGVPDVGAVSDILFWILKEHGKIADRASDLTRIHFHTLAYHILATVDGHWGNQVAAVAAGARAAGVQACATETIDTSKVFLKAPLEFVTSQIDAPSKISLNPDEPVVHWHREGISFHFTPVLVCKDPVRTVGLGDAISAEGLLYSEIYLQ", "length": 490, "header": "tr|A0A8V0ZRD0-1|A0A8V0ZRD0_CHICK Isoform 1 of ADP dependent glucokinase OS=Gallus gallus OX=9031 GN=ADPGK PE=1 SV=1 CANONICAL=A0A8V0ZRD0-1" }, "locus": { "chromosome": "10", "start_pos": 1762588, "end_pos": 1752701, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052417.1", "url": "https://www.ensembl.org/id/ENSGALT00010052417.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031326.1", "url": "https://www.ensembl.org/id/ENSGALP00010031326.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-70171", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-70171", "resource": "Reactome", "description": "Glycolysis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QK01-1", "protein_name": "ADP-dependent glucokinase", "gene_name": "ADPGK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALWRGSVYAGFFALAVGCVFLLEPQLPGSALRSLWNSLQLGPVPSPLGPGSPEGRLAAAWDALIVRPARSWRRVAVGVNACVDVVLSGVKLLQALGLNPGTGKDHTELHSRNDLEEAFIHFMGKGAAAERFFSDKESFHDIAQIASEFPGAQHYVGGNAALIGQKFAANSDLKVLLCGPVGPKLHELLDDNVFVPPESLQEMDEFHLILEYQAGEEWGQLKAPHANRFIFSHDLSNGAMNMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKEFQRKRLLEVVASISDIPTGIPVHLELASMTNRELMGSIVHQQVFPAVTSLGLNEQELLFLSQSASGPHSSLSAWTGVPDVGMVSDILFWILKEHGRSESRASDLTRIHFHTLAYHILATVDGHWANQLAAVAAGARVAGTQACATATIDTHRVSLRAPLEFVTSRSEAGSRIVLNPNEPVVEWHREGVSFHFSPVLVCKDPVRTVGLGDAISAEGLFYSEVHPHH", "length": 497 }, "evidence": [ { "id": "A0A8V0ZRD0", "url": "https://omabrowser.org/oma/group/A0A8V0ZRD0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2VE47-1", "protein_name": "ADP-dependent glucokinase", "gene_name": "ADPGK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALWRGSAYAGFLALAVGCVFLLEPQLPGSALRSLWSSLQLGPAPAPPGVGSPEGRLAAAWDALIVRPARRWRRVAVGVNACVDVVLSGVKLLQALGLSPGNGKDHSELHSRNDLEEAFVHFMGKGAAAERFFSDKETFHDIAQVASEFPEAQHYVGGNAALIGQKFAANSDLKVLLCGPVGPKLHELLDDNVFVPPESLQEVDEFHLILEYQAGEEWDQLKAPHANRFIFSHDLSNGAMNMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKEFQRKRLLEVVTSISDIPTGVPVHLELASMTNKELMSTIVHQQVFPAVTSLGLNEQELLFLSQSASGPHSSLSSWNGVPDVGVVSDILFWILKEHGKSESRASDLSRIHFHTLAYHILATVDGHWANQLAAVAAGARVAATQACATETIDTRRVSLKAPHEFMTSRLEAGSRVVLNPNEPVVEWHREGVSFHFTPVLVCKDPVRTVGLGDAISAEGLFYSEVHPHL", "length": 497 }, "evidence": [ { "id": "A0A8V0ZRD0", "url": "https://omabrowser.org/oma/group/A0A8V0ZRD0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3V784-1", "protein_name": "ADP-dependent glucokinase", "gene_name": "Adpgk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALWRGSACAGFLALAVGCVFLLEPELPGTALRSLWSSLRLGPAPVPPGSLSPESRLAAAWDALIVQPARRWRRVAVGVNACVDVVISGVKLLQALGLSPGSGRDHAVLHSRSDLEEAFVHFMGKGAAAERFFSDRETFHDIAQAASEFPGAQHYVGGNAALIGQKFAANPDLKVLLCGPIGPKLHELLDDNVFVPPESLQEEDEFHLILEYLAGEEWGPFKAPQANRFIFSHDLSNGAMNMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRKRLLEVVTSISDIPTGIPVHLELASMTNRELMSSIVHQQVFPAVASLGLNEQELLFLSQSASGPHASLSSWDGVPDVGMVSDILFWILKEHGRSKSRSSDLTRIHFHTLVYHILATVDGHWANQLAAVAAGARVAGTQACATETIDTNRVSLRAPQEFMTSRLEPGSRIVLNPNKPVVEWHREGVTFHFTPVLVCKDPVRTVGLGDAISAEGLFYSEAYPD", "length": 496 }, "evidence": [ { "id": "A0A8V0ZRD0", "url": "https://omabrowser.org/oma/group/A0A8V0ZRD0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54K22-1", "protein_name": "Uncharacterized protein", "gene_name": "glk", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKRQTKNSPPLVGNSSPTSQSSQSPEISKKKLKKIEQKANRPKILVERPLSNLKFGGLVVFFICLVIFYIYLRINPLYDSGNNSNNLNNNNDNNNTNINIIDDIKSMKKIENGLKDIAKYKEWNEECKNKTIAVGYNTNLDLVVDAIELMDKLKLKSSIHNRPMSKEVIKSLDDFEQTFSHYFKSGSAAERMIENEDTFSAILAAALQSESKQFYTGGNAGIMANRLVADGCRVYLGGIIGKKLKELLSPSVSIIGYQSENGEEFDEIHLIMEYNKQSRWGSISPPRSNRFIISRDNTNSHLMTMESFHQEIEKKQPDLLLLSGLHLLTEEAQERRVNDMVNLLKQIPYNNNPSNFLNHPSLNVPIHLELASIASPSYINLLAKKIIPFVDSVGLNEQELGFIYVSTGGKKFSLDDFKEPSVNVVVNALLHIMEISFHYATTTTTSTTADRNVDDNILGDFGIPTMSKQRLLTRIHFHYLSFHLIITKSYSQWSPKLTSASVAASSIEATFQACRFNSVELLLPLSVEVDYRYTPGATKSIIIDPSSPVTTWQDSGYEFHLAPVLVCKSPLKTVGLGDSISTMGFLYQTIKSNEN", "length": 596 }, "evidence": [ { "id": "A0A8V0ZRD0", "url": "https://omabrowser.org/oma/group/A0A8V0ZRD0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8VDL4-1", "protein_name": "ADP-dependent glucokinase", "gene_name": "Adpgk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALWRGSACAGFLALAVGCVFLLEPELPGTALRSLWSSLRLGPAPVPVGPLSPESRLAAAWDALIAQPARRWRRVAVGVNACVDVVISGVKLLQALGLSPGSGKDHAILHSRSDLEEAFLYFMGKGAAAERFFSDKETFHDIAQAASEFPGAQHYVGGNAALIGQRFAANTDLKVLLCGPIGPKLHELLDDNVFVPPESLQEEDEFHLILEYLAGEEWGPFKAPHANRFIFSHDLSNGAMNMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRKRLLEVVTAISDIPTGIPVHLELASMTNRELMSSIVHQQVFPAVASLGLNEQELLFLSQSASGPHSSLSSWDGVPDVGMVSDILFWILKEHGRSENRASDLTRIHFHTLVYHILATVDGHWANQLAAVAAGARVAGTQACATETIDTNRVSLRAPQEFTTSHLESGSRIVLNPDKPVVEWHREGITFHFTPVLVCKDPVRTVGLGDAISAEGLFYSEARPD", "length": 496 }, "evidence": [ { "id": "A0A8V0ZRD0", "url": "https://omabrowser.org/oma/group/A0A8V0ZRD0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BRR6-1", "protein_name": "ADP-dependent glucokinase", "gene_name": "ADPGK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALWRGSAYAGFLALAVGCVFLLEPELPGSALRSLWSSLCLGPAPAPPGPVSPEGRLAAAWDALIVRPVRRWRRVAVGVNACVDVVLSGVKLLQALGLSPGNGKDHSILHSRNDLEEAFIHFMGKGAAAERFFSDKETFHDIAQVASEFPGAQHYVGGNAALIGQKFAANSDLKVLLCGPVGPKLHELLDDNVFVPPESLQEVDEFHLILEYQAGEEWGQLKAPHANRFIFSHDLSNGAMNMLEVFVSSLEEFQPDLVVLSGLHMMEGQSKELQRKRLLEVVTSISDIPTGIPVHLELASMTNRELMSSIVHQQVFPAVTSLGLNEQELLFLTQSASGPHSSLSSWNGVPDVGMVSDILFWILKEHGRSKSRASDLTRIHFHTLVYHILATVDGHWANQLAAVAAGARVAGTQACATETIDTSRVSLRAPQEFMTSHSEAGSRIVLNPNKPVVEWHREGISFHFTPVLVCKDPIRTVGLGDAISAEGLFYSEVHPHY", "length": 497 }, "evidence": [ { "id": "A0A8V0ZRD0", "url": "https://omabrowser.org/oma/group/A0A8V0ZRD0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0" } ], "pmid": "" }, { "name": "ADP-specific glucokinase activity", "id": "GO:0043843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043843", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "glucose metabolic process", "id": "GO:0006006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006006", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0" } ], "pmid": "" }, { "name": "glycolytic process", "id": "GO:0006096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004950095.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004950095", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950095" } ] }, { "annotation": "May function as a co-chaperone.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD2#function" }, { "database": "UniProtKB", "id": "ARBA00002080", "url": "https://www.uniprot.org/uniprotkb/ARBA00002080#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DNAJC22", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD2", "locus": { "chromosome": "34", "start_pos": 1860873, "end_pos": 1863236, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023099", "url": "https://www.ensembl.org/id/ENSGALG00010023099" } ] } } ], "crossref": [ { "id": "A0A8V0ZRD2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "430880", "url": "https://www.ncbi.nlm.nih.gov/gene/430880", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:430880", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430880", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IFYGHPI", "url": "https://omabrowser.org/oma/group/IFYGHPI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRD2", "url": "https://www.orthodb.org/?gene=A0A8V0ZRD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44733", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44733", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44733:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44733:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05154", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05154", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004950095", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004950095", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKRLLVAYGLWALGGPLGLHHLYLGRDSHALLWMLTLGGFGAGWLSDLWHLHRWVAMANSTGSRQGGAVPALSPIRLAGQVVVGTYFGLMAALALPWVPQLLAQPLAVGLGVLLTASVGEQSTKAHRVLTAAFLTSLLFQAQLLAVLPSSLAAGMAAQRHRRYQHPVGPPLRLRARLFRLGMAYLAFAIPVGYSLLHGTAGALGWLGAVPMRSLQSLAWLLGLRGGPGGCTEKQLWAYRVLGIPPGSGTEEVQRSYRELVKVWHPDHNRLRAEEAEQRFIELQEAYEVLGGPRRAAAGGG", "length": 301, "header": "tr|A0A8V0ZRD2-1|A0A8V0ZRD2_CHICK Isoform 1 of DnaJ homolog subfamily C member 22 OS=Gallus gallus OX=9031 GN=DNAJC22 PE=4 SV=1 CANONICAL=A0A8V0ZRD2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD2/entry#A0A8V0ZRD2-1", "sequence": { "sequence": "MAKRLLVAYGLWALGGPLGLHHLYLGRDSHALLWMLTLGGFGAGWLSDLWHLHRWVAMANSTGSRQGGAVPALSPIRLAGQVVVGTYFGLMAALALPWVPQLLAQPLAVGLGVLLTASVGEQSTKAHRVLTAAFLTSLLFQAQLLAVLPSSLAAGMAAQRHRRYQHPVGPPLRLRARLFRLGMAYLAFAIPVGYSLLHGTAGALGWLGAVPMRSLQSLAWLLGLRGGPGGCTEKQLWAYRVLGIPPGSGTEEVQRSYRELVKVWHPDHNRLRAEEAEQRFIELQEAYEVLGGPRRAAAGGG", "length": 301, "header": "tr|A0A8V0ZRD2-1|A0A8V0ZRD2_CHICK Isoform 1 of DnaJ homolog subfamily C member 22 OS=Gallus gallus OX=9031 GN=DNAJC22 PE=4 SV=1 CANONICAL=A0A8V0ZRD2-1" }, "locus": { "chromosome": "34", "start_pos": 1862309, "end_pos": 1861067, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056281.1", "url": "https://www.ensembl.org/id/ENSGALT00010056281.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034067.1", "url": "https://www.ensembl.org/id/ENSGALP00010034067.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:430880", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:430880", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD2" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 237, "end_pos": 295, "start_aa": "Trp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRD3-1", "uniprot_ac": "A0A8V0ZRD3", "uniprot_id": "A0A8V0ZRD3_CHICK", "mass": { "chemical_mass": 19695.0, "monoisotopic_mass": 19695.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD3", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZRD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0ZRD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADTAAMGQSGCGSWLQGWGWSTMIEKKKILNACVTFGCRVPSCYSELLEVGSGGRCGAAGGYGCTCGAAGGSGGMCEAAGDSGGRCGAAGGSGGRCGAAGSYGGRCGAAGSFGGRCGAAGGSGDRCGAAGGSGGRCGAAGSYGGRCGAAGSFGGRCGAAGGSGDRCGAAGGSGGRCGVAGGSRGTCGAPICCSRSFQEISGIERKKKKRTN", "length": 212, "header": "tr|A0A8V0ZRD3-1|A0A8V0ZRD3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZRD3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD3/entry#A0A8V0ZRD3-1", "sequence": { "sequence": "MADTAAMGQSGCGSWLQGWGWSTMIEKKKILNACVTFGCRVPSCYSELLEVGSGGRCGAAGGYGCTCGAAGGSGGMCEAAGDSGGRCGAAGGSGGRCGAAGSYGGRCGAAGSFGGRCGAAGGSGDRCGAAGGSGGRCGAAGSYGGRCGAAGSFGGRCGAAGGSGDRCGAAGGSGGRCGVAGGSRGTCGAPICCSRSFQEISGIERKKKKRTN", "length": 212, "header": "tr|A0A8V0ZRD3-1|A0A8V0ZRD3_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZRD3-1" }, "locus": { "chromosome": "34", "start_pos": 2096533, "end_pos": 2094878, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059056.1", "url": "https://www.ensembl.org/id/ENSGALT00010059056.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036020.1", "url": "https://www.ensembl.org/id/ENSGALP00010036020.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRF1-1", "uniprot_ac": "A0A8V0ZRF1", "uniprot_id": "A0A8V0ZRF1_CHICK", "mass": { "chemical_mass": 38082.0, "monoisotopic_mass": 38082.0 }, "refseq": { "ac": "NP_001264461", "name": "G-protein coupled receptor 146", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264461" }, "gene_names": [ { "name": "GPR146", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1" } ] }, { "name": "GPR146", "type": "synonym", "evidence": [ { "id": "NP_001264461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264461" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 146", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 146", "type": "synonym", "evidence": [ { "id": "NP_001264461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264461" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267660.9150.1, SRR13267661.9111.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Sep 23, 2021 this sequence version replaced NP_001264461.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the functional protein. Variants 1, 2 and 3 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001264461", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264461" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GPR146", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1", "locus": { "chromosome": "14", "start_pos": 2344136, "end_pos": 2305886, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022540", "url": "https://www.ensembl.org/id/ENSGALG00010022540" } ] } } ], "crossref": [ { "id": "cd14990", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14990", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416456", "url": "https://www.ncbi.nlm.nih.gov/gene/416456", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416456", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416456", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YICSHVA", "url": "https://omabrowser.org/oma/group/YICSHVA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRD6", "url": "https://www.orthodb.org/?gene=A0A8V0ZRD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRF1", "url": "https://www.orthodb.org/?gene=A0A8V0ZRF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWE1", "url": "https://www.orthodb.org/?gene=A0A8V0ZWE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24226:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24226:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264461", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264461", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWSCETLNSTDNREDQHLCQDFHFVLSIFSLLYLIICFPIGLCYNGLLVLVNLYNKATMTMPDVYFVNMAIAGLIINALAPMYLLGLANTKWAIWNSNNEVYITLLILFNVSSLVTMYSTTLLSLDYYIERALPRTYMSSVYNTKHVCGFIWGGAMLTSFSSLLFYVCNHVSTKIIECSKMQNKEAADAIMVFIGYVVPAVAVLYALILILRIRKEATPLDQDTGRLDPSVHRLLIATVCTQFTLWTPYYVTLLVSTFTYARGRPADENYSRILHFTKILSKFLAFSSSFVMPLLYRYINKNFPNKLRRLLKKIHCGNQGCSHERTVVQQVMT", "length": 333, "header": "tr|A0A8V0ZRF1-1|A0A8V0ZRF1_CHICK Isoform 1 of G protein-coupled receptor 146 OS=Gallus gallus OX=9031 GN=GPR146 PE=4 SV=1 CANONICAL=A0A8V0ZRF1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1/entry#A0A8V0ZRD6-1", "sequence": { "sequence": "MESGEDWPRPGWGLSAFAGRKASTEKLVTSREDTRAEITMWSCETLNSTDNREDQHLCQDFHFVLSIFSLLYLIICFPIGLCYNGLLVLVNLYNKATMTMPDVYFVNMAIAGLIINALAPMYLLGLANTKWAIWNSNNEVYITLLILFNVSSLVTMYSTTLLSLDYYIERALPRTYMSSVYNTKHVCGFIWGGAMLTSFSSLLFYVCNHVSTKIIECSKMQNKEAADAIMVFIGYVVPAVAVLYALILILRIRKEATPLDQDTGRLDPSVHRLLIATVCTQFTLWTPYYVTLLVSTFTYARGRPADENYSRILHFTKILSKFLAFSSSFVMPLLYRYINKNFPNKLRRLLKKIHCGNQGCSHERTVVQQVMT", "length": 372, "header": "tr|A0A8V0ZRD6-1|A0A8V0ZRF1_CHICK Computationally mapped isoform of G protein-coupled receptor 146 OS=Gallus gallus OX=9031 GN=GPR146 PE=4 SV=1 CANONICAL=A0A8V0ZRF1-1" }, "locus": { "chromosome": "14", "start_pos": 2339156, "end_pos": 2335868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054849.1", "url": "https://www.ensembl.org/id/ENSGALT00010054849.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033151.1", "url": "https://www.ensembl.org/id/ENSGALP00010033151.1" } ] } }, { "isoform_ac": "A0A8V0ZRF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1/entry#A0A8V0ZRF1-1", "sequence": { "sequence": "MWSCETLNSTDNREDQHLCQDFHFVLSIFSLLYLIICFPIGLCYNGLLVLVNLYNKATMTMPDVYFVNMAIAGLIINALAPMYLLGLANTKWAIWNSNNEVYITLLILFNVSSLVTMYSTTLLSLDYYIERALPRTYMSSVYNTKHVCGFIWGGAMLTSFSSLLFYVCNHVSTKIIECSKMQNKEAADAIMVFIGYVVPAVAVLYALILILRIRKEATPLDQDTGRLDPSVHRLLIATVCTQFTLWTPYYVTLLVSTFTYARGRPADENYSRILHFTKILSKFLAFSSSFVMPLLYRYINKNFPNKLRRLLKKIHCGNQGCSHERTVVQQVMT", "length": 333, "header": "tr|A0A8V0ZRF1-1|A0A8V0ZRF1_CHICK Isoform 1 of G protein-coupled receptor 146 OS=Gallus gallus OX=9031 GN=GPR146 PE=4 SV=1 CANONICAL=A0A8V0ZRF1-1" }, "locus": { "chromosome": "14", "start_pos": 2339156, "end_pos": 2338158, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054868.1", "url": "https://www.ensembl.org/id/ENSGALT00010054868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033166.1", "url": "https://www.ensembl.org/id/ENSGALP00010033166.1" } ] } }, { "isoform_ac": "A0A8V0ZWE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1/entry#A0A8V0ZWE1-1", "sequence": { "sequence": "MWSCETLNSTDNREDQHLCQDFHFVLSIFSLLYLIICFPIGLCYNGLLVLVNLYNKATMTMPDVYFVNMAIAGLIINALAPMYLLGLANTKWAIWNSNNEVYITLLILFNVSSLVTMYSTTLLSLDYYIERALPRTYMSSVYNTKHVCGFIWGGAMLTSFSSLLFYVCNHVSTKIIECSKMQNKEAADAIMVFIGYVVPAVAVLYALILILRIRKEATPLDQDTGRLDPSVHRLLIATVCTQFTLWTPYYVTLLVKSPGHSSCIISFFYSPHLFQSSTQTCYSISSCSCSLCAWPCTCGTSQDYLLHDNSTFLQQFDITTKCDGNHIGKEC", "length": 331, "header": "tr|A0A8V0ZWE1-1|A0A8V0ZRF1_CHICK Computationally mapped isoform of G protein-coupled receptor 146 OS=Gallus gallus OX=9031 GN=GPR146 PE=4 SV=1 CANONICAL=A0A8V0ZRF1-1" }, "locus": { "chromosome": "14", "start_pos": 2342263, "end_pos": 2338158, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054876.1", "url": "https://www.ensembl.org/id/ENSGALT00010054876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033174.1", "url": "https://www.ensembl.org/id/ENSGALP00010033174.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416456", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416456", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287APZ3-1", "protein_name": "G protein-coupled receptor 146", "gene_name": "GPR146", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWSCGPLNGSGGEDQLLCQHAQRALPALSLLYLLVGVPLGLGYNALLLLVNLHDPAGMTMPDVYFANMAVAGLVLGALAPAHLLGPGASGWAVWDLGSEVRVTLLVLFNVSALVALYSTALLGLDCYIERALPRSYMSSVYNTRHVCGFVWGGALLASFSSLLSYICSHVAARVAECSRMQDAQAADAILVLIGYLVPALAALYALVLIARVRKQATPLDQDAGGLDPAAHRLLVATVCTQFGLWTPHYLTLLGRTVLAARGKPVDGQHLGVLLLARDLSRLLAFCSSSTLPLLYRYINRSFPGKLQRLLKKMHRGHRSCSLDQAGAPPVTA", "length": 332 }, "evidence": [ { "id": "A0A8V0ZRF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9SYG6-1", "protein_name": "G protein-coupled receptor 146", "gene_name": "GPR146", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWSCPLNGTDGEDPLPCLHVQRALSALSLLYLLGGVPLGLGYNALLLLANLHDPGSMTMPDVYFANMAAAGLLLCALAPAHLLGPGAAGGAAWDLGSEVHVSLLVLFNVAALVTLYSTALLGLDCYIERALPRTYMSSVYNTRHVCGFVWGGALLAGFSSLLFHICSHVAARLVECSRMRDAAAADAIMLLVGYLVPGLAALYALALLVRVRKEDTPLDRDAGRPDPSAHRLLVATTCAQFGLWTPHYLMLLGRTVLAARGKPLDGHHVGTLLLAKDLSRFLAFASSAVVPLLYRHIDRNFPGKLRRLMKKLRRGHQNCSPDQAGAQPVTT", "length": 331 }, "evidence": [ { "id": "A0A8V0ZRF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZIS6-1", "protein_name": "G-protein coupled receptor 146", "gene_name": "Gpr146", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSCGPLNSTAWAEEPLCRNLRLGLWVLSLFYLGAGVPVGLGYNALLVLANLASKNSMTMPDVYFVNMAVAGLVLTALAPAYLLGPAHSRWALWSLSSEAHVTLLILFNVASLVTMYSTALLSLDYYIERALPRTYMASVYNTRHVCGFVWGGAVLTSFSSLLFYICSHVSSRIAECARMQNTEAADAILVLIGYVVPGLAVLYALALISRIGKEDTPLDQDTSRLDPSVHRLLVATVCTQFGLWTPYYLSLGHTVLVSRGRTVEGHYLGILQVAKDLAKFLAFSSSSVTPLLYRYINKAFPSKLRRLVKKIHCGRRHCSPDPAGIQQVMAQA", "length": 333 }, "evidence": [ { "id": "A0A8V0ZRF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96CH1-1", "protein_name": "G protein-coupled receptor 146", "gene_name": "GPR146", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWSCSWFNGTGLVEELPACQDLQLGLSLLSLLGLVVGVPVGLCYNALLVLANLHSKASMTMPDVYFVNMAVAGLVLSALAPVHLLGPPSSRWALWSVGGEVHVALQIPFNVSSLVAMYSTALLSLDHYIERALPRTYMASVYNTRHVCGFVWGGALLTSFSSLLFYICSHVSTRALECAKMQNAEAADATLVFIGYVVPALATLYALVLLSRVRREDTPLDRDTGRLEPSAHRLLVATVCTQFGLWTPHYLILLGHTVIISRGKPVDAHYLGLLHFVKDFSKLLAFSSSFVTPLLYRYMNQSFPSKLQRLMKKLPCGDRHCSPDHMGVQQVLA", "length": 333 }, "evidence": [ { "id": "A0A8V0ZRF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99LE2-1", "protein_name": "G protein-coupled receptor 146", "gene_name": "Gpr146", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWSCGPLNSTAWAEEPLCRNLRLGLWVLSLLYLGAGVPVSLGYNALLVLANLASKNTMTMPDVYFVNMAVAGLVLTALAPAYLLGPAHSRWALWSLSSEAHVTLLILFNVASLVTMYSTALLSLDYYIERALPRTYMASVYNTRHVCGFVWGGAVLTSFSSLLFYICSHVSSRIAECARMQNTEAADAILVLIGYVVPGLAVLYALALISRIGKEDTPLDQDTSRLDPSVHRLLVATVCTQFGLWTPYYLSLGHTVLTSRGRTVEGHYLGILQVAKDLAKFLAFSSSSVTPLLYRYINKAFPGKLRRLMKKMHCGRRHCSPDPSGIQQVMAQA", "length": 333 }, "evidence": [ { "id": "A0A8V0ZRF1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway", "id": "GO:0007193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007193", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1" } ], "pmid": "" }, { "name": "regulation of cholesterol biosynthetic process", "id": "GO:0045540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045540", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 296, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRD8-1", "uniprot_ac": "A0A8V0ZRD8", "uniprot_id": "A0A8V0ZRD8_CHICK", "mass": { "chemical_mass": 54477.0, "monoisotopic_mass": 54477.0 }, "refseq": { "ac": "XP_428853", "name": "keratin, type II cytoskeletal 80", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428853" }, "gene_names": [ { "name": "KRT80", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8" } ] }, { "name": "KRT80", "type": "synonym", "evidence": [ { "id": "XP_428853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428853" } ] } ], "protein_names": [ { "name": "Keratin 80", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8/entry#names_and_taxonomy" } ] }, { "name": "keratin, type II cytoskeletal 80", "type": "synonym", "evidence": [ { "id": "XP_428853", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428853" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052565.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_428853.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_428853", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428853" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KRT80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8", "locus": { "chromosome": "34", "start_pos": 2115202, "end_pos": 2099676, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024206", "url": "https://www.ensembl.org/id/ENSGALG00010024206" } ] } } ], "crossref": [ { "id": "A0A8V0ZRD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "431302", "url": "https://www.ncbi.nlm.nih.gov/gene/431302", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:431302", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431302", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSGMEYT", "url": "https://omabrowser.org/oma/group/CSGMEYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRD8", "url": "https://www.orthodb.org/?gene=A0A8V0ZRD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45616:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45616:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6805567", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6805567", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6809371", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6809371", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_428853", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_428853", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNLCKAFSSGSLCSWEASGRMSQGRAGSTSPDSLGHCSPSSVTSPSCGAPYGDGGYQSSSYLSIDGRLLAPVHLDIDTDFHAVREQEKEDIKLLNNQFVTLIEKVQCLEQQNKILTTRWNFLKDQDNSHSESDVKAIYDQYMSKMNQEMQALNYEQENLESELTEVLSTMDNFRSKYEDEIRLCSGMEYTFMELKKDLDASTLHRTELEVKLSGLQELMDLKKTIYEQELEELLTEIKDISVVLGIDNTCKLDLSRIVEEVRAQYEALALRSWEEAEALTRRKLNEGNTQSATYGGHLLDSRREIADLNIQIQKLRSCIVSQKSQCLYLEENIKEAGEHGEMALKDAKAKLVKLEEALQKSKEDMAHLVKEYQELMNIKLALDLEILTYRKLVEGEESSMESPIPTVISTIHSRPKHLSASTLRNSKLFARGTSSANGEMKLNGGNTKPLPSRSHSNNLAAPEADPYTCSARPKLSSLLTEECS", "length": 485, "header": "tr|A0A8V0ZRD8-1|A0A8V0ZRD8_CHICK Isoform 1 of Keratin 80 OS=Gallus gallus OX=9031 GN=KRT80 PE=4 SV=1 CANONICAL=A0A8V0ZRD8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8/entry#A0A8V0ZRD8-1", "sequence": { "sequence": "MTNLCKAFSSGSLCSWEASGRMSQGRAGSTSPDSLGHCSPSSVTSPSCGAPYGDGGYQSSSYLSIDGRLLAPVHLDIDTDFHAVREQEKEDIKLLNNQFVTLIEKVQCLEQQNKILTTRWNFLKDQDNSHSESDVKAIYDQYMSKMNQEMQALNYEQENLESELTEVLSTMDNFRSKYEDEIRLCSGMEYTFMELKKDLDASTLHRTELEVKLSGLQELMDLKKTIYEQELEELLTEIKDISVVLGIDNTCKLDLSRIVEEVRAQYEALALRSWEEAEALTRRKLNEGNTQSATYGGHLLDSRREIADLNIQIQKLRSCIVSQKSQCLYLEENIKEAGEHGEMALKDAKAKLVKLEEALQKSKEDMAHLVKEYQELMNIKLALDLEILTYRKLVEGEESSMESPIPTVISTIHSRPKHLSASTLRNSKLFARGTSSANGEMKLNGGNTKPLPSRSHSNNLAAPEADPYTCSARPKLSSLLTEECS", "length": 485, "header": "tr|A0A8V0ZRD8-1|A0A8V0ZRD8_CHICK Isoform 1 of Keratin 80 OS=Gallus gallus OX=9031 GN=KRT80 PE=4 SV=1 CANONICAL=A0A8V0ZRD8-1" }, "locus": { "chromosome": "34", "start_pos": 2114002, "end_pos": 2100000, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059061.1", "url": "https://www.ensembl.org/id/ENSGALT00010059061.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036025.1", "url": "https://www.ensembl.org/id/ENSGALP00010036025.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:431302", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:431302", "resource": "KEGG Pathway" }, { "id": "R-GGA-6805567", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6805567", "resource": "Reactome", "description": "Keratinization" }, { "id": "R-GGA-6809371", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6809371", "resource": "Reactome", "description": "Formation of the cornified envelope" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZL11-1", "protein_name": "Keratin 80", "gene_name": "KRT80", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MACRSCVVGFSSLSSCEVTPAGGPRPEASGWGSCGAPGPSFSSSSLTGCWAAGTVPKVTVNSSLLEPLDLKVDPAIQQQKHQEKEEMKALNDKFASLIGKVQALEQRNQLLETRWCFLQSQDSAAFDLGHLYKDYQGRLQEELRKVSQERSQLEANLMQMLEKVEEFRIRYEDELSKRTDLEFTFVQLKKDLDTECLRRTELETKLKDLQSFVELMKSIYEQELKDLAAQVKDVSVTVGMDSRCHLDLSGIVEEVKAQYDAIAARSLEEAEAYSRSQLEERAACSAELGNSLQSSRREIADLNVRIQKLRSQILSIKSHCLKLEENIKAAEEQGELAFQDAKAKLAQLEDALQRAKKDMAQQLREYQELMNVKLALDVEIATYRKLVEGEESRMDLPSATMVSAVKSRSRTATTKSGLSRAPFRRRKNRKGPVIKITEMSEKFLSQESEVSE", "length": 452 }, "evidence": [ { "id": "A0A8V0ZRD8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRD8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3II07-1", "protein_name": "Keratin, type II cytoskeletal 80", "gene_name": "Krt80", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAYRSCVVGFSSLSGCEVTSAGRLQPGTSGWGSCGLPGPGFSSRSLTSCRPAGIIPKVTVNSSLLVPLDLKVDPAVQQQKNQEKEEMKVLNDKFASLIGKVQALEQRNQLLETRWSFLQGQGTTTFDLSHHYETFQGSLQEELRKVSQERGQLEANLLQVLEKVEEFRIRYEDEISKRTDLEFTFVQLKKDLDAECLRRTELETKLKGLQSFVELMRTVYEQELKDLTAQVKDVSVTVGLDSRCHIDLSGIVEEVKAQYDAIAARSLEEAEAYSRSQLEERAARSAEFGSSLQSSRCEIADLNVRIQKLRSQILSIKSHCLKLEENIKVAEEQGELAFQDAKDKLAQLEAALQKAKQDMARQLREYQDLMNTKLALDIEIATYRKLVEGEESRMDLPSATVVSAVQSRCRTTASKSGLSKTPSRKKKNRRGPVIKITEMSEKYLSQESEASE", "length": 452 }, "evidence": [ { "id": "A0A8V0ZRD8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRD8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0VBK2-1", "protein_name": "Keratin, type II cytoskeletal 80", "gene_name": "Krt80", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAYRSCVVGFSSLSGCEMTPAGSPQPGTSGWGSCGLPGPGFSSRSLTSCRPAGTIPKVTVNPSLLVPLDLKVDPAVQQQKNQEKEEMKALNDKFASLIGKVQALEQRNQLLETRWSFLQGQGSATFDLSHHYETFQGRLQEELRKVSQERGQLEANLLQVLEKVEEFRVRYEDEISKRTDLEFTFVQLKKDLDAECLRRTELETKLKGLQGFLELMRTVYEQELKDLTAQVKDVSVTVGLDSRCHIDLSGIVEEVKAQYDAIAARSLEEAEAYSRSQLEERAARSAEFGNSLQSSRCEIADLNVRIQKLRSQIVSVKSHCLKLEENIKVAEEQGELAFQDAKDKMAQLENALQKAKQDMARQLREYQDLMNTKLALDIEIATYHKLMEGEESRMDLPSATVVSTVKSGCRTTASKSGLTKTSSRKKKNRRGPVIKITEMSEKYLSQESEASE", "length": 452 }, "evidence": [ { "id": "A0A8V0ZRD8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRD8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6IMF1-1", "protein_name": "Keratin, type II cytoskeletal 80", "gene_name": "Krt80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAYRSCVVGFSSHSGCEVTPAGSSQPGTSGWGSCGLPGPGFSSRSLTSCRPAGVIPKVTVNPSLLVPLDLKVDPAVQQQKNQEKEEMKVLNDKFASLIGKVQALEQRNQLLETRWGFLQGQGSATFDLSHHYETFQGRLQEELRKVSQERGQLEASLLQVLEKVEEFRVRYEDEISKRTDLEFTFVQLKKDLDAECLRRTELETKLKGLQGFVELMRTVYEQELKDLTAQVKDVSVTVGLDSRCHIDLSGIVEEVKAQYDAIAARSLEEAEAYSRSQLEERAARSAEFGNSLQSSRCEIADLNVRIQKLRSQIVSVKSHCLKLEENIKVAEEQGELAFQDAKDKMAQLEAALQKAKQDMARQLREYQDLMNTKLALDIEIATYHKLMEGEESRMDLPSTTVVSAVQSRCRTTASKSGLSKTPSRKKKNRGGPVIKITEMSEKYLSQESEASE", "length": 452 }, "evidence": [ { "id": "A0A8V0ZRD8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRD8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6KB66-1", "protein_name": "Keratin, type II cytoskeletal 80", "gene_name": "KRT80", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACRSCVVGFSSLSSCEVTPVGSPRPGTSGWDSCRAPGPGFSSRSLTGCWSAGTISKVTVNPGLLVPLDVKLDPAVQQLKNQEKEEMKALNDKFASLIGKVQALEQRNQLLETRWSFLQGQDSAIFDLGHLYEEYQGRLQEELRKVSQERGQLEANLLQVLEKVEEFRIRYEDEISKRTDMEFTFVQLKKDLDAECLHRTELETKLKSLESFVELMKTIYEQELKDLAAQVKDVSVTVGMDSRCHIDLSGIVEEVKAQYDAVAARSLEEAEAYSRSQLEEQAARSAEYGSSLQSSRSEIADLNVRIQKLRSQILSVKSHCLKLEENIKTAEEQGELAFQDAKTKLAQLEAALQQAKQDMARQLRKYQELMNVKLALDIEIATYRKLVEGEEGRMDSPSATVVSAVQSRCKTAASRSGLSKAPSRKKKGSKGPVIKITEMSEKYFSQESEVSE", "length": 452 }, "evidence": [ { "id": "A0A8V0ZRD8", "url": "https://omabrowser.org/oma/group/A0A8V0ZRD8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "keratinization", "id": "GO:0031424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of skin epidermis", "id": "GO:0030280", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030280", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRD8" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 401, "start_aa": "Glu", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRE1-1", "uniprot_ac": "A0A8V0ZRE1", "uniprot_id": "A0A8V0ZRE1_CHICK", "mass": { "chemical_mass": 142980.0, "monoisotopic_mass": 142980.0 }, "refseq": { "ac": "XP_422397", "name": "cilia- and flagella-associated protein 57", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422397" }, "gene_names": [ { "name": "CFAP57", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE1" } ] }, { "name": "CFAP57", "type": "synonym", "evidence": [ { "id": "XP_422397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422397" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 57", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE1/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 57", "type": "synonym", "evidence": [ { "id": "XP_422397", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422397" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052539.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422397.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422397" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP57", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE1", "locus": { "chromosome": "8", "start_pos": 19330873, "end_pos": 19308585, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022534", "url": "https://www.ensembl.org/id/ENSGALG00010022534" } ] } } ], "crossref": [ { "id": "A0A8V0ZRE1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRE1", "database": "AlphaFoldDB", "categories": [] }, { "id": "424559", "url": "https://www.ncbi.nlm.nih.gov/gene/424559", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FPHCNAV", "url": "https://omabrowser.org/oma/group/FPHCNAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRE1", "url": "https://www.orthodb.org/?gene=A0A8V0ZRE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32215", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32215", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32215:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32215:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_422397", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422397", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVVEAQPAAVFGCRPGVSGGICFLEEQLVLYAAGAACAQFHTEQRWHKFIPGREKSRGVRALAVSRSRRYLAVSEMAEEEPALTVYELTAEPPRRRRTLSAAELPARETVALAFSPDGRYLAAATGPPEAQLALWLWEKQRLLAVVRLEAADIGVCQVSFSPQDNAQVCVTGNGFFKLFKYSEGTLKQINLQKGEPQNYLCHAWLSEEEIICGTATGKLFLFESGELLWQRDVEYRKPPKELEEGTRAKDYVSSSDVSGEPTSEDSGSLQDSLPQISAVAAYSKGFACSSSPGVVLLFEKTNKEVYKESQEIWLPRDLFTTVPKLSGRQDITCICFSPSEEVLVVSTTKNQLYMFTMPSADYLKEESSHFEYLHFPLHSASITGLDVCIRRPIVATCSLDKSVRVWNYKTNTLELCKEFWEEAYTVALHPTGLFCLVGFSDKLRFISLLYEDMHVFKDFPVRECRECSFSNGGHLFAAVNGNVIQIYSCTTFENTNNLKGHSGKIHAVKWSADDSKCFSCDTHGAVYEWNLSTGKREMECVLTSCIYSSIALHSDSKIIFAVGSDQTLKEISESSVHHEVPAFDVVYTAVAVSHSGDMVFVGTSLGTVRSMKYPLPLCRDFNEYQAHAGAITKMSVTNDDLFLLTASEDGSIFFWKVCSKKGKILKREKEFEYAEEVLIMKSDIEEKSRTILDLQIRVKELQIENDYQLRLKDMSCYEKIKELEETFTQELESLKNKHQILQAEKDNQEMQHQLQLSELMNKHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQEEYEKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDLHNCVGFIQDYKKLKAGIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEINDLRQELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNETLSSPAVLRLNAQKENEKIIEMQLLEIQHLRDQVQEKGQGLEAQPLLYGMLPKLNLERSHKMHQH", "length": 1238, "header": "tr|A0A8V0ZRE1-1|A0A8V0ZRE1_CHICK Isoform 1 of Cilia and flagella associated protein 57 OS=Gallus gallus OX=9031 GN=CFAP57 PE=1 SV=1 CANONICAL=A0A8V0ZRE1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE1/entry#A0A8V0ZRE1-1", "sequence": { "sequence": "MSVVEAQPAAVFGCRPGVSGGICFLEEQLVLYAAGAACAQFHTEQRWHKFIPGREKSRGVRALAVSRSRRYLAVSEMAEEEPALTVYELTAEPPRRRRTLSAAELPARETVALAFSPDGRYLAAATGPPEAQLALWLWEKQRLLAVVRLEAADIGVCQVSFSPQDNAQVCVTGNGFFKLFKYSEGTLKQINLQKGEPQNYLCHAWLSEEEIICGTATGKLFLFESGELLWQRDVEYRKPPKELEEGTRAKDYVSSSDVSGEPTSEDSGSLQDSLPQISAVAAYSKGFACSSSPGVVLLFEKTNKEVYKESQEIWLPRDLFTTVPKLSGRQDITCICFSPSEEVLVVSTTKNQLYMFTMPSADYLKEESSHFEYLHFPLHSASITGLDVCIRRPIVATCSLDKSVRVWNYKTNTLELCKEFWEEAYTVALHPTGLFCLVGFSDKLRFISLLYEDMHVFKDFPVRECRECSFSNGGHLFAAVNGNVIQIYSCTTFENTNNLKGHSGKIHAVKWSADDSKCFSCDTHGAVYEWNLSTGKREMECVLTSCIYSSIALHSDSKIIFAVGSDQTLKEISESSVHHEVPAFDVVYTAVAVSHSGDMVFVGTSLGTVRSMKYPLPLCRDFNEYQAHAGAITKMSVTNDDLFLLTASEDGSIFFWKVCSKKGKILKREKEFEYAEEVLIMKSDIEEKSRTILDLQIRVKELQIENDYQLRLKDMSCYEKIKELEETFTQELESLKNKHQILQAEKDNQEMQHQLQLSELMNKHAKEMRDLESDSNQKLLMENEKYQELQVDSQRMQEEYEKQLHNLQESKNRTVEELTDYYEEKLNEKSLLLEEAEEDMRQQLQAHEEIKKQIEEDEDREIQDIKIKYERWLIEEKESNLQLKGEIGVMNKRLNSLQKELKERNNDIEDMKLEQQNLQGIIKSLEKDISMLNTNIEKRTNTIQEKEKHIYDLKKKNQELEKFKFVLDHRIEQFKKQIESRENDIKIMQKQIHEMERELEQLHKENTQLKLNITQLQQKLKATDNELHKERQKKQNMEALIKRFKMDLHNCVGFIQDYKKLKAGIRELYTKYVQQLEMVEMEEVDTDLQQEYMRQREYLERNLAALKKKVVKDQEVHQAAYTRIMQENVSLIKEINDLRQELTVAHTQVHDLQSALKLTKKKQAIQDTAPSNETLSSPAVLRLNAQKENEKIIEMQLLEIQHLRDQVQEKGQGLEAQPLLYGMLPKLNLERSHKMHQH", "length": 1238, "header": "tr|A0A8V0ZRE1-1|A0A8V0ZRE1_CHICK Isoform 1 of Cilia and flagella associated protein 57 OS=Gallus gallus OX=9031 GN=CFAP57 PE=1 SV=1 CANONICAL=A0A8V0ZRE1-1" }, "locus": { "chromosome": "8", "start_pos": 19330620, "end_pos": 19308620, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054853.1", "url": "https://www.ensembl.org/id/ENSGALT00010054853.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033156.1", "url": "https://www.ensembl.org/id/ENSGALP00010033156.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AFR3-1", "protein_name": "Cilia- and flagella-associated protein 57", "gene_name": "Cfap57", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIQELLWRLGVPGLLRLFRKNTCGSLRCIVIQSREARGTMSTVVAQSLHVFGLRSHVTNNIFFFDEQIVIFPSGNHCVKYNLDQKWQKFIAGSDKSQGMLALSISPNRRYLAISETVQDKPIITIYELSSIPCRKRKVLNNFEFQVQKFTSMAFSPDSKYLLTQTSPPESNLVYWLWEKQKVMAVIKADIQNNPIYQVSINPQDNTQVCITGNGIFKILRFAEGTLKQTNFQRGESPNCLAHSWVSEDRIIVGTDTGKLFLFESGDQRWETNIMVKEPTSSRSLDIIHESESLVEFPPPSSPASSIEQMSTTTYTQQVVLPQVFAIAAYSKGFACSAGPGRVLLFEKVEEKDFYRESREIRIPVDPQSNDPSQSDKQDVLCLCFSPSEETLVASTSKNQLYSITMSLTEISKGEAAHFEYLLYPLHSASITGLATCIRKPLIATCSLDRSVRIWNYESNTLELYKEYQEEAYTVSLHPSGHYIVVGFADKLRLMNLLIDDIRSFKEYSVRGCKECAFSNGGHLFAAVNGNVIHIFTTTNLENINNLKGHTGKIRSLVWNTDDSKLISAGTDGAVYEWNLSTGKRETECVLKVCSYNSVTISPDGKVIFAVGSDQTLKEIADSLILREIPAFDVVYTAITISHSGRMIFVGTSVGTIRAMKYPLPLQREFNEYQAHAGPVTKILLTFDDQFLLTVSEDGCLFTWKVFDKEGRGIKREREVGFAEEVLVTKTDMEEKAQIMLELKTRVEELKMENEYQLRLKDMNYSEKIKELTDKFIQEMESLKTKNQVLKTEKEKQDISHREHLEDLIERQSRELQDLECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTGLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYERKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIELLKTEQVKLQGVIRSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPRENEIKVMKEQIQEMEDELERFHKQNTQLELNITELLQKLRATDQEMRKEQQKERDLEALVRRFKTDLHNCVSYIQEPRQLKEKIRALFEKYVQRADMVEIAGLNSDLQQEYARQREHLERNLATLKKKVVKEGELHRADYVRIMQENVSLIKEINELRRELKLTRSQIYDLESALKVSKKTRAQEAPESVLTKDVVGTSSTMRLNEQEETGRIIEMQRLEIRRLRDQIQEQEQVPGFHTIAGVRLPSLVDSDVDFEVHTK", "length": 1288 }, "evidence": [ { "id": "A0A8V0ZRE1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRE1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HFH7-1", "protein_name": "Cilia- and flagella-associated protein 57", "gene_name": "Cfap57", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSTVVAQALHVFGLRSYVANNVFFFDEQIIIFPSGNHCVKYNVDQKWQKFIPGSDKSQGMLALAISPNRRYLAISETVLERPTITIYELSSIPCRKRKVLNNFDFQVQKFISMAFSPDSKYLLTQTSPPESNLVYWLWEKQKVMAMIRSDVQNNPIYQVSINPQDNTQVCVTGSGVFKLLRFTEGTLKQTNFQRGESPNYLAHSWVSDDRLIVGTDTGKLFLFESGDQRWETSIMVKEPTSSRSLEIIHESESLIEFPQPSSPVPSFEQIVATTYPSHMTMPQVFAIAAYSKGFACSAGPGRVLLFEKATEEKDFYRESREIRIPTDPQSNDPSQSDKQDVLCLCFSPSEETLIASTSKNQLYTITMSLTEISKGEPAHFEYLMYPLHSASITGLSTCIRKPLIATCSLDHSIRIWNYESNTLELFKEYQEEAYTITLHPSGHFIVVGFADKLRLMNLLIDDIRAFKEYSVRGCKECSFSNGGHLFAAVNGNVIHIFTTTSLENVGNLKGHTGKIRSIAWNFDDSRLISAGTDGAVYEWNLSTGKRETECVLKSCSYNSVAVSPDAKIIFAVGSDQTLKEISDSLILREISAFDVVYTAITISHSGRMMFVGTSVGTIRAMKYPLPLQKEFNEYQAHAGPINKMMLTFDDQYLLTVADDGCLFTWRVFDKDGRGIKREREVGFAEEVLVTKTDMEEKAQVMLELKTRVEELKMENEYQLRLKDMNYSEKIKELTDKFIQEMESLKTKNQVLKTEKEKQDIFHRERIEDLMEKQGRELQDLECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTSLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYEKKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIENLKAEQMKLQGVIKSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPRENEIKVMKEQIQEMEAELERFHKQNTQLELNISELLQKLRATDQEMRKEQQKERDLEALVRRFKTDLHNCVAYIQEPRLLKEKIRDLFEKYVQRADMVEIAGLNSDLQQEYARQREHLERNLATLKKKVVKEGELHRAGYVRIMQENVSLIKEINELRRELKLTRSQIYDLESALKLSKKLRAQDVPETVVSKDIPSVSTTMRLNEKEETGRIIEMQRLEIRRLRDQIQEQEQVPGFHTIAGVRLPSIVESEVDLEVHSK", "length": 1250 }, "evidence": [ { "id": "A0A8V0ZRE1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRE1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q96MR6-1", "protein_name": "Cilia- and flagella-associated protein 57", "gene_name": "CFAP57", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAVVAQTLHVFGLRSHVANNIFYFDEQIIIFPSGNHCVKYNVDQKWQKFIPGSEKSQGMLALSISPNRRYLAISETVQEKPAITIYELSSIPCRKRKVLNNFDFQVQKFISMAFSPDSKYLLAQTSPPESNLVYWLWEKQKVMAIVRIDTQNNPVYQVSFSPQDNTQVCVTGNGMFKLLRFAEGTLKQTSFQRGEPQNYLAHTWVADDKIVVGTDTGKLFLFESGDQRWETSIMVKEPTNGSKSLDVIQESESLIEFPPVSSPLPSYEQMVAASSHSQMSMPQVFAIAAYSKGFACSAGPGRVLLFEKMEEKDFYRESREIRIPVDPQSNDPSQSDKQDVLCLCFSPSEETLVASTSKNQLYSITMSLTEISKGEPAHFEYLMYPLHSAPITGLATCIRKPLIATCSLDRSIRLWNYETNTLELFKEYQEEAYSISLHPSGHFIVVGFADKLRLMNLLIDDIRSFKEYSVRGCGECSFSNGGHLFAAVNGNVIHVYTTTSLENISSLKGHTGKIRSIVWNADDSKLISGGTDGAVYEWNLSTGKRETECVLKSCSYNCVTVSPDAKIIFAVGSDHTLKEIADSLILREISAFDVTYTAIVISHSGRMMFVGTSVGTIRAMKYPLPLQKEFNEYQAHAGPITKMLLTFDDQFLLTAAEDGCLFTWKVFDKDGRGIKREREVGFAEEVLVTKTDMEEKAQVMLELKTRVEELKMENEYQLRLKDMNYSEKIKELTDKFIQEMESLKTKNQVLRTEKEKQDVYHHEHIEDLLDKQSRELQDMECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTTLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYEKKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIETLKGEQMKLQGVIKSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELGKFKFVLDYKIKELKKQIEPRENEIRVMKEQIQEMEAELENFHKQNTQLELNITELWQKLRATDQEMRRERQKERDLEALVKRFKTDLHNCVAYIQEPRLLKEKVRGLFEKYVQRADMVEIAGLNTDLQQEYTRQREHLERNLATLKKKVVKEGELHRTDYVRIMQENVSLIKEINELRRELKFTRSQVYDLEAALKLTKKVRPQEVSETEPSRDMLSTAPTARLNEQEETGRIIEMQRLEIQRLRDQIQEQEQVTGFHTLAGVRLPSLSNSEVDLEVKTN", "length": 1250 }, "evidence": [ { "id": "A0A8V0ZRE1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRE1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D180-1", "protein_name": "Cilia- and flagella-associated protein 57", "gene_name": "Cfap57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTVVAQALHVFGLRPHVTNNVFFFDEQIIIFPSGNHCVKYNIDQKWQKFIAGSDKSQGMLALAISPNRRYLAISETVQEKPAVTIYELSSIPCRKRKVLNNFDFQVQKFTSMAFSPDSKYLLTQTSPPDSNLVYWLWEKQKVMAIIKADSQNNPIYQVSISSQDNSQVCITGSGVFKLLRFAEGTLKQINFQRGESSNYLAHAWVSEDRVIVGTDTGKLFLFESGDQRWETSIMVKESTSSRSLEVIQESESLIEFPPLSSPVSSVERMDITTNTQQQAMPQVFAIAAYSKGFACSAGPGRVLLFEKVEEKDFYRESREIRIPTDQQSNDPSQSDKQDVLCLCFSPSEETLIASTNKNQLYSITMSLTEISKGEAAHFEYLLYPLHSASITGLDTCIRKPLIATCSLDRSVRIWNYESNTLELYKEYQEEAYTVSLHPSGHYIVVGFADKLRLMNLLIDDIRPFKEYSVRGCKECSFSNGGHLFAAVNGNVIHIFTTTSLENINILKGHTGKIRSLVWNLDDSKLVSAGTDGAVYEWNLSTGKRETECVLKSCSYNSVTTSPDAKVIFAVGSDQTLKEISDSLILREIPAFDVIYTSITISHSGRMIFVGTSVGTIRAMKYPLSLQKEYNEYQAHAGPVMKMLLTFDDQFLLTVGEDGCLFTWKVFDKDGRGIKREREVGFAEEVLVTKTDMEEKAQIMLELKTRVEELKMENEYQLRLKDMNYTEKIKELTDKFIQEMESLKTKNQVLKTEKEKQDISHRERLEELVDKQTRELQDLECCNNQKLLLEYEKYQELQLKSQRMQEEYEKQLRDNDETKSQALEELTEFYEAKLQEKTGLLEEAQEDVRQQLREFEETKKQIEEDEDREIQDIKTKYERKLRDEKESNLRLKGETGIMRKKFSSLQKEIEERTNDIELLKSEQMKLQGIIRSLEKDIQGLKREIQERDETIQDKEKRIYDLKKKNQELEKFKFVLDYKIKELKKQIEPRENEIKVMKEQIQEMEAELERFHKQNTQLELNITELLQKLRATDQEMRKEQQKERDLEALVRRFKTDLHNCVAYIQEPGLLKEKIRGLFEKYVQRADMVEIAGLNSDLQQEYARQREHLERNLATLKKKVIKEGELHRTDYVRIMQENVSLIKEINELRRELKLTRSQIYDLESALKVSKKTRSQEVPESVISKDVVGSTSTMRLNEQEETGRIIEMQRLEIRRLRDQIQEQEQVPGFHTIAGVRLPSIVDSDVDFEVHTK", "length": 1249 }, "evidence": [ { "id": "A0A8V0ZRE1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRE1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W235-1", "protein_name": "Testes of unusual size", "gene_name": "tous", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDEANKEDVKRASLSNSTVTIRPRLIYGLRSDVIGNIHFNLTKEVIYPVEGVLAFHDYVQNKQRFLRLPEDTRPEVISISSHRKLLAVVERHSKNGRYISIYELATLKKRRHLELPSNHRNAEIQQMIFTNDSRSVALITRPPEETLIMLVLDKTSTVIEGRATIPGSHGGAECIAGNPNDCNFMAVGGERTLLLMSKSERGFSISNNLKVKYRVTSMAFLSLDLLMIGTSDDQLILVENGEQKLAQKASDADTVDLMIDQEVFDRDKELQEQRFLPTQAVSLPDRRVLCMTAFPKGFAYIIFNRAFVFERVSKFKFERKTILTVPTNLYAEHMYQILNLAIDHKQETVIVTTSHCQIYVGILIVPETLKTKQLKFEPLGVLIHTGEIIAMSVCAWKPIIMTASRDQTIRIWNYETALVELVRKFQVDVNIVELSLTGQMAAIGFSDQLRITQIFMDDLNIVKTYNFPHCNAVRYSNFGHMMAAAYDNNIAITSVYKLDVLINLKGHNGIVLSVAWSRTDKFLISGGAEGAIYLWDIETGARLQEIVQKGTEYVTISCSTNDPLTIYAGTSIGTIREFQDSTLMREITIPSRTKGSVSDVCLARSDLIMFVADHEGNLFNMQLPFLEAGGGTFTNFRFFDGPVNKLRFSYDGTLLFAISNKGTLAIWAMDNIEGKVPYMDQDLMRSQEVLIPRSQLNDKIEQIANLELRLKQQAEEFQYQLSQNEIFDGQQLQEVHRSYCSALEELKELNNEIEARHTEEMNHITFQINSIREEHRIQLDTLATQYSERMLIEYQKFTNLRENMLELRESYEDKLKNSTGTLQDTVEALENNYKQQLNERKELIRDLMKEMQDKKAEFIEYCREVELENDRNMVSTQTEYENKLTTERNETQMWRGKAGVLQKKFESQSREIDNLLEEVEILKEEHHKSQRNIQKQMRNIEDLQKDIADRDYAINGKEKRIQDLLHKNQELDKYKQVLGHKIAELKAQIEPREFQINDKRKHIIEMEAELEGLNQNNVQLELQLKEMRDKYLSNVAELRTERHRAKASRECLHSICSDIYYVAGEINSAEALKKAVKELFRKHASDDELKRFVTLDAEVRDEFMRQRRQIENVLDRYKSVAEDKSVQKKYDKLFKENVILIEEIEKLNETNKMLRSKVKEDLRRSTKTIHK", "length": 1171 }, "evidence": [ { "id": "A0A8V0ZRE1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRE1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRE1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1012, "end_pos": 1014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1128, "end_pos": 1130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1172, "end_pos": 1174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRE1" }, { "id": "PF23414", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like second beta-propeller", "eco_id": "ECO_0000259", "start_pos": 384, "end_pos": 658, "start_aa": "Thr", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1012, "end_pos": 1014 }, { "start_pos": 1128, "end_pos": 1130 }, { "start_pos": 1172, "end_pos": 1174 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 812, "end_pos": 814 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRF5-1", "uniprot_ac": "A0A8V0ZRF5", "uniprot_id": "A0A8V0ZRF5_CHICK", "mass": { "chemical_mass": 85262.0, "monoisotopic_mass": 85262.0 }, "refseq": { "ac": "XP_004943820", "name": "leucine-rich repeat-containing protein 49 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943820" }, "gene_names": [ { "name": "LRRC49", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF5" } ] }, { "name": "LRRC49", "type": "synonym", "evidence": [ { "id": "XP_004943820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943820" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 49", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF5/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 49 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_004943820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943820" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004943820.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004943820", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943820" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF5", "locus": { "chromosome": "10", "start_pos": 6315868, "end_pos": 6275621, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022711", "url": "https://www.ensembl.org/id/ENSGALG00010022711" } ] } } ], "crossref": [ { "id": "A0A8V0ZRF5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "415393", "url": "https://www.ncbi.nlm.nih.gov/gene/415393", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415393", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415393", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRINKDQ", "url": "https://omabrowser.org/oma/group/FRINKDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRF5", "url": "https://www.orthodb.org/?gene=A0A8V0ZRF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZS80", "url": "https://www.orthodb.org/?gene=A0A8V0ZS80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45973", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45973", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45973:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45973:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004943820", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004943820", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS80", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZS80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZS80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPSKCRPGRGSRAAPGPAGSCGLQLLIQASAIPSKSKPFDFKINKEPPSLHNRLLQHDLEKNYSGRQGDPRVLSPLVRNKQLYLPVPSTLTELSGLEFKQSTGSLSGFGESSIHAKPRSRQSSHSITSHVSDNTHFGSSSSITFPVLQRTAEEKILNSDRLTLERQKLTVCPVIDGEDHLRLLNFQHNFITRIQNISNLQHLVFLDLYDNQIEEISGLSTLRSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENINHLSELRVLNLARNLLSIVENLNGLDSLTELNLRHNQVSAIKDVDTLPRLQRLFLSFNNISSFEDILCLADSSSLSDITLDGNPIAQETWYKHTVLHHMMQLRQLDMKRITEEERRMASVAARKEEERKRESHKQSLLKEKKRLTICNIARQWEIQQNRTDLVASLSQDKDNQPCPINGSAAYVFPEESRSLDTILNNAVQGLSVLESHLVELEGDTLYLYGSGALECLDRNWSVQTAGTIVTVSFVFIEFDEIVQVLTKLKIKFPNSVHLKFKETNLVALQQLNALAQLHRMEQLTVDPQGNPVVNFTLWKYYVLFRLNHFNLQKINGIEVTQDDVVMAERLFGILAYVASSELPRYRLLSSFGESGMKQLSYPLEGKGKKSGTGNEESGDNRRAGRESSTRATLNYVTKDFHMEKLEEIKERKTFCQTYVKNLVKEAADIHMKNESLQKLWPQMFIELVRDAVIEIRNKNSFMKLSLQRITDQKQ", "length": 750, "header": "tr|A0A8V0ZRF5-1|A0A8V0ZRF5_CHICK Isoform 1 of Leucine rich repeat containing 49 OS=Gallus gallus OX=9031 GN=LRRC49 PE=4 SV=1 CANONICAL=A0A8V0ZRF5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF5/entry#A0A8V0ZRF5-1", "sequence": { "sequence": "MVPSKCRPGRGSRAAPGPAGSCGLQLLIQASAIPSKSKPFDFKINKEPPSLHNRLLQHDLEKNYSGRQGDPRVLSPLVRNKQLYLPVPSTLTELSGLEFKQSTGSLSGFGESSIHAKPRSRQSSHSITSHVSDNTHFGSSSSITFPVLQRTAEEKILNSDRLTLERQKLTVCPVIDGEDHLRLLNFQHNFITRIQNISNLQHLVFLDLYDNQIEEISGLSTLRSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENINHLSELRVLNLARNLLSIVENLNGLDSLTELNLRHNQVSAIKDVDTLPRLQRLFLSFNNISSFEDILCLADSSSLSDITLDGNPIAQETWYKHTVLHHMMQLRQLDMKRITEEERRMASVAARKEEERKRESHKQSLLKEKKRLTICNIARQWEIQQNRTDLVASLSQDKDNQPCPINGSAAYVFPEESRSLDTILNNAVQGLSVLESHLVELEGDTLYLYGSGALECLDRNWSVQTAGTIVTVSFVFIEFDEIVQVLTKLKIKFPNSVHLKFKETNLVALQQLNALAQLHRMEQLTVDPQGNPVVNFTLWKYYVLFRLNHFNLQKINGIEVTQDDVVMAERLFGILAYVASSELPRYRLLSSFGESGMKQLSYPLEGKGKKSGTGNEESGDNRRAGRESSTRATLNYVTKDFHMEKLEEIKERKTFCQTYVKNLVKEAADIHMKNESLQKLWPQMFIELVRDAVIEIRNKNSFMKLSLQRITDQKQ", "length": 750, "header": "tr|A0A8V0ZRF5-1|A0A8V0ZRF5_CHICK Isoform 1 of Leucine rich repeat containing 49 OS=Gallus gallus OX=9031 GN=LRRC49 PE=4 SV=1 CANONICAL=A0A8V0ZRF5-1" }, "locus": { "chromosome": "10", "start_pos": 6314669, "end_pos": 6275796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055227.1", "url": "https://www.ensembl.org/id/ENSGALT00010055227.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033412.1", "url": "https://www.ensembl.org/id/ENSGALP00010033412.1" } ] } }, { "isoform_ac": "A0A8V0ZS80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF5/entry#A0A8V0ZS80-1", "sequence": { "sequence": "MVPSKCRPGRGSRAAPGPFDFKINKEPPSLHNRLLQHDLEKNYSGRQGDPRVLSPLVRNKQLYLPVPSTLTELSGLEFKQSTGSLSGFGESSIHAKPRSRQSSHSITSHVSDNTHFGSSSSITFPVLQRTAEEKILNSDRLTLERQKLTVCPVIDGEDHLRLLNFQHNFITRIQNISNLQHLVFLDLYDNQIEEISGLSTLRSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENINHLSELRVLNLARNLLSIVENLNGLDSLTELNLRHNQVSAIKDVDTLPRLQRLFLSFNNISSFEDILCLADSSSLSDITLDGNPIAQETWYKHTVLHHMMQLRQLDMKRITEEERRMASVAARKEEERKRESHKQSLLKEKKRLTICNIARQWEIQQNRTDLVASLSQDKDNQPCPINGSAAYVFPEESRSLDTILNNAVQGLSVLESHLVELEGDTLYLYGSGALECLDRNWSVQTAGTIVTVSFVFIEFDEIVQVLTKLKIKFPNSVHLKFKETNLVALQQLNALAQLHRMEQLTVDPQGNPVVNFTLWKYYVLFRLNHFNLQKINGIEVTQDDVVMAERLFGILAYVASSELPRYRLLSSFGESGMKQLSYPLEGKGKKSGTGNEESGDNRRAGRESSTRATLNYVTKDFHMEKLEEIKERKTFCQTYVKNLVKEAADIHMKNESLQKLWPQMFIELVRDAVIEIRNKNSFMKLSLQRITDQKQ", "length": 729, "header": "tr|A0A8V0ZS80-1|A0A8V0ZRF5_CHICK Computationally mapped isoform of Leucine rich repeat containing 49 OS=Gallus gallus OX=9031 GN=LRRC49 PE=4 SV=1 CANONICAL=A0A8V0ZRF5-1" }, "locus": { "chromosome": "10", "start_pos": 6314669, "end_pos": 6275796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055219.1", "url": "https://www.ensembl.org/id/ENSGALT00010055219.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033406.1", "url": "https://www.ensembl.org/id/ENSGALP00010033406.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415393", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415393", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N514-1", "protein_name": "Leucine-rich repeat-containing protein 49", "gene_name": "LRRC49", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIPGKYRSVSGRAASNVNCGLHLVIQTSSLPEKNKVEFKLNRETPSFPGRLLQHDLERNYSSRQGDGRVISPSPHNKSSCISSTTNVTELCGLEMKAATSSLSAFGDSSIQTPSKSRIRQGCHSAGPNVSGDHINLVSSSMPSFPILQRSSEEKILYSDRLTLERQKLTVCPIIDGEEHLRLLNFQHNSITQIQNISNLQRLIFLDLYDNQIEEISGLSTLRSLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENVNHLCDLRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNISTFESVCCLADSTSLSDITFDGNPIAQESWYKHTILQNMMQLRQLDMKRITEEERRMASVVAKKEEEKKRESQKQSLLKEKKRLTINNVARKWDLQQHRITSIAINQDRRDSDSQDHCQNDGSTVSTFPEEAGSLDSGLTSALQDLSVTDTHLVEVDGDTLSLYGSGALECLDRNWSVQTAGMVTTVSFTFIEFDEIVQVLPKLKIKFPNSLHLKFKETNLVMLQQFNALAQLRRVDQLTIDPQGNPVVNFTLWKYYVLFRLSHFNMQKINGTEVTQNDMIMAERLFGILAHVASSELPQYRLISILGDARKKQFRYLLETKGKKPGIVSEENNDSKRLVGENTNRATLNYTTRDFYTEKLEEIKEKKKFCKMYIEDLVKEATEINMKNEALQKLWPQMFIELVRDAVIEIRNKNSYMKLCLQQITDQK", "length": 751 }, "evidence": [ { "id": "A0A8V0ZRF5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7FG58-1", "protein_name": "Leucine-rich repeat-containing protein 49", "gene_name": "Lrrc49", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIPGKYRSVSGRAANNVNCGLHLVIQTSSLSDKNKVEFKLNRETPSFPGRLLQHDLERNYSSRQGDGRVISPSPRNKSSCISSTTNVTELCGLDMRTATTSLSAFGDSSIQTPSKPRIRQGCHSAGPNVSGDHINLVSSSMPSFPILQRSSEEKTLYSDRLTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERRVASVVAKKEEEKKRESHKQSLLKEKKRLTINNVARKWDLQQRVANIAIIQDRKDSESPPQESCQIDGGTISAFPEEAGSLDAGLSSALQGLSVTETHLVELDGETLSLYGSGALECLDRNWSVQTAGMVTTVSFTFIEFDEIVQVLPKLKMKFPNSLHLKFRETNLVMLQQFNALAQLRRVDQLTIDPQGNPVVNFTLWKYYVLFRLSHFSMQKINGTEVTQNDMIMAERLFGILAHVASSELPQYRMISILGDARKKQFRYLLENKCKKPGILCEETSDSKRLMGENTNRATLNYTTREFYHEKLEEIKDKKKFCRLYVEDLVKEATAINMKNEALQKLWPQMFIELVRDAVIEIRSKDSYMKLCLQQITDQK", "length": 752 }, "evidence": [ { "id": "A0A8V0ZRF5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IUZ0-1", "protein_name": "Leucine-rich repeat-containing protein 49", "gene_name": "LRRC49", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIPGKYRSVSGRAANNVNCGLHLVIQTSSLPEKNKVEFKLNKDTSSFPGRLLQHDLERNYSSRQGDHINLVSSSLSSFPILQRSSEEKILYSDRLSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGLSTLRCLRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQQQRVANIATNEDRKDSDSPQDPCQIDGSTLSAFPEETGPLDSGLNNALQGLSVIDTYLVEVDGDTLSLYGSGALESLDRNWSVQTAGMITTVSFTFIEFDEIVQVLPKLKIKFPNSLHLKFKETNLVMLQQFNALAQLRRIDQLTIDPQGNPVVNFTLWKYYVLFRLSHFSMQKINGTEVTQNDMIMAERLFGILAHVASSELPQYRLISILGDARKKQFRYLLESKGKKPGIINEENNDSKRLVGENTNRATLNYTTRDFYNEKLEEIKEKKKFCKTYIEDLVKEATEINMKNEALQKLWPQMFIELVRDAVIEIRNKNSYMKLCLQQITDQK", "length": 686 }, "evidence": [ { "id": "A0A8V0ZRF5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91YK0-1", "protein_name": "Leucine-rich repeat-containing protein 49", "gene_name": "Lrrc49", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPGKYRSVSGRAANNVNCGLHLVIQTSSLSDKNKVEFRLNRETPPFPGRLLQHDLERNYSSRQGDHISLVSSSMPAFPILQRSSEEKTLYSDRLTLERQKLTVCPIIDGEEHLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGLDSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERRVASVVPKKEEEKKRESHKQSLLKEKKRLTINNVARKWDLQQRVANIASTQDRKDSESPPQESCQLDGGNISAFPEEAGSLDAGLSSALQGLSVTETHLVEIDGETLSLYGSGALECLDRNWSVQTAGMVTTVSFTFIEFDEIVQVLPKLKMKFPNSLHLKFRETNLVMLQQFNALAQLRRVDQLTIDPQGNPVVNFTLWKYYVLFRLSHFSMQKINGTEVTQNDMIMAERLFGILAHVASSELPQYRMISILGDARKKQFRYLLESKGKKPGIICEETSDSKRFLGENTNRATLNYTTREFYHEKLEEIKDKKKFCRLYVEDLVKEATAINMKNEALQKLWPQMFIELVRDAVIEIRSKDSYMKLCLQQITDQK", "length": 686 }, "evidence": [ { "id": "A0A8V0ZRF5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRF5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRF6-1", "uniprot_ac": "A0A8V0ZRF6", "uniprot_id": "A0A8V0ZRF6_CHICK", "mass": { "chemical_mass": 34493.0, "monoisotopic_mass": 34493.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Reverse transcriptase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF6", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZRF6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRF6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR33332", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33332", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZRF6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGVPQGSVLGPVLFNIFTDDLDEGIECTLSKFADDTKLAGSVDPPEVREALQRDLDRLDRWAEANGMGFNKTKCRVLHFGHNNPRQRYRLGAEWLEYCVEEMDLRVLIDTRLNMSQQCAQVAKKANGILACIRNSDSVVSRNGEVIVPLYSALVRLHLEYCVQFWAPHCKKDIEALERVQRRATKLVRGLEHRPYEEQLKELGLFSLEKRRLRGDLIALSNYLKGGCSELGVGLFSCVTSDRTRGNGFKLCQGRFRLDVRKYYFSERVVRHWNGLPRELVESLSLVVFKERLDVVLRDMV", "length": 301, "header": "tr|A0A8V0ZRF6-1|A0A8V0ZRF6_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZRF6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF6/entry#A0A8V0ZRF6-1", "sequence": { "sequence": "MSGVPQGSVLGPVLFNIFTDDLDEGIECTLSKFADDTKLAGSVDPPEVREALQRDLDRLDRWAEANGMGFNKTKCRVLHFGHNNPRQRYRLGAEWLEYCVEEMDLRVLIDTRLNMSQQCAQVAKKANGILACIRNSDSVVSRNGEVIVPLYSALVRLHLEYCVQFWAPHCKKDIEALERVQRRATKLVRGLEHRPYEEQLKELGLFSLEKRRLRGDLIALSNYLKGGCSELGVGLFSCVTSDRTRGNGFKLCQGRFRLDVRKYYFSERVVRHWNGLPRELVESLSLVVFKERLDVVLRDMV", "length": 301, "header": "tr|A0A8V0ZRF6-1|A0A8V0ZRF6_CHICK Isoform 1 of Reverse transcriptase domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZRF6-1" }, "locus": { "chromosome": "8", "start_pos": 17822037, "end_pos": 17821135, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059081.1", "url": "https://www.ensembl.org/id/ENSGALT00010059081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036045.1", "url": "https://www.ensembl.org/id/ENSGALP00010036045.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRF6" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 100, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRG2-1", "uniprot_ac": "A0A8V0ZRG2", "uniprot_id": "A0A8V0ZRG2_CHICK", "mass": { "chemical_mass": 31913.0, "monoisotopic_mass": 31913.0 }, "refseq": { "ac": "XP_025011498", "name": "protein CUSTOS isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011498" }, "gene_names": [ { "name": "C12orf43", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG2" } ] }, { "name": "C12orf43", "type": "synonym", "evidence": [ { "id": "XP_025011498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011498" } ] } ], "protein_names": [ { "name": "Protein CUSTOS", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG2/entry#names_and_taxonomy" } ] }, { "name": "protein CUSTOS isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025011498", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011498" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052546.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025011498.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025011498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011498" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "C12orf43", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG2", "locus": { "chromosome": "15", "start_pos": 9110968, "end_pos": 9105242, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022718", "url": "https://www.ensembl.org/id/ENSGALG00010022718" } ] } } ], "crossref": [ { "id": "A0A8V0ZRG2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRG2", "database": "AlphaFoldDB", "categories": [] }, { "id": "416966", "url": "https://www.ncbi.nlm.nih.gov/gene/416966", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WDCTALA", "url": "https://omabrowser.org/oma/group/WDCTALA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRG2", "url": "https://www.orthodb.org/?gene=A0A8V0ZRG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14482", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14482", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14482:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14482:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025011498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011498", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPCGRRRDYSARHAPRRRGFKMAARRDSCGTDSSSDSESSGGAAARFREAAWDCAKQAAVRTEPRGGGFTKDQRQAARPSLRREVNDHDEDGNELQTTPEFRAHVAKKLGAMLDSFITVLKDSSGPSPACVQQSDCGDDGFRLFSSSVPGDCGQSEQSPAPRRRRPPSSSDSDSDQEWQKYQEAAVSAADILKQSAFPELSQDSSQNMCQGYVEHRQKKKKKKKIKGENKTEEKIIDPAERDQVSKDLPWLVSANGQHKREDSNHTDNTVSPGAVMKKKKKKKKERE", "length": 287, "header": "tr|A0A8V0ZRG2-1|A0A8V0ZRG2_CHICK Isoform 1 of Protein CUSTOS OS=Gallus gallus OX=9031 GN=C12orf43 PE=3 SV=1 CANONICAL=A0A8V0ZRG2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG2/entry#A0A8V0ZRG2-1", "sequence": { "sequence": "MPCGRRRDYSARHAPRRRGFKMAARRDSCGTDSSSDSESSGGAAARFREAAWDCAKQAAVRTEPRGGGFTKDQRQAARPSLRREVNDHDEDGNELQTTPEFRAHVAKKLGAMLDSFITVLKDSSGPSPACVQQSDCGDDGFRLFSSSVPGDCGQSEQSPAPRRRRPPSSSDSDSDQEWQKYQEAAVSAADILKQSAFPELSQDSSQNMCQGYVEHRQKKKKKKKIKGENKTEEKIIDPAERDQVSKDLPWLVSANGQHKREDSNHTDNTVSPGAVMKKKKKKKKERE", "length": 287, "header": "tr|A0A8V0ZRG2-1|A0A8V0ZRG2_CHICK Isoform 1 of Protein CUSTOS OS=Gallus gallus OX=9031 GN=C12orf43 PE=3 SV=1 CANONICAL=A0A8V0ZRG2-1" }, "locus": { "chromosome": "15", "start_pos": 9108526, "end_pos": 9105441, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055233.1", "url": "https://www.ensembl.org/id/ENSGALT00010055233.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033417.1", "url": "https://www.ensembl.org/id/ENSGALP00010033417.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], 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"MSDLESSSSSSSDEEELERCREAALPAWGLEQRPRGPEKPGVDATNAKLPANQPSLRHKVDEHEQDGNELQTTPEFRAHVAKKLGALLDRSSLLCSGSLVVASGGSSLLSSITISEIVKEPRKSEVQQGALEDDGFRLFFTSIPGGPEKEAAPQPCRKRLPSSSSSDDGDEELRRCREAAVSASDILQESAIHGHVSVEKKKKRKLKKKAKKEDSADVAAAATSKAAVGRQEKESAQLNGDQAPPGTKKKKRKKKTKKASEASPSPPTKSAAAVPSN", "length": 277 }, "evidence": [ { "id": "A0A8V0ZRG2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRG2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RJG8-1", "protein_name": "Protein CUSTOS", "gene_name": "C12orf43", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSYLESSSSSSSDAEELERCREAAMPAWGLEQRPRGLEKPKAGAANTQLPTTQPSLRHKVDEHEQDGNELQTTPEFRAHVAKKLGALLDSSITISEVVKEPRKAEVRRGTPEDDGFRLFFTSIPGASEKEAAPQPRRKRLPSSSSSEDGDEELQRCREAAVSASDILQESAIHGPVSVEEKAKKKKRKLKKKAKKEASASVAAAATVTTTGKAAVGKQSKESAELNGAQVPLGTKKKKRKKKAKRAGEAAPSPPAKSAAATPVHRVLPVGTGPN", "length": 274 }, "evidence": [ { "id": "A0A8V0ZRG2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRG2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3UY34-1", "protein_name": "Protein CUSTOS", "gene_name": "Custos", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVAPSGAMSDSENSSSSSSDAEELARCREAATPAWGLEQRPGAAERPEAGAADKQAPTPQPSRRHEVNQHEEDGNDLRTTPEFRAHVAKKLGALLDSSIAIAEVWKKSQKAKMQQVAKEEDGFRLFFTSIPGGHKKEASPRPCRKRQPPSSSEDSDEELQRCREAAVSASDILQESAIHCPAKAEEKKKLKKKAKKKVDNADLAAAPGLEQVKEAGVVNGDPVSLGIQKKRKKKAKKSREAPLCPPAECAAAKPEN", "length": 256 }, "evidence": [ { "id": "A0A8V0ZRG2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRG2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5I034-1", "protein_name": "Protein CUSTOS", "gene_name": "Custos", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVAPSGAMSDSESSSSDSSDAEELARCREAATPAWGLEQRPREAERPAAGTADTQAPAPQPSRRREVNQHDEDGNELQTTPEFRAYVAKKLGALLDSSIAIAEVWKKTQQARLQQEAKEQQEAKEQQAAKEEQAAKKEEDGFRLFFTSVPGGHEKEASPRPCRKRQPPSSSEDSDEELQRCREAAVSASDILQESAIHCPAKVEKEAEKKKLKKKAKKKADADLAAATGLEQVKEAGSVNGDPVLSGTKKKKKKKAKKAREASLCPPAECAAAEPKN", "length": 277 }, "evidence": [ { "id": "A0A8V0ZRG2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRG2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96C57-1", "protein_name": "Protein CUSTOS", "gene_name": "CUSTOS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPSGTVSDSESSNSSSDAEELERCREAAMPAWGLEQRPHVAGKPRAGAANSQLSTSQPSLRHKVNEHEQDGNELQTTPEFRAHVAKKLGALLDSFITISEAAKEPAKAKVQKVALEDDGFRLFFTSVPGGREKEESPQPRRKRQPSSSSEDSDEEWRRCREAAVSASDILQESAIHSPGTVEKEAKKKRKLKKKAKKVASVDSAVAATTPTSMATVQKQKSGELNGDQVSLGTKKKKKAKKASETSPFPPAKSATAIPAN", "length": 262 }, "evidence": [ { "id": "A0A8V0ZRG2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRG2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG2" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG2" } ], "pmid": "" }, { "name": "negative regulation of Wnt signaling 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"tr|A0A8V0ZRG9-1|A0A8V0ZRG9_CHICK Isoform 1 of G protein-coupled receptor 155 OS=Gallus gallus OX=9031 GN=GPR155 PE=4 SV=1 CANONICAL=A0A8V0ZRG9-1" }, "locus": { "chromosome": "7", "start_pos": 16525689, "end_pos": 16505349, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054883.1", "url": "https://www.ensembl.org/id/ENSGALT00010054883.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033181.1", "url": "https://www.ensembl.org/id/ENSGALP00010033181.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of TORC1 signaling", "id": "GO:1904263", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904263", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG9" } ], "pmid": "" }, { 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}, { "name": "cellular response to amino acid starvation", "id": "GO:0034198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034198", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRG9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": 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virus subgroup C receptor-related protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419425" }, "gene_names": [ { "name": "TATDN3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ] }, { "name": "TATDN3", "type": "synonym", "evidence": [ { "id": "XP_419425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419425" } ] } ], "protein_names": [ { "name": "Choline/ethanolamine transporter FLVCR1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2/entry#names_and_taxonomy" } ] }, { "name": "Heme transporter FLVCR1", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2/entry#names_and_taxonomy" } ] }, { "name": "feline leukemia virus subgroup C receptor-related protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_419425", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419425" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_419425.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_419425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419425" } ] }, { "annotation": "Uniporter that mediates the transport of extracellular choline and ethanolamine into cells, thereby playing a key role in phospholipid biosynthesis. Choline and ethanolamine are the precursors of phosphatidylcholine and phosphatidylethanolamine, respectively, the two most abundant phospholipids. Transport is not coupled with proton transport and is exclusively driven by the choline (or ethanolamine) gradient across the plasma membrane. Also acts as a heme b transporter that mediates heme efflux from the cytoplasm to the extracellular compartment.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2#function" }, { "database": "UniProtKB", "id": "ARBA00060240", "url": "https://www.uniprot.org/uniprotkb/ARBA00060240#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TATDN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2", "locus": { "chromosome": "3", "start_pos": 21476289, "end_pos": 21491389, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019252", "url": "https://www.ensembl.org/id/ENSGALG00010019252" } ] } } ], "crossref": [ { "id": "A0A8V0ZRH2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17455", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17455", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421366", "url": "https://www.ncbi.nlm.nih.gov/gene/421366", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421365", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421365", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LDLMGHN", "url": "https://omabrowser.org/oma/group/LDLMGHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRH2", "url": "https://www.orthodb.org/?gene=A0A8V0ZRH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10924", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10924", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10924:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10924:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-189451", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189451", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-917937", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-917937", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_419425", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_419425", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "32747", "url": "https://www.rhea-db.org/rhea/32747", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "32751", "url": "https://www.rhea-db.org/rhea/32751", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "75443", "url": "https://www.rhea-db.org/rhea/75443", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEDGSEEEEGEAEGERGEMLGAPQHNGFLPGKEAENGGPGGCTAGGGRVETRLSRRRLAVLAVFSCYSLVNAFQWIQYSILSNVFVHFYSVSFTEIDWLSMVYMVAYVPLILPATWLLDARGLRLTALLGAGLNALGAWLKCASLAPGRYALTMAAQAVCAVAQVFILGLPSRIASVWFGPAEVSTACSVAVLGNQLGTAIGFLLPPVLVPNTPDDIDLMAHNISIMFYGTAIVSTLLFFLTGVVFEEKPKYPPSHSQALLQAMPPEDYSYKQSIINLVKNVPFVLLLISYGIMTGTFYSVSTLLNQMIVTHYEGEEVNAGRIGLTLVVAGMVGSIICGLWLDYTKTYKQTTLIVYILSFIGMVVFTFTLDLGYLIVVFVTGGVLGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNASAQIFGIVFTLVQGKLTTDYSPRAGNLFLCAWLFVGIILTALIKSDLRRHNVNSGIVNMDVKAVPVDNPVERETCTALKIQSDL", "length": 503, "header": "tr|A0A8V0ZRH2-1|A0A8V0ZRH2_CHICK Isoform 1 of Choline/ethanolamine transporter FLVCR1 OS=Gallus gallus OX=9031 GN=TATDN3 PE=3 SV=1 CANONICAL=A0A8V0ZRH2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2/entry#A0A8V0ZRH2-1", "sequence": { "sequence": "MVEDGSEEEEGEAEGERGEMLGAPQHNGFLPGKEAENGGPGGCTAGGGRVETRLSRRRLAVLAVFSCYSLVNAFQWIQYSILSNVFVHFYSVSFTEIDWLSMVYMVAYVPLILPATWLLDARGLRLTALLGAGLNALGAWLKCASLAPGRYALTMAAQAVCAVAQVFILGLPSRIASVWFGPAEVSTACSVAVLGNQLGTAIGFLLPPVLVPNTPDDIDLMAHNISIMFYGTAIVSTLLFFLTGVVFEEKPKYPPSHSQALLQAMPPEDYSYKQSIINLVKNVPFVLLLISYGIMTGTFYSVSTLLNQMIVTHYEGEEVNAGRIGLTLVVAGMVGSIICGLWLDYTKTYKQTTLIVYILSFIGMVVFTFTLDLGYLIVVFVTGGVLGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNASAQIFGIVFTLVQGKLTTDYSPRAGNLFLCAWLFVGIILTALIKSDLRRHNVNSGIVNMDVKAVPVDNPVERETCTALKIQSDL", "length": 503, "header": "tr|A0A8V0ZRH2-1|A0A8V0ZRH2_CHICK Isoform 1 of Choline/ethanolamine transporter FLVCR1 OS=Gallus gallus OX=9031 GN=TATDN3 PE=3 SV=1 CANONICAL=A0A8V0ZRH2-1" }, "locus": { "chromosome": "3", "start_pos": 21472812, "end_pos": 21464921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052465.1", "url": "https://www.ensembl.org/id/ENSGALT00010052465.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031372.1", "url": "https://www.ensembl.org/id/ENSGALP00010031372.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421365", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421365", "resource": "KEGG Pathway" }, { "id": "R-GGA-189451", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189451", "resource": "Reactome", "description": "Heme biosynthesis" }, { "id": "R-GGA-917937", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-917937", "resource": "Reactome", "description": "Iron uptake and transport" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RXV4-1", "protein_name": "Choline/ethanolamine transporter FLVCR1", "gene_name": "Flvcr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARPDDEVGPAVAPGHPLGKGYLPVPKGAPDGEARLVPQNGPEALNGGPGLGPLIAGAQGGPQALIAAEEETQARLLPAGDGEDVPCPACPPRTALSPRRFVVLLIFSLYSLVNAFQWIQYSSISNVFEDFYEVSPLHINWLSMVYMVAYVPLIFPATWLLDTRGLRLTALLGSGLNCLGAWVKCGSVQRHLFWVTMLGQILCSVAQVFILGLPSPVASVWFGPKEVSTACATAVLGNQLGTAVGFLLPPVLVPALGTQNSTGLLAHTQNNTDLLAHNINTMFYGTAFISTFLFFLTIIAFKEKPPLPPSQAQAVLRDSPPEEYSYKSSIWNLCRNIPFVLLLVSYGIMTGAFYSISTLLNQIILTYYVGEEVNAGRIGLTLVVAGMVGSILCGLWLDYTKTYKQTTLIVYVLSFIGMLIFTFTLNLGYIIVVFFTGGILGFFMTGYLPLGFEFAVEITYPESEGMSSGLLNTAAQILGIFFTLAQGKITTDYNSPEAGNIFLCAWMFVGIILTALIKSDLRRHNINTGLTNIDVKAVPVDSRVDPKPKVMVSIQSESSL", "length": 560 }, "evidence": [ { "id": "A0A8V0ZRH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRH2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B7A6-1", "protein_name": "Choline/ethanolamine transporter FLVCR1", "gene_name": "FLVCR1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARPDDEEGTAMASGHPPANGYLPVPGDAPAGKVSAETQNGPTAGCLALNGVSRDSTKATASGTPDGPKTPLAPEEETQARLLPKDPGEETPGGEGTLVPRIALSPRRFVVLLIFSAYSLVNAFQWIQYSIISNVFEGFYNVSSLHIDWLSMVYMLAYVPLIFPATWLLDTRGLRLTALLGSGLNCLGAWIKCGSVKQHLFWVTMLGQCLCSVAQVFILGLPSHIASVWFGPKEVSTACATAVLGNQLGTAVGFLLPPVLVPNTQNNTQLLARNISTMFYGTSAVATLLFILTVIAFKEKPQYPPSQAQAVLQDSPPGEYSYVKSIRNLFKNIPFVLLLISYGIMTGAFYSVSTLLNQMILTHYEGEEVNAGRIGLTLVVAGMVGSILCGLWLDYTKTYKHTTLTVYILSFVGMVIFTFTLNLGHIIIVFVTGGLLGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNAAAQIFGILFTLAQGKLTSAYGPRTGNVFLCVWIFGGIILTALIKSDLKRHNINKGITNGDIKAVPVDSPTDQESKTVLMSKQSESAI", "length": 556 }, "evidence": [ { "id": "A0A8V0ZRH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRH2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S2X6-1", "protein_name": "Choline/ethanolamine transporter FLVCR1", "gene_name": "FLVCR1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPDDEEEAAVANGHPPSNGYLPVPGDAPAGEMSAETQNEPKTGCLALNGVSRDSPKAVSRALDRPKTPLAPEEETQAWLLPKGPSEENPGAENTLVPRTALSPRRFVILLVFSLYSLVNAFQWIQYSIISNVFEGFYNVPSLHIDWLSMVYMLAYVPLIFPATWLLDTRGLRLTALLGAGLNALGAWIKCGSVQQHLFWVTMMGQCLCSVAQVFILGLPSHIASVWFGPKEVSTACATAVLGNQLGTAVGFLLPPVLVPNTQNNTELLACNISTMFYGTAAVATFLFILTVIAFKEKPQYPPSQAQAVLQDNPPEDYSYVKSIRNLFRNIPFVLLLITYGIMTGAFYSVSTLLNQMILTYYEGEEVNAGRIGLTLVLAGMVGSILCGLWLDYTKTYKHTTLTVYILSFVGMVVFTFTLNLGHIIILFVTGGLLGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNAAAQIFGILFTLAQGKLISNYGPEIGNIFLCVWMFIGIILTALIKSDLKRHNINKGVANGDMKAVPVDSPTDQESKTILMSKQSESATDSEV", "length": 559 }, "evidence": [ { "id": "A0A8V0ZRH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRH2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0RB11-1", "protein_name": "Choline/ethanolamine transporter FLVCR1", "gene_name": "Flvcr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARPDDEVGPAVAPGHPLEKGYLPVPRGAPDGEACVEPHDGPEALNGGPGLGRLVGGAPEGPQTLLAAEEETQARLLPAGGGEDVPCPARPPRTALSPRRFVVLLIFSLYSLVNAFQWIQYSSISNVFEDFYQVSPLHINWLSMVYMVAYVPLIFPATWLLDTRGLRLTALLGSGLNCLGAWVKCGSVKQHLFWVTMLGQILCSVAQVFILGLPSPVASVWFGPKEVSTACATAVLGNQLGTAVGFLLPPVLVPKTQNNNTGLLADTQNSTDLLDDTQNSTDLLADNISIMFYGTAFVSTFLFFLTVIAFKERPLLPPSQAQAVLRDSPPAEYSYKTSICNLFRNVPFVLLLISYGIMTGAFYSVSTLLNQIILTHYEGEEVNAGRIGLTLVVAGMVGSILCGLWLDYTKTYKQTTLIVYILSFVGMVIFTFTLKLGYIIVVFFTGGILGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNTAAQIFGILFTLAQGKLTTDYNPEAGNIFLCAWMFVGIILTALIKSDLRRHNINTGLTNSDVKAVPVDSLIDQKPKAMVSVQLESSL", "length": 568 }, "evidence": [ { "id": "A0A8V0ZRH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRH2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5RGT2-1", "protein_name": "Choline/ethanolamine transporter FLVCR1", "gene_name": "flvcr1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVAGEFLQEQHVLPDSAPEGNTDEDSGYKELSNGSVHITLDPKVLEQELPPPDEKEAMLPAEQRSDALETRLYWRRFAVLAVFSLYSLVNAFQWIQYSIITNIFMDYYGVTSIAIDWLSVVYMVAYVPLIFPATWLLDKKGLRVTALLGAGLNALGAWVKCASVGPGLFWVTMTAQIICSVAQVFILGLPSRIASVWFGPREVSTACAFAVLGNQLGVAIGFLLPPVLVPNTADDKDLMGHNISIMFYGTAAVSTLLFLLTIFVIKDRPPLPPSKAQAVLSTGPAEDYSYKKSIINLFRNKPFILLLISYGIMTGSFYSVSTLLNQMIITHYKGEELNTGRIGLTLVVAGMFGSILCGIWLDRTKTYKLTTLIVYVLSFIGMVVFTFTLNVHLLVIFFTAGVLGFFMTGYLPIGFEFGVEITYPESEGTSSGLLNAFAQVFGIIFTLIQGKLTTDYNPLSGNIFLCAWILLGIVLTALIKSDLKRHDVNVGNINKAQAVSVPTELPSDKASSDVKMESSGLPHETTI", "length": 527 }, "evidence": [ { "id": "A0A8V0ZRH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRH2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9Y5Y0-1", "protein_name": "Choline/ethanolamine transporter FLVCR1", "gene_name": "FLVCR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARPDDEEGAAVAPGHPLAKGYLPLPRGAPVGKESVELQNGPKAGTFPVNGAPRDSLAAASGVLGGPQTPLAPEEETQARLLPAGAGAETPGAESSPLPLTALSPRRFVVLLIFSLYSLVNAFQWIQYSIISNVFEGFYGVTLLHIDWLSMVYMLAYVPLIFPATWLLDTRGLRLTALLGSGLNCLGAWIKCGSVQQHLFWVTMLGQCLCSVAQVFILGLPSRIASVWFGPKEVSTACATAVLGNQLGTAVGFLLPPVLVPNTQNDTNLLACNISTMFYGTSAVATLLFILTAIAFKEKPRYPPSQAQAALQDSPPEEYSYKKSIRNLFKNIPFVLLLITYGIMTGAFYSVSTLLNQMILTYYEGEEVNAGRIGLTLVVAGMVGSILCGLWLDYTKTYKQTTLIVYILSFIGMVIFTFTLDLRYIIIVFVTGGVLGFFMTGYLPLGFEFAVEITYPESEGTSSGLLNASAQIFGILFTLAQGKLTSDYGPKAGNIFLCVWMFIGIILTALIKSDLRRHNINIGITNVDVKAIPADSPTDQEPKTVMLSKQSESAI", "length": 555 }, "evidence": [ { "id": "A0A8V0ZRH2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRH2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "erythrocyte maturation", "id": "GO:0043249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" }, { "name": "mitochondrial transport", "id": "GO:0006839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" }, { "name": "erythrocyte differentiation", "id": "GO:0030218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030218", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" }, { "name": "heme biosynthetic process", "id": "GO:0006783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" }, { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" }, { "name": "heme export", "id": "GO:0097037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" }, { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "heme transmembrane transporter activity", "id": "GO:0015232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015232", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" }, { "name": "choline transmembrane transporter activity", "id": "GO:0015220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015220", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" }, { "name": "ethanolamine transmembrane transporter activity", "id": "GO:0034228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "32747", "name": "", "equation": "ethanolamine(in) = ethanolamine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32747", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32747" } ] }, { "id": "32751", "name": "", "equation": "choline(out) = choline(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "32751", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/32751" } ] }, { "id": "75443", "name": "", "equation": "heme b(in) = heme b(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "75443", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/75443" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRH2" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 61, "end_pos": 467, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 }, { "start_pos": 418, "end_pos": 420 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRI2-1", "uniprot_ac": "A0A8V0ZRI2", "uniprot_id": "A0A8V0ZRI2_CHICK", "mass": { "chemical_mass": 50747.0, "monoisotopic_mass": 50747.0 }, "refseq": {}, "gene_names": [ { "name": "ACRBP", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2" } ] } ], "protein_names": [ { "name": "Acrosin-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2/entry#names_and_taxonomy" } ] }, { "name": "Acrosin-binding protein, 60 kDa form", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2/entry#names_and_taxonomy" } ] }, { "name": "Proacrosin-binding protein sp32", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Acrosomal protein that maintains proacrosin (pro-ACR) as an enzymatically inactive zymogen in the acrosome. Involved also in the acrosome formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2#function" }, { "database": "UniProtKB", "id": "ARBA00045517", "url": "https://www.uniprot.org/uniprotkb/ARBA00045517#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ACRBP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2", "locus": { "chromosome": "1", "start_pos": 76989981, "end_pos": 77008309, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021614", "url": "https://www.ensembl.org/id/ENSGALG00010021614" } ] } } ], "crossref": [ { "id": "A0A8V0ZRI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR009865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRI2", "url": "https://www.orthodb.org/?gene=A0A8V0ZRI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21362", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21362", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21362:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21362:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07222", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07222", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZRI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLATSAAPPVPPVGSPLSDGEYQLFFSSLWPIWKAHASCHLRQTFGCLSPAVLRLDEQENHGRVPEGPVCSAFPEAPWFQTFCQFAQYRCSKRKFYVKVSSGTGAMKEKEGEGRGGEGRGGEGRGGEGRGGEGRGGEGRGGEGRGGEGRGGKGREGKGREGKGREGKGREGKGREGKGREGKGREGKGREGKGREKSSYFSLFHSANPMSEFFSKRPSSSRGRDLTSFIHFSASLLALTRKEAVMILCYAVLEGVCVSSVVTQAWKELEEKVLGFGDSVCDSLGRRHMNLCPACAFCSLKVEQCQNIYHLRRVHCKTGSFITYINPQISTQHRAAGNKVLKPSKYFGTQVYRGLRPEYWCSLIATQGCDDPRVMLWLQAEYATFRAGDVPSKICDSSGVQHPTYCAFKSHQCLQHSLYNQRVIRHGCFTNQTYHVLSEEEGKEEVRRWHQRFLSLTEG", "length": 459, "header": "tr|A0A8V0ZRI2-1|A0A8V0ZRI2_CHICK Isoform 1 of Acrosin-binding protein OS=Gallus gallus OX=9031 GN=ACRBP PE=4 SV=1 CANONICAL=A0A8V0ZRI2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2/entry#A0A8V0ZRI2-1", "sequence": { "sequence": "MLLATSAAPPVPPVGSPLSDGEYQLFFSSLWPIWKAHASCHLRQTFGCLSPAVLRLDEQENHGRVPEGPVCSAFPEAPWFQTFCQFAQYRCSKRKFYVKVSSGTGAMKEKEGEGRGGEGRGGEGRGGEGRGGEGRGGEGRGGEGRGGEGRGGKGREGKGREGKGREGKGREGKGREGKGREGKGREGKGREGKGREKSSYFSLFHSANPMSEFFSKRPSSSRGRDLTSFIHFSASLLALTRKEAVMILCYAVLEGVCVSSVVTQAWKELEEKVLGFGDSVCDSLGRRHMNLCPACAFCSLKVEQCQNIYHLRRVHCKTGSFITYINPQISTQHRAAGNKVLKPSKYFGTQVYRGLRPEYWCSLIATQGCDDPRVMLWLQAEYATFRAGDVPSKICDSSGVQHPTYCAFKSHQCLQHSLYNQRVIRHGCFTNQTYHVLSEEEGKEEVRRWHQRFLSLTEG", "length": 459, "header": "tr|A0A8V0ZRI2-1|A0A8V0ZRI2_CHICK Isoform 1 of Acrosin-binding protein OS=Gallus gallus OX=9031 GN=ACRBP PE=4 SV=1 CANONICAL=A0A8V0ZRI2-1" }, "locus": { "chromosome": "1", "start_pos": 77008309, "end_pos": 76990398, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052477.1", "url": "https://www.ensembl.org/id/ENSGALT00010052477.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031384.1", "url": "https://www.ensembl.org/id/ENSGALP00010031384.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fertilization", "id": "GO:0009566", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009566", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2" } ], "pmid": "" }, { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 431, "end_pos": 433 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRJ5-1", "uniprot_ac": "A0A8V0ZRJ5", "uniprot_id": "A0A8V0ZRJ5_CHICK", "mass": { "chemical_mass": 46834.0, "monoisotopic_mass": 46834.0 }, "refseq": { "ac": "NP_001244270", "name": "secernin-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244270" }, "gene_names": [ { "name": "SCRN3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ5" } ] }, { "name": "SCRN3", "type": "synonym", "evidence": [ { "id": "NP_001244270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244270" } ] } ], "protein_names": [ { "name": "Secernin 3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ5/entry#names_and_taxonomy" } ] }, { "name": "secernin-3", "type": "synonym", "evidence": [ { "id": "NP_001244270", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244270" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267655.179561.1, SRR13267656.2482.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03376185, SAMN04013384 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1. On Sep 23, 2021 this sequence version replaced NP_001244270.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data from different strains because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001244270", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244270" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCRN3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ5", "locus": { "chromosome": "7", "start_pos": 16527051, "end_pos": 16537342, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022568", "url": "https://www.ensembl.org/id/ENSGALG00010022568" } ] } } ], "crossref": [ { "id": "A0A8V0ZRJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "426472", "url": "https://www.ncbi.nlm.nih.gov/gene/426472", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426472", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426472", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CYYDVSD", "url": "https://omabrowser.org/oma/group/CYYDVSD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRJ5", "url": "https://www.orthodb.org/?gene=A0A8V0ZRJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWH2", "url": "https://www.orthodb.org/?gene=A0A8V0ZWH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12994", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12994", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12994:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12994:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001244270", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001244270", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWH2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARPPPRSCDTFVALPPAAAGGRVVFGKNSDRPSDEVQEVLYVPAAAHPAGAQLECTYITVEQAEQTYAVVLSRPSWLWGAEMGANEHGVCIGNEAVWGREEVCDAEALLGMDLVRLGLERADTAEKALTVIVDLLEKYGQGGNCMESHMAFTYHNSFLIADRKEAWVLETSGKHWAAEKVEGGVRNISNQLSITTKIDREHPEMREYAKSKGWWDGEKEFDFAATYSYVNTARMTTSRSRYCEGYKLLNKHKGAITAETMMEILRDKESGINMEGGFMTTGSMVSVLPQDPNLPCIHFFTGTPDPARSVFKPFIFVPGITELLKTSSPTFGPDDPVKKQPRFQSKPDRRHELYKKHESAAVVMETMKGKGKKMLEEIQTLEKRKMSEMESILQNGCTDINQPVNLFSQCVDEELKIYG", "length": 420, "header": "tr|A0A8V0ZRJ5-1|A0A8V0ZRJ5_CHICK Isoform 1 of Secernin 3 OS=Gallus gallus OX=9031 GN=SCRN3 PE=1 SV=1 CANONICAL=A0A8V0ZRJ5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ5/entry#A0A8V0ZRJ5-1", "sequence": { "sequence": "MAARPPPRSCDTFVALPPAAAGGRVVFGKNSDRPSDEVQEVLYVPAAAHPAGAQLECTYITVEQAEQTYAVVLSRPSWLWGAEMGANEHGVCIGNEAVWGREEVCDAEALLGMDLVRLGLERADTAEKALTVIVDLLEKYGQGGNCMESHMAFTYHNSFLIADRKEAWVLETSGKHWAAEKVEGGVRNISNQLSITTKIDREHPEMREYAKSKGWWDGEKEFDFAATYSYVNTARMTTSRSRYCEGYKLLNKHKGAITAETMMEILRDKESGINMEGGFMTTGSMVSVLPQDPNLPCIHFFTGTPDPARSVFKPFIFVPGITELLKTSSPTFGPDDPVKKQPRFQSKPDRRHELYKKHESAAVVMETMKGKGKKMLEEIQTLEKRKMSEMESILQNGCTDINQPVNLFSQCVDEELKIYG", "length": 420, "header": "tr|A0A8V0ZRJ5-1|A0A8V0ZRJ5_CHICK Isoform 1 of Secernin 3 OS=Gallus gallus OX=9031 GN=SCRN3 PE=1 SV=1 CANONICAL=A0A8V0ZRJ5-1" }, "locus": { "chromosome": "7", "start_pos": 16537297, "end_pos": 16530941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054925.1", "url": "https://www.ensembl.org/id/ENSGALT00010054925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033207.1", "url": "https://www.ensembl.org/id/ENSGALP00010033207.1" } ] } }, { "isoform_ac": "A0A8V0ZWH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ5/entry#A0A8V0ZWH2-1", "sequence": { "sequence": "MAARPPPRSCDTFVALPPAAAGGRVVFGKNSDRPSDEVQEVLYVPAAAHPAGAQLECTYITVEQAEQTYAVVLSRPSWLWGAEMGANEHGVCIGNEAVWGREEVCDAEALLGMDLVRLGLERADTAEKALTVIVDLLEKYGQGGNCMESHMAFTYHNSFLIADRKEAWVLETSGKHWAAEKVEGGVRNISNQLSITTKIDREHPEMREYAKSKGWWDGEKEFDFAATYSYVNTARMTTSRSRYCEGYKLLNKHKGAITAETMMEILRDKESGINMEGGFMTTGSMVSVLPQDPNLPCIHFFTGTPDPARSVFKPFIFVPGITELLKTSSPTFGPDDPVKKQPRFQSKPDRRHELYKKHESAAVVMETMKGKGKKMLEEIQTLEKRKMSEMESILQNGCTDINQPVNLFSQNY", "length": 412, "header": "tr|A0A8V0ZWH2-1|A0A8V0ZRJ5_CHICK Computationally mapped isoform of Secernin 3 OS=Gallus gallus OX=9031 GN=SCRN3 PE=1 SV=1 CANONICAL=A0A8V0ZRJ5-1" }, "locus": { "chromosome": "7", "start_pos": 16537297, "end_pos": 16528055, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054930.1", "url": "https://www.ensembl.org/id/ENSGALT00010054930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033210.1", "url": "https://www.ensembl.org/id/ENSGALP00010033210.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426472", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K189-1", "protein_name": "Secernin 3", "gene_name": "Scrn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPYSCDTFVALPPATVGNRVIFGKNSDRLFDEVQEVIYFPAAVHSDLEKRLKCTYIEVDQVPETYAVVLSRPAWLWGAEMGANEHGVCIGNEAIWGREDISKEEALLGMDLVRLGLERADTAEKALNVIVDLLGKYGQGGNCAEGEEFSYYNSFLIADRNEAWILETSGKFWAAEKVQGVRNISNQFSITTKIDREHPDMRNYAKQRGWWDGKEEFDFAAAYSYTDTATMMTSPSRYCQGHKLLNKHKGNITYETMVEILRDRPSGINMKGEFLTTASMVSILPQDPSLPCIHLLTGTPHPERSVFKPFIFVPHVSPLLDTKSPTFELERPVAKKPYVKPDRRHLLYQNHQQALEMISNHKEKGKTILDNVRKLEKEVFEEIESILQNRHLDMDKTVNLFPQYVRDEIKIYQPNISS", "length": 418 }, "evidence": [ { "id": "A0A8V0ZRJ5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9T9V5-1", "protein_name": "Secernin 3", "gene_name": "SCRN3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLAKDFPILEAELEYATPRSESNVNKLCRLTGTAPPVAVGTSGVKGDDFRQLAPLHPFSLLSPFTWVARRPVKKKMEPCSCDTFVALPPATIDNRIIFGKNSDRPCDEVQEVVYFPAAVHDNLKEHLKGTWIQSLGPGRFHLLRASCTLVPQLLNTTAREATSTRSLHTTARVAPAGHNSRKRGCINKDPAQPKCTYIEIDQVPETYAVVLSRPAWLWGAEMGANEHGVCIGNEAVWGREKVCDEEALLGMDLVRLGLERGDTAEKALNVIVDLLEKYGQGGNCSEGRMVFSYHNSFLIADRNEAWILETAGKYWAAEKVEEGVRNISNQLSITTKIDREHPDMRNYAKQRGWWDGKKEFDFAATYSYLDTAKMMISPGRYCEGYKLLNKHKGNITFETMVEILRDKPSGINMEGEFLTTASMVSILPQDSKLPCIHFFTGTPDPERSVFKPFIFVPNISQLLNTSSPTFELEDSVGKKLQFNSKPDRRHPLYQKHQQALEILDNKTEKAKTMLDNMRKLEKELFKEMESVLQNKHLQVDKIVNLLHQCTEDEIRIYKSNVSS", "length": 564 }, "evidence": [ { "id": "A0A8V0ZRJ5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRJ5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3IJH6-1", "protein_name": "Secernin-3 isoform X1", "gene_name": "Scrn3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPYSCDTFVALPPATVGNRVIFGKNSDRLFDEVQEVIYFPAAVHNDLQKRLKCTYIEIDQVPETYAVVLSRPAWLWGAEMGANEHGVCIGNEAVWGREDISKEEALLGMDLVRLGLERADTAEKALDVIVDLLEKYGQGGNCAEGEEFSYYNSFLIADRNEAWILETSGKYWAAEKVQGVRNISNQLSITTKIDREHPNMRNYAKHKGWWDGKEDFDFTAAYSYMNTASMMTSSSRYCQGYKLLNKHKGNITFETMMEILRDEPSGINMKGEFLTTSSMVSILPRDSSLACIHFFTGTPHPERSVFKPFIFVPNISQLLDTKSPTFDLERPMAKKPYVKPDRRHPLYQKHQQAWEVISNSKEKSKTTLDDMRKLEKEVFEEMESILQNKHLDVDKTVNLFTQCVKDEIKIYQSNISS", "length": 418 }, "evidence": [ { "id": "A0A8V0ZRJ5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRJ5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3TMH2-1", "protein_name": "Secernin-3", "gene_name": "Scrn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPYSCDTFVALPPATVGNRVIFGKNSDRLFDEVQEVIYCPAAVHNDLEKRLKCTYIEVDQVPETYAVVLSRPAWLWGAEMGANEHGVCIGNEAVWGREDISKEEALLGMDLVRLGLERADTAEKALDVIVDLLEKYGQGGNCAEGKEFSYYNSFLIADRNEAWILETSGKYWAAERVQGVRNISNQLSITTKIDREHPDMRNYAKQRGWWDGKEEFDFTAAYSYIDTAAMMTSPSRYCQGYKLLDKHRGNITFETMMEILRDRPSGINMKGEFLTTASMVSVLPQDPSLPCIHLFTATPHPERSVFKPFIFVPHISPLLDTKSPTFEPERPVAKKPYVKPDRRHPLYQKHQEALEMISNSKEKGKTILDKMRKLEKAVSEEIESILQSGHLDEEKTVNLFPQYVKDEIKIYQSNISS", "length": 418 }, "evidence": [ { "id": "A0A8V0ZRJ5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VI64-1", "protein_name": "Secernin-3", "gene_name": "Dmel\\CG10098", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTNGDCFVVLPENCAEGTLIIGRNAEDEKNVNVASEVCFYDATEVLEGKTDGGASAETGGDMLRVILQKPQPGLWGGDFGANERGVALGLTWAAGENEAKDSDSLLGTDIVRLTLAVAKDVDDAVDRIGALVASHGHDNSKLNFIACDAAAAWLVSCSGKVWAAEKLEASFLRLPSGGLAVTTVVNKSSEGLDDAASFAAAHDAEAQAPAVDWCGPKPAGDGTYTQHDMFETLRSASNASSSRAATVSVLSVKGISCHWFTGTPNAAESVFKPFVFAPNPRISPLTQVQAEADLTLLHKLHSQRKPAALEHLRSLELSCVDELNNYFSLQDHASDELDELLKDCVEAEVKFYR", "length": 353 }, "evidence": [ { "id": "A0A8V0ZRJ5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRJ5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ5" } ], "pmid": "" }, { "name": "detection of temperature stimulus involved in sensory perception of pain", "id": "GO:0050965", "url": 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"biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRJ7-1", "uniprot_ac": "A0A8V0ZRJ7", "uniprot_id": "A0A8V0ZRJ7_CHICK", "mass": { "chemical_mass": 193948.0, "monoisotopic_mass": 193948.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Mucin 6, oligomeric mucus/gel-forming", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Ovomucin, the glycoprotein responsible for the gel properties of egg white, is composed for 2 subunits, alpha-ovomucin/MUC5B and beta-ovomucin/MUC6.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7#function" }, { "database": "UniProtKB", "id": "ARBA00054401", "url": "https://www.uniprot.org/uniprotkb/ARBA00054401#function" }, { "database": "UniProtKB", "id": "A0A8V0ZWS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWS2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7", "locus": {} } ], "crossref": [ { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339:SF264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339:SF264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-913709", "url": 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"length": 1764, "header": "tr|A0A8V0ZRJ7-1|A0A8V0ZRJ7_CHICK Isoform 1 of Mucin 6, oligomeric mucus/gel-forming OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZRJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7/entry#A0A8V0ZRJ7-1", "sequence": { "sequence": "MQGCFSKLKGRKGALLLTVNKRVLLLLQLLFDFLSRILSKDSCSTWGGGHFSTFDKYQYDFTGTCNYIFATVCDESSPDFNIQFRRGLDKKIARIIIELGPSVIIVEKDSISVRSVGVIKLPYASNGIQIAPYGRSVRLVAKLMEMELVVMWNNEDYLMVNLWMFSWILCFPEAIPAVLTEKKYMGKTCGMCGNYDGYELNDFVSEGKLLDTYKFAALQKMDDPSEICLSEEISIPAIPHKKYAVICSQLLNLVSPTCSVPKDGFVTRCQLDMQDCSEPGQKNCTCSTLSEYSRQCAMSHQVVFNWRTENFCSVGKCSANQIYEECGSPCIKTCSNPEYSCSSHCTYGCFCPEGTVLDDISKNRTCVHLEQCPCTLNGETYAPGDTMKAACRTCKCTMGQWNCKELPCPGRCSLEGGSFVTTFDSRSYRFHGVCTYILMKSSSLPHNGTLMAIYEKSGYSHSETSLSAIIYLSTKDKIVISQNELLTDDDELKRLPYKSGDITIFKQSSMFIQMHTEFGLELVVQTSPVFQAYVKVSAQFQGRTLGLCGNYNGDTTDDFMTSMDITEGTASLFVDSWRAGNCLPAMERETDPCALSQLNKISAETHCSILTKKGTVFETCHAVVNPTPFYKRCVYQACNYEETFPYICSALGSYARTCSSMGLILENWRNSMDNCTITCTGNQTFSYNTQACERTCLSLSNPTLECHPTDIPIEGCNCPKGMYLNHKNECVRKSHCPCYLEDRKYILPDQSTMTGGITCYCVNGRLSCTESCKAPKKYISCSDSLENKYGATCAPTCQMLATGIECIPTKCESGCVCADGLYENLDGRCVPPEECPCEYGGLSYGKGEQIQTECEICTCRKGKWKCVQKSRCSSTCNLYGEGHITTFDGQRFVFDGNCEYILAMDGCNVNRPLSSFKIVTENVICGKSGVTCSRSISIYLGNLTIILRDETYSISGKNLQVKYNVKKNALHLMFDIIIPGKYNMTLIWNKHMNFFIKISRETQETICGLCGNYNGNMKDDFETRSKYVASNELEFVNSWKENPLCGDVYFVVDPCSKNPYRKAWAEKTCSIINSQVFSACHNKVNRMPYYEACVRDSCGCDIGGDCECMCDAIAVYAMACLDKGICIDWRTPEFCPVYCEYYNSHRKTGSGGAYSYGSSVNCTWHYRPCNCPNQYYKYVNIEGNKLYYFQPQSSNIIIFHDGFFFPISHTTVSSVFIDVTFKTMTTPTISSTSTSKTSISSAASPTSSPGVPLTMTSPALSSTLSTRLLSAAPSTQSTLLPSSTTKLMPTTLRPNPSSLTTSALTESPSPIFSALSTAKTSPLPSSTSFPFSTVPLTILSTLQPCKSAFSPSYCSACSSQFLPLFPTSQHKPCSVHLPSASLMFCFVIIRAGSTHCGMLHTLLPTCMPEGFSMRTAHLFCYFFLALPLSTELCFLYAASTHKMTTVPHIVPSVTTEKTTPTVSATSTSKTSISSEASPTSSPEVPLTTTSSAPSSTLSTSLPSTAPSTLFSTLLPTSTPKSTPTTLRPKLSPLTTSAPTESPTPASSTLSTAKTSLLPSSASSPFSTISSTVRTTSLPGMYSSCSSRWCVCSSQFSPYIPTIQHTPLCCFPPLPIGFSTVTLGTCGELLGLCCDSGWGGTSFLPWSPFSMREHPACVGAGRQCPVPHQVDELLLHALHKTVSKSIPEQNLKGCILILPDPPSLPNRLNVENMVFSAACSCCRPLQLHKEKFQLPCEDPDNPGKRLTKEITVFGGCVCNFDSCIQ", "length": 1764, "header": "tr|A0A8V0ZRJ7-1|A0A8V0ZRJ7_CHICK Isoform 1 of Mucin 6, oligomeric mucus/gel-forming OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZRJ7-1" }, "locus": { "chromosome": "5", "start_pos": 14695530, "end_pos": 14658166, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059133.1", "url": "https://www.ensembl.org/id/ENSGALT00010059133.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036085.1", "url": "https://www.ensembl.org/id/ENSGALP00010036085.1" } ] } }, { "isoform_ac": "A0A8V0ZWS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7/entry#A0A8V0ZWS2-1", "sequence": { "sequence": "NIKRWSYISLFMIHFNLLMSVLGLSPFFSFIVLSKDSCSTWGGGHFSTFDKYQYDFTGTCNYIFATVCDESSPDFNIQFRRGLDKKIARIIIELGPSVIIVEKDSISVRSVGVIKLPYASNGIQIAPYGRSVRLVAKLMEMELVVMWNNEDYLMVLTEKKYMGKTCGMCGNYDGYELNDFVSEGKLLDTYKFAALQKMDDPSEICLSEEISIPAIPHKKYAVICSQLLNLVSPTCSVPKDGFVTRCQLDMQDCSEPGQKNCTCSTLSEYSRQCAMSHQVVFNWRTENFCSVGKCSANQIYEECGSPCIKTCSNPEYSCSSHCTYGCFCPEGTVLDDISKNRTCVHLEQCPCTLNGETYAPGDTMKAACRTCKCTMGQWNCKELPCPGRCSLEGGSFVTTFDSRSYRFHGVCTYILMKSSSLPHNGTLMAIYEKSGYSHSETSLSAIIYLSTKDKIVISQNELLTDDDELKRLPYKSGKETRRYRMKHRPLCLCGNYNGDTTDDFMTSMDITEGTASLFVDSWRAGNCLPAMERETDPCALSQLNKISAETHCSILTKKGTVFETCHAVVNPTPFYKRCVYQACNYEETFPYICSALGSYARTCSSMGLILENWRNSMDNCTITCTGNQTFSYNTQACERTCLSLSNPTLECHPTDIPIEGCNCPKGMYLNHKNECVRKSHCPCYLEDRKYILPDQSTMTGGITCYCVNGRLSCTGKLQNPAESCKAPKKYISCSDSLENKYGATCAPTCQMLATGIECIPTKCESGCVCADGLYENLDGRCVPPEECPCEYGGLSYGKGEQIQTECEICTCRKGKWKCVQKSRCSSTCNLYGEGHITTFDGQRFVFDGNCEYILAMDGCNVNRPLSSFKIVTENVICGKSGVTCSRSISIYLGNLTIILRDETYSISGKNLQVKYNVKKNALHLMFDIIIPGKYNMTLIWNKHMNFFIKISRETQETICGLCGNYNGNMKDDFETRSKYVASNELEFVNSWKENPLCGDVYFVVDPCSKNPYRKAWAEKTCSIINSQVFSACHNKVNRMPYYEACVRDSCGCDIGGDCECMCDAIAVYAMACLDKGICIDWRTPEFCPVYCEYYNSHRKTGSGGAYSYGSSVNCTWHYRPCNCPNQYYKYVNIEGNKLYYFQPQSSNIIIFHDGFFFPISHTTVTFFAATSTLKTTTVLHMVPYIITEMTTPTISSTSTSKTSISSAASPTSSPGVPLTMTSPALSSTLSTRLLSAAPSTQSTLLPSSTTKLMPTTLRPNPSSLTTSALTESPSPIFSALSTAKTSPLPSSTSFPFSTVPLTILSTLQPCKSAFSPSYCSACSSQFLPLFPTSQHKPCSVHLPCCYHPPYLLLLSLLFLGHILMFCFVIIRAGSTAHCGMLHTLLPTCMPEGFSMRTAHLFCYFFLALPLSTELCFLYAASTHKMTTVPHIVPSVTTEKTTPTVSATSTSKTSISSEASPTSSPEVPLTTTSSAPSSTLSTSLPSTAPSTLFSTLLPTSTPKSTPTTLRPKLSPLTTSAPTESPTPASSTLSTAKTSLLPSSASSPFSTISSTVRTTSLPGMYSSCSSRWCVCSSQFSPYIPTIQHTPLCCFPPLPIGFSTVTLGTCGELLGLCCDSGWGGTSFLPWSPFSMREHPACVGHQVDELLLHALHKTVSKSIPEQNLKGCILILPDPPSLPNRLNVENMVFSAACSCCRPLQLHKEKFQLPCEDPDNPGKRLTKEITVFGGCVCNFDSCIQ", "length": 1738, "header": "tr|A0A8V0ZWS2-1|A0A8V0ZRJ7_CHICK Computationally mapped isoform of Mucin 6, oligomeric mucus/gel-forming OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0ZRJ7-1" }, "locus": { "chromosome": "5", "start_pos": 14695530, "end_pos": 14657796, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059140.1", "url": "https://www.ensembl.org/id/ENSGALT00010059140.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036092.1", "url": "https://www.ensembl.org/id/ENSGALP00010036092.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1246, "start_aa": "Thr", "end_pos": 1246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1246", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1543, "start_aa": "Thr", "end_pos": 1543, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1543", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-913709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-913709", "resource": "Reactome", "description": "O-linked glycosylation of mucins" }, { "id": "R-GGA-977068", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-977068", "resource": "Reactome", "description": "Termination of O-glycan biosynthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intestinal cholesterol absorption", "id": "GO:0030299", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030299", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7" } ], "pmid": "" }, { "name": "cholesterol homeostasis", "id": "GO:0042632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7" } ], "pmid": "" }, { "name": "macrophage activation involved in immune response", "id": "GO:0002281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "extracellular matrix structural constituent", "id": "GO:0005201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7" } ], "pmid": "" }, { "name": "virion binding", "id": "GO:0046790", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046790", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1161, "end_pos": 1163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" }, { "start_pos": 682, "end_pos": 684, "annotation": "n_glycosylation_sequon" }, { "start_pos": 942, "end_pos": 944, "annotation": "n_glycosylation_sequon" }, { "start_pos": 983, "end_pos": 985, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRJ7" }, { "id": "PS51233", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51233" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFD", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 229, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1246, 1543 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1161, "end_pos": 1163 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 674, "end_pos": 676 }, { "start_pos": 682, "end_pos": 684 }, { "start_pos": 942, "end_pos": 944 }, { "start_pos": 983, "end_pos": 985 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { 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] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSGSPTHGVWLPPLCPPAPPPQGGSCWLPVNGERCRAKRAVVAPSSWGVPCRGRGQPDPPGRVGTALPPNGPPITTTCVPLCYSDSDAVLLCFDVSRPETLDSASKKTEILDYCPNTRLLLIGCKTDLRTDLSMCWSCPTKSRPRQLGAESYLECSAFTSEKSVHSIFRPPVPPGVSPSALLHLPTRSELISSAFKKEKAKSCSVM", "length": 207, "header": "tr|A0A8V0ZRK3-1|A0A8V0ZRK3_CHICK Isoform 1 of Rho family GTPase 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZRK3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3/entry#A0A8V0ZRK3-1", "sequence": { "sequence": "MGSGSPTHGVWLPPLCPPAPPPQGGSCWLPVNGERCRAKRAVVAPSSWGVPCRGRGQPDPPGRVGTALPPNGPPITTTCVPLCYSDSDAVLLCFDVSRPETLDSASKKTEILDYCPNTRLLLIGCKTDLRTDLSMCWSCPTKSRPRQLGAESYLECSAFTSEKSVHSIFRPPVPPGVSPSALLHLPTRSELISSAFKKEKAKSCSVM", "length": 207, "header": "tr|A0A8V0ZRK3-1|A0A8V0ZRK3_CHICK Isoform 1 of Rho family GTPase 1 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZRK3-1" }, "locus": { "chromosome": "34", "start_pos": 48404, "end_pos": 45784, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055286.1", "url": "https://www.ensembl.org/id/ENSGALT00010055286.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033457.1", "url": "https://www.ensembl.org/id/ENSGALP00010033457.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3" } ], "pmid": "" }, { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3" } ], "pmid": "" }, { "name": "negative regulation of cell adhesion", "id": "GO:0007162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3" } ], "pmid": "" }, { "name": "neuron remodeling", "id": "GO:0016322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016322", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRK9-1", "uniprot_ac": "A0A8V0ZRK9", "uniprot_id": "A0A8V0ZRK9_CHICK", "mass": { "chemical_mass": 33320.0, "monoisotopic_mass": 33320.0 }, "refseq": {}, "gene_names": [ { "name": "MDK", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK9" } ] } ], "protein_names": [ { "name": "Midkine", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRK9", "database": "UniProtKB", "url": 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"chromosome": "5", "start_pos": 23180341, "end_pos": 23182988, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023136", "url": "https://www.ensembl.org/id/ENSGALG00010023136" } ] } } ], "crossref": [ { "id": "A0A8V0ZRK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRK4", "url": "https://www.orthodb.org/?gene=A0A8V0ZRK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRK9", "url": "https://www.orthodb.org/?gene=A0A8V0ZRK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13850", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13850", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13850:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13850:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05196", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05196", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-201556", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-2979096", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2979096", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9851151", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9851151", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0ZRK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VPSSGRRDWGLEEPARSWGEVVVVGPSVTAEGEGGADGAVFAVRRAPGLSAKGLSEPRTALQRSDAETEGHKDAPRRGLEPPTARPSRAAQPLPAEQLPQPPGPPLGPPPAFVAGRAAGGQRRGLHGDFGLRPPRAAGGARRQGPLCCAARGSARGRHTKATAPLRALRAAGRMHPRGLLLLLALLLLAAAAEAAKAKKEKMKKEGSECQDWHWGPCIPNSKDCGLGYREGSCGDESRKLKCKIPCNWKKKFGADCKYKFESWGGCSAQTGVKTRSGILKKALYNAECEEVVYVSKPCTAKMKAKAKAKKGKGKD", "length": 315, "header": "tr|A0A8V0ZRK9-1|A0A8V0ZRK9_CHICK Isoform 1 of Midkine OS=Gallus gallus OX=9031 GN=MDK PE=3 SV=1 CANONICAL=A0A8V0ZRK9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK9/entry#A0A8V0ZRK4-1", "sequence": { "sequence": "MGAGGARSLVGRGGGGGPVRDGRRRRRRRRGRVCGPQSPGAQRQRALGAPDRSAALGRGDRGTQGRPSQGARAPDSPAEPSRAAPPRRAAPPASGAAPRPAARLCGWPCCRGAEEGLARGLWAPTTSGCRRGSTSGAAVLRCAGLRTRPPHKGNGAAPRPPRRSKDCGLGYREGSCGDESRKLKCKIPCNWKKKFGADCKYKFESWGGCSAQTGVKTRSGILKKALYNAECEEVVYVSKPCTAKMKAKAKAKKGKGKD", "length": 258, "header": "tr|A0A8V0ZRK4-1|A0A8V0ZRK9_CHICK Computationally mapped isoform of Midkine OS=Gallus gallus OX=9031 GN=MDK PE=3 SV=2 CANONICAL=A0A8V0ZRK9-1" }, "locus": { "chromosome": "5", "start_pos": 23182766, "end_pos": 23180652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056385.1", "url": "https://www.ensembl.org/id/ENSGALT00010056385.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034142.1", "url": "https://www.ensembl.org/id/ENSGALP00010034142.1" } ] } }, { "isoform_ac": "A0A8V0ZRK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK9/entry#A0A8V0ZRK9-1", "sequence": { "sequence": "VPSSGRRDWGLEEPARSWGEVVVVGPSVTAEGEGGADGAVFAVRRAPGLSAKGLSEPRTALQRSDAETEGHKDAPRRGLEPPTARPSRAAQPLPAEQLPQPPGPPLGPPPAFVAGRAAGGQRRGLHGDFGLRPPRAAGGARRQGPLCCAARGSARGRHTKATAPLRALRAAGRMHPRGLLLLLALLLLAAAAEAAKAKKEKMKKEGSECQDWHWGPCIPNSKDCGLGYREGSCGDESRKLKCKIPCNWKKKFGADCKYKFESWGGCSAQTGVKTRSGILKKALYNAECEEVVYVSKPCTAKMKAKAKAKKGKGKD", "length": 315, "header": "tr|A0A8V0ZRK9-1|A0A8V0ZRK9_CHICK Isoform 1 of Midkine OS=Gallus gallus OX=9031 GN=MDK PE=3 SV=1 CANONICAL=A0A8V0ZRK9-1" }, "locus": { "chromosome": "5", "start_pos": 23182789, "end_pos": 23180652, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056393.1", "url": "https://www.ensembl.org/id/ENSGALT00010056393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034147.1", "url": "https://www.ensembl.org/id/ENSGALP00010034147.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-201556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-201556", "resource": "Reactome", "description": "Signaling by ALK" }, { "id": "R-GGA-2979096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2979096", "resource": "Reactome", "description": "NOTCH2 Activation and Transmission of Signal to the Nucleus" }, { "id": "R-GGA-9851151", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9851151", "resource": "Reactome", "description": "MDK and PTN in ALK signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK9" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of cell division", "id": "GO:0051781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051781", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRK9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK9" }, { "id": "PF01091", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01091" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pleiotrophin/Midkine C-terminal", "eco_id": "ECO_0000259", "start_pos": 253, "end_pos": 314, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0ZRK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRK9" }, { "id": "PF05196", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05196" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pleiotrophin/Midkine N-terminal", "eco_id": "ECO_0000259", "start_pos": 196, "end_pos": 252, "start_aa": "Lys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRL8-1", "uniprot_ac": "A0A8V0ZRL8", "uniprot_id": "A0A8V0ZRL8_CHICK", "mass": { "chemical_mass": 49018.0, "monoisotopic_mass": 49018.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "J domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL8", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZRL8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRL8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR43999", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43999", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43999:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43999:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZRL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRGAHEGQLTAVTGALTAASVLCQVEPVGRWFEAFIKRRNINVSASFQELEDEKELSEESGDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGNIRYRATQKQIKAAHKSMVLKHHPDKRKAAGEQIGEGDNDYFTCITKAYEILSDPVKRRAFNSIDPTFDNSVPSKSEAKENFFEVFSPVFERNARWSNKKNVPKLGDVNSSFEEVDAFYSFWYNFDPERVRTTPEIWQKLTRAAPDRYAPTLLATFHRYEDQQRRPLVFELILTLQNYEQHLPPTHVSISAVTELANRLGDVEEQMSLLINRDEPVEPVIVSETFDDEQDKQRGLMKELIKLMKIQLIKEDGSPSSPVTSKISATEGKRFPARVRNNNRTASRVALWRYLRDHGEDMRKWHDQDTPVLRARVRELQNRPTTSVVAPVTTGNE", "length": 426, "header": "tr|A0A8V0ZRL8-1|A0A8V0ZRL8_CHICK Isoform 1 of J domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZRL8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL8/entry#A0A8V0ZRL8-1", "sequence": { "sequence": "MLRGAHEGQLTAVTGALTAASVLCQVEPVGRWFEAFIKRRNINVSASFQELEDEKELSEESGDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGNIRYRATQKQIKAAHKSMVLKHHPDKRKAAGEQIGEGDNDYFTCITKAYEILSDPVKRRAFNSIDPTFDNSVPSKSEAKENFFEVFSPVFERNARWSNKKNVPKLGDVNSSFEEVDAFYSFWYNFDPERVRTTPEIWQKLTRAAPDRYAPTLLATFHRYEDQQRRPLVFELILTLQNYEQHLPPTHVSISAVTELANRLGDVEEQMSLLINRDEPVEPVIVSETFDDEQDKQRGLMKELIKLMKIQLIKEDGSPSSPVTSKISATEGKRFPARVRNNNRTASRVALWRYLRDHGEDMRKWHDQDTPVLRARVRELQNRPTTSVVAPVTTGNE", "length": 426, "header": "tr|A0A8V0ZRL8-1|A0A8V0ZRL8_CHICK Isoform 1 of J domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZRL8-1" }, "locus": { "chromosome": "14", "start_pos": 3663130, "end_pos": 3661853, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010054958.1", "url": "https://www.ensembl.org/id/ENSGALT00010054958.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033228.1", "url": "https://www.ensembl.org/id/ENSGALP00010033228.1" } ] } } ], "glycosylation": [], 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], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL8" } ], "pmid": "" }, { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRL8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRL8" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 159, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 203, "end_pos": 205 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRP5-1", "uniprot_ac": "A0A8V0ZRP5", "uniprot_id": "A0A8V0ZRP5_CHICK", "mass": { "chemical_mass": 101585.0, "monoisotopic_mass": 101585.0 }, "refseq": {}, "gene_names": [ { "name": "ADGRD1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5" } ] } ], "protein_names": [ { "name": "Adhesion G-protein coupled receptor D1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 133", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Adhesion G-protein coupled receptor (aGPCR) for androgen hormone 5alpha-dihydrotestosterone (5alpha-DHT), also named 17beta-hydroxy-5alpha-androstan-3-one, the most potent hormone among androgens. Also activated by methenolone drug. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRD1 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. Acts as a 5alpha-DHT receptor in muscle cells, thereby increasing intracellular cyclic AMP (cAMP) levels and enhancing muscle strength.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP0#function" }, { "database": "UniProtKB", "id": "ARBA00093338", "url": "https://www.uniprot.org/uniprotkb/ARBA00093338#function" }, { "database": "UniProtKB", "id": "A0A8V0ZRM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZRP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZTM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTM6#function" }, { "database": "UniProtKB", "id": "A0A8V0ZTN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN1#function" }, { "database": "UniProtKB", "id": "A0A8V0ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ADGRD1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5", "locus": { "chromosome": "15", "start_pos": 3080114, "end_pos": 3201287, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010023149", "url": "https://www.ensembl.org/id/ENSGALG00010023149" } ] } } ], "crossref": [ { "id": "A0A8V0ZRP5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15256", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15256", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRM5", "url": "https://www.orthodb.org/?gene=A0A8V0ZRM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRP0", "url": "https://www.orthodb.org/?gene=A0A8V0ZRP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRP5", "url": "https://www.orthodb.org/?gene=A0A8V0ZRP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTM6", "url": "https://www.orthodb.org/?gene=A0A8V0ZTM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTN1", "url": "https://www.orthodb.org/?gene=A0A8V0ZTN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZTN7", "url": "https://www.orthodb.org/?gene=A0A8V0ZTN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011:SF216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011:SF216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZRM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRP0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTM6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTN7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZTN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZTN7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGCNLLFPQKFLAVSMFAWILTIVLVYGNYSQLLEHPGFKVFSSASHYWPLEDVDGIHEFRDTNGALRIHNFTVLPSHNSTFVYTNDSAYSNFSATVDIVEGMVNKGIYVTEKKGVTFLFFGRYQNSCISNPEVCGPEGVTFSFFWKTQDQQTKFPPASGGQVISSGFKICSSEGEGSVEFYTRGNAMMKWKASFSPPGPYWTHILFTWKSREGLKVYVNGTLNTTDPDGKVFYDYGDPSANLLTGTEGDQTKRYVNGAFDEFIIWERALTPNEIEQYFTAAIGVQFLLSSTLSWSTMTTTTKPVLSTNAYHPIITNLTKERGNFHSSDILLEYLENVSFSLPNKSLSENTALSLTEAFLKVIEDFLLLPNWLEIPETAHIFGSLIQTIDSVMVHMTRNLEENSLSLTVEGSSSVADYTLAKMHPKTLNLSHYRFPSRGQSFISIPSEAFQERAWITIVGMFYHNMHYYFHSINPMDTKIAEAAAYKGYMISAASYLISIKVDPPPKLSHNLSGSPLITIQLTHRLTPRQYSLALNKSNRVHLYCAFLDYSNGTGVWSNEGCVRDSGDLNYSVCLCNHLTNFAILMQVVPLKLTREHQVALSSITYIGCALSIFCLTITLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQILLVTSFQFSPGTVPCKILAILLHFFFLSAFAWMLVEGFHLYSMVIKVFGSEESKHLYYYGIGWGCPLVICVISATSSLDSYGESDNCWLSLENGAIWAFVAPALFVILVNIGILIAVTRVISRISADNYKVHGDANAFKLTAKAVAVLLPILGSSWIFGILAINAHTLIFQYMFAVFNSLQGFFMFLFHCLLNSEVRAAFKHKTKVWSLTSSSARNINVKPFNSDIMSGNRPGTTPTKLNTWDKSTNSANRIDLSAV", "length": 910, "header": "tr|A0A8V0ZRP5-1|A0A8V0ZRP5_CHICK Isoform 1 of Adhesion G-protein coupled receptor D1 OS=Gallus gallus OX=9031 GN=ADGRD1 PE=3 SV=1 CANONICAL=A0A8V0ZRP5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5/entry#A0A8V0ZRM5-1", "sequence": { "sequence": "MEEAEAEELLYRGFKVFSSASHYWPLEDVDGIHEFRDTNGDIVEGMVNKGIYVTEKKGVTFLFFGRYQNSCISNPEVCGPEGVTFSFFWKTQDQQTKFPPASGGQVISSGFKICSSEGEGSVEFYTRGNAMMKWKASFSPPGPYWTHILFTWKSREGLKVYVNGTLNTTDPDGKVFYDYGDPSANLLTGTEGDQTKRYVNGAFDEFIIWERALTPNEIEQYFTAAIGVQFLLSSTLSWSTMTTTTKPVLSTNAYHPIITNLTKERGNFHSSDILLEYLENVSFSLPNKSLSENTALSLTEAFLKVIEDFLLLPNWLEIPETAHIFGSLIQTIDSVMVHMTRNLEENSLSLTVEGSSSVADYTLAKMHPKTLNLSHYRFPSRGQSFISIPSEAFQERAWITIVGMFYHNMHYYFHSINPMDTKIAEAAAYKGYMISAASYLISIKVDPPPKLSHNLSGSPLITIQLTHRLTPRQYSLALNKSNRVHLYCAFLDYSNGTGVWSNEGCVRDSGDLNYSVCLCNHLTNFAILMQVVPLKLTREHQVALSSITYIGCALSIFCLTITLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQILLVTSFQFSPGTVPCKILAILLHFFFLSAFAWMLVEGFHLYSMVIKVFGSEESKHLYYYGIGWGCPLVICVISATSSLDSYGESDNCWLSLENGAIWAFVAPALFVILVNIGILIAVTRVISRISADNYKVHGDANAFKLTAKAVAVLLPILGSSWIFGILAINAHTLIFQYMFAVFNSLQGFFMFLFHCLLNSEVRAAFKHKTKVWSLTSSSARNINVKPFNSDIMSGNRPGTTPTKLNTWDKSTNSANRIDLSAV", "length": 852, "header": "tr|A0A8V0ZRM5-1|A0A8V0ZRP5_CHICK Computationally mapped isoform of Adhesion G-protein coupled receptor D1 OS=Gallus gallus OX=9031 GN=ADGRD1 PE=3 SV=1 CANONICAL=A0A8V0ZRP5-1" }, "locus": { "chromosome": "15", "start_pos": 3194786, "end_pos": 3080353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056423.1", "url": "https://www.ensembl.org/id/ENSGALT00010056423.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034168.1", "url": "https://www.ensembl.org/id/ENSGALP00010034168.1" } ] } }, { "isoform_ac": "A0A8V0ZRP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5/entry#A0A8V0ZRP0-1", "sequence": { "sequence": "MIENLQEFDLGCTSNLTLTMKNLLSLLCCRYSLLILFQFKYQVYGNYSQLLEHPDIVEGMVNKGIYVTEKKGVTFLFFGRYQNSCISNPEVCGPEGVTFSFFWKTQDQQTKFPPASGGQVISSGFKICSSEGEGSVEFYTRGNAMMKWKASFSPPGPYWTHILFTWKSREGLKVYVNGTLNTTDPDGKVFYDYGDPSANLLTGTEGDQTKRYVNGAFDEFIIWERALTPNEIEQYFTAAIGVQFLLSSTLSWSTMTTTTKPVLSTNAYHPIITNLTKERGNFHSSDILLEYLENVSFSLPNKSLSENTALSLTEAFLKVIEDFLLLPNWLEIPETAHIFGSLIQTIDSVMVHMTRNLEENSLSLTVEGSSSVADYTLAKMHPKTLNLSHYRFPSRGQSFISIPSEAFQERAWITIVGMFYHNMHYYFHSINPMDTKIAEAAAYKGYMISAASYLISIKVDPPPKLSHNLSGSPLITIQLTHRLTPRQYSLALNKSNRVHLYCAFLDYSNGTGVWSNEGCVRDSGDLNYSVCLCNHLTNFAILMQVVPLKLTREHQVALSSITYIGCALSIFCLTITLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQILLVTSFQFSPGTVPCKILAILLHFFFLSAFAWMLVEGFHLYSMVIKVFGSEESKHLYYYGIGWGCPLVICVISATSSLDSYGESDNCWLSLENGAIWAFVAPALFVILVNIGILIAVTRVISRISADNYKVHGDANAFKLTAKAVAVLLPILGSSWIFGILAINAHTLIFQYMFAVFNSLQGFFMFLFHCLLNSEVRAAFKHKTKVWSLTSSSARNINVKPFNSDIMSGNRPGTTPTKLNTWDKSTNSANRIDLSAV", "length": 866, "header": "tr|A0A8V0ZRP0-1|A0A8V0ZRP0_CHICK Computationally mapped isoform of Adhesion G-protein coupled receptor D1 OS=Gallus gallus OX=9031 GN=ADGRD1 PE=3 SV=1 CANONICAL=A0A8V0ZRP5-1" }, "locus": { "chromosome": "15", "start_pos": 3198938, "end_pos": 3080353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056445.1", "url": "https://www.ensembl.org/id/ENSGALT00010056445.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034188.1", "url": "https://www.ensembl.org/id/ENSGALP00010034188.1" } ] } }, { "isoform_ac": "A0A8V0ZRP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5/entry#A0A8V0ZRP5-1", "sequence": { "sequence": "MSGCNLLFPQKFLAVSMFAWILTIVLVYGNYSQLLEHPGFKVFSSASHYWPLEDVDGIHEFRDTNGALRIHNFTVLPSHNSTFVYTNDSAYSNFSATVDIVEGMVNKGIYVTEKKGVTFLFFGRYQNSCISNPEVCGPEGVTFSFFWKTQDQQTKFPPASGGQVISSGFKICSSEGEGSVEFYTRGNAMMKWKASFSPPGPYWTHILFTWKSREGLKVYVNGTLNTTDPDGKVFYDYGDPSANLLTGTEGDQTKRYVNGAFDEFIIWERALTPNEIEQYFTAAIGVQFLLSSTLSWSTMTTTTKPVLSTNAYHPIITNLTKERGNFHSSDILLEYLENVSFSLPNKSLSENTALSLTEAFLKVIEDFLLLPNWLEIPETAHIFGSLIQTIDSVMVHMTRNLEENSLSLTVEGSSSVADYTLAKMHPKTLNLSHYRFPSRGQSFISIPSEAFQERAWITIVGMFYHNMHYYFHSINPMDTKIAEAAAYKGYMISAASYLISIKVDPPPKLSHNLSGSPLITIQLTHRLTPRQYSLALNKSNRVHLYCAFLDYSNGTGVWSNEGCVRDSGDLNYSVCLCNHLTNFAILMQVVPLKLTREHQVALSSITYIGCALSIFCLTITLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQILLVTSFQFSPGTVPCKILAILLHFFFLSAFAWMLVEGFHLYSMVIKVFGSEESKHLYYYGIGWGCPLVICVISATSSLDSYGESDNCWLSLENGAIWAFVAPALFVILVNIGILIAVTRVISRISADNYKVHGDANAFKLTAKAVAVLLPILGSSWIFGILAINAHTLIFQYMFAVFNSLQGFFMFLFHCLLNSEVRAAFKHKTKVWSLTSSSARNINVKPFNSDIMSGNRPGTTPTKLNTWDKSTNSANRIDLSAV", "length": 910, "header": "tr|A0A8V0ZRP5-1|A0A8V0ZRP5_CHICK Isoform 1 of Adhesion G-protein coupled receptor D1 OS=Gallus gallus OX=9031 GN=ADGRD1 PE=3 SV=1 CANONICAL=A0A8V0ZRP5-1" }, "locus": { "chromosome": "15", "start_pos": 3201081, "end_pos": 3080353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056450.1", "url": "https://www.ensembl.org/id/ENSGALT00010056450.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034193.1", "url": "https://www.ensembl.org/id/ENSGALP00010034193.1" } ] } }, { "isoform_ac": "A0A8V0ZTM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5/entry#A0A8V0ZTM6-1", "sequence": { "sequence": "MIENLQEFDLGCTSNLTLTMKNLLSLLCCRYSLLILFQFKYQVYGNYSQLLEHPALRIHNFTVLPSHNSTFVYTNDSAYSNFSATVDIVEGMVNKGIYVTEKKGVTFLFFGRYQNSCISNPEVCGPEGVTFSFFWKTQDQQTKFPPASGGQVISSGFKICSSEGEGSVEFYTRGNAMMKWKASFSPPGPYWTHILFTWKSREGLKVYVNGTLNTTDPDGKVFYDYGDPSANLLTGTEGDQTKRYVNGAFDEFIIWERALTPNEIEQYFTAAIGVQFLLSSTLSWSTMTTTTKPVLSTNAYHPIITNLTKERGNFHSSDILLEYLENVSFSLPNKSLSENTALSLTEAFLKVIEDFLLLPNWLEIPETAHIFGSLIQTIDSVMVHMTRNLEENSLSLTVEGSSSVADYTLAKMHPKTLNLSHYRFPSRGQSFISIPSEAFQERAWITIVGMFYHNMHYYFHSINPMDTKIAEAAAYKGYMISAASYLISIKVDPPPKLSHNLSGSPLITIQLTHRLTPRQYSLALNKSNRVHLYCAFLDYSNGTGVWSNEGCVRDSGDLNYSVCLCNHLTNFAILMQVVPLKLTREHQVALSSITYIGCALSIFCLTITLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQILLVTSFQFSPGTVPCKILAILLHFFFLSAFAWMLVEGFHLYSMVIKVFGSEESKHLYYYGIGWGCPLVICVISATSSLDSYGESDNCWLSLENGAIWAFVAPALFVILVNIGILIAVTRVISRISADNYKVHGDANAFKLTAKAVAVLLPILGSSWIFGILAINAHTLIFQYMFAVFNSLQGFFMFLFHCLLNSEVRAAFKHKTKVWSLTSSSARNINVKPFNSDIMSGNRPGTTPTKLNTWDKSTNSANRIDLSAV", "length": 898, "header": "tr|A0A8V0ZTM6-1|A0A8V0ZRP5_CHICK Computationally mapped isoform of Adhesion G-protein coupled receptor D1 OS=Gallus gallus OX=9031 GN=ADGRD1 PE=3 SV=1 CANONICAL=A0A8V0ZRP5-1" }, "locus": { "chromosome": "15", "start_pos": 3198938, "end_pos": 3080353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056432.1", "url": "https://www.ensembl.org/id/ENSGALT00010056432.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034175.1", "url": "https://www.ensembl.org/id/ENSGALP00010034175.1" } ] } }, { "isoform_ac": "A0A8V0ZTN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5/entry#A0A8V0ZTN1-1", "sequence": { "sequence": "METTPSYSNTQGSKFSHQLPITGRWKTWMEFMSFGIRMEVDKGFIDSGNNISICAVYIVEGMVNKGIYVTEKKGVTFLFFGRYQNSCISNPEVCGPEGVTFSFFWKTQDQQTKFPPASGGQVISSGFKICSSEGEGSVEFYTRGNAMMKWKASFSPPGPYWTHILFTWKSREGLKVYVNGTLNTTDPDGKVFYDYGDPSANLLTGTEGDQTKRYVNGAFDEFIIWERALTPNEIEQYFTAAIGVQFLLSSTLSWSTMTTTTKPVLSTNAYHPIITNLTKERGNFHSSDILLEYLENVSFSLPNKSLSENTALSLTEAFLKVIEDFLLLPNWLEIPETAHIFGSLIQTIDSVMVHMTRNLEENSLSLTVEGSSSVADYTLAKMHPKTLNLSHYRFPSRGQSFISIPSEAFQERAWITIVGMFYHNMHYYFHSINPMDTKIAEAAAYKGYMISAASYLISIKVDPPPKLSHNLSGSPLITIQLTHRLTPRQYSLALNKSNRVHLYCAFLDYSNGTGVWSNEGCVRDSGDLNYSVCLCNHLTNFAILMQVVPLKLTREHQVALSSITYIGCALSIFCLTITLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQILLVTSFQFSPGTVPCKILAILLHFFFLSAFAWMLVEGFHLYSMVIKVFGSEESKHLYYYGIGWGCPLVICVISATSSLDSYGESDNCWLSLENGAIWAFVAPALFVILVNIGILIAVTRVISRISADNYKVHGDANAFKLTAKAVAVLLPILGSSWIFGILAINAHTLIFQYMFAVFNSLQGFFMFLFHCLLNSEVRAAFKHKTKVWSLTSSSARNINVKPFNSDIMSGNRPGTTPTKLNTWDKSTNSANRIDLSAV", "length": 868, "header": "tr|A0A8V0ZTN1-1|A0A8V0ZRP5_CHICK Computationally mapped isoform of Adhesion G-protein coupled receptor D1 OS=Gallus gallus OX=9031 GN=ADGRD1 PE=3 SV=1 CANONICAL=A0A8V0ZRP5-1" }, "locus": { "chromosome": "15", "start_pos": 3198711, "end_pos": 3080353, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056437.1", "url": "https://www.ensembl.org/id/ENSGALT00010056437.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034180.1", "url": "https://www.ensembl.org/id/ENSGALP00010034180.1" } ] } }, { "isoform_ac": "A0A8V0ZTN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP5/entry#A0A8V0ZTN7-1", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRP4-1", "uniprot_ac": "A0A8V0ZRP4", "uniprot_id": "A0A8V0ZRP4_CHICK", "mass": { "chemical_mass": 36781.0, "monoisotopic_mass": 36781.0 }, "refseq": { "ac": "NP_001382922", "name": "renalase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382922" }, "gene_names": [ { "name": "RNLS", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4" } ] }, { "name": "C10orf59", "type": "synonym", "evidence": [ { "id": "NP_001382922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382922" } ] }, { "name": "RNLS", "type": "synonym", "evidence": [ { "id": "NP_001382922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382922" } ] }, { "name": "renalase", "type": "synonym", "evidence": [ { "id": "NP_001382922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382922" } ] } ], "protein_names": [ { "name": "Renalase, FAD-dependent amine oxidase", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4/entry#names_and_taxonomy" } ] }, { "name": "renalase", "type": "synonym", "evidence": [ { "id": "NP_001382922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382922" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BX935542.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992531, SAMEA103992604 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX935542.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001382922", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382922" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RNLS", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4", "locus": { "chromosome": "6", "start_pos": 10204578, "end_pos": 10141794, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010022599", "url": "https://www.ensembl.org/id/ENSGALG00010022599" } ] } } ], "crossref": [ { "id": "A0A8V0ZRP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "423674", "url": "https://www.ncbi.nlm.nih.gov/gene/423674", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRP4", "url": "https://www.orthodb.org/?gene=A0A8V0ZRP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23357", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23357", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23357:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23357:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01593", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01593", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-196807", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196807", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001382922", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382922", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARVLVVGAGLTGSSCAALLRGATRERVSVWDKARGAGGRMSTSRSARDAACTADLGAQYVSRSAGSRGSFYEELLSHGILKPLSARIEGLVEKEGSCDYVAPQGISSVVKYFLRQSGADVFYEHHVTHITLRDGKWEVSRKMGSPELFDVVILTIPVPQILQLQGDIVNIINERQKQQLESASYSSRYALGLFYEVGARIDVPWAAKYITDNPCIRFISIDNKKRNIDSPEIGPSVVVHTTVTFGREHLDSDPAEVQQLILSHLESLVPSLPKAASVKCQKWRYSQVTKAVPNCPGQMILHTQPLLICGGDGFTCSNFDGCIESAMSLAETVRSHL", "length": 337, "header": "tr|A0A8V0ZRP4-1|A0A8V0ZRP4_CHICK Isoform 1 of Renalase, FAD-dependent amine oxidase OS=Gallus gallus OX=9031 GN=RNLS PE=4 SV=1 CANONICAL=A0A8V0ZRP4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4/entry#A0A8V0ZRP4-1", "sequence": { "sequence": "MARVLVVGAGLTGSSCAALLRGATRERVSVWDKARGAGGRMSTSRSARDAACTADLGAQYVSRSAGSRGSFYEELLSHGILKPLSARIEGLVEKEGSCDYVAPQGISSVVKYFLRQSGADVFYEHHVTHITLRDGKWEVSRKMGSPELFDVVILTIPVPQILQLQGDIVNIINERQKQQLESASYSSRYALGLFYEVGARIDVPWAAKYITDNPCIRFISIDNKKRNIDSPEIGPSVVVHTTVTFGREHLDSDPAEVQQLILSHLESLVPSLPKAASVKCQKWRYSQVTKAVPNCPGQMILHTQPLLICGGDGFTCSNFDGCIESAMSLAETVRSHL", "length": 337, "header": "tr|A0A8V0ZRP4-1|A0A8V0ZRP4_CHICK Isoform 1 of Renalase, FAD-dependent amine oxidase OS=Gallus gallus OX=9031 GN=RNLS PE=4 SV=1 CANONICAL=A0A8V0ZRP4-1" }, "locus": { "chromosome": "6", "start_pos": 10204432, "end_pos": 10141821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010055000.1", "url": "https://www.ensembl.org/id/ENSGALT00010055000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010033254.1", "url": "https://www.ensembl.org/id/ENSGALP00010033254.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-196807", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-196807", "resource": "Reactome", "description": "Nicotinate metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "monoamine oxidase activity", "id": "GO:0097621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097621", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4" } ], "pmid": "" }, { "name": "epinephrine binding", "id": "GO:0051379", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051379", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on NAD(P)H", "id": "GO:0016651", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016651", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4" } ], "pmid": "" }, { "name": "NADH binding", "id": "GO:0070404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070404", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of blood pressure", "id": "GO:0045776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4" } ], "pmid": "" }, { "name": "negative regulation of heart rate", "id": "GO:0010459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010459", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRP4" }, { "id": "PF01593", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01593" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amine oxidase", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 333, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRS7-1", "uniprot_ac": "A0A8V0ZRS7", "uniprot_id": "A0A8V0ZRS7_CHICK", "mass": { "chemical_mass": 52272.0, "monoisotopic_mass": 52272.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Maestro/Maestro-like HEAT-repeats domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS7", "locus": {} } ], "crossref": [ { "id": "A0A8V0ZRS7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23120:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23120:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZRS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQALLHQLETVPLGQKTEVGVLHTAAATALHKLLQYLEYGPQVRLVFPELFVVLIIQLVSAGPLAPLEITAITEDPFRPSAPTSAIRTVVETAHSLLLCAEMDNLAFSMDTHNLWARLQGTATWQNGLHSLAKVMLKNCRDQCRPIFRHLQNLLQYHQLQWREVPAMAFYFELWSCQGHHEDDTCPQKIFRKYIRSKQPKSRELALRGLRNLYAGRMQLLLPDALLWLQDMRADIKLQAIHLLQDIAAQHPASIRGVLSQLAVQLLSCFNEDNAEVRWRSMELFALLLEAPGRKRLLLQAERSLLPLFIHMNEDIPNVAQAAQKALIHAAKLLGWQQLQRLASAAEVWMIADCLLQKRGRDAEQYLKDTVLHLHSPQVPVRDTAVRFLGLLGRKLRNENREKMSDIRKALEGAKEDSEPAVRCLVLQTLLILSVLEDVPPTRPRLRRWFWRTWRE", "length": 456, "header": "tr|A0A8V0ZRS7-1|A0A8V0ZRS7_CHICK Isoform 1 of Maestro/Maestro-like HEAT-repeats domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZRS7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS7/entry#A0A8V0ZRS7-1", "sequence": { "sequence": "MVQALLHQLETVPLGQKTEVGVLHTAAATALHKLLQYLEYGPQVRLVFPELFVVLIIQLVSAGPLAPLEITAITEDPFRPSAPTSAIRTVVETAHSLLLCAEMDNLAFSMDTHNLWARLQGTATWQNGLHSLAKVMLKNCRDQCRPIFRHLQNLLQYHQLQWREVPAMAFYFELWSCQGHHEDDTCPQKIFRKYIRSKQPKSRELALRGLRNLYAGRMQLLLPDALLWLQDMRADIKLQAIHLLQDIAAQHPASIRGVLSQLAVQLLSCFNEDNAEVRWRSMELFALLLEAPGRKRLLLQAERSLLPLFIHMNEDIPNVAQAAQKALIHAAKLLGWQQLQRLASAAEVWMIADCLLQKRGRDAEQYLKDTVLHLHSPQVPVRDTAVRFLGLLGRKLRNENREKMSDIRKALEGAKEDSEPAVRCLVLQTLLILSVLEDVPPTRPRLRRWFWRTWRE", "length": 456, "header": "tr|A0A8V0ZRS7-1|A0A8V0ZRS7_CHICK Isoform 1 of Maestro/Maestro-like HEAT-repeats domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0ZRS7-1" }, "locus": { "chromosome": "34", "start_pos": 2857691, "end_pos": 2854698, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056488.1", "url": "https://www.ensembl.org/id/ENSGALT00010056488.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034231.1", "url": "https://www.ensembl.org/id/ENSGALP00010034231.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRS7" }, { "id": "PF23227", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23227" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Maestro/Maestro-like HEAT-repeats", "eco_id": "ECO_0000259", "start_pos": 196, "end_pos": 433, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRT1-1", "uniprot_ac": "A0A8V0ZRT1", "uniprot_id": "A0A8V0ZRT1_CHICK", "mass": { "chemical_mass": 45031.0, "monoisotopic_mass": 45031.0 }, "refseq": { "ac": "NP_001186563", "name": "chitinase domain-containing protein 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186563" }, "gene_names": [ { "name": "CHID1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ] }, { "name": "CHID1", "type": "synonym", "evidence": [ { "id": "NP_001186563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186563" } ] }, { "name": "CHIL1", "type": "synonym", "evidence": [ { "id": "NP_001186563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186563" } ] } ], "protein_names": [ { "name": "Chitinase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1/entry#names_and_taxonomy" } ] }, { "name": "chitinase domain-containing protein 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001186563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186563" } ] }, { "name": "chitinase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001186563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186563" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01013542.1, BX932842.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992432 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000214.1. On Sep 23, 2021 this sequence version replaced NP_001186563.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186563" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CHID1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1", "locus": { "chromosome": "5", "start_pos": 14850889, "end_pos": 14744872, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024288", "url": "https://www.ensembl.org/id/ENSGALG00010024288" } ] } } ], "crossref": [ { "id": "A0A8V0ZRT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02876", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02876", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423103", "url": "https://www.ncbi.nlm.nih.gov/gene/423103", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423103", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423103", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSINERI", "url": "https://omabrowser.org/oma/group/YSINERI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRT1", "url": "https://www.orthodb.org/?gene=A0A8V0ZRT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZWZ8", "url": "https://www.orthodb.org/?gene=A0A8V0ZWZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZZ35", "url": "https://www.orthodb.org/?gene=A0A8V0ZZ35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V1A4F2", "url": "https://www.orthodb.org/?gene=A0A8V1A4F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46066", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46066", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46066:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46066:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001186563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWZ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZWZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZZ35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZ35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4F2", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V1A4F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4F2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRFLCISVCLTMICWLAEGTLSKTDAKKAATKKLEEKTLHSDKNVQDRGLVVTDPKAKDIILEHRSYCSKKTKERHFSGDVLGYITPWNSHGYDIAKIFGNKFTLISPVWLQVRRRGKERFQFTGLHDVDKGWMKDVRKNSKNIKIVPRILFDGWTYHDFESVFGSEDEIEELSQSMVLLAKNENFDGFVVEVWSQLGNQKQKELIHLLIHLSEALHEAQLKLILVIPPAVAAGTNQPGMFTKKEFDQLASAVDSFSLMTYDYSTPQRPGPNSPLPWVRACIQVLDPDSKWRNKILLGLNFYGMDYSALGALGEPILGTRYIETLKEHKPKIVWDEQIAEHYFEYKKNKGGKHAIFYPTLKSIQLRLELAKELGTGISIWELGQGLDYFYDLL", "length": 393, "header": "tr|A0A8V0ZRT1-1|A0A8V0ZRT1_CHICK Isoform 1 of Chitinase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CHID1 PE=1 SV=1 CANONICAL=A0A8V0ZRT1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1/entry#A0A8V0ZRT1-1", "sequence": { "sequence": "MRFLCISVCLTMICWLAEGTLSKTDAKKAATKKLEEKTLHSDKNVQDRGLVVTDPKAKDIILEHRSYCSKKTKERHFSGDVLGYITPWNSHGYDIAKIFGNKFTLISPVWLQVRRRGKERFQFTGLHDVDKGWMKDVRKNSKNIKIVPRILFDGWTYHDFESVFGSEDEIEELSQSMVLLAKNENFDGFVVEVWSQLGNQKQKELIHLLIHLSEALHEAQLKLILVIPPAVAAGTNQPGMFTKKEFDQLASAVDSFSLMTYDYSTPQRPGPNSPLPWVRACIQVLDPDSKWRNKILLGLNFYGMDYSALGALGEPILGTRYIETLKEHKPKIVWDEQIAEHYFEYKKNKGGKHAIFYPTLKSIQLRLELAKELGTGISIWELGQGLDYFYDLL", "length": 393, "header": "tr|A0A8V0ZRT1-1|A0A8V0ZRT1_CHICK Isoform 1 of Chitinase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CHID1 PE=1 SV=1 CANONICAL=A0A8V0ZRT1-1" }, "locus": { "chromosome": "5", "start_pos": 14848828, "end_pos": 14748658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059252.1", "url": "https://www.ensembl.org/id/ENSGALT00010059252.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036171.1", "url": "https://www.ensembl.org/id/ENSGALP00010036171.1" } ] } }, { "isoform_ac": "A0A8V0ZWZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1/entry#A0A8V0ZWZ8-1", "sequence": { "sequence": "MRFLCISVCLTMICWLAEGTLSKTDAKKAATKKLEEKTLHSDKNVQDRGLVVTDPKAKDIILEHRSYCSKKTKERHFSGDVLGYITPWNSHGYDIAKIFGNKFTLISPVWLQVRRRGKERFQFTGLHDVDKGWMKDVRKNSKNIKIVPRILFDGWTYHDFESVFGSEDEIEELSQSMVLLAKNENFDGFVVEVWSQLGNQKQKELIHLLIHLSEALHEAQLKLILVIPPAVAAGYIETLKEHKPKIVWDEQIAEHYFEYKKNKGGKHAIFYPTLKSIQLRLELAKELGTGISIWELGQGLDYFYDLL", "length": 307, "header": "tr|A0A8V0ZWZ8-1|A0A8V0ZRT1_CHICK Computationally mapped isoform of Chitinase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CHID1 PE=1 SV=1 CANONICAL=A0A8V0ZRT1-1" }, "locus": { "chromosome": "5", "start_pos": 14848828, "end_pos": 14748658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059255.1", "url": "https://www.ensembl.org/id/ENSGALT00010059255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036173.1", "url": "https://www.ensembl.org/id/ENSGALP00010036173.1" } ] } }, { "isoform_ac": "A0A8V0ZZ35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1/entry#A0A8V0ZZ35-1", "sequence": { "sequence": "MRFLCISVCLTMICWLAEGTLSKTDAKKAATKKLEEKTLHSDKNVQDRGLVVTDPKAKDIILEHRSYCSKKTKERHFSGDVLGYITPWNSHGYDIAKIFGNKFTLISPVWLQVRRRGKERFQFTGLHDVDKGWMKDVRKNSKNIKIVPRILFDGWTYHDFESVFGSEDEIEELSQSMVLLAKNENFDGFVVEVWSQLGNQKQKELIHLLIHLSEALHEAQLKLILVIPPAVAAGTNQPGMFTKKEFDQLASAVDSFSLMTYDYSTPQRPGPNSPLPWVRACIQVLDPDSKWRNKILLGLNFYGMDYSALGALGEPILGTRYIETLKEHKPKIVWDEQIAEHYFEYKKNKGGKHAIFYPTLKM", "length": 362, "header": "tr|A0A8V0ZZ35-1|A0A8V0ZRT1_CHICK Computationally mapped isoform of Chitinase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CHID1 PE=1 SV=1 CANONICAL=A0A8V0ZRT1-1" }, "locus": { "chromosome": "5", "start_pos": 14848998, "end_pos": 14748658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059244.1", "url": "https://www.ensembl.org/id/ENSGALT00010059244.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036164.1", "url": "https://www.ensembl.org/id/ENSGALP00010036164.1" } ] } }, { "isoform_ac": "A0A8V1A4F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1/entry#A0A8V1A4F2-1", "sequence": { "sequence": "MRFLCISVCLTMICWLAEGTLSKTDAKKAATKKLEEKTLHSDKNVQDRGLVVTDPKAKDIILEHRSYCSKKTKERHFSGDVLGYITPWNSHGYDIAKIFGNKFTLISPVWLQVRRRGKERFQFTGLHDVDKGWMKDVRKNSKNIKIVPRILFDGWTYHDFESVFGSEDEIEELSQSMVLLAKNENFDGFVVEVWSQLGNQKQKELIHLLIHLSEALHEAQLKLILVIPPAVAAGTNQPGMFTKKEFDQLASAVDSFSLMTYDYSTPQRPGPNSPLPWVRACIQVLDPDSKWRNKILLGLNFYGMDYSALGALGEPILGTRYIETLKEHKPKIVWDEQIAEHYFEYKKNKGGKHAIFYPTLKVGVTFAGPG", "length": 370, "header": "tr|A0A8V1A4F2-1|A0A8V0ZRT1_CHICK Computationally mapped isoform of Chitinase domain-containing protein 1 OS=Gallus gallus OX=9031 GN=CHID1 PE=1 SV=1 CANONICAL=A0A8V0ZRT1-1" }, "locus": { "chromosome": "5", "start_pos": 14846910, "end_pos": 14748658, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059235.1", "url": "https://www.ensembl.org/id/ENSGALT00010059235.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036156.1", "url": "https://www.ensembl.org/id/ENSGALP00010036156.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423103", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423103", "resource": "KEGG Pathway" }, { "id": "R-GGA-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RZ01-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "CHID1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRSLLGALWLALACGSAHGTLSKSDAKKAASKTLPEKTQVAGVPVQERGLVVTDLRAEDVVLEHRSYCSAKALRKHFAGDVLGYVTPWNSHGYDIAKIFAGKFTHVAPVWLQLRRHGREMFEVTGLDDVDQGWMRAVRKQTKGLRIVPRLRFEDWTYEDFRNVLDSEDEIEELSRTVVQVAKSQRFDGFVVEVWNQLLIQKHVGLIHMLTHVVEALHQARLLAILVIPPAVAPGTNKLGVFTHKEFEQLAPLLDGFSLMTYDYSTAQQPGPNAPLSWVRACVQVLDPKSRWRSKILLGLNFYGMDYAASKDAREPIIGARYIQTLKDHRPRITWDSQAAEHVFEYKKNRGGRHIVFYPTLKSLQVRLELARELGVGLSIWELGQGLDYFYDLL", "length": 393 }, "evidence": [ { "id": "A0A8V0ZRT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54G42-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "chid1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKQLILCLFLLSLLMISTFVTNADDNDNEIYEEEEDFTTNRDVKQRGLVRENVSAKQIINNYNKYFKNVDIKNFEQGNTLVYITPWNGKGYDVATKWAKKFTHISPVWHQVKFENNKVMIEGDHNIDKKWMEKVKENSDQKSKILPRFSFEGQQWGSKESFQKYIDPKLIDSLVSTVKKNNYDGLVIEGIVHINKQLRDPFLISLSEKLHSIGKEIILVIYPFRQKGQETGFGAKDFELLSNHIDGVSLMTYDFGPSGGMNAPKVWVEDNLKFLLPNGENKNSKKIFMGIPFYGYKIGENDQSDAIVGSEFISVLKQNKSKKLKFDQNTHEHIFTYKNKKNQQVSMTYPSLLFIEDRIQLANKYKVSISIWEIGQGLDYFMDLL", "length": 385 }, "evidence": [ { "id": "A0A8V0ZRT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT1/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5EAB4-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "CHID1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRVLLGTLWLTLACSSVHATLSKSDAKKAASKTLQEKTQVSGKPAQERGLVVTDLRAEDVVLEHRSYCSAKAHRKHFAGDVLGYITPWNRHGYDVAKIFGGKFTHVAPVWLQLRRHGREMFEVTGLDDVDQGWLRAVRKQAKGLRIVPRLRFEDWTYEDFDSVLDNEDEIEELSRTVVQVAKSQHFDGLVVEVWNQLLVQKHAGLIHLLTHMAEALHQARLLVFLVIPPAVAPGTNKLGMFTNTEFEQLAPVLDGFSLMTYDYSTAQPAGPNAPLPWVRACVQVLDPKSKWRSKILLGLNFYGMDYSASKDAREPIIGARYIQTLKDHRPQVVWDSQAAEHFFEYKKSRGGRHVVFYPTLKSLQERLELAQELGVGLSIWELGQGLDYFYDLL", "length": 393 }, "evidence": [ { "id": "A0A8V0ZRT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q922Q9-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "Chid1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWPLLHVLWLALVCGSVHTTLSKSDAKKAASKMLLEKTQFSDKPVQDRGLVVTDIKAEDVVLEHRSYCSSRARERNFAGEVLGYVTPWNSHGYDVAKVFGSKFTQISPVWLQLKRRGREMFEITGLHDVDQGWMRAVKKHAKGVRIVPRLLFEDWTYDDFRNVLDSEDEIEELSKTVAQVAKNQHFDGFVVEVWSQLLSQKHVGLIHMLTHLAEALHQARLLVILVIPPAVTPGTDQLGMFTHKEFEQLAPILDGFSLMTYDYSTSQQPGPNAPLSWIRACVQVLDPKSQWRSKILLGLNFYGMDYAASKDAREPVIGARYVQTLKDHRPRVVWDSQAAEHFFEYKKNRGGRHVVFYPTLKSLQVRLELARELGVGVSIWELGQGLDYFYDLL", "length": 393 }, "evidence": [ { "id": "A0A8V0ZRT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWS9-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "CHID1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTLFNLLWLALACSPVHTTLSKSDAKKAASKTLLEKSQFSDKPVQDRGLVVTDLKAESVVLEHRSYCSAKARDRHFAGDVLGYVTPWNSHGYDVTKVFGSKFTQISPVWLQLKRRGREMFEVTGLHDVDQGWMRAVRKHAKGLHIVPRLLFEDWTYDDFRNVLDSEDEIEELSKTVVQVAKNQHFDGFVVEVWNQLLSQKRVGLIHMLTHLAEALHQARLLALLVIPPAITPGTDQLGMFTHKEFEQLAPVLDGFSLMTYDYSTAHQPGPNAPLSWVRACVQVLDPKSKWRSKILLGLNFYGMDYATSKDAREPVVGARYIQTLKDHRPRMVWDSQASEHFFEYKKSRSGRHVVFYPTLKSLQVRLELARELGVGVSIWELGQGLDYFYDLL", "length": 393 }, "evidence": [ { "id": "A0A8V0ZRT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9M159-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "F2N1.39-01", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MARRRRSSAAESLKRRNDGYESLCQVVQQDSDRRLITIFVIFFIVIPAVSIAVYKVKFADRVIQTESSIRQKGIVKTDINFQEILTEHSKASENSTRHYDYPVLAYITPWNSKGYDMAKIFNSKFTHLSPVWYDLKSQGSGLVLEGRHNADKGWIQELRSRGNALILPRVVLEAIPGEMLNKKKLREKAISLIVTECKEMEYNGIVLESWSRWAAYGVLHDPDLRKMALKFVKQLGDALHSTSSPRNNQQHMQFMYVVGPPRSEKLQMYDFGPEDLQFLKDSVDGFSLMTYDFSNPQNPGPNAPVKWIDLTLKLLLGSSNNIDSNIARKVLLGINFYGNDFVISGDSGGGGAITGRDYLALLQKHKPTFRWDKESGEHLFMYRDDKNIKHAVFYPTLMSILLRLENARLWGIGISIWEIGQGLDYFFDLL", "length": 430 }, "evidence": [ { "id": "A0A8V0ZRT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VLS0-1", "protein_name": "Chitinase domain-containing protein 1", "gene_name": "Dmel\\CG8460", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRAPDALLLRVALLLLLLTTVRGTLAPDSHKSKSKTKESALRGGPQDQDVFDLGLVSPEPLAKDIVSNHRGYFKETGLRRFNGTTLGYVTPWNSHGYDVAKIFAKKFDIISPVWLQIVKQGDRYAVAGTHDIDAGWLTDVRRKGKQVHNQRTVKVFPRFIFDHFTDRDIKLLLSDAQERTKVNDVLIKCCKDNGFDGLVLEVWSQLAGRIDDKILYTLVLQMAKELQKQQLRLILVIPPFRKETGHLFGEKHMDKLFKHIYAFSLMTYDFSSVQRPGANAPLYFVRKAVETIAPEGCADMTAKRAKILLGLNMYGNDYTPDGGGPITFSQYLDLVRHVKKHLTYDERDVENFFEIKNDDGRHIVFYPTLYSINERIKLAQELGTGISIWELGQGLNYFYDLF", "length": 402 }, "evidence": [ { "id": "A0A8V0ZRT1", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "oligosaccharide binding", "id": "GO:0070492", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070492", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ], "pmid": "" }, { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ], "pmid": "" }, { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ], "pmid": "" }, { "name": "negative regulation of cytokine production involved in inflammatory response", "id": "GO:1900016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900016", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT1" }, { "id": "PS51910", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51910" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GH18", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 393, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3S5-1", "uniprot_ac": "A0A8V0Z3S5", "uniprot_id": "A0A8V0Z3S5_CHICK", "mass": { "chemical_mass": 41354.0, "monoisotopic_mass": 41354.0 }, "refseq": {}, "gene_names": [ { "name": "SLC25A47", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 47", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC25A47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5", "locus": { "chromosome": "5", "start_pos": 48073184, "end_pos": 48042504, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016619", "url": "https://www.ensembl.org/id/ENSGALG00010016619" } ] } } ], "crossref": [ { "id": "A0A8V0Z3S5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3S5", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQD6", "url": "https://www.orthodb.org/?gene=A0A8V0YQD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWR8", "url": "https://www.orthodb.org/?gene=A0A8V0YWR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWS7", "url": "https://www.orthodb.org/?gene=A0A8V0YWS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX72", "url": "https://www.orthodb.org/?gene=A0A8V0YX72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYN6", "url": "https://www.orthodb.org/?gene=A0A8V0YYN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYP5", "url": "https://www.orthodb.org/?gene=A0A8V0YYP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3R5", "url": "https://www.orthodb.org/?gene=A0A8V0Z3R5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3S5", "url": "https://www.orthodb.org/?gene=A0A8V0Z3S5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YQD6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWR8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWS7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYN6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3R5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVGIQQPIVLMRRSGVERLSDSPTAIEKNLHHFLNYCSHHLPFLWEQLHIFLVLRAPDPDAVHPMETCKGRVEGDNHLALPAGHCSVDAAQGGLSTAVGYPLDTVKVRIQTEGHYNGIWHCIQETYRTERVLGFYKGVSASVFTVSLISSVSFGTYRNFLCNICKLRYGTADAKPSGLDVSLAGGAAGAVRVVLMTPSEVAKVRMQTQRNPHPSVTSSQPLSKPKYRGSLHCLKVIAKEEGFGGLYKGCSALLCRDCSSSAIYFLTYSSLCDWLTPAGKNKPGFLVVLLSGGSAGVLAWGLATPLDVLKSRMQVDESGQHKYKGLIHCARESIRQEGLKVLFKGLGLNCIRAFPVNMVVFVTYEAVLRFTDHFANKK", "length": 378, "header": "tr|A0A8V0Z3S5-1|A0A8V0Z3S5_CHICK Isoform 1 of Solute carrier family 25 member 47 OS=Gallus gallus OX=9031 GN=SLC25A47 PE=3 SV=1 CANONICAL=A0A8V0Z3S5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5/entry#A0A8V0YQD6-1", "sequence": { "sequence": "MDFIAGAIGGKEIKRCFLLEAGGLSTAVGYPLDTVKVRIQTEGHYNGIWHCIQETYRTERVLGFYKGVSASVFTVSLISSVSFGTYRNFLCNICKLRYGTADAKPSGLDVSLAGGAAGAVRVVLMTPSEVAKVRMQTQRNPHPSVTSSQPLSKPKYRGSLHCLKVIAKEEGFGGLYKGCSALLCRDCSSSAIYFLTYSSLCDWLTPAGKNKPGFLVVLLSGGSAGVLAWGLATPLDVLKSRMQVDESGQHKYKGLIHCARESIRQEGLKVLFKGLGLNCIRAFPVNMVVFVTYEAVLRFTDHFANKK", "length": 307, "header": "tr|A0A8V0YQD6-1|A0A8V0Z3S5_CHICK Computationally mapped isoform of Solute carrier family 25 member 47 OS=Gallus gallus OX=9031 GN=SLC25A47 PE=3 SV=1 CANONICAL=A0A8V0Z3S5-1" }, "locus": { "chromosome": "5", "start_pos": 48069884, "end_pos": 48061775, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040079.1", "url": "https://www.ensembl.org/id/ENSGALT00010040079.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023228.1", "url": "https://www.ensembl.org/id/ENSGALP00010023228.1" } ] } }, { "isoform_ac": "A0A8V0YWR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5/entry#A0A8V0YWR8-1", "sequence": { "sequence": "MDFIAGAIGVGENQRSIAVCLSEIQSSGLSTAVGYPLDTVKVRIQTEGHYNGIWHCIQETYRTERVLGFYKGVSASVFTVSLISSVSFGTYRNFLCNICKLRYGTADAKPSGLDVSLAGGAAGAVRVVLMTPSEVAKVRMQTQRNPHPSVTSSQPLSKPKYRGSLHCLKVIAKEEGFGGLYKGCSALLCRDCSSSAIYFLTYSSLCDWLTPAGKNKPGFLVVLLSGGSAGVLAWGLATPLDVLKSRMQVDESGQHKYKGLIHCARESIRQEGLKVLFKGLGLNCIRAFPVNMVVFVTYEAVLRFTDHFANKK", "length": 312, "header": "tr|A0A8V0YWR8-1|A0A8V0Z3S5_CHICK Computationally mapped isoform of Solute carrier family 25 member 47 OS=Gallus gallus OX=9031 GN=SLC25A47 PE=3 SV=1 CANONICAL=A0A8V0Z3S5-1" }, "locus": { "chromosome": "5", "start_pos": 48069884, "end_pos": 48061775, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040076.1", "url": "https://www.ensembl.org/id/ENSGALT00010040076.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023225.1", "url": "https://www.ensembl.org/id/ENSGALP00010023225.1" } ] } }, { "isoform_ac": "A0A8V0YWS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5/entry#A0A8V0YWS7-1", "sequence": { "sequence": "MRCMTCGCSGGGGFTADTGGQGWKGCSPWFSLAAGFVLPLMAPRGDLREGGLSTAVGYPLDTVKVRIQTEGHYNGIWHCIQETYRTERVLGFYKGVSASVFTVSLISSVSFGTYRNFLCNICKLRYGTADAKPSGLDVSLAGGAAGAVRVVLMTPSEVAKVRMQTQRNPHPSVTSSQPLSKPKYRGSLHCLKVIAKEEGFGGLYKGCSALLCRDCSSSAIYFLTYSSLCDWLTPAGKNKPGFLVVLLSGGSAGVLAWGLATPLDVLKSRMQVDESGQHKYKGLIHCARESIRQEGLKVLFKGLGLNCIRAFPVNMVVFVTYEAVLRFTDHFANKK", "length": 335, "header": "tr|A0A8V0YWS7-1|A0A8V0Z3S5_CHICK Computationally mapped isoform of Solute carrier family 25 member 47 OS=Gallus gallus OX=9031 GN=SLC25A47 PE=3 SV=1 CANONICAL=A0A8V0Z3S5-1" }, "locus": { "chromosome": "5", "start_pos": 48069884, "end_pos": 48055306, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040087.1", "url": "https://www.ensembl.org/id/ENSGALT00010040087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023235.1", "url": "https://www.ensembl.org/id/ENSGALP00010023235.1" } ] } }, { "isoform_ac": "A0A8V0YX72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5/entry#A0A8V0YX72-1", "sequence": { "sequence": "MTCGCSGGGGFTADTGGQGWKGCSPWFSLAAGFVLPLMAPRGDLREGGLSTAVGYPLDTVKVRIQTEGHYNGIWHCIQETYRTERVLGFYKGVSASVFTVSLISSVSFGTYRNFLCNICKLRYGTADAKPSGLDVSLAGGAAGAVRVVLMTPSEVAKVRMQTQRNPHPSVTSSQPLSKPKYRGSLHCLKVIAKEEGFGGLYKGCSALLCRDCSSSAIYFLTYSSLCDWLTPAGKNKPGFLVVLLSGGSAGVLAWGLATPLDVLKSRMQVDESGQHKYKGLIHCARESIRQEGLKVLFKGLGLNCIRAFPVNMVVFVTYEAVLRFTDHFANKK", "length": 332, "header": "tr|A0A8V0YX72-1|A0A8V0Z3S5_CHICK Computationally mapped isoform of Solute carrier family 25 member 47 OS=Gallus gallus OX=9031 GN=SLC25A47 PE=3 SV=1 CANONICAL=A0A8V0Z3S5-1" }, "locus": { "chromosome": "5", "start_pos": 48069884, "end_pos": 48055430, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040091.1", "url": "https://www.ensembl.org/id/ENSGALT00010040091.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023237.1", "url": "https://www.ensembl.org/id/ENSGALP00010023237.1" } ] } }, { "isoform_ac": "A0A8V0YYN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5/entry#A0A8V0YYN6-1", "sequence": { "sequence": "MLSVLNVPHGLSLLELKQFFCSPKEAANPAEGCQTTQELHIFLVLRAPDPDAVHPMETCKGRVEGDNHLALPAGHCSVDAAQGGLSTAVGYPLDTVKVRIQTEGHYNGIWHCIQETYRTERVLGFYKGVSASVFTVSLISSVSFGTYRNFLCNICKLRYGTADAKPSGLDVSLAGGAAGAVRVVLMTPSEVAKVRMQTQRNPHPSVTSSQPLSKPKYRGSLHCLKVIAKEEGFGGLYKGCSALLCRDCSSSAIYFLTYSSLCDWLTPAGKNKPGFLVVLLSGGSAGVLAWGLATPLDVLKSRMQVDESGQHKYKGLIHCARESIRQEGLKVLFKGLGLNCIRAFPVNMVVFVTYEAVLRFTDHFANKK", "length": 368, "header": "tr|A0A8V0YYN6-1|A0A8V0Z3S5_CHICK Computationally mapped isoform of Solute carrier family 25 member 47 OS=Gallus gallus OX=9031 GN=SLC25A47 PE=3 SV=1 CANONICAL=A0A8V0Z3S5-1" }, "locus": { "chromosome": "5", "start_pos": 48069884, "end_pos": 48063057, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040072.1", "url": "https://www.ensembl.org/id/ENSGALT00010040072.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023221.1", "url": "https://www.ensembl.org/id/ENSGALP00010023221.1" } ] } }, { "isoform_ac": "A0A8V0YYP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5/entry#A0A8V0YYP5-1", "sequence": { "sequence": "MRKLPCDLKRKLPMCLHLLLDARIDNEQLHIFLVLRAPDPDAVHPMETCKGRVEGDNHLALPAGHCSVDAAQGGLSTAVGYPLDTVKVRIQTEGHYNGIWHCIQETYRTERVLGFYKGVSASVFTVSLISSVSFGTYRNFLCNICKLRYGTADAKPSGLDVSLAGGAAGAVRVVLMTPSEVAKVRMQTQRNPHPSVTSSQPLSKPKYRGSLHCLKVIAKEEGFGGLYKGCSALLCRDCSSSAIYFLTYSSLCDWLTPAGKNKPGFLVVLLSGGSAGVLAWGLATPLDVLKSRMQVDESGQHKYKGLIHCARESIRQEGLKVLFKGLGLNCIRAFPVNMVVFVTYEAVLRFTDHFANKK", "length": 358, "header": "tr|A0A8V0YYP5-1|A0A8V0Z3S5_CHICK Computationally mapped isoform of Solute carrier family 25 member 47 OS=Gallus gallus OX=9031 GN=SLC25A47 PE=3 SV=1 CANONICAL=A0A8V0Z3S5-1" }, "locus": { "chromosome": "5", "start_pos": 48069884, "end_pos": 48061118, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040082.1", "url": "https://www.ensembl.org/id/ENSGALT00010040082.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023231.1", "url": "https://www.ensembl.org/id/ENSGALP00010023231.1" } ] } }, { "isoform_ac": "A0A8V0Z3R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5/entry#A0A8V0Z3R5-1", "sequence": { "sequence": "MLLSKLRGGTETIQFGAFHLALFNRAAWIPGLVHACGLSTAVGYPLDTVKVRIQTEGHYNGIWHCIQETYRTERVLGFYKGVSASVFTVSLISSVSFGTYRNFLCNICKLRYGTADAKPSGLDVSLAGGAAGAVRVVLMTPSEVAKVRMQTQRNPHPSVTSSQPLSKPKYRGSLHCLKVIAKEEGFGGLYKGCSALLCRDCSSSAIYFLTYSSLCDWLTPAGKNKPGFLVVLLSGGSAGVLAWGLATPLDVLKSRMQVDESGQHKYKGLIHCARESIRQEGLKVLFKGLGLNCIRAFPVNMVVFVTYEAVLRFTDHFANKK", "length": 321, "header": "tr|A0A8V0Z3R5-1|A0A8V0Z3R5_CHICK Computationally mapped isoform of Solute carrier family 25 member 47 OS=Gallus gallus OX=9031 GN=SLC25A47 PE=3 SV=1 CANONICAL=A0A8V0Z3S5-1" }, "locus": { "chromosome": "5", "start_pos": 48069884, "end_pos": 48066220, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040070.1", "url": "https://www.ensembl.org/id/ENSGALT00010040070.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023219.1", "url": "https://www.ensembl.org/id/ENSGALP00010023219.1" } ] } }, { "isoform_ac": "A0A8V0Z3S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5/entry#A0A8V0Z3S5-1", "sequence": { "sequence": "MAVGIQQPIVLMRRSGVERLSDSPTAIEKNLHHFLNYCSHHLPFLWEQLHIFLVLRAPDPDAVHPMETCKGRVEGDNHLALPAGHCSVDAAQGGLSTAVGYPLDTVKVRIQTEGHYNGIWHCIQETYRTERVLGFYKGVSASVFTVSLISSVSFGTYRNFLCNICKLRYGTADAKPSGLDVSLAGGAAGAVRVVLMTPSEVAKVRMQTQRNPHPSVTSSQPLSKPKYRGSLHCLKVIAKEEGFGGLYKGCSALLCRDCSSSAIYFLTYSSLCDWLTPAGKNKPGFLVVLLSGGSAGVLAWGLATPLDVLKSRMQVDESGQHKYKGLIHCARESIRQEGLKVLFKGLGLNCIRAFPVNMVVFVTYEAVLRFTDHFANKK", "length": 378, "header": "tr|A0A8V0Z3S5-1|A0A8V0Z3S5_CHICK Isoform 1 of Solute carrier family 25 member 47 OS=Gallus gallus OX=9031 GN=SLC25A47 PE=3 SV=1 CANONICAL=A0A8V0Z3S5-1" }, "locus": { "chromosome": "5", "start_pos": 48069884, "end_pos": 48058401, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040080.1", "url": "https://www.ensembl.org/id/ENSGALT00010040080.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023229.1", "url": "https://www.ensembl.org/id/ENSGALP00010023229.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5" } ], "pmid": "" }, { "name": "acetyl-CoA transmembrane transporter activity", "id": "GO:0008521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008521", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5" } ], "pmid": "" }, { "name": "NAD transmembrane transporter activity", "id": "GO:0051724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051724", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3S5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3S5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z414-1", "uniprot_ac": "A0A8V0Z414", "uniprot_id": "A0A8V0Z414_CHICK", "mass": { "chemical_mass": 64707.0, "monoisotopic_mass": 64707.0 }, "refseq": {}, "gene_names": [ { "name": "NOX1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z414", "database": "UniProtKB", "url": 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], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "63180", "name": "", "equation": "NADPH + 2 O2 = 2 superoxide + NADP(+) + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XXD6-1" ], "evidence": [ { "id": "63180", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/63180" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0XXD6", "gene_name": "NOX4", "activity": [ { "ec_number": "1.6.3.1", "activity": "NADH + O2 + H(+) = H2O2 + NAD(+).", "evidence": [ { "id": "A0A8V0XXD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXD6" } ] }, { "ec_number": "1.6.3.1", "activity": "", "evidence": [ { "id": "A0A8V0XXD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXD6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z414", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z414" }, { "id": "PS51384", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51384" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAD-binding FR-type", "eco_id": "ECO_0000259", "start_pos": 290, "end_pos": 391, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z460-1", "uniprot_ac": "A0A8V0Z460", "uniprot_id": "A0A8V0Z460_CHICK", "mass": { "chemical_mass": 58273.0, "monoisotopic_mass": 58273.0 }, "refseq": { "ac": "XP_025006672", "name": "WD repeat-containing protein 25 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006672" }, "gene_names": [ { "name": "WDR25", "type": "recommended", "evidence": [ { "id": "A0A8V0Z460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z460" } ] }, { "name": "WDR25", "type": "synonym", "evidence": [ { "id": "XP_025006672", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006672" } ] } ], "protein_names": [ { "name": "WD repeat domain 25", "type": "synonym", "evidence": [ { "id": "A0A8V0Z460", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z460/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 25 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025006672", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006672" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025006672.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025006672", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006672" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z460", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z460" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "WDR25", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z460", "locus": { "chromosome": "5", "start_pos": 48180727, "end_pos": 48092347, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016702", "url": "https://www.ensembl.org/id/ENSGALG00010016702" } ] } } ], "crossref": [ { "id": "A0A8V0Z460", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z460", "database": "AlphaFoldDB", "categories": [] }, { "id": "428908", "url": "https://www.ncbi.nlm.nih.gov/gene/428908", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428908", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428908", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDYETTA", "url": "https://omabrowser.org/oma/group/WDYETTA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YQR4", "url": "https://www.orthodb.org/?gene=A0A8V0YQR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX38", "url": "https://www.orthodb.org/?gene=A0A8V0YX38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXJ5", "url": "https://www.orthodb.org/?gene=A0A8V0YXJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z455", "url": "https://www.orthodb.org/?gene=A0A8V0Z455", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z460", "url": "https://www.orthodb.org/?gene=A0A8V0Z460", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44566", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44566", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44566:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44566:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025006672", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025006672", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YQR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YQR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX38", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z455", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z455", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z455-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z455-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z460", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z460", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z460-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z460-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSLVAYDDSEPEAETEKADNLGTSRQASLPSSSANPVQHFAPGILSTKSTYETQLTENTDNFGMSVVCEDPSEHYAGNNNSDLTSYCRRAYSSPTALRVPYKNYEQTLSSSKNSGNGASQKRTHKDSSTAPKGIRPYIPKRLRQENTSTCERKESDQSESASCDVKLDIPAEQTVRKISELIKPYLGSRYKLTEVPKSLIFHMSKHNGPVNAIQWCTVREQSHMLLSASMDKTIKVIQRSPLEVPLETSFLVWDAVDTGVCLRTFSCHSSAVRAAQWSSCGRRILSGGFDSMLHLTDVETGKQIISSENEFRISTLKFHPTDSNVFLCGGFSPEVKAWDIRICKVTRVYKAAVQQILDILFLPEGKEFLTSTDAVSRDSADRTIIAWDFLSAAKISNQIFHERYTCPSLALHPRESMFVAQTNGNYVALFSSQRPYRINKKKRYEGHKVEGFAVGCEFSPDGTLLVTGSSDGKVFFYNYHTSRIVRTLSAHREACVSAVFHPVLPSLLATSDWAGEIKIWQ", "length": 523, "header": "tr|A0A8V0Z460-1|A0A8V0Z460_CHICK Isoform 1 of WD repeat domain 25 OS=Gallus gallus OX=9031 GN=WDR25 PE=4 SV=1 CANONICAL=A0A8V0Z460-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YQR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z460/entry#A0A8V0YQR4-1", "sequence": { "sequence": "MLHLTDVETGKQIISSENEFRISTLKFHPTDSNVFLCGGFSPEVKAWDIRICKVTRVYKAAVQQILDILFLPEGKEFLTSTDAVSRDSADRTIIAWDFLSAAKISNQIFHERYTCPSLALHPRESMFVAQTNGNYVALFSSQRPYRINKKKRYEGHKVEGFAVGCEFSPDGTLLVTGSSDGKVFFYNYHTSRIVRTLSAHREACVSAVFHPVLPSLLATSDWAGEIKIWQ", "length": 230, "header": "tr|A0A8V0YQR4-1|A0A8V0Z460_CHICK Computationally mapped isoform of WD repeat domain 25 OS=Gallus gallus OX=9031 GN=WDR25 PE=4 SV=1 CANONICAL=A0A8V0Z460-1" }, "locus": { "chromosome": "5", "start_pos": 48150729, "end_pos": 48125624, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040271.1", "url": "https://www.ensembl.org/id/ENSGALT00010040271.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023351.1", "url": "https://www.ensembl.org/id/ENSGALP00010023351.1" } ] } }, { "isoform_ac": "A0A8V0YX38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z460/entry#A0A8V0YX38-1", "sequence": { "sequence": "FQSCVFKKQRSPRHLKCSNTNRFAFNNLGKQIISSENEFRISTLKFHPTDSNVFLCGGFSPEVKAWDIRICKVTRVYKAAVQQILDILFLPEGKEFLTSTDAVSRDSADRTIIAWDFLSAAKISNQIFHERYTCPSLALHPRESMFVAQTNGNYVALFSSQRPYRINKKKRYEGHKVEGFAVGCEFSPDGTLLVTGSSDGKVFFYNYHTSRIVRTLSAHREACVSAVFHPVLPSLLATSDWAGEIKIWQ", "length": 249, "header": "tr|A0A8V0YX38-1|A0A8V0Z460_CHICK Computationally mapped isoform of WD repeat domain 25 OS=Gallus gallus OX=9031 GN=WDR25 PE=4 SV=1 CANONICAL=A0A8V0Z460-1" }, "locus": { "chromosome": "5", "start_pos": 48150729, "end_pos": 48134361, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040261.1", "url": "https://www.ensembl.org/id/ENSGALT00010040261.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023343.1", "url": "https://www.ensembl.org/id/ENSGALP00010023343.1" } ] } }, { "isoform_ac": "A0A8V0YXJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z460/entry#A0A8V0YXJ5-1", "sequence": { "sequence": "MSSSLVAYDDSEPEAETEKADNLGTSRQASLPSSSANPVQHFAPGILSTKSTYETQLTENTDNFGMSVVCEDPSEHYAGNNNSDLTSYCRRAYSSPTALRVPYKNYEQTLSSSKNSGNGASQKRTHKDSSTAPKGIRPYIPKRLRQENTSTCERKESDQSESASCDVKLDIPAEQTVRKISELIKPYLGSRYKLTEVPKSLIFHMSKHNGPVNAIQWCTVREQSHMLLSASMDKTIKVWDAVDTGVCLRTFSCHSSAVRAAQWSSCGRRILSGGFDSMLHLTDVETGKQIISSENEFRISTLKFHPTDSNVFLCGGFSPEVKAWDIRICKVTRVYKAAVQQILDILFLPEGKEFLTSTDAVSRDSADRTIIAWDFLSAAKISNQIFHERYTCPSLALHPRESMFVAQTNGNYVALFSSQRPYRINKKKRYEGHKVEGFAVGCEFSPDGTLLVTGSSDGLFMEGFHELRCQLQNTCRVPALFNEMQDDNHKIYSLFNFTQRKGKCEPQLGKT", "length": 511, "header": "tr|A0A8V0YXJ5-1|A0A8V0Z460_CHICK Computationally mapped isoform of WD repeat domain 25 OS=Gallus gallus OX=9031 GN=WDR25 PE=4 SV=1 CANONICAL=A0A8V0Z460-1" }, "locus": { "chromosome": "5", "start_pos": 48179872, "end_pos": 48095600, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040275.1", "url": "https://www.ensembl.org/id/ENSGALT00010040275.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023355.1", "url": "https://www.ensembl.org/id/ENSGALP00010023355.1" } ] } }, { "isoform_ac": "A0A8V0Z455-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z460/entry#A0A8V0Z455-1", "sequence": { "sequence": "MKAQSSLHRNINHSRAVVHFGKQIISSENEFRISTLKFHPTDSNVFLCGGFSPEVKAWDIRICKVTRVYKAAVQQILDILFLPEGKEFLTSTDAVSRDSADRTIIAWDFLSAAKISNQIFHERYTCPSLALHPRESMFVAQTNGNYVALFSSQRPYRINKKKRYEGHKVEGFAVGCEFSPDGTLLVTGSSDGKVFFYNYHTSRIVRTLSAHREACVSAVFHPVLPSLLATSDWAGEIKIWQ", "length": 241, "header": "tr|A0A8V0Z455-1|A0A8V0Z455_CHICK Computationally mapped isoform of WD repeat domain 25 OS=Gallus gallus OX=9031 GN=WDR25 PE=4 SV=1 CANONICAL=A0A8V0Z460-1" }, "locus": { "chromosome": "5", "start_pos": 48150729, "end_pos": 48134051, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040266.1", "url": "https://www.ensembl.org/id/ENSGALT00010040266.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023347.1", "url": "https://www.ensembl.org/id/ENSGALP00010023347.1" } ] } }, { "isoform_ac": "A0A8V0Z460-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z460/entry#A0A8V0Z460-1", "sequence": { "sequence": "MSSSLVAYDDSEPEAETEKADNLGTSRQASLPSSSANPVQHFAPGILSTKSTYETQLTENTDNFGMSVVCEDPSEHYAGNNNSDLTSYCRRAYSSPTALRVPYKNYEQTLSSSKNSGNGASQKRTHKDSSTAPKGIRPYIPKRLRQENTSTCERKESDQSESASCDVKLDIPAEQTVRKISELIKPYLGSRYKLTEVPKSLIFHMSKHNGPVNAIQWCTVREQSHMLLSASMDKTIKVIQRSPLEVPLETSFLVWDAVDTGVCLRTFSCHSSAVRAAQWSSCGRRILSGGFDSMLHLTDVETGKQIISSENEFRISTLKFHPTDSNVFLCGGFSPEVKAWDIRICKVTRVYKAAVQQILDILFLPEGKEFLTSTDAVSRDSADRTIIAWDFLSAAKISNQIFHERYTCPSLALHPRESMFVAQTNGNYVALFSSQRPYRINKKKRYEGHKVEGFAVGCEFSPDGTLLVTGSSDGKVFFYNYHTSRIVRTLSAHREACVSAVFHPVLPSLLATSDWAGEIKIWQ", "length": 523, "header": "tr|A0A8V0Z460-1|A0A8V0Z460_CHICK Isoform 1 of WD repeat domain 25 OS=Gallus gallus OX=9031 GN=WDR25 PE=4 SV=1 CANONICAL=A0A8V0Z460-1" }, "locus": { "chromosome": "5", "start_pos": 48150729, "end_pos": 48095600, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040272.1", "url": "https://www.ensembl.org/id/ENSGALT00010040272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023352.1", "url": "https://www.ensembl.org/id/ENSGALP00010023352.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428908", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428908", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F4K0D3-1", "protein_name": "Transducin/WD40 repeat-like superfamily protein", "gene_name": "MRB17.2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLICNSYANDSDDEPEPVTNERLTSKIAAAPSIPSKRPYPVPEERQYKPPRRPYPPHGSYSESQTSSSFSIPVPVPVPVPGRYVSKRERSLLASLSTIPTPDQSSDLSQKPYSSPTVLGSISDSDVPRHVLSSVRHRPKGSSLQTEMPSRMSISLTGHTKAVTAIDWSTSHVHLLASAGLDGAVYVWNVWSNDKKKVRAFLHHNAPVKDVKWSKQGLSLLSCGYDCTSRLFDVERGVETQSFKEDEVVGVVKFHPDNCNVFLSGGSKGSLRLWDIRANKFVHEYVRDLGPILDVEFIAGGKQFISSSDVSGRNISENAVIVWDISREVPLSNQVYVEAYTCPCIKRHPQDPVFIAQSHGNYTAIFSTNPPFKLNKYKRFEGHWVAGFPIKCNFSPDGETLASGSSDGSVYMYDYKSTALIKKLKAYEQPCVNVSYHPVLPNVVAACSWNGQVSVFE", "length": 457 }, "evidence": [ { "id": "A0A8V0Z460", "url": "https://omabrowser.org/oma/group/A0A8V0Z460/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4T3-1", "uniprot_ac": "A0A8V0Z4T3", "uniprot_id": "A0A8V0Z4T3_CHICK", "mass": { "chemical_mass": 65493.0, "monoisotopic_mass": 65493.0 }, "refseq": {}, "gene_names": [ { "name": "LRRC31", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4T3" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 31", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4T3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4T3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4T3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LRRC31", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4T3", "locus": { "chromosome": "9", "start_pos": 19632701, "end_pos": 19594247, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016812", "url": "https://www.ensembl.org/id/ENSGALG00010016812" } ] } } ], "crossref": [ { "id": "A0A8V0Z4T3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4T3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042419", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042419", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR24109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24109:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24109:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YRA7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YRA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4T3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4T3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNAEYAAEERCPMACPGDAQSCQNKSEEDIPKSSPFDFVIKQFQGKRSSSGKRKEQPSAIQKFFSGFDFGKSEGKERQETEETLKNNCRADDQSEKENLPVEDESSQLISEAESPSGEQRFNQFMQKLGKKPNSKNLDLNNCALSAADVTELASLLPFLPELEEISLSWNGCVGGTLKTLTAQLHHVNLLKVLRLNNCRLSAEDVTSLGEAFEIVPQLEELDLSWNSNIGGKLSLLTKKLRKGCKIKLLKITDCNLTAKDGESLAEILNVLPNLEVLDLSINKHIGCSMKVIAQDLKNVPGLKELNLHMCGLKQDSLQGLDAALQHLTALRKLDISCNKEIGGGFKDSTAHLASLKNLEVLDLHQCCVTEEDVAVLSQVIPLLSSLRELNLSWNKNIGVSSDPLLGRLRFLPKLKSVAISNCGLGEESFSALAEAALHLPELEILDLSWNKCVGGNLKLLLGALKLATEIQVLRLSSCNLVAEDLALLTLLAHDGHLARLRKLDLSYNNNISDEGWMVFCQGLAALKELSELDVSLRPSSCSACGTWFSELLAALTKLPALAELGMQRWVLSESQRKQLEGFNQDNKRNIRFDC", "length": 595, "header": "tr|A0A8V0Z4T3-1|A0A8V0Z4T3_CHICK Isoform 1 of Leucine rich repeat containing 31 OS=Gallus gallus OX=9031 GN=LRRC31 PE=4 SV=1 CANONICAL=A0A8V0Z4T3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YRA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4T3/entry#A0A8V0YRA7-1", "sequence": { "sequence": "MEKTGDAQSCQNKSEEDIPKSSPFDFVIKQFQGKRSSSGKRKEQPSAIQKFFSGFDFGKSEGKERQETEETLKNNCRADDQSEKENLPVEDESSQLISEAESPSGEQRFNQFMQKLGKKPNSKNLDLNNCALSAADVTELASLLPFLPELEEISLSWNGCVGGTLKTLTAQLHHVNLLKVLRLNNCRLSAEDVTSLGEAFEIVPQLEELDLSWNSNIGGKLSLLTKKLRKGCKIKLLKITDCNLTAKDGESLAEILNVLPNLEVLDLSINKHIGCSMKVIAQDLKNVPGLKELNLHMCGLKQDSLQGLDAALQHLTALRKLDISCNKEIGGGFKDSTAHLASLKNLEVLDLHQCCVTEEDVAVLSQVIPLLSSLRELNLSWNKNIGVSSDPLLGRLRFLPKLKSVAISNCGLGEESFSALAEAALHLPELEILDLSWNKCVGGNLKLLLGALKLATEIQVLRLSSCNLVAEDLALLSTYNMVFTSSRGASAHRPQFRRDLFHVLSTFLDKSNEKMENTALFFPEIIFILLKAGCPEHAQCKD", "length": 542, "header": "tr|A0A8V0YRA7-1|A0A8V0Z4T3_CHICK Computationally mapped isoform of Leucine rich repeat containing 31 OS=Gallus gallus OX=9031 GN=LRRC31 PE=4 SV=1 CANONICAL=A0A8V0Z4T3-1" }, "locus": { "chromosome": "9", "start_pos": 19630867, "end_pos": 19620883, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040577.1", "url": "https://www.ensembl.org/id/ENSGALT00010040577.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023559.1", "url": "https://www.ensembl.org/id/ENSGALP00010023559.1" } ] } }, { "isoform_ac": "A0A8V0Z4T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4T3/entry#A0A8V0Z4T3-1", "sequence": { "sequence": "MKNAEYAAEERCPMACPGDAQSCQNKSEEDIPKSSPFDFVIKQFQGKRSSSGKRKEQPSAIQKFFSGFDFGKSEGKERQETEETLKNNCRADDQSEKENLPVEDESSQLISEAESPSGEQRFNQFMQKLGKKPNSKNLDLNNCALSAADVTELASLLPFLPELEEISLSWNGCVGGTLKTLTAQLHHVNLLKVLRLNNCRLSAEDVTSLGEAFEIVPQLEELDLSWNSNIGGKLSLLTKKLRKGCKIKLLKITDCNLTAKDGESLAEILNVLPNLEVLDLSINKHIGCSMKVIAQDLKNVPGLKELNLHMCGLKQDSLQGLDAALQHLTALRKLDISCNKEIGGGFKDSTAHLASLKNLEVLDLHQCCVTEEDVAVLSQVIPLLSSLRELNLSWNKNIGVSSDPLLGRLRFLPKLKSVAISNCGLGEESFSALAEAALHLPELEILDLSWNKCVGGNLKLLLGALKLATEIQVLRLSSCNLVAEDLALLTLLAHDGHLARLRKLDLSYNNNISDEGWMVFCQGLAALKELSELDVSLRPSSCSACGTWFSELLAALTKLPALAELGMQRWVLSESQRKQLEGFNQDNKRNIRFDC", "length": 595, "header": "tr|A0A8V0Z4T3-1|A0A8V0Z4T3_CHICK Isoform 1 of Leucine rich repeat containing 31 OS=Gallus gallus OX=9031 GN=LRRC31 PE=4 SV=1 CANONICAL=A0A8V0Z4T3-1" }, "locus": { "chromosome": "9", "start_pos": 19632059, "end_pos": 19601226, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040569.1", "url": "https://www.ensembl.org/id/ENSGALT00010040569.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023555.1", "url": "https://www.ensembl.org/id/ENSGALP00010023555.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": 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"glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z2Z3-1", "uniprot_ac": "A0A8V0Z2Z3", "uniprot_id": "A0A8V0Z2Z3_CHICK", "mass": { "chemical_mass": 137124.0, "monoisotopic_mass": 137124.0 }, "refseq": { "ac": "XP_046759455", "name": "AP2-associated protein kinase 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759455" }, "gene_names": [ { "name": "AAK1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ] }, { "name": "AAK1", "type": "synonym", "evidence": [ { "id": "XP_046759455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759455" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z2Z3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3/entry#names_and_taxonomy" } ] }, { "name": "AP2-associated protein kinase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046759455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759455" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046759455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759455" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AAK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3", "locus": { "chromosome": "22", "start_pos": 148900, "end_pos": 82889, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017516", "url": "https://www.ensembl.org/id/ENSGALG00010017516" } ] } } ], "crossref": [ { "id": "A0A8V0Z2Z3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z2Z3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419512", "url": "https://www.ncbi.nlm.nih.gov/gene/419512", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419512", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419512", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VSQFPVM", "url": "https://omabrowser.org/oma/group/VSQFPVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUT7", "url": "https://www.orthodb.org/?gene=A0A8V0YUT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YUU2", "url": "https://www.orthodb.org/?gene=A0A8V0YUU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z182", "url": "https://www.orthodb.org/?gene=A0A8V0Z182", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z187", "url": "https://www.orthodb.org/?gene=A0A8V0Z187", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1M5", "url": "https://www.orthodb.org/?gene=A0A8V0Z1M5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1N6", "url": "https://www.orthodb.org/?gene=A0A8V0Z1N6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1Q3", "url": "https://www.orthodb.org/?gene=A0A8V0Z1Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2X6", "url": "https://www.orthodb.org/?gene=A0A8V0Z2X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2Z3", "url": "https://www.orthodb.org/?gene=A0A8V0Z2Z3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47907", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47907", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47907:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47907:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15282", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15282", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8856825", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-8856828", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_046759455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046759455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YUT7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z182", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z182", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z182-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z182-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z187", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z187", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z187-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z187-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1M5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1M5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1N6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1Q3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2X6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKFFDSRREQGGSGPGSGTSGGGGGSGGPGSGYIGRVFGIGRRQVTVDEVLAEGGFAIVFLVRTNNGMKCALKRMYVNNEYDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEEEIKKYTTLSYRAPEMVNLYSGKLITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRHSQDMHCLIRYMLEPDPDKRPDIYQVSYFAFKLAKKECPVQNVQNSPIPAKLPDPVKASEAAAKKSQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRPTAQAAIQPQGPAALGSGQPSLPASVPQQKAAPQPTSAQPQAKQVSAPQQASQAQPQVPSAQPQATPQHQQQLFLKQQLLQQQQQQQAAYYQQQQVMQAQQFPVMQQGAPAQQQLMQNYYQQQQQQQQMMAQQAAMQQKTAAAAVQQKQQATAPPQPQAQQSAAQPTPQQEQAMQAQIRQQQKPQTTPPTAVQGQKLGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSASTTPSGSPRTSQQNVYNPPDVSTWNPFDDDNFSKLTAEELLNKDFAKLGDGKAPEKMGSSTENLIPGFQPASSAAQADAFGGSSSFTAGSAEKMKDILSLDASPPLLTVPDPFIPLPLSDTPEKLIEGLKSPETALLLPDILPLADPFGSTSDAVNGKPDVAVESLIPGLEAPLPQCLVSQTESVASNRTDSLTGEDSLLDCSLLSNPAADLLDEFAPVAFTAQPHKEDTNLIAGFDAPEGSEKVTEDEFDPIPVLISKNSQGLQRDPALFPAVPLDLCKGPAASDGLALYKTQPEVKTQPNAEPDGAARDGPSSNSSFYSSEGEGTDHEGDILDCSGSRPLLLDSEEEEEGCRPGTGFLQAGPRERRDISREQHPHTQAVETPFPAFQSHSGEVFNEPDVFATAPFRSSRKAPDEADVFTKAPFISKGSAALRHPEEADVFLRAPFTKKKSMEELLSHSVPKEPLVFLSPAADIQHRTTPAFQSLDAVVSGPSARPQYPSAGFALLTNLPPSVRAAEEHSPPAGVQPEPGERSPAQAGPQECTLGPVTNSRPFRPQALSKYSRHYSPEDGPGLDVQPIAAYKVVSQTNRQAIAGSVSVAPLAARTTELPAADPFASAPFPSKAAKQKP", "length": 1274, "header": "tr|A0A8V0Z2Z3-1|A0A8V0Z2Z3_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=AAK1 PE=1 SV=1 CANONICAL=A0A8V0Z2Z3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YUT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3/entry#A0A8V0YUT7-1", "sequence": { "sequence": "MKKFFDSRREQGGSGPGSGTSGGGGGSGGPGSGYIGRVFGIGRRQVTVDEVLAEGGFAIVFLVRTNNGMKCALKRMYVNNEYDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEEEIKKYTTLSYRAPEMVNLYSGKLITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRHSQDMHCLIRYMLEPDPDKRPDIYQVSYFAFKLAKKECPVQNVQNSPIPAKLPDPVKASEAAAKKSQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRPTAQAAIQPQGPAALGSGQPSLPASVPQQKAAPQPTSAQPQAKQVSAPQQASQAQPQVPSAQPQATPQHQQQLFLKQQLLQQQQQQQAAYYQQQQVMQAQQFPVMQQGAPAQQQLMQNYYQQQQQQQQMMAQQAAMQQKTAAAAVQQKQQATAPPQPQAQQSAAQPTPQQEQAMQAQIRQQQKPQTTPPTAVQGQKLGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSASTTPSGSPRTSQQNVYNPPDVSTWNPFDDDNFSKLTAEELLNKDFAKLGDGKAPEKMGSSTENLIPGFQPASSAAQADAFGGSSSFTAGSAEKMKDILSLDASPPLLTVPDPFIPLPLSDTPGLQRDPALFPAVPLDLCKGPAASDGLALYKTQPEVKTQPNAEPDGAARDGPSSNSSFYSSEGEGTDHEGDILDCSGSRPLLLDSEEEEEGCRPGTGFLQAGPRERRDISREQHPHTQAVETPFPAFQSHSGEVFNEPDVFATAPFRSSRKAPDEADVFTKAPFISKGSAALRHPEEADVFLRAPFTKKKSMEELLSHSVPKEPLVFLSPAADIQHRTTPAFQSLDAVVSGPSARPQYPSAGFALLTNLPPSVRAAEEHSPPAGVQPEPGERSPAQAGPQECTLGPVTNSRPFRPQALSKYSRHYSPEDGPGLDVQPIAAYKVVSQTNRQAIAGSVSVAPLAARTTELPAADPFASAPFPSKAAKQKP", "length": 1134, "header": "tr|A0A8V0YUT7-1|A0A8V0Z2Z3_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=AAK1 PE=1 SV=1 CANONICAL=A0A8V0Z2Z3-1" }, "locus": { "chromosome": "22", "start_pos": 144993, "end_pos": 83131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042342.1", "url": "https://www.ensembl.org/id/ENSGALT00010042342.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024832.1", "url": "https://www.ensembl.org/id/ENSGALP00010024832.1" } ] } }, { "isoform_ac": "A0A8V0YUU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3/entry#A0A8V0YUU2-1", "sequence": { "sequence": "MKKFFDSRREQGGSGPGSGTSGGGGGSGGPGSGYIGRVFGIGRRQVTVDEVLAEGGFAIVFLVRTNNGMKCALKRMYVNNEYDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEEEIKKYTTLSYRAPEMVNLYSGKLITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRHSQDMHCLIRYMLEPDPDKRPDIYQVSYFAFKLAKKECPVQNVQNSPIPAKLPDPVKASEAAAKKSQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRPTAQAAIQPQGPAALGSGQPSLPASVPQQKAAPQPTSAQPQAKQVSAPQQASQAQPQVPSAQPQATPQHQQQLFLKQQLLQQQQQQQAAYYQQQQVMQAQQFPVMQQGAPAQQQLMQNYYQQQQQQQQMMAQQAAMQQKTAAAAVQQKQQATAPPQPQAQQSAAQPTPQQEQAMQAQIRQQQKPQTTPPTAVQGQKLGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSASTTPSGSPRTSQQNVYNPPDVSTWNPFDDDNFSKLTAEELLNKDFAKLGDGKAPEKMGSSTENLIPGFQPASSAAQADAFGGSSSFTAGSGLQRDPALFPAVPLDLCKGPAASDGLALYKTQPEVKTQPNAEPDGAARDGPSSNSSFYSSEGEGTDHEGDILDCSGSRPLLLDSEEEEEGCRPGTGFLQAGPRERRDISREQHPHTQAVETPFPAFQSHSGEVFNEPDVFATAPFRSSRKAPDEADVFTKAPFISKGSAALRHPEEADVFLRAPFTKKKSMEELLSHSVPKEPLVFLSPAADIQHRTTPAFQSLDAVVSGPSARPQYPSAGFALLTNLPPSVRAAEEHSPPAGVQPEPGERSPAQAGPQECTLGPVTNSRPFRPQALSKYSRHYSPEDGPGLDVQPIAAYKVVSQTNRQAIAGSVSVAPLAARTTELPAADPFASAPFPSKAAKQKP", "length": 1102, "header": "tr|A0A8V0YUU2-1|A0A8V0Z2Z3_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=AAK1 PE=1 SV=1 CANONICAL=A0A8V0Z2Z3-1" }, "locus": { "chromosome": "22", "start_pos": 144993, "end_pos": 83131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042347.1", "url": "https://www.ensembl.org/id/ENSGALT00010042347.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024837.1", "url": "https://www.ensembl.org/id/ENSGALP00010024837.1" } ] } }, { "isoform_ac": "A0A8V0Z182-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3/entry#A0A8V0Z182-1", "sequence": { "sequence": "FHLPSPSRFFHVWWWFKSEYHDIPRVLSTSHLSLRLRKCSLLSNTLFFAFLGLQRDPALFPAVPLDLCKGPAASDGLALYKTQPEVKTQPNAEPDGAARDGPSSNSSFYSSEGEGTDHEGDILDCSGSRPLLLDSEEEEEGCRPGTGFLQAGPRERRDISREQHPHTQAVETPFPAFQSHSGEVFNEPDVFATAPFRSSRKAPDEADVFTKAPFISKGSAALRHPEEADVFLRAPFTKKKSMEELLSHSVPKEPLVFLSPAADIQHRTTPAFQSLDAVVSGPSARPQYPSAGFALLTNLPPSVRAAEEHSPPAGVQPEPGERSPAQAGPQECTLGPVTNSRPFRPQALSKYSRHYSPEDGPGLDVQPIAAYKVVSQTNRQAIAGSVSVAPLAARTTELPAADPFASAPFPSKAAKQKP", "length": 418, "header": "tr|A0A8V0Z182-1|A0A8V0Z2Z3_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=AAK1 PE=1 SV=1 CANONICAL=A0A8V0Z2Z3-1" }, "locus": { "chromosome": "22", "start_pos": 144993, "end_pos": 143740, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042329.1", "url": "https://www.ensembl.org/id/ENSGALT00010042329.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024819.1", "url": "https://www.ensembl.org/id/ENSGALP00010024819.1" } ] } }, { "isoform_ac": "A0A8V0Z187-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3/entry#A0A8V0Z187-1", "sequence": { "sequence": "MKKFFDSRREQGGSGPGSGTSGGGGGSGGPGSGYIGRVFGIGRRQVTVDEVLAEGGFAIVFLVRTNNGMKCALKRMYVNNEYDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEEEIKKYTTLSYRAPEMVNLYSGKLITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRHSQDMHCLIRYMLEPDPDKRPDIYQVSYFAFKLAKKECPVQNVQNSPIPAKLPDPVKASEAAAKKSQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRPTAQAAIQPQGPAALGSGQPSLPASVPQQKAAPQPTSAQPQAKQVSAPQQASQAQPQVPSAQPQATPQHQQQLFLKQQLLQQQQQQQAAYYQQQQVMQAQQFPVMQQGAPAQQQLMQNYYQQQQQQQQMMAQQAAMQQKTAAAAVQQKQQATAPPQPQAQQSAAQPTPQQEQAMQAQIRQQQKPQTTPPTAVQGQKLGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSASTTPSGSPRTSQQNVYNPPDVSTWNPFDDDNFSKLTAEELLNKDFAKLGDGKAPEKMGSSTENLIPGFQPASSAAQADAFGGSSSFTAGSEKLIEGLKSPETALLLPDILPLADPFGSTSDAVNGKPDVAVESLIPGLEAPLPQCLVSQTESVASNRTDSLTGEDSLLDCSLLSNPAADLLDEFAPVAFTAQPHKEDTNLIAGFDAPEGSEKVTEDEFDPIPVLISKNSQGGHSRNNSGSSESSLPNIARSLLLVDQLIDL", "length": 906, "header": "tr|A0A8V0Z187-1|A0A8V0Z2Z3_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=AAK1 PE=1 SV=1 CANONICAL=A0A8V0Z2Z3-1" }, "locus": { "chromosome": "22", "start_pos": 137510, "end_pos": 83131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042334.1", "url": "https://www.ensembl.org/id/ENSGALT00010042334.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024824.1", "url": "https://www.ensembl.org/id/ENSGALP00010024824.1" } ] } }, { "isoform_ac": "A0A8V0Z1M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3/entry#A0A8V0Z1M5-1", "sequence": { "sequence": "MKDTNLIAGFDAPEGSEKVTEDEFDPIPVLISKNSQGLQRDPALFPAVPLDLCKGPAASDGLALYKTQPEVKTQPNAEPDGAARDGPSSNSSFYSSEGEGTDHEGDILDCSGSRPLLLDSEEEEEGCRPGTGFLQAGPRERRDISREQHPHTQAVETPFPAFQSHSGEVFNEPDVFATAPFRSSRKAPDEADVFTKAPFISKGSAALRHPEEADVFLRAPFTKKKSMEELLSHSVPKEPLVFLSPAADIQHRTTPAFQSLDAVVSGPSARPQYPSAGFALLTNLPPSVRAAEEHSPPAGVQPEPGERSPAQAGPQECTLGPVTNSRPFRPQALSKYSRHYSPEDGPGLDVQPIAAYKVVSQTNRQAIAGSVSVAPLAARTTELPAADPFASAPFPSKAAKQKP", "length": 403, "header": "tr|A0A8V0Z1M5-1|A0A8V0Z2Z3_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=AAK1 PE=1 SV=1 CANONICAL=A0A8V0Z2Z3-1" }, "locus": { "chromosome": "22", "start_pos": 144993, "end_pos": 126914, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042327.1", "url": "https://www.ensembl.org/id/ENSGALT00010042327.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024816.1", "url": "https://www.ensembl.org/id/ENSGALP00010024816.1" } ] } }, { "isoform_ac": "A0A8V0Z1N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3/entry#A0A8V0Z1N6-1", "sequence": { "sequence": "MKKFFDSRREQGGSGPGSGTSGGGGGSGGPGSGYIGRVFGIGRRQVTVDEVLAEGGFAIVFLVRTNNGMKCALKRMYVNNEYDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEEEIKKYTTLSYRAPEMVNLYSGKLITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRHSQDMHCLIRYMLEPDPDKRPDIYQVSYFAFKLAKKECPVQNVQNSPIPAKLPDPVKASEAAAKKSQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRPTAQAAIQPQGPAALGSGQPSLPASVPQQKAAPQPTSAQPQAKQVSAPQQASQAQPQVPSAQPQATPQHQQQLFLKQQLLQQQQQQQAAYYQQQQVMQAQQFPVMQQGAPAQQQLMQNYYQQQQQQQQMMAQQAAMQQKTAAAAVQQKQQATAPPQPQAQQSAAQPTPQQEQAMQAQIRQQQKPQTTPPTAVQGQKLGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSASTTPSGSPRTSQQNVYNPPDVSTWNPFDDDNFSKLTAEELLNKDFAKLGDGKAPEKMGSSTENLIPGFQPASSAAQADAFGGSSSFTAGSAEKMKDILSLDASPPLLTVPDPFIPLPLSDTPEKLIEGLKSPETALLLPDILPLADPFGSTSDAVNGKPDVAVESLIPGLEAPLPQCLVSQTESVASNRTDSLTGEDSLLDCSLLSNPAADLLDEFAPVAFTAQPHKDTNLIAGFDAPEGSEKVTEDEFDPIPVLISKNSQGGHSRNNSGSSESSLPNIARSLLLVDQLIDL", "length": 937, "header": "tr|A0A8V0Z1N6-1|A0A8V0Z2Z3_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=AAK1 PE=1 SV=1 CANONICAL=A0A8V0Z2Z3-1" }, "locus": { "chromosome": "22", "start_pos": 137510, "end_pos": 83131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042336.1", "url": "https://www.ensembl.org/id/ENSGALT00010042336.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024826.1", "url": "https://www.ensembl.org/id/ENSGALP00010024826.1" } ] } }, { "isoform_ac": "A0A8V0Z1Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3/entry#A0A8V0Z1Q3-1", "sequence": { "sequence": "MKKFFDSRREQGGSGPGSGTSGGGGGSGGPGSGYIGRVFGIGRRQVTVDEVLAEGGFAIVFLVRTNNGMKCALKRMYVNNEYDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEEEIKKYTTLSYRAPEMVNLYSGKLITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRHSQDMHCLIRYMLEPDPDKRPDIYQVSYFAFKLAKKECPVQNVQNSPIPAKLPDPVKASEAAAKKSQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRPTAQAAIQPQGPAALGSGQPSLPASVPQQKAAPQPTSAQPQAKQVSAPQQASQAQPQVPSAQPQATPQHQQQLFLKQQLLQQQQQQQAAYYQQQQVMQAQQFPVMQQGAPAQQQLMQNYYQQQQQQQQMMAQQAAMQQKTAAAAVQQKQQATAPPQPQAQQSAAQPTPQQEQAMQAQIRQQQKPQTTPPTAVQGQKLGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSASTTPSGSPRTSQQNVYNPPDVSTWNPFDDDNFSKLTAEELLNKDFAKLGDGKAPEKMGSSTENLIPGFQPASSAAQADAFGGSSSFTAGSEDTNLIAGFDAPEGSEKVTEDEFDPIPVLISKNSQGLQRDPALFPAVPLDLCKGPAASDGLALYKTQPEVKTQPNAEPDGAARDGPSSNSSFYSSEGEGTDHEGDILDCSGSRPLLLDSEEEEEGCRPGTGFLQAGPRERRDISREQHPHTQAVETPFPAFQSHSGEVFNEPDVFATAPFRSSRKAPDEADVFTKAPFISKGSAALRHPEEADVFLRAPFTKKKSMEELLSHSVPKEPLVFLSPAADIQHRTTPAFQSLDAVVSGPSARPQYPSAGFALLTNLPPSVRAAEEHSPPAGVQPEPGERSPAQAGPQECTLGPVTNSRPFRPQALSKYSRHYSPEDGPGLDVQPIAAYKVVSQTNRQAIAGSVSVAPLAARTTELPAADPFASAPFPSKAAKQKP", "length": 1137, "header": "tr|A0A8V0Z1Q3-1|A0A8V0Z2Z3_CHICK Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=AAK1 PE=1 SV=1 CANONICAL=A0A8V0Z2Z3-1" }, "locus": { "chromosome": "22", "start_pos": 144993, "end_pos": 83131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042351.1", "url": "https://www.ensembl.org/id/ENSGALT00010042351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024841.1", "url": "https://www.ensembl.org/id/ENSGALP00010024841.1" } ] } }, { "isoform_ac": "A0A8V0Z2X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3/entry#A0A8V0Z2X6-1", "sequence": { "sequence": "CCLFFFPFAFSLFSFFLCLLNPEKLIEGLKSPETALLLPDILPLADPFGSTSDAVNGLQRDPALFPAVPLDLCKGPAASDGLALYKTQPEVKTQPNAEPDGAARDGPSSNSSFYSSEGEGTDHEGDILDCSGSRPLLLDSEEEEEGCRPGTGFLQAGPRERRDISREQHPHTQAVETPFPAFQSHSGEVFNEPDVFATAPFRSSRKAPDEADVFTKAPFISKGSAALRHPEEADVFLRAPFTKKKSMEELLSHSVPKEPLVFLSPAADIQHRTTPAFQSLDAVVSGPSARPQYPSAGFALLTNLPPSVRAAEEHSPPAGVQPEPGERSPAQAGPQECTLGPVTNSRPFRPQALSKYSRHYSPEDGPGLDVQPIAAYKVVSQTNRQAIAGSVSVAPLAARTTELPAADPFASAPFPSKAAKQKP", "length": 423, "header": "tr|A0A8V0Z2X6-1|A0A8V0Z2X6_CHICK Computationally mapped isoform of AP2 associated kinase 1 OS=Gallus gallus OX=9031 GN=AAK1 PE=1 SV=1 CANONICAL=A0A8V0Z2Z3-1" }, "locus": { "chromosome": "22", "start_pos": 144993, "end_pos": 130660, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042326.1", "url": "https://www.ensembl.org/id/ENSGALT00010042326.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024815.1", "url": "https://www.ensembl.org/id/ENSGALP00010024815.1" } ] } }, { "isoform_ac": "A0A8V0Z2Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3/entry#A0A8V0Z2Z3-1", "sequence": { "sequence": "MKKFFDSRREQGGSGPGSGTSGGGGGSGGPGSGYIGRVFGIGRRQVTVDEVLAEGGFAIVFLVRTNNGMKCALKRMYVNNEYDLQVCKREIQIMRDLSGHKNIVGYIDSSINSVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEEEIKKYTTLSYRAPEMVNLYSGKLITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRHSQDMHCLIRYMLEPDPDKRPDIYQVSYFAFKLAKKECPVQNVQNSPIPAKLPDPVKASEAAAKKSQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRPTAQAAIQPQGPAALGSGQPSLPASVPQQKAAPQPTSAQPQAKQVSAPQQASQAQPQVPSAQPQATPQHQQQLFLKQQLLQQQQQQQAAYYQQQQVMQAQQFPVMQQGAPAQQQLMQNYYQQQQQQQQMMAQQAAMQQKTAAAAVQQKQQATAPPQPQAQQSAAQPTPQQEQAMQAQIRQQQKPQTTPPTAVQGQKLGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSASTTPSGSPRTSQQNVYNPPDVSTWNPFDDDNFSKLTAEELLNKDFAKLGDGKAPEKMGSSTENLIPGFQPASSAAQADAFGGSSSFTAGSAEKMKDILSLDASPPLLTVPDPFIPLPLSDTPEKLIEGLKSPETALLLPDILPLADPFGSTSDAVNGKPDVAVESLIPGLEAPLPQCLVSQTESVASNRTDSLTGEDSLLDCSLLSNPAADLLDEFAPVAFTAQPHKEDTNLIAGFDAPEGSEKVTEDEFDPIPVLISKNSQGLQRDPALFPAVPLDLCKGPAASDGLALYKTQPEVKTQPNAEPDGAARDGPSSNSSFYSSEGEGTDHEGDILDCSGSRPLLLDSEEEEEGCRPGTGFLQAGPRERRDISREQHPHTQAVETPFPAFQSHSGEVFNEPDVFATAPFRSSRKAPDEADVFTKAPFISKGSAALRHPEEADVFLRAPFTKKKSMEELLSHSVPKEPLVFLSPAADIQHRTTPAFQSLDAVVSGPSARPQYPSAGFALLTNLPPSVRAAEEHSPPAGVQPEPGERSPAQAGPQECTLGPVTNSRPFRPQALSKYSRHYSPEDGPGLDVQPIAAYKVVSQTNRQAIAGSVSVAPLAARTTELPAADPFASAPFPSKAAKQKP", "length": 1274, "header": "tr|A0A8V0Z2Z3-1|A0A8V0Z2Z3_CHICK Isoform 1 of non-specific serine/threonine protein kinase OS=Gallus gallus OX=9031 GN=AAK1 PE=1 SV=1 CANONICAL=A0A8V0Z2Z3-1" }, "locus": { "chromosome": "22", "start_pos": 144993, "end_pos": 83131, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042340.1", "url": "https://www.ensembl.org/id/ENSGALT00010042340.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024830.1", "url": "https://www.ensembl.org/id/ENSGALP00010024830.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 429, "start_aa": "Thr", "end_pos": 429, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr429", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 560, "start_aa": "Thr", "end_pos": 560, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr560", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:419512", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419512", "resource": "KEGG Pathway" }, { "id": "R-GGA-8856825", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856825", "resource": "Reactome", "description": "Cargo recognition for clathrin-mediated endocytosis" }, { "id": "R-GGA-8856828", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856828", "resource": "Reactome", "description": "Clathrin-mediated endocytosis" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SPM8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTESEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSFFSFKLLKKECPVPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRAMVQPPPQVAGSSNQPGLLASVPQPKTQAPPSQPLPQSQAKQPQAPPAPQQPPSAPAQGLPAQAQATPQHQQQLFLKQQPQPPQPQPQAQAPPVKSLKFYPFYPMCKGRQTVSSQFQAVHPAAQQPAIAQFPAVSQGSSQQQLIQNFYQQQQQQQQQQQLATTLHQQQLLTQQAALQQKTTVAAIQPPQAQPATASQPPPAQEPAQIQAPVRQQPKVQTTPPPAIQGQKLGSLTPPSSPKAQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRASQQNVYNPSEGSTWNPFDDDNFSKLTAEELLNKDFAKLGEGKHPEKLGGSAESLIPGFQPTQGDAFAASSFAAGTAEKRKGGQAVDSSLPLLSVSDPFIPLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIEKADVAVESLIPGLEPPVPQRLPSQTESVASNRTDSLTGEDALIDCSLLSNPTTDLLEEFAPIAISAPAHKAAEDSNLISGFDVPEGSDKVAEDEFDPIPVLITKNPQGGHSRNSSGSSESSLPNLARSLLLVDQLIDL", "length": 968 }, "evidence": [ { "id": "A0A8V0Z2Z3", "url": "https://omabrowser.org/oma/group/A0A8V0Z2Z3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2M2I8-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "AAK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKFFDSRREQGGSGLGSGSSGGGGSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQTEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGNFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQKPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFSKLTAEELLNKDFAKLGEGKHPEKLGGSAESLIPGFQSTQGDAFATTSFSAGTAEKRKGGQTVDSGLPLLSVSDPFIPLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIEKADVAVESLIPGLEPPVPQRLPSQTESVTSNRTDSLTGEDSLLDCSLLSNPTTDLLEEFAPTAISAPVHKAAEDSNLISGFDVPEGSDKVAEDEFDPIPVLITKNPQGGHSRNSSGSSESSLPNLARSLLLVDQLIDL", "length": 961 }, "evidence": [ { "id": "A0A8V0Z2Z3", "url": "https://omabrowser.org/oma/group/A0A8V0Z2Z3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UHJ0-1", "protein_name": "AP2-associated protein kinase 1", "gene_name": "Aak1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKFFDSRREQGSSGLGSGSSGGGGSSSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFALVFLVRTSNGVKCALKRMFVNNEHDLQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFCRGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLHDRGHYVLCDFGSATNKFQNPQAEGVNAVEDEIKKYTTLSYRAPEMVNLYSGKIITTKADIWALGCLLYKLCYFTLPFGESQVAICDGSFTIPDNSRYSQDMHCLIRYMLEPDPDKRPDIYQVSYFSFKLLKKECPVPNVQNSPIPAKLPEPVKASEAAVKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPLPQAAGPSNQPGLLPSVSQPKAQATPSQPLQSSQPKQPQAPPTPQQTPATQTQGLPTQAQATPQHQQQHLLKQQQQQQQQPQQPTAPPQPAGTFYQQQQQQQQQQAQTQQFQAVHPAAQQPVTAQFPVGSQGGAQQQLMQNFYHQQQQQQQQQQQLMAQQAALQQKTAVVVPQSQAQPATAPQAAAAQEPGQIQAPVRQQPKVQTTPPPTIQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNVSNASEGSTWNPFDDDNFSKLTAEELLNKDFAKLGEGKLPEKLGGSAESLIPGFQPTQGDAFTTPSFSAGTAEKRKGGQAVDSGIPLLSVSDPFIPLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIDKADVAVESLIPGLEPPVAQRLPSQTESVTSNRTDSLTGEDSLLDCSLLSNPTAGLLEEFAPIALSAPTHKAAEDSNLISGFGVAEGSEKVAEDEFDPIPVLITKNTQGGHSRNSSGSSESSLPNLARSLLLVDQLIDL", "length": 959 }, "evidence": [ { "id": "A0A8V0Z2Z3", "url": "https://omabrowser.org/oma/group/A0A8V0Z2Z3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ], "pmid": "" }, { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ], "pmid": "" }, { "name": "AP-2 adaptor complex binding", "id": "GO:0035612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035612", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ], "pmid": "" }, { "name": "positive regulation of Notch signaling pathway", "id": "GO:0045747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045747", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ], "pmid": "" }, { "name": "regulation of clathrin-dependent endocytosis", "id": "GO:2000369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000369", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z3" } ], "pmid": "" }, { "name": "presynaptic endocytosis", "id": "GO:0140238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140238", "evidence": 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"A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] }, { "id": "R-GGA-8856808", "name": "Recruitment of AP-2 complex and clathrin", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "P26990-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8856808", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856808" } ] }, { "id": "R-GGA-8856813", "name": "AAK1 phosphorylates AP-2 mu subunit at T156", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8856813", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8856813" } ] }, { "id": "R-GGA-8866283", "name": "ARBB recruits GPCRs into clathrin-coated pits", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8866283", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8866283" } ] }, { "id": "R-GGA-8867756", "name": "CLASP proteins and cargo are recruited to the nascent clathrin-coated pit", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X9Y7-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8867756", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8867756" } ] }, { "id": "R-GGA-8868071", "name": "Clathrin recruits PIK3C2A", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X9Y7-1", "A0A8V0ZLS9-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8868071", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8868071" } ] }, { "id": "R-GGA-8868072", "name": "Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X9Y7-1", "A0A8V0ZLS9-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8868072", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8868072" } ] }, { "id": "R-GGA-8868230", "name": "SNX9 recruits components of the actin polymerizing machinery", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X9Y7-1", "P53478-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "Q5ZMQ2-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8868230", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8868230" } ] }, { "id": "R-GGA-8868648", "name": "SYNJ hydrolyze PI(4,5)P2 to PI(4)P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XJN9-1", "A0A8V1ACG4-1", "A0A8V0X9Y7-1", "P53478-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "A0A8V0YRC1-1", "A0A8V0YTL7-1", "Q5ZMQ2-1", "A0A8V0Y798-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8868648", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8868648" } ] }, { "id": "R-GGA-8868651", "name": "Endophilins recruit synaptojanins to the clathrin-coated pit", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XJN9-1", "A0A8V1ACG4-1", "A0A8V0X9Y7-1", "P53478-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "A0A8V0YRC1-1", "A0A8V0YTL7-1", "Q5ZMQ2-1", "A0A8V0Y798-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8868651", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8868651" } ] }, { "id": "R-GGA-8868658", "name": "HSPA8-mediated ATP hydrolysis promotes vesicle uncoating", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "clathrin-coated endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XJN9-1", "A0A8V1ACG4-1", "A0A8V0YRN4-1", "A0A8V0X9Y7-1", "P53478-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "A0A8V0YRC1-1", "A0A8V0YTL7-1", "Q5ZMQ2-1", "A0A8V0Y798-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8868658", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8868658" } ] }, { "id": "R-GGA-8868659", "name": "Clathrin recruits auxilins to the clathrin-coated vesicle", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "clathrin-coated endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XJN9-1", "A0A8V1ACG4-1", "A0A8V0YRN4-1", "A0A8V0X9Y7-1", "P53478-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "A0A8V0YRC1-1", "A0A8V0YTL7-1", "Q5ZMQ2-1", "A0A8V0Y798-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8868659", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8868659" } ] }, { "id": "R-GGA-8868660", "name": "Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "clathrin-coated endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XJN9-1", "A0A8V1ACG4-1", "A0A8V0YRN4-1", "A0A8V0X9Y7-1", "P53478-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "A0A8V0YRC1-1", "A0A8V0YTL7-1", "Q5ZMQ2-1", "A0A8V0Y798-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8868660", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8868660" } ] }, { "id": "R-GGA-8868661", "name": "Dynamin-mediated GTP hydrolysis promotes vesicle scission", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "plasma membrane, clathrin-coated endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XJN9-1", "A0A8V1ACG4-1", "A0A8V0X9Y7-1", "P53478-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "A0A8V0YRC1-1", "A0A8V0YTL7-1", "Q5ZMQ2-1", "A0A8V0Y798-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8868661", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8868661" } ] }, { "id": "R-GGA-8871193", "name": "Dissociation of AAK1 and dephosphorylation of AP-2 mu2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "clathrin-coated endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XJN9-1", "A0A8V1ACG4-1", "A0A8V0YRN4-1", "A0A8V0X9Y7-1", "P53478-1", "Q5ZHW4-1", "Q98932-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "A0A8V0YRC1-1", "A0A8V0YTL7-1", "Q5ZMQ2-1", "A0A8V0Y798-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8871193", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8871193" } ] }, { "id": "R-GGA-8871194", "name": "RAB5 and GAPVD1 bind AP-2", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.
The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.
More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "clathrin-coated endocytic vesicle membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XJN9-1", "A0A8V1ACG4-1", "A0A8V0YRN4-1", "A0A8V0X9Y7-1", "P53478-1", "Q5ZHW4-1", "Q98932-1", "A0A8V0ZY53-1", "A0A8V0XNF4-1", "A0A8V0YRC1-1", "A0A8V0YTL7-1", "Q5ZMQ2-1", "A0A8V0Y798-1", "A0A8V0Z2Z3-1" ], "evidence": [ { "id": "R-GGA-8871194", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8871194" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PXN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PXN4" } ] } ] }, { "uniprot_ac": "A0A1L1RWI9", "gene_name": "CAMK4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A1L1RWI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RWI9" } ] } ] }, { "uniprot_ac": "A0A3Q2TRY2", "gene_name": "TAOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TRY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TRY2" } ] } ] }, { "uniprot_ac": "A0A3Q2TUS7", "gene_name": "TLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TUS7" } ] } ] }, { "uniprot_ac": "A0A3Q2TV19", "gene_name": "UHMK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2TV19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TV19" } ] } ] }, { "uniprot_ac": "A0A3Q2TWZ8", "gene_name": "MAP3K20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TWZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3Q2TWZ8", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF44" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UF44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UF44" } ] } ] }, { "uniprot_ac": "A0A3Q2UI52", "gene_name": "LATS2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q2UI52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI52" } ] } ] }, { "uniprot_ac": "A0A3Q2UI62", "gene_name": "CDK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3Q2UI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UI62" } ] } ] }, { "uniprot_ac": "A0A3Q3A664", "gene_name": "CDK17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3Q3A664", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3A664" } ] } ] }, { "uniprot_ac": "A0A3Q3AAD7", "gene_name": "STK35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3Q3AAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AAD7" } ] } ] }, { "uniprot_ac": "A0A3Q3B2F1", "gene_name": "PKN3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A3Q3B2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3B2F1" } ] } ] }, { "uniprot_ac": "A0A8V0X1Q7", "gene_name": "MELK", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X1Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X1Q7" } ] } ] }, { "uniprot_ac": "A0A8V0X2Y2", "gene_name": "MAPK12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X2Y2" } ] } ] }, { "uniprot_ac": "A0A8V0X3D6", "gene_name": "LOC100858386", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0X3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X3D6" } ] } ] }, { "uniprot_ac": "A0A8V0X4P0", "gene_name": "CDKL5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0X4P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4P0" } ] } ] }, { "uniprot_ac": "A0A8V0X4Q3", "gene_name": "ICK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X4Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X4Q3" } ] } ] }, { "uniprot_ac": "A0A8V0X5Z8", "gene_name": "NEK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X5Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X5Z8" } ] } ] }, { "uniprot_ac": "A0A8V0X6T4", "gene_name": "LOC107050692", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X6T4" } ] } ] }, { "uniprot_ac": "A0A8V0X7R2", "gene_name": "SBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X7R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X7R2" } ] } ] }, { "uniprot_ac": "A0A8V0X8M1", "gene_name": "TRIO", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0X8M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X8M1" } ] } ] }, { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] }, { "uniprot_ac": "A0A8V0XAH9", "gene_name": "NEK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XAH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XAH9" } ] } ] }, { "uniprot_ac": "A0A8V0XB58", "gene_name": "CAMK2D", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0XB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XB58" } ] } ] }, { "uniprot_ac": "A0A8V0XBZ0", "gene_name": "STK32C", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": 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"https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XCV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCV5" } ] } ] }, { "uniprot_ac": "A0A8V0XCY6", "gene_name": "TTK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0XCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XCY6" } ] } ] }, { "uniprot_ac": "A0A8V0XDR5", "gene_name": "IRAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XDR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XDR5" } ] } ] }, { "uniprot_ac": "A0A8V0XE48", "gene_name": "ROCK2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8V0XE48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XE48" } ] } ] }, { "uniprot_ac": "A0A8V0XEA3", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XEA3" } ] } ] }, { "uniprot_ac": "A0A8V0XFW1", "gene_name": "SGK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFW1" } ] } ] }, { "uniprot_ac": "A0A8V0XFX2", "gene_name": "NEK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XJN9", "gene_name": "SYNJ2", "activity": [ { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "A0A8V0XJN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJN9" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "A0A8V0XJN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XJN9" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNF4", "gene_name": "EGFR", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8V0XNF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNF4" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { 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"A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": 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} ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", 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H(+).", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCY8" } ] } ] }, { "uniprot_ac": "A0A8V0YDH4", "gene_name": "ALPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YDH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YDH4" } ] } ] }, { "uniprot_ac": "A0A8V0YF83", "gene_name": "WNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YF83" } ] } ] }, { "uniprot_ac": "A0A8V0YFH4", "gene_name": "NRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC1", "gene_name": "OCRL", "activity": [ { "ec_number": "3.1.3.86", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A8V0YRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC1" } ] }, { "ec_number": "3.1.3.56", "activity": "1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.", "evidence": [ { "id": "A0A8V0YRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC1" } ] }, { "ec_number": "3.1.3.36", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate.", "evidence": [ { "id": "A0A8V0YRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC1" } ] }, { "ec_number": "3.1.3.86", "activity": "", "evidence": [ { "id": "A0A8V0YRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC1" } ] }, { "ec_number": "3.1.3.36", "activity": "", "evidence": [ { "id": "A0A8V0YRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC1" } ] }, { "ec_number": "3.1.3.56", "activity": "", "evidence": [ { "id": "A0A8V0YRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC1" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL7", "gene_name": "DNM3", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0YTL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL7" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V0YTL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL7" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] } ] }, { "uniprot_ac": "A0A8V0Z9J0", "gene_name": "CIT", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z9J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9J0" } ] } ] }, { "uniprot_ac": "A0A8V0ZA06", "gene_name": "CDKL1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA06", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLS9", "gene_name": "PIK3C2A", "activity": [ { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS9" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS9" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS9" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A8V0ZLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS9" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8V0ZLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS9" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8V0ZLS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLS9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZY53", "gene_name": "CBL", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A8V0ZY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY53" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A8V0ZY53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZY53" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACG4", "gene_name": "DNM1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V1ACG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACG4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A8V1ACG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACG4" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P26990", "gene_name": "ARF6", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "P26990", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26990" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "P26990", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P26990" } ] } ] }, { "uniprot_ac": "P53478", "gene_name": "", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "P53478", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53478" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", 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"Protein Classification" ] }, { "id": "A0A8V0Z1T3", "url": "https://www.orthodb.org/?gene=A0A8V0Z1T3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z339", "url": "https://www.orthodb.org/?gene=A0A8V0Z339", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15109:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15109:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15914", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15914", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YUX9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YUX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YUX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1T3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z339", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z339", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z339-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z339-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSLNGTQFTDSSVGSEFTGVSQTPFTFGLGQRAPYTTGEHCLLCRSERKDSSLSESGIKNSSKTALSTSPKANNMLHLPLWVCPDCRRTVEKEERHATIEQSLVSQDFLLHMPLGNSGSQQESVGGGRITVGAQTVPAADLNNSSPSDIACNCEACNERREISAETERESQQLQNYWSEVRYMVRCIYRQAGTPLADDQDQSLVPDKEGMKELVDRLCERDPYQLYQRLEQQAREYVLEMKVRLLRHLSLGSKVASTLAIQGPPQAHQFISLLLEEYSALCQAACTISAFLVTLENEHLKKFQVTWELHNKHLFENLVFSEPLLQNSLPTLVSQLRLGTTHDSCSEDMYSTLLQRYHQLEQEMGQVAEAWLECQKRIDDYVDEQMAMKTKQRMLKEDWEFFKQRRFIEEQLNNKKALAGENNFTDTMRHMLSSRLSMPDCPNCNYRRRCTCDDCSLSHILTCGIMDSPITDDIHINPLPLQIDSAPDYLSEIRPPSMSSASSGSGSSSPITIQQHPRLILADNGSAPTFGSDDEDVAPLSAKFADIYPLNNYDDAEVVANMNGIHSELNGGDENMALKDESPQVSSTSSSSSEADDEEADGESSGEPPGTQKEEMSLGKRALRKDEAKMDSPPPSYPSQQADQGPNACECHVCKQEASGLTASALATGRLPAGHQFMNPEKPAHPALHLYPHIHGHIPLHTIPHLPRPLIHPTLYTASPFTHNKALPPAPVQNHSNKHQVFNASLQDHIYPSCFGSTPDWNSSKFISLWGSEMMNDKNWNPATFLPDTIPGNDILTPALSEIRPEALPTTSSNEGSAVTDGKEKKNAAKKKCLYNFQDAFMEANKVVMATSSATSSVSCTATTVQSSSNQFKVSSKRPSSIGEVFHNINKEDHRHSAPVAPRNSPTSLASLPSLSPAALSPASTPHLPNLAAPSFPKTAATAPGFVDPHSGLCPTTVVPPTSTTDSSVSAPPSVCSDPDCEGHRCENSNTYDHQQYDGEESQDEDSCSEHSSSTSTSTNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKPDQISERESVVDHRKVEDLLQFINSSETKPVSSSRAAKRARHKQRKLEEKARLEAEAREREHHQLLEEQRRREEEEEERLKQELQRLQELQQLRAVKKKKKERTNKDCQKVDVLTQNCQTAKESVPNAPEDIQNGTLEQSEKIETSSGSLSRHVNHTEQRPLSDTGCEPSNAVNTRDSKLLYQKEGSVKQHEPLSFLLDIMHQHKEGNNKQKLKQINKQCAEQVKKPVESSKASEIQTKTRNQIESKAKAELPVLAEPKKEEKKLTNNNNNKKQLNHIKEEKAPITSESPSPSEQQQNNKLILADSPQPKGKNKKNKKKKGDKVNNSIDDVFLPKDIDLDSVEMDETEREVEYFKRFCLDSARQTRQRLSINWSNFSLKKTTFAAH", "length": 1456, "header": "tr|A0A8V0Z339-1|A0A8V0Z339_CHICK Isoform 1 of Family with sequence similarity 193 member A OS=Gallus gallus OX=9031 GN=FAM193A PE=3 SV=1 CANONICAL=A0A8V0Z339-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YUX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z339/entry#A0A8V0YUX9-1", "sequence": { "sequence": "MLHLPLWVCPDCRRTVEKEERHATIEQSLVSQDFLLHMPLGNSGSQQESVGGGRITVGAQTVPAADLNNSSPSDIACNCEACNERREISAETERESQQLQNYWSEVRYMVRCIYRQAGTPLADDQDQSLVPDKEGMKELVDRLGTTHDSCSEDMYSTLLQRYHQLEQEMGQVAEAWLECQKRIDDYVDEQMAMKTKQRMLKEDWEFFKQRRFIEEQLNNKKALAGENNFTDTMRHMLSSRLSMPDCPNCNYRRRCTCDDCSLSHILTCGIMDSPITDDIHINPLPLQIDSAPDYLSEIRPPSMSSASSGSGSSSPITIQQHPRLILADNGSAPTFGSDDEDVAPLSAKFADIYPLNNYDDAEVVANMNGIHSELNGGDENMALKDESPQVSSTSSSSSEADDEEADGESSGEPPGTQKEEMSLGKRALRKDEAKMDSPPPSYPSQQADQGPNACECHVCKQEASGLTASALATGRLPAGHQFMNPEKPAHPALHLYPHIHGHIPLHTIPHLPRPLIHPTLYTASPFTHNKALPPAPVQNHSNKHQVFNASLQDHIYPSCFGSTPDWNSSKFISLWGSEMMNDKNWNPATFLPDTIPGNDILTPALSEIRPEALPTTSSNEGSAVTDGKEKKNAAKKKCLYNFQDAFMEANKVVMATSSATSSVSCTATTVQSSSNQFKVSSKRPSSIGEVFHNINKEDHRHSAPVAPRNSPTSLASLPSLSPAALSPASTPHLPNLAAPSFPKTAATAPGFVDPHSGLCPTTVVPPTSTTDSSVSAPPSVCSDPDCEGHRCENSNTYDHQQYDGEESQDEDSCSEHSSSTSTSTNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKPDQISERESVVDHRKVEDLLQFINSSETKPVSSSRAAKRARHKQRKLEEKARLEAEAREREHHQLLEEQRRREEEEEERLKQELQRLQELQQLRAVKKKKKERTNKDCQKVDVLTQNCQTAKESVPNAPEDIQNGTLEQSEKIETSSGSLSRHVNHTEQRPLSDTGCEPSNAVNTRDSKLLYQKEGSVKQHEPLSFLLDIMHQHKEGNNKQKLKQINKQCAEQVKKPVESSKASEIQTKTRNQIESKAKAELPVLAEPKKEEKKLTNNNNNKKQLNHIKEEKAPITSESPSPSEQQQNNKLILADSPQPKGKNKKNKKKKGDKVNNSIDDVFLPKDIDLDSVEMDETEREVEYFKRFCLDSARQTRQRLSINWSNFSLKKTTFAAH", "length": 1261, "header": "tr|A0A8V0YUX9-1|A0A8V0Z339_CHICK Computationally mapped isoform of Family with sequence similarity 193 member A OS=Gallus gallus OX=9031 GN=FAM193A PE=3 SV=1 CANONICAL=A0A8V0Z339-1" }, "locus": { "chromosome": "4", "start_pos": 82037902, "end_pos": 81998062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042382.1", "url": "https://www.ensembl.org/id/ENSGALT00010042382.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024872.1", "url": "https://www.ensembl.org/id/ENSGALP00010024872.1" } ] } }, { "isoform_ac": "A0A8V0Z1T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z339/entry#A0A8V0Z1T3-1", "sequence": { "sequence": "MDYSTKENEHLKKFQVTWELHNKHLFENLVFSEPLLQNSLPTLVSQLRLGTTHDSCSEDMYSTLLQRYHQLEQEMGQVAEAWLECQKRIDDYVDEQMAMKTKQRMLKEDWEFFKQRRFIEEQLNNKKALAGENNFTDTMRHMLSSRLSMPDCPNCNYRRRCTCDDCSLSHILTCGIMDSPITDDIHINPLPLQIDSAPDYLSEIRPPSMSSASSGSGSSSPITIQQHPRLILADNGSAPTFGSDDEDVAPLSAKFADIYPLNNYDDAEVVANMNGIHSELNGGDENMALKDESPQVSSTSSSSSEADDEEADGESSGEPPGTQKEEMSLGKRALRKDEAKMDSPPPSYPSQQADQGPNACECHVCKQEASGLTASALATGRLPAGHQFMNPEKPAHPALHLYPHIHGHIPLHTIPHLPRPLIHPTLYTASPFTHNKALPPAPVQNHSNKHQVFNASLQDHIYPSCFGSTPDWNSSKFISLWGSEMMNDKNWNPATFLPDTIPGNDILTPALSEIRPEALPTTSSNEGSAVTDGKEKKNAAKKKCLYNFQDAFMEANKVVMATSSATSSVSCTATTVQSSSNQFKVSSKRPSSIGEVFHNINKEDHRHSAPVAPRNSPTSLASLPSLSPAALSPASTPHLPNLAAPSFPKTAATAPGFVDPHSGLCPTTVVPPTSTTDSSVSAPPSVCSDPDCEGHRCENSNTYDHQQYDGEESQDEDSCSEHSSSTSTSTNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKPDQISERESVVDHRKVEDLLQFINSSETKPVSSSRAAKRARHKQRKLEEKARLEAEAREREHHQLLEEQRRREEEEEERLKQELQRLQELQQLRAVKKKKKERTNKDCQKVDVLTQNCQTAKESVPNAPEDIQNGTLEQSEKIETSSGSLSRHVNHTEQRPLSDTGCEPSNAVNTRDSKLLYQKEGSVKQHEPLSFLLDIMHQHKEGNNKQKLKQINKQCAEQVKKPVESSKASEIQTKTRNQIESKAKAELPVLAEPKKEEKKLTNNNNNKKQLNHIKEEKAPITSESPSPSEQQQNNKLILADSPQPKGKNKKNKKKKGDKVNNSIDDVFLPKDIDLDSVEMDETEREVEYFKRFCLDSARQTRQRLSINWSNFSLKKTTFAAH", "length": 1167, "header": "tr|A0A8V0Z1T3-1|A0A8V0Z339_CHICK Computationally mapped isoform of Family with sequence similarity 193 member A OS=Gallus gallus OX=9031 GN=FAM193A PE=3 SV=1 CANONICAL=A0A8V0Z339-1" }, "locus": { "chromosome": "4", "start_pos": 82030736, "end_pos": 81998062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042381.1", "url": "https://www.ensembl.org/id/ENSGALT00010042381.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024871.1", "url": "https://www.ensembl.org/id/ENSGALP00010024871.1" } ] } }, { "isoform_ac": "A0A8V0Z339-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z339/entry#A0A8V0Z339-1", "sequence": { "sequence": "MVSLNGTQFTDSSVGSEFTGVSQTPFTFGLGQRAPYTTGEHCLLCRSERKDSSLSESGIKNSSKTALSTSPKANNMLHLPLWVCPDCRRTVEKEERHATIEQSLVSQDFLLHMPLGNSGSQQESVGGGRITVGAQTVPAADLNNSSPSDIACNCEACNERREISAETERESQQLQNYWSEVRYMVRCIYRQAGTPLADDQDQSLVPDKEGMKELVDRLCERDPYQLYQRLEQQAREYVLEMKVRLLRHLSLGSKVASTLAIQGPPQAHQFISLLLEEYSALCQAACTISAFLVTLENEHLKKFQVTWELHNKHLFENLVFSEPLLQNSLPTLVSQLRLGTTHDSCSEDMYSTLLQRYHQLEQEMGQVAEAWLECQKRIDDYVDEQMAMKTKQRMLKEDWEFFKQRRFIEEQLNNKKALAGENNFTDTMRHMLSSRLSMPDCPNCNYRRRCTCDDCSLSHILTCGIMDSPITDDIHINPLPLQIDSAPDYLSEIRPPSMSSASSGSGSSSPITIQQHPRLILADNGSAPTFGSDDEDVAPLSAKFADIYPLNNYDDAEVVANMNGIHSELNGGDENMALKDESPQVSSTSSSSSEADDEEADGESSGEPPGTQKEEMSLGKRALRKDEAKMDSPPPSYPSQQADQGPNACECHVCKQEASGLTASALATGRLPAGHQFMNPEKPAHPALHLYPHIHGHIPLHTIPHLPRPLIHPTLYTASPFTHNKALPPAPVQNHSNKHQVFNASLQDHIYPSCFGSTPDWNSSKFISLWGSEMMNDKNWNPATFLPDTIPGNDILTPALSEIRPEALPTTSSNEGSAVTDGKEKKNAAKKKCLYNFQDAFMEANKVVMATSSATSSVSCTATTVQSSSNQFKVSSKRPSSIGEVFHNINKEDHRHSAPVAPRNSPTSLASLPSLSPAALSPASTPHLPNLAAPSFPKTAATAPGFVDPHSGLCPTTVVPPTSTTDSSVSAPPSVCSDPDCEGHRCENSNTYDHQQYDGEESQDEDSCSEHSSSTSTSTNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKPDQISERESVVDHRKVEDLLQFINSSETKPVSSSRAAKRARHKQRKLEEKARLEAEAREREHHQLLEEQRRREEEEEERLKQELQRLQELQQLRAVKKKKKERTNKDCQKVDVLTQNCQTAKESVPNAPEDIQNGTLEQSEKIETSSGSLSRHVNHTEQRPLSDTGCEPSNAVNTRDSKLLYQKEGSVKQHEPLSFLLDIMHQHKEGNNKQKLKQINKQCAEQVKKPVESSKASEIQTKTRNQIESKAKAELPVLAEPKKEEKKLTNNNNNKKQLNHIKEEKAPITSESPSPSEQQQNNKLILADSPQPKGKNKKNKKKKGDKVNNSIDDVFLPKDIDLDSVEMDETEREVEYFKRFCLDSARQTRQRLSINWSNFSLKKTTFAAH", "length": 1456, "header": "tr|A0A8V0Z339-1|A0A8V0Z339_CHICK Isoform 1 of Family with sequence similarity 193 member A OS=Gallus gallus OX=9031 GN=FAM193A PE=3 SV=1 CANONICAL=A0A8V0Z339-1" }, "locus": { "chromosome": "4", "start_pos": 82057765, "end_pos": 81998062, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042385.1", "url": "https://www.ensembl.org/id/ENSGALT00010042385.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024875.1", "url": "https://www.ensembl.org/id/ENSGALP00010024875.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1094, "end_pos": 1096, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1204, "end_pos": 1206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1225, "end_pos": 1227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1395, "end_pos": 1397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1442, "end_pos": 1444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1445, "end_pos": 1447, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 743, "end_pos": 745, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z339" }, { "id": "PF15914", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15914" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM193 C-terminal", "eco_id": "ECO_0000259", "start_pos": 1399, "end_pos": 1455, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1094, "end_pos": 1096 }, { "start_pos": 1204, "end_pos": 1206 }, { "start_pos": 1225, "end_pos": 1227 }, { "start_pos": 1395, "end_pos": 1397 }, { "start_pos": 143, "end_pos": 145 }, { "start_pos": 1442, "end_pos": 1444 }, { "start_pos": 1445, "end_pos": 1447 }, { "start_pos": 144, "end_pos": 146 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 524, "end_pos": 526 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 734, "end_pos": 736 }, { "start_pos": 743, "end_pos": 745 }, { "start_pos": 762, "end_pos": 764 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3M8-1", "uniprot_ac": "A0A8V0Z3M8", "uniprot_id": "A0A8V0Z3M8_CHICK", "mass": { "chemical_mass": 57325.0, "monoisotopic_mass": 57325.0 }, "refseq": {}, "gene_names": [ { "name": "ZBTB8AL", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 8A", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YVJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVJ7#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A1D5PNE1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE1#function" }, { "database": "UniProtKB", "id": "A0A1D5P468", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P468#function" }, { "database": "UniProtKB", "id": "A0A1D5PHH3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHH3#function" }, { "database": "UniProtKB", "id": "A0A8V0Z3M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB8AL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z3M8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3M8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000038896", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000038896", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18329", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18329", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "419662", "url": "https://www.ncbi.nlm.nih.gov/gene/419662", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:419662", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419662", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WVWEEAS", "url": "https://omabrowser.org/oma/group/WVWEEAS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PNE1", "url": "https://www.orthodb.org/?gene=A0A1D5PNE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5P468", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P468", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P468-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P468-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHH3", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PHH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PHH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNE1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PNE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PNE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YVJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YVJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQAYRTGGFLAERKTFHCSLIGMEISSHQFHLLEQLNEQRKQDLFCDCSILVEGKVFRAHRNVLFASSGYFKMLLSQSSKDTSQPTVATFEVFSPETFMVILDFVYSGILPLTGQNVIEVMSAASYLQMTDILNVCKTFIKSSLDINEKEKDHYLSLSAKSTNGEPAHASLYRSRRKAKSNPRRSYSIPDEKADVVNENSWSSYSTYLSSQVILQRAETQLSKRGRKQGSARKRRKHLGLSQTRDFVPCKANKAERAEGCTASDCNHNSRAKEEAEFDAENDVDHDDDGYNHESEVTPKRWSVAQLEELSQTSEFMELKAEELYSSVPTVLGVMSSWNEDDLPRLRFKCPFCTHTVKRRADLKRHLRCHTGERPYPCEACGKRFTRLEHLRNHFQTIHQAGKLICRKCKRQVSEQTGCVVQQGTRRYRLCHNCLTETSLEGVPEGVDAEHCPASSGGSKHSRWALEDDQKSDGGAVEEEPYNLVVRRGTDSPADEADEKVKPNLR", "length": 505, "header": "tr|A0A8V0Z3M8-1|A0A8V0Z3M8_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 8A OS=Gallus gallus OX=9031 GN=ZBTB8AL PE=4 SV=1 CANONICAL=A0A8V0Z3M8-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P468-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8/entry#A0A1D5P468-1", "sequence": { "sequence": "MEISSHQFHLLEQLNEQRKQDLFCDCSILVEGKVFRAHRNVLFASSGYFKMLLSQSSKDTSQPTVATFEVFSPETFMVILDFVYSGILPLTGQNVIEVMSAASYLQMTDILNVCKTFIKSSLDINEKEKDHYLSLSAKSTNGEPAHASLYRSRRKAKSNPRRSYSIPDEKADVVNENSWSSYSTYLSSQVILQRAETQLSKRGRKQGSARKRRKHLGLSQTRDFVPCKANKAERAEGCTASDCNHNSRAKEEAEFDAENDVDHDDDGYNHESEVTPKRWSVAQLEELSQTSEFMELKAEELYSSVPTVLGVMSSWNEDDLPRLRFKCPFCTHTVKRRADLKRHLRCHTGERPYPCEACGKRFTRLEHLRNHFQTIHQAGKLICRKCKRQVSEQTGCVVQQGTRRYRLCHNCLTETSLEGVPEGVDAEHCPASSGGSKHSRWALEDDQKSDGGAVEEEPYNLVVRRGTDSPADEADEKICMAE", "length": 482, "header": "tr|A0A1D5P468-1|A0A8V0Z3M8_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 8A OS=Gallus gallus OX=9031 GN=ZBTB8AL PE=4 SV=2 CANONICAL=A0A8V0Z3M8-1" }, "locus": { "chromosome": "23", "start_pos": 5587395, "end_pos": 5582853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042608.1", "url": "https://www.ensembl.org/id/ENSGALT00010042608.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025098.1", "url": "https://www.ensembl.org/id/ENSGALP00010025098.1" } ] } }, { "isoform_ac": "A0A1D5PHH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8/entry#A0A1D5PHH3-1", "sequence": { "sequence": "MEISSHQFHLLEQLNEQRKQDLFCDCSILVEGKVFRAHRNVLFASSGYFKMLLSQSSKDTSQPTVATFEVFSPETFMVILDFVYSGILPLTGQNVIEVMSAASYLQMTDILNVCKTFIKSSLDINEKEKDHYLSLSAKSTNGEPAHASLYRSRRKAKSNPRRSYSIPDEKADVVNENSWSSYSTYLSSQVILQRAETQLSKRGRKQGSARKRRKHLGLSQTRDFVPCKANKAERAEGCTASDCNHNSRAKEEAEFDAENDVDHDDDGYNHESEVTPKRWSVAQLEELSQTSEFMELKAEELYSSVPTVLGVMSSWNEDDLPRLRFKCPFCTHTVKRRADLKRHLRCHTGERPYPCEACGKRFTRLEHLRNHFQTIHQAGKLICRKCKRQRPAWRASLKAWMRSTALPAPGEANIPGGLWRMIRSRMAAQWRKSRTIWLSDVVPTALQMRQMKR", "length": 453, "header": "tr|A0A1D5PHH3-1|A0A8V0Z3M8_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 8A OS=Gallus gallus OX=9031 GN=ZBTB8AL PE=4 SV=1 CANONICAL=A0A8V0Z3M8-1" }, "locus": { "chromosome": "23", "start_pos": 5585316, "end_pos": 5582853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042600.1", "url": "https://www.ensembl.org/id/ENSGALT00010042600.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025090.1", "url": "https://www.ensembl.org/id/ENSGALP00010025090.1" } ] } }, { "isoform_ac": "A0A1D5PNE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8/entry#A0A1D5PNE1-1", "sequence": { "sequence": "MEISSHQFHLLEQLNEQRKQDLFCDCSILVEGKVFRAHRNVLFASSGYFKMLLSQSSKDTSQPTVATFEVFSPETFMVILDFVYSGILPLTGQNVIEVMSAASYLQMTDILNVCKTFIKSSLDINEKEKDHYLSLSAKSTNGEPAHASLYRSRRKAKSNPRRSYSIPDEKADVVNENSWSSYSTYLSSQVILQRAETQLSKRGRKQGSARKRRKHLGLSQTRDFVPCKANKAERAEGCTASDCNHNSRAKEEAEFDAENDVDHDDDGYNHESEVTPKRWSVAQLEELSQTSEFMELKAEELYSSVPTVLGVMSSWNEDDLPRLRFKCPFCTHTVKRRADLKRHLRCHTGERPYPCEACGKRFTRLEHLRNHFQTIHQAGKLICRKCKRQVSEQTGCVVQQGTRRYRLCHNCLTETSLEGVPEGVDAEHCPASSGGSKHSRWALEDDQKSDGGAVEEEPYNLVVRRGTDSPADEADEKVKPNLR", "length": 483, "header": "tr|A0A1D5PNE1-1|A0A8V0Z3M8_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 8A OS=Gallus gallus OX=9031 GN=ZBTB8AL PE=4 SV=1 CANONICAL=A0A8V0Z3M8-1" }, "locus": { "chromosome": "23", "start_pos": 5585333, "end_pos": 5582853, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042605.1", "url": "https://www.ensembl.org/id/ENSGALT00010042605.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025095.1", "url": "https://www.ensembl.org/id/ENSGALP00010025095.1" } ] } }, { "isoform_ac": "A0A8V0YVJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8/entry#A0A8V0YVJ7-1", "sequence": { "sequence": "MEISSHQFHLLEQLNEQRKQDLFCDCSILVEGKVFRAHRNVLFASSGYFKMLLSQSSKDTSQPTVATFEVFSPETFMVILDFVYSGILPLTGQNVIEVMSAASYLQMTDILNVCKTFIKSSLDINEKEKDHYLSLSAKSTNGEPAHASLYRSRRKAKSNPRRSYSIPDEKADVVNENSWSSYSTYLSSQVILQRAETQLSKRGRKQGSARKRRKHLGLSQTRDFVPCKANKAERAEGCTASDCNHNSRAKEEAEFDAENDVDHDDDGYNHESEVTPKRWSVAQLEELSQTSEFMELKAEELYSSVPTVLGVMSSWNEGKKHI", "length": 322, "header": "tr|A0A8V0YVJ7-1|A0A8V0Z3M8_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 8A OS=Gallus gallus OX=9031 GN=ZBTB8AL PE=4 SV=1 CANONICAL=A0A8V0Z3M8-1" }, "locus": { "chromosome": "23", "start_pos": 5586002, "end_pos": 5585037, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042604.1", "url": "https://www.ensembl.org/id/ENSGALT00010042604.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025094.1", "url": "https://www.ensembl.org/id/ENSGALP00010025094.1" } ] } }, { "isoform_ac": "A0A8V0Z3M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8/entry#A0A8V0Z3M8-1", "sequence": { "sequence": "MQAYRTGGFLAERKTFHCSLIGMEISSHQFHLLEQLNEQRKQDLFCDCSILVEGKVFRAHRNVLFASSGYFKMLLSQSSKDTSQPTVATFEVFSPETFMVILDFVYSGILPLTGQNVIEVMSAASYLQMTDILNVCKTFIKSSLDINEKEKDHYLSLSAKSTNGEPAHASLYRSRRKAKSNPRRSYSIPDEKADVVNENSWSSYSTYLSSQVILQRAETQLSKRGRKQGSARKRRKHLGLSQTRDFVPCKANKAERAEGCTASDCNHNSRAKEEAEFDAENDVDHDDDGYNHESEVTPKRWSVAQLEELSQTSEFMELKAEELYSSVPTVLGVMSSWNEDDLPRLRFKCPFCTHTVKRRADLKRHLRCHTGERPYPCEACGKRFTRLEHLRNHFQTIHQAGKLICRKCKRQVSEQTGCVVQQGTRRYRLCHNCLTETSLEGVPEGVDAEHCPASSGGSKHSRWALEDDQKSDGGAVEEEPYNLVVRRGTDSPADEADEKVKPNLR", "length": 505, "header": "tr|A0A8V0Z3M8-1|A0A8V0Z3M8_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 8A OS=Gallus gallus OX=9031 GN=ZBTB8AL PE=4 SV=1 CANONICAL=A0A8V0Z3M8-1" }, "locus": { "chromosome": "23", "start_pos": 5585333, "end_pos": 5582582, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042597.1", "url": "https://www.ensembl.org/id/ENSGALT00010042597.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025087.1", "url": "https://www.ensembl.org/id/ENSGALP00010025087.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:419662", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:419662", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3M8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 114, "start_aa": "Cys", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z3M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M8" }, { "id": "PS50157", "database": "PROSITE", "url": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z458-1", "uniprot_ac": "A0A8V0Z458", "uniprot_id": "A0A8V0Z458_CHICK", "mass": { "chemical_mass": 87844.0, "monoisotopic_mass": 87844.0 }, "refseq": {}, "gene_names": [ { "name": "ECEL1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458" } ] } ], "protein_names": [ { "name": "Endothelin converting enzyme like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z458", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ECEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458", "locus": { "chromosome": "9", "start_pos": 15269759, "end_pos": 15277884, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017702", "url": "https://www.ensembl.org/id/ENSGALG00010017702" } ] } } ], "crossref": [ { "id": "A0A8V0Z458", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z458", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08662", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08662", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YW30", "url": "https://www.orthodb.org/?gene=A0A8V0YW30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z458", "url": "https://www.orthodb.org/?gene=A0A8V0Z458", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Z1", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Z1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11733", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11733", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11733:SF195", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11733:SF195", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05649", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05649", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YW30", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YW30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YW30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z458", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z458-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Z1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKTYSLTAHYDEFQEVKYVSRYQSGTLPNGFALQLGAGTKKRSGGGGLPRWSRREICLLSGLVFAAGLCVILTCMLVLKYLAAEGDSYCLEGCQEKKAFLRASRFLSANMDATIDPCQDFYSFACGGWLRRHGIPEDKLVYGTIGAIAEQNEAKLQALLSRPVRRRAPTSAERKVKEFFRSCLNRAEIDRLGPRPMLEVIGECGGWDASPGSGDLNELLYKTQGVYSAAVLFSLTVSLDDRNTSRYVIRIDQDGLTLPERTLYLGQDEESEKILAAYRVFMERLLTLLGAEHVEQKAQEILQLEQHLANITVSEYDDVRRDVSSMYHKVTLGELQRITPMLKWKRLLDRIFHDNFSEDEEVVLLATDYMHKVSDLIRVTPSRILHNYMLWRIVVVLSEHLSTPFRDAIHELSKEMEGNEKQLELGKVCLSQANKHFGMALGALFVEEYFSSASKAKVQQLVEDIKYILDQRLDELDWMDEETRRAARAKVLQYMMVMIGYPDFLLKPEAIDKEYEFEVDEKTYFKNILNSIAFSIRLSVKKIRQEVDKSVWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPEFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRHGNLVHWWTETSYSKFLKKAQCIVNLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYYAYQKWVREHGPEHPLHHLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRVFHCPKNSPMNPVHKCSVW", "length": 764, "header": "tr|A0A8V0Z458-1|A0A8V0Z458_CHICK Isoform 1 of Endothelin converting enzyme like 1 OS=Gallus gallus OX=9031 GN=ECEL1 PE=4 SV=1 CANONICAL=A0A8V0Z458-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YW30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458/entry#A0A8V0YW30-1", "sequence": { "sequence": "MEKTYSLTAHYDEFQEVKYVSRYQSGTLPNGFALQLGAGTKKRSGGGGLPRWSRREICLLSGLVFAAGLCVILTCMLVLKYLAAEGDSYCLEGCQEKKAFLRASRFLSANMDATIDPCQDFYSFACGGWLRRHGIPEDKLVYGTIGAIAEQNEAKLQALLSRPVRRRAPTSAERKVKEFFRSCLNRAEIDRLGPRPMLEVIGECGGWDASPGSGDLNELLYKTQGVYSAAVLFSLTVSLDDRNTSRYVIRIDQDGLTLPERTLYLGQDEESEKILAAYRVFMERLLTLLGAEHVEQKAQEILQLEQHLANITVSEYDDVRRDVSSMYHKVTLGELQRITPMLKWKRLLDRIFHDNFSEDEEVVLLATDYMHKVSDLIRVTPSRILHNYMLWRIVVVLSEHLSTPFRDAIHELSKEMEGNEKQLELGKVCLSQANKHFGMALGALFVEEYFSSASKAKVQQLVEDIKYILDQRLDELDWMDEETRRAARAKLQYMMVMIGYPDFLLKPEAIDKEYEFEVDEKTYFKNILNSIAFSIRLSVKKIRQEVDKSVSLNYGGIGTIIGHELTHGYDDWGGQYDRHGNLVHWWTETSYSKFLKKAQCIVNLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYYAYQKWVREHGPEHPLHHLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRVFHCPKNSPMNPVHKCSVW", "length": 726, "header": "tr|A0A8V0YW30-1|A0A8V0Z458_CHICK Computationally mapped isoform of Endothelin converting enzyme like 1 OS=Gallus gallus OX=9031 GN=ECEL1 PE=4 SV=1 CANONICAL=A0A8V0Z458-1" }, "locus": { "chromosome": "9", "start_pos": 15276189, "end_pos": 15270163, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042801.1", "url": "https://www.ensembl.org/id/ENSGALT00010042801.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025291.1", "url": "https://www.ensembl.org/id/ENSGALP00010025291.1" } ] } }, { "isoform_ac": "A0A8V0Z458-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458/entry#A0A8V0Z458-1", "sequence": { "sequence": "MEKTYSLTAHYDEFQEVKYVSRYQSGTLPNGFALQLGAGTKKRSGGGGLPRWSRREICLLSGLVFAAGLCVILTCMLVLKYLAAEGDSYCLEGCQEKKAFLRASRFLSANMDATIDPCQDFYSFACGGWLRRHGIPEDKLVYGTIGAIAEQNEAKLQALLSRPVRRRAPTSAERKVKEFFRSCLNRAEIDRLGPRPMLEVIGECGGWDASPGSGDLNELLYKTQGVYSAAVLFSLTVSLDDRNTSRYVIRIDQDGLTLPERTLYLGQDEESEKILAAYRVFMERLLTLLGAEHVEQKAQEILQLEQHLANITVSEYDDVRRDVSSMYHKVTLGELQRITPMLKWKRLLDRIFHDNFSEDEEVVLLATDYMHKVSDLIRVTPSRILHNYMLWRIVVVLSEHLSTPFRDAIHELSKEMEGNEKQLELGKVCLSQANKHFGMALGALFVEEYFSSASKAKVQQLVEDIKYILDQRLDELDWMDEETRRAARAKVLQYMMVMIGYPDFLLKPEAIDKEYEFEVDEKTYFKNILNSIAFSIRLSVKKIRQEVDKSVWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPEFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRHGNLVHWWTETSYSKFLKKAQCIVNLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYYAYQKWVREHGPEHPLHHLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRVFHCPKNSPMNPVHKCSVW", "length": 764, "header": "tr|A0A8V0Z458-1|A0A8V0Z458_CHICK Isoform 1 of Endothelin converting enzyme like 1 OS=Gallus gallus OX=9031 GN=ECEL1 PE=4 SV=1 CANONICAL=A0A8V0Z458-1" }, "locus": { "chromosome": "9", "start_pos": 15276189, "end_pos": 15270163, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042799.1", "url": "https://www.ensembl.org/id/ENSGALT00010042799.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025289.1", "url": "https://www.ensembl.org/id/ENSGALP00010025289.1" } ] } }, { "isoform_ac": "A0A8V0Z9Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458/entry#A0A8V0Z9Z1-1", "sequence": { "sequence": "MEKTYSLTAHYDEFQEVKYVSRYQSGTLPNGFALQLGAGTKKRSGGGGLPRWSRREICLLSGLVFAAGLCVILTCMLVLKYLAAEGDSYCLEGCQEKKAFLRASRFLSANMDATIDPCQDFYSFACGGWLRRHGIPEDKLVYGTIGAIAEQNEAKLQALLSRPVRRRAPTSAERKVKEFFRSCLNRAEIDRLGPRPMLEVIGECGGWDASPGSGDLNELLYKTQGVYSAAVLFSLTVSLDDRNTSRYVIRIDQDGLTLPERTLYLGQDEESEKILAAYRVFMERLLTLLGAEHVEQKAQEILQLEQHLANLKWKRLLDRIFHDNFSEDEEVVLLATDYMHKVSDLIRVTPSRILHNYMLWRIVVVLSEHLSTPFRDAIHELSKEMEGNEKQLELGKVCLSQANKHFGMALGALFVEEYFSSASKAKVQQLVEDIKYILDQRLDELDWMDEETRRAARAKLQYMMVMIGYPDFLLKPEAIDKEYEFEVDEKTYFKNILNSIAFSIRLSVKKIRQEVDKSVWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPEFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRHGNLVHWWTETSYSKFLKKAQCIVNLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYYAYQKWVREHGPEHPLHHLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRVFHCPKNSPMNPVHKCSVW", "length": 732, "header": "tr|A0A8V0Z9Z1-1|A0A8V0Z458_CHICK Computationally mapped isoform of Endothelin converting enzyme like 1 OS=Gallus gallus OX=9031 GN=ECEL1 PE=4 SV=1 CANONICAL=A0A8V0Z458-1" }, "locus": { "chromosome": "9", "start_pos": 15276189, "end_pos": 15270163, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042796.1", "url": "https://www.ensembl.org/id/ENSGALT00010042796.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025286.1", "url": "https://www.ensembl.org/id/ENSGALP00010025286.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z458", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z458", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z458", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458" } ], "pmid": "" }, { "name": "respiratory system process", "id": "GO:0003016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003016", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z458", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458" } ], "pmid": "" }, { "name": "protein processing", "id": "GO:0016485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016485", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z458", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z458", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458" }, { "id": "PF01431", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01431" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M13 C-terminal", "eco_id": "ECO_0000259", "start_pos": 560, "end_pos": 763, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z458" }, { "id": "PF05649", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05649" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M13 N-terminal", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 502, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 645, "end_pos": 647 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4L9-1", "uniprot_ac": "A0A8V0Z4L9", "uniprot_id": "A0A8V0Z4L9_CHICK", "mass": { "chemical_mass": 141815.0, "monoisotopic_mass": 141815.0 }, "refseq": {}, "gene_names": [ { "name": "IGDCC4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9" } ] } ], "protein_names": [ { "name": "Immunoglobulin superfamily DCC subclass member 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IGDCC4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9", "locus": { "chromosome": "10", "start_pos": 17956720, "end_pos": 18036449, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017782", "url": "https://www.ensembl.org/id/ENSGALG00010017782" } ] } } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415537", "url": "https://www.ncbi.nlm.nih.gov/gene/415537", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415537", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415537", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LHWCPPS", "url": "https://omabrowser.org/oma/group/LHWCPPS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWK4", "url": "https://www.orthodb.org/?gene=A0A8V0YWK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4L9", "url": "https://www.orthodb.org/?gene=A0A8V0Z4L9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4M4", "url": "https://www.orthodb.org/?gene=A0A8V0Z4M4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YWK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4M4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSLPGSAAHFCSAAALPCSGCACCTRQVAVWGGFPAFTHSLPPAGRLLEGDSVELSCSAGPAKVILEPNQVVVLDCNLAPAEQVINITWKKNGFPLVEQEHLHVLPNGSLFISSQAVAKDSKYSERADAEGNYSCVSHSSLGAVTSQTAAVRFSTLARFFQQPESQTVEENGMARFECRIEGLPSPVITWEKDHVAVPEEPRFITLPNGVLQIVDVQESDAGVYHCVASNAARKRYSNAAVLSVLKGSQPAGGDVTIIAAPENTTVVAGESVVMECMAAADPTPFVSWIRQDGKPVSTDVIVLGRTNLLIPSSQPHHSGVYVCRANKPQTRQFVTAAAELRVLATPSISQAPETISRTRASTARFVCKAEGEPAPTIHWLKNGEAILSNGRVKVQSSGSLVINQIGLEDAGYYQCVAENSLGMACATAKLSVIVREGLPSAPKKVSAVSLSSTTVLVSWERPEYNSEQIIGFSLHYQRAVGTDNVEYQFAVNNDTTELQVKDLEPNTNYVFYVVAYSQLGASRTSSSIIVQTLEDVPSAAPQLSLSSMTPGDIRVTWLPLPPELSNGKITKYKIDYCTIKEDQVNSIEVGGNETQITLYSLHPNKVYKVRIAASTSVGYGAPSEWTQHRTPDRDNQTHVPFAPTELKVRAKMESLLITWQPPANHAQISGYKLYYREVGQEESSDESPLDGAEEESWDVGPIKLKKKVKQYELTRLAPGKLYEVKLVAFNKHEDGYAAVWKGKTEKAPATAVDPPVQKGPPLPPVQVYAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLKNASLVTYYTSSDEDILISGLKPYTRYEFAVQSNGVGIDGPFGSVVERFTLPDRPSTPPSDLRLHPLNPYAVQVHWCPPAEPNGIIVEYLILYNANNTQPDDMWTLLTREGNIFSTEVHGLESDTRYFFKMGAKTVVGSGPYSNVKDVHTLREKLSDVLDIHSVTGIIVGVCLGLLCILFCMCASFRNSKQREALPGLDSQATGNHTYYHRGRQGAAAPCATSDTHELESLMSPLPEDAPVPLGDITELTEVHSLIHTSLPEDIVHGKRKSSWNKSANQPWTNSIARYGDTITKEPLPAVNGSLKLPSSAGQKLLLQALVYDAVMNEAKKSHPPASLHQVEAEVIVHSDFSASDRDCDSQLHALDGQQTEAEEQEHEEFSPGDLALHSSPSTQQDAHQELMDCSGDVEVQTQDELLYATRKANRTEAVCIPGLTNGFHRNGESLDSVESGDSDSIPEGRADVQPVKSQALSVAPEEAPLCSNSSLTSSSASENIARVHNH", "length": 1304, "header": "tr|A0A8V0Z4L9-1|A0A8V0Z4L9_CHICK Isoform 1 of Immunoglobulin superfamily DCC subclass member 4 OS=Gallus gallus OX=9031 GN=IGDCC4 PE=3 SV=1 CANONICAL=A0A8V0Z4L9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YWK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9/entry#A0A8V0YWK4-1", "sequence": { "sequence": "MRSRRPQLPAPGRAYMALEDLLCVCFAVLAVQGRLLEGDSVELSCSAGPAKVILEPNQVVVLDCNLAPAEQVINITWKKNGFPLVEQEHLHVLPNGSLFISSQAVAKDSKYSERADAEGNYSCVSHSSLGAVTSQTAAVRFSTLARFFQQPESQTVEENGMARFECRIEGLPSPVITWEKDHVAVPEEPRFITLPNGVLQIVDVQESDAGVYHCVASNAARKRYSNAAVLSVLKGSQPAGGDVTIIAAPENTTVVAGESVVMECMAAADPTPFVSWIRQDGKPVSTDVIVLGRTNLLIPSSQPHHSGVYVCRANKPQTRQFVTAAAELRVLATPSISQAPETISRTRASTARFVCKAEGEPAPTIHWLKNGEAILSNGRVKVQSSGSLVINQIGLEDAGYYQCVAENSLGMACATAKLSVIVREGLPSAPKKVSAVSLSSTTVLVSWERPEYNSEQIIGFSLHYQRAVGTDNVEYQFAVNNDTTELQVKDLEPNTNYVFYVVAYSQLGASRTSSSIIVQTLEDVPSAAPQLSLSSMTPGDIRVTWLPLPPELSNGKITKYKIDYCTIKEADQVNSIEVGGNETQITLYSLHPNKVYKVRIAASTSVGYGAPSEWTQHRTPDRDNQTHVPFAPTELKVRAKMESLLITWQPPANHAQISGYKLYYREVGQEESSDESPLDGAEEESWDVGPIKLKKKVKQYELTRLAPGKLYEVKLVAFNKHEDGYAAVWKGKTEKAPATAVDPPVQKGPPLPPVQVYAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLKNASLVTYYTSSDEDILISGLKPYTRYEFAVQSNGVGIDGPFGSVVERFTLPDRPSTPPSDLRLHPLNPYAVQVHWCPPAEPNGIIVEYLILYNANNTQPDDMWTLLTREGNIFSTEVHGLESDTRYFFKMGAKTVVGSGPYSNVKDVHTLREKLSDVLDIHSVTGIIVGVCLGLLCILFCMCASFRNSKQREALPGLDSQATGNHTYYHRGRQGAAAPCATSDTHELESLMSPLPEDAPVPLGDITELTEVHSLIHTSLPEDIVHGKRKSSWNKSANQPWTNSIARYGDTITKEPLPAVNGSLKLPSSAGQKLLLQALVYDAVMNEAKKSHPPASLHQVEAEVIVHSDFSASDRDCDSQLHALDGQQTEAEEQEHEEFSPGDLALHSSPSTQQDAHQELMDCSGDVEVQTQDELLYATRKANRTEAVCIPGLTNGFHRNGESLDSVESGDSDSIPEGRADVQPVKSQALSVAPEEAPLCSNSSLTSSSASENIARVHNH", "length": 1292, "header": "tr|A0A8V0YWK4-1|A0A8V0Z4L9_CHICK Computationally mapped isoform of Immunoglobulin superfamily DCC subclass member 4 OS=Gallus gallus OX=9031 GN=IGDCC4 PE=3 SV=1 CANONICAL=A0A8V0Z4L9-1" }, "locus": { "chromosome": "10", "start_pos": 18036352, "end_pos": 17960488, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042977.1", "url": "https://www.ensembl.org/id/ENSGALT00010042977.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025467.1", "url": "https://www.ensembl.org/id/ENSGALP00010025467.1" } ] } }, { "isoform_ac": "A0A8V0Z4L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9/entry#A0A8V0Z4L9-1", "sequence": { "sequence": "MRSLPGSAAHFCSAAALPCSGCACCTRQVAVWGGFPAFTHSLPPAGRLLEGDSVELSCSAGPAKVILEPNQVVVLDCNLAPAEQVINITWKKNGFPLVEQEHLHVLPNGSLFISSQAVAKDSKYSERADAEGNYSCVSHSSLGAVTSQTAAVRFSTLARFFQQPESQTVEENGMARFECRIEGLPSPVITWEKDHVAVPEEPRFITLPNGVLQIVDVQESDAGVYHCVASNAARKRYSNAAVLSVLKGSQPAGGDVTIIAAPENTTVVAGESVVMECMAAADPTPFVSWIRQDGKPVSTDVIVLGRTNLLIPSSQPHHSGVYVCRANKPQTRQFVTAAAELRVLATPSISQAPETISRTRASTARFVCKAEGEPAPTIHWLKNGEAILSNGRVKVQSSGSLVINQIGLEDAGYYQCVAENSLGMACATAKLSVIVREGLPSAPKKVSAVSLSSTTVLVSWERPEYNSEQIIGFSLHYQRAVGTDNVEYQFAVNNDTTELQVKDLEPNTNYVFYVVAYSQLGASRTSSSIIVQTLEDVPSAAPQLSLSSMTPGDIRVTWLPLPPELSNGKITKYKIDYCTIKEDQVNSIEVGGNETQITLYSLHPNKVYKVRIAASTSVGYGAPSEWTQHRTPDRDNQTHVPFAPTELKVRAKMESLLITWQPPANHAQISGYKLYYREVGQEESSDESPLDGAEEESWDVGPIKLKKKVKQYELTRLAPGKLYEVKLVAFNKHEDGYAAVWKGKTEKAPATAVDPPVQKGPPLPPVQVYAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLKNASLVTYYTSSDEDILISGLKPYTRYEFAVQSNGVGIDGPFGSVVERFTLPDRPSTPPSDLRLHPLNPYAVQVHWCPPAEPNGIIVEYLILYNANNTQPDDMWTLLTREGNIFSTEVHGLESDTRYFFKMGAKTVVGSGPYSNVKDVHTLREKLSDVLDIHSVTGIIVGVCLGLLCILFCMCASFRNSKQREALPGLDSQATGNHTYYHRGRQGAAAPCATSDTHELESLMSPLPEDAPVPLGDITELTEVHSLIHTSLPEDIVHGKRKSSWNKSANQPWTNSIARYGDTITKEPLPAVNGSLKLPSSAGQKLLLQALVYDAVMNEAKKSHPPASLHQVEAEVIVHSDFSASDRDCDSQLHALDGQQTEAEEQEHEEFSPGDLALHSSPSTQQDAHQELMDCSGDVEVQTQDELLYATRKANRTEAVCIPGLTNGFHRNGESLDSVESGDSDSIPEGRADVQPVKSQALSVAPEEAPLCSNSSLTSSSASENIARVHNH", "length": 1304, "header": "tr|A0A8V0Z4L9-1|A0A8V0Z4L9_CHICK Isoform 1 of Immunoglobulin superfamily DCC subclass member 4 OS=Gallus gallus OX=9031 GN=IGDCC4 PE=3 SV=1 CANONICAL=A0A8V0Z4L9-1" }, "locus": { "chromosome": "10", "start_pos": 18013547, "end_pos": 17960488, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042971.1", "url": "https://www.ensembl.org/id/ENSGALT00010042971.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025460.1", "url": "https://www.ensembl.org/id/ENSGALP00010025460.1" } ] } }, { "isoform_ac": "A0A8V0Z4M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9/entry#A0A8V0Z4M4-1", "sequence": { "sequence": "MRSRRPQLPAPGRAYMALEDLLCVCFAVLAVQALARFFQQPESQTVEENGMARFECRIEGLPSPVITWEKDHVAVPEEPRFITLPNGVLQIVDVQESDAGVYHCVASNAARKRYSNAAVLSVLKGSQPAGGDVTIIAAPENTTVVAGESVVMECMAAADPTPFVSWIRQDGKPVSTDVIVLGRTNLLIPSSQPHHSGVYVCRANKPQTRQFVTAAAELRVLATPSISQAPETISRTRASTARFVCKAEGEPAPTIHWLKNGEAILSNGRVKVQSSGSLVINQIGLEDAGYYQCVAENSLGMACATAKLSVIVREGLPSAPKKVSAVSLSSTTVLVSWERPEYNSEQIIGFSLHYQRAVGTDNVEYQFAVNNDTTELQVKDLEPNTNYVFYVVAYSQLGASRTSSSIIVQTLEDVPSAAPQLSLSSMTPGDIRVTWLPLPPELSNGKITKYKIDYCTIKEDQVNSIEVGGNETQITLYSLHPNKVYKVRIAASTSVGYGAPSEWTQHRTPDRDNQTHVPFAPTELKVRAKMESLLITWQPPANHAQISGYKLYYREVGQEESSDESPLDGAEEESWDVGPIKLKKKVKQYELTRLAPGKLYEVKLVAFNKHEDGYAAVWKGKTEKAPATAVDPPVQKGPPLPPVQVYAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLKNASLVTYYTSSDEDILISGLKPYTRYEFAVQSNGVGIDGPFGSVVERFTLPDRPSTPPSDLRLHPLNPYAVQVHWCPPAEPNGIIVEYLILYNANNTQPDDMWTLLTREGNIFSTEVHGLESDTRYFFKMGAKTVVGSGPYSNVKDVHTLREKLSDVLDIHSVTGIIVGVCLGLLCILFCMCASFRNSKQREALPGLDSQATGNHTYYHRGRQGAAAPCATSDTHELESLMSPLPEDAPVPLGDITELTEVHSLIHTSLPEDIVHGKRKSSWNKSANQPWTNSIARYGDTITKEPLPAVNGSLKLPSSAGQKLLLQALVYDAVMNEAKKSHPPASLHQVEAEVIVHSDFSASDRDCDSQLHALDGQQTEAEEQEHEEFSPGDLALHSSPSTQQDAHQELMDCSGDVEVQTQDELLYATRKANRTEAVCIPGLTNGFHRNGESLDSVESGDSDSIPEGRADVQPVKSQALSVAPEEAPLCSNSSLTSSSASENIARVHNH", "length": 1181, "header": "tr|A0A8V0Z4M4-1|A0A8V0Z4M4_CHICK Computationally mapped isoform of Immunoglobulin superfamily DCC subclass member 4 OS=Gallus gallus OX=9031 GN=IGDCC4 PE=3 SV=1 CANONICAL=A0A8V0Z4L9-1" }, "locus": { "chromosome": "10", "start_pos": 18036352, "end_pos": 17960488, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042975.1", "url": "https://www.ensembl.org/id/ENSGALT00010042975.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025465.1", "url": "https://www.ensembl.org/id/ENSGALP00010025465.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415537", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415537", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ASC6-1", "protein_name": "Immunoglobulin superfamily DCC subclass member 4", "gene_name": "Igdcc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARADTGRGLLALTFCLLSARGELPLPQETTVQLSCDEGPLRVVLGPEQAVVLDCTLGAAAAGPPTTVTWSKDGDVVLERDNLHLLPNGSLRLSSPLEPEDSDDEEALSVWKVIEGSYSCLAHGPLGVVASQVAVVKLATLEDFSLHPESQTVEENGTARFECHTEGLPAPIITWEKDQVTVTEEPRLITLPNGVLQILDVQDSDAGSYRCVATNSARQRFSQEALLSVALRGSLEATRGQDVVIVAAPENTTVVSGQSVVLECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLIASAQPRHSGVYVCRANKPRTRDFATAAAELRVLAAPAISQAPEALSRTRASTARFVCRASGEPRPTLHWLHDGAPLRPNGRVKVQGGGGSLVITQIGLQDSGYYQCVAENSAGTACAAAPLAVVVREGLPSAPTRVKATPLSSSAVLVAWERPELHSEQIIGFSLHYQKARGVDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSSPALVHTLDDVPSAAPQLSLSSPNPSDIRVAWLPLPSSLSNGQVVKYKIEYGSGKEEDQVFSTEVPGNETQLTLNSLQPNKVYRVRISAGTGAGYGVPSQWMQHRTPGAHNQSHVPFAPAELKVRAKMESLVVSWQPPPHPTQISGYKLYWREVGTEEEADGDRPPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPTPDLPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFGPWGLRNASLVTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSNNHTQPEHQWTLLTTEGNIFSAEVHGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQETFSDSLDVHSVTGIIVGVCLGLLCLLACMCAGLRRSSHREALPGLSSTATAGNPALYSRARLGPPSVPAAHELESLVHPRPQDWSPPPSDVEDKAKVHSLMGGSVSDCRGHSKRKISWAQAGGPNWAGSWAGCELPQGSGPRPALTRALLPPAGTGQTLLLQALVYDAIKSNGRKKPSPACRNQVEAEVIVHSDFSASKGCPDLHLQDLEPEEALPAEVLPPTAGVVDLSQGADWLGRELEECQPATTGPERLTCLPEAASASCSCSDLQPSSAVEEAPGKGCQPKALCPLEISPSLPRAPVSSAQVP", "length": 1253 }, "evidence": [ { "id": "A0A8V0Z4L9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4L9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MGX7-1", "protein_name": "Immunoglobulin superfamily DCC subclass member 4", "gene_name": "IGDCC4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRGDAGRGSGLIALTFCLLTARGEQPLPQETTVSLSCGAGPLQVILGPEQALVLDCSLGVAATGPPTSVTWSKDGGALPEHKHLRLLPNGSLWLSQLPTVDGTDEADPGASEVIEGSYSCLAHGPLGVMASQAAVVKLATLAGFSLHPESQTVEENGTARFQCQIEGLPTPVITWEKDQVTVPEEPRLITLPNGVLQILDVQEGDAGSYRCVATNSAQQRFSQEALLRVAHRGSLASAGGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLITSAQPRHSGVYVCRANKPRRRDFATAAAELRVLAAPVISQAPEALSRTRASTARFVCRASGEPRPWLRWLHDGAPLRPNGRVKVQGGGGSLVITQIRLQDAGYYQCVAENGAGTACAAAPLAVVVREGLPSAPTRVTATPLSSSAVLVAWERPELHSEQIIGFSLHYQKARGVDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSSPALVHTLDDVPSAAPQLSLSSPNPSDIRVAWLPLPPSLSNGQVVKYKIEYGLGKEDQIFFTEVPGNETQFTLNSLQPSKVYRVRISAGTGAGYGAPSQWMQHRTPSVHNQSHVPFAPTELKVRARMESLVVSWQPPPHPAQISGYKLYWREVGAEEEETDGESPPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPTPDLPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLRNASLVTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSNNHTQPEHQWTLLTTEGNIFSAEVHGLESDTRYFFKMGARTEVGPGPFSGLQDVITLQEKLSDSLDVHSVTGIIVGVCLGLLCLLACMCAGLRRSPHREALPGLSSSATAGNPALYSRARLAPPSPPAVHELESLVHPRPQDWSPPPTDIEDRAEVHSLMGGGASAGRGHSKRKISWAQPGGPSWAGSWAGCELPQAGPMPSLTRALLPPAGTGQTLLLQALVYEAIKGNGRKKPPPACRNQVEAEVIVHSDFSASIGTPDLHLQDLEPEDSLPSEAPDLTSSVVDLGQGEDWLDQEPGGCEQAAPGPDRLTCLPEAASDACPYSDLQSNEALEEAPGNNGQPKAPCPPGASPSLPKAPVPSSST", "length": 1252 }, "evidence": [ { "id": "A0A8V0Z4L9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4L9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8TDY8-1", "protein_name": "Immunoglobulin superfamily DCC subclass member 4", "gene_name": "IGDCC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARGDAGRGRGLLALTFCLLAARGELLLPQETTVELSCGVGPLQVILGPEQAAVLNCSLGAAAAGPPTRVTWSKDGDTLLEHDHLHLLPNGSLWLSQPLAPNGSDESVPEAVGVIEGNYSCLAHGPLGVLASQTAVVKLATLADFSLHPESQTVEENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLIANAQPWHSGVYVCRANKPRTRDFATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQLSLSSPNPSDIRVAWLPLPPSLSNGQVVKYKIEYGLGKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPFAPAELKVQAKMESLVVSWQPPPHPTQISGYKLYWREVGAEEEANGDRLPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFSPWGLRNASLVTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEVHGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQEKLSDSLDMHSVTGIIVGVCLGLLCLLACMCAGLRRSPHRESLPGLSSTATPGNPALYSRARLGPPSPPAAHELESLVHPHPQDWSPPPSDVEDRAEVHSLMGGGVSEGRSHSKRKISWAQPSGLSWAGSWAGCELPQAGPRPALTRALLPPAGTGQTLLLQALVYDAIKGNGRKKSPPACRNQVEAEVIVHSDFSASNGNPDLHLQDLEPEDPLPPEAPDLISGVGDPGQGAAWLDRELGGCELAAPGPDRLTCLPEAASASCSYPDLQPGEVLEETPGDSCQLKSPCPLGASPGLPRSPVSSSA", "length": 1250 }, "evidence": [ { "id": "A0A8V0Z4L9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4L9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQS9-1", "protein_name": "Immunoglobulin superfamily DCC subclass member 4", "gene_name": "Igdcc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARADTGRGLLVLTFCLLSARGELPLPQETTVKLSCDEGPLQVILGPEQAVVLDCTLGATAAGPPTRVTWSKDGDTVLEHENLHLLPNGSLWLSSPLEQEDSDDEEALRIWKVTEGSYSCLAHSPLGVVASQVAVVKLATLEDFSLHPESQIVEENGTARFECHTKGLPAPIITWEKDQVTVPEESRLITLPNGVLQILDVQDSDAGSYRCVATNSARQRFSQEASLTVALRGSLEATRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLIASAQPRHSGVYVCRANKPRTRDFATAAAELRVLAAPAISQAPEALSRTRASTARFVCRASGEPRPALHWLHDGIPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGTACAAAPLAVVVREGLPSAPTRVTATPLSSSSVLVAWERPELHSEQIIGFSLHYQKARGVDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSSPALVHTLDDVPSAAPQLTLSSPNPSDIRVAWLPLPSSLSNGQVLKYKIEYGLGKEDQVFSTEVPGNETQLTLNSLQPNKVYRVRISAGTGAGYGVPSQWMQHRTPGVHNQSHVPFAPAELKVRAKMESLVVSWQPPPHPTQISGYKLYWREVGTEEEADGDRPPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPTPDLPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFGPWGLRNASLVTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSNNHTQPEHQWTLLTTEGNIFSAEVHGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQKTFSDSLDVHAVTGIIVGVCLGLLCLLACMCAGLRRSSHREALPGLSSSGTPGNPALYTRARLGPPSVPAAHELESLVHPRPQDWSPPPSDVEDKAEVHSLMGGSVSDCRGHSKRKISWAQAGGPNWAGSWAGCELPQGSGPRPALTRALLPPAGTGQTLLLQALVYDAIKSNGRKKPSPACRNQVEAEVIVHSDFGASKGCPDLHLQDLEPEEPLTAETLPSTSGAVDLSQGADWLGRELGGCQPTTSGPERLTCLPEAASASCSCSDLQPSTAIEEAPGKSCQPKALCPLTVSPSLPRAPVSSAQVP", "length": 1252 }, "evidence": [ { "id": "A0A8V0Z4L9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4L9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1009, "end_pos": 1011, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1078, "end_pos": 1080, "annotation": "n_glycosylation_sequon" }, { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1105, "end_pos": 1107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1227, "end_pos": 1229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1286, "end_pos": 1288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 794, "end_pos": 796, "annotation": "n_glycosylation_sequon" }, { "start_pos": 806, "end_pos": 808, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" }, { "start_pos": 900, "end_pos": 902, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 442, "end_pos": 536, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z4L9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L9" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 153, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1009, "end_pos": 1011 }, { "start_pos": 1078, "end_pos": 1080 }, { "start_pos": 108, "end_pos": 110 }, { "start_pos": 1105, "end_pos": 1107 }, { "start_pos": 1227, "end_pos": 1229 }, { "start_pos": 1286, "end_pos": 1288 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 636, "end_pos": 638 }, { "start_pos": 773, "end_pos": 775 }, { "start_pos": 794, "end_pos": 796 }, { "start_pos": 806, "end_pos": 808 }, { "start_pos": 87, "end_pos": 89 }, { "start_pos": 900, "end_pos": 902 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3K1-1", "uniprot_ac": "A0A8V0Z3K1", "uniprot_id": "A0A8V0Z3K1_CHICK", "mass": { "chemical_mass": 59918.0, "monoisotopic_mass": 59918.0 }, "refseq": { "ac": "NP_989801", "name": "cyclin-L1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989801" }, "gene_names": [ { "name": "CCNL2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1" } ] }, { "name": "CCNL1", "type": "synonym", "evidence": [ { "id": "NP_989801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989801" } ] }, { "name": "CCNL2", "type": "synonym", "evidence": [ { "id": "NP_989801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989801" } ] } ], "protein_names": [ { "name": "Cyclin L2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1/entry#names_and_taxonomy" } ] }, { "name": "cyclin S", "type": "synonym", "evidence": [ { "id": "NP_989801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989801" } ] }, { "name": "cyclin-L1", "type": "synonym", "evidence": [ { "id": "NP_989801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989801" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ720385.1, SRR13267654.70895.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000329.1. On Sep 23, 2021 this sequence version replaced NP_989801.2.", "evidence": [ { "database": "RefSeq", "id": "NP_989801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989801" } ] }, { "annotation": "Cyclin S gene expression in upregulated in the 1-day-old chick intermediate medial hyperstriatum ventrale, an area that has been correlated with initial processing of memory formation.", "evidence": [ { "database": "RefSeq", "id": "NP_989801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989801" }, { "database": "PubMed", "id": "14725631", "url": "https://glygen.org/publication/PubMed/14725631" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCNL2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1", "locus": { "chromosome": "21", "start_pos": 2216027, "end_pos": 2207499, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017791", "url": "https://www.ensembl.org/id/ENSGALG00010017791" } ] } } ], "crossref": [ { "id": "A0A8V0Z3K1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3K1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395124", "url": "https://www.ncbi.nlm.nih.gov/gene/395124", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:395124", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NYEEVML", "url": "https://omabrowser.org/oma/group/NYEEVML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWM5", "url": "https://www.orthodb.org/?gene=A0A8V0YWM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z319", "url": "https://www.orthodb.org/?gene=A0A8V0Z319", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3K1", "url": "https://www.orthodb.org/?gene=A0A8V0Z3K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_989801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989801", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YWM5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z319", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z319", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z319-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z319-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGSGSAAAVAAVAGGGPAGPHAAGVTAGAVTTGSGAPVPGPGAVLIGDRLYSGVLITLENCLLPEHTLRFTPSMSSGLDPDTETELRVTGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKPVPLILDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGTTEEEIQEICLKILQLYTRKKVDLSDLESKIEKKKLAIEEAKAQAKGLLPEGAPVLDNMSGFSPLPKNESPKEVKGNKPSPLPVQAMKNAKRKAEGAKRTGSNSPVNGVQKGRESRSRSGSRDQSYSRSPSRSASPKHRKSESYSTSSGSKSHSRSRSRSDSPPRQFNHSSTYKSSKMRSYKKSKDYKYSAHKARKSRSRSSSRSRSRSRERSDHSGKYKKKSHYYRNHRHERSRSYERASHRYDRDHPGHSRHRR", "length": 534, "header": "tr|A0A8V0Z3K1-1|A0A8V0Z3K1_CHICK Isoform 1 of Cyclin L2 OS=Gallus gallus OX=9031 GN=CCNL2 PE=3 SV=1 CANONICAL=A0A8V0Z3K1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YWM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1/entry#A0A8V0YWM5-1", "sequence": { "sequence": "MAAGSGSAAAVAAVAGGGPAGPHAAGVTAGAVTTGSGAPVPGPGAVLIGDRLYSGVLITLENCLLPEHTLRFTPSMSSGLDPDTETELRVTGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKPVPLILDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHKVYLVLCNSVILSFRNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGTTEEEIQEICLKILQLYTRKKVDLSDLESKIEKKKLAIEEAKAQAKGLLPEGAPVLDNMSGFSPLPKNESPKEVKGNKPSPLPVQAMKNAKRKAEGAKRTGSNSPVNGVQKGRESRSRSGSRDQSYSRSPSRSASPKHRKSESYSTSSGSKSHSRSRSRSDSPPRQFNHSSTYKSSKMRSYKKSKDYKYSAHKARKSRSRSSSRSRSRSRERSDHSGKYKKKSHYYRNHRHERSRSYERASHRYDRDHPGHSRHRR", "length": 526, "header": "tr|A0A8V0YWM5-1|A0A8V0Z3K1_CHICK Computationally mapped isoform of Cyclin L2 OS=Gallus gallus OX=9031 GN=CCNL2 PE=3 SV=1 CANONICAL=A0A8V0Z3K1-1" }, "locus": { "chromosome": "21", "start_pos": 2215033, "end_pos": 2207593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042997.1", "url": "https://www.ensembl.org/id/ENSGALT00010042997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025487.1", "url": "https://www.ensembl.org/id/ENSGALP00010025487.1" } ] } }, { "isoform_ac": "A0A8V0Z319-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1/entry#A0A8V0Z319-1", "sequence": { "sequence": "MNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGTTEEEIQEICLKILQLYTRKKVDLSDLESKIEKKKLAIEEAKAQAKGLLPEGAPVLDNMSGFSPLPKNESPKEVKGNKPSPLPVQAMKNAKRKAEGAKRTGSNSPVNGVQKGRESRSRSGSRDQSYSRSPSRSASPKHRKSESYSTSSGSKSHSRSRSRSDSPPRQFNHSSTYKSSKMRSYKKSKDYKYSAHKARKSRSRSSSRSRSRSRERSDHSGKYKKKSHYYRNHRHERSRSYERASHRYDRDHPGHSRHRR", "length": 301, "header": "tr|A0A8V0Z319-1|A0A8V0Z319_CHICK Computationally mapped isoform of Cyclin L2 OS=Gallus gallus OX=9031 GN=CCNL2 PE=4 SV=1 CANONICAL=A0A8V0Z3K1-1" }, "locus": { "chromosome": "21", "start_pos": 2215033, "end_pos": 2212926, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042989.1", "url": "https://www.ensembl.org/id/ENSGALT00010042989.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025479.1", "url": "https://www.ensembl.org/id/ENSGALP00010025479.1" } ] } }, { "isoform_ac": "A0A8V0Z3K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1/entry#A0A8V0Z3K1-1", "sequence": { "sequence": "MAAGSGSAAAVAAVAGGGPAGPHAAGVTAGAVTTGSGAPVPGPGAVLIGDRLYSGVLITLENCLLPEHTLRFTPSMSSGLDPDTETELRVTGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKPVPLILDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGTTEEEIQEICLKILQLYTRKKVDLSDLESKIEKKKLAIEEAKAQAKGLLPEGAPVLDNMSGFSPLPKNESPKEVKGNKPSPLPVQAMKNAKRKAEGAKRTGSNSPVNGVQKGRESRSRSGSRDQSYSRSPSRSASPKHRKSESYSTSSGSKSHSRSRSRSDSPPRQFNHSSTYKSSKMRSYKKSKDYKYSAHKARKSRSRSSSRSRSRSRERSDHSGKYKKKSHYYRNHRHERSRSYERASHRYDRDHPGHSRHRR", "length": 534, "header": "tr|A0A8V0Z3K1-1|A0A8V0Z3K1_CHICK Isoform 1 of Cyclin L2 OS=Gallus gallus OX=9031 GN=CCNL2 PE=3 SV=1 CANONICAL=A0A8V0Z3K1-1" }, "locus": { "chromosome": "21", "start_pos": 2215033, "end_pos": 2207593, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042996.1", "url": "https://www.ensembl.org/id/ENSGALT00010042996.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025486.1", "url": "https://www.ensembl.org/id/ENSGALP00010025486.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Cyclin S: a new member of the cyclin family plays a role in long-term memory.", "journal": "The European journal of neuroscience", "date": "2004-01", "authors": "Edelheit Sarit, Meiri Noam", "evidence": [ { "database": "RefSeq", "id": "NP_989801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_989801" } ], "reference": [ { "type": "PubMed", "id": "14725631", "url": "https://glygen.org/publication/PubMed/14725631" } ] } ], "pathway": [ { "id": "gga:395124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:395124", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7JDF3-1", "protein_name": "Cyclin-L2 isoform X2", "gene_name": "Ccnl2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAAAAGASVLAAPALAAGSSGSGGAAPGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLDIDTETGLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKPVPLVLDQEYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTAWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICFKILQLYTRKKVDLTHLESEVEKRKHAIDEAKARARGLLPGSAPILDSAAGFSPAPKLVESPKEGKGNKSSPLSVKNAKRKVEGPKKAKTDSPVNGLPKGHESRSQSRSREQSYSRSPSRSASPKRRKSESGSTSGGSKSQSRSRSRSDSPPRQVHRGAPYKGSEVRTSRKSKDCKYLTQKPHKSRSRSSSRSRSRSRERTDNSGKYKKKSHYYRDQRRERSRSYERTGHRYERDHPGHSRHRR", "length": 519 }, "evidence": [ { "id": "A0A8V0Z3K1", "url": "https://omabrowser.org/oma/group/A0A8V0Z3K1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1MIJ6-1", "protein_name": "Cyclin L2", "gene_name": "CCNL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAAGAGAPGSTAPAVPAGTPGSGGTAPASQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRHLREKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICLKILQLYTRKKVDLTHLESEVEKRRHALDEAKAQAKGLLPGSTQVLDSASRFSPAPKPVESPKEGKGNKPSPLSVKNTKRKVEGVKKTKADSPVNGLPKEQGSRSRSGSHEQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAHRGAPYKGSKVRSYRRSKDCKYSTQKPHKSRSRSSSRSRSRSRERADTSGKYKKKSHYYREQRRERSRSYERTGHRYERDHPGHSRHRR", "length": 520 }, "evidence": [ { "id": "A0A8V0Z3K1", "url": "https://omabrowser.org/oma/group/A0A8V0Z3K1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96S94-1", "protein_name": "Cyclin-L2", "gene_name": "CCNL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAAAAGAAGSAAPAAAAGAPGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDKLRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLECERNQHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPLPNRPHWFLLFGATEEEIQEICLKILQLYARKKVDLTHLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNTKRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSRSRSDSPPRQAPRSAPYKGSEIRGSRKSKDCKYPQKPHKSRSRSSSRSRSRSRERADNPGKYKKKSHYYRDQRRERSRSYERTGRRYERDHPGHSRHRR", "length": 520 }, "evidence": [ { "id": "A0A8V0Z3K1", "url": "https://omabrowser.org/oma/group/A0A8V0Z3K1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1" } ], "pmid": "" }, { "name": "cyclin L-CDK11 complex", "id": "GO:0180038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0180038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1" }, { "id": "SM01332", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01332" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin C-terminal", "eco_id": "ECO_0000259", "start_pos": 205, "end_pos": 328, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z3K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K1" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 196, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 235, "end_pos": 237 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 446, "end_pos": 448 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3T5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4W9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAR9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWVQVVANRSNEDIFDEDADEMYPVQKEWNNTMRKRLKEGYRDGVEAGKELALQEGFNQGYRQGAELMVACGQFRGTLNALLSWCHLNGHDSALRKINNLLEVIGKHEEDLLKCLNSVQLQPNVGDILDSIQDMDLSHIAPAGVDCSEVKAEKYGHVGSSDENCCRNNGEDGSLQFDCNREKLFTDPDKSTLAWVKKQTLWLVEQLGLSLDILHHIQQLEH", "length": 222, "header": "tr|A0A8V0Z4W9-1|A0A8V0Z4W9_CHICK Isoform 1 of YAE1 maturation factor of ABCE1 OS=Gallus gallus OX=9031 GN=YAE1D1 PE=4 SV=1 CANONICAL=A0A8V0Z4W9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YWW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W9/entry#A0A8V0YWW0-1", "sequence": { "sequence": "MSWVQVVANRSNEDIFDEDADEMYPVQKEWNNTMRKRLKEGYRDGVEAGKELALQEGFNQGYRQGAELMVACGQFRGTLNL", "length": 81, "header": "tr|A0A8V0YWW0-1|A0A8V0Z4W9_CHICK Computationally mapped isoform of YAE1 maturation factor of ABCE1 OS=Gallus gallus OX=9031 GN=YAE1D1 PE=4 SV=1 CANONICAL=A0A8V0Z4W9-1" }, "locus": { "chromosome": "2", "start_pos": 49814298, "end_pos": 49812483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043078.1", "url": "https://www.ensembl.org/id/ENSGALT00010043078.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025568.1", "url": "https://www.ensembl.org/id/ENSGALP00010025568.1" } ] } }, { "isoform_ac": "A0A8V0Z3T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W9/entry#A0A8V0Z3T5-1", "sequence": { "sequence": "MSWVQVVANRSNEDIFDEDADEMYPVQKEWNNTMRKRLKEGYRDGVEAGKELALQEGFNQGYRQGAELMVACGQFRGTLKLGKKEMAERK", "length": 90, "header": "tr|A0A8V0Z3T5-1|A0A8V0Z3T5_CHICK Computationally mapped isoform of YAE1 maturation factor of ABCE1 OS=Gallus gallus OX=9031 GN=YAE1D1 PE=4 SV=1 CANONICAL=A0A8V0Z4W9-1" }, "locus": { "chromosome": "2", "start_pos": 49841587, "end_pos": 49812483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043087.1", "url": "https://www.ensembl.org/id/ENSGALT00010043087.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025577.1", "url": "https://www.ensembl.org/id/ENSGALP00010025577.1" } ] } }, { "isoform_ac": "A0A8V0Z4W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W9/entry#A0A8V0Z4W9-1", "sequence": { "sequence": "MSWVQVVANRSNEDIFDEDADEMYPVQKEWNNTMRKRLKEGYRDGVEAGKELALQEGFNQGYRQGAELMVACGQFRGTLNALLSWCHLNGHDSALRKINNLLEVIGKHEEDLLKCLNSVQLQPNVGDILDSIQDMDLSHIAPAGVDCSEVKAEKYGHVGSSDENCCRNNGEDGSLQFDCNREKLFTDPDKSTLAWVKKQTLWLVEQLGLSLDILHHIQQLEH", "length": 222, "header": "tr|A0A8V0Z4W9-1|A0A8V0Z4W9_CHICK Isoform 1 of YAE1 maturation factor of ABCE1 OS=Gallus gallus OX=9031 GN=YAE1D1 PE=4 SV=1 CANONICAL=A0A8V0Z4W9-1" }, "locus": { "chromosome": "2", "start_pos": 49817350, "end_pos": 49812483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043081.1", "url": "https://www.ensembl.org/id/ENSGALT00010043081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025571.1", "url": "https://www.ensembl.org/id/ENSGALP00010025571.1" } ] } }, { "isoform_ac": "A0A8V0ZAR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W9/entry#A0A8V0ZAR9-1", "sequence": { "sequence": "MSWVQVVANRSNEDIFDEDADEMYPVQKEWNNTMRKRLKEGYRDGVEAGKELALQEGFNQGYRQGAELMVACGQFRGTLKVVLHVYAY", "length": 88, "header": "tr|A0A8V0ZAR9-1|A0A8V0Z4W9_CHICK Computationally mapped isoform of YAE1 maturation factor of ABCE1 OS=Gallus gallus OX=9031 GN=YAE1D1 PE=4 SV=1 CANONICAL=A0A8V0Z4W9-1" }, "locus": { "chromosome": "2", "start_pos": 49823116, "end_pos": 49812483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043084.1", "url": "https://www.ensembl.org/id/ENSGALT00010043084.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025574.1", "url": "https://www.ensembl.org/id/ENSGALP00010025574.1" } ] } }, { "isoform_ac": "A0A8V0ZAS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W9/entry#A0A8V0ZAS1-1", "sequence": { "sequence": "MSWVQVVANRSNEDIFDEDADEMYPVQKEWNNTMRKRLKEGYRDGVEAGKELALQEGFNQGYRQGAELMVACGQFRGTLKGTTEQLYGAETPARLNHNTGFALLRRNVRLGKKEMAERK", "length": 119, "header": "tr|A0A8V0ZAS1-1|A0A8V0Z4W9_CHICK Computationally mapped isoform of YAE1 maturation factor of ABCE1 OS=Gallus gallus OX=9031 GN=YAE1D1 PE=4 SV=1 CANONICAL=A0A8V0Z4W9-1" }, "locus": { "chromosome": "2", "start_pos": 49841587, "end_pos": 49812483, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043089.1", "url": "https://www.ensembl.org/id/ENSGALT00010043089.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025579.1", "url": "https://www.ensembl.org/id/ENSGALP00010025579.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420764", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420764", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061I7H1-1", "protein_name": "Protein YAE1 homolog", "gene_name": "Yae1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSWVRAVPEIPSSGDQDVFDEEADETLLVQREWQGHMRRRIQEGYRDGIDAGKAVTLQQGFNQGYKEGAEVIINYGLLRGTLSALLSWCHLHGNSSTLVSKINNLLDAVGQCEECVLKRLKSVAPQPQVTDLLDSIEDMDLCHVVPAEKKIDEVKDERLCENSAEFNKNSDKSHIRTDCSHSECCRTQEHEHLEKPSLTWILEQTASLVKQLGVSVDVLQHLRQL", "length": 225 }, "evidence": [ { "id": "A0A8V0Z4W9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4W9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4AEK7-1", "protein_name": "YAE1 maturation factor of ABCE1", "gene_name": "Yae1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWFRATPEIPSPGDQDVFDEEADESLLVQREWQDHMRKRVQEGYRDGIDAGKAVTLQQGFNQGYKEGADVILNYGLLRGTLSALLSWCHLHGNSSTLIGKINNLLDAVGQCEECVIKHLKSVTSPPHITDLLDSIEDLDLCHVVPPEKAVEARGDTSADISTDADRSPNGMDCSHPECCRTQEHAHLEKPSLTWILEQTSNLVKQLGISVDILQHLRQL", "length": 220 }, "evidence": [ { "id": "A0A8V0Z4W9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4W9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NRH1-1", "protein_name": "Protein YAE1 homolog", "gene_name": "YAE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSWVQAASLIQGPGDKGDVFDEEADESLLAQREWQSNMQRRVKEGYRDGIDAGKAVTLQQGFNQGYKKGAEVILNYGRLRGTLSALLSWCHLHNNNSTLINKINNLLDAVGQCEEYVLKHLKSITPPSHVVDLLDSIEDMDLCHVVPAEKKIDEAKDERLCENNAEFNKNCSKSHSGIDCSYVECCRTQEHAHSENPSPTWILEQTASLVKQLGLSVDVLQHLKQL", "length": 226 }, "evidence": [ { "id": "A0A8V0Z4W9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4W9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4W9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4W9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4W9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W9" }, { "id": "PF09811", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09811" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Essential protein Yae1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 79, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 31, "end_pos": 33 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3H2-1", "uniprot_ac": "A0A8V0Z3H2", "uniprot_id": "A0A8V0Z3H2_CHICK", "mass": { "chemical_mass": 43341.0, "monoisotopic_mass": 43341.0 }, "refseq": { "ac": "XP_015139394", "name": "F-box only protein 28 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139394" }, "gene_names": [ { "name": "FBXO28", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2" } ] }, { "name": "FBXO28", "type": "synonym", "evidence": [ { "id": "XP_015139394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139394" } ] } ], "protein_names": [ { "name": "F-box only protein 28 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015139394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139394" } ] }, { "name": "F-box protein 28", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015139394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139394" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FBXO28", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2", "locus": { "chromosome": "3", "start_pos": 17304947, "end_pos": 17318939, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016589", "url": "https://www.ensembl.org/id/ENSGALG00010016589" } ] } } ], "crossref": [ { "id": "A0A8V0Z3H2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3H2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22100", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22100", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "421328", "url": "https://www.ncbi.nlm.nih.gov/gene/421328", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421328", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421328", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SSHFPRC", "url": "https://omabrowser.org/oma/group/SSHFPRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YWY4", "url": "https://www.orthodb.org/?gene=A0A8V0YWY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3H2", "url": "https://www.orthodb.org/?gene=A0A8V0Z3H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13252:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13252:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015139394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015139394", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YWY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YWY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YWY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAEERLLSEGEGGAPGSARLSPPPLSQSPEAPAPLEQPPQSNTLMGLPIVAIESILSFLSYDETSQLRLVCKRMDLVCQRMLNQGFLKVERYHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLIGAAPGILIKTTFPSSNSSMILGLRKNEYTSSWKINPLLLKIPGPSAALTTMQLFSKQNPSRQEVTKLQQQVKANGAGVTVLKREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAELERKLREVMESAVGSSSGSGSNEQSPRKRRKAVESTDCPRKSKRLRNRK", "length": 386, "header": "tr|A0A8V0Z3H2-1|A0A8V0Z3H2_CHICK Isoform 1 of F-box protein 28 OS=Gallus gallus OX=9031 GN=FBXO28 PE=4 SV=1 CANONICAL=A0A8V0Z3H2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YWY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2/entry#A0A8V0YWY4-1", "sequence": { "sequence": "MAAAEERLLSEGEGGAPGSARLSPPPLSQSPEAPAPLEQPPQSNTLMGLPIVAIESILSFLSYDETSQLRLVCKRMDLVCQRMLNQGFLKVERYHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLIGAAPVPGPSAALTTMQLFSKQNPSRQEVTKLQQQVKANGAGVTVLKREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAELERKLREVMESAVGSSSGSGSNEQSPRKRRKAVESTDCPRKSKRLRNRK", "length": 350, "header": "tr|A0A8V0YWY4-1|A0A8V0Z3H2_CHICK Computationally mapped isoform of F-box protein 28 OS=Gallus gallus OX=9031 GN=FBXO28 PE=4 SV=1 CANONICAL=A0A8V0Z3H2-1" }, "locus": { "chromosome": "3", "start_pos": 17318906, "end_pos": 17307567, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039970.1", "url": "https://www.ensembl.org/id/ENSGALT00010039970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023145.1", "url": "https://www.ensembl.org/id/ENSGALP00010023145.1" } ] } }, { "isoform_ac": "A0A8V0Z3H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2/entry#A0A8V0Z3H2-1", "sequence": { "sequence": "MAAAEERLLSEGEGGAPGSARLSPPPLSQSPEAPAPLEQPPQSNTLMGLPIVAIESILSFLSYDETSQLRLVCKRMDLVCQRMLNQGFLKVERYHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLIGAAPGILIKTTFPSSNSSMILGLRKNEYTSSWKINPLLLKIPGPSAALTTMQLFSKQNPSRQEVTKLQQQVKANGAGVTVLKREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAELERKLREVMESAVGSSSGSGSNEQSPRKRRKAVESTDCPRKSKRLRNRK", "length": 386, "header": "tr|A0A8V0Z3H2-1|A0A8V0Z3H2_CHICK Isoform 1 of F-box protein 28 OS=Gallus gallus OX=9031 GN=FBXO28 PE=4 SV=1 CANONICAL=A0A8V0Z3H2-1" }, "locus": { "chromosome": "3", "start_pos": 17318906, "end_pos": 17307567, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039967.1", "url": "https://www.ensembl.org/id/ENSGALT00010039967.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023142.1", "url": "https://www.ensembl.org/id/ENSGALP00010023142.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421328", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421328", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RZ28-1", "protein_name": "F-box protein 28", "gene_name": "Fbxo28", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAASEERMAEEGGGGHGDGGSCSAASSAQRQPPTPPSQALQPGSQAPAAPALAPDHLPQNNTLVALPIVAIENILSFMSYDEISQLRLVCKRMDLVCQRMLNQGFLKVERYHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLMGSPPVPGPSAALTTMQLFSKQNPSRQEVTKLQQQVKTNGAGVTVLRREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAELERKLREVMESAVGTSSGSGQSEESPRKRRKATEAIDSLRKSKRLRNRK", "length": 368 }, "evidence": [ { "id": "A0A8V0Z3H2", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2NL16-1", "protein_name": "F-box only protein 28", "gene_name": "FBXO28", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAASEERMAEEGGGGHGDGGSPSAIASTQRLPPPPPPQPPQPGSQAPPAPALAPDQLPQNNTLVALPIVAIENILSFMSYDEISQLRLVCKRMDLVCQRMLNQGFLKVERYHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLMGSPPVPGPSAALTTMQLFSKQNPSRQEVTKLQQQVKTNGAGVTVLRREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAELERKLREVMESAVGNSSGSGQSEESPRKRKKAAEAIDSLRKSKRLRNRK", "length": 368 }, "evidence": [ { "id": "A0A8V0Z3H2", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BIG4-1", "protein_name": "F-box only protein 28", "gene_name": "Fbxo28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAASEERMAEEGGGGHGDGGSCSAAGSAQRQPPAPPSQAPPPGSQAPAAPALAPDHLPQNNTLVALPIVAIENILSFMSYDEISQLRLVCKRMDLVCQRMLNQGFLKVERFHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLMGSPPVPGPSAALTTMQLFSKQNPSRQEVTKLQQQVRTNGAGVTVLRREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAELERKLREVMESAVGTSSGSGQSEESPRKRRKATEAIDSLRKSKRLRNRK", "length": 368 }, "evidence": [ { "id": "A0A8V0Z3H2", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVF7-1", "protein_name": "F-box only protein 28", "gene_name": "FBXO28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAEERMAEEGGGGQGDGGSSLASGSTQRQPPPPAPQHPQPGSQALPAPALAPDQLPQNNTLVALPIVAIENILSFMSYDEISQLRLVCKRMDLVCQRMLNQGFLKVERYHNLCQKQVKAQLPRRESERRNHSLARHADILAAVETRLSLLNMTFMKYVDSNLCCFIPGKVIDEIYRVLRYVNSTRAPQRAHEVLQELRDISSMAMEYFDEKIVPILKRKLPGSDVSGRLMGSPPVPGPSAALTTMQLFSKQNPSRQEVTKLQQQVKTNGAGVTVLRREISELRTKVQEQQKQLQDQDQKLLEQTQIIGEQNARLAELERKLREVMESAVGNSSGSGQNEESPRKRKKATEAIDSLRKSKRLRNRK", "length": 368 }, "evidence": [ { "id": "A0A8V0Z3H2", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2" } ], "pmid": "" }, { "name": "kinetochore", "id": "GO:0000776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H2" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 91, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 231, "end_pos": 233 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3K3-1", "uniprot_ac": "A0A8V0Z3K3", "uniprot_id": "A0A8V0Z3K3_CHICK", "mass": { "chemical_mass": 84397.0, "monoisotopic_mass": 84397.0 }, "refseq": {}, "gene_names": [ { "name": "CLCNKB", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3" } ] } ], "protein_names": [ { "name": "Chloride voltage-gated channel Kb", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLCNKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z3K3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3K3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03683", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03683", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04591", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04591", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX02", "url": "https://www.orthodb.org/?gene=A0A8V0YX02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYI6", "url": "https://www.orthodb.org/?gene=A0A8V0YYI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3K3", "url": "https://www.orthodb.org/?gene=A0A8V0Z3K3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45720", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45720", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45720:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45720:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00654", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00654", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2672351", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YX02", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYI6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQADLTPVPRHLPGKPICSWGRAKLPKSSMGQAGDEERLCWWKLCSDRKAEEDFKFIHSRAVLAQPAASSGAAPDPQTSPGMEHPSLEQEEEKVLVSKHSWQPCPKARRRLRGCMEVVKGLLFRVGEDWYFLFVLGVLMATISFMMDLIVFRLYEAHRWLYQEVGDYLVLKYLSWTIYPVALAAFSTGFANSITPHSGGSGIPELKTILSGVELEEYLAIKNFGAKVVGLTCTLSAGSTVFLGKLGPFVHLSSMAAAYLGKMRTAVIREYEDKFKQNEMLVAAQAVGVATVFGAPISGVLFSIEVMSSHFAVRDYWRGFFAATCGAFMFRLLAVFNSEQETIAALFKSNLKIDFPFDLPETFFFVILGAICGAIACAYLFCQRWLLAAVKENRLTGRLLATDKPLYTVLVVLLLASITFPPGLGQLMASRLSMKEHLISLFDNRSWFVLAQNASMAATQLGDPRGLWQEWCHPSATIFGTLVFFLLMKFWMLTLATTLPMPAGYFMPVFIYGAAIGRLQGEVLASLFPHGIHAEGAAYPIVPGGYALAGAAAFSGAVTYSVSTALLVCEATGHMAHVLPVVLAVLVANAITQKCQPSFYDGTIIVKKLPYLPRIRSRHIASYRVVVKEFMEQQVVAVAKGDGFEEVLAALNATTDKEYAVIESKESPMLVGTISRAKLIAFLQSHEHPQAPPGPLQEKPASTGTLGEDCAIEPIVLQLSPWTSLHQAHHLFELLKLQHIFVTHYGKLVGAVTRTELRRAIEELAKEA", "length": 768, "header": "tr|A0A8V0Z3K3-1|A0A8V0Z3K3_CHICK Isoform 1 of Chloride voltage-gated channel Kb OS=Gallus gallus OX=9031 GN=CLCNKB PE=4 SV=1 CANONICAL=A0A8V0Z3K3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YX02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3/entry#A0A8V0YX02-1", "sequence": { "sequence": "MEHPSLEQEEEKVLVSKHSWQPCPKARRRLRGCMEVVKGLLFRVGEDWYFLFVLGVLMATISFMMDLIVFRLYEAHRWLYQEVGDYLVLKYLSWTIYPVALAAFSTGFANSITPHSGGSGIPELKTILSGVELEEYLAIKNFGAKVVGLTCTLSAGSTVFLGKLGPFVHLSSMAAAYLGKMRTAVIREYEDKFKQNEMLVAAQAVGVATVFGAPISGVLFSIEVMSSHFAVRDYWRGFFAATCGAFMFRLLAVFNSEQETIAALFKSNLKIDFPFDLPETFFFVILGAICGAIACAYLFCQRWLLAAVKENRLTGRLLATDKPLYTVLVVLLLASITFPPGLGQLMASRPHTTACCPHSHLLCAPQFWMLTLATTLPMPAGYFMPVFIYGAAIGRLQGEVLASLFPHGIHAEGAAYPIVPGGYALAGAAAFSGAVTYSVSTALLVCEATGHMAHVLPVVLAVLVANAITQKCQPSFYDGTIIVKKLPYLPRIRSRHIASYRVVVKEFMEQQVVAVAKGDGFEEVLAALNATTDKEYAVIESKESPMLVGTISRAKLIAFLQSHEHPQAPPGPLQEKPASTGTLGEDCAIEPIVLQLSPWTSLHQAHHLFELLKLQHIFVTHYGKLVGAVTRTELRRAIEELAKEA", "length": 645, "header": "tr|A0A8V0YX02-1|A0A8V0Z3K3_CHICK Computationally mapped isoform of Chloride voltage-gated channel Kb OS=Gallus gallus OX=9031 GN=CLCNKB PE=4 SV=1 CANONICAL=A0A8V0Z3K3-1" }, "locus": { "chromosome": "21", "start_pos": 4313391, "end_pos": 4309102, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040000.1", "url": "https://www.ensembl.org/id/ENSGALT00010040000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023167.1", "url": "https://www.ensembl.org/id/ENSGALP00010023167.1" } ] } }, { "isoform_ac": "A0A8V0YYI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3/entry#A0A8V0YYI6-1", "sequence": { "sequence": "MEHPSLEQEEEKVLVSKHSWQPCPKARRRLRGCMEVVKGLLFRVGEDWYFLFVLGVLMATISFMMDLIVFRLYEAHRWLYQEVGDYLVLKYLSWTIYPVALAAFSTGFANSITPHSGGSGIPELKTILSGVELEEYLAIKNFGAKVVGLTCTLSAGSTVFLGKLGPFVHLSSMAAAYLGKMRTAVIREYEDKFKQNEMLVAAQAVGVATVFGAPISGVLFSIEVMSSHFAVRDYWRGFFAATCGAFMFRLLAVFNSEQETIAALFKSNLKIDFPFDLPETFFFVILGKPLYTVLVVLLLASITFPPGLGQLMASRLSMKEHLISLFDNRSWFVLAQNASMAATQLGDPRGLWQEWCHPSATIFGTLVFFLLMKFWMLTLATTLPMPAGYFMPVFIYGAAIGRLQGEVLASLFPHGIHAEGAAYPIVPGGYALAGAAAFSGAVTYSVSTALLVCEATGHMAHVLPVVLAVLVANAITQKCQPSFYDGTIIVKKLPYLPRIRSRHIASYRVVVKEFMEQQVVAVAKGDGFEEVLAALNATTDKEYAVIESKESPMLVGTISRAKLIAFLQSHEHPQAPPGPLQEKPASTGTLGEDCAIEPIVLQLSPWTSLHQAHHLFELLKLQHIFVTHYGKLVGAVTRTELRRAIEELAKEA", "length": 652, "header": "tr|A0A8V0YYI6-1|A0A8V0Z3K3_CHICK Computationally mapped isoform of Chloride voltage-gated channel Kb OS=Gallus gallus OX=9031 GN=CLCNKB PE=4 SV=1 CANONICAL=A0A8V0Z3K3-1" }, "locus": { "chromosome": "21", "start_pos": 4313391, "end_pos": 4309102, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039999.1", "url": "https://www.ensembl.org/id/ENSGALT00010039999.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023166.1", "url": "https://www.ensembl.org/id/ENSGALP00010023166.1" } ] } }, { "isoform_ac": "A0A8V0Z3K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3/entry#A0A8V0Z3K3-1", "sequence": { "sequence": "MGQADLTPVPRHLPGKPICSWGRAKLPKSSMGQAGDEERLCWWKLCSDRKAEEDFKFIHSRAVLAQPAASSGAAPDPQTSPGMEHPSLEQEEEKVLVSKHSWQPCPKARRRLRGCMEVVKGLLFRVGEDWYFLFVLGVLMATISFMMDLIVFRLYEAHRWLYQEVGDYLVLKYLSWTIYPVALAAFSTGFANSITPHSGGSGIPELKTILSGVELEEYLAIKNFGAKVVGLTCTLSAGSTVFLGKLGPFVHLSSMAAAYLGKMRTAVIREYEDKFKQNEMLVAAQAVGVATVFGAPISGVLFSIEVMSSHFAVRDYWRGFFAATCGAFMFRLLAVFNSEQETIAALFKSNLKIDFPFDLPETFFFVILGAICGAIACAYLFCQRWLLAAVKENRLTGRLLATDKPLYTVLVVLLLASITFPPGLGQLMASRLSMKEHLISLFDNRSWFVLAQNASMAATQLGDPRGLWQEWCHPSATIFGTLVFFLLMKFWMLTLATTLPMPAGYFMPVFIYGAAIGRLQGEVLASLFPHGIHAEGAAYPIVPGGYALAGAAAFSGAVTYSVSTALLVCEATGHMAHVLPVVLAVLVANAITQKCQPSFYDGTIIVKKLPYLPRIRSRHIASYRVVVKEFMEQQVVAVAKGDGFEEVLAALNATTDKEYAVIESKESPMLVGTISRAKLIAFLQSHEHPQAPPGPLQEKPASTGTLGEDCAIEPIVLQLSPWTSLHQAHHLFELLKLQHIFVTHYGKLVGAVTRTELRRAIEELAKEA", "length": 768, "header": "tr|A0A8V0Z3K3-1|A0A8V0Z3K3_CHICK Isoform 1 of Chloride voltage-gated channel Kb OS=Gallus gallus OX=9031 GN=CLCNKB PE=4 SV=1 CANONICAL=A0A8V0Z3K3-1" }, "locus": { "chromosome": "21", "start_pos": 4313391, "end_pos": 4306113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040005.1", "url": "https://www.ensembl.org/id/ENSGALT00010040005.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023169.1", "url": "https://www.ensembl.org/id/ENSGALP00010023169.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2672351", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2672351", "resource": "Reactome", "description": "Stimuli-sensing channels" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3" } ], "pmid": "" }, { "name": "voltage-gated chloride channel activity", "id": "GO:0005247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005247", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "chloride transport", "id": "GO:0006821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006821", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K3" }, { "id": "PF00571", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00571" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CBS", "eco_id": "ECO_0000259", "start_pos": 723, "end_pos": 762, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 444, "end_pos": 446 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 652, "end_pos": 654 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z432-1", "uniprot_ac": "A0A8V0Z432", "uniprot_id": "A0A8V0Z432_CHICK", "mass": { "chemical_mass": 96098.0, "monoisotopic_mass": 96098.0 }, "refseq": { "ac": "XP_025007365", "name": "exocyst complex component 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007365" }, "gene_names": [ { "name": "EXOC6", "type": "recommended", "evidence": [ { "id": "A0A8V0Z432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432" } ] }, { "name": "EXOC6", "type": "synonym", "evidence": [ { "id": "XP_025007365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007365" } ] }, { "name": "SEC15L1", "type": "synonym", "evidence": [ { "id": "XP_025007365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007365" } ] } ], "protein_names": [ { "name": "Exocyst complex component", "type": "recommended", "evidence": [ { "id": "A0A8V0Z432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432/entry#names_and_taxonomy" } ] }, { "name": "exocyst complex component 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025007365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007365" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025007365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007365" } ] }, { "annotation": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YX44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX44#function" }, { "database": "UniProtKB", "id": "PIRNR025007", "url": "https://www.uniprot.org/uniprotkb/PIRNR025007#function" }, { "database": "UniProtKB", "id": "A0A8V0YX49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX49#function" }, { "database": "UniProtKB", "id": "A0A8V0YX53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX53#function" }, { "database": "UniProtKB", "id": "A0A8V0Z436", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z436#function" }, { "database": "UniProtKB", "id": "A0A8V0Z3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z8#function" }, { "database": "UniProtKB", "id": "A0A8V0ZB11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB11#function" }, { "database": "UniProtKB", "id": "A0A8V0Z432", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432#function" }, { "database": "UniProtKB", "id": "A0A8V0Z555", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z555#function" }, { "database": "UniProtKB", "id": "A0A8V0ZB06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB06#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z432", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EXOC6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432", "locus": { "chromosome": "6", "start_pos": 21370119, "end_pos": 21456896, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017859", "url": "https://www.ensembl.org/id/ENSGALG00010017859" } ] } } ], "crossref": [ { "id": "A0A8V0Z432", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z432", "database": "AlphaFoldDB", "categories": [] }, { "id": "423807", "url": "https://www.ncbi.nlm.nih.gov/gene/423807", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FPFHSEQ", "url": "https://omabrowser.org/oma/group/FPFHSEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX34", "url": "https://www.orthodb.org/?gene=A0A8V0YX34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX44", "url": "https://www.orthodb.org/?gene=A0A8V0YX44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX49", "url": "https://www.orthodb.org/?gene=A0A8V0YX49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX53", "url": "https://www.orthodb.org/?gene=A0A8V0YX53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3Z8", "url": "https://www.orthodb.org/?gene=A0A8V0Z3Z8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z432", "url": "https://www.orthodb.org/?gene=A0A8V0Z432", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z436", "url": "https://www.orthodb.org/?gene=A0A8V0Z436", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z555", "url": "https://www.orthodb.org/?gene=A0A8V0Z555", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB06", "url": "https://www.orthodb.org/?gene=A0A8V0ZB06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB11", "url": "https://www.orthodb.org/?gene=A0A8V0ZB11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12702", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12702", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12702:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12702:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04091", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04091", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-264876", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264876", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5620916", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025007365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025007365", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YX34", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX44", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX49", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX53", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z432", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z432-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z436", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z436", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z436-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z436-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z555", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z555", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z555-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z555-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB06", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB11", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARKSRPNMSEMYLEENKDQIYENALAEIESFELPLGTTLRSVYDDQPNAHQRFMEKLDACIRNHDREIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRLQDAGKEVIAQTEEIIRCRVQQRNITTVVEKLQLCLPVLEMYSKLKEQMKVKRYYSALKTMEQLENLYLPRVSQYRFCQIMIENLPKLREEIKEISMSDLKDFLESIRKHSDRIGETAMKQAQQQKTFSTTLQKHHNVNYGRNMHLGRSRILESRNEMTLKRTFEEDDEHDEEVLTAQDLVDFSPVYRCLHIYSVLGDGEIFENYYRKQRRKQARLVLQPQSSMHETVEGYRRYFSQIVGFFVVEDHILHVTQGLVTRTYTDELWNMALSKIIAVLRTHSSYCNDPDLVLELKNLIVVFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWSGLFRDIFEADNYSPIPVANEEEYKIVISKFPFQDSELDKQCFPKKLPMSQSVPQIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLQNLIKKPHIGLTELVQIIINTTHLELACKYLEDFISNITNISQVTVHTARLYGLSTFKDARHAAEGEIYTKLNQKIDEFIQIADYDWTMSESDGRASGYLMDLINFLRSTFQVFTHLPNNNNDHAAMSGKVAQTACMSACQHLSTSLMQMLLDTELKQISMGAIQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDWSTYLADYGQATSKYLRVNPSTALTLLEKVHRGMRDSSKKNNIFAQFRKNDRDKQKLIETVVKQLRSLVNGMSQHT", "length": 825, "header": "tr|A0A8V0Z432-1|A0A8V0Z432_CHICK Isoform 1 of Exocyst complex component OS=Gallus gallus OX=9031 GN=EXOC6 PE=3 SV=1 CANONICAL=A0A8V0Z432-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YX34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432/entry#A0A8V0YX34-1", "sequence": { "sequence": "MAESLPEHDRILQEIESTDTACVGPTLRSVYDDQPNAHQRFMEKLDACIRNHDREIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRLQDAGKEVIAQTEEIIRCRVQQRNITTVVEKLQLCLPVLEMYSKLKEQMKVKRAGYLKILKNNCRARANQL", "length": 165, "header": "tr|A0A8V0YX34-1|A0A8V0Z432_CHICK Computationally mapped isoform of Exocyst complex component OS=Gallus gallus OX=9031 GN=EXOC6 PE=3 SV=1 CANONICAL=A0A8V0Z432-1" }, "locus": { "chromosome": "6", "start_pos": 21454847, "end_pos": 21434639, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043173.1", "url": "https://www.ensembl.org/id/ENSGALT00010043173.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025643.1", "url": "https://www.ensembl.org/id/ENSGALP00010025643.1" } ] } }, { "isoform_ac": "A0A8V0YX44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432/entry#A0A8V0YX44-1", "sequence": { "sequence": "MEKLDACIRNHDREIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRLQDAGKEVIAQTEEIIRCRVQQRNITTVVEKLQLCLPVLEMYSKLKEQMKVKRYYSALKTMEQLENLYLPRVSQYRFCQIMIENLPKLREEIKEISMSDLKDFLESIRKHSDRIGETAMKQAQQQKTFSTTLQKHHNVNYGRNMHLGRSRILESRNEMTLKRTFEEDDEHDEEVLTAQDLVDFSPVYRCLHIYSVLGDGEIFENYYRKQRRKQARLVLQPQSSMHETVEGYRRYFSQIVGFFVVEDHILHVTQGLVTRTYTDELWNMALSKIIAVLRTHSSYCNDPDLVLELKNLIVVFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWSGLFRDIFEADNYSPIPVANEEEYKIVISKFPFQDSELDKQCFPKKLPMSQSVPQIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLQNLIKKPHIGLTELVQIIINTTHLELACKYLEDFISNITNISQVTVHTARLYGLSTFKDARHAAEGEIYTKLNQKIDEFIQIADYDWTMSESDGRASGYLMDLINFLRSTFQVFTHLPGKVAQTACMSACQHLSTSLMQMLLDTELKQISMGAIQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDWSTYLADYGQATSKYLRVNPTLCRDSSKKNNIFAQFRKNDRDKQKLIETVVKQLRSLVNGMSQHT", "length": 750, "header": "tr|A0A8V0YX44-1|A0A8V0Z432_CHICK Computationally mapped isoform of Exocyst complex component OS=Gallus gallus OX=9031 GN=EXOC6 PE=3 SV=1 CANONICAL=A0A8V0Z432-1" }, "locus": { "chromosome": "6", "start_pos": 21438173, "end_pos": 21371125, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043186.1", "url": "https://www.ensembl.org/id/ENSGALT00010043186.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025653.1", "url": "https://www.ensembl.org/id/ENSGALP00010025653.1" } ] } }, { "isoform_ac": "A0A8V0YX49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432/entry#A0A8V0YX49-1", "sequence": { "sequence": "MAESLPEHDRILQEIESTDTACVGPTLRSVYDDQPNAHQRFMEKLDACIRNHDREIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRLQDAGKEVIAQTEEIIRCRVQQRNITTVVEKLQLCLPVLEMYSKLKEQMKVKRYYSALKTMEQLENLYLPRVSQYRFCQIMIENLPKLREEIKEISMSDLKDFLESIRKHSDRIGETAMKQAQQQKTFSTTLQKHHNVNYGRNMHLGRSRILESRNEMTLKRTFEEDDEHDEEVLTAQDLVDFSPVYRCLHIYSVLGDGEIFENYYRKQRRKQARLVLQPQSSMHETVEGYRRYFSQIVGFFVVEDHILHVTQGLVTRTYTDELWNMALSKIIAVLRTHSSYCNDPDLVLELKNLIVVFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWSGLFRDIFEADNYSPIPVANEEEYKIVISKFPFQDSELDKQCFPKKLPMSQSVPQIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLQNLIKKPHIGLTELVQIIINTTHLELACKYLEDFISNITNISQVTVHTARLYGLSTFKDARHAAEGEIYTKLNQKIDEFIQIADYDWTMSESDGRASGYLMDLINFLRSTFQVFTHLPNNNNDHAAMSGKVAQTACMSACQHLSTSLMQMLLDTELKQISMGAIQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQETTYKAVKF", "length": 736, "header": "tr|A0A8V0YX49-1|A0A8V0Z432_CHICK Computationally mapped isoform of Exocyst complex component OS=Gallus gallus OX=9031 GN=EXOC6 PE=3 SV=1 CANONICAL=A0A8V0Z432-1" }, "locus": { "chromosome": "6", "start_pos": 21454847, "end_pos": 21385870, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043191.1", "url": "https://www.ensembl.org/id/ENSGALT00010043191.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025658.1", "url": "https://www.ensembl.org/id/ENSGALP00010025658.1" } ] } }, { "isoform_ac": "A0A8V0YX53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432/entry#A0A8V0YX53-1", "sequence": { "sequence": "MAESLPEHDRILQEIESTDTACVGPTLRSVYDDQPNAHQRFMEKLDACIRNHDREIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRLQDAGKEVIAQTEEIIRCRVQQRNITTVVEKLQLCLPVLEMYSKLKEQMKVKRYYSALKTMEQLENLYLPRVSQYRFCQIMIENLPKLREEIKEISMSDLKDFLESIRKHSDRIGETAMKQAQQQKTFSTTLQKHHNVNYGRNMHLGRSRILESRNEMTLKRTFEEDDEHDEEVLTAQDLVDFSPVYRCLHIYSVLGDGEIFENYYRKQRRKQARLVLQPQSSMHETVEGYRRYFSQIVGFFVVEDHILHVTQGLVTRTYTDELWNMALSKIIAVLRTHSSYCNDPDLVLELKNLIVVFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWSGLFRDIFEADNYSPIPVANEEEYKIVISKFPFQDSELDKQCFPKKLPMSQSVPQIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLQNLIKKPHIGLTELVQIIINTTHLELACKYLEDFISNITNISQVTVHTARLYGLSTFKDARHAAEGEIYTKLNQKIDEFIQIADYDWTMSESDGRASGYLMDLINFLRSTFQVFTHLPGKVAQTACMSACQHLSTSLMQMLLDTELKQISMGAIQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDWSTYLADYGQATSKYLRVNPSTALTLLEKMRDSSKKNNIFAQFRKNDRDKQKLIETVVKQLRSLVNGMSQHT", "length": 798, "header": "tr|A0A8V0YX53-1|A0A8V0Z432_CHICK Computationally mapped isoform of Exocyst complex component OS=Gallus gallus OX=9031 GN=EXOC6 PE=3 SV=1 CANONICAL=A0A8V0Z432-1" }, "locus": { "chromosome": "6", "start_pos": 21454847, "end_pos": 21371125, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043198.1", "url": "https://www.ensembl.org/id/ENSGALT00010043198.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025663.1", "url": "https://www.ensembl.org/id/ENSGALP00010025663.1" } ] } }, { "isoform_ac": "A0A8V0Z3Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432/entry#A0A8V0Z3Z8-1", "sequence": { "sequence": "MAESLPEHDRILQEIESTDTACVGPTLRSVYDDQPNAHQRFMEKLDACIRNHDREIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRLQDAGKEVIAQTEEIIRCRVQQRNITTVVEKLQLCLPVLEMYSKLKEQMKVKRYYSALKTMEQLENLYLPRVSQYRFCQIMIENLPKLREEIKEISMSDLKDFLESIRKHSDRIGETAMKQAQQQKTFSTTLQKHHNVNYGRNMHLGRSRILESRNEMTLKRTFEEDDEHDEEVLTAQDLVDFSPVYRCLHIYSVLGDGEIFENYYRKQRRKQARLVLQPQSSMHETVEGYRRYFSQIVGFFVVEDHILHVTQGLVTRTYTDELWNMALSKIIAVLRTHSSYCNDPDLVLELKNLIVVFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWSGLFRDIFEADNYSPIPVANEEEYKIVISKFPFQDSELDKQCFPKKLPMSQSVPQIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLQNLIKKPHIGLTELVQIIINTTHLELACKYLEDFISNITNISQVTVHTARLYGLSTFKDARHAAEGEIYTKLNQKIDEFIQIADYDWTMSESDGRASGYLMDLINFLRSTFQVFTHLPGKVAQTACMSACQHLSTSLMQMLLDTELKQISMGAIQQFNLDVIQCESPGPLHGVGLVHLPGRLRAGHLQVPAGQPQHGPHAPGESAQRNERLQQKEQHFCSVQEERSRQAEADRDRGEAAQEPGERHVPAHIGPLLQSWSLPRREVFHSHPFCPAVLSVGTVV", "length": 809, "header": "tr|A0A8V0Z3Z8-1|A0A8V0Z432_CHICK Computationally mapped isoform of Exocyst complex component OS=Gallus gallus OX=9031 GN=EXOC6 PE=3 SV=1 CANONICAL=A0A8V0Z432-1" }, "locus": { "chromosome": "6", "start_pos": 21454847, "end_pos": 21371030, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043179.1", "url": "https://www.ensembl.org/id/ENSGALT00010043179.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025647.1", "url": "https://www.ensembl.org/id/ENSGALP00010025647.1" } ] } }, { "isoform_ac": "A0A8V0Z432-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432/entry#A0A8V0Z432-1", "sequence": { "sequence": "MARKSRPNMSEMYLEENKDQIYENALAEIESFELPLGTTLRSVYDDQPNAHQRFMEKLDACIRNHDREIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRLQDAGKEVIAQTEEIIRCRVQQRNITTVVEKLQLCLPVLEMYSKLKEQMKVKRYYSALKTMEQLENLYLPRVSQYRFCQIMIENLPKLREEIKEISMSDLKDFLESIRKHSDRIGETAMKQAQQQKTFSTTLQKHHNVNYGRNMHLGRSRILESRNEMTLKRTFEEDDEHDEEVLTAQDLVDFSPVYRCLHIYSVLGDGEIFENYYRKQRRKQARLVLQPQSSMHETVEGYRRYFSQIVGFFVVEDHILHVTQGLVTRTYTDELWNMALSKIIAVLRTHSSYCNDPDLVLELKNLIVVFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWSGLFRDIFEADNYSPIPVANEEEYKIVISKFPFQDSELDKQCFPKKLPMSQSVPQIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLQNLIKKPHIGLTELVQIIINTTHLELACKYLEDFISNITNISQVTVHTARLYGLSTFKDARHAAEGEIYTKLNQKIDEFIQIADYDWTMSESDGRASGYLMDLINFLRSTFQVFTHLPNNNNDHAAMSGKVAQTACMSACQHLSTSLMQMLLDTELKQISMGAIQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDWSTYLADYGQATSKYLRVNPSTALTLLEKVHRGMRDSSKKNNIFAQFRKNDRDKQKLIETVVKQLRSLVNGMSQHT", "length": 825, "header": "tr|A0A8V0Z432-1|A0A8V0Z432_CHICK Isoform 1 of Exocyst complex component OS=Gallus gallus OX=9031 GN=EXOC6 PE=3 SV=1 CANONICAL=A0A8V0Z432-1" }, "locus": { "chromosome": "6", "start_pos": 21456784, "end_pos": 21371125, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043226.1", "url": "https://www.ensembl.org/id/ENSGALT00010043226.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025682.1", "url": "https://www.ensembl.org/id/ENSGALP00010025682.1" } ] } }, { "isoform_ac": "A0A8V0Z436-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432/entry#A0A8V0Z436-1", "sequence": { "sequence": "MARKSRPNMSEMYLEENKDQIYENALAEIESFELPLGTTLRSVYDDQPNAHQRFMEKLDACIRNHDREIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRLQDAGKEVIAQTEEIIRCRVQQRNITTVVEKLQLCLPVLEMYSKLKEQMKVKRYYSALKTMEQLENLYLPRVSQYRFCQIMIENLPKLREEIKEISMSDLKDFLESIRKHSDRIGETAMKQAQQQKTFSTTLQKHHNVNYGRNMHLGRSRILESRNEMTLKRTFEEDDEHDEEVLTAQDLVDFSPVYRCLHIYSVLGDGEIFENYYRKQRRKQARLVLQPQSSMHETVEGYRRYFSQIVGFFVVEDHILHVTQGLVTRTYTDELWNMALSKIIAVLRTHSSYCNDPDLVLELKNLIVVFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWSGLFRDIFEADNYSPIPVANEEEYKIVISKFPFQDSELDKQCFPKKLPMSQSVPQIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLQNLIKKPHIGLTELVQIIINTTHLELACKYLEDFISNITNISQVTVHTARLYGLSTFKDARHAAEGEIYTKLNQKIDEFIQIADYDWTMSESDGRASGYLMDLINFLRSTFQVFTHLPNNNNDHAAMSGKVAQTACMSACQHLSTSLMQMLLDTELKQISMGAIQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDWSTYLADYGQATSKYLRVNPSTALTLLEKMRDSSKKNNIFAQFRKNDRDKQKLIETVVKQLRSLVNGMSQHT", "length": 821, "header": "tr|A0A8V0Z436-1|A0A8V0Z432_CHICK Computationally mapped isoform of Exocyst complex component OS=Gallus gallus OX=9031 GN=EXOC6 PE=3 SV=1 CANONICAL=A0A8V0Z432-1" }, "locus": { "chromosome": "6", "start_pos": 21456784, "end_pos": 21371125, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043234.1", "url": "https://www.ensembl.org/id/ENSGALT00010043234.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025687.1", "url": "https://www.ensembl.org/id/ENSGALP00010025687.1" } ] } }, { "isoform_ac": "A0A8V0Z555-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432/entry#A0A8V0Z555-1", "sequence": { "sequence": "MAESLPEHDRILQEIESTDTACVGPTLRSVYDDQPNAHQRFMEKLDACIRNHDREIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRLQDAGKEVIAQTEEIIRCRVQQRNITTVVEKLQLCLPVLEMYSKLKEQMKVKRYYSALKTMEQLENLYLPRVSQYRFCQIMIENLPKLREEIKEISMSDLKDFLESIRKHSDRIGETAMKQAQQQKTFSTTLQKHHNVNYGRNMHLGRSRILESRNEMTLKRTFEEDDEHDEEVLTAQDLVDFSPVYRCLHIYSVLGDGEIFENYYRKQRRKQARLVLQPQSSMHETVEGYRRYFSQIVGFFVVEDHILHVTQGLVTRTYTDELWNMALSKIIAVLRTHSSYCNDPDLVLELKNLIVVFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWSGLFRDIFEADNYSPIPVANEEEYKIVISKFPFQDSELDKQCFPKKLPMSQSVPQIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLQNLIKKPHIGLTELVQIIINTTHLELACKYLEDFISNITNISQVTVHTARLYGLSTFKDARHAAEGEIYTKLNQKIDEFIQIADYDWTMSESDGRASGYLMDLINFLRSTFQVFTHLPGKVAQTACMSACQHLSTSLMQMLLDTELKQISMGAIQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQGLRVQADGTDRSNLARAVPSGA", "length": 739, "header": "tr|A0A8V0Z555-1|A0A8V0Z555_CHICK Computationally mapped isoform of Exocyst complex component OS=Gallus gallus OX=9031 GN=EXOC6 PE=3 SV=1 CANONICAL=A0A8V0Z432-1" }, "locus": { "chromosome": "6", "start_pos": 21454847, "end_pos": 21380530, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043203.1", "url": "https://www.ensembl.org/id/ENSGALT00010043203.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025666.1", "url": "https://www.ensembl.org/id/ENSGALP00010025666.1" } ] } }, { "isoform_ac": "A0A8V0ZB06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432/entry#A0A8V0ZB06-1", "sequence": { "sequence": "MAESLPEHDRILQEIESTDTACVGPTLRSVYDDQPNAHQRFMEKLDACIRNHDREIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRLQDAGKEVIAQTEEIIRCRVQQRNITTVVEKLQLCLPVLEMYSKLKEQMKVKRYYSALKTMEQLENLYLPRVSQYRFCQIMIENLPKLREEIKEISMSDLKDFLESIRKHSDRIGETAMKQAQQQKTFSTTLQKHHNVNYGRNMHLGRSRILESRNEMTLKRTFEEDDEHDEEVLTAQDLVDFSPVYRCLHIYSVLGDGEIFENYYRKQRRKQARLVLQPQSSMHETVEGYRRYFSQIVGFFVVEDHILHVTQGLVTRTYTDELWNMALSKIIAVLRTHSSYCNDPDLVLELKNLIVVFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWSGLFRDIFEADNYSPIPVANEEEYKIVISKFPFQDSELDKQCFPKKLPMSQSVPQIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLQNLIKKPHIGLTELVQIIINTTHLELACKYLEDFISNITNISQVTVHTARLYGLSTFKDARHAAEGEIYTKLNQKIDEFIQIADYDWTMSESDGRASGYLMDLINFLRSTFQVFTHLPLLDLFMVWDWSTYLADYGQATSKYLRVNPSTALTLLEKVHRGMRDSSKKNNIFAQFRKNDRDKQKLIETVVKQLRSLVNGMSQHT", "length": 730, "header": "tr|A0A8V0ZB06-1|A0A8V0Z432_CHICK Computationally mapped isoform of Exocyst complex component OS=Gallus gallus OX=9031 GN=EXOC6 PE=3 SV=1 CANONICAL=A0A8V0Z432-1" }, "locus": { "chromosome": "6", "start_pos": 21454847, "end_pos": 21371125, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043209.1", "url": "https://www.ensembl.org/id/ENSGALT00010043209.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025669.1", "url": "https://www.ensembl.org/id/ENSGALP00010025669.1" } ] } }, { "isoform_ac": "A0A8V0ZB11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432/entry#A0A8V0ZB11-1", "sequence": { "sequence": "MARKSRPNMSEMYLEENKDQIYENALAEIESFELPLGTTLRSVYDDQPNAHQRFMEKLDACIRNHDREIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRLQDAGKEVIAQTEEIIRCRVQQRNITTVVEKLQLCLPVLEMYSKLKEQMKVKRYYSALKTMEQLENLYLPRVSQYRFCQIMIENLPKLREEIKEISMSDLKDFLESIRKHSDRIGETAMKQAQQQKTFSTTLQKHHNVNYGRNMHLGRSRILESRNEMTLKRTFEEDDEHDEEVLTAQDLVDFSPVYRCLHIYSVLGDGEIFENYYRKQRRKQARLVLQPQSSMHETVEGYRRYFSQIVGFFVVEDHILHVTQGLVTRTYTDELWNMALSKIIAVLRTHSSYCNDPDLVLELKNLIVVFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWSGLFRDIFEADNYSPIPVANEEEYKIVISKFPFQDSELDKQCFPKKLPMSQSVPQIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLQNLIKKPHIGLTELVQIIINTTHLELACKYLEDFISNITNISQVTVHTARLYGLSTFKDARHAAEGEIYTKLNQKIDEFIQIADYDWTMSESDGRASGYLMDLINFLRSTFQVFTHLPGKVAQTACMSACQHLSTSLMQMLLDTELKQISMGAIQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDWSTYLADYGQATSKYLRVNPSTALTLLEKVHRGMRDSSKKNNIFAQFRKNDRDKQKLIETVVKQLRSLVNGMSQHT", "length": 815, "header": "tr|A0A8V0ZB11-1|A0A8V0Z432_CHICK Computationally mapped isoform of Exocyst complex component OS=Gallus gallus OX=9031 GN=EXOC6 PE=3 SV=1 CANONICAL=A0A8V0Z432-1" }, "locus": { "chromosome": "6", "start_pos": 21456784, "end_pos": 21371125, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043215.1", "url": "https://www.ensembl.org/id/ENSGALT00010043215.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025674.1", "url": "https://www.ensembl.org/id/ENSGALP00010025674.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-264876", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-264876", "resource": "Reactome", "description": "Insulin processing" }, { "id": "R-GGA-5620916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620916", "resource": "Reactome", "description": "VxPx cargo-targeting to cilium" } ], "orthologs": [ { "uniprot_canonical_ac": "F4JHH5-1", "protein_name": "Exocyst complex component SEC15B", "gene_name": "SEC15B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MQSSKGRRKVGSTTAGAGIDSAEKLDELLISSAICNGEDLGPFVRKTFGTGKPETLLHHLKFFARSKESEIEEVCKAHYQDFIHAVDDLKSLLSDVESLKSALSDSNSKLQSVAAPLLSSLDSLVEAQTVSKNVDLAIGAVTHCVRVMELVSRANQHLQSGNFYMALKCVDSIESDFMEKTPSSTLKRMLENRIPAIRSYVERKVNKEFGDWLVEIRVVSRNLGQLAIGEASAARQREEELRIKQRQAEEQSRLSLRDCVYALNEEEDDEFGSGHEGSDGGSSGGGLLGFDLTPLYRAYHIHQTLSLGDTFKQYYYNNRDLQLTSDFQIAGFFIVEDRVLRTGGGLISKLEVETLWDTAVTKMCAVLEDQFSRMQTANHLLLIKDYVSLLGVSLRRYGYAVDSLLEVLSKHRDKYHELLLSDCRKQITEALSADKFEQMLMKKEYEYSMNVLSFQLQTSEIVPAFPFIAPFSTTVPDCCRIVRSFIEDSVSFMSHGGQLDFYDVVKKYLDRLLGEVLDEALLKLISTSVHGVSQAMQVAANMAVFERACDFFFRHAAHLSGVPLRMAERGRRHFPLTKSQNTAEDTLSGMLKKKIDGFMTLLENVNWTSDDIPQGGNEYMNEVLIYLETLVSTAQQILPAKVLKRVLRDVLAHISEKIVGTLCGDLVKRLSMAAIKGLDVDIQLLDSFTENLTPLLTDKEAREMKKAFVEIRQMINLLLSSHPENFVNPVIRERSYNALDYRKVATVSEKFRDPSDSIFGTFGTRGSRQNPKNKSLDALIKRLKDVS", "length": 787 }, "evidence": [ { "id": "A0A8V0Z432", "url": "https://omabrowser.org/oma/group/A0A8V0Z432/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O54923-1", "protein_name": "Exocyst complex component 6", "gene_name": "Exoc6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAESGEALGTVPEHERILQEIESTDTACVGPTLRSVYDGQPNAHKKFMEKLDACIRNHDKEIEKMCNFHHQGFVDAITELLKVRADAEKLKVQVTDTNRRFQDAGKEVIEQTEDIIRCRIQQRNITTVVEKLQLCLPVLEMYSKLKEQMSMQRYYSALKTMEQLENVYFPRVSQYRFCQLMMDTLPKLREDIKDISMSDLKDFLESIRKHSDKIGETAMKQAQQQKSFSIAVQKQTNMRFGKNMHVNNDRTLEEKSDIILKHTLEEEAENDEEVLTVQDLVDFSPVYRCSHIYSALGDEETFENYYRKQRKKQARLVLQPQSSVHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELWNMALSKIIAVLRAHSSYCTDPDLVLELKNLIVIFADTLQGYGFSVNRLFDLLFEIRDQYNETLLKKWAGIFRDIFEEDNYSPIPIGSEEEYKMVISKFPFQDPDLEKQSFPKKFPMSQSVPLIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRILSSCLLNLIRKPHIGLTELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEIYTKLNQKIDEFVQLADYDWTMAESDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMSACQHLSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDWSTYLADYGQPASKYLRVNPHAALTLLEKMKDTSKKNNIFAQFRKNDRDRQKLIETVVKQLRGLVTGMSQHM", "length": 804 }, "evidence": [ { "id": "A0A8V0Z432", "url": "https://omabrowser.org/oma/group/A0A8V0Z432/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54B27-1", "protein_name": "Exocyst complex component 6", "gene_name": "exoc6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKKQKEEINTAGGSVILKTMVRDKDKEQKEEKREKKEKKRLEKKEAENVKKEKKKEKKELKKIGKAGRSGSITSDSSTHSGAQEFDSYGNDSNGGGGGLSASIDSNGLSSSGQPMQTRHLEKEVGEKQGIYSLSSQDRSSSLPHSSQDDQAKPLITESEIFSSESFLIAVSDTDHLGPAIKSVFENNKEKEVIKILNAYIAQKDLDIEKICGENHEGFINSVTAFLGLKGENLDLKQDVINLNYELQEIGRKYVTKAEELFAYKQIKDNIKRTKEVLNNCQYAILLGMKVDEYVQQKKYYQAIKNMDQLHNVYLKKLSDFQFARNMDYNIPVLKEKIKKLVKDEFNQWMVEIKEKSAVIGKLGMIQTSKKLLKEREINPLKIKTTFGENEQIWDKILDIPPIINSSSIGSLALYPTLNSPVTAPIYSPNSGKTPSSFGFNKQINEKDLKEDINQFSPFDESDIQFHPLYQCLFIHASIGQLEEFQAYYTLNRLLQFQLVIQPKESGQVWELFLQQILGYFMVESKVIDSTEPFLSKTTINDSWNSALVKVTSVLQELFTHCVDTQPLIAFKKFVLIFTNTMSFYSYHVQPLYYFLDTMKEKYCQFSIKEAVERFTIILERDSHCSLIIESLEEYKSLILANKLDILERQQLRQLQNSLNNNQFQFGDKNLNNNNNNDDDDDYFDEDENEDDKISKRLPKSFLFSKMVPQFYTLIKKFISEFYEFSDQLTENENFIIRSTDTLIKKINEVLYSYLTQSQAVPQVIQLVINLQHLISGCSFFKDYLNSLILGEDYQKNQSIVNETNKVILNSQNLLYTTKSHGEKLIIKLCEQKIEDLMSSAANIEWFPQNAIDDRPRDYIIDVCTFLEVTLPFISPLSQNLKEEFITKAFKNISESLFSLIYDDQLKKLNLQGVKSFDADLKYIETYVKEKANEKERTTTTSRNMVGYFVELRQLTNFLLSDNPEDFVDPKIKAKHYNLITNIPQLLNILNKYKEESKGFTTSKEIKDRNKKIADAIKKIKDSL", "length": 1025 }, "evidence": [ { "id": "A0A8V0Z432", "url": "https://omabrowser.org/oma/group/A0A8V0Z432/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8TAG9-1", "protein_name": "Exocyst complex component 6", "gene_name": "EXOC6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAENSESLGTVPEHERILQEIESTDTACVGPTLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKMCNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNITTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRDRIPEERNETVLKHSLEEEDENEEEILTVQDLVDFSPVYRCLHIYSVLGDEETFENYYRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELWNMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQSFPKKFPMSQSVPHIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPHIGLTELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEIYTKLNQKIDEFVQLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMSACQHLSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDWSTYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRDKQKLIETVVKQLRSLVNGMSQHM", "length": 804 }, "evidence": [ { "id": "A0A8V0Z432", "url": "https://omabrowser.org/oma/group/A0A8V0Z432/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VDE6-1", "protein_name": "Exocyst complex component 6", "gene_name": "Sec15", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKVTVQDIEAVDDYWGPTFRSILEGNNTKQIGDQLEQRIRSHDKEIERICNLYYQGFIDSIQELLQVRTQAQQLHNEVHSLDTSLRQISASLIQQGNDLVRARQIESNLASAIEALKSCLPALECYMKFTQQAKNKQYYQALRTLETLETEHLTRLKTHNYRFATQMQIQIPIIKENIRRSSASDFREFLENIRKFSPRIGELAITHTKQLQKRDINAIIAEHMQQMNGGEAGGAGAGGDDDGANVSAQDLIDFSPIYRCLHIYMVLGQREYFEKDYRQQRRDQAKLVLQPPPNMHDNLEAYKTYICAIVGFFVVEDHVKNTAGDVVTSSYLEDLWSSSLTKFVNEISMSSSSCTDPNILLRIKNLIMLSINTFKCYGYTVNILWELLHNMRDHYNEVLLQRWVHVFREILDKEQFLPMVVQNTEEYECIIERFPFHSEQLENAPFPKKFPFSRMVPEVYHQAKEFMYACMKFAEELTLSPNEVAAMVRKAANLLLTRSFSGCLSVVFRQPSITLTQLIQIIIDTQYLEKAGPFLDEFVCHMTNTERSVSQTPSAMFHVARQDAEKQVGLRICSKIDEFFELSAYDWLLVEPPGIASAFITDMISYLKSTFDSFAFKLPHIAQAACRRTFEHIAEKIYSIMYDEDVKQISTGALTQINLDLMQCEFFAASEPVPGLKEGELSKYFLRNRQLLDLLILEEWSTYFHDYGKQENRYHLVQPQSIIVILEKIREADKKPIFSLVRKNDKKKLLETVLKQLKHIADRQN", "length": 766 }, "evidence": [ { "id": "A0A8V0Z432", "url": "https://omabrowser.org/oma/group/A0A8V0Z432/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z432", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432" } ], "pmid": "" }, { "name": "vesicle tethering involved in exocytosis", "id": "GO:0090522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090522", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z432", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z432", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432" } ], "pmid": "" }, { "name": "Golgi to plasma membrane transport", "id": "GO:0006893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z432", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z432", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z432", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { 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"Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z432", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z432" }, { "id": "PF04091", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04091" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exocyst complex subunit EXOC6/Sec15 C-terminal", "eco_id": "ECO_0000259", "start_pos": 420, "end_pos": 778, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 432, "end_pos": 434 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 560, "end_pos": 562 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 580, "end_pos": 582 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3Q4-1", "uniprot_ac": "A0A8V0Z3Q4", "uniprot_id": "A0A8V0Z3Q4_CHICK", "mass": { "chemical_mass": 32689.0, "monoisotopic_mass": 32689.0 }, "refseq": { "ac": "XP_025005929", "name": "lysophosphatidic acid receptor 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005929" }, "gene_names": [ { "name": "LOC422150", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4" } ] }, { "name": "LOC422150", "type": "synonym", "evidence": [ { "id": "XP_025005929", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005929" } ] } ], "protein_names": [ { "name": "G-protein coupled receptors family 1 profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4/entry#names_and_taxonomy" } ] }, { "name": "lysophosphatidic acid receptor 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025005929", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005929" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025005929.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025005929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005929" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC422150", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z3Q4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3Q4", "database": "AlphaFoldDB", "categories": [] }, { "id": "422150", "url": "https://www.ncbi.nlm.nih.gov/gene/422150", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422150", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422150", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISMERDH", "url": "https://omabrowser.org/oma/group/ISMERDH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXB6", "url": "https://www.orthodb.org/?gene=A0A8V0YXB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3P9", "url": "https://www.orthodb.org/?gene=A0A8V0Z3P9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3Q4", "url": "https://www.orthodb.org/?gene=A0A8V0Z3Q4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232:SF83", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232:SF83", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025005929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005929", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YXB6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3P9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3P9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYRAGPALKQGCSKKQTGNGKALETICSGIPGSQPEPMGALCECGSAAARRYERGRDTFLSSALPARCYREGYSSLAGISRERDHMKDFRRYLVLKYIQYLVLSSSNTISTLLGVLGSGYVMLILQSSRVSSKSTAVFISSLAKADLLIFVSAVAELFLWSSSVVVPRTAFTSALLQNLLTANTHISALLLSCVAVEAYLITFLPTESRSLRTVRNAGLTSRAIWLLVAAECTLLQADDVLKASSTSPSCSPGVWLLHLSSGAAALLRALSYLLGILLRIVNVYIYYKIFFSVSNRSSVRTN", "length": 302, "header": "tr|A0A8V0Z3Q4-1|A0A8V0Z3Q4_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC422150 PE=4 SV=1 CANONICAL=A0A8V0Z3Q4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4/entry#A0A8V0YXB6-1", "sequence": { "sequence": "MKDFRRYLVLKYIQYLVLSSSNTISTLLGVLGSGYVMLILQSSRVSSKSTAVFISSLAKADLLIFVSAVAELFLWSSSVVVPRTAFTSALLQNLLTANTHISALLLSCVAVEAYLITFLPTESRSLRTVRNAGLTSRAIWLLVAAECTLLQADDVLKASSTSPSCSPGVWLLHLSSGAAALLRALSYLLGILLRIVNVYIYYKIFFSVSNRSSVRTN", "length": 217, "header": "tr|A0A8V0YXB6-1|A0A8V0Z3Q4_CHICK Computationally mapped isoform of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC422150 PE=4 SV=1 CANONICAL=A0A8V0Z3Q4-1" }, "locus": { "chromosome": "4", "start_pos": 1325146, "end_pos": 1324496, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043285.1", "url": "https://www.ensembl.org/id/ENSGALT00010043285.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025723.1", "url": "https://www.ensembl.org/id/ENSGALP00010025723.1" } ] } }, { "isoform_ac": "A0A8V0Z3P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4/entry#A0A8V0Z3P9-1", "sequence": { "sequence": "MHSRYSSLAGISRERDHMKDFRRYLVLKYIQYLVLSSSNTISTLLGVLGSGYVMLILQSSRVSSKSTAVFISSLAKADLLIFVSAVAELFLWSSSVVVPRTAFTSALLQNLLTANTHISALLLSCVAVEAYLITFLPTESRSLRTVRNAGLTSRAIWLLVAAECTLLQADDVLKASSTSPSCSPGVWLLHLSSGAAALLRALSYLLGILLRIVNVYIYYKIFFSVSNRSSVRTN", "length": 234, "header": "tr|A0A8V0Z3P9-1|A0A8V0Z3P9_CHICK Computationally mapped isoform of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC422150 PE=4 SV=1 CANONICAL=A0A8V0Z3Q4-1" }, "locus": { "chromosome": "4", "start_pos": 1325146, "end_pos": 1324445, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043287.1", "url": "https://www.ensembl.org/id/ENSGALT00010043287.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025725.1", "url": "https://www.ensembl.org/id/ENSGALP00010025725.1" } ] } }, { "isoform_ac": "A0A8V0Z3Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4/entry#A0A8V0Z3Q4-1", "sequence": { "sequence": "MYRAGPALKQGCSKKQTGNGKALETICSGIPGSQPEPMGALCECGSAAARRYERGRDTFLSSALPARCYREGYSSLAGISRERDHMKDFRRYLVLKYIQYLVLSSSNTISTLLGVLGSGYVMLILQSSRVSSKSTAVFISSLAKADLLIFVSAVAELFLWSSSVVVPRTAFTSALLQNLLTANTHISALLLSCVAVEAYLITFLPTESRSLRTVRNAGLTSRAIWLLVAAECTLLQADDVLKASSTSPSCSPGVWLLHLSSGAAALLRALSYLLGILLRIVNVYIYYKIFFSVSNRSSVRTN", "length": 302, "header": "tr|A0A8V0Z3Q4-1|A0A8V0Z3Q4_CHICK Isoform 1 of G-protein coupled receptors family 1 profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC422150 PE=4 SV=1 CANONICAL=A0A8V0Z3Q4-1" }, "locus": { "chromosome": "4", "start_pos": 1325146, "end_pos": 1319515, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043294.1", "url": "https://www.ensembl.org/id/ENSGALT00010043294.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025730.1", "url": "https://www.ensembl.org/id/ENSGALP00010025730.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422150", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422150", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZRV6-1", "protein_name": "RCG38062-like", "gene_name": "LOC100359656", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDLRRYLVFKYIQYLVLPSPNIIMTLLGSLASVYVMLVLTFPSVSRKPTAVLIGSIAQADILVGCSMLSAVSEGIIESESSSASFQSALRQNFQIANIHASSLLLSCVTLEAFLITFLPVETRHVRNVRCATVTSKLIWAVVSIECFLYQLECVKGLNISYLGIQRQVQLLMSFFYEAIRLMKLLTYPIGVLLRIFNVYLFYKMYFRDKYS", "length": 212 }, "evidence": [ { "id": "A0A8V0Z3Q4", "url": "https://omabrowser.org/oma/group/A0A8V0Z3Q4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Q4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 302, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 295, "end_pos": 297 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z488-1", "uniprot_ac": "A0A8V0Z488", "uniprot_id": "A0A8V0Z488_CHICK", "mass": { "chemical_mass": 31476.0, "monoisotopic_mass": 31476.0 }, "refseq": {}, "gene_names": [ { "name": "EIF4E2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488" } ] } ], "protein_names": [ { "name": "Eukaryotic translation initiation factor 4E type 2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488/entry#names_and_taxonomy" } ] }, { "name": "Eukaryotic translation initiation factor 4E-like 3", "type": "synonym", "evidence": [ { "id": "A0A8V0Z488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488/entry#names_and_taxonomy" } ] }, { "name": "eIF4E-like protein 4E-LP", "type": "synonym", "evidence": [ { "id": "A0A8V0Z488", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation. In association with GIGYF2, assists ribosome-associated quality control (RQC) by sequestering the mRNA cap, blocking ribosome initiation and decreasing the translational load on problematic messages. Part of a pathway that works in parallel to RQC-mediated degradation of the stalled nascent polypeptide. GIGYF2 and EIF4E2 work downstream and independently of ZNF598, which seems to work as a scaffold that can recruit them to faulty mRNA even if alternative recruitment mechanisms may exist.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5C0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C0#function" }, { "database": "UniProtKB", "id": "ARBA00054780", "url": "https://www.uniprot.org/uniprotkb/ARBA00054780#function" }, { "database": "UniProtKB", "id": "A0A8V0YXC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXC2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZB67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB67#function" }, { "database": "UniProtKB", "id": "A0A8V0ZB72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB72#function" }, { "database": "UniProtKB", "id": "A0A8V0Z488", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488#function" } ] }, { "annotation": "Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation. Acts as a repressor of translation initiation. In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap. In P-bodies, component of a complex that promotes miRNA-mediated translational repression. Involved in virus-induced host response by mediating miRNA MIR34A-induced translational silencing which controls IFNB1 production by a negative feedback mechanism.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z5C0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C0#function" }, { "database": "UniProtKB", "id": "ARBA00054290", "url": "https://www.uniprot.org/uniprotkb/ARBA00054290#function" }, { "database": "UniProtKB", "id": "A0A8V0YXC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXC2#function" }, { "database": "UniProtKB", "id": "A0A8V0ZB67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB67#function" }, { "database": "UniProtKB", "id": "A0A8V0ZB72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB72#function" }, { "database": "UniProtKB", "id": "A0A8V0Z488", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z488", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EIF4E2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488", "locus": { "chromosome": "9", "start_pos": 15310583, "end_pos": 15329151, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017905", "url": "https://www.ensembl.org/id/ENSGALG00010017905" } ] } } ], "crossref": [ { "id": "A0A8V0Z488", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z488", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXC2", "url": "https://www.orthodb.org/?gene=A0A8V0YXC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z488", "url": "https://www.orthodb.org/?gene=A0A8V0Z488", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5C0", "url": "https://www.orthodb.org/?gene=A0A8V0Z5C0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB58", "url": "https://www.orthodb.org/?gene=A0A8V0ZB58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB67", "url": "https://www.orthodb.org/?gene=A0A8V0ZB67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB72", "url": "https://www.orthodb.org/?gene=A0A8V0ZB72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11960", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11960", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11960:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11960:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YXC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z488", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z488-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5C0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5C0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB58", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB67", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB72", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNKFDALKDDDSGDHDQNEENNTQKDSEKEKNDREKPQSTTKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSINHDQEDFCAPGDAQKVNSDAVERGICHPALQEGSVTQTPRAWEEFHGLVNSSGR", "length": 275, "header": "tr|A0A8V0Z488-1|A0A8V0Z488_CHICK Isoform 1 of Eukaryotic translation initiation factor 4E type 2 OS=Gallus gallus OX=9031 GN=EIF4E2 PE=1 SV=1 CANONICAL=A0A8V0Z488-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488/entry#A0A8V0YXC2-1", "sequence": { "sequence": "MNNKFDALKDDDSGDHDQNEENNTQKDSEKEKNDREKPQSTTKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSINSSEVSVTL", "length": 230, "header": "tr|A0A8V0YXC2-1|A0A8V0Z488_CHICK Computationally mapped isoform of Eukaryotic translation initiation factor 4E type 2 OS=Gallus gallus OX=9031 GN=EIF4E2 PE=1 SV=1 CANONICAL=A0A8V0Z488-1" }, "locus": { "chromosome": "9", "start_pos": 15329007, "end_pos": 15317048, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043291.1", "url": "https://www.ensembl.org/id/ENSGALT00010043291.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025728.1", "url": "https://www.ensembl.org/id/ENSGALP00010025728.1" } ] } }, { "isoform_ac": "A0A8V0Z488-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488/entry#A0A8V0Z488-1", "sequence": { "sequence": "MNNKFDALKDDDSGDHDQNEENNTQKDSEKEKNDREKPQSTTKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSINHDQEDFCAPGDAQKVNSDAVERGICHPALQEGSVTQTPRAWEEFHGLVNSSGR", "length": 275, "header": "tr|A0A8V0Z488-1|A0A8V0Z488_CHICK Isoform 1 of Eukaryotic translation initiation factor 4E type 2 OS=Gallus gallus OX=9031 GN=EIF4E2 PE=1 SV=1 CANONICAL=A0A8V0Z488-1" }, "locus": { "chromosome": "9", "start_pos": 15329007, "end_pos": 15313623, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043305.1", "url": "https://www.ensembl.org/id/ENSGALT00010043305.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025737.1", "url": "https://www.ensembl.org/id/ENSGALP00010025737.1" } ] } }, { "isoform_ac": "A0A8V0Z5C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z488/entry#A0A8V0Z5C0-1", "sequence": { "sequence": "MAAAPGPGCGEPGKGLKDDDSGDHDQNEENNTQKDSEKEKNDREKPQSTTKRKAVVPGPAEHPLQYNYTFWYSRRTPGRPTSSQSYEQNIKQIGTFASVEQFWRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVRFQDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEYKTHTDSIKAWEEFHGLVNSSGR", "length": 243, "header": "tr|A0A8V0Z5C0-1|A0A8V0Z488_CHICK Computationally mapped 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"https://www.uniprot.org/uniprotkb/A0A8V0YXI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXY3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXY3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4M3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4N4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNEQVILWTITAGSKFTSERSRFVADGSGRTAQPGAVHLAEWNISCLSRTWSMAMSDVSESVVLSNGSILSNATSPGIVATNDGDVAFQQLPSKETPRAKANPNGCLQFNGTIKPSFLPLDNQRTQQMLSQCCHPCPYHHSLSNHNNRQECHSVVSSSAPSPMTSCCMQPHTEYSASICRKHTPIYQPACCLQPSPSFCLHHQWPDHFQHQPVQQHIARIRPARPFKLPKSYAALIADWPVVVLGMCTVLIVVCALVGILVPDLPDFSDPLLGFEPRGTAIGQRLVTWNNMVKNTGYKATLANYPFKYADEQAKSHQDDRWSDDHYEREKRQAEWNFHKDTFFCDIPSDRYSRVVFTSTEGENLWNLNAIKSMCNVDNLRIRSHSQFGDLCQRATAASCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKYYYNGTLGPDCWDMNAKRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFLSPKTADYVLPALKYSMLFSPTEKGESMMSIYLDNFENWNSSDGVTTVTGIEFGIKHSLFQDYLLMDTVYPAIAIVIVLLVMCVYTKSMFITLMTMFAIISSLIVSYFLYRVVFNFEFFPFMNLTALIILVGIGADDAFVLCDVWNYTKFDKPHAGTSETVSITLQHAALSMFVTSFTTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVVVLHERYLLNIFSCFKKPQQRVYNNKNCWTVLCQMFHKVIFAVSEASRIFFEKVLPCIVIKFRYIWLFWFLALTVGGAYIVCVNPKMKLPSLELSEFQVFRSSHPFERYDAEYKKLFMFERVHHGEELHMPITVIWGVMPEDNGDPLNPKSKGKLQLDSSFNIASPASQVWILRFCQKLRNQTFFYQTEEQDFTSCFIETFKQWMENQDCDEPSLYPCCSHWSFPYKQEVFELCIKRAIMELERSTGYHLDSKTPGPRFDLNDTIRAVVLEFQSTYLFTLAYEKMHQFYKEVDSWISSELSSAPEGLSNGWFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLGPQGTCGQIPLPKKLRCNAFSQTFSGAQGGRGQNKSHPISKYQLDSRGQKPEMEHEHYELEPLASQAGICNPAEKVTYEETHICSELFSSRSQNTCMPMHSVYNSEVSKSIKNVASSAVLQSSIDQRALCPLFSQNRQCSCPDPYKQVTVKWSPHSCQQLSDPFCYQCSPSPGAVQIQSSVTPINTLQQTTEGYVHPVQHVLHCSCLQGRLKRTMTQNSLPKNFFLQSVQQLQAHQRVNRTDSHAHQNPEENIRTVPKVMSSSQFLCRNAGPLIVHCSECENSVPNNQKGLCQKADKCDEKGGTEANGVESKKASMSKQKKKAESKIDQCSLQNDQVLKGDQAAKKHLLNRSAGEAHCEGCHENSHCCSTAVVVKCNSVDCQMPNIEANVPPMLMRPELSNESLLIKTL", "length": 1595, "header": "tr|A0A8V0Z4P7-1|A0A8V0Z4P7_CHICK Isoform 1 of Protein dispatched homolog 1 OS=Gallus gallus OX=9031 GN=DISP1 PE=3 SV=1 CANONICAL=A0A8V0Z4P7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7/entry#A0A8V0YXI4-1", "sequence": { "sequence": "MIRSHSQFGDLCQRATAASCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKYYYNGTLGPDCWDMNAKRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFLSPKTADYVLPALKYSMLFSPTEKGESMMSIYLDNFENWNSSDGVTTVTGIEFGIKHSLFQDYLLMDTVYPAIAIVIVLLVMCVYTKSMFITLMTMFAIISSLIVSYFLYRVVFNFEFFPFMNLTALIILVGIGADDAFVLCDVWNYTKFDKPHAGTSETVSITLQHAALSMFVTSFTTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVVVLHERYLLNIFSCFKKPQQRVYNNKNCWTVLCQMFHKVIFAVSEASRIFFEKVLPCIVIKFRYIWLFWFLALTVGGAYIVCVNPKMKLPSLELSEFQVFRSSHPFERYDAEYKKLFMFERVHHGEELHMPITVIWGVMPEDNGDPLNPKSKGKLQLDSSFNIASPASQVWILRFCQKLRNQTFFYQTEEQDFTSCFIETFKQWMENQDCDEPSLYPCCSHWSFPYKQEVFELCIKRAIMELERSTGYHLDSKTPGPRFDLNDTIRAVVLEFQSTYLFTLAYEKMHQFYKEVDSWISSELSSAPEGLSNGWFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLGPQGTCGQIPLPKKLRCNAFSQTFSGAQGGRGQNKSHPISKYQLDSRGQKPEMEHEHYELEPLASQAGICNPAEKVTYEETHICSELFSSRSQNTCMPMHSVYNSEVSKSIKNVASSAVLQSSIDQRALCPLFSQNRQCSCPDPYKQVTVKWSPHSCQQLSDPFCYQCSPSPGAVQIQSSVTPINTLQQTTEGYVHPVQHVLHCSCLQGRLKRTMTQNSLPKNFFLQSVQQLQAHQRVNRTDSHAHQNPEENIRTVPKVMSSSQFLCRNAGPLIVHCSECENSVPNNQKGLCQKADKCDEKGGTEANGVESKKASMSKQKKKAESKIDQCSLQNDQVLKGDQAAKKHLLNRSAGEAHCEGCHENSHCCSTAVVVKCNSVDCQMPNIEANVPPMLMRPELSNESLLIKTL", "length": 1215, "header": "tr|A0A8V0YXI4-1|A0A8V0Z4P7_CHICK Computationally mapped isoform of Protein dispatched homolog 1 OS=Gallus gallus OX=9031 GN=DISP1 PE=3 SV=1 CANONICAL=A0A8V0Z4P7-1" }, "locus": { "chromosome": "3", "start_pos": 17581147, "end_pos": 17577056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040483.1", "url": "https://www.ensembl.org/id/ENSGALT00010040483.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023495.1", "url": "https://www.ensembl.org/id/ENSGALP00010023495.1" } ] } }, { "isoform_ac": "A0A8V0YXY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7/entry#A0A8V0YXY3-1", "sequence": { "sequence": "MAMSDVSESVVLSNGSILSNATSPGIVATNDGDVAFQQLPSKETPRAKANPNGCLQFNGTIKPSFLPLDNQRTQQMLSQCCHPCPYHHSLSNHNNRQECHSVVSSSAPSPMTSCCMQPHTEYSASICRKHTPIYQPACCLQPSPSFCLHHQWPDHFQHQPVQQHIARIRPARPFKLPKSYAALIADWPVVVLGMCTVLIVVCALVGILVPDLPDFSDPLLGFEPRGTAIGQRLVTWNNMVKNTGYKATLANYPFKYADEQAKSHQDDRWSDDHYEREKRQAEWNFHKDTFFCDIPSDRYSRVVFTSTEGENLWNLNAIKSMCNVDNLRIRSHSQFGDLCQRATAASCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKYYYNGTLGPDCWDMNAKRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFLSPKTADYVLPALKYSMLFSPTEKGESMMSIYLDNFENWNSSDGVTTVTGIEFGIKHSLFQDYLLMDTVYPAIAIVIVLLVMCVYTKSMFITLMTMFAIISSLIVSYFLYRVVFNFEFFPFMNLTALIILVGIGADDAFVLCDVWNYTKFDKPHAGTSETVSITLQHAALSMFVTSFTTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVVVLHERYLLNIFSCFKKPQQRVYNNKNCWTVLCQMFHKVIFAVSEASRIFFEKVLPCIVIKFRYIWLFWFLALTVGGAYIVCVNPKMKLPSLELSEFQVFRSSHPFERYDAEYKKLFMFERVHHGEELHMPITVIWGVMPEDNGDPLNPKSKGKLQLDSSFNIASPASQVWILRFCQKLRNQTFFYQTEEQDFTSCFIETFKQWMENQDCDEPSLYPCCSHWSFPYKQEVFELCIKRAIMELERSTGYHLDSKTPGPRFDLNDTIRAVVLEFQSTYLFTLAYEKMHQFYKEVDSWISSELSSAPEGLSNGWFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLGPQGTCGQIPLPKKLRCNAFSQTFSGAQGGRGQNKSHPISKYQLDSRGQKPEMEHEHYELEPLASQAGICNPAEKVTYEETHICSELFSSRSQNTCMPMHSVYNSEVSKSIKNVASSAVLQSSIDQRALCPLFSQNRQCSCPDPYKQVTVKWSPHSCQQLSDPFCYQCSPSPGAVQIQSSVTPINTLQQTTEGYVHPVQHVLHCSCLQGRLKRTMTQNSLPKNFFLQSVQQLQAHQRVNRTDSHAHQNPEENIRTVPKVMSSSQFLCRNAGPLIVHCSECENSVPNNQKGLCQKADKCDEKGGTEANGVESKKASMSKQKKKAESKIDQCSLQNDQVLKGDQAAKKHLLNRSAGEAHCEGCHENSHCCSTAVVVKCNSVDCQMPNIEANVPPMLMRPELSNESLLIKTL", "length": 1542, "header": "tr|A0A8V0YXY3-1|A0A8V0Z4P7_CHICK Computationally mapped isoform of Protein dispatched homolog 1 OS=Gallus gallus OX=9031 GN=DISP1 PE=3 SV=1 CANONICAL=A0A8V0Z4P7-1" }, "locus": { "chromosome": "3", "start_pos": 17609186, "end_pos": 17577056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040493.1", "url": "https://www.ensembl.org/id/ENSGALT00010040493.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023502.1", "url": "https://www.ensembl.org/id/ENSGALP00010023502.1" } ] } }, { "isoform_ac": "A0A8V0YXZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7/entry#A0A8V0YXZ6-1", "sequence": { "sequence": "MAMSDVSESVVLSNGSILSNATSPDNQRTQQMLSQCCHPCPYHHSLSNHNNRQECHSVVSSSAPSPMTSCCMQPHTEYSASICRKHTPIYQPACCLQPSPSFCLHHQWPDHFQHQPVQQHIARIRPARPFKLPKSYAALIADWPVVVLGMCTVLIVVCALVGILVPDLPDFSDPLLGFEPRGTAIGQRLVTWNNMVKNTGYKATLANYPFKYADEQAKSHQDDRWSDDHYEREKRQAEWNFHKDTFFCDIPSDRYSRVVFTSTEGENLWNLNAIKSMCNVDNLRIRSHSQFGDLCQRATAASCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKYYYNGTLGPDCWDMNAKRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFLSPKTADYVLPALKYSMLFSPTEKGESMMSIYLDNFENWNSSDGVTTVTGIEFGIKHSLFQDYLLMDTVYPAIAIVIVLLVMCVYTKSMFITLMTMFAIISSLIVSYFLYRVVFNFEFFPFMNLTALIILVGIGADDAFVLCDVWNYTKFDKPHAGTSETVSITLQHAALSMFVTSFTTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVVVLHERYLLNIFSCFKKPQQRVYNNKNCWTVLCQMFHKVIFAVSEASRIFFEKVLPCIVIKFRYIWLFWFLALTVGGAYIVCVNPKMKLPSLELSEFQVFRSSHPFERYDAEYKKLFMFERVHHGEELHMPITVIWGVMPEDNGDPLNPKSKGKLQLDSSFNIASPASQVWILRFCQKLRNQTFFYQTEEQDFTSCFIETFKQWMENQDCDEPSLYPCCSHWSFPYKQEVFELCIKRAIMELERSTGYHLDSKTPGPRFDLNDTIRAVVLEFQSTYLFTLAYEKMHQFYKEVDSWISSELSSAPEGLSNGWFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLGPQGTCGQIPLPKKLRCNAFSQTFSGAQGGRGQNKSHPISKYQLDSRGQKPEMEHEHYELEPLASQAGICNPAEKVTYEETHICSELFSSRSQNTCMPMHSVYNSEVSKSIKNVASSAVLQSSIDQRALCPLFSQNRQCSCPDPYKQVTVKWSPHSCQQLSDPFCYQCSPSPGAVQIQSSVTPINTLQQTTEGYVHPVQHVLHCSCLQGRLKRTMTQNSLPKNFFLQSVQQLQAHQRVNRTDSHAHQNPEENIRTVPKVMSSSQFLCRNAGPLIVHCSECENSVPNNQKGLCQKADKCDEKGGTEANGVESKKASMSKQKKKAESKIDQCSLQNDQVLKGDQAAKKHLLNRSAGEAHCEGCHENSHCCSTAVVVKCNSVDCQMPNIEANVPPMLMRPELSNESLLIKTL", "length": 1498, "header": "tr|A0A8V0YXZ6-1|A0A8V0Z4P7_CHICK Computationally mapped isoform of Protein dispatched homolog 1 OS=Gallus gallus OX=9031 GN=DISP1 PE=3 SV=1 CANONICAL=A0A8V0Z4P7-1" }, "locus": { "chromosome": "3", "start_pos": 17609186, "end_pos": 17577056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040512.1", "url": "https://www.ensembl.org/id/ENSGALT00010040512.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023517.1", "url": "https://www.ensembl.org/id/ENSGALP00010023517.1" } ] } }, { "isoform_ac": "A0A8V0Z4M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7/entry#A0A8V0Z4M3-1", "sequence": { "sequence": "MIPLVAYSHRFLHLSRKEEQSLCLLKSHILYLKSLYSRVKLRPARPFKLPKSYAALIADWPVVVLGMCTVLIVVCALVGILVPDLPDFSDPLLGFEPRGTAIGQRLVTWNNMVKNTGYKATLANYPFKYADEQAKSHQDDRWSDDHYEREKRQAEWNFHKDTFFCDIPSDRYSRVVFTSTEGENLWNLNAIKSMCNVDNLRIRSHSQFGDLCQRATAASCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKYYYNGTLGPDCWDMNAKRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFLSPKTADYVLPALKYSMLFSPTEKGESMMSIYLDNFENWNSSDGVTTVTGIEFGIKHSLFQDYLLMDTVYPAIAIVIVLLVMCVYTKSMFITLMTMFAIISSLIVSYFLYRVVFNFEFFPFMNLTALIILVGIGADDAFVLCDVWNYTKFDKPHAGTSETVSITLQHAALSMFVTSFTTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVVVLHERYLLNIFSCFKKPQQRVYNNKNCWTVLCQMFHKVIFAVSEASRIFFEKVLPCIVIKFRYIWLFWFLALTVGGAYIVCVNPKMKLPSLELSEFQVFRSSHPFERYDAEYKKLFMFERVHHGEELHMPITVIWGVMPEDNGDPLNPKSKGKLQLDSSFNIASPASQVWILRFCQKLRNQTFFYQTEEQDFTSCFIETFKQWMENQDCDEPSLYPCCSHWSFPYKQEVFELCIKRAIMELERSTGYHLDSKTPGPRFDLNDTIRAVVLEFQSTYLFTLAYEKMHQFYKEVDSWISSELSSAPEGLSNGWFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLGPQGTCGQIPLPKKLRCNAFSQTFSGAQGGRGQNKSHPISKYQLDSRGQKPEMEHEHYELEPLASQAGICNPAEKVTYEETHICSELFSSRSQNTCMPMHSVYNSEVSKSIKNVASSAVLQSSIDQRALCPLFSQNRQCSCPDPYKQVTVKWSPHSCQQLSDPFCYQCSPSPGAVQIQSSVTPINTLQQTTEGYVHPVQHVLHCSCLQGRLKRTMTQNSLPKNFFLQSVQQLQAHQRVNRTDSHAHQNPEENIRTVPKVMSSSQFLCRNAGPLIVHCSECENSVPNNQKGLCQKADKCDEKGGTEANGVESKKASMSKQKKKAESKIDQCSLQNDQVLKGDQAAKKHLLNRSAGEAHCEGCHENSHCCSTAVVVKCNSVDCQMPNIEANVPPMLMRPELSNESLLIKTL", "length": 1415, "header": "tr|A0A8V0Z4M3-1|A0A8V0Z4M3_CHICK Computationally mapped isoform of Protein dispatched homolog 1 OS=Gallus gallus OX=9031 GN=DISP1 PE=3 SV=1 CANONICAL=A0A8V0Z4P7-1" }, "locus": { "chromosome": "3", "start_pos": 17601480, "end_pos": 17577056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040489.1", "url": "https://www.ensembl.org/id/ENSGALT00010040489.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023499.1", "url": "https://www.ensembl.org/id/ENSGALP00010023499.1" } ] } }, { "isoform_ac": "A0A8V0Z4N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7/entry#A0A8V0Z4N4-1", "sequence": { "sequence": "MAMSDVSESVVLSNGSILSNATSPGIVATNDGDVAFQQLPSKETPRAKANPNGCLQFNGTIKPSFLPLDNQRTQQMLSQCCHPCPYHHSLSNHNNRQECHSVVSSSAPSPMTSCCMQPHTEYSASICRKHTPIYQPACCLQPSPSFCLHHQWPDHFQHQPVQQHIARIRWRKQRETYFSFDGKERGPARPFKLPKSYAALIADWPVVVLGMCTVLIVVCALVGILVPDLPDFSDPLLGFEPRGTAIGQRLVTWNNMVKNTGYKATLANYPFKYADEQAKSHQDDRWSDDHYEREKRQAEWNFHKDTFFCDIPSDRYSRVVFTSTEGENLWNLNAIKSMCNVDNLRIRSHSQFGDLCQRATAASCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKYYYNGTLGPDCWDMNAKRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFLSPKTADYVLPALKYSMLFSPTEKGESMMSIYLDNFENWNSSDGVTTVTGIEFGIKHSLFQDYLLMDTVYPAIAIVIVLLVMCVYTKSMFITLMTMFAIISSLIVSYFLYRVVFNFEFFPFMNLTALIILVGIGADDAFVLCDVWNYTKFDKPHAGTSETVSITLQHAALSMFVTSFTTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVVVLHERYLLNIFSCFKKPQQRVYNNKNCWTVLCQMFHKVIFAVSEASRIFFEKVLPCIVIKFRYIWLFWFLALTVGGAYIVCVNPKMKLPSLELSEFQVFRSSHPFERYDAEYKKLFMFERVHHGEELHMPITVIWGVMPEDNGDPLNPKSKGKLQLDSSFNIASPASQVWILRFCQKLRNQTFFYQTEEQDFTSCFIETFKQWMENQDCDEPSLYPCCSHWSFPYKQEVFELCIKRAIMELERSTGYHLDSKTPGPRFDLNDTIRAVVLEFQSTYLFTLAYEKMHQFYKEVDSWISSELSSAPEGLSNGWFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLGPQGTCGQIPLPKKLRCNAFSQTFSGAQGGRGQNKSHPISKYQLDSRGQKPEMEHEHYELEPLASQAGICNPAEKVTYEETHICSELFSSRSQNTCMPMHSVYNSEVSKSIKNVASSAVLQSSIDQRALCPLFSQNRQCSCPDPYKQVTVKWSPHSCQQLSDPFCYQCSPSPGAVQIQSSVTPINTLQQTTEGYVHPVQHVLHCSCLQGRLKRTMTQNSLPKNFFLQSVQQLQAHQRVNRTDSHAHQNPEENIRTVPKVMSSSQFLCRNAGPLIVHCSECENSVPNNQKGLCQKADKCDEKGGTEANGVESKKASMSKQKKKAESKIDQCSLQNDQVLKGDQAAKKHLLNRSAGEAHCEGCHENSHCCSTAVVVKCNSVDCQMPNIEANVPPMLMRPELSNESLLIKTL", "length": 1559, "header": "tr|A0A8V0Z4N4-1|A0A8V0Z4N4_CHICK Computationally mapped isoform of Protein dispatched homolog 1 OS=Gallus gallus OX=9031 GN=DISP1 PE=3 SV=1 CANONICAL=A0A8V0Z4P7-1" }, "locus": { "chromosome": "3", "start_pos": 17609186, "end_pos": 17577056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040504.1", "url": "https://www.ensembl.org/id/ENSGALT00010040504.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023509.1", "url": "https://www.ensembl.org/id/ENSGALP00010023509.1" } ] } }, { "isoform_ac": "A0A8V0Z4P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7/entry#A0A8V0Z4P7-1", "sequence": { "sequence": "MGNEQVILWTITAGSKFTSERSRFVADGSGRTAQPGAVHLAEWNISCLSRTWSMAMSDVSESVVLSNGSILSNATSPGIVATNDGDVAFQQLPSKETPRAKANPNGCLQFNGTIKPSFLPLDNQRTQQMLSQCCHPCPYHHSLSNHNNRQECHSVVSSSAPSPMTSCCMQPHTEYSASICRKHTPIYQPACCLQPSPSFCLHHQWPDHFQHQPVQQHIARIRPARPFKLPKSYAALIADWPVVVLGMCTVLIVVCALVGILVPDLPDFSDPLLGFEPRGTAIGQRLVTWNNMVKNTGYKATLANYPFKYADEQAKSHQDDRWSDDHYEREKRQAEWNFHKDTFFCDIPSDRYSRVVFTSTEGENLWNLNAIKSMCNVDNLRIRSHSQFGDLCQRATAASCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKYYYNGTLGPDCWDMNAKRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFLSPKTADYVLPALKYSMLFSPTEKGESMMSIYLDNFENWNSSDGVTTVTGIEFGIKHSLFQDYLLMDTVYPAIAIVIVLLVMCVYTKSMFITLMTMFAIISSLIVSYFLYRVVFNFEFFPFMNLTALIILVGIGADDAFVLCDVWNYTKFDKPHAGTSETVSITLQHAALSMFVTSFTTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVVVLHERYLLNIFSCFKKPQQRVYNNKNCWTVLCQMFHKVIFAVSEASRIFFEKVLPCIVIKFRYIWLFWFLALTVGGAYIVCVNPKMKLPSLELSEFQVFRSSHPFERYDAEYKKLFMFERVHHGEELHMPITVIWGVMPEDNGDPLNPKSKGKLQLDSSFNIASPASQVWILRFCQKLRNQTFFYQTEEQDFTSCFIETFKQWMENQDCDEPSLYPCCSHWSFPYKQEVFELCIKRAIMELERSTGYHLDSKTPGPRFDLNDTIRAVVLEFQSTYLFTLAYEKMHQFYKEVDSWISSELSSAPEGLSNGWFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLGPQGTCGQIPLPKKLRCNAFSQTFSGAQGGRGQNKSHPISKYQLDSRGQKPEMEHEHYELEPLASQAGICNPAEKVTYEETHICSELFSSRSQNTCMPMHSVYNSEVSKSIKNVASSAVLQSSIDQRALCPLFSQNRQCSCPDPYKQVTVKWSPHSCQQLSDPFCYQCSPSPGAVQIQSSVTPINTLQQTTEGYVHPVQHVLHCSCLQGRLKRTMTQNSLPKNFFLQSVQQLQAHQRVNRTDSHAHQNPEENIRTVPKVMSSSQFLCRNAGPLIVHCSECENSVPNNQKGLCQKADKCDEKGGTEANGVESKKASMSKQKKKAESKIDQCSLQNDQVLKGDQAAKKHLLNRSAGEAHCEGCHENSHCCSTAVVVKCNSVDCQMPNIEANVPPMLMRPELSNESLLIKTL", "length": 1595, "header": "tr|A0A8V0Z4P7-1|A0A8V0Z4P7_CHICK Isoform 1 of Protein dispatched homolog 1 OS=Gallus gallus OX=9031 GN=DISP1 PE=3 SV=1 CANONICAL=A0A8V0Z4P7-1" }, "locus": { "chromosome": "3", "start_pos": 17629496, "end_pos": 17577056, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040514.1", "url": "https://www.ensembl.org/id/ENSGALT00010040514.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023519.1", "url": "https://www.ensembl.org/id/ENSGALP00010023519.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1075, "start_aa": "Thr", "end_pos": 1075, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1075", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A061I2S8-1", "protein_name": "Protein dispatched homolog 1", "gene_name": "Disp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVISGSDSVLLSNGSISTSTTNPCPLTPSDGDQLTPREAPRTKASSNGCLQLNGTVKSSFLPLDHQRAPQTPAQCCQPCPYHPPVTSHSSHQEGHPQPGPAASSALASCCMQPHSEYSASLCPNHSPVYQAAHCLQPSPSFCLHHPWPDHFQHQPAQQHLAILRPSRPFKFPRSYAALLADWPVVVLGMCTLLIVVCALVGVLVPELPDFSDPLLGFEPRGTAIGQRLVTWNNMMKNTGYKATLANYPYKYAEEQAKSHRDDRWSDDHHDRERREVDWDFQKDSFFCDAPSDGYSRVVFASAGGETLWNLPAIKSMCDVDNSRIRSHAQFSDLCQRTTAVSCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKHYQNGTLGPDCWDKAARRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFLTPKTADYAMPALKYSMLFSPTEKGESMMNIYLDNFENWNSSDGITTVTGIEFGIKHSLFQGYLLMDTVYPAIAIVIVLLIMCVYTKSMFITLMAMFAVISSLIVSYFLYRVVFNFEFFPFMNLTALIILVGIGADDAFVLCDVWNYTKFDKPRADTSEAVSITLQHAALSMFVTSFTTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVIVLHERYLLNIFSCFRKPQPQAYDKSCWAVACQKCRKVLFAISEASRIFFEKVLPCIVIKFRYLWLIWFLALTIGGAYVVCINPKMKLPSLELSEFQVFRSSHPFERYDAEFKKLFMFERVHHGEELHMPITVIWGVSPEDSGNPLNPKSKGKLTLDSTFNIASPASQAWILHFCQKLRNQTFFYQTEQQDFTSCFIETFKQWMENQDCDEPALYPCCSHCSFPYKQEVFELCIKKAIMELDRSTGYHLNNKTPGPRFDVNDTIRAVVLEFQSTFLFTLAYEKMQQFYKEVDSWISSELSSAPEGLSHGWFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTWNIILSLYAIISIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLVMCISWAFATFFFQCMCRCLGPQGTCGQIPLPKKLQCGAFSHTLSASPGDRGPSKTHTANSYRVDARDPRSELEHEFYELQPLASHSCSASEKNTFDEPHICSAFSNGQAKTLGLPVPLTYNSELTKSPRNEPGSALLQPCLEQGAMCHFSLNQRCSCPNAYMHLKYGPRSCQQVGDSLCQQCASTASSFVQIQNVVAPLKTTHQAAEVLMHPIRHMLPPGMQNSLPRNFFLHPVQCIQAQEQLDDSSIHSLQSMDEHLPRTAEPLLPVSRSPEAFQRACCHPENNQRGLCKSRDTGDTEGNGGTKTKVSSLPNQADKAEKKVEPSQLQTDENVNSEHLNHNEPKFIFSHLLGETDCRSCPSSPQSCRSIVRLKCDSTDCTMPNLEASVPAVPAHSELSGESLLIKTL", "length": 1516 }, "evidence": [ { "id": "A0A8V0Z4P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4P7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LKD4-1", "protein_name": "Protein dispatched homolog 1", "gene_name": "Disp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLRAASPRTGEAGEARGSRRGGRAGTPGTKNSGMAVISGSDSVLLSNGSISTSTTNPSPLTPSDGDLTAQQLAPRETPRTKASPNGCLQLNGTVKSSFLPLDNQRTPQTALCCHPCPYHHPVTSHTSHQECHPEAGLAASSALTSGCIQPHSEYSASLCPNHSPVYQAAHCRQPSPSLCLHHPWPDHFQHQPVRQHLAIIGPSRPFRFPRSYAALLADWPVVVLGLCTLLIVVCALVGVLVPELPDFSDPLLGFEPRGTAIGQRLVTWNNMMKNTGYKATLANYPYKYAEEQAKSRRDDRWSGDHHERERREVDWNFQKDSFFCDVPSDGYSRVVFASAGGETLWNLPAIKSMCDVDNSRIRSHPQFSDLCQRTTAVSCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKHYQNGTLGPDCWDKAARRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFMTSKTADYAVPALKYSMLFSPTEKGESMMNIYLDNFENWNSSDGITTVTGIEFGIKHSLFQDYLLMDTVYPAIAIAIVLLIMCVYTKSVFITLMTMFAIISSLIVSYFLYRVVFNFEFFPFMNLTALIILVGIGADDAFVLCDVWNYTKSDKPRAETSEAVSVTLQHAALSMFVTSFTTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVIVLHERYLLNIFTCFRKPQPQAYHKSCWTVLCRKGRKALFAISEASRIFFEKVLPCIVIKFRYLWLVWFLALTVGGAYIVCINPKMKLPSLELSEFQVFRSSHPFERYDAEFKKLFMFERVHHGEELHMPITVIWGVSPEDSGDPLNPKSKGELTLDSTFNIASPASQAWILHFCQKLRNQTFFHQTEQQDFTSCFIETFKQWMENQDCDEPALYPCCSHCSFPYKQEVFELCIKKAIMELDRSTGYHLNNKTPGPRFDINDTIRAVVLEFQSTFLFTLAYEKMQQFYKEVDSWISHELSSAPEGLSHGWFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTCNIIISLYAIASIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLGRMGSAIAVAALTTFVAGAMMMPSTVLAYTQLGTFMMLVMCVSWAFATFFFQCLCRCLGPQGTCGQIPLPKKLQCSAFSHTSAARPGGRAPGKATNAYSVDARGQKSELEHELYELQPLGSHSCTSSDMTAYEGPCICSEFFNGQAKNLRMPMSAAYSSELTKSPRSEPGSALLQPCLEQDTMCHFSLNPRCNCPNAYTHRKYGLPEIHCQQMGDSLCHKCASTAGSFVQIQNAAAPLKATHHAAEGLLHPVQHMLPPGMQNSQSRNFFLHPVQHFQAQESLGPTSTRGRENTDERPPRTAEPPPAGASRSSESFQRACCNPENNQRRLCKSRDSGDTEGSGGTETKVCGLANQTDKVEKEVKPSLLQTDEIVNSEQLNHDEPKLIFSHLIREAGCRPCPDRPQGCRSLRLKCGSTDCQAPDLEANVPAVPTHSDLSVSGESLLIKTLQ", "length": 1556 }, "evidence": [ { "id": "A0A8V0Z4P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4P7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TDN0-1", "protein_name": "Protein dispatched homolog 1", "gene_name": "Disp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVISGSDSVLLSNGSISTSTSNPSPLSPSDGDLPAQHLGPRETPRTKASPNGCLQLNGTVKSSFLPLDNQRTPQTPTQCCHPCPYHHPVSSHSNHQECHPEAGLAASPALASCRMQPHSEYSASLCPNHSPVYQAAHCLQPSPSFCLHHPWPDHFQHQPVRQHLTIIRPSRPFKFPRSYAALLADWPVVVLGMCTLLIVVCALVGVLVPELPDFSDPLLGFEPRGTTIGQRLVTWNNMMRNTGYKATLANYPYKYAEEQARSHRDDRWSDDHHERERREVDWNFQKDSFFCDVPSDGYSRVVFASAGGETLWNLPAIKSMCDVDNSRIRSHPQFSDLCQRTTAVSCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKHYQNGTLGPDCWDKAARRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFMTPKTADYAVPALKYSMLFSPTEKGESMMNIYLDNFENWNSSDGITTVTGIEFGIKHSLFQDYLLMDTVYPAIAIAIVLLIMCVYTKSMFITLMTMFAIISSLIVSYFLYRVVFNFEFFPFMNLTALIILVGIGADDAFVLCDVWNYTKFDKPRAETSEAVSVTLQHAALSMFVTSFTTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVIVLHERYLLNIFTCFRKPQPQAYDKSCWAVLCQKCRRVLFAVSEASRIFFEKVLPCIVIKFRYLWLIWFLALTVGGAYIVCVNPKMKLPSLELSEFQVFRSSHPFERYDAEFKKLFMFERVHHGEELHMPITVIWGVSPEDSGDPLNPKSKGELTLDSTFNIASPASQAWILHFCQKLRNQTFFHQTEQQDFTSCFIETFKQWMENQDCDEPALYPCCSHCSFPYKQEVFELCIKKAIMELDRSTGYHLNNKTPGPRFDINDTIRAVVLEFQSTFLFTLAYEKMQQFYKEVDSWISHELSSAPEGLSRGWFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTWNIIISLYAIVSIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRMGSAIAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLVMCVSWAFATFFFQCLCRCLGPQGTCGQIPFPTKLQCSPFSHTLSARPGDRGPSKTHAASAYSVDARGQKSQLEHEFYELQPLASHSCTSSEKTTYEEPHTCSEFFNGQAKNLRMPVPAAYSSELTKSPSSEPGSALLQSCLEQDTVCHFSLNPRCNCRDAYTHLQYGLPEIHCQQMGDSLCHKCASTAGGFVQIQSSVAPLKASHQAAEGLLHPAQHMLPPGMQNSRPRNFFLHSVQHFQAQENLGRTSTHSTDERLPRTAELSPPPSDSRSTESFQRACCHPENNQRRLCKSRDPGDTEGSGGTKSKVSGLPNQTDKEEKQVEPSLLQTDETVNSEHLNHNESNFTFSHLPGEAGCRSCPNSPQSCRSIMRSKCGTEDCQTPNLEANVPAVPTHSDLSGESLLIKTL", "length": 1521 }, "evidence": [ { "id": "A0A8V0Z4P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4P7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96F81-1", "protein_name": "Protein dispatched homolog 1", "gene_name": "DISP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMSNGNNDFVVLSNSSIATSAANPSPLTPCDGDHAAQQLTPKEATRTKVSPNGCLQLNGTVKSSFLPLDNQRMPQMLPQCCHPCPYHHPLTSHSSHQECHPEAGPAAPSALASCCMQPHSEYSASLCPNHSPVYQTTCCLQPSPSFCLHHPWPDHFQHQPVQQHIANIRPSRPFKLPKSYAALIADWPVVVLGMCTMFIVVCALVGVLVPELPDFSDPLLGFEPRGTAIGQRLVTWNNMVKNTGYKATLANYPFKYADEQAKSHRDDRWSDDHYEREKREVDWNFHKDSFFCDVPSDRYSRVVFTSSGGETLWNLPAIKSMCNVDNSRIRSHPQFGDLCQRTTAASCCPSWTLGNYIAILNNRSSCQKIVERDVSHTLKLLRTCAKHYQNGTLGPDCWDMAARRKDQLKCTNVPRKCTKYNAVYQILHYLVDKDFMTPKTADYATPALKYSMLFSPTEKGESMMNIYLDNFENWNSSDGVTTITGIEFGIKHSLFQDYLLMDTVYPAIAIVIVLLVMCVYTKSMFITLMTMFAIISSLIVSYFLYRVVFHFEFFPFMNLTALIILVGIGADDAFVLCDVWNYTKFDKPHAETSETVSITLQHAALSMFVTSFTTAAAFYANYVSNITAIRCFGVYAGTAILVNYVLMVTWLPAVVVLHERYLLNIFTCFKKPQQQIYDNKSCWTVACQKCHKVLFAISEASRIFFEKVLPCIVIKFRYLWLFWFLALTVGGAYIVCINPKMKLPSLELSEFQVFRSSHPFERYDAEYKKLFMFERVHHGEELHMPITVIWGVSPEDNGNPLNPKSKGKLTLDSSFNIASPASQAWILHFCQKLRNQTFFYQTDEQDFTSCFIETFKQWMENQDCDEPALYPCCSHWSFPYKQEIFELCIKRAIMELERSTGYHLDSKTPGPRFDINDTIRAVVLEFQSTYLFTLAYEKMHQFYKEVDSWISSELSSAPEGLSNGWFVSNLEFYDLQDSLSDGTLIAMGLSVAVAFSVMLLTTWNIIISLYAIISIAGTIFVTVGSLVLLGWELNVLESVTISVAVGLSVDFAVHYGVAYRLAPDPDREGKVIFSLSRVGSAMAMAALTTFVAGAMMMPSTVLAYTQLGTFMMLIMCISWAFATFFFQCMCRCLGPQGTCGQIPLPKKLQCSAFSHALSTSPSDKGQSKTHTINAYHLDPRGPKSELEHEFYELEPLASHSCTAPEKTTYEETHICSEFFNSQAKNLGMPVHAAYNSELSKSTESDAGSALLQPPLEQHTVCHFFSLNQRCSCPDAYKHLNYGPHSCQQMGDCLCHQCSPTTSSFVQIQNGVAPLKATHQAVEGFVHPITHIHHCPCLQGRVKPAGMQNSLPRNFFLHPVQHIQAQEKIGKTNVHSLQRSIEEHLPKMAEPSSFVCRSTGSLLKTCCDPENKQRELCKNRDVSNLESSGGTENKAGGKVELSLSQTDASVNSEHFNQNEPKVLFNHLMGEAGCRSCPNNSQSCGRIVRVKCNSVDCQMPNMEANVPAVLTHSELSGESLLIKTL", "length": 1524 }, "evidence": [ { "id": "A0A8V0Z4P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4P7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VNJ5-1", "protein_name": "Protein dispatched", "gene_name": "disp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLCFDSERMNWYYHVLARRPYLVVVSIAVYCVACIIVALVLNKLPDFSDPTLGFETRGTKIGERLTAWYNLLQETDHHGALFSNPSDLWERRRVEQGYVETKLHPNHRRRKNKHKNRNKNKRRKEQNQSSHEHHDVAQKMMQFKKRLKATSSPSPNLGFDTWIGDSGVFRDYEITNDSASSSLEPTRRTEQIEYGHNTTSVDEEEHQQRVQTKKSTWRLLKQAATLPTDGWADMHRRQPIEGFFCDSSPRKEYSHFVVQRIGPNATDSLFDLNGLLAMCQLQDQITEVPSYRAFCEPEMLTTECCRPWSLPNYAAMLANKSSCFDLTTEDVTSLHTLLLGCYEYFHDLKMDNHCNEIPHCRAPEECKRLNIVFNVLNFLTDFSFIKSNDSNVYLKYAMIFIPVAQSNRLLPLFHEWEDVELINELVEVVAMDLGLENELFNELLLTDVWLVSLGGTFVMASVWLYTGSAFITLMSCVAICFSLGLAYFFYAIVLEFEFFPYMNLLAVVVIIGIGADDVFLFLKIWHCVLTERFSNRCTLTTQSQSALPTLENSDHTESLENIMALTMRHAAASMFVTSLTTAGAFYASYSSSITAIKCFGIFAGTVVVTNYLLMITWLPASVSIMERLFATRMSCHHPMSIKLIHACKKSINRFCQMFEECITKSIMNYAYLWLLIFGALGASSAVIVFWYPGLQLPEKSHFQLFVSKHPFEVYSSLKQQFWFEKPLQAYENFKMHMHFVWGVQAVDDGDYTNPNSYGHLHYDNNFNVSSRPAQLWILDFCQSVRQQPFYKETLGMLLPNCFIENLIDYMKRRCIDDMDSTRKDRSPCCDAQFPFEPHIFEYCLPQSISNMYDTTFFRPGVAGPKFAEAPRLETEDYLGMSGNESAEYSTNGSFTPLLVKALVIEFESNVAYSTIYANIRQFYESVEHWFQMQLKTAPPELQGGWFTSDLKFYNVQDTLSHDTFVAICLAMAASLAVLLCFTVNILISIYAVLTVSLSIFNTVAVLILLGWQLNILESIAVSTAIGLAVDFSLHYGIHYRMSPVKERLAATQFVLSRIIGPTVMAATTTGLAGGIMMASNILPYIQIGVFLVVVMIVSWFYATFFLMSLLRVAGPQHGFLELKWPLWSKRSSGSSKFYERKPSQVIASEQLLTPTSSAIVELANSETHELESLNSNSLIKTISGIESAHALSSLPRDFEHSFQTMHECKYQTYPSTSN", "length": 1218 }, "evidence": [ { "id": "A0A8V0Z4P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4P7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "molecular carrier activity", "id": "GO:0140104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140104", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1220, "end_pos": 1222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1425, "end_pos": 1427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1536, "end_pos": 1538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1587, "end_pos": 1589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 678, "end_pos": 680, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" }, { "start_pos": 969, "end_pos": 971, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P7" }, { "id": "PS50156", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SSD", "eco_id": "ECO_0000259", "start_pos": 576, "end_pos": 710, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1075 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 1220, "end_pos": 1222 }, { "start_pos": 1425, "end_pos": 1427 }, { "start_pos": 1536, "end_pos": 1538 }, { "start_pos": 1587, "end_pos": 1589 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 443, "end_pos": 445 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 528, "end_pos": 530 }, { "start_pos": 611, "end_pos": 613 }, { "start_pos": 634, "end_pos": 636 }, { "start_pos": 678, "end_pos": 680 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 888, "end_pos": 890 }, { "start_pos": 969, "end_pos": 971 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z465-1", "uniprot_ac": "A0A8V0Z465", "uniprot_id": "A0A8V0Z465_CHICK", "mass": { "chemical_mass": 47582.0, "monoisotopic_mass": 47582.0 }, "refseq": { "ac": "NP_001264520", "name": "clusterin-associated protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264520" }, "gene_names": [ { "name": "CLUAP1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465" } ] }, { "name": "CLUAP1", "type": "synonym", "evidence": [ { "id": "NP_001264520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264520" } ] } ], "protein_names": [ { "name": "Clusterin associated protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z465", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465/entry#names_and_taxonomy" } ] }, { "name": "clusterin-associated protein 1", "type": "synonym", "evidence": [ { "id": "NP_001264520", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264520" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEL01010398.1, CR386534.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000257.1. On Apr 12, 2013 this sequence version replaced XP_423754.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001264520", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264520" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z465", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLUAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465", "locus": { "chromosome": "14", "start_pos": 12774290, "end_pos": 12830835, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016700", "url": "https://www.ensembl.org/id/ENSGALG00010016700" } ] } } ], "crossref": [ { "id": "A0A8V0Z465", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z465", "database": "AlphaFoldDB", "categories": [] }, { "id": "426077", "url": "https://www.ncbi.nlm.nih.gov/gene/426077", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:426077", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426077", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RKVYGNM", "url": "https://omabrowser.org/oma/group/RKVYGNM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXI5", "url": "https://www.orthodb.org/?gene=A0A8V0YXI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXJ0", "url": "https://www.orthodb.org/?gene=A0A8V0YXJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YZ14", "url": "https://www.orthodb.org/?gene=A0A8V0YZ14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z465", "url": "https://www.orthodb.org/?gene=A0A8V0Z465", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21547", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21547", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21547:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21547:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620924", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264520", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264520", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YXI5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YZ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z465", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z465-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYRDVRNLTEMLRALGYPRLVSMENFHAPNFALVAELLLWLVRRYEPQSDIPPDVETEQDRVFFIKAVAQFMATKAHIKLNTKKLYQADGYAVRELLKVTSVLYSAMNTEGMERTDITEEDSSKFKFDLGSKIADLKAARQLASEITSKGANLYDLLGKEVELREARTESIARPLEINEAEKMMKVAIDCVLEEVQKTKDMLSNVALDEANLEAKIEKRKSELERSQKRLQTLQSVRPAFMDEYEKIEEQLQKQYTSYLEKFHNLTYLEQLLDDQHRTEQEMFEEAANMLRLMQNRLKEEEQRLLKSGSNDDSDMEIQEDEGSDSEVEDRQFRKQRTALDTLVPGRAGARIVGAMQGGDTEEDEESGDSEIDLDDDEDEEEDVEDDSMEISPSKSSHRAKKPEPLEESDNDF", "length": 413, "header": "tr|A0A8V0Z465-1|A0A8V0Z465_CHICK Isoform 1 of Clusterin associated protein 1 OS=Gallus gallus OX=9031 GN=CLUAP1 PE=3 SV=1 CANONICAL=A0A8V0Z465-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465/entry#A0A8V0YXI5-1", "sequence": { "sequence": "MSYRDVRNLTEMLRALGYPRLVSMENFHAPNFALVAELLLWLVRRYEPQSDIPPDVETEQDRVFFIKAVAQFMATKAHIKLNTKKLYQADGYAVRELLKVTSVLYSAMNTEGMERTDITEEDSSKFKFDLGSKIADLKAARQLASEITSKGANLYDLLGKEVELREARTESIARPLEINEAEKMMKVAIDCVLEEVQKTKDMLSNVALDEANLEAKIEKRKSELERSQKRLQTLQSVRPAFMDEYEKIEEQLQKQYTSYLEKFHNLTYLEQLLDDQHRTEQEMFEEAANMLRLMQNRLKEEEQRLLKSGSNDDSDMEIQEDEGSDSEVEDRQFRKQRTALDTLVPGRAGARIVGAMQGGDTEEDGRAAPAQPGKHGIITKAQEESGDSEIDLDDDEDEEEDVEDDSMEISPSKSSHRAKKPEPLEESDNDF", "length": 431, "header": "tr|A0A8V0YXI5-1|A0A8V0Z465_CHICK Computationally mapped isoform of Clusterin associated protein 1 OS=Gallus gallus OX=9031 GN=CLUAP1 PE=3 SV=1 CANONICAL=A0A8V0Z465-1" }, "locus": { "chromosome": "14", "start_pos": 12830796, "end_pos": 12775090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040263.1", "url": "https://www.ensembl.org/id/ENSGALT00010040263.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023345.1", "url": "https://www.ensembl.org/id/ENSGALP00010023345.1" } ] } }, { "isoform_ac": "A0A8V0YXJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465/entry#A0A8V0YXJ0-1", "sequence": { "sequence": "MSYRDVRNLTEMLRALGYPRLVSMENFHAPNFALVAELLLWLVRRYEPQSDIPPDVETEQDRVFFIKAVAQFMATKAHIKLNTKKLYQADGYAVRELLKVTSVLYSAMNTEGMERTDITEEDSSKFKFDLGSKIADLKAARQLASEITSKGANLYDLLGKEVELREARTESIARPLEINEAEKMMKVAIDCVLEEVQKTKDMLSNVALDEANLEAKIEKRKSELERSQKRLQTLQSVRPAFMDEYEKIEEQLQKQYTSYLEKFHNLTYLEQLLDDQHRTEQEMFEEAANMLRLMQNRLKEEEQRLLKSGRRAGARIVGAMQGGDTEEDEESGDSEIDLDDDEDEEEDVEDDSMEISPSKSSHRAKKPEPLEESDNDF", "length": 377, "header": "tr|A0A8V0YXJ0-1|A0A8V0Z465_CHICK Computationally mapped isoform of Clusterin associated protein 1 OS=Gallus gallus OX=9031 GN=CLUAP1 PE=3 SV=1 CANONICAL=A0A8V0Z465-1" }, "locus": { "chromosome": "14", "start_pos": 12830796, "end_pos": 12775090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040270.1", "url": "https://www.ensembl.org/id/ENSGALT00010040270.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023350.1", "url": "https://www.ensembl.org/id/ENSGALP00010023350.1" } ] } }, { "isoform_ac": "A0A8V0YZ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465/entry#A0A8V0YZ14-1", "sequence": { "sequence": "MSYRDVRNLTEMLRALGYPRLVSMENFHAPNFALVAELLLWLVRRYEPQSDIPPDVETEQDRVFFIKAVAQFMATKAHIKLNTKKLYQADGYAVRELLKVTSVLYSAMNTEGMERTDITEEDSSKFKFDLGSKIADLKAARQLASEITSKGANLYDLLGKEVELRELFLHVVGIGAVWKIVMHEEARTESIARPLEINEAEKMMKVAIDCVLEEVQKTKDMLSNVALDEANLEAKIEKRKSELERSQKRLQTLQSVRPAFMDEYEKIEEQLQKQYTSYLEKFHNLTYLEQLLDDQHRTEQEMFEEAANMLRLMQNRLKEEEQRLLKSGSNDDSDMEIQEDEGSDSEVEDRQFRKQRTALDTLVPGRAGARIVGAMQGGDTEEDEESGDSEIDLDDDEDEEEDVEDDSMEISPSKSSHRAKKPEPLEESDNDF", "length": 432, "header": "tr|A0A8V0YZ14-1|A0A8V0Z465_CHICK Computationally mapped isoform of Clusterin associated protein 1 OS=Gallus gallus OX=9031 GN=CLUAP1 PE=3 SV=1 CANONICAL=A0A8V0Z465-1" }, "locus": { "chromosome": "14", "start_pos": 12830796, "end_pos": 12775090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040274.1", "url": "https://www.ensembl.org/id/ENSGALT00010040274.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023354.1", "url": "https://www.ensembl.org/id/ENSGALP00010023354.1" } ] } }, { "isoform_ac": "A0A8V0Z465-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465/entry#A0A8V0Z465-1", "sequence": { "sequence": "MSYRDVRNLTEMLRALGYPRLVSMENFHAPNFALVAELLLWLVRRYEPQSDIPPDVETEQDRVFFIKAVAQFMATKAHIKLNTKKLYQADGYAVRELLKVTSVLYSAMNTEGMERTDITEEDSSKFKFDLGSKIADLKAARQLASEITSKGANLYDLLGKEVELREARTESIARPLEINEAEKMMKVAIDCVLEEVQKTKDMLSNVALDEANLEAKIEKRKSELERSQKRLQTLQSVRPAFMDEYEKIEEQLQKQYTSYLEKFHNLTYLEQLLDDQHRTEQEMFEEAANMLRLMQNRLKEEEQRLLKSGSNDDSDMEIQEDEGSDSEVEDRQFRKQRTALDTLVPGRAGARIVGAMQGGDTEEDEESGDSEIDLDDDEDEEEDVEDDSMEISPSKSSHRAKKPEPLEESDNDF", "length": 413, "header": "tr|A0A8V0Z465-1|A0A8V0Z465_CHICK Isoform 1 of Clusterin associated protein 1 OS=Gallus gallus OX=9031 GN=CLUAP1 PE=3 SV=1 CANONICAL=A0A8V0Z465-1" }, "locus": { "chromosome": "14", "start_pos": 12830796, "end_pos": 12775090, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040277.1", "url": "https://www.ensembl.org/id/ENSGALT00010040277.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023357.1", "url": "https://www.ensembl.org/id/ENSGALP00010023357.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:426077", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:426077", "resource": "KEGG Pathway" }, { "id": "R-GGA-5620924", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620924", "resource": "Reactome", "description": "Intraflagellar transport" } ], "orthologs": [ { "uniprot_canonical_ac": "F6PWT1-1", "protein_name": "Clusterin associated protein 1", "gene_name": "CLUAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQNDIPSDVETEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSKRAEEDVSKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGKEVELRELRTEAVARPLEINETEKVMRIAIKDILAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKIEEELQKQYEIYLEKFRNLAYLEQQLEDHHRMEQERFEETENTLRLMQNKLKEEGKRLLKSGSNGDSDVDIQEDDESDSELEERRLSQLRTAMEVLTQGQPSKHVVGTMQGGDTDDDEDLEDSEIDMEDDEDDDDLEDESVALSAAKPSRRGRKPEPLEESDSDF", "length": 412 }, "evidence": [ { "id": "A0A8V0Z465", "url": "https://omabrowser.org/oma/group/A0A8V0Z465/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z465", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z465", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465" } ], "pmid": "" }, { "name": "microtubule organizing center", "id": "GO:0005815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z465", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z465", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z465", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z465", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z465" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4M0-1", "uniprot_ac": "A0A8V0Z4M0", "uniprot_id": "A0A8V0Z4M0_CHICK", "mass": { "chemical_mass": 139276.0, "monoisotopic_mass": 139276.0 }, "refseq": {}, "gene_names": [ { "name": "ZC3H8", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH-type containing 8", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZC3H8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0", "locus": { "chromosome": "3", "start_pos": 3442997, "end_pos": 3413619, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018002", "url": "https://www.ensembl.org/id/ENSGALG00010018002" } ] } } ], "crossref": [ { "id": "A0A8V0Z4M0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4M0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008269", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008269", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421230", "url": "https://www.ncbi.nlm.nih.gov/gene/421230", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421230", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421230", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RGMKQQQ", "url": "https://omabrowser.org/oma/group/RGMKQQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXT5", "url": "https://www.orthodb.org/?gene=A0A8V0YXT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z453", "url": "https://www.orthodb.org/?gene=A0A8V0Z453", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4M0", "url": "https://www.orthodb.org/?gene=A0A8V0Z4M0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4M7", "url": "https://www.orthodb.org/?gene=A0A8V0Z4M7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4N3", "url": "https://www.orthodb.org/?gene=A0A8V0Z4N3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1C259", "url": "https://www.orthodb.org/?gene=E1C259", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13119:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13119:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18345", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18345", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22623", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22623", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YXT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z453", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z453", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z453-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z453-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4M7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4N3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C259", "url": "https://www.uniprot.org/uniprotkb/E1C259", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1C259-1", "url": "https://www.uniprot.org/uniprotkb/E1C259-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHTTLPIHFSAACVESTEVCLSSSGGSCSFPMISDSLFALILFSLWKCRRTRIKYRGSRCIGFSSAFTNASVEFRKVTRGRREDGELEDGEIDDAAYEDVKEHGSKDDKQKNEKGHRKSRKKRKKEKEKKKSKRRRRDKHKHNSPSSDDSSDYSHDSDIERTERSHKKSSSSSYRDYDSSFSQHGHVSGNYMSSQKMQHKKNIKSKEYDDYSHYSDENFGNYNEEEKDEDFADQLKQYRQAKETSSSDLGPPFMKEPVKKQGMKGIQKGISQRGNNYGVGRGRGMQKKLKRKDRGRGRGGNKGSDGFHEDGKPVKKWVNMSQEFINQHTVEHKGKQICKYFLEGRCIKGEQCKFDHDAEIEKKKEICKFYIQGYCTKGENCIYLHNEFPCKFYHTGAKCYQGDKCKFSHAPLTAETKELLDKVLNNEEEPQNEDEKELEELRKRGIVPLPKPPPGVGLLPTPAEQYPFSESDIENYQDPSGDYKKIPSLFEIVVKPTVDLAHKIGKKPPTFYNSSSPPRPPFQGNDPHSQHMYNPGSSPGPGPGMPQGHNGPPMHPGSPGHHPCGGPQGMPQSPPMQGVPPGFLGPQNQSGMPMQGQQGGPPLTPPGLGGSYNAPGVQGHMVNMPRDNHCPPGPQYQQMPGERQPNMNYEPIQNPADFYDNYYSHQAVHNFQPANNSGDGSWHGEFTDHQAHLMAQESHQGGSESDCMSGHMGHKPAINVPDFLPAMQKALYVRLSQKHQRDGDSVSSQGQRAMSKEEDDNVNWYSSSEEEEGNSVKSILKTLKKQSENFRNQQQHSAEQHMLGIPTDPRLAKDKGAGPQAADPRLRASPRSNPRKPSESAALDPRLRDPRMHKVSDGGHASSSLVGAKLDLHHPHTGVKVKQKGMDDDEEDSERELRERAFLIPLEPLPGVTLRDPRSQLRQFSHIKMDVTLMKPNFAKHIVWAPEDLLPIPLPKPDPVSSINLPLPPLIADQRLNKLRNLKNDPHPNAMPADPRLAAKAKNNLVGRSGYLDQSADSHASSSSKLGDPRLQKNVDPRLHRLSNTDTYHGVTKESHPSKFDPRLARSAASSSQPSEAAAAKPDPDALPPYAPKLSASGVRLGTSGSLLSGISLYDPRDHSSSSDAAPASSGENGENQKKSILKNSAKNDPSLSEDVSLPKPASGVEKNPEGSTEATSDKANSNSKSQAKHSSAAPAVHNLPIQALSGLIRPQYSDPRQVRQPGQVTQTQDNDPNGESDDKSLKDVFKTFDPTASPFC", "length": 1257, "header": "tr|A0A8V0Z4M0-1|A0A8V0Z4M0_CHICK Isoform 1 of Zinc finger CCCH-type containing 8 OS=Gallus gallus OX=9031 GN=ZC3H8 PE=1 SV=1 CANONICAL=A0A8V0Z4M0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0/entry#A0A8V0YXT5-1", "sequence": { "sequence": "MKLTEDELKVGFDRDLHLGRVISFVEDGELEDGEIDDAAYEDVKEHGSKDDKQKNEKGHRKSRKKRKKEKEKKKSKRRRRDKHKHNSPSSDDSSDYSHDSDIERTERSHKKSSSSSYRDYDSSFSQHGHVSGNYMSSQKMQHKKNIKSKEYDDYSHYSDENFGNYNEEEKDEDFADQLKQYRQAKETSSSDLGPPFMKEPVKKQGMKGIQKGISQRGNNYGVGRGRGMQKKLKRKDRGRGRGGNKGSDGFHEDGKPVKKWVNMSQEFINQHTVEHKGKQICKYFLEGRCIKGEQCKFDHDAEIEKKKEICKFYIQGYCTKGENCIYLHNEFPCKFYHTGAKCYQGDKCKFSHAPLTAETKELLDKVLNNEEEPQNEDEKELEELRKRGIVPLPKPPPGVGLLPTPAEQYPFSESDIENYQDPSGDYKKIPSLFEIVVKPTVDLAHKIGKKPPTFYNSSSPPRPPFQGNDPHSQHMYNPGSSPGPGPGMPQGHNGPPMHPGSPGHHPCGGPQGMPQSPPMQGVPPGFLGPQNQSGMPMQGQQGGPPLTPPGLGGSYNAPGVQGHMVNMPRDNHCPPGPQYQQMPGERQPNMNYEPIQNPADFYDNYYSHQAVHNFQPANNSGDGSWHGEFTDHQAHLMAQESHQGGSESDCMSGHMGHKPAINVPDFLPAMQKALYVRLSQKHQRDGDSVSSQGQRAMSKEEDDNVNWYSSSEEEEGNSVKSILKTLKKQSENFRNQQQHSAEQHMLGIPTDPRLAKDKGAGPQAADPRLRASPRSNPRKPSESAALDPRLRDPRMHKVSDGGHASSSLVGAKLDLHHPHTGVKVKQKGMDDDEEDSERELRERAFLIPLEPLPGVTLRDPRSQLRQFSHIKMDVTLMKPNFAKHIVWAPEDLLPIPLPKPDPVSSINLPLPPLIADQRLNKLRNLKNDPHPNAMPADPRLAAKAKNNLVGRSGYLDQSADSHASSSSKLGDPRLQKNVDPRLHRLSNTDTYHGVTKESHPSKFDPRLARSAASSSQPSEAAAAKPDPDALPPYAPKLSASGVRLGTSGSLLSGISLYDPRDHSSSSDAAPASSGENGENQKKSILKNSAKNDPSLSEDVSLPKPASGVEKNPEGSTEATSDKANSNSKSQAKHSSAAPAVHNLPIQALSGLIRPQYSDPRQVRQPGQVTQTQDNDPNGESDDKSLKDVFKTFDPTASPFC", "length": 1200, "header": "tr|A0A8V0YXT5-1|A0A8V0Z4M0_CHICK Computationally mapped isoform of Zinc finger CCCH-type containing 8 OS=Gallus gallus OX=9031 GN=ZC3H8 PE=1 SV=1 CANONICAL=A0A8V0Z4M0-1" }, "locus": { "chromosome": "3", "start_pos": 3441642, "end_pos": 3419953, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043503.1", "url": "https://www.ensembl.org/id/ENSGALT00010043503.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025865.1", "url": "https://www.ensembl.org/id/ENSGALP00010025865.1" } ] } }, { "isoform_ac": "A0A8V0Z453-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0/entry#A0A8V0Z453-1", "sequence": { "sequence": "MHWREDGELEDGEIDDAAYEDVKEHGSKDDKQKNEKGHRKSRKKRKKEKEKKKSKRRRRDKHKHNSPSSDDSSDYSHDSDIERTERSHKKSSSSSYRDYDSSFSQHGHVSGNYMSSQKMQHKKNIKSKEYDDYSHYSDENFGNYNEEEKDEDFADQLKQYRQAKETSSSDLGPPFMKEPVKKQGMKGIQKGISQRGNNYGVGRGRGMQKKLKRKDRGRGRGGNKGSDGFHEDGKPVKKWVNMSQEFINQHTVEHKGKQICKYFLEGRCIKGEQCKFDHDAEIEKKKEICKFYIQGYCTKGENCIYLHNEFPCKFYHTGAKCYQGDKCKFSHAPLTAETKELLDKVLNNEEEPQNEDEKELEELRKRGIVPLPKPPPGVGLLPTPAEQYPFSESDIENYQDPSGDYKKIPSLFEIVVKPTVDLAHKIGKKPPTFYNSSSPPRPPFQGNDPHSQHMYNPGSSPGPGPGMPQGHNGPPMHPGSPGHHPCGGPQGMPQSPPMQGVPPGFLGPQNQSGMPMQGQQGGPPLTPPGLGGSYNAPGVQGHMVNMPRDNHCPPGPQYQQMPGERQPNMNYEPIQNPADFYDNYYSHQAVHNFQPANNSGDGSWHGEFTDHQAHLMAQESHQGGSESDCMSGHMGHKPAINVPDFLPAMQKALYVRLSQKHQRDGDSVSSQGQRAMSKEEDDNVNWYSSSEEEEGNSVKSILKTLKKQSENFRNQQQHSAEQHMLGIPTDPRLAKDKGAGPQAADPRLRASPRSNPRKPSESAALDPRLRDPRMHKVSDGGHASSSLVGAKLDLHHPHTGVKVKQKGMDDDEEDSERELRERAFLIPLEPLPGVTLRDPRSQLRQFSHIKMDVTLMKPNFAKHIVWAPEDLLPIPLPKPDPVSSINLPLPPLIADQRLNKLRNLKNDPHPNAMPADPRLAAKAKNNLVGRSGYLDQSADSHASSSSKLGDPRLQKNVDPRLHRLSNTDTYHGVTKESHPSKFDPRLARSAASSSQPSEAAAAKPDPDALPPYAPKLSASGVRLGTSGSLLSGISLYDPRDHSSSSDAAPASSGENGENQKKSILKNSAKNDPSLSEDVSLPKPASGVEKNPEGSTEATSDKANSNSKSQAKHSSAAPAVHNLPIQALSGLIRPQYSDPRQVRQPGQVTQTQDNDPNGESDDKSLKDVFKTFDPTASPFC", "length": 1179, "header": "tr|A0A8V0Z453-1|A0A8V0Z453_CHICK Computationally mapped isoform of Zinc finger CCCH-type containing 8 OS=Gallus gallus OX=9031 GN=ZC3H8 PE=1 SV=1 CANONICAL=A0A8V0Z4M0-1" }, "locus": { "chromosome": "3", "start_pos": 3441642, "end_pos": 3414293, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043519.1", "url": "https://www.ensembl.org/id/ENSGALT00010043519.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025877.1", "url": "https://www.ensembl.org/id/ENSGALP00010025877.1" } ] } }, { "isoform_ac": "A0A8V0Z4M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0/entry#A0A8V0Z4M0-1", "sequence": { "sequence": "MHTTLPIHFSAACVESTEVCLSSSGGSCSFPMISDSLFALILFSLWKCRRTRIKYRGSRCIGFSSAFTNASVEFRKVTRGRREDGELEDGEIDDAAYEDVKEHGSKDDKQKNEKGHRKSRKKRKKEKEKKKSKRRRRDKHKHNSPSSDDSSDYSHDSDIERTERSHKKSSSSSYRDYDSSFSQHGHVSGNYMSSQKMQHKKNIKSKEYDDYSHYSDENFGNYNEEEKDEDFADQLKQYRQAKETSSSDLGPPFMKEPVKKQGMKGIQKGISQRGNNYGVGRGRGMQKKLKRKDRGRGRGGNKGSDGFHEDGKPVKKWVNMSQEFINQHTVEHKGKQICKYFLEGRCIKGEQCKFDHDAEIEKKKEICKFYIQGYCTKGENCIYLHNEFPCKFYHTGAKCYQGDKCKFSHAPLTAETKELLDKVLNNEEEPQNEDEKELEELRKRGIVPLPKPPPGVGLLPTPAEQYPFSESDIENYQDPSGDYKKIPSLFEIVVKPTVDLAHKIGKKPPTFYNSSSPPRPPFQGNDPHSQHMYNPGSSPGPGPGMPQGHNGPPMHPGSPGHHPCGGPQGMPQSPPMQGVPPGFLGPQNQSGMPMQGQQGGPPLTPPGLGGSYNAPGVQGHMVNMPRDNHCPPGPQYQQMPGERQPNMNYEPIQNPADFYDNYYSHQAVHNFQPANNSGDGSWHGEFTDHQAHLMAQESHQGGSESDCMSGHMGHKPAINVPDFLPAMQKALYVRLSQKHQRDGDSVSSQGQRAMSKEEDDNVNWYSSSEEEEGNSVKSILKTLKKQSENFRNQQQHSAEQHMLGIPTDPRLAKDKGAGPQAADPRLRASPRSNPRKPSESAALDPRLRDPRMHKVSDGGHASSSLVGAKLDLHHPHTGVKVKQKGMDDDEEDSERELRERAFLIPLEPLPGVTLRDPRSQLRQFSHIKMDVTLMKPNFAKHIVWAPEDLLPIPLPKPDPVSSINLPLPPLIADQRLNKLRNLKNDPHPNAMPADPRLAAKAKNNLVGRSGYLDQSADSHASSSSKLGDPRLQKNVDPRLHRLSNTDTYHGVTKESHPSKFDPRLARSAASSSQPSEAAAAKPDPDALPPYAPKLSASGVRLGTSGSLLSGISLYDPRDHSSSSDAAPASSGENGENQKKSILKNSAKNDPSLSEDVSLPKPASGVEKNPEGSTEATSDKANSNSKSQAKHSSAAPAVHNLPIQALSGLIRPQYSDPRQVRQPGQVTQTQDNDPNGESDDKSLKDVFKTFDPTASPFC", "length": 1257, "header": "tr|A0A8V0Z4M0-1|A0A8V0Z4M0_CHICK Isoform 1 of Zinc finger CCCH-type containing 8 OS=Gallus gallus OX=9031 GN=ZC3H8 PE=1 SV=1 CANONICAL=A0A8V0Z4M0-1" }, "locus": { "chromosome": "3", "start_pos": 3441642, "end_pos": 3421127, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043502.1", "url": "https://www.ensembl.org/id/ENSGALT00010043502.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025864.1", "url": "https://www.ensembl.org/id/ENSGALP00010025864.1" } ] } }, { "isoform_ac": "A0A8V0Z4M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0/entry#A0A8V0Z4M7-1", "sequence": { "sequence": "MLILEDGELEDGEIDDAAYEDVKEHGSKDDKQKNEKGHRKSRKKRKKEKEKKKSKRRRRDKHKHNSPSSDDSSDYSHDSDIERTERSHKKSSSSSYRDYDSSFSQHGHVSGNYMSSQKMQHKKNIKSKEYDDYSHYSDENFGNYNEEEKDEDFADQLKQYRQAKETSSSDLGPPFMKEPVKKQGMKGIQKGISQRGNNYGVGRGRGMQKKLKRKDRGRGRGGNKGSDGFHEDGKPVKKWVNMSQEFINQHTVEHKGKQICKYFLEGRCIKGEQCKFDHDAEIEKKKEICKFYIQGYCTKGENCIYLHNEFPCKFYHTGAKCYQGDKCKFSHAPLTAETKELLDKVLNNEEEPQNEDEKELEELRKRGIVPLPKPPPGVGLLPTPAEQYPFSESDIENYQDPSGDYKKIPSLFEIVVKPTVDLAHKIGKKPPTFYNSSSPPRPPFQGNDPHSQHMYNPGSSPGPGPGMPQGHNGPPMHPGSPGHHPCGGPQGMPQSPPMQGVPPGFLGPQNQSGMPMQGQQGGPPLTPPGLGGSYNAPGVQGHMVNMPRDNHCPPGPQYQQMPGERQPNMNYEPIQNPADFYDNYYSHQAVHNFQPANNSGDGSWHGEFTDHQAHLMAQESHQGGSESDCMSGHMGHKPAINVPDFLPAMQKALYVRLSQKHQRDGDSVSSQGQRAMSKEEDDNVNWYSSSEEEEGNSVKSILKTLKKQSENFRNQQQHSAEQHMLGIPTDPRLAKDKGAGPQAADPRLRASPRSNPRKPSESAALDPRLRDPRMHKVSDGGHASSSLVGAKLDLHHPHTGVKVKQKGMDDDEEDSERELRERAFLIPLEPLPGVTLRDPRSQLRQFSHIKMDVTLMKPNFAKHIVWAPEDLLPIPLPKPDPVSSINLPLPPLIADQRLNKLRNLKNDPHPNAMPADPRLAAKAKNNLVGRSGYLDQSADSHASSSSKLGDPRLQKNVDPRLHRLSNTDTYHGVTKESHPSKFDPRLARSAASSSQPSEAAAAKPDPDALPPYAPKLSASGVRLGTSGSLLSGISLYDPRDHSSSSDAAPASSGENGENQKKSILKNSAKNDPSLSEDVSLPKPASGVEKNPEGSTEATSDKANSNSKSQAKHSSAAPAVHNLPIQALSGLIRPQYSDPRQVRQPGQVTQTQDNDPNGESDDKSLKDVFKTFDPTASPFC", "length": 1179, "header": "tr|A0A8V0Z4M7-1|A0A8V0Z4M7_CHICK Computationally mapped isoform of Zinc finger CCCH-type containing 8 OS=Gallus gallus OX=9031 GN=ZC3H8 PE=1 SV=1 CANONICAL=A0A8V0Z4M0-1" }, "locus": { "chromosome": "3", "start_pos": 3441642, "end_pos": 3415988, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043510.1", "url": "https://www.ensembl.org/id/ENSGALT00010043510.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025869.1", "url": "https://www.ensembl.org/id/ENSGALP00010025869.1" } ] } }, { "isoform_ac": "A0A8V0Z4N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0/entry#A0A8V0Z4N3-1", "sequence": { "sequence": "MSPLFFFSLALVLLVREDGELEDGEIDDAAYEDVKEHGSKDDKQKNEKGHRKSRKKRKKEKEKKKSKRRRRDKHKHNSPSSDDSSDYSHDSDIERTERSHKKSSSSSYRDYDSSFSQHGHVSGNYMSSQKMQHKKNIKSKEYDDYSHYSDENFGNYNEEEKDEDFADQLKQYRQAKETSSSDLGPPFMKEPVKKQGMKGIQKGISQRGNNYGVGRGRGMQKKLKRKDRGRGRGGNKGSDGFHEDGKPVKKWVNMSQEFINQHTVEHKGKQICKYFLEGRCIKGEQCKFDHDAEIEKKKEICKFYIQGYCTKGENCIYLHNEFPCKFYHTGAKCYQGDKCKFSHAPLTAETKELLDKVLNNEEEPQNEDEKELEELRKRGIVPLPKPPPGVGLLPTPAEQYPFSESDIENYQDPSGDYKKIPSLFEIVVKPTVDLAHKIGKKPPTFYNSSSPPRPPFQGNDPHSQHMYNPGSSPGPGPGMPQGHNGPPMHPGSPGHHPCGGPQGMPQSPPMQGVPPGFLGPQNQSGMPMQGQQGGPPLTPPGLGGSYNAPGVQGHMVNMPRDNHCPPGPQYQQMPGERQPNMNYEPIQNPADFYDNYYSHQAVHNFQPANNSGDGSWHGEFTDHQAHLMAQESHQGGSESDCMSGHMGHKPAINVPDFLPAMQKALYVRLSQKHQRDGDSVSSQGQRAMSKEEDDNVNWYSSSEEEEGNSVKSILKTLKKQSENFRNQQQHSAEQHMLGIPTDPRLAKDKGAGPQAADPRLRASPRSNPRKPSESAALDPRLRDPRMHKVSDGGHASSSLVGAKLDLHHPHTGVKVKQKGMDDDEEDSERELRERAFLIPLEPLPGVTLRDPRSQLRQFSHIKMDVTLMKPNFAKHIVWAPEDLLPIPLPKPDPVSSINLPLPPLIADQRLNKLRNLKNDPHPNAMPADPRLAAKAKNNLVGRSGYLDQSADSHASSSSKLGDPRLQKNVDPRLHRLSNTDTYHGVTKESHPSKFDPRLARSAASSSQPSEAAAAKPDPDALPPYAPKLSASGVRLGTSGSLLSGISLYDPRDHSSSSDAAPASSGENGENQKKSILKNSAKNDPSLSEDVSLPKPASGVEKNPEGSTEATSDKANSNSKSQAKHSSAAPAVHNLPIQALSGLIRPQYSDPRQVRQPGQVTQTQDNDPNGESDDKSLKDVFKTFDPTASPFC", "length": 1191, "header": "tr|A0A8V0Z4N3-1|A0A8V0Z4M0_CHICK Computationally mapped isoform of Zinc finger CCCH-type containing 8 OS=Gallus gallus OX=9031 GN=ZC3H8 PE=1 SV=1 CANONICAL=A0A8V0Z4M0-1" }, "locus": { "chromosome": "3", "start_pos": 3441642, "end_pos": 3414426, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043516.1", "url": "https://www.ensembl.org/id/ENSGALT00010043516.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025874.1", "url": "https://www.ensembl.org/id/ENSGALP00010025874.1" } ] } }, { "isoform_ac": "E1C259-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0/entry#E1C259-1", "sequence": { "sequence": "MAFESLFSKPPNPVLDPNMPDSDRQHAGDEREDGELEDGEIDDAAYEDVKEHGSKDDKQKNEKGHRKSRKKRKKEKEKKKSKRRRRDKHKHNSPSSDDSSDYSHDSDIERTERSHKKSSSSSYRDYDSSFSQHGHVSGNYMSSQKMQHKKNIKSKEYDDYSHYSDENFGNYNEEEKDEDFADQLKQYRQAKETSSSDLGPPFMKEPVKKQGMKGIQKGISQRGNNYGVGRGRGMQKKLKRKDRGRGRGGNKGSDGFHEDGKPVKKWVNMSQEFINQHTVEHKGKQICKYFLEGRCIKGEQCKFDHDAEIEKKKEICKFYIQGYCTKGENCIYLHNEFPCKFYHTGAKCYQGDKCKFSHAPLTAETKELLDKVLNNEEEPQNEDEKELEELRKRGIVPLPKPPPGVGLLPTPAEQYPFSESDIENYQDPSGDYKKIPSLFEIVVKPTVDLAHKIGKKPPTFYNSSSPPRPPFQGNDPHSQHMYNPGSSPGPGPGMPQGHNGPPMHPGSPGHHPCGGPQGMPQSPPMQGVPPGFLGPQNQSGMPMQGQQGGPPLTPPGLGGSYNAPGVQGHMVNMPRDNHCPPGPQYQQMPGERQPNMNYEPIQNPADFYDNYYSHQAVHNFQPANNSGDGSWHGEFTDHQAHLMAQESHQGGSESDCMSGHMGHKPAINVPDFLPAMQKALYVRLSQKHQRDGDSVSSQGQRAMSKEEDDNVNWYSSSEEEEGNSVKSILKTLKKQSENFRNQQQHSAEQHMLGIPTDPRLAKDKGAGPQAADPRLRASPRSNPRKPSESAALDPRLRDPRMHKVSDGGHASSSLVGAKLDLHHPHTGVKVKQKGMDDDEEDSERELRERAFLIPLEPLPGVTLRDPRSQLRQFSHIKMDVTLMKPNFAKHIVWAPEDLLPIPLPKPDPVSSINLPLPPLIADQRLNKLRNLKNDPHPNAMPADPRLAAKAKNNLVGRSGYLDQSADSHASSSSKLGDPRLQKNVDPRLHRLSNTDTYHGVTKESHPSKFDPRLARSAASSSQPSEAAAAKPDPDALPPYAPKLSASGVRLGTSGSLLSGISLYDPRDHSSSSDAAPASSGENGENQKKSILKNSAKNDPSLSEDVSLPKPASGVEKNPEGSTEATSDKANSNSKSQAKHSSAAPAVHNLPIQALSGLIRPQYSDPRQVRQPGQVTQTQDNDPNGESDDKSLKDVFKTFDPTASPFC", "length": 1206, "header": "tr|E1C259-1|A0A8V0Z4M0_CHICK Computationally mapped isoform of Zinc finger CCCH-type containing 8 OS=Gallus gallus OX=9031 GN=ZC3H8 PE=1 SV=2 CANONICAL=A0A8V0Z4M0-1" }, "locus": { "chromosome": "3", "start_pos": 3441642, "end_pos": 3414006, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043529.1", "url": "https://www.ensembl.org/id/ENSGALT00010043529.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025886.1", "url": "https://www.ensembl.org/id/ENSGALP00010025886.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 461, "start_aa": "Thr", "end_pos": 461, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr461", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421230", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421230", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AXB3-1", "protein_name": "Zinc finger CCCH-type containing 6", "gene_name": "ZC3H6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTDSEHAGHDREDGELEDGEIDDAGFEETQEQEVKEDEKQKNEKVYRKSRKKHKKEKEKKKSKRRKREKHKYNSPSSDDSSDYSVDSEVEHTESSHKKRTGFYRDYDIPFPQHGHISGSYMTSKKSQHNRKFKSKEYDEYSTYSDDNFGNYSDDNFGNYSQETEEDFASQLKQYRQAKETSNTALGSSFSKEPGKKQRLKGIQQGIEHRVKSFNVARGRGLPKKIKRKDRGGRTNKGPNVFSGTDDFQEYSKPGKKWKVMTQEFINQHTVEHKGKQICKYFLEGRCIKGDQCKFDHDAELEKRKEICKFYLQGYCTKGENCIYMHNEFPCKFYHSGAKCYQGDNCKFSHDDLTKETKKLLDKVLNTEEEHANEDERELEELRKRGITPLPKPPPGVGLLPTPPEHFPFSDPEDDFQADLSDDFKKIPSLFEIVVKPTVDLAQKIGKKPPAFYNSASPPGPQFQEGSPHPQHIYSSGSSPVHGPNMSQGHSSPVMHPGSPGHHPCAGPPGLPVPQSPPLPPGQPGIVGPHNQAGVLAQPDTHLVPPSMSGTYHCLGFPEHMMKVPREDPCSPGSSHLQSPGERQLNTSYESLQNPAEFYDNYYAQHAVHNFQSPSHSGDGTWHSEFAQHQPPIVQDSPHRGSASDCISSVTGHAPLPAPGLLPAVQRALFVRLTQKYPEDEEPGSTQPPRAPSKEEDDTVNWYSSSEEEEGSSVKSILKTLQKQTETLRNQQPSTELSPPTDPRLAKEKMKGNQVVDPRLRTISRQDIRKSSESAPLDLRLVWDPRKLRGNGSGQVGSSTGGAKFDLHHGNTGPNVKDKRGDDDDEDTERELREKAFLIPLDSSPGIMLQDPRSQLRQFSHIKMDIVLTKPNFAKHIVWAPEDLLPVPLPKPDPVSSINLPLPPLIADQRLSRLWNTKSDHQNTVTIDSKLAAKAKINPTNREGYLEQFGDLHSSGSKLGDPRLQKNFDPRLHRLHNTESHQAVMKDSHSSKGAPHLARSNTGSSQPLGAVPSNSGPGALPPYAPKLSSSAGLPPGTPSSVLSGISLYDSRECGSSSTSELASENTENQKKSGGLESSDKNDPSPEEATLPQKIAPNVDVTVDGPADPQADVPRSSDMVQVPAVHSLPIQALTGLIRPQYSDPRQSRQPGQVSPTPENDPSRETDDKSLKEVFKTFDPTASPFC", "length": 1183 }, "evidence": [ { "id": "A0A8V0Z4M0", "url": "https://omabrowser.org/oma/group/A0A8V0Z4M0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1LTU5-1", "protein_name": "Zinc finger CCCH type containing 6", "gene_name": "Zc3h6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTDSEHAGHDREDGELEDGEIDDAGFEETQDHEAKENEKQKNEKAYRKSRKKHKKEREKKKSKRRKHEKHKHNSPSGDSSDYSLDSDVEHMQSSHKKRTSFYRDYDVPFSQHRRISGSYRTSKKSQHNKKFNSKEYAESSFYSDDYFGNYSDDNFGNYSNQEGEEDFSSQLKYYRQSQERSGSSFSKESGKKLRSRESPPGTEYRIKNFNVSHGHLLPRKIRRKEHCGARVIKGPHVFSAVDDFQEYSKPGKKWKVMTQEFINQHTVEHKGKQICKYFLEGRCIKGDHCKFNHDAELEKKKEVLNADEELVNEDERELEELRKHGITPLPKPPPGVGLLPTPSEHFPFSDPEDDFETDLSDDTKKIPSLFEIVVKPTVDLAHKIGKKPPAFYNSTSPPGPQYEESSHCPQHMYSSESSPGPGSNIPQGSESPVRHPGSPGHHPCIGPPGPPMQENPPLLPGSSEVVGPHSQAGGLVQLDTLPSMGGAYHSPGFPGHVMKVPRESHSSTASLYQQMPSEVQLSADSECLQGSAEVYDDYYPQNAAHSFQPPDNSADEMWHEEFAQQQPPGAHDSPHLGSGPDTSSTLTSHCPLPASGLPPAVQRALFIPLTQRYQEDEEPAGTQPHRASSKEEDDTVNWYSSSEEEEGSGVKSILRTLQKQTGTLRNQQHPPTELSIPTDPRLAKEKRKGNQVVDPRLRTVPRQDIRKPHESVPVDLRLVWDPRKFRGNGGAPGGSSATGAKFDLRHTSAGANHKPKRRDDDDEDTERELREKAFLIPLDSSPGVVLQDPRSQLRQFSHIKMDIILNKPNFAKHIVWAPEDLLPVPLPKPDPVSSINLPLPPLIADQRLSRLWNTKSDHQGTLSLDPTSAAKARMSLTPREGCLEQSGDLHSSGGKLGDPRLQKNFDPRLHRLPNTESPQVAIKDSHSLRNALPLARWNPALSQPSTAAPVTVAPVTLPLYASKLSSDGLPPGTPSSVLSGISLYDPRDKGSLSATELSTISSGENTENQKKSGVKNSDKNQPSPGEVILPQKTTADMKVPVDGPADVQTDVLSSADGVQAPAVHSLPIQALTGLIGPPYSDPRQAREPGQASPTPDDDPSRETDDKSLKEVFKTFDPTASPFC", "length": 1123 }, "evidence": [ { "id": "A0A8V0Z4M0", "url": "https://omabrowser.org/oma/group/A0A8V0Z4M0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P61129-1", "protein_name": "Zinc finger CCCH domain-containing protein 6", "gene_name": "ZC3H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDSEHAGHDREDGELEDGEIDDAGFEEIQEKEAKENEKQKSEKAYRKSRKKHKKEREKKKSKRRKREKHKHNSPSSDDSSDYSLDSDVEHTESSHKKRTGFYRDYDIPFTQRGHISGSYITSKKGQHNKKFKSKEYDEYSTYSDDNFGNYSDDNFGNYGQETEEDFANQLKQYRQAKETSNIALGSSFSKESGKKQRMKGVQQGIEQRVKSFNVGRGRGLPKKIKRKERGGRTNKGPNVFSVSDDFQEYNKPGKKWKVMTQEFINQHTVEHKGKQICKYFLEGRCIKGDQCKFDHDAELEKRKEICKFYLQGYCTKGENCIYMHNEFPCKFYHSGAKCYQGDNCKFSHDDLTKETKKLLDKVLNTDEELINEDERELEELRKRGITPLPKPPPGVGLLPTPPEHFPFSDPEDDFQTDFSDDFRKIPSLFEIVVKPTVDLAHKIGRKPPAFYTSASPPGPQFQGSSPHPQHIYSSGSSPGPGPNMSQGHSSPVMHPGSPGHHPCAGPPGLPVPQSPPLPPGPPEIVGPQNQAGVLVQPDTSLTPPSMGGAYHSPGFPGHVMKVPRENHCSPGSSYQQSPGEMQLNTNYESLQNPAEFYDNYYAQHSIHNFQPPNNSGDGMWHGEFAQQQPPVVQDSPNHGSGSDGSSTRTGHGPLPVPGLLPAVQRALFVRLTQRYQEDEEQTSTQPHRAPSKEEDDTVNWYSSSEEEEGSSVKSILKTLQKQTETLRNQQQPSTELSTPTDPRLAKEKSKGNQVVDPRLRTIPRQDIRKPSESAPLDLRLAWDPRKLRGNGSGHIGSSVGGAKFDLHHANAGTNVKHKRGDDDDEDTERELREKAFLIPLDASPGIMLQDPRSQLRQFSHIKMDITLTKPNFAKHIVWAPEDLLPVPLPKPDPVSSINLPLPPLIADQRLNRLWNTKSDLHQNTVSIDPKLAAKAKINTTNREGYLEQFGDSHGSGAKLGDPRLQKNFDPRLHRLPNTESHQVVMKDSHASKGAPHLPRSNPGSSQPSGAGTSNSGSGALPPYAPKLSSSAGLPLGTSTSVLSGISLYDPRDHGSSSTSELATASSGENSKNQKKSGGLKSSDKTEPSPGEAILPQKPSPNVGVTLEGPADPQADVPRSSGKVQVPAVHSLPVQALTGLIRPQYSDPRQARQPGQGSPTPDNDPGRETDDKSLKEVFKTFDPTASPFC", "length": 1189 }, "evidence": [ { "id": "A0A8V0Z4M0", "url": "https://omabrowser.org/oma/group/A0A8V0Z4M0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BYK8-1", "protein_name": "Zinc finger CCCH domain-containing protein 6", "gene_name": "Zc3h6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDSEHAGHDREDGELEDGEIDDAGFEETQDQEAKENEKQKNEKAYRKSRKKHKKEREKKKSKRRKHEKHKHNSPSGDDSSDYSLDSDVERMQSSRKKRTSSYRDYDVPFSQHRRISGSYMTSKKSQHNKKTNSKEYAESSFYSDDYFGNYSDDNFGNYSNQEGEEDFSSQLKYYRQSQESSGSSFSKESGKKLRSKGSPPGTEYRIKSFDVSHGHLLPKKIRRKEHCGARVIKGPYVFSGMDDFQEYSKPGKKWKVMTQEFINQHTVEHKGKQICKYFLEGRCIKGDHCKFNHDAELEKKKEVCKYYLQGYCTKGENCIYMHSEFPCKFYHSGAKCYQGDKCKFSHDDLTKETRKLLDKVLNADEELVNEDERELEELRKRGITPLPKPPPGVGLLPTPSEHFPFSDPEDDFETDLSDDMKKIPSLFEIVVKPTVDLAHKIGKKPPAFYNSTSPPGPQFEESSHCPQRMYSSESSPGPGSKVPQGCESPVRHPGSPGHHPCVGPPGPPMQENPSLLPSSSEIVGPHSQAGGLVQLDTLPSMGGAYHSPGFPGHSVKVPRESHSSPASLYQQMPSEMQRSADSESMQGSAEFYDDYYPQHAAHNFQPPDNSADEMWHEEFAQQQPPIARDTAHLGSGPNSSSRMTSHCPLSASGLPPAVQRALFIPLTQRYQEDEEPAGTQPHRASSKEEDDTANWYSSSEEEEGSGVKSILRTLQKQTGTLRNQQLPPTELSVPTDPRLAKEKRKRNQVVDPRLRTVPRQDIKKPHESVPVDLRLVWDPKKLRGNGGAPGGSSARGAEFDLRHTNAGANHKSKRREDDDEDSERELREKAFLIPLDSSPGIVLQDPRSQLRQFSHIKMDIILNKPNFAKHIVWAPEDLLPVPLPKPDPVSSINLPLPPLIADQRLNRLWNTKSDHQGALSLDPTSAAKAKLSLTHREGCLEQSGDLHSSGGKLGDPRLQKNFDPRLHRLPNTESHQVTAKDSHSSRSALPLARWNPALSQPSTAAPINVASVTPPLYAPKLSSEGLPPGTSSSVLSGISLYDPRDKGSLSATELSTISSGENTESQKKSGLKNSDKNQPSPGEVTVPQNTTADMEVPVDGPVDMQTDILRSADKVQVPAVHSLPIQALTGLLRPPYSDPRQAREPGQASPTPDEETDDKPLKEVFKTFDPTASPFC", "length": 1177 }, "evidence": [ { "id": "A0A8V0Z4M0", "url": "https://omabrowser.org/oma/group/A0A8V0Z4M0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription, elongation", "id": "GO:0032785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032785", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 675, "end_pos": 677, "annotation": "n_glycosylation_sequon" }, { "start_pos": 69, "end_pos": 71, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4M0" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 333, "end_pos": 359, "start_aa": "Lys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 461 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 319, "end_pos": 321 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 588, "end_pos": 590 }, { "start_pos": 675, "end_pos": 677 }, { "start_pos": 69, "end_pos": 71 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4H3-1", "uniprot_ac": "A0A8V0Z4H3", "uniprot_id": "A0A8V0Z4H3_CHICK", "mass": { "chemical_mass": 219187.0, "monoisotopic_mass": 219187.0 }, "refseq": {}, "gene_names": [ { "name": "EML6", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3" } ] } ], "protein_names": [ { "name": "EMAP like 6", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "EML6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3", "locus": { "chromosome": "3", "start_pos": 2739286, "end_pos": 2858501, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016762", "url": "https://www.ensembl.org/id/ENSGALG00010016762" } ] } } ], "crossref": [ { "id": "ENSGALG00000008139", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008139", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXU0", "url": "https://www.orthodb.org/?gene=A0A8V0YXU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4H3", "url": "https://www.orthodb.org/?gene=A0A8V0Z4H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BZK6", "url": "https://www.orthodb.org/?gene=E1BZK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03451", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03451", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YXU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZK6", "url": "https://www.uniprot.org/uniprotkb/E1BZK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BZK6-1", "url": "https://www.uniprot.org/uniprotkb/E1BZK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADRTAPRCRLRLEWVYGYRGHQCRNNLYYTAGKEVVYFVAGVGVVYNTREHSQKFFLGHNDDIISLAVHPDKTLVATGQVGKDPYICVWDSYRVQTVSVLKDAHTHGVACLAFDSDGQRLASVGLDAKNTVCIWDWKRGKLLAAATGHSDRIFDISWDQYQPNRIVSCGVKHIKFWTLCGNALTAKRGIFGKTGDLQTILCLACAKEDITYSGALNGDIYVWKGLNLVRTIQGAHSAGIFSMYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQDSEIFEVLVRERDKPMLIMQGHCEGELWALAVHPKKPLAVTGSDDRSVRLWSLADHALIARCNMEEAVRSVSFSPDGSQLALGMKDGSFIVLRVRDMTEVVHIKDRKEVIHEMKFSPDGSYLAVGSNDGPVDIYAVAQRYKKIGECNKSSSFITHIDWSVDSKFLQTNDGAGERLFYKMPSGKHLTNKDEIKGIHWASWTCVIGSEVNGIWPKYTNVTDVNSVDGNYNSSVLVTGDDFGLVKLFRFPCLRKGAKFRKYVGHSAHVTNVRWSHDFQWVLSTGGADHSVFQWQFIPEGITNGILETAPQEGGIDSYSEESDSDLSDVPELDSDIEQEAQINYDRQVYKEDLPQLKQQSKEKNHSVPFLKRERAPEDSLKLQFIHGYRGYDCRNNLFYTQTGEVVYHIAAVAVVYNRQQHSQRLYLGHDDDILSLSIHPVKDYVATGQVGRDAAIHVWDTQTLKCLSLLKGQHQRGVCALDFSADGKCLASVGLDDNHAIVFWDWKKGEKLATTRGHKDKIFVVKCNPHHVDKLVTVGMKHIKFWQQTGGGFTSRRGTFGSSGKLETMMSVSYGRIEDLVFSGAATGDIFIWKDTLLLKTVKAHDGPVFAMHALDKGFVTGGKDGIVALWDDMFERCLKTYAIKRAALSSSSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPVCATVSDDKTLRIWELSSQHRMLAVRKLKKGGRCCAFSPDGKALAVGLNDGSFLVVNADTVEDMVSFHHRKEMISDIKFSRETGKYLAVASHDNFVDIYNVLTSKRVGICKGASSYITHIDWDSRGKLLQVNSGAKEQLFFEAPRGKRHVIRIAELEKIEWDTWTCVLGPSCEGIWPMHSDVTVVNAATLTKDGTLLATGDDFGFVKLFSYPVKGQHAKFKKYVGHSAQVTNVRWLHNDSVLLTVGGADTALMIWTREFLGIQESKLVDSEESDTDAEEDGGYDSDVAREKAIDYTTKIYAVSIREMEGTKPHQQLKEVSVEERGSRPPVSRAAPQPEKLQKNNINKKRKLVEELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAAAGIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYKNIVATSQIGDMTEFSGTTPTIHVWDAMSKQTISMLRCFHTKGVNYVNFSATGKLLVSVGVDPEHTITVWRWQEGAKVASRGGHLERIFVVEFRPDSDTQFVSVGVKHMKFWTLAGSALLCKKGVIGSMEDAKMQTMLSVAFGANNLTFTGAINGDVYVWKDHFLVRLVAKAHTGPVFTMYTTLRDGLIVTGGKERPTKEGGAVKLWDQEMKRCRAFQLETGQLIECVRSVCRGKGKILVGTKDGEILEVGEKNAASNLLIDCHMEGEIWGLATHPSKDLFISASNDGTARIWDLCDKKLLNKVNLGHPARCAAYSPDGEMVAIGMKNGEFVILLVNSLKVWGKKRDRKSAIQDIRISPDNRFLAVGSQEHTVDFYDLTQGTTLNRIGYCKDIASFVIQMDFSADSRYIQVSTGAYKRQVHEVPLGKQITDTATIEKITWATWTSILGDEVIGIWPRNADKADVNCACVTHAGLNIVTGDDFGLVKLFDFPCTEKFAKHKRYFGHSAHVTNIRFSHDDNYVISTGGDDCSVFVWRCL", "length": 1968, "header": "tr|A0A8V0Z4H3-1|A0A8V0Z4H3_CHICK Isoform 1 of EMAP like 6 OS=Gallus gallus OX=9031 GN=EML6 PE=3 SV=1 CANONICAL=A0A8V0Z4H3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3/entry#A0A8V0YXU0-1", "sequence": { "sequence": "MADRTAPRCRLRLEWVYGYRGHQCRNNLYYTAGKEVVYFVAGVGVVYNTREHSQKFFLGHNDDIISLAVHPDKTLVATGQVGKDPYICVWDSYRVQTVSVLKDAHTHGVACLAFDSDGQRLASVGLDAKNTVCIWDWKRGKLLAAATGHSDRIFDISWDQYQPNRIVSCGVKHIKFWTLCGNALTAKRGIFGKTGDLQTILCLACAKEDITYSGALNGDIYVWKGLNLVRTIQGAHSAGIFSMYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQDSEIFEVLVRERDKPMLIMQGHCEGELWALAVHPKKPLAVTGSDDRSVRLWSLADHALIARCNMEEAVRSVSFSPDGSQLALGMKDGSFIVLRVRDMTEVVHIKDRKEVIHEMKFSPDGSYLAVGSNDGPVDIYAVAQRYKKIGECNKSSSFITHIDWSVDSKFLQTNDGAGERLFYKMPSGKHLTNKDEIKGIHWASWTCVIGSEVNGIWPKYTNVTDVNSVDGNYNSSVLVTGDDFGLVKLFRFPCLRKGAKFRKYVGHSAHVTNVRWSHDFQWVLSTGGADHSVFQWQFIPEGITNGILETAPQEGGIDSYSEESDSDLSDVPELDSDIEQEAQINYDRQVYKEDLPQLKQQSKEKNHSVPFLKRERAPEDSLKLQFIHGYRGYDCRNNLFYTQTGEVVYHIAAVAVVYNRQQHSQRLYLGHDDDILSLSIHPVKDYVATGQVGRDAAIHVWDTQTLKCLSLLKGQHQRGVCALDFSADGKCLASVGLDDNHAIVFWDWKKGEKLATTRGHKDKIFVVKCNPHHVDKLVTVGMKHIKFWQQTGGGFTSRRGTFGSSGKLETMMSVSYGRIEDLVFSGAATGDIFIWKDTLLLKTVKAHDGPVFAMHALDKGFVTGGKDGIVALWDDMFERCLKTYAIKRAALSSSSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPVCATVSDDKTLRIWELSSQHRMLAVRKLKKGGRCCAFSPDGKALAVGLNDGSFLVVNADTVEDMVSFHHRKEMISDIKFSRETGKYLAVASHDNFVDIYNVLTSKRVGICKGASSYITHIDWDSRGKLLQVNSGAKEQLFFEAPRGKRHVIRIAELEKIEWDTWTCVLGPSCEGIWPMHSDVTVVNAATLTKDGTLLATGDDFGFVKLFSYPVKGQHAKFKKYVGHSAQVTNVRWLHNDSVLLTVGGADTALMIWTREFLGIQESKLVDSEESDTDAEEDGGYDSDVAREKAIDYTTKIYAVSIREMEGTKPHQQLKEVSVEERQGIVKGSRPPVSRAAPQPEKLQKNNINKKRKLVEELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAAAGIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYKNIVATSQIGTTPTIHVWDAMSKQTISMLRCFHTKGVNYVNFSATGKLLVSVGVDPEHTITVWRWQEGAKVASRGGHLERIFVVEFRPDSDTQFVSVGVKHMKFWTLAGSALLCKKGVIGSMEDAKMQTMLSVAFGANNLTFTGAINGDVYVWKDHFLVRLVAKAHTGPVFTMYTTLRDGLIVTGGKERPTKEGGAVKLWDQEMKRCRAFQLETGQLIECVRSVCRGKGKILVGTKDGEILEVGEKNAASNLLIDCHMEGEIWGLATHPSKDLFISASNDGTARIWDLCDKKLLNKVNLGHPARCAAYSPDGEMVAIGMKNGEFVILLVNSLKVWGKKRDRKSAIQDIRISPDNRFLAVGSQEHTVDFYDLTQGTTLNRIGYCKDIASFVIQMDFSADSRYIQVSTGAYKRQVHEVPLGKQITDTATIEKITWATWTSILGDEVIGIWPRNADKADVNCACVTHAGLNIVTGDDFGLVKLFDFPCTEKFAKHKRYFGHSAHVTNIRFSHDDNYVISTGGDDCSVFVWRCL", "length": 1966, "header": "tr|A0A8V0YXU0-1|A0A8V0Z4H3_CHICK Computationally mapped isoform of EMAP like 6 OS=Gallus gallus OX=9031 GN=EML6 PE=3 SV=1 CANONICAL=A0A8V0Z4H3-1" }, "locus": { "chromosome": "3", "start_pos": 2858302, "end_pos": 2740290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040426.1", "url": "https://www.ensembl.org/id/ENSGALT00010040426.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023457.1", "url": "https://www.ensembl.org/id/ENSGALP00010023457.1" } ] } }, { "isoform_ac": "A0A8V0Z4H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3/entry#A0A8V0Z4H3-1", "sequence": { "sequence": "MADRTAPRCRLRLEWVYGYRGHQCRNNLYYTAGKEVVYFVAGVGVVYNTREHSQKFFLGHNDDIISLAVHPDKTLVATGQVGKDPYICVWDSYRVQTVSVLKDAHTHGVACLAFDSDGQRLASVGLDAKNTVCIWDWKRGKLLAAATGHSDRIFDISWDQYQPNRIVSCGVKHIKFWTLCGNALTAKRGIFGKTGDLQTILCLACAKEDITYSGALNGDIYVWKGLNLVRTIQGAHSAGIFSMYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQDSEIFEVLVRERDKPMLIMQGHCEGELWALAVHPKKPLAVTGSDDRSVRLWSLADHALIARCNMEEAVRSVSFSPDGSQLALGMKDGSFIVLRVRDMTEVVHIKDRKEVIHEMKFSPDGSYLAVGSNDGPVDIYAVAQRYKKIGECNKSSSFITHIDWSVDSKFLQTNDGAGERLFYKMPSGKHLTNKDEIKGIHWASWTCVIGSEVNGIWPKYTNVTDVNSVDGNYNSSVLVTGDDFGLVKLFRFPCLRKGAKFRKYVGHSAHVTNVRWSHDFQWVLSTGGADHSVFQWQFIPEGITNGILETAPQEGGIDSYSEESDSDLSDVPELDSDIEQEAQINYDRQVYKEDLPQLKQQSKEKNHSVPFLKRERAPEDSLKLQFIHGYRGYDCRNNLFYTQTGEVVYHIAAVAVVYNRQQHSQRLYLGHDDDILSLSIHPVKDYVATGQVGRDAAIHVWDTQTLKCLSLLKGQHQRGVCALDFSADGKCLASVGLDDNHAIVFWDWKKGEKLATTRGHKDKIFVVKCNPHHVDKLVTVGMKHIKFWQQTGGGFTSRRGTFGSSGKLETMMSVSYGRIEDLVFSGAATGDIFIWKDTLLLKTVKAHDGPVFAMHALDKGFVTGGKDGIVALWDDMFERCLKTYAIKRAALSSSSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPVCATVSDDKTLRIWELSSQHRMLAVRKLKKGGRCCAFSPDGKALAVGLNDGSFLVVNADTVEDMVSFHHRKEMISDIKFSRETGKYLAVASHDNFVDIYNVLTSKRVGICKGASSYITHIDWDSRGKLLQVNSGAKEQLFFEAPRGKRHVIRIAELEKIEWDTWTCVLGPSCEGIWPMHSDVTVVNAATLTKDGTLLATGDDFGFVKLFSYPVKGQHAKFKKYVGHSAQVTNVRWLHNDSVLLTVGGADTALMIWTREFLGIQESKLVDSEESDTDAEEDGGYDSDVAREKAIDYTTKIYAVSIREMEGTKPHQQLKEVSVEERGSRPPVSRAAPQPEKLQKNNINKKRKLVEELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAAAGIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYKNIVATSQIGDMTEFSGTTPTIHVWDAMSKQTISMLRCFHTKGVNYVNFSATGKLLVSVGVDPEHTITVWRWQEGAKVASRGGHLERIFVVEFRPDSDTQFVSVGVKHMKFWTLAGSALLCKKGVIGSMEDAKMQTMLSVAFGANNLTFTGAINGDVYVWKDHFLVRLVAKAHTGPVFTMYTTLRDGLIVTGGKERPTKEGGAVKLWDQEMKRCRAFQLETGQLIECVRSVCRGKGKILVGTKDGEILEVGEKNAASNLLIDCHMEGEIWGLATHPSKDLFISASNDGTARIWDLCDKKLLNKVNLGHPARCAAYSPDGEMVAIGMKNGEFVILLVNSLKVWGKKRDRKSAIQDIRISPDNRFLAVGSQEHTVDFYDLTQGTTLNRIGYCKDIASFVIQMDFSADSRYIQVSTGAYKRQVHEVPLGKQITDTATIEKITWATWTSILGDEVIGIWPRNADKADVNCACVTHAGLNIVTGDDFGLVKLFDFPCTEKFAKHKRYFGHSAHVTNIRFSHDDNYVISTGGDDCSVFVWRCL", "length": 1968, "header": "tr|A0A8V0Z4H3-1|A0A8V0Z4H3_CHICK Isoform 1 of EMAP like 6 OS=Gallus gallus OX=9031 GN=EML6 PE=3 SV=1 CANONICAL=A0A8V0Z4H3-1" }, "locus": { "chromosome": "3", "start_pos": 2858302, "end_pos": 2740290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040418.1", "url": "https://www.ensembl.org/id/ENSGALT00010040418.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023454.1", "url": "https://www.ensembl.org/id/ENSGALP00010023454.1" } ] } }, { "isoform_ac": "E1BZK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3/entry#E1BZK6-1", "sequence": { "sequence": "MADRTAPRCRLRLEWVYGYRGHQCRNNLYYTAGKEVVYFVAGVGVVYNTREHSQKFFLGHNDDIISLAVHPDKTLVATGQVGKDPYICVWDSYRVQTVSVLKDAHTHGVACLAFDSDGQRLASVGLDAKNTVCIWDWKRGKLLAAATGHSDRIFDISWDQYQPNRIVSCGVKHIKFWTLCGNALTAKRGIFGKTGDLQTILCLACAKEDITYSGALNGDIYVWKGLNLVRTIQGAHSAGIFSMYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQDSEIFEVLVRERDKPMLIMQGHCEGELWALAVHPKKPLAVTGSDDRSVRLWSLADHALIARCNMEEAVRSVSFSPDGSQLALGMKDGSFIVLRVRDMTEVVHIKDRKEVIHEMKFSPDGSYLAVGSNDGPVDIYAVAQRYKKIGECNKSSSFITHIDWSVDSKFLQTNDGAGERLFYKMPSGKHLTNKDEIKGIHWASWTCVIGSEVNGIWPKYTNVTDVNSVDGNYNSSVLVTGDDFGLVKLFRFPCLRKGAKFRKYVGHSAHVTNVRWSHDFQWVLSTGGADHSVFQWQFIPEGITNGILETAPQEGGIDSYSEESDSDLSDVPELDSDIEQEAQINYDRQVYKEDLPQLKQQSKEKNHSVPFLKRERAPEDSLKLQFIHGYRGYDCRNNLFYTQTGEVVYHIAAVAVVYNRQQHSQRLYLGHDDDILSLSIHPVKDYVATGQVGRDAAIHVWDTQTLKCLSLLKGQHQRGVCALDFSADGKCLASVGLDDNHAIVFWDWKKGEKLATTRGHKDKIFVVKCNPHHVDKLVTVGMKHIKFWQQTGGGFTSRRGTFGSSGKLETMMSVSYGRIEDLVFSGAATGDIFIWKDTLLLKTVKAHDGPVFAMHALDKGFVTGGKDGIVALWDDMFERCLKTYAIKRAALSSSSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEIDKSGPMTLLVQGHMEGEVWGLAAHPLLPVCATVSDDKTLRIWELSSQHRMLAVRKLKKGGRCCAFSPDGKALAVGLNDGSFLVVNADTVEDMVSFHHRKEMISDIKFSRETGKYLAVASHDNFVDIYNVLTSKRVGICKGASSYITHIDWDSRGKLLQVNSGAKEQLFFEAPRGKRHVIRIAELEKIEWDTWTCVLGPSCEGIWPMHSDVTVVNAATLTKDGTLLATGDDFGFVKLFSYPVKGQHAKFKKYVGHSAQVTNVRWLHNDSVLLTVGGADTALMIWTREFLGIQESKLVDSEESDTDAEEDGGYDSDVAREKAIDYTTKIYAVSIREMEGTKPHQQLKEVSVEERPPVSRAAPQPEKLQKNNINKKRKLVEELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAAAGIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYKNIVATSQIGDMTEFSGTTPTIHVWDAMSKQTISMLRCFHTKGVNYVNFSATGKLLVSVGVDPEHTITVWRWQEGAKVASRGGHLERIFVVEFRPDSDTQFVSVGVKHMKFWTLAGSALLCKKGVIGSMEDAKMQTMLSVAFGANNLTFTGAINGDVYVWKDHFLVRLVAKAHTGPVFTMYTTLRDGLIVTGGKERPTKEGGAVKLWDQEMKRCRAFQLETGQLIECVRSVCRGKGKILVGTKDGEILEVGEKNAASNLLIDCHMEGEIWGLATHPSKDLFISASNDGTARIWDLCDKKLLNKVNLGHPARCAAYSPDGEMVAIGMKNGEFVILLVNSLKVWGKKRDRKSAIQDIRISPDNRFLAVGSQEHTVDFYDLTQGTTLNRIGYCKDIASFVIQMDFSADSRYIQVSTGAYKRQVHEVPLGKQITDTATIEKITWATWTSILGDEVIGIWPRNADKADVNCACVTHAGLNIVTGDDFGLVKLFDFPCTEKFAKHKRYFGHSAHVTNIRFSHDDNYVISTGGDDCSVFVWRCL", "length": 1965, "header": "tr|E1BZK6-1|A0A8V0Z4H3_CHICK Computationally mapped isoform of EMAP like 6 OS=Gallus gallus OX=9031 GN=EML6 PE=3 SV=4 CANONICAL=A0A8V0Z4H3-1" }, "locus": { "chromosome": "3", "start_pos": 2858302, "end_pos": 2740290, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040429.1", "url": "https://www.ensembl.org/id/ENSGALT00010040429.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023459.1", "url": "https://www.ensembl.org/id/ENSGALP00010023459.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1249, "end_pos": 1251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1404, "end_pos": 1406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1479, "end_pos": 1481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1577, "end_pos": 1579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 661, "end_pos": 663, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3" }, { "id": "PF23409", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like first beta-propeller", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 307, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H3" }, { "id": "PF23414", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like second beta-propeller", "eco_id": "ECO_0000259", "start_pos": 328, "end_pos": 592, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1249, "end_pos": 1251 }, { "start_pos": 1404, "end_pos": 1406 }, { "start_pos": 1479, "end_pos": 1481 }, { "start_pos": 1577, "end_pos": 1579 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 517, "end_pos": 519 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 661, "end_pos": 663 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4P3-1", "uniprot_ac": "A0A8V0Z4P3", "uniprot_id": "A0A8V0Z4P3_CHICK", "mass": { "chemical_mass": 32890.0, "monoisotopic_mass": 32890.0 }, "refseq": {}, "gene_names": [ { "name": "VDAC3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3" } ] } ], "protein_names": [ { "name": "Non-selective voltage-gated ion channel VDAC3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane. Forms a high-conducting channel with a stable open state and a voltage-induced closure with a mild preference for anions over cations. Involved in male fertility and sperm mitochondrial sheath formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0YXU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXU7#function" }, { "database": "UniProtKB", "id": "ARBA00049964", "url": "https://www.uniprot.org/uniprotkb/ARBA00049964#function" }, { "database": "UniProtKB", "id": "A0A8V0YXW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXW6#function" }, { "database": "UniProtKB", "id": "A0A8V0Z4P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3#function" }, { "database": "UniProtKB", "id": "A0A8V0Z5Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q6#function" }, { "database": "UniProtKB", "id": "A0A8V0Z5S6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S6#function" }, { "database": "UniProtKB", "id": "A0A8V0YXX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXX1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "VDAC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z4P3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4P3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07306", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07306", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426793", "url": "https://www.ncbi.nlm.nih.gov/gene/426793", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001925", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001925", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SYYHTVR", "url": "https://omabrowser.org/oma/group/SYYHTVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXU7", "url": "https://www.orthodb.org/?gene=A0A8V0YXU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXW6", "url": "https://www.orthodb.org/?gene=A0A8V0YXW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YXX1", "url": "https://www.orthodb.org/?gene=A0A8V0YXX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4P3", "url": "https://www.orthodb.org/?gene=A0A8V0Z4P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5Q6", "url": "https://www.orthodb.org/?gene=A0A8V0Z5Q6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5S6", "url": "https://www.orthodb.org/?gene=A0A8V0Z5S6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11743", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11743", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11743:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11743:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01459", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01459", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5205685", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5689880", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YXU7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXW6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YXX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5S6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5S6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTFMNILQRPCGSLSVKHTEDPMAVPPSYSDLGKAARDVFNKGYGFGMVKLELKTKSSSGVEFTATGSSNTDTGKALGNLETKYKIKDYGLTFIQKWNTDNTLGTEVSMEDQLAEGLKVALDTIFVPNTGKKSGKLKTSYRRDYVNLGCNIDIDLSGPTIYGWAVLGYEGWLAGYQMAFDTAKSKLSQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNNKVETSVNLAWTAGSNNTRFGIAAKYQLDEKTSIGAKVNNASLIGIGYTLALRPGVKLTLSGLIDGKNFSAGGHKVGLGFELEA", "length": 305, "header": "tr|A0A8V0Z4P3-1|A0A8V0Z4P3_CHICK Isoform 1 of Non-selective voltage-gated ion channel VDAC3 OS=Gallus gallus OX=9031 GN=VDAC3 PE=1 SV=1 CANONICAL=A0A8V0Z4P3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YXU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3/entry#A0A8V0YXU7-1", "sequence": { "sequence": "MAVPPSYSDLGKAARDVFNKGYGFGMVKLELKTKSSSGVLEFTATGSSNTDTGKALGNLETKYKIKDYGLTFIQKWNTDNTLGTEVSMEDQLAEGLKVALDTIFVPNTGKKSGKLKTSYRRDYVNLGCNIDIDLSGPTIYGWAVLGYEGWLAGYQMAFDTAKSKLSQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNNKVETSVNLAWTAGSNNTRFGIAAKYQLDEKTSIGAKVNNASLIGIGYTLALRPGVKLTLSGLIDGKNFSAGGHKVGLGFELEA", "length": 284, "header": "tr|A0A8V0YXU7-1|A0A8V0Z4P3_CHICK Computationally mapped isoform of Non-selective voltage-gated ion channel VDAC3 OS=Gallus gallus OX=9031 GN=VDAC3 PE=1 SV=1 CANONICAL=A0A8V0Z4P3-1" }, "locus": { "chromosome": "22", "start_pos": 2912956, "end_pos": 2906498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043517.1", "url": "https://www.ensembl.org/id/ENSGALT00010043517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025875.1", "url": "https://www.ensembl.org/id/ENSGALP00010025875.1" } ] } }, { "isoform_ac": "A0A8V0YXW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3/entry#A0A8V0YXW6-1", "sequence": { "sequence": "MYSIRVMSSIRYLVMGIQQRDGENFPLREEENFCLGTTGFGMVKLELKTKSSSGVEFTATGSSNTDTGKALGNLETKYKIKDYGLTFIQKWNTDNTLGTEVSMEDQLAEGLKVALDTIFVPNTGKKSGKLKTSYRRDYVNLGCNIDIDLSGPTIYGWAVLGYEGWLAGYQMAFDTAKSKLSQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNNKVETSVNLAWTAGSNNTRFGIAAKYQLDEKTSIGAKVNNASLIGIGYTLALRPGVKLTLSGLIDGKNFSAGGHKVGLGFELEA", "length": 299, "header": "tr|A0A8V0YXW6-1|A0A8V0Z4P3_CHICK Computationally mapped isoform of Non-selective voltage-gated ion channel VDAC3 OS=Gallus gallus OX=9031 GN=VDAC3 PE=1 SV=1 CANONICAL=A0A8V0Z4P3-1" }, "locus": { "chromosome": "22", "start_pos": 2912910, "end_pos": 2906498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043534.1", "url": "https://www.ensembl.org/id/ENSGALT00010043534.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025890.1", "url": "https://www.ensembl.org/id/ENSGALP00010025890.1" } ] } }, { "isoform_ac": "A0A8V0YXX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3/entry#A0A8V0YXX1-1", "sequence": { "sequence": "MSIYFRSSRPTGALADADPMAVPPSYSDLGKAARDVFNKGYGFGMVKLELKTKSSSGVLEFTATGSSNTDTGKALGNLETKYKIKDYGLTFIQKWNTDNTLGTEVSMEDQLAEGLKVALDTIFVPNTGKKSGKLKTSYRRDYVNLGCNIDIDLSGPTIYGWAVLGYEGWLAGYQMAFDTAKSKLSQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNNKVETSVNLAWTAGSNNTRFGIAAKYQLDEKTSIGAKVNNASLIGIGYTLALRPGVKLTLSGLIDGKNFSAGGHKVGLGFELEA", "length": 303, "header": "tr|A0A8V0YXX1-1|A0A8V0Z4P3_CHICK Computationally mapped isoform of Non-selective voltage-gated ion channel VDAC3 OS=Gallus gallus OX=9031 GN=VDAC3 PE=1 SV=1 CANONICAL=A0A8V0Z4P3-1" }, "locus": { "chromosome": "22", "start_pos": 2914335, "end_pos": 2906498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043542.1", "url": "https://www.ensembl.org/id/ENSGALT00010043542.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025895.1", "url": "https://www.ensembl.org/id/ENSGALP00010025895.1" } ] } }, { "isoform_ac": "A0A8V0Z4P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3/entry#A0A8V0Z4P3-1", "sequence": { "sequence": "MTFMNILQRPCGSLSVKHTEDPMAVPPSYSDLGKAARDVFNKGYGFGMVKLELKTKSSSGVEFTATGSSNTDTGKALGNLETKYKIKDYGLTFIQKWNTDNTLGTEVSMEDQLAEGLKVALDTIFVPNTGKKSGKLKTSYRRDYVNLGCNIDIDLSGPTIYGWAVLGYEGWLAGYQMAFDTAKSKLSQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNNKVETSVNLAWTAGSNNTRFGIAAKYQLDEKTSIGAKVNNASLIGIGYTLALRPGVKLTLSGLIDGKNFSAGGHKVGLGFELEA", "length": 305, "header": "tr|A0A8V0Z4P3-1|A0A8V0Z4P3_CHICK Isoform 1 of Non-selective voltage-gated ion channel VDAC3 OS=Gallus gallus OX=9031 GN=VDAC3 PE=1 SV=1 CANONICAL=A0A8V0Z4P3-1" }, "locus": { "chromosome": "22", "start_pos": 2913116, "end_pos": 2906498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043527.1", "url": "https://www.ensembl.org/id/ENSGALT00010043527.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025884.1", "url": "https://www.ensembl.org/id/ENSGALP00010025884.1" } ] } }, { "isoform_ac": "A0A8V0Z5Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3/entry#A0A8V0Z5Q6-1", "sequence": { "sequence": "MAVPPSYSDLGKAARDVFNKGYGFGMVKLELKTKSSSGVEFTATGSSNTDTDNTLGTEVSMEDQLAEGLKVALDTIFVPNTGKKSGKLKTSYRRDYVNLGCNIDIDLSGPTIYGWAVLGYEGWLAGYQMAFDTAKSKLSQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNNKVETSVNLAWTAGSNNTRFGIAAKYQLDEKTSIGAKVNNASLIGIGYTLALRPGVKLTLSGLIDGKNFSAGGHKVGLGFELEA", "length": 257, "header": "tr|A0A8V0Z5Q6-1|A0A8V0Z4P3_CHICK Computationally mapped isoform of Non-selective voltage-gated ion channel VDAC3 OS=Gallus gallus OX=9031 GN=VDAC3 PE=1 SV=1 CANONICAL=A0A8V0Z4P3-1" }, "locus": { "chromosome": "22", "start_pos": 2912956, "end_pos": 2906498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043520.1", "url": "https://www.ensembl.org/id/ENSGALT00010043520.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025878.1", "url": "https://www.ensembl.org/id/ENSGALP00010025878.1" } ] } }, { "isoform_ac": "A0A8V0Z5S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3/entry#A0A8V0Z5S6-1", "sequence": { "sequence": "MSIYFRSSRPTGALADADPMAVPPSYSDLGKAARDVFNKGYGFGMVKLELKTKSSSGVEFTATGSSNTDTGKALGNLETKYKIKDYGLTFIQKWNTDNTLGTEVSMEDQLAEGLKVALDTIFVPNTGKKSGKLKTSYRRDYVNLGCNIDIDLSGPTIYGWAVLGYEGWLAGYQMAFDTAKSKLSQNNFALGYKAGDFQLHTNVNDGTEFGGSIYQKVNNKVETSVNLAWTAGSNNTRFGIAAKYQLDEKTSIGAKVNNASLIGIGYTLALRPGVKLTLSGLIDGKNFSAGGHKVGLGFELEA", "length": 302, "header": "tr|A0A8V0Z5S6-1|A0A8V0Z4P3_CHICK Computationally mapped isoform of Non-selective voltage-gated ion channel VDAC3 OS=Gallus gallus OX=9031 GN=VDAC3 PE=1 SV=1 CANONICAL=A0A8V0Z4P3-1" }, "locus": { "chromosome": "22", "start_pos": 2914335, "end_pos": 2906498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043545.1", "url": "https://www.ensembl.org/id/ENSGALT00010043545.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025898.1", "url": "https://www.ensembl.org/id/ENSGALP00010025898.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5205685", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5205685", "resource": "Reactome", "description": "PINK1-PRKN Mediated Mitophagy" }, { "id": "R-GGA-5689880", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5689880", "resource": "Reactome", "description": "Ub-specific processing proteases" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3" } ], "pmid": "" }, { "name": "pore complex", "id": "GO:0046930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3" } ], "pmid": "" }, { "name": "porin activity", "id": "GO:0015288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3" } ], "pmid": "" }, { "name": "voltage-gated monoatomic anion channel activity", "id": "GO:0008308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008308", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": "29823", "name": "", "equation": "chloride(in) = chloride(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0X9Y7-1" ], "evidence": [ { "id": "29823", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29823" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0X9Y7", "gene_name": "CFTR", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A8V0X9Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X9Y7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 289, "end_pos": 291 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z570-1", "uniprot_ac": "A0A8V0Z570", "uniprot_id": "A0A8V0Z570_CHICK", "mass": { "chemical_mass": 197996.0, "monoisotopic_mass": 197996.0 }, "refseq": { "ac": "XP_025008202", "name": "cilia- and flagella-associated protein 65 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008202" }, "gene_names": [ { "name": "CFAP65", "type": "recommended", "evidence": [ { "id": "A0A8V0Z570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" } ] }, { "name": "CCDC108", "type": "synonym", "evidence": [ { "id": "XP_025008202", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008202" } ] }, { "name": "CFAP65", "type": "synonym", "evidence": [ { "id": "XP_025008202", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008202" } ] } ], "protein_names": [ { "name": "Cilia and flagella associated protein 65", "type": "synonym", "evidence": [ { "id": "A0A8V0Z570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 65 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_025008202", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008202" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025008202.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025008202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008202" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CFAP65", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570", "locus": { "chromosome": "7", "start_pos": 21964498, "end_pos": 21947510, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018110", "url": "https://www.ensembl.org/id/ENSGALG00010018110" } ] } } ], "crossref": [ { "id": "424206", "url": "https://www.ncbi.nlm.nih.gov/gene/424206", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056344", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056344", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424206", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424206", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0YYD5", "url": "https://www.orthodb.org/?gene=A0A8V0YYD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z570", "url": "https://www.orthodb.org/?gene=A0A8V0Z570", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZC26", "url": "https://www.orthodb.org/?gene=A0A8V0ZC26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46127:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46127:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22544", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22544", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24507", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24507", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24816", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24816", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025008202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008202", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0YYD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z570-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC26-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATGVMLRGAEPELGGEMLAEVQGEPPNPDPLRRRCCGCARKPSSRKAQKKGTFWGIEVAETLQWRGWELGKEVIKHLVLKNVHEKTQKLSYRCPSTRFFITVFPQPIALSPGMSLTLPVIFRPTEKRDYEDSICFQKAEGEFSVTLRAVLPHPCLSFPSAVQLPLCAVHSAAETTFTVRNVGDLTTVFAWETPSPFSMTPEHGVLSVGAECTVKVLFQPKAAAVCNVIATCWFGVEEKQKRTMQLRAQAKYPYLQVNVPGEQHKGAQPGKLQDVLCFGSVPVGTSVEKCVEILNMSAVDAPCMIERAKDPLLQDHVFSCDVSHAVVPAKGKLALCIRFQPQAVGEHSTDYFTVTPTGCLQQTVLKMVGSCKGPLVSLHQSSVDFDWINLGESSTQMLKISNVSDVPAYYQFDIDGRGSVFSLDRPCGVLEGTTTLVLKVTFRPAHPISYHRRVVCLVHHQEPLYVDFFGTCHSDTAKPAILQARHLSWYRTNTVRGLTFYPPDILSVMLKDGKLLMDEKRALMLLPEIPLDKPPKEYTEASSMSEYFYDGISSDLALFPPHVSVSPREHDFGRCVPLCKAEPLPLCVTNHTKGKITVAWTPSYGSAFQVTPESCDIPPLKSSAFRVLFQPTQLNSLYAAELEGFAFYKVLRQYSNIEEDATICPPWCLTIRLRAHTYEAKREHFIPQYLLDVPKTFPPVASDTDTYCSALLSNTGTSMITFSVNQAACPSVLVKPHSGHIMPGGHQIFFLSTRPVNTVSQQHILPLQLNSYPGYTKEIVLRSCAESLLLLLEGDGKLYFKPVCIGTSSTQRYTIKNCTRLPMAFTWKIHLSDSKLLSVRPAAGLLQPYEAMAQAWTFTPDNVTKYLLRAVVFVGWESPAPVSPQSIHYNLRIIGEGALGTIRAQKEHVDLGNVLVGNLKDCSMVLLNDGICSLQYILSVEQLITGLCDPEEVCSDPMALELEHSRGTIPARSKAFVRVTVRPARQLHYTWSISYAICTPAVPDLASTKAEQHPLCCIEATGVHPTIRIAAACSAGSTSGISRLLLWRLLSLDTLNEYLQRDPAPSELTYRVPTRHSTCLIPPIYTPLQLDFNFGAAPIGSEPALVMLLLVNNGVVPVEWAFLFPSDQKMDMEHWAEDANLSPRELHQMRIQDNQLFSVSPKSGKLLPGQEEAVQLSHRHDFVGTDHLPVLLKASYGHEILLNFRGVTVEKEQRYVHFASSKHLLTPIAIGTSHPPIQIYELYNGGSTTVMFEVQLDSITRVQKDNYQHPVFICLTPRGEIAPGTTGHIEWIFSPLEARTYLVDVPIHILGGDSALITFQGEGYDPKATGESATFREVLSPSVLLGSTKLTVPGQAASLSHHRICFGNIPDRTRASRLVFLNNISEDKAVVFTWRTGSVKDSEVLQIVPEQGVVQPRGSTPCFITLQPSGRVSLYSADLVCEVYIQESLVQYERDLQEWEREKERQAVEFTITEQDLRAEKKPRPPAGRSSDSAETANLCEPSAVVRKYKTLPPVKNHPAANQPAGHLQRRLLSSKEASHVWVKPEPPRPILLHLDVTARSHSTEDFFSNFTSEFPKYFLPRPSIHQLLFVDGSVDRDRMEKDPEWLSLATASKEELQIVTDVLIGVIRDLLENTQFHDAVRRSLQEPIPYFSQFQREETAKTQHRGQCSTIPSSLSASPDLFTEENGEKKETSQESSPSNDVLGSWEGLSEVLRHEQLREQKMMMKRQPAFGSLVEMVLENTLQNILVEASCGEVVLTAQPKVIALPPRPFRRTASPAP", "length": 1780, "header": "tr|A0A8V0Z570-1|A0A8V0Z570_CHICK Isoform 1 of Cilia and flagella associated protein 65 OS=Gallus gallus OX=9031 GN=CFAP65 PE=4 SV=1 CANONICAL=A0A8V0Z570-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570/entry#A0A8V0YYD5-1", "sequence": { "sequence": "MLAEVQGEPPNPDPLRRRCCGCARKPSSRKAQKKGTFWGIEVAETLQWRGWELGKEVIKHLVLKNVHEKTQKLSYRCPSTRFFITVFPQPIALSPGMSLTLPVIFRPTEKRDYEDSICFQKAEGEFSVTLRAVLPHPCLSFPSAVQLPLCAVHSAAETTFTVRNVGDLTTVFAWETPSPFSMTPEHGVLSVGAECTVKVLFQPKAAAVCNVIATCWFGVEEKQKRTMQLRAQAKYPYLQVNVPGEQHKGAQPGKLQDVLCFGSVPVGTSVEKCVEILNMSAVDAPCMIERAKDPLLQDHVFSCDVSHAVVPAKGKLALCIRFQPQAVGEHSTDYFTVTPTGCLQQTVLKMVGSCKGPLVSLHQSSVDFDWINLGESSTQMLKISNVSDVPAYYQFDIDGRGSVFSLDRPCGVLEGTTTLVLKVTFRPAHPISYHRRVVCLVHHQEPLYVDFFGTCHSDTAKPAILQARHLSWYRTNTVRGLTFYPPDILSVMLKDGKLLMDEKRALMLLPEIPLDKPPKEYTEASSMSEYFYDGISSDLALFPPHVSVSPREHDFGRCVPLCKAEPLPLCVTNHTKGKITVAWTPSYGSAFQVTPESCDIPPLKSSAFRVLFQPTQLNSLYAAELEGFAFYKVLRQYSNIEEDATICPPWCLTIRLRAHTYEAKREHFIPQYLLDVPKTFPPVASDTDTYCSALLSNTGTSMITFSVNQAACPSVLVKPHSGHIMPGGHQIFFLSTRPVNTVSQQHILPLQLNSYPGYTKEIVLRSCAESLLLLLEGDGKLYFKPVCIGTSSTQRYTIKNCTRLPMAFTWKIHLSDSKLLSVRPAAGLLQPYEAMAQAWTFTPDNVTKYLLRAVVFVGWESPAPVSPQSIHYNLRIIGEGALGTIRAQKEHVDLGNVLVGNLKDCSMVLLNDGICSLQYILSVEQLITGLCDPEEVCSDPMALELEHSRGTIPARSKAFVRVTVRPARQLHYTWSISYAICTPAVPDLASTKAEQHPLCCIEATGVHPTIRIAAACSAGSTSGISRLLLWRLLSLDTLNEYLQRDPAPSELTYRVPTRHSTCLIPPIYTPLQLDFNFGAAPIGSEPALVMLLLVNNGVVPVEWAFLFPSDQKMDMEHWAEDANLSPRELHQMRIQDNQLFSVSPKSGKLLPGQEEAVQLSHRHDFVGTDHLPVLLKASYGHEILLNFRGVTVEKEQRYVHFASSKHLLTPIAIGTSHPPIQIYELYNGGSTTVMFEVQLDSITRVQKDNYQHPVFICLTPRGEIAPGTTGHIEWIFSPLEARTYLVDVPIHILGGDSALITFQGEGYDPKATGESATFREVLSPSVLLGSTKLTVPGQAASLSHHRICFGNIPDRTRASRLVFLNNISEDKAVVFTWRTGSVKDSEVLQIVPEQGVVQPRGSTPCFITLQPSGRVSLYSADLVCEVYIQESLVQYERDLQEWEREKERQAVEFTITEQDLRAEKKPRPPAGVSVAKGGTLPPVKNHPAANQPAGHLQRRLLSSKEASHVWVKPEPPRPILLHLDVTARSHSTEDFFSNFTSEFPKYFLPRPSIHQLLFVDGSVDRDRMEKDPEWLSLATASKEELQIVTDVLIGVIRDLLENTQFHDAVRRSLQEPIPYFSQFQREETAKTQHRGQCSTIPSSLSASPDLFTEENGEKKETSQESSPSNDVLGSWEGLSEVLRHEQLREQKMMMKRQPAFGSLVEMVLENTLQNILVEASCGEVVLTAQPKVIALPPRPFRSLARLRSQCQGCLCRRWNPTPKPMLLVLSQAPWE", "length": 1775, "header": "tr|A0A8V0YYD5-1|A0A8V0Z570_CHICK Computationally mapped isoform of Cilia and flagella associated protein 65 OS=Gallus gallus OX=9031 GN=CFAP65 PE=4 SV=1 CANONICAL=A0A8V0Z570-1" }, "locus": { "chromosome": "7", "start_pos": 21963805, "end_pos": 21947865, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043819.1", "url": "https://www.ensembl.org/id/ENSGALT00010043819.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026063.1", "url": "https://www.ensembl.org/id/ENSGALP00010026063.1" } ] } }, { "isoform_ac": "A0A8V0Z570-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570/entry#A0A8V0Z570-1", "sequence": { "sequence": 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"length": 1780, "header": "tr|A0A8V0Z570-1|A0A8V0Z570_CHICK Isoform 1 of Cilia and flagella associated protein 65 OS=Gallus gallus OX=9031 GN=CFAP65 PE=4 SV=1 CANONICAL=A0A8V0Z570-1" }, "locus": { "chromosome": "7", "start_pos": 21964196, "end_pos": 21947559, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043826.1", "url": "https://www.ensembl.org/id/ENSGALT00010043826.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026067.1", "url": "https://www.ensembl.org/id/ENSGALP00010026067.1" } ] } }, { "isoform_ac": "A0A8V0ZC26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570/entry#A0A8V0ZC26-1", "sequence": { "sequence": "MSLTLPVIFRPTEKRDYEDSICFQKAEGEFSVTLRAVLPHPCLSFPSAVQLPLCAVHSAAETTFTVRNVGDLTTVFAWETPSPFSMTPEHGVLSVGAECTVKVLFQPKAAAVCNVIATCWFGVEEKQKRTMQLRAQAKYPYLQVNVPGEQHKGAQPGKLQDVLCFGSVPVGTSVEKCVEILNMSAVDAPCMIERAKDPLLQDHVFSCDVSHAVVPAKGKLALCIRFQPQAVGEHSTDYFTVTPTGCLQQTVLKMVGSCKGPLVSLHQSSVDFDWINLGESSTQMLKISNVSDVPAYYQFDIDGRGSVFSLDRPCGVLEGTTTLVLKVTFRPAHPISYHRRVVCLVHHQEPLYVDFFGTCHSDTAKPAILQARHLSWYRTNTVRGLTFYPPDILSVMLKDGKLLMDEKRALMLLPEIPLDKPPKEYTEASSMSEYFYDGISSDLALFPPHVSVSPREHDFGRCVPLCKAEPLPLCVTNHTKGKITVAWTPSYGSAFQVTPESCDIPPLKSSAFRVLFQPTQLNSLYAAELEGFAFYKVLRQYSNIEEDATICPPWCLTIRLRAHTYEAKREHFIPQYLLDVPKTFPPVASDTDTYCSALLSNTGTSMITFSVNQAACPSVLVKPHSGHIMPGGHQIFFLSTRPVNTVSQQHILPLQLNSYPGYTKEIVLRSCAESLLLLLEGDGKLYFKPVCIGTSSTQRYTIKNCTRLPMAFTWKIHLSDSKLLSVRPAAGLLQPYEAMAQAWTFTPDNVTKYLLRAVVFVGWESPAPVSPQSIHYNLRIIGEGALGTIRAQKEHVDLGNVLVGNLKDCSMVLLNDGICSLQYILSVEQLITGLCDPEEVCSDPMALELEHSRGTIPARSKAFVRVTVRPARQLHYTWSISYAICTPAVPDLASTKAEQHPLCCIEATGVHPTIRIAAACSAGSTSGISRLLLWRLLSLDTLNEYLQRDPAPSELTYRVPTRHSTCLIPPIYTPLQLDFNFGAAPIGSEPALVMLLLVNNGVVPVEWAFLFPSDQKMDMEHWAEDANLSPRELHQMRIQDNQLFSVSPKSGKLLPGQEEAVQLSHRHDFVGTDHLPVLLKASYGHEILLNFRGVTVEKEQRYVHFASSKHLLTPIAIGTSHPPIQIYELYNGGSTTVMFEVQLDSITRVQKDNYQHPVFICLTPRGEIAPGTTGHIEWIFSPLEARTYLVDVPIHILGGDSALITFQGEGYDPKATGESATFREVLSPSVLLGSTKLTVPGQAASLSHHRICFGNIPDRTRASRLVFLNNISEDKAVVFTWRTGSVKDSEVLQIVPEQGVVQPRGSTPCFITLQPSGRVSLYSADLVCEVYIQESLVQYERDLQEWEREKERQAVEFTITEQDLRAEKKPRPPAGRSSDSAETANLCEPSAVVRKYKTLPPVKNHPAANQPAGHLQRRLLSSKEASHVWVKPEPPRPILLHLDVTARSHSTEDFFSNFTSEFPKYFLPRPSIHQLLFVDGSVDRDRMEKDPEWLSLATASKEELQIVTDVLIGVIRDLLENTQFHDAVRRSLQEPIPYFSQFQREETAKTQHRGQCSTIPSSLSASPDLFTEENGEKKETSQESSPSNDVLGSWEGLSEVLRHEQLREQKMMMKRQPAFGSLVEMVLENTLQNILVEASCGEVVLTAQPKVIALPPRPFRR", "length": 1661, "header": "tr|A0A8V0ZC26-1|A0A8V0Z570_CHICK Computationally mapped isoform of Cilia and flagella associated protein 65 OS=Gallus gallus OX=9031 GN=CFAP65 PE=4 SV=1 CANONICAL=A0A8V0Z570-1" }, "locus": { "chromosome": "7", "start_pos": 21963655, "end_pos": 21949094, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043802.1", "url": "https://www.ensembl.org/id/ENSGALT00010043802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026053.1", "url": "https://www.ensembl.org/id/ENSGALP00010026053.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 355, "start_aa": "Thr", "end_pos": 355, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr355", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424206", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424206", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" } ], "pmid": "" }, { "name": "axonemal central apparatus", "id": "GO:1990716", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990716", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" } ], "pmid": "" }, { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" } ], "pmid": "" }, { "name": "sperm midpiece", "id": "GO:0097225", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" } ], "pmid": "" }, { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" } ], "pmid": "" }, { "name": "sperm mitochondrial sheath assembly", "id": "GO:0120317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120317", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z570", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1140, "end_pos": 1142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1383, "end_pos": 1385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1570, "end_pos": 1572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 817, "end_pos": 819, "annotation": "n_glycosylation_sequon" }, { "start_pos": 862, "end_pos": 864, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" }, { "id": "PF15780", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15780" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Abnormal spindle-like microcephaly-associated protein ASH", "eco_id": "ECO_0000259", "start_pos": 272, "end_pos": 357, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" }, { "id": "PF25248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP65 eight Ig-like", "eco_id": "ECO_0000259", "start_pos": 899, "end_pos": 1022, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" }, { "id": "PF24507", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24507" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP65 fourth Ig-like", "eco_id": "ECO_0000259", "start_pos": 382, "end_pos": 476, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z570", "database": 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF24816" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CFAP65-like ninth Ig-like", "eco_id": "ECO_0000259", "start_pos": 1025, "end_pos": 1206, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z570", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z570" }, { "id": "PF22544", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22544" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HYDIN/VesB/CFA65-like Ig-like", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 240, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 355 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1140, "end_pos": 1142 }, { "start_pos": 1383, "end_pos": 1385 }, { "start_pos": 1570, "end_pos": 1572 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 590, "end_pos": 592 }, { "start_pos": 817, "end_pos": 819 }, { "start_pos": 862, "end_pos": 864 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8V0Z554", "uniprot_id": "A0A8V0Z554_CHICK", "mass": { "chemical_mass": 67616.0, "monoisotopic_mass": 67616.0 }, "refseq": {}, "gene_names": [ { "name": "BTRC", "type": "recommended", "evidence": [ { "id": "A0A8V0Z554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ] } ], "protein_names": [ { "name": "Beta-transducin repeat containing E3 ubiquitin protein ligase", "type": "synonym", "evidence": [ { "id": "A0A8V0Z554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": 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"A0A8V0Z551-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z551-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z554-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z559", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z559", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z559-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z559-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z673", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z673", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z673-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z673-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z682", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z682", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z682-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z682-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z687", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z687", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z687-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z687-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC36", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC40", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGEECSMPRSLWLGCSSLADSMPSLRCLYNPGTGALPAFQNSSEREDCNNDEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLGSTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDALWRGLSERRGWGQYLFKNKPPDGTAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAESTRSPSRTYTYISR", "length": 594, "header": "tr|A0A8V0Z554-1|A0A8V0Z554_CHICK Isoform 1 of Beta-transducin repeat containing E3 ubiquitin protein ligase OS=Gallus gallus OX=9031 GN=BTRC PE=4 SV=1 CANONICAL=A0A8V0Z554-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554/entry#A0A8V0YYE1-1", "sequence": { "sequence": "MAMDPAEAVLQEKALKFMPRIHMPKDGFQLISSGYQAWLKQCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALPAFQNSSEREDCNNDEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLGSTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDALWRGLSERRGWGQYLFKNKPPDGTAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAESTRSPSRTYTYISR", "length": 630, "header": "tr|A0A8V0YYE1-1|A0A8V0Z554_CHICK Computationally mapped isoform of Beta-transducin repeat containing E3 ubiquitin protein ligase OS=Gallus gallus OX=9031 GN=BTRC PE=4 SV=1 CANONICAL=A0A8V0Z554-1" }, "locus": { "chromosome": "6", "start_pos": 23740611, "end_pos": 23628734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043829.1", "url": "https://www.ensembl.org/id/ENSGALT00010043829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026068.1", "url": "https://www.ensembl.org/id/ENSGALP00010026068.1" } ] } }, { "isoform_ac": "A0A8V0YYE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554/entry#A0A8V0YYE7-1", "sequence": { "sequence": "MAMDPAEAVLQEKALKFMNSSEREDCNNDEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLGSTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDALWRGLSERRGWGQYLFKNKPPDGTAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAESTRSPSRTYTYISR", "length": 571, "header": "tr|A0A8V0YYE7-1|A0A8V0Z554_CHICK Computationally mapped isoform of Beta-transducin repeat containing E3 ubiquitin protein ligase OS=Gallus gallus OX=9031 GN=BTRC PE=4 SV=1 CANONICAL=A0A8V0Z554-1" }, "locus": { "chromosome": "6", "start_pos": 23740611, "end_pos": 23628734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043838.1", "url": "https://www.ensembl.org/id/ENSGALT00010043838.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026073.1", "url": "https://www.ensembl.org/id/ENSGALP00010026073.1" } ] } }, { "isoform_ac": "A0A8V0Z551-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554/entry#A0A8V0Z551-1", "sequence": { "sequence": "MGTTARWEGARGLQLPPALGEGIALLIHLLAQGGWNQTYNSCARLCLNQETVCLGSTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDALWRGLSERRGWGQYLFKNKPPDGTAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAESTRSPSRTYTYISR", "length": 564, "header": "tr|A0A8V0Z551-1|A0A8V0Z551_CHICK Computationally mapped isoform of Beta-transducin repeat containing E3 ubiquitin protein ligase OS=Gallus gallus OX=9031 GN=BTRC PE=4 SV=1 CANONICAL=A0A8V0Z554-1" }, "locus": { "chromosome": "6", "start_pos": 23686009, "end_pos": 23628734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043793.1", "url": "https://www.ensembl.org/id/ENSGALT00010043793.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026046.1", "url": "https://www.ensembl.org/id/ENSGALP00010026046.1" } ] } }, { "isoform_ac": "A0A8V0Z554-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554/entry#A0A8V0Z554-1", "sequence": { "sequence": "MDGEECSMPRSLWLGCSSLADSMPSLRCLYNPGTGALPAFQNSSEREDCNNDEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLGSTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDALWRGLSERRGWGQYLFKNKPPDGTAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAESTRSPSRTYTYISR", "length": 594, "header": "tr|A0A8V0Z554-1|A0A8V0Z554_CHICK Isoform 1 of Beta-transducin repeat containing E3 ubiquitin protein ligase OS=Gallus gallus OX=9031 GN=BTRC PE=4 SV=1 CANONICAL=A0A8V0Z554-1" }, "locus": { "chromosome": "6", "start_pos": 23708025, "end_pos": 23628734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043798.1", "url": "https://www.ensembl.org/id/ENSGALT00010043798.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026051.1", "url": "https://www.ensembl.org/id/ENSGALP00010026051.1" } ] } }, { "isoform_ac": "A0A8V0Z559-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554/entry#A0A8V0Z559-1", "sequence": { "sequence": "MAMDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALPAFQNSSEREDCNNDEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLGSTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDALWRGLSERRGWGQYLFKNKPPDGTAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAESTRSPSRTYTYISR", "length": 607, "header": "tr|A0A8V0Z559-1|A0A8V0Z559_CHICK Computationally mapped isoform of Beta-transducin repeat containing E3 ubiquitin protein ligase OS=Gallus gallus OX=9031 GN=BTRC PE=4 SV=1 CANONICAL=A0A8V0Z554-1" }, "locus": { "chromosome": "6", "start_pos": 23740611, "end_pos": 23628734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043806.1", "url": "https://www.ensembl.org/id/ENSGALT00010043806.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026056.1", "url": "https://www.ensembl.org/id/ENSGALP00010026056.1" } ] } }, { "isoform_ac": "A0A8V0Z673-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554/entry#A0A8V0Z673-1", "sequence": { "sequence": "MAMDPAEAVLQEKALKFMPRIHMPKDGFQLISSGYQAWLKQCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALPAFQTYNSCARLCLNQETVCLGSTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDALWRGLSERRGWGQYLFKNKPPDGTAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAESTRSPSRTYTYISR", "length": 604, "header": "tr|A0A8V0Z673-1|A0A8V0Z554_CHICK Computationally mapped isoform of Beta-transducin repeat containing E3 ubiquitin protein ligase OS=Gallus gallus OX=9031 GN=BTRC PE=4 SV=1 CANONICAL=A0A8V0Z554-1" }, "locus": { "chromosome": "6", "start_pos": 23740611, "end_pos": 23628734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043816.1", "url": "https://www.ensembl.org/id/ENSGALT00010043816.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026061.1", "url": "https://www.ensembl.org/id/ENSGALP00010026061.1" } ] } }, { "isoform_ac": "A0A8V0Z682-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554/entry#A0A8V0Z682-1", "sequence": { "sequence": "MSSKCLAAPGESLLWNSSEREDCNNDEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLGSTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDALWRGLSERRGWGQYLFKNKPPDGTAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAESTRSPSRTYTYISR", "length": 568, "header": "tr|A0A8V0Z682-1|A0A8V0Z554_CHICK Computationally mapped isoform of Beta-transducin repeat containing E3 ubiquitin protein ligase OS=Gallus gallus OX=9031 GN=BTRC PE=4 SV=1 CANONICAL=A0A8V0Z554-1" }, "locus": { "chromosome": "6", "start_pos": 23739943, "end_pos": 23628734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043836.1", "url": "https://www.ensembl.org/id/ENSGALT00010043836.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026071.1", "url": "https://www.ensembl.org/id/ENSGALP00010026071.1" } ] } }, { "isoform_ac": "A0A8V0Z687-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554/entry#A0A8V0Z687-1", "sequence": { "sequence": "MAMDPAEAVLQEKALKFMLLVGKPKPTPEQLREGREDREPLMKRSTTPATPTLLILLVFMVTGGGEGVHLLQQPRNVWVTWVNLTGRTDFCLSLQSATSPFRTCLVGLPSYQLEEFRGYTVNYIGCKNDIDAATQTACLIQSLNRTLPWDPQELDILGSQMIKNGTTRTCVTFGSMCYKENNHSRVCHNFDGNFNGTGGVEAELRDLIAKWSKDDPRIRPYVNRSWTVNSSEREDCNNDEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLGSTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDALWRGLSERRGWGQYLFKNKPPDGTAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAESTRSPSRTYTYISR", "length": 781, "header": "tr|A0A8V0Z687-1|A0A8V0Z554_CHICK Computationally mapped isoform of Beta-transducin repeat containing E3 ubiquitin protein ligase OS=Gallus gallus OX=9031 GN=BTRC PE=4 SV=1 CANONICAL=A0A8V0Z554-1" }, "locus": { "chromosome": "6", "start_pos": 23740611, "end_pos": 23628734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043843.1", "url": "https://www.ensembl.org/id/ENSGALT00010043843.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026076.1", "url": "https://www.ensembl.org/id/ENSGALP00010026076.1" } ] } }, { "isoform_ac": "A0A8V0ZC36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554/entry#A0A8V0ZC36-1", "sequence": { "sequence": "MAMDPAEAVLQEKALKFMKLLVGKPKPTPEQLREGREDREPLMKRSTTPATPTLLILLVFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALPAFQNSSEREDCNNDEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLGSTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDALWRGLSERRGWGQYLFKNKPPDGTAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAESTRSPSRTYTYISR", "length": 650, "header": "tr|A0A8V0ZC36-1|A0A8V0Z554_CHICK Computationally mapped isoform of Beta-transducin repeat containing E3 ubiquitin protein ligase OS=Gallus gallus OX=9031 GN=BTRC PE=4 SV=1 CANONICAL=A0A8V0Z554-1" }, "locus": { "chromosome": "6", "start_pos": 23740611, "end_pos": 23628734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043821.1", "url": "https://www.ensembl.org/id/ENSGALT00010043821.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026064.1", "url": "https://www.ensembl.org/id/ENSGALP00010026064.1" } ] } }, { "isoform_ac": "A0A8V0ZC40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554/entry#A0A8V0ZC40-1", "sequence": { "sequence": "MAMDPAEAVLQEKALKFMPRIHMPKDGFQLISSGYQAWLKQNSSEREDCNNDEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLGSTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDALWRGLSERRGWGQYLFKNKPPDGTAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNAGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAESTRSPSRTYTYISR", "length": 594, "header": "tr|A0A8V0ZC40-1|A0A8V0Z554_CHICK Computationally mapped isoform of Beta-transducin repeat containing E3 ubiquitin protein ligase OS=Gallus gallus OX=9031 GN=BTRC PE=4 SV=1 CANONICAL=A0A8V0Z554-1" }, "locus": { "chromosome": "6", "start_pos": 23740611, "end_pos": 23628734, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043833.1", "url": "https://www.ensembl.org/id/ENSGALT00010043833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026069.1", "url": "https://www.ensembl.org/id/ENSGALP00010026069.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-1170546", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1170546", "resource": "Reactome", "description": "Prolactin receptor signaling" }, { "id": "R-GGA-174113", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-174113", "resource": "Reactome", "description": "SCF-beta-TrCP mediated degradation of Emi1" }, { "id": "R-GGA-195253", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-195253", "resource": "Reactome", "description": "Degradation of beta-catenin by the destruction complex" }, { "id": "R-GGA-3769402", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-3769402", "resource": "Reactome", "description": "Deactivation of the beta-catenin transactivating complex" }, { "id": "R-GGA-5610780", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610780", "resource": "Reactome", "description": "Degradation of GLI1 by the proteasome" }, { "id": "R-GGA-5610785", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5610785", "resource": "Reactome", "description": "GLI3 is processed to GLI3R by the proteasome" }, { "id": "R-GGA-69601", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69601", "resource": "Reactome", "description": "Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A" }, { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-9020702", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9020702", "resource": "Reactome", "description": "Interleukin-1 signaling" }, { "id": "R-GGA-9762114", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9762114", "resource": "Reactome", "description": "GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" }, { "id": "R-GGA-9929356", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9929356", "resource": "Reactome", "description": "GSK3B-mediated proteasomal degradation of PD-L1(CD274)" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "protein phosphorylated amino acid binding", "id": "GO:0045309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045309", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "ubiquitin ligase activator activity", "id": "GO:1990757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990757", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "regulation of canonical Wnt signaling pathway", "id": "GO:0060828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060828", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "non-canonical NF-kappaB signal transduction", "id": "GO:0038061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038061", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "negative regulation of T cell receptor signaling pathway", "id": "GO:0050860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050860", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "positive regulation of circadian rhythm", "id": "GO:0042753", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042753", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z554" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3G0-1", "uniprot_ac": "A0A8V0Z3G0", "uniprot_id": "A0A8V0Z3G0_CHICK", "mass": { "chemical_mass": 97852.0, "monoisotopic_mass": 97852.0 }, "refseq": {}, "gene_names": [ { "name": "ZBTB17", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 17", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 151", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein Z13", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZBTB17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0", "locus": { "chromosome": "21", "start_pos": 4298883, "end_pos": 4305017, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016577", "url": "https://www.ensembl.org/id/ENSGALG00010016577" } ] } } ], "crossref": [ { "id": "A0A8V0Z3G0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3G0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18206", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18206", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396541", "url": "https://www.ncbi.nlm.nih.gov/gene/396541", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:396541", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396541", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DKGHKCP", "url": "https://omabrowser.org/oma/group/DKGHKCP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYF1", "url": "https://www.orthodb.org/?gene=A0A8V0YYF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3F4", "url": "https://www.orthodb.org/?gene=A0A8V0Z3F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3G0", "url": "https://www.orthodb.org/?gene=A0A8V0Z3G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0YYF1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YYF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3F4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFPQHSRQVLEQLNQLRQLGLLCDCTFVVDGINFKAHKAVLAACSEYFRMLFVDQKEDVVHLDISNVAGLGQVLEFMYTAKLSLNPDNVEDVLAVAGFLQMREIVNACNALKSLTVLAESPVESRELLTELGVEKVIVEGKTAAAVTQGDSDKPKQVPPNQEGKEEAPVGTAAQPKEPAEQPDAKEGPAEGQQPGGVDNAAEASPAAVSPSRPQPAESEVGNSSPGEKGSDAPSTEARGMELEGKEEEGEAMVEDEEEAKIPKAAQPKSESKENAEDNESGSTDSGQENSGETRLLRSGTYSDRTESKAYGSVTHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECNKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHTGEAKYRCDDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCVHCQRQFADPGALQRHVRIHTGEKPCQCLICGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCTVCNKAFVNVGDLSKHIIIHTGEKPFLCDKCGRGFNRVDNLRSHVKTVHQGKAGMKILEPEDGSELNIVTVASDDMVTLATEALAATAVTQLTVVPVAAAVTADETEALKAEITKAVKQVQEAGEEGRGPASRSPGPRPAAATPRASPLPLQTPTLRSFTPAIPAGRNSWMPPAWRSTSASTQPRRSSCSRPTRTFTSSTGPPLPPGRPSRSSLPPSCSSAPVTAPKRPPPPPWPLCPLLGRARRLLSDPPAPPRLYLKSAAWKRCKKCISGRRERRNKLQYFLKRVVESTASQRSA", "length": 895, "header": "tr|A0A8V0Z3G0-1|A0A8V0Z3G0_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 17 OS=Gallus gallus OX=9031 GN=ZBTB17 PE=3 SV=1 CANONICAL=A0A8V0Z3G0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0YYF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0/entry#A0A8V0YYF1-1", "sequence": { "sequence": "MDFPQHSRQVLEQLNQLRQLGLLCDCTFVVDGINFKAHKAVLAACSEYFRMLFVDQKEDVVHLDISNVAGLGQVLEFMYTAKLSLNPDNVEDVLAVAGFLQMREIVNACNALKSLTVLAESPVESRELLTELGVEKEGKEEAPVGTAAQPKEPAEQPDAKEGPAEGVDNAAEASPAAVSPSRPQPAESEVGNSSPGEKGSDAPSTEARGMELEGKEEEGEAMVEDEEEAKIPKAAQPKSESKENAEDNESGSTDSGQENSGETRLLRSGTYSDRTESKAYGSVTHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECNKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHTGEAKYRCDDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCVHCQRQFADPGALQRHVRIHTGEKPCQCLICGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCTVCNKAFVNVGDLSKHIIIHTGEKPFLCDKCGRGFNRVDNLRSHVKTVHQGKAGMKILEPEDGSELNIVTVASDDMVTLATEALAATAVTQLTVVPVAAAVTADETEALKAEITKAVKQVQEADPNTQILYACDSCGEKFLDATSLAQHVRIHTAQALVMFQADTDFYQQYGAAAATWQTEQVIPATELLFRPRDSPQEAPAAPLAPVPLAGEGQAPAE", "length": 786, "header": "tr|A0A8V0YYF1-1|A0A8V0Z3G0_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 17 OS=Gallus gallus OX=9031 GN=ZBTB17 PE=3 SV=1 CANONICAL=A0A8V0Z3G0-1" }, "locus": { "chromosome": "21", "start_pos": 4302913, "end_pos": 4299031, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039935.1", "url": "https://www.ensembl.org/id/ENSGALT00010039935.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023122.1", "url": "https://www.ensembl.org/id/ENSGALP00010023122.1" } ] } }, { "isoform_ac": "A0A8V0Z3F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0/entry#A0A8V0Z3F4-1", "sequence": { "sequence": "MDFPQHSRQVLEQLNQLRQLGLLCDCTFVVDGINFKAHKAVLAACSEYFRMLFVDQKEDVVHLDISNVAGLGQVLEFMYTAKLSLNPDNVEDVLAVAGFLQMREIVNACNALKSLTVLAESPVESRELLTELGVEKVIVEGKTAAAVTQGDSDKPKQVPPNQEGKEEAPVGTAAQPKEPAEQPDAKEGPAEGQQPGGVDNAAEASPAAVSPSRPQPAESEVGNSSPGEKGSDAPSTEARGMELEGKEEEGEAMVEDEEEAKIPKAAQPKSESKENAEDNESGSTDSGQENSGETRLLRSGTYSDRTESKAYGSVTHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECNKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHTGEAKYRCDDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCVHCQRQFADPGALQRHVRIHTGEKPCQCLICGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCTVCNKAFVNVGDLSKHIIIHTGEKPFLCDKCGRGFNRVDNLRSHVKTVHQGKAGMKILEPEDGSELNIVTVASDDMVTLATEALAATAVTQLTVVPVAAAVTADETEALKAEITKAVKQVQEADPNTQILYACDSCGEKFLDATSLAQHVRIHTAQALVMFQADTDFYQQYGAAAATWQTEQVIPATELLFRPRDSPQEAPAAPLAPVPLAGEGQAPAE", "length": 817, "header": "tr|A0A8V0Z3F4-1|A0A8V0Z3F4_CHICK Computationally mapped isoform of Zinc finger and BTB domain-containing protein 17 OS=Gallus gallus OX=9031 GN=ZBTB17 PE=3 SV=1 CANONICAL=A0A8V0Z3G0-1" }, "locus": { "chromosome": "21", "start_pos": 4302913, "end_pos": 4299031, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039940.1", "url": "https://www.ensembl.org/id/ENSGALT00010039940.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023126.1", "url": "https://www.ensembl.org/id/ENSGALP00010023126.1" } ] } }, { "isoform_ac": "A0A8V0Z3G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0/entry#A0A8V0Z3G0-1", "sequence": { "sequence": "MDFPQHSRQVLEQLNQLRQLGLLCDCTFVVDGINFKAHKAVLAACSEYFRMLFVDQKEDVVHLDISNVAGLGQVLEFMYTAKLSLNPDNVEDVLAVAGFLQMREIVNACNALKSLTVLAESPVESRELLTELGVEKVIVEGKTAAAVTQGDSDKPKQVPPNQEGKEEAPVGTAAQPKEPAEQPDAKEGPAEGQQPGGVDNAAEASPAAVSPSRPQPAESEVGNSSPGEKGSDAPSTEARGMELEGKEEEGEAMVEDEEEAKIPKAAQPKSESKENAEDNESGSTDSGQENSGETRLLRSGTYSDRTESKAYGSVTHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECNKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHTGEAKYRCDDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCVHCQRQFADPGALQRHVRIHTGEKPCQCLICGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCTVCNKAFVNVGDLSKHIIIHTGEKPFLCDKCGRGFNRVDNLRSHVKTVHQGKAGMKILEPEDGSELNIVTVASDDMVTLATEALAATAVTQLTVVPVAAAVTADETEALKAEITKAVKQVQEAGEEGRGPASRSPGPRPAAATPRASPLPLQTPTLRSFTPAIPAGRNSWMPPAWRSTSASTQPRRSSCSRPTRTFTSSTGPPLPPGRPSRSSLPPSCSSAPVTAPKRPPPPPWPLCPLLGRARRLLSDPPAPPRLYLKSAAWKRCKKCISGRRERRNKLQYFLKRVVESTASQRSA", "length": 895, "header": "tr|A0A8V0Z3G0-1|A0A8V0Z3G0_CHICK Isoform 1 of Zinc finger and BTB domain-containing protein 17 OS=Gallus gallus OX=9031 GN=ZBTB17 PE=3 SV=1 CANONICAL=A0A8V0Z3G0-1" }, "locus": { "chromosome": "21", "start_pos": 4302913, "end_pos": 4298883, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039946.1", "url": "https://www.ensembl.org/id/ENSGALT00010039946.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023131.1", "url": "https://www.ensembl.org/id/ENSGALP00010023131.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 148, "start_aa": "Thr", "end_pos": 148, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr148", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:396541", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:396541", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F7FQA4-1", "protein_name": "Zinc finger and BTB domain-containing protein 17", "gene_name": "Zbtb17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFPQHSQRVLEQLNQQRQMGLLCDCTFVVDGVDFKAHKAVLAACSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLHLSPENVDDVLAVASFLQMQDIITACHTLKSLAEPTSTTGESADASAEEGGDKRAKEEKAAATVLSRLDQARSSSSAGPGRELKEEWGGQAESASRGFVPAMEETHLTSAQSPNPASHPSSGAEQTEKADAPREPPPVELKPDPTSSMAAAEAEALSESSEQEMEVEPASKGEEGQEEEGPGPATVKEEGVHLENGEPPEENEESAGTDSGHELGMEGQNLRSGTYGDRTESKAYGSIIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCGDCGKLFTTSGNLKRHQLVHSGQKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCTHCQRQFADPGALQRHVRIHTGEKPCQCVICGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGGEVSVVTVDDMVTLATEALAATAVTQLTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGGAWPAGQMLQAGELVFRPRDGTEGQPTLAETPPTAPDCLPPAE", "length": 819 }, "evidence": [ { "id": "A0A8V0Z3G0", "url": "https://omabrowser.org/oma/group/A0A8V0Z3G0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13105-1", "protein_name": "Zinc finger and BTB domain-containing protein 17", "gene_name": "ZBTB17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITACHALKSLAEPATSPGGNAEALATEGGDKRAKEEKVATSTLSRLEQAGRSTPIGPSRDLKEERGGQAQSAASGAEQTEKADAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEEQKEQEEQEEEGAGPAEVKEEGSQLENGEAPEENENEESAGTDSGQELGSEARGLRSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGSEVSVVTVDDMVTLATEALAATAVTQLTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGGTWPAGQVLQAGELVFRPRDGAEGQPALAETSPTAPECPPPAE", "length": 803 }, "evidence": [ { "id": "A0A8V0Z3G0", "url": "https://omabrowser.org/oma/group/A0A8V0Z3G0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60821-1", "protein_name": "Zinc finger and BTB domain-containing protein 17", "gene_name": "Zbtb17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFPQHSQRVLEQLNQQRQLGLLCDCTFVVDGVDFKAHKAVLAACSEYFKMLFVDQKDVVHLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVASFLQMQDIVTACHTLKSLAEPSSTTGESADASAVEGGDKRAKDEKAAATMLSRLDQARGSSSTGPGRELKEERGGQAESASSGAEQTEKADAPREPPPVELKPDPTSSMAAAEAEALSESSEQEMEVEPASKGEDGQEEEGAGPATVKEEGMHLDNGEPPEENEESAGTDSGQELGMEGQNLRSGTYGDRTESKAYGSIIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCGDCGKLFTTSGNLKRHQLVHSGQKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCTHCQRQFADPGALQRHVRIHTGEKPCQCVICGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGGEVSVVTVDDMVTLATEALAATAVTQLTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACDSCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGSTWPAGQMLQAGELVFRPRDGTEGQPTLAESPPTAPDCLPPAE", "length": 794 }, "evidence": [ { "id": "A0A8V0Z3G0", "url": "https://omabrowser.org/oma/group/A0A8V0Z3G0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" }, { "name": "transcription coactivator binding", "id": "GO:0001223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001223", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor binding", "id": "GO:0140297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140297", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" }, { "name": "protein-DNA complex", "id": "GO:0032993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" }, { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 87, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 343, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 148 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 223, "end_pos": 225 }, { "start_pos": 279, "end_pos": 281 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3B8-1", "uniprot_ac": "A0A8V0Z3B8", "uniprot_id": "A0A8V0Z3B8_CHICK", "mass": { "chemical_mass": 101541.0, "monoisotopic_mass": 101541.0 }, "refseq": {}, "gene_names": [ { "name": "CLMN", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8" } ] } ], "protein_names": [ { "name": "Calmin", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8/entry#names_and_taxonomy" } ] }, { "name": "Calponin-like transmembrane domain protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLMN", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8", "locus": { "chromosome": "5", "start_pos": 45411856, "end_pos": 45480534, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017569", "url": "https://www.ensembl.org/id/ENSGALG00010017569" } ] } } ], "crossref": [ { "id": "A0A8V0Z3B8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3B8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21245", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21245", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100858625", "url": "https://www.ncbi.nlm.nih.gov/gene/100858625", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:100858625", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858625", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THEITIF", "url": "https://omabrowser.org/oma/group/THEITIF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1M6", "url": "https://www.orthodb.org/?gene=A0A8V0Z1M6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z224", "url": "https://www.orthodb.org/?gene=A0A8V0Z224", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3B4", "url": "https://www.orthodb.org/?gene=A0A8V0Z3B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3B8", "url": "https://www.orthodb.org/?gene=A0A8V0Z3B8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47535", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47535", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47535:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47535:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z1M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1M6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z224", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z224", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z224-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z224-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSEQSINEIAILNFLLPSSITSLPPTLAVGILLFQHNALDLRADQPYVERENVQKRTFTRWINLHLGKCKPPLKVRDLFMDIQDGKILMALLEVLSGQKLMHEYKSSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFFQIKELTGNLNRNSSSSSLSSGPSGPESDTSYPSTPNIERSMSVTVKDQRKAIRALLFWVQRKTRKYGVAVQDFTSSWRSGLAFLAIIKAIDSTLVDMKHALEKSARENLEDAFSIAQNKLGVPRLLEPEDIMVESPDEQSIVTYVAQFLEHFPELEGEDFTDPEKELPIESTYVHIKDTPSEKESKILILRESDKNMYTVNHERSHPAPPKVHIHDTPERILSETVPEACNGKLSQVLGDSQEISEDEPQRPTSLKITGSASYESSSSWEVLSDKLMPGDGGISDDPLKQSDDLSPAVLTDQKNSVDSFEDYSEELTKETYTEYDNETKSLSANTSSLSPLSWTSGILTDESINKVEESNSQNSIILPEVTSKQEDTHKYVLHLLNEEVLKLPENEHAKQSPVLETTENNHCSLNGSNLKSQEMSTLLETSDDSLSDVPNNGEDSDSCDDDESSAEVLLSSSKVSVIPHDLFYYPHYNVPISAVLDAYVEPCLKRYDTENDISFSETVTDSLHEEGAPAQDYKEDAPEPGLQNNHGVPSLEMGTENGEEETIDMNSHSTSFYEKEVPLLIGEIEIEIDSQKATGNEDSMILQHPEVIGDNLDDFAIVGVRLEESSNGDEKKENMIKVEELQTSEVGHTALFDDELEEIANSQELTRTCDNDSNIYLRKRFPDTAGLETSGKKDQKMTEVDENLLIIGMKKDMETKETAAPPRQTPSVEQSELFYLIIFLWVLVYCLLVLPQLFSFKV", "length": 907, "header": "tr|A0A8V0Z3B8-1|A0A8V0Z3B8_CHICK Isoform 1 of Calmin OS=Gallus gallus OX=9031 GN=CLMN PE=1 SV=1 CANONICAL=A0A8V0Z3B8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8/entry#A0A8V0Z1M6-1", "sequence": { "sequence": "MAGQEWDWFQREELIGHISDIRVQNLQVERENVQKRTFTRWINLHLGKCKPPLKVRDLFMDIQDGKILMALLEVLSGQKLMHEYKSSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFFQIKELTGNLNRNSSSSSLSSGPSGPESDTSYPSTPNIERSMSVTVKDQRKAIRALLFWVQRKTRKYGVAVQDFTSSWRSGLAFLAIIKAIDSTLVDMKHALEKSARENLEDAFSIAQNKLGVPRLLEPEDIMVESPDEQSIVTYVAQFLEHFPELEGEDFTDPEKELPIESTYVHIKDTPSEKESKILILRESDKNMYTVNHERSHPAPPKVHIHDTPERILSETVPEACNGKLSQVLGDSQEISEDEPQRPTSLKITGSASYESSSSWEVLSDKLMPGDGGISDDPLKQSDDLSPAVLTDQKNSVDSFEDYSEELTKETYTEYDNETKSLSANTSSLSPLSWTSGILTDESINKVEESNSQNSIILPEVTSKQEDTHKYVLHLLNEEVLKLPENEHAKQSPVLETTENNHCSLNGSNLKSQEMSTLLETSDDSLSDVPNNGEDSDSCDDDESSAEVLLSSSKVSVIPHDLFYYPHYNVPISAVLDAYVEPCLKRYDTENDISFSETVTDSLHEEGAPAQDYKEDAPEPGLQNNHGVPSLEMGTENGEEETIDMNSHSTSFYEKEVPLLIGEIEIEIDSQKATGNEDSMILQHPEVIGDNLDDFAIVGVRLEESSNGDEKKENMIKVEELQTSEVGHTALFDDELEEIANSQELTRTCDNDSNIYLRKRFPDTAGLETSGKKDQKMTEVDENLLIIGMKKDMETKETAAPPRQTPSVEQSELFYLIIFLWVLVYCLLVLPQLFSFKV", "length": 885, "header": "tr|A0A8V0Z1M6-1|A0A8V0Z3B8_CHICK Computationally mapped isoform of Calmin OS=Gallus gallus OX=9031 GN=CLMN PE=1 SV=1 CANONICAL=A0A8V0Z3B8-1" }, "locus": { "chromosome": "5", "start_pos": 45480440, "end_pos": 45413753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042475.1", "url": "https://www.ensembl.org/id/ENSGALT00010042475.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024965.1", "url": "https://www.ensembl.org/id/ENSGALP00010024965.1" } ] } }, { "isoform_ac": "A0A8V0Z224-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8/entry#A0A8V0Z224-1", "sequence": { "sequence": "MTRGASEQTWVCVSAWRGSLGVEVLKGEKPKKDVTRLMVYCILRFVVERENVQKRTFTRWINLHLGKCKPPLKVRDLFMDIQDGKILMALLEVLSGQKLMHEYKSSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFFQIKELTGNLNRNSSSSSLSSGPSGPESDTSYPSTPNIERSMSVTVKDQRKAIRALLFWVQRKTRKYGVAVQDFTSSWRSGLAFLAIIKAIDSTLVDMKHALEKSARENLEDAFSIAQNKLGVPRLLEPEDIMVESPDEQSIVTYVAQFLEHFPELEGEDFTDPEKELPIESTYVHIKDTPSEKESKILILRESDKNMYTVNHERSHPAPPKVHIHDTPERILSETVPEACNGKLSQVLGDSQEISEDEPQRPTSLKITGSASYESSSSWEVLSDKLMPGDGGISDDPLKQSDDLSPAVLTDQKNSVDSFEDYSEELTKETYTEYDNETKSLSANTSSLSPLSWTSGILTDESINKVEESNSQNSIILPEVTSKQEDTHKYVLHLLNEEVLKLPENEHAKQSPVLETTENNHCSLNGSNLKSQEMSTLLETSDDSLSDVPNNGEDSDSCDDDESSAEVLLSSSKVSVIPHDLFYYPHYNVPISAVLDAYVEPCLKRYDTENDISFSETVTDSLHEEGAPAQDYKEDAPEPGLQNNHGVPSLEMGTENGEEETIDMNSHSTSFYEKEVPLLIGEIEIEIDSQKATGNEDSMILQHPEVIGDNLDDFAIVGVRLEESSNGDEKKENMIKVEELQTSEVGHTALFDDELEEIANSQELTRTCDNDSNIYLRKRFPDTAGLETSGKKDQKMTEVDENLLIIGMKKDMETKETAAPPRQTPSVEQSELFYLIIFLWVLVYCLLVLPQLFSFKV", "length": 904, "header": "tr|A0A8V0Z224-1|A0A8V0Z3B8_CHICK Computationally mapped isoform of Calmin OS=Gallus gallus OX=9031 GN=CLMN PE=1 SV=1 CANONICAL=A0A8V0Z3B8-1" }, "locus": { "chromosome": "5", "start_pos": 45434037, "end_pos": 45413753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042467.1", "url": "https://www.ensembl.org/id/ENSGALT00010042467.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024957.1", "url": "https://www.ensembl.org/id/ENSGALP00010024957.1" } ] } }, { "isoform_ac": "A0A8V0Z3B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8/entry#A0A8V0Z3B4-1", "sequence": { "sequence": "MRCGISPFLITVTWCKPPLKVRDLFMDIQDGKILMALLEVLSGQKLMHEYKSSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFFQIKELTGNLNRNSSSSSLSSGPSGPESDTSYPSTPNIERSMSVTVKDQRKAIRALLFWVQRKTRKYGVAVQDFTSSWRSGLAFLAIIKAIDSTLVDMKHALEKSARENLEDAFSIAQNKLGVPRLLEPEDIMVESPDEQSIVTYVAQFLEHFPELEGEDFTDPEKELPIESTYVHIKDTPSEKESKILILRESDKNMYTVNHERSHPAPPKVHIHDTPERILSETVPEACNGKLSQVLGDSQEISEDEPQRPTSLKITGSASYESSSSWEVLSDKLMPGDGGISDDPLKQSDDLSPAVLTDQKNSVDSFEDYSEELTKETYTEYDNETKSLSANTSSLSPLSWTSGILTDESINKVEESNSQNSIILPEVTSKQEDTHKYVLHLLNEEVLKLPENEHAKQSPVLETTENNHCSLNGSNLKSQEMSTLLETSDDSLSDVPNNGEDSDSCDDDESSAEVLLSSSKVSVIPHDLFYYPHYNVPISAVLDAYVEPCLKRYDTENDISFSETVTDSLHEEGAPAQDYKEDAPEPGLQNNHGVPSLEMGTENGEEETIDMNSHSTSFYEKEVPLLIGEIEIEIDSQKATGNEDSMILQHPEVIGDNLDDFAIVGVRLEESSNGDEKKENMIKVEELQTSEVGHTALFDDELEEIANSQELTRTCDNDSNIYLRKRFPDTAGLETSGKKDQKMTEVDENLLIIGMKKDMETKETAAPPRQTPSVEQSELFYLIIFLWVLVYCLLVLPQLFSFKV", "length": 851, "header": "tr|A0A8V0Z3B4-1|A0A8V0Z3B4_CHICK Computationally mapped isoform of Calmin OS=Gallus gallus OX=9031 GN=CLMN PE=1 SV=1 CANONICAL=A0A8V0Z3B8-1" }, "locus": { "chromosome": "5", "start_pos": 45430222, "end_pos": 45413753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042466.1", "url": "https://www.ensembl.org/id/ENSGALT00010042466.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024956.1", "url": "https://www.ensembl.org/id/ENSGALP00010024956.1" } ] } }, { "isoform_ac": "A0A8V0Z3B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8/entry#A0A8V0Z3B8-1", "sequence": { "sequence": "MSRSEQSINEIAILNFLLPSSITSLPPTLAVGILLFQHNALDLRADQPYVERENVQKRTFTRWINLHLGKCKPPLKVRDLFMDIQDGKILMALLEVLSGQKLMHEYKSSTHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNSSLVLGLIWNIILFFQIKELTGNLNRNSSSSSLSSGPSGPESDTSYPSTPNIERSMSVTVKDQRKAIRALLFWVQRKTRKYGVAVQDFTSSWRSGLAFLAIIKAIDSTLVDMKHALEKSARENLEDAFSIAQNKLGVPRLLEPEDIMVESPDEQSIVTYVAQFLEHFPELEGEDFTDPEKELPIESTYVHIKDTPSEKESKILILRESDKNMYTVNHERSHPAPPKVHIHDTPERILSETVPEACNGKLSQVLGDSQEISEDEPQRPTSLKITGSASYESSSSWEVLSDKLMPGDGGISDDPLKQSDDLSPAVLTDQKNSVDSFEDYSEELTKETYTEYDNETKSLSANTSSLSPLSWTSGILTDESINKVEESNSQNSIILPEVTSKQEDTHKYVLHLLNEEVLKLPENEHAKQSPVLETTENNHCSLNGSNLKSQEMSTLLETSDDSLSDVPNNGEDSDSCDDDESSAEVLLSSSKVSVIPHDLFYYPHYNVPISAVLDAYVEPCLKRYDTENDISFSETVTDSLHEEGAPAQDYKEDAPEPGLQNNHGVPSLEMGTENGEEETIDMNSHSTSFYEKEVPLLIGEIEIEIDSQKATGNEDSMILQHPEVIGDNLDDFAIVGVRLEESSNGDEKKENMIKVEELQTSEVGHTALFDDELEEIANSQELTRTCDNDSNIYLRKRFPDTAGLETSGKKDQKMTEVDENLLIIGMKKDMETKETAAPPRQTPSVEQSELFYLIIFLWVLVYCLLVLPQLFSFKV", "length": 907, "header": "tr|A0A8V0Z3B8-1|A0A8V0Z3B8_CHICK Isoform 1 of Calmin OS=Gallus gallus OX=9031 GN=CLMN PE=1 SV=1 CANONICAL=A0A8V0Z3B8-1" }, "locus": { "chromosome": "5", "start_pos": 45435314, "end_pos": 45413753, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042471.1", "url": "https://www.ensembl.org/id/ENSGALT00010042471.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024961.1", "url": "https://www.ensembl.org/id/ENSGALP00010024961.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100858625", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100858625", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B8" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 161, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 575, "end_pos": 577 }, { "start_pos": 820, "end_pos": 822 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3H1-1", "uniprot_ac": "A0A8V0Z3H1", "uniprot_id": "A0A8V0Z3H1_CHICK", "mass": { "chemical_mass": 85087.0, "monoisotopic_mass": 85087.0 }, "refseq": { "ac": "XP_015133576", "name": "centrosomal protein of 68 kDa isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133576" }, "gene_names": [ { "name": "CEP68", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H1" } ] }, { "name": "CEP68", "type": "synonym", "evidence": [ { "id": "XP_015133576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133576" } ] } ], "protein_names": [ { "name": "Centrosomal protein 68", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H1/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 68 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015133576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133576" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015133576.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015133576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133576" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CEP68", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H1", "locus": { "chromosome": "3", "start_pos": 10149136, "end_pos": 10142231, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017594", "url": "https://www.ensembl.org/id/ENSGALG00010017594" } ] } } ], "crossref": [ { "id": "A0A8V0Z3H1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3H1", "database": "AlphaFoldDB", "categories": [] }, { "id": "421274", "url": "https://www.ncbi.nlm.nih.gov/gene/421274", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421274", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421274", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HAEHLYE", "url": "https://omabrowser.org/oma/group/HAEHLYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z1S9", "url": "https://www.orthodb.org/?gene=A0A8V0Z1S9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z285", "url": "https://www.orthodb.org/?gene=A0A8V0Z285", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3H1", "url": "https://www.orthodb.org/?gene=A0A8V0Z3H1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14514", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14514", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14514:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14514:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_015133576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015133576", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1S9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z1S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z285", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z285", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z285-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z285-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3H1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVGAERAARPVRPRFLGAKPRSATRRLEEEGKVERCSRERRAQSAAALHRRRSSMLMALDVAKSLSEASLSQKAKCYGRWDCVDGQTDCPELASNVHQLLGAEEAKTTLNSTESLAASGCDGLATGVTAPTPRLPGMKANCLERRPLIYGGDSSRCLGHWAFLGQQQNSTEESGAASVRHVASRHWSQAPWSPSSSPPESLPQQTLPSPKSPLQSRSRSSFSTLSLEENSVSEQQEGRRSQSSPASLDTPSAATWELCHQPGVTGGRTGGGRTGGGRTLRARKALSPLLRDCAAVERVRKMSSYQADYWACAIPDSLPPSPDRQSPHWNPNKEYEDLLDYTYPLKPKYKLGKDPEPLFHDSGVDLDSFSLSPEGTFRSTSIYGVGWQDRGRRENQHRGAVASARRYSTPVAGKGGDAGAVSHCEPSPIAKASLAKSASSAGTARPAAGFARGLMLAGLSSFGCPDVDGGSWGTGNPFSSHGGKVRSAERFLPTTRVLPLRREWDGDEEFLSLPPRLRELETLSQILSDLSLTIRTPRQSHWDPSPHSHGPENLSSERAPFGGVGSRDQRERTGGSAGLCHPYGWDSAQPSSRINRDPLHRLHLPASSGAVLEGTRLSRLHAAGCPTERGQWSESLAQCVKVFCHQLEELICWLYDVADTADSWVPPMPDAASVRAALHRYLEFRKDVADHQSLTESVLQRGAALLECMASNSPALKDTLGLIERQSEELENHAERLYQSVLAAVGPVQGEGSSSAQQAAAQAPEAQWVSRVLPPSELSFVSQAQEG", "length": 787, "header": "tr|A0A8V0Z3H1-1|A0A8V0Z3H1_CHICK Isoform 1 of Centrosomal protein 68 OS=Gallus gallus OX=9031 GN=CEP68 PE=4 SV=1 CANONICAL=A0A8V0Z3H1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z1S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H1/entry#A0A8V0Z1S9-1", "sequence": { "sequence": "MLMALDVAKSLSEASLSQKAKCYGRWDCVDGQTDCPELASNVHQLLGAEEAKTTLNSTESLAASGCDGLATGVTAPTPRLPGMKANCLERRPLIYGGDSSRCLGHWAFLGQQQNSTEESGAASVRHVASRHWSQAPWSPSSSPPESLPQQTLPSPKSPLQSRSRSSFSTLSLEENSVSEQQEGRRSQSSPASLDTPSAATWELCHQPGVTGGRTGGGRTGGGRTLRARKALSPLLRDCAAVERVRKMSSYQADYWACAIPDSLPPSPDRQSPHWNPNKEYEDLLDYTYPLKPKYKLGKDPEPLFHDSGVDLDSFSLSPEGTFRSTSIYGVGWQDRGRRENQHRGAVASARRYSTPVAGKGGDAGAVSHCEPSPIAKASLAKSASSAGTARPAAGFARGLMLAGLSSFGCPDVDGGSWGTGNPFSSHGGKVRSAERFLPTTRVLPLRREWDGDEEFLSLPPRLRELETLSQILSDLSLTIRTPRQSHWDPSPHSHGPENLSSERAPFGGVGSRDQRERTGGSAGLCHPYGWDSAQPSSRINRDPLHRLHLPASSGAVLEGTRLSRLHAAGCPTERGQWSESLAQCVKVFCHQLEELICWLYDVADTADSWVPPMPDAASVRAALHRYLEFRKDVADHQSLTESVLQRGAALLECMASNSPALKDTLGLIERQSEELENHAERLYQSVLAAVGPVQGEGSSSAQQAAAQAPEAQWVSRVRGGETAARSCG", "length": 728, "header": "tr|A0A8V0Z1S9-1|A0A8V0Z3H1_CHICK Computationally mapped isoform of Centrosomal protein 68 OS=Gallus gallus OX=9031 GN=CEP68 PE=4 SV=1 CANONICAL=A0A8V0Z3H1-1" }, "locus": { "chromosome": "3", "start_pos": 10148132, "end_pos": 10143539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042535.1", "url": "https://www.ensembl.org/id/ENSGALT00010042535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025025.1", "url": "https://www.ensembl.org/id/ENSGALP00010025025.1" } ] } }, { "isoform_ac": "A0A8V0Z285-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H1/entry#A0A8V0Z285-1", "sequence": { "sequence": "MLMALDVAKSLSEASLSQKAKCYGRWDCVDGQTDCPELASNVHQLLGAEEAKTTLNSTESLAASGCDGLATGVTAPTPRLPGMKANCLERRPLIYGGDSSRCLGHWAFLGQQQNSTEESGAASVRHVASRHWSQAPWSPSSSPPESLPQQTLPSPKSPLQSRSRSSFSTLSLEENSVSEQQEGRRSQSSPASLDTPSAATWELCHQPGVTGGRTGGGRTGGGRTLRARKALSPLLRDCAAVERVRKMSSYQADYWACAIPDSLPPSPDRQSPHWNPNKEYEDLLDYTYPLKPKYKLGKDPEPLFHDSGVDLDSFSLSPEGTFRSTSIYGVGWQDRGRRENQHRGAVASARRYSTPVAGKGGDAGAVSHCEPSPIAKASLAKSASSAGTARPAAGFARGLMLAGLSSFGCPDVDGGSWGTGNPFSSHGGKVRSAERFLPTTRVLPLRREWDGDEEFLSLPPRLRELETLSQILSDLSLTIRTPRQSHWDPSPHSHGPENLSSERAPFGGVGSRDQRERTGGSAGLCHPYGWDSAQPSSRINRDPLHRLHLPASSGAVLEGTRLSRLHAAGCPTERGQWSESLAQCVKVFCHQLEELICWLYDVADTADSWVPPMPDAASVRAALHRYLEFRKDVADHQSLTESVLQRGAALLECMASNSPALKDTLGLIERQSEELENHAERLYQSVLAAVGPVQGEGSSSAQQAAAQAPEAQWVSRVLPPSELSFVSQAQEG", "length": 732, "header": "tr|A0A8V0Z285-1|A0A8V0Z3H1_CHICK Computationally mapped isoform of Centrosomal protein 68 OS=Gallus gallus OX=9031 GN=CEP68 PE=4 SV=1 CANONICAL=A0A8V0Z3H1-1" }, "locus": { "chromosome": "3", "start_pos": 10148581, "end_pos": 10143539, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042532.1", "url": "https://www.ensembl.org/id/ENSGALT00010042532.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025022.1", "url": "https://www.ensembl.org/id/ENSGALP00010025022.1" } ] } }, { "isoform_ac": "A0A8V0Z3H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H1/entry#A0A8V0Z3H1-1", "sequence": { "sequence": "MVVGAERAARPVRPRFLGAKPRSATRRLEEEGKVERCSRERRAQSAAALHRRRSSMLMALDVAKSLSEASLSQKAKCYGRWDCVDGQTDCPELASNVHQLLGAEEAKTTLNSTESLAASGCDGLATGVTAPTPRLPGMKANCLERRPLIYGGDSSRCLGHWAFLGQQQNSTEESGAASVRHVASRHWSQAPWSPSSSPPESLPQQTLPSPKSPLQSRSRSSFSTLSLEENSVSEQQEGRRSQSSPASLDTPSAATWELCHQPGVTGGRTGGGRTGGGRTLRARKALSPLLRDCAAVERVRKMSSYQADYWACAIPDSLPPSPDRQSPHWNPNKEYEDLLDYTYPLKPKYKLGKDPEPLFHDSGVDLDSFSLSPEGTFRSTSIYGVGWQDRGRRENQHRGAVASARRYSTPVAGKGGDAGAVSHCEPSPIAKASLAKSASSAGTARPAAGFARGLMLAGLSSFGCPDVDGGSWGTGNPFSSHGGKVRSAERFLPTTRVLPLRREWDGDEEFLSLPPRLRELETLSQILSDLSLTIRTPRQSHWDPSPHSHGPENLSSERAPFGGVGSRDQRERTGGSAGLCHPYGWDSAQPSSRINRDPLHRLHLPASSGAVLEGTRLSRLHAAGCPTERGQWSESLAQCVKVFCHQLEELICWLYDVADTADSWVPPMPDAASVRAALHRYLEFRKDVADHQSLTESVLQRGAALLECMASNSPALKDTLGLIERQSEELENHAERLYQSVLAAVGPVQGEGSSSAQQAAAQAPEAQWVSRVLPPSELSFVSQAQEG", "length": 787, "header": "tr|A0A8V0Z3H1-1|A0A8V0Z3H1_CHICK Isoform 1 of Centrosomal protein 68 OS=Gallus gallus OX=9031 GN=CEP68 PE=4 SV=1 CANONICAL=A0A8V0Z3H1-1" }, "locus": { "chromosome": "3", "start_pos": 10148581, "end_pos": 10142486, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042531.1", "url": "https://www.ensembl.org/id/ENSGALT00010042531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025021.1", "url": "https://www.ensembl.org/id/ENSGALP00010025021.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421274", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421274", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 553, "end_pos": 555 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3T2-1", "uniprot_ac": "A0A8V0Z3T2", "uniprot_id": "A0A8V0Z3T2_CHICK", "mass": { "chemical_mass": 55477.0, "monoisotopic_mass": 55477.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Syncoilin, intermediate filament protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z3T2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3T2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR027702", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027702", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z239", "url": "https://www.orthodb.org/?gene=A0A8V0Z239", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3T2", "url": "https://www.orthodb.org/?gene=A0A8V0Z3T2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9L3", "url": "https://www.orthodb.org/?gene=A0A8V0Z9L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47147:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47147:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z239", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z239", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z239-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z239-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9L3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGTLLGKETARAEAPLGVDGAETPLDSEADEQILLDVDAGGTGILLDVDGAGIPLDVEDEVGIPLDVDAGGTGALLDADGAGLPLDVEAEGLGILLDMDAAVAGLLQDMDASGIPLHVDGAEIPLDAVRAGIPLAMDTDGAGIPPGAAGVGVPQDMDAEGAGTPQAPEGTERPCLSLEELGEYFQECIEAVEQLEKERDALIEELTQLREPALQDIRHAHQEIQAACRLLAKVELERDNLRDEIRQIKQKLFKVTKECVACQHAAYRDELESQAGRLTGELSRLRESCEKEKEALRQRLEAPPCRQDPQYLQESRRLSAEFESLVTRSRRGLEEHYEPQLLRLLERREAGTRALQELQGEVQGMKEALRPLQGEVSRLRLQNRSLEEQIVLVKQKRDEEVGQYREQVEELEDRLKELKNSVQLQQRKNQELEELRSSLHHELSIYKSVSAPCTPSCPGSGCSVVQWKLRIPFSPSPLKPPPITALWEGIPHPSSCSSSLHETPQQ", "length": 506, "header": "tr|A0A8V0Z3T2-1|A0A8V0Z3T2_CHICK Isoform 1 of Syncoilin, intermediate filament protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0Z3T2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z239-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2/entry#A0A8V0Z239-1", "sequence": { "sequence": "MPGTLLGKETARAEAPLGVDGAETPLDSEADEQILLDVDAGGTGILLDVDGAGIPLDVEDEVGIPLDVDAGGTGALLDADGAGLPLDVEAEGLGILLDMDAAVAGLLQDMDASGIPLHVDGAEIPLDAVRAGIPLAMDTDGAGIPPGAAGVGVPQDMDAEGAGTPQAPEGTERPCLSLEELGEYFQECIEAVEQLEKERDALIEELTQLREPALQDIRHAHQEIQAACRLLAKVELERDNLRDEIRQIKQKLFKVTKECVACQHAAYRDELESQAGRLTGELSRLRESCEKEKEALRQRLEAPPCRQDPQYLQESRRLSAEFESLVTRSRRGLEEHYEPQLLRLLERREAGTRALQELQGEVQGMKEALRPLQGEVSRLRLQNRSLEEQIVLVKQKRDEEVGQYREQVEELEDRLKELKNSVQLQQRKNQELEELRSSLHHELSIYKSVSAPNGGRESGSQCEKHCCRSFSDGTAFCFSICAAAFTQGFSTPF", "length": 493, "header": "tr|A0A8V0Z239-1|A0A8V0Z3T2_CHICK Computationally mapped isoform of Syncoilin, intermediate filament protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0Z3T2-1" }, "locus": { "chromosome": "23", "start_pos": 5602535, "end_pos": 5599898, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042652.1", "url": "https://www.ensembl.org/id/ENSGALT00010042652.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025142.1", "url": "https://www.ensembl.org/id/ENSGALP00010025142.1" } ] } }, { "isoform_ac": "A0A8V0Z3T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2/entry#A0A8V0Z3T2-1", "sequence": { "sequence": "MPGTLLGKETARAEAPLGVDGAETPLDSEADEQILLDVDAGGTGILLDVDGAGIPLDVEDEVGIPLDVDAGGTGALLDADGAGLPLDVEAEGLGILLDMDAAVAGLLQDMDASGIPLHVDGAEIPLDAVRAGIPLAMDTDGAGIPPGAAGVGVPQDMDAEGAGTPQAPEGTERPCLSLEELGEYFQECIEAVEQLEKERDALIEELTQLREPALQDIRHAHQEIQAACRLLAKVELERDNLRDEIRQIKQKLFKVTKECVACQHAAYRDELESQAGRLTGELSRLRESCEKEKEALRQRLEAPPCRQDPQYLQESRRLSAEFESLVTRSRRGLEEHYEPQLLRLLERREAGTRALQELQGEVQGMKEALRPLQGEVSRLRLQNRSLEEQIVLVKQKRDEEVGQYREQVEELEDRLKELKNSVQLQQRKNQELEELRSSLHHELSIYKSVSAPCTPSCPGSGCSVVQWKLRIPFSPSPLKPPPITALWEGIPHPSSCSSSLHETPQQ", "length": 506, "header": "tr|A0A8V0Z3T2-1|A0A8V0Z3T2_CHICK Isoform 1 of Syncoilin, intermediate filament protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0Z3T2-1" }, "locus": { "chromosome": "23", "start_pos": 5602535, "end_pos": 5599663, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042658.1", "url": "https://www.ensembl.org/id/ENSGALT00010042658.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025148.1", "url": "https://www.ensembl.org/id/ENSGALP00010025148.1" } ] } }, { "isoform_ac": "A0A8V0Z9L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2/entry#A0A8V0Z9L3-1", "sequence": { "sequence": "MPGTLLGKETARAEAPLGVDGAETPLDSEADEQILLDVDAGGTGILLDVDGAGIPLDVEDEVGIPLDVDAGGTGALLDADGAGLPLDVEAEGLGILLDMDAAVAGLLQDMDASGIPLHVDGAEIPLDAVRAGIPLAMDTDGAGIPPGAAGVGVPQDMDAEGAGTPQAPEGTERPCLSLEELGEYFQECIEAVEQLEKERDALIEELTQLREPALQDIRHAHQEIQAACRLLAKVELERDNLRDEIRQIKQKLFKVTKECVACQHAAYRDELESQAGRLTGELSRLRESCEKEKEALRQRLEAPPCRQDPQYLQESRRLSAEFESLVTRSRRGLEEHYEPQLLRLLERREAGTRALQELQGEVQGMKEALRPLQGEVSRLRLQNRSLEEQIVLVKQKRDEEVGQYREQVEELEDRLKELKNSVQLQQRKNQELEELRSSLHHELSIYKGCLEIYGHLCKSEEKPDQEC", "length": 467, "header": "tr|A0A8V0Z9L3-1|A0A8V0Z3T2_CHICK Computationally mapped isoform of Syncoilin, intermediate filament protein OS=Gallus gallus OX=9031 GN= PE=1 SV=1 CANONICAL=A0A8V0Z3T2-1" }, "locus": { "chromosome": "23", "start_pos": 5602535, "end_pos": 5599059, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042661.1", "url": "https://www.ensembl.org/id/ENSGALT00010042661.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025151.1", "url": "https://www.ensembl.org/id/ENSGALP00010025151.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2" } ], "pmid": "" }, { "name": "neuromuscular junction", "id": "GO:0031594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031594", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2" } ], "pmid": "" }, { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3T2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3T2" }, { "id": "SM01391", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01391" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 169, "end_pos": 450, "start_aa": "Glu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 383, "end_pos": 385 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z469-1", "uniprot_ac": "A0A8V0Z469", "uniprot_id": "A0A8V0Z469_CHICK", "mass": { "chemical_mass": 58171.0, "monoisotopic_mass": 58171.0 }, "refseq": { "ac": "XP_025005238", "name": "fibroblast growth factor receptor-like 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005238" }, "gene_names": [ { "name": "FGFRL1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ] }, { "name": "FGFRL1", "type": "synonym", "evidence": [ { "id": "XP_025005238", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005238" } ] } ], "protein_names": [ { "name": "Fibroblast growth factor receptor-like 1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469/entry#names_and_taxonomy" } ] }, { "name": "fibroblast growth factor receptor-like 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025005238", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005238" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025005238.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025005238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005238" } ] }, { "annotation": "Has a negative effect on cell proliferation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2J4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2J4#function" }, { "database": "UniProtKB", "id": "ARBA00053149", "url": "https://www.uniprot.org/uniprotkb/ARBA00053149#function" }, { "database": "UniProtKB", "id": "A0A8V0ZA07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA07#function" }, { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FGFRL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469", "locus": { "chromosome": "4", "start_pos": 84572137, "end_pos": 84739857, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017706", "url": "https://www.ensembl.org/id/ENSGALG00010017706" } ] } } ], "crossref": [ { "id": "A0A8V0Z469", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z469", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05856", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05856", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "395107", "url": "https://www.ncbi.nlm.nih.gov/gene/395107", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LIHANNM", "url": "https://omabrowser.org/oma/group/LIHANNM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2J4", "url": "https://www.orthodb.org/?gene=A0A8V0Z2J4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z469", "url": "https://www.orthodb.org/?gene=A0A8V0Z469", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA07", "url": "https://www.orthodb.org/?gene=A0A8V0ZA07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19890", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19890", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19890:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19890:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5658623", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5658623", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_025005238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005238", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2J4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z469-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA07", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA07-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRVVHLGGTEEPQRELYEAPRTAARAAHRDLLFNMGLQLALLLAGIVALSDSARGPPRIVDKVIHRQSVRLGRTIKLLCPVEGDPPPLTMWMKDGRTIHSGWTRFRILQQGLKIKEVESEDAGTYICKATNGFGSTNVNYTLIVIDDTSSGKNSQTPEGSNGEYEDHSGKQWAQPRFTQPAKMRRRVIARPVGSSIRLKCVASGNPRPDITWLKDNKPLMPHEIGENKKKKWTLNLKNLKPEDSGKYTCRVFNKVGEINATYKVEVIQRTRSKPILTGTHPVNTTVDYGGTTSFQCKVRSDVKPVIQWLKRVEYGTESKYNSTIDVGGQKFVVLPTGEVWSRPDGSYLNKLMITRAKEEDAGMYICLGANTMGYSFRSAFLTVLPDPKPPSAPVPPSSVSSLPWPVIIGIPAGAVFIFGTILLWLCQTKKKPCSPPAAAPVHRPQPRDRICVSQVPDKDCISSINYEEYVAQQQHLLSQGPALAPAMASKMYPKIYTDIHTHTHSHVEGKVHQHQHIQYQC", "length": 522, "header": "tr|A0A8V0Z469-1|A0A8V0Z469_CHICK Isoform 1 of Fibroblast growth factor receptor-like 1 OS=Gallus gallus OX=9031 GN=FGFRL1 PE=4 SV=1 CANONICAL=A0A8V0Z469-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469/entry#A0A8V0Z2J4-1", "sequence": { "sequence": "MNISSFGLQAVLTCQAVLCFGPPRIVDKVIHRQSVRLGRTIKLLCPVEGDPPPLTMWMKDGRTIHSGWTRFRILQQGLKIKEVESEDAGTYICKATNGFGSTNVNYTLIVIDDTSSGKNSQTPEGSNGEYEDHSGKQWAQPRFTQPAKMRRRVIARPVGSSIRLKCVASGNPRPDITWLKDNKPLMPHEIGENKKKKWTLNLKNLKPEDSGKYTCRVFNKVGEINATYKVEVIQRTRSKPILTGTHPVNTTVDYGGTTSFQCKVRSDVKPVIQWLKRVEYGTESKYNSTIDVGGQKFVVLPTGEVWSRPDGSYLNKLMITRAKEEDAGMYICLGANTMGYSFRSAFLTVLPDPKPPSAPVPPSSVSSLPWPVIIGIPAGAVFIFGTILLWLCQTKKKPCSPPAAAPVHRPQPRDRICVSQVPDKDCISSINYEEYVAQQQHLLSQGPALAPAMASKMYPKIYTDIHTHTHSHVEGKVHQHQHIQYQC", "length": 487, "header": "tr|A0A8V0Z2J4-1|A0A8V0Z469_CHICK Computationally mapped isoform of Fibroblast growth factor receptor-like 1 OS=Gallus gallus OX=9031 GN=FGFRL1 PE=4 SV=1 CANONICAL=A0A8V0Z469-1" }, "locus": { "chromosome": "4", "start_pos": 84661095, "end_pos": 84576140, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042808.1", "url": "https://www.ensembl.org/id/ENSGALT00010042808.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025298.1", "url": "https://www.ensembl.org/id/ENSGALP00010025298.1" } ] } }, { "isoform_ac": "A0A8V0Z469-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469/entry#A0A8V0Z469-1", "sequence": { "sequence": "MRRVVHLGGTEEPQRELYEAPRTAARAAHRDLLFNMGLQLALLLAGIVALSDSARGPPRIVDKVIHRQSVRLGRTIKLLCPVEGDPPPLTMWMKDGRTIHSGWTRFRILQQGLKIKEVESEDAGTYICKATNGFGSTNVNYTLIVIDDTSSGKNSQTPEGSNGEYEDHSGKQWAQPRFTQPAKMRRRVIARPVGSSIRLKCVASGNPRPDITWLKDNKPLMPHEIGENKKKKWTLNLKNLKPEDSGKYTCRVFNKVGEINATYKVEVIQRTRSKPILTGTHPVNTTVDYGGTTSFQCKVRSDVKPVIQWLKRVEYGTESKYNSTIDVGGQKFVVLPTGEVWSRPDGSYLNKLMITRAKEEDAGMYICLGANTMGYSFRSAFLTVLPDPKPPSAPVPPSSVSSLPWPVIIGIPAGAVFIFGTILLWLCQTKKKPCSPPAAAPVHRPQPRDRICVSQVPDKDCISSINYEEYVAQQQHLLSQGPALAPAMASKMYPKIYTDIHTHTHSHVEGKVHQHQHIQYQC", "length": 522, "header": "tr|A0A8V0Z469-1|A0A8V0Z469_CHICK Isoform 1 of Fibroblast growth factor receptor-like 1 OS=Gallus gallus OX=9031 GN=FGFRL1 PE=4 SV=1 CANONICAL=A0A8V0Z469-1" }, "locus": { "chromosome": "4", "start_pos": 84739272, "end_pos": 84576140, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042809.1", "url": "https://www.ensembl.org/id/ENSGALT00010042809.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025299.1", "url": "https://www.ensembl.org/id/ENSGALP00010025299.1" } ] } }, { "isoform_ac": "A0A8V0ZA07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469/entry#A0A8V0ZA07-1", "sequence": { "sequence": "MGLQLALLLAGIVALSDSARGPPRIVDKVIHRQSVRLGRTIKLLCPVEGDPPPLTMWMKDGRTIHSGWTRFRILQQGLKIKEVESEDAGTYICKATNGFGSTNVNYTLIVIDDTSSGKNSQTPEGSNGEYEDHSGKQWGKEQSQPRFTQPAKMRRRVIARPVGSSIRLKCVASGNPRPDITWLKDNKPLMPHEIGENKKKKWTLNLKNLKPEDSGKYTCRVFNKVGEINATYKVEVIQRTRSKPILTGTHPVNTTVDYGGTTSFQCKVRSDVKPVIQWLKRVEYGTESKYNSTIDVGGQKFVVLPTGEVWSRPDGSYLNKLMITRAKEEDAGMYICLGANTMGYSFRSAFLTVLPDPKPPSAPVPPSSVSSLPWPVIIGIPAGAVFIFGTILLWLCQTKKKPCSPPAAAPVHRPQPRDRICVSQVPDKDCISSINYEEYVAQQQHLLSQGPALAPAMASKMYPKIYTDIHTHTHSHVEGKVHQHQHIQYQC", "length": 491, "header": "tr|A0A8V0ZA07-1|A0A8V0Z469_CHICK Computationally mapped isoform of Fibroblast growth factor receptor-like 1 OS=Gallus gallus OX=9031 GN=FGFRL1 PE=4 SV=1 CANONICAL=A0A8V0Z469-1" }, "locus": { "chromosome": "4", "start_pos": 84738501, "end_pos": 84576140, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042812.1", "url": "https://www.ensembl.org/id/ENSGALT00010042812.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025302.1", "url": "https://www.ensembl.org/id/ENSGALP00010025302.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5658623", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5658623", "resource": "Reactome", "description": "FGFRL1 modulation of FGFR1 signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RM22-1", "protein_name": "Fibroblast growth factor receptor-like 1", "gene_name": "FGFRL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTPSPVLVLLLLPPLLLLGALPPAAAARGPRMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHGGWSRFRVLPQGLKVKEVEREDAGAYVCKATNGFGSLSVNYTLIVMDDTSPGRESPGLDGPSGGQEDPASKQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDIMWMKDDQALTRPEAGEHRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRYNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPPVVPSSSSTSLPWPVVIGIPAGAVFILGTVLLWLCQAKKKPCAPAPAAPMPVHRPPVVARDRDRGGGGGDKDLPAPTALGTGPGVGLCEDLGPPAPPQHLLGPGSAAGPKLYPKLYTDTHTHTHTHSHTHSHVEGKVHQHVHYQC", "length": 510 }, "evidence": [ { "id": "A0A8V0Z469", "url": "https://omabrowser.org/oma/group/A0A8V0Z469/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9THB0-1", "protein_name": "Fibroblast growth factor receptor-like 1", "gene_name": "FGFRL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTPSPALVLPLLLLLGALPPAAAARGPPRMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHGGWSRFRVLPQGLKVKEVEPEDAGAYVCKATNGFGSLSVNYTLIVMDDTSPGRESPGHDSSSGGQEDPASKQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDIMWMKDDQALTRPEAGEHRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRYNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPGAWASPRPQRVPPRQTPPMRTSWAVGCPRPDGSLPAPPRFLLQTQSHQGRPWPPRPPPPACRGRWSSASRPAQSSSWAPWSCGSARPRRSRAPRPPRRLHIARPPQPATAAGIRTCPPPPPWAPAPEWGCVRSLGPRPPPSTCWAPARPPAPSFTPNSTQTRTRTHTHTHTHMWRAKSTSTSTPTTTARVPRAGSWRHGQRQAGAVSPCPVRRTHVDARAHRHTQSDSISPCPVRRTHVDVRAHTDTHTHSQTPSPRAP", "length": 615 }, "evidence": [ { "id": "A0A8V0Z469", "url": "https://omabrowser.org/oma/group/A0A8V0Z469/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7TQM3-1", "protein_name": "Fibroblast growth factor receptor-like 1", "gene_name": "Fgfrl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRSPALLLLLLGALPSAEAARGPPRMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLKVKEVEAEDAGVYVCKATNGFGSLSVNYTLIIMDDISPGKENPGPGGSSGGQEDPVSQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDIMWMKDDQTLTRLEASEHRKKKWTLSLKNLKPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGSEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLISRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPPVAHSSSTTSLPWPVVIGIPAGAVFILGTVLLWLCQTKKKPCAPASTLPVPGHRPPGTSRERSGDKDLPSLAVGICEEHGSTMAPQHILAPGSTAGPKLYPKLYTDVHTHTHTHTCTHTLSCGGQGSSAPACPLSVLNTANLQALCPEVGVWGPRQQVGRIENNGGRVS", "length": 529 }, "evidence": [ { "id": "A0A8V0Z469", "url": "https://omabrowser.org/oma/group/A0A8V0Z469/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N441-1", "protein_name": "Fibroblast growth factor receptor-like 1", "gene_name": "FGFRL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTPSPLLLLLLPPLLLGAFPPAAAARGPPKMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLKVKQVEREDAGVYVCKATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLITRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPPVASSSSATSLPWPVVIGIPAGAVFILGTLLLWLCQAQKKPCTPAPAPPLPGHRPPGTARDRSGDKDLPSLAALSAGPGVGLCEEHGSPAAPQHLLGPGPVAGPKLYPKLYTDIHTHTHTHSHTHSHVEGKVHQHIHYQC", "length": 504 }, "evidence": [ { "id": "A0A8V0Z469", "url": "https://omabrowser.org/oma/group/A0A8V0Z469/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91V87-1", "protein_name": "Fibroblast growth factor receptor-like 1", "gene_name": "Fgfrl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRSPALLLLLLGALPSAEAARGPPRMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLKVKEVEAEDAGVYVCKATNGFGSLSVNYTLIIMDDISPGKESPGPGGSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDIMWMKDDQTLTHLEASEHRKKKWTLSLKNLKPEDSGKYTCRVSNKAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGSEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLISRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPPMASSSSSTSLPWPVVIGIPAGAVFILGTVLLWLCQTKKKPCAPASTLPVPGHRPPGTSRERSGDKDLPSLAVGICEEHGSAMAPQHILASGSTAGPKLYPKLYTDVHTHTHTHTCTHTLSCGGQGSSTPACPLSVLNTANLQALCPEVGIWGPRQQVGRIENNGGRVS", "length": 529 }, "evidence": [ { "id": "A0A8V0Z469", "url": "https://omabrowser.org/oma/group/A0A8V0Z469/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ], "pmid": "" }, { "name": "cell-cell contact zone", "id": "GO:0044291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044291", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "fibroblast growth factor receptor activity", "id": "GO:0005007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005007", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ], "pmid": "" }, { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ], "pmid": "" }, { "name": "fibroblast growth factor binding", "id": "GO:0017134", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017134", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z469", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z469", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z469" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 144, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 322, "end_pos": 324 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z486-1", "uniprot_ac": "A0A8V0Z486", "uniprot_id": "A0A8V0Z486_CHICK", "mass": { "chemical_mass": 123903.0, "monoisotopic_mass": 123903.0 }, "refseq": { "ac": "XP_040536156", "name": "LOW QUALITY PROTEIN: cartilage intermediate layer protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040536156" }, "gene_names": [ { "name": "CILP", "type": "recommended", "evidence": [ { "id": "A0A8V0Z486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486" } ] }, { "name": "CILP", "type": "synonym", "evidence": [ { "id": "XP_040536156", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040536156" } ] } ], "protein_names": [ { "name": "Cartilage intermediate layer protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: cartilage intermediate layer protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040536156", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040536156" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052582.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040536156", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040536156" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z486", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CILP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486", "locus": { "chromosome": "10", "start_pos": 17821084, "end_pos": 17831649, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017715", "url": "https://www.ensembl.org/id/ENSGALG00010017715" } ] } } ], "crossref": [ { "id": "A0A8V0Z486", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z486", "database": "AlphaFoldDB", "categories": [] }, { "id": "415533", "url": "https://www.ncbi.nlm.nih.gov/gene/415533", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RAETPYM", "url": "https://omabrowser.org/oma/group/RAETPYM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2L8", "url": "https://www.orthodb.org/?gene=A0A8V0Z2L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z335", "url": "https://www.orthodb.org/?gene=A0A8V0Z335", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z486", "url": "https://www.orthodb.org/?gene=A0A8V0Z486", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15031", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15031", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15031:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15031:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23591", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23591", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23599", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23599", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23708", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23708", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23730", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23730", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-2404192", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2404192", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040536156", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040536156", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2L8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z335", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z335", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z335-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z335-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z486", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z486-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLVTARGWALMLLLLLGATASSGQRLVRQGLGRIQIGQKTFRPIVMLSLEGRRSSSRRLDPIFTNARRTVLVQDSRKFLSPWSKWSECSGKCGQTGVQKRTRSCLADRLWGVHCNEVMEEGRLCIGHVCSGCNITCPMGRVNADCDACMCEDVTLHGKVSLEDGSPADNARVYLQANNLKLLTTADNKGTFRIPGVCPDGKNTLKIKKAKYTTTAITVPETNRKNLAFQVQLKRSGKPYVFKSPDDKARRVGQSVSLCCNAVGTPAPDRYLWYHNGSLLDPSIYRYKNNLILKNLNRGQAGEYFCKAVSDGGSAKSQPATLSVIGKQEAACSSQPQSHLIRLPHDCFQKATDSFYYDVGKCPAKTCVGKLDKGLRCKDNISYCCGVSKMEVREILCDGYTLPTKVAVECGCKKCTETKITVRGRATAVDNGEPLRFGHIYMGNKRVSMTGYKGTFSVHVPPDTERLVLTFVDRLQKFVNTTKVLPFKENGGAVFHDIKLLRKKAPVMLESTETSVIPLGEKEDDDPIAELEIPPDSFYRKNGEPYRGKVKASVTFLDPRELSTAPVTQSDLNFVDDEGDVFPLRTYGMFSLDFTDEQGTETLNVEDVKVHLDTAQVRMPEHLQEMKLWSLNPETGLWEEEGDFNLEKSRRRRREERTFLVGNMEIKERRLFNLDVPENRRCYVKVRAYRSERFLPSEQIQGVVISVINTEPEPGFSSNPRAWGRFDSVVTGPNGACVPAFCDEQNPEAYAAYILASLGGEELEAVPSAPKLNPNAIGVPQPYLNKLNYRRTDHEDPNTKKTAFRINMAKPSPNSADENNGPIYAYENLKECEEAPYSAAHFRFYRIEGDRYDYNTVPFSEDDLMSWTDDYLAWWPKPMEFRACYIKVKINGPQEVNIRSRNMGGTHPRTIGKLYGIRDVRSIRDPEQQDVSAACLEFKCSGMLFDQDRVDRTLVKVIPQGSCRRESVNSMLHEYLVNHLPMATNNDSSEYTMLAPLDPLGHNYGIYTVTDQDPRIAKEIALGRCFDGTSDGTSRIMKSDIGVALTFTCSERSAAEQSLFESQRNLGQQSIQVPPRESPAYQRPVGSRQITQSRIQMRGQRPSSY", "length": 1104, "header": "tr|A0A8V0Z486-1|A0A8V0Z486_CHICK Isoform 1 of Cartilage intermediate layer protein OS=Gallus gallus OX=9031 GN=CILP PE=1 SV=1 CANONICAL=A0A8V0Z486-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486/entry#A0A8V0Z2L8-1", "sequence": { "sequence": "MLVTARGWALMLLLLLGATASSGQRLVRQGLGRIQIGQKTFRPIVMLSLEAVLVQDSRKFLSPWSKWSECSGKCGQTGVQKRTRSCLADRLWGVHCNEVMEEGRLCIGHVCSGCNITCPMGRVNADCDACMCEDVTLHGKVSLEDGSPADNARVYLQANNLKLLTTADNKGTFRIPGVCPDGKNTLKIKKAKYTTTAITVPETNRKNLAFQVQLKRSGKPYVFKSPDDKARRVGQSVSLCCNAVGTPAPDRYLWYHNGSLLDPSIYRYKNNLILKNLNRGQAGEYFCKAVSDGGSAKSQPATLSVIGKQEAACSSQPQSHLIRLPHDCFQKATDSFYYDVGKCPAKTCVGKLDKGLRCKDNISYCCGVSKMEVREILCDGYTLPTKVAVECGCKKCTETKITVRGRATAVDNGEPLRFGHIYMGNKRVSMTGYKGTFSVHVPPDTERLVLTFVDRLQKFVNTTKVLPFKENGGAVFHDIKLLRKKAPVMLESTETSVIPLGEKEDDDPIAELEIPPDSFYRKNGEPYRGKVKASVTFLDPRELSTAPVTQSDLNFVDDEGDVFPLRTYGMFSLDFTDEQGTETLNVEDVKVHLDTAQVRMPEHLQEMKLWSLNPETGLWEEEGDFNLEKSRRRRREERTFLVGNMEIKERRLFNLDVPENRRCYVKVRAYRSERFLPSEQIQGVVISVINTEPEPGFSSNPRAWGRFDSVVTGPNGACVPAFCDEQNPEAYAAYILASLGGEELEAVPSAPKLNPNAIGVPQPYLNKLNYRRTDHEDPNTKKTAFRINMAKPSPNSADENNGPIYAYENLKECEEAPYSAAHFRFYRIEGDRYDYNTVPFSEDDLMSWTDDYLAWWPKPMEFRACYIKVKINGPQEVNIRSRNMGGTHPRTIGKLYGIRDVRSIRDPEQQDVSAACLEFKCSGMLFDQDRVDRTLVKVIPQGSCRRESVNSMLHEYLVNHLPMATNNDSSEYTMLAPLDPLGHNYGIYTVTDQDPRIAKEIALGRCFDGTSDGTSRIMKSDIGVALTFTCSERSAAEQSLFESQRNLGQQSIQVPPRESPAYQRPVGSRQITQSRIQMRGQRPSSY", "length": 1086, "header": "tr|A0A8V0Z2L8-1|A0A8V0Z486_CHICK Computationally mapped isoform of Cartilage intermediate layer protein OS=Gallus gallus OX=9031 GN=CILP PE=1 SV=1 CANONICAL=A0A8V0Z486-1" }, "locus": { "chromosome": "10", "start_pos": 17830140, "end_pos": 17821835, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042833.1", "url": "https://www.ensembl.org/id/ENSGALT00010042833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025323.1", "url": "https://www.ensembl.org/id/ENSGALP00010025323.1" } ] } }, { "isoform_ac": "A0A8V0Z335-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486/entry#A0A8V0Z335-1", "sequence": { "sequence": "MLVTARGWALMLLLLLGATASSGRRSSSRRLDPIFTNARRTVLVQDSRKFLSPWSKWSECSGKCGQTGVQKRTRSCLADRLWGVHCNEVMEEGRLCIGHVCSGCNITCPMGRVNADCDACMCEDVTLHGKVSLEDGSPADNARVYLQANNLKLLTTADNKGTFRIPGVCPDGKNTLKIKKAKYTTTAITVPETNRKNLAFQVQLKRSGKPYVFKSPDDKARRVGQSVSLCCNAVGTPAPDRYLWYHNGSLLDPSIYRYKNNLILKNLNRGQAGEYFCKAVSDGGSAKSQPATLSVIGKQEAACSSQPQSHLIRLPHDCFQKATDSFYYDVGKCPAKTCVGKLDKGLRCKDNISYCCGVSKMEVREILCDGYTLPTKVAVECGCKKCTETKITVRGRATAVDNGEPLRFGHIYMGNKRVSMTGYKGTFSVHVPPDTERLVLTFVDRLQKFVNTTKVLPFKENGGAVFHDIKLLRKKAPVMLESTETSVIPLGEKEDDDPIAELEIPPDSFYRKNGEPYRGKVKASVTFLDPRELSTAPVTQSDLNFVDDEGDVFPLRTYGMFSLDFTDEQGTETLNVEDVKVHLDTAQVRMPEHLQEMKLWSLNPETGLWEEEGDFNLEKSRRRRREERTFLVGNMEIKERRLFNLDVPENRRCYVKVRAYRSERFLPSEQIQGVVISVINTEPEPGFSSNPRAWGRFDSVVTGPNGACVPAFCDEQNPEAYAAYILASLGGEELEAVPSAPKLNPNAIGVPQPYLNKLNYRRTDHEDPNTKKTAFRINMAKPSPNSADENNGPIYAYENLKECEEAPYSAAHFRFYRIEGDRYDYNTVPFSEDDLMSWTDDYLAWWPKPMEFRACYIKVKINGPQEVNIRSRNMGGTHPRTIGKLYGIRDVRSIRDPEQQDVSAACLEFKCSGMLFDQDRVDRTLVKVIPQGSCRRESVNSMLHEYLVNHLPMATNNDSSEYTMLAPLDPLGHNYGIYTVTDQDPRIAKEIALGRCFDGTSDGTSRIMKSDIGVALTFTCSERSAAEQSLFESQRNLGQQSIQVPPRESPAYQRPVGSRQITQSRIQMRGQRPSSY", "length": 1076, "header": "tr|A0A8V0Z335-1|A0A8V0Z335_CHICK Computationally mapped isoform of Cartilage intermediate layer protein OS=Gallus gallus OX=9031 GN=CILP PE=1 SV=1 CANONICAL=A0A8V0Z486-1" }, "locus": { "chromosome": "10", "start_pos": 17830140, "end_pos": 17821835, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042835.1", "url": "https://www.ensembl.org/id/ENSGALT00010042835.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025325.1", "url": "https://www.ensembl.org/id/ENSGALP00010025325.1" } ] } }, { "isoform_ac": "A0A8V0Z486-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486/entry#A0A8V0Z486-1", "sequence": { "sequence": "MLVTARGWALMLLLLLGATASSGQRLVRQGLGRIQIGQKTFRPIVMLSLEGRRSSSRRLDPIFTNARRTVLVQDSRKFLSPWSKWSECSGKCGQTGVQKRTRSCLADRLWGVHCNEVMEEGRLCIGHVCSGCNITCPMGRVNADCDACMCEDVTLHGKVSLEDGSPADNARVYLQANNLKLLTTADNKGTFRIPGVCPDGKNTLKIKKAKYTTTAITVPETNRKNLAFQVQLKRSGKPYVFKSPDDKARRVGQSVSLCCNAVGTPAPDRYLWYHNGSLLDPSIYRYKNNLILKNLNRGQAGEYFCKAVSDGGSAKSQPATLSVIGKQEAACSSQPQSHLIRLPHDCFQKATDSFYYDVGKCPAKTCVGKLDKGLRCKDNISYCCGVSKMEVREILCDGYTLPTKVAVECGCKKCTETKITVRGRATAVDNGEPLRFGHIYMGNKRVSMTGYKGTFSVHVPPDTERLVLTFVDRLQKFVNTTKVLPFKENGGAVFHDIKLLRKKAPVMLESTETSVIPLGEKEDDDPIAELEIPPDSFYRKNGEPYRGKVKASVTFLDPRELSTAPVTQSDLNFVDDEGDVFPLRTYGMFSLDFTDEQGTETLNVEDVKVHLDTAQVRMPEHLQEMKLWSLNPETGLWEEEGDFNLEKSRRRRREERTFLVGNMEIKERRLFNLDVPENRRCYVKVRAYRSERFLPSEQIQGVVISVINTEPEPGFSSNPRAWGRFDSVVTGPNGACVPAFCDEQNPEAYAAYILASLGGEELEAVPSAPKLNPNAIGVPQPYLNKLNYRRTDHEDPNTKKTAFRINMAKPSPNSADENNGPIYAYENLKECEEAPYSAAHFRFYRIEGDRYDYNTVPFSEDDLMSWTDDYLAWWPKPMEFRACYIKVKINGPQEVNIRSRNMGGTHPRTIGKLYGIRDVRSIRDPEQQDVSAACLEFKCSGMLFDQDRVDRTLVKVIPQGSCRRESVNSMLHEYLVNHLPMATNNDSSEYTMLAPLDPLGHNYGIYTVTDQDPRIAKEIALGRCFDGTSDGTSRIMKSDIGVALTFTCSERSAAEQSLFESQRNLGQQSIQVPPRESPAYQRPVGSRQITQSRIQMRGQRPSSY", "length": 1104, "header": "tr|A0A8V0Z486-1|A0A8V0Z486_CHICK Isoform 1 of Cartilage intermediate layer protein OS=Gallus gallus OX=9031 GN=CILP PE=1 SV=1 CANONICAL=A0A8V0Z486-1" }, "locus": { "chromosome": "10", "start_pos": 17830140, "end_pos": 17821835, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042829.1", "url": "https://www.ensembl.org/id/ENSGALT00010042829.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025319.1", "url": "https://www.ensembl.org/id/ENSGALP00010025319.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-2404192", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-2404192", "resource": "Reactome", "description": "Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BRX8-1", "protein_name": "Cartilage intermediate layer protein", "gene_name": "CILP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSTGPEGKMVGTKAWVFFFLVLEVTSVLGRQMMLTQSVRRVQPGKRTFSIFATPADPLDSPGEWTTWFNIDHPGGQGDYERLDAIRFYYGDRVCARPLRLQARTTSWIPAGSNGQVVHGSPLEGFWCLNREQRPGQNCSNYTVRFLCPPGSLRRDTERSLWSPWSPWSKCSAACGHTGVQTRTRTCLAETVSLCNEATEEGRLCMEQACSACDLTCPMGQVNADCDACMCQDFVLHGAVSLPGGAPASGATVYLLTKTPKLLTQTDRSGRFRVPGLCPDGKSILKITKSKFVPIKLTMPKTRLKTATIKAEFVRAEIPYIVMNPETKARRAGQSVSLCCKATGKPKPEKYFWYHNNTLLEPSLYKHESKLVLRNLQQDQAGEYFCKAQSDAGAVKSLVARLTVIAPDEAPCNPTPESYLIRLPHDCFQNATNSFYYDVGRCPVKTCAGQQDNGIRCRDAVENCCGISKTEEREIQCSGYTLPTKVATECSCQRCTDTRSIVRGRVSAADNGEPMRFGHVYLGNNRVSMTGYKGTFTLHVPQDTERLVLTFVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRRKEPIILEAMETNIIPLGDMDGEDPMGELEIPSKSFYRQNGEPYTGKVKASVTFLDPRNISTATAAQSDLNFINDEGDTFPLRTYGMFSVDFTDEAASESLNVGKVKVHLDSTQVKMPEHVPMMKLWSLNPDTGLWEEEGDFRFESQRRKRREDRTFLVGNMEIRERRLFNLDVPESRRCFIKVRAYRSERFLPSEQIQGVVVSVINLEPRAGFSSNPRAWGRFDSVLTGPNGACLPAFCDDQSPDAYSAYVLASLAGEELEAVESSPKFNPNAIGVPQPYLNKLKYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLQACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVGPLEVNVRSRNMGGTHRQTVGKLYGIRDVKSTRDRDQPNVSSACLEFKCSGMLYDQDRVDRTLVKVIPQGSCHRASVNSMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGSSDGSSRVMKSNVGVALTFNCVERQVGRQSAFQYLQSTSARPSPASTVRGRAPSRRQRASSGSQRQRRGVASLRFPGVAQQPLSN", "length": 1193 }, "evidence": [ { "id": "A0A8V0Z486", "url": "https://omabrowser.org/oma/group/A0A8V0Z486/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M1NUZ8-1", "protein_name": "Cartilage intermediate layer protein 1 isoform X1", "gene_name": "cilp", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCLSTWTFLLLLLGITGTISQGTWRGIMGTSWRPNPAVYHNEDNYEWTTWFNVDHPGGKGDYEKLNVIRYYYRARVCEVPRALEARTTDWIPARSTGERVHADPAVGFWCVNDEQPFGKNCSNYAVRFLCPRDIVSDVEEGIWGQWSDWSLCPAQCDEEATQHRSRSCQSNSKQCSGKSVEARSCHGPPCPRCDLQCIVGTVNSECDGCMCQDHTVLGSVRSAGGLPAPGAAILRAGSSPKLLTVTDHNGHFQVPGICPDGNTTLMVKLSNHAPHQVTVPPSKERTTVLLLRLERAKKLHVLKNPEDRARREGQTAAFCCKIDGTPGPSSYEWFHNGTLLDRSQYQYDETLVLRNLSLDHVGEYYCRGSNENGAIKSKPATLTVIGQKEPSCNPRPDSHLIRLPHDCFQNETNSLYFDVGRCPTTKCTGKLDNGIRCKDSVSYCCGVSNMEEREITCQGYQLPIMVVTQCGCKTCVDTKAIVRGRAVAADTGEPMRFGHIYMDGVKLSRTGYKGTFSIQVPTNTERLVLTFVDNMQKFVNTTKVLPFNPRGGAVFHEVKLLRKKPAVIISSRETNTLDLGEVEGQDPVAEIEIPPNAFYKENGEVFMGNVKASVTFLDPRDVSTAAAAQSDLNFIGDEGDTLPLRTYGMFSVDFRDEEGGESLNAGEVKVRLDAAQVKMPEHLKTMKLWSLNPETGLWEEEGHFYAEKKQRGKREERTFLIGNMEIRERRLFNLDVPENRRCYVKVRAFRSERYMPSEQTEGVVMTLINMEPTPGFSTNPRAWGRFDSVITGPNGACLPAFCDEQKPDAYSAYVMANLGGEELEAVASSPKLNPNTIGVPQPYLNKLNYRRTDHDDPRIKKTAFSINVAKPRSNVAEEANGPVYAFDKLKECEEASFSAAHFRFSRVEGDRYDYNTVPFNEDDPMSWTEDYLSWWPKPMEYRACYIKVKLNSPHELNVRSRNMGGTHPRTVGQLYGIRDTRSIRDMDQATVSAVCLEFKCSGMLYDQDRVDRTLVKVMPQGSCKRDSVNSMLQEYLVNHLPLAVNNDTNEFTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGTSDGTSRVMKSNEGVALTFTCGDKEVTRQSMFQQIQNSLGQATAGSARPGRGNRRQRGSSTAPRSSQRRSTRNSITRSQSLG", "length": 1171 }, "evidence": [ { "id": "A0A8V0Z486", "url": "https://omabrowser.org/oma/group/A0A8V0Z486/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LIQ2-1", "protein_name": "Cartilage intermediate layer protein", "gene_name": "Cilp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAATKTWVLSFLVLEVTTVLGRQMMLTQSARRVQPVKRTPKILTKPVNSQESPGEWTTWFNIDHPGGQGDYERLDAIRFYYGERVCARPLRLEARTTDWMPAGITGQVVHGSPREGFWCLNKEQRPGQNCSNYTVRFLCPPGSLRRDTEHIWSSWSPWSACSAACGHTGVQTRTRTCLAQTVSLCNEATEEGQLCMSQACTACDLTCPMGQVNADCDACMCQDFMLHGAISLPGGGPAPGATVYLLAKAPKMLTQTDSSGSFRVPGLCPDGKTVLKVTKSKFAPIMITMPKTSLKSATINAEFVRAETPYIVMNPETKARRAGQSVSLCCKATGKPSPDKYFWYHNNTLLDPSLYKHQSKLVLRNLQQDQAGEYFCKAQSDAGAVKSKVTQLTVIAHDEAPCNPTPESYLIRLPHDCFQNATNSFYYDVGRCPIKTCAGQQDNGIRCQDAVENCCGISRTEEREIQCSGYTLPTKVAMECSCQRCAETRSIVRGRVTAADDGEPMRFGHVYMGNNRVSMTGYKGTFTLHVPQDTERLVLTFVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRQKEPITLEATETNIIPLGEVAGEDPVAELEIPPKSFYKQNGEPFTGKVKASVTFLDPRNVSTATATQSDLNFINDEGDTFPLRTYGMFSVDFRDEATSESLNAGKVKVHLDSTQVKMPEHARAMKLWSLNPNTGLWEEEGDFKFESQRRNKREERTFLVGNMEIRERRLFNLDVPESRRCFIKVRTYRSERFLPSEQIQGVVVSVINLEPRTGFSSNPRAWGRFDSVITGPNGACLPAFCDDQSPDAYSVYVLASLSGEELEAVESSPKFNPNAIGVPQPYLNKLKYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLRACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVGPLEVNVRSRNMGGTHRQTVGKLYGIRDVKSTRDRDQPNVSSACLEFKCSGMLYDQDRVDRTLVKVIPQGSCHRASVNSMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPGTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCAERQVGRQSAFQYLQSTPARSPATGTVQGRVPAMRQQRASRGGLRRRGSMAPLRFSGVAQQPLSN", "length": 1184 }, "evidence": [ { "id": "A0A8V0Z486", "url": "https://omabrowser.org/oma/group/A0A8V0Z486/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75339-1", "protein_name": "Cartilage intermediate layer protein 1", "gene_name": "CILP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGTKAWVFSFLVLEVTSVLGRQTMLTQSVRRVQPGKKNPSIFAKPADTLESPGEWTTWFNIDYPGGKGDYERLDAIRFYYGDRVCARPLRLEARTTDWTPAGSTGQVVHGSPREGFWCLNREQRPGQNCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDCTACDLTCPMGQVNADCDACMCQDFMLHGAVSLPGGAPASGAAIYLLTKTPKLLTQTDSDGRFRIPGLCPDGKSILKITKVKFAPIVLTMPKTSLKAATIKAEFVRAETPYMVMNPETKARRAGQSVSLCCKATGKPRPDKYFWYHNDTLLDPSLYKHESKLVLRKLQQHQAGEYFCKAQSDAGAVKSKVAQLIVIASDETPCNPVPESYLIRLPHDCFQNATNSFYYDVGRCPVKTCAGQQDNGIRCRDAVQNCCGISKTEEREIQCSGYTLPTKVAKECSCQRCTETRSIVRGRVSAADNGEPMRFGHVYMGNSRVSMTGYKGTFTLHVPQDTERLVLTFVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRRKKPITLEAMETNIIPLGEVVGEDPMAELEIPSRSFYRQNGEPYIGKVKASVTFLDPRNISTATAAQTDLNFINDEGDTFPLRTYGMFSVDFRDEVTSEPLNAGKVKVHLDSTQVKMPEHISTVKLWSLNPDTGLWEEEGDFKFENQRRNKREDRTFLVGNLEIRERRLFNLDVPESRRCFVKVRAYRSERFLPSEQIQGVVISVINLEPRTGFLSNPRAWGRFDSVITGPNGACVPAFCDDQSPDAYSAYVLASLAGEELQAVESSPKFNPNAIGVPQPYLNKLNYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLRACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVGPLEVNVRSRNMGGTHRQTVGKLYGIRDVRSTRDRDQPNVSAACLEFKCSGMLYDQDRVDRTLVKVIPQGSCRRASVNPMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCVERQVGRQSAFQYLQSTPAQSPAAGTVQGRVPSRRQQRASRGGQRQGGVVASLRFPRVAQQPLIN", "length": 1184 }, "evidence": [ { "id": "A0A8V0Z486", "url": "https://omabrowser.org/oma/group/A0A8V0Z486/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q66K08-1", "protein_name": "Cartilage intermediate layer protein 1", "gene_name": "Cilp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAIKTWVFSFLVLEVTTVLGRQTMLAQSVRRVQPVKRTPKTLAKPADSQESPGEWTTWFNIDHPGGQGDYERLDAIRFYYGERVCARPLRLEARTTDWMPAGSTGQVVHGSPREGFWCLNREQRPGQNCSNYTVRFLCPPGSLRGDAEHIWSSWSPWSKCSAACGHTGVQTRTRTCLAQTVSLCSEATEEGQLCMSQACTACDLTCPMGQVNADCDACMCQDFMLHGAISLPGGGPAPGAAVYLLAKAPKMLTRTDSSGRFRVPGLCPDGKTILKITKTKFAPIMITMPKTSLKSATINAEFVRAETPYIVMNPEMKARRAGQSVSLCCKATGKPSPDKYFWYHNNTLLDPSLYKHESKLVLRNLQQDQAGEYFCKAQSDAGAVKSKVTQLTVIAHDETPCNPTPESYLIRLPHDCFQNASNSFYYDVGRCPIKTCAGQQDNGIRCRDAVENCCGISRTEEREIQCSGYTLPTKVAVECSCQRCAETRSIVRGRVTATDNGEPMRFGHVYMGNNRVSMTGYKGTFTLHIPQDTERLVLTFVDRLQKFVNTTKVLPFNKKGSAVFHEIKMLRQKEPITLEAMETNIIPLGEVIGEDPVAELEIPSKSFYRQNGEPFTGKVKASVTFLDPRNISTATAAQSDLNFINDEGDTFPLRTYGMFSVDFRDEATSESLNAGKVKVHLDSTQVKMPEHVPAMKLWSLNPDTGLWEEEGDFKFESQRRNKREERTFLVGNMEIRERRLFNLDVPESRRCFIKVRTYRSERFLPSEQIQGVVVSVINLEPRTGFSSNPRAWGRFDSVITGPNGACLPAFCDDQSPDAYSVYVLASLSGEELEAVESSPKFNPNAIGVPQPYLNKLKYRRTDHEDPRVKKTAFQISMAKPRPNSAEESNGPIYAFENLRACEEAPPSAAHFRFYQIEGDRYDYNTVPFNEDDPMSWTEDYLAWWPKPMEFRACYIKVKIVGPLEVNVRSRNMGGTHRQTVGKLYGIRDVKSTRDRDQPNVSSACLEFKCSGMLYDQDRVDRTLVKVIPQGSCHRASVNSMLHEYLVNHLPLAVNNDTSEYTMLAPLDPLGHNYGIYTVTDQDPRTAKEIALGRCFDGTSDGSSRIMKSNVGVALTFNCAERQVGRQSAFQYLQSTPARSPATGTVQGRVPAMRQQRASRGGLRRRGSMAPLRFSGVAQQPLSN", "length": 1184 }, "evidence": [ { "id": "A0A8V0Z486", "url": "https://omabrowser.org/oma/group/A0A8V0Z486/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z486", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z486", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z486", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z486", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486" } ], "pmid": "" }, { "name": "negative regulation of insulin-like growth factor receptor signaling pathway", "id": "GO:0043569", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043569", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z486", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486" } ], "pmid": "" }, { "name": "negative regulation of SMAD protein signal transduction", "id": "GO:0060392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060392", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z486", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 985, "end_pos": 987, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z486", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z486" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 238, "end_pos": 322, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 479, "end_pos": 481 }, { "start_pos": 985, "end_pos": 987 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z372-1", "uniprot_ac": "A0A8V0Z372", "uniprot_id": "A0A8V0Z372_CHICK", "mass": { "chemical_mass": 23865.0, "monoisotopic_mass": 23865.0 }, "refseq": { "ac": "NP_001264477", "name": "rho-related GTP-binding protein RhoJ isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264477" }, "gene_names": [ { "name": "RHOJ", "type": "recommended", "evidence": [ { "id": "A0A8V0Z372", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z372" } ] }, { "name": "RHOJ", "type": "synonym", "evidence": [ { "id": "NP_001264477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264477" } ] } ], "protein_names": [ { "name": "Ras homolog family member J", "type": "synonym", "evidence": [ { "id": "A0A8V0Z372", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z372/entry#names_and_taxonomy" } ] }, { "name": "ras homolog gene family, member J", "type": "synonym", "evidence": [ { "id": "NP_001264477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264477" } ] }, { "name": "rho-related GTP-binding protein RhoJ isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001264477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264477" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01047283.1, BX929287.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000215.1. On Apr 11, 2013 this sequence version replaced XP_421413.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001264477", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264477" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z372", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z372" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RHOJ", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z372", "locus": { "chromosome": "5", "start_pos": 52922366, "end_pos": 52967227, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017732", "url": "https://www.ensembl.org/id/ENSGALG00010017732" } ] } } ], "crossref": [ { "id": "A0A8V0Z372", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z372", "database": "AlphaFoldDB", "categories": [] }, { "id": "423513", "url": "https://www.ncbi.nlm.nih.gov/gene/423513", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423513", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423513", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ARMNCKE", "url": "https://omabrowser.org/oma/group/ARMNCKE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2Q4", "url": "https://www.orthodb.org/?gene=A0A8V0Z2Q4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z372", "url": "https://www.orthodb.org/?gene=A0A8V0Z372", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013409", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001264477", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264477", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Q4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z372", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z372", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z372-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z372-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCKAEGEDCTDGSSNSTKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGQQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKVCMPNVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKEIGAQCYLECSALTQKGLKTVFDEAILTIFHPKKKKKHCAKCHRCCTIV", "length": 214, "header": "tr|A0A8V0Z372-1|A0A8V0Z372_CHICK Isoform 1 of Ras homolog family member J OS=Gallus gallus OX=9031 GN=RHOJ PE=3 SV=1 CANONICAL=A0A8V0Z372-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z372/entry#A0A8V0Z2Q4-1", "sequence": { "sequence": "MPSPRSTCPPCLTTMQVDWKPLPKLNESLHFIAIPSTIHHVSAVSETQPVTVTVGGQQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKVCMPNVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKEIGAQCYLECSALTQKGLKTVFDEAILTIFHPKKKKKHCAKCHRCCTIV", "length": 204, "header": "tr|A0A8V0Z2Q4-1|A0A8V0Z372_CHICK Computationally mapped isoform of Ras homolog family member J OS=Gallus gallus OX=9031 GN=RHOJ PE=3 SV=1 CANONICAL=A0A8V0Z372-1" }, "locus": { "chromosome": "5", "start_pos": 52966445, "end_pos": 52922685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042868.1", "url": "https://www.ensembl.org/id/ENSGALT00010042868.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025358.1", "url": "https://www.ensembl.org/id/ENSGALP00010025358.1" } ] } }, { "isoform_ac": "A0A8V0Z372-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z372/entry#A0A8V0Z372-1", "sequence": { "sequence": "MSCKAEGEDCTDGSSNSTKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGQQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKVCMPNVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKEIGAQCYLECSALTQKGLKTVFDEAILTIFHPKKKKKHCAKCHRCCTIV", "length": 214, "header": "tr|A0A8V0Z372-1|A0A8V0Z372_CHICK Isoform 1 of Ras homolog family member J OS=Gallus gallus OX=9031 GN=RHOJ PE=3 SV=1 CANONICAL=A0A8V0Z372-1" }, "locus": { "chromosome": "5", "start_pos": 52966575, "end_pos": 52922685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042870.1", "url": "https://www.ensembl.org/id/ENSGALT00010042870.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025360.1", "url": "https://www.ensembl.org/id/ENSGALP00010025360.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 61, "start_aa": "Thr", "end_pos": 61, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr61", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 63, "start_aa": "Thr", "end_pos": 63, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr63", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:423513", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423513", "resource": "KEGG Pathway" }, { "id": "R-GGA-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W6Z9-1", "protein_name": "Ras homolog family member J", "gene_name": "RHOJ", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNCQEGKDRSCGCGHEEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELRDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKKRCSECHSCCSII", "length": 213 }, "evidence": [ { "id": "A0A8V0Z372", "url": "https://omabrowser.org/oma/group/A0A8V0Z372/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5TZD5-1", "protein_name": "Rho-related GTP-binding protein RhoJ", "gene_name": "rhoj", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTLSSKSRQNALEAAEDGGSNSDPVNTTAKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYIPTVFDHYAVNVTVSGRQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELRSCMPHVPYILIGTQIDLRDDPKTLARLLQMKEKPLTYEQGLKLAREIGAQCYLECSALTQKGLKTVFDEAILTIFSPKKQKRGCAACRCCCALV", "length": 226 }, "evidence": [ { "id": "A0A8V0Z372", "url": "https://omabrowser.org/oma/group/A0A8V0Z372/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9ER71-1", "protein_name": "Rho-related GTP-binding protein RhoJ", "gene_name": "Rhoj", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCRERTDSSCGCNGHEENRILKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKKGCLGCHGCCAII", "length": 214 }, "evidence": [ { "id": "A0A8V0Z372", "url": "https://omabrowser.org/oma/group/A0A8V0Z372/", "database": "OMA" } ], "glygen_name": 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"MSASRFIKCVTVGDGAVGKTCLLISYTSNTFPTDYVPTVFDNFSANVVVNGATVNLGLWDTAGQEDYNRLRPLSYRGADVFILAFSLISKASYENVSKKWIPELKHYAPGVPIVLVGTKLDLRDDKQFFIDHPGAVPITTVQGEELKKLIGAPAYIECSSKSQENVKGVFDAAIRVVLQPPKQKKKKNKAQKACSIL", "length": 197 }, "evidence": [ { "id": "A0A8V0Z372", "url": "https://omabrowser.org/oma/group/A0A8V0Z372/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z372", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z372" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z372", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z372" } ], "pmid": "" }, { "name": "protein kinase 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"https://alphafold.ebi.ac.uk/entry/A0A8V0Z4F1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR009906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2S7", "url": "https://www.orthodb.org/?gene=A0A8V0Z2S7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4F1", "url": "https://www.orthodb.org/?gene=A0A8V0Z4F1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA82", "url": "https://www.orthodb.org/?gene=A0A8V0ZA82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA89", "url": "https://www.orthodb.org/?gene=A0A8V0ZA89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32022", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32022", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32022:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32022:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07286", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07286", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "22360", "url": "https://www.rhea-db.org/rhea/22360", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z2S7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2S7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA82", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA89", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA89-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLTGGLKSLLPHARRRIIHCNRLRISNISGMAEGYKQASVVILHKSLADDFEKFCHANSGALPLLYRSKPGEWKCPSLSSDSDTRTDCLQYRKYEHGAFTGSLRSLKDYSEQLKDMVAFYLGCSSNFEKVLQAAGIPVRNIEQKCNITVPCYSISNFCCNLVVAMRPIPESKLEAAVLATSELKEAPGAPIHMGNPGLLGIQDLSKPDYGDSVHLQPGDIPVFWACSVTGIEAVINCRSPLAFTHSFGYMFNTDLKNDRFALRSSREVPQVHCISQDPLHYSMVSAEAAKKIKTLESLIGIDPGNRGIVHLLRPGELLKTCLSLSHARSVLITTGFPTHFNYEPPEENDGPPGALAIAAMLQALEKDVAIVTDQRATDLNKKIIEEAVQIGILKEPVPLLSYQRESANSALTFLCENGNPRRPRFDHLIAIERAGMAADGNYYNARKVNIKHLVDPIDELFLAAQTIPGITTTGVGDGGNELGMGKVKDSVKKHIKNGDVIACDVAADFAVVAGVSNWGGYAIACALYILSTCEIHNCYLRRAVGFSQSPKKTVWLSALPSVTKEEKLLKALVQLGVRSGASASLEMEVDALPFYNTHAPLIEKLLHEVQH", "length": 612, "header": "tr|A0A8V0Z4F1-1|A0A8V0Z4F1_CHICK Isoform 1 of D-glutamate cyclase, mitochondrial OS=Gallus gallus OX=9031 GN=C14orf159 PE=1 SV=1 CANONICAL=A0A8V0Z4F1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2S7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1/entry#A0A8V0Z2S7-1", "sequence": { "sequence": "MLLTGGLKSLLPHARRRIIHCNRLRISNISGMAEGYKQASVVILHKSLADDFEKFCHANSGALPLLYRSKPGEWKCPSLSSDSDTRTDCLQYRKYEHGAFTGSLRSLKDYSEQLKDMVAFYLGCSSNFEKVLQAAGIPVRNIEQKCNISMYKTAVPCYSISNFCCNLVVAMRPIPESKLEAAVLATSELKEAPGAPIHMGNPGLLGIQDLSKPDYGDSVHLQPGDIPVFWACSVTGIEAVINCRSPLAFTHSFGYMFNTDLKNDRFALRSSREVPQVHCISQDPLHYSMVSAEAAKKIKTLESLIGIDPGNRGIVHLLRPGELLKTCLSLSHARSVLITTGFPTHFNYEPPEENDGPPGALAIAAMLQALEKDVAIVTDQRATDLNKKIIEEAVQIGILKEPVPLLSYQRESANSALTFLCENGNPRRPRFDHLIAIERAGMAADGNYYNARKVNIKHLVDPIDELFLAAQTIPGITTTGVGDGGNELGMGKVKDSVKKHIKNGDVIACDVAADFAVVAGVSNWGGYAIACALYILSTCEIHNCYLRRAVGFSQSPKKTVWLSALPSVTKSLLFFCCLLTTPG", "length": 583, "header": "tr|A0A8V0Z2S7-1|A0A8V0Z4F1_CHICK Computationally mapped isoform of D-glutamate cyclase, mitochondrial OS=Gallus gallus OX=9031 GN=C14orf159 PE=1 SV=1 CANONICAL=A0A8V0Z4F1-1" }, "locus": { "chromosome": "5", "start_pos": 43739792, "end_pos": 43721821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042888.1", "url": "https://www.ensembl.org/id/ENSGALT00010042888.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025378.1", "url": "https://www.ensembl.org/id/ENSGALP00010025378.1" } ] } }, { "isoform_ac": "A0A8V0Z4F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1/entry#A0A8V0Z4F1-1", "sequence": { "sequence": "MLLTGGLKSLLPHARRRIIHCNRLRISNISGMAEGYKQASVVILHKSLADDFEKFCHANSGALPLLYRSKPGEWKCPSLSSDSDTRTDCLQYRKYEHGAFTGSLRSLKDYSEQLKDMVAFYLGCSSNFEKVLQAAGIPVRNIEQKCNITVPCYSISNFCCNLVVAMRPIPESKLEAAVLATSELKEAPGAPIHMGNPGLLGIQDLSKPDYGDSVHLQPGDIPVFWACSVTGIEAVINCRSPLAFTHSFGYMFNTDLKNDRFALRSSREVPQVHCISQDPLHYSMVSAEAAKKIKTLESLIGIDPGNRGIVHLLRPGELLKTCLSLSHARSVLITTGFPTHFNYEPPEENDGPPGALAIAAMLQALEKDVAIVTDQRATDLNKKIIEEAVQIGILKEPVPLLSYQRESANSALTFLCENGNPRRPRFDHLIAIERAGMAADGNYYNARKVNIKHLVDPIDELFLAAQTIPGITTTGVGDGGNELGMGKVKDSVKKHIKNGDVIACDVAADFAVVAGVSNWGGYAIACALYILSTCEIHNCYLRRAVGFSQSPKKTVWLSALPSVTKEEKLLKALVQLGVRSGASASLEMEVDALPFYNTHAPLIEKLLHEVQH", "length": 612, "header": "tr|A0A8V0Z4F1-1|A0A8V0Z4F1_CHICK Isoform 1 of D-glutamate cyclase, mitochondrial OS=Gallus gallus OX=9031 GN=C14orf159 PE=1 SV=1 CANONICAL=A0A8V0Z4F1-1" }, "locus": { "chromosome": "5", "start_pos": 43743032, "end_pos": 43721821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042894.1", "url": "https://www.ensembl.org/id/ENSGALT00010042894.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025384.1", "url": "https://www.ensembl.org/id/ENSGALP00010025384.1" } ] } }, { "isoform_ac": "A0A8V0ZA82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1/entry#A0A8V0ZA82-1", "sequence": { "sequence": "MLLTGGLKSLLPHARRRIIHCNRLRISNISGMAEGYKQASVVILHKSLADDFEKFCHANSGALPLLYRSKPGEWKCPSLSSDSDTRTDCLQYRKYEHGAFTGSLRSLKDYSEQLKDMVAFYLGCSSNFEKVLQAAGIPVRNIEQKCNISMYKTAVPCYSISNFCCNLVVAMRPIPESKLEAAVLATSELKEAPGAPIHMGNPGLLGIQDLSKPDYGDSVHLQPGDIPVFWACSVTGIEAVINCRSPLAFTHSFGYMFNTDLKNDRFALRSSREVPQVHCISQDPLHYSMVSAEAAKKIKTLESLIGIDPGNRGIVHLLRPGELLKTCLSLSHARSVLITTGFPTHFNYEPPEENDGPPGALAIAAMLQALEKDVAIVTDQRATDLNKKIIEEAVQIGILKEPVPLLSYQRESANSALTFLCENGNPRRPRFDHLIAIERAGMAADGNYYNARKVNIKHLVDPIDELFLAAQTIPGITTTGVGDGGNELGMGKVKDSVKKHIKNGDVIACDVAADFAVVAGVSNWGGYAIACALYILSTCEIHNCYLRRAVGFSQSPKKTVWLSALPSVTKKSF", "length": 573, "header": "tr|A0A8V0ZA82-1|A0A8V0Z4F1_CHICK Computationally mapped isoform of D-glutamate cyclase, mitochondrial OS=Gallus gallus OX=9031 GN=C14orf159 PE=1 SV=1 CANONICAL=A0A8V0Z4F1-1" }, "locus": { "chromosome": "5", "start_pos": 43742904, "end_pos": 43721821, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042887.1", "url": "https://www.ensembl.org/id/ENSGALT00010042887.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025377.1", "url": "https://www.ensembl.org/id/ENSGALP00010025377.1" } ] } }, { "isoform_ac": "A0A8V0ZA89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1/entry#A0A8V0ZA89-1", "sequence": { "sequence": "MWTLYQKFTVLGATVCSLALNSTLNNFTIPGYKQASVVILHKSLADDFEKFCHANSGALPLLYRSKPGEWKCPSLSSDSDTRTDCLQYRKYEHGAFTGSLRSLKDYSEQLKDMVAFYLGCSSNFEKVLQAAGIPVRNIEQKCNISMYKTAVPCYSISNFCCNLVVAMRPIPESKLEAAVLATSELKEAPGAPIHMGNPGLLGIQDLSKPDYGDSVHLQPGDIPVFWACSVTGIEAVINCRSPLAFTHSFGYMFNTDLKNDRFALRSSREVPQVHCISQDPLHYSMVSAEAAKKIKTLESLIGIDPGNRGIVHLLRPGELLKTCLSLSHARSVLITTGFPTHFNYEPPEENDGPPGALAIAAMLQALEKDVAIVTDQRATDLNKKIIEEAVQIGILKEPVPLLSYQRESANSALTFLCENGNPRRPRFDHLIAIERAGMAADGNYYNARKVNIKHLVDPIDELFLAAQTIPGITTTGVGDGGNELGMGKVKDSVKKHIKNGDVIACDVAADFAVVAGVSNWGGYAIACALYILSTCEIHNCYLRRAVGFSQSPKKTVWLSALPSVTKEEKLLKALVQLGVRSGASASLEMEVDALPFYNTHAPLIEKLLHEVQH", "length": 613, "header": "tr|A0A8V0ZA89-1|A0A8V0Z4F1_CHICK Computationally mapped isoform of D-glutamate cyclase, mitochondrial OS=Gallus gallus OX=9031 GN=C14orf159 PE=1 SV=1 CANONICAL=A0A8V0Z4F1-1" }, "locus": { "chromosome": "5", "start_pos": 43743032, "end_pos": 43725646, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042892.1", "url": "https://www.ensembl.org/id/ENSGALT00010042892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025382.1", "url": "https://www.ensembl.org/id/ENSGALP00010025382.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "D-glutamate cyclase activity", "id": "GO:0047820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047820", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4F1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4F1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4F1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glutamate metabolic process", "id": "GO:0006536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4F1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22360", "name": "", "equation": "D-glutamate = 5-oxo-D-proline + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0Z4F1-1" ], "evidence": [ { "id": "22360", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22360" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8V0Z4F1", "gene_name": "C14orf159", "activity": [ { "ec_number": "4.2.1.48", "activity": "D-glutamate = 5-oxo-D-proline + H2O.", "evidence": [ { "id": "A0A8V0Z4F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1" } ] }, { "ec_number": "4.2.1.48", "activity": "", "evidence": [ { "id": "A0A8V0Z4F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4F1" }, { "id": "PF14336", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14336" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "D-glutamate cyclase-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 296, "end_pos": 606, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.2.1.48", "ec_name": "D-glutamate = 5-oxo-D-proline + H2O.", "evidence": [ { "id": "4.2.1.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.48" }, { "id": "4.2.1.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.1.48" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 28, "end_pos": 30 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3V5-1", "uniprot_ac": "A0A8V0Z3V5", "uniprot_id": "A0A8V0Z3V5_CHICK", "mass": { "chemical_mass": 39614.0, "monoisotopic_mass": 39614.0 }, "refseq": {}, "gene_names": [ { "name": "SFXN3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5" } ] } ], "protein_names": [ { "name": "Sidoreflexin", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D9#function" }, { "database": "UniProtKB", "id": "ARBA00045398", "url": "https://www.uniprot.org/uniprotkb/ARBA00045398#function" }, { "database": "UniProtKB", "id": "A0A8V0ZBB9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBB9#function" }, { "database": "UniProtKB", "id": "A0A8V0Z3V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5#function" }, { "database": "UniProtKB", "id": "A0A8V0ZBC5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBC5#function" }, { "database": "UniProtKB", "id": "A0A8V0Z3W5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": 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"A0A8V0Z3W5", "url": "https://www.orthodb.org/?gene=A0A8V0Z3W5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4D9", "url": "https://www.orthodb.org/?gene=A0A8V0Z4D9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBB9", "url": "https://www.orthodb.org/?gene=A0A8V0ZBB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBC5", "url": "https://www.orthodb.org/?gene=A0A8V0ZBC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11153:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11153:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "35031", "url": "https://www.rhea-db.org/rhea/35031", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z3V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3W5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4D9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"database": "Ensembl Peptide", "id": "ENSGALP00010025781.1", "url": "https://www.ensembl.org/id/ENSGALP00010025781.1" } ] } }, { "isoform_ac": "A0A8V0Z3W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5/entry#A0A8V0Z3W5-1", "sequence": { "sequence": "MPPTLPTTIDIREPRWDQSTFQGRAKHFFTVTDPRNLLLSGAALDEARRLVLAYRAGTVPPGLTEDELWRAKYIYDSAFHPDTGEKMLLIGRMSAQVPMNMTITGCMLTFYRTTPAVVFWQWVNQSFNAIVNYTNRSGDAPITPSQLGTAYVSATGGAVVTALGLKSLTKHLPAIIGRYVPFAAVAAANCINIPLMRQRELKVGIPITDENGNRLGESTAAAQKAIFQVVVSRIGMAAPAMAIPPVIMNVLEKRAFLKRYPYLNAPLQGHSGVPTLGNIMWWLRCWCPCKLRPTSYQVSPLLAVTQRVSHIQCVCGCVEAVSHGIPQARA", "length": 330, "header": "tr|A0A8V0Z3W5-1|A0A8V0Z3W5_CHICK Computationally mapped isoform of Sidoreflexin OS=Gallus gallus OX=9031 GN=SFXN3 PE=1 SV=1 CANONICAL=A0A8V0Z3V5-1" }, "locus": { "chromosome": "6", "start_pos": 23858932, "end_pos": 23856334, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043391.1", "url": "https://www.ensembl.org/id/ENSGALT00010043391.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025791.1", "url": "https://www.ensembl.org/id/ENSGALP00010025791.1" } ] } }, { "isoform_ac": "A0A8V0Z4D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5/entry#A0A8V0Z4D9-1", "sequence": { "sequence": "MPPTLPTTIDIREPRWDQSTFQGRAKHFFTVTDPRNLLLSGAALDEARRLVLAYRAGTVPPGLTEDELWRAKYIYDSAFHPDTGEKMLLIGRMSAQVPMNMTITGCMLTFYRELKVGIPITDENGNRLAIPPVIMNVLEKRAFLKRYPYLNAPLQVGLVGLCLVFATPLCCALFPQKSSMQVSRLEPSVQAQIREVDPQLHTVYFNKGL", "length": 209, "header": "tr|A0A8V0Z4D9-1|A0A8V0Z3V5_CHICK Computationally mapped isoform of Sidoreflexin OS=Gallus gallus OX=9031 GN=SFXN3 PE=1 SV=1 CANONICAL=A0A8V0Z3V5-1" }, "locus": { "chromosome": "6", "start_pos": 23858932, "end_pos": 23856862, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043386.1", "url": "https://www.ensembl.org/id/ENSGALT00010043386.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025788.1", "url": "https://www.ensembl.org/id/ENSGALP00010025788.1" } ] } }, { "isoform_ac": "A0A8V0ZBB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5/entry#A0A8V0ZBB9-1", "sequence": { "sequence": "MPPTLPTTIDIREPRWDQSTFQGRAKHFFTVTDPRNLLLSGAALDEARRLVLAYRAGTVPPGLTEDELWRAKYIYDSAFHPDTGEKMLLIGRMSAQVPMNMTITGCMLTFYRTTPAVVFWQWVNQSFNAIVNYTNRSGDAPITPSVFPISSVYVAVSRLCPMASPRLEPEMDAPTLGHGILRTRPPEARGEHYGMYSAAGGLLQPGCACAAPRALCSVLIPGCNLDFPGANGTF", "length": 234, "header": "tr|A0A8V0ZBB9-1|A0A8V0Z3V5_CHICK Computationally mapped isoform of Sidoreflexin OS=Gallus gallus OX=9031 GN=SFXN3 PE=1 SV=1 CANONICAL=A0A8V0Z3V5-1" }, "locus": { "chromosome": "6", "start_pos": 23858932, "end_pos": 23856138, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043383.1", "url": "https://www.ensembl.org/id/ENSGALT00010043383.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025785.1", "url": "https://www.ensembl.org/id/ENSGALP00010025785.1" } ] } }, { "isoform_ac": "A0A8V0ZBC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5/entry#A0A8V0ZBC5-1", "sequence": { "sequence": "MPPTLPTTIDIREPRWDQSTFQGRAKHFFTVTDPRNLLLSGAALDEARRLVLAYRAGTVPPGLTEDELWRAKYIYDSAFHPDTGEKMLLIGRMSAQVPMNMTITGCMLTFYRTTPAVVFWQWVNQSFNAIVNYTNRSGDAPITPSQLGTAYVSATGGAVVTALGLKSLTKHLPAIIGRYVPFAAVAAANCINIPLMRQRELKVGIPITDENGNRLGESTAAAQKAIFQVVVSRIGMAAPAMAVPVPERPPAGWPGGTLLGVCNPAVLRALPAEELDAGEPPGAQRPSSDPGGGPAAAHRLLQQGAVSTGLLHR", "length": 313, "header": "tr|A0A8V0ZBC5-1|A0A8V0Z3V5_CHICK Computationally mapped isoform of Sidoreflexin OS=Gallus gallus OX=9031 GN=SFXN3 PE=1 SV=1 CANONICAL=A0A8V0Z3V5-1" }, "locus": { "chromosome": "6", "start_pos": 23858932, "end_pos": 23856839, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043390.1", "url": "https://www.ensembl.org/id/ENSGALT00010043390.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025790.1", "url": "https://www.ensembl.org/id/ENSGALP00010025790.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 143, "start_aa": "Thr", "end_pos": 143, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr143", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "amino acid transport", "id": "GO:0006865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006865", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5" } ], "pmid": "" }, { "name": "serine import into mitochondrion", "id": "GO:0140300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140300", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "monoatomic ion transmembrane transporter activity", "id": "GO:0015075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015075", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5" } ], "pmid": "" }, { "name": "L-serine transmembrane transporter activity", "id": "GO:0015194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015194", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3V5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "35031", "name": "", "equation": "L-serine(in) = L-serine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "35031", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/35031" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 143 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 100, "end_pos": 102 }, { "start_pos": 124, "end_pos": 126 }, { "start_pos": 132, "end_pos": 134 }, { 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4I9-1", "uniprot_ac": "A0A8V0Z4I9", "uniprot_id": "A0A8V0Z4I9_CHICK", "mass": { "chemical_mass": 56084.0, "monoisotopic_mass": 56084.0 }, "refseq": { "ac": "XP_015148748", "name": "monocarboxylate transporter 2-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148748" }, "gene_names": [ { "name": "LOC416086", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9" } ] }, { "name": "LOC416086", "type": "synonym", "evidence": [ { "id": "XP_015148748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148748" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9/entry#names_and_taxonomy" } ] }, { "name": "monocarboxylate transporter 2-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_015148748", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148748" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015148748.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015148748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148748" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC416086", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z4I9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4I9", "database": "AlphaFoldDB", "categories": [] }, { "id": "416086", "url": "https://www.ncbi.nlm.nih.gov/gene/416086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416086", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RIMNGIS", "url": "https://omabrowser.org/oma/group/RIMNGIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4I9", "url": "https://www.orthodb.org/?gene=A0A8V0Z4I9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB52", "url": "https://www.orthodb.org/?gene=A0A8V0ZB52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB60", "url": "https://www.orthodb.org/?gene=A0A8V0ZB60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHU0", "url": "https://www.orthodb.org/?gene=A0A8V0ZHU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHU9", "url": "https://www.orthodb.org/?gene=A0A8V0ZHU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360:SF92", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360:SF92", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015148748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015148748", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "71779", "url": "https://www.rhea-db.org/rhea/71779", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "71783", "url": "https://www.rhea-db.org/rhea/71783", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z4I9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB52", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB60", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHU0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHU9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPHSDAGPVAGPPDGGWGWVVVFGAFISIGFAYAFPKGIAIFYKEIQDFFDTSYSEIAWVSSIMLATTYGAGPISSILVNRYGSRPVVILGGLLCGIGMVSAAFCTSIIQLYICVGFITGLGLALNLQPSVIIIGRYFLKRRPIANGLAMAGSPVMLCTLAPLNQFLFDNYGWRGSFLILGAILLHCCVAGALFRPISADKASVKTQSIEEGKEVLKEEVTKDVIEMNSPTNVRMETKTEEEEERDCCEKVNKYLDFSLFKHRGFLIYLIGNVLMFLGFFAPIVFLAPYAKHIGIDEYSAAFLLSILAIVDMVARPTTGIIANSKWVRPRIQYFFSFSIAFNGTCHLLCPLASGYTGLVIYSVFFGLAFGMVCAMLFETLMDLVGASRFTSAVGLVTIAECCTILLGPPIGGTLIDTFGDYKYMFIKCGAVMVLAGTFLFIMNYYNYRMLAKEEKKRKAKEEDTKPVRTENEGRNNWNKEHVQDGPELEPLREEQEGLKKEANGTNEV", "length": 509, "header": "tr|A0A8V0Z4I9-1|A0A8V0Z4I9_CHICK Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC416086 PE=3 SV=1 CANONICAL=A0A8V0Z4I9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9/entry#A0A8V0Z4I9-1", "sequence": { "sequence": "MPPHSDAGPVAGPPDGGWGWVVVFGAFISIGFAYAFPKGIAIFYKEIQDFFDTSYSEIAWVSSIMLATTYGAGPISSILVNRYGSRPVVILGGLLCGIGMVSAAFCTSIIQLYICVGFITGLGLALNLQPSVIIIGRYFLKRRPIANGLAMAGSPVMLCTLAPLNQFLFDNYGWRGSFLILGAILLHCCVAGALFRPISADKASVKTQSIEEGKEVLKEEVTKDVIEMNSPTNVRMETKTEEEEERDCCEKVNKYLDFSLFKHRGFLIYLIGNVLMFLGFFAPIVFLAPYAKHIGIDEYSAAFLLSILAIVDMVARPTTGIIANSKWVRPRIQYFFSFSIAFNGTCHLLCPLASGYTGLVIYSVFFGLAFGMVCAMLFETLMDLVGASRFTSAVGLVTIAECCTILLGPPIGGTLIDTFGDYKYMFIKCGAVMVLAGTFLFIMNYYNYRMLAKEEKKRKAKEEDTKPVRTENEGRNNWNKEHVQDGPELEPLREEQEGLKKEANGTNEV", "length": 509, "header": "tr|A0A8V0Z4I9-1|A0A8V0Z4I9_CHICK Isoform 1 of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC416086 PE=3 SV=1 CANONICAL=A0A8V0Z4I9-1" }, "locus": { "chromosome": "12", "start_pos": 14840244, "end_pos": 14825151, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047548.1", "url": "https://www.ensembl.org/id/ENSGALT00010047548.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028154.1", "url": "https://www.ensembl.org/id/ENSGALP00010028154.1" } ] } }, { "isoform_ac": "A0A8V0ZB52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9/entry#A0A8V0ZB52-1", "sequence": { "sequence": "MELLCWGGAFTQYRCLPAVMKVVIPGPGTVIITATVWHGTHCHPHTVQIDFLFLFSSRSHTGSCQQHPGVIILLVLPALCQTCPLQGPHFSLSPGPISSILVNRYGSRPVVILGGLLCGIGMVSAAFCTSIIQLYICVGFITGLGLALNLQPSVIIIGRYFLKRRPIANGLAMAGSPVMLCTLAPLNQFLFDNYGWRGSFLILGAILLHCCVAGALFRPISADKASVKTQSIEEGKEVLKEEVTKDVIEMNSPTNVRMETKTEEEEERDCCEKVNKYLDFSLFKHRGFLIYLIGNVLMFLGFFAPIVFLAPYAKHIGIDEYSAAFLLSILAIVDMVARPTTGIIANSKWVRPRIQYFFSFSIAFNGTCHLLCPLASGYTGLVIYSVFFGLAFGMVCAMLFETLMDLVGASRFTSAVGLVTIAECCTILLGPPIGGTLIDTFGDYKYMFIKCGAVMVLAGTFLFIMNYYNYRMLAKEEKKRKAKEEDTKPVRTENEGRNNWNKEHVQDGPELEPLREEQEGLKKEANGTNEV", "length": 531, "header": "tr|A0A8V0ZB52-1|A0A8V0Z4I9_CHICK Computationally mapped isoform of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC416086 PE=3 SV=1 CANONICAL=A0A8V0Z4I9-1" }, "locus": { "chromosome": "12", "start_pos": 14840244, "end_pos": 14833073, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047540.1", "url": "https://www.ensembl.org/id/ENSGALT00010047540.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028148.1", "url": "https://www.ensembl.org/id/ENSGALP00010028148.1" } ] } }, { "isoform_ac": "A0A8V0ZB60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9/entry#A0A8V0ZB60-1", "sequence": { "sequence": "MTFSLGWFCLLLPYCSMEGSRNSLVFGSRKRASQGAPGARSRPVAMPPHSDAGPVAGPPDGGWGWVVVFGAFISIGFAYAFPKGIAIFYKEIQDFFDTSYSEIAWVSSIMLATTYGAGPISSILVNRYGSRPVVILGGLLCGIGMVSAAFCTSIIQLYICVGFITGLGLALNLQPSVIIIGRYFLKRRPIANGLAMAGSPVMLCTLAPLNQFLFDNYGWRGSFLILGAILLHCCVAGALFRPISADKASVKTQSIEEGKEVLKEEVTKDVIEMNSPTNVRMETKTEEEEERDCCEKVNKYLDFSLFKHRGFLIYLIGNVLMFLGFFAPIVFLAPYAKHIGIDEYSAAFLLSILAIVDMVARPTTGIIANSKWVRPRIQYFFSFSIAFNGTCHLLCPLASGYTGLVIYSVFFGLAFGMVCAMLFETLMDLVGASRFTSAVGLVTIAECCTILLGPPIGGTLIDTFGDYKYMFIKCGAVMVLAGTFLFIMNYYNYRMLAKEEKKRKAKEEDTKPVRTENEGRNNWNKEHVQDGPELEPLREEQEGLKKEANGTNEV", "length": 554, "header": "tr|A0A8V0ZB60-1|A0A8V0Z4I9_CHICK Computationally mapped isoform of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC416086 PE=3 SV=1 CANONICAL=A0A8V0Z4I9-1" }, "locus": { "chromosome": "12", "start_pos": 14840244, "end_pos": 14820876, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047553.1", "url": "https://www.ensembl.org/id/ENSGALT00010047553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028158.1", "url": "https://www.ensembl.org/id/ENSGALP00010028158.1" } ] } }, { "isoform_ac": "A0A8V0ZHU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9/entry#A0A8V0ZHU0-1", "sequence": { "sequence": "MPPHSDAGPVAGPPDGGWGWVVVFGAFISIGFAYAFPKGIAIFYKEIQDFFDTSYSEIAWVSSIMLATTYGPISSILVNRYGSRPVVILGGLLCGIGMVSAAFCTSIIQLYICVGFITGLGLALNLQPSVIIIGRYFLKRRPIANGLAMAGSPVMLCTLAPLNQFLFDNYGWRGSFLILGAILLHCCVAGALFRPISADKASVKTQSIEEGKEVLKEEVTKDVIEMNSPTNVRMETKTEEEEERDCCEKVNKYLDFSLFKHRGFLIYLIGNVLMFLGFFAPIVFLAPYAKHIGIDEYSAAFLLSILAIVDMVARPTTGIIANSKWVRPRIQYFFSFSIAFNGTCHLLCPLASGYTGLVIYSVFFGLAFGMVCAMLFETLMDLVGASRFTSAVGLVTIAECCTILLGPPIGGTLIDTFGDYKYMFIKCGAVMVLAGTFLFIMNYYNYRMLAKEEKKRKAKEEDTKPVRTENEGRNNWNKEHVQDGPELEPLREEQEGLKKEANGTNEV", "length": 507, "header": "tr|A0A8V0ZHU0-1|A0A8V0Z4I9_CHICK Computationally mapped isoform of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC416086 PE=3 SV=1 CANONICAL=A0A8V0Z4I9-1" }, "locus": { "chromosome": "12", "start_pos": 14840244, "end_pos": 14825151, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047544.1", "url": "https://www.ensembl.org/id/ENSGALT00010047544.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028150.1", "url": "https://www.ensembl.org/id/ENSGALP00010028150.1" } ] } }, { "isoform_ac": "A0A8V0ZHU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9/entry#A0A8V0ZHU9-1", "sequence": { "sequence": "MSPPLTSDLGYVPPDGGWGWAVVFGASISVGFSYTFPKAFTIYFKELQAVFSISYSQLAWITSIMCATTYGGGPISSILVNRYGSRPVVILGGLLCGIGMVSAAFCTSIIQLYICVGFITGLGLALNLQPSVIIIGRYFLKRRPIANGLAMAGSPVMLCTLAPLNQFLFDNYGWRGSFLILGAILLHCCVAGALFRPISADKASVKTQSIEEGKEVLKEEVTKDVIEMNSPTNVRMETKTEEEEERDCCEKVNKYLDFSLFKHRGFLIYLIGNVLMFLGFFAPIVFLAPYAKHIGIDEYSAAFLLSILAIVDMVARPTTGIIANSKWVRPRIQYFFSFSIAFNGTCHLLCPLASGYTGLVIYSVFFGLAFGMVCAMLFETLMDLVGASRFTSAVGLVTIAECCTILLGPPIGGTLIDTFGDYKYMFIKCGAVMVLAGTFLFIMNYYNYRMLAKEEKKRKAKEEDTKPVRTENEGRNNWNKEHVQDGPELEPLREEQEGLKKEANGTNEV", "length": 509, "header": "tr|A0A8V0ZHU9-1|A0A8V0Z4I9_CHICK Computationally mapped isoform of Major facilitator superfamily (MFS) profile domain-containing protein OS=Gallus gallus OX=9031 GN=LOC416086 PE=3 SV=1 CANONICAL=A0A8V0Z4I9-1" }, "locus": { "chromosome": "12", "start_pos": 14840244, "end_pos": 14818664, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047556.1", "url": "https://www.ensembl.org/id/ENSGALT00010047556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028160.1", "url": "https://www.ensembl.org/id/ENSGALP00010028160.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416086", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416086", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 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"output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71779", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71779" } ] }, { "id": "71783", "name": "", "equation": "3-methyl-2-oxobutanoate(out) + H(+)(out) = 3-methyl-2-oxobutanoate(in) + H(+)(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "71783", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/71783" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I9" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 19, 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3M5-1", "uniprot_ac": "A0A8V0Z3M5", "uniprot_id": "A0A8V0Z3M5_CHICK", "mass": { "chemical_mass": 130623.0, "monoisotopic_mass": 130623.0 }, "refseq": { "ac": "XP_004940615", "name": "fibronectin type-III domain-containing protein 3a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940615" }, "gene_names": [ { "name": "LOC422151", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M5" } ] }, { "name": "LOC422151", "type": "synonym", "evidence": [ { "id": "XP_004940615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940615" } ] } ], "protein_names": [ { "name": "Fibronectin type-III domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M5/entry#names_and_taxonomy" } ] }, { "name": "fibronectin type-III domain-containing protein 3a", "type": "synonym", "evidence": [ { "id": "XP_004940615", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940615" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004940615.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004940615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940615" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3M5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC422151", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M5", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z3M5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3M5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "422151", "url": "https://www.ncbi.nlm.nih.gov/gene/422151", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422151", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422151", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EWGQTEG", "url": "https://omabrowser.org/oma/group/EWGQTEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3M5", "url": "https://www.orthodb.org/?gene=A0A8V0Z3M5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4Q8", "url": "https://www.orthodb.org/?gene=A0A8V0Z4Q8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAK4", "url": "https://www.orthodb.org/?gene=A0A8V0ZAK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24099:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24099:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004940615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004940615", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3M5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAK4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMADQPPPLEATPLLNEVPLLPHMVNGDSIQQVILVQVNPGETFTITTEDGHIQCIQGPAHVPMMSPNGSMPPIFVPPGYVSQVVEENGVRKVVVLPHSAEFHPSMHPPPHPPPHVPHYMHHHHALLPHPPHPVYPPVPGTGELPPQFIHQHPPPHVFQEQEPRSHGRTNFIQRDERSLKMQEHLKKRLKDRQASGHTNNKLNSPPSSPHKVNNSSSAAVQNGNGKGQQGTGGPLKQKQIGKTKGSPDAEMGESDTESKKCDTHLSIGKPVVSDIQARSAVLSWNLPVSSQNGESHSHSPAAFTFEVAISNSGKSGKFKSVYVGEELTITLPDLRPATDYHARVSATSSSIKESVSELVSFTTESCEPDCPAAPKLINRTKNSLSLQWKSSNDNGSKITNFLLEWDEGKNGPFKECYYGHLKQYKLTKLSPSTKYSLRLAAKNDIGMSGFSETVTYYTAGMVPPAPPPPVLVEAGVTWLALQWSPPSGVSSEDSLTYTLDMEEEGSGYGFQPQYNGDELSCTLRNLRRSTFYKFRLFAYNSEGKSSPSEVVEHSTNPDKPGPPSKPTAKGKIHSHSVKVAWEPPKDNGGSDIAKYFLEISEAGIGSKWDTIYSGSQREHVCDHLKPGTSYRMRVHCVSRGGESQASDILTVTTSAVPPGPCPPPCLAGKAKPKEITLQWGPPLVDGGSDITEYIIEMANSEQEERRQVYQGAAPECTVCNLLPGRMYCFWLRAANRVGFGPHSDKAEICTAPGPPDQCCKPTITCKNAACVAVSWESPACNGAEISEYRLEWGQVEGSMHVIYTGPCQSYEVKGLTPATTYYCRVQAVNIAGVGLFGETGVVTTPASVPAAVSVLQLLEEDQMEVPLPLSTCLAIQWEEPCCHGAEITGYNIEYGEKQLVTVGRNTSHILENLLPDTLYRVRIQAINSFGVGPFSHSIKAKTKPLPPDPPHLECVVFSYQSLKLKWGEGPSRALITNPTQFNLQMEDRFGRFVTVYSGPCHTYKVQRLSESTTYYFKIQAYNDAGEGEFSDVYAFTTTKSPPASLKAPKANQLEENTYEITWEPLQPMKGDSIVYILQLAAGREFDQVYKGPETSFRLTGLQTNCEYRIRVCAGRQSQDAAGSQELYGPYSPSAVFSSQKQELEPQCAAVPPELADSKKTLHEERFIAIVLLCGFAVVAILFAVVIQYFVIK", "length": 1192, "header": "tr|A0A8V0Z3M5-1|A0A8V0Z3M5_CHICK Isoform 1 of Fibronectin type-III domain-containing protein OS=Gallus gallus OX=9031 GN=LOC422151 PE=1 SV=1 CANONICAL=A0A8V0Z3M5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M5/entry#A0A8V0Z3M5-1", "sequence": { "sequence": "MMADQPPPLEATPLLNEVPLLPHMVNGDSIQQVILVQVNPGETFTITTEDGHIQCIQGPAHVPMMSPNGSMPPIFVPPGYVSQVVEENGVRKVVVLPHSAEFHPSMHPPPHPPPHVPHYMHHHHALLPHPPHPVYPPVPGTGELPPQFIHQHPPPHVFQEQEPRSHGRTNFIQRDERSLKMQEHLKKRLKDRQASGHTNNKLNSPPSSPHKVNNSSSAAVQNGNGKGQQGTGGPLKQKQIGKTKGSPDAEMGESDTESKKCDTHLSIGKPVVSDIQARSAVLSWNLPVSSQNGESHSHSPAAFTFEVAISNSGKSGKFKSVYVGEELTITLPDLRPATDYHARVSATSSSIKESVSELVSFTTESCEPDCPAAPKLINRTKNSLSLQWKSSNDNGSKITNFLLEWDEGKNGPFKECYYGHLKQYKLTKLSPSTKYSLRLAAKNDIGMSGFSETVTYYTAGMVPPAPPPPVLVEAGVTWLALQWSPPSGVSSEDSLTYTLDMEEEGSGYGFQPQYNGDELSCTLRNLRRSTFYKFRLFAYNSEGKSSPSEVVEHSTNPDKPGPPSKPTAKGKIHSHSVKVAWEPPKDNGGSDIAKYFLEISEAGIGSKWDTIYSGSQREHVCDHLKPGTSYRMRVHCVSRGGESQASDILTVTTSAVPPGPCPPPCLAGKAKPKEITLQWGPPLVDGGSDITEYIIEMANSEQEERRQVYQGAAPECTVCNLLPGRMYCFWLRAANRVGFGPHSDKAEICTAPGPPDQCCKPTITCKNAACVAVSWESPACNGAEISEYRLEWGQVEGSMHVIYTGPCQSYEVKGLTPATTYYCRVQAVNIAGVGLFGETGVVTTPASVPAAVSVLQLLEEDQMEVPLPLSTCLAIQWEEPCCHGAEITGYNIEYGEKQLVTVGRNTSHILENLLPDTLYRVRIQAINSFGVGPFSHSIKAKTKPLPPDPPHLECVVFSYQSLKLKWGEGPSRALITNPTQFNLQMEDRFGRFVTVYSGPCHTYKVQRLSESTTYYFKIQAYNDAGEGEFSDVYAFTTTKSPPASLKAPKANQLEENTYEITWEPLQPMKGDSIVYILQLAAGREFDQVYKGPETSFRLTGLQTNCEYRIRVCAGRQSQDAAGSQELYGPYSPSAVFSSQKQELEPQCAAVPPELADSKKTLHEERFIAIVLLCGFAVVAILFAVVIQYFVIK", "length": 1192, "header": "tr|A0A8V0Z3M5-1|A0A8V0Z3M5_CHICK Isoform 1 of Fibronectin type-III domain-containing protein OS=Gallus gallus OX=9031 GN=LOC422151 PE=1 SV=1 CANONICAL=A0A8V0Z3M5-1" }, "locus": { "chromosome": "4", "start_pos": 1275919, "end_pos": 1253543, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043021.1", "url": "https://www.ensembl.org/id/ENSGALT00010043021.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025511.1", "url": "https://www.ensembl.org/id/ENSGALP00010025511.1" } ] } }, { "isoform_ac": "A0A8V0Z4Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M5/entry#A0A8V0Z4Q8-1", "sequence": { "sequence": "MGTASNRCCAHVQKQPTYPEQNCFLSCELTGVILVQVNPGETFTITTEDGHIQCIQGPAHVPMMSPNGSMPPIFVPPGYVSQVVEENGVRKVVVLPHSAEFHPSMHPPPHPPPHVPHYMHHHHALLPHPPHPVYPPVPGTGELPPQFIHQHPPPHVFQEQEPRSHGRTNFIQRDERSLKMQEHLKKRLKDRQASGHTNNKLNSPPSSPHKVNNSSSAAVQNGNGKGQQGTGGPLKQKQIGKTKGSPDAEMGESDTESKKCDTHLSIGKPVVSDIQARSAVLSWNLPVSSQNGESHSHSPAAFTFEVAISNSGKSGKFKSVYVGEELTITLPDLRPATDYHARVSATSSSIKESVSELVSFTTESCEPDCPAAPKLINRTKNSLSLQWKSSNDNGSKITNFLLEWDEGKNGPFKECYYGHLKQYKLTKLSPSTKYSLRLAAKNDIGMSGFSETVTYYTAGMVPPAPPPPVLVEAGVTWLALQWSPPSGVSSEDSLTYTLDMEEEGSGYGFQPQYNGDELSCTLRNLRRSTFYKFRLFAYNSEGKSSPSEVVEHSTNPDKPGPPSKPTAKGKIHSHSVKVAWEPPKDNGGSDIAKYFLEISEAGIGSKWDTIYSGSQREHVCDHLKPGTSYRMRVHCVSRGGESQASDILTVTTSAVPPGPCPPPCLAGKAKPKEITLQWGPPLVDGGSDITEYIIEMANSEQEERRQVYQGAAPECTVCNLLPGRMYCFWLRAANRVGFGPHSDKAEICTAPGPPDQCCKPTITCKNAACVAVSWESPACNGAEISEYRLEWGQVEGSMHVIYTGPCQSYEVKGLTPATTYYCRVQAVNIAGVGLFGETGVVTTPASVPAAVSVLQLLEEDQMEVPLPLSTCLAIQWEEPCCHGAEITGYNIEYGEKQLVTVGRNTSHILENLLPDTLYRVRIQAINSFGVGPFSHSIKAKTKPLPPDPPHLECVVFSYQSLKLKWGEGPSRALITNPTQFNLQMEDRFGRFVTVYSGPCHTYKVQRLSESTTYYFKIQAYNDAGEGEFSDVYAFTTTKSPPASLKAPKANQLEENTYEITWEPLQPMKGDSIVYILQLAAGREFDQVYKGPETSFRLTGLQTNCEYRIRVCAGRQSQDAAGSQELYGPYSPSAVFSSQKQELEPQCAAVPPELADSKKTLHEERFIAIVLLCGFAVVAILFAVVIQYFVIK", "length": 1191, "header": "tr|A0A8V0Z4Q8-1|A0A8V0Z4Q8_CHICK Computationally mapped isoform of Fibronectin type-III domain-containing protein OS=Gallus gallus OX=9031 GN=LOC422151 PE=1 SV=1 CANONICAL=A0A8V0Z3M5-1" }, "locus": { "chromosome": "4", "start_pos": 1275843, "end_pos": 1253543, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043016.1", "url": "https://www.ensembl.org/id/ENSGALT00010043016.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025505.1", "url": "https://www.ensembl.org/id/ENSGALP00010025505.1" } ] } }, { "isoform_ac": "A0A8V0ZAK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M5/entry#A0A8V0ZAK4-1", "sequence": { "sequence": "MDTFSVFKVVEENGVRKVVVLPHSAEFHPSMHPPPHPPPHVPHYMHHHHALLPHPPHPVYPPVPGTGELPPQFIHQHPPPHVFQEQEPRSHGRTNFIQRDERSLKMQEHLKKRLKDRQASGHTNNKLNSPPSSPHKVNNSSSAAVQNGNGKGQQGTGGPLKQKQIGKTKGSPDAEMGESDTESKKCDTHLSIGKPVVSDIQARSAVLSWNLPVSSQNGESHSHSPAAFTFEVAISNSGKSGKFKSVYVGEELTITLPDLRPATDYHARVSATSSSIKESVSELVSFTTESCEPDCPAAPKLINRTKNSLSLQWKSSNDNGSKITNFLLEWDEGKNGPFKECYYGHLKQYKLTKLSPSTKYSLRLAAKNDIGMSGFSETVTYYTAGMVPPAPPPPVLVEAGVTWLALQWSPPSGVSSEDSLTYTLDMEEEGSGYGFQPQYNGDELSCTLRNLRRSTFYKFRLFAYNSEGKSSPSEVVEHSTNPDKPGPPSKPTAKGKIHSHSVKVAWEPPKDNGGSDIAKYFLEISEAGIGSKWDTIYSGSQREHVCDHLKPGTSYRMRVHCVSRGGESQASDILTVTTSAVPPGPCPPPCLAGKAKPKEITLQWGPPLVDGGSDITEYIIEMANSEQEERRQVYQGAAPECTVCNLLPGRMYCFWLRAANRVGFGPHSDKAEICTAPGPPDQCCKPTITCKNAACVAVSWESPACNGAEISEYRLEWGQVEGSMHVIYTGPCQSYEVKGLTPATTYYCRVQAVNIAGVGLFGETGVVTTPASVPAAVSVLQLLEEDQMEVPLPLSTCLAIQWEEPCCHGAEITGYNIEYGEKQLVTVGRNTSHILENLLPDTLYRVRIQAINSFGVGPFSHSIKAKTKPLPPDPPHLECVVFSYQSLKLKWGEGPSRALITNPTQFNLQMEDRFGRFVTVYSGPCHTYKVQRLSESTTYYFKIQAYNDAGEGEFSDVYAFTTTKSPPASLKAPKANQLEENTYEITWEPLQPMKGDSIVYILQLAAGREFDQVYKGPETSFRLTGLQTNCEYRIRVCAGRQSQDAAGSQELYGPYSPSAVFSSQKQELEPQCAAVPPELADSKKTLHEERFIAIVLLCGFAVVAILFAVVIQYFVIK", "length": 1117, "header": "tr|A0A8V0ZAK4-1|A0A8V0Z3M5_CHICK Computationally mapped isoform of Fibronectin type-III domain-containing protein OS=Gallus gallus OX=9031 GN=LOC422151 PE=1 SV=1 CANONICAL=A0A8V0Z3M5-1" }, "locus": { "chromosome": "4", "start_pos": 1272242, "end_pos": 1253543, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043013.1", "url": "https://www.ensembl.org/id/ENSGALT00010043013.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025503.1", "url": "https://www.ensembl.org/id/ENSGALP00010025503.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422151", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422151", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3M5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3M5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 905, "end_pos": 907, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3M5", "database": "UniProtKB", "url": 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"A0A8V0Z592-1", "uniprot_ac": "A0A8V0Z592", "uniprot_id": "A0A8V0Z592_CHICK", "mass": { "chemical_mass": 27951.0, "monoisotopic_mass": 27951.0 }, "refseq": { "ac": "NP_001026383", "name": "cell division cycle-associated protein 4 isoform a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026383" }, "gene_names": [ { "name": "CDCA4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592" } ] }, { "name": "CDCA4", "type": "synonym", "evidence": [ { "id": "NP_001026383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026383" } ] } ], "protein_names": [ { "name": "Cell division cycle associated 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z592", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592/entry#names_and_taxonomy" } ] }, { "name": "cell division cycle-associated protein 4 isoform a", "type": "synonym", "evidence": [ { "id": 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The reference sequence was derived from JAENSK010000215.1. On Nov 24, 2021 this sequence version replaced NP_001026383.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001026383", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001026383" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z592", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDCA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592", "locus": { "chromosome": "5", "start_pos": 51455850, "end_pos": 51467270, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016885", "url": "https://www.ensembl.org/id/ENSGALG00010016885" } ] } } ], "crossref": [ { "id": "ENSGALG00000011692", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000011692", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423500", "url": "https://www.ncbi.nlm.nih.gov/gene/423500", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052262", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052262", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423500", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423500", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q3AAV9", "url": "https://www.orthodb.org/?gene=A0A3Q3AAV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YYJ0", "url": "https://www.orthodb.org/?gene=A0A8V0YYJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z592", "url": "https://www.orthodb.org/?gene=A0A8V0Z592", "database": 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"MFMRGLKRKCFDGEEDIEGTLAGIKAIPSYNLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMTQDGTWQMINMQNTGQASVDRLVSTDILCRSSREQAEGKHVPGYSTFSKDFEGDQAQDSSETMSTASSVQALRNLQSNVWEMENSQENKGNFQKSLDQIFETLENKSPNSVEDLFSEVDNSYYDLDTMLTGMMSNTKMGHCDGLEPFPSPTTTTSSSNCKSDLNELDHIVEILVES", "length": 249, "header": "tr|A0A8V0Z592-1|A0A8V0Z592_CHICK Isoform 1 of Cell division cycle associated 4 OS=Gallus gallus OX=9031 GN=CDCA4 PE=4 SV=1 CANONICAL=A0A8V0Z592-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AAV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592/entry#A0A3Q3AAV9-1", "sequence": { "sequence": "MPVETQEERGETASPVGEIQLLRWSLLCEAAAPDFHQVWHLMGTRSWEPLPLSGASLRSHDSWTCSLLVPECRLWDPVHVFLTPVVPQWPFYNLDTMFMRGLKRKCFDGEEDIEGTLAGIKAIPSYNLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMTQDGTWQMINMQNTGQASVDRLVSTDILCRSSREQAEGKHVPGYSTFSKDFEGDQAQDSSETMSTASSVQALRNLQSNVWEMENSQENKGNFQKSLDQIFETLENKSPNSVEDLFSEVDNSYYDLDTMLTGMMSNTKMGHCDGLEPFPSPTTTTSSSNCKSDLNELDHIVEILVES", "length": 345, "header": "tr|A0A3Q3AAV9-1|A0A8V0Z592_CHICK Computationally mapped isoform of Cell division cycle associated 4 OS=Gallus gallus OX=9031 GN=CDCA4 PE=4 SV=1 CANONICAL=A0A8V0Z592-1" }, "locus": { "chromosome": "5", "start_pos": 51461754, "end_pos": 51460580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040760.1", "url": "https://www.ensembl.org/id/ENSGALT00010040760.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023724.1", "url": "https://www.ensembl.org/id/ENSGALP00010023724.1" } ] } }, { "isoform_ac": "A0A8V0YYJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592/entry#A0A8V0YYJ0-1", "sequence": { "sequence": "MPVETQEERGETASPVGEIQLLRWSLLSWEPLPLSGASLRSHDSWTCSLLVPECRLWDPVHVFLTPVVPQWPFYNLDTMFMRGLKRKCFDGEEDIEGTLAGIKAIPSYNLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMTQDGTWQMINMQNTGQASVDRLVSTDILCRSSREQAEGKHVPGYSTFSKDFEGDQAQDSSETMSTASSVQALRNLQSNVWEMENSQENKGNFQKSLDQIFETLENKSPNSVEDLFSEVDNSYYDLDTMLTGMMSNTKMGHCDGLEPFPSPTTTTSSSNCKSDLNELDHIVEILVES", "length": 327, "header": "tr|A0A8V0YYJ0-1|A0A8V0Z592_CHICK Computationally mapped isoform of Cell division cycle associated 4 OS=Gallus gallus OX=9031 GN=CDCA4 PE=4 SV=1 CANONICAL=A0A8V0Z592-1" }, "locus": { "chromosome": "5", "start_pos": 51461754, "end_pos": 51460580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040754.1", "url": "https://www.ensembl.org/id/ENSGALT00010040754.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023718.1", "url": "https://www.ensembl.org/id/ENSGALP00010023718.1" } ] } }, { "isoform_ac": "A0A8V0Z592-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592/entry#A0A8V0Z592-1", "sequence": { "sequence": "MFMRGLKRKCFDGEEDIEGTLAGIKAIPSYNLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMTQDGTWQMINMQNTGQASVDRLVSTDILCRSSREQAEGKHVPGYSTFSKDFEGDQAQDSSETMSTASSVQALRNLQSNVWEMENSQENKGNFQKSLDQIFETLENKSPNSVEDLFSEVDNSYYDLDTMLTGMMSNTKMGHCDGLEPFPSPTTTTSSSNCKSDLNELDHIVEILVES", "length": 249, "header": "tr|A0A8V0Z592-1|A0A8V0Z592_CHICK Isoform 1 of Cell division cycle associated 4 OS=Gallus gallus OX=9031 GN=CDCA4 PE=4 SV=1 CANONICAL=A0A8V0Z592-1" }, "locus": { "chromosome": "5", "start_pos": 51461326, "end_pos": 51460580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040732.1", "url": "https://www.ensembl.org/id/ENSGALT00010040732.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023697.1", "url": "https://www.ensembl.org/id/ENSGALP00010023697.1" } ] } }, { "isoform_ac": "F1NMS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592/entry#F1NMS9-1", "sequence": { "sequence": "MGEEEGLHQAQLLDTMFMRGLKRKCFDGEEDIEGTLAGIKAIPSYNLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQIQEEMTQDGTWQMINMQNTGQASVDRLVSTDILCRSSREQAEGKHVPGYSTFSKDFEGDQAQDSSETMSTASSVQALRNLQSNVWEMENSQENKGNFQKSLDQIFETLENKSPNSVEDLFSEVDNSYYDLDTMLTGMMSNTKMGHCDGLEPFPSPTTTTSSSNCKSDLNELDHIVEILVES", "length": 264, "header": "tr|F1NMS9-1|A0A8V0Z592_CHICK Computationally mapped isoform of Cell division cycle associated 4 OS=Gallus gallus OX=9031 GN=CDCA4 PE=4 SV=2 CANONICAL=A0A8V0Z592-1" }, "locus": { "chromosome": "5", "start_pos": 51463676, "end_pos": 51460580, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040740.1", "url": "https://www.ensembl.org/id/ENSGALT00010040740.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023705.1", "url": "https://www.ensembl.org/id/ENSGALP00010023705.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423500", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423500", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z592", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z592", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z592", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z592", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z592" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3B5-1", "uniprot_ac": "A0A8V0Z3B5", "uniprot_id": "A0A8V0Z3B5_CHICK", "mass": { "chemical_mass": 97252.0, "monoisotopic_mass": 97252.0 }, "refseq": {}, "gene_names": [ { "name": "BBS9", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ] } ], "protein_names": [ { "name": "Bardet-Biedl syndrome 9", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BBS9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5", "locus": { "chromosome": "2", "start_pos": 47600423, "end_pos": 47888924, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019256", "url": "https://www.ensembl.org/id/ENSGALG00010019256" } ] } } ], "crossref": [ { "id": "A0A8V0Z3B5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3B5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031650", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031650", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "420745", "url": "https://www.ncbi.nlm.nih.gov/gene/420745", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:420745", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420745", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q3AST7", "url": "https://www.orthodb.org/?gene=A0A3Q3AST7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3A4", "url": "https://www.orthodb.org/?gene=A0A8V0Z3A4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3A9", "url": "https://www.orthodb.org/?gene=A0A8V0Z3A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3B5", "url": "https://www.orthodb.org/?gene=A0A8V0Z3B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z957", "url": "https://www.orthodb.org/?gene=A0A8V0Z957", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z978", "url": "https://www.orthodb.org/?gene=A0A8V0Z978", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z983", "url": "https://www.orthodb.org/?gene=A0A8V0Z983", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9W9", "url": "https://www.orthodb.org/?gene=A0A8V0Z9W9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Y7", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Y7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAQ3", "url": "https://www.orthodb.org/?gene=A0A8V0ZAQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20991", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20991", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20991:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20991:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14728", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14728", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23337", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23338", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23338", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23339", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23339", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5620922", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620922", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3Q3AST7", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AST7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q3AST7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q3AST7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3A4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3A9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z957", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z957", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z957-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z957-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z978", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z978", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z978-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z978-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z983", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z983", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z983-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z983-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9W9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9W9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Y7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLFKARDWWSTVLGEKEEFDQGCLCVADVDNSGQDKIIVGSYMGYLRIFNPRPVKPGDGVQAEDLLLEVQLREPVLQVEVGKFVSGTEGLHLAVLHCRRLCVYAVSETLGNVDHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSMDGMLMLFEQESYAFGRFLPGFLLPGPLTYSSRTDSFITVSSSRQVESYKYQVLAFATDADGRQETVQQKLSSGKKLVVDWVLNIGEQALDICIVSFNQAVSSVFVLGERSLFCLKDNGQIRFMKKLDYSPSCFIPYCSVKEGTINTLVGNHSKMLYVYQDITLKWATQLPHVPVSVKVANLQGLKGVIVTLSDNGHLQCSYLGTDPSLFQAPRVESKEINYEEFNAEMKELQKIIKEATITQDILPQSEKHRDLIVTAEVSPDLDVESQAIDSEVKAEVVPSVTIKVTIQSKMTAQQPYLAVCIQAPLAVTCDRFTFNDLEPGSSETVVLSVFLKGNFPPSELEGNCVFSCNTPTGIPKVAQCKFKLPLRLVCFPAQPSKSANHKLTIDTNKPPISFLTIFPDFADPSEEDQANVLGFQFLTGSKITLLASKTSQRYRIQSDQLEDLWLITKELTLRLEEHFKKQNCKDFACTFSGSVPLQEYFELIDRHFELRLNAEKFQELLSERAIQFRAIERRLLTRFKDKTPAPLQHLDTLLEGTFREVIALADAAEENQANMFQAFTKLKSATHLVIMLISLWQKLNADQVAIMEATFLPLAEDTQELGWEETVDSAISFLLRTCLSKSSKEQALSLSSQLSMPKDTSRLKKNISLFCDRLAKGGRLSLSTEAATQQATVVPGGCATIPESDLEERAVVPGSTAVFSSHKHTAKQKSSPAT", "length": 872, "header": "tr|A0A8V0Z3B5-1|A0A8V0Z3B5_CHICK Isoform 1 of Bardet-Biedl syndrome 9 OS=Gallus gallus OX=9031 GN=BBS9 PE=1 SV=1 CANONICAL=A0A8V0Z3B5-1" }, "isoforms": [ { "isoform_ac": "A0A3Q3AST7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5/entry#A0A3Q3AST7-1", "sequence": { "sequence": "MSLFKARDWWSTVLGEKEEFDQGCLCVADVDNSGQDKIIVGSYMGYLRIFNPRPVKPGDGVQAEDLLLEVQLREPVLQVEVGKFVSGTEGLHLAVLHCRRLCVYAVSETLGNVDHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSMDGMLMLFEQESYAFGRFLPGFLLPGPLTYSSRTDSFITVSSSRQVESYKYQVLAFATDADGRQETVQQKLSSGKKLVVDWVLNIGEQALDICIVSFNQAVSSVFVLGERSLFCLKDNGQIRFMKKLDYSPSCFIPYCSVKEGTINTLVGNHSKMLYVYQDITLKWATQLPHVPVSVKVANLQGLKGVIVTLSDNGHLQCSYLGTDPSLFQAPRVESKEINYEEFNAEMKELQKIIKEATITQDILPQSEKHRDLIVTAEVSPDLDVESQAIDSEVKAEVVPSVTIKVTIQSKMTAQQPYLAVCIQAPLAVTCDRFTFNDLEPGSSETVVLSVFLKGNFPPSELEGNCVFSCNTPTDFADPSEEDQANVLGFQFLTGSKITLLASKTSQRYRIQSDQLEDLWLITKELTLRLEEHFKKQNCKDFACTFSGSVPLQEYFELIDRHFELRLNAEKFQELLSERAIQFRAIERRLLTRFKDKTPAPLQHLDTLLEGTFREVIALADAAEENQANMFQAFTKLKSATHLVIMLISLWQKLNADQVAIMEATFLPLAEDTQELGWEETVDSAISFLLRTCLSKSSKEQALSLSSQLSMPKDTSRLKKNISLFCDRLAKGGRLSLSTEAATQQATVVPGGCATIPESDLEERAVVPGSTAVFSSHKHTAKQKSSPGLSEDAAEEAEKP", "length": 836, "header": "tr|A0A3Q3AST7-1|A0A8V0Z3B5_CHICK Computationally mapped isoform of Bardet-Biedl syndrome 9 OS=Gallus gallus OX=9031 GN=BBS9 PE=1 SV=1 CANONICAL=A0A8V0Z3B5-1" }, "locus": { "chromosome": "2", "start_pos": 47887564, "end_pos": 47601427, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046585.1", "url": "https://www.ensembl.org/id/ENSGALT00010046585.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027743.1", "url": "https://www.ensembl.org/id/ENSGALP00010027743.1" } ] } }, { "isoform_ac": "A0A8V0Z3A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5/entry#A0A8V0Z3A4-1", "sequence": { "sequence": "MSLFKARDWWSTVLGEKEEFDQGCLCVADVDNSGQDKIIVGSYMGYLRIFNPRPVKPGDGVQAEDLLLEVQLREPVLQVEVGKFVSGTEGLHLAVLHCRRLCVYAVSETLGNVDHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSMDGMLMLFEQESYAFGRFLPGFLLPGPLTYSSRTDSFITVSSSRQVESYKYQVLAFATDADGRQETVQQKLSSGKKLVVDWVLNIGEQALDICIVSFNQAVSSVFVLGERSLFCLKDNGQIRFMKKLDYSPSCFIPYCSVKEGTINTLVGNHSKMLYVYQDITLKWATQLPHVPVSVKVANLQGLKGVIVTLSDNGHLQCSYLGTDPSLFQAPRVESKEINYEEFNAEMKELQKIIKEATITQDILPQSEKHRDLIVTAEVSPDLDVESQAIDSEVKAEVVPSVTIKVTIQSKMTAQQPYLAVCIQAPLAVTCDRFTFNDLEPGSSETVVLSVFLKGNFPPSELEGNCVFSCNTPTELNPEGIPKVAQCKFKLPLRLVCFPAQPSKSANHKLTIDTNKPPISFLTIFPDFADPSEEDQANVLGFQFLTGSKITLLASKTSQRYRIQSDQLEDLWLITKELTLRLEEHFKKQNCKDFACTFSGSVPLQEYFELIDRHFELRLNAEKFQELLSERAIQFRAIERRLLTRFKDKTPAPLQHLDTLLEGTFREVIALADAAEENQANMFQAFTKLKSATHLVIMLISLWQKLNADQVAIMEATFLPLAEDTQELGWEETVDSAISFLLRTCLSKSSKEQALSLSSQLSMPKDTSRLKKNISLFCDRLAKGGRLSLSTEAATQQATVVPGGCATIPESDLEERAVVPGSTAVFSSHKHTAKQKSSPGTARSGISRLMMREIPRDLLSLQVCKVPHNIFFR", "length": 909, "header": "tr|A0A8V0Z3A4-1|A0A8V0Z3A4_CHICK Computationally mapped isoform of Bardet-Biedl syndrome 9 OS=Gallus gallus OX=9031 GN=BBS9 PE=1 SV=1 CANONICAL=A0A8V0Z3B5-1" }, "locus": { "chromosome": "2", "start_pos": 47887564, "end_pos": 47697055, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046556.1", "url": "https://www.ensembl.org/id/ENSGALT00010046556.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027718.1", "url": "https://www.ensembl.org/id/ENSGALP00010027718.1" } ] } }, { "isoform_ac": "A0A8V0Z3A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5/entry#A0A8V0Z3A9-1", "sequence": { "sequence": "MSLFKARDWWSTVLGEKEEFDQGCLCVADVDNSGQDKIIVGSYMGYLRIFNPRPVKPGDGVQAEDLLLEVQLREPVLQVEVGKFVSGTEGLHLAVLHCRRLCVYAVSETLGNVDHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSMDGMLMLFEQESYAFGRFLPGFLLPGPLTYSSRTDSFITVSSSRQVESYKYQVLAFATDADGRQETVQQKLSSGKKLVVDWVLNIGEQALDICIVSFNQAVSSVFVLGERSLFCLKDNGQIRFMKKLDYSPSCFIPYCSVKEGTINTLVGNHSKMLYVYQDITLKWATQLPHVPVSVKVANLQGLKGVIVTLSDNGHLQCSYLGTDPSLFQAPRVESKEINYEEFNAEMKELQKIIKEATITQDILPQSEKHRDLIVTAEVSPDLDVESQAIDSEVKAEVVPSVTIKVTIQSKMTAQQPYLAVCIQAPLAVTCDRFTFNDLEPGSSETVVLSVFLKGNFPPSELEGNCVFSCNTPTGIPKVAQCKFKLPLRLVCFPAQPSKSANHKLTIDTNKPPISFLTIFPDFADPSEEDQANVLGFQFLTGSKITLLASKTSQRYRIQSDQLEDLWLITKELTLRLEEHFKKQNCKDFACTFSGSVPLQEYFELIDRHFELRLNAEKFQELLSERAIQFRAIERRLLTRFKDKTPAPLQHLDTLLEGTFREVIALADAAEENQANMFQAFTKLKSATHLVIMLISLWQKLNADQVAIMEATFLPLAEDTQELGWEETVDSAISFLLRTCLSKSSKEQALSLSSQLSMPKDTSRLKKNISLFCDRLAKGGRLSLSTEAATQQATVVPGGCATIPESDLEERAVVPGSTAVFSSHKHTAKQKSSPVPGMCCVTSGAGQPEAWS", "length": 888, "header": "tr|A0A8V0Z3A9-1|A0A8V0Z3A9_CHICK Computationally mapped isoform of Bardet-Biedl syndrome 9 OS=Gallus gallus OX=9031 GN=BBS9 PE=1 SV=1 CANONICAL=A0A8V0Z3B5-1" }, "locus": { "chromosome": "2", "start_pos": 47887564, "end_pos": 47688842, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046562.1", "url": "https://www.ensembl.org/id/ENSGALT00010046562.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027723.1", "url": "https://www.ensembl.org/id/ENSGALP00010027723.1" } ] } }, { "isoform_ac": "A0A8V0Z3B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5/entry#A0A8V0Z3B5-1", "sequence": { "sequence": "MSLFKARDWWSTVLGEKEEFDQGCLCVADVDNSGQDKIIVGSYMGYLRIFNPRPVKPGDGVQAEDLLLEVQLREPVLQVEVGKFVSGTEGLHLAVLHCRRLCVYAVSETLGNVDHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSMDGMLMLFEQESYAFGRFLPGFLLPGPLTYSSRTDSFITVSSSRQVESYKYQVLAFATDADGRQETVQQKLSSGKKLVVDWVLNIGEQALDICIVSFNQAVSSVFVLGERSLFCLKDNGQIRFMKKLDYSPSCFIPYCSVKEGTINTLVGNHSKMLYVYQDITLKWATQLPHVPVSVKVANLQGLKGVIVTLSDNGHLQCSYLGTDPSLFQAPRVESKEINYEEFNAEMKELQKIIKEATITQDILPQSEKHRDLIVTAEVSPDLDVESQAIDSEVKAEVVPSVTIKVTIQSKMTAQQPYLAVCIQAPLAVTCDRFTFNDLEPGSSETVVLSVFLKGNFPPSELEGNCVFSCNTPTGIPKVAQCKFKLPLRLVCFPAQPSKSANHKLTIDTNKPPISFLTIFPDFADPSEEDQANVLGFQFLTGSKITLLASKTSQRYRIQSDQLEDLWLITKELTLRLEEHFKKQNCKDFACTFSGSVPLQEYFELIDRHFELRLNAEKFQELLSERAIQFRAIERRLLTRFKDKTPAPLQHLDTLLEGTFREVIALADAAEENQANMFQAFTKLKSATHLVIMLISLWQKLNADQVAIMEATFLPLAEDTQELGWEETVDSAISFLLRTCLSKSSKEQALSLSSQLSMPKDTSRLKKNISLFCDRLAKGGRLSLSTEAATQQATVVPGGCATIPESDLEERAVVPGSTAVFSSHKHTAKQKSSPAT", "length": 872, "header": "tr|A0A8V0Z3B5-1|A0A8V0Z3B5_CHICK Isoform 1 of Bardet-Biedl syndrome 9 OS=Gallus gallus OX=9031 GN=BBS9 PE=1 SV=1 CANONICAL=A0A8V0Z3B5-1" }, "locus": { "chromosome": "2", "start_pos": 47887564, "end_pos": 47642773, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046569.1", "url": "https://www.ensembl.org/id/ENSGALT00010046569.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027728.1", "url": "https://www.ensembl.org/id/ENSGALP00010027728.1" } ] } }, { "isoform_ac": "A0A8V0Z957-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5/entry#A0A8V0Z957-1", "sequence": { "sequence": "MSLFKARDWWSTVLGEKEEFDQGCLCVADVDNSGQDKIIVGSYMGYLRIFNPRPVKPGDGVQAEDLLLEVQLREPVLQVEVGKFVSGTEGLHLAVLHCRRLCVYAVSETLGNVDHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSMDGMLMLFEQESYAFGRFLPGFLLPGPLTYSSRTDSFITVSSSRQVESYKYQVLAFATDADGRQETVQQKLSSGKKLVVDWVLNIGEQALDICIVSFNQAVSSVFVLGERSLFCLKDNGQIRFMKKLDYSPSCFIPYCSVKEGTINTLVGNHSKMLYVYQDITLKWATQLPHVPVSVKVANLQGLKGVIVTLSDNGHLQCSYLGTDPSLFQAPRVESKEINYEEFNAEMKELQKIIKEATITQDILPQSEKHRDLIVTAEVSPDLDVESQAIDSEVKAEVVPSVTIKVTIQSKMTAQQPYLAVCIQAPLAVTCDRFTFNDLEPGSSETVVLSVFLKGNFPPSELEGNCVFSCNTPTGIPKVAQCKFKLPLRLVCFPAQPSKSANHKLTIDTNKPPISFLTIFPDFADPSEEDQANVLGFQFLTGSKITLLASKTSQRYRIQSDQLEDLWLITKELTLRLEEHFKKQNCKDFACTFSGSVPLQEYFELIDRHFELRLNAEKFQELLSERAIQFRAIERRLLTRFKDKTPAPLQHLDTLLEGTFREVIALADAAEENQANMFQAFTKLKSATHLVIMLISLWQKLNADQVAIMEATFLPLAEDTQELGWEETVDSAISFLLRTCLSKSSKEQALSLSSQLSMPKDTSRLKKNISLFCDRLAKGGRLSLSTEAATQQATVVPGGCATIPESDLEERAVVPGSTAVFSSHKHTAKQKSSPEIIFGKKCFFQGHSALDVCLISKAFSQKNDVSSAQR", "length": 906, "header": "tr|A0A8V0Z957-1|A0A8V0Z3B5_CHICK Computationally mapped isoform of Bardet-Biedl syndrome 9 OS=Gallus gallus OX=9031 GN=BBS9 PE=1 SV=1 CANONICAL=A0A8V0Z3B5-1" }, "locus": { "chromosome": "2", "start_pos": 47887564, "end_pos": 47690682, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046559.1", "url": "https://www.ensembl.org/id/ENSGALT00010046559.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027720.1", "url": "https://www.ensembl.org/id/ENSGALP00010027720.1" } ] } }, { "isoform_ac": "A0A8V0Z978-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5/entry#A0A8V0Z978-1", "sequence": { "sequence": "MSLFKARDWWSTVLGEKEEFDQGCLCVADVDNSGQDKIIVGSYMGYLRIFNPRPVKPGDGVQAEDLLLEVQLREPVLQVEVGKFVSGTEGLHLAVLHCRRLCVYAVSETLGNVDHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSMDGMLMLFEQESYAFGRFLPGFLLPGPLTYSSRTDSFITVSSSRQVESYKYQVLAFATDADGRQETVQQKLSSGKKLVVDWVLNIGEQALDICIVSFNQAVSSVFVLGERSLFCLKDNGQIRFMKKLDYSPSCFIPYCSVKEGTINTLVGNHSKMLYVYQDITLKWATQLPHVPVSVKVANLQGLKGVIVTLSDNGHLQCSYLGTDPSLFQAPRVESKEINYEEFNAEMKELQKIIKEATITQDILPQSEKHRDLIVTAEVSPDLDVESQAIDSEVKAEVVPSVTIKVTIQSKMTAQQPYLAVCIQAPLAVTCDRFTFNDLEPGSSETVVLSVFLKGNFPPSELEGNCVFSCNTPTELNPEGIPKVAQCKFKLPLRLVCFPAQPSKSANHKLTIDTNKPPISFLTIFPDFADPSEEDQANVLGFQFLTGSKITLLASKTSQRYRIQSDQLEDLWLITKELTLRLEEHFKKQNCKDFACTFSGSVPLQEYFELIDRHFELRLNAEKFQELLSERAIQFRAIERRLLTRFKDKTPAPLQHLDTLLEGTFREVIALADAAEENQANMFQAFTKLKSATHLVIMLISLWQKLNADQVAIMEATFLPLAEDTQELGWEETVDSAISFLLRTCLSKSSKEQALSLSSQLSMPKDTSRLKKNISLFCDRLAKGGRLSLSTEAATQQATVVPGGCATIPESDLEERAVVPGSTAVFSSHKHTAKQKSSPGLSEDAAEEAEKP", "length": 888, "header": "tr|A0A8V0Z978-1|A0A8V0Z3B5_CHICK Computationally mapped isoform of Bardet-Biedl syndrome 9 OS=Gallus gallus OX=9031 GN=BBS9 PE=1 SV=1 CANONICAL=A0A8V0Z3B5-1" }, "locus": { "chromosome": "2", "start_pos": 47887564, "end_pos": 47601427, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046582.1", "url": "https://www.ensembl.org/id/ENSGALT00010046582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027740.1", "url": "https://www.ensembl.org/id/ENSGALP00010027740.1" } ] } }, { "isoform_ac": "A0A8V0Z983-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5/entry#A0A8V0Z983-1", "sequence": { "sequence": "MSLFKARDWWSTVLGEKEEFDQGCLCVADVDNSGQDKIIVGSYMGYLRIFNPRPVKPGDGVQAEDLLLEVQLREPVLQVEVGKFVSGTEGLHLAVLHCRRLCVYAVSETLGNVDHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSMDGMLMLFEQESYAFGRFLPGFLLPGPLTYSSRTDSFITVSSSRQVESYKYQVLAFATDADGRQETVQQKLSSGKKLVVDWVLNIGEQALDICIVSFNQAVSSVFVLGERSLFCLKDNGQIRFMKKLDYSPSCFIPYCSVKEGTINTLVGNHSKMLYVYQDITLKWATQLPHVPVSVKVANLQGLKGVIVTLSDNGHLQCSYLGTDPSLFQAPRVESKEINYEEFNAEMKELQKIIKEATITQDILPQSEKHRDLIVTAEVSPDLDVESQAIDSEVKAEVVPSVTIKVTIQSKMTAQQPYLAVCIQAPLAVTCDRFTFNDLEPGSSETVVLSVFLKGNFPPSELEGNCVFSCNTPTGIPKVAQCKFKLPLRLVCFPAQPSKSANHKLTIDTNKPPISFLTIFPDFADPSEEDQANVLGFQFLTGSKITLLASKTSQRYRIQSDQLEDLWLITKELTLRLEEHFKKQNCKDFACTFSGSVPLQEYFELIDRHFELRLNAEKFQELLSERAIQFRAIERRLLTRFKDKTPAPLQHLDTLLEGTFREVIALADAAEENQANMFQAFTKLKSATHLVIMLISLWQKLNADQVAIMEATFLPLAEDTQELGWEETVDSAISFLLRTCLSKSSKEQALSLSSQLSMPKDTSRLKKNISLFCDRLAKGGRLSLSTEAATQQATVVPGLSEDAAEEAEKP", "length": 846, "header": "tr|A0A8V0Z983-1|A0A8V0Z3B5_CHICK Computationally mapped isoform of Bardet-Biedl syndrome 9 OS=Gallus gallus OX=9031 GN=BBS9 PE=1 SV=1 CANONICAL=A0A8V0Z3B5-1" }, "locus": { "chromosome": "2", "start_pos": 47887564, "end_pos": 47601427, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046587.1", "url": "https://www.ensembl.org/id/ENSGALT00010046587.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027745.1", "url": "https://www.ensembl.org/id/ENSGALP00010027745.1" } ] } }, { "isoform_ac": "A0A8V0Z9W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5/entry#A0A8V0Z9W9-1", "sequence": { "sequence": "MSLFKARDWWSTVLGEKEEFDQGCLCVADVDNSGQDKIIVGSYMGYLRIFNPRPVKPGDGVQAEDLLLEVQLREPVLQVEVGKFVSGTEGLHLAVLHCRRLCVYAVSETLGNVDHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSMDGMLMLFEQESYAFGRFLPGFLLPGPLTYSSRTDSFITVSSSRQVESYKYQVLAFATDADGRQETVQQKLSSGKKLVVDWVLNIGEQALDICIVSFNQAVSSVFVLGERSLFCLKDNGQIRFMKKLDYSPSCFIPYCSVKEGTINTLVGNHSKMLYVYQDITLKWATQLPHVPVSVKVANLQGLKGVIVTLSDNGHLQCSYLGTDPSLFQAPRVESKEINYEEFNAEMKELQKIIKEATITQDILPQSEKHRDLIVTAEVSPDLDVESQAIDSEVKAEVVPSVTIKVTIQSKMTAQQPYLAVCIQAPLAVTCDRFTFNDLEPGSSETVVLSVFLKGNFPPSELEGNCVFSCNTPTGIPKVAQCKFKLPLRLVCFPAQPSKSANHKLTIDTNKPPISFLTIFPDFADPSEEDQANVLGFQFLTGSKITLLASKTSQRYRIQSDQLEDLWLITKELTLRLEEHFKKQNCKDFACTFSGSVPLQEYFELIDRHFELRLNAEKFQELLSERAIQFRAIERRLLTRFKDKTPAPLQHLDTLLEGTFREVIALADAAEENQANMFQAFTKLKSATHLVIMLISLWQKLNADQVAIMEATFLPLAEDTQELGWEETVDSAISFLLRTCLSKSSKEQALSLSSQLSMPKDTSRLKKNISLFCDRLAKGGRLSLSTEAATQQATVVPGGCATIPESDLEERAVVPGSTAVFSSHKHTAKQKSSPGKKRKITLFCPEIHSLSFQSACRSVKQMTYISGFVSVIFRFSV", "length": 913, "header": "tr|A0A8V0Z9W9-1|A0A8V0Z3B5_CHICK Computationally mapped isoform of Bardet-Biedl syndrome 9 OS=Gallus gallus OX=9031 GN=BBS9 PE=1 SV=1 CANONICAL=A0A8V0Z3B5-1" }, "locus": { "chromosome": "2", "start_pos": 47887564, "end_pos": 47715805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046553.1", "url": "https://www.ensembl.org/id/ENSGALT00010046553.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027717.1", "url": "https://www.ensembl.org/id/ENSGALP00010027717.1" } ] } }, { "isoform_ac": "A0A8V0Z9Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5/entry#A0A8V0Z9Y7-1", "sequence": { "sequence": "MSLFKARDWWSTVLGEKEEFDQGCLCVADVDNSGQDKIIVGSYMGYLRIFNPRPVKPGDGVQAEDLLLEVQLREPVLQVEVGKFVSGTEGLHLAVLHCRRLCVYAVSETLGNVDHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSMDGMLMLFEQESYAFGRFLPGFLLPGPLTYSSRTDSFITVSSSRQVESYKYQVLAFATDADGRQETVQQKLSSGKKLVVDWVLNIGEQALDICIVSFNQAVSSVFVLGERSLFCLKDNGQIRFMKKLDYSPSCFIPYCSVKEGTINTLVGNHSKMLYVYQDITLKWATQLPHVPVSVKVANLQGLKGVIVTLSDNGHLQCSYLGTDPSLFQAPRVESKEINYEEFNAEMKELQKIIKEATITQDILPQSEKHRDLIVTAEVSPDLDVESQAIDSEVKAEVVPSVTIKVTIQSKMTAQQPYLAVCIQAPLAVTCDRFTFNDLEPGSSETVVLSVFLKGNFPPSELEGNCVFSCNTPTGIPKVAQCKFKLPLRLVCFPAQPSKSANHKLTIDTNKPPISFLTIFPDFADPSEEDQANVLGFQFLTGSKITLLASKTSQRYRIQSDQLEDLWLITKELTLRLEEHFKKQNCKDFACTFSGSVPLQEYFELIDRHFELRLNAEKFQELLSERAIQFRAIERRLLTRFKDKTPAPLQHLDTLLEGTFREVIALADAAEENQANMFQAFTKLKSATHLVIMLISLWQKLNADQVAIMEATFLPLAEDTQELGWEETVDSAISFLLRTCLSKSSKEQALSLSSQLSMPKDTSRLKKNISLFCDRLAKGGRLSLSTEAATQQATVVPGGCATIPESDLEERAVVPGSTAVFSSHKHTAKQKSSPDRMQEKKKKSILVDSDIMWLLYACSEINQNPWFLSLTG", "length": 908, "header": "tr|A0A8V0Z9Y7-1|A0A8V0Z3B5_CHICK Computationally mapped isoform of Bardet-Biedl syndrome 9 OS=Gallus gallus OX=9031 GN=BBS9 PE=1 SV=1 CANONICAL=A0A8V0Z3B5-1" }, "locus": { "chromosome": "2", "start_pos": 47887564, "end_pos": 47638328, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046574.1", "url": "https://www.ensembl.org/id/ENSGALT00010046574.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027732.1", "url": "https://www.ensembl.org/id/ENSGALP00010027732.1" } ] } }, { "isoform_ac": "A0A8V0ZAQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5/entry#A0A8V0ZAQ3-1", "sequence": { "sequence": "MSLFKARDWWSTVLGEKEEFDQGCLCVADVDNSGQDKIIVGSYMGYLRIFNPRPVKPGDGVQAEDLLLEVQLREPVLQVEVGKFVSGTEGLHLAVLHCRRLCVYAVSETLGNVDHGNQYQIKLMYEHHLQRTACNMTYGPFGGVKGRDLICIQSMDGMLMLFEQESYAFGRFLPGFLLPGPLTYSSRTDSFITVSSSRQVESYKYQVLAFATDADGRQETVQQKLSSGKKLVVDWVLNIGEQALDICIVSFNQAVSSVFVLGERSLFCLKDNGQIRFMKKLDYSPSCFIPYCSVKEGTINTLVGNHSKMLYVYQDITLKWATQLPHVPVSVKVANLQGLKGVIVTLSDNGHLQCSYLGTDPSLFQAPRVESKEINYEEFNAEMKELQKIIKEATITQDILPQSEKHRDLIVTAEVSPDLDVESQAIDSEVKAEVVPSVTIKVTIQSKMTAQQPYLAVCIQAPLAVTCDRFTFNDLEPGSSETVVLSVFLKGNFPPSELEGNCVFSCNTPTGIPKVAQCKFKLPLRLVCFPAQPSKSANHKLTIDTNKPPISFLTIFPDFADPSEEDQANVLGFQFLTGSKITLLASKTSQRYRIQSDQLEDLWLITKELTLRLEEHFKKQNCKDFACTFSGSVPLQEYFELIDRHFELRLNAEKFQELLSERAIQFRAIERRLLTRFKDKTPAPLQHLDTLLEGTFRERCVLEHRENLVIALADAAEENQANMFQAFTKLKSATHLVIMLISLWQKLNADQVAIMEATFLPLAEDTQELGWEETVDSAISFLLRTCLSKSSKEQALSLSSQLSMPKDTSRLKKNISLFCDRLAKGGRLSLSTEAATQQATVVPGGCATIPESDLEERAVVPGSTAVFSSHKHTAKQKSSPGLSEDAAEEAEKP", "length": 893, "header": "tr|A0A8V0ZAQ3-1|A0A8V0Z3B5_CHICK Computationally mapped isoform of Bardet-Biedl syndrome 9 OS=Gallus gallus OX=9031 GN=BBS9 PE=1 SV=1 CANONICAL=A0A8V0Z3B5-1" }, "locus": { "chromosome": "2", "start_pos": 47887564, "end_pos": 47601427, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046578.1", "url": "https://www.ensembl.org/id/ENSGALT00010046578.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027736.1", "url": "https://www.ensembl.org/id/ENSGALP00010027736.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420745", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420745", "resource": "KEGG Pathway" }, { "id": "R-GGA-5620922", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5620922", "resource": "Reactome", "description": "BBSome-mediated cargo-targeting to cilium" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "BBSome", "id": "GO:0034464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034464", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "pmid": "" }, { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "pmid": "" }, { "name": "ciliary transition zone", "id": "GO:0035869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035869", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "pmid": "" }, { "name": "pericentriolar material", "id": "GO:0000242", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "pmid": "" }, { "name": "ciliary tip", "id": "GO:0097542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097542", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "pmid": "" }, { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "pmid": "" }, { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": 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28224.0, "monoisotopic_mass": 28224.0 }, "refseq": { "ac": "NP_001384251", "name": "tRNA-splicing ligase complex subunit RTRAF isoform 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384251" }, "gene_names": [ { "name": "RTRAF", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7" } ] }, { "name": "C14orf166", "type": "synonym", "evidence": [ { "id": "NP_001384251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384251" } ] }, { "name": "C5H14orf166", "type": "synonym", "evidence": [ { "id": "NP_001384251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384251" } ] }, { "name": "CLE7", "type": "synonym", "evidence": [ { "id": "NP_001384251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384251" } ] }, { "name": "RTRAF", "type": "synonym", "evidence": [ { "id": "NP_001384251", "database": "RefSeq", 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The reference sequence was derived from AJ443517.1, CR407431.1 and CK614414.1. Transcript Variant: This variant (2) has the short first intron.", "evidence": [ { "database": "RefSeq", "id": "NP_001384251", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384251" } ] }, { "annotation": "Accessory subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Could also play a role in RNA transport.", "evidence": [ { "database": "UniProtKB", "id": "A0A1D5P7R1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R1#function" }, { "database": "UniProtKB", "id": "ARBA00094442", "url": "https://www.uniprot.org/uniprotkb/ARBA00094442#function" }, { "database": "UniProtKB", "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7#function" }, { "database": "UniProtKB", "id": "A0A8V0Z4E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RTRAF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7", "locus": { "chromosome": "5", "start_pos": 57862000, "end_pos": 57848656, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019655", "url": "https://www.ensembl.org/id/ENSGALG00010019655" } ] } } ], "crossref": [ { "id": "A0A8V0Z4D7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4D7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000012379", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000012379", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "396326", "url": "https://www.ncbi.nlm.nih.gov/gene/396326", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "A0A1D5P7R1", "url": "https://www.ebi.ac.uk/intact/interactors/id:A0A1D5P7R1*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR019265", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019265", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YPMRILR", "url": "https://omabrowser.org/oma/group/YPMRILR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5P7R1", "url": "https://www.orthodb.org/?gene=A0A1D5P7R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4D7", "url": "https://www.orthodb.org/?gene=A0A8V0Z4D7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4E7", "url": "https://www.orthodb.org/?gene=A0A8V0Z4E7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15924", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15924", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001384251", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384251", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5P7R1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5P7R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P7R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4E7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKAPSVEFWSEVTLGCVIFLDSDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSDDWPKSFEKYMKDVNCPFKMQERQETVDWLLGLAVRLEYGDNADKYKDSTPDGAKNTDNTAKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAIAKANQSKEGLPVALEKHILGFDTGDAVINEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR", "length": 247, "header": "tr|A0A8V0Z4D7-1|A0A8V0Z4D7_CHICK Isoform 1 of tRNA-splicing ligase complex subunit RTRAF OS=Gallus gallus OX=9031 GN=RTRAF PE=1 SV=1 CANONICAL=A0A8V0Z4D7-1" }, "isoforms": [ { "isoform_ac": "A0A1D5P7R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7/entry#A0A1D5P7R1-1", "sequence": { "sequence": "MFRRKLSALDYHNPGGFNCRDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSDDWPKSFEKYMKDVNCPFKMQERQETVDWLLGLAVRLEYGDNADKYKDSTPDGAKNTDNTAKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAIAKANQSKEGLPVALEKHILGFDTGDAVINEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR", "length": 244, "header": "tr|A0A1D5P7R1-1|A0A8V0Z4D7_CHICK Computationally mapped isoform of tRNA-splicing ligase complex subunit RTRAF OS=Gallus gallus OX=9031 GN=RTRAF PE=1 SV=1 CANONICAL=A0A8V0Z4D7-1" }, "locus": { "chromosome": "5", "start_pos": 57861176, "end_pos": 57848731, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047447.1", "url": "https://www.ensembl.org/id/ENSGALT00010047447.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028107.1", "url": "https://www.ensembl.org/id/ENSGALP00010028107.1" } ] } }, { "isoform_ac": "A0A8V0Z4D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7/entry#A0A8V0Z4D7-1", "sequence": { "sequence": "MKKAPSVEFWSEVTLGCVIFLDSDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSDDWPKSFEKYMKDVNCPFKMQERQETVDWLLGLAVRLEYGDNADKYKDSTPDGAKNTDNTAKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAIAKANQSKEGLPVALEKHILGFDTGDAVINEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR", "length": 247, "header": "tr|A0A8V0Z4D7-1|A0A8V0Z4D7_CHICK Isoform 1 of tRNA-splicing ligase complex subunit RTRAF OS=Gallus gallus OX=9031 GN=RTRAF PE=1 SV=1 CANONICAL=A0A8V0Z4D7-1" }, "locus": { "chromosome": "5", "start_pos": 57861176, "end_pos": 57850763, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047425.1", "url": "https://www.ensembl.org/id/ENSGALT00010047425.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028098.1", "url": "https://www.ensembl.org/id/ENSGALP00010028098.1" } ] } }, { "isoform_ac": "A0A8V0Z4E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7/entry#A0A8V0Z4E7-1", "sequence": { "sequence": "MFRRKLSALDYHNPGGFNCRDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSDDWPKSFEKYMKDVNCPFKMQERQETVDWLLGLAVRLEYGDNADKYKDSTPDGAKNTDNTAKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKVSFTGLPVALEKHILGFDTGDAVINEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR", "length": 225, "header": "tr|A0A8V0Z4E7-1|A0A8V0Z4E7_CHICK Computationally mapped isoform of tRNA-splicing ligase complex subunit RTRAF OS=Gallus gallus OX=9031 GN=RTRAF PE=1 SV=1 CANONICAL=A0A8V0Z4D7-1" }, "locus": { "chromosome": "5", "start_pos": 57861176, "end_pos": 57848731, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047454.1", "url": "https://www.ensembl.org/id/ENSGALT00010047454.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028108.1", "url": "https://www.ensembl.org/id/ENSGALP00010028108.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287B7A0-1", "protein_name": "tRNA-splicing ligase complex subunit RTRAF", "gene_name": "RTRAF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFRRKLTALDYHNPAGFNCKDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSSDWPKFFEKYLRDVNCPFKIQDRQEAIDWLLGLAVRLEYGDNANHISTTAKDGILGTKFTEKYKDLVPDNTKNADNAAKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAVAKANQTKEGLPVALDKHILGFDTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR", "length": 261 }, "evidence": [ { "id": "A0A8V0Z4D7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4D7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q553E8-1", "protein_name": "RNA transcription, translation and transport factor protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSLIKKLSILNYPNKDSLNLNEREQFISVISYLLEKLYNSSDISELLNVTDEWENQFKNFISQKQIPINVDNLTDIKEKEKVVTIFTNFLIKNQYKENVEQIHETKYKCLQRYKLENVNFDENNLTEAVHSLAKLFNYDIKPTDVHYTALLSMIVRVAERKFNDVPSLIKDEEERKKKLETTTTTTTTSTTTNNNNDNLNDNSKNEIVNNNIFPLGFDFKDDKMNSAATILRLLYVSDLRELQNKINQVLSIVQNYTANPETNFKLAVVGR", "length": 271 }, "evidence": [ { "id": "A0A8V0Z4D7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4D7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7ZUH1-1", "protein_name": "tRNA-splicing ligase complex subunit RTRAF", "gene_name": "rtraf", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFRRKLTALEYHNPTGFDCKDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIPSSDWPKYFEKYLQDVNCPFSVQERQETVDWLLGLAVRFEYGDNVEKYRNCKPVTETNDVQKSADPLINLDSNNPDFKAGVLALANLLKIQRHDDYLVMLKAIKILVQERLTPDAIAKASQAKEGLPVTLDKHILGFDTGDATLNEAAQVLRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR", "length": 242 }, "evidence": [ { "id": "A0A8V0Z4D7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4D7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CQE8-1", "protein_name": "tRNA-splicing ligase complex subunit RTRAF", "gene_name": "RTRAF", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFRRKLTALDYHNPSGFNCKDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSSDWPKFFEKYLKDVNCPFKIQDRQEAIDWLLGLAVRLEYGDNAEKYKDLVPDNRKNTDNAAKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAVAKANQTKEGLPVALEKHILGFDTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR", "length": 244 }, "evidence": [ { "id": "A0A8V0Z4D7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4D7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VEG8-1", "protein_name": "RNA transcription, translation and transport factor protein", "gene_name": "CG7477", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSLKMKLEVLGRPDVDIPVVMSDRKEFANTVLWLEDQKIRLYSIEDRCKLRTVDNPEIWKEGYLKYCADLSMPPLETRQEQLAWIVSYAVRLDFLDDPDQFASINTKQVPPQSNGKQSQQRVQAIFDGNINTQEKAFVDGVRLLASKLNVPHHPNHLLQLEAIARVVHERLSPAAKDRKPVVGKPFPFDKGNDVVSSNDSALDLPMRILRLLQIQSLRELQTHINETIVAVQNITANPKTDTKLGKVGF", "length": 250 }, "evidence": [ { "id": "A0A8V0Z4D7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4D7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y224-1", "protein_name": "tRNA-splicing ligase complex subunit RTRAF", "gene_name": "RTRAF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFRRKLTALDYHNPAGFNCKDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSSDWPKFFEKYLRDVNCPFKIQDRQEAIDWLLGLAVRLEYGDNAEKYKDLVPDNSKTADNATKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAVAKANQTKEGLPVALDKHILGFDTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR", "length": 244 }, "evidence": [ { "id": "A0A8V0Z4D7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4D7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7" } ], "pmid": "" }, { "name": "RNA polymerase II complex binding", "id": "GO:0000993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000993", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7" } ], "pmid": "" }, { "name": "tRNA-splicing ligase complex", "id": "GO:0072669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072669", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7" } ], "pmid": "" }, { "name": "tRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0006388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006388", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 176, "end_pos": 178 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z446-1", "uniprot_ac": "A0A8V0Z446", "uniprot_id": "A0A8V0Z446_CHICK", "mass": { "chemical_mass": 17913.0, "monoisotopic_mass": 17913.0 }, "refseq": { "ac": "XP_421706", "name": "golgin subfamily A member 7B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421706" }, "gene_names": [ { "name": "GOLGA7B", "type": "recommended", "evidence": [ { "id": "A0A8V0Z446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446" } ] }, { "name": "GOLGA7B", "type": "synonym", "evidence": [ { "id": "XP_421706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421706" } ] } ], "protein_names": [ { "name": "Golgin A7 family member B", "type": "synonym", "evidence": [ { "id": "A0A8V0Z446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446/entry#names_and_taxonomy" } ] }, { "name": "golgin subfamily A member 7B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_421706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421706" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jan 4, 2016 this sequence version replaced XP_421706.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421706" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z446", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GOLGA7B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446", "locus": { "chromosome": "6", "start_pos": 23077781, "end_pos": 23083216, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017891", "url": "https://www.ensembl.org/id/ENSGALG00010017891" } ] } } ], "crossref": [ { "id": "A0A8V0Z446", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z446", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000031372", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000031372", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "423837", "url": "https://www.ncbi.nlm.nih.gov/gene/423837", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423837", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423837", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A1D5PEN0", "url": "https://www.orthodb.org/?gene=A0A1D5PEN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0YX94", "url": "https://www.orthodb.org/?gene=A0A8V0YX94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z446", "url": "https://www.orthodb.org/?gene=A0A8V0Z446", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB35", "url": "https://www.orthodb.org/?gene=A0A8V0ZB35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13254", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13254", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13254:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13254:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_421706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421706", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PEN0", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PEN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PEN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX94", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0YX94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YX94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z446", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z446-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB35", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATEVHSLQELRRSASLATKVFVQRDYSDGTTCQFQTKFPPELESRIERQLFEETVKTLNGFYAEAEKIGGSSYLEGCLACATAYFIFLCMETHYEKVLKKISKYIQEQNEKVYAPRGLLLTDPLERGMRVIEISIYEDRCSSGSSSSGSSSSSSSGGGGR", "length": 161, "header": "tr|A0A8V0Z446-1|A0A8V0Z446_CHICK Isoform 1 of Golgin A7 family member B OS=Gallus gallus OX=9031 GN=GOLGA7B PE=3 SV=1 CANONICAL=A0A8V0Z446-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PEN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446/entry#A0A1D5PEN0-1", "sequence": { "sequence": "MRPSPARCPGAVSLPWGVPSALLLHLFLCPHPAPTQWAGGQTLVPVTLCGPATSPATACVTLHGTETRTGTMGAAPSAVETSGMASPGDTVHSLQELRRSASLATKVFVQRDYSDGTTCQFQTKFPPELESRIERQLFEETVKTLNGFYAEAEKIGGSSYLEGCLACATAYFIFLCMETHYEKVLKKISKYIQEQNEKVYAPRGLLLTDPLERGMRVIEISIYEDRCSSGSSSSGSSSSSSSGGGGR", "length": 247, "header": "tr|A0A1D5PEN0-1|A0A8V0Z446_CHICK Computationally mapped isoform of Golgin A7 family member B OS=Gallus gallus OX=9031 GN=GOLGA7B PE=3 SV=2 CANONICAL=A0A8V0Z446-1" }, "locus": { "chromosome": "6", "start_pos": 23083017, "end_pos": 23078638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043254.1", "url": "https://www.ensembl.org/id/ENSGALT00010043254.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025702.1", "url": "https://www.ensembl.org/id/ENSGALP00010025702.1" } ] } }, { "isoform_ac": "A0A8V0YX94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446/entry#A0A8V0YX94-1", "sequence": { "sequence": "MRPSPARCPGAVSLPWGVPSALLLHLFLCPHPAPTQWAGGQTLVPVTLCGPATSPATACVTLHGTETRTGTMGAAPSAVETSGMASPGDTIERQLFEETVKTLNGFYAEAEKIGGSSYLEGCLACATAYFIFLCMETHYEKVLKKISKYIQEQNEKVYAPRGLLLTDPLERGMRVIEISIYEDRCSSGSSSSGSSSSSSSGGGGR", "length": 205, "header": "tr|A0A8V0YX94-1|A0A8V0Z446_CHICK Computationally mapped isoform of Golgin A7 family member B OS=Gallus gallus OX=9031 GN=GOLGA7B PE=3 SV=1 CANONICAL=A0A8V0Z446-1" }, "locus": { "chromosome": "6", "start_pos": 23083017, "end_pos": 23078638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043255.1", "url": "https://www.ensembl.org/id/ENSGALT00010043255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025703.1", "url": "https://www.ensembl.org/id/ENSGALP00010025703.1" } ] } }, { "isoform_ac": "A0A8V0Z446-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446/entry#A0A8V0Z446-1", "sequence": { "sequence": "MATEVHSLQELRRSASLATKVFVQRDYSDGTTCQFQTKFPPELESRIERQLFEETVKTLNGFYAEAEKIGGSSYLEGCLACATAYFIFLCMETHYEKVLKKISKYIQEQNEKVYAPRGLLLTDPLERGMRVIEISIYEDRCSSGSSSSGSSSSSSSGGGGR", "length": 161, "header": "tr|A0A8V0Z446-1|A0A8V0Z446_CHICK Isoform 1 of Golgin A7 family member B OS=Gallus gallus OX=9031 GN=GOLGA7B PE=3 SV=1 CANONICAL=A0A8V0Z446-1" }, "locus": { "chromosome": "6", "start_pos": 23080171, "end_pos": 23078638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043247.1", "url": "https://www.ensembl.org/id/ENSGALT00010043247.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025697.1", "url": "https://www.ensembl.org/id/ENSGALP00010025697.1" } ] } }, { "isoform_ac": "A0A8V0ZB35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446/entry#A0A8V0ZB35-1", "sequence": { "sequence": "MRPSPARCPGAVSLPWGVPSALLLHLFLCPHPAPTQWAGGQTLVPVTLCGPATSPATACVTLHGTETRTGTMGAAPSAVETSGMASPGDTVLKKISKYIQEQNEKVYAPRGLLLTDPLERGMRVIEISIYEDRCSSGSSSSGSSSSSSSGGGGR", "length": 154, "header": "tr|A0A8V0ZB35-1|A0A8V0Z446_CHICK Computationally mapped isoform of Golgin A7 family member B OS=Gallus gallus OX=9031 GN=GOLGA7B PE=3 SV=1 CANONICAL=A0A8V0Z446-1" }, "locus": { "chromosome": "6", "start_pos": 23083017, "end_pos": 23078638, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043250.1", "url": "https://www.ensembl.org/id/ENSGALT00010043250.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025699.1", "url": "https://www.ensembl.org/id/ENSGALP00010025699.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423837", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423837", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z446", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446" } ], "pmid": "" }, { "name": "palmitoyltransferase complex", "id": "GO:0002178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002178", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z446", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z446", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z446" }, { "id": "PF10256", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10256" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Golgin subfamily A member 7/ERF4", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 133, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z2Z9-1", "uniprot_ac": "A0A8V0Z2Z9", "uniprot_id": "A0A8V0Z2Z9_CHICK", "mass": { "chemical_mass": 64573.0, "monoisotopic_mass": 64573.0 }, "refseq": {}, "gene_names": [ { "name": "ZNF362", "type": "recommended", "evidence": [ { "id": "A0A8V0Z2Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9" } ] } ], "protein_names": [ { "name": "Zinc finger protein 362", "type": "synonym", "evidence": [ { "id": "A0A8V0Z2Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF362", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9", "locus": { "chromosome": "21", "start_pos": 6490843, "end_pos": 6509723, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017704", "url": "https://www.ensembl.org/id/ENSGALG00010017704" } ] } } ], "crossref": [ { "id": "A0A8V0Z2Z9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z2Z9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000026558", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000026558", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100859829", "url": "https://www.ncbi.nlm.nih.gov/gene/100859829", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CWMAEPR", "url": "https://omabrowser.org/oma/group/CWMAEPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A1D5PV22", "url": "https://www.orthodb.org/?gene=A0A1D5PV22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2Z9", "url": "https://www.orthodb.org/?gene=A0A8V0Z2Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z304", "url": "https://www.orthodb.org/?gene=A0A8V0Z304", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZA01", "url": "https://www.orthodb.org/?gene=A0A8V0ZA01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A1D5PV22", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PV22-1", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z304", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z304", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z304-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z304-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA01", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA01-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWERRRRGTERGRPPTPPIPPSPFGLFVCGGSPPPGQEQLHSAPNFVLLSRSAFVFLLTPPPPPIFFFLYFLSPPLLLAPPPRGGGTPLRVPPPSFPTQEEEEGGGRGGGSQEDARFAGFSLFLPPEGLMEKLIAAERPHPCGGARRGAADAAWGLGCLSLEKRPACSTGSQLDLEMDADKGKQRQYSQRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSVASQQPLLVPPSPAESSQSIMSLPKLQQVPGLHPQAVPQPDVALHARPATSTVTGLGLASRAPTVSTSESSTGTTTPSTPTSTSQSRLIASSPTLISGITSPPLLDSIKTIQGHSLLGAPKAERGRKKIKAENPSGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCEKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYTDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSQHSPQRTESPGIPVRISLI", "length": 591, "header": "tr|A0A8V0Z2Z9-1|A0A8V0Z2Z9_CHICK Isoform 1 of Zinc finger protein 362 OS=Gallus gallus OX=9031 GN=ZNF362 PE=3 SV=1 CANONICAL=A0A8V0Z2Z9-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PV22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9/entry#A0A1D5PV22-1", "sequence": { "sequence": "MAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSVASQQPLLVPPSPAESSQSIMSLPKLQQVPGLHPQAVPQPDVALHARPATSTVTGLGLASRAPTVSTSESSTGTTTPSTPTSTSQSRLIASSPTLISGITSPPLLDSIKTIQGHSLLGAPKAERGRKKIKAENPSGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCEKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYTDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSQHSPQRTESPGIPVRISLI", "length": 401, "header": "tr|A0A1D5PV22-1|A0A8V0Z2Z9_CHICK Computationally mapped isoform of Zinc finger protein 362 OS=Gallus gallus OX=9031 GN=ZNF362 PE=3 SV=2 CANONICAL=A0A8V0Z2Z9-1" }, "locus": { "chromosome": "21", "start_pos": 6493133, "end_pos": 6491086, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042802.1", "url": "https://www.ensembl.org/id/ENSGALT00010042802.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025292.1", "url": "https://www.ensembl.org/id/ENSGALP00010025292.1" } ] } }, { "isoform_ac": "A0A8V0Z2Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9/entry#A0A8V0Z2Z9-1", "sequence": { "sequence": "MWERRRRGTERGRPPTPPIPPSPFGLFVCGGSPPPGQEQLHSAPNFVLLSRSAFVFLLTPPPPPIFFFLYFLSPPLLLAPPPRGGGTPLRVPPPSFPTQEEEEGGGRGGGSQEDARFAGFSLFLPPEGLMEKLIAAERPHPCGGARRGAADAAWGLGCLSLEKRPACSTGSQLDLEMDADKGKQRQYSQRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSVASQQPLLVPPSPAESSQSIMSLPKLQQVPGLHPQAVPQPDVALHARPATSTVTGLGLASRAPTVSTSESSTGTTTPSTPTSTSQSRLIASSPTLISGITSPPLLDSIKTIQGHSLLGAPKAERGRKKIKAENPSGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCEKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYTDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSQHSPQRTESPGIPVRISLI", "length": 591, "header": "tr|A0A8V0Z2Z9-1|A0A8V0Z2Z9_CHICK Isoform 1 of Zinc finger protein 362 OS=Gallus gallus OX=9031 GN=ZNF362 PE=3 SV=1 CANONICAL=A0A8V0Z2Z9-1" }, "locus": { "chromosome": "21", "start_pos": 6500230, "end_pos": 6491086, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042800.1", "url": "https://www.ensembl.org/id/ENSGALT00010042800.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025290.1", "url": "https://www.ensembl.org/id/ENSGALP00010025290.1" } ] } }, { "isoform_ac": "A0A8V0Z304-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9/entry#A0A8V0Z304-1", "sequence": { "sequence": "MAEKALRSHGSEKRPACSTGSQLDLEMDADKGKQRQYSQRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSVASQQPLLVPPSPAESSQSIMSLPKLQQVPGLHPQAVPQPDVALHARPATSTVTGLGLASRAPTVSTSESSTGTTTPSTPTSTSQSRLIASSPTLISGITSPPLLDSIKTIQGHSLLGAPKAERGRKKIKAENPSGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCEKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYTDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSQHSPQRTESPGIPVRISLI", "length": 441, "header": "tr|A0A8V0Z304-1|A0A8V0Z304_CHICK Computationally mapped isoform of Zinc finger protein 362 OS=Gallus gallus OX=9031 GN=ZNF362 PE=3 SV=1 CANONICAL=A0A8V0Z2Z9-1" }, "locus": { "chromosome": "21", "start_pos": 6500682, "end_pos": 6491086, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042805.1", "url": "https://www.ensembl.org/id/ENSGALT00010042805.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025295.1", "url": "https://www.ensembl.org/id/ENSGALP00010025295.1" } ] } }, { "isoform_ac": "A0A8V0ZA01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9/entry#A0A8V0ZA01-1", "sequence": { "sequence": "MDTHLQLLEGIIHVGDLVLFVHSRLITEEADNEKRPACSTGSQLDLEMDADKGKQRQYSQRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSVASQQPLLVPPSPAESSQSIMSLPKLQQVPGLHPQAVPQPDVALHARPATSTVTGLGLASRAPTVSTSESSTGTTTPSTPTSTSQSRLIASSPTLISGITSPPLLDSIKTIQGHSLLGAPKAERGRKKIKAENPSGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCEKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYTDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSQHSPQRTESPGIPVRISLI", "length": 462, "header": "tr|A0A8V0ZA01-1|A0A8V0Z2Z9_CHICK Computationally mapped isoform of Zinc finger protein 362 OS=Gallus gallus OX=9031 GN=ZNF362 PE=3 SV=1 CANONICAL=A0A8V0Z2Z9-1" }, "locus": { "chromosome": "21", "start_pos": 6509524, "end_pos": 6491086, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042807.1", "url": "https://www.ensembl.org/id/ENSGALT00010042807.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025297.1", "url": "https://www.ensembl.org/id/ENSGALP00010025297.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 207, "start_aa": "Thr", "end_pos": 207, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr207", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2QLC4-1", "protein_name": "Zinc finger protein 362", "gene_name": "Znf362", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRSSPSGKGPSRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQAVMSLPKLQQVPGLHPQSVPQPDVALHARPATSTVTGLGLSSRTPAVSTSESTPGTGTGTSTPSTPTTTSQSRLIASSPTLISGITSPPLLDSIKTIQGHGLLGPPKSERGRKKIKAENPGGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCDKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYSDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSHHSPQRTESPGIPVRISLI", "length": 418 }, "evidence": [ { "id": "A0A8V0Z2Z9", "url": "https://omabrowser.org/oma/group/A0A8V0Z2Z9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I5ZWA1-1", "protein_name": "Zinc finger protein 362", "gene_name": "Zfp362", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSSPSGKGPSRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQAVMSLPKLQQVPGLHPQSVPQPDVALHARPATSTVTGLGLSSRTPAVSTSESTPGTGTGTSTPSTPTTTSQSRLIASSPTLISGITSPPLLDSIKTIQGHGLLGPPKSERGRKKIKAENPGGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCDKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYSDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSHHSPQRTESPGIPVRISLI", "length": 418 }, "evidence": [ { "id": "A0A8V0Z2Z9", "url": "https://omabrowser.org/oma/group/A0A8V0Z2Z9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9TKU4-1", "protein_name": "Zinc finger protein 362", "gene_name": "ZNF362", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDEKTDRKWNDRCLMMEMQGTEGTEKRGAQHSLAVPEGFQEEVAFKLGPKEMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQAVMSLPKLQQVPGLHPQAVPQPDVALHARPATSTVTGLGISSRTPAVSTSESSAGTGTSSPSTPTTTSQSRLIASSPTLISGITSPPLLDSIKTIQGHGLLGPPKSERGRKKIKAENPGGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCDKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYSDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSHHSPQRTESPSIPVRISLI", "length": 454 }, "evidence": [ { "id": "A0A8V0Z2Z9", "url": "https://omabrowser.org/oma/group/A0A8V0Z2Z9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B1ASA5-1", "protein_name": "Zinc finger protein 362", "gene_name": "Zfp362", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRSSPSGKGPSRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQAVMSLPKLQQVPGLHPQSVPQPDVALHARPATSTVTGLGLSSRTPAVSTSESTPGTGTGTSTPSTPTTTSQSRLIASSPTLISGITSPPLLDSIKTIQGHGLLGPPKSERGRKKIKAENPGGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCDKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYSDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSHHSPQRTESPGIPVRISLI", "length": 418 }, "evidence": [ { "id": "A0A8V0Z2Z9", "url": "https://omabrowser.org/oma/group/A0A8V0Z2Z9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5T0B9-1", "protein_name": "Zinc finger protein 362", "gene_name": "ZNF362", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSSPSGKGHSRMAEPRFNNPYFWPPPPTMPSQLDNLVLINKIKEQLMAEKIRPPHLPPTSASSQQPLLVPPAPAESSQAVMSLPKLQQVPGLHPQAVPQPDVALHARPATSTVTGLGLSTRTPSVSTSESSAGAGTGTGTSTPSTPTTTSQSRLIASSPTLISGITSPPLLDSIKTIQGHGLLGPPKSERGRKKIKAENPGGPPVLVVPYPILASGETAKEGKTYRCKVCPLTFFTKSEMQIHSKSHTEAKPHKCPHCSKSFANASYLAQHLRIHLGVKPYHCSYCDKSFRQLSHLQQHTRIHTGDRPYKCPHPGCEKAFTQLSNLQSHQRQHNKDKPYKCPNCYRAYSDSASLQIHLSAHAIKHAKAYCCSMCGRAYTSETYLMKHMSKHTVVEHLVSHHSPQRTESPGIPVRISLI", "length": 420 }, "evidence": [ { "id": "A0A8V0Z2Z9", "url": "https://omabrowser.org/oma/group/A0A8V0Z2Z9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z2Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2Z9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 398, "end_pos": 425, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 16, 207 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 437, "end_pos": 439 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z417-1", "uniprot_ac": "A0A8V0Z417", "uniprot_id": "A0A8V0Z417_CHICK", "mass": { "chemical_mass": 63705.0, "monoisotopic_mass": 63705.0 }, "refseq": {}, "gene_names": [ { "name": "APLF", "type": "recommended", "evidence": [ { "id": "A0A8V0Z417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ] } ], "protein_names": [ { "name": "Aprataxin and PNKP like factor", "type": "synonym", "evidence": [ { "id": "A0A8V0Z417", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "APLF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417", "locus": { "chromosome": "3", "start_pos": 11565620, "end_pos": 11542297, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017867", "url": "https://www.ensembl.org/id/ENSGALG00010017867" } ] } } ], "crossref": [ { "id": "A0A8V0Z417", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z417", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008745", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008745", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421264", "url": "https://www.ncbi.nlm.nih.gov/gene/421264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PCFYRSS", "url": "https://omabrowser.org/oma/group/PCFYRSS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TSM9", "url": "https://www.orthodb.org/?gene=A0A3Q2TSM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3I6", "url": "https://www.orthodb.org/?gene=A0A8V0Z3I6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z417", "url": "https://www.orthodb.org/?gene=A0A8V0Z417", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E1BU46", "url": "https://www.orthodb.org/?gene=E1BU46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21315", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21315", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21315:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21315:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10283", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10283", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2TSM9", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TSM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TSM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3I6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3I6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z417-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BU46", "url": "https://www.uniprot.org/uniprotkb/E1BU46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BU46-1", "url": "https://www.uniprot.org/uniprotkb/E1BU46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSRRTAVPSVAPHCCLLQTRRKAPVLRFFQFFQRSVTLRGYSNGMPFAFRTLSAYGRRQPALSGAQITDKRVSRKHAILEVVGGQVRIKPIHVDSCFYQSPENGRLLPLEAHEWHSLKFGDSFSLMVDKYIFKVLSAQPVESTERNNQKADAEAAVSVHPAEISCSPSLPEPACSTSEMQDSSEIRQNESISTHLVPFCDDDESEQSKSIQRRRVLPSWMLEKDLLVPKISEPIMKGGNRNKKSQGRGKRHMESLKSEVSILQRKRSASEEIEEDFEDEEQDEEEGRCLSTSSLQNASGFPLESTVGNMERNGKTETKKPGSSMEKSDRQLQSKRSKPSGHISSKTNRLEESENKGQLTCSTSQQAPLGRTSPIGAQESAHEPSADVDYDAEISYTTKVAEASEGSKQRKHKRTPCMYGAGCYRKNPVHFQQFSHPNDDDYYETGSVTQDDNDNRPECPYGTACYRKNPQHKLEYKHTVPPVTERRTRQRTSKNGKRGLEEDSDNDGEPNEYDLNDSFIDDEEEECEPTDEDSDWEPSSEEKDNEDVETLVKEAQRFVKTKK", "length": 563, "header": "tr|A0A8V0Z417-1|A0A8V0Z417_CHICK Isoform 1 of Aprataxin and PNKP like factor OS=Gallus gallus OX=9031 GN=APLF PE=1 SV=1 CANONICAL=A0A8V0Z417-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TSM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417/entry#A0A3Q2TSM9-1", "sequence": { "sequence": "MAGVRLAPCDGGCPVALPPGETLLGRGPLLGITDKRVSRKHAILEVVGGQVRIKPIHVDSCFYQSPENGRLLPLEAHEWHSLKFGDSFSLMVDKYIFKVLSAQPVESTERNNQKADAEAAVSVHPAEISCSPSLPEPACSTSEMQDSSEIRQNESISTHLVPFCDDDESEQSKSIQRRRVLPSWMLEKDLLVPKISEPIMKGGNRNKKSQGRGKRHMESLKSEVSILQRKRSASEEIEEDFEDEEQDEEEGRCLSTSSLQNASGFPLESTVGNMERNGKTETKKPGSSMEKSDRQLQSKRSKPSGHISSKTNRLEESENKGQLTCSTSQQAPLGRTSPIGAQESAHEPSADVDYDAEISYTTKVAEASEGSKQRKHKRTPCMYGAGCYRKNPVHFQQFSHPNDDDYYETGSVTQDDNDNRPECPYGTACYRKNPQHKLEYKHTVPPVTERRTRQRTSKNGKRGLEEDSDNDGEPNEYDLNDSFIDDEEEECEPTDEDSDWEPSSEEKDNEDVETLVKEAQRFVKTKKWRIL", "length": 531, "header": "tr|A0A3Q2TSM9-1|A0A8V0Z417_CHICK Computationally mapped isoform of Aprataxin and PNKP like factor OS=Gallus gallus OX=9031 GN=APLF PE=1 SV=1 CANONICAL=A0A8V0Z417-1" }, "locus": { "chromosome": "3", "start_pos": 11565522, "end_pos": 11543096, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043201.1", "url": "https://www.ensembl.org/id/ENSGALT00010043201.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025665.1", "url": "https://www.ensembl.org/id/ENSGALP00010025665.1" } ] } }, { "isoform_ac": "A0A8V0Z3I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417/entry#A0A8V0Z3I6-1", "sequence": { "sequence": "MWRSVGWERAQWCGSDGGDAITDKRVSRKHAILEVVGGQVRIKPIHVDSCFYQSPENGRLLPLEAHEWHSLKFGDSFSLMVDKYIFKVLSAQPVESTERNNQKADAEAAVSVHPAEISCSPSLPEPACSTSEMQDSSEIRQNESISTHLVPFCDDDESEQSKSIQRRRVLPSWMLEKDLLVPKISEPIMKGGNRNKKSQGRGKRHMESLKSEVSILQRKRSASEEIEEDFEDEEQDEEEGRCLSTSSLQNASGFPLESTVGNMERNGKTETKKPGSSMEKSDRQLQSKRSKPSGHISSKTNRLEESENKGQLTCSTSQQAPLGRTSPIGAQESAHEPSADVDYDAEISYTTKVAEASEGSKQRKHKRTPCMYGAGCYRKNPVHFQQFSHPNDDDYYETGSVTQDDNDNRPECPYGTACYRKNPQHKLEYKHTVPPVTERRTRQRTSKNGKRGLEEDSDNDGEPNEYDLNDSFIDDEEEECEPTDEDSDWEPSSEEKDNEDVETLVKEAQRFVKTKK", "length": 516, "header": "tr|A0A8V0Z3I6-1|A0A8V0Z3I6_CHICK Computationally mapped isoform of Aprataxin and PNKP like factor OS=Gallus gallus OX=9031 GN=APLF PE=1 SV=1 CANONICAL=A0A8V0Z417-1" }, "locus": { "chromosome": "3", "start_pos": 11563668, "end_pos": 11543269, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043194.1", "url": "https://www.ensembl.org/id/ENSGALT00010043194.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025660.1", "url": "https://www.ensembl.org/id/ENSGALP00010025660.1" } ] } }, { "isoform_ac": "A0A8V0Z417-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417/entry#A0A8V0Z417-1", "sequence": { "sequence": "MLSRRTAVPSVAPHCCLLQTRRKAPVLRFFQFFQRSVTLRGYSNGMPFAFRTLSAYGRRQPALSGAQITDKRVSRKHAILEVVGGQVRIKPIHVDSCFYQSPENGRLLPLEAHEWHSLKFGDSFSLMVDKYIFKVLSAQPVESTERNNQKADAEAAVSVHPAEISCSPSLPEPACSTSEMQDSSEIRQNESISTHLVPFCDDDESEQSKSIQRRRVLPSWMLEKDLLVPKISEPIMKGGNRNKKSQGRGKRHMESLKSEVSILQRKRSASEEIEEDFEDEEQDEEEGRCLSTSSLQNASGFPLESTVGNMERNGKTETKKPGSSMEKSDRQLQSKRSKPSGHISSKTNRLEESENKGQLTCSTSQQAPLGRTSPIGAQESAHEPSADVDYDAEISYTTKVAEASEGSKQRKHKRTPCMYGAGCYRKNPVHFQQFSHPNDDDYYETGSVTQDDNDNRPECPYGTACYRKNPQHKLEYKHTVPPVTERRTRQRTSKNGKRGLEEDSDNDGEPNEYDLNDSFIDDEEEECEPTDEDSDWEPSSEEKDNEDVETLVKEAQRFVKTKK", "length": 563, "header": "tr|A0A8V0Z417-1|A0A8V0Z417_CHICK Isoform 1 of Aprataxin and PNKP like factor OS=Gallus gallus OX=9031 GN=APLF PE=1 SV=1 CANONICAL=A0A8V0Z417-1" }, "locus": { "chromosome": "3", "start_pos": 11563668, "end_pos": 11542496, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043205.1", "url": "https://www.ensembl.org/id/ENSGALT00010043205.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025667.1", "url": "https://www.ensembl.org/id/ENSGALP00010025667.1" } ] } }, { "isoform_ac": "E1BU46-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417/entry#E1BU46-1", "sequence": { "sequence": "MAGVRLAPCDGGCPVALPPGETLLGRGPLLGITDKRVSRKHAILEVVGGQVRIKPIHVDSCFYQSPENGRLLPLEAHEWHSLKFGDSFSLMVDKYIFKVLSAQPVESTERNNQKADAEAAVSVHPAEISCSPSLPEPACSTSEMQDSSEIRQNESISTHLVPFCDDDESEQSKSIQRRRVLPSWMLEKDLLVPKISEPIMKGGNRNKKSQGRGKRHMESLKSEVSILQRKRSASEEIEEDFEDEEQDEEEGRCLSTSSLQNASGFPLESTVGNMERNGKTETKKPGSSMEKSDRQLQSKRSKPSGHISSKTNRLEESENKGQLTCSTSQQAPLGRTSPIGAQESAHEPSADVDYDAEISYTTKVAEASEGSKQRKHKRTPCMYGAGCYRKNPVHFQQFSHPNDDDYYETGSVTQDDNDNRPECPYGTACYRKNPQHKLEYKHTVPPVTERRTRQRTSKNGKRGLEEDSDNDGEPNEYDLNDSFIDDEEEECEPTDEDSDWEPSSEEKDNEDVETLVKEAQRFVKTKK", "length": 527, "header": "tr|E1BU46-1|A0A8V0Z417_CHICK Computationally mapped isoform of Aprataxin and PNKP like factor OS=Gallus gallus OX=9031 GN=APLF PE=1 SV=2 CANONICAL=A0A8V0Z417-1" }, "locus": { "chromosome": "3", "start_pos": 11563668, "end_pos": 11543096, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043199.1", "url": "https://www.ensembl.org/id/ENSGALT00010043199.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025664.1", "url": "https://www.ensembl.org/id/ENSGALP00010025664.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0JNH9-1", "protein_name": "Aprataxin and PNK-like factor", "gene_name": "APLF", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGGFELQPQDGGPRVALAPGETVIGRGPLLGLHRNPCYYQSSEKSQLLPLKTNIWCWLNPGDHFSLLVDKYIFCVLSTHSEMEMECTLRNSQMLDEDDILNEIPKSSSADLPDKTPSAPRRERSTETAKPQAAANNMSFIGESRDLSKQQPNPSERKRILPAWMLTENSSDQNLSVISGGNNVTWESEKERVCKDKTQVNITQPGKKRLISSGSSESTSAKQDTGKKCKNDDQEESIISSKEMPQSFSAAMLHNTEIDNTKTNPQRSKVPVEALGKVSEHKIITKGSSNEDSTARSCSESYSSTQSKSFCDKPQKSHPEPSSNPPSPECVQAKATDSVPNGSEENKVQRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVNITCQDEADDRPECPYGASCYRKNPQHKIEYRHSTFPVRSISDEDDNVGQPNEYNLNDSFIDDEEEEYEPTDEDSDWEPEKEDLEKEDMEGLLKEAKKFMKRKK", "length": 485 }, "evidence": [ { "id": "A0A8V0Z417", "url": "https://omabrowser.org/oma/group/A0A8V0Z417/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F6Q5G6-1", "protein_name": "Aprataxin and PNK-like factor", "gene_name": "Aplf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSEFFLHPLDGGPRVPVGPGQTVIGRGPLLGITDKRVSRRHAILEVVDSQLRIKPVHKNPCFHQSSEKSQLSPMETHVWSRLHPGDSFSLLLDKYAFRVSSTQSEVEVESTLRNSQMLDEDDILNEMRKSPVVNLPDKAAGASQLQGSPEVTKTKCPPIDPMARDSSSGDCRAFSEHQPDPAHRKRILPAWMLAGSLSDQNLSTPAEGGGDKDAIQRDGKEGTHEDKTPVNTSWRGRKRFIPPGNSKSVSPKQDPGKKWRRSDQEGLAVSPEDVPESSSSITVSDPDMDIVKANKLSDTISAEELGEAPKHKAVTKPTTNDKDKTMSHPKCRAGVQSKTFLEKSQGCHPESSSAPSSPGASHTDTADSVLGCSEESKVRRTSCMYGANCYRKNPLHFQHFSHPGDSDYGAVPVTDEGVTGDRPECPYGASCYRKNPQHRMEYRHSALPARVAVDEDDDDVGQPSDSDKDEEDYAPTDEDSDWQPGKDDEEKEDVDELLKEAKRFMRRKT", "length": 510 }, "evidence": [ { "id": "A0A8V0Z417", "url": "https://omabrowser.org/oma/group/A0A8V0Z417/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HIE4-1", "protein_name": "Aprataxin and PNK-like factor", "gene_name": "Aplf", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSWDFFLQPLDGGAQVPVRPGQTVIGRGPLLGITDKRVSRRHAILEVVDNQLRIKPIHTNPCFHQSSEKSQLLPMKTHVWCWLNPGDIFSLLLNKYSFRVFSTQTEEEVECTLRNSQIFDEDDVLSEMQKSPVINLPDKTTGTSQLQGSPEITKAKCTAIEPMSSAGACGDIREHKLHPAQRKRILPAWMLAESSSGQNLSAPVKGGDKDGIQRSGKEGTCKDKTPVNVTQHGRKRLISPGNLDSKSAEQDPGKKCKSSDQEGLVVSSKEVPESLSSITLSDTDVDSVKINEPSNAVPIEELGEVSKHKTVSKATANEEGETVRHAESHSGVHSKSLLETSQGFHPKSSSAPSSPDASHTMADSVLGSSEESKVQRVSCMYGANCYRKNPLHFQHFSHPGDSDYGDIQVTDEGETGDRPECPYGASCYRKNPQHKMEYRHSALPVRDKDNDDGGHPSENDLNDSFLEDDDEEEGYEPTDEDSDWQPEKDDEEKEDVEELLKEAKRFMKRKK", "length": 511 }, "evidence": [ { "id": "A0A8V0Z417", "url": "https://omabrowser.org/oma/group/A0A8V0Z417/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9D842-1", "protein_name": "Aprataxin and PNK-like factor", "gene_name": "Aplf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSDFFLQPLDGGPRVPVGPGQTVIGRGPLLGITDKRVSRRHAILEVVDSQLRIKPIHRNPCFYQSSEKSQHSPMETQVWSQLHPGDSFSLLLDKYAFRVFSAESEVEMECTLRNSQMLDEDDILSEMQKSPVVNLPDKTTGASQLQGSPEITKTKCPTIDPMSSSGECRAFSEHQPRPTQRKRILPAWMLAESLSDQSLSTPAEGGDKDVIQRSGKAGTCEDRTPGNTSWHGKKRLSPSGNSKSVSAEQDPGKKCRKADQEGPGVSSENVPESSSSNIVKDPDVDIVKTNKQKDGILIEELGEVSKHKAATKPTTNEEGESCARVQSKSPPEKSQGCHPESSSAPSSPDALHTDTADPVLGCSEESKVRRTACMYGANCYRRNPLHFQHFSHPGDSDYGEVHGTDEGVIGDRPECPYGASCYRKNPQHKMEYRHSALPARVALDEDDDDVGQPSDDEDEEDYEPTDEDSDWHPGKDDEEQEDVDELLKEAKSSLHLKH", "length": 499 }, "evidence": [ { "id": "A0A8V0Z417", "url": "https://omabrowser.org/oma/group/A0A8V0Z417/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "site of double-strand break", "id": "GO:0035861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "DNA-(apurinic or apyrimidinic site) endonuclease activity", "id": "GO:0003906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003906", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "3'-5' exonuclease activity", "id": "GO:0008408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "poly-ADP-D-ribose binding", "id": "GO:0072572", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072572", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "ADP-D-ribose modification-dependent protein binding", "id": "GO:0160002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160002", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "histone chaperone activity", "id": "GO:0140713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140713", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "single strand break repair", "id": "GO:0000012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z417", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z417" } ], "pmid": "" }, { "name": "protein localization to chromatin", "id": 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"locus": { "chromosome": "3", "start_pos": 30543253, "end_pos": 30548054, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019832", "url": "https://www.ensembl.org/id/ENSGALG00010019832" } ] } } ], "crossref": [ { "id": "A0A8V0Z4Y8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4Y8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000027871", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000027871", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421448", "url": "https://www.ncbi.nlm.nih.gov/gene/421448", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "423770", "url": "https://www.iedb.org/epitope/423770", "database": "IEDB", "categories": [ "Other" ] }, { "id": "IPR009511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:421448", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421448", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCQQVLM", "url": "https://omabrowser.org/oma/group/KCQQVLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3Q2TW97", "url": "https://www.orthodb.org/?gene=A0A3Q2TW97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4Y8", "url": "https://www.orthodb.org/?gene=A0A8V0Z4Y8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15681", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15681", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15681:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15681:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2TW97", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TW97-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TW97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSLRKGGWELESRAGSAPWRPWSWECGVPGSSRAQPRCPPFWDSELWDSELWHTATGTGGGKPERFETFLPPEMPNKGRETAPRMQLFRYRNPLPTGAHNESIRLGVRMCRVVPPVLPPPTADGDVIKKPPSVGLASKKCQQVLVELEGVLQHLEAMFSLTLVPRVLILLGGNAVSPKELYELNLEGICVGSAEKSLKTTSCVRKLFHSLFIADVFSELKALPITGTVVMLQGHRNCGAEWFRPKLNYKVPTRGRKLTINLSCDGDVDISASAQTVTSAWEDYIWFQAPVTLKGFHE", "length": 298, "header": "tr|A0A8V0Z4Y8-1|A0A8V0Z4Y8_CHICK Isoform 1 of MAD2L1 binding protein OS=Gallus gallus OX=9031 GN=MAD2L1BP PE=4 SV=1 CANONICAL=A0A8V0Z4Y8-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2TW97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y8/entry#A0A3Q2TW97-1", "sequence": { "sequence": "MAALGGTESPGVMAAPGSQASPLLTAETPSALERGRSGRRSRRSAPAALSPAVSVVFPGAVSRESCCRFACELLKHVLHQRHQLPLPYEQLAYFCRRAAQDGDVIKKPPSVGLASKKCQQVLVELEGVLQHLEAMFSLTLVPRVLILLGGNAVSPKELYELNLEGICVGSAEKSLKTTSCVRKLFHSLFIADVFSELKALPITGTVVMLQGHRNCGAEWFRPKLNYKVPTRGRKLTINLSCDGDVDISASAQTVTSAWEDYIWFQAPVTLKGFHE", "length": 275, "header": "tr|A0A3Q2TW97-1|A0A8V0Z4Y8_CHICK Computationally mapped isoform of MAD2L1 binding protein OS=Gallus gallus OX=9031 GN=MAD2L1BP PE=4 SV=1 CANONICAL=A0A8V0Z4Y8-1" }, "locus": { "chromosome": "3", "start_pos": 30546998, "end_pos": 30545869, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047895.1", "url": "https://www.ensembl.org/id/ENSGALT00010047895.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028301.1", "url": "https://www.ensembl.org/id/ENSGALP00010028301.1" } ] } }, { "isoform_ac": "A0A8V0Z4Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y8/entry#A0A8V0Z4Y8-1", "sequence": { "sequence": "MDSLRKGGWELESRAGSAPWRPWSWECGVPGSSRAQPRCPPFWDSELWDSELWHTATGTGGGKPERFETFLPPEMPNKGRETAPRMQLFRYRNPLPTGAHNESIRLGVRMCRVVPPVLPPPTADGDVIKKPPSVGLASKKCQQVLVELEGVLQHLEAMFSLTLVPRVLILLGGNAVSPKELYELNLEGICVGSAEKSLKTTSCVRKLFHSLFIADVFSELKALPITGTVVMLQGHRNCGAEWFRPKLNYKVPTRGRKLTINLSCDGDVDISASAQTVTSAWEDYIWFQAPVTLKGFHE", "length": 298, "header": "tr|A0A8V0Z4Y8-1|A0A8V0Z4Y8_CHICK Isoform 1 of MAD2L1 binding protein OS=Gallus gallus OX=9031 GN=MAD2L1BP PE=4 SV=1 CANONICAL=A0A8V0Z4Y8-1" }, "locus": { "chromosome": "3", "start_pos": 30547917, "end_pos": 30545869, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047892.1", "url": "https://www.ensembl.org/id/ENSGALT00010047892.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028299.1", "url": "https://www.ensembl.org/id/ENSGALP00010028299.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:421448", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421448", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0K1L2-1", "protein_name": "MAD2L1 binding protein", "gene_name": "MAD2L1BP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAPEPEVQSPVAVSGLEWCEKSEETHDPQIELLETTSAQEPPNPSEPLRPRDCMVPVVFPGPVSQEGCCRFTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEDMVKKKPRATAEASNRKCQQTLVELESVLSHLEGLFARTLVPRVLILLGGNALSPKEFYELDLSRLAPNSMDPSLSTAACLRRLFRAIFMADAFSELQVPPLMGTIVMAQGHRDCGEDWFRPKLNYRVPSRGHKLTVTLSCGQPAIPTTAWEDYIWFQAPVTLKGFHE", "length": 274 }, "evidence": [ { "id": "A0A8V0Z4Y8", "url": "https://omabrowser.org/oma/group/A0A8V0Z4Y8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IL35-1", "protein_name": "MAD2L1-binding protein", "gene_name": "Mad2l1bp", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAPRPEFLSEPAPVAVPDLDWYEKPEETHAPQIDPETAITPPQEPSNPPEPFCPRDLVPVVFPGPVSQEGCCQFTCELLKHIMYQRQQLPLPYEQLKNFYRKSPQAEATVRKKPRITTEVSSKKCQQTLAELESVLSHLEDFFTRTLVPRVLILLGGNALSPKEFYELDLSRLAPFSVDESLNTAACLRRLFRAIFMADAFSELQAPPLMGTIVMVQGHRDCGEDWFRPKLNYRVPSRGHKLTVTLSCGRPSIPAMASEDYIWFQAPVTLKGFHE", "length": 276 }, "evidence": [ { "id": "A0A8V0Z4Y8", "url": "https://omabrowser.org/oma/group/A0A8V0Z4Y8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q15013-1", "protein_name": "MAD2L1-binding protein", "gene_name": "MAD2L1BP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPEAEVLSSAAVPDLEWYEKSEETHASQIELLETSSTQEPLNASEAFCPRDCMVPVVFPGPVSQEGCCQFTCELLKHIMYQRQQLPLPYEQLKHFYRKPSPQAEEMLKKKPRATTEVSSRKCQQALAELESVLSHLEDFFARTLVPRVLILLGGNALSPKEFYELDLSLLAPYSVDQSLSTAACLRRLFRAIFMADAFSELQAPPLMGTVVMAQGHRNCGEDWFRPKLNYRVPSRGHKLTVTLSCGRPSIRTTAWEDYIWFQAPVTFKGFRE", "length": 274 }, "evidence": [ { "id": "A0A8V0Z4Y8", "url": "https://omabrowser.org/oma/group/A0A8V0Z4Y8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DCX1-1", "protein_name": "MAD2L1-binding protein", "gene_name": "Mad2l1bp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASGEEDMSELSPAAAPNLDWYEKPEETHAPEVDLETVIPPAQEPSNPAEPFCPRDLVPVVFPGPVSQEDCCQFTCELLKHILYQRHQLPLPYEQLKHFYRKVPQAEDTARKKAWLATEARNRKCQQALAELESVLSHLRDFFARTLVPQVLILLGGNALSPKEFYELDLSRLAPFGVDQGLNTAACLRRLFRAIFLADPFSELQTPPLMGTIVMVQGHRDCGEDWFQPKLNYRVPSRGHKLTVTLSCGRPSVPAMASEDYIWFQAPVTLKGFHE", "length": 276 }, "evidence": [ { "id": "A0A8V0Z4Y8", "url": "https://omabrowser.org/oma/group/A0A8V0Z4Y8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y8" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y8" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of exit from mitosis", "id": "GO:0007096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007096", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y8" } ], "pmid": "" }, { "name": "deactivation of mitotic spindle assembly checkpoint", "id": "GO:1902426", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902426", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 261, "end_pos": 263 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z375-1", "uniprot_ac": "A0A8V0Z375", "uniprot_id": "A0A8V0Z375_CHICK", "mass": { "chemical_mass": 46530.0, "monoisotopic_mass": 46530.0 }, "refseq": {}, "gene_names": [ { "name": "CYTH3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z375", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375" } ] } ], "protein_names": [ { "name": "Cytohesin 3", "type": "synonym", "evidence": [ { "id": "A0A8V0Z375", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z375", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYTH3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375", "locus": { "chromosome": "14", "start_pos": 8919999, "end_pos": 8869023, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019239", "url": "https://www.ensembl.org/id/ENSGALG00010019239" } ] } } ], "crossref": [ { "id": "A0A8V0Z375", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z375", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000007149", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000007149", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00171", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00171", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01252", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01252", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416626", "url": "https://www.ncbi.nlm.nih.gov/gene/416626", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LLAKICW", "url": "https://omabrowser.org/oma/group/LLAKICW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAL6", "url": "https://www.orthodb.org/?gene=A0A8V0ZAL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF320", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF320", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01369", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01369", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A3Q2U511", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U511", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2U511-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2U511-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z375", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z375-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z379", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z379", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z379-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z379-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z384", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z384", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z384-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z384-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKVDLNTSGSLPDDLSIEEREELLNIRRRKKELIDDIERLKFEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQNTAEDIAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTVERFISMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASISRDPFYDMLATRKRRIANKK", "length": 399, "header": "tr|A0A8V0Z375-1|A0A8V0Z375_CHICK Isoform 1 of Cytohesin 3 OS=Gallus gallus OX=9031 GN=CYTH3 PE=4 SV=1 CANONICAL=A0A8V0Z375-1" }, "isoforms": [ { "isoform_ac": "A0A3Q2U511-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375/entry#A0A3Q2U511-1", "sequence": { "sequence": "MVPDDLSIEEREELLNIRRRKKELIDDIERLKFEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQNTAEDIAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTVERFISMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASISRDPFYDMLATRKRRIANKK", "length": 389, "header": "tr|A0A3Q2U511-1|A0A8V0Z375_CHICK Computationally mapped isoform of Cytohesin 3 OS=Gallus gallus OX=9031 GN=CYTH3 PE=4 SV=1 CANONICAL=A0A8V0Z375-1" }, "locus": { "chromosome": "14", "start_pos": 8916656, "end_pos": 8890160, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046508.1", "url": "https://www.ensembl.org/id/ENSGALT00010046508.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027688.1", "url": "https://www.ensembl.org/id/ENSGALP00010027688.1" } ] } }, { "isoform_ac": "A0A8V0Z375-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375/entry#A0A8V0Z375-1", "sequence": { "sequence": "MDKVDLNTSGSLPDDLSIEEREELLNIRRRKKELIDDIERLKFEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQNTAEDIAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTVERFISMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASISRDPFYDMLATRKRRIANKK", "length": 399, "header": "tr|A0A8V0Z375-1|A0A8V0Z375_CHICK Isoform 1 of Cytohesin 3 OS=Gallus gallus OX=9031 GN=CYTH3 PE=4 SV=1 CANONICAL=A0A8V0Z375-1" }, "locus": { "chromosome": "14", "start_pos": 8916656, "end_pos": 8897083, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046505.1", "url": "https://www.ensembl.org/id/ENSGALT00010046505.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027686.1", "url": "https://www.ensembl.org/id/ENSGALP00010027686.1" } ] } }, { "isoform_ac": "A0A8V0Z379-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375/entry#A0A8V0Z379-1", "sequence": { "sequence": "MPDDLSIEEREELLNIRRRKKELIDDIERLKFEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQNTAEDIAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTVERFISMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASISRDPFYDMLATRKRRIANKK", "length": 388, "header": "tr|A0A8V0Z379-1|A0A8V0Z379_CHICK Computationally mapped isoform of Cytohesin 3 OS=Gallus gallus OX=9031 GN=CYTH3 PE=4 SV=1 CANONICAL=A0A8V0Z375-1" }, "locus": { "chromosome": "14", "start_pos": 8916656, "end_pos": 8877587, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046515.1", "url": "https://www.ensembl.org/id/ENSGALT00010046515.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027691.1", "url": "https://www.ensembl.org/id/ENSGALP00010027691.1" } ] } }, { "isoform_ac": "A0A8V0Z384-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375/entry#A0A8V0Z384-1", "sequence": { "sequence": "MDEEGGGGGVPDDLSIEEREELLNIRRRKKELIDDIERLKFEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQNTAEDIAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTVERFISMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASISRDPFYDMLATRKRRIANKK", "length": 398, "header": "tr|A0A8V0Z384-1|A0A8V0Z384_CHICK Computationally mapped isoform of Cytohesin 3 OS=Gallus gallus OX=9031 GN=CYTH3 PE=4 SV=1 CANONICAL=A0A8V0Z375-1" }, "locus": { "chromosome": "14", "start_pos": 8916656, "end_pos": 8869223, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046521.1", "url": "https://www.ensembl.org/id/ENSGALT00010046521.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027696.1", "url": "https://www.ensembl.org/id/ENSGALP00010027696.1" } ] } }, { "isoform_ac": "A0A8V0ZAL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375/entry#A0A8V0ZAL6-1", "sequence": { "sequence": "MVPCSRSMEFIDSVPDDLSIEEREELLNIRRRKKELIDDIERLKFEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQNTAEDIAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTVERFISMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASISRDPFYDMLATRKRRIANKK", "length": 401, "header": "tr|A0A8V0ZAL6-1|A0A8V0Z375_CHICK Computationally mapped isoform of Cytohesin 3 OS=Gallus gallus OX=9031 GN=CYTH3 PE=4 SV=1 CANONICAL=A0A8V0Z375-1" }, "locus": { "chromosome": "14", "start_pos": 8916656, "end_pos": 8877380, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046517.1", "url": "https://www.ensembl.org/id/ENSGALT00010046517.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027694.1", "url": "https://www.ensembl.org/id/ENSGALP00010027694.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LEK2-1", "protein_name": "Cytohesin-3 isoform X1", "gene_name": "Cyth3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDEGGGGEGGSVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK", "length": 399 }, "evidence": [ { "id": "A0A8V0Z375", "url": "https://omabrowser.org/oma/group/A0A8V0Z375/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08967-1", "protein_name": "Cytohesin-3", "gene_name": "Cyth3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEGGGGEGGSVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK", "length": 399 }, "evidence": [ { "id": "A0A8V0Z375", "url": "https://omabrowser.org/oma/group/A0A8V0Z375/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O43739-1", "protein_name": "Cytohesin-3", "gene_name": "CYTH3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK", "length": 400 }, "evidence": [ { "id": "A0A8V0Z375", "url": "https://omabrowser.org/oma/group/A0A8V0Z375/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97696-1", "protein_name": "Cytohesin-3", "gene_name": "Cyth3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEGGGGEGGSVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK", "length": 400 }, "evidence": [ { "id": "A0A8V0Z375", "url": "https://omabrowser.org/oma/group/A0A8V0Z375/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z375", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": 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"GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z375", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z375", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375" } ], "pmid": "" }, { "name": "phosphatidylinositol-3,4,5-trisphosphate binding", "id": "GO:0005547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005547", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z375", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of ARF protein signal transduction", "id": "GO:0032012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032012", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z375", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z375", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375" } ], "pmid": "" }, { "name": "Golgi vesicle transport", "id": "GO:0048193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048193", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z375", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z375" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": 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"glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 54, "end_pos": 56 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z523-1", "uniprot_ac": "A0A8V0Z523", "uniprot_id": "A0A8V0Z523_CHICK", "mass": { "chemical_mass": 14740.0, "monoisotopic_mass": 14740.0 }, "refseq": { "ac": "XP_046756197", "name": "chemokine-like protein TAFA-1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756197" }, "gene_names": [ { "name": "FAM19A1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523" } ] }, { "name": "FAM19A1", "type": "synonym", "evidence": [ { "id": "XP_046756197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756197" } ] } ], "protein_names": [ { "name": "TAFA chemokine like family member 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z523", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523/entry#names_and_taxonomy" } ] }, { "name": "chemokine-like protein TAFA-1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_046756197", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756197" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052543.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046756197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756197" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z523", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM19A1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z523", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z523", "database": "AlphaFoldDB", "categories": [] }, { "id": "416089", "url": "https://www.ncbi.nlm.nih.gov/gene/416089", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416089", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416089", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQGSLQQ", "url": "https://omabrowser.org/oma/group/CQGSLQQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z523", "url": "https://www.orthodb.org/?gene=A0A8V0Z523", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z534", "url": "https://www.orthodb.org/?gene=A0A8V0Z534", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z538", "url": "https://www.orthodb.org/?gene=A0A8V0Z538", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAV8", "url": "https://www.orthodb.org/?gene=A0A8V0ZAV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAY4", "url": "https://www.orthodb.org/?gene=A0A8V0ZAY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBP8", "url": "https://www.orthodb.org/?gene=A0A8V0ZBP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCD7", "url": "https://www.orthodb.org/?gene=A0A8V0ZCD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCE3", "url": "https://www.orthodb.org/?gene=A0A8V0ZCE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZIC1", "url": "https://www.orthodb.org/?gene=A0A8V0ZIC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31770", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31770", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31770:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31770:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046756197", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046756197", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z523", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z523-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z534", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z534", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z534-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z534-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z538", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z538", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z538-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z538-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAV8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBP8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCD7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCE3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZIC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVVSAMSWVLYLWISACAMLLCQGSLHHTFQQHHLHRPGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 132, "header": "tr|A0A8V0Z523-1|A0A8V0Z523_CHICK Isoform 1 of TAFA chemokine like family member 1 OS=Gallus gallus OX=9031 GN=FAM19A1 PE=3 SV=1 CANONICAL=A0A8V0Z523-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z523-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523/entry#A0A8V0Z523-1", "sequence": { "sequence": "MAVVSAMSWVLYLWISACAMLLCQGSLHHTFQQHHLHRPGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 132, "header": "tr|A0A8V0Z523-1|A0A8V0Z523_CHICK Isoform 1 of TAFA chemokine like family member 1 OS=Gallus gallus OX=9031 GN=FAM19A1 PE=3 SV=1 CANONICAL=A0A8V0Z523-1" }, "locus": { "chromosome": "12", "start_pos": 15318450, "end_pos": 15124126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048003.1", "url": "https://www.ensembl.org/id/ENSGALT00010048003.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028335.1", "url": "https://www.ensembl.org/id/ENSGALP00010028335.1" } ] } }, { "isoform_ac": "A0A8V0Z534-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523/entry#A0A8V0Z534-1", "sequence": { "sequence": "MNTNRVLCSWLDYSENGSGLCNVLGPVFVDKCLCNAALSGIPPSHFPAASPAQTRKDSFCESDFPVGLNLQNSEDSCCDKDISAACHHKVQASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 138, "header": "tr|A0A8V0Z534-1|A0A8V0Z534_CHICK Computationally mapped isoform of TAFA chemokine like family member 1 OS=Gallus gallus OX=9031 GN=FAM19A1 PE=3 SV=1 CANONICAL=A0A8V0Z523-1" }, "locus": { "chromosome": "12", "start_pos": 15318450, "end_pos": 15122034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048017.1", "url": "https://www.ensembl.org/id/ENSGALT00010048017.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028345.1", "url": "https://www.ensembl.org/id/ENSGALP00010028345.1" } ] } }, { "isoform_ac": "A0A8V0Z538-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523/entry#A0A8V0Z538-1", "sequence": { "sequence": "MAVVSAMSWVLYLWISACAMLLCQGSLHHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVQASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 133, "header": "tr|A0A8V0Z538-1|A0A8V0Z538_CHICK Computationally mapped isoform of TAFA chemokine like family member 1 OS=Gallus gallus OX=9031 GN=FAM19A1 PE=3 SV=1 CANONICAL=A0A8V0Z523-1" }, "locus": { "chromosome": "12", "start_pos": 15318450, "end_pos": 15124126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048028.1", "url": "https://www.ensembl.org/id/ENSGALT00010048028.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028350.1", "url": "https://www.ensembl.org/id/ENSGALP00010028350.1" } ] } }, { "isoform_ac": "A0A8V0ZAV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523/entry#A0A8V0ZAV8-1", "sequence": { "sequence": "MPLWKSLIACSGCPSMSALGDRNKVLFAFPRMAVVSAMSWVLYLWISACAMLLCQGSLHHTFQQHHLHRPGKTLSVNQIFQWEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 176, "header": "tr|A0A8V0ZAV8-1|A0A8V0Z523_CHICK Computationally mapped isoform of TAFA chemokine like family member 1 OS=Gallus gallus OX=9031 GN=FAM19A1 PE=3 SV=1 CANONICAL=A0A8V0Z523-1" }, "locus": { "chromosome": "12", "start_pos": 15318450, "end_pos": 15123299, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047997.1", "url": "https://www.ensembl.org/id/ENSGALT00010047997.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028332.1", "url": "https://www.ensembl.org/id/ENSGALP00010028332.1" } ] } }, { "isoform_ac": "A0A8V0ZAY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523/entry#A0A8V0ZAY4-1", "sequence": { "sequence": "MSQEELANANQLLLLGPRCKKQNICLPNTGTVKTRPPLNKEEWHLKGKTLSVNQIFQWEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 152, "header": "tr|A0A8V0ZAY4-1|A0A8V0Z523_CHICK Computationally mapped isoform of TAFA chemokine like family member 1 OS=Gallus gallus OX=9031 GN=FAM19A1 PE=3 SV=1 CANONICAL=A0A8V0Z523-1" }, "locus": { "chromosome": "12", "start_pos": 15318450, "end_pos": 15084376, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048042.1", "url": "https://www.ensembl.org/id/ENSGALT00010048042.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028357.1", "url": "https://www.ensembl.org/id/ENSGALP00010028357.1" } ] } }, { "isoform_ac": "A0A8V0ZBP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523/entry#A0A8V0ZBP8-1", "sequence": { "sequence": "MNTNRVLCSWLDYSGKTLSVNQIFQWEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 120, "header": "tr|A0A8V0ZBP8-1|A0A8V0Z523_CHICK Computationally mapped isoform of TAFA chemokine like family member 1 OS=Gallus gallus OX=9031 GN=FAM19A1 PE=3 SV=1 CANONICAL=A0A8V0Z523-1" }, "locus": { "chromosome": "12", "start_pos": 15318450, "end_pos": 15122034, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048007.1", "url": "https://www.ensembl.org/id/ENSGALT00010048007.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028339.1", "url": "https://www.ensembl.org/id/ENSGALP00010028339.1" } ] } }, { "isoform_ac": "A0A8V0ZCD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523/entry#A0A8V0ZCD7-1", "sequence": { "sequence": "MAVVSAMSWVLYLWISACAMLLCQGSLHHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 133, "header": "tr|A0A8V0ZCD7-1|A0A8V0Z523_CHICK Computationally mapped isoform of TAFA chemokine like family member 1 OS=Gallus gallus OX=9031 GN=FAM19A1 PE=3 SV=1 CANONICAL=A0A8V0Z523-1" }, "locus": { "chromosome": "12", "start_pos": 15318450, "end_pos": 15124126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048023.1", "url": "https://www.ensembl.org/id/ENSGALT00010048023.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028348.1", "url": "https://www.ensembl.org/id/ENSGALP00010028348.1" } ] } }, { "isoform_ac": "A0A8V0ZCE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523/entry#A0A8V0ZCE3-1", "sequence": { "sequence": "WLSADWRRLPARQLSGQAAGTGPRCKKQNICLPNTGTVKTRPPLNKEEWHLKGKTLSVNQIFQWEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 158, "header": "tr|A0A8V0ZCE3-1|A0A8V0Z523_CHICK Computationally mapped isoform of TAFA chemokine like family member 1 OS=Gallus gallus OX=9031 GN=FAM19A1 PE=3 SV=1 CANONICAL=A0A8V0Z523-1" }, "locus": { "chromosome": "12", "start_pos": 15318450, "end_pos": 15108651, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048033.1", "url": "https://www.ensembl.org/id/ENSGALT00010048033.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028353.1", "url": "https://www.ensembl.org/id/ENSGALP00010028353.1" } ] } }, { "isoform_ac": "A0A8V0ZIC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523/entry#A0A8V0ZIC1-1", "sequence": { "sequence": "MAVVSAMSWVLYLWISACAMLLCQGSLHHTFQQHHLHRPGKTLSVNQIFQWEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 145, "header": "tr|A0A8V0ZIC1-1|A0A8V0Z523_CHICK Computationally mapped isoform of TAFA chemokine like family member 1 OS=Gallus gallus OX=9031 GN=FAM19A1 PE=3 SV=1 CANONICAL=A0A8V0Z523-1" }, "locus": { "chromosome": "12", "start_pos": 15318450, "end_pos": 15124126, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048011.1", "url": "https://www.ensembl.org/id/ENSGALT00010048011.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028341.1", "url": "https://www.ensembl.org/id/ENSGALP00010028341.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416089", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416089", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MCT3-1", "protein_name": "Chemokine-like protein TAFA-1", "gene_name": "Tafa1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAMVSAMSWVLYLWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 133 }, "evidence": [ { "id": "A0A8V0Z523", "url": "https://omabrowser.org/oma/group/A0A8V0Z523/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8I5ZYE4-1", "protein_name": "TAFA chemokine like family member 1", "gene_name": "Tafa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTMVSAMSWVLYLWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 133 }, "evidence": [ { "id": "A0A8V0Z523", "url": "https://omabrowser.org/oma/group/A0A8V0Z523/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9SHX0-1", "protein_name": "TAFA chemokine like family member 1", "gene_name": "TAFA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAMVSAMSWVLYLWISACAVLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 133 }, "evidence": [ { "id": "A0A8V0Z523", "url": "https://omabrowser.org/oma/group/A0A8V0Z523/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7TPG8-1", "protein_name": "Chemokine-like protein TAFA-1", "gene_name": "Tafa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMVSAMSWALYLWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 133 }, "evidence": [ { "id": "A0A8V0Z523", "url": "https://omabrowser.org/oma/group/A0A8V0Z523/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z5A9-1", "protein_name": "Chemokine-like protein TAFA-1", "gene_name": "TAFA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMVSAMSWVLYLWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT", "length": 133 }, "evidence": [ { "id": "A0A8V0Z523", "url": "https://omabrowser.org/oma/group/A0A8V0Z523/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuroblast differentiation", "id": "GO:0014016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014016", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z523", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523" } ], "pmid": "" }, { "name": "regulation of neuroblast proliferation", "id": "GO:1902692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902692", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z523", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z523", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z523", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "receptor ligand activity", "id": "GO:0048018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048018", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z523", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z523" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRV6-1", "uniprot_ac": "A0A8V0ZRV6", "uniprot_id": "A0A8V0ZRV6_CHICK", "mass": { "chemical_mass": 33207.0, "monoisotopic_mass": 33207.0 }, "refseq": {}, "gene_names": [ { "name": "RPUSD3", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6" } ] } ], "protein_names": [ { "name": "RNA pseudouridine synthase D3", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RPUSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6", "locus": { "chromosome": "12", "start_pos": 11671076, "end_pos": 11673982, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021646", "url": "https://www.ensembl.org/id/ENSGALG00010021646" } ] } } ], "crossref": [ { "id": "A0A8V0ZRV6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRV6", "database": "AlphaFoldDB", "categories": [] }, { "id": "101748025", "url": "https://www.ncbi.nlm.nih.gov/gene/101748025", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101748025", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748025", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PPAWYHL", "url": "https://omabrowser.org/oma/group/PPAWYHL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZDY4", "url": "https://www.orthodb.org/?gene=A0A8V0ZDY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZL99", "url": "https://www.orthodb.org/?gene=A0A8V0ZL99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRT4", "url": "https://www.orthodb.org/?gene=A0A8V0ZRT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRV6", "url": "https://www.orthodb.org/?gene=A0A8V0ZRV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRW2", "url": "https://www.orthodb.org/?gene=A0A8V0ZRW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21600", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21600", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21600:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21600:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00849", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00849", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZDY4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZDY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL99", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZL99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZL99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRT4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRW2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SLPSVPAARGPPRDAIAACRDTERGDPRKGRPLGPEAVLGLLEASVVHREGALLALSKPADLPVLGRPGELSLTALLPALRRRLGLPAELHVVKAPARECSGLVLLSACPRVTEQLQRSFTAARRRAQFPATYSAVTVGIPAEAEGEISVGLCWQQKGDAAAVVAVPSPGRRSVARGEVKCTLTRYRLLGAAGGCALLQLQPRTAFPEQLQVHLTLLLCPALGDHRHASRVGTVLGEPFLLPPQETPTPCTQVLDAELMSRLQLSPHHRLPLHLHLQQLVLPHTVLSAPPPPHFLRTLRLLGLPSPPLPPH", "length": 311, "header": "tr|A0A8V0ZRV6-1|A0A8V0ZRV6_CHICK Isoform 1 of RNA pseudouridine synthase D3 OS=Gallus gallus OX=9031 GN=RPUSD3 PE=4 SV=1 CANONICAL=A0A8V0ZRV6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZDY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6/entry#A0A8V0ZDY4-1", "sequence": { "sequence": "MAGCGGAARVAARVGRGARTAGKGRPLGPEAVLGLLEASVVHREGALLALSKPADLPVLGRPGELSLTALLPALRRRLGLPAELHVVKAPARECSGLVLLSACPRVTEQLQRSFTAARRRAQFPATYSAVTVGIPAEAEGEISVGLCWQQKGDAAAVVAVPSPGRRSVARGEVKCTLTRYRLLGAAGGCALLQLQPRTAFPEQLQVHLTLLLCPALGDHRHASRVGTVLGEPFLLPPQETPTPCTQVLDAELMSRLQLSPHHRLPLHLHLQQLVLPHTVLSAPPPPHFLRTLRLLGLPSPPLPPH", "length": 305, "header": "tr|A0A8V0ZDY4-1|A0A8V0ZRV6_CHICK Computationally mapped isoform of RNA pseudouridine synthase D3 OS=Gallus gallus OX=9031 GN=RPUSD3 PE=4 SV=1 CANONICAL=A0A8V0ZRV6-1" }, "locus": { "chromosome": "12", "start_pos": 11672770, "end_pos": 11671095, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052593.1", "url": "https://www.ensembl.org/id/ENSGALT00010052593.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031499.1", "url": "https://www.ensembl.org/id/ENSGALP00010031499.1" } ] } }, { "isoform_ac": "A0A8V0ZL99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6/entry#A0A8V0ZL99-1", "sequence": { "sequence": "MTAASVLTASGRRPVYTPGGPALWKGRPLGPEAVLGLLEASVVHREGALLALSKPADLPVLGRPGELSLTALLPALRRRLGLPAELHVVKAPARECSGLVLLSACPRVTEQLQRSFTAARRRAQFPATYSAVTVGIPAEAEGEISVGLCWQQKGDAAAVVAVPSPGRRSVARGEVKCTLTRYRLLGAAGGCALLQLQPRTAFPEQLQVHLTLLLCPALGDHRHASRVGTVLGEPFLLPPQETPTPCTQVLDAELMSRLQLSPHHRLPLHLHLQQLVLPHTVLSAPPPPHFLRTLRLLGLPSPPLPPH", "length": 307, "header": "tr|A0A8V0ZL99-1|A0A8V0ZRV6_CHICK Computationally mapped isoform of RNA pseudouridine synthase D3 OS=Gallus gallus OX=9031 GN=RPUSD3 PE=4 SV=1 CANONICAL=A0A8V0ZRV6-1" }, "locus": { "chromosome": "12", "start_pos": 11672897, "end_pos": 11671095, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052597.1", "url": "https://www.ensembl.org/id/ENSGALT00010052597.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031503.1", "url": "https://www.ensembl.org/id/ENSGALP00010031503.1" } ] } }, { "isoform_ac": "A0A8V0ZRT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6/entry#A0A8V0ZRT4-1", "sequence": { "sequence": "MKGRPLGPEAVLGLLEASVVHREGALLALSKPADLPVLGRPGELSLTALLPALRRRLGLPAELHVVKAPARECSGLVLLSACPRVTEQLQRSFTAARRRAQFPATYSAVTVGIPAEAEGEISVGLCWQQKGDAAAVVAVPSPGRRSVARGEVKCTLTRYRLLGAAGGCALLQLQPRTAFPEQLQVHLTLLLCPALGDHRHASRVGTVLGEPFLLPPQETPTPCTQVLDAELMSRLQLSPHHRLPLHLHLQQLVLPHTVLSAPPPPHFLRTLRLLGLPSPPLPPH", "length": 284, "header": "tr|A0A8V0ZRT4-1|A0A8V0ZRT4_CHICK Computationally mapped isoform of RNA pseudouridine synthase D3 OS=Gallus gallus OX=9031 GN=RPUSD3 PE=4 SV=1 CANONICAL=A0A8V0ZRV6-1" }, "locus": { "chromosome": "12", "start_pos": 11672612, "end_pos": 11671095, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052579.1", "url": "https://www.ensembl.org/id/ENSGALT00010052579.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031485.1", "url": "https://www.ensembl.org/id/ENSGALP00010031485.1" } ] } }, { "isoform_ac": "A0A8V0ZRV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6/entry#A0A8V0ZRV6-1", "sequence": { "sequence": "SLPSVPAARGPPRDAIAACRDTERGDPRKGRPLGPEAVLGLLEASVVHREGALLALSKPADLPVLGRPGELSLTALLPALRRRLGLPAELHVVKAPARECSGLVLLSACPRVTEQLQRSFTAARRRAQFPATYSAVTVGIPAEAEGEISVGLCWQQKGDAAAVVAVPSPGRRSVARGEVKCTLTRYRLLGAAGGCALLQLQPRTAFPEQLQVHLTLLLCPALGDHRHASRVGTVLGEPFLLPPQETPTPCTQVLDAELMSRLQLSPHHRLPLHLHLQQLVLPHTVLSAPPPPHFLRTLRLLGLPSPPLPPH", "length": 311, "header": "tr|A0A8V0ZRV6-1|A0A8V0ZRV6_CHICK Isoform 1 of RNA pseudouridine synthase D3 OS=Gallus gallus OX=9031 GN=RPUSD3 PE=4 SV=1 CANONICAL=A0A8V0ZRV6-1" }, "locus": { "chromosome": "12", "start_pos": 11673178, "end_pos": 11671095, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052601.1", "url": "https://www.ensembl.org/id/ENSGALT00010052601.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031507.1", "url": "https://www.ensembl.org/id/ENSGALP00010031507.1" } ] } }, { "isoform_ac": "A0A8V0ZRW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6/entry#A0A8V0ZRW2-1", "sequence": { "sequence": "MLLRGKESRPSSEGRMLSRKGRPLGPEAVLGLLEASVVHREGALLALSKPADLPVLGRPGELSLTALLPALRRRLGLPAELHVVKAPARECSGLVLLSACPRVTEQLQRSFTAARRRAQFPATYSAVTVGIPAEAEGEISVGLCWQQKGDAAAVVAVPSPGRRSVARGEVKCTLTRYRLLGAAGGCALLQLQPRTAFPEQLQVHLTLLLCPALGDHRHASRVGTVLGEPFLLPPQETPTPCTQVLDAELMSRLQLSPHHRLPLHLHLQQLVLPHTVLSAPPPPHFLRTLRLLGLPSPPLPPH", "length": 302, "header": "tr|A0A8V0ZRW2-1|A0A8V0ZRW2_CHICK Computationally mapped isoform of RNA pseudouridine synthase D3 OS=Gallus gallus OX=9031 GN=RPUSD3 PE=4 SV=1 CANONICAL=A0A8V0ZRV6-1" }, "locus": { "chromosome": "12", "start_pos": 11673571, "end_pos": 11671095, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052606.1", "url": "https://www.ensembl.org/id/ENSGALT00010052606.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031512.1", "url": "https://www.ensembl.org/id/ENSGALP00010031512.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 137, "start_aa": "Thr", "end_pos": 137, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr137", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101748025", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101748025", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A6T2-1", "protein_name": "RNA pseudouridine synthase D3", "gene_name": "Rpusd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEALRALRSVSVVWRPGLGSSARRRDAGFGTEARKRKDLVEDQPFPGLLRAENLGLEELAQVLRAAVVDQKGRPGELTLLSVLPWLSQALGLEHQELQVVRAPGKEASGLVLLSSCPQTTSHLQKFFTHSRRAQRPTATYCAITDGVPEPSEGTVHIALRLERMDGIDLAVPVTSPSRKDIQEGVKRTLSHFHVTATGCGCALVQLQPLTVFPSQLQVHMALQLCPILGDHTYAARVGSVLGQRFLWPAETTKPQRQVLDEALLRYLHLSPSQVAQMPLHLHLHRLLLPGTRPRDPPSELLAPLPPYFSRTLQCLRLSQQ", "length": 320 }, "evidence": [ { "id": "A0A8V0ZRV6", "url": "https://omabrowser.org/oma/group/A0A8V0ZRV6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SQE3-1", "protein_name": "RNA pseudouridine synthase D3", "gene_name": "RPUSD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRTILTPEMGGYRVWGQVWGGCRQGLGICAVPKAAGFGTEARHQLQSRGSSKRLGSLGDKPFRRLLQPENLSREELVDVLREAVVDQKGPLVTLNKPQGLPVTGKPGELTLVSVLPELSQCLGLGERELQVVRASGKETSGLVLLSSCPQTASRLQKFFTHSQRARKPTATYCAVTDGIPAASEGKIQAALKMEHTDGASLVVPVKSPSRKDFLKGVKWTLSHFRVLASGSGCALVQLQPLTAFPSQLQVHMVLQLCPVLGDHKYSACVGTVLGQRFLLPAENTKPQRQVLDEALLSRLHLTPAQAAQLPLHIHLHRLHLPGTRPRDAPIELLAPLPSYFSRTLQCLGLQYQ", "length": 352 }, "evidence": [ { "id": "A0A8V0ZRV6", "url": "https://omabrowser.org/oma/group/A0A8V0ZRV6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q14AI6-1", "protein_name": "Mitochondrial mRNA pseudouridine synthase Rpusd3", "gene_name": "Rpusd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGALRVLRYVSMIWRPELGSCARQRDAGFGTEARRPSQPHRSSKHKDLVEDQPFPGLLRTENLGLEELAHVLRAAVVDQKGPLVTLNKPQGLPVTGRPGELTLLSVLPQLSQALGLEHQELQVVRAPGKEASGLVLLSSCPQTASRLQKFFIHSRRAQRPTATYCAVTDGIPEPSEGTVCMPLKMEQMNDVDLAVPVMSPSRKDIQEGVKRTLSRFHVMATGRGCALVQLQPLTVFPNQLQVHMALQLCPILGDHTYAARVGTVLGQRFLWPAETTKPQRQVLDEALLRHLRLSPSQVAQMPLHLHLHRLLLPGTGSRDPPSELLAPLPPYFSRTLQCLRLSQQ", "length": 344 }, "evidence": [ { "id": "A0A8V0ZRV6", "url": "https://omabrowser.org/oma/group/A0A8V0ZRV6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6P087-1", "protein_name": "Mitochondrial mRNA pseudouridine synthase RPUSD3", "gene_name": "RPUSD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAVLAREMDGRRVLGRFWSGWRRGLGVRPVPEDAGFGTEARHQRQPRGSCQRSGPLGDQPFAGLLPKNLSREELVDALRAAVVDRKGPLVTLNKPQGLPVTGKPGELTLFSVLPELSQSLGLREQELQVVRASGKESSGLVLLSSCPQTASRLQKYFTHARRAQRPTATYCAVTDGIPAASEGKIQAALKLEHIDGVNLTVPVKAPSRKDILEGVKKTLSHFRVVATGSGCALVQLQPLTVFSSQLQVHMVLQLCPVLGDHMYSARVGTVLGQRFLLPAENNKPQRQVLDEALLRRLHLTPSQAAQLPLHLHLHRLLLPGTRARDTPVELLAPLPPYFSRTLQCLGLRLQ", "length": 351 }, "evidence": [ { "id": "A0A8V0ZRV6", "url": "https://omabrowser.org/oma/group/A0A8V0ZRV6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "pseudouridine synthesis", "id": "GO:0001522", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001522", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6" } ], "pmid": "" }, { "name": "mRNA pseudouridine synthesis", "id": "GO:1990481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990481", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial translation", "id": "GO:0070131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070131", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6" } ], "pmid": "" }, { "name": "ribonucleoprotein granule", "id": "GO:0035770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035770", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRV6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV6" }, { "id": "PF00849", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00849" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pseudouridine synthase RsuA/RluA-like", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 214, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 137 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_052579.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046777335", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046777335" } ] }, { "annotation": "Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. 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"MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAAVSVQEESDLEKKRREAEALLQSMGLTTDSPIVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRRGPIKLGMAKITQVDFPPREIVTYTKETQTPVTAQPKEDEEEEDDVATPKPPVEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEEAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNSDYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA", "length": 612 }, "evidence": [ { "id": "A0A8V0ZRT5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P54703-1", "protein_name": "Cytoplasmic dynein 1 intermediate chain", "gene_name": "dicA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDRDQKKKELEQTKNEMRRKLEEYKERNRIMASKTTPTATTTSTLNTASTPSPPVAQEDFNSIMNSIDSMVPTQATPSSSSTISTSTHAESQKSNYIRPTLTIQSLVIEHDFPPKEIPMYSKGTQTMTDADTSNTNNTPELEAPNKNKTKYQLLQQQQQQQQQQQSSLNQDMQNLSIGTDSINGDGSSTSVANSANIDDDDKDEIEIPELDENEKKDILESDSFKSFFGRSSRVIERALCLDDSIDILVDYTISDENSKGTSKELKLLATLSDERWTKHRSITDISWSTKHPELVVSSYSANEAGSHDPDGVALVWSVNNYFQKPEYVFTCQSPVMTTFFSKFHSTLIVGGTYSGQIVIWDTRAEAKPVQKTPLSSVGHTHPVYSMAVVGSANANSLVSISTDAKLCSWNLENLSQPIETIELNSSNTNSANKAGGGGSGGGAPNMSIAVTSLVFPENELNHFYIGTEEGVICQAGRHGNRIVMNERYKGHFGPITSVDLHPSKGGADFSQYFLSSSTDWTCKLWSSKKETPLYSFEDYVDYVYDARWSPVHPSIFSTGDGSGTLSLWDLNQDLEAPIFRHKISNRSVNRLAWSHDGKRILVGDSGGSLSLFDSSEFSSPTSEEYSQFEDVMTKMVNKSRTSDSPLLGEGENQE", "length": 654 }, "evidence": [ { "id": "A0A8V0ZRT5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT5/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q13409-1", "protein_name": "Cytoplasmic dynein 1 intermediate chain 2", "gene_name": "DYNC1I2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREAEALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDPSVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA", "length": 638 }, "evidence": [ { "id": "A0A8V0ZRT5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q24246-11", "protein_name": "Cytoplasmic dynein 1 intermediate chain", "gene_name": "sw", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDRKAELERKKAKLAALREEKDRRRREKEIKDMEEAAGRIGGGAGIDKDQRKDLDEMLSSLGVAPVSEVLSSLSSVNSMTSDNSNTQTPDASLQATVNGQSGGKKQPLNLSVYNVQATNIPPKETLVYTKQTQTTSTGGGNGDVLSCHSSPLSGYMEDWWRPRKAHATDYYDEYNLNPGLEWEDEFTDDEESSLQNLGNGFTSKLPPGYLTHGLPTVKDVAPAITPLEIKKETEVKKEVNELSEEQKQMIILSENFQRFVVRAGRVIERALSENVDIYTDYIGGGDSEEANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFPELVVGSYHNNEESPNEPDGVVMVWNTKFKKSTPEDVFHCQSAVMSTCFAKFNPNLILGGTYSGQIVLWDNRVQKRTPIQRTPLSAAAHTHPVYCLQMVGTQNAHNVISISSDGKLCSWSLDMLSQPQDTLELQQRQSKAIAITSMAFPANEINSLVMGSEDGYVYSASRHGLRSGVNEVYERHLGPITGISTHYNQLSPDFGHLFLTSSIDWTIKLWSLKDTKPLYSFEDNSDYVMDVAWSPVHPALFAAVDGSGRLDLWNLNQDTEVPTASIVVAGAPALNRVSWTPSGLHVCIGDEAGKLYVYDVAENLAQPSRDEWSRFNTHLSEIKMNQSDEV", "length": 663 }, "evidence": [ { "id": "A0A8V0ZRT5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q62871-1", "protein_name": "Cytoplasmic dynein 1 intermediate chain 2", "gene_name": "Dync1i2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAAVSVQEESDLEKKRREAEALLQSMGLTTDSPIVFSEHWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDPSALQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVTAQPKEDEEEEDDVAAPKPPVEPEEEKILKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEEAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTVKLWSTKNNKPLYSFEDNSDYVYDVIGSPTHPALFACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINASRADAEEEAATRIPA", "length": 638 }, "evidence": [ { "id": "A0A8V0ZRT5", "url": "https://omabrowser.org/oma/group/A0A8V0ZRT5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT5" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT5" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT5" } ], "pmid": "" }, { "name": "cytoplasmic dynein complex", "id": "GO:0005868", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005868", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transport along microtubule", "id": "GO:0010970", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010970", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "dynein light chain binding", "id": "GO:0045503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045503", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT5" } ], "pmid": "" }, { "name": "dynein heavy chain binding", "id": "GO:0045504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045504", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRT5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 371, "end_pos": 373 }, { "start_pos": 565, "end_pos": 567 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRU2-1", "uniprot_ac": "A0A8V0ZRU2", "uniprot_id": "A0A8V0ZRU2_CHICK", "mass": { "chemical_mass": 52834.0, "monoisotopic_mass": 52834.0 }, "refseq": { "ac": "XP_001233793", "name": "F-box/WD repeat-containing protein 4 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233793" }, "gene_names": [ { "name": "POLL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU2" } ] }, { "name": "POLL", "type": "synonym", "evidence": [ { "id": "XP_001233793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233793" } ] } ], "protein_names": [ { "name": "F-box and WD repeat domain containing 4", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU2/entry#names_and_taxonomy" } ] }, { "name": "F-box/WD repeat-containing protein 4 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_001233793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233793" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_001233793.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001233793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233793" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "POLL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU2", "locus": { "chromosome": "6", "start_pos": 23608681, "end_pos": 23591041, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019104", "url": "https://www.ensembl.org/id/ENSGALG00010019104" } ] } } ], "crossref": [ { "id": "A0A8V0ZRU2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRU2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20090", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20090", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423853", "url": "https://www.ncbi.nlm.nih.gov/gene/423853", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LTHFDMV", "url": "https://omabrowser.org/oma/group/LTHFDMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR14381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14381:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14381:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001233793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001233793", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNQFPNDGVPPRPPPPPPPPEGGSDRQRLLPHVTGERLPPSMAWPPPGSSSSGSRGGGAGAAAPWGGRAAPDPPRRRGDPGPPPPPPSSSSPPSSPLWALPEELLLLICSYLDVQALGRLGQVCRRLRFLSSRDLLWKRIARGCLNSGFTQLGTDLAPGIPVKERVKVSQNWRHGRCRRETVLKWKCNLMPWMELDGQYLYLSQAENIQAYQLCPDGTGLQRHPQAIFSGHQEDVCRFVLVNSHIVSGGGDGNIVLHKIHGSYSVKFSAHEQEVNCVDFQGGFIVSGSRDRTAKVWSLSAGRVGQCLHTVQTEDRVWSIAISPLLSSFVTGTACCGHTSPLRIWDFESGQLLTCLGTDFHHGAGVLDVFYETPSLLLSCGYDTYIRYWDIRTSTRKCVREWEEPHDSALYCIRTDGNHMIASGSSYYGVVRLWDKRQTQCLQSFHLSSPISSPVYCLRFSTTHLYAALASALHVLDFTAS", "length": 480, "header": "tr|A0A8V0ZRU2-1|A0A8V0ZRU2_CHICK Isoform 1 of F-box and WD repeat domain containing 4 OS=Gallus gallus OX=9031 GN=POLL PE=4 SV=1 CANONICAL=A0A8V0ZRU2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU2/entry#A0A8V0ZRU2-1", "sequence": { "sequence": "MNQFPNDGVPPRPPPPPPPPEGGSDRQRLLPHVTGERLPPSMAWPPPGSSSSGSRGGGAGAAAPWGGRAAPDPPRRRGDPGPPPPPPSSSSPPSSPLWALPEELLLLICSYLDVQALGRLGQVCRRLRFLSSRDLLWKRIARGCLNSGFTQLGTDLAPGIPVKERVKVSQNWRHGRCRRETVLKWKCNLMPWMELDGQYLYLSQAENIQAYQLCPDGTGLQRHPQAIFSGHQEDVCRFVLVNSHIVSGGGDGNIVLHKIHGSYSVKFSAHEQEVNCVDFQGGFIVSGSRDRTAKVWSLSAGRVGQCLHTVQTEDRVWSIAISPLLSSFVTGTACCGHTSPLRIWDFESGQLLTCLGTDFHHGAGVLDVFYETPSLLLSCGYDTYIRYWDIRTSTRKCVREWEEPHDSALYCIRTDGNHMIASGSSYYGVVRLWDKRQTQCLQSFHLSSPISSPVYCLRFSTTHLYAALASALHVLDFTAS", "length": 480, "header": "tr|A0A8V0ZRU2-1|A0A8V0ZRU2_CHICK Isoform 1 of F-box and WD repeat domain containing 4 OS=Gallus gallus OX=9031 GN=POLL PE=4 SV=1 CANONICAL=A0A8V0ZRU2-1" }, "locus": { "chromosome": "6", "start_pos": 23587134, "end_pos": 23528573, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010056504.1", "url": "https://www.ensembl.org/id/ENSGALT00010056504.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010034247.1", "url": "https://www.ensembl.org/id/ENSGALP00010034247.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-GGA-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M9M3-1", "protein_name": "F-box/WD repeat-containing protein 4", "gene_name": "FBXW4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNARCVSGTHSGRPGAWEGGALRPPPALRSRSTASGVRGGPRLRPAPPHVTRSGMVSPPPGAAARAWLRVGPAPRPLMGSQGGVGPPGNGGPGEGESGETRKLQEEGRAARGKRRKGKGKAGAGQGGKGNGAEGKPEPPQAKEETGMGAEAGPSAGLGKARERGGSVEEGARRLVRGDEGSAGARKEAKGRGEGKKEEWRVRTGRRESARPARAQGRGGQAWGRLAGTRAAMATAAEEEAAAAREPACRPAAGPALLRLPEELLLLIFSYLDMQALGRLAQVCRWLRRFTSCDLLWRRIARASLNSGFTRLGTDLMASVPVKERVKISQNWRLGRCREGILLKWRCSQMPWMQLEGDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDVCHFVLANSHIISAGGDGKIGIHKIHSTFTVKYSAHVQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRASARKCVMEWEEPHDSTLYCLQTDGNHLLATGSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRFTTRHLYAALSYNLRVLDFQNP", "length": 640 }, "evidence": [ { "id": "A0A8V0ZRU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRU2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A2V7-1", "protein_name": "F-box/WD repeat-containing protein 4", "gene_name": "Fbxw4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTCFNQMFLVLQKMGMSAPRLGFAPRKTGVRGGSRLGPAPPHVTRSVVMSPPLEEAVASSAPLCVEPARRPLMSSQGRSGPPGNRGPREGEGGEARKLQEARVARGKRGKGKGKASTGHGGRGSGAEGKPGLQPARKAAGPAAEAGRGQEGEGGEEEGPRRSGRQDEGSAEPGKEECRVGAGRREDHSLERAQEQERQACGGIPETQTAMAAAAEDGAAAVEPATRPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRPIARASLNSGFTRLGTDLMTSIPVKERVKLSQNWRLGRCRDRILLKWRYSQMPWMQLEDSSLYLSQANFILAYQFRPDGASLNRRPFRVFAGHDEDVCHFVLANSHIISAGGDGKIGVHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGQLGQCLHTIQTEDRVWSIAISPVLSSFVTGTACCGHFSPLRIWDLTSGQLITHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSARKCVMEWEEPHDSTFYCLQTDGNHLLATGSSYYGLVRLWDRRQRACLHAFPLTSTPLSSPVYCLRFTTRHLYAALSYNLHVLDFENP", "length": 617 }, "evidence": [ { "id": "A0A8V0ZRU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRU2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P57775-1", "protein_name": "F-box/WD repeat-containing protein 4", "gene_name": "FBXW4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAGEEEEEEEAARESAARPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIARASLNSGFTRLGTDLMTSVPVKERVKVSQNWRLGRCREGILLKWRCSQMPWMQLEDDSLYISQANFILAYQFRPDGASLNRRPLGVFAGHDEDVCHFVLANSHIVSAGGDGKIGIHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLMTHLGSDFPPGAGVLDVMYESPFTLLSCGYDTYVRYWDLRTSVRKCVMEWEEPHDSTLYCLQTDGNHLLATGSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRLTTKHLYAALSYNLHVLDFQNP", "length": 412 }, "evidence": [ { "id": "A0A8V0ZRU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRU2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JMJ2-1", "protein_name": "F-box/WD repeat-containing protein 4", "gene_name": "Fbxw4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEDAAEDAAAAAVEPATRPAAGPALWRLPEELLLLICSYLDTRALGRLAQVCRWLRRFTSCDLLWRPIARASLNTGFTRLGTDLMAGIPVKERVKLSQNWRLGRCRDRILLKWRYSQMPWMQLQDASLYLSQANFILAYQFRPDGASLNRRPFRVFSGHDEDVCHFVLANSHIVSAGGDGKIGVHKIHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPLLSSFVTGTACCGHFSPLRIWDLNSGQLITHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSTRKCVMEWEEPHDSTFYCLQTDGNHLLATGSSYYGLVRLWDRRQRACLHAFSLTSTPLSSPVYCLRFTTRHLYAALSYNLHVLDFQNP", "length": 410 }, "evidence": [ { "id": "A0A8V0ZRU2", "url": "https://omabrowser.org/oma/group/A0A8V0ZRU2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU2" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 140, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRU4-1", "uniprot_ac": "A0A8V0ZRU4", "uniprot_id": "A0A8V0ZRU4_CHICK", "mass": { "chemical_mass": 33725.0, "monoisotopic_mass": 33725.0 }, "refseq": { "ac": "NP_001280123", "name": "CD276 antigen precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280123" }, "gene_names": [ { "name": "CD276", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4" } ] }, { "name": "B7H3", "type": "synonym", "evidence": [ { "id": "NP_001280123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280123" } ] }, { "name": "CD276", "type": "synonym", "evidence": [ { "id": "NP_001280123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280123" } ] } ], "protein_names": [ { "name": "CD276 antigen", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4/entry#names_and_taxonomy" } ] }, { "name": "B7 homolog 3", "type": "synonym", "evidence": [ { "id": "NP_001280123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280123" }, { "id": "A0A8V0ZRU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4/entry#names_and_taxonomy" } ] }, { "name": "CD276 antigen precursor", "type": "synonym", "evidence": [ { "id": "NP_001280123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280123" } ] }, { "name": "CD276 antigen", "type": "synonym", "evidence": [ { "id": "NP_001280123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280123" } ] }, { "name": "Costimulatory molecule", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267662.64029.1, SRR13267650.20009.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On Jun 3, 2014 this sequence version replaced XP_413702.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001280123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280123" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CD276", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4", "locus": { "chromosome": "10", "start_pos": 2285195, "end_pos": 2276647, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010021650", "url": "https://www.ensembl.org/id/ENSGALG00010021650" } ] } } ], "crossref": [ { "id": "A0A8V0ZRU4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRU4", "database": "AlphaFoldDB", "categories": [] }, { "id": "415315", "url": "https://www.ncbi.nlm.nih.gov/gene/415315", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415315", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415315", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VLWQDSQ", "url": "https://omabrowser.org/oma/group/VLWQDSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRU4", "url": "https://www.orthodb.org/?gene=A0A8V0ZRU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100:SF155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100:SF155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001280123", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001280123", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLALGVLVLGLAGAMEIQVPEEPVVALYGQDATLHCSFSPEANFSLKDLSLIWQLTDTKRLVHSFSDGRDQLTDQGGGYTNRTALFYDQLSQGNVSLLLRRVEIADEGSFTCFVRVRDYNSAAVTLQVAAPYSKPNLNLEPNKDLKPGDPAVVTCQSSYGYPEASILWQDSHGANITENVTTSQIANEEGLFDVYSVLHVLVEPSSTYSCLVRNPLLQQETHASVTITGQHLAFPAVALWVTVGLSICIVVLLAVLAYICQKKIRQSCEEEENAGTEEQDTEGEEQKTALQPLKSTEDKADNEQEID", "length": 308, "header": "tr|A0A8V0ZRU4-1|A0A8V0ZRU4_CHICK Isoform 1 of CD276 antigen OS=Gallus gallus OX=9031 GN=CD276 PE=3 SV=1 CANONICAL=A0A8V0ZRU4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4/entry#A0A8V0ZRU4-1", "sequence": { "sequence": "MLLALGVLVLGLAGAMEIQVPEEPVVALYGQDATLHCSFSPEANFSLKDLSLIWQLTDTKRLVHSFSDGRDQLTDQGGGYTNRTALFYDQLSQGNVSLLLRRVEIADEGSFTCFVRVRDYNSAAVTLQVAAPYSKPNLNLEPNKDLKPGDPAVVTCQSSYGYPEASILWQDSHGANITENVTTSQIANEEGLFDVYSVLHVLVEPSSTYSCLVRNPLLQQETHASVTITGQHLAFPAVALWVTVGLSICIVVLLAVLAYICQKKIRQSCEEEENAGTEEQDTEGEEQKTALQPLKSTEDKADNEQEID", "length": 308, "header": "tr|A0A8V0ZRU4-1|A0A8V0ZRU4_CHICK Isoform 1 of CD276 antigen OS=Gallus gallus OX=9031 GN=CD276 PE=3 SV=1 CANONICAL=A0A8V0ZRU4-1" }, "locus": { "chromosome": "10", "start_pos": 2284135, "end_pos": 2277130, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010052589.1", "url": "https://www.ensembl.org/id/ENSGALT00010052589.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010031495.1", "url": "https://www.ensembl.org/id/ENSGALP00010031495.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415315", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415315", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FXR4-1", "protein_name": "CD276 antigen", "gene_name": "Cd276", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKISAHMAGAAICQGEPSCQLPHRKMLCGWGGPSVGVCMRTALGVLYFCLTGAVEVQVSEDPVVALVDADATLRCSFSLEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPELLEQGNASLRLQRVRVTDEGSYTCFVSIQDFDSAAVSLQVAAPYSKPSMTLEPNKDLRPGNIVTITCSSYQGYPEAEVLWKDGQGLPLTGNVTTSQMANERGLFDVHSVLRVVLGANGIYSCLVRNPVLQQDAHGSVTITGQPMAFPPEALWVTVGLSVCLVVLLVALAFVCWRKIKQSCEEENAGAEDQDGDGEGSKTALRPLKHSENKEGSLPESENPYDPAWRAGVKARGELI", "length": 360 }, "evidence": [ { "id": "A0A8V0ZRU4", "url": "https://omabrowser.org/oma/group/A0A8V0ZRU4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1QM89-1", "protein_name": "CD276 antigen isoform X1", "gene_name": "cd276", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLALLLFSLLVLQSHALDVRVPESPVVVLFGSDALLNCSFSGVSAFNLSDVSVFWQLSDTKRSVHSFWKSQDQLTDQDERFSGRTTLFSDQLMVGNASLRIRKVRVADEGTYSCFVRVQSYGSAAVIMQVAAPFSKPLVSWDSDSSLKPGDAVSLSCVAYGGFPQAQLQWQDGSGHNLTENITVSQLANEEGLFSVRSVLSVHLEPNSTYSCRITNPLLGDESQASVTITGQPLVFPPVALWVTVALAVCLLALLIALAVVCRRKIKESCEEMRAEEEAKELEEARVLEEAKSEATPLKS", "length": 300 }, "evidence": [ { "id": "A0A8V0ZRU4", "url": "https://omabrowser.org/oma/group/A0A8V0ZRU4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7TPB4-1", "protein_name": "CD276 antigen", "gene_name": "Cd276", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRGWGGPSVGVSMGTALGVLCLCLTGAVEVQVSEDPVVALVDTDATLRCSFSPEPGFSLRQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLVQGNASLRLQRVRVTDEGSYTCFVSIQDFDSAAVSLQVAAPYSKPSMTLEPNKDLRPGDMVTITCSSYQGYPEAEVFWKDGQGLPLTGNVTTSQMANERGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLSVCLVILLVALAFVCWRKIKQSCEEENAGAEDQDGDGEGSKTALRPLKHSENKEDDGQEIA", "length": 316 }, "evidence": [ { "id": "A0A8V0ZRU4", "url": "https://omabrowser.org/oma/group/A0A8V0ZRU4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VE98-1", "protein_name": "CD276 antigen", "gene_name": "Cd276", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRGWGGPSVGVCVRTALGVLCLCLTGAVEVQVSEDPVVALVDTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYSNRTALFPDLLVQGNASLRLQRVRVTDEGSYTCFVSIQDFDSAAVSLQVAAPYSKPSMTLEPNKDLRPGNMVTITCSSYQGYPEAEVFWKDGQGVPLTGNVTTSQMANERGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPLTFPPEALWVTVGLSVCLVVLLVALAFVCWRKIKQSCEEENAGAEDQDGDGEGSKTALRPLKPSENKEDDGQEIA", "length": 316 }, "evidence": [ { "id": "A0A8V0ZRU4", "url": "https://omabrowser.org/oma/group/A0A8V0ZRU4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4" } ], "pmid": "" }, { "name": "positive regulation of type II interferon production", "id": "GO:0032729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032729", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4" } ], "pmid": "" }, { "name": "positive regulation of T cell proliferation", "id": "GO:0042102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042102", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0ZRU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU4" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 126, "start_aa": "Gly", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 176, "end_pos": 178 }, { "start_pos": 180, "end_pos": 182 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 82, "end_pos": 84 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0ZRU8-1", "uniprot_ac": "A0A8V0ZRU8", "uniprot_id": "A0A8V0ZRU8_CHICK", "mass": { "chemical_mass": 42479.0, "monoisotopic_mass": 42479.0 }, "refseq": {}, "gene_names": [ { "name": "TTPAL", "type": "recommended", "evidence": [ { "id": "A0A8V0ZRU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU8" } ] } ], "protein_names": [ { "name": "Alpha tocopherol transfer protein like", "type": "synonym", "evidence": [ { "id": "A0A8V0ZRU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0ZRU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTPAL", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU8", "locus": { "chromosome": "20", "start_pos": 5746310, "end_pos": 5755323, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024323", "url": "https://www.ensembl.org/id/ENSGALG00010024323" } ] } } ], "crossref": [ { "id": "A0A8V0ZRU8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0ZRU8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRU8", "url": "https://www.orthodb.org/?gene=A0A8V0ZRU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZRV3", "url": "https://www.orthodb.org/?gene=A0A8V0ZRV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10174", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10174", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10174:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10174:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28528", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28528", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0ZRU8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRV3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZRV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRTQWQCPSCAGLQCRFLSRDAAHPKCIRDKGCCHAMSGDSDCTRTSPSAGSPSDPEALPDRPQYVCSLSADLVTKAREELQEKPEWRLRDVQALRDMVCKDYPSLGTCLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRSWPEVFNNLKPSAIKPVLESGFVTVLPRLDPEGRHVVCIRPDRWTPSHYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFVAKKVIGILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHQNIPPVILPEEYGGTAGKLDISAWNELLLASEEDFLHDFSQLVLPCDSSPHDMPVSGDADEKQCDDSLRGMKPQLYYCY", "length": 376, "header": "tr|A0A8V0ZRU8-1|A0A8V0ZRU8_CHICK Isoform 1 of Alpha tocopherol transfer protein like OS=Gallus gallus OX=9031 GN=TTPAL PE=1 SV=1 CANONICAL=A0A8V0ZRU8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU8/entry#A0A8V0ZRU8-1", "sequence": { "sequence": "MPRTQWQCPSCAGLQCRFLSRDAAHPKCIRDKGCCHAMSGDSDCTRTSPSAGSPSDPEALPDRPQYVCSLSADLVTKAREELQEKPEWRLRDVQALRDMVCKDYPSLGTCLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRSWPEVFNNLKPSAIKPVLESGFVTVLPRLDPEGRHVVCIRPDRWTPSHYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFVAKKVIGILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHQNIPPVILPEEYGGTAGKLDISAWNELLLASEEDFLHDFSQLVLPCDSSPHDMPVSGDADEKQCDDSLRGMKPQLYYCY", "length": 376, "header": "tr|A0A8V0ZRU8-1|A0A8V0ZRU8_CHICK Isoform 1 of Alpha tocopherol transfer protein like OS=Gallus gallus OX=9031 GN=TTPAL PE=1 SV=1 CANONICAL=A0A8V0ZRU8-1" }, "locus": { "chromosome": "20", "start_pos": 5753346, "end_pos": 5749750, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059297.1", "url": "https://www.ensembl.org/id/ENSGALT00010059297.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010036191.1", "url": "https://www.ensembl.org/id/ENSGALP00010036191.1" } ] } }, { "isoform_ac": "A0A8V0ZRV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU8/entry#A0A8V0ZRV3-1", "sequence": { "sequence": "MRQELSAEQPLSAGEVCMHTVRCFQPPAATGCCHAMSGDSDCTRTSPSAGSPSDPEALPDRPQYVCSLSADLVTKAREELQEKPEWRLRDVQALRDMVCKDYPSLGTCLDDAFLLRFLRARKFDYDRALQLLVNYHSCRRSWPEVFNNLKPSAIKPVLESGFVTVLPRLDPEGRHVVCIRPDRWTPSHYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFVAKKVIGILQDGFPIRIKAVNIINEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHQNIPPVILPEEYGGTAGKLDISAWNELLLASEEDFLHDFSQLVLPCDSSPHDMPVSGDADEKQCDDSLRGMKPQLYYCY", "length": 374, "header": "tr|A0A8V0ZRV3-1|A0A8V0ZRV3_CHICK Computationally mapped isoform of Alpha tocopherol transfer protein like OS=Gallus gallus OX=9031 GN=TTPAL PE=1 SV=1 CANONICAL=A0A8V0ZRU8-1" }, "locus": { "chromosome": "20", "start_pos": 5755208, "end_pos": 5749750, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010059304.1", 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"MSRDVLDTALKLPHVDCIEEDAYVFAQSIPWNLGRIVPPLPGTDTYSPPNEGDKVQIYLLDTSVQSTHREIAGRVLITDFQNVPEEDSSRFHRQASKCDSHGTHMAGVLSGRDAGVARGAHIHSLRVLNCQGKGTVSGVLIGLEFVRASLEAQPSPPLVVLLPFAGAHSRVLNAGCRRMVQMGAVVVVAAGNYKDDACLYSPASEPEVITVGATNREDRPASISTLGTNFGRCVDLFAPGDDIIGASSDCSTCFTARSGTSQAAAHVAGVAAMLLSAEPHLSAAELRQRLLHLATKNVISTAWFPEEQRLQTPSSIVGLPAQLGPDKELLCRSVWSARSGPTRHATAVARCAGTEELLGCSSFSHSGWRLGEHMEDKEGQKQCVAHNAFGGRGVYAIARCCTWPHTQCRLNTSSQGDDGAGCSPQDHVLTGCSFHSPVAALGDGGRPVLGPGSRPGGCTTRPEGTAHASCCPAAMLECRVKEHAPQGSAEKVTVSCDAGWTLTDCSAHSQGPGTLGSYAVADTCVAASTPGSHAPGAVAICCRSQQ", "length": 546, "header": "tr|A0A8V0ZRU9-1|A0A8V0ZRU9_CHICK Isoform 1 of Proprotein convertase subtilisin/kexin type 9 OS=Gallus gallus OX=9031 GN=PCSK9 PE=3 SV=1 CANONICAL=A0A8V0ZRU9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0ZRU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRU9/entry#A0A8V0ZRU9-1", "sequence": { "sequence": 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"id": "ENSGALP00010033553.1", "url": "https://www.ensembl.org/id/ENSGALP00010033553.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 529, "start_aa": "Thr", "end_pos": 529, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr529", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-381426", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-381426", "resource": "Reactome", "description": "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth 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Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_414809.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414809", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414809" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NT5M", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9", "locus": { "chromosome": "14", "start_pos": 4769278, "end_pos": 4762694, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017495", "url": "https://www.ensembl.org/id/ENSGALG00010017495" } ] } } ], "crossref": [ { "id": "A0A8V0Z2T9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z2T9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02587", "url": 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{ "id": "A0A8V0Z2T9", "url": "https://www.orthodb.org/?gene=A0A8V0Z2T9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16504", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16504", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16504:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16504:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06941", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06941", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-73621", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73621", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_414809", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414809", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MILLSSILHLRPRHCGPLAGLGRGSCPTAGSRRALRVLVDMDGVLADFEGGFLKKFRARYPDKPYIALEDRRGFWVSEQYGRLAAELSEKAISIWESKNFFIELDPLPGAVEAVKQMSNLADTDVFICTSPIKKYRYCPYEKYAWVEKHFGPEFLEQIVLTRDKTVVSADLLIDDRPDITGAEVNPSWEHVLFTACHNKHLQLEPPRRRLQSWSDDWRAILDSKRLPLGHTA", "length": 232, "header": "tr|A0A8V0Z2T9-1|A0A8V0Z2T9_CHICK Isoform 1 of 5',3'-nucleotidase, mitochondrial OS=Gallus gallus OX=9031 GN=NT5M PE=3 SV=1 CANONICAL=A0A8V0Z2T9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9/entry#A0A8V0Z2T9-1", "sequence": { "sequence": "MILLSSILHLRPRHCGPLAGLGRGSCPTAGSRRALRVLVDMDGVLADFEGGFLKKFRARYPDKPYIALEDRRGFWVSEQYGRLAAELSEKAISIWESKNFFIELDPLPGAVEAVKQMSNLADTDVFICTSPIKKYRYCPYEKYAWVEKHFGPEFLEQIVLTRDKTVVSADLLIDDRPDITGAEVNPSWEHVLFTACHNKHLQLEPPRRRLQSWSDDWRAILDSKRLPLGHTA", "length": 232, "header": "tr|A0A8V0Z2T9-1|A0A8V0Z2T9_CHICK Isoform 1 of 5',3'-nucleotidase, mitochondrial OS=Gallus gallus OX=9031 GN=NT5M PE=3 SV=1 CANONICAL=A0A8V0Z2T9-1" }, "locus": { "chromosome": "14", "start_pos": 4766791, "end_pos": 4763173, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042272.1", "url": "https://www.ensembl.org/id/ENSGALT00010042272.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024775.1", "url": "https://www.ensembl.org/id/ENSGALP00010024775.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 28, "start_aa": "Thr", "end_pos": 28, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr28", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:416505", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416505", "resource": "KEGG Pathway" }, { "id": "R-GGA-73621", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-73621", "resource": "Reactome", "description": "Pyrimidine catabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A5J2-1", "protein_name": "5',3'-nucleotidase, mitochondrial", "gene_name": "Nt5m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLRGCCARPRGAPLRAERSRASSRALRVLVDMDGVLADFEGGFLRKFRARFPDLPFVALEDRRGFWVSEQYGRLQPGLSEKAISIWESKDFFFELEPLPGAVEAVKHMASLQNTDVFICTSPIKMFKYCPYEKYAWVEKHFGPDFLEQIVLTRDKTVVSADLLIDDRPDITGAESHPSWEHILFTSCHNYHLQLQPPRRRLHSWADDWKAILDSKRPR", "length": 220 }, "evidence": [ { "id": "A0A8V0Z2T9", "url": "https://omabrowser.org/oma/group/A0A8V0Z2T9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SB15-1", "protein_name": "5',3'-nucleotidase, mitochondrial", "gene_name": "NT5M", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIRLRGWCARRPRGATRPAGPAGRRWASGGPGGRALRVLVDMDGVLADFEGGFLRKFRARFPDQPFIALEDRRGFWVSEQYGRLQPGLSEKAISIWESENFFFDLEPLPGAVEAVKQMANLESTEVFICTSPIKMYKYCPFEKYAWVEKHLGSDFLEQIVLTRDKTVVSADLLIDDRLDITGAEPNPSWEHVLFTACHNRHMQLQPPSRRLHSWADDWRAILDSKRPR", "length": 228 }, "evidence": [ { "id": "A0A8V0Z2T9", "url": "https://omabrowser.org/oma/group/A0A8V0Z2T9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8VCE6-1", "protein_name": "5'(3')-deoxyribonucleotidase, mitochondrial", "gene_name": "Nt5m", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLRGCCARPRGAPLRAERSRASSRALRVLVDMDGVLADFEGGFLRKFRARFPDLPFVALEDRRGFWVSEQYGRLQPGLSEKAISIWESKDFFFELEPLPGAVEAVKQMANLQNTDVFICTSPIKMFKYCPYEKYAWVEKHFGPDFLEQIVLTRDKTVISADLLIDDRPDITGAEPHPSWEHILFTSCHNYHLQLQPPRRRLHSWADDWKAILDSKRLR", "length": 220 }, "evidence": [ { "id": "A0A8V0Z2T9", "url": "https://omabrowser.org/oma/group/A0A8V0Z2T9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "dUMP catabolic process", "id": "GO:0046079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046079", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "pmid": "" }, { "name": "pyrimidine deoxyribonucleotide catabolic process", "id": "GO:0009223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009223", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "pmid": "" }, { "name": "GMP catabolic process", "id": "GO:0046038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046038", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "pmid": "" }, { "name": "UMP catabolic process", "id": "GO:0046050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046050", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "pmid": "" }, { "name": "dTMP catabolic process", "id": "GO:0046074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046074", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "pmid": "" }, { "name": "dGMP catabolic process", "id": "GO:0046055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "pmid": "" }, { "name": "TMP catabolic process", "id": "GO:0046045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "3'-nucleotidase activity", "id": "GO:0008254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "pmid": "" }, { "name": "5'-nucleotidase activity", "id": "GO:0008253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008253", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2T9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 28 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z2W4-1", "uniprot_ac": "A0A8V0Z2W4", "uniprot_id": "A0A8V0Z2W4_CHICK", "mass": { "chemical_mass": 43465.0, "monoisotopic_mass": 43465.0 }, "refseq": {}, "gene_names": [ { "name": "LOC427665", "type": "recommended", "evidence": [ { "id": "A0A8V0Z2W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2W4" } ] } ], "protein_names": [ { "name": "G protein-coupled receptor 33", "type": "synonym", "evidence": [ { "id": "A0A8V0Z2W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2W4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2W4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC427665", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2W4", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z2W4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z2W4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427665", "url": "https://www.ncbi.nlm.nih.gov/gene/427665", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427665", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427665", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LWRMRHK", "url": "https://omabrowser.org/oma/group/LWRMRHK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2V9", "url": "https://www.orthodb.org/?gene=A0A8V0Z2V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z2W4", "url": "https://www.orthodb.org/?gene=A0A8V0Z2W4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24225", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24225", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24225:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24225:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z2V9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2W4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z2W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2W4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAWDAPSEESGEQPESHWRREDPSLLAMESVSSSPSPFPDSSPSVPSGNATAHDHYSGLQKSLHVLSMVVYSIACVLGVTGNGLVIWIAGFKMKKTVNSVWFLNLAIADFIFTFFLPLSIAYTALDFHWPFGKLLCKLNSTIAFLNMFASVFLLMVISVDRCVSVAFPVWSHNRRSPELAARVALGTWGMAVLLSSPYLIFRDTAVSSRNITSCYNNFALSDDYTAEETRRLWRMRHKAMIITRFLCGFLIPFTVILICYSIVAVKLKRRQLASSAKPYRIIIAVTVSFFLCYFPYHVFSLLEISQNSSSHEMKMALYIGIPLVSSLAFFNSCINPILYVFVGPDFKEKFCQSILSTFEGAFTEESMLGSLSSRRKSRSASEAEVPRL", "length": 388, "header": "tr|A0A8V0Z2W4-1|A0A8V0Z2W4_CHICK Isoform 1 of G protein-coupled receptor 33 OS=Gallus gallus OX=9031 GN=LOC427665 PE=3 SV=1 CANONICAL=A0A8V0Z2W4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2V9-1", "url": 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"id": "A0A8V0Z8T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9G5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9I9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9I9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA95", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMGVGLGGASLCSPILVPSALFRGARVPPQPRCPHRWVGRGCRRVARQPVASAERGQSPTLLGAGTAVGWGSWNGCGRGVPRGSPALDKDVSVWCPAGQLAAGMAQPSAPPPYDDKNPLYPPSAYPQPSHYGGGYPQPGGYPAPAGYVAPGGYGTPGGYPQPGMAMPTMPVRFGDTYGGDGMGHSSPIQSADWDDRKVRHSFIRKVYAIISVQLLVTVGIIAMFTFVSPVRSFVQRNIAVYYSSYAVFLVTYLVLVCCQGPRRRFPWNLILLSIFTLAMSFMTGTIASMYQTKAVLIAMLITAIVAIIVTIFCFQTKVDFTSCTGLFCVLGIVVMVTGIVTVIVLSFKYVPWLHMLYAAIGAIAFTLFLAYDTQLVLGNRKNTLSPEEYIYGALTIYTDIVYIFTFLLQIVGRD", "length": 414, "header": "tr|A0A8V0Z2X0-1|A0A8V0Z2X0_CHICK Isoform 1 of Transmembrane BAX inhibitor motif containing 1 OS=Gallus gallus OX=9031 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A8V0Z2X0-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0/entry#A0A8V0Z2X0-1", "sequence": { "sequence": "MMGVGLGGASLCSPILVPSALFRGARVPPQPRCPHRWVGRGCRRVARQPVASAERGQSPTLLGAGTAVGWGSWNGCGRGVPRGSPALDKDVSVWCPAGQLAAGMAQPSAPPPYDDKNPLYPPSAYPQPSHYGGGYPQPGGYPAPAGYVAPGGYGTPGGYPQPGMAMPTMPVRFGDTYGGDGMGHSSPIQSADWDDRKVRHSFIRKVYAIISVQLLVTVGIIAMFTFVSPVRSFVQRNIAVYYSSYAVFLVTYLVLVCCQGPRRRFPWNLILLSIFTLAMSFMTGTIASMYQTKAVLIAMLITAIVAIIVTIFCFQTKVDFTSCTGLFCVLGIVVMVTGIVTVIVLSFKYVPWLHMLYAAIGAIAFTLFLAYDTQLVLGNRKNTLSPEEYIYGALTIYTDIVYIFTFLLQIVGRD", "length": 414, "header": "tr|A0A8V0Z2X0-1|A0A8V0Z2X0_CHICK Isoform 1 of Transmembrane BAX inhibitor motif containing 1 OS=Gallus gallus OX=9031 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A8V0Z2X0-1" }, "locus": { "chromosome": "7", "start_pos": 22187450, "end_pos": 22183129, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046300.1", "url": "https://www.ensembl.org/id/ENSGALT00010046300.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027573.1", "url": "https://www.ensembl.org/id/ENSGALP00010027573.1" } ] } }, { "isoform_ac": "A0A8V0Z2Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0/entry#A0A8V0Z2Z7-1", "sequence": { "sequence": "MCGPPSKAGDPCWCPAGQLAAGMAQPSAPPPYDDKNPLYPPSAYPQPSHYGGGYPQPGGYPAPAGYVAPGGYGTPGGYPQPGMAMPTMPVRFGDTYGGDGMGHSSPIQSADWDDRKVRHSFIRKVYAIISVQLLVTVGIIAMFTFVSPVRSFVQRNIAVYYSSYAVFLVTYLVLVCCQGPRRRFPWNLILLSIFTLAMSFMTGTIASMYQTKAVLIAMLITAIVAIIVTIFCFQTKVDFTSCTGLFCVLGIVVMVTGIVTVIVLSFKYVPWLHMLYAAIGAIAFTLFLAYDTQLVLGNRKNTLSPEEYIYGALTIYTDIVYIFTFLLQIVGRD", "length": 333, "header": "tr|A0A8V0Z2Z7-1|A0A8V0Z2Z7_CHICK Computationally mapped isoform of Transmembrane BAX inhibitor motif containing 1 OS=Gallus gallus OX=9031 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A8V0Z2X0-1" }, "locus": { "chromosome": "7", "start_pos": 22187450, "end_pos": 22165451, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046348.1", "url": "https://www.ensembl.org/id/ENSGALT00010046348.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027603.1", "url": "https://www.ensembl.org/id/ENSGALP00010027603.1" } ] } }, { "isoform_ac": "A0A8V0Z8T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0/entry#A0A8V0Z8T0-1", "sequence": { "sequence": "MTSAPGCPAGQLAAGMAQPSAPPPYDDKNPLYPPSAYPQPSHYGGGYPQPGGYPAPAGYVAPGGYGTPGGYPQPGMAMPTMPVRFGDTYGGDGMGHSSPIQSADWDDRKVRHSFIRKVYAIISVQLLVTVGIIAMFTFVSPVRSFVQRNIAVYYSSYAVFLVTYLVLVCCQGPRRRFPWNLILLSIFTLAMSFMTGTIASMYQTKAVLIAMLITAIVAIIVTIFCFQTKVDFTSCTGLFCVLGIVVMVTGIVTVIVLSFKYVPWLHMLYAAIGAIAFTLFLAYDTQLVLGNRKNTLSPEEYIYGALTIYTDIVYIFTFLLQIVGRD", "length": 326, "header": "tr|A0A8V0Z8T0-1|A0A8V0Z2X0_CHICK Computationally mapped isoform of Transmembrane BAX inhibitor motif containing 1 OS=Gallus gallus OX=9031 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A8V0Z2X0-1" }, "locus": { "chromosome": "7", "start_pos": 22187450, "end_pos": 22182208, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046308.1", "url": "https://www.ensembl.org/id/ENSGALT00010046308.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027580.1", "url": "https://www.ensembl.org/id/ENSGALP00010027580.1" } ] } }, { "isoform_ac": "A0A8V0Z8T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0/entry#A0A8V0Z8T9-1", "sequence": { "sequence": "MSPAAPTVLPLGMLMSSSRCPAGQLAAGMAQPSAPPPYDDKNPLYPPSAYPQPSHYGGGYPQPGGYPAPAGYVAPGGYGTPGGYPQPGMAMPTMPVRFGDTYGGDGMGHSSPIQSADWDDRKVRHSFIRKVYAIISVQLLVTVGIIAMFTFVSPVRSFVQRNIAVYYSSYAVFLVTYLVLVCCQGPRRRFPWNLILLSIFTLAMSFMTGTIASMYQTKAVLIAMLITAIVAIIVTIFCFQTKVDFTSCTGLFCVLGIVVMVTGIVTVIVLSFKYVPWLHMLYAAIGAIAFTLFLAYDTQLVLGNRKNTLSPEEYIYGALTIYTDIVYIFTFLLQIVGRD", "length": 339, "header": "tr|A0A8V0Z8T9-1|A0A8V0Z2X0_CHICK Computationally mapped isoform of Transmembrane BAX inhibitor motif containing 1 OS=Gallus gallus OX=9031 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A8V0Z2X0-1" }, "locus": { "chromosome": "7", "start_pos": 22187450, "end_pos": 22175234, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046323.1", "url": "https://www.ensembl.org/id/ENSGALT00010046323.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027590.1", "url": "https://www.ensembl.org/id/ENSGALP00010027590.1" } ] } }, { "isoform_ac": "A0A8V0Z9G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0/entry#A0A8V0Z9G5-1", "sequence": { "sequence": "MLLEERRRCPAGQLAAGMAQPSAPPPYDDKNPLYPPSAYPQPSHYGGGYPQPGGYPAPAGYVAPGGYGTPGGYPQPGMAMPTMPVRFGDTYGGDGMGHSSPIQSADWDDRKVRHSFIRKVYAIISVQLLVTVGIIAMFTFVSPVRSFVQRNIAVYYSSYAVFLVTYLVLVCCQGPRRRFPWNLILLSIFTLAMSFMTGTIASMYQTKAVLIAMLITAIVAIIVTIFCFQTKVDFTSCTGLFCVLGIVVMVTGIVTVIVLSFKYVPWLHMLYAAIGAIAFTLFLAYDTQLVLGNRKNTLSPEEYIYGALTIYTDIVYIFTFLLQIVGRD", "length": 328, "header": "tr|A0A8V0Z9G5-1|A0A8V0Z2X0_CHICK Computationally mapped isoform of Transmembrane BAX inhibitor motif containing 1 OS=Gallus gallus OX=9031 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A8V0Z2X0-1" }, "locus": { "chromosome": "7", "start_pos": 22187450, "end_pos": 22181622, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046314.1", "url": "https://www.ensembl.org/id/ENSGALT00010046314.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027582.1", "url": "https://www.ensembl.org/id/ENSGALP00010027582.1" } ] } }, { "isoform_ac": "A0A8V0Z9I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0/entry#A0A8V0Z9I9-1", "sequence": { "sequence": "MANLWHSSPSTVAHSSTHSSCRGRRRAAWAGGGQHTLHPIGSPSSPGLTLKPATAPHCRSDSTLPGSRCPAGQLAAGMAQPSAPPPYDDKNPLYPPSAYPQPSHYGGGYPQPGGYPAPAGYVAPGGYGTPGGYPQPGMAMPTMPVRFGDTYGGDGMGHSSPIQSADWDDRKVRHSFIRKVYAIISVQLLVTVGIIAMFTFVSPVRSFVQRNIAVYYSSYAVFLVTYLVLVCCQGPRRRFPWNLILLSIFTLAMSFMTGTIASMYQTKAVLIAMLITAIVAIIVTIFCFQTKVDFTSCTGLFCVLGIVVMVTGIVTVIVLSFKYVPWLHMLYAAIGAIAFTLFLAYDTQLVLGNRKNTLSPEEYIYGALTIYTDIVYIFTFLLQIVGRD", "length": 388, "header": "tr|A0A8V0Z9I9-1|A0A8V0Z2X0_CHICK Computationally mapped isoform of Transmembrane BAX inhibitor motif containing 1 OS=Gallus gallus OX=9031 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A8V0Z2X0-1" }, "locus": { "chromosome": "7", "start_pos": 22187450, "end_pos": 22174330, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046341.1", "url": "https://www.ensembl.org/id/ENSGALT00010046341.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027602.1", "url": "https://www.ensembl.org/id/ENSGALP00010027602.1" } ] } }, { "isoform_ac": "A0A8V0ZA95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0/entry#A0A8V0ZA95-1", "sequence": { "sequence": "MRVGGSLPAPGVWGRSLATAPGSAIVFLALALLPFSSSSASCSGGVGPALALLPARLLAAVGGSARGAQRGVPVPPPLQLCPSQVPALRWCPAGQLAAGMAQPSAPPPYDDKNPLYPPSAYPQPSHYGGGYPQPGGYPAPAGYVAPGGYGTPGGYPQPGMAMPTMPVRFGDTYGGDGMGHSSPIQSADWDDRKVRHSFIRKVYAIISVQLLVTVGIIAMFTFVSPVRSFVQRNIAVYYSSYAVFLVTYLVLVCCQGPRRRFPWNLILLSIFTLAMSFMTGTIASMYQTKAVLIAMLITAIVAIIVTIFCFQTKVDFTSCTGLFCVLGIVVMVTGIVTVIVLSFKYVPWLHMLYAAIGAIAFTLFLAYDTQLVLGNRKNTLSPEEYIYGALTIYTDIVYIFTFLLQIVGRD", "length": 410, "header": "tr|A0A8V0ZA95-1|A0A8V0Z2X0_CHICK Computationally mapped isoform of Transmembrane BAX inhibitor motif containing 1 OS=Gallus gallus OX=9031 GN=TMBIM1 PE=1 SV=1 CANONICAL=A0A8V0Z2X0-1" }, "locus": { "chromosome": "7", "start_pos": 22187450, "end_pos": 22184657, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046283.1", "url": "https://www.ensembl.org/id/ENSGALT00010046283.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027566.1", "url": "https://www.ensembl.org/id/ENSGALP00010027566.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 155, "start_aa": "Thr", "end_pos": 155, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr155", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" }, { "name": "death receptor binding", "id": "GO:0005123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" }, { "name": "negative regulation of protein localization to plasma membrane", "id": "GO:1903077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903077", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" }, { "name": "negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "id": "GO:1902042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902042", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" }, { "name": "negative regulation of Fas signaling pathway", "id": "GO:1902045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z2X0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2X0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": 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"MAAAETKIIYHLDEQETPYLVKLPIPAERVTLGDFKGLLNRPNYKFYFKSMDDDFGVVKEEISDDNAKLPCFNGRVVSWLVSAEGSHSDAGSVCADNQTELPPSMERTGGIGDSRPPSFHPNTGGSRENLDNETETDSVVSSQRERPRRKDGPEHAPRVNGTVKGERRRDLGGYESSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKAPRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFSLPRSKWIADSPLMLVPSSFAPQRIWAGPDSPCSDPGEPIRPIDPAAWVSHTAAMTGTYPAYGMSPSMSTITSTSSSITSSIPETERLDDFHLSIHSDMATIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHHVEGFTDRRESRKYASNLLKAGYIRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQYPPPHPYNPHPGFPDPSYSYGGGSAGSQHSEGSRSSGSNRSGSERRKEREKTGESKSGGSGSESDHTTRSSMRRERAASERSVPASQHSQRSQHSLAHSIRSHHSQQSYGPPGLPPLFSPPMLLMPPPPSAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM", "length": 744, "header": "tr|A0A8V0Z2Y5-1|A0A8V0Z2Y5_CHICK Isoform 1 of Dishevelled segment polarity protein 2 OS=Gallus gallus OX=9031 GN=DVL2 PE=1 SV=1 CANONICAL=A0A8V0Z2Y5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z2Y5-1", "url": 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This record is derived from a genomic sequence (NC_052552.1) annotated using gene prediction method: Gnomon, supported by EST evidence. 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Transcript", "id": "ENSGALT00010046362.1", "url": "https://www.ensembl.org/id/ENSGALT00010046362.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027608.1", "url": "https://www.ensembl.org/id/ENSGALP00010027608.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 526, "start_aa": "Thr", "end_pos": 526, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr526", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:100859891", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100859891", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9S3P0-1", "protein_name": "G protein-coupled receptor 153", "gene_name": "GPR153", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSDERRLPGSAVGWLACGGLSLLANAWGILSVGAKQKKWKPLEFLLCTLAATHMLNVAVPIATYAVVQLRRQRPDYEWNEGLCKVFVSTFYTLTLATCFSVTSLSYHRMWMVRWPVNYRLSNAKKQAVHTVMGIWMVSFILSALPAVGWHDTSERFYTHGCRFIVAEIGLGFGVCFLLLVGGSVAMGAVCTAIALFQTLAVQVGRRADRRAFTVPTIVVEDAQGKRRSSIDGSEPARTSLQITGLVATIVVIYDCLMGFPVLVVSFSSLRADASAPWMALCVLWCSVTQALLLPVFLWACDRYRADFKAVWEKCMALMANDEESDDDTSLEGGVPPDLVLERSLDYNYGGDFVALDRMAKYELSALEEGGLPQFYPLRPLQEDKMQYLQVPPTRRFSHDDADVWAAVPLPTFLPHWGSGEDLAALVMPSGPDRRRGSLLAFAEDAPPFRPRRRSAESLLSLRPLALDDSPRRAPGSPPSSPRRRPGPGVRCASASLLPDAFALTAFEREPQALRRQPGPPGSFPACAPAADRTQPGGDVAPPGGGAQRSPGPLPDAHMHSGTLRTGLSASWGEPDGLRAAGAGSTSSFLSSPSESSGYVTLHSDSLGSAS", "length": 610 }, "evidence": [ { "id": "A0A8V0Z303", "url": "https://omabrowser.org/oma/group/A0A8V0Z303/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4ABT6-1", "protein_name": "G protein-coupled receptor 153", "gene_name": "Gpr153", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDERRLPGSAVGWLACGGLSLLANAWGILSVGAKQKKWKPLEFLLCTLAATHMLNVAVPIATYAVVQLRRQRPDYEWNEGLCKVFVSTFYTLTLATCFSVTSISYHRMWMVRWPVNYRLSNAKKQAVHTVMGIWMVSFILSALPAVGWHDTSERFYTHGCRFIVAEIGLGFGVCFLLLVGGSVAMGVVCTAIALFQTLATQVGHRADRRAFTVPTIVVEDAQGKRRSSIDGSEPARTSLQITGLVATIVVIYDCLMGFPVLVVSFSSLRADASAPWMVLCVLWCSVTQALLLPLFLWTCDRYRADLKAVWEKCVALMANDEDSDNETSLEGSISPDLVLERSLDYGGDFVALDRMAKYELSALEGGLPQLYPLRPLQEDRMQYLQGAGRHRCGFPGGQPCFSPAGCSQVPPTRRFSHDDADVWAAIPLPTFLPRWSSGEDLAALAHLMLPAGSDRRRGSLLAFTEDAPPFRPRRRSAESLLSLQPSSLDGGPRRAQDSPPGSPCRRPGPGARSASVSLLPDAFALTAFDREPQPLRRVPAPARPFPAAPDGTETAEIPTPPGGRAQRSQGRRAARAHAGPLQSSLSASWGEPGGLLAAGCGSTSSFLSSPSESSGYVTLHSDSLGSAS", "length": 629 }, "evidence": [ { "id": "A0A8V0Z303", "url": "https://omabrowser.org/oma/group/A0A8V0Z303/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NV75-1", "protein_name": "Probable G protein-coupled receptor 153", "gene_name": "GPR153", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDERRLPGSAVGWLVCGGLSLLANAWGILSVGAKQKKWKPLEFLLCTLAATHMLNVAVPIATYSVVQLRRQRPDFEWNEGLCKVFVSTFYTLTLATCFSVTSLSYHRMWMVCWPVNYRLSNAKKQAVHTVMGIWMVSFILSALPAVGWHDTSERFYTHGCRFIVAEIGLGFGVCFLLLVGGSVAMGVICTAIALFQTLAVQVGRQADRRAFTVPTIVVEDAQGKRRSSIDGSEPAKTSLQTTGLVTTIVFIYDCLMGFPVLVVSFSSLRADASAPWMALCVLWCSVAQALLLPVFLWACDRYRADLKAVREKCMALMANDEESDDETSLEGGISPDLVLERSLDYGYGGDFVALDRMAKYEISALEGGLPQLYPLRPLQEDKMQYLQVPPTRRFSHDDADVWAAVPLPAFLPRWGSGEDLAALAHLVLPAGPERRRASLLAFAEDAPPSRARRRSAESLLSLRPSALDSGPRGARDSPPGSPRRRPGPGPRSASASLLPDAFALTAFECEPQALRRPPGPFPAAPAAPDGADPGEAPTPPSSAQRSPGPRPSAHSHAGSLRPGLSASWGEPGGLRAAGGGGSTSSFLSSPSESSGYATLHSDSLGSAS", "length": 609 }, "evidence": [ { "id": "A0A8V0Z303", "url": "https://omabrowser.org/oma/group/A0A8V0Z303/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K0Z9-1", "protein_name": "Probable G protein-coupled receptor 153", "gene_name": "Gpr153", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDERRLPSSAVGWLACGGLSLLANAWGILSVGAKQKKWKPLEFLLCTLAATHMLNVAVPIATYAVVQLRRQRPDYEWNEGLCKVFVSTFYTLTLATCFSVTSISYHRMWMVRWPVNYRLSNAKKQAVHTVMGIWMVSFILSALPAVGWHDTSERFYTHGCRFIVAEIGLGFGVCFLLLVGGSVAMGMVCTAIALFQTLATQVGHRADRRTFTVPTIVVEDAQGKRRSSIDGSEPARTSLQITGLVATIVVIYDCLMGFPVLVVSFSSLRADASAPWMALCVLWCSVTQALLLPLFLWTCDRYRADLKAVWEKCVALMANDEDSDNETSLEGSISPDMVLERSLDYSYGGDFVALDRMAKYELSALEGGLPQLYPLRPLQEDRMQYLQGAGRHRCGFPGGQPCFSPAGCSQVPPTRRFSHDDADVWAAVPLPTFLPRWSSGEDLAALAHLMLPAGSDRRRGSLLAFAEDAPPFRPRRRSAESLLSLQPSSLDGGPRHAQDSPPGSPRRRPGPGARSASVSLLPDAFALTAFEREPQALRRVPAPAQPFPAARDSAEPAEVPTPPGGRTQRSQGRRAARTHVGPLQSSLSASWGEPGGLHAAGCGSISSFLSSPSESSGYVTLHSDSLGSAS", "length": 631 }, "evidence": [ { "id": "A0A8V0Z303", "url": "https://omabrowser.org/oma/group/A0A8V0Z303/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z303", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z303" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z303", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z303" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z303", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z303" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 297, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 526 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z307-1", "uniprot_ac": "A0A8V0Z307", "uniprot_id": "A0A8V0Z307_CHICK", "mass": { "chemical_mass": 121662.0, "monoisotopic_mass": 121662.0 }, "refseq": {}, "gene_names": [ { "name": "NEMF", "type": "recommended", "evidence": [ { "id": "A0A8V0Z307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z307" } ] } ], "protein_names": [ { "name": "Ribosome quality control complex subunit NEMF", "type": "recommended", "evidence": [ { "id": "A0A8V0Z307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z307/entry#names_and_taxonomy" } ] }, { "name": "Nuclear export mediator factor", "type": "synonym", "evidence": [ { "id": "A0A8V0Z307", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z307/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z307", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z307" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NEMF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z307", "locus": { "chromosome": "5", "start_pos": 57435680, "end_pos": 57456666, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019172", "url": "https://www.ensembl.org/id/ENSGALG00010019172" } ] } } ], "crossref": [ { "id": "A0A8V0Z307", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z307", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR008532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z307", "url": "https://www.orthodb.org/?gene=A0A8V0Z307", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15239:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15239:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9954709", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z307", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z307", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z307-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z307-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSRFSTVDIRALVAELRLSLLGMRVNNVYDVDSKTYLIRLQKPDCKATLLLESGIRIHTTEFEWPKNMMPSGFAMKCRKHLKTRRLVSVRQLGIDRIVDFQFGSNEAAYHLIIELYDRGNIVLTDHEYLILNILRFRTDEADDVRFAVRERYPVDSAKAPTPLPTLERLTEIISNAPKGEQLKRVLNPHLPYGATLIEHCLIEAGFSGYVKIDQHMESKENIEKVLSALEKAEGYMTLTEDFSGKGYIIQKKEKKPSLEPDKPAEDIYTYEEFHPFLFSQHSKCPYLEFDSFNKAADEFYSKLEGQKIDLKALQQEKQALKKLENVRRDHEQRLEALQQAQEVDKIKGELIEMNLEIVSRAIQVVRSALANQIDWTEIGAIVKEAQAQGDPVANAIKELKLQTNHITMLLRNPYVLSEEEEEGEDADLEKEETEEPKGKKKKNKSKQLKKPQKNKPSLVDVDLSLSAYANAKKYYDHKRHAAKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTVTTIQKARKVYWFEKFLWFISSENYLVIAGRDQQQNELIVKRYLKPGDIYVHADLHGATSCVIKNPTGEPIPPRTLTEAGTMALCYSAAWDARVVTSAWWVSHNQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHREERKIKVQDEDLETVSSSASELVAEEVELLEGGDSSSEEDKAECHEAPEDVEATPENNGDENVADLDQDRVSTPPVPEGVSDEDDGESEVEQPEPKSEVKEEEVNYPDTTIDLSHLQSQRSLQKTIPKEEEPNLSDSKSQGRRHLSAKERREMKKKKQQSDSENLDPPEERQKDTETQRPPPPNTNKGVPAPQPIKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKEEQAKKQQQKSKAVHRSAGGGKEMMPGVVVLHESEDLAPEEQQDEKDEQDQDQPGVEDGTALLDSLTGQPHAEDILLFAVPICAPYTAMTNYKYKVKLTPGTQKKGKAAKIALHNFMQSKEATAREKDLFRSVKDTDLSRNIPGKVKVSAPNLLNRKKK", "length": 1071, "header": "tr|A0A8V0Z307-1|A0A8V0Z307_CHICK Isoform 1 of Ribosome quality control complex subunit NEMF OS=Gallus gallus OX=9031 GN=NEMF PE=1 SV=1 CANONICAL=A0A8V0Z307-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z307-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z307/entry#A0A8V0Z307-1", "sequence": { "sequence": "MKSRFSTVDIRALVAELRLSLLGMRVNNVYDVDSKTYLIRLQKPDCKATLLLESGIRIHTTEFEWPKNMMPSGFAMKCRKHLKTRRLVSVRQLGIDRIVDFQFGSNEAAYHLIIELYDRGNIVLTDHEYLILNILRFRTDEADDVRFAVRERYPVDSAKAPTPLPTLERLTEIISNAPKGEQLKRVLNPHLPYGATLIEHCLIEAGFSGYVKIDQHMESKENIEKVLSALEKAEGYMTLTEDFSGKGYIIQKKEKKPSLEPDKPAEDIYTYEEFHPFLFSQHSKCPYLEFDSFNKAADEFYSKLEGQKIDLKALQQEKQALKKLENVRRDHEQRLEALQQAQEVDKIKGELIEMNLEIVSRAIQVVRSALANQIDWTEIGAIVKEAQAQGDPVANAIKELKLQTNHITMLLRNPYVLSEEEEEGEDADLEKEETEEPKGKKKKNKSKQLKKPQKNKPSLVDVDLSLSAYANAKKYYDHKRHAAKKTQKTVEAAEKAFKSAEKKTKQTLKEVQTVTTIQKARKVYWFEKFLWFISSENYLVIAGRDQQQNELIVKRYLKPGDIYVHADLHGATSCVIKNPTGEPIPPRTLTEAGTMALCYSAAWDARVVTSAWWVSHNQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHREERKIKVQDEDLETVSSSASELVAEEVELLEGGDSSSEEDKAECHEAPEDVEATPENNGDENVADLDQDRVSTPPVPEGVSDEDDGESEVEQPEPKSEVKEEEVNYPDTTIDLSHLQSQRSLQKTIPKEEEPNLSDSKSQGRRHLSAKERREMKKKKQQSDSENLDPPEERQKDTETQRPPPPNTNKGVPAPQPIKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKEEQAKKQQQKSKAVHRSAGGGKEMMPGVVVLHESEDLAPEEQQDEKDEQDQDQPGVEDGTALLDSLTGQPHAEDILLFAVPICAPYTAMTNYKYKVKLTPGTQKKGKAAKIALHNFMQSKEATAREKDLFRSVKDTDLSRNIPGKVKVSAPNLLNRKKK", "length": 1071, "header": "tr|A0A8V0Z307-1|A0A8V0Z307_CHICK Isoform 1 of Ribosome quality control complex subunit NEMF OS=Gallus gallus OX=9031 GN=NEMF PE=1 SV=1 CANONICAL=A0A8V0Z307-1" }, "locus": { "chromosome": "5", "start_pos": 57456614, "end_pos": 57436592, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046376.1", "url": "https://www.ensembl.org/id/ENSGALT00010046376.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027613.1", "url": "https://www.ensembl.org/id/ENSGALP00010027613.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9954709", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9954709", "resource": "Reactome", "description": "Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z307", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z307" } ], "pmid": "" }, { "name": "nuclear export", "id": "GO:0051168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051168", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z307", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z307" } ], "pmid": "" }, { "name": "ribosome-associated ubiquitin-dependent protein catabolic process", "id": "GO:1990116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990116", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z307", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z307" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z307", "url": 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"MGEHRDAPPSPTPIIQADSHPLREAQRKAATNVAAINPMGTRYSLYARTRLGFLFYKRQVKKARERFPHGHSVSQPLGFRGVKIVPIPVLSNNYSYLVIDTDSGRAAVVDPSDPLAVQAAIEEEGVMLEAILCTHKHWDHSGGNAALLQQHGSCKVYGSAVDAIPELTHPVGDREKLSVGCLTFEALATPGHTVGHVAFVLDAGPFGGPPCLFSGDLLFLAGCGRLFEGSPETMLASLDAAVGLGEDTLLWPGHEYALECLSFARLLELDNPALEQKLLWATQQRQEKRSTCPSTLGEERTYNPFLRTHRRELQEALGLQRGSGEHHDAFRARVLREVRRRKDLYKAT", "length": 348, "header": "tr|A0A8V0Z312-1|A0A8V0Z312_CHICK Isoform 1 of PNKD metallo-beta-lactamase domain containing OS=Gallus gallus OX=9031 GN=PNKD PE=1 SV=1 CANONICAL=A0A8V0Z312-1" }, "locus": { "chromosome": "7", "start_pos": 22183172, "end_pos": 22179523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046386.1", "url": "https://www.ensembl.org/id/ENSGALT00010046386.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027618.1", "url": "https://www.ensembl.org/id/ENSGALP00010027618.1" } ] } }, { "isoform_ac": "A0A8V0Z8W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z312/entry#A0A8V0Z8W2-1", "sequence": { "sequence": "MALAGPLLFRLGYSLYARTRLGFLFYKRQVKKARERFPHGHSVSQPLGFRGVKIVPIPVLSNNYSYLVIDTDSGRAAVVDPSDPLAVQAAIEEEGVMLEAILCTHKHWGCTELLTCRDHSGGNAALLQQHGSCKVYGSAVDAIPELTHPVGDREKLSVGCLTFEALATPGHTVGHVAFVLDAGPFGGPPCLFSGDLLFLAGCGRLFEGSPETMLASLDAAVGLGEDTLLWPGHEYALECLSFARLLELDNPALEQKLLWATQQRQEKRSTCPSTLGEERTYNPFLRTHRRELQEALGLQRGSGEHHDAFRARVLREVRRRKDLYKAT", "length": 327, "header": "tr|A0A8V0Z8W2-1|A0A8V0Z312_CHICK Computationally mapped isoform of PNKD metallo-beta-lactamase domain containing OS=Gallus gallus OX=9031 GN=PNKD PE=1 SV=1 CANONICAL=A0A8V0Z312-1" }, "locus": { "chromosome": "7", "start_pos": 22181913, "end_pos": 22179523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046380.1", "url": "https://www.ensembl.org/id/ENSGALT00010046380.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027615.1", "url": "https://www.ensembl.org/id/ENSGALP00010027615.1" } ] } }, { "isoform_ac": "A0A8V0Z9K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z312/entry#A0A8V0Z9K4-1", "sequence": { "sequence": "MALAGPLLFRLGYSLYARTRLGFLFYKRQVKKARERFPHGHSVSQPLGFRGVKIVPIPVLSNNYSYLVIDTDSGRAAVVDPSDPLAVQAAIEEEGVMLEAILCTHKHWDHSGGNAALLQQHGSCKVYGSAVDAIPELTHPVGDREKLSVGCLTFEALATPGHTVGHVAFVLDAGPFGGPPCLFSGDLLFLAGCVMVAVCLAAGRLFEGSPETMLASLDAAVGLGEDTLLWPGHEYALECLSFARLLELDNPALEQKLLWATQQRQEKRSTCPSTLGEERTYNPFLRTHRRELQEALGLQRGSGEHHDAFRARVLREVRRRKDLYKAT", "length": 327, "header": "tr|A0A8V0Z9K4-1|A0A8V0Z312_CHICK Computationally mapped isoform of PNKD metallo-beta-lactamase domain containing OS=Gallus gallus OX=9031 GN=PNKD PE=1 SV=1 CANONICAL=A0A8V0Z312-1" }, "locus": { "chromosome": "7", "start_pos": 22181913, "end_pos": 22179523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046384.1", "url": "https://www.ensembl.org/id/ENSGALT00010046384.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027617.1", "url": "https://www.ensembl.org/id/ENSGALP00010027617.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 12, "start_aa": "Thr", "end_pos": 12, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr12", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 189, "start_aa": "Thr", "end_pos": 189, "end_aa": "Thr", "residue": "Thr", "site_lbl": 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[ { "database": "UniProtKB", "id": "A0A8V0Z312", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z312" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione", "id": "GO:0019243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019243", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z312", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z312" } ], "pmid": "" }, { "name": "negative regulation of neurotransmitter secretion", "id": "GO:0046929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046929", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z312", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z312" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z312", "url": 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This record is derived from a genomic sequence (NC_052578.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046776652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046776652" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z314", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z314" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "R3HCC1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z314", "locus": { "chromosome": "6", "start_pos": 23053394, "end_pos": 23059509, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017790", "url": "https://www.ensembl.org/id/ENSGALG00010017790" } ] } } ], "crossref": [ { "id": "A0A8V0Z314", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z314", "database": 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"Protein Classification" ] }, { "id": "PTHR21678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21678:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21678:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_046776652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046776652", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z314", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z314", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z314-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z314-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3J3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMKNKSPPGRGSLAQPQPIARISRCASRWHHRGMGTVAVTLLSLAGGGGTMEAEGSRVRRRKPDMALYVPKARRERAAQEAAASHREPEKQRPALDIPKGGSEGQRRSPGARTHVGRAAGRESKAGATEPRAASAGDRQAAGASPTVQEPSLEPAAAQPPGRASRDAGHGEHSHGVRTVPDPLGAHPVAASEHRGDPDVCNDGVMAAELSTVRRTELGNVMELLGDSSLGAATERSGCTEQGALQQAGEGNVDSTPQLSWESVKSHEEERERDESVLAGQSEGCSTDPEEERQGGSAVAAPGGAACEAGTGDTPAFLGWDMGSTSQLLPEHVEQLPPSKEQASAGAGHDGEEGVLVPDGSSELGAGEEMSCTGGTESGSGETESGSGDGDPLGSPQPPKPLELLCHGIEQLSPGSWAEEPARADEDEGWQRQHREEEEDEEGCPHGSSLKPSQPGAGTPSSPGGAESWDALFNDDGDCLDPRLLEELSGGSERQQSLQEPRFNYYGAEPAAPDLSDAELPHVIEIYDFPPDFRTEDLMRIFCSYQKKGFDIKWVDDTHALGIFSSPITARDALSTKHLMVKTRPLSQGTRAAKAKARAYADFLQPAKERPETSAALARRLVIGALGVRSSQTPAQRDAERRKLQEARERKRLENKQREDAWEGRE", "length": 665, "header": "tr|A0A8V0Z314-1|A0A8V0Z314_CHICK Isoform 1 of R3H domain and coiled-coil containing 1 like OS=Gallus gallus OX=9031 GN=R3HCC1L PE=4 SV=1 CANONICAL=A0A8V0Z314-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z314-1", "url": 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"MQHHLLWRVRQGGGGTMEAEGSRVRRRKPDMALYVPKARRERAAQEAAASHREPEKQRPALDIPKGGSEGQRRSPGARTHVGRAAGRESKAGATEPRAASAGDRQAAGASPTVQEPSLEPAAAQPPGRASRDAGHGEHSHGVRTVPDPLGAHPVAASEHRGDPDVCNDGVMAAELSTVRRTELGNVMELLGDSSLGAATERSGCTEQGALQQAGEGNVDSTPQLSWESVKSHEEERERDESVLAGQSEGCSTDPEEERQGGSAVAAPGGAACEAGTGDTPAFLGWDMGSTSQLLPEHVEQLPPSKEQASAGAGHDGEEGVLVPDGSSELGAGEEMSCTGGTESGSGETESGSGDGDPLGSPQPPKPLELLCHGIEQLSPGSWAEEPARADEDEGWQRQHREEEEDEEGCPHGSSLKPSQPGAGTPSSPGGAESWDALFNDDGDCLDPRLLEELSGGSERQQSLQEPRFNYYGAEPAAPDLSDAELPHVIEIYDFPPDFRTEDLMRIFCSYQKKGFDIKWVDDTHALGIFSSPITARDALSTKHLMVKTRPLSQGTRAAKAKARAYADFLQPAKERPETSAALARRLVIGALGVRSSQTPAQRDAERRKLQEARERKRLENKQREDAWEGRE", "length": 631, "header": "tr|A0A8V0Z3J3-1|A0A8V0Z3J3_CHICK Computationally mapped isoform of R3H domain and coiled-coil containing 1 like OS=Gallus gallus OX=9031 GN=R3HCC1L PE=4 SV=1 CANONICAL=A0A8V0Z314-1" }, "locus": { "chromosome": "6", "start_pos": 23059310, "end_pos": 23053685, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042986.1", "url": "https://www.ensembl.org/id/ENSGALT00010042986.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025476.1", "url": "https://www.ensembl.org/id/ENSGALP00010025476.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 313, "start_aa": "Thr", "end_pos": 313, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr313", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z322-1", "uniprot_ac": "A0A8V0Z322", "uniprot_id": "A0A8V0Z322_CHICK", "mass": { "chemical_mass": 26559.0, "monoisotopic_mass": 26559.0 }, "refseq": { "ac": "XP_040556316", "name": "T-cell surface glycoprotein CD8 alpha chain-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040556316" }, "gene_names": [ { "name": "LOC107049168", "type": "recommended", "evidence": [ { "id": "A0A8V0Z322", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z322" } ] }, { "name": "LOC107049168", "type": "synonym", "evidence": [ { "id": "XP_040556316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040556316" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z322", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z322/entry#names_and_taxonomy" } ] }, { "name": "T-cell surface glycoprotein CD8 alpha chain-like", "type": "synonym", "evidence": [ { "id": "XP_040556316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040556316" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040556316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040556316" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z322", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z322" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107049168", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z322", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z322", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z322", "database": "AlphaFoldDB", "categories": [] }, { "id": "107049168", "url": "https://www.ncbi.nlm.nih.gov/gene/107049168", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007110", "url": 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}, { "id": "PTHR10441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10441:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10441:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_040556316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040556316", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z322", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z322", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z322-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z322-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGSPALLLLLSFGLCCTSTQAQKKMMEARFLNRNIKHPIEGQRLELECLHYERNRPIFWIRLDKSGNLHFIVSSTHSYSTTLQEGEKTPPNFEALWRGNSYRLVVKSFRAQDQGIYFCINYINPVLHFSSGQPAFFPVTTTAAPTTPAATTPSSQATKKDNSLQSPDAAEHITPTAITRSSQVTTKDSPQQGRDAGTSNENTLHFCYDGVIWVNLAGACLLLLTAITITITHCQRPSSP", "length": 240, "header": "tr|A0A8V0Z322-1|A0A8V0Z322_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107049168 PE=4 SV=1 CANONICAL=A0A8V0Z322-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z322-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z322/entry#A0A8V0Z322-1", "sequence": { "sequence": "MAGSPALLLLLSFGLCCTSTQAQKKMMEARFLNRNIKHPIEGQRLELECLHYERNRPIFWIRLDKSGNLHFIVSSTHSYSTTLQEGEKTPPNFEALWRGNSYRLVVKSFRAQDQGIYFCINYINPVLHFSSGQPAFFPVTTTAAPTTPAATTPSSQATKKDNSLQSPDAAEHITPTAITRSSQVTTKDSPQQGRDAGTSNENTLHFCYDGVIWVNLAGACLLLLTAITITITHCQRPSSP", "length": 240, "header": "tr|A0A8V0Z322-1|A0A8V0Z322_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107049168 PE=4 SV=1 CANONICAL=A0A8V0Z322-1" }, "locus": { "chromosome": "4", "start_pos": 85420222, "end_pos": 85416498, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046405.1", "url": "https://www.ensembl.org/id/ENSGALT00010046405.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027628.1", "url": "https://www.ensembl.org/id/ENSGALP00010027628.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:100857206", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:100857206", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z322", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z322" } ], "pmid": "" }, { "name": "T cell 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"type": "recommended", "evidence": [ { "id": "A0A8V0Z324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324" } ] } ], "protein_names": [ { "name": "Family with sequence similarity 83 member G", "type": "synonym", "evidence": [ { "id": "A0A8V0Z324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z324", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FAM83G", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324", "locus": { "chromosome": "14", "start_pos": 5150673, "end_pos": 5164175, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017793", "url": "https://www.ensembl.org/id/ENSGALG00010017793" } ] } } ], "crossref": [ { "id": "A0A8V0Z324", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z324", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09187", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09187", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101751551", "url": "https://www.ncbi.nlm.nih.gov/gene/101751551", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:101751551", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751551", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z324-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3J8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3J8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFSQVQCLDDSHVNWRSSESKPEFFYSEEQRLALEALAARGPDAFYEVLKKENIRDFLSELELKKILDTLETYDPGSEYIPRHGSGTAGSEGDRNSQGDEQEVAPSLEYWPQRSDRSIPQLDLGWPETIAYRGVTRATVYMQPPIEGQAHIKEVVRKMICQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVGVYIILDETNVKHFLQMCERAQMHTGHMKNLRVRSTGGTEFFTRSATKFKGALAQKFMFVDGDRAMCGSYSFTWSAARTDRNVITVLSGQVVEAFDKQFQELYLMSKGVSLKSISMGMEPEPEPVTLPSVVPVTPANAMVKKLINPKYALVKAKSADQISKTSSENQDKTQKVENKGKGLHEGQAGDRHGEAADLSLLIHPGLLNLEKANMFDYLPTWVEPDPEPGSEVLGYINIIDPKIKNVKLSQMNRIKVCDISQASAQHRQMLKNRELEAKKISTQEPPLVSPCQRQTPQVPTEAPVVPATSPIEGNGWLTKQVGTSATQPLSHHLKPPEETPEEAKPPVPKPRTVPVGGLATKATTPCDSSSAPEGDTQPPLADHVDARQEPKESPNTASPNSCHLPAVGTQEDKGPPCAHNGLGEEEEEEEEEYITLSDQESCSSSSADHSYRRSNASSISDEYFEVRERYGPLRRTNSDVTHNGEFVPIQRKLSDPHISRGTFLSPLGSLPSLKHIRVEDMAKRRSNAVEIRCVLPRTILDGNGSYPTSATQGIEGISPESTRRSLPRASLQHSSPHCAAQSAQGTHIYRYRPRNLTGKEQGKEPSCSPPCEKPPGASKHRRDSTEPKKTIAGSQPYWQGKAFSPSKPRAVSKALSSLPESQKAAEEMRTPLGIPLSKLSQSKHLKNKVTAAPGATDSKKKPPEPTSQKEQ", "length": 900, "header": "tr|A0A8V0Z324-1|A0A8V0Z324_CHICK Isoform 1 of Family with sequence similarity 83 member G OS=Gallus gallus OX=9031 GN=FAM83G PE=3 SV=1 CANONICAL=A0A8V0Z324-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z324-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324/entry#A0A8V0Z324-1", "sequence": { "sequence": "MAFSQVQCLDDSHVNWRSSESKPEFFYSEEQRLALEALAARGPDAFYEVLKKENIRDFLSELELKKILDTLETYDPGSEYIPRHGSGTAGSEGDRNSQGDEQEVAPSLEYWPQRSDRSIPQLDLGWPETIAYRGVTRATVYMQPPIEGQAHIKEVVRKMICQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVGVYIILDETNVKHFLQMCERAQMHTGHMKNLRVRSTGGTEFFTRSATKFKGALAQKFMFVDGDRAMCGSYSFTWSAARTDRNVITVLSGQVVEAFDKQFQELYLMSKGVSLKSISMGMEPEPEPVTLPSVVPVTPANAMVKKLINPKYALVKAKSADQISKTSSENQDKTQKVENKGKGLHEGQAGDRHGEAADLSLLIHPGLLNLEKANMFDYLPTWVEPDPEPGSEVLGYINIIDPKIKNVKLSQMNRIKVCDISQASAQHRQMLKNRELEAKKISTQEPPLVSPCQRQTPQVPTEAPVVPATSPIEGNGWLTKQVGTSATQPLSHHLKPPEETPEEAKPPVPKPRTVPVGGLATKATTPCDSSSAPEGDTQPPLADHVDARQEPKESPNTASPNSCHLPAVGTQEDKGPPCAHNGLGEEEEEEEEEYITLSDQESCSSSSADHSYRRSNASSISDEYFEVRERYGPLRRTNSDVTHNGEFVPIQRKLSDPHISRGTFLSPLGSLPSLKHIRVEDMAKRRSNAVEIRCVLPRTILDGNGSYPTSATQGIEGISPESTRRSLPRASLQHSSPHCAAQSAQGTHIYRYRPRNLTGKEQGKEPSCSPPCEKPPGASKHRRDSTEPKKTIAGSQPYWQGKAFSPSKPRAVSKALSSLPESQKAAEEMRTPLGIPLSKLSQSKHLKNKVTAAPGATDSKKKPPEPTSQKEQ", "length": 900, "header": "tr|A0A8V0Z324-1|A0A8V0Z324_CHICK Isoform 1 of Family with sequence similarity 83 member G OS=Gallus gallus OX=9031 GN=FAM83G PE=3 SV=1 CANONICAL=A0A8V0Z324-1" }, "locus": { "chromosome": "14", "start_pos": 5163590, "end_pos": 5151677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042994.1", "url": "https://www.ensembl.org/id/ENSGALT00010042994.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025484.1", "url": "https://www.ensembl.org/id/ENSGALP00010025484.1" } ] } }, { "isoform_ac": "A0A8V0Z3J8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324/entry#A0A8V0Z3J8-1", "sequence": { "sequence": "MAFSQVQCLDDSHVNWRSSESKPEFFYSEEQRLALEALAARGPDAFYEVLKKENIRDFLSELELKKILDTLETYDPGSEYIPRHGSGTAGSEGDRNSQGDEQEVAPSLEYWPQRSDRSIPQLDLGWPETIAYRGVTRATVYMQPPIEGQAHIKEVVRKMICQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVGVYIILDETNVKHFLQMCERAQMHTGHMKNLRVRSTGGTEFFTRSATKFKGALAQKFMFVDGDRAMCGSYSFTWSAARTDRNVITVLSGQVVEAFDKQFQELYLMSKGVSLKSISMGMEPEPEPVTLPSVVPVTPANAMVKKLINPKYALVKAKSADQISKTSSENQDKTQKVENKGKGLHEGQAGDRHGEAADLSLLIHPGLLNLEKANMFDYLPTWVEPDPEPGSEVLGYINIIDPKIKNVKLSQMNRIKVCDISQASAQHRQMLKNRELEAKKISTQEPPLVSPCQRQTPQVPTEAPVVPATSPIEGNGWLTKQVGTSATQPLSHHLKPPEETPEEAKPPVPKPRTVPVGGLATKATTPCDSSSAPEGDTQPPLADHVDARQEPKESPNTASPNSCHLPAVGTQEDKGPPCAHNGLGEEEEEEEEEYITLSDQESCSSSSADHSYRRSNASSISDEYFEVRERYGPLRRTNSDVTHNGEFVPIQRKLSDPHISRGTFLSPLGSLPSLKHIRVEDMAKRRSNAVEIRCVLPRTILDGNGSYPTSATQGTHIYRYRPRNLTGKEQGKEPSCSPPCEKPPGASKHRRDSTEPKKTIAGSQPYWQGKAFSPSKPRAVSKALSSLPESQKAAEEMRTPLGIPLSKLSQSKHLKNKVTAAPGATDSKKKPPEPTSQKEQ", "length": 868, "header": "tr|A0A8V0Z3J8-1|A0A8V0Z3J8_CHICK Computationally mapped isoform of Family with sequence similarity 83 member G OS=Gallus gallus OX=9031 GN=FAM83G PE=3 SV=1 CANONICAL=A0A8V0Z324-1" }, "locus": { "chromosome": "14", "start_pos": 5163590, "end_pos": 5151677, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042991.1", "url": "https://www.ensembl.org/id/ENSGALT00010042991.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025481.1", "url": "https://www.ensembl.org/id/ENSGALP00010025481.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 326, "start_aa": "Thr", "end_pos": 326, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr326", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:101751551", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:101751551", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9S0Z9-1", "protein_name": "Family with sequence similarity 83 member G", "gene_name": "FAM83G", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFSQVQCLDDSHVNWRSSEAKPEFFYSEEQRLALEALAANGRDAFYEVLKRENIRDFLSELELRRILETIEVYDPGSEDPRAGTQPRGPEDGDAASAAEGTPTEAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERARMHLGHLKNLRVRSSGGTEFFTRSATKFKGALAQKFMFVDGDRAICGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSHSVCLKDIPMEKEPEPEPIVLPPSVPLVPSGTVAKKLVNPKYALVKAKSADEIAKSSSEKQDTAKPAGVRGAVLAERPGDLPEPPLPVHPGLLNLERANMFDYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQAGTQLWRQSQDPGPALQSSAPPDGIPAENSLPQGDAQPRPPVPKPRTVPVADLLAQEGGGAGWALETPEEESPHNGMDHGLSRTVGPGHAALQRQLPVTPDDPDGEGQVVPNGLDGEEEEDDDDYVTLSDQDSLSGSSDHGPGPRRASLASSSVSDEYFEVTDRSACLRRRHSEQVANGPAQAPRRQLSAPHMTRGTCGGALGDSSWAQGQEREEAGAQRRMQAARPVDQEAQILKVVASADRPSCCPRGTVHLKLQPRRDQVRSSTARVGRPRALPVCVQTSSCSGRGQRFHHYGAPASGTREKDGFPRPLRTLGPPQFRPTADSAQSSSRKAGPAMAGPQHWQAKSGPGPRMLPGPGSPRPARNASALANSRATEEHPSPFGIPYSKLSQSKHLKARTGGSQWAPSDSKRRAHAPRDHKDP", "length": 872 }, "evidence": [ { "id": "A0A8V0Z324", "url": "https://omabrowser.org/oma/group/A0A8V0Z324/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A6ND36-1", "protein_name": "Protein FAM83G", "gene_name": "FAM83G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRSATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSHSVSLKGIPMEKEPEPEPIVLPSVVPLVPAGTVAKKLVNPKYALVKAKSVDEIAKISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEPSAPQDGVPAENGLPQGDPEPLPPVPKPRTVPVADVLARDSSDIGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDDDDYVTLSDQDSHSGSSGRGPGPRRPSVASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFVGPQGGSPWAQSRGREEADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRYRSAADSVQSSTRNAGPAMAGPHHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRATEEHPSPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPRDRKDP", "length": 823 }, "evidence": [ { "id": "A0A8V0Z324", "url": "https://omabrowser.org/oma/group/A0A8V0Z324/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZN30-1", "protein_name": "Family with sequence similarity 83, member G", "gene_name": "Fam83g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVAQGRDAFYEVLKRENIRDFLSELELSRIVEAIEVYDPGSEDPRVSGRRSELQDNGGVDASEDTSAAGGPPATAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQPHIKEVVRKMVSQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERARMHLGHLKNLRVRSSGGTEFFTRSATKFKGVLAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSQSVSLKDIPMEKEPEPEPIVLPSVVPLVPTGTMAKKLVNPKYALVKAKSVDEIAKTSSDKQEVTRPPGLRGPAVAERPGDLSELLPPVHPGLLNLERANMFEYLPTWVEPDPEPGSDILGYINIIDPKIWNPQPNQMNRIKIRDTAHASTQHQLWKQSQGARPCPEPCLPPAPRDSQDIVPAENGFSQGNSEPQAPVPKPRTVPVASVLAQDGSDIGWALDTPEKETPQNGIDPKLPSTTSESQVPQQQQLPVTQDDPDDLETGLPNGLYEDEDEDDDDYVTLSDQDSLSGSSGPGPGHRRPSVASSMSDEYFEVRERSVPLQRRHSEQVANGPSHPPRRQLSAPHVTRGTFGGPLSGPLWAQGRGREDIDASRIQAQRPVDRQAQGQHFHRHGSTTSRTPGPPRYRPAADGTQSSSKKASPATAGPNHWQPKGSPTPRMLPDPGSPRPTRNTRLRAELRATEEHPSPFGIPYSKLSQSKHLKARAGGSQWVPSDSKRRARDHKEP", "length": 814 }, "evidence": [ { "id": "A0A8V0Z324", "url": "https://omabrowser.org/oma/group/A0A8V0Z324/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SB20-1", "protein_name": "Family with sequence similarity 83 member G", "gene_name": "FAM83G", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFSQVQCLDDSHVNWRSSESKPEFFYSEEQRLALEALVARGPDAFYEVLKRENIRDFLSELELRRILEAIEVYDPGSEDPRAGGQPRGPEDSGGGQGGDEASAADGAPTEAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVVAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESSVKYFLHMCARARMHPGHLKNLRVRSSGGTEFFTRSATKFKGALAQKFMFVDGDRAICGSYSFTWSAARTDRNVISVLSGQVVEVFDRQFQELYLTSHSVSLKGVPMEKEPEPEPIVLPSVVPLVPSGTMAKKLVNPKYALVKAKSADELAKTSSEKQEATRPLGARGPDPAERPAELPEPPPPIHPGLLNLERANMFEYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQAWRQSQDSSAGPANGVPAQNGLPQGDAEPRPPVPKPRTVPVADLLARDGGGLGWALESPEEEAPQHSTDLGPPRTAGPGPGPLQRQLSTDAPDGQGAAVPNGLDGEEEEEEDDDDYVTLSDQDSLSGSSGRGPGPRRPSVASSSVSDEYFEVTERSATLRRRHSEQVANGPAQPPRRQLSAPHLTRGTFAGPLGGPSWAQGREREEAGTLTRMQAPRSADKEAQGLRFHHYGVSGARDKDGFSRPLRTPGPPRYRPAADSAQSSSRKVGPAVAGPQRWQAKAGPVPRTLVGPGSPGLARNASPPADGRAAEERPSPFGIPYSKLSQAKHLKARTGAGQWASSDSKRRAQAPQDHKEP", "length": 812 }, "evidence": [ { "id": "A0A8V0Z324", "url": "https://omabrowser.org/oma/group/A0A8V0Z324/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5SWY7-1", "protein_name": "Protein FAM83G", "gene_name": "Fam83g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELSRIVEAIEVYDPGSEDPRVSGRRPEPQDNGGADASEETSAAGGPPATETLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQPHIKEVVRKMVSQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERARMHLGHLKNLRVRSSGGTEFFTRSATKFKGVLAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSQSVSLKDIPMEKEPEPEPIVLPSVVPLVPTGTMAKKLVNPKYALVKAKSVDEIAKSSSDKQEVTRPPGLRGPAVAERPGDLSELLPPVHPGLLNLERANMFEYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPNQMNRIKIRDTAHASAQHQLWKQSQGARPCPAPCPPPAPRDSQGVVPAENGFPQGNPEPQAPVPKPRTVPVASVLARDGSDIGWALDTPEKETPQNGIDPRLPSTASESEVPQQQHSSMTQDDPDGLERGLPNGLDEDEDDDDDYVTLSDQDSLSGSSGPGPGHRRPSVASSMSDEYFEVRERSVPLQRRHSEQMANGPGHPPRRQLSAPHVTRGTFGGPLSSPLWAQGRSREDVDASRIQGQRPMDRQAQGQHFHRHGSTTSRTPGPPRFRPAADGTQSSSKKASPAAAGPHHWQPKGSPTPRMLPDPGSPRPTRNTRLRAELRATEEHASPFGIPYSKLSQSKHLKARAGGSQWAPSDSKRRARDHKEP", "length": 812 }, "evidence": [ { "id": "A0A8V0Z324", "url": "https://omabrowser.org/oma/group/A0A8V0Z324/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z324", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z324", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z324", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z324", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "BMP signaling pathway", "id": "GO:0030509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z324", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 784, "end_pos": 786, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z324", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z324" }, { "id": "PF07894", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Scaffolding anchor of CK1", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 299, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 136, 326 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 644, "end_pos": 646 }, { "start_pos": 732, "end_pos": 734 }, { "start_pos": 784, "end_pos": 786 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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} ], "protein_names": [ { "name": "Mex-3 RNA binding family member B", "type": "synonym", "evidence": [ { "id": "A0A8V0Z344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z344/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein MEX3B", "type": "synonym", "evidence": [ { "id": "XP_015147519", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147519" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147519", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147519" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z344", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z344" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MEX3B", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z344", "locus": { "chromosome": "10", "start_pos": 11789375, "end_pos": 11785748, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016519", "url": "https://www.ensembl.org/id/ENSGALG00010016519" } ] } } ], "crossref": [ { "id": "A0A8V0Z344", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z344", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16721", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16721", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22423", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22423", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22424", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22424", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107054196", "url": "https://www.ncbi.nlm.nih.gov/gene/107054196", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047226", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047226", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:107054196", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107054196", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFERGPA", "url": "https://omabrowser.org/oma/group/QFERGPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z344", "url": "https://www.orthodb.org/?gene=A0A8V0Z344", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23285", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23285", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23285:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23285:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015147519", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147519", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z344", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z344", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z344-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z344-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSSLFADMERNGSGGGGGGGGGGGGETLDDQRALQIALDQLSLLGLDNDEAGSIYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPLFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGTVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIAMRTGGIIELTDENDFHANGTDVGFELNGTGSLWSKPTPPSITPTPGRKPFCNYRNDSSSSLGSASTDSYFGGGTGGGGARLADYSPPSPALSFTHNGNNNNNSANGYVYGGGGGDVLSSPDCCSELPFDSPPGFDLAPAPPPGAALLWPQFERGPAAAPPSPAPSPAAAAFPGAAPANANLALLVSGPRRGGSAPPPARLSPPLHGSAAAAGPEHPLARRVRSDPGGRLLAASYPLYANGLGGHLPGLPSDSSASSSSSSSSSSSSSCSSSGVRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKTEPQCPVCHSAVTQAIRIFS", "length": 559, "header": "tr|A0A8V0Z344-1|A0A8V0Z344_CHICK Isoform 1 of Mex-3 RNA binding family member B OS=Gallus gallus OX=9031 GN=MEX3B PE=4 SV=1 CANONICAL=A0A8V0Z344-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z344-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z344/entry#A0A8V0Z344-1", "sequence": { "sequence": "MPSSLFADMERNGSGGGGGGGGGGGGETLDDQRALQIALDQLSLLGLDNDEAGSIYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPLFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGTVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIAMRTGGIIELTDENDFHANGTDVGFELNGTGSLWSKPTPPSITPTPGRKPFCNYRNDSSSSLGSASTDSYFGGGTGGGGARLADYSPPSPALSFTHNGNNNNNSANGYVYGGGGGDVLSSPDCCSELPFDSPPGFDLAPAPPPGAALLWPQFERGPAAAPPSPAPSPAAAAFPGAAPANANLALLVSGPRRGGSAPPPARLSPPLHGSAAAAGPEHPLARRVRSDPGGRLLAASYPLYANGLGGHLPGLPSDSSASSSSSSSSSSSSSCSSSGVRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKTEPQCPVCHSAVTQAIRIFS", "length": 559, "header": "tr|A0A8V0Z344-1|A0A8V0Z344_CHICK Isoform 1 of Mex-3 RNA binding family member B OS=Gallus gallus OX=9031 GN=MEX3B PE=4 SV=1 CANONICAL=A0A8V0Z344-1" }, "locus": { "chromosome": "10", "start_pos": 11788371, "end_pos": 11785947, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039786.1", "url": "https://www.ensembl.org/id/ENSGALT00010039786.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023023.1", "url": "https://www.ensembl.org/id/ENSGALP00010023023.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 264, "start_aa": "Thr", "end_pos": 264, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr264", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 271, "start_aa": "Thr", "end_pos": 271, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr271", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:107054196", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107054196", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MZR0-1", "protein_name": "Mex-3 RNA binding family member B", "gene_name": "MEX3B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSSLFADLERNGSGGGGGGGGGGGGGGGGGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGAGTSGSAAATPRLADYSPPSPALSFAHNGNNNNNGNGYTYAAAAAAGGEASVPSPDGCPELPPAFDPAPAPPPGAPLLWAQFERSPGGGPAAPASSSCSSSASSSAASSSSVVFPGGGASAPSSANLGLPVHRRLHPGASCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPAGLQPSSSDASGSSSSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTAVTQAIRIFS", "length": 588 }, "evidence": [ { "id": "A0A8V0Z344", "url": "https://omabrowser.org/oma/group/A0A8V0Z344/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZFL6-1", "protein_name": "Mex-3 RNA binding family member B", "gene_name": "Mex3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSSLFADLERNGSGGGGGGGGGGGGSGSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSGSTAATSRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGEASVPSPDGGTELQPTFDPAPAPPPGTPLLWAQFERSPGGGSAAPVSSSCSSSASSSASSSSVVFPGGGASSTPSNANLGLLVHRRLHPGTSCPRLSPPLHMATGAGEHHLARRVRSDPGGGGLAYAAYANGLGTQLPGLPSSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTAVTQAIRIFS", "length": 576 }, "evidence": [ { "id": "A0A8V0Z344", "url": "https://omabrowser.org/oma/group/A0A8V0Z344/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q69Z36-1", "protein_name": "RNA-binding protein MEX3B", "gene_name": "Mex3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSSLFADLERNGSGGGGGGGGGGGGGGSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGGSGRDGDRRGFSISPTPSLEPWLPGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSGSAAATSRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGEASVPSPDGGPELQPTFDPAPAPPPGTPLLWAQFERSPGGGSAAPVSSSCSSSASSSASSSSVVFPGGGASSTPSNANLGLLVHRRLHPGTSCPRLSPPLHMATGAGEHHLARRVRSDPGGGGLAYAAYANGLGTQLPGLPSSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTAVTQAIRIFS", "length": 601 }, "evidence": [ { "id": "A0A8V0Z344", "url": "https://omabrowser.org/oma/group/A0A8V0Z344/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZN04-1", "protein_name": "RNA-binding protein MEX3B", "gene_name": "MEX3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSSLFADLERNGSGGGGGGSSGGGETLDDQRALQLALDQLSLLGLDSDEGASLYDSEPRKKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVAMARREIISAAEHFSMIRASRNKNTALNGAVPGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGMPENVDRAREEIEAHIALRTGGIIELTDENDFHANGTDVGFDLHHGSGGSGPGSLWSKPTPSITPTPGRKPFSSYRNDSSSSLGSASTDSYFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEASVPSPDGCPELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGASAPSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANGLGAQLPGLQPSDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTAVTQAIRIFS", "length": 569 }, "evidence": [ { "id": "A0A8V0Z344", "url": "https://omabrowser.org/oma/group/A0A8V0Z344/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z344", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z344" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z344", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z344" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z344", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z344" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z344", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z344" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z344", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z344" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 508, "end_pos": 548, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 264, 271 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 149, "end_pos": 151 }, { "start_pos": 245, "end_pos": 247 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z352-1", "uniprot_ac": "A0A8V0Z352", "uniprot_id": "A0A8V0Z352_CHICK", "mass": { "chemical_mass": 9279.0, "monoisotopic_mass": 9279.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z352", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z352/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z352", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z352" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z352", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z352", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z352", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0Z352", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z352", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z352-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z352-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVIARTTTRDSQFPLAQLPAQWQIPWGSVRTDIGRVELTLYLPSPHQNILKLPHHHGDFSYRPKFQPVPTSVISATSMTLL", "length": 82, "header": "tr|A0A8V0Z352-1|A0A8V0Z352_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z352-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z352-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z352/entry#A0A8V0Z352-1", "sequence": { "sequence": "MSVIARTTTRDSQFPLAQLPAQWQIPWGSVRTDIGRVELTLYLPSPHQNILKLPHHHGDFSYRPKFQPVPTSVISATSMTLL", "length": 82, "header": "tr|A0A8V0Z352-1|A0A8V0Z352_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z352-1" }, "locus": { "chromosome": "3", "start_pos": 10870136, "end_pos": 10869446, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042850.1", "url": "https://www.ensembl.org/id/ENSGALT00010042850.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025340.1", "url": "https://www.ensembl.org/id/ENSGALP00010025340.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z362-1", "uniprot_ac": "A0A8V0Z362", "uniprot_id": "A0A8V0Z362_CHICK", "mass": { "chemical_mass": 165990.0, "monoisotopic_mass": 165990.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "IgGFc-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z362", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z362/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z362", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z362" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z362", "locus": {} } ], "crossref": [ { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339:SF374", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339:SF374", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z362", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z362", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z362-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z362-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA48", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZA48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDDFTAFPFVLAAITCPANSHYEPCAAACPATCVNPMAPVTCGLPCVEGCVCDSGYLLYNSQCVPSQQCGCWHNGQHYPVGSEFWTDNTCSSKCTCPTRGGKVQCSSASCPAGQFCGVQNGKPECLEHSYGICHVHGDPHYNTFDKVTHNFMGNCTYTLAKVCSNTSVPYFNVEAKNEHRGNPRVSYVREVVVDVYGERITILKQERSRVLVNGEYRTLPVSAAGGAITVSSSGRYVVLETDFSLHVSYDADHSVEVKVPSSYFNLTCGMCGNFNNRREDDYMMPNGQQAADSNALGESWQVPSSDSDPSCGVPPPTEPCPADKEKLYESEQFCGMLTARPGVFESCHAVINPQSYFETCSYDLCAMSGAQEVLCGALEAYADACQAAGVTLLPWRNATFCPLPCSANSYYDPCMTGCPATCVDREAPQNCSKPCMEGCACASGFLLSGDTCVPEARCGCLFEGNYYSEGESFVSENCSRRCRCEASGQMVCSALSCGEEEVCKVQNGQRGCFPASTAVCHIYGDPHYNTFDGKLHHFQGSCNYTVVTACDNSSLGFSITIRNEHRGNPSWTALNSINGALATLPASPTPNVNVSLSGSYVQVSTKLGLQLQFNGDQELLVRVSEKHKGKLCGLCGTYTGSKEDDFRRPDGVVVPDFNDFGASWMVPDDEGQAEVCSPEGNGDCGPPGGPFQPCHAVLPPQAYFESCVYDQCGTGGSTEQLCSDLSSYAEACAAAGVVLGDWSSGTVCGEESVYILFKSSPPAACNFSCTFDVDFCEWVQEPSSSIDWIRHKGPTPSPDTGPSFDHTTGGRNINQHTAVIQAERCPREDGDKCLLRADTRTCVVEGDPHYHTFDKQIHNFMGNCTYTLSKLCESNSSLPFFNVEAANEHRGGNTRVSYVQYVDVDVYGQRIRLGKGGVVLPCTPSVGVQVSSSGFYTMVTTDFGLRVKFDGNHRVEVTLPSTFGQKVCGMCGNYNGMAADDFLNPDGVSGEGSNFCGLLTDTSGPFEVCHAVLSASGYFDTCLYDLCELGLDREALCNSLQSYADACQALGVQIPVWRNATFCPITCPANSHYEPCAAACPATCVSPTAPYNCSLPCVEGCVCDSGYLLYNSQCVPSQQCGCWHNGQHYPVGSEFWTDNTCSSKCTCPMRGGKVQCSSASCPAGQFCGVQNGKPECLEHSYGICHVHGDPHYNTFDKVTHNFMGNCTYTLAKVCSNTSVPYFNVEAKNEHRGNPRVSYVREVVVDVYGERITILKQERSRVLVNGEYRTLPVSAAGGAITVSSSGRYVVLETDFSLHVSYDADHSVEVKVPSSYFNLTCGMCGNFNNRREDDYMMPNGQQAADSNALGESWQVPSSDSDPSCGVPPPTEPCPADKEKLYESEQFCGMLTARPGVFESCHAVINPQSYFETCSYDLCAMSGAQEVLCGALEAYADACQAAGVTLLPWRNATFCPLPCSANSYYDPCMTGCPATCVDREAPQNCSKPCMEGCACASGFLLSGDTCVPEARCGCLFEGNYYSVSENPALSPSPPMALLCISVCA", "length": 1542, "header": "tr|A0A8V0Z362-1|A0A8V0Z362_CHICK Isoform 1 of IgGFc-binding protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z362-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z362-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z362/entry#A0A8V0Z362-1", "sequence": { "sequence": "MTDDFTAFPFVLAAITCPANSHYEPCAAACPATCVNPMAPVTCGLPCVEGCVCDSGYLLYNSQCVPSQQCGCWHNGQHYPVGSEFWTDNTCSSKCTCPTRGGKVQCSSASCPAGQFCGVQNGKPECLEHSYGICHVHGDPHYNTFDKVTHNFMGNCTYTLAKVCSNTSVPYFNVEAKNEHRGNPRVSYVREVVVDVYGERITILKQERSRVLVNGEYRTLPVSAAGGAITVSSSGRYVVLETDFSLHVSYDADHSVEVKVPSSYFNLTCGMCGNFNNRREDDYMMPNGQQAADSNALGESWQVPSSDSDPSCGVPPPTEPCPADKEKLYESEQFCGMLTARPGVFESCHAVINPQSYFETCSYDLCAMSGAQEVLCGALEAYADACQAAGVTLLPWRNATFCPLPCSANSYYDPCMTGCPATCVDREAPQNCSKPCMEGCACASGFLLSGDTCVPEARCGCLFEGNYYSEGESFVSENCSRRCRCEASGQMVCSALSCGEEEVCKVQNGQRGCFPASTAVCHIYGDPHYNTFDGKLHHFQGSCNYTVVTACDNSSLGFSITIRNEHRGNPSWTALNSINGALATLPASPTPNVNVSLSGSYVQVSTKLGLQLQFNGDQELLVRVSEKHKGKLCGLCGTYTGSKEDDFRRPDGVVVPDFNDFGASWMVPDDEGQAEVCSPEGNGDCGPPGGPFQPCHAVLPPQAYFESCVYDQCGTGGSTEQLCSDLSSYAEACAAAGVVLGDWSSGTVCGEESVYILFKSSPPAACNFSCTFDVDFCEWVQEPSSSIDWIRHKGPTPSPDTGPSFDHTTGGRNINQHTAVIQAERCPREDGDKCLLRADTRTCVVEGDPHYHTFDKQIHNFMGNCTYTLSKLCESNSSLPFFNVEAANEHRGGNTRVSYVQYVDVDVYGQRIRLGKGGVVLPCTPSVGVQVSSSGFYTMVTTDFGLRVKFDGNHRVEVTLPSTFGQKVCGMCGNYNGMAADDFLNPDGVSGEGSNFCGLLTDTSGPFEVCHAVLSASGYFDTCLYDLCELGLDREALCNSLQSYADACQALGVQIPVWRNATFCPITCPANSHYEPCAAACPATCVSPTAPYNCSLPCVEGCVCDSGYLLYNSQCVPSQQCGCWHNGQHYPVGSEFWTDNTCSSKCTCPMRGGKVQCSSASCPAGQFCGVQNGKPECLEHSYGICHVHGDPHYNTFDKVTHNFMGNCTYTLAKVCSNTSVPYFNVEAKNEHRGNPRVSYVREVVVDVYGERITILKQERSRVLVNGEYRTLPVSAAGGAITVSSSGRYVVLETDFSLHVSYDADHSVEVKVPSSYFNLTCGMCGNFNNRREDDYMMPNGQQAADSNALGESWQVPSSDSDPSCGVPPPTEPCPADKEKLYESEQFCGMLTARPGVFESCHAVINPQSYFETCSYDLCAMSGAQEVLCGALEAYADACQAAGVTLLPWRNATFCPLPCSANSYYDPCMTGCPATCVDREAPQNCSKPCMEGCACASGFLLSGDTCVPEARCGCLFEGNYYSVSENPALSPSPPMALLCISVCA", "length": 1542, "header": "tr|A0A8V0Z362-1|A0A8V0Z362_CHICK Isoform 1 of IgGFc-binding protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z362-1" }, "locus": { "chromosome": "9", "start_pos": 12882931, "end_pos": 12873933, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042860.1", "url": "https://www.ensembl.org/id/ENSGALT00010042860.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025350.1", "url": "https://www.ensembl.org/id/ENSGALP00010025350.1" } ] } }, { "isoform_ac": "A0A8V0ZA48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z362/entry#A0A8V0ZA48-1", "sequence": { "sequence": 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"length": 1542, "header": "tr|A0A8V0ZA48-1|A0A8V0Z362_CHICK Computationally mapped isoform of IgGFc-binding protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z362-1" }, "locus": { "chromosome": "9", "start_pos": 12875712, "end_pos": 12866714, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042852.1", "url": "https://www.ensembl.org/id/ENSGALT00010042852.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025342.1", "url": "https://www.ensembl.org/id/ENSGALP00010025342.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1089, "start_aa": "Thr", "end_pos": 1089, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1089", "evidence": [ { "id": 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NFU1 iron-sulfur cluster scaffold homolog, mitochondrial OS=Gallus gallus OX=9031 GN=NFU1 PE=1 SV=1 CANONICAL=A0A8V0Z363-1" }, "locus": { "chromosome": "22", "start_pos": 160189, "end_pos": 149000, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042412.1", "url": "https://www.ensembl.org/id/ENSGALT00010042412.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024901.1", "url": "https://www.ensembl.org/id/ENSGALP00010024901.1" } ] } }, { "isoform_ac": "A0A8V0Z903-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z363/entry#A0A8V0Z903-1", "sequence": { "sequence": "MAAGRMICHTMLKGHNLTTQQPFHQLARRKQLLPSAVLHNTVRCMFIQTQDTPNPNSLKFIPGKEVLESRTMEFSSPAAAFCSPLARQLFRIEGVKSVFFGPDFITITKESEDLDWNLLKPDIYATIMDFFASGLPVLTEEAPRTDTAQSEEDDEVVLMIKELLDTRIRPTVQEDGGDVIYKGFEDGIVQLKLQGSCTSCPSSIITLKNGIQNMLQFYIPEVEGVEQVVDDDDDVEKEANST", "length": 242, "header": "tr|A0A8V0Z903-1|A0A8V0Z363_CHICK Computationally mapped isoform of NFU1 iron-sulfur cluster scaffold homolog, mitochondrial OS=Gallus gallus OX=9031 GN=NFU1 PE=1 SV=1 CANONICAL=A0A8V0Z363-1" }, "locus": { "chromosome": "22", "start_pos": 160189, "end_pos": 149187, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042419.1", "url": "https://www.ensembl.org/id/ENSGALT00010042419.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010024909.1", "url": "https://www.ensembl.org/id/ENSGALP00010024909.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9857492", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9857492", "resource": "Reactome", "description": "Protein lipoylation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "iron-sulfur cluster assembly", "id": "GO:0016226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z363", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z363" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z363", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z363" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z363", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z363" } ], "pmid": "" }, { "name": "4 iron, 4 sulfur cluster binding", "id": "GO:0051539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z363", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z363" } ], "pmid": "" }, { "name": "2 iron, 2 sulfur cluster binding", "id": "GO:0051537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051537", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z363", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z363" } ], "pmid": "" }, { "name": "iron-sulfur cluster binding", "id": "GO:0051536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051536", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z363", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z363" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z363", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z363" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z363", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z363" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z363", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z363" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z363", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z363" }, { "id": "SM00932", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00932" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Scaffold protein Nfu/NifU N-terminal", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 178, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 284, "end_pos": 286 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4C1-1", "uniprot_ac": "A0A8V0Z4C1", "uniprot_id": "A0A8V0Z4C1_CHICK", "mass": { "chemical_mass": 57553.0, "monoisotopic_mass": 57553.0 }, "refseq": { "ac": "XP_046757002", "name": "mitochondrial dynamics protein MID49 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757002" }, "gene_names": [ { "name": "MIEF2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C1" } ] }, { "name": "MIEF2", "type": "synonym", "evidence": [ { "id": "XP_046757002", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757002" } ] } ], "protein_names": [ { "name": "Mitochondrial elongation factor 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C1/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial dynamics protein MID49 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_046757002", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757002" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_046757002", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757002" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MIEF2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C1", "locus": { "chromosome": "14", "start_pos": 5087621, "end_pos": 5083085, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017729", "url": "https://www.ensembl.org/id/ENSGALG00010017729" } ] } } ], "crossref": [ { "id": "A0A8V0Z4C1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4C1", "database": "AlphaFoldDB", "categories": [] }, { "id": "416516", "url": "https://www.ncbi.nlm.nih.gov/gene/416516", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416516", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416516", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDRHLVG", "url": "https://omabrowser.org/oma/group/WDRHLVG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z367", "url": "https://www.orthodb.org/?gene=A0A8V0Z367", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4C1", "url": "https://www.orthodb.org/?gene=A0A8V0Z4C1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16451", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16451", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16451:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16451:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_046757002", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_046757002", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z367", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z367", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z367-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z367-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYAGLYPEYRCGPLVPSPSAGAEYWRGLRNGGARRPEPYRGDPWSGPAPPPQPVAAGALGLKVTMAEFTQQSGKRRDDGGLGSVLDLLLANARLVLGVSGAAVLAIATLAVKRLIDRATSPREEDDPKAEQKSLEESWQDLALIKATQKPPKKQRREDLSEPLLSPAPPPAPEPRACPVPPEPPQVESSPPSCLTLQEKLLSHYSIHLPMSEEQVAVAQQLAQSICAELQSFMRSKCPELPFGSLFLSGPLLDGLGALAADHIHFMLPVVLDATLWSLIPGEDTVVRNPRYWLIKRTDLEYFPRGRSPWDRFLVGQYLSSNVLNETLHKMLVASINWPAIGSLLGTVIRPLVASRELRLDVKHDQVELSIALFPVVEMEDKVLLAAPPEGLVENLWLESFGRAEVLKVKELDAGDAGTRQHCLCILNGVCRSHPTLRRLSGSPLAHVILHLSTAESDWAEESLATRFQQVLEELVGYLENGVLPCYFNPKVNLFCELVEEEIEEMGFLLYRAVSEPGLLLTEK", "length": 523, "header": "tr|A0A8V0Z4C1-1|A0A8V0Z4C1_CHICK Isoform 1 of Mitochondrial elongation factor 2 OS=Gallus gallus OX=9031 GN=MIEF2 PE=4 SV=1 CANONICAL=A0A8V0Z4C1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z367-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C1/entry#A0A8V0Z367-1", "sequence": { "sequence": "MAEFTQQSGKRRDDGGLGSVLDLLLANARLVLGVSGAAVLAIATLAVKRLIDRATSPREEDDPKAEQKSLEESWQDLALIKATQKPPKKQRREDLSEPLLSPAPPPAPEPRACPVPPEPPQVESSPPSCLTLQEKLLSHYSIHLPMSEEQVAVAQQLAQSICAELQSFMRSKCPELPFGSLFLSGPLLDGLGALAADHIHFMLPVVLDATLWSLIPGEDTVVRNPRYWLIKRTDLEYFPRGRSPWDRFLVGQYLSSNVLNETLHKMLVASINWPAIGSLLGTVIRPLVASRELRLDVKHDQVELSIALFPVVEMEDKVLLAAPPEGLVENLWLESFGRAEVLKVKELDAGDAGTRQHCLCILNGVCRSHPTLRRLSGSPLAHVILHLSTAESDWAEESLATRFQQVLEELVGYLENGVLPCYFNPKVNLFCELVEEEIEEMGFLLYRAVSEPGLLLTEK", "length": 459, "header": "tr|A0A8V0Z367-1|A0A8V0Z4C1_CHICK Computationally mapped isoform of Mitochondrial elongation factor 2 OS=Gallus gallus OX=9031 GN=MIEF2 PE=4 SV=1 CANONICAL=A0A8V0Z4C1-1" }, "locus": { "chromosome": "14", "start_pos": 5086333, "end_pos": 5083678, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042865.1", "url": "https://www.ensembl.org/id/ENSGALT00010042865.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025355.1", "url": "https://www.ensembl.org/id/ENSGALP00010025355.1" } ] } }, { "isoform_ac": "A0A8V0Z4C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C1/entry#A0A8V0Z4C1-1", "sequence": { "sequence": "MYAGLYPEYRCGPLVPSPSAGAEYWRGLRNGGARRPEPYRGDPWSGPAPPPQPVAAGALGLKVTMAEFTQQSGKRRDDGGLGSVLDLLLANARLVLGVSGAAVLAIATLAVKRLIDRATSPREEDDPKAEQKSLEESWQDLALIKATQKPPKKQRREDLSEPLLSPAPPPAPEPRACPVPPEPPQVESSPPSCLTLQEKLLSHYSIHLPMSEEQVAVAQQLAQSICAELQSFMRSKCPELPFGSLFLSGPLLDGLGALAADHIHFMLPVVLDATLWSLIPGEDTVVRNPRYWLIKRTDLEYFPRGRSPWDRFLVGQYLSSNVLNETLHKMLVASINWPAIGSLLGTVIRPLVASRELRLDVKHDQVELSIALFPVVEMEDKVLLAAPPEGLVENLWLESFGRAEVLKVKELDAGDAGTRQHCLCILNGVCRSHPTLRRLSGSPLAHVILHLSTAESDWAEESLATRFQQVLEELVGYLENGVLPCYFNPKVNLFCELVEEEIEEMGFLLYRAVSEPGLLLTEK", "length": 523, "header": "tr|A0A8V0Z4C1-1|A0A8V0Z4C1_CHICK Isoform 1 of Mitochondrial elongation factor 2 OS=Gallus gallus OX=9031 GN=MIEF2 PE=4 SV=1 CANONICAL=A0A8V0Z4C1-1" }, "locus": { "chromosome": "14", "start_pos": 5086333, "end_pos": 5083340, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042864.1", "url": "https://www.ensembl.org/id/ENSGALT00010042864.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025354.1", "url": "https://www.ensembl.org/id/ENSGALP00010025354.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416516", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416516", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitochondrion organization", "id": "GO:0007005", "url": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3B3-1", "uniprot_ac": "A0A8V0Z3B3", "uniprot_id": "A0A8V0Z3B3_CHICK", "mass": { "chemical_mass": 54419.0, "monoisotopic_mass": 54419.0 }, "refseq": { "ac": "XP_040503650", "name": "zinc finger protein GLIS2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503650" }, "gene_names": [ { "name": "GLIS2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3" } ] }, { "name": "GLIS2", "type": "synonym", "evidence": [ { "id": "XP_040503650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503650" } ] } ], "protein_names": [ { "name": "Zinc finger protein GLIS2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3/entry#names_and_taxonomy" } ] }, { "name": "GLI-similar 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3/entry#names_and_taxonomy" } ] }, { "name": "Neuronal Krueppel-like protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein GLIS2", "type": "synonym", "evidence": [ { "id": "XP_040503650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503650" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040503650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503650" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GLIS2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3", "locus": { "chromosome": "14", "start_pos": 12701637, "end_pos": 12697151, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016562", "url": "https://www.ensembl.org/id/ENSGALG00010016562" } ] } } ], "crossref": [ { "id": "A0A8V0Z3B3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3B3", "database": "AlphaFoldDB", "categories": [] }, { "id": "374023", "url": "https://www.ncbi.nlm.nih.gov/gene/374023", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EAGYCCH", "url": "https://omabrowser.org/oma/group/EAGYCCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3B3", "url": "https://www.orthodb.org/?gene=A0A8V0Z3B3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45718:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45718:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040503650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503650", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHSLDEPLDLKLSISKVRSAREKRERGPPGPRPRAVPPSAAAPPPVGESRGSARGGRRAGPGPGLLAHSKALEKRFPALPVMDLSLSPPPGVESPGGGSASLSPERHSDPPVPALPHDFQSLRYIDGIPGSFQFFLPLGAGGALHLPSFLPPPKDKRLSPELPLPKQLVCRWSKCNQFFDLLQDLVDHVNDFHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYICPYEGCNKRYSNSSDRFKHTRTHYVEKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEHHEMLKAHAPPKGSADAPYANGAQLLLPNPAALFAPHALPALPLPLAPAPLDLSALGCGAGGSLPALPGPALPLNGGGPLNLAKGPLLPSPFAAGGLGLPVMSLLAGGAKAEEAEGRKGGKEGRKAGGRRTEPGRLRAPPESLALLPGAVLDLSTGVGAAGSPPEALPPGWVVIPPGSLLLKPAVVN", "length": 511, "header": "tr|A0A8V0Z3B3-1|A0A8V0Z3B3_CHICK Isoform 1 of Zinc finger protein GLIS2 OS=Gallus gallus OX=9031 GN=GLIS2 PE=3 SV=1 CANONICAL=A0A8V0Z3B3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3/entry#A0A8V0Z3B3-1", "sequence": { "sequence": "MHSLDEPLDLKLSISKVRSAREKRERGPPGPRPRAVPPSAAAPPPVGESRGSARGGRRAGPGPGLLAHSKALEKRFPALPVMDLSLSPPPGVESPGGGSASLSPERHSDPPVPALPHDFQSLRYIDGIPGSFQFFLPLGAGGALHLPSFLPPPKDKRLSPELPLPKQLVCRWSKCNQFFDLLQDLVDHVNDFHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYICPYEGCNKRYSNSSDRFKHTRTHYVEKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEHHEMLKAHAPPKGSADAPYANGAQLLLPNPAALFAPHALPALPLPLAPAPLDLSALGCGAGGSLPALPGPALPLNGGGPLNLAKGPLLPSPFAAGGLGLPVMSLLAGGAKAEEAEGRKGGKEGRKAGGRRTEPGRLRAPPESLALLPGAVLDLSTGVGAAGSPPEALPPGWVVIPPGSLLLKPAVVN", "length": 511, "header": "tr|A0A8V0Z3B3-1|A0A8V0Z3B3_CHICK Isoform 1 of Zinc finger protein GLIS2 OS=Gallus gallus OX=9031 GN=GLIS2 PE=3 SV=1 CANONICAL=A0A8V0Z3B3-1" }, "locus": { "chromosome": "14", "start_pos": 12700633, "end_pos": 12698558, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039889.1", "url": "https://www.ensembl.org/id/ENSGALT00010039889.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023090.1", "url": "https://www.ensembl.org/id/ENSGALP00010023090.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QHY8-1", "protein_name": "Zinc finger protein GLIS2", "gene_name": "GLIS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHSLDEPLDLKLSITKLRAAREKRERTLSAVRHRALHRELGLVDDSPTPGSPGSPPSGFLLNPKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLSAVPTGPDLQPLRYLDGVPSSFQFLLPLGSGGALHLPASSFLPPPKDKCLSPELPLPKQLVCRWAKCNQPFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGSPYVSGAQIIIPNPAALFGGPGLPGLPLPLAPGPLDLSALACGNGGGGGGAGGMGPGLPGPVLPLNLAKSPLLPSPFGAGGLGLPVVSLLAGSAGGKAEGEKGRGAMPARALGMEGRKTPLERTESSRSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN", "length": 524 }, "evidence": [ { "id": "A0A8V0Z3B3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3B3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZIA9-1", "protein_name": "Zinc finger protein GLIS2", "gene_name": "Glis2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHSLDEPLDLKLSITKLRAAREKRERTLGVPRHHALHRELGLVDDSPTPGSPGSPPPGFLLNPKFPEKLDGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPLPTAVDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPELPLAKQLVCRWAKCNQLFELLQDLVDHVNDHHVKPEQDARYCCHWEGCARHGRGFNASRYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPTPDSGSYVSGAQIIIPNPAALFGGPSLPGLPLPLAPGPLDLSALACGNGGGGGGGMGPGLPGSVLPLNLAKNPLLPSPFGAGGLGLPVVSLLGGSAGSKAEGEKGRGSVPARVLGLEDHKTSLERTERSRSRPSPDGLPLLPGTVLDLSTGNSAASSPEALTPGWVVIPPGSVLLKPAVVN", "length": 522 }, "evidence": [ { "id": "A0A8V0Z3B3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3B3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BKE4-1", "protein_name": "Zinc finger protein GLIS2", "gene_name": "GLIS2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHSLDEPLDLKLSITKLRAAREKRERTLSAARHRALHRELGLADDSPTPGSPGSPPSGFLLNPKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPTAPAGPDLQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPELPLPKQLVCRWAKCNQPFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQHELLQLRPPPKPPLPAPDGSPYVSGAQIIIPNPAALFGGPGLPGLPLPLAPGPLDLSALACGNGGGAGGAGGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGSAGGKAEGEKGRGAMPARALSSEGRKTPLERTEGSRSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN", "length": 524 }, "evidence": [ { "id": "A0A8V0Z3B3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3B3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8VDL9-1", "protein_name": "Zinc finger protein GLIS2", "gene_name": "Glis2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHSLDEPLDLKLSITKLRAAREKRERTLGVVRHHALHRELGLVDDSPAPGSPGSPPPGFLLNPKFPEKVDGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPECQGNGDLPPLPTAVDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLPPPKDKCLSPELPLAKQLVCRWAKCNQLFELLQDLVDHVNDHHVKPEQDARYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPTPDSGSYVSGAQIIIPNPAALFGGPSLPGLPLPLPPGPLDLSALACGNGGGGGGGIGPGLPGSVLPLNLAKNPLLPSPFGAGGLGLPVVSLLGGSAGSKAEGEKGRGSVPARVLGLEDHKTPLERTERSRSRPSPDGLPLLPGTVLDLSTGNSAASSPEVLTPGWVVIPPGSVLLKPAVVN", "length": 521 }, "evidence": [ { "id": "A0A8V0Z3B3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3B3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZE0-1", "protein_name": "Zinc finger protein GLIS2", "gene_name": "GLIS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHSLDEPLDLKLSITKLRAAREKRERTLGVVRPRALHRELGLVDDSPTPGSPGSPPSGFLLNSKFPEKVEGRFSAAPLVDLSLSPPSGLDSPNGSSSLSPERQGNGDLPPVPSASDFQPLRYLDGVPSSFQFFLPLGSGGALHLPASSFLTPPKDKCLSPDLPLPKQLVCRWAKCNQLFELLQDLVDHVNDYHVKPEKDAGYCCHWEGCARHGRGFNARYKMLIHIRTHTNEKPHRCPTCSKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFKHTRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIKAHGHFVSHEQQELLQLRPPPKPPLPAPDGGPYVSGAQIIIPNPAALFGGPGLPGLPLPLAPGPLDLSALACGNGGGSGGGGGMGPGLPGPVLPLNLAKNPLLPSPFGAGGLGLPVVSLLAGAAGGKAEGEKGRGSVPTRALGMEGHKTPLERTESSCSRPSPDGLPLLPGTVLDLSTGVNSAASSPEALAPGWVVIPPGSVLLKPAVVN", "length": 524 }, "evidence": [ { "id": "A0A8V0Z3B3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3B3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B3", "url": 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"id": "A0A8V0Z3B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3B3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3B3" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3D6-1", "uniprot_ac": "A0A8V0Z3D6", "uniprot_id": "A0A8V0Z3D6_CHICK", "mass": { "chemical_mass": 84864.0, "monoisotopic_mass": 84864.0 }, "refseq": { "ac": "XP_413904", "name": "immunoglobulin superfamily DCC subclass member 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_413904" }, "gene_names": [ { "name": "IGDCC3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6" } ] }, { "name": "IGDCC3", "type": "synonym", "evidence": [ { "id": "XP_413904", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_413904" } ] } ], "protein_names": [ { "name": "Immunoglobulin superfamily DCC subclass member 3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6/entry#names_and_taxonomy" } ] }, { "name": "Putative neuronal cell adhesion molecule", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6/entry#names_and_taxonomy" } ] }, { "name": "immunoglobulin superfamily DCC subclass member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_413904", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_413904" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_413904.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_413904", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_413904" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IGDCC3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6", "locus": { "chromosome": "10", "start_pos": 17868495, "end_pos": 17952357, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017764", "url": "https://www.ensembl.org/id/ENSGALG00010017764" } ] } } ], "crossref": [ { "id": "A0A8V0Z3D6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3D6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_413904", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_413904", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRGSALPACLLGLLLLLGCCGDFGHSSELAFVVEPSDDIAVQEQPLILYCQVEGIQPITITWRKNGAMIVDSENAFMLANGSLYVSRFQRVRGDGSSDEGEYDCMAQNHYGLVVSRKAKIQAATMSDFHIHPQNAVVEEGGVARFQCQIHGLPEPVILWQKNRMPVNTDNERYTLLPKGVLQITGLRAEDSGIFHCVATNIANVKFSREARLTVSGSHSTVYKDPMILVGPENLTLTVHQTAVLECIATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLMISDLSVQHSGIYVCAANKPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPVGTTAIFTCVAQGEPPPQITWLRNGQILETSDHIKLKNNNSTLSIYGINQADEAIYQCIAENSAGSTQASARLTVLWAEGLPGPPQSVRAETVSATTIQVSWEEPLQNTKEIIGYVLHIRKAADPVEMEYQEAVSKSTFQQLVTDLEPSTSYSFYIKAYTSRGASKASEVTVVSTLGEVPAMPSLFIKVINSTAVQATWEPSIKLGQHEGFKLYYRKVHLSQYTGPVLLASNVTAYNITHLDASMVYEVKLLAYNQHGDGNSTVRFVSLRETVERTVLNPPCDCMKDEQNNKTSATGIIIGIHIGVTCIIFCVLFLMFGYRGRLLMCKNVQEQLSTPQIPRSQRSAAGIILNGAARRDRDERDLNGKQLDMNELERLFPASPCPEQQDKGITPAHSPPAAHDNTQISTLPMDEFSIVEEQPDSPPKSPHDGSPTAPAPHHSPANEG", "length": 777, "header": "tr|A0A8V0Z3D6-1|A0A8V0Z3D6_CHICK Isoform 1 of Immunoglobulin superfamily DCC subclass member 3 OS=Gallus gallus OX=9031 GN=IGDCC3 PE=3 SV=1 CANONICAL=A0A8V0Z3D6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6/entry#A0A8V0Z3D6-1", "sequence": { "sequence": "MAPRGSALPACLLGLLLLLGCCGDFGHSSELAFVVEPSDDIAVQEQPLILYCQVEGIQPITITWRKNGAMIVDSENAFMLANGSLYVSRFQRVRGDGSSDEGEYDCMAQNHYGLVVSRKAKIQAATMSDFHIHPQNAVVEEGGVARFQCQIHGLPEPVILWQKNRMPVNTDNERYTLLPKGVLQITGLRAEDSGIFHCVATNIANVKFSREARLTVSGSHSTVYKDPMILVGPENLTLTVHQTAVLECIATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLMISDLSVQHSGIYVCAANKPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPVGTTAIFTCVAQGEPPPQITWLRNGQILETSDHIKLKNNNSTLSIYGINQADEAIYQCIAENSAGSTQASARLTVLWAEGLPGPPQSVRAETVSATTIQVSWEEPLQNTKEIIGYVLHIRKAADPVEMEYQEAVSKSTFQQLVTDLEPSTSYSFYIKAYTSRGASKASEVTVVSTLGEVPAMPSLFIKVINSTAVQATWEPSIKLGQHEGFKLYYRKVHLSQYTGPVLLASNVTAYNITHLDASMVYEVKLLAYNQHGDGNSTVRFVSLRETVERTVLNPPCDCMKDEQNNKTSATGIIIGIHIGVTCIIFCVLFLMFGYRGRLLMCKNVQEQLSTPQIPRSQRSAAGIILNGAARRDRDERDLNGKQLDMNELERLFPASPCPEQQDKGITPAHSPPAAHDNTQISTLPMDEFSIVEEQPDSPPKSPHDGSPTAPAPHHSPANEG", "length": 777, "header": "tr|A0A8V0Z3D6-1|A0A8V0Z3D6_CHICK Isoform 1 of Immunoglobulin superfamily DCC subclass member 3 OS=Gallus gallus OX=9031 GN=IGDCC3 PE=3 SV=1 CANONICAL=A0A8V0Z3D6-1" }, "locus": { "chromosome": "10", "start_pos": 17952129, "end_pos": 17869076, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042925.1", "url": "https://www.ensembl.org/id/ENSGALT00010042925.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025415.1", "url": "https://www.ensembl.org/id/ENSGALP00010025415.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:415535", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415535", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQ86-1", "protein_name": "Immunoglobulin superfamily DCC subclass member 3", "gene_name": "Igdcc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEPRTASPRRPPALRRPRLLPPLLPPLLPPLLLLLLPLPVPSLGLGHSAELAFSVEPNDDIANLGQPIMLGCKVEGSPPVQVSWRKNGAELPEDTHTTLLANGSLLIHHLRLEQGESPSDEGDYECVAQNRFGLLVSRKARIQVATMSDFHVHPQAVMGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDDERYTLLPKGVLQITGLRAEDSGVFHCVASNMASVRVSHGARLTVSGSGSGTYKEPTILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGAGGHVRLKNNNSTLSISGVGPEDEAIYQCVAENIAGSSQASARLTVLWAEGLPGPPRNVRAVSVSSTEVRVSWSEPLTHTKEIIGYVLHIRKAADSPKLEYQEAVSKSTFQHLVRDLEPSTAYSFYIKAYTPRGASLASVPTLASTLGEAPVPPPLSVRLLGSSSLQLLWKPWPRLAQHNGGFKLFYRPASAASFTGPILLPGTVSSYNLSQLDPSTVYEVKLLAYNQNGDGNATVRFVSLKGASERTALTPPCDCRKEEVTNHTSTTGIVIGIHIGVTCIIFCVLFLLFGQRGRVLLCKDVENQLSPPQGPRSQRDPGILTLNGVNRGEGGQLGRDEKHVDAKELEQLFPTTASAGQPGSRSTDPTAPTPYEETQLSMVQLQDFNLAAGRTTETMSSCAGPGPVPASQDVGLGLLSDRQTAQPLAVPAPQ", "length": 812 }, "evidence": [ { "id": "A0A8V0Z3D6", "url": "https://omabrowser.org/oma/group/A0A8V0Z3D6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BQC3-1", "protein_name": "Immunoglobulin superfamily DCC subclass member 3", "gene_name": "Igdcc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPRTASPRRLPALRRPGFLPPLLPPPPPPLLLLLLLLPLPAPSLGLGHSAELAFSVEPNDDIANPGQPIVLGCKVEGTPPVQVSWRKNGAELPEGTHTTLLANGSLLIHHFRLEQGGSPSDEGDYECVAQNRFGLLVSRKARLQAATMSDFHVHPQAVTGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDDERYTLLPKGVLQITGLRAEDSGIFHCVASNIASVRVSHGARLTVSGSGSGTYKEPTILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGAGGHVRLKNNNSTLSISGVGPEDEAIYQCVAENIAGSSQASARLTVLWAEGLPGPPRNVRAVSVSSTEVRVSWSEPLAHTKEIIGYVLHIRKAADSPKLEYQEAVSKSTFQHLVRDLEPSTAYSFYIKAYTPRGASLASVPTLASTLGEAPVPPPLSVRLLGSSSLQLLWKPWPRLAQHNGGFKLFYRPVSATSFTGPILLPGTVSSYNLSQLDPSTVYEVKLLAYNQHGDGNATVRFVSLKGASERTALTPPCDCRKEDVTNHTSTTGIVIGIHIGVTCIIFCVLFLLFGQRGRVLLCKDVENQLSPPQGPRSQRDPGILALNGLSRGEGGQLSRDEKPVDAKELEQLFPTAGSAAQPGSTPTDPAAPAPCEETQLSMVQLQGFNLVAGRTTEATSPCAGPGPVPAPQDIGPVPLSEGQTQPPAVAAPQ", "length": 813 }, "evidence": [ { "id": "A0A8V0Z3D6", "url": "https://omabrowser.org/oma/group/A0A8V0Z3D6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IVU1-1", "protein_name": "Immunoglobulin superfamily DCC subclass member 3", "gene_name": "IGDCC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVQRAASPRRPPAPLWPRLLLPLLLLLLPAPSEGLGHSAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPRNVRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRKAADPPELEYQEAVSKSTFQHLVSDLEPSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPPLSVRVLGSSSLQLLWEPWPRLAQHEGGFKLFYRPASKTSFTGPILLPGTVSSYNLSQLDPTAVYEVKLLAYNQHGDGNATVRFVSLRGASERTALSPPCDCRKEEAANQTSTTGIVIGIHIGVTCIIFCVLFLLFGQRGRVLLCKDVENQLSPPQGPRSQRDPGILALNGARRGQRGQLGRDEKRVDMKELEQLFPPASAAGQPDPRPTQDPAAPAPCEETQLSVLPLQGCGLMEGKTTEAKTTEATAPCAGLAAAPPPPDGGPGLLSEGQASRPAAARVTQPAHSEQ", "length": 814 }, "evidence": [ { "id": "A0A8V0Z3D6", "url": "https://omabrowser.org/oma/group/A0A8V0Z3D6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VM64-1", "protein_name": "Interference hedgehog", "gene_name": "ihog", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTLLTSSLLLFSLLTSRLEAIPVLEKSPAHPAHSAHPAHPAHPAHPAHPSPGVRILRAPESLVAPLGDEVVLECETSLQPERFEWSHRSSRSPGAGFKYLKTGTAKANVSQEAAISRLRVLVRPDTLGEYRCVGWFGPLVVTSTIARLELASTSLVDAQESESPLQWRVSAGNSVLWSCGQQVQSNPSASWSYYRNGVEIKPEFIGTNGNLFLSNVSSESSGSYSCQATNPASGERIQLPGSLQLQVTPEQRSESKSPHLLRGQPSSQEITIREGSSLLLLCPGVGSPPPTVVWSSPDVVGAVKNKRSKVFGHALEISNTRVNDAGTYICFQDNGVRPALEHYIKVHVEQPPQIVRPPWADLTNEGDRLKLECKATGVPTPEIYWLLNGHSSIDDSEAELSNNFLILHSVLKRHAGYVQCFARNRLGEHSAGTLLQVNPKQIQEPRESGGTHRPKPNQGSRQKQMYPPTPPNVTRLSDESVMLRWMVPRNDGLPIVIFKVQYRMVGKRKNWQTTNDNIPYGKPKWNSELGKSFTASVTDLKPQHTYRFRILAVYSNNDNKESNTSAKFYLQPGAALDPMPVPELLEIEEYSETAVVLHWSLASDADEHLITGYYAYYRPSSSAGEYFKATIEGAHARSFKIAPLETATMYEFKLQSFSAASASEFSALKQGRTQRPKTSTTEEPTLQMGDRDTTTPSHNETFNMSPMLTGTIGGGAVLILLLISTCFCVCRRRNSRSRGNNPNKPRMAELRDDFVPLGNCSPTKQRQRTRHIHITLNPLAQQQQQALEEKNDTDQDAPYYQRPSSYDYDPTLRRMSSSSLRRSQRTLERAGGSNGSNNGNNNNLNQSAEAGSIENPGKPGRVLMKRPRLSSRSENLSSGSLNSVGV", "length": 886 }, "evidence": [ { "id": "A0A8V0Z3D6", "url": "https://omabrowser.org/oma/group/A0A8V0Z3D6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 415, "end_pos": 509, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z3D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3D6" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 123, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 235, "end_pos": 237 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 371, "end_pos": 373 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 563, "end_pos": 565 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 592, "end_pos": 594 }, { "start_pos": 622, "end_pos": 624 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3E1-1", "uniprot_ac": "A0A8V0Z3E1", "uniprot_id": "A0A8V0Z3E1_CHICK", "mass": { "chemical_mass": 68199.0, "monoisotopic_mass": 68199.0 }, "refseq": {}, "gene_names": [ { "name": "SYT16", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1" } ] } ], "protein_names": [ { "name": "Synaptotagmin 16", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I6#function" }, { "database": "UniProtKB", "id": "ARBA00056709", "url": "https://www.uniprot.org/uniprotkb/ARBA00056709#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SYT16", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1", "locus": { "chromosome": "5", "start_pos": 53354940, "end_pos": 53465764, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017765", "url": "https://www.ensembl.org/id/ENSGALG00010017765" } ] } } ], "crossref": [ { "id": "A0A8V0Z3E1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3E1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08389", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08389", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08408", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08408", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423516", "url": "https://www.ncbi.nlm.nih.gov/gene/423516", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CAIRFRL", "url": "https://omabrowser.org/oma/group/CAIRFRL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3E1", "url": "https://www.orthodb.org/?gene=A0A8V0Z3E1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4I2", "url": "https://www.orthodb.org/?gene=A0A8V0Z4I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4I6", "url": "https://www.orthodb.org/?gene=A0A8V0Z4I6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46129:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46129:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z3E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSEAAQSFLQPLSSWLSQIYEAIQQAGDSISASLLNLNGVGRESEEDRNRGLEGNGVAYEDYSVESEDERHIDLWDEEYICPREDGHIAGRDLASEALPCGSDMGMQRQKWVKNTTSLAGQCVERTGHLVANGSHWINEDLQPLPTISEDESEPSVRMRGHDHSISMDGSLEINKDKASFADLDGLSQLSYQDNLSCHEDDHVSVDSRTTERRSAGQHTGPRMESSIADGFSQQATEGRLELEAAFTNQGFEGNDATDSSSAWSPEETDEVNSEPAHHSAHQPICKCGDLDVIFSYKASSQKLVVTVLEARDIPDKDRSGVNTWQVHTVLMPSKKQRGKTSVQRGPIPMFKDNITFSKLEPHELGGHAVRFRLYAVHKVIGEKMMGEQLFYLSNVSQEEEVKVTLVLEPRSNLTSADSQLSLSAISHSDSASSTQSLSHGGVPELLVGLSYNATTGRLSVEMIKGSHFRNLAINRPPALPIPPWSIHSPAGTSPPSPPPRVAPVMGRASPSPSNAPSNAPSNRATSAPAGPIRAGHIWAPTSAGCSRAVMRSSVAAGTRRSCHQCHHLQRQPAARSGRERTKDGSSSPSRAGDRRVTFCGAVLPAMLAEPVRGDLTGTAGIIPERPFAD", "length": 630, "header": "tr|A0A8V0Z3E1-1|A0A8V0Z3E1_CHICK Isoform 1 of Synaptotagmin 16 OS=Gallus gallus OX=9031 GN=SYT16 PE=3 SV=1 CANONICAL=A0A8V0Z3E1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1/entry#A0A8V0Z3E1-1", "sequence": { "sequence": "MTSEAAQSFLQPLSSWLSQIYEAIQQAGDSISASLLNLNGVGRESEEDRNRGLEGNGVAYEDYSVESEDERHIDLWDEEYICPREDGHIAGRDLASEALPCGSDMGMQRQKWVKNTTSLAGQCVERTGHLVANGSHWINEDLQPLPTISEDESEPSVRMRGHDHSISMDGSLEINKDKASFADLDGLSQLSYQDNLSCHEDDHVSVDSRTTERRSAGQHTGPRMESSIADGFSQQATEGRLELEAAFTNQGFEGNDATDSSSAWSPEETDEVNSEPAHHSAHQPICKCGDLDVIFSYKASSQKLVVTVLEARDIPDKDRSGVNTWQVHTVLMPSKKQRGKTSVQRGPIPMFKDNITFSKLEPHELGGHAVRFRLYAVHKVIGEKMMGEQLFYLSNVSQEEEVKVTLVLEPRSNLTSADSQLSLSAISHSDSASSTQSLSHGGVPELLVGLSYNATTGRLSVEMIKGSHFRNLAINRPPALPIPPWSIHSPAGTSPPSPPPRVAPVMGRASPSPSNAPSNAPSNRATSAPAGPIRAGHIWAPTSAGCSRAVMRSSVAAGTRRSCHQCHHLQRQPAARSGRERTKDGSSSPSRAGDRRVTFCGAVLPAMLAEPVRGDLTGTAGIIPERPFAD", "length": 630, "header": "tr|A0A8V0Z3E1-1|A0A8V0Z3E1_CHICK Isoform 1 of Synaptotagmin 16 OS=Gallus gallus OX=9031 GN=SYT16 PE=3 SV=1 CANONICAL=A0A8V0Z3E1-1" }, "locus": { "chromosome": "5", "start_pos": 53406060, "end_pos": 53354957, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042930.1", "url": "https://www.ensembl.org/id/ENSGALT00010042930.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025420.1", "url": "https://www.ensembl.org/id/ENSGALP00010025420.1" } ] } }, { "isoform_ac": "A0A8V0Z4I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1/entry#A0A8V0Z4I2-1", "sequence": { "sequence": "METLGREQRGSHLHDFLCLSALLSYMPAAVSLFSFLPAHGIGLENVLKLYTYGKLCLLNSVGQEMSRCKTSIRRGQPNPVYKETFIFQVALFQLSDVTLMISIYNKRSMKRKEMIGWISMGQNSSGEEEQSHWQEMKESKGLQVCRWHTLLES", "length": 153, "header": "tr|A0A8V0Z4I2-1|A0A8V0Z4I2_CHICK Computationally mapped isoform of Synaptotagmin 16 OS=Gallus gallus OX=9031 GN=SYT16 PE=3 SV=1 CANONICAL=A0A8V0Z3E1-1" }, "locus": { "chromosome": "5", "start_pos": 53371188, "end_pos": 53368959, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042924.1", "url": "https://www.ensembl.org/id/ENSGALT00010042924.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025414.1", "url": "https://www.ensembl.org/id/ENSGALP00010025414.1" } ] } }, { "isoform_ac": "A0A8V0Z4I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1/entry#A0A8V0Z4I6-1", "sequence": { "sequence": "MTSEAAQSFLQPLSSWLSQIYEAIQQAGDSISASLLNLNGVGRESEEDRNRGLEGNGVAYEDYSVESEDERHIDLWDEEYICPREDGHIAGRDLASEALPCGSDMGMQRQKWVKNTTSLAGQCVERTGHLVANGSHWINEDLQPLPTISEDESEPSVRMRGHDHSISMDGSLEINKDKASFADLDGLSQLSYQDNLSCHEDDHVSVDSRTTERRSAGQHTGPRMESSIADGFSQQATEGRLELEAAFTNQGFEGNDATDSSSAWSPEETDEVNSEPAHHSAHQPICKCGDLDVIFSYKASSQKLVVTVLEARDIPDKDRSGVNTWQVHTVLMPSKKQRGKTSVQRGPIPMFKDNITFSKLEPHELGGHAVRFRLYAVHKVIGEKMMGEQLFYLSNVSQEEEVKVTLVLEPRSNLTSADSQLSLSAISHSDSASSTQSLSHGGVPELLVGLSYNATTGRLSVEMIKGSHFRNLAINRPPDTYGKLCLLNSVGQEMSRCKTSIRRGQPNPVYKETFIFQVALFQLSDVTLMISIYNKRSMKRKEMIGWISMGQNSSGEEEQSHWQEMKESKGLQVCRWHTLLES", "length": 582, "header": "tr|A0A8V0Z4I6-1|A0A8V0Z4I6_CHICK Computationally mapped isoform of Synaptotagmin 16 OS=Gallus gallus OX=9031 GN=SYT16 PE=3 SV=1 CANONICAL=A0A8V0Z3E1-1" }, "locus": { "chromosome": "5", "start_pos": 53406060, "end_pos": 53368959, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042929.1", "url": "https://www.ensembl.org/id/ENSGALT00010042929.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025419.1", "url": "https://www.ensembl.org/id/ENSGALP00010025419.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K644-1", "protein_name": "Synaptotagmin 16", "gene_name": "Syt16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLVMASQDVQNFFQPLSSWLSRVYEALQQAGDALSASLVLLSKHDSALSDKPEQDLDAIQIQETCLEDGEQDNDGGPEETGSLFLEEDHFSSSNSDLRDSVQTASLRLGQQAKDSSTVISQWPNKIPGGPKPPHVLSSIAEEEHHSEGQRCDLQHGSDTQLPGSLEKVNGRKQANSFGDDEEPSTSSESDEDVTKQFEISVSRSQSFRTGVPEKGKTTELEQKTKCKHFLCTHQEDSAEGSACEDLDGPSQLSYSEIRSYEDRPISILSQSPCESRDTRHHGPCHLGAGVVRNLSRPCADGILETETAFISRGFEDPYATHNSSMWSPEEQDGTSLQVPPRLPEPISKCGDLDVIFEYRAVTQKLTVTIVRAQGLPDKDRSGVNSWQVHIVLLPSKKQRGKTNIQRGPNPVFKEKVTFTKLEPRDVAACAVRFRLYAARKMTRERMMGEKLFCLSHLHPEGEMKVTLVLEPRSNLSSGESPLSPSVVSHSDSASSTQSLSHGGVPELLVGLSYNATTGRLSVEMIKGSHFRNLAANRAPDTYGKLFLLNCVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISIYSRRTMKRKEMIGWIALGQNSSGEEEQEHWDEMKDSKSQQICRWHTLLES", "length": 644 }, "evidence": [ { "id": "A0A8V0Z3E1", "url": "https://omabrowser.org/oma/group/A0A8V0Z3E1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SRU3-1", "protein_name": "Synaptotagmin 16", "gene_name": "SYT16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPLAMASQDAQNFFQPLSSWISQVYEALQQARDALSASLVNFSKQDSKGSDKLDQDLDDIQIQETYFEDEEQSNDWTQEDTNSLFLEVDHFSCCNSDFQDSAQNSSPRLSRHAKDSCSVASQWPSQTLDDQKPPHVLSSIADEEHHLGKQRSGLQHDFDGQLSGILENVNGKKQVNKFGDDEELSTSSDTDEEVIKQFEISVSRSQSLRSGASEKGRQAGLEQKPKARRWLSTHKEDSKEVPACKGLDGASQPNYSEHLSYGEDGPISAHSWSPSELGDTRQQGTSPQETCVVRCLSRQSTEGSLEMEAAFNNRGFEDSYATDSSSVWSPEEQDRTSFQVPSGVPEPISKCGDLDVIFEYRAASQKLTVTIVRAQGLPDKDRSGVNSWQVHVVLLPNKKQRGRTGIQRGPNPIFKEKVTFAKLEPRDVAACAVRFRLYAARKMTRERMMGEGLFYLSHLHQEGEMKVTLVLEPRSNISGGESPLSPSAVSHSDSASSTQSLSHGGAPELLVGLSYNATTGRLSVEMIKGSHFRNLSVNRAPDTYGKLFLLNSVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISVYNRRTMKRKEMIGWIALGQNSSGEEERDHWEEMKETKGQQVCRWHTLLES", "length": 645 }, "evidence": [ { "id": "A0A8V0Z3E1", "url": "https://omabrowser.org/oma/group/A0A8V0Z3E1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q17RD7-1", "protein_name": "Synaptotagmin-16", "gene_name": "SYT16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLAMASQDVQNFFQPFSSWISRVYEALQQAGDMLSASLVNISKQDSKLSDKLDQDLDNIQIQETYFEDEEQDNDWSQEDANSLFLEVDHFSCCNSDLQDSAQNSSPSLSQHAKDSCSTMSQWPNWASDDRKLPHVLSSIAEEEHHLEKQRSGLQHGFDSQLPGTLETVNGKKQVNSFGDDEELSTSSDSDEEVIKQFEISVSRSQSFRSVTSEKGKQTGLEQKPKFSRSLLTHGEDGTEVSACEDLDGASQRRYSENLSYGEDDHIPAHSQSPCERGDAKHHGTSHQESSVVQSLRRQSTEGSLEMETAFNSRGFEDSYATDSSSMWSPEEQDRTNLQVPSGVSEPISKCGDLDVIFEYRAASQKLTVTIVRAQGLPDKDRSGVNSWQVHVVLLPGKKHRGRTNIQRGPNPVFREKVTFAKLEPRDVAACAVRFRLYAARKMTRERMMGEKLFYLSHLHPEGEMKVTLVLEPRSNISSGGSPLSPSAVSHSDSTSSTQSLSHGGAPELLVGLSYNATTGRLSVEMIKGSHFRNLAVNRAPDTYGKLFLLNSVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISVYNRRTMKRKEMIGWIALGQNSSGEEEQDHWEEMKETKGQQICRWHTLLES", "length": 645 }, "evidence": [ { "id": "A0A8V0Z3E1", "url": "https://omabrowser.org/oma/group/A0A8V0Z3E1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TN83-1", "protein_name": "Synaptotagmin-16", "gene_name": "Syt16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLTMASQDVQNFFQPLSSWLSRVYEALQQAGDALSASLVLLSKHDSALSDKPEQDLDAAQIQQTYLEDEEQDHDGSPEEASSLFLEEDHFSLSNSDLQDSVQTASPTLGQQAEDSSSVIPPWPSKIPGAPKPQPVLSSIAEEDHHSERQRCGRQHGSGTLEKVNGRKQVNSFGDDEEPSTSSESDEDVTKQFKISVSRSQSFRSGVSEKGKTTELEQKIKCKRLLCTHQEDSAEGSACEDLDRTSQLSYSEILSYEDRPISILPQSPFESRNVRHHGPCRPEMGMVRSLGRPCADGVLETETAFVSRGFEDSYATHSSSLWSPEEQDGTSLQVPHRLLEPISKCGDLDVIFEYRAVTQKLTVTIVRAQGLPDKDRSGVNSWQVHIVLLPSKKQRGKTNIQRGPNPVFKEKVTFTKLEPRDVASCAVRFRLYAARKMTRERMMGEKLFCLSHLHPEGEMKVTLVLEPRSNLSSGESPLSPSVVSHSDSASSTQSLSHGGVPELLVGLSYNATTGRLSVEMIKGSHFRNLAANRAPDTYGKLFLLNCVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISIYSRRTMKRKEMIGWVALGQNSSGEEEQEHWEEMKESKGQQTCRWHTLLES", "length": 639 }, "evidence": [ { "id": "A0A8V0Z3E1", "url": "https://omabrowser.org/oma/group/A0A8V0Z3E1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3E1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E1" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 287, "end_pos": 406, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 395, "end_pos": 397 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 453, "end_pos": 455 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3E3-1", "uniprot_ac": "A0A8V0Z3E3", "uniprot_id": "A0A8V0Z3E3_CHICK", "mass": { "chemical_mass": 14924.0, "monoisotopic_mass": 14924.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Bcl-x interacting BH3 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E3/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E3", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z3E3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3E3", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR015040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PF08945", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08945", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z3E3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "GMKSPQVCSECTVSNCGFLLSAAETAALRFVPVSNALFLLCAASRWRSHSLAEEIQPEIWIAQELRRIGDEFNASYCPRRVIFLFLLSISLRTVSKREKLNHIWKLALWQVFCSLKCRKGCAGGCRLLPPRH", "length": 132, "header": "tr|A0A8V0Z3E3-1|A0A8V0Z3E3_CHICK Isoform 1 of Bcl-x interacting BH3 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z3E3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3E3/entry#A0A8V0Z3E3-1", "sequence": { "sequence": "GMKSPQVCSECTVSNCGFLLSAAETAALRFVPVSNALFLLCAASRWRSHSLAEEIQPEIWIAQELRRIGDEFNASYCPRRVIFLFLLSISLRTVSKREKLNHIWKLALWQVFCSLKCRKGCAGGCRLLPPRH", "length": 132, "header": "tr|A0A8V0Z3E3-1|A0A8V0Z3E3_CHICK Isoform 1 of Bcl-x interacting BH3 domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z3E3-1" }, "locus": { "chromosome": "3", "start_pos": 3314710, "end_pos": 3314023, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010039918.1", "url": 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"end_pos": 80, "start_aa": "Ser", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3F6-1", "uniprot_ac": "A0A8V0Z3F6", "uniprot_id": "A0A8V0Z3F6_CHICK", "mass": { "chemical_mass": 99809.0, "monoisotopic_mass": 99809.0 }, "refseq": {}, "gene_names": [ { "name": "SLC12A9", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F6" } ] } ], "protein_names": [ { "name": "Solute carrier family 12 member 9", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3F6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SLC12A9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F6", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z3F6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3F6", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR004841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3F6", "url": "https://www.orthodb.org/?gene=A0A8V0Z3F6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3X2", "url": "https://www.orthodb.org/?gene=A0A8V0Z3X2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3Y4", "url": "https://www.orthodb.org/?gene=A0A8V0Z3Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11827:SF96", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11827:SF96", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z3F6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3X2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3X2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDIGGTCGLGPTWGRQQPFGGTPVLGCPDPAQAEARTGTGKAFPLSLSACRKPWAGVGCVPGGPEGALSPFMWLWDILSCEMGGFVVGHAGLYQALAMFAVAYFIIGMTVLSVCAIATNGALDAGGAYYMISRALGPEFGGSIGIMFFLANVCGSALYLLGLVEAVVDSFGIPPGQEVGSGIHVLPRSYWYELLYGTILLALCLVVCLVGASIYAKATFLIFLIVAGVLGTILVSFFVTRPLGVPIRMQHLNSSEIENGSFTGFSLATLRENLGGGYGVDYTTGQMMSFSTVFAVMFNGCTGIMAGSNMSGDLKRPSYSIPRGTISAVLFTYLVYNLLAFLMCATCNRTLLQKDYGFLRDISIFPPLVTVGIYAATLSAAMSNLIGASRILYALARDDLFGRALTLAKKTSASGNPIMAVILSWLVVQLVLFSGKLNTIAGVVTTFFLLVYATVNLACLALEWASAPNFRPTFRYFSWHTCLLGIAGCCVMMFLISPVSASASLGFLLILLLALHYLSPSSTWGYISQALIFHQVRKYLLMLDVRKDHVKFWRPQMLLMVQNPRGSARLIDFVNDLKKSGLYVLGHVELQDLDTLPSDPLQPQQDSWLSLVDKLNVKAFISLTLAPSVRHGVRQLLFTSGLGGMRPNTLVLGFYDDAAPQDSLAQHPAFTSAREELPLGFPPLRAATTPKLLSPREYVGIVADALKMLRNVLLVRHLESLDKVWELRRAASPPPSIHVWPVNLLRPDSARYADTCSLFLLQMACVLNMARAWRRARLRLFLCVEAGAMPHAQEDKLRQLLKDLRIQAQIQLVPWDGVVRLHWQAPRGPPGGPAPAEEEETAVNFPPNTTQVSDEYVCAANKMVLEQGPAPAVRFLYLPRPPADTGLYPLYLRQLELLTRDLGPTVLVHGVSAVTSTQL", "length": 919, "header": "tr|A0A8V0Z3F6-1|A0A8V0Z3F6_CHICK Isoform 1 of Solute carrier family 12 member 9 OS=Gallus gallus OX=9031 GN=SLC12A9 PE=1 SV=1 CANONICAL=A0A8V0Z3F6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F6/entry#A0A8V0Z3F6-1", "sequence": { "sequence": "MEDIGGTCGLGPTWGRQQPFGGTPVLGCPDPAQAEARTGTGKAFPLSLSACRKPWAGVGCVPGGPEGALSPFMWLWDILSCEMGGFVVGHAGLYQALAMFAVAYFIIGMTVLSVCAIATNGALDAGGAYYMISRALGPEFGGSIGIMFFLANVCGSALYLLGLVEAVVDSFGIPPGQEVGSGIHVLPRSYWYELLYGTILLALCLVVCLVGASIYAKATFLIFLIVAGVLGTILVSFFVTRPLGVPIRMQHLNSSEIENGSFTGFSLATLRENLGGGYGVDYTTGQMMSFSTVFAVMFNGCTGIMAGSNMSGDLKRPSYSIPRGTISAVLFTYLVYNLLAFLMCATCNRTLLQKDYGFLRDISIFPPLVTVGIYAATLSAAMSNLIGASRILYALARDDLFGRALTLAKKTSASGNPIMAVILSWLVVQLVLFSGKLNTIAGVVTTFFLLVYATVNLACLALEWASAPNFRPTFRYFSWHTCLLGIAGCCVMMFLISPVSASASLGFLLILLLALHYLSPSSTWGYISQALIFHQVRKYLLMLDVRKDHVKFWRPQMLLMVQNPRGSARLIDFVNDLKKSGLYVLGHVELQDLDTLPSDPLQPQQDSWLSLVDKLNVKAFISLTLAPSVRHGVRQLLFTSGLGGMRPNTLVLGFYDDAAPQDSLAQHPAFTSAREELPLGFPPLRAATTPKLLSPREYVGIVADALKMLRNVLLVRHLESLDKVWELRRAASPPPSIHVWPVNLLRPDSARYADTCSLFLLQMACVLNMARAWRRARLRLFLCVEAGAMPHAQEDKLRQLLKDLRIQAQIQLVPWDGVVRLHWQAPRGPPGGPAPAEEEETAVNFPPNTTQVSDEYVCAANKMVLEQGPAPAVRFLYLPRPPADTGLYPLYLRQLELLTRDLGPTVLVHGVSAVTSTQL", "length": 919, "header": "tr|A0A8V0Z3F6-1|A0A8V0Z3F6_CHICK Isoform 1 of Solute carrier family 12 member 9 OS=Gallus gallus OX=9031 GN=SLC12A9 PE=1 SV=1 CANONICAL=A0A8V0Z3F6-1" }, "locus": { "chromosome": "9", "start_pos": 15290146, "end_pos": 15282460, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043155.1", "url": "https://www.ensembl.org/id/ENSGALT00010043155.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025630.1", "url": "https://www.ensembl.org/id/ENSGALP00010025630.1" } ] } }, { "isoform_ac": "A0A8V0Z3X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F6/entry#A0A8V0Z3X2-1", "sequence": { "sequence": "MASSERSALLTYRLCGGSGEDERGRERGRAAAAATPRKLPTFLGVVVPTLLSMFSVVLFLRLGFVVGHAGLYQALAMFAVAYFIIGMTVLSVCAIATNGALDAGGAYYMISRALGPEFGGSIGIMFFLANVCGSALYLLGLVEAVVDSFGIPPGQEVGSGIHVLPRSYWYELLYGTILLALCLVVCLHLNSSEIENGSFTGFSLATLRENLGGGYGVDYTTGQMMSFSTVFAVMFNGCTGIMAGSNMSGDLKRPSYSIPRGTISAVLFTYLVYNLLAFLMCATCNRTLLQKDYGFLRDISIFPPLVTVGIYAATLSAAMSNLIGASRILYALARDDLFGRALTLAKKTSASGNPIMAVILSWLVVQLVLFSGKLNTIAGVVTTFFLLVYATVNLACLALEWASAPNFRPTFRYFSWHTCLLGIAGCCVMMFLISPVSASASLGFLLILLLALHYLSPSSTWGYISQALIFHQVRKYLLMLDVRKDHVKFWRPQMLLMVQNPRGSARLIDFVNDLKKSGLYVLGHVELQDLDTLPSDPLQPQQDSWLSLVDKLNVKAFISLTLAPSVRHGVRQLLFTSGLGGMRPNTLVLGFYDDAAPQDSLAQHPAFTSAREELPLGFPPLRAATTPKLLSPREYVGIVADALKMLRNVLLVRHLESLDKVWELRRAASPPPSIHVWPVNLLRPDSARYADTCSLFLLQMACVLNMARAWRRARLRLFLCVEAGAMPHAQEDKLRQLLKDLRIQAQIQLVPWDGVVRLHWQAPRGPPGGPAPAEEEETAVNFPPNTTQVSDEYVCAANKMVLEQGPAPAVRFLYLPRPPADTGLYPLYLRQLELLTRDLGPTVLVHGVSAVTSTQL", "length": 856, "header": "tr|A0A8V0Z3X2-1|A0A8V0Z3X2_CHICK Computationally mapped isoform of Solute carrier family 12 member 9 OS=Gallus gallus OX=9031 GN=SLC12A9 PE=1 SV=1 CANONICAL=A0A8V0Z3F6-1" }, "locus": { "chromosome": "9", "start_pos": 15291019, "end_pos": 15282460, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043134.1", "url": "https://www.ensembl.org/id/ENSGALT00010043134.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025617.1", "url": "https://www.ensembl.org/id/ENSGALP00010025617.1" } ] } }, { "isoform_ac": "A0A8V0Z3Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3F6/entry#A0A8V0Z3Y4-1", "sequence": { "sequence": "MASSERSALLTYRLCGGSGEDERGRERGRAAAAATPRKLPTFLGVVVPTLLSMFSVVLFLRLGFVVGHAGLYQALAMFAVAYFIIGMTVLSVCAIATNGALDAGGAYYMISRALGPEFGGSIGIMFFLANVCGSALYLLGLVEAVVDSFGIPPGQEVGSGIHVLPRSYWYELLYGTILLALCLVVCLVGASIYAKATFLIFLIVAGVLGTILVSFFVTRPLGVPIRMQHLNSSEIENGSFTGFSLATLRENLGGGYGVDYTTGQMMSFSTVFAVMFNGCTGIMAGSNMSGDLKRPSYSIPRGTISAVLFTYLVYNLLAFLMCATCNRTLLQKDYGFLRDISIFPPLVTVGIYAATLSAAMSNLIGASRILYALARDDLFGRALTLAKKTSASGNPIMAVILSWLVVQLVLFSGKLNTIAGVVTTFFLLVYATVNLACLALEWASAPNFRPTFRYFSWHTCLLGIAGCCVMMFLISPVSASASLGFLLILLLALHYLSPSSTWGYISQALIFHQVRKYLLMLDVRKDHVKFWRPQMLLMVQNPRGSARLIDFVNDLKKSGLYVLGHVELQDLDTLPSDPLQPQQDSWLSLVDKLNVKAFISLTLAPSVRHGVRQLLFTSGLDLRALSSGGMRPNTLVLGFYDDAAPQDSLAQHPAFTSAREELPLGFPPLRAATTPKLLSPREYVGIVADALKMLRNVLLVRHLESLDKVWELRRAASPPPSIHVWPVNLLRPDSARYADTCSLFLLQMACVLNMARAWRRARLRLFLCVEAGAMPHAQEDKLRQLLKDLRIQAQIQLVPWDGVVRLHWQAPRGPPGGPAPAEEEETAVNFPPNTTQVSDEYVCAANKMVLEQGPAPAVRFLYLPRPPADTGLYPLYLRQLELLTRDLGPTVLVHGVSAVTSTQL", "length": 904, "header": "tr|A0A8V0Z3Y4-1|A0A8V0Z3Y4_CHICK Computationally mapped isoform of 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"refseq": { "ac": "XP_414816", "name": "glucose-induced degradation protein 4 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414816" }, "gene_names": [ { "name": "GID4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G6" } ] }, { "name": "GID4", "type": "synonym", "evidence": [ { "id": "XP_414816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414816" } ] } ], "protein_names": [ { "name": "GID complex subunit 4 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G6/entry#names_and_taxonomy" } ] }, { "name": "glucose-induced degradation protein 4 homolog", "type": "synonym", "evidence": [ { "id": "XP_414816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414816" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Nov 16, 2006 this sequence version replaced XP_414816.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_414816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414816" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GID4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G6", "locus": { "chromosome": "14", "start_pos": 5006275, "end_pos": 5000421, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017592", "url": "https://www.ensembl.org/id/ENSGALG00010017592" } ] } } ], "crossref": [ { "id": "A0A8V0Z3G6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3G6", "database": "AlphaFoldDB", "categories": [] }, { "id": "416512", "url": 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"Protein Classification" ] }, { "id": "PF09783", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09783", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_414816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_414816", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3G6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVRSERCRAGGAAGTASSAPSGAAASSLVPPPPINTAQPGVATSLLYSGAKFRGQQRSKGNAYEVEVVMQHVDMENSYLCGYLKIKGLTEEYPTLTTFFEGEIISKKHPFLTRKWDADEDVDRKHWGKFQAFYQYAKTFNSDDFDYEDLKNGDYVFMRWKEQFLVPDHTIKDISGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNLTHVPEHSAPIYEFR", "length": 225, "header": "tr|A0A8V0Z3G6-1|A0A8V0Z3G6_CHICK Isoform 1 of GID complex subunit 4 homolog OS=Gallus gallus OX=9031 GN=GID4 PE=3 SV=1 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"https://www.uniprot.org/uniprotkb/A0A8V0Z3G6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G6" } ], "pmid": "" }, { "name": "GID complex", "id": "GO:0034657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034657", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3G6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3G6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": 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This record is derived from a genomic sequence (NC_052574.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040518596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518596" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RP9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H3", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z3H3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3H3", "database": "AlphaFoldDB", "categories": [] }, { "id": "420747", "url": "https://www.ncbi.nlm.nih.gov/gene/420747", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR034585", "url": 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"MSHGLRRGREEGEEGAARGSQARHGSLHESAAGGGRSQGRHERKRKKEEAQQLQKLQHLESFYEKPPPGLIKEDETKPEDCIPDVPGNESAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRETKRHEKEMRIQQLKQLLEDSTSEDDSSDDSDEDDDEDSSSSTSSDKHKKKKRKKEKKKKEKKKKKKRKHK", "length": 228, "header": "tr|A0A8V0Z3H3-1|A0A8V0Z3H3_CHICK Isoform 1 of RP9 pre-mRNA splicing factor OS=Gallus gallus OX=9031 GN=RP9 PE=1 SV=1 CANONICAL=A0A8V0Z3H3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H3/entry#A0A8V0Z3H3-1", "sequence": { "sequence": "MSHGLRRGREEGEEGAARGSQARHGSLHESAAGGGRSQGRHERKRKKEEAQQLQKLQHLESFYEKPPPGLIKEDETKPEDCIPDVPGNESAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRETKRHEKEMRIQQLKQLLEDSTSEDDSSDDSDEDDDEDSSSSTSSDKHKKKKRKKEKKKKEKKKKKKRKHK", "length": 228, "header": "tr|A0A8V0Z3H3-1|A0A8V0Z3H3_CHICK Isoform 1 of RP9 pre-mRNA splicing factor OS=Gallus gallus OX=9031 GN=RP9 PE=1 SV=1 CANONICAL=A0A8V0Z3H3-1" }, "locus": { "chromosome": "2", "start_pos": 47954816, "end_pos": 47948157, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046657.1", "url": "https://www.ensembl.org/id/ENSGALT00010046657.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027786.1", "url": "https://www.ensembl.org/id/ENSGALP00010027786.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:420747", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:420747", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IJK4-1", "protein_name": "Retinitis pigmentosa 9 protein isoform X1", "gene_name": "rp9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDRKRRREHSEDKRERKKHKETRQDEDKYKHQTKKLIHEVQKLKHVETFYENAPPGFIKEDTEKPEDCIPDDPGNEDARSFLAHAPTKGLWMPLGKEVKVMQCWRCKKYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRENKRNEKETRIQQLKQLLQDTTSDSDSTSSSSSSSSSSDHSRKKKKKKKEKRKKEKKKHKKKKKKQKVRAGSDSDSD", "length": 222 }, "evidence": [ { "id": "A0A8V0Z3H3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A287BF00-1", "protein_name": "RP9 pre-mRNA splicing factor", "gene_name": "RP9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSRPGRDDAGNRGARRPREPQEQELQRRREQKRRRQDAQQLQQLKHLESFYEKPPPGLIKEDEAKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRENKRHEKDIRIQQLKQLLEDSTSEEDGSSSSSSECKEKHKKKKKKEKHKKKKKEKKKKKKRKHKSSKSNESSDSE", "length": 221 }, "evidence": [ { "id": "A0A8V0Z3H3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6A7C2-1", "protein_name": "RP9, pre-mRNA splicing factor", "gene_name": "Rp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGAGSRRPREPPEHELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGFIKEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGREVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRENKRHEKDVRIQQLKQLLEDSTSDDDGSSSSGDREKHKKRKKKEKHKKRKKEKKKKKKRKHKASKSHESSDSK", "length": 211 }, "evidence": [ { "id": "A0A8V0Z3H3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P97762-1", "protein_name": "Retinitis pigmentosa 9 protein homolog", "gene_name": "rp9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSGAGSRRPREPPEHELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGFIKEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGREVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRENKRHEKDVRIQQLKQLLEDSTSDDDGSSSSSSGDREKRKKRKKKEKHKKRKKEKKKKKKRKHKASKSSESSDSE", "length": 213 }, "evidence": [ { "id": "A0A8V0Z3H3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TA86-1", "protein_name": "Retinitis pigmentosa 9 protein", "gene_name": "RP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSRPGREDVGAAGARRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLIKEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE", "length": 221 }, "evidence": [ { "id": "A0A8V0Z3H3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 88, "end_pos": 90, 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N-terminal", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 65, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z537-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQGGKRTRGAVPMVCLSCPVMLLLLQLAGGAPIGQGLYPMPASVLQALSSRGTLVLEAALRSALMALEEALAEQQKQRGACGLCAPCLFPPCANITQRCPPPAVPPAMPPSCQALLDAQELPELPQRHWALSQACSPYLRLCPLQGTQPACTLLSAQRCQHRLQECLLAKAAPNPSMAAAMPERCGSREDPPPNSTAPRGRIMGGNVARHGAWPWLVSVRLHGELVCGGVLVSRAWALTAAHCFNGNQNELAWTVVVGDHELGKADPGERAVPVRRIVPHPKFNPKTFHGDLALLELAEPLAPSGTVSPVCLPSGTTEPSPGTPCHIAGWGSLYEEGPSAEVVMEAQVPLLSQETCRAALGRELLTSTMFCAGYLSGGIDSCQGDSGGPLVCQDPSSHSFVLYGITSWGDGCGERGKPGVYTRVAAFADWLSLQMNPVPGSREPSCFDLLALSQLAPEQQPLERTRLCSFYERSCRAAPGQASCTHIADETCRARLRRCELHSYTQTLVGLLRRAGDFIRNQLDFSFLTRTLPQLLGKIYGHLFPARVRRDAPDPAMAEHPTSEGPLRPPHRQLPTFREFFGSVGPRLQDWVQALRATAGGSAQAPTPDGEQLPEETWLFLQQGEELVEELLGQGRAFLTQLRAELDLDTSLEVMQTPGEPTEGPVGNPVLNWSVLREKRELVPTVPGLEEEEGEKAGTGRACPGLNASALRVGVVQELYAWVLQVPQPDLAMTFQEILVDLSSKNTKGLYRAQVRATVGGRPTAFTGLVGLESDSLARSMPGLVALALEALKT", "length": 795, "header": "tr|A0A8V0Z537-1|A0A8V0Z537_CHICK Isoform 1 of Serine protease 56 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z537-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z537/entry#A0A8V0Z3H5-1", "sequence": { "sequence": "MEQGGKRTRGAVPMVCLSCPVMLLLLQLAGGAPIGQGLYPMPASVLQALSSRGTLVLEAALRSALMALEEALAEQQKQRGACGLCAPCLFPPCANITQRCPQRCGSREDPPPNSTAPRGRIMGGNVARHGAWPWLVSVRLHGELVCGGVLVSRAWALTAAHCFNGNQNELAWTVVVGDHELGKADPGERAVPVRRIVPHPKFNPKTFHGDLALLELAEPLAPSGTVSPVCLPSGTTEPSPGTPCHIAGWGSLYEEGPSAEVVMEAQVPLLSQETCRAALGRELLTSTMFCAGYLSGGIDSCQGDSGGPLVCQDPSSHSFVLYGITSWGDGCGERGKPGVYTRVAAFADWLSLQMNPVPGSREPSCFDLLALSQLAPEQQPLERTRLCSFYERSCRAAPGQASCTHIADETCRARLRRCELHSYTQTLVGLLRRAGDFIRNQLDFSFLTRTLPQLLGKIYGHLFPARVRRDAPDPAMAEHPTSEGPLRPPHRQLPTFREFFGSVGPRLQDWVQALRATAGGSAQAPTPDGEQLPEETWLFLQQGEELVEELLGQGRAFLTQLRAELDLDTSLEVMQTPGEPTEGPVGNPVLNWSVLREKRELVPTVPGLEEEEGEKAGTGRACPGLNASALRVGVVQELYAWVLQVPQPDLAMTFQEILVDLSSKNTKGLYRAQVRATVGGRPTAFTGLVGLESDSLARSMPGLVALALEALKT", "length": 713, "header": "tr|A0A8V0Z3H5-1|A0A8V0Z537_CHICK Computationally mapped isoform of Serine protease 56 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z537-1" }, "locus": { "chromosome": "9", "start_pos": 15298224, "end_pos": 15292875, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043183.1", "url": "https://www.ensembl.org/id/ENSGALT00010043183.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025650.1", "url": "https://www.ensembl.org/id/ENSGALP00010025650.1" } ] } }, { "isoform_ac": "A0A8V0Z537-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z537/entry#A0A8V0Z537-1", "sequence": { "sequence": "MEQGGKRTRGAVPMVCLSCPVMLLLLQLAGGAPIGQGLYPMPASVLQALSSRGTLVLEAALRSALMALEEALAEQQKQRGACGLCAPCLFPPCANITQRCPPPAVPPAMPPSCQALLDAQELPELPQRHWALSQACSPYLRLCPLQGTQPACTLLSAQRCQHRLQECLLAKAAPNPSMAAAMPERCGSREDPPPNSTAPRGRIMGGNVARHGAWPWLVSVRLHGELVCGGVLVSRAWALTAAHCFNGNQNELAWTVVVGDHELGKADPGERAVPVRRIVPHPKFNPKTFHGDLALLELAEPLAPSGTVSPVCLPSGTTEPSPGTPCHIAGWGSLYEEGPSAEVVMEAQVPLLSQETCRAALGRELLTSTMFCAGYLSGGIDSCQGDSGGPLVCQDPSSHSFVLYGITSWGDGCGERGKPGVYTRVAAFADWLSLQMNPVPGSREPSCFDLLALSQLAPEQQPLERTRLCSFYERSCRAAPGQASCTHIADETCRARLRRCELHSYTQTLVGLLRRAGDFIRNQLDFSFLTRTLPQLLGKIYGHLFPARVRRDAPDPAMAEHPTSEGPLRPPHRQLPTFREFFGSVGPRLQDWVQALRATAGGSAQAPTPDGEQLPEETWLFLQQGEELVEELLGQGRAFLTQLRAELDLDTSLEVMQTPGEPTEGPVGNPVLNWSVLREKRELVPTVPGLEEEEGEKAGTGRACPGLNASALRVGVVQELYAWVLQVPQPDLAMTFQEILVDLSSKNTKGLYRAQVRATVGGRPTAFTGLVGLESDSLARSMPGLVALALEALKT", "length": 795, "header": "tr|A0A8V0Z537-1|A0A8V0Z537_CHICK Isoform 1 of Serine protease 56 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z537-1" }, "locus": { "chromosome": "9", "start_pos": 15298224, "end_pos": 15292875, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043178.1", "url": "https://www.ensembl.org/id/ENSGALT00010043178.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025646.1", "url": "https://www.ensembl.org/id/ENSGALP00010025646.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9855719", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9855719", "resource": "Reactome", "description": "Regulation of FXIIa and plasma kallikrein activity" }, { "id": "R-GGA-9935598", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9935598", "resource": "Reactome", "description": "FXIIa, PKa-dependent activation of coagulation pathway" }, { "id": "R-GGA-9970672", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9970672", "resource": "Reactome", "description": "FXIIa activates plasma kallikrein-kinin system" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z537", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z537" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z537", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z537" } ], "pmid": "" }, { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z537", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z537" } ], "pmid": "" }, { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z537", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z537" } ], "pmid": "" }, { "name": "zymogen activation", "id": "GO:0031638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031638", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z537", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z537" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z537", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z537" } ], "pmid": "" }, { "name": "rough endoplasmic reticulum", "id": "GO:0005791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z537", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z537" } ], "pmid": "" } ] } ] }, 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052537.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_421678.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_421678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421678" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYP26C1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9", "locus": { "chromosome": "6", "start_pos": 21362457, "end_pos": 21369523, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017781", "url": "https://www.ensembl.org/id/ENSGALG00010017781" } ] } } ], "crossref": [ { "id": "A0A8V0Z3H9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3H9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20636", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20636", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423806", "url": "https://www.ncbi.nlm.nih.gov/gene/423806", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "MIIHSTR", "url": "https://omabrowser.org/oma/group/MIIHSTR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3H9", "url": "https://www.orthodb.org/?gene=A0A8V0Z3H9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24286", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24286", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24286:SF100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24286:SF100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-211916", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211916", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5365859", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5365859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_421678", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_421678", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAGLCWPAAAALALLFLALLLALCRHLWALRWSLSRDRASALPLPKGSMGWPFFGETLHWLLQGSRFHSSRRERYGNVFKTHLLGRPVVRVTGAENVRKILLGEHTLVSAQWPQSTQILLGSHTLLGSTGDLHRQRRKILARVFCRAALESYLPRIQKVVSWELRGWCMQPGSIAVYSSAKTLTFRIAAQILLGLRLEEKQFKDLAKTFEQLVENLFSLPLNVPFSGLRKGIKARDMLHEFMERAIQEKLQRAISEEHSDALDFIINSAKEHGKEFTMQELKESAIELIFAAFFTTASASTSLILLLLKHPSAIEKIRQELVSHELYPQHQNCPMAPCPGTGRDSEQQLLTTASDAHEDQLQLPDLTEETELGGGCSPNLPALLEPMHPPSSPQPRGCRCPLDISLEQLSRLRYLDCVVKEVLRVLPPVSGGYRTALQTFELDGYQIPKGWSVMYSIRDTHETAAIYQSPPGGFDPDRFNVTHLEAAGRFHYIPFGGGARSCIGKELAQAILKLLAIELVTTARWELATPTFPAMQTVPIVHPVDGLQLYFHPLWPSHGGEA", "length": 563, "header": "tr|A0A8V0Z3H9-1|A0A8V0Z3H9_CHICK Isoform 1 of Cytochrome P450 family 26 subfamily C member 1 OS=Gallus gallus OX=9031 GN=CYP26C1 PE=3 SV=1 CANONICAL=A0A8V0Z3H9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9/entry#A0A8V0Z3H9-1", "sequence": { "sequence": "MPAGLCWPAAAALALLFLALLLALCRHLWALRWSLSRDRASALPLPKGSMGWPFFGETLHWLLQGSRFHSSRRERYGNVFKTHLLGRPVVRVTGAENVRKILLGEHTLVSAQWPQSTQILLGSHTLLGSTGDLHRQRRKILARVFCRAALESYLPRIQKVVSWELRGWCMQPGSIAVYSSAKTLTFRIAAQILLGLRLEEKQFKDLAKTFEQLVENLFSLPLNVPFSGLRKGIKARDMLHEFMERAIQEKLQRAISEEHSDALDFIINSAKEHGKEFTMQELKESAIELIFAAFFTTASASTSLILLLLKHPSAIEKIRQELVSHELYPQHQNCPMAPCPGTGRDSEQQLLTTASDAHEDQLQLPDLTEETELGGGCSPNLPALLEPMHPPSSPQPRGCRCPLDISLEQLSRLRYLDCVVKEVLRVLPPVSGGYRTALQTFELDGYQIPKGWSVMYSIRDTHETAAIYQSPPGGFDPDRFNVTHLEAAGRFHYIPFGGGARSCIGKELAQAILKLLAIELVTTARWELATPTFPAMQTVPIVHPVDGLQLYFHPLWPSHGGEA", "length": 563, "header": "tr|A0A8V0Z3H9-1|A0A8V0Z3H9_CHICK Isoform 1 of Cytochrome P450 family 26 subfamily C member 1 OS=Gallus gallus OX=9031 GN=CYP26C1 PE=3 SV=1 CANONICAL=A0A8V0Z3H9-1" }, "locus": { "chromosome": "6", "start_pos": 21369518, "end_pos": 21364002, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042970.1", "url": "https://www.ensembl.org/id/ENSGALT00010042970.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025461.1", "url": "https://www.ensembl.org/id/ENSGALP00010025461.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-211916", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-211916", "resource": "Reactome", "description": "Vitamins" }, { "id": "R-GGA-5365859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5365859", "resource": "Reactome", "description": "RA biosynthesis pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IE06-1", "protein_name": "Cytochrome P450 26C1", "gene_name": "LOC100755258", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLSWGLSCLSMLGAAGTALLCAGVLLGLAQNLWTLRWTLSRDPASTLPLPKGSMGWPFLGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRQRRKVLARVFSRPALERFVPRLQRALRREVRSWCAARGPVAVYGAAKALTFRMAARILLGLQLDETRCTELAQTFEQLVENLFSLPLDVPFSGLRKGIRARDQLYQYLDEAIAQKLHEEQAAEPGDALHLIINSARELGHELSVQELKESAVELLFAAFFTTASASTSLILLLLQHPAAIAKIQQELSAQGLGHACGCAPLATGPRPDCSCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTVLRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESEDTRGSCGRFHYIPFGGGARSCLGQKLAQAVLQLLAVELVRTARWELATPAFPVMQTVPILHPVDGLRLFFHPLETLGAGDGLHL", "length": 518 }, "evidence": [ { "id": "A0A8V0Z3H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B2RXA7-1", "protein_name": "Cytochrome P450 26C1", "gene_name": "Cyp26c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISWGLSCLSVLGAAGTTLLCAGLLLGLAQQLWTLRWTLSRDWASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRQRRKVLARVFSRSSLEQFVPRLQGALRREVRSWCAAQRPVAVYQAAKALTFRMAARILLGLQLDEARCTELAHTFEQLVENLFSLPLDVPFSGLRKGIRARDQLYEHLDEAVAEKLQEKQTAEPGDALLLIINSARELGHEPSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAITKIQQELSAQGLGRACTCTPRASGSPPDCGCEPDLSLAMLGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESGDARGSGGRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPVMQTVPIVHPVDGLLLFFHPLPTSGAGDGLPF", "length": 518 }, "evidence": [ { "id": "A0A8V0Z3H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4AAL3-1", "protein_name": "Cytochrome P450, family 26, subfamily C, polypeptide 1", "gene_name": "Cyp26c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSWGLSCLSMLGAAGTALLCAGLLLGLAQQLWTLRWTLSRDWASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGERHRQRRKVLARVFSRPALEQFVPRLQEALRREVRSWCAAQRPVAVYQAAKALTFRMAARILLGLQLDEARCTELAQTFERLVENLFSLPLDVPFSGLRKGIRARDQLYQHLDEVIAEKLREELTAEPGDALHLIINSARELGRELSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAIAKIQQELSAQGLGSPCSCAPRASGSRPDCSCEPDLSLAVLGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESEDARGSGGRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPVMQTVPIVHPVDGLLLLFHPLPTLGAGDGSPF", "length": 518 }, "evidence": [ { "id": "A0A8V0Z3H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BDT5-1", "protein_name": "Cytochrome P450 family 26 subfamily C member 1", "gene_name": "CYP26C1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLPWGLSCLSALGAVGTALLGAGLLLSLAQHLWTLRWTLSRDRASALPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTVLLGEHRLVRSQWPQSAHILLGSHTLLGAVGESHRQRRKILARAFSRAALECYVPRLQRALRREVRSWCAARGPVAVYEAAKALTFRMAARILLGLRLDEAQCSELARTFEQFVENLFSLPLDVPFSGLRKGIRARDQLHRHLEEAIAQKLLEDKTAVEPGDALDGIIHSTRELGHELSVQELKESAVELLFAAFSTTASASTSLVLLLLQHPAAIAKIQQELAAQGLGRACGCAPAASGGGAGPPPDCGCEPDLSLATLGHLRYVGCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWNVMYSIRDTHETAAVYRSPPEGFDPERFGTAGDDALGAAGRFHYIPFGGGARSCLGQELAQTVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLASPAAQDGQRL", "length": 523 }, "evidence": [ { "id": "A0A8V0Z3H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SC84-1", "protein_name": "Cytochrome P450 family 26 subfamily C member 1", "gene_name": "CYP26C1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFPWGLSSLSVLGAAGTALLCAGLLLSLAQHLWTLRWTLSRDRSSALPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRQRRKILARVFSRAALERYVPRLQGALRREVRSWCVARGPVAVYEAAKALTFRMAARILLGLRLEEEQCSELARTFERFVENLFSLPLDVPFSGLRKGIRARDQLHRHLEEAIAEKLHEDKAAEPGDALAGIIHSTRELGQELSVQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIVKIRQELAAQGLGRACGCAPGASGGGAGPRPDCGCEPDLSLAALGRLRYVGCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWNVMYSIRDTHETAAVYRSPPEGFDPERFHTAGEDARGAAGRFHYIPFGGGARSCLGQELAQTVLQLLAVELVRTARWELATPSFPAMQTVPIVHPVDGLRLFFYPLAPSAAQDGRRL", "length": 522 }, "evidence": [ { "id": "A0A8V0Z3H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q42569-1", "protein_name": "3beta,22alpha-dihydroxysteroid 3-dehydrogenase", "gene_name": "CYP90A1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAFTAFLLLLSSIAAGFLLLLRRTRYRRMGLPPGSLGLPLIGETFQLIGAYKTENPEPFIDERVARYGSVFMTHLFGEPTIFSADPETNRFVLQNEGKLFECSYPASICNLLGKHSLLLMKGSLHKRMHSLTMSFANSSIIKDHLMLDIDRLVRFNLDSWSSRVLLMEEAKKITFELTVKQLMSFDPGEWSESLRKEYLLVIEGFFSLPLPLFSTTYRKAIQARRKVAEALTVVVMKRREEEEEGAERKKDMLAALLAADDGFSDEEIVDFLVALLVAGYETTSTIMTLAVKFLTETPLALAQLKEEHEKIRAMKSDSYSLEWSDYKSMPFTQCVVNETLRVANIIGGVFRRAMTDVEIKGYKIPKGWKVFSSFRAVHLDPNHFKDARTFNPWRWQSNSVTTGPSNVFTPFGGGPRLCPGYELARVALSVFLHRLVTGFSWVPAEQDKLVFFPTTRTQKRYPIFVKRRDFAT", "length": 472 }, "evidence": [ { "id": "A0A8V0Z3H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6V0L0-1", "protein_name": "Cytochrome P450 26C1", "gene_name": "CYP26C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL", "length": 522 }, "evidence": [ { "id": "A0A8V0Z3H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z3H9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "retinoic acid 4-hydroxylase activity", "id": "GO:0008401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008401", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9" } ], "pmid": "" }, { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9" } ], "pmid": "" }, { "name": "retinoic acid binding", "id": "GO:0001972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001972", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9" } ], "pmid": "" }, { "name": "retinoic acid catabolic process", "id": "GO:0034653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034653", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3H9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 481, "end_pos": 483, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 481, "end_pos": 483 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3J5-1", "uniprot_ac": "A0A8V0Z3J5", "uniprot_id": "A0A8V0Z3J5_CHICK", "mass": { "chemical_mass": 89646.0, "monoisotopic_mass": 89646.0 }, "refseq": { "ac": "XP_040518588", "name": "uncharacterized protein LOC420748", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040518588" }, "gene_names": [ { "name": "LOC420748", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3J5" } ] }, { "name": "LOC420748", "type": "synonym", "evidence": [ { "id": "XP_040518588", "database": 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:: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052533.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040545224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545224" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CDK13", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4", "locus": { "chromosome": "2", "start_pos": 49952651, "end_pos": 49893714, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017880", "url": "https://www.ensembl.org/id/ENSGALG00010017880" } ] } } ], "crossref": [ { "id": "cd07864", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07864", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "420766", "url": "https://www.ncbi.nlm.nih.gov/gene/420766", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PKAYREE", "url": "https://omabrowser.org/oma/group/PKAYREE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3K4", "url": "https://www.orthodb.org/?gene=A0A8V0Z3K4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24056:SF459", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24056:SF459", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6796648", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6796648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040545224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040545224", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10216", "url": "https://www.rhea-db.org/rhea/10216", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSTSEAAAGGSGGSRGWGSGGGSAAAEAAADKKRLHHRRRKRFAAQPQPPPPPAPHPLLFPLLQPPLLQPPLLQPPLPPQSLLFLAATGASSCCGDGGERKRPRGKRRSGSRHKRRRGRGGGGGGGTQEAEKRRGSGGLSTLVEEYDDVSSQSEGLVGGGAAGGGAGSGAGSPASSPGGGGGSQRQRGEAERSGRSRREHRSGSGRSKERHREHRRRGEEKAQQEGAAAGRGGSEAASSSSKSRSRHNHAGGQDREGLKSGGGGGSDGRRKGSLASPGSGRKERESKAHRSRTKAAKEPPSAYKDPPKAYRDDKPEPKAYRRQRSSPSPGRDDSPPLHRSSQSLRSRKSLSPVGGRSPLSPYSRRRSPSYSRHSSYERGGDVSPSPYSSWRRSRSPYSPVIRRSAKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAAKASAKASNTSTPTKGNTDTAASAPQLNNVKDLKKVKIEHTPSPTSSTNLKNDKAKAKVLLPETKGENNLITEKNTKQKATAVKEDKVTVVKQQPVTVKEKTKPSTPSVVAKEKERIVALPASTLPPLPLPPTLPEDNETDSSLKENITVKSVKETEKKLRHLLADLPLPPELPGGAELGKSPEEKKPTVQLHSKRRPKICGPRHGETKEKEIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLNHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLAYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLAYFNTMKPKKQYRRKLREEFAFIPPAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQKQMGMTDDATATKVPRKDLSLGMDESRTNTPQGMQTSSQLKTQGNSSVALAKTSTGQQLNQNEVAILLNLLQSKTSVSLAQFAQVLNIKVNPETQQQLNKINLPAGILSAGEKQSEQQPPPPPPPPPEQESLKQPTVTQPPVPPAQLSQPKVETDAAQAAVQSAFAVLLSQLIKAQQTKQKDLVLEEKENGSGNEMSLQLRQPPEPTTPASLSRDDMESPATGYPHLIKSLYTPAGQEDLSRQSEMRLLNRTPEQERPRILPPDQRPPEPPEPPPLTDEDLDYRTENQHLPITNSSSGTDPHAGVKAALLQLLAQHQAQATTEEPVQTSVDYQARDSYVAGPDYKDNFGSSTFSSAHYGGSDGIGSGSSGALERRSFLGNSDIQPLDNYSTASSHSGGAPPPSAFSESFPSSVTGYGDIYLNAGPMLFSGDKDHRFEYSHGPISVLGNSRDASVGPESTHSLPTKMHNYSYGSNLQENPGGISHMHGQTWTSPAQGPGYSQGYRGHISTSAVRGRGRGLPF", "length": 1530, "header": "tr|A0A8V0Z3K4-1|A0A8V0Z3K4_CHICK Isoform 1 of Cyclin dependent kinase 13 OS=Gallus gallus OX=9031 GN=CDK13 PE=1 SV=1 CANONICAL=A0A8V0Z3K4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4/entry#A0A8V0Z3K4-1", "sequence": { "sequence": "MPSTSEAAAGGSGGSRGWGSGGGSAAAEAAADKKRLHHRRRKRFAAQPQPPPPPAPHPLLFPLLQPPLLQPPLLQPPLPPQSLLFLAATGASSCCGDGGERKRPRGKRRSGSRHKRRRGRGGGGGGGTQEAEKRRGSGGLSTLVEEYDDVSSQSEGLVGGGAAGGGAGSGAGSPASSPGGGGGSQRQRGEAERSGRSRREHRSGSGRSKERHREHRRRGEEKAQQEGAAAGRGGSEAASSSSKSRSRHNHAGGQDREGLKSGGGGGSDGRRKGSLASPGSGRKERESKAHRSRTKAAKEPPSAYKDPPKAYRDDKPEPKAYRRQRSSPSPGRDDSPPLHRSSQSLRSRKSLSPVGGRSPLSPYSRRRSPSYSRHSSYERGGDVSPSPYSSWRRSRSPYSPVIRRSAKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAAKASAKASNTSTPTKGNTDTAASAPQLNNVKDLKKVKIEHTPSPTSSTNLKNDKAKAKVLLPETKGENNLITEKNTKQKATAVKEDKVTVVKQQPVTVKEKTKPSTPSVVAKEKERIVALPASTLPPLPLPPTLPEDNETDSSLKENITVKSVKETEKKLRHLLADLPLPPELPGGAELGKSPEEKKPTVQLHSKRRPKICGPRHGETKEKEIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLNHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLAYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLAYFNTMKPKKQYRRKLREEFAFIPPAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQKQMGMTDDATATKVPRKDLSLGMDESRTNTPQGMQTSSQLKTQGNSSVALAKTSTGQQLNQNEVAILLNLLQSKTSVSLAQFAQVLNIKVNPETQQQLNKINLPAGILSAGEKQSEQQPPPPPPPPPEQESLKQPTVTQPPVPPAQLSQPKVETDAAQAAVQSAFAVLLSQLIKAQQTKQKDLVLEEKENGSGNEMSLQLRQPPEPTTPASLSRDDMESPATGYPHLIKSLYTPAGQEDLSRQSEMRLLNRTPEQERPRILPPDQRPPEPPEPPPLTDEDLDYRTENQHLPITNSSSGTDPHAGVKAALLQLLAQHQAQATTEEPVQTSVDYQARDSYVAGPDYKDNFGSSTFSSAHYGGSDGIGSGSSGALERRSFLGNSDIQPLDNYSTASSHSGGAPPPSAFSESFPSSVTGYGDIYLNAGPMLFSGDKDHRFEYSHGPISVLGNSRDASVGPESTHSLPTKMHNYSYGSNLQENPGGISHMHGQTWTSPAQGPGYSQGYRGHISTSAVRGRGRGLPF", "length": 1530, "header": "tr|A0A8V0Z3K4-1|A0A8V0Z3K4_CHICK Isoform 1 of Cyclin dependent kinase 13 OS=Gallus gallus OX=9031 GN=CDK13 PE=1 SV=1 CANONICAL=A0A8V0Z3K4-1" }, "locus": { "chromosome": "2", "start_pos": 49952072, "end_pos": 49893913, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043223.1", "url": "https://www.ensembl.org/id/ENSGALT00010043223.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025680.1", "url": "https://www.ensembl.org/id/ENSGALP00010025680.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 508, "start_aa": "Thr", "end_pos": 508, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr508", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-6796648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6796648", "resource": "Reactome", "description": "TP53 Regulates Transcription of DNA Repair Genes" }, { "id": "R-GGA-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BB52-1", "protein_name": "Cyclin-dependent kinase 13", "gene_name": "CDK13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKDRHREHRRRDGQRGGGEASKSRSRHGHGGEERAEAGKSGSSSSSGGRRKSASATSSSSSSRKDRDPKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRQRSLSPLGGRDDSPVSHRASQSLRNRKSPSPAGGGSSPYSRRLARSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVIRRSAKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKAAEAAAKAAKAASTSTPTKGNTETGASASQTNHVKDVKKLKTEHAPSPSSGGTLKNDKAKTKPPLQVTKVDNNLIVDKATKKAVVVGKESKSAATKEEPVSLKEKTKPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKKTATQLHNKRRPKICGPRFGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQKQMGMTDDVSTVKAPRKDLSLGMDDSRTSTPQSVLPSSQLKPQGNSNAAPVKTGPGQQLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATGEKQTDPSTPQQESSKPLGGIQPSQNMQPKVEPDAAQAAVQSAFAVLLTQLIKAQQSKQKDVLLEERENGSGHEAPLQLRPPPEPATPASGQDDLIQHQDMRLLELTPEPDRPRILPPDQRPPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKRESGIDYQAGDTYVPSSDYKDNFGSSSFSSAPYVSNDGLGSASAPPLERRSFMGNSDIQSLDNYSTTSSHSGGPPQPSAFSESFPSSVAGYGDIYLNTGPMLFSGDKDHRFEYSHGPIAVLANSSDPSTGPESTHPLPAKMHNYNYGGSLQETPGGHGLMHGQTWTSPAQGPGYSQGYRGHISTSAGRGRGRGLPY", "length": 1512 }, "evidence": [ { "id": "A0A8V0Z3K4", "url": "https://omabrowser.org/oma/group/A0A8V0Z3K4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F092-1", "protein_name": "Cyclin-dependent kinase 13", "gene_name": "cdk13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPNPEIVGREGRGRSPPPQRSQREARRSKSRRERHRDGKGRSASSSSRRKRHKRGREKQLQQPQPWQQQDALYDGDAGTLVEYDDVSSQSERFSGSPSPRTDALSVDRLSEAELQDCGYEAPAGREHNSSSRRRDGPAERIRSEKDAKRNRSGREQDAAFKSRSGVRNHDSNGRKPSSASQADKKESRRHKSKPKPEKDAPSAYREPPQAYRDDREELRAYRRSSPSFKATADNASPYGTSYYGYQSPPANYQLIPWRSPKKQSPTSTYYRDPEMYAAYNALNSSGKRKRSPASPYWRRSPSYGRHSPYEQGEFAGSPYGQRRRSRSPTPDTRRPVKSGSRSPYPSARHSRSRSRHRVSRSRSRPSSLSPSSLTLKSSLAAELSKQKKAKAAEAARAKNSSSNASTPTKGSSSSSNAPQPSPVTNHAAKKTRPPSPPPPEKGPRTPVCSQPQSPVERPAKRSADVPLPGRDAKLKEEKKKQAVKEKEKTVAPVVATHTPAANNMEHLEANDSVSSLKESSAGKKSSKPERKVRALLSDLPLPPELPGLTPASPLSPPDEKKTPAPRRRPKICGPRFGEIKETEIDWGKRCVDKFEIIGITGEGTYGQVYKAKDKDTAELVALKKVRLDNEKEGFPITAIREIKILRQLNHKSIINMKEIVTDKEDALDFKNDKGAFYLVFEYMDHDLMGLLESGLVHFNESHIKSFMRQLLEGLDYCHKKNFLHRDIKCSNILLNNKGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFAFIPLMALDLFDHMLALDPSKRCTAEQALNSDFLRDVDPAKMPPPDLPLWQDCHELWSKKRRRQKQMPEELTAPKAPRKELGLDDSRSNTPQGFGTAAGGHKPQGSANAAGLLDPKSANSQLTQDQLAVLLNLLQSKSSAAGGSAQFMQTVSSKMNPETLQQLSKALPCGLPESERPPEPPALPKTSKALPAAASGPGAPRTPPMPKPPSPPGPQQADGESSASATQTAVTMLLAQLLNVQQGAPGDGTGFDGADGGVPNTAPAPPEIRQPPEPSPVSPDAEGGGVPSSGTLDSLSILPPDQRPPEPPEPPPCADLDYRHAPESRPAEPPRPPEPDYPPDGSGYGGDFGRPPPPFPHAGFSDSYLGRMMGAGLPPHAPLGPEAFARGDHGMVFSGDQDHRFEYNHGPPPPPPGQPWTSPSQSLGYAAALRGRGLPF", "length": 1289 }, "evidence": [ { "id": "A0A8V0Z3K4", "url": "https://omabrowser.org/oma/group/A0A8V0Z3K4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M1X9-1", "protein_name": "Cyclin-dependent kinase 13", "gene_name": "Cdk13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLFLAAPGAAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRPGGRQKRRRGPRAGQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGNGGSPASSSGTQRRAEGSERRPRRDRRSSSGRSKERHREHRRRDGTRSGSEASKARSRHGHSGEERAEAAKSGSSSSSGGRRKSASATSSSSSSRKDRDLKAHRSRTKSSKEPPSAYKEPPKAYREDKSEPKAYRRRQRSLSPLGGRDESPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSAKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKAAEAAAKAAKASSVSTPTKGNTETGASVSQTNHVKEVKKLKTEHAPSPSSGGTVKSDKTKTKPPLQVTKVDNNLIVEKATKKTVVGKESKPAATKEEPVSTKEKTKPLTPSVGAKEKEQHVALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKKTATQLHSKRRPKICGPRYGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQKQMGMTDDLSTIKAPRKDLSLGLDDSRTSTPQGVLPPAQLKSQNSSSGAPVITGPGQPLNHSELAILLNLLQSKSSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATGEKQTDPSTPQQESSKSLGGVQPSQSIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSKQKDAMLEERENGSGHDAPVQLRPPPEPSTPASGQDDLIQHQDRRILELTPEPERPRILPPDQRPPEPPEPPPVTEEDLDYRTENQHGPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKREGGIDYSTGDTYVPSSDYKDNFGASFSAAPYVSSDGLGSSSAAAPLEARSFIGNSDIQSLDNYSTASSHTGGPPQTSAFTESFPSSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPITVLTNSSDPSTGPESTHPLPAKIHNYNYGGNLQENPGGPSLMHGQTWTSPAQGPGYSQGYRGHISTSAGRGRGRGLPY", "length": 1511 }, "evidence": [ { "id": "A0A8V0Z3K4", "url": "https://omabrowser.org/oma/group/A0A8V0Z3K4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q69ZA1-1", "protein_name": "Cyclin-dependent kinase 13", "gene_name": "Cdk13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLFLAAPGAAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRPGGRQKRRRGPRAGQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGNGGSPASSSGTQRRAEGSERRPRRDRRSSSGRSKERHREHRRRDGTRSGSEASKARSRHGHSGEERAEAAKSGSSSSSGGRRKSASATSSSSSSRKDRDLKAHRSRTKSSKEPPSAYKEPPKAYREDKSEPKAYRRRQRSLSPLGGRDESPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSAKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKAAEAAAKAAKASNASTPTKGNTETGASVSQTNHVKEVKKLKTEHAPSPSSGGTVKSDKAKTKPPLQVTKVDNNLTVEKATKKTVVGKESKPAATKEEPVSTKEKSKPLTPSTGAKEKEQHVALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKKTAAQLHSKRRPKICGPRYGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQKQMGMTDDLSTIKAPRKDLSLGLDDSRTNTPQGVLPPAQLKSQSNSNVAPVITGPGQPLNHSELAILLNLLQSKSSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATGEKQTDPSTPQQESSKSLGGVQPSQTIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSKQKDAMLEERENGSGHEAPLQLRPPLEPSTPGSGQDDLIQHQDRRILELTPEPDRPRILPPDQRPPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKREGGIDYPTGDTYVPSSDYKDNFGSSFSAAPYVSSDGLGSSSAAAPLEARSFIGNSDIQSLDNYSTASSHTGGPPQTSAFTESFASSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPITVLTNSNDPSTGPESTHPLPAKMHNYNYGGNLQENPGGPSLMHGQTWTSPAQGPGYSQGYRGHISTSAGRGRGRGLPY", 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"https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "pmid": "" }, { "name": "RNA polymerase II CTD heptapeptide repeat kinase activity", "id": "GO:0008353", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008353", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "pmid": "" }, { "name": "cyclin binding", "id": "GO:0030332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030332", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "pmid": "" }, { "name": "cyclin K-CDK13 complex", "id": "GO:0002945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002945", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "pmid": "" }, { "name": "cyclin/CDK positive transcription elongation factor complex", "id": "GO:0008024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008024", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "pmid": "" }, { "name": "positive regulation of transcription elongation by RNA polymerase II", "id": "GO:0032968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032968", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "pmid": "" }, { "name": "alternative mRNA splicing, via spliceosome", "id": "GO:0000380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000380", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1054, "end_pos": 1056, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1199, "end_pos": 1201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1259, "end_pos": 1261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1303, "end_pos": 1305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1397, "end_pos": 1399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1477, "end_pos": 1479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10216", "name": "", "equation": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0XNJ2-1", "A0A8V0Y2I5-1", "Q5ZKN1-1", "A0A8V0YIV6-1", "P13863-1", "E1BUG0-1", "A0A8V0ZD40-1" ], "evidence": [ { "id": "10216", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10216" } ] }, { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", "A0A8V0YKK3-1", "A0A1D5NWT4-1", "A0A1D5PMQ7-1", "E1BWA3-1", "F1NVF2-1", "A0A1D5PXN4-1", "A0A3Q2TY19-1", "A0A3Q2U592-1", "A0A8V0XCV5-1", "A0A1D5P8A9-1", "A0A1D5PMG2-1", 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"A0A8V0Y3D1-1", "A0A8V0Y7C3-1", "A0A8V0YCY4-1", "A0A8V0YIV6-1", "A0A8V0YK18-1", "A0A8V0YM22-1", "A0A8V0YTN5-1", "A0A8V0YTP2-1", "Q5F3L1-1", "A0A8V0XU96-1", "E1C6T4-1", "A0A8V0Y3L2-1", "A0A8V0YCY8-1", "A0A8V0Y9Q1-1", "A0A8V0ZD48-1", "A0A8V0ZD60-1", "A0A8V0ZBZ2-1", "A0A8V0Z9J0-1", "A0A8V1ABF3-1", "Q8AYC9-1", "A0A8V0Z927-1", "A0A8V1A2T9-1", "Q5ZKI0-1", "Q7T0B1-1", "P10741-1", "A0A8V1AMK5-1", "P67962-1", "A0A8V0YFH4-1", "E1C848-1", "A0A8V0X8M1-1", "E1BW33-1", "A0A8V0Z283-1", "A0A8V0Z157-1", "A0A3Q2U4X3-1", "A0A8V0XW11-1", "E1BUG0-1", "A0A8V1ABP4-1", "A0A8V1AJA4-1", "A0A8V1AEH4-1", "F1NJH1-1", "A0A3Q2TRY2-1", "A0A8V0X3D6-1", "A0A1D5PD64-1", "A0A8V0XQ97-1", "R4GJB8-1", "A0A8V0X5Z8-1", "A0A8V0XG21-1", "A0A8V0XB58-1", "A0A8V0XMX8-1", "A0A8V0XQS0-1", "A0A8V0XW29-1", "A0A8V0Y074-1", "A0A8V0XXB8-1", "A0A8V0XQ14-1", "A0A8V0XI18-1", "A0A8V0XMT1-1", "A0A8V0Y457-1", "A0A8V0Y823-1", "A0A8V0Y4L8-1", "A0A8V0XND6-1", "A0A8V0Y8X9-1", "A0A8V0YZ74-1", "A0A8V0YTI1-1", "A0A8V0YLV1-1", "A0A8V0Z2E3-1", "A0A8V0YCV9-1", "A0A8V0YSH3-1", "A0A8V0YYX2-1", "A0A8V0YZY4-1", "Q5ZIU3-1", "A0A8V0YZK0-1", "A0A8V0ZKM9-1", "A0A8V0ZWC7-1", "A0A8V1A1Y7-1", "A0A8V1A069-1", "A0A8V0ZI32-1", "A0A8V0ZH91-1", "E1BQV7-1", "A0A8V0ZRX1-1", "A0A8V0ZUU9-1", "A0A8V1A0Y8-1", "A0A8V1A7E9-1", "A0A8V1A7E0-1", "A0A8V1A3T8-1", "A0A8V1A9S5-1", "A0A8V1A7M0-1", "A0A8V1A675-1", "A0A8V1A1P3-1", "A0A8V1ADT4-1", "E1BWT0-1", "A0A8V1ACF6-1", "A0A8V1ADN9-1", "A0A8V1AM12-1", "A0A8V1A4Q4-1", "Q90891-1", "F1NUX4-1", "A0A8V0ZZE4-1", "P05625-1", "P13863-1", "Q04982-2", "Q0GGW5-1", "Q6XUX0-1", "Q8QGX4-1", "Q9I9E0-1", "Q9IA88-1", "Q5ZJK4-1", "A0A1D5PTJ8-1", "E1C2I2-1", "F1NCX7-1", "F1NKW3-1", "A0A8V1A0W4-1", "A0A8V1A4J8-1", "A0A8V1ACK0-1", "F1NCY7-1", "A0A8V0X6T4-1", "A0A8V0XUM6-1", "A0A8V0XEA3-1", "A0A8V0YHH2-1", "A0A3Q2UI52-1", "A0A8V0ZZK5-1", "A0A8V0ZPX2-1", "A0A8V1ACB5-1", "A0A8V0YDH4-1", "A0A8V1AFS4-1", "A0A8V1AH12-1", "A0A8V0ZQT5-1", "A0A8V0ZFP1-1", "E1C764-1", "F1P4G3-1", "A0A8V0Y2I5-1", "A0A8V0ZLU3-1", "A0A8V0ZNP7-1", "A0A8V0Z2Z3-1", "A0A8V0YNI5-1", "Q90771-1", "A0A8V0X4P0-1", "A0A8V0X7R2-1", "A0A3Q3A664-1", "A0A8V0YGW2-1", "E1C581-1", "A0A8V1AC40-1", "A0A3Q2TUS7-1", "A0A1D5PA08-1", "A0A8V0XFW1-1", "A0A8V0XAH9-1", "A0A8V0ZFM2-1", "A0A8V1A4A1-1", "A0A8V0ZD40-1", "A0A8V0Z6T1-1", "A0A8V1A4V7-1", "A0A8V0YZF2-1", "E1BX69-1", "A0A8V0Y955-1", "A0A1D5PB73-1", "A0A1D5PV76-1", "A0A1D5PX90-1", "A0A1L1RWI9-1", "A0A3Q2TV19-1", "A0A3Q2UF44-1", "A0A8V0X4Q3-1", "A0A8V0Z124-1", "A0A8V0Z6K4-1", "A0A8V1AIY7-1", "A0A8V1AE45-1", "A0A8V0YZV9-1", "A0A8V0YYZ3-1", "A0A8V0ZUC6-1", "A0A8V0ZUU8-1", "A0A8V1AG70-1", "F1NA68-1", "F1NLR7-1", "A0A8V0Y6K1-1", "A0A8V0XS42-1", "A0A8V0YRN4-1", "A0A8V0YFP8-1", "A0A8V1A7P9-1", "A0A1D5PRN8-1", "A0A3Q3AAD7-1", "A0A3Q2TWZ8-1", "A0A8V0XBZ0-1", "A0A8V0XFX2-1", "A0A8V0YFL1-1", "A0A8V0YTL9-1", "A0A8V0YMB3-1", "A0A8V0X2Y2-1", "A0A8V0XCY6-1", "A0A3Q2UI62-1", "A0A8V0Y241-1", "A0A8V0Z8G2-1", "A0A8V1ABR8-1", "A0A8V1AP60-1", "A0A8V0YZM1-1", "A0A8V0ZB38-1", "A0A8V0Z466-1", "A0A8V0ZA06-1", "A0A8V1AMQ2-1", "A0A8V0ZGY3-1", "A0A8V0ZQJ2-1", "A0A8V0ZYU6-1", "A0A8V1A513-1", "A0A8V0XE48-1", "A0A8V0XKG0-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NWT4", "gene_name": "RPS6KA3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5NWT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NWT4" } ] } ] }, { "uniprot_ac": "A0A1D5P0M9", "gene_name": "MAP3K13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5P0M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P0M9" } ] } ] }, { "uniprot_ac": "A0A1D5P517", "gene_name": "PLK3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A1D5P517", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P517" } ] } ] }, { "uniprot_ac": "A0A1D5P8A9", "gene_name": "SNRK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5P8A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P8A9" } ] } ] }, { "uniprot_ac": "A0A1D5PA08", "gene_name": "STK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PA08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PA08" } ] } ] }, { "uniprot_ac": "A0A1D5PB73", "gene_name": "CASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PB73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PB73" } ] } ] }, { "uniprot_ac": "A0A1D5PD64", "gene_name": "MAP2K3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A1D5PD64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PD64" } ] } ] }, { "uniprot_ac": "A0A1D5PMG2", "gene_name": "DCLK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMG2" } ] } ] }, { "uniprot_ac": "A0A1D5PMQ7", "gene_name": "STK40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PMQ7" } ] } ] }, { "uniprot_ac": "A0A1D5PRN8", "gene_name": "DAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PRN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PRN8" } ] } ] }, { "uniprot_ac": "A0A1D5PTJ8", "gene_name": "MAP3K5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A1D5PTJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PTJ8" } ] } ] }, { "uniprot_ac": "A0A1D5PUY5", "gene_name": "PRKCB", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A1D5PUY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PUY5" } ] } ] }, { "uniprot_ac": "A0A1D5PV76", "gene_name": "STK17A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PV76" } ] } ] }, { "uniprot_ac": "A0A1D5PX90", "gene_name": "KSR2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A1D5PX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PX90" } ] } ] }, { "uniprot_ac": "A0A1D5PXN4", "gene_name": "PRKCD", "activity": [ { "ec_number": "2.7.11.13", "activity": 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"A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XFX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XFX2" } ] } ] }, { "uniprot_ac": "A0A8V0XG21", "gene_name": "LOC107050335", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XG21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XG21" } ] } ] }, { "uniprot_ac": "A0A8V0XI18", "gene_name": "ATM", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XI18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XI18" } ] } ] }, { "uniprot_ac": "A0A8V0XKG0", "gene_name": "NEK9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8V0XKG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XKG0" } ] } ] }, { "uniprot_ac": "A0A8V0XLV6", "gene_name": "MAPK10", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XLV6" } ] } ] }, { "uniprot_ac": "A0A8V0XMT1", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMT1" } ] } ] }, { "uniprot_ac": "A0A8V0XMX8", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] } ] }, { "uniprot_ac": "A0A8V0Y2I5", "gene_name": "CDK7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y4L8", "database": 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] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y7C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y7C3" } ] } ] }, { "uniprot_ac": "A0A8V0Y823", "gene_name": "SRPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y823" } ] } ] }, { "uniprot_ac": "A0A8V0Y8X9", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] } ] }, { "uniprot_ac": "A0A8V0Y9Q1", "gene_name": "LOC107055388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y9Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y9Q1" } ] } ] }, { "uniprot_ac": "A0A8V0YCV9", "gene_name": "SIK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YCV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YCV9" } ] } ] }, { 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] } ] }, { "uniprot_ac": "A0A8V0YRN4", "gene_name": "GAK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YRN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRN4" } ] } ] }, { "uniprot_ac": "A0A8V0YSH3", "gene_name": "RPS6KA6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] } ] }, { "uniprot_ac": "A0A8V0YXZ5", "gene_name": "CDC42BPA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YXZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YXZ5" } ] } ] }, { "uniprot_ac": "A0A8V0YYX2", "gene_name": "PAK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYX2" } ] } ] }, { "uniprot_ac": "A0A8V0YYZ3", "gene_name": "SPEG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YYZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YYZ3" } ] } ] }, { "uniprot_ac": "A0A8V0YZ74", "gene_name": "MAP2K5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0YZ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZ74" } ] } ] }, { "uniprot_ac": "A0A8V0YZF2", "gene_name": "PAK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZF2" } ] } ] }, { "uniprot_ac": "A0A8V0YZK0", "gene_name": "MAP3K6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0YZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZK0" } ] } ] }, { "uniprot_ac": "A0A8V0YZM1", "gene_name": "MOK", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0YZM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZM1" } ] } ] }, { "uniprot_ac": "A0A8V0YZV9", "gene_name": "ATR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZV9" } ] } ] }, { "uniprot_ac": "A0A8V0YZY4", "gene_name": "SBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YZY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YZY4" } ] } ] }, { "uniprot_ac": "A0A8V0Z124", "gene_name": "VRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z124", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z124" } ] } ] }, { "uniprot_ac": "A0A8V0Z157", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z157" } ] } ] }, { "uniprot_ac": "A0A8V0Z1X0", "gene_name": "MAP4K3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z1X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z1X0" } ] } ] }, { "uniprot_ac": "A0A8V0Z283", "gene_name": "MARK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z283" } ] } ] }, { "uniprot_ac": "A0A8V0Z2E3", "gene_name": "PDIK1L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z2E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z2E3" } ] } ] }, { "uniprot_ac": "A0A8V0Z2Z3", "gene_name": "AAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z2Z3", "database": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z807", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z807" } ] } ] }, { "uniprot_ac": "A0A8V0Z8G2", "gene_name": "TTBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8G2" } ] } ] }, { "uniprot_ac": "A0A8V0Z8T4", "gene_name": "RPS6KC1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z8T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z8T4" } ] } ] }, { "uniprot_ac": "A0A8V0Z927", "gene_name": "PINK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Z927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z927" } ] } ] }, { "uniprot_ac": "A0A8V0Z930", "gene_name": "CAMK2B", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z930" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0Z930", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0ZA45", "gene_name": "MAP4K5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZA45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZA45" } ] } ] }, { "uniprot_ac": "A0A8V0ZB33", "gene_name": "CAMK2G", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V0ZB33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB33" } ] } ] }, { "uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", 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"A0A8V0Z3K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9D9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z9D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z9D9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELPAVSLKAIILVHWLLTVWGCMNVSFPVSYAWGNFTVLAVGIWAIVQRDSLDAIMMFLTGLLLTVLTDIIHISVYYPLHGYLTGAKRFGVGMAIFSLLLKPGSCYFVYRMYRERGGEYIFNIDLESSSDSHFAYNGIEATAVTLTQLTQVFPLFHFLYFVHFLGALGCPSHFANLFLLWESKGIVPSTWIMHVRKGWISNFVLHVLAILIVLDCYFLTWEMGLMFILCSFAWRHSLFLLAVVAGNTVAALPERVVRAGYSVSFFSKHSWC", "length": 272, "header": "tr|A0A8V0Z3K7-1|A0A8V0Z3K7_CHICK Isoform 1 of Angiotensin II receptor associated protein OS=Gallus gallus OX=9031 GN=AGTRAP PE=4 SV=1 CANONICAL=A0A8V0Z3K7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K7/entry#A0A8V0Z3K7-1", "sequence": { "sequence": "MELPAVSLKAIILVHWLLTVWGCMNVSFPVSYAWGNFTVLAVGIWAIVQRDSLDAIMMFLTGLLLTVLTDIIHISVYYPLHGYLTGAKRFGVGMAIFSLLLKPGSCYFVYRMYRERGGEYIFNIDLESSSDSHFAYNGIEATAVTLTQLTQVFPLFHFLYFVHFLGALGCPSHFANLFLLWESKGIVPSTWIMHVRKGWISNFVLHVLAILIVLDCYFLTWEMGLMFILCSFAWRHSLFLLAVVAGNTVAALPERVVRAGYSVSFFSKHSWC", "length": 272, "header": "tr|A0A8V0Z3K7-1|A0A8V0Z3K7_CHICK Isoform 1 of Angiotensin II receptor associated protein OS=Gallus gallus OX=9031 GN=AGTRAP PE=4 SV=1 CANONICAL=A0A8V0Z3K7-1" }, "locus": { "chromosome": "21", "start_pos": 5633218, "end_pos": 5627335, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042572.1", "url": "https://www.ensembl.org/id/ENSGALT00010042572.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025062.1", "url": "https://www.ensembl.org/id/ENSGALP00010025062.1" } ] } }, { "isoform_ac": "A0A8V0Z9D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K7/entry#A0A8V0Z9D9-1", "sequence": { "sequence": "MELPAVSLKAIILVHWLLTVWGCMNVSFPVSYAWGNFTVLAVGIWAIVQRDSLDAIMMFLTGLLLTVLTDIIHISVYYPLHGYLTGAKRFGVGMAIFSLLLKPGSCYFVYRMYRERGGEYIFNIDLESSSDSHFAYNGIEATAVTLTQLTQVSTVQARTAVPMRQLISRKPLHCGLTQARQLSIHIEALVCSRMDTSLPQSSLTLLPCLF", "length": 210, "header": "tr|A0A8V0Z9D9-1|A0A8V0Z3K7_CHICK Computationally mapped isoform of Angiotensin II receptor associated protein OS=Gallus gallus OX=9031 GN=AGTRAP PE=4 SV=1 CANONICAL=A0A8V0Z3K7-1" }, "locus": { "chromosome": "21", "start_pos": 5633218, "end_pos": 5626299, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042575.1", "url": "https://www.ensembl.org/id/ENSGALT00010042575.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025065.1", "url": "https://www.ensembl.org/id/ENSGALP00010025065.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of blood pressure", "id": "GO:0008217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008217", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K7" } ], "pmid": "" }, { "name": "angiotensin-activated signaling pathway", "id": "GO:0038166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038166", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z569-1", "uniprot_ac": "A0A8V0Z569", "uniprot_id": "A0A8V0Z569_CHICK", "mass": { "chemical_mass": 66582.0, "monoisotopic_mass": 66582.0 }, "refseq": {}, "gene_names": [ { "name": "KCNK10", "type": "recommended", "evidence": [ { "id": "A0A8V0Z569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569" } ] } ], "protein_names": [ { "name": "Potassium two pore domain channel subfamily K member 10", "type": "synonym", "evidence": [ { "id": "A0A8V0Z569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z569", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KCNK10", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569", "locus": { "chromosome": "5", "start_pos": 42490471, "end_pos": 42555890, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017881", "url": "https://www.ensembl.org/id/ENSGALG00010017881" } ] } } ], "crossref": [ { "id": "A0A8V0Z569", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z569", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000010598", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000010598", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "428902", "url": "https://www.ncbi.nlm.nih.gov/gene/428902", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:428902", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428902", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MNWYKPL", "url": "https://omabrowser.org/oma/group/MNWYKPL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3K9", "url": "https://www.orthodb.org/?gene=A0A8V0Z3K9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z569", "url": "https://www.orthodb.org/?gene=A0A8V0Z569", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NUZ5", "url": "https://www.orthodb.org/?gene=F1NUZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11003:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11003:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-1299503", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1299503", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5576886", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576886", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78547", "url": "https://www.rhea-db.org/rhea/78547", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "78555", "url": "https://www.rhea-db.org/rhea/78555", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z3K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3K9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z569", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z569-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NUZ5", "url": "https://www.uniprot.org/uniprotkb/F1NUZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NUZ5-1", "url": "https://www.uniprot.org/uniprotkb/F1NUZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQVCCFPCCQQDCREMRDKNRCVYLEEGSVEERSEKRKQNRGNKIRTALQQCAISLQHKTNLSQVLIWTWQLLAVPSPVPACEPEPKTNGHYASPRLSVSSRAMVVATMEAPSQGLQTVMKWKTVVAIFVVVVVYLVAGGLVFRALEQPFESRQKNTIALEKADFLREHVCVTQLELETLIQHAIDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTVGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKHIEGWTALESIYFVVVTLTTVGFGDFVAGGNADIHYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFTALETGRFKASSQESINNRPNNLRLKGSDQLHKHGQGASEDNIINKFGSSAKMTKRKNKDLKKTIPEDVRKIYETFRNYSLDEEKKEEETEKMCNSENSSSTAVLTNCIQQHSDLENGVIPTETKEREHENKALLEDRN", "length": 592, "header": "tr|A0A8V0Z569-1|A0A8V0Z569_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 10 OS=Gallus gallus OX=9031 GN=KCNK10 PE=3 SV=1 CANONICAL=A0A8V0Z569-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569/entry#A0A8V0Z3K9-1", "sequence": { "sequence": "MKLTYCDTLTVAVPSPVPACEPEPKTNGHYASPRLSVSSRAMVVATMEAPSQGLQTVMKWKTVVAIFVVVVVYLVAGGLVFRALEQPFESRQKNTIALEKADFLREHVCVTQLELETLIQHAIDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTVGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKHIEGWTALESIYFVVVTLTTVGFGDFVAGGNADIHYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFTALETGRFKASSQESINNRPNNLRLKGSDQLHKHGQGASEDNIINKFGSSAKMTKRKNKDLKKTIPEDVRKIYETFRNYSLDEEKKEEETEKMCNSENSSSTAVLTNCIQQHSDLENGVIPTETKEREHENKALLEDRN", "length": 530, "header": "tr|A0A8V0Z3K9-1|A0A8V0Z569_CHICK Computationally mapped isoform of Potassium two pore domain channel subfamily K member 10 OS=Gallus gallus OX=9031 GN=KCNK10 PE=3 SV=1 CANONICAL=A0A8V0Z569-1" }, "locus": { "chromosome": "5", "start_pos": 42554780, "end_pos": 42491659, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043231.1", "url": "https://www.ensembl.org/id/ENSGALT00010043231.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025685.1", "url": "https://www.ensembl.org/id/ENSGALP00010025685.1" } ] } }, { "isoform_ac": "A0A8V0Z569-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569/entry#A0A8V0Z569-1", "sequence": { "sequence": "MQVCCFPCCQQDCREMRDKNRCVYLEEGSVEERSEKRKQNRGNKIRTALQQCAISLQHKTNLSQVLIWTWQLLAVPSPVPACEPEPKTNGHYASPRLSVSSRAMVVATMEAPSQGLQTVMKWKTVVAIFVVVVVYLVAGGLVFRALEQPFESRQKNTIALEKADFLREHVCVTQLELETLIQHAIDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTVGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKHIEGWTALESIYFVVVTLTTVGFGDFVAGGNADIHYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFTALETGRFKASSQESINNRPNNLRLKGSDQLHKHGQGASEDNIINKFGSSAKMTKRKNKDLKKTIPEDVRKIYETFRNYSLDEEKKEEETEKMCNSENSSSTAVLTNCIQQHSDLENGVIPTETKEREHENKALLEDRN", "length": 592, "header": "tr|A0A8V0Z569-1|A0A8V0Z569_CHICK Isoform 1 of Potassium two pore domain channel subfamily K member 10 OS=Gallus gallus OX=9031 GN=KCNK10 PE=3 SV=1 CANONICAL=A0A8V0Z569-1" }, "locus": { "chromosome": "5", "start_pos": 42534731, "end_pos": 42491659, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043225.1", "url": "https://www.ensembl.org/id/ENSGALT00010043225.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025681.1", "url": "https://www.ensembl.org/id/ENSGALP00010025681.1" } ] } }, { "isoform_ac": "F1NUZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569/entry#F1NUZ5-1", "sequence": { "sequence": "MKFPIETPRKQVNWDPQVAVPSPVPACEPEPKTNGHYASPRLSVSSRAMVVATMEAPSQGLQTVMKWKTVVAIFVVVVVYLVAGGLVFRALEQPFESRQKNTIALEKADFLREHVCVTQLELETLIQHAIDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTVGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKHIEGWTALESIYFVVVTLTTVGFGDFVAGGNADIHYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFTALETGRFKASSQESINNRPNNLRLKGSDQLHKHGQGASEDNIINKFGSSAKMTKRKNKDLKKTIPEDVRKIYETFRNYSLDEEKKEEETEKMCNSENSSSTAVLTNCIQQHSDLENGVIPTETKEREHENKALLEDRN", "length": 537, "header": "tr|F1NUZ5-1|A0A8V0Z569_CHICK Computationally mapped isoform of Potassium two pore domain channel subfamily K member 10 OS=Gallus gallus OX=9031 GN=KCNK10 PE=3 SV=3 CANONICAL=A0A8V0Z569-1" }, "locus": { "chromosome": "5", "start_pos": 42545190, "end_pos": 42491659, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043229.1", "url": "https://www.ensembl.org/id/ENSGALT00010043229.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025684.1", "url": "https://www.ensembl.org/id/ENSGALP00010025684.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:428902", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:428902", "resource": "KEGG Pathway" }, { "id": "R-GGA-1299503", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-1299503", "resource": "Reactome", "description": "TWIK related potassium channel (TREK)" }, { "id": "R-GGA-5576886", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5576886", "resource": "Reactome", "description": "Phase 4 - resting membrane potential" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LY37-1", "protein_name": "Potassium channel subfamily K member 10", "gene_name": "Kcnk10", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKFPIETPRKQVNWDPKVAVPAATPPVCQPKSATNGHHPVPRLSISSRATVVARMEGASQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHICVSPQELETLIQHALDADNAGVSPVGNSSNSSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGSEQLNKHGQGASEDNIINKFGSTSKLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEKMCNSDNSSTAMLTECIQQQAEMENGIIPTDTKDQGLENNSLLEDRN", "length": 538 }, "evidence": [ { "id": "A0A8V0Z569", "url": "https://omabrowser.org/oma/group/A0A8V0Z569/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8M2BH55-1", "protein_name": "Potassium channel subfamily K member 10b isoform X1", "gene_name": "kcnk10b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKFPLENPRKQVNWDPEQVAVQTNMVPQKKPQSGAVQSSLVQASVSAMQNPMGCELKNGHCLLPRLSISSRSASVLTGMDSGADGSALHSVMKWKTVLAVFVVVLSYLVCGGLAFQALEQPFESIQKDSITQKKAQFLQKNPCVSHADLEALIKHAVEAVSTGVSPIGDASYNSSQWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGVGDQLGTMFMKSILRVEKVFRQKHKQISQTKIRVTSTILFIIAGCIVFVTIPAVFFKHTEGWSTLDAIYFVVITLTTIGIGDYVAGGDRKIEYMKWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGQQVGGIKAHAVEWKANVRAELRETRRRLSGEIHDKLQRAATIRSMERRRLGLEQRAHSLDMLSPEKRAVFASLDAGRFKTSSQESIDTKLNNLRLKAKCGEQQTSSEENIFNRFGSLTKLAKRNRSKDLRRNIQEDPTQIDELDNVTLGEERQEEEDEDQMEEEEEEKVEKQANTGFTCLPHYPEEPKQQNGLAPAQVKEQERNKRLELKEHQP", "length": 575 }, "evidence": [ { "id": "A0A8V0Z569", "url": "https://omabrowser.org/oma/group/A0A8V0Z569/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9TY49-1", "protein_name": "Potassium two pore domain channel subfamily K member 10", "gene_name": "KCNK10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKFPIETPRKQVNWDPKVAVPAAAPPACPPKAAANGAPPAPRLAVSSRAAVVARMEGAAQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHICVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCVVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFAALDAGRCKASSQESIDHRPNNLRLQASEPLQKRGQGASEDNIVNKLGSASRLTKRKNRDLRKALPEDVHRIYRTLRHYSLDEEKKEDTEKGCNSDHSSTAVLTDCAQPPAGAGDGVGPADAKDAERDSSALLEARN", "length": 537 }, "evidence": [ { "id": "A0A8V0Z569", "url": "https://omabrowser.org/oma/group/A0A8V0Z569/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P57789-1", "protein_name": "Potassium channel subfamily K member 10", "gene_name": "KCNK10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFFLYTDFFLSLVAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVARMEGTSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEKMCNSDNSSTAMLTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN", "length": 538 }, "evidence": [ { "id": "A0A8V0Z569", "url": "https://omabrowser.org/oma/group/A0A8V0Z569/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BUW1-1", "protein_name": "Potassium channel subfamily K member 10", "gene_name": "Kcnk10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYFSYIGYFFLPPLVAVPAAAPPVCQPKSATNGHHPVPRLSISSRATVVARMEGASQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHICVSPQELETLIQHALDADNAGVSPVGNSSNSSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLTKHGQGASEDNIINKFGSTSKLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEDETEKMCNSDNSSTAMLTECIQQQAEMENGMVPTDTKDQGLENNSLLEDRN", "length": 535 }, "evidence": [ { "id": "A0A8V0Z569", "url": "https://omabrowser.org/oma/group/A0A8V0Z569/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JIS4-1", "protein_name": "Potassium channel subfamily K member 10", "gene_name": "Kcnk10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKFPIETPRKQVNWDPKVAVPAAAPPVCQPKSATNGHHPVPRLSISSRATVVARMEGASQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHICVSPQELETLIQHALDADNAGVSPVGNSSNSSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQGASEDNIINKFGSTSKLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEDETEKMCNSDNSSTAMLTECIQQQAEMENGMVPMDTKDQGLENNSLLEDRN", "length": 538 }, "evidence": [ { "id": "A0A8V0Z569", "url": "https://omabrowser.org/oma/group/A0A8V0Z569/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z569", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z569", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569" } ], "pmid": "" }, { "name": "outward rectifier potassium channel activity", "id": "GO:0015271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015271", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z569", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569" } ], "pmid": "" }, { "name": "potassium ion leak channel activity", "id": "GO:0022841", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022841", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z569", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569" } ], "pmid": "" }, { "name": "mechanosensitive potassium channel activity", "id": "GO:0098782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098782", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z569", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z569", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569" } ], "pmid": "" }, { "name": "cellular response to arachidonate", "id": "GO:1904551", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904551", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z569", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": "78547", "name": "", "equation": "Rb(+)(in) = Rb(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78547", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78547" } ] }, { "id": "78555", "name": "", "equation": "Cs(+)(in) = Cs(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "78555", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/78555" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z569", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z569" }, { "id": "PF07885", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 258, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 399, "end_pos": 401 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 551, "end_pos": 553 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3L3-1", "uniprot_ac": "A0A8V0Z3L3", "uniprot_id": "A0A8V0Z3L3_CHICK", "mass": { "chemical_mass": 34406.0, "monoisotopic_mass": 34406.0 }, "refseq": { "ac": "XP_015141514", "name": "DDRGK domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141514" }, "gene_names": [ { "name": "DDRGK1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ] }, { "name": "DDRGK1", "type": "synonym", "evidence": [ { "id": "XP_015141514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141514" } ] } ], "protein_names": [ { "name": "DDRGK domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3/entry#names_and_taxonomy" } ] }, { "name": "DDRGK domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_015141514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141514" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015141514.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015141514", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141514" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DDRGK1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3", "locus": { "chromosome": "4", "start_pos": 88333436, "end_pos": 88363583, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017886", "url": "https://www.ensembl.org/id/ENSGALG00010017886" } ] } } ], "crossref": [ { "id": "A0A8V0Z3L3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3L3", "database": "AlphaFoldDB", "categories": [] }, { "id": "422941", "url": "https://www.ncbi.nlm.nih.gov/gene/422941", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:422941", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422941", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EFTRECN", "url": "https://omabrowser.org/oma/group/EFTRECN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3L3", "url": "https://www.orthodb.org/?gene=A0A8V0Z3L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48176:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48176:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09756", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09756", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015141514", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015141514", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAVLLAVVAALLAVLLFFATLFRRSAPAADEEHQQDVAAAVRPRPYVEERGDGMPRRRRNLGNRMMAQRRAQQAEEWVEEEDDAEEVPELQVTGKIGAKKQRKLEEKQARKAQREAEEAEREERRKLESKREEERRKEEERIRLEEERQEEEKRKAKEEEEKREYEEYLKLKESFVVEEEGVEESMTEEETRSFLKEFIEYIKKTKVIQLEDLASHMGLRTQDAINRIQDLMADGTLTGVIDDRGKFIYITPEEMAAVAQFIKQRGRVSIAELVQASNSLINLQPDSQAVAPTMA", "length": 296, "header": "tr|A0A8V0Z3L3-1|A0A8V0Z3L3_CHICK Isoform 1 of DDRGK domain-containing protein 1 OS=Gallus gallus OX=9031 GN=DDRGK1 PE=1 SV=1 CANONICAL=A0A8V0Z3L3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3/entry#A0A8V0Z3L3-1", "sequence": { "sequence": "MDAVLLAVVAALLAVLLFFATLFRRSAPAADEEHQQDVAAAVRPRPYVEERGDGMPRRRRNLGNRMMAQRRAQQAEEWVEEEDDAEEVPELQVTGKIGAKKQRKLEEKQARKAQREAEEAEREERRKLESKREEERRKEEERIRLEEERQEEEKRKAKEEEEKREYEEYLKLKESFVVEEEGVEESMTEEETRSFLKEFIEYIKKTKVIQLEDLASHMGLRTQDAINRIQDLMADGTLTGVIDDRGKFIYITPEEMAAVAQFIKQRGRVSIAELVQASNSLINLQPDSQAVAPTMA", "length": 296, "header": "tr|A0A8V0Z3L3-1|A0A8V0Z3L3_CHICK Isoform 1 of DDRGK domain-containing protein 1 OS=Gallus gallus OX=9031 GN=DDRGK1 PE=1 SV=1 CANONICAL=A0A8V0Z3L3-1" }, "locus": { "chromosome": "4", "start_pos": 88363530, "end_pos": 88334592, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043236.1", "url": "https://www.ensembl.org/id/ENSGALT00010043236.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025690.1", "url": "https://www.ensembl.org/id/ENSGALP00010025690.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:422941", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:422941", "resource": "KEGG Pathway" }, { "id": "R-GGA-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SK08-1", "protein_name": "DDRGK domain-containing protein 1", "gene_name": "DDRGK1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRWLQQTLSLPLKNTHVCMHPPPCFASLPEGRVSCQAAQEPLHNEEVPAAAGRVARPQPLEPEEQRAAGRPRRRRDLGSRLQAQRRAQRVAWADENEEEAIIQAQEEEDIEKPVETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAQEEQAQREHEEYLKLKETFVVEEEGVGETMTEEQSHSFLAEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQDLLAEGTLTGVIDDRGKFIYITPEELAAVANFIRQRGRVSITELAQASNSLIAWGRETPAQAPA", "length": 319 }, "evidence": [ { "id": "A0A8V0Z3L3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3L3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZAS9-1", "protein_name": "DDRGK domain-containing protein 1", "gene_name": "Ddrgk1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVGGAWRSGSRRRAGVAARLSVVMVGPWVYLVAAVLLIGLILFLTRSRGRAAAADGEPLHNEEERTGAGQVARSWPQESEEQRTGGRPRRRRDLGSRLQAQRRAQRVTWEEVDENEGEAAVPAQEEEGVEKPAEVHPTGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLKEEQKEEEERKAREEQARREHEEYLKLKEAFVVEEEGVSETMTEEQSHSFLTEFINYIKQSKVVLLEDLAFQMGLRTQDAINRIQDLLTEGTLTGVIDDRGKFIYITPEELAAVASFIRQRGRVSITELAQASNSLISWGQDLPAQASV", "length": 339 }, "evidence": [ { "id": "A0A8V0Z3L3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3L3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55CM7-1", "protein_name": "DDRGK domain-containing protein 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGDTYSLVLVAGYLSIFLFIGAIGYFYLSKPRIPSSNVNEQQQQQQQQQQQQQQPQINIEDEPQQRGGIGRMNLRNRRQPIINQRDEDTESSGSDSDNSTNSDNYDDDNGQEGEGEDIGVVAPGIVSNRSGKKIGKKKLEKLKLKDEKRKAREYQEYLREEKKKTDLEKEEALKEKRLEEKENEKLRKEEEERIRIEKERKEDEEYNLLKSQISLQESGITKNEDYDKSLLQLFIKYLKEHKICLLEDIAIEFNIKTNEVIDRIKTLDKQGLISGVIDDRGKFIYITKEEMEAVAKFVNKKGRVNIEQIALESNRLIDFSKKVVDNNDQDPVDTN", "length": 335 }, "evidence": [ { "id": "A0A8V0Z3L3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3L3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q80WW9-1", "protein_name": "DDRGK domain-containing protein 1", "gene_name": "Ddrgk1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGPWVYLVAAVLLIGLILFLTRSRGRAAAADGEPLHNEEERAGAGQVGRSLPQESEEQRTGSRPRRRRDLGSRLQAQRRAQRVAWEDGDENVGQTVIPAQEEEGIEKPAEVHPTGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLKEEQKEEEERKAQEEQARREHEEYLKLKEAFVVEEEGVSETMTEEQSHSFLTEFINYIKKSKVVLLEDLAFQMGLRTQDAINRIQDLLTEGTLTGVIDDRGKFIYITPEELAAVANFIRQRGRVSITELAQASNSLISWGQDLPAQASA", "length": 315 }, "evidence": [ { "id": "A0A8V0Z3L3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3L3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94C53-1", "protein_name": "DDRGK domain-containing protein 1", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEIFALIVSMILIVAVIPLFFWKRRRDARSREEVAEPPQVQPRENVARAGGGRRMRRRPAASGASSSTSNVQENGSGSEDEDEDEAGGTQARASKKKEKKRQEREAQRQAEEATRESRNTKQDWYAEMRRKKDEEREAEELKLEEEEKARQAKEEEAAALEFDKWKGEFSVDAEGTTEEVQGGNQDLLSEFVEYIKKQKCVPLEDLAAEFHLRTQECINRIASLESIGRLSGVMDDRGKYIYISMEEMNAVADYIKRQGRVSISHLASKSNQFIDLEPKVQHQLTEEISGMEEISVS", "length": 298 }, "evidence": [ { "id": "A0A8V0Z3L3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3L3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96HY6-1", "protein_name": "DDRGK domain-containing protein 1", "gene_name": "DDRGK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVAPVWYLVAAALLVGFILFLTRSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQDLLAEGTITGVIDDRGKFIYITPEELAAVANFIRQRGRVSIAELAQASNSLIAWGRESPAQAPA", "length": 314 }, "evidence": [ { "id": "A0A8V0Z3L3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3L3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VDD1-1", "protein_name": "DDRGK domain-containing protein 1", "gene_name": "Ddrgk1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLIILVGIAVALLVVIVTLYLLQKKNAAPETKVAAAPQRGVPQRAQEGVPRRAQIARNQRNRLRQNVPAAPVAAAAGALPAAGDSDHEDEGQVDGDEARVPQGAVLDEKMGAKKRAKMEAKEQKRLQREQELHDREQRKVKEAKEEAERKQQEDLEAEAERKRVDAERLAKEERERKEHEEYLKMKAAFSVEEEGFEEGDADDQDNLLADFIQYIRDNKVVVLEDLAVAFKLKTQQVIDRIQNLQADGTLTGVIDDRGKFIYVSEKELLAVAKFIKQRGRVSIAELAESSNNLINLTPISAGGGEASS", "length": 309 }, "evidence": [ { "id": "A0A8V0Z3L3", "url": "https://omabrowser.org/oma/group/A0A8V0Z3L3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 20, "go_terms": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "positive regulation of gene expression", "id": "GO:0010628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "positive regulation of canonical NF-kappaB signal transduction", "id": "GO:0043123", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043123", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "regulation of protein stability", "id": "GO:0031647", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031647", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032436", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "protein localization to endoplasmic reticulum", "id": "GO:0070972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070972", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "cartilage development", "id": "GO:0051216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051216", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0032435", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032435", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "negative regulation of PERK-mediated unfolded protein response", "id": "GO:1903898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "reticulophagy", "id": "GO:0061709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061709", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "negative regulation of IRE1-mediated unfolded protein response", "id": "GO:1903895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903895", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "positive regulation of protein localization to endoplasmic reticulum", "id": "GO:1905552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905552", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "protein K69-linked ufmylation", "id": "GO:1990592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990592", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "regulation of intracellular estrogen receptor signaling pathway", "id": "GO:0033146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033146", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "positive regulation of reticulophagy", "id": "GO:0140501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140501", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin-like protein ligase binding", "id": "GO:0044389", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044389", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" }, { "name": "UFM1-modified protein reader activity", "id": "GO:0141185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141185", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3L6-1", "uniprot_ac": "A0A8V0Z3L6", "uniprot_id": "A0A8V0Z3L6_CHICK", "mass": { "chemical_mass": 47605.0, "monoisotopic_mass": 47605.0 }, "refseq": { "ac": "NP_001265384", "name": "ubiquitin-associated protein 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265384" }, "gene_names": [ { "name": "UBAP1L", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6" } ] }, { "name": "UBAP1L", "type": "synonym", "evidence": [ { "id": "NP_001265384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265384" } ] } ], "protein_names": [ { "name": "Ubiquitin associated protein 1 like", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-associated protein 1-like", "type": "synonym", "evidence": [ { "id": "NP_001265384", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265384" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000245.1. On Dec 3, 2021 this sequence version replaced NP_001265384.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001265384", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265384" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "UBAP1L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6", "locus": { "chromosome": "10", "start_pos": 17781873, "end_pos": 17773021, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017620", "url": "https://www.ensembl.org/id/ENSGALG00010017620" } ] } } ], "crossref": [ { "id": "A0A8V0Z3L6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3L6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14316", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14316", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "769261", "url": "https://www.ncbi.nlm.nih.gov/gene/769261", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769261", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769261", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KVLYWVE", "url": "https://omabrowser.org/oma/group/KVLYWVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3L6", "url": "https://www.orthodb.org/?gene=A0A8V0Z3L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15960", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15960", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15960:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15960:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21267", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21267", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001265384", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265384", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYLDGVPFRTAMSLEGDSAGESTFIEAPAIDLPDCTDILMSTMHDFSLERKVQYWLEAASQHQTSRQQLHTDAIPTAPPCWLLLVDPTEGKEMVGSRAKEGTVRRSISLSADQGRGRASDTESEAGCSEDDECWEDDEYSSTSWEENDREENILRRRNRHGLQQIRPKTSPGLLEPPSENNYKAASPDLGKQRRSMVLFNNMKNELEAARRKLAALVHPLNRATAESKGTPMPPALPQHSRSNRSLKFGPAVEVSHTGSLVPAPPAAPNASMPPIRKHKPTVPSLSPYSCLPPARPLASRKAKPDSAADLLSALSQEERDLIEPVIALGYPARKAILTLQKTGRQSLGQFLGYLRACDRLLKQGYEEGQVEEAMEMFQYSEKKAAEFLHLLAQFNDMGFQQNEIKEVLLLCGNQRDKALEELVMKRQ", "length": 428, "header": "tr|A0A8V0Z3L6-1|A0A8V0Z3L6_CHICK Isoform 1 of Ubiquitin associated protein 1 like OS=Gallus gallus OX=9031 GN=UBAP1L PE=4 SV=1 CANONICAL=A0A8V0Z3L6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6/entry#A0A8V0Z3L6-1", "sequence": { "sequence": "MSYLDGVPFRTAMSLEGDSAGESTFIEAPAIDLPDCTDILMSTMHDFSLERKVQYWLEAASQHQTSRQQLHTDAIPTAPPCWLLLVDPTEGKEMVGSRAKEGTVRRSISLSADQGRGRASDTESEAGCSEDDECWEDDEYSSTSWEENDREENILRRRNRHGLQQIRPKTSPGLLEPPSENNYKAASPDLGKQRRSMVLFNNMKNELEAARRKLAALVHPLNRATAESKGTPMPPALPQHSRSNRSLKFGPAVEVSHTGSLVPAPPAAPNASMPPIRKHKPTVPSLSPYSCLPPARPLASRKAKPDSAADLLSALSQEERDLIEPVIALGYPARKAILTLQKTGRQSLGQFLGYLRACDRLLKQGYEEGQVEEAMEMFQYSEKKAAEFLHLLAQFNDMGFQQNEIKEVLLLCGNQRDKALEELVMKRQ", "length": 428, "header": "tr|A0A8V0Z3L6-1|A0A8V0Z3L6_CHICK Isoform 1 of Ubiquitin associated protein 1 like OS=Gallus gallus OX=9031 GN=UBAP1L PE=4 SV=1 CANONICAL=A0A8V0Z3L6-1" }, "locus": { "chromosome": "10", "start_pos": 17781154, "end_pos": 17775243, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042582.1", "url": "https://www.ensembl.org/id/ENSGALT00010042582.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025072.1", "url": "https://www.ensembl.org/id/ENSGALP00010025072.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:769261", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769261", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MN11-1", "protein_name": "Ubiquitin associated protein 1 like", "gene_name": "UBAP1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNALDDVPFKVPKGFVIDTEPLPGPDLSIPDCRELLLGSMHDFSLERRTLFWVEAVIRGPCPVQCDAPGAASAPPAWLLLASPEQGLEPVPAAVEHPEAGSQEQPEEEEEEEEDQDEEAASSAAEEEPEPSPQPSSAASPRLGQQRCSLDVLRGVRSELAGAGRRLSEGRLASHPRSLLHRLRHRALSLCPGPAPPLGPAPPPLSAPTTLKLPPRPSTAGAMPPLRSHKPTVASLSPYTCLPPPGRVPQPCAAHRSHPDSADLLSALSQEEQDLIGPVVALGYPLHRAIVALQKTGRQSLSQFLSYLSACDRLLRQGYEEGLVDEAMEMFQFSESQAGEFLRLSEQFSDMGFQQDRIKEVLLVHGNRREQALEELVACAQ", "length": 380 }, "evidence": [ { "id": "A0A8V0Z3L6", "url": "https://omabrowser.org/oma/group/A0A8V0Z3L6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F5GYI3-1", "protein_name": "Ubiquitin-associated protein 1-like", "gene_name": "UBAP1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNALDGVPFKLPKGFVIGTEPLPGPELSVPACGEVLLGSMHDFSLERTALFWVEAAGQGPSPYQCGDPGTASAPPAWLLLVSPEHGLAPAPTTIRDPEAGHQERPEEEGEDEAEASSGSEEEPAPSSLQPGSPASPGPGRRLCSLDVLRGVRLELAGARRRLSEGKLVSRPRALLHGLRGHRALSLCPSPAQSPRSASPPGPAPQHPAAPASPPRPSTAGAIPPLRSHKPTVASLSPYTCLPPLGGAPQPLNPHKSHPDTAADLLSALSQEEQDLIGPVVALGYPLRRAIIALQKTGRQSLSQFLSYLSACDRLLRQGYEEGLVDEAMEMFQFSESQAGEFLRLWEQFSDMGFQQDRIKEVLLVHGNRREQALEELVACAQ", "length": 381 }, "evidence": [ { "id": "A0A8V0Z3L6", "url": "https://omabrowser.org/oma/group/A0A8V0Z3L6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "G3UW59-1", "protein_name": "Ubiquitin-associated protein 1-like", "gene_name": "Ubap1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNALDGVPFKVSKGFVMDTEPHPVPELSVPDCRELLLGTMYDFSLEKKALFWVEAAIRGSCSHQCNDLGIASAPPAWFLLASPKYSQVPAPAQIRDPEAGLQEPPEEEEEEEEEEEEETEEKGDEEDTSSACEEGMDSSSPQPGSPTSHRRCSLDVLRNMRSELADARRRLSESRLTACPRALLHRFRGHRTLSLSTSPAPAPGPAPQLPNVSELPPRPATAGAMPPLRNHKPTVASLSPYTCLPPLRETPQPLVSCRLHPDSAPDLLSALTEEEQDLIGPVVALGYPLGRAMEALQKTGRQSLSQFLGYLSACDRLLRQGYDEALVDEAMEMFQFSEHQAGEFLRLWKQFSDMGFQQDRIKEVLLVHASEGKTAASCTQPQNP", "length": 384 }, "evidence": [ { "id": "A0A8V0Z3L6", "url": "https://omabrowser.org/oma/group/A0A8V0Z3L6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R9J7-1", "protein_name": "Ubiquitin associated protein 1-like", "gene_name": "Ubap1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNALDGVPFKVPKGFVMNTEPHPVPELSVRDCRELLLGTMYDFSLEKKALFWVEAAVRGSCPHQCNDLGIASAPPAWFLLVNPNYSQVPAPAEIRDPETGQQEPPEEEDEEEEETEEKRDEEEASSTSEEGMDSSSPQPGSPTSHRRCSLDVLRNMRSELADARRRLSESRLATSPRALLHRFRAHRTLSLSASPAPTPGPALQPPNVSELPPRPSTAGAMPPLRSHKPTVASLSPYTCLPPLRETPQPLASCRLHPDSAPDLLSALTKEEQDLIRPVVALGYPLGRAIVALQKTGRQSLSQFLGYLSACERLLRQGYDEALVDEAMEMFQFSEHQAGEFLRLWQQFSDMGFQQDRIKEVLLVHGNQREQALEELVACAQ", "length": 380 }, "evidence": [ { "id": "A0A8V0Z3L6", "url": "https://omabrowser.org/oma/group/A0A8V0Z3L6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ESCRT I complex", "id": "GO:0000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway", "id": "GO:0043162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043162", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3L6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 379, "end_pos": 426, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z3L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3L6" }, { "id": "PS51497", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51497" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UMA", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 54, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 }, { "start_pos": 270, "end_pos": 272 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025005580", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025005580" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3P7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "F8A3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3P7", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z3P7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3P7", "database": "AlphaFoldDB", "categories": [] }, { "id": "776915", "url": "https://www.ncbi.nlm.nih.gov/gene/776915", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:776915", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776915", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELWQYAG", "url": "https://omabrowser.org/oma/group/ELWQYAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3P7", "url": "https://www.orthodb.org/?gene=A0A8V0Z3P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16797", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16797", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16797:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16797:SF4", "database": "PANTHER", 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CANONICAL=A0A8V0Z3P7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3P7/entry#A0A8V0Z3P7-1", "sequence": { "sequence": "MLAAAGGSGPGGAGGSGPGPGPGGGDGDFLSRYRLVSAKLRRRFLRKPNVAEAAEQFAALARELRAQESLPYAAWCQLAVARCAQSLFHGPAEAAALGEAARLFLRQERDLRQRLALRGGFGEHLAAAQSCGAFAARLHLERGQPALAAGLCLELAAALRDTGRPARAAAHFQRAAELLAAAKLPLEALRCLTERASCLLLGRDYAGALAALTRAQALAGAGAGIGGSGGAAPGGAFLDALVSCEVSRVLLLLLLQPPPGKLSPEHARTLEQYCWEAPEGGAAGGGLPAAASYLPAELFLLLQSAVLACQEKDAAALRALQAELWPLLSAEQNHLLHLVLQDMLSPAGHGL", "length": 351, "header": "tr|A0A8V0Z3P7-1|A0A8V0Z3P7_CHICK Isoform 1 of Coagulation factor VIII associated 3 OS=Gallus gallus OX=9031 GN=F8A3 PE=1 SV=1 CANONICAL=A0A8V0Z3P7-1" }, "locus": { "chromosome": "4", "start_pos": 2072647, "end_pos": 2071595, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046784.1", "url": "https://www.ensembl.org/id/ENSGALT00010046784.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027856.1", "url": "https://www.ensembl.org/id/ENSGALP00010027856.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:776915", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:776915", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2BIC9-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "f8a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAEGDFLMRYRAVSNKLKKRFLRKPNVAEASEQFGQLAKELKQQDCPQYAAFCNLAMARCEQTLFNAPGEALALTDAARLFLASEQETRALRAPGFDENMQAAMNCYSFAIKVYIEMNQPVMAASLSLELGNALKEMNRPGEAIIHFQRAAELQIQMPIEALLSLWEMASCKILTRDYDGALAVLSEMQHMCQERGLQLPGTNTPVGAFMDIIAKCEISRVLLLMLLEPPPQKLLPEHAQTLERYAWESFDSHSQVNFLPENVFLLLQSVVMACQEKDTESLKALQTELWPLLSAEQNHLLHLVVQERITPFGQGI", "length": 317 }, "evidence": [ { "id": "A0A8V0Z3P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z3P7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RZ35-1", "protein_name": "40-kDa huntingtin-associated protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAASAAGLGGGAGPGPESGDFLARYRQVSSKLKKRFLRKPNVAEAGEQFGQLGRELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLACPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRDLGQPAAAAGHFQRAAQLLLPQLPLAALQALGDAASCQLLARDYSGALAVFTRMQRLAWEHGSHPVQVPPPPPPPPPAALSQPQHQPRPPGLQPGSRAAAALPLALPPASAGSAAAPSPAALGAFSDVLVRCEVSRVLLLLLLQPPPAKLLPEHAHTLEKYSWEAFDSHGQESSGQLPEELFLLLQSLVMATHEKDTEAVKSLQVEMWPLLSAEQNHLLHLVLQETIWPSGQGI", "length": 386 }, "evidence": [ { "id": "A0A8V0Z3P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z3P7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0RDU0-1", "protein_name": "40-kDa huntingtin-associated protein", "gene_name": "F8a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGSASSLGGGSWPGSEAGDFLARYRQVSNKLKKRFLRKPNVAEAGEQFAQLARELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQECDARQRLGCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRAVGQPAAAAGHFQRAAQLHLPLMPLAALQALGDAASCQLLARDYTGALAVFTRMQRLAREHGGHPVQQPELPQQLPSVPQPSLPGPQPRPVLGSTLPLPLPPDHAPGSVAQSPGTLGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYSWEAFDGHGQDSSGQLPEELFLLLQSLVMAAHEKDTEGIKKLQVEMWPLLTAEQNHLLHLVLQETISPSGQGV", "length": 381 }, "evidence": [ { "id": "A0A8V0Z3P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z3P7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23610-1", "protein_name": "40-kDa huntingtin-associated protein", "gene_name": "F8A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAAGLGGGGAGPGPEAGDFLARYRLVSNKLKKRFLRKPNVAEAGEQFGQLGRELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLVCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRDLGQPAAAAGHFQRAAQLQLPQLPLAALQALGEAASCQLLARDYTGALAVFTRMQRLAREHGSHPVQSLPPPPPPAPQPGPGATPALPAALLPPNSGSAAPSPAALGAFSDVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYSWEAFDSHGQESSGQLPEELFLLLQSLVMATHEKDTEAIKSLQVEMWPLLTAEQNHLLHLVLQETISPSGQGV", "length": 371 }, "evidence": [ { "id": "A0A8V0Z3P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z3P7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q00558-1", "protein_name": "40-kDa huntingtin-associated protein", "gene_name": "F8a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGSASSLGGGAWPGSEAGDFLARYRQVSNKLKKRFLRKPNVAEAGEQFAQLARELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQECDARQRLGCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRAVGQPAAAAGHFQRAAQLHLPLMPLAALQALGDAASCQLLARDYTGALALFTRMQRLAREHGGHPVQQLELLPQPPSGPQPPLSGPQPRPVLGSTLPLPQPPDHAPGSVAPSPGTLGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYSWEAFDGHGQDTSGQLPEELFLLLQSLVMAAQEKDTEGIKKLQVEMWPLLTAEQNHLLHLVLQETISPSGQGV", "length": 381 }, "evidence": [ { "id": "A0A8V0Z3P7", "url": "https://omabrowser.org/oma/group/A0A8V0Z3P7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3P7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle cytoskeletal trafficking", "id": "GO:0099518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099518", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3P7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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16649.0, "monoisotopic_mass": 16649.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Bcl-2-like protein 11", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R2", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z3R2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3R2", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0Z3R2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKQPPEAKAPRDRRAGRLPPGEGPGPAVPLRPGAPAALPGAARPASPGSPGPFAIRSPLFFFVRRSPLLPRSSSGYFSFEAERSPAPMSCDKATQTPSPPCQAVSHYLSAMGECRAGRRGAGGGWQVALRGWRPAGRVWPRGAVCFGCCFFFFPSW", "length": 157, "header": "tr|A0A8V0Z3R2-1|A0A8V0Z3R2_CHICK Isoform 1 of Bcl-2-like protein 11 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z3R2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R2/entry#A0A8V0Z3R2-1", "sequence": { "sequence": "MAKQPPEAKAPRDRRAGRLPPGEGPGPAVPLRPGAPAALPGAARPASPGSPGPFAIRSPLFFFVRRSPLLPRSSSGYFSFEAERSPAPMSCDKATQTPSPPCQAVSHYLSAMGECRAGRRGAGGGWQVALRGWRPAGRVWPRGAVCFGCCFFFFPSW", "length": 157, "header": "tr|A0A8V0Z3R2-1|A0A8V0Z3R2_CHICK Isoform 1 of Bcl-2-like protein 11 OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z3R2-1" }, "locus": { "chromosome": "3", "start_pos": 3311905, "end_pos": 3311435, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046822.1", "url": "https://www.ensembl.org/id/ENSGALT00010046822.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027871.1", "url": "https://www.ensembl.org/id/ENSGALP00010027871.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "IQCK", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R8", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z3R8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3R8", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR043408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3R8", "url": "https://www.orthodb.org/?gene=A0A8V0Z3R8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34927", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34927", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34927:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34927:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3R8", "url": 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"start_pos": 14834221, "end_pos": 14810680, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042642.1", "url": "https://www.ensembl.org/id/ENSGALT00010042642.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025132.1", "url": "https://www.ensembl.org/id/ENSGALP00010025132.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z498-1", "uniprot_ac": "A0A8V0Z498", "uniprot_id": "A0A8V0Z498_CHICK", "mass": { "chemical_mass": 56300.0, "monoisotopic_mass": 56300.0 }, "refseq": { "ac": "NP_001316426", "name": "cytochrome P450 2AB5 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316426" }, "gene_names": [ { "name": "CYP2AB5", "type": "recommended", "evidence": [ { "id": "A0A8V0Z498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z498" } ] }, { "name": "CYP2AB5", "type": "synonym", "evidence": [ { "id": "NP_001316426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316426" } ] }, { "name": "CYP2J6L3", "type": "synonym", "evidence": [ { "id": "NP_001316426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316426" } ] } ], "protein_names": [ { "name": "Cytochrome P450, family 2, subfamily AB, polypeptide 5", "type": "synonym", "evidence": [ { "id": "A0A8V0Z498", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z498/entry#names_and_taxonomy" } ] }, { "name": "cytochrome P450 2AB5 precursor", "type": "synonym", "evidence": [ { "id": "NP_001316426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316426" } ] }, { "name": "cytochrome P450 2AB5", "type": "synonym", "evidence": [ { "id": "NP_001316426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316426" } ] }, { "name": "cytochrome P450 2J6-like 3", "type": "synonym", "evidence": [ { "id": "NP_001316426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316426" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02738217 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. On Oct 4, 2021 this sequence version replaced NP_001316426.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001316426", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316426" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z498", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z498" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYP2AB5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z498", "locus": { "chromosome": "9", "start_pos": 15338295, "end_pos": 15348991, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017917", "url": "https://www.ensembl.org/id/ENSGALG00010017917" } ] } } ], "crossref": [ { "id": "A0A8V0Z498", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z498", "database": "AlphaFoldDB", "categories": [] }, { "id": "429152", "url": "https://www.ncbi.nlm.nih.gov/gene/429152", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:429152", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429152", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WFGWTPV", "url": "https://omabrowser.org/oma/group/WFGWTPV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3R9", "url": "https://www.orthodb.org/?gene=A0A8V0Z3R9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z498", "url": "https://www.orthodb.org/?gene=A0A8V0Z498", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300:SF411", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300:SF411", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001316426", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316426", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3R9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3R9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z498", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z498", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z498-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z498-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTISQALVILVIFLLSVQFLKLQKARQQFPPGPTPLPLLGNLLHLKFQFHRDLLMELAKTYGNIYTLWFGWTPVIILNGFQAVKDGMTTHPEDVAGRMVSPFIREMAKGKGILLASGRSWKQQRRFGIMTLRNLGMGKKGLEYRVQEEAAHLVEIFRNLKGRPMDPSFHLFHSISNVICAVVFGYHFSDEDKTFRELISATEEIFSFAGSFVYQLYEILPWLMCRLPGPHKKVLSCYDVLSSFSRMEVRRHVERGTPDEPQDFIDFYLAEIEKSKDEDKPKYDEDNLVHVINDLFLGGSETSSTTLYWGLLYMVVYPDIQEKVQKELDTVLDPSQTICYEHRKKLPYTNAVIHEIQRFSNIVFVGLPRVCVRNTTLLGYPVKKGTIVVPNIASVLYDPEQWETPRQFNPDHFLDKEGSFVNREAFLPFSAGHRVCLGEHLARTELFIFFANLLRAFTFRLPEGVTTINTEPIFGGTLQPHPYKVCAIPR", "length": 490, "header": "tr|A0A8V0Z498-1|A0A8V0Z498_CHICK Isoform 1 of Cytochrome P450, family 2, subfamily AB, polypeptide 5 OS=Gallus gallus OX=9031 GN=CYP2AB5 PE=3 SV=1 CANONICAL=A0A8V0Z498-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3R9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z498/entry#A0A8V0Z3R9-1", "sequence": { "sequence": "MELAKTYGNIYTLWFGWTPVIILNGFQAVKDGMTTHPEDVAGRMVSPFIREMAKGKGILLASGRSWKQQRRFGIMTLRNLGMGKKGLEYRVQEEAAHLVEIFRNLKGRPMDPSFHLFHSISNVICAVVFGYHFSDEDKTFRELISATEEIFSFAGSFVYQLYEILPWLMCRLPGPHKKVLSCYDVLSSFSRMEVRRHVERGTPDEPQDFIDFYLAEIEKSKDEDKPKYDEDNLVHVINDLFLGGSETSSTTLYWGLLYMVVYPDIQEKVQKELDTVLDPSQTICYEHRKKLPYTNAVIHEIQRFSNIVFVGLPRVCVRNTTLLGYPVKKGTIVVPNIASVLYDPEQWETPRQFNPDHFLDKEGSFVNREAFLPFSAGHRVCLGEHLARTELFIFFANLLRAFTFRLPEGVTTINTEPIFGGTLQPHPYKVCAIPR", "length": 435, "header": "tr|A0A8V0Z3R9-1|A0A8V0Z498_CHICK Computationally mapped isoform of Cytochrome P450, family 2, subfamily AB, polypeptide 5 OS=Gallus gallus OX=9031 GN=CYP2AB5 PE=3 SV=1 CANONICAL=A0A8V0Z498-1" }, "locus": { "chromosome": "9", "start_pos": 15348684, "end_pos": 15340683, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043316.1", "url": "https://www.ensembl.org/id/ENSGALT00010043316.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025746.1", "url": "https://www.ensembl.org/id/ENSGALP00010025746.1" } ] } }, { "isoform_ac": "A0A8V0Z498-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z498/entry#A0A8V0Z498-1", "sequence": { "sequence": "MLTISQALVILVIFLLSVQFLKLQKARQQFPPGPTPLPLLGNLLHLKFQFHRDLLMELAKTYGNIYTLWFGWTPVIILNGFQAVKDGMTTHPEDVAGRMVSPFIREMAKGKGILLASGRSWKQQRRFGIMTLRNLGMGKKGLEYRVQEEAAHLVEIFRNLKGRPMDPSFHLFHSISNVICAVVFGYHFSDEDKTFRELISATEEIFSFAGSFVYQLYEILPWLMCRLPGPHKKVLSCYDVLSSFSRMEVRRHVERGTPDEPQDFIDFYLAEIEKSKDEDKPKYDEDNLVHVINDLFLGGSETSSTTLYWGLLYMVVYPDIQEKVQKELDTVLDPSQTICYEHRKKLPYTNAVIHEIQRFSNIVFVGLPRVCVRNTTLLGYPVKKGTIVVPNIASVLYDPEQWETPRQFNPDHFLDKEGSFVNREAFLPFSAGHRVCLGEHLARTELFIFFANLLRAFTFRLPEGVTTINTEPIFGGTLQPHPYKVCAIPR", "length": 490, "header": "tr|A0A8V0Z498-1|A0A8V0Z498_CHICK Isoform 1 of Cytochrome P450, family 2, subfamily AB, polypeptide 5 OS=Gallus gallus OX=9031 GN=CYP2AB5 PE=3 SV=1 CANONICAL=A0A8V0Z498-1" }, "locus": { "chromosome": "9", "start_pos": 15348849, "end_pos": 15340683, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043320.1", "url": "https://www.ensembl.org/id/ENSGALT00010043320.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025748.1", "url": "https://www.ensembl.org/id/ENSGALP00010025748.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 35, "start_aa": "Thr", "end_pos": 35, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr35", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:429152", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:429152", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z498", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z498" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z498", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z498" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z498", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z498" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation 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"RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPAPPHPSPLCVPPPRGRAVQPRPAPPLYPHRSAPSSRPLPMATADAAAPTPAGEQRPERSDSSSGTAAGGGAAAASAAGRAAASGGGGGGGGSSLELAAARRRLVAAECRRRAAAELEGRVVQVHCALRHAELRLAARAEALSRLGSGVAQAQLALAAQGQRLQKGLRRRPRPRPGALLAAARALRSCVPWAAGRARRSSVHTPSRRLPAAPRSPA", "length": 217, "header": "tr|A0A8V0Z3U4-1|A0A8V0Z3U4_CHICK Isoform 1 of TMF1 regulated nuclear protein 1 OS=Gallus gallus OX=9031 GN=TRNP1 PE=4 SV=1 CANONICAL=A0A8V0Z3U4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U4/entry#A0A8V0Z3U4-1", "sequence": { "sequence": "MPAPPHPSPLCVPPPRGRAVQPRPAPPLYPHRSAPSSRPLPMATADAAAPTPAGEQRPERSDSSSGTAAGGGAAAASAAGRAAASGGGGGGGGSSLELAAARRRLVAAECRRRAAAELEGRVVQVHCALRHAELRLAARAEALSRLGSGVAQAQLALAAQGQRLQKGLRRRPRPRPGALLAAARALRSCVPWAAGRARRSSVHTPSRRLPAAPRSPA", "length": 217, "header": "tr|A0A8V0Z3U4-1|A0A8V0Z3U4_CHICK Isoform 1 of TMF1 regulated nuclear protein 1 OS=Gallus gallus OX=9031 GN=TRNP1 PE=4 SV=1 CANONICAL=A0A8V0Z3U4-1" }, "locus": { "chromosome": "23", "start_pos": 2210306, "end_pos": 2209656, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043097.1", "url": "https://www.ensembl.org/id/ENSGALT00010043097.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025587.1", "url": "https://www.ensembl.org/id/ENSGALP00010025587.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 51, "start_aa": "Thr", "end_pos": 51, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr51", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:107054997", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107054997", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K0Y1-1", "protein_name": "TMF1-regulated nuclear protein 1", "gene_name": "Trnp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGCRISACGPGAQEGTAEPGSPPPPPREPLPSLQPPSSSPTSTPTSTQSPQLPEAAETPVEGQELQRWRQGASGGSGGASPAGIGGAGAAAGAGGRALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLSRLSGGVAQAELYLAAHGSRLKKGARRGRRGRPPALLASALGLGSCVPWGAGRLRRGQGPEPDSPFRRSPPRGPASPQR", "length": 225 }, "evidence": [ { "id": "A0A8V0Z3U4", "url": "https://omabrowser.org/oma/group/A0A8V0Z3U4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1LW65-1", "protein_name": "TMF1 regulated nuclear protein 1", "gene_name": "TRNP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPGCRISACGPGAQEGSAEPGSPPPPPPREPLSCPQPPSPSPTLTPTRAQASSQPGAAQESAGSAEGLELQRWRQGASGGAGGPGPAGGAGGGSGAAAAAAGVRALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLGRLGGGVAQAELYLAAHGPRLKKGSRRVRRARPPALLASALGLGGCVPWGAGRLRRGHGPEPESPFRRSPPRGPASPQR", "length": 232 }, "evidence": [ { "id": "A0A8V0Z3U4", "url": "https://omabrowser.org/oma/group/A0A8V0Z3U4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LDS2-1", "protein_name": "TMF1 regulated nuclear protein 1", "gene_name": "TRNP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGCRISACGPGAQEGTAEPGSPPPPPREPLSSPEPPPSTPTLTPTPAQASPLPEVVPESAGSAEGQELQRWRQGASGGAGGTGPAGGAGGGPSKVAAAAAGSGGRALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLGRLSGGVAQAELYLAAHGSRLKKGSRRGRRARPPALLASALGLGGCVPWGAGRLRRGHGPEPDSPFRRSPPRGPASPQR", "length": 234 }, "evidence": [ { "id": "A0A8V0Z3U4", "url": "https://omabrowser.org/oma/group/A0A8V0Z3U4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6NT89-1", "protein_name": "TMF-regulated nuclear protein 1", "gene_name": "TRNP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGCRISACGPGAQEGTAEQRSPPPPWDPMPSSQPPPPTPTLTPTPTPGQSPPLPDAAGASAGAAEDQELQRWRQGASGIAGLAGPGGGSGAAAGAGGRALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLSRLSGGVAQAELYLAAHGSRLKKGPRRGRRGRPPALLASALGLGGCVPWGAGRLRRGHGPEPDSPFRRSPPRGPASPQR", "length": 227 }, "evidence": [ { "id": "A0A8V0Z3U4", "url": "https://omabrowser.org/oma/group/A0A8V0Z3U4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80ZI1-1", "protein_name": "TMF-regulated nuclear protein 1", "gene_name": "Trnp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGCRISACGPGAQEGTAEPGSPPPPPREPLPSLQPPSPSPTSTPTPTKSPPLPEAAETPVEGQELQRWRQGASGGSGGAGPAGIAGAAAGAGGRALELAEARRRLLEVEGRRRLVSELESRVLQLHRVFLAAELRLAHRAESLSRLSGGVAQAELYLAAHGSRLKKGARRGRRGRPPALLASALGLGSCVPWGAGRLRRGQGPEPDSPFRRSPPRGPASPQR", "length": 223 }, "evidence": [ { "id": "A0A8V0Z3U4", "url": "https://omabrowser.org/oma/group/A0A8V0Z3U4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cerebellar cortex morphogenesis", "id": "GO:0021696", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021696", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U4" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U4" } ], "pmid": "" }, { "name": "neural precursor cell proliferation", "id": "GO:0061351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U4" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U4" } ], "pmid": "" }, { "name": "euchromatin", "id": "GO:0000791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000791", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 51 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3U9-1", "uniprot_ac": "A0A8V0Z3U9", "uniprot_id": "A0A8V0Z3U9_CHICK", "mass": { "chemical_mass": 210778.0, "monoisotopic_mass": 210778.0 }, "refseq": { "ac": "XP_015147730", "name": "C-myc promoter-binding protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147730" }, "gene_names": [ { "name": "DENND4A", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9" } ] }, { "name": "DENND4A", "type": "synonym", "evidence": [ { "id": "XP_015147730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147730" } ] } ], "protein_names": [ { "name": "C-myc promoter-binding protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015147730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147730" } ] }, { "name": "DENN domain containing 4A", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052541.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015147730.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015147730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147730" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "DENND4A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9", "locus": { "chromosome": "10", "start_pos": 18115247, "end_pos": 18159768, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017830", "url": "https://www.ensembl.org/id/ENSGALG00010017830" } ] } } ], "crossref": [ { "id": "415541", "url": "https://www.ncbi.nlm.nih.gov/gene/415541", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415541", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415541", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LMTIAME", "url": "https://omabrowser.org/oma/group/LMTIAME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3U9", "url": "https://www.orthodb.org/?gene=A0A8V0Z3U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4Z1", "url": "https://www.orthodb.org/?gene=A0A8V0Z4Z1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12296", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12296", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12296:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12296:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8876198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015147730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015147730", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Z1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDKGARVADYFVVAGLTDISKPLEEEIHFNDACHKIAKPKEPITDVTVIIKSLGEEVPQGYKCIDVTPSGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDGKERVKQGCEIIQATPYGRPANISGNASSQRVFITYRRASENMTQNTLAVTDICIIIPSKGETPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTISYKAGLICRYPEEDYESFPLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYPEENLTEKQKSQLGLAAVEGKSDSCRTVQTNKCICLLSHWPFFDAFKKFLTFLYRYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPYDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQTGDKKAIAWKILPKKPCKNLMNTLNNLYQQLAVQQRPREDALMELAMNDYDFNSGKKLHLLDLEIQEAFLCFMASILKGYRSYLRPITEAPSETATDASSLFELQGFLKSRDRSHQKFYTLMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDTDKTGETRLIELDESYKSEHTVFITPPEIPHLPNGEEHPLQYSYNGFPVLKLELFERPEGLLTIPNNKLSSKASSPNSPSPMFRRTKQEIKSAHKIAKKYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRALRTAYDVLQKMHTKKIDPPDEVCYRVLMQLCGQYGQPVLAVRVLFEMQKAGVDPNAITYGYYNKAVLESTWPSSNRGGYFLWMKIRNVVLGIAQFKRALKKLPTSSSHTALPGGLSDLGSNTSFKDETRQGKTCLQDIQEQKEDKRESDSSSLSEVESAKGSGDCLPKLNYHNSNNDKGTSSIVRLNGTIDNTVAEASTESSVGLLFTSSFDDANEAEVIKSKSLRRRHKSAAEPDVREIPWESRNRNLSGDGLVGLMINRINQEANPGEMVEKLGADAKILSSALQKSIRPKTLNIRSSSLGSKRESLEKESSDEDAAFDCSFTDKTESPVIFDLEDLDAEPETSTTVKTSSEKSRRLQRKSSFPVKPVEKTDVETGFDPLSLLVAETEQQKEDEEEDDDRSASTPSARRDLAEEIVMYMNNMSSPLSSRAPSIELQKPFDDRNVNKKSPTVIQACRRSSLPPNSPRPSSLIKSKSYHSKAEERSRDRLWSSPAYSPHSPAKEQEGTGALPLVSSPSFNLDTLLTPKFDVLKSSMFSAGKGVAEKASKWYSKFAMYAASSKDQNSDRASVSSLGALDSESTSLTDEDVCNDFESTSPQENATSEIKGIGLSRTSLESSASHDGSSKQFDQCGSLSKFPLPDKSELISSCSTSSTSVFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNLFLPFLSIEIRDLRRPGRYFLKSSPSTENMQFPSLYSNPNGKSCNTAATAGLTTSLMSVQEDIHSDSNSKQSDNTCARSIQIPSGRRQNTSGSECTSHPVARSISTFGPLEEDEKESQKINHIIPTGSLPATLQGPTDPLGLDWRLPSPDPITVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKNSKIPRNCMSEDSKYVLIQMLWDNMKLHQDPRQPLYILWNAQSQNRTLLFETQKYPMVHLLQKDDDSFNQELLRSMVKSIKMNDVYGPMSQILERLNKWPHIKRQRSLYREILFLSLVALGRDNIDIDAFDREYKMAYDRLTANQVKNTHNCDRPPSTGVMECRKIFGEPYL", "length": 1883, "header": "tr|A0A8V0Z3U9-1|A0A8V0Z3U9_CHICK Isoform 1 of DENN domain containing 4A OS=Gallus gallus OX=9031 GN=DENND4A PE=4 SV=1 CANONICAL=A0A8V0Z3U9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9/entry#A0A8V0Z3U9-1", "sequence": { "sequence": "MEDKGARVADYFVVAGLTDISKPLEEEIHFNDACHKIAKPKEPITDVTVIIKSLGEEVPQGYKCIDVTPSGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDGKERVKQGCEIIQATPYGRPANISGNASSQRVFITYRRASENMTQNTLAVTDICIIIPSKGETPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTISYKAGLICRYPEEDYESFPLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYPEENLTEKQKSQLGLAAVEGKSDSCRTVQTNKCICLLSHWPFFDAFKKFLTFLYRYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPYDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQTGDKKAIAWKILPKKPCKNLMNTLNNLYQQLAVQQRPREDALMELAMNDYDFNSGKKLHLLDLEIQEAFLCFMASILKGYRSYLRPITEAPSETATDASSLFELQGFLKSRDRSHQKFYTLMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDTDKTGETRLIELDESYKSEHTVFITPPEIPHLPNGEEHPLQYSYNGFPVLKLELFERPEGLLTIPNNKLSSKASSPNSPSPMFRRTKQEIKSAHKIAKKYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRALRTAYDVLQKMHTKKIDPPDEVCYRVLMQLCGQYGQPVLAVRVLFEMQKAGVDPNAITYGYYNKAVLESTWPSSNRGGYFLWMKIRNVVLGIAQFKRALKKLPTSSSHTALPGGLSDLGSNTSFKDETRQGKTCLQDIQEQKEDKRESDSSSLSEVESAKGSGDCLPKLNYHNSNNDKGTSSIVRLNGTIDNTVAEASTESSVGLLFTSSFDDANEAEVIKSKSLRRRHKSAAEPDVREIPWESRNRNLSGDGLVGLMINRINQEANPGEMVEKLGADAKILSSALQKSIRPKTLNIRSSSLGSKRESLEKESSDEDAAFDCSFTDKTESPVIFDLEDLDAEPETSTTVKTSSEKSRRLQRKSSFPVKPVEKTDVETGFDPLSLLVAETEQQKEDEEEDDDRSASTPSARRDLAEEIVMYMNNMSSPLSSRAPSIELQKPFDDRNVNKKSPTVIQACRRSSLPPNSPRPSSLIKSKSYHSKAEERSRDRLWSSPAYSPHSPAKEQEGTGALPLVSSPSFNLDTLLTPKFDVLKSSMFSAGKGVAEKASKWYSKFAMYAASSKDQNSDRASVSSLGALDSESTSLTDEDVCNDFESTSPQENATSEIKGIGLSRTSLESSASHDGSSKQFDQCGSLSKFPLPDKSELISSCSTSSTSVFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNLFLPFLSIEIRDLRRPGRYFLKSSPSTENMQFPSLYSNPNGKSCNTAATAGLTTSLMSVQEDIHSDSNSKQSDNTCARSIQIPSGRRQNTSGSECTSHPVARSISTFGPLEEDEKESQKINHIIPTGSLPATLQGPTDPLGLDWRLPSPDPITVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKNSKIPRNCMSEDSKYVLIQMLWDNMKLHQDPRQPLYILWNAQSQNRTLLFETQKYPMVHLLQKDDDSFNQELLRSMVKSIKMNDVYGPMSQILERLNKWPHIKRQRSLYREILFLSLVALGRDNIDIDAFDREYKMAYDRLTANQVKNTHNCDRPPSTGVMECRKIFGEPYL", "length": 1883, "header": "tr|A0A8V0Z3U9-1|A0A8V0Z3U9_CHICK Isoform 1 of DENN domain containing 4A OS=Gallus gallus OX=9031 GN=DENND4A PE=4 SV=1 CANONICAL=A0A8V0Z3U9-1" }, "locus": { "chromosome": "10", "start_pos": 18147690, "end_pos": 18116251, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043102.1", "url": "https://www.ensembl.org/id/ENSGALT00010043102.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025592.1", "url": "https://www.ensembl.org/id/ENSGALP00010025592.1" } ] } }, { "isoform_ac": "A0A8V0Z4Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9/entry#A0A8V0Z4Z1-1", "sequence": { "sequence": "MEDKGARVADYFVVAGLTDISKPLEEEIHFNDACHKIAKPKEPITDVTVIIKSLGEEVPQGYKCIDVTPSGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDGKERVKQGCEIIQATPYGRPANISGNASSQRVFITYRRASENMTQNTLAVTDICIIIPSKGETPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTISYKAGLICRYPEEDYESFPLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYPEENLTEKQKSQLGLAAVEGKSDSCRTVQTNKCICLLSHWPFFDAFKKFLTFLYRYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPYDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQTGDKKAIAWKILPKKPCKNLMNTLNNLYQQLAVQQRPREDALMELAMNDYDFNSGKKLHLLDLEIQEAFLCFMASILKGYRSYLRPITEAPSETATDASSLFELQGFLKSRDRSHQKFYTLMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDTDKTGETRLIELDESYKSEHTVFITPPEIPHLPNGEEHPLQYSYNGFPVLKLELFERPEGLLTIPNNKLSSKASSPNSPSPMFRRTKQEIKSAHKIAKKYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRALRTAYDVLQKMHTKKIDPPDEVCYRVLMQLCGQYGQPVLAVRVLFEMQKAGVDPNAITYGYYNKAVLESTWPSSNRGGYFLWMKIRNVVLGIAQFKRALKKLPTSSSHTALPGGLSDLGSNTSFKDETRQGKTCLQDIQEQKEDKRESDSSSLSEVESAKGSGDCLPKLNYHNSNNDKGTSSIVRLNGTIDNTVAEASTESSVGLLFTSSFDDANEAEVIKSKSLRRRHKSAAEPDVREIPWESRNRNLSGDGLVGLMINRINQEANPGEMVEKLGADAKILSSALQKSIRPKTLNIRSSSLGSKRESLEKESSDEDAAFDCSFTDKTESPVIFDLEDLDAEPETSTTVKTSSEKSRRLQRKSSFPVKPVEKTDVETGFDPLSLLVAETEQQKEDEEEDDDRSASTPSARRDLAEEIVMYMNNMSSPLSSRAPSIELQKPFDDRNVNKKSPTVIQACRRSSLPPNSPRPSSLIKSKSYHSKAEERSRDRLWSSPAYSPHSPAKEQEGTGALPLVSSPSFNLDTLLTPKFDVLKSSMFSAGKGVAEKASKWYSKFAMYAASSKDQNSDRASVSSLGALDSESTSLTDEDVCNDFESTSPQENATSEIKGIGLSRTSLESSASHDGSSKQFDQCGSLSKFPLPDKSELISSCSTSSTSVFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNLFLPFLSIEIRDLRRPGRYFLKSSPSTENMQFPSLYSNPNGKSCNTAATAGLTTSLMSVQEDIHSDSNSKQSDNTCARSIQIPSGRRQNTSGSECTSHPVARSISTFGPLEEDEKESQKINHIIPTGSLPATLQGPTDPLGLDWRLPSPDPITVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKNSKIPRNCMSEDSKYVLIQMLWDNMKLHQDPRQPLYILWNAQTQKYPMVHLLQKDDDSFNQELLRSMVKSIKMNDVYGPMSQILERLNKWPHIKRQRSLYREILFLSLVALGRDNIDIDAFDREYKMAYDRLTANQVKNTHNCDRPPSTGVMECRKIFGEPYL", "length": 1874, "header": "tr|A0A8V0Z4Z1-1|A0A8V0Z4Z1_CHICK Computationally mapped isoform of DENN domain containing 4A OS=Gallus gallus OX=9031 GN=DENND4A PE=4 SV=1 CANONICAL=A0A8V0Z3U9-1" }, "locus": { "chromosome": "10", "start_pos": 18147690, "end_pos": 18116251, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043106.1", "url": "https://www.ensembl.org/id/ENSGALT00010043106.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025596.1", "url": "https://www.ensembl.org/id/ENSGALP00010025596.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1193, "start_aa": "Thr", "end_pos": 1193, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1193", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1645, "start_aa": "Thr", "end_pos": 1645, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1645", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415541", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415541", "resource": "KEGG Pathway" }, { "id": "R-GGA-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9ST20-1", "protein_name": "DENN domain containing 4A", "gene_name": "DENND4A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIEDKGPRVADYFVVAGLTDVSKPLEEEIHFNDACHKVARPKEPITDVSVIIKSLGEEVPRDYTCIDITPTGLSADLNNGSLVGPQIFLCYRRGRDKPPLTDLGVLYDWKERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTISYKAGLICRYPQEDYESFSLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYSEENLTEKQRFLLGLASSANEKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLYRYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQTGDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKLQQRPRDDGLMDLAMNDYDFNSGKRLHMIDLEIQEAFLCFMASILKGYRSYLRPITQAPSETATDATSLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNNLFERPEGFLQTRKSKLPSKSSSPSSPSPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRALKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLGVAQFKRALKKHANLSQTALSDGSDLDAVSHGSMDSGHGTHAVEQAPCSTGSIKAYASDDRSSTGGQSDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDSSSLSECESAKGSADCLPKLGYQSSSSIVRLNGTSNSADKISGESTESTSEPLLISSFEDANETGNIQSRCFRKRHKSDNEPDLQQQMSWVNRSRNLSGGVLMGLMLSRINQEANPGNMVEKLGADAKILSNVISKSTRPNSLNIGKPSLRSKRDSVEKESSDDDTPFDGSNCLTDKVDSPVIFDLEDLDNETDISKARYIVPQNPKRSQRLNSSFSIKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEEEDDSKSVSTPSARRDLAEEIEMYMNNMSSPLTSRTPSIDLQRACDDKVTTKKSPTLVKACRRSSLPPNSPRPVRLTKSKSYSKNEDRPRDRLWSSPAFSPTCPFREESQDALTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGATSQESSATSGTKGVDFSRTSLEGSASLEGSLSKFALPGKSEVASSCNTSNTNIFQNYAMEVLISSCSRCKTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNLFLPFLNIEIRDLRRPGRYFLKSSPSTENIHFPSSFSSQTRQSCISTSTSGLDTSLLSVHGSFDLNSKSKPLENTCARSIQIPADRSKAAMSKCPLFPMARSVSTYGTLDQEDIGGQKLVPTGSLPTTLQGAADSLGLEWHLPSPDPITVPYLSPLVVWKELESLLENEGDRAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHSQNRTLLFETQKYPMVHLLQKGDNSFNQELLKNMVKSIKMNDVYGPMSQILDTLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVMECRKTFGEPYL", "length": 1915 }, "evidence": [ { "id": "A0A8V0Z3U9", "url": "https://omabrowser.org/oma/group/A0A8V0Z3U9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A518-1", "protein_name": "DENN domain containing 4A", "gene_name": "Dennd4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIEDKGPRVADYFVVAGLTDISKPLEEEIHFNDACHKVARPKEPITDVSVIIKSLGEEVPQDYVCIDVTPTGLSADLNNGSLVGPQIYLCYKRGRDKPPLTDLGVLYDWKERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENTTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTISYKAGLICRYPQEDYESFSLPESVPLFCLPMGATIECWPPDSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYSEENLTEKQRLLLGLTSLVDGKSDGSRTIHTNKCICLLSHWPFFDAFRKFLTFLYRYSISGPHALPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQTGDKKNVAWKILPKKPCKNLMNTLHNLHQQLAKLQQRPRDDGLMDLAMNDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITEAPSETATDATSLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDTDKSGEVRLIELDASFKSEHTVFVTPPEIPQLPNGEEPPLQYSYNGFPVLRNNLFERPEGFLQARKNKLPSKPSSPGSPSPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRALKTAYDVLKKMQLKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKIRNVVLGVAQFKRALKKHPHLPQTALSGGRSDLGYSSLCKDDVRREATSTEDIQGEKDKKGSDSSSLSENESAKGSADCLPSLSYQSSSTIVRLSGTNQDGADKMSGECEESTPELLLVPSCNDTNEAQTMPSRCFRKRHKSDDESHLQQQMPWGNRNRNLSGGVLMRFMLNRINQETNPGDMVEKLGADAKILSNVISKSTRPNSLDIGKPPVRSKRDSLEKESSDDDTPFDASNCLDKVESPVIFDLEDLDTETDGSKVGCVAAQNPKRLQRMNSSFSVKPSEKTDVVTGFDPLSLLVAETEQQQKVEEEDDEDDNKSISTPSARRNLAEEIEMYMNNMSSPLTSRTPSIDLQRASDEKLTNKKSPTLVKACRRSSLPPNSPRPVRLTKSKSYTKSEERPRDRLWSSPAFSPTCPFREGSQETLAHSSPSFNLDTLLVPKLDVLRHSVFTAGKGVAEKASKWYSRFAMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGATSSQESSAASGTKGIDASRASLGSSASLEGSLSKFALPGKTETASSLNTSNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNLFLPFLNVEIRDLRRPGRYFLKSSSSTETMHFASSFSSRTRQSCISASASGLDTSSLSVQGNLDLNNKSKLQENPCARSIQIPAHRSKTVVSKCPLFPMARSISTCGPLDKDEPGGQKLIPTGSLPATLQGPTDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHSQNRTLLFETQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLSKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVMECRKTFGEPYL", "length": 1873 }, "evidence": [ { "id": "A0A8V0Z3U9", "url": "https://omabrowser.org/oma/group/A0A8V0Z3U9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q8V6-1", "protein_name": "DENN domain containing 4A", "gene_name": "Dennd4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIEDKGPRVADYFVVAGLTDISKPLEEEIHFNDACHKVAKPKEPITDVSVIIKSLGEEVPRDYVCIDVTPTGLSADLNNGSLVGPQIYLCYKRGRDKPPLTDLGVLYDWKERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENTTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLSNSMWGSAVYLCYKKSVAKTNTISYKAGLICRYPQEDYESFSLPESVPLFCLPMGATIECWPPDSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYPEENLTEKQRLLLGLTSLVDGKSDSTRTIHTNKCICLLSHWPFFDAFRKFLTFLYRYSISGPHALPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDLDTNTISQTGDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKLQQRPRDDGLMDLAMNDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDATSLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDTDKSGEVRLIELDASFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNNLFERPEGFLQARKNKLPSKPSSPGSPSPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRALKTAYDVLKKMQLKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLGVAQFKRALKKHPHLPQTALSGGRSDLGYNSLSKDNVRREGPSTEDIQGEKEKRGSDSSSLSENESTKGSAECLPTLSYQRASTIVRLNGAHNDSAGKTSGECEESTPELLLMPSLEDTNEAQTTPSRCFRKRHKSDDGSHLQQQMPWGSRNRNLSGGVLMGFMLNRTNQETSPGEMVEKLGADAKILSNVISKSTRPNSLDIGKPPARSKRDSLEKESSDDDTPFHGSNCLDKVESPVIFDLEDLDTETDGSKVGGVAAQNPKRLQRRNSSFSVKPSEKTDVVTGFDPLSLLVAETEQQQKVEEEEDEDDNKSVSTPSARRNLAEEIEMYMNNMSSPLTSRTPSIDLQRACDDKLTNKKSPTLVKACRRSSLPPNSPRPVRLTKSKSYTKSEERPRDRLWSSPAFSPTCPFREGSQETLAHSSPSFNLDTLLVPKLDVLRHSVFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGATSSQESSAASGTKGIDVSRASLGSSASLEGSLSKFALPGKSETASSLNTSNANIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNLFLPFLNVEIRDLRRPGRYFLKSSSSTETMHFASRTRQSCISASASGLDTSSLSVQGNFDLNNKSKLQENPCARSIQIPAHRSKTVVSKCPLFPMARSISTCGPLDKDDPGGQKLIPTGSLPATLQGHTDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHSQNRTLLFETQKYPMVHLLQKGDDSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVMECRKTFGEPYL", "length": 1869 }, "evidence": [ { "id": "A0A8V0Z3U9", "url": "https://omabrowser.org/oma/group/A0A8V0Z3U9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z401-1", "protein_name": "C-myc promoter-binding protein", "gene_name": "DENND4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIEDKGPRVADYFVVAGLTDVSKPLEEEIHFNDACHKVAKPKEPITDVSVIIKSLGEEVPQDYICIDVTPTGLSADLNNGSLVGPQIYLCYRRGRDKPPLTDLGVLYDWKERLKQGCEIIQSTPYGRPANISGSTSSQRIYITYRRASENMTQNTLAVTDICIIIPSKGESPPHTFCKVDKNLNNSMWGSAVYLCYKKSVAKTNTVSYKAGLICRYPQEDYESFSLPESVPLFCLPMGATIECWPSNSKYPLPVFSTFVLTGASAEKVYGAAIQFYEPYSEENLTEKQRLLLGLTSADGKSDSSKTIHTNKCICLLSHWPFFDAFRKFLTFLYRYSISGPHVLPIEKHISHFMHKVPFPSPQRPRILVQLSPHDNLILSQPVSSPLPLSGGKFSTLLQNLGPENAVTLLVFAVTEHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRYFDLYDPPPDVSCVDVDTNTISQIGDKKNVAWKILPKKPCKNLMNTLNNLHQQLAKLQQRPRDDGLMDLAINDYDFNSGKRLHMIDLEIQEAFLFFMASILKGYRSYLRPITQAPSETATDAASLFALQAFLRSRDRSHQKFYNMMTKTQMFIRFIEECSFVSDKDASLAFFDDCVDKVDMDKSGEVRLIELDESFKSEHTVFVTPPEIPHLPNGEEPPLQYSYNGFPVLRNNLFERPEGFLQAKKNKLPSKSSSPNSPLPMFRRTKQEIKSAHKIAKRYSSIPQMWSRCLLRHCYGLWFICLPAYVKVCHSKVRALKTAYDVLKKMQSKKMDPPDEVCYRILMQLCGQYDQPVLAVRVLFEMQKAGIDPNAITYGYYNKAVLESTWPSRSRSGYFLWTKVRNVVLGVTQFKRALKKHAHLSQTTLSGGQSDLGYNSLSKDEVRRGDTSTEDIQEEKDKKGSDCSSLSESESTKGSADCLPKLSYQNSSSIVRLTGTSNNSAGKISGESMESTPELLLISSLEDTNETRNIQSRCFRKRHKSDNETNLQQQVVWGNRNRNLSGGVLMGFMLNRINQEATPGDIVEKLGADAKILSNVISKSTRPNTLDIGKPPLRSKRDSLEKESSDDDTPFDGSNYLADKVDSPVIFDLEDLDSETDVSKAGCVATQNPKRIQRMNSSFSVKPFEKTDVATGFDPLSLLVAETEQQQKEEEEEDEDDSKSISTPSARRDLAEEIVMYMNNMSSPLTSRTPSIDLQRACDDKLNKKSPPLVKACRRSSLPPNSPKPVRLTKSKSYTKSEEKPRDRLWSSPAFSPTCPFREESQDTLTHSSPSFNLDTLLVPKLDVLRNSMFTAGKGVAEKASKWYSRFTMYTTSSKDQSSDRTSLSSVGAQDSESTSLTDEDVCHELEGPISSQETSATSGTKRIDLSRISLESSASLEGSLSKFALPGKSEVTSSFNASNTNIFQNYAMEVLISSCSRCRTCDCLVHDEEIMAGWTADDSNLNTTCPFCGNIFLPFLNIEIRDLRRPGRYFLKSSPSTENMHFPSSISSQTRQSCISTSASGLDTSALSVQGNFDLNSKSKLQENFCTRSIQIPANRSKTAMSKCPIFPMARSISTSGPLDKEDTGRQKLISTGSLPATLQGATDSLGLEWHLPSPDPVTVPYLSPLVVWKELESLLENEGDHAITVADFVDHHPIVFWNLVWYFRRLDLPSNLPGLILSSEHCNKYSKIPRHCMSEDSKYVLIQMLWDNMKLHQDPGQPLYILWNAHTQKYPMVHLLQKSDNSFNQELLKSMVKSIKMNDVYGPMSQILETLNKCPHFKRQRSLYREILFLSLVALGRENIDIDAFDKEYKMAYDRLTPSQVKSTHNCDRPPSTGVMECRKTFGEPYL", "length": 1863 }, "evidence": [ { "id": "A0A8V0Z3U9", "url": "https://omabrowser.org/oma/group/A0A8V0Z3U9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of Rab protein signal transduction", "id": "GO:0032483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032483", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9" } ], "pmid": "" }, { "name": "ESCRT I complex", "id": "GO:0000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3U9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1035, "end_pos": 1037, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1210, "end_pos": 1212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1388, "end_pos": 1390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1484, "end_pos": 1486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1581, "end_pos": 1583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1756, "end_pos": 1758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 908, "end_pos": 910, "annotation": "n_glycosylation_sequon" }, { "start_pos": 974, "end_pos": 976, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9" }, { "id": "PS51498", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51498" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MABP", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 199, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z3U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3U9" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 191, "end_pos": 639, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1193, 1645 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1035, "end_pos": 1037 }, { "start_pos": 1210, "end_pos": 1212 }, { "start_pos": 129, "end_pos": 131 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 1388, "end_pos": 1390 }, { "start_pos": 1484, "end_pos": 1486 }, { "start_pos": 149, "end_pos": 151 }, { "start_pos": 1581, "end_pos": 1583 }, { "start_pos": 1756, "end_pos": 1758 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 78, "end_pos": 80 }, { "start_pos": 908, "end_pos": 910 }, { "start_pos": 974, "end_pos": 976 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3W6-1", "uniprot_ac": "A0A8V0Z3W6", "uniprot_id": "A0A8V0Z3W6_CHICK", "mass": { "chemical_mass": 76676.0, "monoisotopic_mass": 76676.0 }, "refseq": {}, "gene_names": [ { "name": "CLIP4", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6" } ] } ], "protein_names": [ { "name": "CAP-Gly domain containing linker protein family member 4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CLIP4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6", "locus": { "chromosome": "3", "start_pos": 8670198, "end_pos": 8710708, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017660", "url": "https://www.ensembl.org/id/ENSGALG00010017660" } ] } } ], "crossref": [ { "id": "A0A8V0Z3W6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3W6", "database": "AlphaFoldDB", "categories": [] }, { "id": "428556", "url": "https://www.ncbi.nlm.nih.gov/gene/428556", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3V3", "url": "https://www.orthodb.org/?gene=A0A8V0Z3V3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3V7", "url": "https://www.orthodb.org/?gene=A0A8V0Z3V7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3W1", "url": "https://www.orthodb.org/?gene=A0A8V0Z3W1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3W6", "url": "https://www.orthodb.org/?gene=A0A8V0Z3W6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18916", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18916", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18916:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18916:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z3V3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3V7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3W1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTIEGIPEPSFEGDSFTERDRFLFPSSETSVTFSVAAAPMPSDCEFSFFDPNDAACQEILFNPKTSVSELFAILRQWVPQVQQNIDIIGNEIIKRGCNVNDRDGLTDMTLLHYTCKSGAHGIGDVETAVKFAMQLIDLGADSSLRSRWTNMNALHYAAYFDVPELISVILKNAKPKDVDATCSDFDFGTALHIAAFNLCTGAVKCLLEHGANPAFRNDKGQIPVDVVPDPVDMPLEMADAAASAKEIKQILLDAMPLSCDISKAMITNYDHITGKAMLLSLGLKLGDRVIIAGQKVGTLRFCGTTEFASGQWAGVELDEAEGKNNGSVGKVQYFKCAPKRGIFAPLSKISKAYDHKKSSVRSSSTRSSPLIKSKKIDVTHITSKVNSGINKSRKPSGSENKFVTVNRGKTVPAKGGFPEYSSSSSSTTSLEGKQNYTKKRNSPGSNKKPLTRVSSASSRISAGLYSSSPAPRKTPYDERGIQVGDRVLVVGQRTGTVRFCGTTKFAPGFWCGIELDKPHGKNDGSVGGVQYFSCLPRYGIFAPPSRVQRLTGSMDSLAETSSKINHTFPGFRRSLSTTSASSQREISRRNSFVRSKSSVSRHSWSHPSTATTEGLVKLHEGSQVLLTSSNEMGTISHLQGSGVAGDPCHLTFIYLTKGSVAQTPGQTKEDKKILLQRTYIITLWSQLTEWAHNFHGSETGRSGCRH", "length": 706, "header": "tr|A0A8V0Z3W6-1|A0A8V0Z3W6_CHICK Isoform 1 of CAP-Gly domain containing linker protein family member 4 OS=Gallus gallus OX=9031 GN=CLIP4 PE=4 SV=1 CANONICAL=A0A8V0Z3W6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6/entry#A0A8V0Z3V3-1", "sequence": { "sequence": "MTIEGIPEPSFEGDSFTERDRFLFPSSETSVTFSVAAAPMPSDCEFSFFDPNDAACQEILFNPKTSVSELFAILRQWVPQVQQNIDIIGNEIIKRGCNVNDRDGLTDMTLLHYTCKSGAHGIGDVETAVKFAMQLIDLGADSSLRSRWTNMNALHYAAYFDVPELISVILKNAKPKDVDATCSDFDFGTALHIAAFNLCTGAVKCLLEHGANPAFRNDKGQIPVDVVPDPVDMPLEMADAAASAKEIKQILLDAMPLSCDISKAMITNYDHITGKAMLLSLGLKLGDRVIIAGQKVGTLRFCGTTEFASGQWAGVELDEAEGKNNGSVGKVQYFKCAPKRGIFAPLSKISKAYDHKKSSVRSSSTRSSPLIKSKKIDVTHITSKVNSGINKSRKPSGSENKFVTVNRGKTVPAKGGFPEYSSSSSSTTSLEGKQNYTKKRNSPGSNKKPLTRVSSASSRISAGLYSSSPAPRKTPYDERGIQVGDRVLVVGQRTGTVRFCGTTKFAPGFWCGIELDKPHGKNDGSVGGVQYFSCLPRYGIFAPPSRVQRLTGSMDSLAETSSKINHTFPGFRRSLSTTSASSQREISRRNSFVRSKSSVSRHSWSHPSTATTEGLVKLHEGSQVLLTSSNEMGTIRYIGPTDFAPGIWLGLELRSAKGKNDGSVGEKRYFTCKQNHGVLVRPSRVTYRGISGAKLVDDIC", "length": 700, "header": "tr|A0A8V0Z3V3-1|A0A8V0Z3W6_CHICK Computationally mapped isoform of CAP-Gly domain containing linker protein family member 4 OS=Gallus gallus OX=9031 GN=CLIP4 PE=4 SV=1 CANONICAL=A0A8V0Z3W6-1" }, "locus": { "chromosome": "3", "start_pos": 8707158, "end_pos": 8688640, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042683.1", "url": "https://www.ensembl.org/id/ENSGALT00010042683.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025173.1", "url": "https://www.ensembl.org/id/ENSGALP00010025173.1" } ] } }, { "isoform_ac": "A0A8V0Z3V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6/entry#A0A8V0Z3V7-1", "sequence": { "sequence": "MTIEGIPEPSFEGDSFTERDRFLFPSSETSVTFSVAAAPMPSDCAEFSFFDPNDAACQEILFNPKTSVSELFAILRQWVPQVQQNIDIIGNEIIKRGCNVNDRDGLTDMTLLHYTCKSGAHGIGDVETAVKFAMQLIDLGADSSLRSRWTNMNALHYAAYFDVPELISVILKNAKPKDVDATCSDFDFGTALHIAAFNLCTGAVKCLLEHGANPAFRNDKGQIPVDVVPDPVDMPLEMADAAASAKEIKQILLDAMPLSCDISKAMITNYDHITGKAMLLSLGLKLGDRVIIAGQKVGTLRFCGTTEFASGQWAGVELDEAEGKNNGSVGKVQYFKCAPKRGIFAPLSKISKAYDHKKSSVRSSSTRSSPLIKSKKIDVTHITSKVNSGINKSRKPSGSENKFVTVNRGKTVPAKGGFPEYSSSSSSTTSLEGKQNYTKKRNSPGSNKKPLTRVSSASSRISAGLYSSSPAPRKTPYDERGIQVGDRVLVVGQRTGTVRFCGTTKFAPGFWCGIELDKPHGKNDGSVGGVQYFSCLPRYGIFAPPSRVQRLTGSMDSLAETSSKINHTFPGFRRSLSTTSASSQREISRRNSFVRSKSSVSRHSWSHPSTATTEGLVKLHEGSQVLLTSSNEMGTIRGLPAAVL", "length": 644, "header": "tr|A0A8V0Z3V7-1|A0A8V0Z3V7_CHICK Computationally mapped isoform of CAP-Gly domain containing linker protein family member 4 OS=Gallus gallus OX=9031 GN=CLIP4 PE=4 SV=1 CANONICAL=A0A8V0Z3W6-1" }, "locus": { "chromosome": "3", "start_pos": 8707158, "end_pos": 8686901, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042688.1", "url": "https://www.ensembl.org/id/ENSGALT00010042688.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025178.1", "url": "https://www.ensembl.org/id/ENSGALP00010025178.1" } ] } }, { "isoform_ac": "A0A8V0Z3W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6/entry#A0A8V0Z3W1-1", "sequence": { "sequence": "MTIEGIPEPSFEGDSFTERDRFLFPSSETSVTFSVAAAPMPSDCEFSFFDPNDAACQEILFNPKTSVSELFAILRQWVPQVQQNIDIIGNEIIKRGCNVNDRDGLTDMTLLHYTCKSGAHGIGDVETAVKFAMQLIDLGADSSLRSRWTNMNALHYAAYFDVPELISVILKNAKPKDVDATCSDFDFGTALHIAAFNLCTGAVKCLLEHGANPAFRNDKGQIPVDVVPDPVDMPLEMADAAASAKEIKQILLDAMPLSCDISKAMITNYDHITGKAMLLSLGLKLGDRVIIAGQKVGTLRFCGTTEFASGQWAGVELDEAEGKNNGSVGKVQYFKCAPKRGIFAPLSKISKAYDHKKSSVRSSSTRSSPLIKSKKIDVTHITSKVNSGINKSRKPSGSENKFVTVNRGKTVPAKGGFPEYSSSSSSTTSLEGKQNYTKKRNSPGSNKKPLTRVSSASSRISAGLYSSSPAPRKTPYDERGIQVGDRVLVVGQRTGTVRFCGTTKFAPGFWCGIELDKPHGKNDGSVGGVQYFSCLPRYGIFAPPSRVQRLTGSMDSLAETSSKINHTFPGFRRSLSTTSASSQREISRRNSFVRSKSSVSRHSWSHPSTATTEGLVKLHEGSQVLLTSSNEMGTIRVC", "length": 638, "header": "tr|A0A8V0Z3W1-1|A0A8V0Z3W1_CHICK Computationally mapped isoform of CAP-Gly domain containing linker protein family member 4 OS=Gallus gallus OX=9031 GN=CLIP4 PE=4 SV=1 CANONICAL=A0A8V0Z3W6-1" }, "locus": { "chromosome": "3", "start_pos": 8707158, "end_pos": 8684447, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042693.1", "url": "https://www.ensembl.org/id/ENSGALT00010042693.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025183.1", "url": "https://www.ensembl.org/id/ENSGALP00010025183.1" } ] } }, { "isoform_ac": "A0A8V0Z3W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6/entry#A0A8V0Z3W6-1", "sequence": { "sequence": "MTIEGIPEPSFEGDSFTERDRFLFPSSETSVTFSVAAAPMPSDCEFSFFDPNDAACQEILFNPKTSVSELFAILRQWVPQVQQNIDIIGNEIIKRGCNVNDRDGLTDMTLLHYTCKSGAHGIGDVETAVKFAMQLIDLGADSSLRSRWTNMNALHYAAYFDVPELISVILKNAKPKDVDATCSDFDFGTALHIAAFNLCTGAVKCLLEHGANPAFRNDKGQIPVDVVPDPVDMPLEMADAAASAKEIKQILLDAMPLSCDISKAMITNYDHITGKAMLLSLGLKLGDRVIIAGQKVGTLRFCGTTEFASGQWAGVELDEAEGKNNGSVGKVQYFKCAPKRGIFAPLSKISKAYDHKKSSVRSSSTRSSPLIKSKKIDVTHITSKVNSGINKSRKPSGSENKFVTVNRGKTVPAKGGFPEYSSSSSSTTSLEGKQNYTKKRNSPGSNKKPLTRVSSASSRISAGLYSSSPAPRKTPYDERGIQVGDRVLVVGQRTGTVRFCGTTKFAPGFWCGIELDKPHGKNDGSVGGVQYFSCLPRYGIFAPPSRVQRLTGSMDSLAETSSKINHTFPGFRRSLSTTSASSQREISRRNSFVRSKSSVSRHSWSHPSTATTEGLVKLHEGSQVLLTSSNEMGTISHLQGSGVAGDPCHLTFIYLTKGSVAQTPGQTKEDKKILLQRTYIITLWSQLTEWAHNFHGSETGRSGCRH", "length": 706, "header": "tr|A0A8V0Z3W6-1|A0A8V0Z3W6_CHICK Isoform 1 of CAP-Gly domain containing linker protein family member 4 OS=Gallus gallus OX=9031 GN=CLIP4 PE=4 SV=1 CANONICAL=A0A8V0Z3W6-1" }, "locus": { "chromosome": "3", "start_pos": 8707158, "end_pos": 8670736, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042698.1", "url": "https://www.ensembl.org/id/ENSGALT00010042698.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025188.1", "url": "https://www.ensembl.org/id/ENSGALP00010025188.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6" } ], "pmid": "" }, { "name": "microtubule plus-end", "id": "GO:0035371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035371", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule plus-end binding", "id": "GO:0051010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051010", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3W6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W6" }, { "id": "PS50245", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50245" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CAP-Gly", "eco_id": "ECO_0000259", "start_pos": 303, "end_pos": 345, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 325, "end_pos": 327 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 565, "end_pos": 567 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z3W8-1", "uniprot_ac": "A0A8V0Z3W8", "uniprot_id": "A0A8V0Z3W8_CHICK", "mass": { "chemical_mass": 228531.0, "monoisotopic_mass": 228531.0 }, "refseq": {}, "gene_names": [ { "name": "NCKAP5", "type": "recommended", "evidence": [ { "id": "A0A8V0Z3W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8" } ] } ], "protein_names": [ { "name": "NCK associated protein 5", "type": "synonym", "evidence": [ { "id": "A0A8V0Z3W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NCKAP5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8", "locus": { "chromosome": "7", "start_pos": 29401378, "end_pos": 29742314, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019443", "url": "https://www.ensembl.org/id/ENSGALG00010019443" } ] } } ], "crossref": [ { "id": "IPR026163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3W8", "url": "https://www.orthodb.org/?gene=A0A8V0Z3W8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZB78", "url": "https://www.orthodb.org/?gene=A0A8V0ZB78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZH64", "url": "https://www.orthodb.org/?gene=A0A8V0ZH64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21740:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21740:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z3W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB78", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZB78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH64", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZH64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH64-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERKRLLQKREIGKRLSLDSSLVDYMDSNKYIEHLVTQLEEQRWNLWREKLSVARLQREVAQSKSEGTMREKLIHELEEERHLRLESEKRLREVTLESERNRAQMRGLQEQFSRMEETVRNLLQSQGSPGQNGEGTVNIMKAYQEKLSEDSRKCKEVMEKNHTAVDEDSRNESNSTEEEKEKTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECIKLKTRVFDLEQQNRTLSVLFQQRVKPASDLLLQKLHSRILDLSSGDLLSEVDRNRSSVPSRPADAQIHECQQNVKSTIPVLKCHSQLNVTGPSRLYPRSSCSSSELSLSSACSEYSSGSSYTWNDGKTCSKRSSVSWDKRISIGSSLPSNLSSPADDLPPTRIKENHILEGLKKLQRQKVLLESPSVIPKWGYKDCMNSNEGIYSPGVKCGSHHEQTHCKPMEIGSSCIEHNKTFSYDSDSHDDADDDSSSLLLLQEVPSKDCRIYCNKLTHSVSDSLFHWDPNRKHLPERSSYFNSKERPEKLTSFVSGFQAEVESCTRTKLPDLQLDQSHANIGWKDLNFQLSDTDDNEVLDELHIESSDEKSPSDLLATPFTEKYTKNSDVLIVTENSQFISSDKEERQTSAHSDIRPKTCNFIKQQKVIKKTSSEECITVIFDAEDGEPIEFSSHQTGVVTVTRNEISVNQPESRSSAEYTELIPQGIANLQAGTNARDYSVLEGPEDKTKKQTLEDNTGNKNMVVTTTCSESSPCGRIILQNAPRQKLVKPVYDVSYKTNSSSIVHAGINQKPILTKIPSRGKFSPQKNKMTESEEAPVATSVTPATLEKSPALPPVKLSRLKKAQSPPRNFDSKVDFQVPKPPAHPLPSSKRPSRGNGTKYPKSQSPASPLLPQHLIEPTDYGEPPTRDSNHDLATVEARSPSPPLPPGRSTSLLIRPDYAHSQPAAVKLGGAVPGETAKNILKSSPLKGTANSGIHNQSSHDMQAKSVSSGAKIELSYLQENSEAIMQNKCISQQPHSACQGLSKVSTKQVCLKNTNQMGLHRNREFLSMDSQTGRSIPLGPSLETTSQEVHSSKKDISSDSGVDQPQKMPNILPATPQCHTASVSEPLLSQVNNSPLSTLFHGSDTANATQNSNEKGVKTRLPVGLKLFVKSPQLLRKSSTVPGKQEKDSINAASKSHVSTSKHKQNERVATKGAIDAELKDSKSDTEIKDNFSLRLSVDTASPRSHENGSLVVDRVDELESKLVKRSFSSSNKSHLKPALGMNGAKARSQSFSVHTGEKSSTLVTESLGKVRTQIITNTSDRGNSLTRQNSAMEGLQIKAIPGSGATQETLSNTSKNTENAYSRQGSLGSNSNNQHGSPSKLPFRSSPKVDLFRNTSKYDGNKSFSMKDARSLSAQSEKSSENLKHEALNKKSVLPAELELDASATVSSKQISSIHSLGGIKCPHKLEAIKSQRQQMSLKLAEAPQVTDVFSSPALQPTIEEKVMLCIQENVQKGQEQNKSPTVETKQKTGPSIASWFGFRKSKLPALSSRKPDVPKTKVEKKEPRVSGFGIKQSKLERRKEKKQTEQHCEVENEINRKTDSSDFLDDAMEFKILKPSRNTSGKIGCEQLRGSSIATYSSKDSFMKELLNRSVSKGSSQGSSLHSNSISSQGNHKKNSNTKADMEIQNQTLANVVTENLQEEEEDTMTRTTCQSHVIESCCQMRTLDSGIGTFPLPDSGNRSAGRHVSKQELTLETEALAPSEQVLLSAPSVKAKTLEREVPSTATSQESVESMISHSTSDPAMTAKGIRPFQSRLPKPDSSGIINLAKQSEQEPSSVTSTSLELTEETVENRKVLSDWTTKKTTEAKDRTLRVCTYSASSSDAEPEPEYGTNYFQTAEEMLVGLTKSNKPAEQEKQKQRKSVLGNPMSILDLYQHSLYGHFGEDGPEQLTHFSLIEQLSEPSGKDSKDKESPSNLKQTEETKEDPQTRLSKISLESLNKFNSNNVLLLEKEKNCLNKAEGQKEESGKKEASSLNSSDRQDMDNLESLSDSLYDSFSSCASQGSNDV", "length": 2063, "header": "tr|A0A8V0Z3W8-1|A0A8V0Z3W8_CHICK Isoform 1 of NCK associated protein 5 OS=Gallus gallus OX=9031 GN=NCKAP5 PE=4 SV=1 CANONICAL=A0A8V0Z3W8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8/entry#A0A8V0Z3W8-1", "sequence": { "sequence": "MERKRLLQKREIGKRLSLDSSLVDYMDSNKYIEHLVTQLEEQRWNLWREKLSVARLQREVAQSKSEGTMREKLIHELEEERHLRLESEKRLREVTLESERNRAQMRGLQEQFSRMEETVRNLLQSQGSPGQNGEGTVNIMKAYQEKLSEDSRKCKEVMEKNHTAVDEDSRNESNSTEEEKEKTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECIKLKTRVFDLEQQNRTLSVLFQQRVKPASDLLLQKLHSRILDLSSGDLLSEVDRNRSSVPSRPADAQIHECQQNVKSTIPVLKCHSQLNVTGPSRLYPRSSCSSSELSLSSACSEYSSGSSYTWNDGKTCSKRSSVSWDKRISIGSSLPSNLSSPADDLPPTRIKENHILEGLKKLQRQKVLLESPSVIPKWGYKDCMNSNEGIYSPGVKCGSHHEQTHCKPMEIGSSCIEHNKTFSYDSDSHDDADDDSSSLLLLQEVPSKDCRIYCNKLTHSVSDSLFHWDPNRKHLPERSSYFNSKERPEKLTSFVSGFQAEVESCTRTKLPDLQLDQSHANIGWKDLNFQLSDTDDNEVLDELHIESSDEKSPSDLLATPFTEKYTKNSDVLIVTENSQFISSDKEERQTSAHSDIRPKTCNFIKQQKVIKKTSSEECITVIFDAEDGEPIEFSSHQTGVVTVTRNEISVNQPESRSSAEYTELIPQGIANLQAGTNARDYSVLEGPEDKTKKQTLEDNTGNKNMVVTTTCSESSPCGRIILQNAPRQKLVKPVYDVSYKTNSSSIVHAGINQKPILTKIPSRGKFSPQKNKMTESEEAPVATSVTPATLEKSPALPPVKLSRLKKAQSPPRNFDSKVDFQVPKPPAHPLPSSKRPSRGNGTKYPKSQSPASPLLPQHLIEPTDYGEPPTRDSNHDLATVEARSPSPPLPPGRSTSLLIRPDYAHSQPAAVKLGGAVPGETAKNILKSSPLKGTANSGIHNQSSHDMQAKSVSSGAKIELSYLQENSEAIMQNKCISQQPHSACQGLSKVSTKQVCLKNTNQMGLHRNREFLSMDSQTGRSIPLGPSLETTSQEVHSSKKDISSDSGVDQPQKMPNILPATPQCHTASVSEPLLSQVNNSPLSTLFHGSDTANATQNSNEKGVKTRLPVGLKLFVKSPQLLRKSSTVPGKQEKDSINAASKSHVSTSKHKQNERVATKGAIDAELKDSKSDTEIKDNFSLRLSVDTASPRSHENGSLVVDRVDELESKLVKRSFSSSNKSHLKPALGMNGAKARSQSFSVHTGEKSSTLVTESLGKVRTQIITNTSDRGNSLTRQNSAMEGLQIKAIPGSGATQETLSNTSKNTENAYSRQGSLGSNSNNQHGSPSKLPFRSSPKVDLFRNTSKYDGNKSFSMKDARSLSAQSEKSSENLKHEALNKKSVLPAELELDASATVSSKQISSIHSLGGIKCPHKLEAIKSQRQQMSLKLAEAPQVTDVFSSPALQPTIEEKVMLCIQENVQKGQEQNKSPTVETKQKTGPSIASWFGFRKSKLPALSSRKPDVPKTKVEKKEPRVSGFGIKQSKLERRKEKKQTEQHCEVENEINRKTDSSDFLDDAMEFKILKPSRNTSGKIGCEQLRGSSIATYSSKDSFMKELLNRSVSKGSSQGSSLHSNSISSQGNHKKNSNTKADMEIQNQTLANVVTENLQEEEEDTMTRTTCQSHVIESCCQMRTLDSGIGTFPLPDSGNRSAGRHVSKQELTLETEALAPSEQVLLSAPSVKAKTLEREVPSTATSQESVESMISHSTSDPAMTAKGIRPFQSRLPKPDSSGIINLAKQSEQEPSSVTSTSLELTEETVENRKVLSDWTTKKTTEAKDRTLRVCTYSASSSDAEPEPEYGTNYFQTAEEMLVGLTKSNKPAEQEKQKQRKSVLGNPMSILDLYQHSLYGHFGEDGPEQLTHFSLIEQLSEPSGKDSKDKESPSNLKQTEETKEDPQTRLSKISLESLNKFNSNNVLLLEKEKNCLNKAEGQKEESGKKEASSLNSSDRQDMDNLESLSDSLYDSFSSCASQGSNDV", "length": 2063, "header": "tr|A0A8V0Z3W8-1|A0A8V0Z3W8_CHICK Isoform 1 of NCK associated protein 5 OS=Gallus gallus OX=9031 GN=NCKAP5 PE=4 SV=1 CANONICAL=A0A8V0Z3W8-1" }, "locus": { "chromosome": "7", "start_pos": 29723995, "end_pos": 29402561, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046987.1", "url": "https://www.ensembl.org/id/ENSGALT00010046987.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027922.1", "url": "https://www.ensembl.org/id/ENSGALP00010027922.1" } ] } }, { "isoform_ac": "A0A8V0ZB78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8/entry#A0A8V0ZB78-1", "sequence": { "sequence": "MEREKLIHELEEERHLRLESEKRLREVTLESERNRAQMRGLQEQFSRMEETVRNLLQSQGSPGQNGEGTVNIMKAYQEKLSEDSRKCKEVMEKNHTAVDEDSRNESNSTEEEKEKTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECIKLKTRVFDLEQQNRTLSVLFQQRVKPASDLLLQKLHSRILDLSSGDLLSEVDRNRSSVPSRPADAQIHECQQNVKSTIPVLKCHSQLNVTGPSRLYPRSSCSSSELSLSSACSEYSSGSSYTWNDGKTCSKRSSVSWDKRISIGSSLPSNLSSPADDLPPTRIKENHILEGLKKLQRQKVLLESPSVIPKWGYKDCMNSNEGIYSPGVKCGSHHEQTHCKPMEIGSSCIEHNKTFSYDSDSHDDADDDSSSLLLLQEVPSKDCRIYCNKLTHSVSDSLFHWDPNRKHLPERSSYFNSKERPEKLTSFVSGFQAEVESCTRTKLPDLQLDQSHANIGWKDLNFQLSDTDDNEVLDELHIESSDEKSPSDLLATPFTEKYTKNSDVLIVTENSQFISSDKEERQTSAHSDIRPKTCNFIKQQKVIKKTSSEECITVIFDAEDGEPIEFSSHQTGVVTVTRNEISVNQPESRSSAEYTELIPQGIANLQAGTNARDYSVLEGPEDKTKKQTLEDNTGNKNMVVTTTCSESSPCGRIILQNAPRQKLVKPVYDVSYKTNSSSIVHAGINQKPILTKIPSRGKFSPQKNKMTESEEAPVATSVTPATLEKSPALPPVKLSRLKKAQSPPRNFDSKVDFQVPKPPAHPLPSSKRPSRGNGTKYPKSQSPASPLLPQHLIEPTDYGEPPTRDSNHDLATVEARSPSPPLPPGRSTSLLIRPDYAHSQPAAVKLGGAVPGETAKNILKSSPLKGTANSGIHNQSSHDMQAKSVSSGAKIELSYLQENSEAIMQNKCISQQPHSACQGLSKVSTKQVCLKNTNQMGLHRNREFLSMDSQTGRSIPLGPSLETTSQEVHSSKKDISSDSGVDQPQKMPNILPATPQCHTASVSEPLLSQVNNSPLSTLFHGSDTANATQNSNEKGVKTRLPVGLKLFVKSPQLLRKSSTVPGKQEKDSINAASKSHVSTSKHKQNERVATKGAIDAELKDSKSDTEIKDNFSLRLSVDTASPRSHENGSLVVDRVDELESKLVKRSFSSSNKSHLKPALGMNGAKARSQSFSVHTGEKSSTLVTESLGKVRTQIITNTSDRGNSLTRQNSAMEGLQIKAIPGSGATQETLSNTSKNTENAYSRQGSLGSNSNNQHGSPSKLPFRSSPKVDLFRNTSKYDGNKSFSMKDARSLSAQSEKSSENLKHEALNKKSVLPAELELDASATVSSKQISSIHSLGGIKCPHKLEAIKSQRQQMSLKLAEAPQVTDVFSSPALQPTIEEKVMLCIQENVQKGQEQNKSPTVETKQKTGPSIASWFGFRKSKLPALSSRKPDVPKTKVEKKEPRVSGFGIKQSKLERRKEKKQTEQHCEVENEINRKTDSSDFLDDAMEFKILKPSRNTSGKIGCEQLRGSSIATYSSKDSFMKELLNRSVSKGSSQGSSLHSNSISSQGNHKKNSNTKADMEIQNQTLANVVTENLQEEEEDTMTRTTCQSHVIESCCQMRTLDSGIGTFPLPDSGNRSAGRHVSKQELTLETEALAPSEQVLLSAPSVKAKTLEREVPSTATSQESVESMISHSTSDPAMTAKGIRPFQSRLPKPDSSGIINLAKQSEQEPSSVTSTSLELTEETVENRKVLSDWTTKKTTEAKDRTLRVCTYSASSSDAEPEPEYGTNYFQTAEEMLVGLTKSNKPAEQEKQKQRKSVLGNPMSILDLYQHSLYGHFGEDGPEQLTHFSLIEQLSEPSGKDSKDKESPSNLKQTEETKEDPQTRLSKISLESLNKFNSNNVLLLEKEKNCLNKAEGQKEESGKKEASSLNSSDRQDMDNLESLSDSLYDSFSSCASQGSNDV", "length": 1996, "header": "tr|A0A8V0ZB78-1|A0A8V0Z3W8_CHICK Computationally mapped isoform of NCK associated protein 5 OS=Gallus gallus OX=9031 GN=NCKAP5 PE=4 SV=1 CANONICAL=A0A8V0Z3W8-1" }, "locus": { "chromosome": "7", "start_pos": 29628743, "end_pos": 29402561, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046983.1", "url": "https://www.ensembl.org/id/ENSGALT00010046983.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027920.1", "url": "https://www.ensembl.org/id/ENSGALP00010027920.1" } ] } }, { "isoform_ac": "A0A8V0ZH64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8/entry#A0A8V0ZH64-1", "sequence": { "sequence": "MERKRLLQKREIGKRLSLDSSLVDYMDSNKYIEHLVTQLEEQRWNLWREKLSVARLQREVAQSKSEGTMREKLIHELEEERHLRLESEKRLREVTLESERNRAQMRGLQEQFSRMEETVRNLLQSQGSPGQNGEGTVNIMKAYQEKLSEDSRKCKEVMEKNHTAVDEDSRNESNSTEEEKEKTKLLLERLKALEAENSALALENENQREQYERCLDEVANQVVQALLTQKDLREECIKLKTRVFDLEQQNRTLSVLFQQRVKPASDLLLQKLHSRILDLSSGDLLSEVDRNRSSVPSRPADAQIHECQQNVKSTIPVLKCHSQLNVTGPSRLYPRSSCSSSELSLSSACSEYSSGSSYTWNDGKTCSKRSSVSWDKRISIGSSLPSNLSSPADDLPPTRIKENHILEGLKKLQRQKVLLESPSVIPKWGYKDCMNSNEGIYSPGVKCGSHHEQTHCKPMEIGSSCIEHNKTFSYDSDSHDDADDDSSSLLLLQEVPSKDCRIYCNKLTHSVSDSLFHWDPNRKHLPERSSYFNSKERPEKLTSFVSGFQAEVESCTRTKLPDLQLDQSHANIGWKDLNFQLSDTDDNEVLDELHIESSDEKSPSDLLATPFTEKYTKNSDVLIVTENSQFISSDKEERQTSAHSDIRPKTCNFIKQQKVIKKTSSEECITVIFDAEDGEPIEFSSHQTGVVTVTRNEISVNQPESRSSAEYTELIPQGIANLQAGTNARDYSVLEGPEDKTKKQTLEDNTGNKNMVVTTTCSESSPCGRIILQNAPRQKLVKPVYDVSYKTNSSSIVHAGINQKPILTKIPSRGKFSPQKNKMTESEEAPVATSVTPATLEKSPALPPVKLSRLKKAQSPPRNFDSKVDFQVPKPPAHPLPSSKRPSRGNGTKYPKSQSPASPLLPQHLIEPTDYGEPPTRDSNHDLATVEARSPSPPLPPGRSTSLLIRPDYAHSQPAAVKLGGAVPGETAKNILKSSPLKGTANSGIHNQSSHDMQAKSVSSGAKIELSYLQENSEAIMQNKCISQQPHSACQGLSKVSTKQVCLKNTNQMGLHRNREFLSMDSQTGRSIPLGPSLETTSQEVHSSKKDISSDSGVDQPQKMPNILPATPQCHTASVSEPLLSQVNNSPLSTLFHGSDTANATQNSNEKGVKTRLPVGLKLFVKSPQLLRKSSTVPGKQEKDSINAASKSHVSTSKHKQNERVATKGAIDAELKDSKSDTEIKDNFSLRLSVDTASPRSHENGSLVVDRVDELESKLVKRSFSSSNKSHLKPALGMNGAKARSQSFSVHTGEKSSTLVTESLGKVRTQIITNTSDRGNSLTRQNSAMEGLQIKAIPGSGATQETLSNTSKNTENAYSRQGSLGSNSNNQHGSPSKLPFRSSPKVDLFRNTSKYDGNKSFSMKDARSLSAQSEKSSENLKHEALNKKSVLPAELELDASATVSSKQISSIHSLGGIKCPHKLEAIKSQRQQMSLKLAEAPQVTDVFSSPALQPTIEEKVMLCIQENVQKGQEQNKSPTVETKQKTGPSIASWFGFRKSKLPALSSRKPDVPKTKVEKKEPRVSGFGIKQSKLERRKEKKQTEQHCEVENEINRKTDSSDFLDDAMEFKILKPSRNTSGKIGCEQLRGSSIATYSSKDSFMKELLNRSVSKGSSQGSSLHSNSISSQGNHKKNSNTKADMEIQNQTLANVVTENLQEEEEDTMTRTTCQSHVIESCCQMRTLDSGIGTFPLPDSGNRSAGRHVSKQELTLETEALAPSEQVLLSAPSVKAKTLEREVPSTATSQESVESMISHSTSDPAMTAKGIRPFQSRLPKPDSSGIINLAKQSEQEPSSVTSTSLELTEETVENRKVLSDWTTKKTTEAKDRTLRVCTYSASSSDAEPEPEYGTNYFQTAEEMLVGLTKSNKPAEQEKQKQRKSVLGNPMSILDLYQHSLYGHFGEDGPEQLTHFSLIEQLSEPSGKDSKDKESPSVKQVKLLSLLRAVEKQHAAESGSATRRVITFSIT", "length": 2004, "header": "tr|A0A8V0ZH64-1|A0A8V0Z3W8_CHICK Computationally mapped isoform of NCK associated protein 5 OS=Gallus gallus OX=9031 GN=NCKAP5 PE=4 SV=1 CANONICAL=A0A8V0Z3W8-1" }, "locus": { "chromosome": "7", "start_pos": 29723995, "end_pos": 29422419, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010046977.1", "url": "https://www.ensembl.org/id/ENSGALT00010046977.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027918.1", "url": "https://www.ensembl.org/id/ENSGALP00010027918.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 836, "start_aa": "Thr", "end_pos": 836, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr836", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule plus-end", "id": "GO:0035371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035371", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "microtubule depolymerization", "id": "GO:0007019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007019", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8" } ], "pmid": "" }, { "name": "microtubule bundle formation", "id": "GO:0001578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001578", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3W8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1128, "end_pos": 1130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1143, "end_pos": 1145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1227, "end_pos": 1229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1244, "end_pos": 1246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1268, "end_pos": 1270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1314, "end_pos": 1316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1349, "end_pos": 1351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1391, "end_pos": 1393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1398, "end_pos": 1400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1515, "end_pos": 1517, 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This record is derived from a genomic sequence (NC_052536.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_420982.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_420982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420982" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SCUBE2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9", "locus": { "chromosome": "5", "start_pos": 9193924, "end_pos": 9158744, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019483", "url": "https://www.ensembl.org/id/ENSGALG00010019483" } ] } } ], "crossref": [ { "id": "A0A8V0Z3Z9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z3Z9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423049", "url": "https://www.ncbi.nlm.nih.gov/gene/423049", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3Z0", "url": "https://www.orthodb.org/?gene=A0A8V0Z3Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z3Z9", "url": "https://www.orthodb.org/?gene=A0A8V0Z3Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24046", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24046", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24046:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24046:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12947", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12947", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5362798", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5362798", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_420982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_420982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z3Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQFNDVDECALGLDDCHPDAICQNTPKLYKCMCKVGYTGEGKKCEDIDECDNDFNGGCVHECFNIPGNYRCTCYDGFMLAHDGHNCLDTDECMFNNGGCQHVCVNTVGSYECRCKEGFFLSDNQHTCIHRSEEGMSCMNKDHGCAHICRETPKGGVACECRPGFELSKNQRSCILTCNHGNGGCQHTCDDADHGPICGCHPKYIMHTDGKTCLEREEAAVEIPEGNTTAGADVDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQFDGKTCKDIDECQSNNGGCDHFCKNTVGSFDCSCRKGFKLLTDEKSCQDIDECSFERTCDHTCINHPGTFECTCNKGYALYGFTHCGDINECSINNGGCQQLCVNTPGDYECLCHSNYKLHWNKKDCVEIKESFPDNMSPKVLLHCMKSGRSDRCFLSCSSDVRVVSGTQDAYTLACGSSSQLKKKQQNTNASTWLDISTIKISVTFKLNEGKCSLKKTEMFQEGLEQTIPERHNSVMESFHYVNLTCSSGKKVHGALSRLPATREIFITADFELETNQKEVTDTCDVRCARKKTEKRFRKTIRTLRKTVSRDQFRVRVSGMDHEVARKSLKLSEPQQSCGVGQMHVGSRCDQCSPGEYSSDGFKPCLPCPIGTYQPEAGRVSCFPCGGGLTTRHSSTSLFQDCETKVQCSPGHFYNTTTHRCIRCMVGTYQPEFGQNYCISCPGNTTTDYDGSTNITQCKNRQCGGELGDYTGYIESPNYPGDYPANTECTWNINPPPKRRILIVVPEIFLPIEDECGDYLVMRKSSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSAKGFQVPYVTYDEDYQELIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESREMFPRSFIRLLRSKVSRFLRPYK", "length": 931, "header": "tr|A0A8V0Z3Z9-1|A0A8V0Z3Z9_CHICK Isoform 1 of Signal peptide, CUB and EGF-like domain-containing protein 2 OS=Gallus gallus OX=9031 GN=SCUBE2 PE=4 SV=1 CANONICAL=A0A8V0Z3Z9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z3Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9/entry#A0A8V0Z3Z0-1", "sequence": { "sequence": "MRQFNDVDECALGLDDCHPDAICQNTPKLYKCMCKVGYTGEGKKCEDIDECDNDFNGGCVHECFNIPGNYRCTCYDGFMLAHDGHNCLDTDECMFNNGGCQHVCVNTVGSYECRCKEGFFLSDNQHTCIHRSEVTCNHGNGGCQHTCDDADHGPICGCHPKYIMHTDGKTCLEREEAAVEIPEGNTTAGADVDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQFDGKTCKDIDECQSNNGGCDHFCKNTVGSFDCSCRKGFKLLTDEKSCQDIDECSFERTCDHTCINHPGTFECTCNKGYALYGFTHCGDINECSINNGGCQQLCVNTPGDYECLCHSNYKLHWNKKDCVEIKESFPDNMSPKVLLHCMKSGRSDRCFLSCSSDVRVVSGTQDAYTLACGSSSQLKKKQQNTNASTWLDISTIKISVTFKLNEGKCSLKKTEMFQEGLEQTIPERHNSVMESFHYVNLTCSSGKKVHGALSRLPATREIFITADFELETNQKEVTDTCDVRCARKKTEKRFRKTIRTLRKTVSRDQFRVRVSGMDHEVARKSLKLSEPQQSCGVGQMHVGSRCDQCSPGEYSSDGFKPCLPCPIGTYQPEAGRVSCFPCGGGLTTRHSSTSLFQDCETKVQCSPGHFYNTTTHRCIRCMVGTYQPEFGQNYCISCPGNTTTDYDGSTNITQCKNRQCGGELGDYTGYIESPNYPGDYPANTECTWNINPPPKRRILIVVPEIFLPIEDECGDYLVMRKSSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSAKGFQVPYVTYDEDYQELIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESREMFPRSFIRLLRSKVSRFLRPYK", "length": 889, "header": "tr|A0A8V0Z3Z0-1|A0A8V0Z3Z9_CHICK Computationally mapped isoform of Signal peptide, CUB and EGF-like domain-containing protein 2 OS=Gallus gallus OX=9031 GN=SCUBE2 PE=4 SV=1 CANONICAL=A0A8V0Z3Z9-1" }, "locus": { "chromosome": "5", "start_pos": 9192920, "end_pos": 9159522, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047048.1", "url": "https://www.ensembl.org/id/ENSGALT00010047048.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027942.1", "url": "https://www.ensembl.org/id/ENSGALP00010027942.1" } ] } }, { "isoform_ac": "A0A8V0Z3Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9/entry#A0A8V0Z3Z9-1", "sequence": { "sequence": "MRQFNDVDECALGLDDCHPDAICQNTPKLYKCMCKVGYTGEGKKCEDIDECDNDFNGGCVHECFNIPGNYRCTCYDGFMLAHDGHNCLDTDECMFNNGGCQHVCVNTVGSYECRCKEGFFLSDNQHTCIHRSEEGMSCMNKDHGCAHICRETPKGGVACECRPGFELSKNQRSCILTCNHGNGGCQHTCDDADHGPICGCHPKYIMHTDGKTCLEREEAAVEIPEGNTTAGADVDKRVKRRLLMETCAVNNGGCDRTCKDTSTGVHCSCPVGFTLQFDGKTCKDIDECQSNNGGCDHFCKNTVGSFDCSCRKGFKLLTDEKSCQDIDECSFERTCDHTCINHPGTFECTCNKGYALYGFTHCGDINECSINNGGCQQLCVNTPGDYECLCHSNYKLHWNKKDCVEIKESFPDNMSPKVLLHCMKSGRSDRCFLSCSSDVRVVSGTQDAYTLACGSSSQLKKKQQNTNASTWLDISTIKISVTFKLNEGKCSLKKTEMFQEGLEQTIPERHNSVMESFHYVNLTCSSGKKVHGALSRLPATREIFITADFELETNQKEVTDTCDVRCARKKTEKRFRKTIRTLRKTVSRDQFRVRVSGMDHEVARKSLKLSEPQQSCGVGQMHVGSRCDQCSPGEYSSDGFKPCLPCPIGTYQPEAGRVSCFPCGGGLTTRHSSTSLFQDCETKVQCSPGHFYNTTTHRCIRCMVGTYQPEFGQNYCISCPGNTTTDYDGSTNITQCKNRQCGGELGDYTGYIESPNYPGDYPANTECTWNINPPPKRRILIVVPEIFLPIEDECGDYLVMRKSSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSAKGFQVPYVTYDEDYQELIEDIVRDGRLYASENHQEILKDKKLIKALFDVLAHPQNYFKYTAQESREMFPRSFIRLLRSKVSRFLRPYK", "length": 931, "header": "tr|A0A8V0Z3Z9-1|A0A8V0Z3Z9_CHICK Isoform 1 of Signal peptide, CUB and EGF-like domain-containing protein 2 OS=Gallus gallus OX=9031 GN=SCUBE2 PE=4 SV=1 CANONICAL=A0A8V0Z3Z9-1" }, "locus": { "chromosome": "5", "start_pos": 9192920, "end_pos": 9159522, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047058.1", "url": "https://www.ensembl.org/id/ENSGALT00010047058.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027947.1", "url": "https://www.ensembl.org/id/ENSGALP00010027947.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5362798", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5362798", "resource": "Reactome", "description": "Release of Hh-Np from the secreting cell" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z3Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 722, "end_pos": 724, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z3Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 741, "end_pos": 853, "start_aa": "Cys", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z3Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z3Z9" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 46, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 467, "end_pos": 469 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 693, "end_pos": 695 }, { "start_pos": 722, "end_pos": 724 }, { "start_pos": 732, "end_pos": 734 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z405-1", "uniprot_ac": "A0A8V0Z405", "uniprot_id": "A0A8V0Z405_CHICK", "mass": { "chemical_mass": 30178.0, "monoisotopic_mass": 30178.0 }, "refseq": {}, "gene_names": [ { "name": "NENF", "type": "recommended", "evidence": [ { "id": "A0A8V0Z405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z405" } ] } ], "protein_names": [ { "name": "Neudesin neurotrophic factor", "type": "synonym", "evidence": [ { "id": "A0A8V0Z405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z405/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z405", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z405" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NENF", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z405", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z405", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z405", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000009821", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000009821", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "421370", "url": "https://www.ncbi.nlm.nih.gov/gene/421370", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001199", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001199", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "VGYTAQR", "url": "https://omabrowser.org/oma/group/VGYTAQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z405", "url": "https://www.orthodb.org/?gene=A0A8V0Z405", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1P524", "url": "https://www.orthodb.org/?gene=F1P524", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10281", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10281", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10281:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10281:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00173", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00173", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z405", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z405", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z405-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z405-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P524", "url": "https://www.uniprot.org/uniprotkb/F1P524", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1P524-1", "url": "https://www.uniprot.org/uniprotkb/F1P524-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "SGGSRVNGRGAAVGAALVLRVLRAVPRVLPRRVLGSVSRSAKSTPGASRAQAQRAPVCAGPRLSGGLRAADTTTAPTRVRPSAEGTQICYSRITAERVTRLQPDRRGAPGLPCRGQRERSRPEAGGGATPCERAGERRRGWRHGGAAAAGRAADGRRGAGGGRAGAALQGSAARRDAGAAVHRARAGQIRRAAEFYGKGAPYNALVGKDSTRGVAKMSLDPADLTHDITGLTEEELKSLDDIFNNVYKAKYPIVGYTSRRILNEDGSPNLDFKPEDQPHFNIRDEF", "length": 286, "header": "tr|A0A8V0Z405-1|A0A8V0Z405_CHICK Isoform 1 of Neudesin neurotrophic factor OS=Gallus gallus OX=9031 GN=NENF PE=1 SV=1 CANONICAL=A0A8V0Z405-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z405-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z405/entry#A0A8V0Z405-1", "sequence": { "sequence": "SGGSRVNGRGAAVGAALVLRVLRAVPRVLPRRVLGSVSRSAKSTPGASRAQAQRAPVCAGPRLSGGLRAADTTTAPTRVRPSAEGTQICYSRITAERVTRLQPDRRGAPGLPCRGQRERSRPEAGGGATPCERAGERRRGWRHGGAAAAGRAADGRRGAGGGRAGAALQGSAARRDAGAAVHRARAGQIRRAAEFYGKGAPYNALVGKDSTRGVAKMSLDPADLTHDITGLTEEELKSLDDIFNNVYKAKYPIVGYTSRRILNEDGSPNLDFKPEDQPHFNIRDEF", "length": 286, "header": "tr|A0A8V0Z405-1|A0A8V0Z405_CHICK Isoform 1 of Neudesin neurotrophic factor OS=Gallus gallus OX=9031 GN=NENF PE=1 SV=1 CANONICAL=A0A8V0Z405-1" }, "locus": { "chromosome": "3", "start_pos": 21622131, "end_pos": 21618689, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047113.1", "url": "https://www.ensembl.org/id/ENSGALT00010047113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027957.1", "url": "https://www.ensembl.org/id/ENSGALP00010027957.1" } ] } }, { "isoform_ac": "F1P524-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z405/entry#F1P524-1", "sequence": { "sequence": "MAGRPLQAALLTAVAVLAAAERELRFKAPPPAETPVRLFTEPELARYDGQQEGQPIYLAVKGVVFDVTSGKEFYGKGAPYNALVGKDSTRGVAKMSLDPADLTHDITGLTEEELKSLDDIFNNVYKAKYPIVGYTSRRILNEDGSPNLDFKPEDQPHFNIRDEF", "length": 164, "header": "tr|F1P524-1|A0A8V0Z405_CHICK Computationally mapped isoform of Neudesin neurotrophic factor OS=Gallus gallus OX=9031 GN=NENF PE=1 SV=2 CANONICAL=A0A8V0Z405-1" }, "locus": { "chromosome": "3", "start_pos": 21621704, "end_pos": 21618689, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047117.1", "url": "https://www.ensembl.org/id/ENSGALT00010047117.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010027958.1", "url": "https://www.ensembl.org/id/ENSGALP00010027958.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A287B654-1", "protein_name": "Neudesin", "gene_name": "NENF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGPASRRRLAALALVLALAAGLRAAGPGQTPRPAERGPPVRLFTEEELARYGGDEEDQPIYMAVKGVVFDVTSGKEFYGRGAPYNALTGKDSTRGVAKMSLDPADLTHDTTGLTAEELQSLDDVFTRVYKAKYPIVGYTARRILNEDGSPNLDFKPEDQPHFDIKDEF", "length": 169 }, "evidence": [ { "id": "A0A8V0Z405", "url": "https://omabrowser.org/oma/group/A0A8V0Z405/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1JQA5-1", "protein_name": "Neudesin", "gene_name": "NENF", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGPAPGRRLVALALIVALAVGLPTAGAGQAPRPAERGPPVRLFTEEELARYGGEEEDQPIYMAVKGVVFDVTSGKEFYGRGAPYNALTGKDSTRGVAKMSLDPADLTHDTTGLTAEELESLDDVFTRVYKAKYPIVGYTARRILNEDGSPNLDFKPEDQPHFDIKDEF", "length": 169 }, "evidence": [ { "id": "A0A8V0Z405", "url": "https://omabrowser.org/oma/group/A0A8V0Z405/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6IUR5-1", "protein_name": "Neudesin", "gene_name": "Nenf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARPAPWWWLRPLAALALALALVRVPSARAGQMPRPAERGPPVRLFTEEELARYSGEEEDQPIYLAVKGVVFDVTSGKEFYGRGAPYNALAGKDSSRGVAKMSLDPADLTHDISGLTAKELEALDDIFSKVYKAKYPIVGYTARRILNEDGSPNLDFKPEDQPHFDIKDEF", "length": 171 }, "evidence": [ { "id": "A0A8V0Z405", "url": "https://omabrowser.org/oma/group/A0A8V0Z405/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CQ45-1", "protein_name": "Neudesin", "gene_name": "Nenf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARPAPWWRLRLLAALVLALALVPVPSAWAGQTPRPAERGPPVRLFTEEELARYGGEEEDQPIYLAVKGVVFDVTSGKEFYGRGAPYNALAGKDSSRGVAKMSLDPADLTHDTTGLTAKELEALDDVFSKVYKAKYPIVGYTARRILNEDGSPNLDFKPEDQPHFDIKDEF", "length": 171 }, "evidence": [ { "id": "A0A8V0Z405", "url": "https://omabrowser.org/oma/group/A0A8V0Z405/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UMX5-1", "protein_name": "Neudesin", "gene_name": "NENF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGPAPRRRLRPLAALALVLALAPGLPTARAGQTPRPAERGPPVRLFTEEELARYGGEEEDQPIYLAVKGVVFDVTSGKEFYGRGAPYNALTGKDSTRGVAKMSLDPADLTHDTTGLTAKELEALDEVFTKVYKAKYPIVGYTARRILNEDGSPNLDFKPEDQPHFDIKDEF", "length": 172 }, "evidence": [ { "id": "A0A8V0Z405", "url": "https://omabrowser.org/oma/group/A0A8V0Z405/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z405", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z405" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z405", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z405" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4I7-1", "uniprot_ac": "A0A8V0Z4I7", "uniprot_id": "A0A8V0Z4I7_CHICK", "mass": { "chemical_mass": 79896.0, "monoisotopic_mass": 79896.0 }, "refseq": {}, "gene_names": [ { "name": "ERI2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7" } ] } ], "protein_names": [ { "name": "ERI1 exoribonuclease family member 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ERI2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7", "locus": { "chromosome": "14", "start_pos": 15007851, "end_pos": 15012825, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017987", "url": "https://www.ensembl.org/id/ENSGALG00010017987" } ] } } ], "crossref": [ { "id": "A0A8V0Z4I7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4I7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06133", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06133", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR010666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051274", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051274", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z406", "url": "https://www.orthodb.org/?gene=A0A8V0Z406", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4I7", "url": "https://www.orthodb.org/?gene=A0A8V0Z4I7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23044", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23044", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23044:SF61", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23044:SF61", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00929", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00929", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06839", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06839", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z406", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z406", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z406-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z406-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATKRLARLLGMARSGRSGARSGGAAERRSEFDFLLVLDFESTCWRDARQRRPEISECCAGAARAVCWGCACGGCACPLAALDARAVMSPRGCRPPVALSLCSVPVEFPAVLLNAATGRIEAEFHTFVQPQEQPVLSEFCTTLTGVTQKQVDEGVPLHICLSQFLKWLQEIQKEKKILFSSDIPRNAIPEAKLCTFVTWTDWDLGVCLHYECKRKQLWKPDIFNSWIDLKATYRVRKAFYNRKPKGLSGALQDVGLAFVGREHSGLDDSRNTARLAWRLICDGCVLKITKSLDKSYPRKNLISRTLNTNSADKTLPGSSSSLETSRDRTCKANSLTERSHNGTVGIVVNSDVQPAGQATCSDCSTDMHVVSGSSSRTDLCEETRSSSTVSADRFPLLGCAQQSHSTLSPGIQQGLNSGHLMSTGRYSSPVCGSGLVLISTTISSVNTSSEDTGTRSDCLSLLTDWEDVALIPKSQSEPNPDYIQSKEDSSTVILTVSEENTVPKQSAAVSSGDQSLGKTLVPIEPPRSIIYKSPDTTIYNVGMVQKQTSNISAFKIPSAKVNAISSRSVLMRNSSIPSEVLKRKPTGPIALPPAKKQAFAIYQETMVSSDHALPLNLSKASRAVLSSTVNPNQSVTAVQNEKLTPPLCNCGQRAKRRYVSNAGPNHGKAFFCCPVGRREGSKRSCGYFKWENAFLKEKSRVITMNLDALTSLGTCPSTSGNSSNRCLFLRPSMRT", "length": 735, "header": "tr|A0A8V0Z4I7-1|A0A8V0Z4I7_CHICK Isoform 1 of ERI1 exoribonuclease family member 2 OS=Gallus gallus OX=9031 GN=ERI2 PE=4 SV=1 CANONICAL=A0A8V0Z4I7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z406-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7/entry#A0A8V0Z406-1", "sequence": { "sequence": "MATKRLARLLGMARSGRSGARSGGAAERRSEFDFLLVLDFESTCWRDARQRRPEIIEFPAVLLNAATGRIEAEFHTFVQPQEQPVLSEFCTTLTGVTQKQVDEGVPLHICLSQFLKWLQEIQKEKKILFSSDIPRNAIPEAKLCTFVTWTDWDLGVCLHYECKRKQLWKPDIFNSWIDLKATYRAFYNRKPKGLSGALQDVGLAFVGREHSARIFTVVAISVQLHEFFLSVGLDDSRNTARLAWRLICDGCVLKITKSLDKSYPRKNLISRTLNTNSADKTLPGSSSSLETSRDRTCKANSLTERSHNGTVGIVVNSDVQPAGQATCSDCSTDMHVVSGSSSRTDLCEETRSSSTVSADRFPLLGCAQQSHSTLSPGIQQGLNSGHLMSTGRYSSPVCGSGLVLISTTISSVNTSSEDTGTRSDCLSLLTDWEDVALIPKSQSEPNPDYIQSKEDSSTVILTVSEENTVPKQSAAVSSGDQSLGKTLVPIEPPRSIIYKSPDTTIYNVGMVQKQTSNISAFKIPSAKVNAISSRSVLMRNSSIPSEVLKRKPTGPIALPPAKKQAFAIYQETMVSSDHALPLNLSKASRAVLSSTVNPNQSVTAVQNEKLTPPLCNCGQRAKRRYVSNAGPNHGKAFFCCPVGRREGSKRSCGYFKWENAFLKEKSRVITMNLDALTSLGTCPSTSGNSSNRCLFLRPSMRT", "length": 702, "header": "tr|A0A8V0Z406-1|A0A8V0Z4I7_CHICK Computationally mapped isoform of ERI1 exoribonuclease family member 2 OS=Gallus gallus OX=9031 GN=ERI2 PE=4 SV=1 CANONICAL=A0A8V0Z4I7-1" }, "locus": { "chromosome": "14", "start_pos": 15012789, "end_pos": 15008338, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043454.1", "url": "https://www.ensembl.org/id/ENSGALT00010043454.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025831.1", "url": "https://www.ensembl.org/id/ENSGALP00010025831.1" } ] } }, { "isoform_ac": "A0A8V0Z4I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7/entry#A0A8V0Z4I7-1", "sequence": { "sequence": "MATKRLARLLGMARSGRSGARSGGAAERRSEFDFLLVLDFESTCWRDARQRRPEISECCAGAARAVCWGCACGGCACPLAALDARAVMSPRGCRPPVALSLCSVPVEFPAVLLNAATGRIEAEFHTFVQPQEQPVLSEFCTTLTGVTQKQVDEGVPLHICLSQFLKWLQEIQKEKKILFSSDIPRNAIPEAKLCTFVTWTDWDLGVCLHYECKRKQLWKPDIFNSWIDLKATYRVRKAFYNRKPKGLSGALQDVGLAFVGREHSGLDDSRNTARLAWRLICDGCVLKITKSLDKSYPRKNLISRTLNTNSADKTLPGSSSSLETSRDRTCKANSLTERSHNGTVGIVVNSDVQPAGQATCSDCSTDMHVVSGSSSRTDLCEETRSSSTVSADRFPLLGCAQQSHSTLSPGIQQGLNSGHLMSTGRYSSPVCGSGLVLISTTISSVNTSSEDTGTRSDCLSLLTDWEDVALIPKSQSEPNPDYIQSKEDSSTVILTVSEENTVPKQSAAVSSGDQSLGKTLVPIEPPRSIIYKSPDTTIYNVGMVQKQTSNISAFKIPSAKVNAISSRSVLMRNSSIPSEVLKRKPTGPIALPPAKKQAFAIYQETMVSSDHALPLNLSKASRAVLSSTVNPNQSVTAVQNEKLTPPLCNCGQRAKRRYVSNAGPNHGKAFFCCPVGRREGSKRSCGYFKWENAFLKEKSRVITMNLDALTSLGTCPSTSGNSSNRCLFLRPSMRT", "length": 735, "header": "tr|A0A8V0Z4I7-1|A0A8V0Z4I7_CHICK Isoform 1 of ERI1 exoribonuclease family member 2 OS=Gallus gallus OX=9031 GN=ERI2 PE=4 SV=1 CANONICAL=A0A8V0Z4I7-1" }, "locus": { "chromosome": "14", "start_pos": 15012789, "end_pos": 15008338, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043457.1", "url": "https://www.ensembl.org/id/ENSGALT00010043457.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025833.1", "url": "https://www.ensembl.org/id/ENSGALP00010025833.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000467", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7" } ], "pmid": "" }, { "name": "negative regulation of regulatory ncRNA-mediated heterochromatin formation", "id": "GO:0060906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060906", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 721, "end_pos": 723, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I7" }, { "id": "PS51999", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51999" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GRF-type", "eco_id": "ECO_0000259", "start_pos": 648, "end_pos": 694, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 341, "end_pos": 343 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 550, "end_pos": 552 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 616, "end_pos": 618 }, { "start_pos": 632, "end_pos": 634 }, { "start_pos": 721, "end_pos": 723 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z416-1", "uniprot_ac": "A0A8V0Z416", "uniprot_id": "A0A8V0Z416_CHICK", "mass": { "chemical_mass": 27551.0, "monoisotopic_mass": 27551.0 }, "refseq": { "ac": "XP_015149940", "name": "ras-related protein Rab-26", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149940" }, "gene_names": [ { "name": "RAB26", "type": "recommended", "evidence": [ { "id": "A0A8V0Z416", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ] }, { "name": "RAB26", "type": "synonym", "evidence": [ { "id": "XP_015149940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149940" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A8V0Z416", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z416", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-26", "type": "synonym", "evidence": [ { "id": "XP_015149940", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149940" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 17, 2018 this sequence version replaced XP_015149940.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149940" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "RAB26", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416", "locus": { "chromosome": "14", "start_pos": 6420700, "end_pos": 6399915, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017991", "url": "https://www.ensembl.org/id/ENSGALG00010017991" } ] } } ], "crossref": [ { "id": "A0A8V0Z416", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z416", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416554", "url": "https://www.ncbi.nlm.nih.gov/gene/416554", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416554", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416554", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QRSMKVP", "url": "https://omabrowser.org/oma/group/QRSMKVP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z416", "url": "https://www.orthodb.org/?gene=A0A8V0Z416", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47980", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47980", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149940", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z416-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRKKAARSKGGGSAPSAALPPPAAAAPRSPAPAPELPRNGGATSGRPSLSSSGEFYDLAFKVMLVGDSGVGKTCLLVRFKDGAFLAGSFISTVGIDFRNKVLTVDGVKVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQQDVVLMLLGNKVDSAQDRVVKREDGEKLAKEYGVPFMETSAKSGLNVELAFTAIAKELKHRSMKLPNEPKFKLHDYVKKEVRGSGCCRF", "length": 253, "header": "tr|A0A8V0Z416-1|A0A8V0Z416_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB26 PE=3 SV=1 CANONICAL=A0A8V0Z416-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z416-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416/entry#A0A8V0Z416-1", "sequence": { "sequence": "MSRKKAARSKGGGSAPSAALPPPAAAAPRSPAPAPELPRNGGATSGRPSLSSSGEFYDLAFKVMLVGDSGVGKTCLLVRFKDGAFLAGSFISTVGIDFRNKVLTVDGVKVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQQDVVLMLLGNKVDSAQDRVVKREDGEKLAKEYGVPFMETSAKSGLNVELAFTAIAKELKHRSMKLPNEPKFKLHDYVKKEVRGSGCCRF", "length": 253, "header": "tr|A0A8V0Z416-1|A0A8V0Z416_CHICK Isoform 1 of small monomeric GTPase OS=Gallus gallus OX=9031 GN=RAB26 PE=3 SV=1 CANONICAL=A0A8V0Z416-1" }, "locus": { "chromosome": "14", "start_pos": 6418163, "end_pos": 6399976, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043467.1", "url": "https://www.ensembl.org/id/ENSGALT00010043467.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025841.1", "url": "https://www.ensembl.org/id/ENSGALP00010025841.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "gga:416554", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416554", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B2K5-1", "protein_name": "small monomeric GTPase", "gene_name": "RAB26", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKKTPKSKGGSAPATSALPAAKGPRPVRPETARAGPEAPPNGPPQPGRSSLGGGGDIYDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKILDVDGMKVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKASFDSIQAWLTEIQEYAQRDVVLLLLGNKVDSAQERVVRREDGEQLAKEFGLPFMETSARTGLNVDLAFTAVAKELKQRLTKAPSEPRFQLHDYVKREGRGASCCRP", "length": 256 }, "evidence": [ { "id": "A0A8V0Z416", "url": "https://omabrowser.org/oma/group/A0A8V0Z416/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P51156-1", "protein_name": "Ras-related protein Rab-26", "gene_name": "Rab26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRKKTPKSKGGSVPAASTLPAAANGPRLAHPRTARPGPEAPPNGPPQSGRPSLGGTGDFYDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGMKVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDITNKDSFDNIQAWLTEIQEYAQQDVVLMLLGNKVDSTQERVVKREDGEKLAKEYGLPFMETSAKSGLNVDLAFTAIAKELKQRSTKAPSEPRFRLHDYVKREGRGVSCCRL", "length": 257 }, "evidence": [ { "id": "A0A8V0Z416", "url": "https://omabrowser.org/oma/group/A0A8V0Z416/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q29RR0-1", "protein_name": "Ras-related protein Rab-26", "gene_name": "RAB26", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRKKTPKSKAGSAPATSALPAANGPRPVRPGTARPGPEAPPNGPPQPGRSSVGGGGDFYDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVVDVDGMKVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKASFDSIQAWLTEIQEHAQDDVVLMLLGNKVDSAQERAVKREDAEKLAKDYGLPFMETSAKTGLNVDLAFTAIAKELKQRHTKAPSEPRFQLHDYIKREGRGASCCRP", "length": 256 }, "evidence": [ { "id": "A0A8V0Z416", "url": "https://omabrowser.org/oma/group/A0A8V0Z416/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q504M8-1", "protein_name": "Ras-related protein Rab-26", "gene_name": "Rab26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRKKTPKSKGGSEPATSTLPAAAAATNGPRLAHPRTVRPGPEAPPNGPPQSIRPSLGSTGDFYDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGMKVKLQIWDTAGQERFRSVTHAYYRDAHALLLLYDITNKDSFDNIQAWLTEIQEYAQQDVVLMLLGNKVDSTQDRVVKREDGEKLAKEYGLPFMETSARTGLNVDLAFTAIAKELKQRSAKAPSEPRFRLHDYVKREGRGVSCCRL", "length": 260 }, "evidence": [ { "id": "A0A8V0Z416", "url": "https://omabrowser.org/oma/group/A0A8V0Z416/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULW5-1", "protein_name": "Ras-related protein Rab-26", "gene_name": "RAB26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRKKTPKSKGASTPAASTLPTANGARPARSGTALSGPDAPPNGPLQPGRPSLGGGVDFYDVAFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGVKVKLQMWDTAGQERFRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQHDVALMLLGNKVDSAHERVVKREDGEKLAKEYGLPFMETSAKTGLNVDLAFTAIAKELKQRSMKAPSEPRFRLHDYVKREGRGASCCRP", "length": 256 }, "evidence": [ { "id": "A0A8V0Z416", "url": "https://omabrowser.org/oma/group/A0A8V0Z416/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "secretory granule membrane", "id": "GO:0030667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030667", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "trans-Golgi network transport vesicle", "id": "GO:0030140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030140", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "GMP binding", "id": "GO:0019002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019002", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "G protein activity", "id": "GO:0003925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003925", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulated exocytosis", "id": "GO:0045055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045055", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "exocrine system development", "id": "GO:0035272", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035272", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" }, { "name": "regulation protein catabolic process at presynapse", "id": "GO:0140251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140251", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z416", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z416" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8V0YVX9-1", "F1NSA8-1", "R4GJA4-1", "A0A1L1RKZ0-1", "E1BUS1-1", "Q5ZHW4-1", "Q90694-1", "P08070-1", "P09642-1", "P09643-1", "P09644-1", "P09645-1", "Q5F352-1", "Q5ZMS3-1", "Q90705-1", "Q90835-1", "Q90965-1", "Q98932-1", "A0A3Q2UHM4-1", "Q5ZHX1-1", "A0A1D5PT95-1", "E1BQI2-1", "F1NPF0-1", "A0A8V0XVU5-1", "A0A8V0XBX5-1", "A0A8V0Z564-1", "A0A8V0Y9R6-1", "A0A1D5PM27-1", "A0A8V0Z8U4-1", "A0A8V0ZJW2-1", "A0A8V1ABB1-1", "A0A8V0YDX6-1", "E1BWN3-1", "Q5F499-1", "Q5ZKU5-1", "P02552-1", "P08642-1", "P26990-1", "P42558-1", "Q5F470-1", "Q5ZIT5-1", "Q5ZJN2-1", "P50146-1", "A0A8V0ZNW3-1", "A0A8V0YIM0-1", "A0A8V0ZRZ2-1", "A0A8V1A9Z8-1", "Q1KME6-1", "Q5ZLG1-1", "P84172-1", "A0A8V1ACG4-1", "A0A8V0YTL7-1", "A0A3Q2UG55-1", "A0A8V1AIF5-1", "Q5ZHV1-1", "A0A8V0Z5P2-1", "A0A8V0Y4A4-1", "A0A8V0YA62-1", "A0A8V0YVM3-1", "A0A1D5P1F5-1", "A0A8V1ADZ7-1", "F1NWF1-1", "A0A8V1AP30-1", "A0A8V0XDD5-1", "A0A8V0XMC5-1", "A0A8V0YWW1-1", "A0A8V0ZR14-1", "A0A8V0Y2H3-1", "Q5ZJD3-1", "Q5ZM73-1", "Q5ZM83-1", "A0A8V0YTY9-1", "A0A8V0ZXW3-1", "A0A8V1AHB3-1", "A0A8V0YDI7-1", "A0A1D5NV13-1", "A0A8V0XGK7-1", "A0A8V0YHK2-1", "A0A8V0XC33-1", "A0A8V0XKC3-1", "F1P278-1", "A0A8V0ZG00-1", "A0A8V1AGP3-1", "A0A8V1AN75-1", "A0A8V0Z416-1", "A0A8V1A0V4-1", "A0A8V1A8Q7-1", "A0A8V1ABD3-1", "A0A8V1API8-1", "A0A8V0YIU8-1", "A0A8V0X962-1", "A0A8V1AKH3-1", "P79784-1", "A0A1D5P533-1", "A0A8V1A8I5-1", "A0A8V1AE09-1", "Q9PSX7-1", "Q5ZKR4-1", "A0A8V0YGN8-1", "A0A8V0XNL0-1", "A0A8V0Y3H2-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A1D5NV13", "gene_name": "RIT2", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5NV13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5NV13" } ] } ] }, { "uniprot_ac": "A0A1D5P1F5", "gene_name": "RAB40C", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P1F5" } ] } ] }, { "uniprot_ac": "A0A1D5P533", "gene_name": "RASEF", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5P533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5P533" } ] } ] }, { "uniprot_ac": "A0A1D5PM27", "gene_name": "OPA1", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A1D5PM27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PM27" } ] } ] }, { "uniprot_ac": "A0A1D5PT95", "gene_name": "KRAS", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1D5PT95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1D5PT95" } ] } ] }, { "uniprot_ac": "A0A1L1RKZ0", "gene_name": "RASL11AL", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A1L1RKZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A1L1RKZ0" } ] } ] }, { "uniprot_ac": "A0A3Q2UG55", "gene_name": "RAB9B", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3Q2UG55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UG55" } ] } ] }, { "uniprot_ac": "A0A3Q2UHM4", "gene_name": "DNM1L", "activity": [ { "ec_number": "3.6.5.5", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] }, { "ec_number": "3.6.5.5", "activity": "", "evidence": [ { "id": "A0A3Q2UHM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2UHM4" } ] } ] }, { "uniprot_ac": "A0A8V0X962", "gene_name": "RAB31", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8V0X962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0X962" } ] } ] }, { "uniprot_ac": "A0A8V0XBX5", "gene_name": 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CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052551.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015152079.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152079", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152079" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z419", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z419" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BPIL3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z419", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z419", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z419", "database": "AlphaFoldDB", "categories": [] }, { "id": "419290", "url": "https://www.ncbi.nlm.nih.gov/gene/419290", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001124", "database": 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"refseq": { "ac": "XP_040523564", "name": "NF-kappa-B inhibitor epsilon", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040523564" }, "gene_names": [ { "name": "NFKBIE", "type": "recommended", "evidence": [ { "id": "A0A8V0Z434", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z434" } ] }, { "name": "NFKBIE", "type": "synonym", "evidence": [ { "id": "XP_040523564", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040523564" } ] } ], "protein_names": [ { "name": "NF-kappa-B inhibitor epsilon", "type": "synonym", "evidence": [ { "id": "XP_040523564", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040523564" } ] }, { "name": "NFKB inhibitor epsilon", "type": "synonym", "evidence": [ { "id": "A0A8V0Z434", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z434/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052575.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040523564", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040523564" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z434", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z434" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NFKBIE", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z434", "locus": { "chromosome": "3", "start_pos": 29949580, "end_pos": 29941689, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019572", "url": "https://www.ensembl.org/id/ENSGALG00010019572" } ] } } ], "crossref": [ { "id": "A0A8V0Z434", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z434", "database": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR46680", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46680", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46680:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46680:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040523564", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040523564", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z434", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z434", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z434-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z434-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARPAGGECWEGEDGQCDSGIESLRSLPGGRDNPAPADTPTLTEPPTPAGETPTAAGESPAPCEPATPSEERLDSSYGSGALPEALPTAEPPPPPPPDGPNRRQLEALTYVSEDGDTLVHLAIIHCVPDVALCCIAQLPRELLEIQNDLFQTPLHLAVYLEQPSVVQALIHKGVNPGLQDRNGNTPLHLACEQQRLRCAQQLLQGTTEPPGHLQDLQLQNWQGLACLHISTLKGNIQMMSLLLQSGANIDVREGTSGKTPLHMAVECHNRSAVQFLLHNGAYVDAQMYNGCTPLHLAVGRKDAAIAAILSHSGADTLLRNMENETAQDLADGNDDLLALLPFDDLKISGKPVVCSE", "length": 356, "header": "tr|A0A8V0Z434-1|A0A8V0Z434_CHICK Isoform 1 of NFKB inhibitor epsilon OS=Gallus gallus OX=9031 GN=NFKBIE PE=1 SV=1 CANONICAL=A0A8V0Z434-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z434-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z434/entry#A0A8V0Z434-1", "sequence": { "sequence": 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"prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 67, "start_aa": "Thr", "end_pos": 67, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr67", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:421438", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:421438", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V1H6-1", "protein_name": "NF-kappa-B inhibitor epsilon", "gene_name": "NFKBIE", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSEARKGPDETDESQYDSGIESLRSLRSLPEPTPAPGSGPSDGGPQPWTHPPGTAEKSQEKEDTDGERADSTYGSSSLTEPLPLFGDPKTEDPVPDSPLPAARALSPQQLEALTYISEDGDTLVHLAVIHDSPAVLLCCLAMLPQEVLDIQNNLYQTALHLAVHLDQPGAVQALVLKGASRVLQDRHGDTALHVACQRQHLACARCLLEGRPEPGRGPPHSLDLQLQNWQGLACLHIATLQRNRPLMELLLQNGADIDAQEGTSGKTALHLAVETQERGLVQFLLQAGARVDARMLNGCTPLHLAAGRGLSSISSTLCQAGADSLLRNVEDETPQDLAEDPFALLPFDDLKISGKPLLCAD", "length": 361 }, "evidence": [ { "id": "A0A8V0Z434", "url": "https://omabrowser.org/oma/group/A0A8V0Z434/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HC82-1", "protein_name": "NF-kappa-B inhibitor epsilon", "gene_name": "Nfkbie", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDAQKGPDEADDSQCDSGIESLRSLRSLPEPTAAPVSEPSHRGCPQPWSHPPDTNKEPGEKEDADGERADSTYASSSLTESLPLLGRPEVEDPAPDSPLPHTEVLSPQQLEALTYISEDGDTLLHLAVIHEAPSVLLCCLAFLPQEVLDIQNNLYQTALHLAVHLDQPDIVRALVLKGASQVLQDQHGDTALHVACQRQNLACACCLLEEQPEPGREPSHPLDLQLKNWQGLACLHIATLQRNQPLIELLLQNGADINAQEATSGKTALHLAVETQEHSLVQFLLRAGAQVDARMLNGCTPLHLAAGRGLSSISSTLCEAGADSLLLNVEDETPQDLAEDLLSYLPFDDLKISGKPLLCTD", "length": 362 }, "evidence": [ { "id": "A0A8V0Z434", "url": "https://omabrowser.org/oma/group/A0A8V0Z434/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O54910-1", "protein_name": "NF-kappa-B inhibitor epsilon", "gene_name": "Nfkbie", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"MSDARKGPDEADDSQCDSGIESLRSLRSLPDPAAAPVSGSSHSGCPQPWSHAPKTDKEPEGKEDADGERADSTYASSSLTESLPLLERPEAKDPNPPTPSSPVSPAGVLSPQQLEALTYISEDGDTLLHLAVIHEAPSVLFCCLAFLPQEVLDIQNNLYQTALHLAVHLDQPDVVRALVLKGASRILQDQHGDTALHVACQRQNLACACCLLEEQPEPGRQPSHPLDLQLKNWQGLACLHIATLQRNQPLIELLLQNGADIDAQEGTSGKTALHLAVETQERSLVQFLLQAGARVDARMLNGCTPLHLAAGRGLNSISSTLCEAGADSLLLNVEDETPQDLAEDLLSYLPFDDLKISGKPLLCTD", "length": 365 }, "evidence": [ { "id": "A0A8V0Z434", "url": "https://omabrowser.org/oma/group/A0A8V0Z434/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z434", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z434" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z452" } ] } ], "protein_names": [ { "name": "Thioredoxin related transmembrane protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z452/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z452", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z452" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMX1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z452", "locus": { "chromosome": "5", "start_pos": 57791685, "end_pos": 57785127, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019594", "url": "https://www.ensembl.org/id/ENSGALG00010019594" } ] } } ], "crossref": [ { "id": "A0A8V0Z452", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z452", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR052454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z452", "url": "https://www.orthodb.org/?gene=A0A8V0Z452", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z9Z9", "url": "https://www.orthodb.org/?gene=A0A8V0Z9Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46107:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46107:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z452", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z452", "database": 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"A0A8V0Z452-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z452/entry#A0A8V0Z452-1", "sequence": { "sequence": "MGKCPFLSRCPSFSLCRTLIHTSLCLMTTSHDKDGVLRKYQGARMKTGFINFIKDQEWKSTEPVSSWFHPSFYLLSSMPALFQMSVWIRHCHGYLTESIGMQVWGSYAMFLLATLFSGLILQLIMVFLADCLCASKKHRPAQYPYSILCNFFALVENPAVYGCKSSLLQTASYPCPPTHDISNPTSRGGQHQHVYLGVGSLNEDRLSSAMKDPWQGERIITRYAQQPEPACNCWLFSAECLFCLCFLALSPVSSLTEYKNRAVLWLLLVRVQLAGKRQSYSLQFLLRRNKEYVLPGE", "length": 297, "header": "tr|A0A8V0Z452-1|A0A8V0Z452_CHICK Isoform 1 of Thioredoxin related transmembrane protein 1 OS=Gallus gallus OX=9031 GN=TMX1 PE=4 SV=1 CANONICAL=A0A8V0Z452-1" }, "locus": { "chromosome": "5", "start_pos": 57789478, "end_pos": 57785846, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047255.1", "url": "https://www.ensembl.org/id/ENSGALT00010047255.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028007.1", "url": "https://www.ensembl.org/id/ENSGALP00010028007.1" } ] } }, { "isoform_ac": "A0A8V0Z9Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z452/entry#A0A8V0Z9Z9-1", "sequence": { "sequence": "MGKCPFLSRCPSFSLCRTLIHTSLCLMTTSHDKDGVLRKYQGARMKTGFINFIKDQEWKSTEPVSSWFHPSFYLLSSMPALFQMSVWIRHCHGYLTESIGMQVWGSYAMFLLATLFSGLILQLIMVFLADCLCASKKHRPAQYPYSSRSEKNEPCRGLLAPGGKLFGLVLCWSSER", "length": 176, "header": "tr|A0A8V0Z9Z9-1|A0A8V0Z452_CHICK Computationally mapped isoform of Thioredoxin related transmembrane protein 1 OS=Gallus gallus OX=9031 GN=TMX1 PE=4 SV=1 CANONICAL=A0A8V0Z452-1" }, "locus": { "chromosome": "5", "start_pos": 57790681, "end_pos": 57785846, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047264.1", "url": "https://www.ensembl.org/id/ENSGALT00010047264.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028014.1", "url": "https://www.ensembl.org/id/ENSGALP00010028014.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4Q5-1", "uniprot_ac": "A0A8V0Z4Q5", "uniprot_id": "A0A8V0Z4Q5_CHICK", "mass": { "chemical_mass": 20561.0, "monoisotopic_mass": 20561.0 }, "refseq": { "ac": "XP_040503349", "name": "LYR motif-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503349" }, "gene_names": [ { "name": "LYRM1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q5" } ] }, { "name": "LYRM1", "type": "synonym", "evidence": [ { "id": "XP_040503349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503349" } ] } ], "protein_names": [ { "name": "LYR motif containing 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q5/entry#names_and_taxonomy" } ] }, { "name": "LYR motif-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040503349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503349" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040503349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503349" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LYRM1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q5", "locus": { "chromosome": "14", "start_pos": 15064232, "end_pos": 15052014, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018014", "url": "https://www.ensembl.org/id/ENSGALG00010018014" } ] } } ], "crossref": [ { "id": "A0A8V0Z4Q5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4Q5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20261", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20261", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427003", "url": "https://www.ncbi.nlm.nih.gov/gene/427003", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z463", "url": "https://www.orthodb.org/?gene=A0A8V0Z463", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4Q5", "url": "https://www.orthodb.org/?gene=A0A8V0Z4Q5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14273", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14273", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14273:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14273:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_040503349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040503349", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z463", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z463", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z463-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z463-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLCWTGSSGFNSELLFTAISILSLGGGNTLTPIELCGKTVHVVVFHTHWGFCGVGLFQMTAVMRQEVLGLYRKIFRIAKKWQSASGQAEETTAEREYIIKEAKTLFRKNKDVMDPKLIKQCIDECEARIQIGLHYNIPYPRPIHLPPMGLTQKQGRTFRHQEKLRKISKPIYLKSHDEIS", "length": 180, "header": "tr|A0A8V0Z4Q5-1|A0A8V0Z4Q5_CHICK Isoform 1 of LYR motif containing 1 OS=Gallus gallus OX=9031 GN=LYRM1 PE=3 SV=1 CANONICAL=A0A8V0Z4Q5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z463-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q5/entry#A0A8V0Z463-1", "sequence": { "sequence": "MWGHVLGIRFCSSCGSVHHVLCTKVVEGLLFPEDSSDPAPNCSGLMSGYIQQLELQMTAVMRQEVLGLYRKIFRIAKKWQSASGQAEETTAEREYIIKEAKTLFRKNKDVMDPKLIKQCIDECEARIQIGLHYNIPYPRPIHLPPMGLTQKQGRTFRHQEKLRKISKPIYLKSHDEIS", "length": 178, "header": "tr|A0A8V0Z463-1|A0A8V0Z4Q5_CHICK Computationally mapped isoform of LYR motif containing 1 OS=Gallus gallus OX=9031 GN=LYRM1 PE=3 SV=1 CANONICAL=A0A8V0Z4Q5-1" }, "locus": { "chromosome": "14", "start_pos": 15062142, "end_pos": 15057150, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043531.1", "url": "https://www.ensembl.org/id/ENSGALT00010043531.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025887.1", "url": "https://www.ensembl.org/id/ENSGALP00010025887.1" } ] } }, { "isoform_ac": "A0A8V0Z4Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q5/entry#A0A8V0Z4Q5-1", "sequence": { "sequence": "MLCWTGSSGFNSELLFTAISILSLGGGNTLTPIELCGKTVHVVVFHTHWGFCGVGLFQMTAVMRQEVLGLYRKIFRIAKKWQSASGQAEETTAEREYIIKEAKTLFRKNKDVMDPKLIKQCIDECEARIQIGLHYNIPYPRPIHLPPMGLTQKQGRTFRHQEKLRKISKPIYLKSHDEIS", "length": 180, "header": "tr|A0A8V0Z4Q5-1|A0A8V0Z4Q5_CHICK Isoform 1 of LYR motif containing 1 OS=Gallus gallus OX=9031 GN=LYRM1 PE=3 SV=1 CANONICAL=A0A8V0Z4Q5-1" }, "locus": { "chromosome": "14", "start_pos": 15062142, "end_pos": 15058118, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043539.1", "url": "https://www.ensembl.org/id/ENSGALT00010043539.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025894.1", "url": "https://www.ensembl.org/id/ENSGALP00010025894.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Q5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Q5" }, { "id": "PF05347", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05347" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Complex 1 LYR protein", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 128, "start_aa": "Gln", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z466-1", "uniprot_ac": "A0A8V0Z466", "uniprot_id": "A0A8V0Z466_CHICK", "mass": { "chemical_mass": 143690.0, "monoisotopic_mass": 143690.0 }, "refseq": { "ac": "XP_025008100", "name": "mitogen-activated protein kinase kinase kinase 19 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008100" }, "gene_names": [ { "name": "MAP3K19", "type": "recommended", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ] }, { "name": "MAP3K19", "type": "synonym", "evidence": [ { "id": "XP_025008100", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008100" } ] } ], "protein_names": [ { "name": "Mitogen-activated protein kinase kinase kinase 19", "type": "recommended", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466/entry#names_and_taxonomy" } ] }, { "name": "SPS1/STE20-related protein kinase YSK4", "type": "synonym", "evidence": [ { "id": "A0A8V0Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466/entry#names_and_taxonomy" } ] }, { "name": "mitogen-activated protein kinase kinase kinase 19 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025008100", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008100" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025008100.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025008100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008100" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MAP3K19", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466", "locus": { "chromosome": "7", "start_pos": 30099427, "end_pos": 30120332, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019600", "url": "https://www.ensembl.org/id/ENSGALG00010019600" } ] } } ], "crossref": [ { "id": "cd06631", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06631", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "429048", "url": "https://www.ncbi.nlm.nih.gov/gene/429048", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RNMCSFQ", "url": "https://omabrowser.org/oma/group/RNMCSFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z466", "url": "https://www.orthodb.org/?gene=A0A8V0Z466", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11584", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11584", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11584:SF369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11584:SF369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025008100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025008100", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z466-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADAVRNPAGEGRFQDLKTSKDSMSEKQKIKGRSTEGHGAVVALPNADKIVEEICDSYKALGINSQKTQTTRLWQDKQVACCQSKKQLTLQMGQHTSLPFLLKKGIIRHGFDFSFLLQASCPESNTPKSCQDLGAVRIIKAHMQQRFDITILENRNKRSEFHLPPVTFRPIRTIHLALLDNIFVNKHTKIRNIWNIMKSISQPIKSATKFYQYQLGNIVKRQAEKSSGVIVATTSEKLTPTEGLYCFSKNKYCKFPNNKKEEIENNLKWTEAGVAANTEKNNQKSQFSVACENVDIMTQDSFCDASLFYLSSSNAVKNCGIFTALCPVSKSTDILRAGKKEEREENSYRTGIEENITDTVLHCRPCEDAECVLFMLGDRNLDSSCKNEVIESCHVLEDNSVAAVIPGEEMRDDCSGKQIENNVCLLKFEMENKAMSEVTAKGQSELVPVAHVTFSEQELPRKPHAAKHPSRKRSTIRSLPPHITQSFNILARKDNDKSEIKMNRNKCSSKSKMSSKTRTLEGLVVSDEISVKRNTQKMNAKSKIFPSLQLPCMESETFLKCQKKIPQANKYHFLQSSQKLKKQSCSCSCKNLVISKKPVTPLSLQYAQSASDFVQLKYSDMFKKINSNDKGPDVYEMFGTPVYSHVRELDQLENSSYRNACSAPPGRCTASTCRSTCNKRRDSSQIRNTQKRTHCKPKKTVSVTKQKQKGLRANNKSIELSGSNTKQDNVISSGPDCQIQTPSSMTLFHGDTDHQLIVLEELSRSTKPNKILSNSKLSTIKEASLEQSLGSQDLSNHQIAASCSLDLLQLNDKDYTECAAPSNITADQNICVPQYIVDMNGCKSLESDQASFKTINQREALPFSDSQECQFLRNKLSHSWSYTPQNSILANELTQPSMIQTTNVTSPSFQTSQNILSWAGNKDVTDELLCCLAAEFLMLGDKDINSSRTKHAGSKMQNTCTKEEGNIMNRDGEIVDNDLEKSHRKAFLASSEESGLLNFEESTQVPGSNLNNKDTIMWTRGEVLGKGAYGTVYCGLTNQGQLIAVKQVVLDTSDQLTTEKEYQKLHEEVDLLKTLKHVNIVTYLGTCLEDNILSIFMEFVPGGSISSILNRFGPLPEIVLCKYTKQILEGVAYLHDNCVVHRDIKGNNVMLMPNGIVKLIDFGCARRLAWVSLSGTHSEMLKSVHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRIAAMFYIGAHRGLMPSLPDRFSGTAVDFVHACLTRDQHERPSALQLLDHPFVKGRQ", "length": 1286, "header": "tr|A0A8V0Z466-1|A0A8V0Z466_CHICK Isoform 1 of Mitogen-activated protein kinase kinase kinase 19 OS=Gallus gallus OX=9031 GN=MAP3K19 PE=3 SV=1 CANONICAL=A0A8V0Z466-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z466-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466/entry#A0A8V0Z466-1", "sequence": { "sequence": "MAADAVRNPAGEGRFQDLKTSKDSMSEKQKIKGRSTEGHGAVVALPNADKIVEEICDSYKALGINSQKTQTTRLWQDKQVACCQSKKQLTLQMGQHTSLPFLLKKGIIRHGFDFSFLLQASCPESNTPKSCQDLGAVRIIKAHMQQRFDITILENRNKRSEFHLPPVTFRPIRTIHLALLDNIFVNKHTKIRNIWNIMKSISQPIKSATKFYQYQLGNIVKRQAEKSSGVIVATTSEKLTPTEGLYCFSKNKYCKFPNNKKEEIENNLKWTEAGVAANTEKNNQKSQFSVACENVDIMTQDSFCDASLFYLSSSNAVKNCGIFTALCPVSKSTDILRAGKKEEREENSYRTGIEENITDTVLHCRPCEDAECVLFMLGDRNLDSSCKNEVIESCHVLEDNSVAAVIPGEEMRDDCSGKQIENNVCLLKFEMENKAMSEVTAKGQSELVPVAHVTFSEQELPRKPHAAKHPSRKRSTIRSLPPHITQSFNILARKDNDKSEIKMNRNKCSSKSKMSSKTRTLEGLVVSDEISVKRNTQKMNAKSKIFPSLQLPCMESETFLKCQKKIPQANKYHFLQSSQKLKKQSCSCSCKNLVISKKPVTPLSLQYAQSASDFVQLKYSDMFKKINSNDKGPDVYEMFGTPVYSHVRELDQLENSSYRNACSAPPGRCTASTCRSTCNKRRDSSQIRNTQKRTHCKPKKTVSVTKQKQKGLRANNKSIELSGSNTKQDNVISSGPDCQIQTPSSMTLFHGDTDHQLIVLEELSRSTKPNKILSNSKLSTIKEASLEQSLGSQDLSNHQIAASCSLDLLQLNDKDYTECAAPSNITADQNICVPQYIVDMNGCKSLESDQASFKTINQREALPFSDSQECQFLRNKLSHSWSYTPQNSILANELTQPSMIQTTNVTSPSFQTSQNILSWAGNKDVTDELLCCLAAEFLMLGDKDINSSRTKHAGSKMQNTCTKEEGNIMNRDGEIVDNDLEKSHRKAFLASSEESGLLNFEESTQVPGSNLNNKDTIMWTRGEVLGKGAYGTVYCGLTNQGQLIAVKQVVLDTSDQLTTEKEYQKLHEEVDLLKTLKHVNIVTYLGTCLEDNILSIFMEFVPGGSISSILNRFGPLPEIVLCKYTKQILEGVAYLHDNCVVHRDIKGNNVMLMPNGIVKLIDFGCARRLAWVSLSGTHSEMLKSVHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRIAAMFYIGAHRGLMPSLPDRFSGTAVDFVHACLTRDQHERPSALQLLDHPFVKGRQ", "length": 1286, "header": "tr|A0A8V0Z466-1|A0A8V0Z466_CHICK Isoform 1 of Mitogen-activated protein kinase kinase kinase 19 OS=Gallus gallus OX=9031 GN=MAP3K19 PE=3 SV=1 CANONICAL=A0A8V0Z466-1" }, "locus": { "chromosome": "7", "start_pos": 30120133, "end_pos": 30106876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047277.1", "url": "https://www.ensembl.org/id/ENSGALT00010047277.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028022.1", "url": "https://www.ensembl.org/id/ENSGALP00010028022.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "E9Q3S4-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 19", "gene_name": "Map3k19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSMPRPERHAESLLDICHEAGSTPMEMTVSQTENLTLQSISSSEDFDLEDDFSPFILAREGAAPRGENWPRRTEGVEIIVTFPPDPLQEASQEDLKESNQVTSEHQEREQVHPVSPPDDAEMVGLTGRMLTTQPSLLKTDGSSEELCGVDVALSPPRPCLDSSLAASAAGEVAPCVLKEQQRQSDEFPTSDISYSSRRTGLPLPPLSCLPMRSCIFNMEKSPKSPRHRERKVPSLSLSVPKLLEPLSRPLSQSAEFSSSKNHQEVTQEGPVEHTLRGSNCTLWSRNMCSFRKSGKQGVAESWPSQEMEGWDKTKTSGFKEGPSLFSCESVKEDTTPTERERDSGYHVSEMQRGGEDSQYLSSRKKESWTARVVERDSGVEHPILCKLLEVSNSEMTPAEEKEIGNENVPDAKSNSVHKSGAMEPHAASEEVSVPKNGPSVNSDGPAEELEGHRDIEQNRKIPMEEETNPEMNGVVPLTHIAFPGEGTSKGPARAEPHLQRRKRPAQNSNSFNLLAHREHDKLQTNTHRTKLDSRTKARNRAPPNLMVSIQASIKPNMHKNSIKTQVFPALELIDHRPHPSSKFQRRAPLTEKKSTHQTQKPKKQAFPRIGKHAGIKKPGIPLSAETTDPRLHFLDLKYSDMFKEINSASNGPGIYEMFGTPVYCHIREAERHDHRCYREIRTAPSGRCVVNKCQSSESDRCSNSRARLLQKRQHIKPPKPLHGLRQKHRGFISKDKGCKDMGGHTEDSVSEPDGQMKSPGNDFLSSKDDAQLMHLIPIPELSPEQKAPAPVSDLSIVEEIFTEECADEEGILNDDSLTQSLGDLKEPEGLHPQAPLVPSENSWAVLSEKRSGKRVSPEKHNVEPLDKINAEQMFPGYLEFDSLSEKSKTLVSFSSCSFQENLERAPSPTEQHWARSLEQDSLENNSTTYQTFGKISQEILDPGKNEELTDELLGCLVEELLALDEKDNNSCQIMTNEADAKNLNLVFSRRGNTIEELGRETTDVKLQRCINGFRIYDEENFLTSNEKKTLSDKSLNHEEAIFWTKGEILGRGAYGTVYCGLTSLGQLIAVKQVALDTSDKLATEKEYRKLQEEVDLLKALKHVNIVAYLGTCLEENTLSIFMEFVPGGSISSIINRFGPLPEMVFCKYTRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKSMRGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPARFSEPAADFVRLCLTRDQHERPSALQLLKHSFLKRSQ", "length": 1311 }, "evidence": [ { "id": "A0A8V0Z466", "url": "https://omabrowser.org/oma/group/A0A8V0Z466/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LVM0-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 19", "gene_name": "Map3k19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNKNKLIHDFLEVVSRGDVECICSHIPEVHSVLGNLDFQHPQTGNTPLITAAEENLSEVVEILLERGADITLCNYSNQTALHVANGDIQRQLLAGRGIQAPQMQLLRSSWQGDLERLRHLLACEEFLDINFPNSHGLTPLMLAVRDVDLFESLDVSTVYRPAEVLAELLRHHADPKLCDFSGKSAMHYVSQINSWRKQQLLVILTDSMPKPERHAESLLDICHEAGSTPMDMTVSKTENITLQSISSSSSEDFALDDDFSPSILAGEGTAPRGEGWPRRTEGVEILVTMFPPDSPQEASQEDLTESSQWGPGHPVSPAKEVEMVGLTSRMLTTQPSLLKTEGGSQELCGADVALSPPRPCLDPSTAIAAVREEAPHVLKVQPRKSDKFPTSDMRYSSRRTELPLPPPSLLPMRSSVFNMEKSPKFPRHGERKVPSLSLSVPKLLEPLSQPLSQSAEFSSAKNQQEVTWEGPPEHTLRGSDWAIWSRNLCSFRKSRKQRGVAESWRSQETKGGDKTETSGFEEGPFLFSCGSVKEDTAPIERERDSGCHISEISGREDSQYLLSGEKESWTDRAVEKDLEVEHPFLSELLEASNTKITLAEEKEIGNEKVPDSESNSVHRAGTVQPHAVLEELSVPKNIPRMNSDGPITGLLEGHGDTEENRKLPIEEETNPEMNGAVPLVHITFPGEGTPKGPARAKPNLQRRKHPVQSSGSPNILARQEHGKLQTNTHRTKARNRPPPNLMVSIQASIKPNVRKNSIKTQVFPALEFMDHRPHPPSKFQRRAPVTEKKSMCQTQKPKKQAFPHICKNAGIKKPGVVLSVETTDPRLHFLDLKYSDMFKEINSASNGPGIYEMFGTPVYSHIREAERHEHRHYHEICAAPSGRSVGNKCQPSQSDRCANSRARLLQKRPHVKPPKPSLGLKQKHRGLISKDKGCKGMGGHVEDSVSEPGWQTRPSANDSLSSKDEAQLTHLTLIPETSPEQRETPPLSDLSIVEEIFTEECADEEGILHNDSLTQSLGDLKALEGLHPQTPLVPSEDSWAVLSEKHSGKHVSPGKHDVGPLDKINADQMFTGYLEFDSLSDKSKTRVSFSRYSFQEKPESAPSPTEQPWAHSLDQDSLEDDSTTYQRFGKVSQGILDPGKNEELTDELLGCLVEELLAIDEKDNNSCRIMTNEADTRDLNLVFGRRGNTIEGLDRETTDVKLQRCINGFQIYDEENFLTSYEERTLSDNSLKHEEAIFWTKGEILGRGAYGTVYCGLTSLGQLIAVKQVALDSTDKLATEKEYRKLQEEVDLLKALKHVNIVAYLGTCLEENTLSIFMEFVPGGSISSIINRFGPLPETVFCKYTRQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKSMRGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDRFSEPAADFVRLCLTRDQHERPSALQLLTHAFMLRSQ", "length": 1506 }, "evidence": [ { "id": "A0A8V0Z466", "url": "https://omabrowser.org/oma/group/A0A8V0Z466/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "JNK cascade", "id": "GO:0007254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007254", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ], "pmid": "" }, { "name": "p38MAPK cascade", "id": "GO:0038066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z466" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1198, "end_pos": 1200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 655, "end_pos": 657, "annotation": "n_glycosylation_sequon" }, { "start_pos": 716, "end_pos": 718, "annotation": "n_glycosylation_sequon" }, { "start_pos": 824, "end_pos": 826, "annotation": "n_glycosylation_sequon" }, { "start_pos": 904, "end_pos": 906, "annotation": "n_glycosylation_sequon" }, { "start_pos": 946, "end_pos": 948, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6U1I9-1", "A0A8V0XNJ2-1", "A0A8V0ZUL0-1", "A0A8V0ZT63-1", "A0A8V1ACW2-1", "A0A8V0Z1X0-1", "A0A8V0YHN2-1", "A0A8V0YMN5-1", "A0A8V0Z807-1", "A0A8V0Z930-1", "A0A8V0YFR6-1", "A0A1D5P0M9-1", "A0A8V0ZBN6-1", "A0A3Q2U9U9-1", "A0A8V0YXZ5-1", "A0A8V0ZSP4-1", "A0A8V0ZXQ9-1", "A0A8V0ZZV3-1", "A0A8V1ADF0-1", "A0A8V0ZFT3-1", "A0A8V0ZA45-1", "A0A8V0ZB33-1", "A0A8V0ZD70-1", "A0A8V0Z8T4-1", "R4GIN8-1", "A0A8V0ZK64-1", "A0A8V0ZC16-1", "A0A8V0ZWW1-1", "E1BY69-1", "A0A8V0ZDW9-1", "A0A8V0ZKA2-1", "A0A3Q3B2F1-1", "F1P356-1", "A0A8V1AHA8-1", "Q8QFP8-1", "F1P011-1", 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XMX8" } ] } ] }, { "uniprot_ac": "A0A8V0XND6", "gene_name": "RIOK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XND6" } ] } ] }, { "uniprot_ac": "A0A8V0XNJ2", "gene_name": "CDK8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0XNJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNJ2" } ] } ] }, { "uniprot_ac": "A0A8V0XNK8", "gene_name": "PRKCQ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XNK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XNK8" } ] } ] }, { "uniprot_ac": "A0A8V0XQ14", "gene_name": "PLK4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8V0XQ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ14" } ] } ] }, { "uniprot_ac": "A0A8V0XQ97", "gene_name": "CDK14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XQ97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQ97" } ] } ] }, { "uniprot_ac": "A0A8V0XQQ4", "gene_name": "NME7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQQ4" } ] } ] }, { "uniprot_ac": "A0A8V0XQS0", "gene_name": "STK24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XQS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XQS0" } ] } ] }, { "uniprot_ac": "A0A8V0XS42", "gene_name": "MAP3K4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0XS42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XS42" } ] } ] }, { "uniprot_ac": "A0A8V0XU71", "gene_name": "MYO3A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XU71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU71" } ] } ] }, { "uniprot_ac": "A0A8V0XU96", "gene_name": "PRKD1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0XU96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XU96" } ] } ] }, { "uniprot_ac": "A0A8V0XUM6", "gene_name": "LATS1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XUM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XUM6" } ] } ] }, { "uniprot_ac": "A0A8V0XW11", "gene_name": "RPS6KA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0XW11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW11" } ] } ] }, { "uniprot_ac": "A0A8V0XW29", "gene_name": "CDKL2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0XW29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XW29" } ] } ] }, { "uniprot_ac": "A0A8V0XXB8", "gene_name": "MAPK15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0XXB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0XXB8" } ] } ] }, { "uniprot_ac": "A0A8V0Y074", "gene_name": "NEK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y074", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y074" } ] } ] }, { "uniprot_ac": "A0A8V0Y241", "gene_name": "LOC426385", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y241", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y241" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V0Y2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y2I5" } ] } ] }, { "uniprot_ac": "A0A8V0Y3D1", "gene_name": "LRRK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3D1" } ] } ] }, { "uniprot_ac": "A0A8V0Y3L2", "gene_name": "MLK4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0Y3L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y3L2" } ] } ] }, { "uniprot_ac": "A0A8V0Y457", "gene_name": "PRPF4B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y457" } ] } ] }, { "uniprot_ac": "A0A8V0Y4L8", "gene_name": "HUNK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0Y8X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y8X9" } ] } ] }, { "uniprot_ac": "A0A8V0Y935", "gene_name": "MAST4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0Y935", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y935" } ] } ] }, { "uniprot_ac": "A0A8V0Y955", "gene_name": "PAK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0Y955", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Y955" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFH4" } ] } ] }, { "uniprot_ac": "A0A8V0YFL1", "gene_name": "CDK19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0YFL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFL1" } ] } ] }, { "uniprot_ac": "A0A8V0YFP8", "gene_name": "RIPK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFP8" } ] } ] }, { "uniprot_ac": "A0A8V0YFR6", "gene_name": "TNIK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YFR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YFR6" } ] } ] }, { "uniprot_ac": "A0A8V0YGW2", "gene_name": "STK32B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YGW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YGW2" } ] } ] }, { "uniprot_ac": "A0A8V0YHH2", "gene_name": "STK38L", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHH2" } ] } ] }, { "uniprot_ac": "A0A8V0YHN2", "gene_name": "RPS6KA1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YHN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YHN2" } ] } ] }, { "uniprot_ac": "A0A8V0YIV6", "gene_name": "DYRK1A", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V0YIV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YIV6" } ] } ] }, { "uniprot_ac": "A0A8V0YJP9", "gene_name": "RIOK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YJP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YJP9" } ] } ] }, { "uniprot_ac": "A0A8V0YK18", "gene_name": "CDC42BPB", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YK18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YK18" } ] } ] }, { "uniprot_ac": "A0A8V0YKK3", "gene_name": "MAP4K4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YKK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YKK3" } ] } ] }, { "uniprot_ac": "A0A8V0YLV1", "gene_name": "MARK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YLV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YLV1" } ] } ] }, { "uniprot_ac": "A0A8V0YM22", "gene_name": "MYO3AL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM22" } ] } ] }, { "uniprot_ac": "A0A8V0YM96", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YM96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YM96" } ] } ] }, { "uniprot_ac": "A0A8V0YMB3", "gene_name": "STK32A", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMB3" } ] } ] }, { "uniprot_ac": "A0A8V0YMN5", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YMN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YMN5" } ] } ] }, { "uniprot_ac": "A0A8V0YNI5", "gene_name": "NIM1K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YNI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YNI5" } ] } ] }, { "uniprot_ac": "A0A8V0YRC9", "gene_name": "TNK2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YRC9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8V0YRC9", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YSH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YSH3" } ] } ] }, { "uniprot_ac": "A0A8V0YTI1", "gene_name": "TSSK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTI1" } ] } ] }, { "uniprot_ac": "A0A8V0YTL9", "gene_name": "VRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTL9" } ] } ] }, { "uniprot_ac": "A0A8V0YTN5", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTN5" } ] } ] }, { "uniprot_ac": "A0A8V0YTP2", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0YTP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0YTP2", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8V0ZB38", "gene_name": "CIITA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZB38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZB38" } ] } ] }, { "uniprot_ac": "A0A8V0ZBN6", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V0ZBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBN6" } ] } ] }, { "uniprot_ac": "A0A8V0ZBZ2", "gene_name": "MAP3K9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZBZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBZ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZC16", "gene_name": "KALRN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZC16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC16" } ] } ] }, { "uniprot_ac": "A0A8V0ZD40", "gene_name": "CDC2L1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V0ZD40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD40" } ] } ] }, { "uniprot_ac": "A0A8V0ZD48", "gene_name": "PRKCE", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZD48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD48" } ] } ] }, { "uniprot_ac": "A0A8V0ZD60", "gene_name": "STK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD60" } ] } ] }, { "uniprot_ac": "A0A8V0ZD70", "gene_name": "DCLK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZD70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZD70" } ] } ] }, { "uniprot_ac": "A0A8V0ZDW9", "gene_name": "NEK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZDW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZDW9" } ] } ] }, { "uniprot_ac": "A0A8V0ZFM2", "gene_name": "LMTK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFM2" } ] } ] }, { "uniprot_ac": "A0A8V0ZFP1", "gene_name": "TTBK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFP1" } ] } ] }, { "uniprot_ac": "A0A8V0ZFT3", "gene_name": "LRRK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZFT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZFT3" } ] } ] }, { "uniprot_ac": "A0A8V0ZGY3", "gene_name": "HIPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZGY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZGY3" } ] } ] }, { "uniprot_ac": "A0A8V0ZH91", "gene_name": "WNK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZH91" } ] } ] }, { "uniprot_ac": "A0A8V0ZI32", "gene_name": "STK16", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZI32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI32" } ] } ] }, { "uniprot_ac": "A0A8V0ZK64", "gene_name": "PDPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZK64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZK64" } ] } ] }, { "uniprot_ac": "A0A8V0ZKA2", "gene_name": "EIF2AK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKA2" } ] } ] }, { "uniprot_ac": "A0A8V0ZKM9", "gene_name": "STK36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZKM9" } ] } ] }, { "uniprot_ac": "A0A8V0ZLU3", "gene_name": "TLK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZLU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZLU3" } ] } ] }, { "uniprot_ac": "A0A8V0ZMK1", "gene_name": "PIKFYVE", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZMK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZMK1" } ] } ] }, { "uniprot_ac": "A0A8V0ZNP7", "gene_name": "SGK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZNP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZNP7" } ] } ] }, { "uniprot_ac": "A0A8V0ZPX2", "gene_name": "ALPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZPX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZPX2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQJ2", "gene_name": "RPS6KB2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQJ2" } ] } ] }, { "uniprot_ac": "A0A8V0ZQT5", "gene_name": "SLC13A3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZQT5" } ] } ] }, { "uniprot_ac": "A0A8V0ZRX1", "gene_name": "SETD6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] }, { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A8V0ZRX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZRX1" } ] } ] }, { "uniprot_ac": "A0A8V0ZSB4", "gene_name": "SIK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSB4" } ] } ] }, { "uniprot_ac": "A0A8V0ZSP4", "gene_name": "PKN2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZSP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZSP4" } ] } ] }, { "uniprot_ac": "A0A8V0ZT63", "gene_name": "STK25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZT63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZT63" } ] } ] }, { "uniprot_ac": "A0A8V0ZUC6", "gene_name": "PAK6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUC6" } ] } ] }, { "uniprot_ac": "A0A8V0ZUL0", "gene_name": "PASK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUL0" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU8", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU8" } ] } ] }, { "uniprot_ac": "A0A8V0ZUU9", "gene_name": "MKNK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZUU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZUU9" } ] } ] }, { "uniprot_ac": "A0A8V0ZWC7", "gene_name": "EIF2AK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZWC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWC7" } ] } ] }, { "uniprot_ac": "A0A8V0ZWW1", "gene_name": "MAP3K12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V0ZWW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZWW1" } ] } ] }, { "uniprot_ac": "A0A8V0ZXQ9", "gene_name": "PRKG1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8V0ZXQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZXQ9" } ] } ] }, { "uniprot_ac": "A0A8V0ZYU6", "gene_name": "TNNI3K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZYU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZYU6" } ] } ] }, { "uniprot_ac": "A0A8V0ZZE4", "gene_name": "OBSCN", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZE4" } ] } ] }, { "uniprot_ac": "A0A8V0ZZK5", "gene_name": "STK38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZK5" } ] } ] }, { "uniprot_ac": "A0A8V0ZZV3", "gene_name": "MYO3B", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V0ZZV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZZV3" } ] } ] }, { "uniprot_ac": "A0A8V1A069", "gene_name": "TESK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A069", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A069" } ] } ] }, { "uniprot_ac": "A0A8V1A0W4", "gene_name": "ULK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0W4" } ] } ] }, { "uniprot_ac": "A0A8V1A0Y8", "gene_name": "MAST2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A0Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A0Y8" } ] } ] }, { "uniprot_ac": "A0A8V1A1P3", "gene_name": "SRPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A1P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1P3" } ] } ] }, { "uniprot_ac": "A0A8V1A1Y7", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1A1Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A1Y7" } ] } ] }, { "uniprot_ac": "A0A8V1A2T9", "gene_name": "MAP3K14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8V1A2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A2T9" } ] } ] }, { "uniprot_ac": "A0A8V1A3T8", "gene_name": "MAST3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A3T8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A3T8" } ] } ] }, { "uniprot_ac": "A0A8V1A4A1", "gene_name": "CAMKK2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1A4A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4A1" } ] } ] }, { "uniprot_ac": "A0A8V1A4J8", "gene_name": "MAPKAPK5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4J8" } ] } ] }, { "uniprot_ac": "A0A8V1A4Q4", "gene_name": "MAPK3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1A4Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4Q4" } ] } ] }, { "uniprot_ac": "A0A8V1A4V7", "gene_name": "HIPK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A4V7" } ] } ] }, { "uniprot_ac": "A0A8V1A513", "gene_name": "DAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A513" } ] } ] }, { "uniprot_ac": "A0A8V1A675", "gene_name": "CSNK1G2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A675", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A675" } ] } ] }, { "uniprot_ac": "A0A8V1A7E0", "gene_name": "DYRK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E0" } ] } ] }, { "uniprot_ac": "A0A8V1A7E9", "gene_name": "SIK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7E9" } ] } ] }, { "uniprot_ac": "A0A8V1A7M0", "gene_name": "STK39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7M0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7M0" } ] } ] }, { "uniprot_ac": "A0A8V1A7P9", "gene_name": "DCAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A7P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A7P9" } ] } ] }, { "uniprot_ac": "A0A8V1A9S5", "gene_name": "NUAK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1A9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1A9S5" } ] } ] }, { "uniprot_ac": "A0A8V1ABF3", "gene_name": "PRKAA2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ABF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABF3" } ] } ] }, { "uniprot_ac": "A0A8V1ABP4", "gene_name": "DSTYK", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8V1ABP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABP4" } ] } ] }, { "uniprot_ac": "A0A8V1ABR8", "gene_name": "CAMK4L", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1ABR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ABR8" } ] } ] }, { "uniprot_ac": "A0A8V1AC40", "gene_name": "CDK18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8V1AC40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AC40" } ] } ] }, { "uniprot_ac": "A0A8V1ACB5", "gene_name": "MAPK13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ACB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACB5" } ] } ] }, { "uniprot_ac": "A0A8V1ACF6", "gene_name": "PIM1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACF6" } ] } ] }, { "uniprot_ac": "A0A8V1ACK0", "gene_name": "MAPKAPK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACK0" } ] } ] }, { "uniprot_ac": "A0A8V1ACW2", "gene_name": "WNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ACW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ACW2" } ] } ] }, { "uniprot_ac": "A0A8V1ADF0", "gene_name": "MAP2K2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1ADF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADF0" } ] } ] }, { "uniprot_ac": "A0A8V1ADN9", "gene_name": "NLK", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8V1ADN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADN9" } ] } ] }, { "uniprot_ac": "A0A8V1ADT4", "gene_name": "MKNK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1ADT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1ADT4" } ] } ] }, { "uniprot_ac": "A0A8V1AE45", "gene_name": "ERN1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AE45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AE45" } ] } ] }, { "uniprot_ac": "A0A8V1AEH4", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AEH4" } ] } ] }, { "uniprot_ac": "A0A8V1AFS4", "gene_name": "STKLD1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AFS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AFS4" } ] } ] }, { "uniprot_ac": "A0A8V1AG70", "gene_name": "LOC100857512", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AG70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AG70" } ] } ] }, { "uniprot_ac": "A0A8V1AH12", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AH12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AH12" } ] } ] }, { "uniprot_ac": "A0A8V1AHA8", "gene_name": "NEK4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AHA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AHA8" } ] } ] }, { "uniprot_ac": "A0A8V1AIY7", "gene_name": "AATK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AIY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AIY7" } ] } ] }, { "uniprot_ac": "A0A8V1AJA4", "gene_name": "RPS6KB1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AJA4" } ] } ] }, { "uniprot_ac": "A0A8V1AKW4", "gene_name": "MAP2K4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8V1AKW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AKW4" } ] } ] }, { "uniprot_ac": "A0A8V1AM12", "gene_name": "GSG2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AM12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AM12" } ] } ] }, { "uniprot_ac": "A0A8V1AMK5", "gene_name": "PRKCA", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8V1AMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMK5" } ] } ] }, { "uniprot_ac": "A0A8V1AMQ2", "gene_name": "CAMKK1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8V1AMQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AMQ2" } ] } ] }, { "uniprot_ac": "A0A8V1AP60", "gene_name": "KSR1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8V1AP60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V1AP60" } ] } ] }, { "uniprot_ac": "E1BQN6", "gene_name": "PRKCZ", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BQN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQN6" } ] } ] }, { "uniprot_ac": "E1BQV7", "gene_name": "SLK", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BQV7" } ] } ] }, { "uniprot_ac": "E1BUG0", "gene_name": "CDK12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E1BUG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BUG0" } ] } ] }, { "uniprot_ac": "E1BW33", "gene_name": "SMG1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BW33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BW33" } ] } ] }, { "uniprot_ac": "E1BWA3", "gene_name": "PRKCI", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1BWA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWA3" } ] } ] }, { "uniprot_ac": "E1BWT0", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BWT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BWT0" } ] } ] }, { "uniprot_ac": "E1BX69", "gene_name": "EIF2AK3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BX69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BX69" } ] } ] }, { "uniprot_ac": "E1BY69", "gene_name": "PIM3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BY69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BY69" } ] } ] }, { "uniprot_ac": "E1BYH2", "gene_name": "TAOK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1BYH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1BYH2" } ] } ] }, { "uniprot_ac": "E1C093", "gene_name": "PIK3CG", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "E1C093", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C093" } ] } ] }, { "uniprot_ac": "E1C2I2", "gene_name": "MASTL", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C2I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C2I2" } ] } ] }, { "uniprot_ac": "E1C581", "gene_name": "TBK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C581", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C581" } ] } ] }, { "uniprot_ac": "E1C6T4", "gene_name": "PRKD3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E1C6T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C6T4" } ] } ] }, { "uniprot_ac": "E1C764", "gene_name": "BMP2K", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E1C764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C764" } ] } ] }, { "uniprot_ac": "E1C848", "gene_name": "MAP3K8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E1C848", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E1C848" } ] } ] }, { "uniprot_ac": "F1NA68", "gene_name": "CDK3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1NA68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NA68" } ] } ] }, { "uniprot_ac": "F1NB57", "gene_name": "PLK2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NB57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NB57" } ] } ] }, { "uniprot_ac": "F1NBT0", "gene_name": "STK10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NBT0" } ] } ] }, { "uniprot_ac": "F1NCX7", "gene_name": "PLK1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "F1NCX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCX7" } ] } ] }, { "uniprot_ac": "F1NCY7", "gene_name": "MAPKAPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NCY7" } ] } ] }, { "uniprot_ac": "F1NJH1", "gene_name": "PRKCH", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "F1NJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NJH1" } ] } ] }, { "uniprot_ac": "F1NKW3", "gene_name": "MAP3K15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1NKW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NKW3" } ] } ] }, { "uniprot_ac": "F1NLR7", "gene_name": "CLK3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "F1NLR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NLR7" } ] } ] }, { "uniprot_ac": "F1NUX4", "gene_name": "MTOR", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1NUX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NUX4" } ] } ] }, { "uniprot_ac": "F1NVF2", "gene_name": "MAP2K6", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "F1NVF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1NVF2" } ] } ] }, { "uniprot_ac": "F1P011", "gene_name": "CAMK2A", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "F1P011", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P011" } ] } ] }, { "uniprot_ac": "F1P356", "gene_name": "NUAK1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P356", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P356" } ] } ] }, { "uniprot_ac": "F1P4G3", "gene_name": "HIPK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1P4G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1P4G3" } ] } ] }, { "uniprot_ac": "P05625", "gene_name": "RAF1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P05625", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05625" } ] } ] }, { "uniprot_ac": "P10741", "gene_name": "MOS", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P10741", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P10741" } ] } ] }, { "uniprot_ac": "P13863", "gene_name": "CDK1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "P13863", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P13863" } ] } ] }, { "uniprot_ac": "P18652", "gene_name": "RPS6KA", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P18652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18652" } ] } ] }, { "uniprot_ac": "P21868", "gene_name": "CSNK2A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21868", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21868" } ] } ] }, { "uniprot_ac": "P21869", "gene_name": "", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P21869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P21869" } ] } ] }, { "uniprot_ac": "P53666", "gene_name": "LIMK2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P53666", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P53666" } ] } ] }, { "uniprot_ac": "P67962", "gene_name": "CSNK1A1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P67962", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P67962" } ] } ] }, { "uniprot_ac": "P79996", "gene_name": "MAPK9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "P79996", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P79996" } ] } ] }, { "uniprot_ac": "Q04982", "gene_name": "BRAF", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q04982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q04982" } ] } ] }, { "uniprot_ac": "Q0GGW5", "gene_name": "STK11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q0GGW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q0GGW5" } ] } ] }, { "uniprot_ac": "Q5F3L1", "gene_name": "RPS6KA5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5F3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3L1" } ] } ] }, { "uniprot_ac": "Q5F3W3", "gene_name": "MAPK6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "Q5F3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5F3W3" } ] } ] }, { "uniprot_ac": "Q5ZIU3", "gene_name": "DYRK2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": 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This record is derived from a genomic sequence (NC_052535.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_420883.4. 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"MALCGRSALLRPSPRPAARRPRAAEAFVSCSRLRNIQSILTQSSKSQPDGILCILGIDSRYNEGCRELANYLLFGLYNQSNNDFERTGFPEEVLDDIIILIKPDSVHLYCNPVNYNHLLPYVACWRNLHFHCLTENEYEDEEAAEEFKISSFVDMVRDCSRIGIPYSCQGHLQIFDMFIVEKWPIVQAFALEGIGGDGFFTMKYELMDVSVDLWKTYSKMDPVSLEDLLFEDLMTFEHQWTNFFANFDTEIPFILELSESQAGEPFRSYFSHGMISSHITDNSPSRQPFVLFGSHSTKDNLNSGNFNFPSEGHLVRNTGLGGSTAKHMVVQCVSPKGPLACSRTYFFGTTHIPFLGNDNEVHKKPEQVMLLSQIYTAVVEAVLAGIECYAKTSTESKAKEAAEQMLMSVLDSLHLTQMKTALRSKVAFQIQAVNNHGRVTPLNNEDSLSLIKTASMMVFDIPDLLTGRGCLGSVVFSESFLTSQIHVKEKDGSINSETSHIILTAAIPRYASWLVEDSDVKLSEKAQQILKEDKSFLGTLLTGDDGAYIYSSNPQAMPAEGKLYFFSDGILFCDPHHGSISISKDHINSISLYDGDSTGIVAALFVDFKSSLLAHLPIEFHTQDNFLMIALFPKTKIYKAFYSQVFSSWQNQTNSGLSLRVVQEEFLSVEQKRLHSSVQKLFSSLSFPSGERCNELKISAALPELERFMQHFAVSSVSREPVMSAHLPILLQQSETIPDSRAESDKVVITIITGLPGCRSSDLCSFLITFHKEHGRWLVYRQTMDSPECFSAAHFQRYLSGVLEAQQKHSIRQSTYARKSKRLLVVLQGYTDVIDVVQALQTHPDPDVKSSFIIGAVNTCVEPLSCYIEHRLLFPKFLDQCSQGLVSNVIFTSHATEQRHPLLMQLQSLIRAANPAVSFILAENGVVTRNEDIELILSESSFSNPQKIRARYLMYPGWYEGKYGAGSVFPPMVQICVWFSRPLEKTRFVTKCKAIKSLLKPSPFSGNIYHIMGKVKFSDSDKVIEVCHNTSSNSLSLVPVQEGPTPPDSRNDSRDCSGQQEYFLVFIGCSLKEEDIKDWLRETAKQKPQRKALKTRGMLTLQEIKNIH", "length": 1108, "header": "tr|A0A8V0Z467-1|A0A8V0Z4N8_CHICK Computationally mapped isoform of Dynein axonemal assembly factor 9 OS=Gallus gallus OX=9031 GN=DNAAF9 PE=4 SV=1 CANONICAL=A0A8V0Z4N8-1" }, "locus": { "chromosome": "4", "start_pos": 88723363, "end_pos": 88664442, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043536.1", "url": "https://www.ensembl.org/id/ENSGALT00010043536.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025892.1", "url": "https://www.ensembl.org/id/ENSGALP00010025892.1" } ] } }, { "isoform_ac": "A0A8V0Z4N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N8/entry#A0A8V0Z4N8-1", "sequence": { "sequence": "MALCGRSALLRPSPRPAARRPRAAEAFVSCSRLRNIQSILTQSSKSQPDGILCILGIDSRYNEGCRELANYLLFGLYNQSNNDFERTGFPEEVLDDIIILIKPDSVHLYCNPVNYNHLLPYVACWRNLHFHCLTENEYEDEEAAEEFKISSFVDMVRDCSRIGIPYSCQGHLQIFDMFIVEKWPIVQAFALEGIGGDGFFTMKYELMDVSVDLWKTYSKMDPVSLEDLLFEDLMTFEHQWTNFFANFDTEIPFILELSESQAGEPFRSYFSHGMISSHITDNSPSRQPFVLFGSHSTKDNLNSGNFNFPSEGHLVRNTGLGGSTAKHMVVQCVSPKGPLACSRTYFFGTTHIPFLGNDNEVHKKPEQVMLLSQIYTAVVEAVLAGIECYAKTSTESKAKEAAEQMLMSVLDSLHLTQMKTALRSKVAFQIQAVNNHGRVTPLNNEDSLSLIKTASMMVFDIPDLLTGRGCLGSVVFSESFLTSQIHVKEKDGSINSETSHIILTAAIPRYASWLVEDSDVKLSEKAQQILKEDKSFLGTLLTGDDGAYIYSSNPQAMPAEGKLYFFSDGILFCDPHHGSISISKDHINSISLYDGDSTGIVAALFVDFKSSLLAHLPIEFHTQDNFLMIALFPKTKIYKAFYSQVFSSWQNQTNSGLSLRVVQEEFLSVEQKRLHSSVQKLFSSLSFPSGERCNELKISAALPELERFMQHFAVSSVSREPVMSAHLPILLQQSETIPDSRAESDKVVITIITGLPGCRSSDLCSFLITFHKEHGRWLVYRQTMDSPECFSAAHFQRYLSGVLEAQQKHSIRQSTYARKSKRLLVVLQGYTDVIDVVQALQTHPDPDVKSSFIIGAVNTCVEPLSCYIEHRLLFPKFLDQCSQGLVSNVIFTSHATEQRHPLLMQLQSLIRAANPAVSFILAENGVVTRNEDIELILSESSFSNPQKIRARYLMYPGWYEGKYGAGSVFPPMVQICVWFSRPLEKTRFVTKCKAIKSLLKPSPFSGNIYHIMGKVKFSDSDKVIEVCHNTSSNSLSLVPVQEGPTPPDSRNDSRDCSGQQEYFLVFIGCSLKEEDIKDWLRETAKQKPQRKALKTRGMLTLQEIKNIHVKRHLDPLPAGYFYNGTQFVNFFGDKMDYHPLMDQFMNDYLEEANREIEKYNRELEEQEYHDLFEQKT", "length": 1176, "header": "tr|A0A8V0Z4N8-1|A0A8V0Z4N8_CHICK Isoform 1 of Dynein axonemal assembly factor 9 OS=Gallus gallus OX=9031 GN=DNAAF9 PE=4 SV=1 CANONICAL=A0A8V0Z4N8-1" }, "locus": { "chromosome": "4", "start_pos": 88723363, "end_pos": 88661879, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043521.1", "url": "https://www.ensembl.org/id/ENSGALT00010043521.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025879.1", "url": "https://www.ensembl.org/id/ENSGALP00010025879.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1045, "start_aa": "Thr", "end_pos": 1045, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1045", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1029, "end_pos": 1031, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1051, "end_pos": 1053, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1123, "end_pos": 1125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N8" }, { "id": "PF25204", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25204" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DAAF9", "eco_id": "ECO_0000259", "start_pos": 749, "end_pos": 958, "start_aa": "Ile", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z4N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N8" }, { "id": "PF23319", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23319" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DAAF9 CobW C-like", "eco_id": "ECO_0000259", "start_pos": 974, "end_pos": 1041, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z4N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N8" }, { "id": "PF23281", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23281" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DAAF9 N-terminal", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 217, "start_aa": "Arg", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z4N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N8" }, { "id": "PF26246", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26246" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DAAF9 PH", "eco_id": "ECO_0000259", "start_pos": 517, "end_pos": 720, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z4N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N8" }, { "id": "PF25203", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DAAF9 pita-bread-like", "eco_id": "ECO_0000259", "start_pos": 221, "end_pos": 501, "start_aa": "Asp", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1045 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1029, "end_pos": 1031 }, { "start_pos": 1051, "end_pos": 1053 }, { "start_pos": 1123, "end_pos": 1125 }, { "start_pos": 651, "end_pos": 653 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z473-1", "uniprot_ac": "A0A8V0Z473", "uniprot_id": "A0A8V0Z473_CHICK", "mass": { "chemical_mass": 6476.0, "monoisotopic_mass": 6476.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z473", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z473/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z473", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z473" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z473", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z473", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z473", "database": "AlphaFoldDB", "categories": [] }, { "id": "A0A8V0Z473", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z473", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z473-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z473-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VGLYSTLLLYLPSSPSAGKKRSSNPVSCQRDISRCYTECIRKCFPFYLICCCCWSVQ", "length": 57, "header": "tr|A0A8V0Z473-1|A0A8V0Z473_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z473-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z473-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z473/entry#A0A8V0Z473-1", "sequence": { "sequence": "VGLYSTLLLYLPSSPSAGKKRSSNPVSCQRDISRCYTECIRKCFPFYLICCCCWSVQ", "length": 57, "header": "tr|A0A8V0Z473-1|A0A8V0Z473_CHICK 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"integrator complex subunit 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149816" }, "gene_names": [ { "name": "INTS1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496" } ] }, { "name": "INTS1", "type": "synonym", "evidence": [ { "id": "XP_015149816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149816" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496/entry#names_and_taxonomy" } ] }, { "name": "integrator complex subunit 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015149816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149816" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149816.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149816" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z496", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "INTS1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496", "locus": { "chromosome": "14", "start_pos": 2563594, "end_pos": 2590955, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019625", "url": "https://www.ensembl.org/id/ENSGALG00010019625" } ] } } ], "crossref": [ { "id": "416461", "url": "https://www.ncbi.nlm.nih.gov/gene/416461", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416461", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416461", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSEFRFY", "url": "https://omabrowser.org/oma/group/CSEFRFY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z496", "url": "https://www.orthodb.org/?gene=A0A8V0Z496", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21224:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21224:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22928", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22928", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22929", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22929", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015149816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149816", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z496", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z496-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRPKAAAVRRPSAAPKPSAHPPPGDFIALGSKGQGGDGKAAVTLLKPAPAGLPSERKRDAAAALSGPAGLGGLSKRPKLSATPPLSALGRLAEAAVAEKRAISPSIKEPSVIPIEVVPTVLLDEIEAAEAEGNDDRIEGVLCGAAKQLKMNRAKPDTTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASINFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCKTFVDNIQTAFNTKMPPKSMLLHGEVGRSGGDISAGSSPHPSMTEEEDSQSELLIAEEKMSPEQEGQLMPRYDDLAESVEEYVLDMLRDQLNRRQPMDNVSRNLLRLLTATCGYKEVRQMAVQRLEMWLQNPKLTKPAQDLLMSVCMNCNTHSSEDMEVISNLIKIRLKPKVLLNHYMLCVRELLNAHRDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSEQAPKYLAMVFQDLLTTKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEAQYAEMEFKERFVIHITDLLAVSMMLGITAQVKEAGIAWDKGEKKNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRDLPLGPADAMELADHLVKRAAAVQADDVEVLRVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPSLKMLMEMVMTNNYSYPQCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHVLEQVKSLNQSLRLGHLLCRSRHPDFLLNIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADESTSGEEEEEGESKEQRAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLSSSQVASRVLAMKGLSLVLSEGGLRDGEEKDHPMEEDSGDSELLQGYQWLLRDLPRLPLFDSVRATTAVALQQAIHMETDPQTISAYLVYLSQHAPVEEQGQHNDLALDVARLIVERSTIMSHLFSKLSYCAESDAVLVALLSIFSRYIKCMRQSKEGEEVYRWSESQDQVFLRWTSGETATMHILVVHAMVILLTLGPPQAGDGDFYTLLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVSHDPQTLEQNIMDKNYMAHLVEVQHERGATGGQTFHSLLTASLPARRDSAETAKSKSSPESNQGQSRIRALSQVRVLGPEDDLAGIFLQLFPLNPDPRWQNSNLRPLALALQQALGQELAHIRQGNTQVTGITAQLLQAVAALMNSPHSGALVMAMHRHHFISCPLMRQLYQYQRCMPQDTAFSSLFFKVLMQMLQWLDNPAVEDGPLRAQLKGFAVQYSSRHRISDVRGGFLHLTEALTFRHDPDLISSTVRAIIATLKSGEKGNVEPELISKVLQGLIETQSPYLEELLTVLFSATVETTARFPAMKPIAVVSSLLLQDKEETTVKKEVDSCSTEAAWLGPSSGLLNDWLEMLDPEVISSCPDLQQKLLFSWNKAGSQVPSFRPYLLALLTHQSSWTTLHQCIKLLLCRNREQRFDPTASLDFLWACIHIPRIWQGRDQRTPQKRREEFVLHLKASELISMVELILAEAETRYQNTEEASCTLIQSRLPLLLSCSHGDLESMKKVTEYLTSCIQQWGSSSVGKCCQDLLLQIYLQLPEQLVPLPEMLLTSEGARDSSTCKLDALVHRFINLLADTSDSKSSESRVWDANMACRKLAVAHPILLLRHLPMIAALLHGRVHLNFQEFRQQNHLTFFIHVLGILELLQPQVFQNEHQAALWDCLLSFIRLLLNYRKSSRHLAAFISKYVQFIQKYITCNAQAAVSFLQKHSDPLHDLSSDNSDLAMLKSLLAGLSLPSKSSILDRGSEEEKDDEAAAGSLPLVSVSLFTPLTPAEMAPYMKRLSRGQTVEDILEVLTDIDEMSRRRPEILSFFATNLQKLMSSSEESCRNLAFSLALRSIQNNPSIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYSQIDTSSQISEALKVLHMEATI", "length": 2187, "header": "tr|A0A8V0Z496-1|A0A8V0Z496_CHICK Isoform 1 of Integrator complex subunit 1 OS=Gallus gallus OX=9031 GN=INTS1 PE=1 SV=1 CANONICAL=A0A8V0Z496-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z496-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496/entry#A0A8V0Z496-1", "sequence": { "sequence": "MNRPKAAAVRRPSAAPKPSAHPPPGDFIALGSKGQGGDGKAAVTLLKPAPAGLPSERKRDAAAALSGPAGLGGLSKRPKLSATPPLSALGRLAEAAVAEKRAISPSIKEPSVIPIEVVPTVLLDEIEAAEAEGNDDRIEGVLCGAAKQLKMNRAKPDTTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASINFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCKTFVDNIQTAFNTKMPPKSMLLHGEVGRSGGDISAGSSPHPSMTEEEDSQSELLIAEEKMSPEQEGQLMPRYDDLAESVEEYVLDMLRDQLNRRQPMDNVSRNLLRLLTATCGYKEVRQMAVQRLEMWLQNPKLTKPAQDLLMSVCMNCNTHSSEDMEVISNLIKIRLKPKVLLNHYMLCVRELLNAHRDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSEQAPKYLAMVFQDLLTTKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEAQYAEMEFKERFVIHITDLLAVSMMLGITAQVKEAGIAWDKGEKKNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRDLPLGPADAMELADHLVKRAAAVQADDVEVLRVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPSLKMLMEMVMTNNYSYPQCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHVLEQVKSLNQSLRLGHLLCRSRHPDFLLNIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADESTSGEEEEEGESKEQRAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLSSSQVASRVLAMKGLSLVLSEGGLRDGEEKDHPMEEDSGDSELLQGYQWLLRDLPRLPLFDSVRATTAVALQQAIHMETDPQTISAYLVYLSQHAPVEEQGQHNDLALDVARLIVERSTIMSHLFSKLSYCAESDAVLVALLSIFSRYIKCMRQSKEGEEVYRWSESQDQVFLRWTSGETATMHILVVHAMVILLTLGPPQAGDGDFYTLLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVSHDPQTLEQNIMDKNYMAHLVEVQHERGATGGQTFHSLLTASLPARRDSAETAKSKSSPESNQGQSRIRALSQVRVLGPEDDLAGIFLQLFPLNPDPRWQNSNLRPLALALQQALGQELAHIRQGNTQVTGITAQLLQAVAALMNSPHSGALVMAMHRHHFISCPLMRQLYQYQRCMPQDTAFSSLFFKVLMQMLQWLDNPAVEDGPLRAQLKGFAVQYSSRHRISDVRGGFLHLTEALTFRHDPDLISSTVRAIIATLKSGEKGNVEPELISKVLQGLIETQSPYLEELLTVLFSATVETTARFPAMKPIAVVSSLLLQDKEETTVKKEVDSCSTEAAWLGPSSGLLNDWLEMLDPEVISSCPDLQQKLLFSWNKAGSQVPSFRPYLLALLTHQSSWTTLHQCIKLLLCRNREQRFDPTASLDFLWACIHIPRIWQGRDQRTPQKRREEFVLHLKASELISMVELILAEAETRYQNTEEASCTLIQSRLPLLLSCSHGDLESMKKVTEYLTSCIQQWGSSSVGKCCQDLLLQIYLQLPEQLVPLPEMLLTSEGARDSSTCKLDALVHRFINLLADTSDSKSSESRVWDANMACRKLAVAHPILLLRHLPMIAALLHGRVHLNFQEFRQQNHLTFFIHVLGILELLQPQVFQNEHQAALWDCLLSFIRLLLNYRKSSRHLAAFISKYVQFIQKYITCNAQAAVSFLQKHSDPLHDLSSDNSDLAMLKSLLAGLSLPSKSSILDRGSEEEKDDEAAAGSLPLVSVSLFTPLTPAEMAPYMKRLSRGQTVEDILEVLTDIDEMSRRRPEILSFFATNLQKLMSSSEESCRNLAFSLALRSIQNNPSIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYSQIDTSSQISEALKVLHMEATI", "length": 2187, "header": "tr|A0A8V0Z496-1|A0A8V0Z496_CHICK Isoform 1 of Integrator complex subunit 1 OS=Gallus gallus OX=9031 GN=INTS1 PE=1 SV=1 CANONICAL=A0A8V0Z496-1" }, "locus": { "chromosome": "14", "start_pos": 2590890, "end_pos": 2564092, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047349.1", "url": "https://www.ensembl.org/id/ENSGALT00010047349.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028057.1", "url": "https://www.ensembl.org/id/ENSGALP00010028057.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416461", "resource": "KEGG Pathway" }, { "id": "R-GGA-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FYY8-1", "protein_name": "Integrator complex subunit 1 isoform X1", "gene_name": "Ints1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTERASDSRRLLPGEGASARGARAAGRMNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSGLPSERKRDATASLSGTSALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASVNFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEGARSGGELGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRPRYDELTESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTATCGYKEVRLLAVQRLEMWLQNPKLTRPAQDLLMSVCMNCNSHGPEDMDAISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGVAWDKGEKRNLEVLRTFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKALNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADATASGEEDEEGESREQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGGLRDKEEKEPPMEEDVGEADALQGYQWLLRDLPRLPLFDSVRTTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQGPHSDLALDVARLVVERSTIMAHLFSKPSCSTASDAVLSALLSVFSRYVRRMRKSKEGEEVYSWSESQDQVFLRWTSGETATMHILVVHAMVILLTLGPPRAGDGEFHELLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAQDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPESSPEPPPGQGRTRAGTQVPVLGPEDDLAGIFLQIFPLSPDPRWQSSSPRPLALALQQALGQELARVRQGNPEVPGITVRLLQAMATLLSSPHGGTLALAMHHSHFLSCPLMRQLYQYQRAVPQDTGFSSLFLKVLMQILQWLDSPAVEDGPLQAQLKLFATRYSARRRISDVRSGLLHLAEALSFHHDLEVANSTVRAVIATLKSGEKCTVEPELISKVLRGLIEVRSPHLEELLTALFSATAEASCPSSASGPIVVVSSLLLQEKDEPLGPSKQDAEGASTETMRLGPASGLLVDWLETLDPEVVSSCPDLQRRLLFSRRKGKGHISAQVLSFRPYLLALLTHQASWSTLHRCIRILLGKSREQRLDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLHVQGPELLSLVELILSEAETRSQDGDSAARTLIQTRLPLLLSCCRGNNESVGKVTEHLTSCIQQWGDSVLGQRCRDLLLQLYLQRPEVRVPVPEVLLQSEGATSSSICKLDGLIHRFITLLADTSDSRSSESRVADANMACRKLAVAHPILLLRHLPMIAALLHGRTHLNFQEFRQQNHLAFFLHVLGILELLQPRVFQSEHQGALWDCLRSFIRLLLNYRKSSRHLAPFISKFVQFIHKYVACSAPAAVTFLQKHAEPLHDLSFDNSDLVMLKSLLAGLSLPSRDGRTDQGLDEEGEDERSAGSLPLVSVSLSTPLTVADVAPHMKRLSRGQAVEDVLETLSDIDEMSRRRPEVLGFFSTNLQRLMSSAEESCRNLAFSLALRSIQNNPSIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYGQIDTSAQISEALKILHMEAVM", "length": 2222 }, "evidence": [ { "id": "A0A8V0Z496", "url": "https://omabrowser.org/oma/group/A0A8V0Z496/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9TV32-1", "protein_name": "Integrator complex subunit 1", "gene_name": "INTS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQTTESKTASTLLKPAPSGLPSERKRDAAAALAGASALPGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVPPTVLLDEIEAAELEGNDDRLEGVLCGAVKQLKVTRAKPDSVLYLSLMYLAKMKPNIFATEGVIEALCSLLRRDASVSFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEAGRGGGDLSAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRYEELAESVEEYVLDMLRDQLNRRQPIDSVSRNLLRLLTSACGYKEARLMAVQRLEMWLQNPKLTRPAQDLLMSVCMNCSTHGAEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLDMEFKERFVVHVTDVLAVSMMLGITAQVKEAGVAWDKGEKKNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVDVLKVERVQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMAMTNNYSYPPCTLTDEESRTEMINRELQVSQREKQEILAFEGHLAAASTRQTITESSSLLLSQLTSLEPQGPPRRPPPHILDQVKGLNQSLRLGHLLCRSRNPDFLLNIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADEPASGGEEEEGESKEQKARKRQRQQKQKQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVAARVLAMKGLSLVLSEGSLRDGEEKEPPLEEDSGDADALQGYQWLLRDLPRLPLFESVRSTTALALQQAIHMETDPQTISAYLVYLSQHTPVEEQGQHSDLALDVARLIVERSTIMSHLFSKRSCSAESDVVLAALLSIFSRYVQRMRKSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRAGDSEFQALLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAHDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPARRDSTEAPKPKSSPEQPPGQGGTRAVARVRALGPEDDLAGLLLQIFPLSPGPRWKSSHARPAALALQQALGRELARVRQGSPEVPGVAVRLLQALATLLSSPHGGALALAMHRSHVLACPLMRQLCQYQRCAPQDTGFSSLFLKVLVQALQWLDGPSVEAGPLQAQLRLFAAQCSARRRISNVRSGFLHLVEALTFRGDPEAVSSTVRAIVATLRSGEQCDVEPELISKVLRSLIEVRSPHLEELLAALFSTASAVPPSGPVVVVSSLLLPEKEEPLAPGKQEADSCSQEAMLLGPCSGLLVDWLEMLDPEVVGSCPDLQQRLLFSRGKGKGHPGPQVPSFRPYLLALLTHQSSWSTLHQCIRILLGRGREQRFDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLRVQPAELVGLVELILAEAEARSQDGDAGACGLLQARLPLLLSCCRGGDEGIKKVTAHLTSCVQQWGDSVLGKCSRDLLVQLYLQRPDLRVPLPDVLLHSQGATGSSVCKLDGLIHRFITLLADTSDSRASESRVADASMACRKLAVAHPLLLLRHLPMIAALLHGRTHLNFQEFRQQNHLTFFMHVLGVLELLQPQVFQSEHQGALWDCLLSFVRLLRNYRKSSRHLVPFASKFVRFTHKYISCSPAAAVAFLQKHLNVLHDLSLDSSDLVMLKSLLAGLSLPSRDGGADRALDEEGEDESSAGSLPLVSVCIFTPLTAAEMAPYMKRLSRGQTVEDLLEVLSDVDEMSRRRPEILGFFSTSLQRLMSSAEESCRSLAFSLALRSIQNNPGIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYGQMDTSAQISEALRILHLEAMM", "length": 2189 }, "evidence": [ { "id": "A0A8V0Z496", "url": "https://omabrowser.org/oma/group/A0A8V0Z496/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1M8D7-1", "protein_name": "Integrator complex subunit 1", "gene_name": "Ints1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTERASDSRRLLPGDGASSRGARAAGRMNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSGLPSERKRDASASLSGASGLTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASVNFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEGARSGGELGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRPRYDELTESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTATCGYKEVRLLAVQRLEMWLQNPKLTRPAQDLLMSVCMNCNSHGSEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGVAWDKGEKRNLEVLRTFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKALNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADATASGEEDDEGESREQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGGLRDKEEKEPPMEEDVGEADALQGYQWLLRDLPRLPLFDSVRTTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQGPHSDLALDVARLVVERSTIMAHLFSKPSCSTASDAVLSALLSVFSRYVRRMRKSKEGEEVYSWSESQDQVFLRWTSGETATMHILVVHAMVILLTLGPPRSGDSEFSELLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAQDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPESSPEPPPGQGRTRAGTQVPVLGPEDDLAGIFLQIFPLSPDPRWQSSSPRPLALALQQALGQELARVRQGNPEVPGITVRLLQAMATLLSSPHGGTLALAMHHSHFLSCPLMRQLCQYQRAVPQDTGFSSLFLKVLMQILQWLDSPAVEDGPLQAQLKLFATRYSARRRISDVRSGLLHLAEALSFHRDLEVANSTARAVIATLRSGEKCTVEPELISKVLRGLIEVRSPHFEELLTALFSATAETCPSPASGPIVVVSSLLLQERDEPLGPSTQDAEGASTEAMRLGPASGLLVDWLETLDPEVVCSCPDLQWKLLFSRRKGKGHISAQVLSFRPYLLALLTHQASWSTLHRCTRVLLSKSREQRLDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLHVQGPELLSLVELILSEAETRSQDGDSAARTLIQTRLPLLLSCCRSNDESIGKVTEHLTSCIQQWGDSVLGQRCRDLLLQLYLQRPEVRVPVPEVLLQSEGATSSSICKLDGLIHRFITLLADTSDSRSSESRVADANMACRKLAVAHPILLLRHLPMIAALLHGRTHLNFQEFRQQNHLAFYLHVLGILELLQPRVFQSEHQGALWDCLRSFIRLLLNYRKSSRQLAPFISKFVQFIHKYVACSAPAAVAFLQKHAEPLHDLSFDNSDLVMLKSLLAGLSLPSRDGRADQGLDEEGEDERSAGSLPLVSVSLSTPLTVADVAPHMKRLSRGQAVEDVLETLSDIDEMSRRRPEVLGFFSTNLQRLMSSAEESCRNLAFSLALRSIQNNPSIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGMYGQIDTSAQISEALKILHMEAVM", "length": 2221 }, "evidence": [ { "id": "A0A8V0Z496", "url": "https://omabrowser.org/oma/group/A0A8V0Z496/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P4S8-1", "protein_name": "Integrator complex subunit 1", "gene_name": "Ints1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQASESKTTSTLLKPAPSGLPSERKRDASASLSGTSALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASVNFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCRTFVDNIQTAFNTKMPPKSVLLQGEGARSGGELGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRPRYDELTESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTATCGYKEVRLLAVQRLEMWLQNPKLTRPAQDLLMSVCMNCNSHGSEDMDVISHLIKIRLKPKVLLNHYMLCIRELLNAHKDNLGTTIKFVIFNELSNARNPNNMQILYTVLQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGVAWDKGEKRNLEVLRTFQNQIAAIQRDAVWWLHTVVPSVSKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRVLVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVERIQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMINRELQISQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKALNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAADSTASGEEDDEGESREQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGGLRDKEEKEPPMEEDIGETDALQGYQWLLRDLPRLPLFDSVRTTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQGPHSDLALDVARLVVERSTIMAHLFSKPSCSTASDAVLSALLSVFSRYVRRMRKSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRSGDSEFSELLDIWFPEKKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVPRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQYLDQAVAQDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPESSPEPPPGQGRTRAGTQVPVLGPEDDLAGIFLQIFPLSPDPRWQSSSPRPLALALQQALGQELARVRQGNPEVPGITVRLLQAMTTLLSSPHGGTLALAMHHSHFLSCPLMRQLYQYQRAVPQDTGFSSLFLKVLMQILQWLDSPAVEDGPLQAQLKLFATRYSARHRISDVRSGLLHLADALSFHGDLEVANSTARAVIATLRSGEKCPVEPELISKVLRGLIEVRSPHLEELLTALFSATTETSCPSPASGPIVVVSSLLLQEKEELLGPSKQEVEGASTEAMRLGPASGLLVDWLETLDPEVVCSCPDLQWKLLFSRRKGKGHISAQVLSFRPYLLALLTHQASWSTLHCCIRVLLGKSREQRLDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLHVQGPELLSLVELILSEAETRSQDGDSAARTLIQTRLPLLLSCCRSNDESIGKVTEHLTSCIQQWGDSVLGQRCRDLLLQLYLQRPEVRVPVPEVLLQSEGATSSSICKLDGLVHRFITLLADTSDSRSSESRVADANMACRKLAVAHPVLLLRHLPMIAALLHGRTHLNFQEFRQQNHLAFFLHVLGILELLQPRVFQSEHQGALWDCLRSFIRLLLNYRKSSRHLAPFISKFVQFIHKYVGCSAPAAVAFLQKHAEPLHDLSFDNSDLVMLKSLLAGLSLPSRDGRTDQGLDEEGEDERSAGSLPLVSVSLSTPLTVADVAPHMKRLSRGRAVEDVLETLSDIDEMSRRRPEVLGFFSTNLQRLMSSAEESCRNLAFSLALRSIQNNPSIAADFLPTFMYCLGSRDFEVVQTALRNLPEYTLLCQEHAAVLLHRAFLVGVYGQIDTSAQISEALKILHMEAVM", "length": 2195 }, "evidence": [ { "id": "A0A8V0Z496", "url": "https://omabrowser.org/oma/group/A0A8V0Z496/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N201-1", "protein_name": "Integrator complex subunit 1", "gene_name": "INTS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRAKPTTVRRPSAAAKPSGHPPPGDFIALGSKGQANESKTASTLLKPAPSGLPSERKRDAAAALSSASALTGLTKRPKLSSTPPLSALGRLAEAAVAEKRAISPSIKEPSVVPIEVLPTVLLDEIEAAELEGNDDRIEGVLCGAVKQLKVTRAKPDSTLYLSLMYLAKIKPNIFATEGVIEALCSLLRRDASINFKAKGNSLVSVLACNLLMAAYEEDENWPEIFVKVYIEDSLGERIWVDSPHCKTFVDNIQTAFNTRMPPRSVLLQGEAGRVAGDLGAGSSPHPSLTEEEDSQTELLIAEEKLSPEQEGQLMPRYEELAESVEEYVLDMLRDQLNRRQPIDNVSRNLLRLLTSTCGYKEVRLLAVQKLEMWLQNPKLTRPAQDLLMSVCMNCNTHGSEDMDVISHLIKIRLKPKVLLNHFMLCIRELLSAHKDNLGTTIKLVIFNELSSARNPNNMQVLYTALQHSSELAPKFLAMVFQDLLTNKDDYLRASRALLREIIKQTKHEINFQAFCLGLMQERKEPQYLEMEFKERFVVHITDVLAVSMMLGITAQVKEAGIAWDKGEKRNLEVLRSFQNQIAAIQRDAVWWLHTVVPSISKLAPKDYVHCLHKVLFTEQPETYYKWDNWPPESDRNFFLRLCSEVPILEDTLMRILVIGLSRELPLGPADAMELADHLVKRAAAVQADDVEVLKVGRTQLIDAVLNLCTYHHPENIQLPPGYQPPNLAISTLYWKAWPLLLVVAAFNPENIGLAAWEEYPTLKMLMEMVMTNNYSYPPCTLTDEETRTEMLNRELQTAQREKQEILAFEGHLAAASTKQTITESSSLLLSQLTSLDPQGPPRRPPPHILDQVKSLNQSLRLGHLLCRSRNPDFLLHIIQRQASSQSMPWLADLVQSSEGSLDVLPVQCLCEFLLHDAVDDAASGEEDDEGESKEQKAKKRQRQQKQRQLLGRLQDLLLGPKADEQTTCEVLDYFLRRLGSSQVASRVLAMKGLSLVLSEGSLRDGEEKEPPMEEDVGDTDVLQGYQWLLRDLPRLPLFDSVRSTTALALQQAIHMETDPQTISAYLIYLSQHTPVEEQAQHSDLALDVARLVVERSTIMSHLFSKLSPSAASDAVLSALLSIFSRYVRRMRQSKEGEEVYSWSESQDQVFLRWSSGETATMHILVVHAMVILLTLGPPRADDSEFQALLDIWFPEEKPLPTAFLVDTSEEALLLPDWLKLRMIRSEVLRLVDAALQDLEPQQLLLFVQSFGIPVSSMSKLLQFLDQAVAHDPQTLEQNIMDKNYMAHLVEVQHERGASGGQTFHSLLTASLPPRRDSTEAPKPKSSPEQPIGQGRIRVGTQLRVLGPEDDLAGMFLQIFPLSPDPRWQSSSPRPVALALQQALGQELARVVQGSPEVPGITVRVLQALATLLSSPHGGALVMSMHRSHFLACPLLRQLCQYQRCVPQDTGFSSLFLKVLLQMLQWLDSPGVEGGPLRAQLRMLASQASAGRRLSDVRGGLLRLAEALAFRQDLEVVSSTVRAVIATLRSGEQCSVEPDLISKVLQGLIEVRSPHLEELLTAFFSATADAASPFPACKPVVVVSSLLLQEEEPLAGGKPGADGGSLEAVRLGPSSGLLVDWLEMLDPEVVSSCPDLQLRLLFSRRKGKGQAQVPSFRPYLLTLFTHQSSWPTLHQCIRVLLGKSREQRFDPSASLDFLWACIHVPRIWQGRDQRTPQKRREELVLRVQGPELISLVELILAEAETRSQDGDTAACSLIQARLPLLLSCCCGDDESVRKVTEHLSGCIQQWGDSVLGRRCRDLLLQLYLQRPELRVPVPEVLLHSEGAASSSVCKLDGLIHRFITLLADTSDSRALENRGADASMACRKLAVAHPLLLLRHLPMIAALLHGRTHLNFQEFRQQNHLSCFLHVLGLLELLQPHVFRSEHQGALWDCLLSFIRLLLNYRKSSRHLAAFINKFVQFIHKYITYNAPAAISFLQKHADPLHDLSFDNSDLVMLKSLLAGLSLPSRDDRTDRGLDEEGEEESSAGSLPLVSVSLFTPLTAAEMAPYMKRLSRGQTVEDLLEVLSDIDEMSRRRPEILSFFSTNLQRLMSSAEECCRNLAFSLALRSMQNSPSIAAAFLPTFMYCLGSQDFEVVQTALRNLPEYALLCQEHAAVLLHRAFLVGMYGQMDPSAQISEALRILHMEAVM", "length": 2190 }, "evidence": [ { "id": "A0A8V0Z496", "url": "https://omabrowser.org/oma/group/A0A8V0Z496/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W1C5-1", "protein_name": "Integrator complex subunit 1", "gene_name": "IntS1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDRGKGSGSNRSQKKVPLGGELFALGKSVRDDSKSKILPIKGMSSSDRKREASTALASSSKRFRGNLKDAGAPDMSSGSSQCETWEQFAVDCDLDTVVETIYAALEQNDSETVGRLVCGVIKQTTTSSSRSKVDNIALLALIYVAKVQPSIFCTDIVACALLSFLRREANVKMRYNTNLHILFANLLTRGFMEISQWPEVLLRIYIDDAVNERYWADNELCAPLVKNICAAFKTRTPHISLLRWDVSSSLPSGQAHRDSMTVDDDSGDNSTQSLDASPLNTESEPIPDAMCTTKSRFSDAVVQKHVSDAIRDQLNKRQQQDNYTRNFLKFLCTTSGIAEVRCLSISRLELWIHNGKLVKFAQQLLSYICFNIKGRNTQDNEVLLVLVKMRLKTKPLINHYMSCLKEMIFLQPEILSTVMKLVVQNELSNTRNPNNMGMLATMFQTSADQSAATLAEIYQEFLLQRDDCLRTLRVFLRELVRMLRFDVNLVKFCKTFLSEREDLTPQIEMFEFKERIFNSMVDIVCLCMFLSATPQAREASLSLKTNRDTKNNHALLKLYNQMSQIQLDTVSWMYETVPTLFKIPAAEYHQALHKLLLLDSPEQYSRCDQWPSEPERGAILRIISETPIHEETLLRIILIGITKDIPFSIANTFDVLLLVIKRVSGMKATNIPAVQANKFDIIDFLFSMSEYHHPENIRLPAEYEPPKLAIIAFYWKAWLILLMISAHNPSSFGAFCWDHYPTMKMMMEICITNQFNNSSATKDELQIITMERDHILQFETYLAAQTSPHAVITEETAILITQLMLMDPMGTPRKVPSMVLDQLKFLNQTYKLGHLFCRCRKPDLLLDIIQRQGTTQSMPWLSDLVQNSEGDFSHLPVQCLCEFLLFNAHIINEENSRDAELVNFLRNLIFDGNLSHQIVCELLDYIFRRLSSTVKQSRVAALSGLKIIFRHSGDFENEWLLKSLQQIPHFYEVKPFIIPQLRAACQVENCPELIMAYIQFITAHTLNDPVNEMLDHVIDMAQLIVERSTMFQHIIISQEDYDYVPDENRIQTLKCLFVMFNNYIIKLREYHEPYEWTEYPDLLMVQFDDGVQLPLHINIIHAFIILLTYSNSNMPESIPILDYWFPPGRPAPVAFLPSMPQEQVQLLPDWLKLKMIRSSVDRLIEAALNDLTPDQIVLFVQNFGTPVNSMSKLLAMLDTAVLEQFDLVKNAILNKAYLAQLIEIQQARGAKNGHYTVQALDLHSHSQTVPDLPKISVVIQEAVEIDDYDSSDSDDRPTNFLATKEVAQTILTQPDQLTESRSDCRSLIQKLLDMLASPNSNRADVVNAITEVLAVGCSVTMSRHACTFLRTFFSCMLHSDKYHILENALQKNLSMFKHTFADSSLLQKSELYHESLVFMLRNSREIYAQQFKANTALVARKRIVRAIVQSFDQTKDSKTVAKSKSDQLFHNGLFIDWLSEMDPEIVSTQLMKERFLFSKSCSEFRFYLLSLINHQTNWDTIERIAEYLFKNFHEDYDYATVLNYFEALTTNPKLWKGRDKYMSKNVRPDAFFMLRTSELEPFSHFILHEGLSEVKLDSKNYDFKLCSRMNLLFKLTEKRRDLMVKVMEHVEKSSVSDYLKLQVLQQMYIMYPRIKFLKPGKTGEQAYKLQNLKGCQADKVSNNLITCLGSLVGKKDFETLSTDTELLLRKLAASHPLLFLRQLGVLSSIMQGRAQLSMKALREEHHFHRFVQILRTLELLQPTIFEEAYKNEIQNTLSCYFNFFKHHSNVKEACQMLNKFVQMLQAYINYNPSSALLFIEQYVGILKELAAKYTSLGKLQVLVQAVALLQHKSHSATELDDEEVKYEYDLDEHFDVKPSASKPVVTEDPIEVNPQTPIDPSSSRGPLSVLTLGSYSRSNYTDISPHFLDLVKIIKQSNTEDVVLGPMQELECLTSKRFVFINELFERLLNLIFSPSAQIRSIAFIILIRHLKHNPGNSDINLCTLNAYIQCLRDENSSVAATAIDNLPEMSVLLQEHAIDILTVAFSLGLKSCLNTGHQIRKVLQTLVIQHGY", "length": 2053 }, "evidence": [ { "id": "A0A8V0Z496", "url": "https://omabrowser.org/oma/group/A0A8V0Z496/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "U2 snRNA 3'-end processing", "id": "GO:0034474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034474", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z496", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496" } ], "pmid": "" }, { "name": "regulation of transcription elongation by RNA polymerase II", "id": "GO:0034243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034243", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z496", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496" } ], "pmid": "" }, { "name": "RNA polymerase II transcription initiation surveillance", "id": "GO:0160240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160240", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z496", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z496", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496" } ], "pmid": "" }, { "name": "INTAC complex", "id": "GO:0160232", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160232", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z496", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 774, "end_pos": 776, "annotation": "n_glycosylation_sequon" }, { "start_pos": 857, "end_pos": 859, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496" }, { "id": "PF22929", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22929" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 1 INTS2-binding", "eco_id": "ECO_0000259", "start_pos": 970, "end_pos": 1304, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496" }, { "id": "PF22927", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22927" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 1 R3", "eco_id": "ECO_0000259", "start_pos": 1832, "end_pos": 1990, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496" }, { "id": "PF22928", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22928" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 1 R4", "eco_id": "ECO_0000259", "start_pos": 2048, "end_pos": 2149, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z496" }, { "id": "PF12432", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12432" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 1 RPB2-binding", "eco_id": "ECO_0000259", "start_pos": 323, "end_pos": 478, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 345, "end_pos": 347 }, { "start_pos": 774, "end_pos": 776 }, { "start_pos": 857, "end_pos": 859 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4A2-1", "uniprot_ac": "A0A8V0Z4A2", "uniprot_id": "A0A8V0Z4A2_CHICK", "mass": { "chemical_mass": 38324.0, "monoisotopic_mass": 38324.0 }, "refseq": {}, "gene_names": [ { "name": "AJAP1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ] } ], "protein_names": [ { "name": "Adherens junctions associated protein 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "AJAP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2", "locus": { "chromosome": "21", "start_pos": 794810, "end_pos": 832365, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019630", "url": "https://www.ensembl.org/id/ENSGALG00010019630" } ] } } ], "crossref": [ { "id": "A0A8V0Z4A2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4A2", "database": "AlphaFoldDB", "categories": [] }, { "id": "770310", "url": "https://www.ncbi.nlm.nih.gov/gene/770310", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PEANTFP", "url": "https://omabrowser.org/oma/group/PEANTFP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4A2", "url": "https://www.orthodb.org/?gene=A0A8V0Z4A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZBM4", "url": "https://www.orthodb.org/?gene=A0A8V0ZBM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHL6", "url": "https://www.orthodb.org/?gene=A0A8V0ZHL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32422", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32422", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32422:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32422:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15298", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15298", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBM4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZBM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZBM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHL6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNCTVTQRSAPPQRQQRLRRRSAAPYLERGSGCPLGSHAWMLIAMFHLAMDLASCEPAGTRLSPRSAQRHRLPRGVLWSTGGSEEPRRPSPPWPCAPRARRPPPIPLPRARRQLRGRGFAPRDGRPTALPEVIVWGPTGEEDSLESSTLPSIFTTAAATTITTTTAATTAATTVATAPTPSSPAPTPGIEEPRGRPSTAEPAAGHSSGGKDARPPRGLGDTAGLAVHQIITITVSLIMVIAALITTLVLKNCCAQSGAARRNGHQRKITQQEESCQNLTDFTPARVPSSLDIFTAYNETLQCSHECVRTPVPVYTEEALHSPGDYKATFNGNRPSSSDRHLIPVAFVSEKWFEISC", "length": 356, "header": "tr|A0A8V0Z4A2-1|A0A8V0Z4A2_CHICK Isoform 1 of Adherens junctions associated protein 1 OS=Gallus gallus OX=9031 GN=AJAP1 PE=4 SV=1 CANONICAL=A0A8V0Z4A2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2/entry#A0A8V0Z4A2-1", "sequence": { "sequence": "MNCTVTQRSAPPQRQQRLRRRSAAPYLERGSGCPLGSHAWMLIAMFHLAMDLASCEPAGTRLSPRSAQRHRLPRGVLWSTGGSEEPRRPSPPWPCAPRARRPPPIPLPRARRQLRGRGFAPRDGRPTALPEVIVWGPTGEEDSLESSTLPSIFTTAAATTITTTTAATTAATTVATAPTPSSPAPTPGIEEPRGRPSTAEPAAGHSSGGKDARPPRGLGDTAGLAVHQIITITVSLIMVIAALITTLVLKNCCAQSGAARRNGHQRKITQQEESCQNLTDFTPARVPSSLDIFTAYNETLQCSHECVRTPVPVYTEEALHSPGDYKATFNGNRPSSSDRHLIPVAFVSEKWFEISC", "length": 356, "header": "tr|A0A8V0Z4A2-1|A0A8V0Z4A2_CHICK Isoform 1 of Adherens junctions associated protein 1 OS=Gallus gallus OX=9031 GN=AJAP1 PE=4 SV=1 CANONICAL=A0A8V0Z4A2-1" }, "locus": { "chromosome": "21", "start_pos": 828987, "end_pos": 802805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047356.1", "url": "https://www.ensembl.org/id/ENSGALT00010047356.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028062.1", "url": "https://www.ensembl.org/id/ENSGALP00010028062.1" } ] } }, { "isoform_ac": "A0A8V0ZBM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2/entry#A0A8V0ZBM4-1", "sequence": { "sequence": "MWIQRLPGSRSGCPLGSHAWMLIAMFHLAMDLASCEPAGTRLSPRSAQRHRLPRGVLWSTGGSEEPRRPSPPWPCAPRARRPPPIPLPRARRQLRGRGFAPRDGRPTALPEVIVWGPTGEEDSLESSTLPSIFTTAAATTITTTTAATTAATTVATAPTPSSPAPTPGIEEPRGRPSTAEPAAGHSSGGKDARPPRGLGDTAGLAVHQIITITVSLIMVIAALITTLVLKNCCAQSGAARRNGHQRKITQQEESCQNLTDFTPARVPSSLDIFTAYNETLQCSHECVRTPVPVYTEEALHSPGDYKATFNGNRPSSSDRHLIPVAFVSEKWFEISC", "length": 336, "header": "tr|A0A8V0ZBM4-1|A0A8V0Z4A2_CHICK Computationally mapped isoform of Adherens junctions associated protein 1 OS=Gallus gallus OX=9031 GN=AJAP1 PE=4 SV=1 CANONICAL=A0A8V0Z4A2-1" }, "locus": { "chromosome": "21", "start_pos": 831733, "end_pos": 802805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047363.1", "url": "https://www.ensembl.org/id/ENSGALT00010047363.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028065.1", "url": "https://www.ensembl.org/id/ENSGALP00010028065.1" } ] } }, { "isoform_ac": "A0A8V0ZHL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2/entry#A0A8V0ZHL6-1", "sequence": { "sequence": "MRRSGCPLGSHAWMLIAMFHLAMDLASCEPAGTRLSPRSAQRHRLPRGVLWSTGGSEEPRRPSPPWPCAPRARRPPPIPLPRARRQLRGRGFAPRDGRPTALPEVIVWGPTGEEDSLESSTLPSIFTTAAATTITTTTAATTAATTVATAPTPSSPAPTPGIEEPRGRPSTAEPAAGHSSGGKDARPPRGLGDTAGLAVHQIITITVSLIMVIAALITTLVLKNCCAQSGAARRNGHQRKITQQEESCQNLTDFTPARVPSSLDIFTAYNETLQCSHECVRTPVPVYTEEALHSPGDYKATFNGNRPSSSDRHLIPVAFVSEKWFEISC", "length": 329, "header": "tr|A0A8V0ZHL6-1|A0A8V0Z4A2_CHICK Computationally mapped isoform of Adherens junctions associated protein 1 OS=Gallus gallus OX=9031 GN=AJAP1 PE=4 SV=1 CANONICAL=A0A8V0Z4A2-1" }, "locus": { "chromosome": "21", "start_pos": 832234, "end_pos": 802805, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047368.1", "url": "https://www.ensembl.org/id/ENSGALT00010047368.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028068.1", "url": "https://www.ensembl.org/id/ENSGALP00010028068.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 138, "start_aa": "Thr", "end_pos": 138, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr138", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 179, "start_aa": "Thr", "end_pos": 179, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr179", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 186, "start_aa": "Thr", "end_pos": 186, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr186", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A2ALI5-1", "protein_name": "Adherens junction-associated protein 1", "gene_name": "Ajap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWIQQLLGLSSMSIRWPGRSLGSHAWILIAMLQLAVDFPSCDSLGPGPEFRLLSRPQRPQRLWSLRSGPPTRLPTPAWSPRAARAERAHGPIQMQTPRARRAHRPRDQVATLGPKGGLTKPPAATRSSPSLASATASSSIVTAGAAEHQGLLRRGRRHTHDTEFNDFDFRGGRPTTETEFIAWGPTGDEDALESNTFPGGFGPTTVSILQTRKTTVATTTTTTAASTATAMTLQTKGVTESLDPWKRTPVGVSTTEPSTSPSSNGKDIQPPRILGETSGLAVHQIITITVSLIMVIAALITTLVLKNCCAPSGHTRRNSHQRKMNQQEESCQNLTDFTPARVPSSVDIFTAYNETLQCSHECVRASVPVYADETLHSTGEYKSTFNGNRTSSADRHLIPVAFVSEKWFEISC", "length": 412 }, "evidence": [ { "id": "A0A8V0Z4A2", "url": "https://omabrowser.org/oma/group/A0A8V0Z4A2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1MWE4-1", "protein_name": "Adherens junctions associated protein 1", "gene_name": "AJAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWIQQLLGLSSMFIRWPGCSLGSHAWILIAMFQLALDLPTCESLGPGPEFRLLPRPPHRPPRLWSFKSGQPARIPAPVWSPRPPRVERGHSHGQMPSPRARRAHRPRDQEATLGPKGGLAKPPAAAKSSPSLGSSPTSSSSAGASGAPTDQQALLRRGKRHLQGPAFNSFDFRGSRPTTETEFIAWGPTGEEEALESNTFPGFYGPTTVSIFQTRKTTVATTTTTATASTATSVTLQTQGVTEPLDPRSRIPVGVSTTEPSTSPSRDSGQDSQPPRVLGETSGLAVHQIITITVSLIMVIAALITTLVLKNCCAQSGNPRRNSHQRKTNHQEESCQNLTDFTPARVPSSLDIFTAYNETLQCSHECVRASVPVYTDETLHPAGEYKSTFNGNRPSSSDRHLIPVAFVSEKWFEISC", "length": 416 }, "evidence": [ { "id": "A0A8V0Z4A2", "url": "https://omabrowser.org/oma/group/A0A8V0Z4A2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4W8E7-1", "protein_name": "Adherens junction-associated protein 1", "gene_name": "Ajap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWIQQLLGLSSMPIRWPGRSLGSHLWILIAMLQLAVDFPSCDSLGPGPEFRLLSRPQRPQRLWSLRTGPPTRLPTPAWSPRAARAERAHGPIQMQTPRARRAHRPRDQVATLGPKGGLTKPPAATRSSPSLTSASASSSMTAGAAEHQSLLKRGRRHTHDAEFNDFDFHGGRPTTETEFIAWGPTGDEEALESNTFPGGFGPTTVSILQTRKTTMAATTTTTAASTATAMTLQTKGVTESLDPWKRTPVGVSTTEPSTSPSNNGKDIQPPRILGETSGLAVHQIITITVSLIMVIAALITTLVLKNCCAPSGHTRRNSHQRKMNQQEESCQNLTDFTPARVPSSVDIFTAYNETLQCSHECVRASVPVYADETLHSTGEYKSTFNGNRSSSADRHLIPVAFVSEKWFEISC", "length": 411 }, "evidence": [ { "id": "A0A8V0Z4A2", "url": "https://omabrowser.org/oma/group/A0A8V0Z4A2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UKB5-1", "protein_name": "Adherens junction-associated protein 1", "gene_name": "AJAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWIQQLLGLSSMSIRWPGRPLGSHAWILIAMFQLAVDLPACEALGPGPEFWLLPRSPPRPPRLWSFRSGQPARVPAPVWSPRPPRVERIHGQMQMPRARRAHRPRDQAAALVPKAGLAKPPAAAKSSPSLASSSSSSSSAVAGGAPEQQALLRRGKRHLQGDGLSSFDSRGSRPTTETEFIAWGPTGDEEALESNTFPGVYGPTTVSILQTRKTTVAATTTTTTTATPMTLQTKGFTESLDPRRRIPGGVSTTEPSTSPSNNGEVTQPPRILGEASGLAVHQIITITVSLIMVIAALITTLVLKNCCAQSGNTRRNSHQRKTNQQEESCQNLTDFPSARVPSSLDIFTAYNETLQCSHECVRASVPVYTDETLHSTTGEYKSTFNGNRPSSSDRHLIPVAFVSEKWFEISC", "length": 411 }, "evidence": [ { "id": "A0A8V0Z4A2", "url": "https://omabrowser.org/oma/group/A0A8V0Z4A2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" }, { "name": "cell-cell contact zone", "id": "GO:0044291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044291", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein domain specific binding", "id": "GO:0019904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of cell-matrix adhesion", "id": "GO:0001953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001953", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" }, { "name": "negative regulation of wound healing", "id": "GO:0061045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061045", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" }, { "name": "regulation of polarized epithelial cell differentiation", "id": "GO:0030860", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030860", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A2" }, { "id": "PF15298", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15298" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AJAP1/PANP C-terminal", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 333, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 138, 179, 186 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 277, "end_pos": 279 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 2, "end_pos": 4 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4A7-1", "uniprot_ac": "A0A8V0Z4A7", "uniprot_id": "A0A8V0Z4A7_CHICK", "mass": { "chemical_mass": 45454.0, "monoisotopic_mass": 45454.0 }, "refseq": {}, "gene_names": [ { "name": "CYP2AB3", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A7" } ] } ], "protein_names": [ { "name": "Cytochrome P450, family 2, subfamily AB, polypeptide 3", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYP2AB3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A7", "locus": { "chromosome": "9", "start_pos": 15371442, "end_pos": 15377409, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017924", "url": "https://www.ensembl.org/id/ENSGALG00010017924" } ] } } ], "crossref": [ { "id": "A0A8V0Z4A7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4A7", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4A7", "url": "https://www.orthodb.org/?gene=A0A8V0Z4A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300:SF134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300:SF134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAHAEEVAGRPLSRAFRLMTNGNGVMFSNGHLWKQQRRFGLLTMRKMGVGKQNQECQIQEEAHHLVQYLRNTKGKPLDPAVPVTHTVSNVICALILGHRFSIEDKRFLRLVEAVDDISAFANSVSFYVHDQVPWIATHFLTRCKKALASIDTMRALLEEEIGSHKGKVDENQDFIGYYLDQMAKSKEDAGATYDKANLLQTIFDLFLAGTETTATTLRWALLYMVAYPDVQEKVHKELDAVLGSSRLICYKDRKNLPYTNAVIHEIQRYSNIVLIALPRYTVKDTELLGFPIPKDTIVLVNIDSVLSDPEKWETPDQFNPGHFLDKDGNFVHREAFLPFSIGHRACMGELLARLELFIIFCTLLQAFTFTLPDGVNEVSTKFVFSSTKKPPPHQICAIPR", "length": 401, "header": "tr|A0A8V0Z4A7-1|A0A8V0Z4A7_CHICK Isoform 1 of Cytochrome P450, family 2, subfamily AB, polypeptide 3 OS=Gallus gallus OX=9031 GN=CYP2AB3 PE=3 SV=1 CANONICAL=A0A8V0Z4A7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A7/entry#A0A8V0Z4A7-1", "sequence": { "sequence": "MTAHAEEVAGRPLSRAFRLMTNGNGVMFSNGHLWKQQRRFGLLTMRKMGVGKQNQECQIQEEAHHLVQYLRNTKGKPLDPAVPVTHTVSNVICALILGHRFSIEDKRFLRLVEAVDDISAFANSVSFYVHDQVPWIATHFLTRCKKALASIDTMRALLEEEIGSHKGKVDENQDFIGYYLDQMAKSKEDAGATYDKANLLQTIFDLFLAGTETTATTLRWALLYMVAYPDVQEKVHKELDAVLGSSRLICYKDRKNLPYTNAVIHEIQRYSNIVLIALPRYTVKDTELLGFPIPKDTIVLVNIDSVLSDPEKWETPDQFNPGHFLDKDGNFVHREAFLPFSIGHRACMGELLARLELFIIFCTLLQAFTFTLPDGVNEVSTKFVFSSTKKPPPHQICAIPR", "length": 401, "header": "tr|A0A8V0Z4A7-1|A0A8V0Z4A7_CHICK Isoform 1 of Cytochrome P450, family 2, subfamily AB, polypeptide 3 OS=Gallus gallus OX=9031 GN=CYP2AB3 PE=3 SV=1 CANONICAL=A0A8V0Z4A7-1" }, "locus": { "chromosome": "9", "start_pos": 15376235, "end_pos": 15371664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043335.1", "url": "https://www.ensembl.org/id/ENSGALT00010043335.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025758.1", "url": "https://www.ensembl.org/id/ENSGALP00010025758.1" } ] } } ], "glycosylation": [], 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"A0A8V0Z4A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4A7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4A7" } ], "pmid": "" }, { "name": "organic acid metabolic process", "id": "GO:0006082", "url": 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"recommended", "evidence": [ { "id": "A0A8V0Z4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B1" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat domain 14", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TTC14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B1", "locus": { "chromosome": "9", "start_pos": 16889762, "end_pos": 16961936, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018039", "url": "https://www.ensembl.org/id/ENSGALG00010018039" } ] } } ], "crossref": [ { "id": "A0A8V0Z4B1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4B1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4B1", "url": "https://www.orthodb.org/?gene=A0A8V0Z4B1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5W9", "url": "https://www.orthodb.org/?gene=A0A8V0Z5W9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23184:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23184:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4B1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5W9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERELLRQVLSYHGPSLLALLRSEQHDNPDFRGLLPPPGTVFEPPRGALRSPSAWAEEDAELDTEIQRFIAKKADLLFAQSWKPNGPIADNIGENEEYYAVMPPLEQFMEVPGEIRRELFFRDIERGDIVIGRITSIREFGFFMVLMCLGSGFIRQIDDLQISALCPLRDVPSQTNHGDPLSYYQAGDIIRAAVKDVDRYHEKITLSLYSSALPPNLSSTKLGVITSEDLPLHYRRSLEVAKTGETFEEVLHRSPGFANPSLIEYLTEKLGISESNPPSLMRSLQMKNIDEEDFAPALRKKQSESWALNCVKAGVDCFKDGRHVEAMNEYNKALEIDPQNVEALVARGALYATKGSLNKAISDFEIALENCPTHRNARKYLCQTLVERGEQLEEEDKLVNAESYYKKALSLDETFQEAEEALTKVRKRIQKSLEMREKQAAKQEREKEKQVETSAEKLRKLLKEEKRLKKKRKRSTSSSSSSSSSSSSTDSSSDASLSSSSSSDHKKRKKKHRNRSESSRSSKKRSSRASSHYKDQIRKEEWYSPPADTSASFLNQNFEMENLLERQDSLVCPKTEVREKDRHCSLSRTSGDDEDTFGGRSEDSRDSCSSKTQASTSKTERYHKTDRFFSSRRGYSGSYYKSDDKSRMHYFRRSEWDAEGRREHYKKHGWGQDRYYTSPAGSDYSGKSVGKYRSYSSTPLHEGDKRYDSDRHELTQHKNESGRKNRERSYEETNKTKEPDRESTLDDTGQTESGTKRNLPQNLVNIFNQIAEFEREKGSKQKKQQST", "length": 787, "header": "tr|A0A8V0Z4B1-1|A0A8V0Z4B1_CHICK Isoform 1 of Tetratricopeptide repeat domain 14 OS=Gallus gallus OX=9031 GN=TTC14 PE=4 SV=1 CANONICAL=A0A8V0Z4B1-1" }, "isoforms": [ { "isoform_ac": 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repeat domain 14 OS=Gallus gallus OX=9031 GN=TTC14 PE=4 SV=1 CANONICAL=A0A8V0Z4B1-1" }, "locus": { "chromosome": "9", "start_pos": 16898850, "end_pos": 16890222, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043605.1", "url": "https://www.ensembl.org/id/ENSGALT00010043605.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025937.1", "url": "https://www.ensembl.org/id/ENSGALP00010025937.1" } ] } }, { "isoform_ac": "A0A8V0Z5W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B1/entry#A0A8V0Z5W9-1", "sequence": { "sequence": "MERELLRQVLSYHGPSLLALLRSEQHDNPDFRGLLPPPGTVFEPPRGALRSPSAWAEEDAELDTEIQRFIAKKADLLFAQSWKPNGPIADNIGENEEYYAVMPPLEQFMEVPGEIRRELFFRDIERGDIVIGRITSIREFGFFMVLMCLGSGFIRQIDDLQISALCPLRDVPSQTNHGDPLSYYQAGDIIRAAVKDVDRYHEKITLSLYSSALPPNLSSTKLGVITSEDLPLHYRRSLEVAKTGETFEEVLHRSPGFANPSLIEYLTEKLGISESNPPSLMRSLQMKNIDEEDFAPALRKKQSESWALNCVKAGVDCFKDGRHVEAMNEYNKALEIDPQNVEALVARGALYATKGSLNKAISDFEIALENCPTHRNARKYLCQTLVERGEQLEEEDKLVNAESYYKKALSLDETFQEAEEALTKVRKRIQKRKRSTSSSSSSSSSSSSTDSSSDASLSSSSSSDHKKRKKKHRNRSESSRSSKKRSSRASSHYKDQIRKEEWYSPPADTSASFLNQNFEMENLLERQDSLVCPKTEVREKDRHCSLSRTSGDDEDTFGGRSEDSRDSCSSKTQASTSKTERYHKTDRFFSSRRGYSGSYYKSDDKSRMHYFRRSEWDAEGRREHYKKHGWGQDRYYTSPAGSDYSGKSVGKYRSYSSTPLHEGDKRYDSDRHELTQHKNESGRKNRERSYEETNKTKEPDRESTLDDTGQTESGTKRNLPQNLVNIFNQIAEFEREKGSKQKKQQST", "length": 747, "header": "tr|A0A8V0Z5W9-1|A0A8V0Z4B1_CHICK Computationally mapped isoform of Tetratricopeptide repeat domain 14 OS=Gallus gallus OX=9031 GN=TTC14 PE=4 SV=1 CANONICAL=A0A8V0Z4B1-1" }, "locus": { "chromosome": "9", "start_pos": 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"start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B1" }, { "id": "PS50126", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50126" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "S1 motif", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 209, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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}, { "name": "CYP2J2L5", "type": "synonym", "evidence": [ { "id": "NP_001316414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316414" } ] } ], "protein_names": [ { "name": "Cytochrome P450, family 2, subfamily AB, polypeptide 2", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4B7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B7/entry#names_and_taxonomy" } ] }, { "name": "cytochrome P450 2AB2", "type": "synonym", "evidence": [ { "id": "NP_001316414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316414" } ] }, { "name": "cytochrome P450 2J2-like 5", "type": "synonym", "evidence": [ { "id": "NP_001316414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316414" } ] }, { "name": "cytochrome P450, family 2, subfamily AB, polypeptide 2", "type": "synonym", "evidence": [ { "id": "NP_001316414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316414" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103992393, SAMEA103992533 [ECO:0000348] ##Evidence-Data-END## INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JAENSK010000240.1. On Dec 1, 2021 this sequence version replaced NP_001316414.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001316414", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316414" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYP2AB2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B7", "locus": { "chromosome": "9", "start_pos": 15379816, "end_pos": 15385322, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017931", "url": "https://www.ensembl.org/id/ENSGALG00010017931" } ] } } ], "crossref": [ { "id": "A0A8V0Z4B7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4B7", "database": 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"" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4B7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4B7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, 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"MVGAILHLNGRGEQPRYFTPGRRHFRCLHKMPVENPLFFRSAPKMASMRESDTGLWLHNKLGSTDELWAPPSIASLLTASVIDNIRLCFHGLSSAVKLKLLLGMLHLPRRAVDEMKGALTEIVQLATLDSDPWVLMVADILKSFPDTGSLNLDLEEQNPNVQDILGELREKVSEGETSAMLPLECQYLNKNALTTLAGPLTPPVKHFQLKRKPKSATLRAELLLKSTETAQQLKKTAGVPFHAKGRGLVKKIDTTTPLKGIPKQAPFRSTSAPSVFNPSGNRNPIPPSRTPLRKERGVKLLEFSELDMVGAGREAKRRRKTLDTEVVEKQAKEETVVENATPDYAAGLVSTQKLGSLNNEPALPSTSYLPATPSVVPSSSYIPSSETQPAGSAREALQTNRQTEEPAAPNATTTLPAQFKQRTPMYNSNSNPPATTPTSPLTPTTPPAISPAAQAPQVAPQTQQQPPPKKSLSLTREQMYAAQEMFKTANKVTRPEKALILGFMAGSRENPCQEQGDIIQIKLSEHTEDLPKADGTGSTTMLVDTVFEMNYATGEWTRFKKYKPITNVS", "length": 569, "header": "tr|A0A8V0Z4C5-1|A0A8V0Z4C5_CHICK Isoform 1 of Negative elongation factor complex member A OS=Gallus gallus OX=9031 GN=NELFA PE=1 SV=1 CANONICAL=A0A8V0Z4C5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C5/entry#A0A8V0Z4C5-1", "sequence": { "sequence": "MVGAILHLNGRGEQPRYFTPGRRHFRCLHKMPVENPLFFRSAPKMASMRESDTGLWLHNKLGSTDELWAPPSIASLLTASVIDNIRLCFHGLSSAVKLKLLLGMLHLPRRAVDEMKGALTEIVQLATLDSDPWVLMVADILKSFPDTGSLNLDLEEQNPNVQDILGELREKVSEGETSAMLPLECQYLNKNALTTLAGPLTPPVKHFQLKRKPKSATLRAELLLKSTETAQQLKKTAGVPFHAKGRGLVKKIDTTTPLKGIPKQAPFRSTSAPSVFNPSGNRNPIPPSRTPLRKERGVKLLEFSELDMVGAGREAKRRRKTLDTEVVEKQAKEETVVENATPDYAAGLVSTQKLGSLNNEPALPSTSYLPATPSVVPSSSYIPSSETQPAGSAREALQTNRQTEEPAAPNATTTLPAQFKQRTPMYNSNSNPPATTPTSPLTPTTPPAISPAAQAPQVAPQTQQQPPPKKSLSLTREQMYAAQEMFKTANKVTRPEKALILGFMAGSRENPCQEQGDIIQIKLSEHTEDLPKADGTGSTTMLVDTVFEMNYATGEWTRFKKYKPITNVS", "length": 569, "header": "tr|A0A8V0Z4C5-1|A0A8V0Z4C5_CHICK Isoform 1 of Negative elongation factor complex member A OS=Gallus gallus OX=9031 GN=NELFA PE=1 SV=1 CANONICAL=A0A8V0Z4C5-1" }, "locus": { "chromosome": "4", "start_pos": 82701578, "end_pos": 82682498, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010040358.1", "url": "https://www.ensembl.org/id/ENSGALT00010040358.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010023408.1", "url": "https://www.ensembl.org/id/ENSGALP00010023408.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 19, "start_aa": "Thr", "end_pos": 19, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr19", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 372, "start_aa": "Thr", "end_pos": 372, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr372", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-112382", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-112382", "resource": "Reactome", "description": "Formation of RNA Pol II elongation complex" }, { "id": "R-GGA-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-GGA-6796648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6796648", "resource": "Reactome", "description": "TP53 Regulates Transcription of DNA Repair Genes" }, { "id": "R-GGA-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C5" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C5" } ], "pmid": "" }, { "name": "RNA polymerase inhibitor activity", "id": "GO:0140870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140870", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C5" } ], "pmid": "" }, { "name": "NELF complex", "id": "GO:0032021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032021", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription elongation by RNA polymerase II", "id": "GO:0034244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034244", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C5" } ], "pmid": "" }, { "name": "transcription pausing by RNA polymerase II", "id": "GO:0160239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160239", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C5" }, { "id": "PS51838", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51838" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HDAg", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 292, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 19, 372 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 339, "end_pos": 341 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 567, "end_pos": 569 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4C7-1", "uniprot_ac": "A0A8V0Z4C7", "uniprot_id": "A0A8V0Z4C7_CHICK", "mass": { "chemical_mass": 56102.0, "monoisotopic_mass": 56102.0 }, "refseq": { "ac": "NP_001385381", "name": "cytochrome P450, family 2, subfamily AB, polypeptide 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385381" }, "gene_names": [ { "name": "CYP2AB1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7" } ] }, { "name": "CYP2AB1", "type": "synonym", "evidence": [ { "id": "NP_001385381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385381" } ] }, { "name": "CYP2J2L6", "type": "synonym", "evidence": [ { "id": "NP_001385381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385381" } ] } ], "protein_names": [ { "name": "Cytochrome P450, family 2, subfamily AB, polypeptide 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7/entry#names_and_taxonomy" } ] }, { "name": "cytochrome P450 2AB1", "type": "synonym", "evidence": [ { "id": "NP_001385381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385381" } ] }, { "name": "cytochrome P450 2J2-like 6", "type": "synonym", "evidence": [ { "id": "NP_001385381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385381" } ] }, { "name": "cytochrome P450, family 2, subfamily AB, polypeptide 1", "type": "synonym", "evidence": [ { "id": "NP_001385381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385381" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN02738220 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. On Dec 16, 2021 this sequence version replaced XP_025009140.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001385381", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385381" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CYP2AB1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7", "locus": { "chromosome": "9", "start_pos": 15393406, "end_pos": 15388116, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017945", "url": "https://www.ensembl.org/id/ENSGALG00010017945" } ] } } ], "crossref": [ { "id": "A0A8V0Z4C7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4C7", "database": "AlphaFoldDB", "categories": [] }, { "id": "424944", "url": "https://www.ncbi.nlm.nih.gov/gene/424944", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ATIWGRM", "url": "https://omabrowser.org/oma/group/ATIWGRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4C7", "url": "https://www.orthodb.org/?gene=A0A8V0Z4C7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300:SF368", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300:SF368", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001385381", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001385381", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGIVELFVALVASLLILQFLKLQWMRSQLPPGPVPLPIIGNLWLLDFKLRRETLAKLTNIYGNIYTVWMGQTPVVVLNGYKAVKDAIVTHSEETSGRPLTPFYRDMMGEKGIFLTSGHTWKQQRRFGMTIIRSLGFGKNNLEHQIQTEASHLLHIFANTKGRPFNPRTSIVHAIANIICAVVFGHRFSSEDESFSKLIKAVYFVIYFQATIWGRMYDAFPWLMHRFPGPHQKVFAYNDFMHNLVMNEIQMHEREKAGDPQDLIDFYLTQIAKTKDDPTSTFNKDNMVQTVVDLLLGGTETTSTTLLWALLYMVQYPEIQERVQREIEAVLEPSHVISYEDRKRLPYTNAVIHETLRYSNITSVGVPRLCVRNTTLLGFHIKKGTLVLPNLHSVVYDSDHWATPCKFDPNHFLDVDGNFVNKEAFLPFSAGHRVCLGEQMARVELFIFFTNLLRAFTFQLPEGVKEINPEYVLGAILQPHPYEICAVPR", "length": 489, "header": "tr|A0A8V0Z4C7-1|A0A8V0Z4C7_CHICK Isoform 1 of Cytochrome P450, family 2, subfamily AB, polypeptide 1 OS=Gallus gallus OX=9031 GN=CYP2AB1 PE=1 SV=1 CANONICAL=A0A8V0Z4C7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7/entry#A0A8V0Z4C7-1", "sequence": { "sequence": "MLGIVELFVALVASLLILQFLKLQWMRSQLPPGPVPLPIIGNLWLLDFKLRRETLAKLTNIYGNIYTVWMGQTPVVVLNGYKAVKDAIVTHSEETSGRPLTPFYRDMMGEKGIFLTSGHTWKQQRRFGMTIIRSLGFGKNNLEHQIQTEASHLLHIFANTKGRPFNPRTSIVHAIANIICAVVFGHRFSSEDESFSKLIKAVYFVIYFQATIWGRMYDAFPWLMHRFPGPHQKVFAYNDFMHNLVMNEIQMHEREKAGDPQDLIDFYLTQIAKTKDDPTSTFNKDNMVQTVVDLLLGGTETTSTTLLWALLYMVQYPEIQERVQREIEAVLEPSHVISYEDRKRLPYTNAVIHETLRYSNITSVGVPRLCVRNTTLLGFHIKKGTLVLPNLHSVVYDSDHWATPCKFDPNHFLDVDGNFVNKEAFLPFSAGHRVCLGEQMARVELFIFFTNLLRAFTFQLPEGVKEINPEYVLGAILQPHPYEICAVPR", "length": 489, "header": "tr|A0A8V0Z4C7-1|A0A8V0Z4C7_CHICK Isoform 1 of Cytochrome P450, family 2, subfamily AB, polypeptide 1 OS=Gallus gallus OX=9031 GN=CYP2AB1 PE=1 SV=1 CANONICAL=A0A8V0Z4C7-1" }, "locus": { "chromosome": "9", "start_pos": 15393403, "end_pos": 15388311, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043373.1", "url": "https://www.ensembl.org/id/ENSGALT00010043373.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025778.1", "url": "https://www.ensembl.org/id/ENSGALP00010025778.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZZX4-1", "protein_name": "unspecific monooxygenase", "gene_name": "Cyp2ab1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSLFGGMAFLAGSFLLLKLAALCWRRSHLPPGPFPFPLLGNLWQLNFRLHPNMLFQLAQTHGNVFTVWLGSTPIVVLNGFRAVKEALVSNSEQFSGRPLTPFFRDLFGEKGVICSNGLTWRQQRRFCLTTLRELGLGKQALELQLQHEAAELAEVFHQEQGRAFDPQVPIIRSTTRVIGALVFGHHFLSEEPIFLELIRAINLGLAFASTTWRRLYDMFPWALRYLSGPHQKIFQYHEAVRGFIHHEIIRHKLRTPEAPKDFISCYLSQITKAMDDPVSTFSEENLIQVVIDLFLGGTDTTATTLHWAIIYLVHHRAIQERVQQELDEVLGTAQAVCYEDRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTPTWMHGYYVSKGTIILPNLASVLCDPECWETPHQFNPGHFLDKDGDFVTNEAFLPFSAGHRVCPGEQLARMELFLMFATLLRTFRFQLPEGSQGLRLEYVFGGTLQPQPQKICAVPRLSSLSPREP", "length": 498 }, "evidence": [ { "id": "A0A8V0Z4C7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4C7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9STI0-1", "protein_name": "Cytochrome P450, family 706, subfamily A, polypeptide 5", "gene_name": "CYP706A5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMLSNLFPDNAISLTPYAYAVLILTATFSILWYIFKRSPQPPLPPGPRGLPIVGNLPFLDPDLHTYFTKLAQSHGPIFKLNLGSKLTVVVNSPSLASEILKDQDINFSNHDVPLTARAVTYGGLDLVWLPYGAEWRMLRKVCAAKLFSRKTLDSFYELRRKEIRERTRCLYQKGLEKSPVNVGEQLFLTMMNLMMNMLWGGSVKAEDMESVGTEFKGVISEITRLLGVPNVSDFFPMLARFDLQGLVKKMHLYARDLDAILDRAIEQMQRLRSRDGDDGECKDFLQHLMKLRDQEADSDVPITMNHVKAVLMDMVVGGTESSTNTIEFVMAELISNPELMRRAQQELDEVVGKDNIVEESHITSLPYILAVLKETLRLYPTIPLLVPHRPSETALVGGYTIPKNTKIFINVWSIQRDPNVWEYPTEFRPERFLDKKSCDFTGTDYSYLPFGSGRRICAGIALAERMILYTLATLLHSFDWTIPDGHVLDLEEKFGIVLKLKTPLVALPIPRLSNSNFYF", "length": 520 }, "evidence": [ { "id": "A0A8V0Z4C7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4C7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "S4R196-1", "protein_name": "unspecific monooxygenase", "gene_name": "Cyp2ab1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLFSGMAFLAGSCLLLKLATLCWRRSHLPPGPFPFPLLGNLWQLNFQLHPNMLFQLAQTHGSVFTVWLGSTPIVVLSGFRAVKEALVSNSEQFSGRPLTPFFRDLFGEKGVICSNGLTWRQQRRFCLTTLRELGLGKQALEVQLQHEAAELAKVFLQEEGRAFDPQIPIIRSTTRVIGTLVFGHHFLSEEPIFLELIQAINLGLAFASTIWRRLYDMFPWALRHLSGPHQKIFQYHEAVRGFIRHEIIRHKLRTAEAPKDFINCYLSQITKAIDDPVSTFSEENLIQVVIDLFLGGTDTTATTLHWALIYLVHHRAIQERVQQELDEMLGAAQTICYEDRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTSTWMHGYYVPKGTIILPNLASVLYDPECWESPHQFNPGHFLDKDGNFVANEAFLPFSAGHRVCPGEQLARMELFLMFATLLRTFQFQLPEGSQDLGLEYVFGGTLQPQPQKICAVLRQSSLSPREP", "length": 498 }, "evidence": [ { "id": "A0A8V0Z4C7", "url": "https://omabrowser.org/oma/group/A0A8V0Z4C7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7" } ], "pmid": "" }, { "name": "organic acid metabolic process", "id": "GO:0006082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006082", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4C7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4C7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 360, "end_pos": 362 }, { "start_pos": 373, "end_pos": 375 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4D6-1", "uniprot_ac": "A0A8V0Z4D6", "uniprot_id": "A0A8V0Z4D6_CHICK", "mass": { "chemical_mass": 166973.0, "monoisotopic_mass": 166973.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "IgGFc-binding protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D6", "locus": {} } ], "crossref": [ { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339:SF374", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339:SF374", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4D6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDDFTAFPFVLAAITCPANSHYEPCAAACPATCVNPMAPVTCGLPCVEGCVCDSGYLLYNSQCVPSQQCGCWHNGQHYPVGSEFWTDNTCSSKCTCPTRGGKVQCSSASCPAGQFCGVQNGKPECLEHSYGICHVHGDPHYNTFDKVTHNFMGNCTYTLAKVCSNTSVPYFNVEAKNEHRGNPRVSYVREVVVDVYGERITILKQERSRVLVNGEYRTLPVSAAGGAITVSSSGRYVVLETDFSLHVSYDADHSVEVKVPSSYFNLTCGMCGNFNNRREDDYMMPNGQQAADSNALGESWQVPSSDSDPSCGVPPPTEPCPADKEKLYESEQFCGMLTARPGVFESCHAVINPQSYFETCSYDLCAMSGAQEVLCGALEAYADACQAAGVTLLPWRNATFCPLPCSANSYYDPCMTGCPATCVDREAPQNCSKPCMEGCACASGFLLSGDTCVPEARCGCLFEGNYYSEGESFVSENCSRRCRCEASGQMVCSALSCGEEEVCKVQNGQRGCFPASTAVCHIYGDPHYNTFDGKLHHFQGSCNYTVVTACDNSSLGFSITIRNEHRGNPSWTALNSINGALATLPASPTPNVNVSLSGSYVQVSTKLGLQLQFNGDQELLVRVSEKHKGKLCGLCGTYTGSKEDDFRRPDGVVVPDFNDFGASWMVPDDEGQAEVCSPEGNGDCGPPGGPFQPCHAVLPPQAYFESCVYDQCGTGGSTEQLCSDLSSYAEACAAAGVVLGDWSSGTVCGEESVYILFKSSPPAACNFSCTFDVDFCEWVQEPSSSIDWIRHKGPTPSPDTGPSFDHTTGGRNINQHTAVIQAERCPREDGDKCLLRADTRTCVVEGDPHYHTFDKQIHNFMGNCTYTLSKLCESNSSLPFFNVEAANEHRGGNTRVSYVQYVDVDVYGQRIRLGKGGVVLPCTPSVGVQVSSSGFYTMVTTDFGLRVKFDGNHRVEVTLPSTFGQKVCGMCGNYNGMAADDFLNPDGVSGEGSNFCGLLTDTSGPFEVCHAVLSASGYFDTCLYDLCELGLDREALCNSLQSYADACQALGVQIPVWRNATFCPITCPANSHYEPCAAACPATCVSPTAPYNCSLPCVEGCVCDSGYLLYNSQCVPSQQCGCWHNGQHYPVGSEFWTDNTCSSKCTCPTRGGKVQCSSASCPAGQFCGVQNGKPECLEHSYGICHVHGDPHYNTFDKVTHNFMGNCTYTLAKVCSNTSVPYFNVEAKNEHRGNPRVSYVREVVVDVYGERITILKQERSRVLVREWVWRVNGEYRTLPVSAAGGAITVSSSGRYVVLETDFSLHVSYDADHSVEVKVPSSYFNLTCGMCGNFNNRREDDYMMPNGQQAADSNALGESWQVPSSDSDPSCGVPPPTEPCPADKEKLYESEQFCGMLTARPGVFESCHAVINPQSYFETCSYDLCAMSGAQEVLCGALEAYADACQAAGVTLLPWRNATFCPLPCSANSYYDPCMTGCPATCVDREAPQNCSKPCMEGCACASGFLLSGDTCVPEARCGCLFEGNYYSVSENPALSPSPPMALLCISVCA", "length": 1549, "header": "tr|A0A8V0Z4D6-1|A0A8V0Z4D6_CHICK Isoform 1 of IgGFc-binding protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z4D6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4D6/entry#A0A8V0Z4D6-1", "sequence": { "sequence": "MTDDFTAFPFVLAAITCPANSHYEPCAAACPATCVNPMAPVTCGLPCVEGCVCDSGYLLYNSQCVPSQQCGCWHNGQHYPVGSEFWTDNTCSSKCTCPTRGGKVQCSSASCPAGQFCGVQNGKPECLEHSYGICHVHGDPHYNTFDKVTHNFMGNCTYTLAKVCSNTSVPYFNVEAKNEHRGNPRVSYVREVVVDVYGERITILKQERSRVLVNGEYRTLPVSAAGGAITVSSSGRYVVLETDFSLHVSYDADHSVEVKVPSSYFNLTCGMCGNFNNRREDDYMMPNGQQAADSNALGESWQVPSSDSDPSCGVPPPTEPCPADKEKLYESEQFCGMLTARPGVFESCHAVINPQSYFETCSYDLCAMSGAQEVLCGALEAYADACQAAGVTLLPWRNATFCPLPCSANSYYDPCMTGCPATCVDREAPQNCSKPCMEGCACASGFLLSGDTCVPEARCGCLFEGNYYSEGESFVSENCSRRCRCEASGQMVCSALSCGEEEVCKVQNGQRGCFPASTAVCHIYGDPHYNTFDGKLHHFQGSCNYTVVTACDNSSLGFSITIRNEHRGNPSWTALNSINGALATLPASPTPNVNVSLSGSYVQVSTKLGLQLQFNGDQELLVRVSEKHKGKLCGLCGTYTGSKEDDFRRPDGVVVPDFNDFGASWMVPDDEGQAEVCSPEGNGDCGPPGGPFQPCHAVLPPQAYFESCVYDQCGTGGSTEQLCSDLSSYAEACAAAGVVLGDWSSGTVCGEESVYILFKSSPPAACNFSCTFDVDFCEWVQEPSSSIDWIRHKGPTPSPDTGPSFDHTTGGRNINQHTAVIQAERCPREDGDKCLLRADTRTCVVEGDPHYHTFDKQIHNFMGNCTYTLSKLCESNSSLPFFNVEAANEHRGGNTRVSYVQYVDVDVYGQRIRLGKGGVVLPCTPSVGVQVSSSGFYTMVTTDFGLRVKFDGNHRVEVTLPSTFGQKVCGMCGNYNGMAADDFLNPDGVSGEGSNFCGLLTDTSGPFEVCHAVLSASGYFDTCLYDLCELGLDREALCNSLQSYADACQALGVQIPVWRNATFCPITCPANSHYEPCAAACPATCVSPTAPYNCSLPCVEGCVCDSGYLLYNSQCVPSQQCGCWHNGQHYPVGSEFWTDNTCSSKCTCPTRGGKVQCSSASCPAGQFCGVQNGKPECLEHSYGICHVHGDPHYNTFDKVTHNFMGNCTYTLAKVCSNTSVPYFNVEAKNEHRGNPRVSYVREVVVDVYGERITILKQERSRVLVREWVWRVNGEYRTLPVSAAGGAITVSSSGRYVVLETDFSLHVSYDADHSVEVKVPSSYFNLTCGMCGNFNNRREDDYMMPNGQQAADSNALGESWQVPSSDSDPSCGVPPPTEPCPADKEKLYESEQFCGMLTARPGVFESCHAVINPQSYFETCSYDLCAMSGAQEVLCGALEAYADACQAAGVTLLPWRNATFCPLPCSANSYYDPCMTGCPATCVDREAPQNCSKPCMEGCACASGFLLSGDTCVPEARCGCLFEGNYYSVSENPALSPSPPMALLCISVCA", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4E4-1", "uniprot_ac": "A0A8V0Z4E4", "uniprot_id": "A0A8V0Z4E4_CHICK", "mass": { "chemical_mass": 35174.0, "monoisotopic_mass": 35174.0 }, "refseq": { "ac": "XP_424600", "name": "THUMP domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424600" }, "gene_names": [ { "name": "THUMPD1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E4" } ] }, { "name": "THUMPD1", "type": "synonym", "evidence": [ { "id": "XP_424600", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424600" } ] } ], "protein_names": [ { "name": "THUMP domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E4/entry#names_and_taxonomy" } ] }, { "name": "THUMP domain-containing protein 1", "type": "synonym", 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This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_424600", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_424600" } ] }, { "annotation": "Functions as a tRNA-binding adapter to mediate NAT10-dependent tRNA acetylation modifying cytidine to N4-acetylcytidine (ac4C).", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E4#function" }, { "database": "UniProtKB", "id": "ARBA00053258", "url": "https://www.uniprot.org/uniprotkb/ARBA00053258#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": 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"Protein Classification" ] }, { "id": "gga:107049049", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049049", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KRFCDQA", "url": "https://omabrowser.org/oma/group/KRFCDQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4E4", "url": "https://www.orthodb.org/?gene=A0A8V0Z4E4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13452:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13452:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_424600", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z4E4/entry#A0A8V0Z4E4-1", "sequence": { "sequence": "MAAPEAAARKRRLKGHFAARAKRPRGGGRQLEAGMRGILITCNMNERKCVGEAYSLLGEYGDLLYGPEQLSEPAERLSGSEREEEREEEDDDDDAEAALKKEVGQIRASTERQLRRFQSVESGANNVVFIRTRGIEPENLVHHILKDIHTTKKKKTRVILRMLPISGTCKAFLEDMKKYTETFFEPWFKAPNKSTFQIVYKARNNSHMNREEVIKELAGIVGSLNPENKVDLNNPQYTVVVEIIKNVCCLSVVRDYVLFRKYNLQEVVKSNKDDTQQNPSNVSEEQNSTAVKPETMEENLKEVKQEQE", "length": 308, "header": "tr|A0A8V0Z4E4-1|A0A8V0Z4E4_CHICK Isoform 1 of THUMP domain-containing protein 1 OS=Gallus gallus OX=9031 GN=THUMPD1 PE=1 SV=1 CANONICAL=A0A8V0Z4E4-1" }, "locus": { "chromosome": "14", "start_pos": 14993686, "end_pos": 14991103, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043393.1", "url": "https://www.ensembl.org/id/ENSGALT00010043393.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025793.1", "url": "https://www.ensembl.org/id/ENSGALP00010025793.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:107049049", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:107049049", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LLD6-1", "protein_name": "THUMP domain-containing protein 1", "gene_name": "THUMPD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAPVQQPLQPGGGKRKGKAQYLQAKRARRCEGGGPRQLEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFSDKDQQPSGSEGEDDDDVEAALKKEVGDIKASTEMRLRRFQSVESGANNVVFIRTLGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGTFQIVYKSRNNSHMNREEVIKELAGIVGSLNSENKVDLTNPQYTVVVEIIKAVCCLSVVKDYTLLRKYNLQEVVKSAKDSSQLNPKQAAQAGNGKEAKLESGDKSNQNDPAEGKNNQQMVPEKSEELDHTEPTSETQVVSEGEAKPELARQVTEGSELSKNDLS", "length": 359 }, "evidence": [ { "id": "A0A8V0Z4E4", "url": "https://omabrowser.org/oma/group/A0A8V0Z4E4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9VZD8-1", "protein_name": "THUMP domain-containing protein 1 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEPASKKSKMGKNVKFNNNKKKYFHAKRQTLQPGQRGFFATCNINEKACVRECYNLLNHYADILYGSEKPENEPEKKQPEEGAGGDAGEDDPKPAAGGTSDDDDDLEAAAAKCREMLSQRKMRFQNVDTNTTNCVFIRTQLEDPVALGKHIINDIATTGKSMSRFVLRLVPIEVVCRANMPDIITAAGELFDKHFLKEPTSYGIIFNHRYNQQIKRDQIITQLAELVNSKNVGNKVDLKEAKKSIIVEVLRGWCLLSVIDNYLECKKFNLAELANPSDKKSSGEGDSKSETSEVANGNDKEQAESSEESKSNDDENKDSTENDK", "length": 324 }, "evidence": [ { "id": "A0A8V0Z4E4", "url": "https://omabrowser.org/oma/group/A0A8V0Z4E4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA modification", "id": "GO:0006400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006400", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4E4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4E4" }, { "id": "PS51165", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51165" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "THUMP", "eco_id": "ECO_0000259", "start_pos": 147, "end_pos": 254, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 287, "end_pos": 289 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4G2-1", "uniprot_ac": "A0A8V0Z4G2", "uniprot_id": "A0A8V0Z4G2_CHICK", "mass": { "chemical_mass": 37637.0, "monoisotopic_mass": 37637.0 }, "refseq": { "ac": "NP_001265012", "name": "arginine-hydroxylase NDUFAF5, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012" }, "gene_names": [ { "name": "NDUFAF5", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2" } ] }, { "name": "C20ORF7", "type": "synonym", "evidence": [ { "id": "NP_001265012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012" } ] }, { "name": "C3H20orf7", "type": "synonym", "evidence": [ { "id": "NP_001265012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012" } ] }, { "name": "NDUFAF5", "type": "synonym", "evidence": [ { "id": "NP_001265012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012" } ] }, { "name": "bA526K24.2", "type": "synonym", "evidence": [ { "id": "NP_001265012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012" } ] }, { "name": "dJ842G6.1", "type": "synonym", "evidence": [ { "id": "NP_001265012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012" } ] } ], "protein_names": [ { "name": "Arginine-hydroxylase NDUFAF5, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2/entry#names_and_taxonomy" } ] }, { "name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 5", "type": "synonym", "evidence": [ { "id": "NP_001265012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012" } ] }, { "name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5", "type": "synonym", "evidence": [ { "id": "NP_001265012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012" }, { "id": "A0A8V0Z4G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2/entry#names_and_taxonomy" } ] }, { "name": "Putative methyltransferase NDUFAF5", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2/entry#names_and_taxonomy" } ] }, { "name": "arginine-hydroxylase NDUFAF5, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001265012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012" } ] }, { "name": "probable methyltransferase C20orf7, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001265012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01017246.1, HAEK01059870.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000062.1. On Sep 23, 2021 this sequence version replaced NP_001265012.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001265012", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NDUFAF5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2", "locus": { "chromosome": "3", "start_pos": 12280343, "end_pos": 12286116, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018061", "url": "https://www.ensembl.org/id/ENSGALG00010018061" } ] } } ], "crossref": [ { "id": "A0A8V0Z4G2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4G2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416742", "url": "https://www.ncbi.nlm.nih.gov/gene/416742", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050602", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050602", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416742", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416742", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YEVVYGH", "url": "https://omabrowser.org/oma/group/YEVVYGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4G2", "url": "https://www.orthodb.org/?gene=A0A8V0Z4G2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13090", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13090", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13090:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13090:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001265012", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001265012", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAARALWRPGLPVPRGCGRLWAQPGRAAAAVAPPPPSGASPGARSPFDRRLKRKQKNWAALRPRPAECEYLRDEVGSGVADRVLDIPRTFPLALDLGSGRGYIARHLNQEVIEKLVQVDIAENVFKSTSESEIPTVSVVADEECLPFKENTFDLVVSSLSLHWVNDLPKAFREIHQVLKPDGVFIGAMFGGDTLYELRCSLQLAELEREGGFSPHVSPFVAVSDLGHLLSRAGFNTLTVDTDEIQVNYPGLFEVMEDLQGMGESNCSWNRKPLLHRDTMLAAAAIYQEMYGNSDGSVPATFQIFYMIGWKFHESQAKPAQRGSATVSLGDLAKIDKLLHQK", "length": 342, "header": "tr|A0A8V0Z4G2-1|A0A8V0Z4G2_CHICK Isoform 1 of Arginine-hydroxylase NDUFAF5, mitochondrial OS=Gallus gallus OX=9031 GN=NDUFAF5 PE=1 SV=1 CANONICAL=A0A8V0Z4G2-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2/entry#A0A8V0Z4G2-1", "sequence": { "sequence": "MAAARALWRPGLPVPRGCGRLWAQPGRAAAAVAPPPPSGASPGARSPFDRRLKRKQKNWAALRPRPAECEYLRDEVGSGVADRVLDIPRTFPLALDLGSGRGYIARHLNQEVIEKLVQVDIAENVFKSTSESEIPTVSVVADEECLPFKENTFDLVVSSLSLHWVNDLPKAFREIHQVLKPDGVFIGAMFGGDTLYELRCSLQLAELEREGGFSPHVSPFVAVSDLGHLLSRAGFNTLTVDTDEIQVNYPGLFEVMEDLQGMGESNCSWNRKPLLHRDTMLAAAAIYQEMYGNSDGSVPATFQIFYMIGWKFHESQAKPAQRGSATVSLGDLAKIDKLLHQK", "length": 342, "header": "tr|A0A8V0Z4G2-1|A0A8V0Z4G2_CHICK Isoform 1 of Arginine-hydroxylase NDUFAF5, mitochondrial OS=Gallus gallus OX=9031 GN=NDUFAF5 PE=1 SV=1 CANONICAL=A0A8V0Z4G2-1" }, "locus": { "chromosome": "3", "start_pos": 12286095, "end_pos": 12280850, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043682.1", "url": "https://www.ensembl.org/id/ENSGALT00010043682.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025993.1", "url": "https://www.ensembl.org/id/ENSGALP00010025993.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416742", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:416742", "resource": "KEGG Pathway" }, { "id": "R-GGA-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QKW6-1", "protein_name": "Arginine-hydroxylase NDUFAF5, mitochondrial", "gene_name": "NDUFAF5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLQLTRLRLWWRLSPAVGVPAKNLGLRKVASGVSSRGSTSPRALNIFDRDLKRKQKNWAARQPEPMKFDYLKEEVGSRIADRVYDITRDFPLALDVGCGRGYIAQHLNKETVGKFFQTDIAEHALKNTLEMEIPTVSVLADEEFLPFRENTFDLVVSSLSLHWVNDLPRALEQIHYVLKPDGVFIGAMFGGDTLYELRCSLQLAETEREGGFSPHVSPFTAVSDLGHLLGRAGFTTLTVDTDEIQVNYPGMFELMEDLQGMGESNCAWNRKALLHRDTMLAAAAVYGEMYRNEDGSVPATYQIYYMIGWKYHDSQARPAERGSATVSFGELGKINDLMSQGKKSQ", "length": 345 }, "evidence": [ { "id": "A0A8V0Z4G2", "url": "https://omabrowser.org/oma/group/A0A8V0Z4G2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A2APY7-1", "protein_name": "Arginine-hydroxylase NDUFAF5, mitochondrial", "gene_name": "Ndufaf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRKVVLLRLCPLLGRPAVSASSGSRREVASGVPPSGSTSPRALNIFDRELKRKQKNWAARQPDPMKFDYLKEEVGSRIADRVYDIARDFPLALDIGCGRGYIAQHLDKETVGKIFQTDIAEHALKNSLETDIPTVNILADEEFLPFQENTFDLVVSSLSLHWVNDLPRALEQIHYVLKPDGVFVGAMFGGDTLYELRCSLQLAETEREGGFSPHISPFTAVNDLGHLLGRAGFNTLTVDTDEIQVNYPGMFELMEDLKGMGESNCSWNRKALLHRDTMLAAAAVYREMYRNEDGSIPATFQIYHMIGWKYHDSQARPAERGSATVSFGELAKLNDVMSHEKK", "length": 343 }, "evidence": [ { "id": "A0A8V0Z4G2", "url": "https://omabrowser.org/oma/group/A0A8V0Z4G2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B2GV71-1", "protein_name": "Arginine-hydroxylase NDUFAF5, mitochondrial", "gene_name": "Ndufaf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRRVVLSRLYARLGGPAVSAGRGGRRGVASSVPPSGSTSPRALNIFDRELKRKQKNWAARQPEPMKFDYLKEEIGSRIADRVYDIARDFPLALDIGCGRGYIAQHLNKETVGKIFQTDIAEHALKNSIETDIPTVNILADEEFLPFPENTFDLVVSSLSLHWVNDLPRALEQIHYVLKPDGVFVGAMFGGDTLYELRCSLQLAETEREGGFSPHISPFTAVNDLGHLLGRAGFNTLTVDTDEIQVNYPGMFELMEDLKGMGESNCSWNRKALLHRDTMLAAAAVYREMYSNEDGSIPATYQIYHMIGWKYHDSQARPAERGSATVSFGDLARLNDTMSQGKK", "length": 343 }, "evidence": [ { "id": "A0A8V0Z4G2", "url": "https://omabrowser.org/oma/group/A0A8V0Z4G2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MQP4-1", "protein_name": "Arginine-hydroxylase NDUFAF5, mitochondrial", "gene_name": "NDUFAF5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPLLTPLRFSWRRLPAAGVPVKNLGLRTVASGASSPSGASPKAFNIFDRDLKRKQKNWAARQPEPMKFDYLKEEVGSRIADRVYDIARDFRLALDVGCGRGYVAEHLNKETVGKFFQTDIAENALKNALETEIPTVSVLADEEFLPFRENTFDLVVSSLSLHWVNDLPRALEQIHYVLKPDGVFIGAMFGGDTLFELRCSLQLAETEREGGFSPHVSPFTAVNDLGHLLGRAGFNTLTVDTDEIQVNYPGMFELMEDLQGMGESNCAWNRKALLHRDTMLAAAAVYQEMYRNEDGSVPATYQIYYMIGWKYHDSQARPAERGSATVSFGELGKINDLMSQGKKSQ", "length": 345 }, "evidence": [ { "id": "A0A8V0Z4G2", "url": "https://omabrowser.org/oma/group/A0A8V0Z4G2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O80543-1", "protein_name": "Putative methyltransferase At1g22800, mitochondrial", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRRINSLYGRIGLLKRVPEKSTKQAHTFLASLSFSTEGAYGGDGEFQQNSSKVKIFDRDLKRIHRDRAAWLSRQKNDSFVDAVADNLLDRLEDCKKSFPTAFCLGGSLGAVKRLLRGRGGIEKLIMMDTSYDMIKSCRDAQDDSLDNSIETSYFVGDEEFLPVKESSVDLIISSLGLHWTNDLPGSMIQCKLALKPDGLFLAAILGGETLKELRIACTLAHMEREGGISPRLSPLAQVRDAGNLLTRAGFSLPGVDVDEYVVKYKRAMDLIEHLRAMGETNALLERNKILNRETAVATAAIYDSMFATEDGTIPATFQVIYMTGWREHSSHPQAKRRGSATVSFTDLQKQFGGQS", "length": 355 }, "evidence": [ { "id": "A0A8V0Z4G2", "url": "https://omabrowser.org/oma/group/A0A8V0Z4G2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q5TEU4-1", "protein_name": "Arginine-hydroxylase NDUFAF5, mitochondrial", "gene_name": "NDUFAF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRPAGLWRLCRRPWAARVPAENLGRREVTSGVSPRGSTSPRTLNIFDRDLKRKQKNWAARQPEPTKFDYLKEEVGSRIADRVYDIPRNFPLALDLGCGRGYIAQYLNKETIGKFFQADIAENALKNSSETEIPTVSVLADEEFLPFKENTFDLVVSSLSLHWVNDLPRALEQIHYILKPDGVFIGAMFGGDTLYELRCSLQLAETEREGGFSPHISPFTAVNDLGHLLGRAGFNTLTVDTDEIQVNYPGMFELMEDLQGMGESNCAWNRKALLHRDTMLAAAAVYREMYRNEDGSVPATYQIYYMIGWKYHESQARPAERGSATVSFGELGKINNLMPPGKKSQ", "length": 345 }, "evidence": [ { "id": "A0A8V0Z4G2", "url": "https://omabrowser.org/oma/group/A0A8V0Z4G2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2" } ], "pmid": "" }, { "name": "matrix side of mitochondrial inner membrane", "id": "GO:0099617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099617", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2" } ], "pmid": "" }, { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4G2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G2" }, { "id": "PF08241", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08241" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase type 11", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 186, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4G7-1", "uniprot_ac": "A0A8V0Z4G7", "uniprot_id": "A0A8V0Z4G7_CHICK", "mass": { "chemical_mass": 47113.0, "monoisotopic_mass": 47113.0 }, "refseq": { "ac": "XP_001232943", "name": "transmembrane protein 184A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232943" }, "gene_names": [ { "name": "TMEM184A", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G7" } ] }, { "name": "TMEM184A", "type": "synonym", "evidence": [ { "id": "XP_001232943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232943" } ] } ], "protein_names": [ { "name": "Transmembrane protein 184A", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G7/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 184A", "type": "synonym", "evidence": [ { "id": "XP_001232943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232943" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 16, 2011 this sequence version replaced XP_001232943.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001232943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232943" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4G7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G7" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TMEM184A", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G7", "locus": { "chromosome": "14", "start_pos": 2617667, "end_pos": 2625340, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019683", "url": "https://www.ensembl.org/id/ENSGALG00010019683" } ] } } ], "crossref": [ { "id": "A0A8V0Z4G7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4G7", "database": "AlphaFoldDB", "categories": [] }, { "id": "769655", "url": "https://www.ncbi.nlm.nih.gov/gene/769655", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:769655", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769655", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WPFNRWF", "url": "https://omabrowser.org/oma/group/WPFNRWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4G7", "url": "https://www.orthodb.org/?gene=A0A8V0Z4G7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23423", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23423", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001232943", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001232943", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4G7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNATRAWPSPAAPSSPGPGTAARLASATPSPALTLLTAAHNNSQDGQQLFLTTTTARVISGVFVWSALIVTFHQIYMHLRNYTIPKEQRYIIRILFIVPIYAFDSWLSLLLLGSHQYYVYFDSVRDCYEAFVIYSFLSLCFEYLGGESTIMTEIRGKPIASSCLYGTCCLQGMSYSIGFLRFCKQATLQFCIVKPLMAIVTIILQAFGKYHDGDFNVRSGYLYITIIYNFSVSLALYALFLFYFATMDLLRPFEPVLKFLTIKAVIFLSFWQGTLLAILEKCGVIPEVQIIDGKEVGAGTVAAGYQNFIICIEMLFASIALRYAFSCRVYREKKENSTANLAPMQSISSGLKETMSPQDIVQDAIHNFSPTYQQYTQQAMQEAEHKAPGENGHVACRAEGAGGRKSKNIEKRVLILSDEEL", "length": 422, "header": "tr|A0A8V0Z4G7-1|A0A8V0Z4G7_CHICK Isoform 1 of Transmembrane protein 184A OS=Gallus gallus OX=9031 GN=TMEM184A PE=4 SV=1 CANONICAL=A0A8V0Z4G7-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G7/entry#A0A8V0Z4G7-1", "sequence": { "sequence": "MSNATRAWPSPAAPSSPGPGTAARLASATPSPALTLLTAAHNNSQDGQQLFLTTTTARVISGVFVWSALIVTFHQIYMHLRNYTIPKEQRYIIRILFIVPIYAFDSWLSLLLLGSHQYYVYFDSVRDCYEAFVIYSFLSLCFEYLGGESTIMTEIRGKPIASSCLYGTCCLQGMSYSIGFLRFCKQATLQFCIVKPLMAIVTIILQAFGKYHDGDFNVRSGYLYITIIYNFSVSLALYALFLFYFATMDLLRPFEPVLKFLTIKAVIFLSFWQGTLLAILEKCGVIPEVQIIDGKEVGAGTVAAGYQNFIICIEMLFASIALRYAFSCRVYREKKENSTANLAPMQSISSGLKETMSPQDIVQDAIHNFSPTYQQYTQQAMQEAEHKAPGENGHVACRAEGAGGRKSKNIEKRVLILSDEEL", "length": 422, "header": "tr|A0A8V0Z4G7-1|A0A8V0Z4G7_CHICK Isoform 1 of Transmembrane protein 184A OS=Gallus gallus OX=9031 GN=TMEM184A PE=4 SV=1 CANONICAL=A0A8V0Z4G7-1" }, "locus": { "chromosome": "14", "start_pos": 2622832, "end_pos": 2618992, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047506.1", "url": "https://www.ensembl.org/id/ENSGALT00010047506.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028129.1", "url": "https://www.ensembl.org/id/ENSGALP00010028129.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 29, "start_aa": "Thr", "end_pos": 29, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr29", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:769655", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:769655", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4G7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4G7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4G7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4H9-1", "uniprot_ac": "A0A8V0Z4H9", "uniprot_id": "A0A8V0Z4H9_CHICK", "mass": { "chemical_mass": 25044.0, "monoisotopic_mass": 25044.0 }, "refseq": { "ac": "XP_025011015", "name": "BRICHOS domain-containing protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011015" }, "gene_names": [ { "name": "BRICD5", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H9" } ] }, { "name": "BRICD5", "type": "synonym", "evidence": [ { "id": "XP_025011015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011015" } ] } ], "protein_names": [ { "name": "BRICHOS domain containing 5", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H9/entry#names_and_taxonomy" } ] }, { "name": "BRICHOS domain-containing protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_025011015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011015" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_025011015.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025011015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011015" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "BRICD5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H9", "locus": { "chromosome": "14", "start_pos": 6492585, "end_pos": 6497668, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018080", "url": "https://www.ensembl.org/id/ENSGALG00010018080" } ] } } ], "crossref": [ { "id": "A0A8V0Z4H9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4H9", "database": "AlphaFoldDB", "categories": [] }, { "id": "107054618", "url": "https://www.ncbi.nlm.nih.gov/gene/107054618", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CYRPLEH", "url": "https://omabrowser.org/oma/group/CYRPLEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4H9", "url": "https://www.orthodb.org/?gene=A0A8V0Z4H9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z517", "url": "https://www.orthodb.org/?gene=A0A8V0Z517", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16483", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16483", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_025011015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025011015", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z517", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z517", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z517-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z517-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGGNGPSDAISAGRRLAARFTNPPRTFWVILSIALLFAAVGISTGVILGFSHSSAQAGPQLGRITLHGEQDVPRNQTATVDVSRSTVTYYITSRSNRSAIVLYDSQHGYVCYRPVEQRACYLRTMDPEDRETTQMMLSAAEQRGDTLLLQNNQTKYYREFLGIVAGEQADPKGLGEAIQALCEQTSIFWVQRADGPGKQRLIYLCIDICFPSNICVSICFYYLPE", "length": 226, "header": "tr|A0A8V0Z4H9-1|A0A8V0Z4H9_CHICK Isoform 1 of BRICHOS domain containing 5 OS=Gallus gallus OX=9031 GN=BRICD5 PE=4 SV=1 CANONICAL=A0A8V0Z4H9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H9/entry#A0A8V0Z4H9-1", "sequence": { "sequence": "MEGGNGPSDAISAGRRLAARFTNPPRTFWVILSIALLFAAVGISTGVILGFSHSSAQAGPQLGRITLHGEQDVPRNQTATVDVSRSTVTYYITSRSNRSAIVLYDSQHGYVCYRPVEQRACYLRTMDPEDRETTQMMLSAAEQRGDTLLLQNNQTKYYREFLGIVAGEQADPKGLGEAIQALCEQTSIFWVQRADGPGKQRLIYLCIDICFPSNICVSICFYYLPE", "length": 226, "header": "tr|A0A8V0Z4H9-1|A0A8V0Z4H9_CHICK Isoform 1 of BRICHOS domain containing 5 OS=Gallus gallus OX=9031 GN=BRICD5 PE=4 SV=1 CANONICAL=A0A8V0Z4H9-1" }, "locus": { "chromosome": "14", "start_pos": 6497097, "end_pos": 6493784, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043719.1", "url": "https://www.ensembl.org/id/ENSGALT00010043719.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026013.1", "url": "https://www.ensembl.org/id/ENSGALP00010026013.1" } ] } }, { "isoform_ac": "A0A8V0Z517-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H9/entry#A0A8V0Z517-1", "sequence": { "sequence": "MEGGNGPSDAISAAGPQLGRITLHGEQDVPRNQTATVDVSRSTVTYYITSRSNRSAIVLYDSQHGYVCYRPVEQRACYLRTMDPEDRETTQMMLSAAEQRGDTLLLQNNQTKYYREFLGIVAGEQADPKGLGEAIQALCEQTSIFWVQRADGPGKQRLIYLCIDICFPSNICVSICFYYLPE", "length": 182, "header": "tr|A0A8V0Z517-1|A0A8V0Z517_CHICK Computationally mapped isoform of BRICHOS domain containing 5 OS=Gallus gallus OX=9031 GN=BRICD5 PE=4 SV=1 CANONICAL=A0A8V0Z4H9-1" }, "locus": { "chromosome": "14", "start_pos": 6497097, "end_pos": 6493784, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043716.1", "url": "https://www.ensembl.org/id/ENSGALT00010043716.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026010.1", "url": "https://www.ensembl.org/id/ENSGALP00010026010.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A5F8MPL8-1", "protein_name": "BRICHOS domain containing 5", "gene_name": "Bricd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKQGRIHTESLRSKPAEVKTKPCHRGWRAAGLLLLLTLLTAGAVAGGLLGFMYSSPKPLLQMLRKTFPSSRVPWPNQTTLVDVAQNMATIVVTPFQSNHSWAVLFDGQNGYICYRPAEHQACFLRLMEAQDWETLQLLLNTSRAQESHVPGRDTHYAQELLAVLGGHTVDPTQVGVSVQHLCADTPIYWTQWAEGPQRQRLIYLCIDICFPSNICVSVCFYYLPD", "length": 225 }, "evidence": [ { "id": "A0A8V0Z4H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4H9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A9J7K7L8-1", "protein_name": "BRICHOS domain-containing protein 5 isoform X1", "gene_name": "Bricd5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYSPPKTLLQMLRKTSSSTIPWSNQTTLVDVAQNMATIMVTPLQSNHSWAILFDGQSGYICYRPAEHQACFLRLMEAQDRETLRLLVNTSRVSSTTWLANHPHPPRPGDKQKVLCAAQLGQPRLWFQGNRKLYLLLTKTVDKSRWKGHQAGVGHECPTQSGSRKYYMVAQLSLSAGPRVPYTWPRHPLCPGAAGSFGGTYCGPCPSRSFGATPLLEHSHLLGPTSRG", "length": 227 }, "evidence": [ { "id": "A0A8V0Z4H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4H9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D3ZD16-1", "protein_name": "BRICHOS domain containing 5", "gene_name": "Bricd5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKQGHILTESLRSKPVEVKTKPCYRGWRAAGLLLMLTLLTAGAVAGGLLGFTYSPSKPLLQMLRKTFLSSRVPWPNQTTLVDVAQNMATIMVTPFQSNHSWAVLFDGQSGYICYRPAEHQACFLRLMEAQDWETLQLLLNTSRAQESHVPGQDTHYAQELLAVLGGHAVDPTQVGASVQHLCADTPIYWARWAEGPQRQRLIYLCIDICFPSNICVSVCFYYLPD", "length": 225 }, "evidence": [ { "id": "A0A8V0Z4H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4H9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PL45-1", "protein_name": "BRICHOS domain-containing protein 5", "gene_name": "BRICD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPASCCAERPKPGPTGVKTKPSCGGWRAVSLLLLLLLLVLAAVGVVAGGLLGSAQGPPKPRLQTLRMTLPSPHMPRPNQTILVDVARNAATITVTPPQSNHSWAVLFDGQSGCICYRPEEHQVCFLRLMEDSDRETLRLLVDTSKVQEAWVPSQDTHHTQELLAVQGSLEVDPAQAGALVQRLCMRTPIYWARRAEGESGPLWGKARPSGWFEELGAEPLEIHGTLATGPRRQRLIYLCIDICFPSNICVSVCFYYLPD", "length": 260 }, "evidence": [ { "id": "A0A8V0Z4H9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4H9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4H9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4H9" }, { "id": "PS50869", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50869" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BRICHOS", "eco_id": "ECO_0000259", "start_pos": 94, "end_pos": 191, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 76, "end_pos": 78 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4I5-1", "uniprot_ac": "A0A8V0Z4I5", "uniprot_id": "A0A8V0Z4I5_CHICK", "mass": { "chemical_mass": 87024.0, "monoisotopic_mass": 87024.0 }, "refseq": {}, "gene_names": [ { "name": "MMEL1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I5" } ] } ], "protein_names": [ { "name": "Membrane metalloendopeptidase like 1", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MMEL1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I5", "locus": { "chromosome": "21", "start_pos": 1404327, "end_pos": 1376648, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019692", "url": "https://www.ensembl.org/id/ENSGALG00010019692" } ] } } ], "crossref": [ { "id": "A0A8V0Z4I5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4I5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08662", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08662", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000718", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000718", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042089", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042089", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4I1", "url": "https://www.orthodb.org/?gene=A0A8V0Z4I1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4I5", "url": "https://www.orthodb.org/?gene=A0A8V0Z4I5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZHU4", "url": "https://www.orthodb.org/?gene=A0A8V0ZHU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11733", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11733", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11733:SF141", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11733:SF141", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05649", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05649", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4I1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHU4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZHU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZHU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVTIMGKSESQMDIVEKSTKSGKKSWRFVAIGLAVLLLLMTCSAVALVILYASSRGTQYGTNSGNICTTPGCVTAAARIIQNMDTTADPCKDFYQYACGGWLNRHVIPETSSRYSIFDILRDELEIILKGVLETSDQGDREAFQKAKILYKSCMNESLIEQRDSLPLLEVLTMVGDWPVASADWNSTKEPSWSMEEKLSIMNSRFNKRVLIDMFVWNDDRDSSRHIIYIDQPSLGMPSRDYYFNGGNYQRVREAYLQFMITIAKMIREDMNISKDDLFVQEEMAKVMKLETDIANATTPAEERHDVTLLYNKMTLKELQEKFALNEFNWTFFIQGVMSSVSVQVDPEEEVVVYGMPYLQELKAIISKYSASTIQNYLIWRLVIDRVSSLSRRFKDARASYRKALYGTTLEEARWRECVSYVNNNMENAVGAMYVRETFAGESKRMVQDLIDKIREVFIETLDELQWMDEASKAKAREKALAIKEQIGYPDYILEDQNEKLDQEYANLNFSEHNYFENILENLRAGAQKSLKKLRERVDQDIWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKHQPQALNFGGIGMVIGHEITHGFDDNGRNFDKDGNMFDWWSNFSAMHFKEQSRCMVHQYGNYTWELAGGQNVSGISTLGENIADNGGVRQAYQAYLKWLEQEGKEPMLPGLNLSHKQLFFLNFAQVWCGSYRPEYASQSIKTDVHSPLKYRVMGSLQNFEAFSEVFHCKKGTAMHPADKCRVW", "length": 758, "header": "tr|A0A8V0Z4I5-1|A0A8V0Z4I5_CHICK Isoform 1 of Membrane metalloendopeptidase like 1 OS=Gallus gallus OX=9031 GN=MMEL1 PE=4 SV=1 CANONICAL=A0A8V0Z4I5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I5/entry#A0A8V0Z4I1-1", "sequence": { "sequence": "MENEVGKSVDNQMDKYIVTIMGKSESQMDIVEKSTKSGKKSWRFVAIGLAVLLLLMTCSAVALVILYASSRAARIIQNMDTTADPCKDFYQYACGGWLNRHVIPETSSRYSIFDILRDELEIILKGVLETSDQGDREAFQKAKILYKSCMNESLIEQRDSLPLLEVLTMVGDWPVASADWNSTKEPSWSMEEKLSIMNSRFNKRVLIDMFVWNDDRDSSRHIIYIDQPSLGMPSRDYYFNGGNYQRVREAYLQFMITIAKMIREDMNISKDDLFVQEEMAKVMKLETDIANATTPAEERHDVTLLYNKMTLKELQEKFALNEFNWTFFIQGVMSSVSVQVDPEEEVVVYGMPYLQELKAIISKYSASTIQNYLIWRLVIDRVSSLSRRFKDARASYRKALYGTTLEEARWRECVSYVNNNMENAVGAMYVRETFAGESKRMVQDLIDKIREVFIETLDELQWMDEASKAKAREKALAIKEQIGYPDYILEDQNEKLDQEYANLNFSEHNYFENILENLRAGAQKSLKKLRERVDQDIWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKHQPQALNFGGIGMVIGHEITHGFDDNGRNFDKDGNMFDWWSNFSAMHFKEQSRCMVHQYGNYTWELAGGQNVSGISTLGENIADNGGVRQAYQAYLKWLEQEGKEPMLPGLNLSHKQLFFLNFAQVWCGSYRPEYASQSIKTDVHSPLKYRVMGSLQNFEAFSEVFHCKKGTAMHPADKCRVW", "length": 753, "header": "tr|A0A8V0Z4I1-1|A0A8V0Z4I5_CHICK Computationally mapped isoform of Membrane metalloendopeptidase like 1 OS=Gallus gallus OX=9031 GN=MMEL1 PE=4 SV=1 CANONICAL=A0A8V0Z4I5-1" }, "locus": { "chromosome": "21", "start_pos": 1402066, "end_pos": 1380893, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047535.1", "url": "https://www.ensembl.org/id/ENSGALT00010047535.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028144.1", "url": "https://www.ensembl.org/id/ENSGALP00010028144.1" } ] } }, { "isoform_ac": "A0A8V0Z4I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I5/entry#A0A8V0Z4I5-1", "sequence": { "sequence": "MRVTIMGKSESQMDIVEKSTKSGKKSWRFVAIGLAVLLLLMTCSAVALVILYASSRGTQYGTNSGNICTTPGCVTAAARIIQNMDTTADPCKDFYQYACGGWLNRHVIPETSSRYSIFDILRDELEIILKGVLETSDQGDREAFQKAKILYKSCMNESLIEQRDSLPLLEVLTMVGDWPVASADWNSTKEPSWSMEEKLSIMNSRFNKRVLIDMFVWNDDRDSSRHIIYIDQPSLGMPSRDYYFNGGNYQRVREAYLQFMITIAKMIREDMNISKDDLFVQEEMAKVMKLETDIANATTPAEERHDVTLLYNKMTLKELQEKFALNEFNWTFFIQGVMSSVSVQVDPEEEVVVYGMPYLQELKAIISKYSASTIQNYLIWRLVIDRVSSLSRRFKDARASYRKALYGTTLEEARWRECVSYVNNNMENAVGAMYVRETFAGESKRMVQDLIDKIREVFIETLDELQWMDEASKAKAREKALAIKEQIGYPDYILEDQNEKLDQEYANLNFSEHNYFENILENLRAGAQKSLKKLRERVDQDIWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKHQPQALNFGGIGMVIGHEITHGFDDNGRNFDKDGNMFDWWSNFSAMHFKEQSRCMVHQYGNYTWELAGGQNVSGISTLGENIADNGGVRQAYQAYLKWLEQEGKEPMLPGLNLSHKQLFFLNFAQVWCGSYRPEYASQSIKTDVHSPLKYRVMGSLQNFEAFSEVFHCKKGTAMHPADKCRVW", "length": 758, "header": "tr|A0A8V0Z4I5-1|A0A8V0Z4I5_CHICK Isoform 1 of Membrane metalloendopeptidase like 1 OS=Gallus gallus OX=9031 GN=MMEL1 PE=4 SV=1 CANONICAL=A0A8V0Z4I5-1" }, "locus": { "chromosome": "21", "start_pos": 1402066, "end_pos": 1380900, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047543.1", "url": "https://www.ensembl.org/id/ENSGALT00010047543.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028149.1", "url": "https://www.ensembl.org/id/ENSGALP00010028149.1" } ] } }, { "isoform_ac": "A0A8V0ZHU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I5/entry#A0A8V0ZHU4-1", "sequence": { "sequence": "MGKSESQMDIVEKSTKSGKKSWRFVAIGLAVLLLLMTCSAVALVILYASSRGTQYGTNSGNICTTPGCVTAAARIIQNMDTTADPCKDFYQYACGGWLNRHVIPETSSRYSIFDILRDELEIILKGVLETSDQGDREAFQKAKILYKSCMNESLIEQRDSLPLLEVLTMVGDWPVASADWNSTKEPSWSMEEKLSIMNSRFNKRVLIDMFVWNDDRDSSRHIIYIDQPSLGMPSRDYYFNGGNYQRVREAYLQFMITIAKMIREDMNISKDDLFVQEEMAKVMKLETDIANATTPAEERHDVTLLYNKMTLKELQEKFALNEFNWTFFIQGVMSSVSVQVDPEEEVVVYGMPYLQELKAIISKYSASTIQNYLIWRLVIDRVSSLSRRFKDARASYRKALYGTTLEEARWRECVSYVNNNMENAVGAMYVRETFAGESKRMVQDLIDKIREVFIETLDELQWMDEASKAKAREKALAIKEQIGYPDYILEDQNEKLDQEYANLNFSEHNYFENILENLRAGAQKSLKKLRERVDQDIWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKHQPQALNFGGIGMVIGHEITHGFDDNGRNFDKDGNMFDWWSNFSAMHFKEQSRCMVHQYGNYTWELAGGQNVSGISTLGENIADNGGVRQAYQAYLKWLEQEGKEPMLPGLNLSHKQLFFLNFAQGDGIFAEL", "length": 703, "header": "tr|A0A8V0ZHU4-1|A0A8V0Z4I5_CHICK Computationally mapped isoform of Membrane metalloendopeptidase like 1 OS=Gallus gallus OX=9031 GN=MMEL1 PE=4 SV=1 CANONICAL=A0A8V0Z4I5-1" }, "locus": { "chromosome": "21", "start_pos": 1401993, "end_pos": 1381089, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047549.1", "url": "https://www.ensembl.org/id/ENSGALT00010047549.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028155.1", "url": "https://www.ensembl.org/id/ENSGALP00010028155.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4I5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4I5" } ], "pmid": "" } ] }, { "name": 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aspartase 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025004377" }, "gene_names": [ { "name": "TASP1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3" } ] }, { "name": "C20orf13", "type": "synonym", "evidence": [ { "id": "XP_025004377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025004377" } ] }, { "name": "TASP1", "type": "synonym", "evidence": [ { "id": "XP_025004377", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025004377" } ] } ], "protein_names": [ { "name": "Threonine aspartase 1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3/entry#names_and_taxonomy" } ] }, { "name": "threonine aspartase 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_025004377", "database": "RefSeq", "url": 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This record is derived from a genomic sequence (NC_052534.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_025004377", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_025004377" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TASP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3", "locus": { "chromosome": "3", "start_pos": 12391126, "end_pos": 12318298, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018089", "url": "https://www.ensembl.org/id/ENSGALG00010018089" } ] } } ], "crossref": [ { "id": "A0A8V0Z4J3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4J3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04514", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04514", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416741", "url": "https://www.ncbi.nlm.nih.gov/gene/416741", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000246", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000246", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RLWCAFT", "url": "https://omabrowser.org/oma/group/RLWCAFT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4J3", "url": "https://www.orthodb.org/?gene=A0A8V0Z4J3", "database": 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"MIMEKGISSVEVLPSKSSQVTAVKVVVKEPETKQTQRGKRVGFVLVHAGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVTAALIELEDSPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVANRLLCEGQKGKLSAGRIPPCFLVGEGAFRWAVDHGIPACPPGFSLAAFKRNKRKLELAEKVETDLIQLKKRRQSNEKENDSGTLDTVGAVVVDQEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGARTPYSTAVSTSGCGEHLVRTILARECSCALQTEDAHQALLETMQNKFIGSPFLANEDGVLGGVIVLRSCRCSAEPELSQEKPTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPES", "length": 415, "header": "tr|A0A8V0Z4J3-1|A0A8V0Z4J3_CHICK Isoform 1 of Threonine aspartase 1 OS=Gallus gallus OX=9031 GN=TASP1 PE=3 SV=1 CANONICAL=A0A8V0Z4J3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3/entry#A0A8V0Z4J3-1", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z4J3/entry#A0A8V0Z526-1", "sequence": { "sequence": "MIMEKGISSVEVLPSKSSQVTAVKVVVKEPETKQTQRGKRVGFVLVHAGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVTAALIELEDSPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVANRLLCEGQKGKLSAGRIPPCFLVGEGAFRWAVDHGIPACPPGFSLAAFKRNKRKLELAEKVETDLIQLKKRRQSNEKGSRVMCRTCGRPSKANDGSRGGDQIELYSLENDSGTLDTVGAVVVDQEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGARTPYSTAVSTSGICCFYKYFNMLLKYFLAVCLQKPNKILILIVNYNINVNSIIRSPFLANEDGVLGGVIVLRSCRCSAEPELSQEKPTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPES", "length": 450, "header": "tr|A0A8V0Z526-1|A0A8V0Z526_CHICK Computationally mapped isoform of Threonine aspartase 1 OS=Gallus gallus OX=9031 GN=TASP1 PE=3 SV=1 CANONICAL=A0A8V0Z4J3-1" }, "locus": { "chromosome": "3", "start_pos": 12389675, "end_pos": 12319686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043733.1", "url": "https://www.ensembl.org/id/ENSGALT00010043733.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026020.1", "url": "https://www.ensembl.org/id/ENSGALP00010026020.1" } ] } }, { "isoform_ac": "A0A8V0Z531-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3/entry#A0A8V0Z531-1", "sequence": { "sequence": "MIMEKGISSVEVLPSKSSQVTAVKVVVKEPETKQTQRGKRVGFVLVHAGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVTAALIELEDSPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVANRLLCEGQKGKLSAGRIPPCFLVGEGAFRWAVDHGIPACPPGIMATRFSLAAFKRNKRKLELAEKVETDLIQLKKRRQSNEKGSRVMCRTCGRPSKANDGSRGGDQIELYSLENDSGTLDTVGAVVVDQEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGARTPYSTAVSTSGCGEHLVRTILARECSCALQTEDAHQALLETMQNKFIGSPFLANEDGVLGGVIVLRSCRCSAEPELSQEKPTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPES", "length": 450, "header": "tr|A0A8V0Z531-1|A0A8V0Z531_CHICK Computationally mapped isoform of Threonine aspartase 1 OS=Gallus gallus OX=9031 GN=TASP1 PE=3 SV=1 CANONICAL=A0A8V0Z4J3-1" }, "locus": { "chromosome": "3", "start_pos": 12389675, "end_pos": 12319686, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043744.1", "url": "https://www.ensembl.org/id/ENSGALT00010043744.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026025.1", "url": "https://www.ensembl.org/id/ENSGALP00010026025.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-9772755", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9772755", "resource": "Reactome", "description": "Formation of WDR5-containing histone-modifying complexes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MKA1-1", "protein_name": "Threonine aspartase 1", "gene_name": "Tasp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTMEKGMSSGEGLPSRSPQASAAKVTVKESETRQPCEEKRGGFVLVHAGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVTAALVELEDSPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVANRLLCEGQKGKLSAGRIPPCFLVGEGAYRWAVDHGIPSCPPSIMTTRFSLAAFKRNKRKLELAERVETDFIQLKKRRQSSAKENDSGALDTVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGAHNPYSTAVSTSGCGEHLVRTILARECSHALQAEDAHQALLETMQNKFISSPFLASEDGVLGGVIVLRSCRCSSESDSSQNKQTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPVN", "length": 420 }, "evidence": [ { "id": "A0A8V0Z4J3", "url": "https://omabrowser.org/oma/group/A0A8V0Z4J3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AC58H1R4-1", "protein_name": "Threonine aspartase 1", "gene_name": "tasp1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENLENSSDSKETVSPLNNSGFKLNSTISHRDGKNMGFVLVHAGAGYHSESKAKEYKHVCKRACQKAVDRLRAGGLALEAVTAALVELEDSPFTNAGTGSNLNLSGEVECDASIMDGKSLNYGAVGALSGIKNPVLVSRRLLSETQKGKLSAGRIPPCFLVGKGAEQWAISHGIPACPTEKMTTKFSLSGYKRNKRKMELAEQVETKRRIQSCGHENDFGCLEPVEGEENNSACLDTVGAVVVDWEGNVAAAVSSGGLAMKHPGRVGQAAHYGCGCWAENARDVSLYSTAVSTSGSGEHLIRTMLARECSTAMQAENAHQALLEAMQNKFISSPFLAGEDCVLGGVIVLRCCTCGEAQRSEDIQALLVEFLWSHTTESMCVGYMSAQDSKARTAAICMPSHNKPVFGDRWPRVLGDDTTQSLPFCLLHSGSLRAAYRSLSKSTTRTHISRLPPGAVAGQSLAIEGGVCRLGTASD", "length": 475 }, "evidence": [ { "id": "A0A8V0Z4J3", "url": "https://omabrowser.org/oma/group/A0A8V0Z4J3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O65268-1", "protein_name": "Putative threonine aspartase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMAGDGADQSRRFFVAVHVGAGYHAAANEKALRSVMRRACLAASTILRQDSGECIDAVSAAIQVLEDDPSTNAGRGSNLTEDGHVECDASLMDGDSGMFGGVGAVPGVRNAIKIAALLVKEQITGSTLLGRIPPMLLVGEGARRWGKSKSVLIPGTVTEADQWLVTERARNQWRRFKAMLSEVGAKSILSAEEHPRGTENNETCEENVSSCAAADEDKIMDTVGVICVDNEGHIACGSSSGGIAMKISGRVGLAATYGSGCWASSKGPFGAPFLVGCCVSGAGEYLMRGFAARECCTSLALSQAGPASAAMKVLRSVMHQESSKIGTADKTAGILVVQADASVVVPGSKPELNAVEIAAAYSSLSFGVGYYGNSIEKPKISILRTRRQMSEAGVDHFEARIDLRPTCC", "length": 408 }, "evidence": [ { "id": "A0A8V0Z4J3", "url": "https://omabrowser.org/oma/group/A0A8V0Z4J3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8R1G1-1", "protein_name": "Threonine aspartase 1", "gene_name": "Tasp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIMEKGMNSGEGLPSRSSQASAAKVTVKELETQQPCKEKRGGFVLVHAGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVAAALVELEDSPFTNAGIGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVAHRLLCEGQKGKLSAGRIPPCFLVGEGAYRWAVDHGIPSCPPSTMTTRFSLAAFKRNKRKLELAERVETDFIQLKRRRQSSAKENDSGTLDTVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGAQNPYSTAVSTSGCGEHLVRTILARECSHALQAEDAHQALLETMQNKFISSPFLACEDGVLGGVIVLRSCRCSSESDSSQDKQTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPVN", "length": 420 }, "evidence": [ { "id": "A0A8V0Z4J3", "url": "https://omabrowser.org/oma/group/A0A8V0Z4J3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H6P5-1", "protein_name": "Threonine aspartase 1", "gene_name": "TASP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTMEKGMSSGEGLPSRSSQVSAGKITAKELETKQSYKEKRGGFVLVHAGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVTAALVELEDSPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVANRLLCEGQKGKLSAGRIPPCFLVGEGAYRWAVDHGIPSCPPNIMTTRFSLAAFKRNKRKLELAERVDTDFMQLKKRRQSSEKENDSGTLDTVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGAHNPYSTAVSTSGCGEHLVRTILARECSHALQAEDAHQALLETMQNKFISSPFLASEDGVLGGVIVLRSCRCSAEPDSSQNKQTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPVN", "length": 420 }, "evidence": [ { "id": "A0A8V0Z4J3", "url": "https://omabrowser.org/oma/group/A0A8V0Z4J3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "threonine-type endopeptidase activity", "id": "GO:0004298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004298", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4J3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4J9-1", "uniprot_ac": "A0A8V0Z4J9", "uniprot_id": "A0A8V0Z4J9_CHICK", "mass": { "chemical_mass": 18827.0, "monoisotopic_mass": 18827.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4J9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4J9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J9", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z4J9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4J9", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR19256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19256:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19256:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4J9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4J9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLDLIGRLAVLAVFSLLLIDGHAVPMQSPAEHRLVEGSSVTMTCQLSSGTVVHWYRQLPGEPPKRILYMTGNSPTFDYSNDRQKFQVQRNPSNSVLKIEKSTRRDTGTYYCAYWYYQAIQKVSCEVLHLRVWNFSHTEISIVLVLRGPGHSLSWKSLHAFQSLD", "length": 165, "header": "tr|A0A8V0Z4J9-1|A0A8V0Z4J9_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z4J9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4J9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J9/entry#A0A8V0Z4J9-1", "sequence": { "sequence": "MLLDLIGRLAVLAVFSLLLIDGHAVPMQSPAEHRLVEGSSVTMTCQLSSGTVVHWYRQLPGEPPKRILYMTGNSPTFDYSNDRQKFQVQRNPSNSVLKIEKSTRRDTGTYYCAYWYYQAIQKVSCEVLHLRVWNFSHTEISIVLVLRGPGHSLSWKSLHAFQSLD", "length": 165, "header": "tr|A0A8V0Z4J9-1|A0A8V0Z4J9_CHICK Isoform 1 of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z4J9-1" }, "locus": { "chromosome": "2", "start_pos": 49063456, "end_pos": 49053897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042945.1", "url": "https://www.ensembl.org/id/ENSGALT00010042945.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025435.1", "url": "https://www.ensembl.org/id/ENSGALP00010025435.1" } ] } }, { "isoform_ac": "A0A8V0ZAD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J9/entry#A0A8V0ZAD8-1", "sequence": { "sequence": "VSSPHQQLLLLMFLFFTTDAQAVPMQSPAEHRLVEGSSVTMTCQLSSGTVVHWYRQLPGEPPKRILYMTGNSPTFDYSNDRQKFQVQRNPSNSVLKIEKSTRRDTGTYYCAYWYYQGIWHSEPQALNSQISIVLVLRGPGHSLSWKSLHAFQSLD", "length": 155, "header": "tr|A0A8V0ZAD8-1|A0A8V0Z4J9_CHICK Computationally mapped isoform of Ig-like domain-containing protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z4J9-1" }, "locus": { "chromosome": "2", "start_pos": 49056115, "end_pos": 49053897, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042937.1", "url": "https://www.ensembl.org/id/ENSGALT00010042937.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025427.1", "url": "https://www.ensembl.org/id/ENSGALP00010025427.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4J9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4J9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4J9" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 112, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4K9-1", "uniprot_ac": "A0A8V0Z4K9", "uniprot_id": "A0A8V0Z4K9_CHICK", "mass": { "chemical_mass": 85360.0, "monoisotopic_mass": 85360.0 }, "refseq": { "ac": "NP_001006573", "name": "RNA exonuclease 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006573" }, "gene_names": [ { "name": "REXO5", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9" } ] }, { "name": "EXNEF", "type": "synonym", "evidence": [ { "id": "NP_001006573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006573" } ] }, { "name": "REXO5", "type": "synonym", "evidence": [ { "id": "NP_001006573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006573" } ] } ], "protein_names": [ { "name": "RNA exonuclease 5", "type": "synonym", "evidence": [ { "id": "NP_001006573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006573" }, { "id": "A0A8V0Z4K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9/entry#names_and_taxonomy" } ] }, { "name": "exonuclease NEF-sp", "type": "synonym", "evidence": [ { "id": "NP_001006573", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006573" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AJ719414.1, SRR13267654.241837.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000258.1. On Sep 23, 2021 this sequence version replaced NP_001006573.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006573", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006573" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "REXO5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9", "locus": { "chromosome": "14", "start_pos": 15027485, "end_pos": 15012655, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017993", "url": "https://www.ensembl.org/id/ENSGALG00010017993" } ] } } ], "crossref": [ { "id": "A0A8V0Z4K9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4K9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06145", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06145", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12274", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12274", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "427001", "url": "https://www.ncbi.nlm.nih.gov/gene/427001", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013520", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:427001", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427001", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHICIQY", "url": "https://omabrowser.org/oma/group/PHICIQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4K4", "url": "https://www.orthodb.org/?gene=A0A8V0Z4K4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4K9", "url": "https://www.orthodb.org/?gene=A0A8V0Z4K9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12801", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12801", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12801:SF82", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12801:SF82", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00929", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00929", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006573", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006573", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4K4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGLSGGVNGCKRPAGEDAEGLRAGGKRSRAGRREAKEKSSHLCAALLGEDCEISPEQLHELLQYAALGKHHNAAQPSWCHIYHQSRLAGVVVIVLHEMSQLHFYKFYLQFKHLRKVFQHRFTLPPPSANFLASLCGEGSSLNPQGTAQGLISTGAECIPKSSGLQCDPIIRKYGKEKRGLTSYTLTSEELKKNDYPMRDSPGCKGYMYTECDLQRTDSSPLFGLDCEMCLTARGNEVVRVSLVDAEGQCLLNELVKPESVIVNYCTRYSGVTRKMLLPVKTRLPDIQTRLKKILPHDAVLVGHSLNADLQALQMIHPSVIDTSLLFARNEGRRFKLKFLAKAVLGKEIQCEQRLGHDPAEDARAALELAQFFIKKGPVKVAELNLEMLLAAERQTEVLPKKSVMQPQRCGVQKQLNDTPHLSKPCFLACLQGMGQKPLLLGRQELDSSGFCQSDLSASNKQILQRALEDVPLSTFSIIQFSLDPEYVASHRLAGFCEKVRNKLTDMLTIYAGPFEEDFCLKSVKKEFGKCGPIHSLTVVSETYQPYVCIQYGVLEAAQLAVESLNGAEVAGSCIKVQRPITAATLDCDVLIKELELDIENEGVIYVAGIKKSLTETDLQEEFSPLKDLETLFLPKDLQSGKHSTCCFLKFQKSQSAADALEAINGWAVKGSTLRSRHALASGHLWRWIWQMNHSSEKQGGNSLSEKMAPLSDSEQDVKKKVKKLDHHIKKLYRSLQDNTLCVVLFPGTNSIHGSQSGLGMMGIKDDGGSSAC", "length": 773, "header": "tr|A0A8V0Z4K9-1|A0A8V0Z4K9_CHICK Isoform 1 of RNA exonuclease 5 OS=Gallus gallus OX=9031 GN=REXO5 PE=4 SV=1 CANONICAL=A0A8V0Z4K9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9/entry#A0A8V0Z4K4-1", "sequence": { "sequence": "MAGLSGGVNGCKRPAGEDAEGLRAGGKRSRAGRREAKEKSSHLCAALLGEDCEISPEQLHELLQYAALGKHHNAAQPSWCHIYHQSRLAGVVVIVLHEMSQLHFYKFYLQFKHLRKVFQHRFTLPPPSANFLASLCGEGSSLNPQGTAQGLISTGAECIPKSSGLQCDPIIRKYGKEKRGLTSYTLTSEELKKNDYPMRDSPGCKGYMYTECDLQRTDSSPLFGLDCEMCLTARGNEVVRVSLVDAEGQCLLNELVKPESVIVNYCTRYSGVTRKMLLPVKTRLPDIQTRLKKILPHDAVLMIHPSVIDTSLLFARNEGRRFKLKFLAKAVLGKEIQCEQRLGHDPAEDARAALELAQFFIKKGPVKVAELNLEMLLAAERQTEVLPKKSVMQPQRCGVQKQLNDTPHLSKPCFLACLQGMGQKPLLLGRQELDSSGFCQSDLSASNKQILQRALEDVPLSTFSIIQFSLDPEYVASHRLAGFCEKVRNKLTDMLTIYAGPFEEDFCLKSVKKEFGKCGPIHSLTVVSETYQPYVCIQYGVLEAAQLAVESLNGAEVAGSCIKVQRPITAATLDCDVLIKELELDIENEGVIYVAGIKKSLTETDLQEEFSPLKDLETLFLPKDLQSGKHSTCCFLKFQKSQSAADALEAINGWAVKGSTLRSRHALASGHLWRWIWQMNHSSEKQGGNSLSEKMAPLSDSVSLRLC", "length": 707, "header": "tr|A0A8V0Z4K4-1|A0A8V0Z4K9_CHICK Computationally mapped isoform of RNA exonuclease 5 OS=Gallus gallus OX=9031 GN=REXO5 PE=4 SV=1 CANONICAL=A0A8V0Z4K9-1" }, "locus": { "chromosome": "14", "start_pos": 15025436, "end_pos": 15012891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043476.1", "url": "https://www.ensembl.org/id/ENSGALT00010043476.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025848.1", "url": "https://www.ensembl.org/id/ENSGALP00010025848.1" } ] } }, { "isoform_ac": "A0A8V0Z4K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9/entry#A0A8V0Z4K9-1", "sequence": { "sequence": "MAGLSGGVNGCKRPAGEDAEGLRAGGKRSRAGRREAKEKSSHLCAALLGEDCEISPEQLHELLQYAALGKHHNAAQPSWCHIYHQSRLAGVVVIVLHEMSQLHFYKFYLQFKHLRKVFQHRFTLPPPSANFLASLCGEGSSLNPQGTAQGLISTGAECIPKSSGLQCDPIIRKYGKEKRGLTSYTLTSEELKKNDYPMRDSPGCKGYMYTECDLQRTDSSPLFGLDCEMCLTARGNEVVRVSLVDAEGQCLLNELVKPESVIVNYCTRYSGVTRKMLLPVKTRLPDIQTRLKKILPHDAVLVGHSLNADLQALQMIHPSVIDTSLLFARNEGRRFKLKFLAKAVLGKEIQCEQRLGHDPAEDARAALELAQFFIKKGPVKVAELNLEMLLAAERQTEVLPKKSVMQPQRCGVQKQLNDTPHLSKPCFLACLQGMGQKPLLLGRQELDSSGFCQSDLSASNKQILQRALEDVPLSTFSIIQFSLDPEYVASHRLAGFCEKVRNKLTDMLTIYAGPFEEDFCLKSVKKEFGKCGPIHSLTVVSETYQPYVCIQYGVLEAAQLAVESLNGAEVAGSCIKVQRPITAATLDCDVLIKELELDIENEGVIYVAGIKKSLTETDLQEEFSPLKDLETLFLPKDLQSGKHSTCCFLKFQKSQSAADALEAINGWAVKGSTLRSRHALASGHLWRWIWQMNHSSEKQGGNSLSEKMAPLSDSEQDVKKKVKKLDHHIKKLYRSLQDNTLCVVLFPGTNSIHGSQSGLGMMGIKDDGGSSAC", "length": 773, "header": "tr|A0A8V0Z4K9-1|A0A8V0Z4K9_CHICK Isoform 1 of RNA exonuclease 5 OS=Gallus gallus OX=9031 GN=REXO5 PE=4 SV=1 CANONICAL=A0A8V0Z4K9-1" }, "locus": { "chromosome": "14", "start_pos": 15027330, "end_pos": 15012891, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043485.1", "url": "https://www.ensembl.org/id/ENSGALT00010043485.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025854.1", "url": "https://www.ensembl.org/id/ENSGALP00010025854.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:427001", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:427001", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A111-1", "protein_name": "RNA exonuclease 5", "gene_name": "REXO5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPERERTGRAPKRGKKRRRVANQLVGAAEAMRARWDLEERQQPEAKKARLSTILFAENCEITHGQLCELLKYAVLGKSSVPKPSWCQLFHQNHLNNVVVFILQGMSQLHFYRFYLEFGFLRKAFRHKFRLPPPSSDFLADIIGLQRKKKIGDLSKTMEGSLPSVSSKVSISPQNDPIIQKYGSKKVGLTRCLLTKEEMKAYHFPLQGFPDCENFVPTKCNGSITDNSPLFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPDNKIVDYLTSFSGITKKILNPVTTKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFLAKTILGKDIQCPDRLGHDAIEDARTTLELARYFLKYGPKKIAELNLETVASHQELQAAGQEPRNTAEVVQQLNAGVLECLDSLGQKLLFLTREADASELSSSKTCQTIKCLSNKEVLEQARVEIPLFPFSIVQFSFEPFSPNLTEEMNKRMLIKWTEMSTVYAGPFSKNCNLRALKKLFKSFGPVRSMTLVLETHQPHLCIQYEVLEAAQLAIESLDGILVEGACIKVQRPVTELTLDCDTLVNELEHDSENRGTIYLSGVRETFKEHLLQRSSLFLGLEAVILPKDLKSGKQKKYCFLRFKTFGRAQRALDILTGKDWKLKGRHALTPRHLQAWLRGLPLESRRPPGLRVIPPPSEQEALQMLKVDHPKIAAWRWGRKIGKLYHSLCPGTLCLILLPGTKRQKLSSLLICCSTHGSLSGLGLMGIKDEEESSTPNMCL", "length": 787 }, "evidence": [ { "id": "A0A8V0Z4K9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4K9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A1A5R7-1", "protein_name": "RNA exonuclease 5", "gene_name": "Rexo5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELEEEENPRKRKETPNSALTTELDRPSWDVQDPEPQAKKARLSTILFTDNCEVTHRQLCELLKYAILGKSTLPKPSWCQLLHQKQLNNVVVFILKGMSQLHFYRFYLEFRFLRKTFRHKFSLPPPTSSFLFDIIGLQKKKSARGCPRTVEGPLISATLKSSIDLQNDPIIQKYGYKNVSLTRCLLTKEEMKTFHFPLQGSPNCENFILLKYSGFITDSSPLFGLDCEVCLTSMGKELTRISLVAEGGYCLMDELVKPDFKILDYLTSFSGITKEILNPVTTKLKDVQKLLRELLPPDAVLVGHCLDLDLRVLKIIHPYVIDTSLLYIGKQGRRFKLTFLAKVILGKDIQCPNKLGHDGIEDARTALELVQYFLKYGPKKIAEFNLEALAANQEQGNKEGATHMRSVLECLDSMGQKLLFLTQDIDELSSYRNCQTVKCSSNKEVLEQARVEVPLFPFNIVQFSFRPFPPLFAEEMKNNMKTRWTEMSTIYAGPFSKDCNVGSLKKVFSSLGPVQSITLVLETYRPYFSIQYELLEAAQLAIETMNGTILEGSCIRVHRLLTELTLECDTLVRELEQDSENQGTIYVAGIGETFKEHLLEQSNLFPDLEAVILPKELKSRKQKNYCFLKFKTFNSAQVALEVLKGKDWKLKGRNALTSRHLQAWLKNIHPEPSMPMGLRIVPPLLERHIFRTLKANHPKIVAWRWSRRIEKLYHSLSPGTFCLILLPGTKNTFGSHPGLGLMKIKEEEGGDTLL", "length": 754 }, "evidence": [ { "id": "A0A8V0Z4K9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3YW29-1", "protein_name": "RNA exonuclease 5", "gene_name": "Rexo5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQEKEEANSRKRKEAPNSSASATERDGPPSHIQDREPQAKKARLSTILFTDNCEVTHRQLCELLKYAVLGKSAVPKPSWCQLSHQKQLNNVVVFILKGMSQLHFYRFYLEFRFLRKTFRHKFSLPSPTSSFLFDIIGLQKKKSARSFRRTVEGPLISATLRSSIDLQNDPIIQKYGYKNVGLTKCLLTKEEMKTFHFPLPGSPNYENFILTKYTGFITDSSPLFGLDCEVCLTSMGKELTRISLVTEGGYCLIDELVKPDLKILDYLTSFTGITKEILNPVTTKLKDVQKLLRELLPPDAVLVGHCLDLDLRVLKMIHPYVIDTSLLYAGKQGRRFKLTFLARVILGKDIQCPNKLGRDGIEDARAALELLQYFLKYGPKKIAEFNLEALAANQEQGDKEEAAHMRCVLKCLESMGQKLLFLTQDINELSSYRNCQTIKCSSNKKVLEQARVEVPLFPFNIVEFSFQPFPPLFAEEMKNSMKTKWTQMSTVYAGPFSKDCNVGALKKVFSSLGPVHSITLVLETYRPYFSIQYEVLEAAQLALETMNGSLLEGSCIRVRRLVTELTLECDTLVRELEQDSENQGTIYVAGIGETFKEHLLEQSNLFPDLEAVILPKEVKSRKQKNYCFLKFKTVNSAQVALEILKGKDWKLKGRNALTPRHLQAWLKDIHPEPAMPMGLRIVPPLMERHIFRTRKVNHPKIVAWRWSRKIEKLYHSLSPGTFCLILMPGTKNAFGSHPGLGLMKIKEEEESDTPGVRV", "length": 759 }, "evidence": [ { "id": "A0A8V0Z4K9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2T9U5-1", "protein_name": "RNA exonuclease 5", "gene_name": "REXO5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPERKRSGSTLKKGRKRRLIPSKVVGAAEATRSHWDLEEKQQPIAKKARLSTVLFAENCEVTHGQLCELLKYAVLGKSSFPKPSWCQLFHQNHLKNVVVFILQGLSQLHFYKFYLEFGFLRKAFKHKFRMPPPSSDFLADIIGLQKKQIIGNLPKAMEGSLPFASSKVSINLQKDPIIQKYGFKKVGLTRCLLTKEEMKTYHFPLQGFLDCENFVPTKCNGSVTDNSPLFGLDCEMCLTSKGRELTRISLVAEGGGCVMDELVKPDNKIVDYLTSFSGITKKILNPVTTKLKDVQRRLKILLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFLAKAILGKDIQCPDRLGHDATEDARTTLELARYFLKYGPKKIAELNLEALFSYQESQEPRNTAEGVQRLNTSVLECLDSVGQKLLFLTQEADASALSSSKNCQTIKCLSNKEVLEQARVEIPLFPFSIVQFSFEPFSPNLTQEMNKRIKIKWTEMSTVYAGPFNKNCNLSALKRLFKSFGPVQLMTLVLETHQPHLCIQYEVLEAAQLAIESLDGVLVEGSCIKVQRPVTELTLDCDTLVNELEQDSENRGTIYLSGVSETFKEHLLQHCSIFLGLEAMILPKDLKSGKQKGYCFLRFKTFGSAQRALNILTGKDWKLRGRHALTPRHLHAWLRGLARESRLPGVRVIPPPSEQEAWQMLNVDHPKIAAWHWGRKIEKLYHNLCPGTLCLILLPGTKSTHGSLSGLGLMGIKDEEESTIPQTCVCESAHHLPGVIS", "length": 783 }, "evidence": [ { "id": "A0A8V0Z4K9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96IC2-1", "protein_name": "RNA exonuclease 5", "gene_name": "REXO5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPEREGTERHPRKVRESRQAPNKLVGAAEAMKAGWDLEESQPEAKKARLSTILFTDNCEVTHDQLCELLKYAVLGKSNVPKPSWCQLFHQNHLNNVVVFVLQGMSQLHFYRFYLEFGCLRKAFRHKFRLPPPSSDFLADVVGLQTEQRAGDLPKTMEGPLPSNAKAAINLQDDPIIQKYGSKKVGLTRCLLTKEEMRTFHFPLQGFPDCENFLLTKCNGSIADNSPLFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVTTKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFKLKFLAKVILGKDIQCPDRLGHDATEDARTILELARYFLKHGPKKIAELNLEALANHQEIQAAGQEPKNTAEVLQHPNTSVLECLDSVGQKLLFLTRETDAGELPSSRNCQTIKCLSNKEVLEQARVEIPLFPFSIVQFSFKAFSPVLTEEMNKRMRIKWTEISTVYAGPFSKNCNLRALKRLFKSFGPVQSMTFVLETRQPHLCIQYEVLEAAQLAIESLDGILVDGICIKVQRPVTELTLDCDTLVNELEGDSENQGSIYLSGVSETFKEQLLQEPRLFLGLEAVILPKDLKSGKQKKYCFLKFKSFGSAQQALNILTGKDWKLKGRHALTPRHLHAWLRGLPPESTRLPGLRVVPPPFEQEALQTLKLDHPKIAAWRWSRKIGKLYNSLCPGTLCLILLPGTKSTHGSLSGLGLMGIKEEEESAGPGLCS", "length": 774 }, "evidence": [ { "id": "A0A8V0Z4K9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9" } ], "pmid": "" }, { "name": "exonuclease activity", "id": "GO:0004527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004527", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA 3'-end processing", "id": "GO:0031125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031125", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4K9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K9" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 508, "end_pos": 582, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 417, "end_pos": 419 }, { "start_pos": 693, "end_pos": 695 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4L1-1", "uniprot_ac": "A0A8V0Z4L1", "uniprot_id": "A0A8V0Z4L1_CHICK", "mass": { "chemical_mass": 67573.0, "monoisotopic_mass": 67573.0 }, "refseq": { "ac": "XP_015152854", "name": "set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152854" }, "gene_names": [ { "name": "ASH2L", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ] }, { "name": "ASH2L", "type": "synonym", "evidence": [ { "id": "XP_015152854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152854" } ] } ], "protein_names": [ { "name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1/entry#names_and_taxonomy" } ] }, { "name": "ASH2-like protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1/entry#names_and_taxonomy" } ] }, { "name": "set1/Ash2 histone methyltransferase complex subunit ASH2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_015152854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152854" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052553.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015152854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152854" } ] }, { "annotation": "Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K7#function" }, { "database": "UniProtKB", "id": "ARBA00056054", "url": "https://www.uniprot.org/uniprotkb/ARBA00056054#function" }, { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ASH2L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1", "locus": { "chromosome": "22", "start_pos": 2437179, "end_pos": 2429653, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017774", "url": "https://www.ensembl.org/id/ENSGALG00010017774" } ] } } ], "crossref": [ { "id": "A0A8V0Z4L1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4L1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12872", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12872", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15583", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15583", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "426774", "url": "https://www.ncbi.nlm.nih.gov/gene/426774", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CATCSRW", "url": "https://omabrowser.org/oma/group/CATCSRW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4K7", "url": "https://www.orthodb.org/?gene=A0A8V0Z4K7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4L1", "url": "https://www.orthodb.org/?gene=A0A8V0Z4L1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10598", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10598", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10598:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10598:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21198", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21198", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-8936459", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8936459", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9772755", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9772755", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9909649", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9909649", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_015152854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015152854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4K7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4K7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAAAAAAMAAPAGESAEAAPEPPAAEPPAPPEPSAADAESGGEAAPGDAAAAAVETETASGKDPMEAAPDGPEAMDTQAGSVDEENGRQLGEIELQCGICTKWFTADTFGIDTTSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMCKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLANIGPAYDNQKQNNAVSTSGNLNDGASLGGGIAAGGSGKGRGAKRKQQDGSTTGTAKKTRSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEISMDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYISLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQAPGSQIIFFKNGASQGVAFKDIFEGVYFPAISLYKGCTVSINFGPYFKYPPRDITYRPMSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP", "length": 617, "header": "tr|A0A8V0Z4L1-1|A0A8V0Z4L1_CHICK Isoform 1 of Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Gallus gallus OX=9031 GN=ASH2L PE=1 SV=1 CANONICAL=A0A8V0Z4L1-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1/entry#A0A8V0Z4K7-1", "sequence": { "sequence": "MAAPAGESAEAAPEPPAAEPPAPPEPSAADAESGGEAAPGDAAAAAVETETASGKDPMEAAPDGPEAMDTQAGSVDEENGRQLGEIELQCGICTKWFTADTFGIDTTSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMCKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLANIGPAYDNQKQNNAVSTSGNLNGGIAAGGSGKGRGAKRKQQDGSTTGTAKKTRSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEISMDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYISLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQAPGSQIIFFKNGASQGVAFKDIFEGVYFPAISLYKGCTVFVQGAQECKRVRAEDWGEKKRAEFSSFGLTNVLCRFLSTSGRISSIPPEISRTAP", "length": 602, "header": "tr|A0A8V0Z4K7-1|A0A8V0Z4L1_CHICK Computationally mapped isoform of Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Gallus gallus OX=9031 GN=ASH2L PE=1 SV=1 CANONICAL=A0A8V0Z4L1-1" }, "locus": { "chromosome": "22", "start_pos": 2436490, "end_pos": 2429815, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042955.1", "url": "https://www.ensembl.org/id/ENSGALT00010042955.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025445.1", "url": "https://www.ensembl.org/id/ENSGALP00010025445.1" } ] } }, { "isoform_ac": "A0A8V0Z4L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1/entry#A0A8V0Z4L1-1", "sequence": { "sequence": "MAAAAAAAAAMAAPAGESAEAAPEPPAAEPPAPPEPSAADAESGGEAAPGDAAAAAVETETASGKDPMEAAPDGPEAMDTQAGSVDEENGRQLGEIELQCGICTKWFTADTFGIDTTSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMCKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLANIGPAYDNQKQNNAVSTSGNLNDGASLGGGIAAGGSGKGRGAKRKQQDGSTTGTAKKTRSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEISMDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYISLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQAPGSQIIFFKNGASQGVAFKDIFEGVYFPAISLYKGCTVSINFGPYFKYPPRDITYRPMSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP", "length": 617, "header": "tr|A0A8V0Z4L1-1|A0A8V0Z4L1_CHICK Isoform 1 of Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Gallus gallus OX=9031 GN=ASH2L PE=1 SV=1 CANONICAL=A0A8V0Z4L1-1" }, "locus": { "chromosome": "22", "start_pos": 2436594, "end_pos": 2429785, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042960.1", "url": "https://www.ensembl.org/id/ENSGALT00010042960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025450.1", "url": "https://www.ensembl.org/id/ENSGALP00010025450.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-8936459", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-8936459", "resource": "Reactome", "description": "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" }, { "id": "R-GGA-9772755", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9772755", "resource": "Reactome", "description": "Formation of WDR5-containing histone-modifying complexes" }, { "id": "R-GGA-9909649", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9909649", "resource": "Reactome", "description": "Regulation of PD-L1(CD274) transcription" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JT90-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "Ash2l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAATGVGPGPGVGAGSGPGAAASATTTEDRETEPATAGAGEGPSAAPGAEPSSGEAESGDANLVDVSGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSASGNLNGGATLGGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPSFKYPPKDVTYHPMSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP", "length": 629 }, "evidence": [ { "id": "A0A8V0Z4L1", "url": "https://omabrowser.org/oma/group/A0A8V0Z4L1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RAW8-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ash2l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAEARSVTERDTADGDASFGDLTTNMETESSSGKETMDTAGDSSEAADAQTGSGDDENGRQLGEVELQCALCMKWFTADTFSIDTATCLPFMTNYVFHCNVCHHSGNTYFLRKQANLKEMCLTALANLTWRSRTQEEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKLTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLGNIGPSYDNQKQMTTVTGAGGLNGGSTFSGGLPSAATGKGRGAKRKQQQQQDGAATGAAKRTRSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVTGEKGYSMVRASHGVRKGSWFFEVTVDEMPQDAAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTRFHQSIGKHYSDGYGLGDILGFFIELPDETETAKALPDTYKDKALIKFKSYLYFEEKDYVDKAEKNLKPTSTSRMIFFKNGVNQGVAYEDLFEGMYYPAISLYKGCTVSVNFGPHFKYPPKDIKFQPMSDMGWGAVIEHTLADMLYHVETEVDGRRSPQYEG", "length": 590 }, "evidence": [ { "id": "A0A8V0Z4L1", "url": "https://omabrowser.org/oma/group/A0A8V0Z4L1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q91X20-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "Ash2l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGAGPGPGVSAGPGPGAAASATTAEDRETEPVAAGAGEGPSAAPGAEPSSGEAESGDANLVDVSGLETESSNGKDTLEGTGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSASGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYRDIFEGVYFPAISLYKSCTVSINFGPSFKYPPKDLTYHPMSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP", "length": 623 }, "evidence": [ { "id": "A0A8V0Z4L1", "url": "https://omabrowser.org/oma/group/A0A8V0Z4L1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94545-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ash2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEDSQMDTSSPTESSSEVNFTAEEDKSQETRSAAGVCYCGKERNLNIVELLCATCSRWVHETCVSYQLGKGKLLPFITNYVFVCKNCSASGLESFRKSQATISQMCHCAIANMQQAASRDGRRQIQFSKDKEIIPYIEQYWEAMTTMPRRLTQSWYSTVQRSLVKDVQTLFTYEEHAEHGAMYGLFHQDLRIIKPNYESMSKSGALRLTDDGYTQASLSKNNRQKRKFPGTDSGPTGKKGRPSSDITANVKLPPHGYPLEHPFNKDGYRYILAEPDPHAPFRQEFDESSDWAGKPIPGWLYRILVPHSVLLALHDRAPQLKISEDRLAVTGERGYCMVRATHSVNRGCWYFEVTIEEMPDGAATRLGWGREYGNLQAPLGYDKFGYSWRSRKGTKFTESHGKHYSDAYVEGDTLGFLIELPEEASLDYLPNTFKDRPLVKFKSHLYYEDKDKITETLKNLHILQGSRIEFFKNGQSQGVAFEDIYAGSYFPAISIHKSATVSVNFGPAFKYPEVLVEHKAKGMHDRVEELITEQCLADTLYLTEHDGRLRLDNMGL", "length": 556 }, "evidence": [ { "id": "A0A8V0Z4L1", "url": "https://omabrowser.org/oma/group/A0A8V0Z4L1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKSCTVSINFGPCFKYPPKDLTYRPMSDMGWGAVVEHTLADVLYHVETEVDGRRSPPWEP", "length": 628 }, "evidence": [ { "id": "A0A8V0Z4L1", "url": "https://omabrowser.org/oma/group/A0A8V0Z4L1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of macromolecule biosynthetic process", "id": "GO:0010557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010557", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "response to estrogen", "id": "GO:0043627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043627", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "MLL1 complex", "id": "GO:0071339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071339", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" }, { "name": "MLL3/4 complex", "id": "GO:0044666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044666", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4L1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4L1" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 349, "end_pos": 572, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], 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"protein_names": [ { "name": "Large ribosomal subunit protein uL29m", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N6/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L47, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_422785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422785" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052540.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_422785.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_422785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422785" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MRPL47", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N6", "locus": { "chromosome": "9", "start_pos": 17137484, "end_pos": 17133633, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018143", "url": "https://www.ensembl.org/id/ENSGALG00010018143" } ] } } ], "crossref": [ { "id": "A0A8V0Z4N6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4N6", "database": "AlphaFoldDB", "categories": [] }, { "id": "424977", "url": 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{ "id": "PTHR21183:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21183:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_422785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_422785", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4N6", "url": 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"MAAARAIAALGRRLAGALRLSGARPGLVAAGLPGLTLNPCHRNLAQAEPLCHARFLHATLPRKGLEEFFDDPKNWGEKTVKSGDAWNIKQLRAKSSQDLHKLWYVLLKEKNMLLTLEQESKRQQKPMPSPERLEKVQKSMKNIDLVVREREIALRLLQTGHEKPVPGEWRNDFLGRTYWYSYKEWPIPWYLNKKYQKRKFYYLPHVNRFIRLRLEKKLRLRNRRQNLEKKKRKLLEKKFPHLAVKSQSQ", "length": 249, "header": "tr|A0A8V0Z4N6-1|A0A8V0Z4N6_CHICK Isoform 1 of Large ribosomal subunit protein uL29m OS=Gallus gallus OX=9031 GN=MRPL47 PE=1 SV=1 CANONICAL=A0A8V0Z4N6-1" }, "locus": { "chromosome": "9", "start_pos": 17136606, "end_pos": 17133649, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043842.1", "url": "https://www.ensembl.org/id/ENSGALT00010043842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026075.1", "url": "https://www.ensembl.org/id/ENSGALP00010026075.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:424977", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424977", 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"database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F7EW23-1", "protein_name": "Large ribosomal subunit protein uL29m", "gene_name": "Mrpl47", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAATSLVGICRRASAFLKAACSLVNPKTPAHSGCRPPLSLLHKNTPHATSFLQCKFLHTTLSRKGLEEFFDDPKNWGEEKVKSGASWTCQQLRNKSNEDLHKLWYVLLKERNMLLTLEQEAKRQRLPMPSPERLEKVVDSMDALDKVVQEREDALRLLQTGQEKPRPGAWRQDIFGRIVWHKFKQWPIPWYLNKRYNRRRFFAMPYVDSFIRLRIEKHARTEARKRSLQKKKEKILQAKFPHLSQDRKSKLGTEPRALCLLGKSSTTELNPKPQIE", "length": 276 }, "evidence": [ { "id": "A0A8V0Z4N6", "url": "https://omabrowser.org/oma/group/A0A8V0Z4N6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K2Y7-1", "protein_name": "Large ribosomal subunit protein uL29m", "gene_name": "Mrpl47", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4N6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4N6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial translation", "id": "GO:0032543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4N6", "url": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" } ] } ], "protein_names": [ { "name": "Kainate binding protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "KBP", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4", "locus": { "chromosome": "21", "start_pos": 1447940, "end_pos": 1458991, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019744", "url": "https://www.ensembl.org/id/ENSGALG00010019744" } ] } } ], "crossref": [ { "id": "A0A8V0Z4P4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4P4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13685", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13685", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4P4", "url": "https://www.orthodb.org/?gene=A0A8V0Z4P4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00060", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00060", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10613", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10613", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKGLHFIFCVVTAVLLLRESSQTGAMRNDDAMIKPNDLRGPEENLPSLTVTTILEDPYVMVRSAELEGYCIDLLKALASMLHFSYKVKVVGDGKYGAISPSGNWTGMIGEILRQEADIAVAPLTVTSAREEEMSFFHFLAPFSKETWTGLLFAYVLTCVCLFLVARLSPCEWNEPKNEENHFTFLNSLWFGAGALTLQGVTPRPKAFSVRVIAAIWWLFTIALLAAYIANFTALLSSGSEQLSIQTFEDLVKQRKLEFGTLDGSSTFYFFKNSKNPIHRMVYEYMDKRRDHVLVKTYQEAVQRVMESNYAFIGESISQDLAAARHCNLIRAPEVIGARGFGIATAQASPWTKKLSVAVLKLRETGDLDYLRNKWWESSCLHKSREGWSPLQPQALGGLFLTLAIGLALGVIAAMVELSNKSRHAAGHIKKSCCSIFTEEMCTRLRIKENTRQTQETSGRANA", "length": 463, "header": "tr|A0A8V0Z4P4-1|A0A8V0Z4P4_CHICK Isoform 1 of Kainate binding protein OS=Gallus gallus OX=9031 GN=KBP PE=4 SV=1 CANONICAL=A0A8V0Z4P4-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4/entry#A0A8V0Z4P4-1", "sequence": { "sequence": "MDKGLHFIFCVVTAVLLLRESSQTGAMRNDDAMIKPNDLRGPEENLPSLTVTTILEDPYVMVRSAELEGYCIDLLKALASMLHFSYKVKVVGDGKYGAISPSGNWTGMIGEILRQEADIAVAPLTVTSAREEEMSFFHFLAPFSKETWTGLLFAYVLTCVCLFLVARLSPCEWNEPKNEENHFTFLNSLWFGAGALTLQGVTPRPKAFSVRVIAAIWWLFTIALLAAYIANFTALLSSGSEQLSIQTFEDLVKQRKLEFGTLDGSSTFYFFKNSKNPIHRMVYEYMDKRRDHVLVKTYQEAVQRVMESNYAFIGESISQDLAAARHCNLIRAPEVIGARGFGIATAQASPWTKKLSVAVLKLRETGDLDYLRNKWWESSCLHKSREGWSPLQPQALGGLFLTLAIGLALGVIAAMVELSNKSRHAAGHIKKSCCSIFTEEMCTRLRIKENTRQTQETSGRANA", "length": 463, "header": "tr|A0A8V0Z4P4-1|A0A8V0Z4P4_CHICK Isoform 1 of Kainate binding protein OS=Gallus gallus OX=9031 GN=KBP PE=4 SV=1 CANONICAL=A0A8V0Z4P4-1" }, "locus": { "chromosome": "21", "start_pos": 1457749, "end_pos": 1449748, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047668.1", "url": "https://www.ensembl.org/id/ENSGALT00010047668.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028209.1", "url": "https://www.ensembl.org/id/ENSGALP00010028209.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" } ], "pmid": "" }, { "name": "AMPA glutamate receptor complex", "id": "GO:0032281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032281", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" } ], "pmid": "" }, { "name": "postsynaptic density membrane", "id": "GO:0098839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098839", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "synaptic transmission, glutamatergic", "id": "GO:0035249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035249", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" } ], "pmid": "" }, { "name": "modulation of chemical synaptic transmission", "id": "GO:0050804", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050804", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "id": "GO:1904315", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904315", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" } ], "pmid": "" }, { "name": "AMPA glutamate receptor activity", "id": "GO:0004971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004971", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" }, { "id": "SM00079", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00079" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ionotropic glutamate receptor C-terminal", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 378, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P4" }, { "id": "SM00918", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00918" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ionotropic glutamate receptor L-glutamate and glycine-binding", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 114, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 420, "end_pos": 422 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4P6-1", "uniprot_ac": "A0A8V0Z4P6", "uniprot_id": "A0A8V0Z4P6_CHICK", "mass": { "chemical_mass": 29782.0, "monoisotopic_mass": 29782.0 }, "refseq": {}, "gene_names": [ { "name": "MXI1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ] } ], "protein_names": [ { "name": "MAX interactor 1, dimerization protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MXI1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6", "locus": { "chromosome": "6", "start_pos": 26659824, "end_pos": 26607899, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017796", "url": "https://www.ensembl.org/id/ENSGALG00010017796" } ] } } ], "crossref": [ { "id": "A0A8V0Z4P6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4P6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000008555", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000008555", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18930", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18930", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423888", "url": "https://www.ncbi.nlm.nih.gov/gene/423888", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:423888", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423888", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ECTRHTT", "url": "https://omabrowser.org/oma/group/ECTRHTT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4P6", "url": "https://www.orthodb.org/?gene=A0A8V0Z4P6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAJ1", "url": "https://www.orthodb.org/?gene=A0A8V0ZAJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1NYY8", "url": "https://www.orthodb.org/?gene=F1NYY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11969:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11969:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NYY8", "url": "https://www.uniprot.org/uniprotkb/F1NYY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1NYY8-1", "url": "https://www.uniprot.org/uniprotkb/F1NYY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "WRRGRSSALRLRERRCFGGHCETAGCFSVFFSSSSSSLCPKGKCRNHVAGGGIANRIVLPLACNECEHGYASTFPSAPSPGLQDPKPTRRLSRARKHSGSGSSASIANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEVERRSQHQLENLEREQRFLKRRLEQLQGPQEIERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLQSIGSDEGYSSASVKLSFAS", "length": 268, "header": "tr|A0A8V0Z4P6-1|A0A8V0Z4P6_CHICK Isoform 1 of MAX interactor 1, dimerization protein OS=Gallus gallus OX=9031 GN=MXI1 PE=4 SV=1 CANONICAL=A0A8V0Z4P6-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6/entry#A0A8V0Z4P6-1", "sequence": { "sequence": "WRRGRSSALRLRERRCFGGHCETAGCFSVFFSSSSSSLCPKGKCRNHVAGGGIANRIVLPLACNECEHGYASTFPSAPSPGLQDPKPTRRLSRARKHSGSGSSASIANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEVERRSQHQLENLEREQRFLKRRLEQLQGPQEIERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLQSIGSDEGYSSASVKLSFAS", "length": 268, "header": "tr|A0A8V0Z4P6-1|A0A8V0Z4P6_CHICK Isoform 1 of MAX interactor 1, dimerization protein OS=Gallus gallus OX=9031 GN=MXI1 PE=4 SV=1 CANONICAL=A0A8V0Z4P6-1" }, "locus": { "chromosome": "6", "start_pos": 26658098, "end_pos": 26609454, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043000.1", "url": "https://www.ensembl.org/id/ENSGALT00010043000.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025490.1", "url": "https://www.ensembl.org/id/ENSGALP00010025490.1" } ] } }, { "isoform_ac": "A0A8V0ZAJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6/entry#A0A8V0ZAJ1-1", "sequence": { "sequence": "MERVQLINIQRLLEAAEYLERRERECEHGYASTFPSAPSPGLQDPKPTRRLSRARKHSGSGSSASIANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEVERRSQHQLENLEREQRFLKRRLEQLQGPQEIERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLQSIGSDEGYSSASVKLSFAS", "length": 228, "header": "tr|A0A8V0ZAJ1-1|A0A8V0Z4P6_CHICK Computationally mapped isoform of MAX interactor 1, dimerization protein OS=Gallus gallus OX=9031 GN=MXI1 PE=4 SV=1 CANONICAL=A0A8V0Z4P6-1" }, "locus": { "chromosome": "6", "start_pos": 26658098, "end_pos": 26616123, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010042998.1", "url": "https://www.ensembl.org/id/ENSGALT00010042998.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025488.1", "url": "https://www.ensembl.org/id/ENSGALP00010025488.1" } ] } }, { "isoform_ac": "F1NYY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6/entry#F1NYY8-1", "sequence": { "sequence": "MGKRGRPRREPRGAAGEAGGARCPLGDIFNTGPGMDTFLHNVQVLLEAASYLERIEKENKKCEHGYASTFPSAPSPGLQDPKPTRRLSRARKHSGSGSSASIANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEVERRSQHQLENLEREQRFLKRRLEQLQGPQEIERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLQSIGSDEGYSSASVKLSFAS", "length": 264, "header": "tr|F1NYY8-1|A0A8V0Z4P6_CHICK Computationally mapped isoform of MAX interactor 1, dimerization protein OS=Gallus gallus OX=9031 GN=MXI1 PE=4 SV=2 CANONICAL=A0A8V0Z4P6-1" }, "locus": { "chromosome": "6", "start_pos": 26658098, "end_pos": 26608028, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043005.1", "url": "https://www.ensembl.org/id/ENSGALT00010043005.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025495.1", "url": "https://www.ensembl.org/id/ENSGALP00010025495.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:423888", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:423888", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LDS9-1", "protein_name": "MAX interactor 1, dimerization protein", "gene_name": "MXI1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERVRMINVQRLLEAAEFLERRDRECEHGYASTFPSMPSPRMQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLQSIGSDEGYSSASVKLSFTS", "length": 228 }, "evidence": [ { "id": "A0A8V0Z4P6", "url": "https://omabrowser.org/oma/group/A0A8V0Z4P6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O09015-1", "protein_name": "Max-interacting protein 1", "gene_name": "Mxi1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERVKMINVQPMLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLQSIGSDEGYSSASVKLSFTS", "length": 228 }, "evidence": [ { "id": "A0A8V0Z4P6", "url": "https://omabrowser.org/oma/group/A0A8V0Z4P6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P50539-1", "protein_name": "Max-interacting protein 1", "gene_name": "MXI1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERVKMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS", "length": 228 }, "evidence": [ { "id": "A0A8V0Z4P6", "url": "https://omabrowser.org/oma/group/A0A8V0Z4P6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50540-1", "protein_name": "Max-interacting protein 1", "gene_name": "Mxi1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERVRMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEADSVSTTSISDLDDHSSLQSVGSDEGYSSASVKLSFAS", "length": 228 }, "evidence": [ { "id": "A0A8V0Z4P6", "url": "https://omabrowser.org/oma/group/A0A8V0Z4P6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P50541-1", "protein_name": "Max-interacting protein 1", "gene_name": "mxi1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTCPFNDVFNSTDSSMINTFLKNVQVLLEAASYIESAERKDGKCEHGYASTFPSIQHSSYQRQRKFRNKKCNNNHYRSTHNELEKNRRAHLRLCLERLKTLIPLGPECSRHTTLGLLNKAKAHIKKLEEADRKSRYQLESLEREQRHLRRRLDLLRDGGGSLEAERIRTDSMGSTPCSERSDRSDSDQEEMEVDVESTEFSHGELDSVSTASTSDLDDHSSLQSTASDEGYSSCSIKLAFSS", "length": 243 }, "evidence": [ { "id": "A0A8V0Z4P6", "url": "https://omabrowser.org/oma/group/A0A8V0Z4P6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4P6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4P6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4P6" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 107, "end_pos": 159, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 233, "end_pos": 235 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4U5-1", "uniprot_ac": "A0A8V0Z4U5", "uniprot_id": "A0A8V0Z4U5_CHICK", "mass": { "chemical_mass": 122174.0, "monoisotopic_mass": 122174.0 }, "refseq": { "ac": "XP_040528867", "name": "mis18-binding protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528867" }, "gene_names": [ { "name": "MIS18BP1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4U5" } ] }, { "name": "MIS18BP1", "type": "synonym", "evidence": [ { "id": "XP_040528867", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528867" } ] } ], "protein_names": [ { "name": "Mis18-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4U5/entry#names_and_taxonomy" } ] }, { "name": "Kinetochore-associated protein KNL-2 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4U5/entry#names_and_taxonomy" } ] }, { "name": "mis18-binding protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_040528867", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528867" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052577.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040528867", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528867" } ] }, { "annotation": "Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4U5#function" }, { "database": "UniProtKB", "id": "ARBA00003694", "url": "https://www.uniprot.org/uniprotkb/ARBA00003694#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4U5" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "MIS18BP1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4U5", "locus": { "chromosome": "5", "start_pos": 58496933, "end_pos": 58479274, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018189", "url": "https://www.ensembl.org/id/ENSGALG00010018189" } ] } } ], "crossref": [ { "id": "A0A8V0Z4U5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4U5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "423593", "url": "https://www.ncbi.nlm.nih.gov/gene/423593", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4U5", "url": "https://www.orthodb.org/?gene=A0A8V0Z4U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16124", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16124", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16124:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16124:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-606279", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-606279", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-69273", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-69273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040528867", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040528867", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4U5", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4U5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIATPRRGEMPFQAVFLSSIPAGTLTPLKDLRCRGNSALCPPARPAPGPVLQSTLLEGGAGAREPLEISEIRPGPGPPPPKRRAREPPAQQSPAAAFLRMKMKTRAGGGSDRILTPGGPGPRVAGGGQRRAAEPPRRELPCIRIPQNQAVKMLNVDPIVLESPQKFFLRVKQKLQQKQQQKDPTFSSPNKQNIRPPPAAEKPVVKSAFGELLPNAQTEHVATNKDNEDNFLVESMDADDEMSLNTVTSTVGFHSTPPDPGDQLERRCGNREAKRTELQQEKRRLQPGDQRAEHRAEKILETATQKPSQHFCNVVLSTPEACMPRKEKQKENCNGPLDKPQADQIAVAAEKEKRICLSSWRIKVMNGNTAICVEGKRKDMKDMLWHSNAVVERVAHNQVKTSSGNIYLLQGNIDSVSMRKEGFSYQFTKRFTSGFSKRWKEYVEEFLRGLRRKERKKKMGEDENEERDSVVDTDKVQSAEDSARNVRKRETRNTTYEVLSRKDEHTYQTPKHKPILNSSNGIYTRSGRLVKPPLSFWCGEREFVDRELNVTIQKGGTDYLSMMYSTENPKRKTSSLSKLKERKDSTKTVEEKTKGQDKGNSEEKRIKTKNKATSTGSREARCFISDDENDHASDINKIKVWLSNKETHLNTGDRNKRDYNSRNMGTRKEKTGKEYGEMATGQNMYSLRSAKKPFQGKPLTEEFSSKDGEEESSDYIQLTVKRKNKPFLPKEIQNSESSSTCERLQGSTSEVSSGLQADTRCTAASHTMQLRQRIPAFIESSDSSEGETSSGEEYHAKEKRSEVSNKKAKRDVCNTTKPSTGKPSESKGDKVHKTLDFFSKAADDWSQKELQKLHRAVASFPKHKNGFWVDVAMAVGSRSAEDCHWKYTEEQAKASKRPAVKKTTSGKPEQKDKAEPVAITAKVGTFKRKQQMRDFLDNLPKDDHDDVFTATPFQNRRVRLPTFLGSHDEEEDDDDDFALTNNPITPSSAVFPLAKTPQCEHISPGMLGPINRKDCDRHVFRMQKTQGCRSSWDNVKKQQAAALHGTPASSRTKSTFGKKVQQNPAVGKLFVAEAADTSEEEQEDSYFSV", "length": 1088, "header": "tr|A0A8V0Z4U5-1|A0A8V0Z4U5_CHICK Isoform 1 of Mis18-binding protein 1 OS=Gallus gallus OX=9031 GN=MIS18BP1 PE=4 SV=1 CANONICAL=A0A8V0Z4U5-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4U5/entry#A0A8V0Z4U5-1", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z4W8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZFAND6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8", "locus": { "chromosome": "10", "start_pos": 12593889, "end_pos": 12643338, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019810", "url": "https://www.ensembl.org/id/ENSGALG00010019810" } ] } } ], "crossref": [ { "id": "A0A8V0Z4W8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z4W8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSGALG00000006505", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000006505", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "415483", "url": "https://www.ncbi.nlm.nih.gov/gene/415483", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415483", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415483", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { 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"categories": [ "Protein Classification" ] }, { "id": "PF01428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9033241", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z4W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC69", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZC69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZC69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI71", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZI71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZI71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYN2", "url": "https://www.uniprot.org/uniprotkb/E1BYN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E1BYN2-1", "url": "https://www.uniprot.org/uniprotkb/E1BYN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLALILVEPRCVEEEKMAQETNRSQVPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSNGRISPPATSVSSITESLPVQCTEGSAQETQSTLDSSSTQSMQPSPVSSQSLLTESVASSQPDSTAVDKTVPETEELQASVSENAEPTPEEQDKSLDKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGMHRYSDVHSCSYNYKADAAEKIRKENPVVVGEKIQKI", "length": 225, "header": "tr|A0A8V0Z4W8-1|A0A8V0Z4W8_CHICK Isoform 1 of AN1-type zinc finger protein 6 OS=Gallus gallus OX=9031 GN=ZFAND6 PE=4 SV=1 CANONICAL=A0A8V0Z4W8-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8/entry#A0A8V0Z4W8-1", "sequence": { "sequence": "MRLALILVEPRCVEEEKMAQETNRSQVPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSNGRISPPATSVSSITESLPVQCTEGSAQETQSTLDSSSTQSMQPSPVSSQSLLTESVASSQPDSTAVDKTVPETEELQASVSENAEPTPEEQDKSLDKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGMHRYSDVHSCSYNYKADAAEKIRKENPVVVGEKIQKI", "length": 225, "header": "tr|A0A8V0Z4W8-1|A0A8V0Z4W8_CHICK Isoform 1 of AN1-type zinc finger protein 6 OS=Gallus gallus OX=9031 GN=ZFAND6 PE=4 SV=1 CANONICAL=A0A8V0Z4W8-1" }, "locus": { "chromosome": "10", "start_pos": 12620589, "end_pos": 12594683, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047833.1", "url": "https://www.ensembl.org/id/ENSGALT00010047833.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028279.1", "url": "https://www.ensembl.org/id/ENSGALP00010028279.1" } ] } }, { "isoform_ac": "A0A8V0ZC69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8/entry#A0A8V0ZC69-1", "sequence": { "sequence": "MLCWCVEEEKMAQETNRSQVPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSNGRISPPATSVSSITESLPVQCTEGSAQETQSTLDSSSTQSMQPSPVSSQSLLTESVASSQPDSTAVDKTVPETEELQASVSENAEPTPEEQDKSLDKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGMHRYSDVHSCSYNYKADAAEKIRKENPVVVGEKIQKI", "length": 218, "header": "tr|A0A8V0ZC69-1|A0A8V0Z4W8_CHICK Computationally mapped isoform of AN1-type zinc finger protein 6 OS=Gallus gallus OX=9031 GN=ZFAND6 PE=4 SV=1 CANONICAL=A0A8V0Z4W8-1" }, "locus": { "chromosome": "10", "start_pos": 12623289, "end_pos": 12594683, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047842.1", "url": "https://www.ensembl.org/id/ENSGALT00010047842.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028282.1", "url": "https://www.ensembl.org/id/ENSGALP00010028282.1" } ] } }, { "isoform_ac": "A0A8V0ZI71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8/entry#A0A8V0ZI71-1", "sequence": { "sequence": "MAQETNRSQVPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSNGRISPPATSVSSITESLPVQCTEGSAQETQSTLDSSSTQSMQPSPVSSQSLLTESVASSQPDSTAVDKTVPETEELQASVSENAEPTPEEQDKSLDKPKQKKNRCFMCRKKVGLTAELLLG", "length": 165, "header": "tr|A0A8V0ZI71-1|A0A8V0Z4W8_CHICK Computationally mapped isoform of AN1-type zinc finger protein 6 OS=Gallus gallus OX=9031 GN=ZFAND6 PE=4 SV=1 CANONICAL=A0A8V0Z4W8-1" }, "locus": { "chromosome": "10", "start_pos": 12605346, "end_pos": 12594941, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047863.1", "url": "https://www.ensembl.org/id/ENSGALT00010047863.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028290.1", "url": "https://www.ensembl.org/id/ENSGALP00010028290.1" } ] } }, { "isoform_ac": "E1BYN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8/entry#E1BYN2-1", "sequence": { "sequence": "MAQETNRSQVPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSNGRISPPATSVSSITESLPVQCTEGSAQETQSTLDSSSTQSMQPSPVSSQSLLTESVASSQPDSTAVDKTVPETEELQASVSENAEPTPEEQDKSLDKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGMHRYSDVHSCSYNYKADAAEKIRKENPVVVGEKIQKI", "length": 208, "header": "tr|E1BYN2-1|A0A8V0Z4W8_CHICK Computationally mapped isoform of AN1-type zinc finger protein 6 OS=Gallus gallus OX=9031 GN=ZFAND6 PE=4 SV=3 CANONICAL=A0A8V0Z4W8-1" }, "locus": { "chromosome": "10", "start_pos": 12605346, "end_pos": 12594683, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047855.1", "url": "https://www.ensembl.org/id/ENSGALT00010047855.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028287.1", "url": "https://www.ensembl.org/id/ENSGALP00010028287.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 148, "start_aa": "Thr", "end_pos": 148, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr148", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:415483", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415483", "resource": "KEGG Pathway" }, { "id": "R-GGA-9033241", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9033241", "resource": "Reactome", "description": "Peroxisomal protein import" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1USH9-1", "protein_name": "AN1-type zinc finger protein 6", "gene_name": "ZFAND6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQETNHSQVPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPAPSVSSLSESLPVQCTDGSVPEAQSTLDSTSSSLQPSPVPNQSLLSESVASSQVDSTSVDKAIPETEDLQASVSDTAQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVGEKIQKI", "length": 208 }, "evidence": [ { "id": "A0A8V0Z4W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z4W8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IHH7-1", "protein_name": "AN1-type zinc finger protein 6", "gene_name": "Zfand6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAQETNHSQAPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSSGRISPPAASVSSLSESLPVQCTDGSVAGAQSALESTSSSLQPGPVSNQSLLSESVAPSQVDSTSVDKAVSETEDLQGPRAEGLVPLECDPPSSVSDTTQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVGEKIQKI", "length": 223 }, "evidence": [ { "id": "A0A8V0Z4W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z4W8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3SZY7-1", "protein_name": "AN1-type zinc finger protein 6", "gene_name": "ZFAND6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAQETNHSQVPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPAPSVTSLSESLPVQCTDGSVPEAQSALDSTASSVQPSPVSNQSLLSESVASSQVDSTSVDKAIPETEDLQASVSETAQQASEEQSKSLEKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVGEKIQKI", "length": 208 }, "evidence": [ { "id": "A0A8V0Z4W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z4W8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6DGF4-1", "protein_name": "AN1-type zinc finger protein 6", "gene_name": "Zfand6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQETNHSQAPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPAASVSSLSESLPVQCADGSVPDAQSALDSTSSSMQPGPVSNQSLLSESVAPSQVDSTSVDKAVSETEDLQGPRAEGLVPLECDPPSSVSDTTQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVGEKIQKI", "length": 223 }, "evidence": [ { "id": "A0A8V0Z4W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z4W8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6FIF0-1", "protein_name": "AN1-type zinc finger protein 6", "gene_name": "ZFAND6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQETNHSQVPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPATSVSSLSESLPVQCTDGSVPEAQSALDSTSSSMQPSPVSNQSLLSESVASSQLDSTSVDKAVPETEDVQASVSDTAQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVGEKIQKI", "length": 208 }, "evidence": [ { "id": "A0A8V0Z4W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z4W8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DCH6-1", "protein_name": "AN1-type zinc finger protein 6", "gene_name": "Zfand6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQETNHSQAPMLCSTGCGFYGNPRTNGMCSVCYKEHLQRQNSSNGRISPPAASVSSLSESLPVQCADGSVPDAQSALDSTSSSMQPGPVSNQSLLSESVAPSQVDSTSVDKAVSETEDLQGPRAEGLVPLECDPPSSVSDTTQQPSEEQSKSLEKPKQKKNRCFMCRKKVGLTGFECRCGNVYCGVHRYSDVHNCSYNYKADAAEKIRKENPVVVGEKIQKI", "length": 223 }, "evidence": [ { "id": "A0A8V0Z4W8", "url": "https://omabrowser.org/oma/group/A0A8V0Z4W8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8" } ], "pmid": "" }, { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8" } ], "pmid": "" }, { "name": "cellular response to tumor necrosis factor", "id": "GO:0071356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071356", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8" } ], "pmid": "" }, { "name": "regulation of canonical NF-kappaB signal transduction", "id": "GO:0043122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043122", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8" } ], "pmid": "" }, { "name": "protein targeting to peroxisome", "id": "GO:0006625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006625", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4W8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8" }, { "id": "PS51036", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51036" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "A20-type", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 59, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z4W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4W8" }, { "id": "PS51039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51039" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AN1-type", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 206, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 148 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 23, "end_pos": 25 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z4Y3-1", "uniprot_ac": "A0A8V0Z4Y3", "uniprot_id": "A0A8V0Z4Y3_CHICK", "mass": { "chemical_mass": 218199.0, "monoisotopic_mass": 218199.0 }, "refseq": { "ac": "NP_001376306", "name": "lactase/phlorizin hydrolase precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376306" }, "gene_names": [ { "name": "LCT", "type": "recommended", "evidence": [ { "id": "A0A8V0Z4Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y3" } ] }, { "name": "GLH1", "type": "synonym", "evidence": [ { "id": "NP_001376306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376306" } ] }, { "name": "LCT", "type": "synonym", "evidence": [ { "id": "NP_001376306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376306" } ] } ], "protein_names": [ { "name": "GLH2", "type": "synonym", "evidence": [ { "id": "NP_001376306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376306" } ] }, { "name": "Lactase", "type": "synonym", "evidence": [ { "id": "A0A8V0Z4Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y3/entry#names_and_taxonomy" } ] }, { "name": "lactase-phlorizin hydrolase", "type": "synonym", "evidence": [ { "id": "NP_001376306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376306" } ] }, { "name": "lactase/phlorizin hydrolase precursor", "type": "synonym", "evidence": [ { "id": "NP_001376306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376306" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000236.1. On Dec 3, 2021 this sequence version replaced NP_001376306.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001376306", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376306" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y3" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LCT", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y3", "locus": { "chromosome": "7", "start_pos": 30265257, "end_pos": 30285317, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019823", "url": "https://www.ensembl.org/id/ENSGALG00010019823" } ] } } ], "crossref": [ { "id": "424294", "url": "https://www.ncbi.nlm.nih.gov/gene/424294", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "AHWAEPK", "url": "https://omabrowser.org/oma/group/AHWAEPK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z4Y3", "url": "https://www.orthodb.org/?gene=A0A8V0Z4Y3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZAS4", "url": "https://www.orthodb.org/?gene=A0A8V0ZAS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10353:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10353:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00232", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-189085", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189085", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001376306", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001376306", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Y3", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAS4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELVCKTVVFFLLVSTSLGIDEELAQDFVAIAGPLPTTLAHRLHLQSHILPKEALDPTVSEAHDDFCQQDTVISQLPQYFSHLREIGVTHYKVFLPWARILPDGDAKKPDEAQVRCYQELLKMLVAADLRPVIVLHHKGVPDTVAVGRKASSFADLFVDYAEFSFYVFGGLADMWLTFSDLPELLESLPYSDSQVRVQALAAAHERAYSVYHKKYSGGKLSIALGMDLILDSTSSELLSVSFQESVDFLSLSLQYWCGNETDFYLKMSEFQNVWKDTEVLLFSLKFLDCGSLEENPFIPVAAIVAAINKEKARTIGYDVNEFLDFSSRVLSKAYTLQENLSAAIAPRSSYQTVWEMFANQSELERDTFLQDVFPSGFLWGTSTGAFNIEGAWAEDGKGESIWDQFGHEGHVYMNQTTDVACDSYHKTSYDVYLLRGLHPQLYKFSISWPRIFPAGTNETIGFKGVDYYNQLIDRLLEANIEPMVTLFHWDLPQALQVLGGWQNDSIIDAFANYADFCFTTFGDRVKFWVTFHEPWVISYAGYGTGEHPPGITDPGIASYKVAHTILKAHAKVWHLYNDRYRSQQQGRVGLVLNSDWAEPQTPANSEDVKASERYLQFMLGWFAHPVFVNGDYPDILKAQIQEVNQQCSTTVAQLPVFTEEEKTWVKGTADFFGLSHYTSHLVTAVTNGTCTPGYESIGNFSLHVDPSWPKTASSSIHVVPWGLRRLLKFVSQEYTGTKIPIYIAGNGMPTEAVGDLINDTLRVDYFRRYINEALKAIKLDAVDVQSYIARSLIDGFEGPGGYSLKFGLHHVNFEDSNRPRTPKASAYFYSSVIENNGFPSKVSDRSSTSVVFGLPTPSKLPSLPASEVPSKSKVVWQKFSSQTDFERDMYVYGTFPKDFTWGVSSSAYQIEGGWDADGKGPSVWDNFTHVPGNIKNNDTGDIACNSYNKVEEDIYLLRALGVKNYRFSLSWPRIFPNGRNNSINSHGVDYYNRLIDGLVANNITPIVTLYHWDLPQALQDIGGWENSELIELFDSFADFCFQTFGDRVKFWLTFNEPQVIAWVSYGTGEFPPNVNNPGSAPYEVAHTLLKAHARVYHTYDDKYRASQGGVISLCLNIDWIEPKTPSNPRDLEAADRYMQFLVGWFAHPVFKNGDYPEVMKWTVGNRSELQNLPSSRLPVFTAEEREYIRGTADVFCLNTYTAKLVTHATTRLNPFSYEYDQEISTDVDSSWPTSALAGHRAVAWGLRRLLNWVKEEYGNPPMYIIENGVGIKTKSDVDDHTRILYYKTYIDEALKAYKLDGVNLRGYNAWSFMDFFEWLNGYEPRFGLHEVDFNDPNRPRTPRRSAVYYAEIIRNNGIPLPEENKFLYGEFPKNFCWSVATAAYQIEGAWRADGKGLSIWDKYTHTPLKISNDDNGDVACDSYHKIEEDVEMLKRLKVSHYRFSISWSRVLPDGTTRYINEMGLNYYERLIDALLAANITPQVTLYHWDLPQALQDIGGWENDTIVQRFKEYAELLFQRLGDKVKFWITLNEPYNTAYLGYGFGTAAPGISVRPGRAPYVVGHNLIKAHAEAWHLYNETYRAKQGGLISITINSDWAEPRNPHKQEDFDAARQYLQFLIGWFAHPIFKNGDYNEVMKTRIRERSLAQGLSSSRLPEFTESEKQRIKGTYDYFGLNHYTTVLAYKYEYSTGILSYDADRGVASVTDRSWLNSGSFWLKVTPFGFRKLLRWIKEEYNNPPIYVTENGVSERGAIDFNDTWRIHYYQNYINEALKAVVLDGVDLRGYTAWTLMDNFEWAVGYDERFGFYHVNYTDPTLPRLPKASTRYYSQIISCNGFPDPATGPHPCLETEPDVIPDTTPGLADSVRFLGLDLTSQRAEIALYVLFALSAIGALGLALISYKYGTISKRYHKQSSMELSKM", "length": 1919, "header": "tr|A0A8V0Z4Y3-1|A0A8V0Z4Y3_CHICK Isoform 1 of Lactase OS=Gallus gallus OX=9031 GN=LCT PE=3 SV=1 CANONICAL=A0A8V0Z4Y3-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y3/entry#A0A8V0Z4Y3-1", "sequence": { "sequence": "MELVCKTVVFFLLVSTSLGIDEELAQDFVAIAGPLPTTLAHRLHLQSHILPKEALDPTVSEAHDDFCQQDTVISQLPQYFSHLREIGVTHYKVFLPWARILPDGDAKKPDEAQVRCYQELLKMLVAADLRPVIVLHHKGVPDTVAVGRKASSFADLFVDYAEFSFYVFGGLADMWLTFSDLPELLESLPYSDSQVRVQALAAAHERAYSVYHKKYSGGKLSIALGMDLILDSTSSELLSVSFQESVDFLSLSLQYWCGNETDFYLKMSEFQNVWKDTEVLLFSLKFLDCGSLEENPFIPVAAIVAAINKEKARTIGYDVNEFLDFSSRVLSKAYTLQENLSAAIAPRSSYQTVWEMFANQSELERDTFLQDVFPSGFLWGTSTGAFNIEGAWAEDGKGESIWDQFGHEGHVYMNQTTDVACDSYHKTSYDVYLLRGLHPQLYKFSISWPRIFPAGTNETIGFKGVDYYNQLIDRLLEANIEPMVTLFHWDLPQALQVLGGWQNDSIIDAFANYADFCFTTFGDRVKFWVTFHEPWVISYAGYGTGEHPPGITDPGIASYKVAHTILKAHAKVWHLYNDRYRSQQQGRVGLVLNSDWAEPQTPANSEDVKASERYLQFMLGWFAHPVFVNGDYPDILKAQIQEVNQQCSTTVAQLPVFTEEEKTWVKGTADFFGLSHYTSHLVTAVTNGTCTPGYESIGNFSLHVDPSWPKTASSSIHVVPWGLRRLLKFVSQEYTGTKIPIYIAGNGMPTEAVGDLINDTLRVDYFRRYINEALKAIKLDAVDVQSYIARSLIDGFEGPGGYSLKFGLHHVNFEDSNRPRTPKASAYFYSSVIENNGFPSKVSDRSSTSVVFGLPTPSKLPSLPASEVPSKSKVVWQKFSSQTDFERDMYVYGTFPKDFTWGVSSSAYQIEGGWDADGKGPSVWDNFTHVPGNIKNNDTGDIACNSYNKVEEDIYLLRALGVKNYRFSLSWPRIFPNGRNNSINSHGVDYYNRLIDGLVANNITPIVTLYHWDLPQALQDIGGWENSELIELFDSFADFCFQTFGDRVKFWLTFNEPQVIAWVSYGTGEFPPNVNNPGSAPYEVAHTLLKAHARVYHTYDDKYRASQGGVISLCLNIDWIEPKTPSNPRDLEAADRYMQFLVGWFAHPVFKNGDYPEVMKWTVGNRSELQNLPSSRLPVFTAEEREYIRGTADVFCLNTYTAKLVTHATTRLNPFSYEYDQEISTDVDSSWPTSALAGHRAVAWGLRRLLNWVKEEYGNPPMYIIENGVGIKTKSDVDDHTRILYYKTYIDEALKAYKLDGVNLRGYNAWSFMDFFEWLNGYEPRFGLHEVDFNDPNRPRTPRRSAVYYAEIIRNNGIPLPEENKFLYGEFPKNFCWSVATAAYQIEGAWRADGKGLSIWDKYTHTPLKISNDDNGDVACDSYHKIEEDVEMLKRLKVSHYRFSISWSRVLPDGTTRYINEMGLNYYERLIDALLAANITPQVTLYHWDLPQALQDIGGWENDTIVQRFKEYAELLFQRLGDKVKFWITLNEPYNTAYLGYGFGTAAPGISVRPGRAPYVVGHNLIKAHAEAWHLYNETYRAKQGGLISITINSDWAEPRNPHKQEDFDAARQYLQFLIGWFAHPIFKNGDYNEVMKTRIRERSLAQGLSSSRLPEFTESEKQRIKGTYDYFGLNHYTTVLAYKYEYSTGILSYDADRGVASVTDRSWLNSGSFWLKVTPFGFRKLLRWIKEEYNNPPIYVTENGVSERGAIDFNDTWRIHYYQNYINEALKAVVLDGVDLRGYTAWTLMDNFEWAVGYDERFGFYHVNYTDPTLPRLPKASTRYYSQIISCNGFPDPATGPHPCLETEPDVIPDTTPGLADSVRFLGLDLTSQRAEIALYVLFALSAIGALGLALISYKYGTISKRYHKQSSMELSKM", "length": 1919, "header": "tr|A0A8V0Z4Y3-1|A0A8V0Z4Y3_CHICK Isoform 1 of Lactase OS=Gallus gallus OX=9031 GN=LCT PE=3 SV=1 CANONICAL=A0A8V0Z4Y3-1" }, "locus": { "chromosome": "7", "start_pos": 30282742, "end_pos": 30266876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047876.1", "url": "https://www.ensembl.org/id/ENSGALT00010047876.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028294.1", "url": "https://www.ensembl.org/id/ENSGALP00010028294.1" } ] } }, { "isoform_ac": "A0A8V0ZAS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Y3/entry#A0A8V0ZAS4-1", "sequence": { "sequence": "MLTSFGNNAVSPMEENTSKALLREHHPAFAENENYLPPLHDVSGGKLSIALGMDLILDSTSSELLSVSFQESVDFLSLSLQYWCGNETDFYLKMSEFQNVWKDTEVLLFSLKFLDCGSLEENPFIPVAAIVAAINKEKARTIGYDVNEFLDFSSRVLSKAYTLQENLSAAIAPRSSYQTVWEMFANQSELERDTFLQDVFPSGFLWGTSTGAFNIEGAWAEDGKGESIWDQFGHEGHVYMNQTTDVACDSYHKTSYDVYLLRGLHPQLYKFSISWPRIFPAGTNETIGFKGVDYYNQLIDRLLEANIEPMVTLFHWDLPQALQVLGGWQNDSIIDAFANYADFCFTTFGDRVKFWVTFHEPWVISYAGYGTGEHPPGITDPGIASYKVAHTILKAHAKVWHLYNDRYRSQQQGRVGLVLNSDWAEPQTPANSEDVKASERYLQFMLGWFAHPVFVNGDYPDILKAQIQEVNQQCSTTVAQLPVFTEEEKTWVKGTADFFGLSHYTSHLVTAVTNGTCTPGYESIGNFSLHVDPSWPKTASSSIHVVPWGLRRLLKFVSQEYTGTKIPIYIAGNGMPTEAVGDLINDTLRVDYFRRYINEALKAIKLDAVDVQSYIARSLIDGFEGPGGYSLKFGLHHVNFEDSNRPRTPKASAYFYSSVIENNGFPSKVSDRSSTSVVFGLPTPSKLPSLPASEVPSKSKVVWQKFSSQTDFERDMYVYGTFPKDFTWGVSSSAYQIEGGWDADGKGPSVWDNFTHVPGNIKNNDTGDIACNSYNKVEEDIYLLRALGVKNYRFSLSWPRIFPNGRNNSINSHGVDYYNRLIDGLVANNITPIVTLYHWDLPQALQDIGGWENSELIELFDSFADFCFQTFGDRVKFWLTFNEPQVIAWVSYGTGEFPPNVNNPGSAPYEVAHTLLKAHARVYHTYDDKYRASQGGVISLCLNIDWIEPKTPSNPRDLEAADRYMQFLVGWFAHPVFKNGDYPEVMKWTVGNRSELQNLPSSRLPVFTAEEREYIRGTADVFCLNTYTAKLVTHATTRLNPFSYEYDQEISTDVDSSWPTSALAGHRAVAWGLRRLLNWVKEEYGNPPMYIIENGVGIKTKSDVDDHTRILYYKTYIDEALKAYKLDGVNLRGYNAWSFMDFFEWLNGYEPRFGLHEVDFNDPNRPRTPRRSAVYYAEIIRNNGIPLPEENKFLYGEFPKNFCWSVATAAYQIEGAWRADGKGLSIWDKYTHTPLKISNDDNGDVACDSYHKIEEDVEMLKRLKVSHYRFSISWSRVLPDGTTRYINEMGLNYYERLIDALLAANITPQVTLYHWDLPQALQDIGGWENDTIVQRFKEYAELLFQRLGDKVKFWITLNEPYNTAYLGYGFGTAAPGISVRPGRAPYVVGHNLIKAHAEAWHLYNETYRAKQGGLISITINSDWAEPRNPHKQEDFDAARQYLQFLIGWFAHPIFKNGDYNEVMKTRIRERSLAQGLSSSRLPEFTESEKQRIKGTYDYFGLNHYTTVLAYKYEYSTGILSYDADRGVASVTDRSWLNSGSFWLKVTPFGFRKLLRWIKEEYNNPPIYVTENGVSERGAIDFNDTWRIHYYQNYINEALKAVVLDGVDLRGYTAWTLMDNFEWAVGYDERFGFYHVNYTDPTLPRLPKASTRYYSQIISCNGFPDPATGPHPCLETEPDVIPDTTPGLADSVRFLGLDLTSQRAEIALYVLFALSAIGALGLALISYKYGTISKRYHKQSSMELSKM", "length": 1746, "header": "tr|A0A8V0ZAS4-1|A0A8V0Z4Y3_CHICK Computationally mapped isoform of Lactase OS=Gallus gallus OX=9031 GN=LCT PE=3 SV=1 CANONICAL=A0A8V0Z4Y3-1" }, "locus": { "chromosome": "7", "start_pos": 30285118, "end_pos": 30266876, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047882.1", "url": "https://www.ensembl.org/id/ENSGALT00010047882.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028296.1", "url": "https://www.ensembl.org/id/ENSGALP00010028296.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-189085", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-189085", "resource": "Reactome", "description": "Digestion of dietary carbohydrate" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BK89-1", "protein_name": "Lactase/phlorizin hydrolase", "gene_name": "LCT", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELAWHLVLTVLLSFSCWGLDWDSDKNFISAAGPLTNSLLHDLRDPLGNQASPFVAEDEEIYVCRQPLPAFLPEYFRSVRASMITHYKVFLPWAQLLPEGISENPDKETVLCYRQLLEALKTAQLQPLVVLHHQTLPASTLQRTETFADLFAAYASFAFHSFGDLVEIWFTFSDLERVITKLPHQESRSSRLQMLTDAHRKAYEIYHEKYASQGGKLSVVLRAEMLSKLLLEPSMSTLVKDAVDFISLDLSYECHSEADLPQTLSELQTTEPKVKVFVFSLKLQNCLSTRNNVAHLLFSLLKAINEDQMLVIGFDISTFLSCSSSSKKSWSCSLSDSLTLQTAPQLGPDTAVYAWSPRSAYQRVWEAFANQSKAERDAFLQDVFPEGFLWGVSTGAFNVEGGWAEDGRGPSIWDRVGHQNTNKGQATPEVASDSYHKADTDVALLRGLQAQVYKFSISWSRIFPTGQGRNPNPRGVAYYNKLIDSLLDSHIEPMATLFHWDLPQALQDRGGWQSEDVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHAPGISDPGVASFKVAHMVLKAHARAWHHYNSHHRPQQQGRVGIVLNSDWAEPLSPERPEDLRAAERFLHFMLGWFAHPIFVDGDYPAALRAQIQQMNKQCPSPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISKARGDTCIPSYDTIGGFSQHVDPTWPQTASPWIRVVPWGIRRLLNFVSLEYTKGKVPIYLAGNGMPIGESEDLIDDSLRVDYFNQYINEVLKAIKEDSVVVQSYIARSFIDGFEGPSGYSQRFGLYHVNFDDSSRPRTARKSAYFFTSMIEKNGFLNKVVKRQSPPSIANVPRKIRAFSFPSEVPSKAKVVWEKFSNQPKFERDLFYHGTFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDVACDSYNHLDADLNMLQALKVKAYRFSISWSRIFPTGRNTSVNAHGVDYYNKLINGLVENNISPMVTLFHWDLPQALQDIGGWENPLLVDLFNSYADFCFQTFGDRVKFWMTFNEPTYQAWLGYGSGEFPPNVNDSGSGPYRIGHAIIKAHARVYHTYDEKYRQEQKGVISLSLSSHWAEPQSLVPRDVEAADRMLQFSLGWFAHPIFRNGDYPDAMKWKVGNRSELQHLATSRLPSFTEEEKQYIAATADVFCLNTYSSRIVQHTTPRLNPPSYTSDQELLEWEDTSWPATAMNRAAAWGMRRLLNWIKEEYGDIPVYITENGVGLTDPKLEDTDRIFYHKTYINEALKAYRLDGVNLRGYAAWSLMDNFEWLNGYTVKFGLYHVDFDDVNKSRTARASARYYTEVITNNGMPLSKEDEFLYGQFPKDFIWSAATASYQIEGAWRADGKGLSIWDTFSHTPLKVENNDTGDVACDSYHKIAEDLAALQTLGVTHYRFSISWTRILPDGTNRYINEAGLDYYVRLIDTLLAANIQPQVTIYHWDLPQALQDVGGWENETIVQRFKEYAEVLFQRLGDKVKFWITLNEPYVVAYQGYGYGTAAPGISFRPGTAPYIVGHNLIKAHAEAWHLYNDVYRARQGGVISITISSDWAEPRDPSNQEDVEAAKRYVQFMGGWFAHPIFKNGDYPEVMKTRIRDRSLAEGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYASWISSFDADRGVASITDRSWPDSGSFWLKMTPFGFRRILNWLKEEYNNPPIYVTENGVSHRGEANLNDTARIYYLRSYINEALKAAMQDKVDLRGYTVWTLMDNFEWATGFSDKFGLHFVNYTDPALPRIPRESAKVYASIIRCSGFPDPAAGPHPCLQQEDAEPTASPVRQNIQFLGLRLSTTEAQTALNVLFAFMLLGVCCVALLSYKYFKRSKQKHTQPGEQELSHRSSF", "length": 1928 }, "evidence": [ { "id": "A0A8V0Z4Y3", "url": "https://omabrowser.org/oma/group/A0A8V0Z4Y3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1Q8B5-1", "protein_name": "Lactase/phlorizin hydrolase isoform X1", "gene_name": "LOC559107", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMKILGGFLSLGVLAIFWSYINADEQEFMLLAGPLTTSQNLPSEEQYVFNCRGPLPQQSKDYFLYLQRRGVTNFKVLLSWSHILPTGDANQPHEETVMCFKTLVQQLTESGIKPLLVLHRSAVPELFRAKYGGWGNPLLVQIFEQYAGFVFSTFRDHVDTFVTFSHLHELQHEELQNALQSHENAYKVCHQQFKGLRLSLGIRASHATSIYQMGSKIMTHVDFLSVHMQFNCKMQTALTEELRKVQIVSGQKSLLIYQLTVNDCDGYEHDFQPLTVVLGVLQNKDYKIIGCDITHVFEKLDYEETPRSLQKEDAMSVFNQKSASAFSYQKVWEKFKTQTEAERDQFLSGSFPVDFEWSVSSESFKVEGGSAEHGKGETIWDRFNHEAGVNESILGCDSYHKVDYDVYLLRGMMAPNYQFSISWARIFPTGRKESFVEKGAAYYDKMINTLLQSGIEPTVTLHHWDLPQALQESGGWINDSIVEAFKEFSDFCFSRYGDRVKTWVTFGSPWVVSNLGYGTGVYPPSIKDPVSASYKVTHNILKSHAEAWHIYNDKYRKLYGGKVGIALNSDWAEPRDPSSDQDVAAAERYLNFMLGWFAHPIFVDGDYPAVLREQIEKKKKLCDQDLARLPVFTEAEKQRIQGTADFFGLNHQTSRLISENLTSCDAGPDNVGDFQAHIDPTWPTTSSDQIQSVPWGLRRLLYYIFLEYTSITKVPIYITGNGMPTEYTGDGINDTLRVDYLKAYINEAMKAVHLDDVVVQRFTVQSLMDGYEGPPGYTQRFGLHYVNFDDPDRPRTPKASAYYYSKVIERNGFAETAASPKMQIHGNQVESRRLPSLPPSQVPSKSKVVWEKFSPQTKFERQLYHYGTFSEGFQWGVSSSAYQVEGGWNADGKGPSVWDTFTQKPGNIPNNANGDVACDSYNKVDEDLHMLRALKVKTYRFSLSWSRIFPNGYKSSLNQKGVDYYNRLIDGLIANNITPMVTLYHWDLPQALQNIHWDNTEMIGLFNEYCDFCYATFGDRVKFWITFNEPQTIAWLGYGLGQIPPNVKQPGDAPYRVAHNLLKAHAQAYHTYDEKYRASQGGLVSISLNAEWAEPLDVNIPREVVAADRALQFQLGWFAHPIFKNGDYPEAMKWQVGNKSELQGLKESRLPHFTDQEKAFIQGTADVFCINTYTTKVVRHVTSRLNIESYQTDQDIEKDKADGSENTAVSEQKAVAWGLRRLLIWLKEEYGNPEIYITENGVATGTAITTDDTDRIFYLKTYVDEALKAHNLDGVRVKGYIASSLMDSFEWLNGYNVGYGLHHVDFKHSSRPRTPKRSAHLYFDIMRNNGFPMPVEEKMLYGHFREGFVWSTATAAYQIEGAWRADGKGLSIWDKFAHTSLKISQDENGDIACDSYNKIEEDIDNLKTLRVNHYRFSISWPRILPDGTNRKINEAGLNYYHRLIDVLLAANIKPQVTLYHWDLPQALQDVGGWENDTIVDRFKDYADVVFNSLGDKVEFWITINEPYNVAMVGHGYGSAAPGITFRPGTAPYIVAHNLIKAHAEAWHLYNDKYRAKHGGIVGITINSDWAEPRNPYKQEDVDAARRVVQFQLGWFAHPVFNGDYSDLMKDIVRERSLAAGLPKSRLPEFTPEEVARIKGTHDYFGFNHYTTVLAYNFDYKDLQHYDADRGVGTVTDRTWLDSGSFWLKVTPVGFRKILNFIKEEYGDHTIYITENGVSERGPVNLNDIPRIHYYDNYINQALKAYMLDGVDIRGYAAWTLMDNLEWATGFDDRFGLFYVNRSDPNLPRIPKKSVWNYATIINCNGFISPEERPHKCQVHEPEDDTPGITTIPPPVEELSISFLGLEVSVSDAELALNVLFSLSIIAAVTVILLVYGLVKASKKQKHPAGEYIDLEKKDKF", "length": 1900 }, "evidence": [ { "id": "A0A8V0Z4Y3", "url": "https://omabrowser.org/oma/group/A0A8V0Z4Y3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F8VPT3-1", "protein_name": "Lactase/phlorizin hydrolase", "gene_name": "Lct", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELPWTALFLSTFLLGLSCQGNDWESDRNFISAAGPLTNDLVHNLNHPLGKQGSDLVAGDTDIYVCQQPLPSFLPQYFSSLRASQVTHYKVLLSWAQLLPKGSSKNPDQEAVQCYRQLLQSLKDAQLQPMVVLFHQMPPTSTIQRDGGFADLFADYATLAFQSFGDLVEIWFTFSDLEKVIMGLPHQHLKASGLQTLSDAHRKAFDVYHRKYSSQGGKLSVVLKAEDLPKLLPDPSSAALVKGSVDFLSLDLSYDCQSISTLPQKLSELQNLEPKVKVFVYTLKPQDCPSTGMSPASLLFRLLEAINKDQVQTVGFDVSAFLSCTSSSEESPSCSLTYSSLALQSEQQHETVVSSFPGSAYQRVWAALANQSREERDAFLQDVFPEGFLWGVSTGAFNVEGGWAEGGRGPSIWDHYSNLNAAESQATAKVASDSYHKPVSDVALLRGLRADVYKFSISWSRIFPFGQRTSPNLQGVAYYNKLIDSLLDSQVEPMATLFHWDLPQALQEQGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVISYAGYGTGQHAPAISDPGVASFKVAHLILKAHARTWHHYNYHHRQKQQGRVGIVLNSDWAEPLDGKSPQDLAAAERYLHFMLGWFAHPIFIDGDYPAALRAQIQHTNQQCGRPLAQLPEFTEAEKRLLKGSADFLGLSHYTSRLISKAGQQTCIPSYDNIGGFSQHVDPKWPQTASPWIRVVPWGIRRLLRFASLEYTKGKLPIFLAGNGMPIGEGSDLFDDSMRVNYLNLYINEVLKAVKEDSVDVRSYIARSLIDGYEGPLGYSQRFGLYHVNFNDSSRPRTPRKSAYFFTSIIEKNGFPAKKVKRNPLPLKADFSSRARAAFSFPSEVPSKAKVVWEKFSRQPKFERDLFYHGTFRDDFLWGVSSSAYQIEGGWDADGKGPSIWDNFTHTPGNGVKDNATGDIACDSYHQLDADINILRTLKVKSYRFSISWPRIFPTGRNSSINKQGVDYYNKLIDRLLESNIFPMVTLFHWDLPQALQDIGGWENPSLIELFDSYADFCFKTFGDRVKFWMTFNEPWCSAVLGYSSGIFPPNVQDPGSLSYKVSHVIIKAHARVYHTYDEKYRQEQKGVISLSLNTHWVEPKDPGVQRDVEAADRMLQFNLGWFAHPIFKNGDYPDVMKWNVGNRSELQHLASSRLPSFTEEEKNYIRGTADVFCINTYTSVFAQHVTPRLNPPSYDNDMELKASDMNSSALISMMHQDVPWGMRRLLNWIKEEYGNIPIYITENGQGLTNPTLDDTERIFYHKTYINEALKAYRLDGVDLRGYSAWALMDNFEWLHGYTMRFGLYHVDFDHVNRPRTARASARYYTEVITNNGMPLAKEDEFLYGEFPKGFIWSAASASYQVEGAWRADGKGLSIWDTFSHTPLKIGNDDNGDVACDSYHKIAEDVVALQNLGVSHYRFSISWPRILPDGTTKFINEAGLNYYVRFIDALLAAGITPQVTMYHWDLPQALQDVGGWENETVVQRFKDYADVLFRRLGDKVKFWITLNEPFVIAAHGYGSGVSAPGISFRPGTAPYTAGHNLIKAHAEAWHLYNSTYRNSQGGVISITISSDWAEPRDPSNQEDVEAARRYVQFMGGWFAHPIFKNGDYPEVMKTRIRDRSLAAGLNKSRLPEFTESEKKKIQGTFDFFGFNHYTTVLAYNLNYAAAVSSFDADRGVASITDRSWPDSGSFWLKMTPFGFRRILNWLKEEYNNPLIYVTENGVSRRGDPELNDTDRIYYLRSYINEALKAVRDKVDLRGYTVWSIMDNFEWATGFAERFGVHFVNRSDPSLPRIPKASAKVYASIVRCNGFPDPAQGPHPCLQQPEDAGPTASPVKSEVPFLGLMLGTAEAQTALYVLFALVLLGVCSVAFLLYKYCKRSKQGTTQPGHHGLSQISSF", "length": 1931 }, "evidence": [ { "id": "A0A8V0Z4Y3", "url": "https://omabrowser.org/oma/group/A0A8V0Z4Y3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P09848-1", "protein_name": "Lactase/phlorizin hydrolase", "gene_name": "LCT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELSWHVVFIALLSFSCWGSDWESDRNFISTAGPLTNDLLHNLSGLLGDQSSNFVAGDKDMYVCHQPLPTFLPEYFSSLHASQITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEAFADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQLQTLSDAHRKAYEIYHESYAFQGGKLSVVLRAEDIPELLLEPPISALAQDTVDFLSLDLSYECQNEASLRQKLSKLQTIEPKVKVFIFNLKLPDCPSTMKNPASLLFSLFEAINKDQVLTIGFDINEFLSCSSSSKKSMSCSLTGSLALQPDQQQDHETTDSSPASAYQRIWEAFANQSRAERDAFLQDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTTEGQATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPGISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGIVLNSDWAEPLSPERPEDLRASERFLHFMLGWFAHPVFVDGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQHVNHVWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIEKNGFLTKGAKRLLPPNTVNLPSKVRAFTFPSEVPSKAKVVWEKFSSQPKFERDLFYHGTFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDPGWAPYRIAHAVIKAHARVYHTYDEKYRQEQKGVISLSLSTHWAEPKSPGVPRDVEAADRMLQFSLGWFAHPIFRNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYEDDQEMAEEEDPSWPSTAMNRAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGMPLAREDEFLYGRFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHTPLRVENDAIGDVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPGVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITISSDWAEPRDPSNQEDVEAARRYVQFMGGWFAHPIFKNGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDADRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVRCNGFPDPATGPHACLHQPDAGPTISPVRQEEVQFLGLMLGTTEAQTALYVLFSLVLLGVCGLAFLSYKYCKRSKQGKTQRSQQELSPVSSF", "length": 1927 }, "evidence": [ { "id": "A0A8V0Z4Y3", "url": "https://omabrowser.org/oma/group/A0A8V0Z4Y3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q02401-1", "protein_name": "Lactase/phlorizin hydrolase", "gene_name": "Lct", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELPWTALFLSTVLLGLSCQGSDWESDRNFISAAGPLTNDLVLNLNYPPGKQGSDVVSGNTDHLLCQQPLPSFLSQYFSSLRASQVTHYKVLLSWAQLLPTGSSKNPDQEAVQCYRQLLQSLKDAQLEPMVVLCHQTPPTSSAIQREGAFADLFADYATLAFQSFGDLVEIWFTFSDLEKVIMDLPHKDLKASALQTLSNAHRRAFEIYHRKFSSQGGKLSVVLKAEDIPELLPDPALAALVQGSVDFLSLDLSYECQSVATLPQKLSELQNLEPKVKVFIYTLKLEDCPATGTSPSSLLISLLEAINKDQIQTVGFDVNAFLSCTSNSEESPSCSLTDSLALQTEQQQETAVPSSPGSAYQRVWAAFANQSREERDAFLQDVFPEGFLWGISTGAFNVEGGWAEGGRGPSIWDHYGNLNAAEGQATAKVASDSYHKPASDVALLRGIRAQVYKFSISWSGLFPLGQKSTPNRQGVAYYNKLIDRLLDSHIEPMATLFHWDLPQALQEQGGWQNESVVEAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHAPAISDPGMASFKVAHLILKAHARTWHLYDLHHRLQQQGRVGIVLNSDLAEPLDRKSPQDLAAAERFLHFMLGWFAHPIFVDGDYPTTSAQIQHINQQCGHPLAQLPEFTEAEKRLLKGSADFLGLSHYTSRLISKAGRQTCTSSYDNIGGFSQHVDPEWPQTASPWIRVVPWGIRRLLRFASMEYTKGKLPIFLAGNGMPVGEEADLFDDSVRVNYFNWYINEVLKAVKEDLVDVRSYIVRSLIDGYEGPLGFSQRFGLYHVNFNDSSRPRTPRKSAYLFTSIIEKNGFSAKKVKRNPLPVRADFTSRARVTDSLPSEVPSKAKISVEKFSKQPRFERDLFYDGRFRDDFLWGVSSSPYQIEGGWNADGKGPSIWDNFTHTPGNGVKDNATGDVACDSYHQLDADLNILRTLKVKSYRFSISWSRIFPTGRNSTINKQGVDYYNRLIDSLVDNNIFPMVTLFHWDLPQALQDIGGWENPSLIELFDSYADYCFKTFGDRVKFWMTFNEPWCHVVLGYSSGIFPPSVQEPGWLPYKVSHIVIKAHARVYHTYDEKYRSEQKGVISLSLNTHWAEPKDPGLQRDVEAADRMLQFTMGWFAHPIFKNGDYPDVMKWTVGNRSELQHLASSRLPTFTEEEKNYVRGTADVFCHNTYTSVFVQHSTPRLNPPSYDDDMELKLIEMNSSTGVMHQDVPWGTRRLLNWIKEEYGNIPIYITENGQGLENPTLDDTERIFYHKTYINEALKAYKLDGVDLRGYSAWTLMDDFEWLLGYTMRFGLYYVDFNHVSRPRTARASARYYPDLIANNGMPLAREDEFLYGEFPKGFIWSAASASYQVEGAWRADGKGLSIWDTFSHTPLRIGNDDNGDVACDSYHKIAEDVVALQNLGVSHYRFSIAWSRILPDGTTKFINEAGLSYYVRFIDALLAAGITPQVTIYHWDLPQALQDVGGWENETIVQRFKEYADVLFQRLGDRVKFWITLNEPFVIAAQGYGTGVSAPGISFRPGTAPYIAGHNLIKAHAEAWHLYNDVYRARQGGTISITISSDWGEPRDPTNREHVEAARSYVQFMGGWFAHPIFKNGDYPEVMKTRIRDRSLGAGLNKSRLPEFTESEKSRIKGTFDFFGFNHNTTVLAYNLDYPAAFSSFDADRGVASIADSSWPVSGSFWLKVTPFGFRRILNWLKEEYNNPPIYVTENGVSRRGEPELNDTDRIYYLRSYINEALKAVHDKVDLRGYTVWSIMDNFEWATGFAERFGVHFVNRSDPSLPRIPRASAKFYATIVRCNGFPDPAQGPHPCLQQPEDAAPTASPVQSEVPFLGLMLGIAEAQTALYVLFALLLLGACSLAFLTYNTGRRSKQGNAQPSQHQLSPISSF", 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052545.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_015149942.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_015149942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149942" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CASKIN1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9", "locus": { "chromosome": "14", "start_pos": 6451214, "end_pos": 6480248, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018060", "url": "https://www.ensembl.org/id/ENSGALG00010018060" } ] } } ], "crossref": [ { "id": "cd09497", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09497", "database": "CDD", "categories": [ "Protein 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_015149942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149942", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z4Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z504", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z504", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z504-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z504-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKDQELVQAVKAEDIAAVQKLLQRPKPGKAKLLGSAKRVNVNFQDTDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGKKEPMKMVLKAGSSVNIPSDEGQIPLHLAAQHGHYDVSEMLLQHQSNPCIMDNSGKTPLDLACEFGRVGVVQLLLNSNMCAALLEPKPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKAGTALHEAALCGKTDVVRLLLDSGINAHVRNTYNQTALDIVNQFTTSQASKEIKQMLRDASAALQVRAVKDYCNNYDLTSLNVKAGDVITVLEQHADGRWKGCIHDNRTGNDRVGYFPSSLVEAISKRTGSWETVTIPQQYQKIPLPAYGAAVLNGDASSHPFHSLPPPPPPPPHSHQTLFSSFGYHRLSPSSADEPRYGQGSRGADMSPSHLSPSQGGSAAPAPTEEIWVLRKPFTGGDRSSLGSTGSVASARSSGSGQSTGSGAHALHAGSEGVKLLATVLSQKASAQDAAVGDGPAKAQDIPAGSSRSQSVASSPYAPQPPAEQQLKKMEPPSEGKSSEAVYQWLCKFQLQLYAPNFINAGYDITTISRMTPEDLTAIGVTKPGHRKKIASEINNLNIPEWLPEYKPANLALWLSMIGLSQYYKVLVENGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVKKLAELQRAELGKYEPGTLKRKAAACPEVLAIESPPPEPPECQSPKMTTFQDSELSSELQVAMTGEGPEEAPEKPANPAAPGYRSPPALGGRTRQMSSSQELLGDGPRAPASTAISKSQEYLAEGTPEGPPVPPTKELRQPRHGHSIKRASVPPVPGKPRQPFPPAAGHLTPPQTPGKPRPPSPQGPSAPHATAKVKPTPQLLPPGERPASPRSLPQSPTHRGFAYVLPQPTDGEGVPPGVPVLPVSVPVLCLPPAGEGEEEPGRPKKRAHSLNRYAASDSEQERDELLVPDAGPYATVQRRVGRSHSVRAPAGGDKNVNRSQSFAIRPKKKGPPPPPPKRSSSAISSAGMAEDFPKDGEGEVAAGTPGTEGESRQEQRRASDLGGSVDTGSAGSVRSIAAMLEMSSIGGGARALALQKPPGAGVPGKGPDGYYLQPGAPPGSPERARVATVLATVKHKEAIGLDGEVVNRRRTISGPVTGLVAAARRERADSVRSETGADGPSERLRAERGGSPDTIPFAEEGNLTIKQRPRALGPARVEAGEGLSPAHRHGDLAKVEASATLKRRIRARQSQQDSVRFILTESDTVKRRPKAKDKEPALEQAPLVVYQNGTGTVKRRPASELSGAETPPTPPPATRPDGPDFTPPSAEPKKPFKPPVSPKPVLTQPAQKVPGPPVPIPKKMPVPSPGSPEVKRVHGTPPPVSPKPTPPPTAPKPPKPHATIQSVSAGSTPTPSPARQLGAAAKPSSTPPSLCSSPAKPLSPGTQPQQVPVKPPRSAIAGPSVDSASPELVQQKLEETSASLAAALQAVEEKIKQEDSQAADSTAEAKSTGSILDDIGSMFDDLADQLDAMLE", "length": 1540, "header": "tr|A0A8V0Z4Z9-1|A0A8V0Z4Z9_CHICK Isoform 1 of CASK interacting protein 1 OS=Gallus gallus OX=9031 GN=CASKIN1 PE=4 SV=1 CANONICAL=A0A8V0Z4Z9-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z4Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9/entry#A0A8V0Z4Z9-1", "sequence": { "sequence": "MGKDQELVQAVKAEDIAAVQKLLQRPKPGKAKLLGSAKRVNVNFQDTDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGKKEPMKMVLKAGSSVNIPSDEGQIPLHLAAQHGHYDVSEMLLQHQSNPCIMDNSGKTPLDLACEFGRVGVVQLLLNSNMCAALLEPKPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKAGTALHEAALCGKTDVVRLLLDSGINAHVRNTYNQTALDIVNQFTTSQASKEIKQMLRDASAALQVRAVKDYCNNYDLTSLNVKAGDVITVLEQHADGRWKGCIHDNRTGNDRVGYFPSSLVEAISKRTGSWETVTIPQQYQKIPLPAYGAAVLNGDASSHPFHSLPPPPPPPPHSHQTLFSSFGYHRLSPSSADEPRYGQGSRGADMSPSHLSPSQGGSAAPAPTEEIWVLRKPFTGGDRSSLGSTGSVASARSSGSGQSTGSGAHALHAGSEGVKLLATVLSQKASAQDAAVGDGPAKAQDIPAGSSRSQSVASSPYAPQPPAEQQLKKMEPPSEGKSSEAVYQWLCKFQLQLYAPNFINAGYDITTISRMTPEDLTAIGVTKPGHRKKIASEINNLNIPEWLPEYKPANLALWLSMIGLSQYYKVLVENGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVKKLAELQRAELGKYEPGTLKRKAAACPEVLAIESPPPEPPECQSPKMTTFQDSELSSELQVAMTGEGPEEAPEKPANPAAPGYRSPPALGGRTRQMSSSQELLGDGPRAPASTAISKSQEYLAEGTPEGPPVPPTKELRQPRHGHSIKRASVPPVPGKPRQPFPPAAGHLTPPQTPGKPRPPSPQGPSAPHATAKVKPTPQLLPPGERPASPRSLPQSPTHRGFAYVLPQPTDGEGVPPGVPVLPVSVPVLCLPPAGEGEEEPGRPKKRAHSLNRYAASDSEQERDELLVPDAGPYATVQRRVGRSHSVRAPAGGDKNVNRSQSFAIRPKKKGPPPPPPKRSSSAISSAGMAEDFPKDGEGEVAAGTPGTEGESRQEQRRASDLGGSVDTGSAGSVRSIAAMLEMSSIGGGARALALQKPPGAGVPGKGPDGYYLQPGAPPGSPERARVATVLATVKHKEAIGLDGEVVNRRRTISGPVTGLVAAARRERADSVRSETGADGPSERLRAERGGSPDTIPFAEEGNLTIKQRPRALGPARVEAGEGLSPAHRHGDLAKVEASATLKRRIRARQSQQDSVRFILTESDTVKRRPKAKDKEPALEQAPLVVYQNGTGTVKRRPASELSGAETPPTPPPATRPDGPDFTPPSAEPKKPFKPPVSPKPVLTQPAQKVPGPPVPIPKKMPVPSPGSPEVKRVHGTPPPVSPKPTPPPTAPKPPKPHATIQSVSAGSTPTPSPARQLGAAAKPSSTPPSLCSSPAKPLSPGTQPQQVPVKPPRSAIAGPSVDSASPELVQQKLEETSASLAAALQAVEEKIKQEDSQAADSTAEAKSTGSILDDIGSMFDDLADQLDAMLE", "length": 1540, "header": "tr|A0A8V0Z4Z9-1|A0A8V0Z4Z9_CHICK Isoform 1 of CASK interacting protein 1 OS=Gallus gallus OX=9031 GN=CASKIN1 PE=4 SV=1 CANONICAL=A0A8V0Z4Z9-1" }, "locus": { "chromosome": "14", "start_pos": 6480149, "end_pos": 6452523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043678.1", "url": "https://www.ensembl.org/id/ENSGALT00010043678.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025989.1", "url": "https://www.ensembl.org/id/ENSGALP00010025989.1" } ] } }, { "isoform_ac": "A0A8V0Z504-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9/entry#A0A8V0Z504-1", "sequence": { "sequence": "MGKDQELVQAVKAEDIAAVQKLLQRPKPGKAKLLGSAKRVNVNFQDTDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGKKEPMKMVLKAGSSVNIPSDEGQIPLHLAAQHGHYDVSEMLLQHQSNPCIMDNSGKTPLDLACEFGRVGVVQLLLNSNMCAALLEPKPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKAGTALHEAALCGKTDVVRLLLDSGINAHVRNTYNQTALDIVNQFTTSQASKEIKQMLRDASAALQVRAVKDYCNNYDLTSLNVKAGDVITVLEQHADGRWKGCIHDNRTGNDRVGYFPSSLVEAISKRTGSRGADMSPSHLSPSQGGSAAPAPTEEIWVLRKPFTGGDRSSLGSTGSVASARSSGSGQSTGSGAHALHAGSEGVKLLATVLSQKASAQDAAVGDGPAKAQDIPAGSSRSQSVASSPYAPQPPAEQQLKKMEPPSEGKSSEAVYQWLCKFQLQLYAPNFINAGYDITTISRMTPEDLTAIGVTKPGHRKKIASEINNLNIPEWLPEYKPANLALWLSMIGLSQYYKVLVENGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVKKLAELQRAELGKYEPGTLKRKAAACPEVLAIESPPPEPPECQSPKMTTFQDSELSSELQVAMTGEGPEEAPEKPANPAAPGYRSPPALGGRTRQMSSSQELLGDGPRAPASTAISKSQEYLAEGTPEGPPVPPTKELRQPRHGHSIKRASVPPVPGKPRQPFPPAAGHLTPPQTPGKPRPPSPQGPSAPHATAKVKPTPQLLPPGERPASPRSLPQSPTHRGFAYVLPQPTDGEGVPPGVPVLPVSVPVLCLPPAGEGEEEPGRPKKRAHSLNRYAASDSEQERDELLVPDAGPYATVQRRVGRSHSVRAPAGGDKNVNRSQSFAIRPKKKGPPPPPPKRSSSAISSAGMAEDFPKDGEGEVAAGTPGTEGESRQEQRRASDLGGSVDTGSAGSVRSIAAMLEMSSIGGGARALALQKPPGAGVPGKGPDGYYLQPGAPPGSPERARVATVLATVKHKEAIGLDGEVVNRRRTISGPVTGLVAAARRERADSVRSETGADGPSERLRAERGGSPDTIPFAEEGNLTIKQRPRALGPARVEAGEGLSPAHRHGDLAKVEASATLKRRIRARQSQQDSVRFILTESDTVKRRPKAKDKEPALEQAPLVVYQNGTGTVKRRPASELSGAETPPTPPPATRPDGPDFTPPSAEPKKPFKPPVSPKPVLTQPAQKVPGPPVPIPKKMPVPSPGSPEVKRVHGTPPPVSPKPTPPPTAPKPPKPHATIQSVSAGSTPTPSPARQLGAAAKPSSTPPSLCSSPAKPLSPGTQPQQVPVKPPRSAIAGPSVDSASPELVQQKLEETSASLAAALQAVEEKIKQEDSQAADSTAEAKSTGSILDDIGSMFDDLADQLDAMLE", "length": 1468, "header": "tr|A0A8V0Z504-1|A0A8V0Z504_CHICK Computationally mapped isoform of CASK interacting protein 1 OS=Gallus gallus OX=9031 GN=CASKIN1 PE=4 SV=1 CANONICAL=A0A8V0Z4Z9-1" }, "locus": { "chromosome": "14", "start_pos": 6480149, "end_pos": 6452523, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043689.1", "url": "https://www.ensembl.org/id/ENSGALT00010043689.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025995.1", "url": "https://www.ensembl.org/id/ENSGALP00010025995.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1053, "start_aa": "Thr", "end_pos": 1053, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1053", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1318, "start_aa": "Thr", "end_pos": 1318, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1318", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1394, "start_aa": "Thr", "end_pos": 1394, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1394", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1398, "start_aa": "Thr", "end_pos": 1398, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1398", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1419, "start_aa": "Thr", "end_pos": 1419, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1419", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 885, "start_aa": "Thr", "end_pos": 885, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr885", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 918, "start_aa": "Thr", "end_pos": 918, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr918", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q6P9K8-1", "protein_name": "Caskin-1", "gene_name": "Caskin1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKEQELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCGKTEVVRLLLDSGINAQVRNTYSQTALDIVHQFTTSQASKEIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAIVKRAGSRTGSEPSPPQGGGSLGPSAPPEEIWVLRKPFAGGDRSGSLSNVAGGRSTGGHALHAGSEGVKLLATVLSQKSVSESSPGDSPVKPPEGSSGAARSQPPAAHAGQVYGEQPPKKLESASASASEGKSAEAVSQWLATFQLQLYAPNFTSAGYDLPTISRMTPEDLTAIGVTKPGHRKKITAEISGLNIPDWLPEHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRKLAELQKAEYSKYEGGPLRRKTPQSLEMMAIESPPPSEPAAAECQSPKMTTFQDSELSGELQAALSGPAEAGAAAVEKSSNHLPPTPRTTSRESSLSGRARHISSSQELLGDGPPGPGSPMSRSQEYLLDEGMAPGTPPKEVRSSRHGHSVKRASVPPVPGKPRQVLPSGASHFTPPQTPTKAQPGSPQALGGPHGPATAKVKPTPQLLPPTDRPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPPAPGPAPPPVPAAVPTLCLPPETDVEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGTDKNVNRSQSFAVRPRKKGPPPPPPKRSSSAMASANLADEPAPDVEAEDGRLGVRAQRRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAIRRPPEGHPTPRPASPEPGRVATVLASVKHKEAIGPDGEVVNRRRTLSGPVTGLLATARRGSGEPAEQSHFMEDGTARQRLRGPAKGEASAEGPPLARVEASATLKRRIRAKQSQQENVKFILTESDTVKRRPKAKEPDTGPEPPPPLSVYQNGTATVRRRPTSEQAGPPELPPPPPPAEPPPADLMQLPPLPLPDGNARKPVKPPVSPKPILSQPVSKIQGSPTPASKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPAKALAGLQSSSATPSPVPSPARQPPAALIKPASSPPSQSASPVKPPSPGTPALHVPAKPPRAAASVVSGPPVASDCASPGDSARQKLEETSACLAAALQAVEEKIRQEDGQGPRPSSIEEKSTGSILEDIGSMFDDLADQLDAMLE", "length": 1431 }, "evidence": [ { "id": "A0A8V0Z4Z9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4Z9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VHK2-1", "protein_name": "Caskin-1", "gene_name": "Caskin1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKEQELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNVPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCIVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDTTDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCGKTEVVRLLLDSGINAQVRNTYSQTALDIVHQFTTSQASKEIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAIVKRAGSRTGSEPSPPQGGGSLGPSAPPEEIWVLRKPFAGGDRSGSLSNVAGGRSTGGHALHAGAEGVKLLATVLSQKSVSESSPGDSPVKPPEGSSGAARSQPPAAHAGQVYGEQPPKKLESSSASEGKSAEAVSQWLATFQLQLYAPNFTSAGYDLPTISRMTPEDLTAIGVTKPGHRKKITAEISGLNIPDCLPEHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRKLAELQKAEYSKYEGGPLRRKAPQSLEMMAIESPPPSEPAAAECQSPKMTTFQDSELSGELQAALSGPAEAGAAAAEKSSNHLPATPRTTSRQESSLSGRARHMSSSQELLGDGPQGPGSPMSRSQEYLLDEGPAPGTPPKEVRSSRHGHSVKRASVPPVPGKPRQVLPSGVSHFTPPQTPTKAQPGSPQALGGPHGPATAKVKPTPQLLPPTDRPMSPRSLPQSPTHRGFAYVLPQPVEGEAGPPAPGPVPPPVPAAVPTLCLPPEADVEPRRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGTDKNVNRSQSFAVRPRKKGPPPPPPKRSSSAMASANLADEPSPDVETEDGRLGVRAQRRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAIRRPPEGHPTPRPASPDPGRVATVLASVKHKEAIGPDGEVVNRRRTLSGPVTGLLATARRGPGEPAEQSHFMEDGTARQRLRGPAKGEAGVEGPPLARVEASATLKRRIRAKQSQQENVKFILTESDTVKRRPKAKEPDIGPEPPPPLSVYQNGTATIRRRPASEQAGPPELPPPPPPAEPPPTDLMPLPPLPLPDGSARKPVKPPVSPKPILAQPVSKIQGSPTPASKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPAKALAGLQSSSATPSPVPSPARQPPAALIKPASSPPSQSASPAKPPSPGAPALQVPTKPPRAAASVVSGPPVASDCASPGDSARQKLEETSACLAAALQAVEEKIRQEDGQGPRPSSIEEKSTGSILEDIGSMFDDLADQLDAMLE", "length": 1430 }, "evidence": [ { "id": "A0A8V0Z4Z9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4Z9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WXD9-1", "protein_name": "Caskin-1", "gene_name": "CASKIN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKEQELVQAVKAEDVGTAQRLLQRPRPGKAKLLGSTKKINVNFQDPDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSGTALHEAALCGKTEVVRLLLDSGINAHVRNTYSQTALDIVHQFTTSQASREIKQLLREASAALQVRATKDYCNNYDLTSLNVKAGDIITVLEQHPDGRWKGCIHDNRTGNDRVGYFPSSLGEAIVKRAGSRAGTEPSLPQGSSSSGPSAPPEEIWVLRKPFAGGDRSGSISGMAGGRGSGGHALHAGSEGVKLLATVLSQKSVSESGPGDSPAKPPEGSAGVARSQPPVAHAGQVYGEQPPKKLEPASEGKSSEAVSQWLTAFQLQLYAPNFISAGYDLPTISRMTPEDLTAIGVTKPGHRKKIAAEISGLSIPDWLPEHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWEDLQEIGITKLGHQKKLMLAVRKLAELQKAEYAKYEGGPLRRKAPQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPRDSAAEKSTGSILDDIGSMFDDLADQLDAMLE", "length": 1431 }, "evidence": [ { "id": "A0A8V0Z4Z9", "url": "https://omabrowser.org/oma/group/A0A8V0Z4Z9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9" } ], "pmid": "" }, { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9" } ], "pmid": "" }, { "name": "regulation of postsynaptic density assembly", "id": "GO:0099151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099151", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z4Z9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1006, "end_pos": 1008, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1211, "end_pos": 1213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1297, "end_pos": 1299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z4Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 559, "end_pos": 622, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z4Z9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z4Z9" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 281, "end_pos": 347, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 885, 918, 1053, 1318, 1394, 1398, 1419 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1006, "end_pos": 1008 }, { "start_pos": 1211, "end_pos": 1213 }, { "start_pos": 1297, "end_pos": 1299 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 327, "end_pos": 329 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 7 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 7 }, { "field": "exact_o_linked_sites", "count": 7 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 7 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 7 }, { "field": "exact_o_linked_sites", "count": 7 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z503-1", "uniprot_ac": "A0A8V0Z503", "uniprot_id": "A0A8V0Z503_CHICK", "mass": { "chemical_mass": 101784.0, "monoisotopic_mass": 101784.0 }, "refseq": { "ac": "XP_004942988", "name": "coiled-coil domain-containing protein 14 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942988" }, "gene_names": [ { "name": "CCDC14", "type": "recommended", "evidence": [ { "id": "A0A8V0Z503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z503" } ] }, { "name": "CCDC14", "type": "synonym", "evidence": [ { "id": "XP_004942988", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942988" } ] } ], "protein_names": [ { "name": "Coiled-coil domain containing 14", "type": "synonym", "evidence": [ { "id": "A0A8V0Z503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z503/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 14 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_004942988", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942988" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052538.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Apr 10, 2021 this sequence version replaced XP_004942988.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_004942988", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942988" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z503", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z503" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CCDC14", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z503", "locus": { "chromosome": "7", "start_pos": 26996345, "end_pos": 27008983, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019854", "url": "https://www.ensembl.org/id/ENSGALG00010019854" } ] } } ], "crossref": [ { "id": "A0A8V0Z503", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z503", "database": "AlphaFoldDB", "categories": [] }, { "id": "424252", "url": "https://www.ncbi.nlm.nih.gov/gene/424252", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:424252", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424252", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8V0Z503", "url": "https://www.orthodb.org/?gene=A0A8V0Z503", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0ZCA4", "url": "https://www.orthodb.org/?gene=A0A8V0ZCA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22367", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22367", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22367:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22367:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15254", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15254", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_004942988", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004942988", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z503", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z503", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z503-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z503-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCA4", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAMGRAGAARPCKALSSGRLTGAAKQTDGRKQPGLRKGCRSDVEAGYCLYSTDSEDQVNTIHNGLDRCAALLKNILENEATAVGKETIHKQPGKTSVKITSKPLLTKANTLKKKGLKQSITAPHIRKEIVPTSAKKLLSSTTPSIEKELPSAAQHQLVRPTHVPCSQQSPVIREKLCEHVQTQMALITGQKSQSNNEIPTVTSFPTSDHDLSLQHAAHPLSTQAGVPIDSGNQCVPQMGETVVSPMVSAAPTPAQIQSANSLPGVMSYVASGASSNSAVPTFTPLSSGREMTPSHEQQSKEADLIRCIKAHLALLQTCEVANGRTEQKLCHCLAACNISSNDEDASEEHSEDVVSEGELNALDVASARDANSQQSCVKKGLKPRQESADKTAHKVKMVKYLLGELRALITDQDDSEMLRLMNEIEDCISLLPAVVGSTNIQTEIALALQPLRSENAQLRRRLRILNQQLREQERNEKTSGQSCNYELASLQSLNVMLQTQLKESLKGLESLQAKNEELLKIIESQKEENKHLAKDIQEKEKELLENKQQYDIRSTKVKIEVEEALANVKSLQFKLEASEKENKILGITLRQRDAEVNRLRELTRTLQGSMAKLLSDLTADNVRPTSEKGLSKSLLDDHEKQMQPDPCPGNTSVMTYLKKLEMDHVLIDAELQFSNKDGELQMLNQAYEKFSGERAEINHIFTEERASASKVLPTSLKQDAETASDSGTLVDEQNKLDETVYIPLTSSASKKQLVSERTNALPHVRGPCKMFSYNCELSNSIQQNRSEVSKDPSILDTLSAGYSMKKAVENTLEITGDKVKSGDKVQMRPKGTSSGAAKDFPDKPGQLQPHVPMLFQKEISQKKGSEVGDVSFISFDDISGKSEWSASSFSTFTSRDEEDFKNGLAALDANIARLQRTLQNSIMKQQV", "length": 927, "header": "tr|A0A8V0Z503-1|A0A8V0Z503_CHICK Isoform 1 of Coiled-coil domain containing 14 OS=Gallus gallus OX=9031 GN=CCDC14 PE=4 SV=1 CANONICAL=A0A8V0Z503-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z503-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z503/entry#A0A8V0Z503-1", "sequence": { "sequence": "MAMGRAGAARPCKALSSGRLTGAAKQTDGRKQPGLRKGCRSDVEAGYCLYSTDSEDQVNTIHNGLDRCAALLKNILENEATAVGKETIHKQPGKTSVKITSKPLLTKANTLKKKGLKQSITAPHIRKEIVPTSAKKLLSSTTPSIEKELPSAAQHQLVRPTHVPCSQQSPVIREKLCEHVQTQMALITGQKSQSNNEIPTVTSFPTSDHDLSLQHAAHPLSTQAGVPIDSGNQCVPQMGETVVSPMVSAAPTPAQIQSANSLPGVMSYVASGASSNSAVPTFTPLSSGREMTPSHEQQSKEADLIRCIKAHLALLQTCEVANGRTEQKLCHCLAACNISSNDEDASEEHSEDVVSEGELNALDVASARDANSQQSCVKKGLKPRQESADKTAHKVKMVKYLLGELRALITDQDDSEMLRLMNEIEDCISLLPAVVGSTNIQTEIALALQPLRSENAQLRRRLRILNQQLREQERNEKTSGQSCNYELASLQSLNVMLQTQLKESLKGLESLQAKNEELLKIIESQKEENKHLAKDIQEKEKELLENKQQYDIRSTKVKIEVEEALANVKSLQFKLEASEKENKILGITLRQRDAEVNRLRELTRTLQGSMAKLLSDLTADNVRPTSEKGLSKSLLDDHEKQMQPDPCPGNTSVMTYLKKLEMDHVLIDAELQFSNKDGELQMLNQAYEKFSGERAEINHIFTEERASASKVLPTSLKQDAETASDSGTLVDEQNKLDETVYIPLTSSASKKQLVSERTNALPHVRGPCKMFSYNCELSNSIQQNRSEVSKDPSILDTLSAGYSMKKAVENTLEITGDKVKSGDKVQMRPKGTSSGAAKDFPDKPGQLQPHVPMLFQKEISQKKGSEVGDVSFISFDDISGKSEWSASSFSTFTSRDEEDFKNGLAALDANIARLQRTLQNSIMKQQV", "length": 927, "header": "tr|A0A8V0Z503-1|A0A8V0Z503_CHICK Isoform 1 of Coiled-coil domain containing 14 OS=Gallus gallus OX=9031 GN=CCDC14 PE=4 SV=1 CANONICAL=A0A8V0Z503-1" }, "locus": { "chromosome": "7", "start_pos": 27004960, "end_pos": 26996664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047953.1", "url": "https://www.ensembl.org/id/ENSGALT00010047953.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028314.1", "url": "https://www.ensembl.org/id/ENSGALP00010028314.1" } ] } }, { "isoform_ac": "A0A8V0ZCA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z503/entry#A0A8V0ZCA4-1", "sequence": { "sequence": "MQALSSGRLTGAAKQTDGRKQPGLRKGCRSDVEAGYCLYSTDSEDQVNTIHNGLDRCAALLKNILENEATAVGKETIHKQPGKTSVKITSKPLLTKANTLKKKGLKQSITAPHIRKEIVPTSAKKLLSSTTPSIEKELPSAAQHQLVRPTHVPCSQQSPVIREKLCEHVQTQMALITGQKSQSNNEIPTVTSFPTSDHADLSLQHAAHPLSTQAGVPIDSGNQCVPQMGETVVSPMVSAAPTPAQIQSANSLPGVMSYVASGASSNSAVPTFTPLSSGREMTPSHEQQSKEADLIRCIKAHLALLQTCEVANGRTEQKLCHCLAACNISSNDEDASEEHSEDVVSEGELNALDVASARDANSQQSCVKKGLKPRQESADKTAHKVKMVKYLLGELRALITDQDDSEMLRLMNEIEDCISLLPAVVGSTNIQTEIALALQPLRSENAQLRRRLRILNQQLREQERNEKTSGQSCNYELASLQSLNVMLQTQLKESLKGLESLQAKNEELLKIIESQKEENKHLAKDIQEKEKELLENKQQYDIRSTKVKIEVEEALANVKSLQFKLEASEKENKILGITLRQRDAEVNRLRELTRTLQGSMAKLLSDLTADNVRPTSEKGLSKSLLDDHEKQMQPDPCPGNTSVMTYLKKLEMDHVLIDAELQFSNKDGELQMLNQAYEKFSGERAEINHIFTEERASASKVLPTSLKQDAETASDSGTLVDEQNKLDETVYIPLTSSASKKQLVSERTNALPHVRGPCKMFSYNCELSNSIQQNRSEVSKDPSILDTLSAGYSMKKAVENTLEITGDKVKSGDKVQMRPKGTSSGAAKDFPDKPGQLQPHVPMLFQKEISQKKGSEVGDVSFISFDDISGKSEWSASSFSTFTSRDEEDFKNGLAALDANIARLQRTLQNSIMKQQV", "length": 917, "header": "tr|A0A8V0ZCA4-1|A0A8V0Z503_CHICK Computationally mapped isoform of Coiled-coil domain containing 14 OS=Gallus gallus OX=9031 GN=CCDC14 PE=4 SV=1 CANONICAL=A0A8V0Z503-1" }, "locus": { "chromosome": "7", "start_pos": 27008929, "end_pos": 26996664, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010047960.1", "url": "https://www.ensembl.org/id/ENSGALT00010047960.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028317.1", "url": "https://www.ensembl.org/id/ENSGALP00010028317.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 252, "start_aa": "Thr", "end_pos": 252, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr252", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "gga:424252", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:424252", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z503", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z503" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to centrosome", "id": "GO:0071539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071539", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z503", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z503" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 784, "end_pos": 786, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 252 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 337, "end_pos": 339 }, { "start_pos": 650, "end_pos": 652 }, { "start_pos": 784, "end_pos": 786 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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{ "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", 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"synonym", "evidence": [ { "id": "NP_001382977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382977" } ] } ], "protein_names": [ { "name": "CCR4-NOT transcription complex, subunit 2", "type": "synonym", "evidence": [ { "id": "NP_001382977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382977" } ] }, { "name": "Gnot2 homeodomain protein", "type": "synonym", "evidence": [ { "id": "NP_001382977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382977" }, { "id": "A0A8V0Z511", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein", "type": "synonym", "evidence": [ { "id": "NP_001382977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382977" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: X98049.1, CR389878.1 [ECO:0000332] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000077.1, X98049.1 and CR389878.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001382977", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382977" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z511", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "GNOT2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511", "locus": { "chromosome": "4", "start_pos": 89319455, "end_pos": 89321979, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018266", "url": "https://www.ensembl.org/id/ENSGALG00010018266" } ] } } ], "crossref": [ { "id": "A0A8V0Z511", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z511", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "396117", "url": "https://www.ncbi.nlm.nih.gov/gene/396117", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GHSPKAP", "url": "https://omabrowser.org/oma/group/GHSPKAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z511", "url": "https://www.orthodb.org/?gene=A0A8V0Z511", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z516", "url": "https://www.orthodb.org/?gene=A0A8V0Z516", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24339:SF67", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24339:SF67", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001382977", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001382977", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z511", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z511-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z516", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z516", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z516-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z516-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPPAPPPPARPGQAFTIAALLGRSSPPPAPPPPPTPPLPPLPHWGAPPGPLCAACCGPPPAWAARLGATGFLLSKCCFPIFKTKAGKAKRVRTIFTSDQLARLEKEFARQQYMVGTERCLLASALHLTEEQVKVWFQNRRIKWRKQSLEQQQAKLAKMGLATPQRSPDSQSHRGDEDKDCPMGAEDLREDTGSPLGSGAAPPSAQTVAKCC", "length": 212, "header": "tr|A0A8V0Z511-1|A0A8V0Z511_CHICK Isoform 1 of Gnot2 homeodomain protein OS=Gallus gallus OX=9031 GN=GNOT2 PE=4 SV=1 CANONICAL=A0A8V0Z511-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z511-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511/entry#A0A8V0Z511-1", "sequence": { "sequence": "MPPPAPPPPARPGQAFTIAALLGRSSPPPAPPPPPTPPLPPLPHWGAPPGPLCAACCGPPPAWAARLGATGFLLSKCCFPIFKTKAGKAKRVRTIFTSDQLARLEKEFARQQYMVGTERCLLASALHLTEEQVKVWFQNRRIKWRKQSLEQQQAKLAKMGLATPQRSPDSQSHRGDEDKDCPMGAEDLREDTGSPLGSGAAPPSAQTVAKCC", "length": 212, "header": "tr|A0A8V0Z511-1|A0A8V0Z511_CHICK Isoform 1 of Gnot2 homeodomain protein OS=Gallus gallus OX=9031 GN=GNOT2 PE=4 SV=1 CANONICAL=A0A8V0Z511-1" }, "locus": { "chromosome": "4", "start_pos": 89321971, "end_pos": 89319873, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044088.1", "url": "https://www.ensembl.org/id/ENSGALT00010044088.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026207.1", "url": "https://www.ensembl.org/id/ENSGALP00010026207.1" } ] } }, { "isoform_ac": "A0A8V0Z516-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511/entry#A0A8V0Z516-1", "sequence": { "sequence": "MPPPAPPPPARPGQAFTIAALLGRSSPPPAPPPPPTPPLPPLPHWGAPPGPLCAACCGPPPAWAARLGATGFLLSKCCFPIFKTKAGKAKRVRTIFTSDQLARLEKEFARQQYMVGTERCLLASALHLTEEQVKVWFQNRRIKWRKQSLEQQQAKLPAPLKEPKLC", "length": 166, "header": "tr|A0A8V0Z516-1|A0A8V0Z516_CHICK Computationally mapped isoform of Gnot2 homeodomain protein OS=Gallus gallus OX=9031 GN=GNOT2 PE=4 SV=1 CANONICAL=A0A8V0Z511-1" }, "locus": { "chromosome": "4", "start_pos": 89321971, "end_pos": 89319458, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044095.1", "url": "https://www.ensembl.org/id/ENSGALT00010044095.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026213.1", "url": "https://www.ensembl.org/id/ENSGALP00010026213.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": 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"https://www.uniprot.org/uniprotkb/A0A8V0Z511" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z511", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z511", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z511", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511" } ], "pmid": "" }, { "name": "notochord formation", "id": "GO:0014028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014028", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z511", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z511", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z511", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z511", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z511", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z511" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 87, "end_pos": 147, "start_aa": "Gly", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 36 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z525-1", "uniprot_ac": "A0A8V0Z525", "uniprot_id": "A0A8V0Z525_CHICK", "mass": { "chemical_mass": 55619.0, "monoisotopic_mass": 55619.0 }, "refseq": { "ac": "NP_001264409", "name": "zinc finger protein 639", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264409" }, "gene_names": [ { "name": "ZNF639", "type": "recommended", "evidence": [ { "id": "A0A8V0Z525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ] }, { "name": "ZNF639", "type": "synonym", "evidence": [ { "id": "NP_001264409", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264409" } ] } ], "protein_names": [ { "name": "Zinc finger protein 639", "type": "recommended", "evidence": [ { "id": "A0A8V0Z525", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 639", "type": "synonym", "evidence": [ { "id": "NP_001264409", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264409" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: HAEK01006180.1, HAEL01003863.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000240.1. On Apr 10, 2013 this sequence version replaced XP_423061.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001264409", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264409" } ] }, { "annotation": "Binds DNA and may function as a transcriptional repressor.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525#function" }, { "database": "UniProtKB", "id": "ARBA00059986", "url": "https://www.uniprot.org/uniprotkb/ARBA00059986#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ZNF639", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525", "locus": { "chromosome": "9", "start_pos": 17231939, "end_pos": 17237138, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018275", "url": "https://www.ensembl.org/id/ENSGALG00010018275" } ] } } ], "crossref": [ { "id": "A0A8V0Z525", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z525", "database": "AlphaFoldDB", "categories": [] }, { "id": "425280", "url": "https://www.ncbi.nlm.nih.gov/gene/425280", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:425280", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425280", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDINRGR", "url": "https://omabrowser.org/oma/group/PDINRGR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z525", "url": "https://www.orthodb.org/?gene=A0A8V0Z525", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24388:SF54", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24388:SF54", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001264409", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001264409", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z525-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEHPKKRKRKTLHPSRYSDSSGAPKYIDNSGIFSDHCYSVCSMKQPDIKYSENRGRYHSPVQSIDTDDDGSPVHAGTSQWSGSHSNIGLHYTDPKKKDKDKAANNGTCKDVCDSPIFSDSPTEEEKPLDIQTVEISTTEVNAVEVHDIETQTVSPEKLEAEDLEEIPLETCKIFEKNQALNITAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKTCADTHVCKVCKESFSSKVQLIEHVKLHEEDPYICKYCDYKTVIFENLSQHIADTHFNDHLYWCEQCDMQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACRLIELSDSYHNKERGQYSLINKISFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSGMLEYCKHLSSHLSEGIYLCQYCEYSTGQIEDLKTHLDFRHSTDLPHKCTDCLMRFGNEKDLLSHLQIHETA", "length": 482, "header": "tr|A0A8V0Z525-1|A0A8V0Z525_CHICK Isoform 1 of Zinc finger protein 639 OS=Gallus gallus OX=9031 GN=ZNF639 PE=3 SV=1 CANONICAL=A0A8V0Z525-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z525-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525/entry#A0A8V0Z525-1", "sequence": { "sequence": "MNEHPKKRKRKTLHPSRYSDSSGAPKYIDNSGIFSDHCYSVCSMKQPDIKYSENRGRYHSPVQSIDTDDDGSPVHAGTSQWSGSHSNIGLHYTDPKKKDKDKAANNGTCKDVCDSPIFSDSPTEEEKPLDIQTVEISTTEVNAVEVHDIETQTVSPEKLEAEDLEEIPLETCKIFEKNQALNITAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKTCADTHVCKVCKESFSSKVQLIEHVKLHEEDPYICKYCDYKTVIFENLSQHIADTHFNDHLYWCEQCDMQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACRLIELSDSYHNKERGQYSLINKISFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSGMLEYCKHLSSHLSEGIYLCQYCEYSTGQIEDLKTHLDFRHSTDLPHKCTDCLMRFGNEKDLLSHLQIHETA", "length": 482, "header": "tr|A0A8V0Z525-1|A0A8V0Z525_CHICK Isoform 1 of Zinc finger protein 639 OS=Gallus gallus OX=9031 GN=ZNF639 PE=3 SV=1 CANONICAL=A0A8V0Z525-1" }, "locus": { "chromosome": "9", "start_pos": 17236097, "end_pos": 17233587, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044110.1", "url": "https://www.ensembl.org/id/ENSGALT00010044110.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026224.1", "url": "https://www.ensembl.org/id/ENSGALP00010026224.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:425280", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:425280", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V4T2-1", "protein_name": "Zinc finger protein 639", "gene_name": "ZNF639", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNEYPKKRKRKTLHPSRYSDSSGISRIADGFNGIFSDHCYSVCSMRQPDLKYFDNKDDDSDTETSNDLPKFTDGIKARNRNQNYLVPSPVLRILDHTAFSTEKSADIEICDEECDSPESVNQQTQEESAIEVHTAEDVPIAAEVHAISEDYDIEAENNSSESLQDQTDEEPPAKLCKILDKSQALNVTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKRTDSNVCRVCKESFSTNMLLIEHAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACKLIELSDKYNNGEHGQYSLLSKITFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSSMLEYCKHLNSHLSEGIYLCQYCEYSTGQIEDLKIHLDFKHSADLPHKCSDCLMRFGNERELISHLPVHETS", "length": 485 }, "evidence": [ { "id": "A0A8V0Z525", "url": "https://omabrowser.org/oma/group/A0A8V0Z525/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A5PK30-1", "protein_name": "Zinc finger protein 639", "gene_name": "ZNF639", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNEYPKKRKRKTLHPSRYSDSSGISRIADGFNGIFSDHCYSVCSMRQPDLKYFDNKDDDSDTETSNELPKFTDGIKARNRNQNYLVPSPVLRILDHTAFPTEKSADIEICDEDCDSPESVHQQTQEESPIEVHTAEDVPIAAEVHAISEDYDIETENNSSESLQDQTDEEPPAKLCKIVDKSQALNVTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKRTDSNVCRVCKESFSTNMLLIEHAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACKLIELSDKYNNGEHGQYSLLSKITFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSSMLEYCKHLNSHLSEGIYLCQYCEYSTGQIEDLKIHLDFKHSADLPHKCSDCLMRFGNERELISHLPVHETT", "length": 485 }, "evidence": [ { "id": "A0A8V0Z525", "url": "https://omabrowser.org/oma/group/A0A8V0Z525/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99KZ6-1", "protein_name": "Zinc finger protein 639", "gene_name": "Znf639", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNEYPKKRKRKTLHPSRYSDSSGISRIADGVSGIFSDHCYSVCSMRQPDLKYFDNKDDDSDPETANDLPKFADGTKARNRNQSYLVPSPVLRILDHTVFSTEKSTEVEICDEECASPESVHQHTQEESPIEVHTSEDVPIAVEVHAISEDYDIEAENNSSESLQDQADEEPPAKLCKILDKGQALNVTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHVILKHKRTDSNVCRVCKESFSTNMLLIEHAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSRDEQYLCQFCEHETGDPEDLHSHVVNEHARRLIELSDKCGSGGHGQCSLLSKITFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSSMLEYCKHLNSHLSEGIYLCQYCEYSTGQIDDLKIHLDFKHSADLPHKCSECLMRFGNERDLLGHLQVHETT", "length": 485 }, "evidence": [ { "id": "A0A8V0Z525", "url": "https://omabrowser.org/oma/group/A0A8V0Z525/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UID6-1", "protein_name": "Zinc finger protein 639", "gene_name": "ZNF639", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNEYPKKRKRKTLHPSRYSDSSGISRIADGFNGIFSDHCYSVCSMRQPDLKYFDNKDDDSDTETSNDLPKFADGIKARNRNQNYLVPSPVLRILDHTAFSTEKSADIVICDEECDSPESVNQQTQEESPIEVHTAEDVPIAVEVHAISEDYDIETENNSSESLQDQTDEEPPAKLCKILDKSQALNVTAQQKWPLLRANSSGLYKCELCEFNSKYFSDLKQHMILKHKRTDSNVCRVCKESFSTNMLLIEHAKLHEEDPYICKYCDYKTVIFENLSQHIADTHFSDHLYWCEQCDVQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACKLIELSDKYNNGEHGQYSLLSKITFDKCKNFFVCQVCGFRSRLHTNVNRHVAIEHTKIFPHVCDDCGKGFSSMLEYCKHLNSHLSEGIYLCQYCEYSTGQIEDLKIHLDFKHSADLPHKCSDCLMRFGNERELISHLPVHETT", "length": 485 }, "evidence": [ { "id": "A0A8V0Z525", "url": "https://omabrowser.org/oma/group/A0A8V0Z525/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "pmid": "" }, { "name": "positive regulation of cell growth", "id": "GO:0030307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030307", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "pmid": "" }, { "name": "symbiont entry into host cell", "id": "GO:0046718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046718", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "pmid": "" }, { "name": "host-mediated suppression of viral transcription", "id": "GO:0043922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043922", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z525", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z525" } ], "pmid": "" }, { "name": "host-mediated activation of viral transcription", "id": "GO:0043923", "url": 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"uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 230, "end_pos": 257, "start_aa": "His", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 271, "end_pos": 273 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z535-1", "uniprot_ac": "A0A8V0Z535", "uniprot_id": "A0A8V0Z535_CHICK", "mass": { "chemical_mass": 95503.0, "monoisotopic_mass": 95503.0 }, "refseq": { "ac": "XP_040539911", "name": "rho GTPase-activating protein 17 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539911" }, "gene_names": [ { "name": "ARHGAP17", "type": "recommended", "evidence": [ { "id": "A0A8V0Z535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535" } ] }, { "name": "ARHGAP17", "type": "synonym", "evidence": [ { "id": "XP_040539911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539911" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 17", "type": "recommended", "evidence": [ { "id": "A0A8V0Z535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 17", "type": "synonym", "evidence": [ { "id": "A0A8V0Z535", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 17 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_040539911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539911" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Gallus gallus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 9.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_052586.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_040539911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539911" } ] }, { "annotation": "Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z535", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535#function" }, { "database": "UniProtKB", "id": "ARBA00055904", "url": "https://www.uniprot.org/uniprotkb/ARBA00055904#function" }, { "database": "UniProtKB", "id": "A0A8V0Z545", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z545#function" }, { "database": "UniProtKB", "id": "A0A8V0Z5M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M0#function" }, { "database": "UniProtKB", "id": "A0A8V0Z6M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M6#function" }, { "database": "UniProtKB", "id": "A0A8V0ZCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z535", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "ARHGAP17", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535", "locus": { "chromosome": "14", "start_pos": 6584272, "end_pos": 6623749, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018276", "url": "https://www.ensembl.org/id/ENSGALG00010018276" } ] } } ], "crossref": [ { "id": "A0A8V0Z535", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z535", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04386", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04386", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07618", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07618", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "416564", "url": "https://www.ncbi.nlm.nih.gov/gene/416564", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "REHRRSW", "url": "https://omabrowser.org/oma/group/REHRRSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z535", "url": 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Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03114", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03114", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013404", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-GGA-9013423", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_040539911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_040539911", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z535", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z535-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z545", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z545", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z545-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z545-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5M0", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5M0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6M6", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z6M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z6M6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZCJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZCJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSVFHIAQKRLIACFQGQYGTDPDKRHKKLPLTALAQNMQEGSAQLSDETLLGKMLDTCGDAENKLALELSQHEVQIEKDILEPLNTLTEVEIPNIQKQRKQLAKLVLDWDSARGRYNQAHKTSGTNFQMHPSKIDSLKEEMDEAGNKVEQCKDQLAADMYNFVSKEGEYAKFFVMLLEAQADYHRKALAVIEKVLPEIQAHQDKWTEKPAFGTPLEEHLKRSGREIAIPIEACVMMLLETGMREEGLFRIAAGASKLKKLKAALDCSTSQLDEFYSDPHAVAGALKSYLRELPEPLMTYALYEEWTQAANIQDQDKKLQELWKICNKLPKHYHANFRYLIKFLAKLAQNSDVNKMTPSNVAIVLGPNLLWAKTEGSLAEMAAATSVHVVAIIEPIIQHADWFFPGDQDFNVSGAFVAVPAVNSNHLSHTGNEYDSGTLERKRPVSMAVMEGDLLKKESFGVKVMDFQANPRRCGTINRKHTSPAFQPPLPPTEAGVLAHSGVEQHSQAAVAETSPVGAGFALSAGTAEQLQSQGNEDVSTSKPKDSTSSATPPPMRNGGHVSTAPNQSASSTNQLSVNQPQNAAGPSPHSMRRAVKKPAPAPPKPANPPPGQPGSQSSAPAAQPPSISPKPLARSSSPPAQHANQGAAMTSSSQVSAPRRYSSSLSPIQAPSHPPPQPPTQATPPLQPKANNQASPSAPSSEHGPEQPCYTPPQTPTPPDTPPLGKHSTTSPPSQPQSSTQDTSQSHSPPHSGTLPRPRPVPKPRNRPSVPPPPHPPSQLAGDGIIANPTQTASKIVTDSNSSIPEPLQNASAELPTEAAGKELHNHLALDIDNDTESTAL", "length": 881, "header": "tr|A0A8V0Z535-1|A0A8V0Z535_CHICK Isoform 1 of Rho GTPase-activating protein 17 OS=Gallus gallus OX=9031 GN=ARHGAP17 PE=1 SV=1 CANONICAL=A0A8V0Z535-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z535-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535/entry#A0A8V0Z535-1", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSVFHIAQKRLIACFQGQYGTDPDKRHKKLPLTALAQNMQEGSAQLSDETLLGKMLDTCGDAENKLALELSQHEVQIEKDILEPLNTLTEVEIPNIQKQRKQLAKLVLDWDSARGRYNQAHKTSGTNFQMHPSKIDSLKEEMDEAGNKVEQCKDQLAADMYNFVSKEGEYAKFFVMLLEAQADYHRKALAVIEKVLPEIQAHQDKWTEKPAFGTPLEEHLKRSGREIAIPIEACVMMLLETGMREEGLFRIAAGASKLKKLKAALDCSTSQLDEFYSDPHAVAGALKSYLRELPEPLMTYALYEEWTQAANIQDQDKKLQELWKICNKLPKHYHANFRYLIKFLAKLAQNSDVNKMTPSNVAIVLGPNLLWAKTEGSLAEMAAATSVHVVAIIEPIIQHADWFFPGDQDFNVSGAFVAVPAVNSNHLSHTGNEYDSGTLERKRPVSMAVMEGDLLKKESFGVKVMDFQANPRRCGTINRKHTSPAFQPPLPPTEAGVLAHSGVEQHSQAAVAETSPVGAGFALSAGTAEQLQSQGNEDVSTSKPKDSTSSATPPPMRNGGHVSTAPNQSASSTNQLSVNQPQNAAGPSPHSMRRAVKKPAPAPPKPANPPPGQPGSQSSAPAAQPPSISPKPLARSSSPPAQHANQGAAMTSSSQVSAPRRYSSSLSPIQAPSHPPPQPPTQATPPLQPKANNQASPSAPSSEHGPEQPCYTPPQTPTPPDTPPLGKHSTTSPPSQPQSSTQDTSQSHSPPHSGTLPRPRPVPKPRNRPSVPPPPHPPSQLAGDGIIANPTQTASKIVTDSNSSIPEPLQNASAELPTEAAGKELHNHLALDIDNDTESTAL", "length": 881, "header": "tr|A0A8V0Z535-1|A0A8V0Z535_CHICK Isoform 1 of Rho GTPase-activating protein 17 OS=Gallus gallus OX=9031 GN=ARHGAP17 PE=1 SV=1 CANONICAL=A0A8V0Z535-1" }, "locus": { "chromosome": "14", "start_pos": 6623634, "end_pos": 6585030, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044124.1", "url": "https://www.ensembl.org/id/ENSGALT00010044124.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026234.1", "url": "https://www.ensembl.org/id/ENSGALP00010026234.1" } ] } }, { "isoform_ac": "A0A8V0Z545-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535/entry#A0A8V0Z545-1", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSVFHIAQKRLIACFQGQYGTDPDKRHKKLPLTALAQNMQEGSAQLSDETLLGKMLDTCGDAENKLALELSQHEVQIEKDILEPLNTLTEVEIPNIQKQRKQLAKLVLDWDSARGRYNQAHKTSGTNFQMHPSKIDSLKEEMDEAGNKVEQCKDQLAADMYNFVSKEGEYAKFFVMLLEAQADYHRKALAVIEKVLPEIQAHQDKWTEKPAFGTPLEEHLKRSGREIAIPIEACVMMLLETGMREEGLFRIAAGASKLKKLKAALDCSTSQLDEFYSDPHAVAGALKSYLRELPEPLMTYALYEEWTQAANIQDQDKKLQELWKICNKLPKHYHANFRYLIKFLAKLAQNSDVNKMTPSNVAIVLGPNLLWAKTEGSLAEMAAATSVHVVAIIEPIIQHADWFFPGDQDFNVSGAFVAVPAVNSNHLSHTGNEYDSGTLERKRPVSMAVMEGDLLKKESTSKPKDSTSSATPPPMRNGGHVSTAPNQSASSTNQLSVNQPQNAAGPSPHSMRRAVKKPAPAPPKPANPPPGQPGSQSSAPAAQPPSISPKPLARSSSPPAQHANQGAAMTSSSQVSAPRRYSSSLSPIQAPSHPPPQPPTQATPPLQPKANNQASPSAPSSEHGPEQPCYTPPQTPTPPDTPPLGKHSTTSPPSQPQSSTQDTSQSHSPPHSGTLPRPRPVPKPRNRPSVPPPPHPPSQLAGDGIIANPTQTASKIVTDSNSSIPEPLQNASAELPTEAAGKELHNHLALDIDNDTESTAL", "length": 800, "header": "tr|A0A8V0Z545-1|A0A8V0Z545_CHICK Computationally mapped isoform of Rho GTPase-activating protein 17 OS=Gallus gallus OX=9031 GN=ARHGAP17 PE=1 SV=1 CANONICAL=A0A8V0Z535-1" }, "locus": { "chromosome": "14", "start_pos": 6623634, "end_pos": 6585030, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044136.1", "url": "https://www.ensembl.org/id/ENSGALT00010044136.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026244.1", "url": "https://www.ensembl.org/id/ENSGALP00010026244.1" } ] } }, { "isoform_ac": "A0A8V0Z5M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535/entry#A0A8V0Z5M0-1", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSVFHIAQKRLIACFQGQYGTDPDKRHKKLPLTALAQNMQEGSAQLSDETLLGKMLDTCGDAENKLALELSQHEVQIEKDILEPLNTLTEVEIPNIQKQRKQLAKLVLDWDSARGRYNQAHKTSGTNFQMHPSKIDSLKEEMDEAGNKVEQCKDQLAADMYNFVSKEGEYAKFFVMLLEAQADYHRKALAVIEKVLPEIQAHQDKWTEKPAFGTPLEEHLKRSGREIAIPIEACVMMLLETGMREEGLFRIAAGASKLKKLKAALDCSTSQLDEFYSDPHAVAGALKSYLRELPEPLMTYALYEEWTQAANIQDQDKKLQELWKICNKLPKHYHANFRYLIKFLAKLAQNSDVNKMTPSNVAIVLGPNLLWAKTEGSLAEMAAATSVHVVAIIEPIIQHADWFFPGDQDFNVSGAFVAVPAVNSNHLSHTGNEYDSGTLERKRPVSMAVMEGDLLKKESFGVKVMDFQANPRRCGTINRKHTSPAFQPPLPPTEAGVLAHSGVEQHSQAAVAETSPVGAGFALSAGTAEQLQSQGNEDVSTSKPKDSTSSATPPPMRNGGHVSTAPNQSASSTNQLSVNQPQNAAGPSPHSMRRAVKKPAPAPPKPANPPPGQPGSQSSAPAAQPPSISPKPLARSSSPPAQHANQGAAMTSSSQVSAPRRYSSSLSPIQAPSHPPPQPPTQATPPLQPKANNQASPSAPSSEHGPEQPCYTPPQTPTPPDTPPLGKHSTTSPPSQPQSSTQDTSQSHSPPHSGTLPRPRPVPKPRNRPSVPPPPHPPSQLAGDGIIANPTQTASKIVTGGDGYCE", "length": 845, "header": "tr|A0A8V0Z5M0-1|A0A8V0Z535_CHICK Computationally mapped isoform of Rho GTPase-activating protein 17 OS=Gallus gallus OX=9031 GN=ARHGAP17 PE=1 SV=1 CANONICAL=A0A8V0Z535-1" }, "locus": { "chromosome": "14", "start_pos": 6623634, "end_pos": 6589048, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044119.1", "url": "https://www.ensembl.org/id/ENSGALT00010044119.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026231.1", "url": "https://www.ensembl.org/id/ENSGALP00010026231.1" } ] } }, { "isoform_ac": "A0A8V0Z6M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535/entry#A0A8V0Z6M6-1", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSVFHIAQKRLIACFQGQYGTDPDKRHKKLPLTALAQNMQEGSAQLSDETLLGKMLDTCGDAENKLALELSQHEVQIEKDILEPLNTLTEVEIPNIQKQRKQLAKLVLDWDSARGRYNQAHKTSGTNFQMHPSKIDSLKEEMDEAGNKVEQCKDQLAADMYNFVSKEGEYAKFFVMLLEAQADYHRKALAVIEKVLPEIQAHQDKWTEKPAFGTPLEEHLKRSGREIAIPIEACVMMLLETGMREEGLFRIAAGASKLKKLKAALDCSTSQLDEFYSDPHAVAGALKSYLRELPEPLMTYALYEEWTQAANIQDQDKKLQELWKICNKLPKHYHANFRYLIKFLAKLAQNSDVNKMTPSNVAIVLGPNLLWAKTEGSLAEMAAATSVHVVAIIEPIIQHADWFFPGDQDFNVSGAFVAVPAVNSNHLSHTGNEYDSGTLERKRPVSMAVMEGDLLKKESTSKPKDSTSSATPPPMRNGGHVSTAPNQSASSTNQLSVNQPQNAAGPSPHSMRRAVKKPAPAPPKPANPPPGQPGSQSSAPAAQPPSISPKPLARSSSPPAQHANQGAAMTSSSQVSAPRRYSSSLSPIQAPSHPPPQPPTQATPPLQPKANNQASPSAPSSEHGPEQPCYTPPQTPTPPDTPPLGKHSTTSPPSQPQSSTQDTSQSHSPPHSGTLPRPRPVPKPRNRPSVPPPPHPPSQLAGDGIIANPTQTASKIVTGECILSYSVSPQGVEMKKMSVAMCNFKSTSNS", "length": 789, "header": "tr|A0A8V0Z6M6-1|A0A8V0Z535_CHICK Computationally mapped isoform of Rho GTPase-activating protein 17 OS=Gallus gallus OX=9031 GN=ARHGAP17 PE=1 SV=1 CANONICAL=A0A8V0Z535-1" }, "locus": { "chromosome": "14", "start_pos": 6623634, "end_pos": 6589920, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044113.1", "url": "https://www.ensembl.org/id/ENSGALT00010044113.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026225.1", "url": "https://www.ensembl.org/id/ENSGALP00010026225.1" } ] } }, { "isoform_ac": "A0A8V0ZCJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z535/entry#A0A8V0ZCJ8-1", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSVFHIAQKRLIACFQGQYGTDPDKRHKKLPLTALAQNMQEGSAQLSDETLLGKMLDTCGDAENKLALELSQHEVQIEKDILEPLNTLTEVEIPNIQKQRKQLAKLVLDWDSARGRYNQAHKTSGTNFQMHPSKIDSLKEEMDEAGNKVEQCKDQLAADMYNFVSKEGEYAKFFVMLLEAQADYHRKALAVIEKVLPEIQAHQDKWTEKPAFGTPLEEHLKRSGREIAIPIEACVMMLLETGMREEGLFRIAAGASKLKKLKAALDCSTSQLDEFYSDPHAVAGALKSYLRELPEPLMTYALYEEWTQAANIQDQDKKLQELWKICNKLPKHYHANFRYLIKFLAKLAQNSDVNKMTPSNVAIVLGPNLLWAKTEGSLAEMAAATSVHVVAIIEPIIQHADWFFPGDQDFNVSGAFVAVPAVNSNHLSHTGNEYDSGTLERKRPVSMAVMEGDLLKKESFGVKVMDFQANPRRCGTINRKHTSPAFQPPLPPTEAGVLAHSGVEQHSQAAVAETSPVGAGFALSAGTAEQLQSQGNEDVSTSKPKDSTSSATPPPMRNGGHVSTAPNQSASSTNQLSVNQPQNAAGPSPHSMRRAVKKPAPAPPKPANPPPGQPGSQSSAPAAQPPSISPKPLARSSSPPAQHANQGAAMTSSSQVSAPRRYSSSLSPIQAPSHPPPQPPTQATPPLQPKANNQASPSAPSSEHGPEQPCYTPPQTPTPPDTPPLGKHSTTSPPSQPQSSTQDTSQSHSPPHSGTLPRPRPVPKPRNRPSVPPPPHPPSQLAGDGIIANPTQTASKIVTDV", "length": 840, "header": "tr|A0A8V0ZCJ8-1|A0A8V0Z535_CHICK Computationally mapped isoform of Rho GTPase-activating protein 17 OS=Gallus gallus OX=9031 GN=ARHGAP17 PE=1 SV=1 CANONICAL=A0A8V0Z535-1" }, "locus": { "chromosome": "14", "start_pos": 6623634, "end_pos": 6587123, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044128.1", "url": "https://www.ensembl.org/id/ENSGALT00010044128.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026238.1", "url": "https://www.ensembl.org/id/ENSGALP00010026238.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 591, "start_aa": "Thr", "end_pos": 591, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr591", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 723, "start_aa": "Thr", "end_pos": 723, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr723", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 757, "start_aa": "Thr", "end_pos": 757, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr757", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-GGA-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-GGA-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-GGA-9013404", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013404", "resource": "Reactome", "description": "RAC2 GTPase cycle" }, { "id": "R-GGA-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" }, { "id": "R-GGA-9013423", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-9013423", "resource": "Reactome", "description": "RAC3 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZZA8-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "ARHGAP17", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSATNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPHNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLATPTSNHSSHTGIDSVDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTLAPAGPEPPPQSSRAESSTGGGTVPSTAGMLEQGPSPGDSSPPKPKDSATAPAPGRNSSQAATGQSQAQAAAGSHQLSVGPAHNSAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGAQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPGATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQATPPPALAKPGSQGPAAPVALPGEHGLEQLSHTPPQTPTPPSTPPLGKQNPGGPPAAPTQAGSNTESAQPHAGTLPRPRPVPKPRNRPSMPPPPHPPGAHPTAADGSLSIAAPTASKIVTDANPRASEPLRSLFPEMHSDSASKDLPGRILLDMDNDTESTAL", "length": 883 }, "evidence": [ { "id": "A0A8V0Z535", "url": "https://omabrowser.org/oma/group/A0A8V0Z535/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1N458-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "ARHGAP17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLMACFQGQHGTDAERRHKKLPLTALAQNMLEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLAKLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFITLLEAQADYHRKALAVLEKALPELRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDINKMTPSNIAIVLGPNLLWAKNEGTLAEMAAATSVHVVAVIEPIIQHANWFFPEEVEFNVSEAFVPLTTPNSNHSSHTGNDPVDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHVSPAFQPPLPPTDGSTLAPAGPEPPPQSSRAESSTGGGTGPSSAGILEQGPSPGDSSPPKPKDSVAAPAPGRNSSQAAPGPSQAQAAAGSHQLSVGPAHNSAGPSPHTVRRAVKKPAPAPPKPGNPPPGHPGGQSSPGTSQHPPSLSPKPSTRSPSPPTQPPGQAPGQPCATSQLSAPRRYSSSLPPIQAPNHPPPQPPTQAASPSALTKPGSQGPPAPGEPGLEQSSHTPPQTPTPPSTPPLGKQNPGQAVSNPETAQPHAGTLPRPRPVPKPRNRPNVPPPPHPPGAHAAGDGNLSIAAPTASKIVTDANSRVSEPLRSIFPEMHSDSASKDLPGRILLDMDNDTESTAL", "length": 871 }, "evidence": [ { "id": "A0A8V0Z535", "url": "https://omabrowser.org/oma/group/A0A8V0Z535/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UIA2-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "Arhgap17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSMCHHSHKRLIACFQGQHGTDAERRHKKLPLTALAQNMQEASAQLEESLLGKMLETCGDAENQLALELSQHEVFVEKEIMDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKALPEMRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFSLYEEWTQVASVQDQDKKLQYLWTTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWAKQEGTLAEIAAATSVHVVAVIEPIIQHADWFFPGEVEFNVSEAFVPLATPNSNHSSHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHIAPAFQPPLPPTDGNALAPAGPEPPSQSSRADSSSGGGPVFSSTGILEQGLSPGDSSPPKPKDSVSAAVPAAGRNSNQMTTVPNQAQTGGNSHQLSVSTPHSAAGPSPHTLRRAVKKPAPAPPKPGNLPPGHPGGQSSPGTGTSPKPSARSPSPPQQQQQQQQQQQQQQQQQTPGMRRCSSSLPPIQAPSHPPPQPPTQPRLGEQGPEPGPTPPQTPTPPSTPPLAKQNPSQSETTQLHGTLPRPRPVPKPRNRPSVPPPPHPPGTHTVDGGLTSSVPTASRIVTDTNSRVSESLRSIFPEIHSDLASKEVPGHILLDIDNDTESTAL", "length": 846 }, "evidence": [ { "id": "A0A8V0Z535", "url": "https://omabrowser.org/oma/group/A0A8V0Z535/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54MV3-1", "protein_name": "Rho GTPase-activating protein gacJ", "gene_name": "gacJ", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEEQQPPSIKKKIVDFLTNFLKKRPSHEDLRRDNILVAPNNVSPAIQPSRYELEGHLNPSSHNRDDSSNNNNNNNNNNNTVEYSRGHSKSHSRSDSKHHNRENSKSDRDNSRSDNIRFGRKDTFKNAWDYLRNIDFTFSKTKYGNTVVHRLKHPQFGLSPEELQSLYPDQPHGIPIVLTKCFEYLSKHLETEGLFRVPGSNREVSLLKFKIEDGDLDFSEVLIPYNICGLISTFFKELPEPLIPFDYYNDAILITKLGSKDKYIIGLRDLVLSLPPANLCMLRKLLEFLLTVEKKNEFNKMTISNISIIFGVTLLKDPDTVDPMKSLNNIQAQSTIIKYMLEYFNDIFKEASVVKAYRKSIVPKEPMDTTSISYLDPAESNGGSPRTSNTPYQQQHQLSSQSMANIKPRPPSRSKMMRETIVLSPRVSGGNNQVYANATMTRPMSRLFFDPEIIPSPPPTTTTTTTTTTNTTTTTTTTNTTPNNTTTVNIQQKPVPPKPNLIPRKLPPNPNYSTYPAPLPPRQPNTIPLAPIPPPKPNSTYKKQITQPPPPRKPTSPSPPIATLKPTSKSDFIPSTNNNLNNNNTTTTTSSLISIPKAKPPPPKRNNVVSPAIEEPINPNLNINSTTTTPTPPLASFKNNGTISSGSKSNPNLQNLLNTNQPLVSSNGPPNKPPPQPFELLKSKPITTTPTIKKGVTFSETPKISNSPPSPSSSSPSPPHNQPIIVNKPIPSKSAPPPVRTTSSPSIVTKKFVPTIPTQTTTASSSSTPTTPKNQHLSKDDSSIPPINTSQTNNNISNSSIPSPKSKSALSLSTPKDSITGKPIKPPSNSDLSISTTPLPPTSSSPTSSSPLQSPKISSPSVLTVSQKIALNEKIAANQAKKNPLSNSGGLKQISPDLIKSNNINK", "length": 906 }, "evidence": [ { "id": "A0A8V0Z535", "url": "https://omabrowser.org/oma/group/A0A8V0Z535/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q68EM7-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "ARHGAP17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKKQFNRMKQLANQTVGRAEKTEVLSEDLLQIERRLDTVRSICHHSHKRLVACFQGQHGTDAERRHKKLPLTALAQNMQEASTQLEDSLLGKMLETCGDAENQLALELSQHEVFVEKEIVDPLYGIAEVEIPNIQKQRKQLARLVLDWDSVRARWNQAHKSSGTNFQGLPSKIDTLKEEMDEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAHQDKWAEKPAFGTPLEEHLKRSGREIALPIEACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLWARNEGTLAEMAAATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTASKIVTDSNSRVSEPHRSIFPEMHSDSASKDVPGRILLDIDNDTESTAL", "length": 881 }, "evidence": [ { "id": "A0A8V0Z535", "url": "https://omabrowser.org/oma/group/A0A8V0Z535/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N37-1", "protein_name": "Rho GTPase-activating protein 17", "gene_name": "Arhgap17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z563-1", "uniprot_ac": "A0A8V0Z563", "uniprot_id": "A0A8V0Z563_CHICK", "mass": { "chemical_mass": 64858.0, "monoisotopic_mass": 64858.0 }, "refseq": { "ac": "NP_001384212", "name": "leucine-rich repeat protein SHOC-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384212" }, "gene_names": [ { "name": "SHOC2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ] }, { "name": "SHOC2", "type": "synonym", "evidence": [ { "id": "NP_001384212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384212" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat protein SHOC-2", "type": "recommended", "evidence": [ { "id": "A0A8V0Z563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563/entry#names_and_taxonomy" } ] }, { "name": "Protein soc-2 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0Z563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat protein SHOC-2", "type": "synonym", "evidence": [ { "id": "NP_001384212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384212" } ] }, { "name": "protein Sur-8 homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0Z563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563/entry#names_and_taxonomy" } ] }, { "name": "protein soc-2 homolog", "type": "synonym", "evidence": [ { "id": "NP_001384212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384212" } ] }, { "name": "protein sur-8 homolog", "type": "synonym", "evidence": [ { "id": "NP_001384212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384212" } ] }, { "name": "soc-2 suppressor of clear homolog", "type": "synonym", "evidence": [ { "id": "NP_001384212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384212" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR13267654.203834.1, SRR13267661.21621.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992290, SAMEA103992323 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JAENSK010000232.1. On Nov 5, 2021 this sequence version replaced XP_015144138.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001384212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384212" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "SHOC2", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563", "locus": { "chromosome": "6", "start_pos": 27012627, "end_pos": 26956402, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010018299", "url": "https://www.ensembl.org/id/ENSGALG00010018299" } ] } } ], "crossref": [ { "id": "A0A8V0Z563", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z563", "database": "AlphaFoldDB", "categories": [] }, { "id": "423894", "url": "https://www.ncbi.nlm.nih.gov/gene/423894", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NQFTSYP", "url": "https://omabrowser.org/oma/group/NQFTSYP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z563", "url": "https://www.orthodb.org/?gene=A0A8V0Z563", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z5P7", "url": "https://www.orthodb.org/?gene=A0A8V0Z5P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-5673000", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673000", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001384212", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001384212", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z563-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5P7", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z5P7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSNLGKEKDCKEKDPKVPSSKEREKESKASGGFGKESKEKEPKTKGKDAKDGKKDSSSTQPGVAFSVDNTIKRPNPATGTRKKSSNAEVIKELNKCREENSMRLDLAKRSIHMLPSAVKELTQLTELYLYSNKLQSLPAEVGCLVNLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLTSLATLYLRFNRITTVEKDIKNLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPEEIGSCTQITNLDLQHNELLDLPETIGNLSSLSRLGLRYNRLSAIPKSLAKCSELDELNLENNNISTLPEGLLSSLVKLTSLTLARNCFQSYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "length": 582, "header": "tr|A0A8V0Z563-1|A0A8V0Z563_CHICK Isoform 1 of Leucine-rich repeat protein SHOC-2 OS=Gallus gallus OX=9031 GN=SHOC2 PE=3 SV=1 CANONICAL=A0A8V0Z563-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z563-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563/entry#A0A8V0Z563-1", "sequence": { "sequence": "MSSNLGKEKDCKEKDPKVPSSKEREKESKASGGFGKESKEKEPKTKGKDAKDGKKDSSSTQPGVAFSVDNTIKRPNPATGTRKKSSNAEVIKELNKCREENSMRLDLAKRSIHMLPSAVKELTQLTELYLYSNKLQSLPAEVGCLVNLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLTSLATLYLRFNRITTVEKDIKNLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPEEIGSCTQITNLDLQHNELLDLPETIGNLSSLSRLGLRYNRLSAIPKSLAKCSELDELNLENNNISTLPEGLLSSLVKLTSLTLARNCFQSYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "length": 582, "header": "tr|A0A8V0Z563-1|A0A8V0Z563_CHICK Isoform 1 of Leucine-rich repeat protein SHOC-2 OS=Gallus gallus OX=9031 GN=SHOC2 PE=3 SV=1 CANONICAL=A0A8V0Z563-1" }, "locus": { "chromosome": "6", "start_pos": 27011358, "end_pos": 26979043, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044166.1", "url": "https://www.ensembl.org/id/ENSGALT00010044166.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026264.1", "url": "https://www.ensembl.org/id/ENSGALP00010026264.1" } ] } }, { "isoform_ac": "A0A8V0Z5P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563/entry#A0A8V0Z5P7-1", "sequence": { "sequence": "MSSNLGKEKDCKEKDPKVPSSKEREKESKASGGFGKESKEKEPKTKGKDAKDGKKDSSSTQPGVAFSVDNTIKRPNPATGTRKKSSNAEVIKELNKCREENSMRLDLAKRSIHMLPSAVKELTQLTELYLYSNKLQSLPAEVGCLVNLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLTSLATLYLRFNRITTVEKDIKNLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPEEIGSCTQITNLDLQHNELLDLPETIGNLSSLSRLGLRYNRLSAIPKSLAKCSELDELNLENNNISTLPEGLLSSLVKLTSLTLARNCFQSYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGKILFFFFFNVSFLFV", "length": 529, "header": "tr|A0A8V0Z5P7-1|A0A8V0Z563_CHICK Computationally mapped isoform of Leucine-rich repeat protein SHOC-2 OS=Gallus gallus OX=9031 GN=SHOC2 PE=3 SV=1 CANONICAL=A0A8V0Z563-1" }, "locus": { "chromosome": "6", "start_pos": 27009837, "end_pos": 26979043, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044156.1", "url": "https://www.ensembl.org/id/ENSGALT00010044156.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026256.1", "url": "https://www.ensembl.org/id/ENSGALP00010026256.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-GGA-5673000", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-5673000", "resource": "Reactome", "description": "RAF activation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B795-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "SHOC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "length": 582 }, "evidence": [ { "id": "A0A8V0Z563", "url": "https://omabrowser.org/oma/group/A0A8V0Z563/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6QLV3-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "SHOC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSSSLGKEKDSKEKDPKAPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "length": 582 }, "evidence": [ { "id": "A0A8V0Z563", "url": "https://omabrowser.org/oma/group/A0A8V0Z563/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3I6S5-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "Shoc2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSLGKEKDSKEKDPKGPSAKEREKEAKASGGFGKESKEKDPKPKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVMKELNRCREENSARLDLSKRSIHALPPSVKELTQLTELYLYSNKLQSLPAELGCLLNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPPVVYRLDSLTTLYLRFNRITAVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "length": 582 }, "evidence": [ { "id": "A0A8V0Z563", "url": "https://omabrowser.org/oma/group/A0A8V0Z563/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O88520-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "Shoc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSSLGKEKDSKEKDPKVPSAKEREKESKASGGFGKESKEKEPKAKGKDAKDGKKESSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLPKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLSTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "length": 582 }, "evidence": [ { "id": "A0A8V0Z563", "url": "https://omabrowser.org/oma/group/A0A8V0Z563/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1L8Y7-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "shoc2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSTLGKDKDSKEREPKAEGKSKTKGKDAKDGKKDTSGASPAVAFTLDSTIKRPNPPPSTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHLLPSSIKELTQLTELYLYSNKLQSLPPEVGCLSGLVTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPAVVYRVSSLTTLYLRFNRITTVEKDIKNLSKLTMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNDLLDLPETIGNLASINRLGLRYNRLSAIPRSLAKCRELEELNLENNNISVLPEGLLSSLVNLTSLTLARNCFQSYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDICGLVSLEMLTLSNNLLKKLPYGIGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTYLGLGENLLQHLPEEIGTLENLEDLYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "length": 561 }, "evidence": [ { "id": "A0A8V0Z563", "url": "https://omabrowser.org/oma/group/A0A8V0Z563/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q54AX5-1", "protein_name": "Leucine-rich repeat protein lrrA", "gene_name": "lrrA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGGNLSSELKSTKYRKREIVDLRKMNIDKLPPTIGALQCKELLLSENDLITIPEEIGKLSKVEIIDFAKNRINYIPPEIGSLATLKQLFLSNNKLFYTPITPNIGALKNLTRLDLSSNQLDDLPVEISNCEALEYLDISDNQLQSFPLEFGKLYNLQVFNCSKNSLKSLPSEISGWVKLEELNVSNNQLAFLPNQICLLGLLSTLNVGFNKLQQLPEELSSMVSLTNLDLKVNPPLQYVPQLSNLRQLKILSIRNLQITHLPLGLGLLSELIELDIRDNPQLKEIPYDIATLINLQKLDLFGNNMRIVPREVGNLINLQTLDLRQNKLTIDNIPSEIGKLVNLKKLLLSNNLLIALPPEIASMKALKEFEASNNQLQAIPTEIGELSGLTKINLSGNKLTSIPASFGNLSELQICDLKSNEIAELPTTLDGLKSCTKIDLSHNMLTELPWEFGDLIGLTILDVGHNPLTIPPNPIVMKGTESIIQWLKKNEKEGRKGKVSGLGIQQDNEK", "length": 510 }, "evidence": [ { "id": "A0A8V0Z563", "url": "https://omabrowser.org/oma/group/A0A8V0Z563/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6AYI5-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "Shoc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKESSAAQPGVAFSVDNTIKRPNPALGTRKKSSNAEVTKELNKCREENSMRLDLSKRSIHILPPSVKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITAVEKDVRNLPRLSTLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLNRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "length": 582 }, "evidence": [ { "id": "A0A8V0Z563", "url": "https://omabrowser.org/oma/group/A0A8V0Z563/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UQ13-1", "protein_name": "Leucine-rich repeat protein SHOC-2", "gene_name": "SHOC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV", "length": 582 }, "evidence": [ { "id": "A0A8V0Z563", "url": "https://omabrowser.org/oma/group/A0A8V0Z563/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VEK6-1", "protein_name": "Leucine-rich repeat protein soc-2 homolog", "gene_name": "Sur-8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNLCSSGATASTTSLSSTGQAERSGGVPGGGAEGGGGSGNSGGGGKTSNGSAEAPTLCFAGGSGTAGAIAGTEELSNANSPANGAGGATGSTGSGQQPTGSNGHSHLHNENNANMPPETRPKMVTVKHPESNKPKPTTKKSKPIQADQDVIKALQRCRDEGIKRLDLSKSSITVIPSTVKECVHLTELYLYSNKIGQLPPEIGCLVSLRNLALNENSLTSLPESLQNCSQLKVLDLRHNKLAEIPPVIYRLRSLTTLYLRFNRITAVADDLRQLVNLTMLSLRENKIRELGSAIGALVNLTTLDVSHNHLEHLPEDIGNCVNLSALDLQHNELLDIPDSIGNLKSLVRLGMRYNRLSSVPATLKNCKSMDEFNVEGNGITQLPDGMLASLSGLTTITLSRNQFASYPTGGPAQFTNVYSINLEHNRIDKIPYGIFSRAKGLTKLNMKENMLTALPLDIGTWVNMVELNLATNALQKLPDDIMNLQNLEILILSNNMLKKIPNTIGNLRKLRILDLEENRIEVLPHEIGLLHELQRLILQTNQITMLPRSIGHLGNLTHLSVSENNLQFLPEEIGSLESLENLYINQNPGLEKLPFELALCQNLKYLNIDKCPLSTIPPEIQAGGPSLVLQWLKMHSPYRQM", "length": 641 }, "evidence": [ { "id": "A0A8V0Z563", "url": "https://omabrowser.org/oma/group/A0A8V0Z563/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of Ras protein signal transduction", "id": "GO:0046579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046579", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ], "pmid": "" }, { "name": "regulation of MAPK cascade", "id": "GO:0043408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043408", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ], "pmid": "" }, { "name": "nerve growth factor signaling pathway", "id": "GO:0038180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038180", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ], "pmid": "" }, { "name": "cyclic-GMP-AMP transmembrane import across plasma membrane", "id": "GO:0140361", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140361", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "protein phosphatase type 1 complex", "id": "GO:0000164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000164", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase 1 binding", "id": "GO:0008157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008157", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z563", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z563", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z563" }, { "id": "PF23598", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disease resistance R13L4/SHOC-2-like LRR", "eco_id": "ECO_0000259", "start_pos": 209, "end_pos": 386, "start_aa": "Lys", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 495, "end_pos": 497 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z571-1", "uniprot_ac": "A0A8V0Z571", "uniprot_id": "A0A8V0Z571_CHICK", "mass": { "chemical_mass": 86870.0, "monoisotopic_mass": 86870.0 }, "refseq": {}, "gene_names": [], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8V0Z571", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z571/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z571", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z571" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z571", "locus": {} } ], "crossref": [ { "id": "IPR050938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37456:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37456:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z571", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z571", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z571-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z571-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0ZAZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZAZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESQSLWGPTSLWGHRPYGVPHPYEAPHPYGVPVPMGSHIPYGVAVYMGSHIPYGVPHPYGLTVCMGSHIPYGVAHPNGVPHPYGLTVYMGLHIPYGVAVPMGSHSPNGVPHPYGVAVPMGSHIPMGSHIPMGSQCIWGPTSLWGRSVYGVPHPYGVAVCMGSQSQWGPTSLWGRTSLWAHSVYGVTHPYGVTVPMGSHIPMRPHIPMESQSQWGPTVPMGLHIPYGVAHSLWGRTVPMGSHVPYGVAVCMGSHIPMGSHVPYGVPVPMGSHIPMGSQCIWGRTSLWGRTVPMGSHIPMGSHVPYGVAHPNGVAHPNGVARSLWGRTSQWGRTSQWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPNGVAHPYGVARSLWGRTSQWGRTSPWGRTFPMGSHIPMGSHIPMGSHIPMGSHIPYGVARSLWGRTSQWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPNGVARSLWGRTSQWGRTSPWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPNGVAHPNGVARSLWGCTSQWGRTSLWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPYGVAHPNGVAHPNGVARSLWGRTSQWGRTSLWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPYGVAHPNGVAHPYGVARSLWGRTFPMGSHIPMGSHVPYGVAHPNGVAHPHGVARSLWGRTSQWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPNGVARSLWGRTSLWGRTFPMGSHIPMGSHVPYGVPRPAARRRSAQSSPTMLSARSSPSRPSFSRSRSSSLSAARPICAVRSPKMERISE", "length": 809, "header": "tr|A0A8V0Z571-1|A0A8V0Z571_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z571-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z571-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z571/entry#A0A8V0Z571-1", "sequence": { "sequence": "MESQSLWGPTSLWGHRPYGVPHPYEAPHPYGVPVPMGSHIPYGVAVYMGSHIPYGVPHPYGLTVCMGSHIPYGVAHPNGVPHPYGLTVYMGLHIPYGVAVPMGSHSPNGVPHPYGVAVPMGSHIPMGSHIPMGSQCIWGPTSLWGRSVYGVPHPYGVAVCMGSQSQWGPTSLWGRTSLWAHSVYGVTHPYGVTVPMGSHIPMRPHIPMESQSQWGPTVPMGLHIPYGVAHSLWGRTVPMGSHVPYGVAVCMGSHIPMGSHVPYGVPVPMGSHIPMGSQCIWGRTSLWGRTVPMGSHIPMGSHVPYGVAHPNGVAHPNGVARSLWGRTSQWGRTSQWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPNGVAHPYGVARSLWGRTSQWGRTSPWGRTFPMGSHIPMGSHIPMGSHIPMGSHIPYGVARSLWGRTSQWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPNGVARSLWGRTSQWGRTSPWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPNGVAHPNGVARSLWGCTSQWGRTSLWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPYGVAHPNGVAHPNGVARSLWGRTSQWGRTSLWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPYGVAHPNGVAHPYGVARSLWGRTFPMGSHIPMGSHVPYGVAHPNGVAHPHGVARSLWGRTSQWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPNGVARSLWGRTSLWGRTFPMGSHIPMGSHVPYGVPRPAARRRSAQSSPTMLSARSSPSRPSFSRSRSSSLSAARPICAVRSPKMERISE", "length": 809, "header": "tr|A0A8V0Z571-1|A0A8V0Z571_CHICK Isoform 1 of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z571-1" }, "locus": { "chromosome": "22", "start_pos": 1457856, "end_pos": 1455430, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048085.1", "url": "https://www.ensembl.org/id/ENSGALT00010048085.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028373.1", "url": "https://www.ensembl.org/id/ENSGALP00010028373.1" } ] } }, { "isoform_ac": "A0A8V0ZAZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z571/entry#A0A8V0ZAZ9-1", "sequence": { "sequence": "MESQSLWGPTSLWGHRPYGVPHPYEAPHPYGVPVPMGSHIPYGVAVYMGSHIPYGVPHPYGLTVCMGSHIPYGVAHPNGVPHPYGLTVYMGLHIPYGVAVPMGSHSPNGVPHPYGVAVPMGSHIPMGSHIPMGSQCIWGPTSLWGRSVYGVPHPYGVAVCMGSQSQWGPTSLWGRTSLWAHSVYGVTHPYGVTVPMGSHIPMRPHIPMESQSQWGPTVPMGLHIPYGVAHSLWGRTVPMGSHVPYGVAVCMGSHIPMGSHVPYGVPVPMGSHIPMGSQCIWGRTSLWGRTVPMGSHIPMGSHVPYGVAHPNGVAHPNGVARSLWGRTSQWGRTSQWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPNGVAHPYGVARSLWGRTSQWGRTSPWGRTFPMGSHIPMGSHIPMGSHIPMGSHVPYGVAHPYGVAHPNGVARSLWGRTSQWGRTSQWGRTFPMGLHIPMGSHIPMGSHVPYGVAHPNGVAHPHGVARSLWGRTSLWGRTSQWGRTSQWGRTFPMGSHIPMGSHIPMGSHVPYGVAHPNGVAHPHGVARSLWGRTSLWGRTSQWGRTSLWGRTFPMGSHVPYGVAHPNGVARSLWGRTSQWGRTSPWGRTFPMGSHIPMGSHVPYGVAHPNGVAHPHGVARSLWGRTSQWGRTFPMGSHIPMGSHVPYGVAHPYGVARSLRGAASRGAAPQRSVVSHNAERPQLSEPPLILALPQFVAERRAADLRREVPKDGAHLRVEHHLQGAPPPAAVRSMATAGAVCALWALPALYVPYGYCRPYMCPMGTAGPICALWALLAL", "length": 802, "header": "tr|A0A8V0ZAZ9-1|A0A8V0Z571_CHICK Computationally mapped isoform of Uncharacterized protein OS=Gallus gallus OX=9031 GN= PE=4 SV=1 CANONICAL=A0A8V0Z571-1" }, "locus": { "chromosome": "22", "start_pos": 1457856, "end_pos": 1455248, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048081.1", "url": "https://www.ensembl.org/id/ENSGALT00010048081.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028372.1", "url": "https://www.ensembl.org/id/ENSGALP00010028372.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 217, "start_aa": "Thr", "end_pos": 217, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr217", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 217 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z576-1", "uniprot_ac": "A0A8V0Z576", "uniprot_id": "A0A8V0Z576_CHICK", "mass": { "chemical_mass": 91348.0, "monoisotopic_mass": 91348.0 }, "refseq": {}, "gene_names": [ { "name": "NOC3L", "type": "recommended", "evidence": [ { "id": "A0A8V0Z576", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576" } ] } ], "protein_names": [ { "name": "Nucleolar complex protein 3 homolog", "type": "recommended", "evidence": [ { "id": "A0A8V0Z576", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576/entry#names_and_taxonomy" } ] }, { "name": "NOC3 protein homolog", "type": "synonym", "evidence": [ { "id": "A0A8V0Z576", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z576", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "NOC3L", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576", "locus": { "chromosome": "6", "start_pos": 20909897, "end_pos": 20891602, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010019916", "url": "https://www.ensembl.org/id/ENSGALG00010019916" } ] } } ], "crossref": [ { "id": "A0A8V0Z576", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z576", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR005612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z576", "url": "https://www.orthodb.org/?gene=A0A8V0Z576", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14428:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14428:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03914", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03914", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07540", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07540", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z576", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z576-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPRKNTKRVPSFRKLLRTSKIKLDNKLKNKQYKQQSAAKKYRKEQKKLRQAVRDAVCKKPFPLEDYKKKHVAEKQEEEEEDEALPLDMMDEDDLKLMEDLARKASFLTRDISSNEPVHIKKRKRDSVIEKYEKIPRRINAEPEKELIHLLPIKDKGGIIPQTMEKPVPDVAEDEEEDMEEMEVAEELNEEPPPVLTPEEMAAQRKVKLQERKMHIAALASAILSDPENNIKKLKELRAMLMEQDPNVAVIVRKLVMVSLMEVFKDIAPSYKIRPLTEAEKATKVKKETQKLREFEEGLVSQYKFYLENLEQTIKDWKQRKLKKSNVVSLKAYKGLAEIAVKCLCELLVALPHFNFHNNIIVLIVPLMNDASKTISELCCEAVKKLFKQDKLGFASLGVVKVVSGLVKGRNYNVRPEVLKVFLHLRIKEVELKKDSEDIAPKKKFMTFKEKRKHLSRMQRKWKKAEEKLERELLEAEASESKEKKLKLHTETLNIVFLTYFRILKRAQKSPLLPAVLEGLAKFAHLINVEFFDDLLIVLHSLISSDDLSYRESLHCILSAFQILSGQGDVLNIDPMKFYTHLYKTLFSLHAGGTNDDIGIVLQCLDVMLAKRRKQVSQQRALAFMKRLSTLALHVLPHSSIGILATNRILMQTFPKMDLLLDNESQGSGVYLPELDEPEHCNAQNTALWELHLLQPTVQKFAAHLAVGAPAEGSGALSLDLSRRPATELFEAYNMKGMTFNPPVPSVTPRRKDTFSHVDSFLNQELTEQLQQHMSKTVSHKSLDFARHLQESSLS", "length": 795, "header": "tr|A0A8V0Z576-1|A0A8V0Z576_CHICK Isoform 1 of Nucleolar complex protein 3 homolog OS=Gallus gallus OX=9031 GN=NOC3L PE=1 SV=1 CANONICAL=A0A8V0Z576-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z576-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576/entry#A0A8V0Z576-1", "sequence": { "sequence": "MKPRKNTKRVPSFRKLLRTSKIKLDNKLKNKQYKQQSAAKKYRKEQKKLRQAVRDAVCKKPFPLEDYKKKHVAEKQEEEEEDEALPLDMMDEDDLKLMEDLARKASFLTRDISSNEPVHIKKRKRDSVIEKYEKIPRRINAEPEKELIHLLPIKDKGGIIPQTMEKPVPDVAEDEEEDMEEMEVAEELNEEPPPVLTPEEMAAQRKVKLQERKMHIAALASAILSDPENNIKKLKELRAMLMEQDPNVAVIVRKLVMVSLMEVFKDIAPSYKIRPLTEAEKATKVKKETQKLREFEEGLVSQYKFYLENLEQTIKDWKQRKLKKSNVVSLKAYKGLAEIAVKCLCELLVALPHFNFHNNIIVLIVPLMNDASKTISELCCEAVKKLFKQDKLGFASLGVVKVVSGLVKGRNYNVRPEVLKVFLHLRIKEVELKKDSEDIAPKKKFMTFKEKRKHLSRMQRKWKKAEEKLERELLEAEASESKEKKLKLHTETLNIVFLTYFRILKRAQKSPLLPAVLEGLAKFAHLINVEFFDDLLIVLHSLISSDDLSYRESLHCILSAFQILSGQGDVLNIDPMKFYTHLYKTLFSLHAGGTNDDIGIVLQCLDVMLAKRRKQVSQQRALAFMKRLSTLALHVLPHSSIGILATNRILMQTFPKMDLLLDNESQGSGVYLPELDEPEHCNAQNTALWELHLLQPTVQKFAAHLAVGAPAEGSGALSLDLSRRPATELFEAYNMKGMTFNPPVPSVTPRRKDTFSHVDSFLNQELTEQLQQHMSKTVSHKSLDFARHLQESSLS", "length": 795, "header": "tr|A0A8V0Z576-1|A0A8V0Z576_CHICK Isoform 1 of Nucleolar complex protein 3 homolog OS=Gallus gallus OX=9031 GN=NOC3L PE=1 SV=1 CANONICAL=A0A8V0Z576-1" }, "locus": { "chromosome": "6", "start_pos": 20907606, "end_pos": 20891640, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048104.1", "url": "https://www.ensembl.org/id/ENSGALT00010048104.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028385.1", "url": "https://www.ensembl.org/id/ENSGALP00010028385.1" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 748, "start_aa": "Thr", "end_pos": 748, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr748", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z576", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z576", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z576", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA replication initiation", "id": "GO:0006270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006270", "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z576", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 663, "end_pos": 665, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z576", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576" }, { "id": "PF03914", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03914" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCAAT-binding factor", "eco_id": "ECO_0000259", "start_pos": 553, "end_pos": 700, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8V0Z576", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z576" }, { "id": "PF07540", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07540" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleolar complex-associated protein 3 N-terminal", "eco_id": "ECO_0000259", "start_pos": 212, "end_pos": 306, "start_aa": "Arg", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 748 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 663, "end_pos": 665 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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{ "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", 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"end_pos": 22911969, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010044195.1", "url": "https://www.ensembl.org/id/ENSGALT00010044195.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010026285.1", "url": "https://www.ensembl.org/id/ENSGALP00010026285.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8V0Z590-1", "uniprot_ac": "A0A8V0Z590", "uniprot_id": "A0A8V0Z590_CHICK", "mass": { "chemical_mass": 87156.0, "monoisotopic_mass": 87156.0 }, "refseq": {}, "gene_names": [ { "name": "LOC107051325", "type": "recommended", "evidence": [ { "id": "A0A8V0Z590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z590" } ] } ], "protein_names": [ { "name": "DUF4657 domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8V0Z590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z590/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A8V0Z590", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z590" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "LOC107051325", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z590", "locus": {} } ], "crossref": [ { "id": "A0A8V0Z590", "url": "https://alphafold.ebi.ac.uk/entry/A0A8V0Z590", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR009091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8V0Z590", "url": "https://www.orthodb.org/?gene=A0A8V0Z590", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31294", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31294", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31294:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31294:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15552", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15552", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0A8V0Z590", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z590", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z590-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z590-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGANGAVWKRRFSCYAPHEAQCCTAPPPRSVYRRLHDDPRGDPTSGAPPPKPQSEDPREEMGGAETSPRPVCGVTAGRPQKGRGAETPRSRSCIRRQRRRGGAGGDPKDCGGGDPKTRGDGNPEERGNGDPINCAIGDPKAHGIWVPRKRDIGDPKDCGNGDPINCAIGDPKTCAIGDPKAHGIWVPRKNGIEDPKDCGNGDPINCAMGDPKECGNGDPINCAMGDPKAHGIWVPRECGIGDPKDCGNGDPKDCAIGDPKTCAIGDPINCAIGDLEECGNGDPINCAMGDPKAHGIWVPRERGIGDPKDCGNGDPKNCAMGDPKQCRIGVPKECGERDPKEHWNGVPKGRAIWDPKSCAIGNPKSCAIVDIKSCPTGDPQSYATGGPKSCTIGDSKSCAIGNPKSCATRDPKSCPIGNPKSFTIGDPKSCAIGDPQSCAIGNPKSCTSGDPQNYVTGFPKSCAIGNPKSCTTGDPKSCAIGDPQSFAIGFPKSCAIGDPKSCAIGNPKSCAIGDPKICTIGEPQSYATGFPKSCAIENPKNCATGDPKSCAIGNPQSYAIGFPKSCAIGDPKICTTGDPQSCAIGDRQSCAIGNPKSCAIGDPQSCATGDPKSCAIGDPQSCAIGDPKNRTIGDPQSCAIGFPKSCAIGNPKSCAIGDPQSCAIGDPKSCATGDRQSYAIGFPKSCAIGNPKSCAIGDPQSCAVAAAPPAAGLRYLELICRTMERVARLQEDNRRLRQWGGAARAGGGPGSLRAPQRPPTDGGGDLGTGRAERFRTRSCSDSRVAAHSPTRQWGHSVSSPTLLDPTEPPPAPHKDGRSHWGRVKVLLNRFTRRSLRGR", "length": 839, "header": "tr|A0A8V0Z590-1|A0A8V0Z590_CHICK Isoform 1 of DUF4657 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107051325 PE=4 SV=1 CANONICAL=A0A8V0Z590-1" }, "isoforms": [ { "isoform_ac": "A0A8V0Z590-1", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z590/entry#A0A8V0Z590-1", "sequence": { "sequence": "MWGANGAVWKRRFSCYAPHEAQCCTAPPPRSVYRRLHDDPRGDPTSGAPPPKPQSEDPREEMGGAETSPRPVCGVTAGRPQKGRGAETPRSRSCIRRQRRRGGAGGDPKDCGGGDPKTRGDGNPEERGNGDPINCAIGDPKAHGIWVPRKRDIGDPKDCGNGDPINCAIGDPKTCAIGDPKAHGIWVPRKNGIEDPKDCGNGDPINCAMGDPKECGNGDPINCAMGDPKAHGIWVPRECGIGDPKDCGNGDPKDCAIGDPKTCAIGDPINCAIGDLEECGNGDPINCAMGDPKAHGIWVPRERGIGDPKDCGNGDPKNCAMGDPKQCRIGVPKECGERDPKEHWNGVPKGRAIWDPKSCAIGNPKSCAIVDIKSCPTGDPQSYATGGPKSCTIGDSKSCAIGNPKSCATRDPKSCPIGNPKSFTIGDPKSCAIGDPQSCAIGNPKSCTSGDPQNYVTGFPKSCAIGNPKSCTTGDPKSCAIGDPQSFAIGFPKSCAIGDPKSCAIGNPKSCAIGDPKICTIGEPQSYATGFPKSCAIENPKNCATGDPKSCAIGNPQSYAIGFPKSCAIGDPKICTTGDPQSCAIGDRQSCAIGNPKSCAIGDPQSCATGDPKSCAIGDPQSCAIGDPKNRTIGDPQSCAIGFPKSCAIGNPKSCAIGDPQSCAIGDPKSCATGDRQSYAIGFPKSCAIGNPKSCAIGDPQSCAVAAAPPAAGLRYLELICRTMERVARLQEDNRRLRQWGGAARAGGGPGSLRAPQRPPTDGGGDLGTGRAERFRTRSCSDSRVAAHSPTRQWGHSVSSPTLLDPTEPPPAPHKDGRSHWGRVKVLLNRFTRRSLRGR", "length": 839, "header": "tr|A0A8V0Z590-1|A0A8V0Z590_CHICK Isoform 1 of DUF4657 domain-containing protein OS=Gallus gallus OX=9031 GN=LOC107051325 PE=4 SV=1 CANONICAL=A0A8V0Z590-1" }, "locus": { "chromosome": "22", "start_pos": 1463870, "end_pos": 1459308, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010048135.1", "url": "https://www.ensembl.org/id/ENSGALT00010048135.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010028400.1", "url": "https://www.ensembl.org/id/ENSGALP00010028400.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8V0Z590", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8V0Z590" }, { "id": "PF15552", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15552" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4657", "eco_id": "ECO_0000259", "start_pos": 697, "end_pos": 837, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 630, "end_pos": 632 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0I564-1", "uniprot_ac": "B0I564", "uniprot_id": "FANCI_CHICK", "mass": { "chemical_mass": 149289.0, "monoisotopic_mass": 149289.0 }, "refseq": { "ac": "NP_001108323", "name": "Fanconi anemia group I protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323" }, "gene_names": [ { "name": "FANCI", "type": "recommended", "evidence": [ { "id": "B0I564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0I564" } ] }, { "name": "FANCI", "type": "synonym", "evidence": [ { "id": "NP_001108323", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323" } ] } ], "protein_names": [ { "name": "Fanconi anemia group I protein", "type": "recommended", "evidence": [ { "id": "B0I564", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0I564/entry#names_and_taxonomy" } ] }, { "name": "Fanconi anemia group I protein", "type": "synonym", "evidence": [ { "id": "NP_001108323", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: AB378696.1, SRR13267655.78831.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA103992290, SAMEA103992323 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000245.1. On Sep 23, 2021 this sequence version replaced NP_001108323.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001108323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323" } ] }, { "annotation": "Collectively, the FANCI-FANCD2 complex-mediated stabilization of the RAD51 nucleoprotein filament may function to prevent destructive DNA degradation by exonucleases during replication and at stalled replication forks.", "evidence": [ { "database": "RefSeq", "id": "NP_001108323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323" }, { "database": "PubMed", "id": "27694619", "url": "https://glygen.org/publication/PubMed/27694619" } ] }, { "annotation": "FANCD2 possesses nucleosome-assembly activity in vitro and FANCD2-FANCI may regulate chromatin dynamics during DNA repair", "evidence": [ { "database": "RefSeq", "id": "NP_001108323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323" }, { "database": "PubMed", "id": "22828868", "url": "https://glygen.org/publication/PubMed/22828868" } ] }, { "annotation": "FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.", "evidence": [ { "database": "RefSeq", "id": "NP_001108323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323" }, { "database": "PubMed", "id": "32066963", "url": "https://glygen.org/publication/PubMed/32066963" } ] }, { "annotation": "Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair of interstrand DNA cross-links (ICLs) by promoting FANCD2 monoubiquitination by FANCL and participating in recruitment to DNA repair sites (By similarity). The FANCI-FANCD2 complex binds and scans double-stranded DNA (dsDNA) for DNA damage; this complex stalls at DNA junctions between double-stranded DNA and single-stranded DNA (PubMed:32066963, PubMed:36050501, PubMed:39085614). Participates in S phase and G2 phase checkpoint activation upon DNA damage (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564#function" }, { "database": "PubMed", "id": "32066963", "url": "https://glygen.org/publication/PubMed/32066963" }, { "database": "PubMed", "id": "39085614", "url": "https://glygen.org/publication/PubMed/39085614" }, { "database": "PubMed", "id": "36050501", "url": "https://glygen.org/publication/PubMed/36050501" }, { "database": "UniProtKB", "id": "Q9NVI1", "url": "https://www.uniprot.org/uniprotkb/Q9NVI1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [ { "start_pos": 558, "end_pos": 558, "sequence_org": "S", "sequence_mut": "D", "comment": "Phosphomimetic mutation that promotes ubiquitination on FANCD2; when associated with D-561 and D-567.", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" }, { "database": "PubMed", "id": "36050501", "url": "https://glygen.org/publication/PubMed/36050501" } ] }, { "start_pos": 561, "end_pos": 561, "sequence_org": "S", "sequence_mut": "D", "comment": "Phosphomimetic mutation that promotes ubiquitination on FANCD2; when associated with D-558 and D-567.", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" }, { "database": "PubMed", "id": "36050501", "url": "https://glygen.org/publication/PubMed/36050501" } ] }, { "start_pos": 567, "end_pos": 567, "sequence_org": "T", "sequence_mut": "D", "comment": "Phosphomimetic mutation that promotes ubiquitination on FANCD2; when associated with D-558 and D-561.", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" }, { "database": "PubMed", "id": "36050501", "url": "https://glygen.org/publication/PubMed/36050501" } ] } ], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FANCI", "url": "https://www.uniprot.org/uniprotkb/B0I564", "locus": { "chromosome": "10", "start_pos": 12964867, "end_pos": 12988651, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010016181", "url": "https://www.ensembl.org/id/ENSGALG00010016181" } ] } } ], "crossref": [ { "id": "B0I564", "url": "https://alphafold.ebi.ac.uk/entry/B0I564", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11720", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11720", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "415491", "url": "https://www.ncbi.nlm.nih.gov/gene/415491", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "6TNF", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6TNF&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "6TNG", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=6TNG&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "8A2Q", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=8A2Q&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9FFB", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9FFB&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "9FFF", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?mmdbid=9FFF&bu=0", "database": "iCn3D", "categories": [ "3D Structure" ] }, { "id": "B0I564", "url": "https://www.ebi.ac.uk/intact/interactors/id:B0I564*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR026171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:415491", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415491", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "B0I564", "url": "https://www.orthodb.org/?gene=B0I564", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21818:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21818:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "pdb_00006tnf", "url": "https://www.rcsb.org/structure/pdb_00006tnf", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00006tng", "url": "https://www.rcsb.org/structure/pdb_00006tng", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00008a2q", "url": "https://www.rcsb.org/structure/pdb_00008a2q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009ffb", "url": "https://www.rcsb.org/structure/pdb_00009ffb", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "pdb_00009fff", "url": "https://www.rcsb.org/structure/pdb_00009fff", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6TNF", "url": "https://www.rcsb.org/structure/6TNF", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6TNG", "url": "https://www.rcsb.org/structure/6TNG", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "8A2Q", "url": "https://www.rcsb.org/structure/8A2Q", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9FFB", "url": "https://www.rcsb.org/structure/9FFB", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "9FFF", "url": "https://www.rcsb.org/structure/9FFF", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF14674", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14674", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14675", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14675", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14676", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14676", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14678", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14678", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14680", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14680", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:B0I564", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:B0I564", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001108323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0I564-1", "url": "https://www.uniprot.org/uniprotkb/B0I564-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQRILQLAAEGSPERLQEALQGLTEGELGDMVTRQALRGRETAALLKGIFKGSPCSQQSGVLRRLQVYKHCVSLVESGDLHVGKVSEIIGLLMLEARQLPGHALAELATLFVEVIKRGSLSNGKSLELFSTVLTALSNSKESLAYGKGELNGEEFKKQLINTLCSSKWDPQCVIHLANMFRDIPLSGEELQFVVEKVLRMFSKLDLQEIPPLVYQLLLLSAKGSKKTVLEGIISFFNQLDKRQKEEQRVPQSADLEVATVPLDQLRHVEGTVILHIVSAINLDQDIGEELIKHLKTEQQKDPGKALCPFSVSLLLSTAVKHRLQEQIFDFLKTSITRSCKDLQILQASKFLQDLCPQQYDVTAVILEVVKNSAFGWDHVTQGLVDLGFSLMESYEPKKSFGGKAAETNLGLSKMPAQQACKLGASILLETFKVHEPIRSDILEQVLNRVLTKAASPVSHFIDLLSNIVVSAPLVLQNSSSRVTETFDNLSFLPIDTVQGLLRAVQPLLKVSMSVRDSLILVLQKAIFSRQLDARKAAVAGFLLLLRNFKILGSLTSSQCSQAIGATQVQADVHACYNSAANEAFCLEILGSLRRCLSQQADVRLMLYEGFYDVLRRNSQLASSIMETLLSQIKQYYLPQQDLLPPLKLEGCIMAQGDQIFLQEPLAHLLCCIQHCLAWYKSTVHLCKGAEDEEEEEDVGFEQNFEEMLESVTRRMIKSELEDFELDKSADFSPSSGVGVKNNIYAIQVMGICEVLIEYNFKIGNFSKNKFEDVLGLFTCYNKLSEILKEKAGKNKSTLGNRIARSFLSMGFVSTLLTALFRDNAQSHEESLAVLRSSTEFMRYAVSVALQKVQQLEEMGQTDGPDGQNPEKMFQNLCKITRVLLWRYTSIPTAVEESGKKKGKSISLLCLEGLLRIFNTMQQLYAARIPQFLQALDITDGDAEEADINVTEKAAFQIRQFQRSLVNQLSSAEDDFNSKETQLLITILSTLSKLLDPGSQQFLQFLTWTVKICKENALEDLSCCKGLLTLLFSLHVLYKSPVSLLRELAQDIHACLGDIDQDVEIESRSHFAIVNVKTAAPTVCLLVLGQADKVLEEVDWLIKRLTILGSDTSEDSTQASNQTQALEKGVILQLGTLLTVFHELVQTALPAGSCVDSLLRSLSKTYAILTSLIKHYIQACRSTSNTVPGRLEKLVKLSGSHLTPQCYSFITYVQNIHSESLSFAEEKKKKKKEDETAVVSTVMAKVLRDTKPIPNLIFAIEQYEKFLIHLSKKSKVNLMQYMKLSTSRDFRINASMLDSVLQEQNTEDAENEPDNNQSGTAEQPDENQEPQKKRRRKK", "length": 1338, "header": "sp|B0I564-1|FANCI_CHICK Isoform 1 of Fanconi anemia group I protein OS=Gallus gallus OX=9031 GN=FANCI PE=1 SV=1 CANONICAL=B0I564-1" }, "isoforms": [ { "isoform_ac": "B0I564-1", "url": "https://www.uniprot.org/uniprotkb/B0I564/entry#B0I564-1", "sequence": { "sequence": "MAQRILQLAAEGSPERLQEALQGLTEGELGDMVTRQALRGRETAALLKGIFKGSPCSQQSGVLRRLQVYKHCVSLVESGDLHVGKVSEIIGLLMLEARQLPGHALAELATLFVEVIKRGSLSNGKSLELFSTVLTALSNSKESLAYGKGELNGEEFKKQLINTLCSSKWDPQCVIHLANMFRDIPLSGEELQFVVEKVLRMFSKLDLQEIPPLVYQLLLLSAKGSKKTVLEGIISFFNQLDKRQKEEQRVPQSADLEVATVPLDQLRHVEGTVILHIVSAINLDQDIGEELIKHLKTEQQKDPGKALCPFSVSLLLSTAVKHRLQEQIFDFLKTSITRSCKDLQILQASKFLQDLCPQQYDVTAVILEVVKNSAFGWDHVTQGLVDLGFSLMESYEPKKSFGGKAAETNLGLSKMPAQQACKLGASILLETFKVHEPIRSDILEQVLNRVLTKAASPVSHFIDLLSNIVVSAPLVLQNSSSRVTETFDNLSFLPIDTVQGLLRAVQPLLKVSMSVRDSLILVLQKAIFSRQLDARKAAVAGFLLLLRNFKILGSLTSSQCSQAIGATQVQADVHACYNSAANEAFCLEILGSLRRCLSQQADVRLMLYEGFYDVLRRNSQLASSIMETLLSQIKQYYLPQQDLLPPLKLEGCIMAQGDQIFLQEPLAHLLCCIQHCLAWYKSTVHLCKGAEDEEEEEDVGFEQNFEEMLESVTRRMIKSELEDFELDKSADFSPSSGVGVKNNIYAIQVMGICEVLIEYNFKIGNFSKNKFEDVLGLFTCYNKLSEILKEKAGKNKSTLGNRIARSFLSMGFVSTLLTALFRDNAQSHEESLAVLRSSTEFMRYAVSVALQKVQQLEEMGQTDGPDGQNPEKMFQNLCKITRVLLWRYTSIPTAVEESGKKKGKSISLLCLEGLLRIFNTMQQLYAARIPQFLQALDITDGDAEEADINVTEKAAFQIRQFQRSLVNQLSSAEDDFNSKETQLLITILSTLSKLLDPGSQQFLQFLTWTVKICKENALEDLSCCKGLLTLLFSLHVLYKSPVSLLRELAQDIHACLGDIDQDVEIESRSHFAIVNVKTAAPTVCLLVLGQADKVLEEVDWLIKRLTILGSDTSEDSTQASNQTQALEKGVILQLGTLLTVFHELVQTALPAGSCVDSLLRSLSKTYAILTSLIKHYIQACRSTSNTVPGRLEKLVKLSGSHLTPQCYSFITYVQNIHSESLSFAEEKKKKKKEDETAVVSTVMAKVLRDTKPIPNLIFAIEQYEKFLIHLSKKSKVNLMQYMKLSTSRDFRINASMLDSVLQEQNTEDAENEPDNNQSGTAEQPDENQEPQKKRRRKK", "length": 1338, "header": "sp|B0I564-1|FANCI_CHICK Isoform 1 of Fanconi anemia group I protein OS=Gallus gallus OX=9031 GN=FANCI PE=1 SV=1 CANONICAL=B0I564-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 558, "end_pos": 558, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" }, { "database": "PubMed", "id": "36050501", "url": "https://glygen.org/publication/PubMed/36050501" } ], "site_lbl": "Ser558" }, { "start_pos": 561, "end_pos": 561, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" }, { "database": "PubMed", "id": "36050501", "url": "https://glygen.org/publication/PubMed/36050501" } ], "site_lbl": "Ser561" }, { "start_pos": 567, "end_pos": 567, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" }, { "database": "PubMed", "id": "36050501", "url": "https://glygen.org/publication/PubMed/36050501" } ], "site_lbl": "Thr567" } ], "glycation": [], "keywords": [], "publication": [ { "title": "Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.", "journal": "Molecular cell", "date": "2001", "authors": "Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C, Hejna J, Grompe M, D'Andrea AD", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "11239454", "url": "https://glygen.org/publication/PubMed/11239454" } ] }, { "title": "Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways.", "journal": "Cell", "date": "2002", "authors": "Taniguchi T, Garcia-Higuera I, Xu B, Andreassen PR, Gregory RC, Kim ST, Lane WS, Kastan MB, D'Andrea AD", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "12086603", "url": "https://glygen.org/publication/PubMed/12086603" } ] }, { "title": "Insights into DNA recombination from the structure of a RAD51-BRCA2 complex.", "journal": "Nature", "date": "2002", "authors": "Pellegrini L, Yu DS, Lo T, Anand S, Lee M, Blundell TL, Venkitaraman AR", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "12442171", "url": "https://glygen.org/publication/PubMed/12442171" } ] }, { "title": "The BRIP1 helicase functions independently of BRCA1 in the Fanconi anemia pathway for DNA crosslink repair.", "journal": "Nature genetics", "date": "2005", "authors": "Bridge WL, Vandenberg CJ, Franklin RJ, Hiom K", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "16116421", "url": "https://glygen.org/publication/PubMed/16116421" } ] }, { "title": "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.", "journal": "Cell", "date": "2007", "authors": "Smogorzewska A, Matsuoka S, Vinciguerra P, McDonald ER 3rd, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K, D'Andrea AD, Elledge SJ", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "17412408", "url": "https://glygen.org/publication/PubMed/17412408" } ] }, { "title": "Identification of the Fanconi anemia complementation group I gene, FANCI.", "journal": "Cellular oncology : the official journal of the International Society for Cellular Oncology", "date": "2007", "authors": "Dorsman JC, Levitus M, Rockx D, Rooimans MA, Oostra AB, Haitjema A, Bakker ST, Steltenpool J, Schuler D, Mohan S, Schindler D, Arwert F, Pals G, Mathew CG, Waisfisz Q, de Winter JP, Joenje H", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "17452773", "url": "https://glygen.org/publication/PubMed/17452773" } ] }, { "title": "FANCI is a second monoubiquitinated member of the Fanconi anemia pathway.", "journal": "Nature structural & molecular biology", "date": "2007", "authors": "Sims AE, Spiteri E, Sims RJ 3rd, Arita AG, Lach FP, Landers T, Wurm M, Freund M, Neveling K, Hanenberg H, Auerbach AD, Huang TT", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "17460694", "url": "https://glygen.org/publication/PubMed/17460694" } ] }, { "title": "Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair.", "journal": "The EMBO journal", "date": "2012-08-29", "authors": "Sato Koichi, Ishiai Masamichi, Toda Kazue, Furukoshi Satoshi, Osakabe Akihisa, Tachiwana Hiroaki, Takizawa Yoshimasa, Kagawa Wataru, Kitao Hiroyuki, Dohmae Naoshi, Obuse Chikashi, Kimura Hiroshi, Takata Minoru, Kurumizaka Hitoshi", "evidence": [ { "database": "RefSeq", "id": "NP_001108323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323" } ], "reference": [ { "type": "PubMed", "id": "22828868", "url": "https://glygen.org/publication/PubMed/22828868" } ] }, { "title": "FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5'-DNA end.", "journal": "Nucleic acids research", "date": "2016-12-15", "authors": "Sato Koichi, Shimomuki Mayo, Katsuki Yoko, Takahashi Daisuke, Kobayashi Wataru, Ishiai Masamichi, Miyoshi Hiroyuki, Takata Minoru, Kurumizaka Hitoshi", "evidence": [ { "database": "RefSeq", "id": "NP_001108323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323" } ], "reference": [ { "type": "PubMed", "id": "27694619", "url": "https://glygen.org/publication/PubMed/27694619" } ] }, { "title": "FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.", "journal": "Nature structural & molecular biology", "date": "2020-03", "authors": "Alc\u00f3n Pablo, Shakeel Shabih, Chen Zhuo A, Rappsilber Juri, Patel Ketan J, Passmore Lori A", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" }, { "database": "RefSeq", "id": "NP_001108323", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108323" } ], "reference": [ { "type": "PubMed", "id": "32066963", "url": "https://glygen.org/publication/PubMed/32066963" } ] }, { "title": "The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination.", "journal": "Nature structural & molecular biology", "date": "2022-09", "authors": "Sijacki Tamara, Alc\u00f3n Pablo, Chen Zhuo A, McLaughlin Stephen H, Shakeel Shabih, Rappsilber Juri, Passmore Lori A", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" } ], "reference": [ { "type": "PubMed", "id": "36050501", "url": "https://glygen.org/publication/PubMed/36050501" } ] }, { "title": "FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions.", "journal": "Nature", "date": "2024-08", "authors": "Alc\u00f3n Pablo, Kaczmarczyk Artur P, Ray Korak Kumar, Liolios Themistoklis, Guilbaud Guillaume, Sijacki Tamara, Shen Yichao, McLaughlin Stephen H, Sale Julian E, Knipscheer Puck, Rueda David S, Passmore Lori A", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" } ], "reference": [ { "type": "PubMed", "id": "39085614", "url": "https://glygen.org/publication/PubMed/39085614" } ] } ], "pathway": [ { "id": "gga:415491", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:415491", "resource": "KEGG Pathway" }, { "id": "R-GGA-351465", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465", "resource": "Reactome", "description": "Fanconi Anemia Pathway in DNA repair" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Fanconi anaemia nuclear complex", "id": "GO:0043240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043240", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" } ], "pmid": "" } ] }, { "name": "Biological 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Phosphorylation of FANCI promotes ubiquitination of FANCD2, which prevents DNA release from the FANCI-FANCD2 complex (PubMed:36050501).", "evidence": [ { "database": "UniProtKB", "id": "B0I564", "url": "https://www.uniprot.org/uniprotkb/B0I564" }, { "database": "PubMed", "id": "36050501", "url": "https://glygen.org/publication/PubMed/36050501" } ] } ], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "8a2q", "pdb_chain": "b", "start_pos": 1, "end_pos": 1338, "overlap": "1.0", "method": "Electron_Microscopy", "type": "experimental", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/8a2q.pdb", "url_external": "https://www.rcsb.org/structure/8a2q" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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Promotes accurate and efficient pairing of homologs during meiosis (By similarity). Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing (By similarity). The FANCI-FANCD2 complex binds and scans double-stranded DNA (dsDNA) for DNA damage; this complex stalls at DNA junctions between double-stranded DNA and single-stranded DNA (PubMed:32066963, PubMed:36050501, PubMed:39085614). May participate in S phase and G2 phase checkpoint activation upon DNA damage (By similarity). Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress (By similarity). Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress (By similarity). Promotes BRCA2/FANCD1 loading onto damaged chromatin (By similarity). May also be involved in B-cell immunoglobulin isotype switching (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81#function" }, { "database": "UniProtKB", "id": "Q9BXW9", "url": "https://www.uniprot.org/uniprotkb/Q9BXW9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [ { "start_pos": 400, "end_pos": 400, "sequence_org": "K", "sequence_mut": "E", "comment": "Reduces ubiquitination on FANCD2 and reduces stalling of the FANCI-FANCD2 complex at DNA junctions; when associated with E-404.", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" }, { "database": "PubMed", "id": "39085614", "url": "https://glygen.org/publication/PubMed/39085614" } ] }, { "start_pos": 404, "end_pos": 404, "sequence_org": "K", "sequence_mut": "E", "comment": "Reduces ubiquitination on FANCD2 and reduces stalling of the FANCI-FANCD2 complex at DNA junctions; when associated with E-400.", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" }, { "database": "PubMed", "id": "39085614", "url": "https://glygen.org/publication/PubMed/39085614" } ] }, { "start_pos": 407, "end_pos": 407, "sequence_org": "R", "sequence_mut": "E", "comment": "Reduces ubiquitination on FANCD2 and reduces stalling of the FANCI-FANCD2 complex at DNA junctions; when associated with E-411.", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" }, { "database": "PubMed", "id": "39085614", "url": "https://glygen.org/publication/PubMed/39085614" } ] }, { "start_pos": 411, "end_pos": 411, "sequence_org": "R", "sequence_mut": "E", "comment": "Reduces ubiquitination on FANCD2 and reduces stalling of the FANCI-FANCD2 complex at DNA junctions; when associated with E-407.", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" }, { "database": "PubMed", "id": "39085614", "url": "https://glygen.org/publication/PubMed/39085614" } ] } ], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "FANCD2", "url": "https://www.uniprot.org/uniprotkb/Q68Y81", "locus": { "chromosome": "12", "start_pos": 2941992, "end_pos": 2989525, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010027361", "url": "https://www.ensembl.org/id/ENSGALG00010027361" } ] } } ], "crossref": [ { "id": "Q68Y81", "url": "https://alphafold.ebi.ac.uk/entry/Q68Y81", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11721", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11721", "database": "CDD", "categories": [ "Protein 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[ "3D Structure" ] }, { "id": "PF14631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q68Y81-1", "url": "https://www.uniprot.org/uniprotkb/Q68Y81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSKRKLSKIDAAEESSKTDLQSRCPETKRSRISDKRAPSQGGLENEGVFEELLRTSGIILKVGEGQNEIAVDQTAFQKKLRVALEKHPSYPGVVNEFISGLESHIKDRSQFKNCLLPCTPARTEGSRTLVHSYCESLIKLLLGIKILQPAVVTLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKWLDGLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQQNEVARELSCLLKQGRRLTVPILDALSRLDLDAELLAEVRQSAMTIVPSVKLEDLPVVIKFILHNVKAADAVEVISDLRKSLDLSSCVLPLQLLGSQRKLKSQAQASSSMSQVTTSQNCVKLLFDVIKQAVRFQKDVSEAWIKAIENSTSVSDHKVLDLIVLLLIHSTNSKNRKQTEKVLRSKIRLGCMPEQLMQNAFQNHSMVIKDFFPSILSLAQTFLHSAHPAVVSFGSCMYKQAFAVFDSYCQQEVVCALVTHVCSGNETELDISLDVLTDLVILHPSLLLRYATFVKTILDSMQKLNPCQIRKLFYILSTLAFSQRQEGSYIQDDMHMVIRKWLSSSVPNHKQMGIIGAVTMMGSVALKRNEADGGLLERPELSIECDGQLSTLLDLVGFCCEQTPEVLALYYDELANLIEKQKGNLDLQLLDKFGKSLVEDFPNDFVVDLSPTVDGSFLFPVKSLYNLDEDETQGAIAINLLPLVSQSEPGRVADEMSNSRKRVVSPICLSPCFRLLRLYTGEQNNGSLEEIDALLGCPLYLTDLEVEGKLDSLSKQEREFLCSLLFYALNWFREVVNAFCQQQDAEMKGKVLTRLQNITELQNVLGKCLAATPGYVPPPATFDSEAPEGVPSINAGGPVRKKNGKKRKSDSSKACSAERTQADESSDGNQPDTELSELEKSATEKETGNPLAQLQSYRPYFRELDLEVFSVLHCGLLTKSILDTEMHTEASEVVQLGPAELCFLLDDMCWKLEHVLTPGSTRRVPFLKERGNKDVGFSHLCQRSPKEVAVCVVKLLKPLCNHMENMHNYFQTVIPNQGVVDESGLNIQEYQLMSSCYHQLLLAFRLLFAWSGFSQHENSNLLRSALQVLADRLKPGETEFLPLEELISESFQYLLNFQASIPSFQCAFILTQVLMAISEKPMTGWKREKMASLAKQFLCQSWMKPGGDREKGSHFNSALHTLLCVYLEHTDNILKAIEEISSVGVPELINSAKDGCSSTYPTLSRQTFPVFFRVMMAQLESSVKSIPAGKPSDSGEVQLEKLLKWNIAVRNFHILINLVKVFDSRPVLSICLKYGRLFVEAFLKLAMPLLDHSFKKHRDDVQSLLKTLQLSTRQLHHMCGHSKIHQDLGLTNHVPLLKKSLEQFVYRVKAMLAFNHCQEAFWVGVLKNRDLQGEEILSQASAAPEEDSAEGSEEDTADSAAEEPDGTDSDSGGAGR", "length": 1439, "header": "sp|Q68Y81-1|FACD2_CHICK Isoform 1 of Fanconi anemia group D2 protein OS=Gallus gallus OX=9031 GN=FANCD2 PE=1 SV=1 CANONICAL=Q68Y81-1" }, "isoforms": [ { "isoform_ac": "Q68Y81-1", "url": "https://www.uniprot.org/uniprotkb/Q68Y81/entry#Q68Y81-1", "sequence": { "sequence": "MVSKRKLSKIDAAEESSKTDLQSRCPETKRSRISDKRAPSQGGLENEGVFEELLRTSGIILKVGEGQNEIAVDQTAFQKKLRVALEKHPSYPGVVNEFISGLESHIKDRSQFKNCLLPCTPARTEGSRTLVHSYCESLIKLLLGIKILQPAVVTLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKWLDGLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQQNEVARELSCLLKQGRRLTVPILDALSRLDLDAELLAEVRQSAMTIVPSVKLEDLPVVIKFILHNVKAADAVEVISDLRKSLDLSSCVLPLQLLGSQRKLKSQAQASSSMSQVTTSQNCVKLLFDVIKQAVRFQKDVSEAWIKAIENSTSVSDHKVLDLIVLLLIHSTNSKNRKQTEKVLRSKIRLGCMPEQLMQNAFQNHSMVIKDFFPSILSLAQTFLHSAHPAVVSFGSCMYKQAFAVFDSYCQQEVVCALVTHVCSGNETELDISLDVLTDLVILHPSLLLRYATFVKTILDSMQKLNPCQIRKLFYILSTLAFSQRQEGSYIQDDMHMVIRKWLSSSVPNHKQMGIIGAVTMMGSVALKRNEADGGLLERPELSIECDGQLSTLLDLVGFCCEQTPEVLALYYDELANLIEKQKGNLDLQLLDKFGKSLVEDFPNDFVVDLSPTVDGSFLFPVKSLYNLDEDETQGAIAINLLPLVSQSEPGRVADEMSNSRKRVVSPICLSPCFRLLRLYTGEQNNGSLEEIDALLGCPLYLTDLEVEGKLDSLSKQEREFLCSLLFYALNWFREVVNAFCQQQDAEMKGKVLTRLQNITELQNVLGKCLAATPGYVPPPATFDSEAPEGVPSINAGGPVRKKNGKKRKSDSSKACSAERTQADESSDGNQPDTELSELEKSATEKETGNPLAQLQSYRPYFRELDLEVFSVLHCGLLTKSILDTEMHTEASEVVQLGPAELCFLLDDMCWKLEHVLTPGSTRRVPFLKERGNKDVGFSHLCQRSPKEVAVCVVKLLKPLCNHMENMHNYFQTVIPNQGVVDESGLNIQEYQLMSSCYHQLLLAFRLLFAWSGFSQHENSNLLRSALQVLADRLKPGETEFLPLEELISESFQYLLNFQASIPSFQCAFILTQVLMAISEKPMTGWKREKMASLAKQFLCQSWMKPGGDREKGSHFNSALHTLLCVYLEHTDNILKAIEEISSVGVPELINSAKDGCSSTYPTLSRQTFPVFFRVMMAQLESSVKSIPAGKPSDSGEVQLEKLLKWNIAVRNFHILINLVKVFDSRPVLSICLKYGRLFVEAFLKLAMPLLDHSFKKHRDDVQSLLKTLQLSTRQLHHMCGHSKIHQDLGLTNHVPLLKKSLEQFVYRVKAMLAFNHCQEAFWVGVLKNRDLQGEEILSQASAAPEEDSAEGSEEDTADSAAEEPDGTDSDSGGAGR", "length": 1439, "header": "sp|Q68Y81-1|FACD2_CHICK Isoform 1 of Fanconi anemia group D2 protein OS=Gallus gallus OX=9031 GN=FANCD2 PE=1 SV=1 CANONICAL=Q68Y81-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 835, "start_aa": "Thr", "end_pos": 835, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr835", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.", "journal": "Molecular cell", "date": "2001", "authors": "Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C, Hejna J, Grompe M, D'Andrea AD", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "11239454", "url": "https://glygen.org/publication/PubMed/11239454" } ] }, { "title": "Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways.", "journal": "Cell", "date": "2002", "authors": "Taniguchi T, Garcia-Higuera I, Xu B, Andreassen PR, Gregory RC, Kim ST, Lane WS, Kastan MB, D'Andrea AD", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "12086603", "url": "https://glygen.org/publication/PubMed/12086603" } ] }, { "title": "Insights into DNA recombination from the structure of a RAD51-BRCA2 complex.", "journal": "Nature", "date": "2002", "authors": "Pellegrini L, Yu DS, Lo T, Anand S, Lee M, Blundell TL, Venkitaraman AR", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "12442171", "url": "https://glygen.org/publication/PubMed/12442171" } ] }, { "title": "Fanconi anemia protein FANCD2 promotes immunoglobulin gene conversion and DNA repair through a mechanism related to homologous recombination.", "journal": "Mol. Cell. Biol.", "date": "2005", "authors": "Yamamoto Kazuhiko, Hirano Seiki, Ishiai Masamichi, Morishima Kenichi, Kitao Hiroyuki, Namikoshi Keiko, Kimura Masayo, Matsushita Nobuko, Arakawa Hiroshi, Buerstedde Jean-Marie, Komatsu Kenshi, Thompson Larry H, Takata Minoru", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" } ], "reference": [ { "type": "PubMed", "id": "15601828", "url": "https://glygen.org/publication/PubMed/15601828" } ] }, { "title": "The BRIP1 helicase functions independently of BRCA1 in the Fanconi anemia pathway for DNA crosslink repair.", "journal": "Nature genetics", "date": "2005", "authors": "Bridge WL, Vandenberg CJ, Franklin RJ, Hiom K", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "16116421", "url": "https://glygen.org/publication/PubMed/16116421" } ] }, { "title": "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.", "journal": "Cell", "date": "2007", "authors": "Smogorzewska A, Matsuoka S, Vinciguerra P, McDonald ER 3rd, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K, D'Andrea AD, Elledge SJ", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "17412408", "url": "https://glygen.org/publication/PubMed/17412408" } ] }, { "title": "Identification of the Fanconi anemia complementation group I gene, FANCI.", "journal": "Cellular oncology : the official journal of the International Society for Cellular Oncology", "date": "2007", "authors": "Dorsman JC, Levitus M, Rockx D, Rooimans MA, Oostra AB, Haitjema A, Bakker ST, Steltenpool J, Schuler D, Mohan S, Schindler D, Arwert F, Pals G, Mathew CG, Waisfisz Q, de Winter JP, Joenje H", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "17452773", "url": "https://glygen.org/publication/PubMed/17452773" } ] }, { "title": "FANCI is a second monoubiquitinated member of the Fanconi anemia pathway.", "journal": "Nature structural & molecular biology", "date": "2007", "authors": "Sims AE, Spiteri E, Sims RJ 3rd, Arita AG, Lach FP, Landers T, Wurm M, Freund M, Neveling K, Hanenberg H, Auerbach AD, Huang TT", "evidence": [ { "database": "Reactome", "id": "R-GGA-351465", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465" } ], "reference": [ { "type": "PubMed", "id": "17460694", "url": "https://glygen.org/publication/PubMed/17460694" } ] }, { "title": "FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.", "journal": "Nature structural & molecular biology", "date": "2020-03", "authors": "Alc\u00f3n Pablo, Shakeel Shabih, Chen Zhuo A, Rappsilber Juri, Patel Ketan J, Passmore Lori A", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" } ], "reference": [ { "type": "PubMed", "id": "32066963", "url": "https://glygen.org/publication/PubMed/32066963" } ] }, { "title": "The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination.", "journal": "Nat. Struct. Mol. Biol.", "date": "2022", "authors": "Sijacki Tamara, Alc\u00f3n Pablo, Chen Zhuo A, McLaughlin Stephen H, Shakeel Shabih, Rappsilber Juri, Passmore Lori A", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" } ], "reference": [ { "type": "PubMed", "id": "36050501", "url": "https://glygen.org/publication/PubMed/36050501" } ] }, { "title": "FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions.", "journal": "Nature", "date": "2024-08", "authors": "Alc\u00f3n Pablo, Kaczmarczyk Artur P, Ray Korak Kumar, Liolios Themistoklis, Guilbaud Guillaume, Sijacki Tamara, Shen Yichao, McLaughlin Stephen H, Sale Julian E, Knipscheer Puck, Rueda David S, Passmore Lori A", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" } ], "reference": [ { "type": "PubMed", "id": "39085614", "url": "https://glygen.org/publication/PubMed/39085614" } ] } ], "pathway": [ { "id": "R-GGA-351465", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-GGA-351465", "resource": "Reactome", "description": "Fanconi Anemia Pathway in DNA repair" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [ { "annotation": "Monoubiquitinated on Lys-563 during S phase and upon genotoxic stress (By similarity). Deubiquitinated by USP1 as cells enter G2/M, or once DNA repair is completed (By similarity). Monoubiquitination prevents DNA release from the FANCI-FANCD2 complex (PubMed:32066963). FANCD2 is only ubiquitinated in the FANCI-FANCD2 complex and the monoubiquitination of FANCD2 is promoted by phosphorylation of FANCI (PubMed:32066963).", "evidence": [ { "database": "UniProtKB", "id": "Q68Y81", "url": "https://www.uniprot.org/uniprotkb/Q68Y81" }, { "database": "PubMed", "id": "32066963", "url": "https://glygen.org/publication/PubMed/32066963" } ] } ], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [ { "pdb_id": "6tni", "pdb_chain": "a", "start_pos": 1, "end_pos": 1439, "overlap": "1.0", "method": "Electron_Microscopy", "type": "experimental", "resolution": -1.0, "url": "https://data.glygen.org/ln2downloads/pdb/current/6tni.pdb", "url_external": "https://www.rcsb.org/structure/6tni" } ], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 835 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 373, "end_pos": 375 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 748, "end_pos": 750 }, { "start_pos": 820, "end_pos": 822 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", 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"A0ACD6B774_CHICK", "mass": { "chemical_mass": 24887.0, "monoisotopic_mass": 24887.0 }, "refseq": {}, "gene_names": [ { "name": "PRXL2A", "type": "recommended", "evidence": [ { "id": "A0ACD6B774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B774" } ] } ], "protein_names": [ { "name": "Peroxiredoxin-like 2A", "type": "recommended", "evidence": [ { "id": "A0ACD6B774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B774/entry#names_and_taxonomy" } ] }, { "name": "Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes", "type": "synonym", "evidence": [ { "id": "A0ACD6B774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B774/entry#names_and_taxonomy" } ] }, { "name": "Redox-regulatory protein FAM213A", "type": "synonym", "evidence": [ { "id": "A0ACD6B774", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B774/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": 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"IPR032801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR28630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28630:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28630:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13911", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13911", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "A0ACD6B774", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B774", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ACD6B774-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B774-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFLPDFGIFTMGMWSVGLGAVGAAITGIVLANTDLFLSKPEKATLEFLEAIELKTLGSEPRTFKASELWKKNGAVIMAVRRPGCFLCREEASELSSLKPQLSKLGVPLYAVVKEKIGTEVEDFQHYFQGEIFLDEKRSFYGPRKRKMMLSGFFRIGVWQNFFRAWKNGYSGNLEGEGFTLGGVYVIGAGRQGVLLEHREKEFGDKVSLPSVLEAAEKIKPQAS", "length": 224, "header": "tr|A0ACD6B774-1|A0ACD6B774_CHICK Isoform 1 of Peroxiredoxin-like 2A OS=Gallus gallus OX=9031 GN=PRXL2A PE=1 SV=1 CANONICAL=A0ACD6B774-1" }, "isoforms": [ { "isoform_ac": "A0ACD6B774-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B774/entry#A0ACD6B774-1", "sequence": { "sequence": "MSFLPDFGIFTMGMWSVGLGAVGAAITGIVLANTDLFLSKPEKATLEFLEAIELKTLGSEPRTFKASELWKKNGAVIMAVRRPGCFLCREEASELSSLKPQLSKLGVPLYAVVKEKIGTEVEDFQHYFQGEIFLDEKRSFYGPRKRKMMLSGFFRIGVWQNFFRAWKNGYSGNLEGEGFTLGGVYVIGAGRQGVLLEHREKEFGDKVSLPSVLEAAEKIKPQAS", "length": 224, "header": "tr|A0ACD6B774-1|A0ACD6B774_CHICK Isoform 1 of Peroxiredoxin-like 2A OS=Gallus gallus OX=9031 GN=PRXL2A PE=1 SV=1 CANONICAL=A0ACD6B774-1" }, "locus": { "chromosome": "6", "start_pos": 5073207, "end_pos": 5067383, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010026263.1", "url": "https://www.ensembl.org/id/ENSGALT00010026263.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010014887.1", "url": "https://www.ensembl.org/id/ENSGALP00010014887.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q98TY6-1", "uniprot_ac": "Q98TY6", "uniprot_id": "CBL_CHICK", "mass": { "chemical_mass": 99824.0, "monoisotopic_mass": 99824.0 }, "refseq": {}, "gene_names": [ { "name": "CBL", "type": "recommended", "evidence": [ { "id": "Q98TY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TY6" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase CBL", "type": "recommended", "evidence": [ { "id": "Q98TY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TY6/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "Q98TY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TY6/entry#names_and_taxonomy" } ] }, { "name": "Casitas B-lineage lymphoma protein", "type": "synonym", "evidence": [ { "id": "Q98TY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q98TY6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "(Microbial infection) Targeted by Eimeria acervulina micronemal protein 3, which suppresses apoptosis in chicken duodenal epithelial cells.", "evidence": [ { "database": "UniProtKB", "id": "Q98TY6", "url": "https://www.uniprot.org/uniprotkb/Q98TY6#function" }, { "database": "PubMed", "id": "34141730", "url": "https://glygen.org/publication/PubMed/34141730" } ] }, { "annotation": "E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome (By similarity). Involved in regulation of apoptosis in duodenal epithelial cells (PubMed:34141730).", "evidence": [ { "database": "UniProtKB", "id": "Q98TY6", "url": "https://www.uniprot.org/uniprotkb/Q98TY6#function" }, { "database": "PubMed", "id": "34141730", "url": "https://glygen.org/publication/PubMed/34141730" }, { "database": "UniProtKB", "id": "RU367001", "url": "https://www.uniprot.org/uniprotkb/RU367001#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "Q98TY6", "url": "https://www.uniprot.org/uniprotkb/Q98TY6" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "CBL", "url": "https://www.uniprot.org/uniprotkb/Q98TY6", "locus": { "chromosome": "24", "start_pos": 4282393, "end_pos": 4312897, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010024138", "url": "https://www.ensembl.org/id/ENSGALG00010024138" } ] } } ], "crossref": [ { "id": "Q98TY6", "url": "https://alphafold.ebi.ac.uk/entry/Q98TY6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09920", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09920", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14393", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14393", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16708", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16708", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "374038", "url": "https://www.ncbi.nlm.nih.gov/gene/374038", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036537", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036537", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:374038", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374038", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q98TY6", "url": "https://www.orthodb.org/?gene=Q98TY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23007", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23007", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23007:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23007:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00097", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00097", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02262", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02262", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02761", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02761", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02762", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02762", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "Q98TY6", "url": "https://www.uniprot.org/uniprotkb/Q98TY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q98TY6-1", "url": "https://www.uniprot.org/uniprotkb/Q98TY6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAPLKKGPGGLIGLMKDAFQPHHHHLGPHQPGAVDKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILRTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESEGQGCPFCRCEIKGTEPIVVDPFDPRGGGGLSRQGAEGTPSPNYDDDDDDRADDSLFMMKELAGTKVERPPSPFSVAPQATLPPVPPRLDLLQQRVSNPPGASSPSTSSKAAPGTLHKDKPLPIPPTLRDLPPPPPPDRPHSIGADARPQRRPLPCTPTDCPARDKPPPVPSNRQGDLWPSRPIPKAPSVAHSPGDHWPGRELSNRHSLPFSLPSQMDSRPESHRLGSTLSLDNPVNLNTGPPATSECEHPKIKPSSSANAIYSLAARPLPVPKLPPGEQSESDEDTEYMSPSSLPVVPPGPAVQKPEIKMPLEMTQSLRVLECDRQADGCMYEAMYNIHSQAMPSAFETVNTSDEGDLAAATASNGPEESENEEDGYDVPKPPLPVAIARCTLSDISNATPAFSRMSLENDPVTGFSDGSQVPERPPKPLPRRINSERKAGSCQPGAASSNTGASLQLSSEIENLMSQGYSYQDIQKALVIAHNNIEMAKNILREFVSISSPAHVAT", "length": 903, "header": "sp|Q98TY6-1|CBL_CHICK Isoform 1 of E3 ubiquitin-protein ligase CBL OS=Gallus gallus OX=9031 GN=CBL PE=1 SV=1 CANONICAL=Q98TY6-1" }, "isoforms": [ { "isoform_ac": "Q98TY6-1", "url": "https://www.uniprot.org/uniprotkb/Q98TY6/entry#Q98TY6-1", "sequence": { "sequence": "MSAPLKKGPGGLIGLMKDAFQPHHHHLGPHQPGAVDKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFMENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILRTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESEGQGCPFCRCEIKGTEPIVVDPFDPRGGGGLSRQGAEGTPSPNYDDDDDDRADDSLFMMKELAGTKVERPPSPFSVAPQATLPPVPPRLDLLQQRVSNPPGASSPSTSSKAAPGTLHKDKPLPIPPTLRDLPPPPPPDRPHSIGADARPQRRPLPCTPTDCPARDKPPPVPSNRQGDLWPSRPIPKAPSVAHSPGDHWPGRELSNRHSLPFSLPSQMDSRPESHRLGSTLSLDNPVNLNTGPPATSECEHPKIKPSSSANAIYSLAARPLPVPKLPPGEQSESDEDTEYMSPSSLPVVPPGPAVQKPEIKMPLEMTQSLRVLECDRQADGCMYEAMYNIHSQAMPSAFETVNTSDEGDLAAATASNGPEESENEEDGYDVPKPPLPVAIARCTLSDISNATPAFSRMSLENDPVTGFSDGSQVPERPPKPLPRRINSERKAGSCQPGAASSNTGASLQLSSEIENLMSQGYSYQDIQKALVIAHNNIEMAKNILREFVSISSPAHVAT", "length": 903, "header": "sp|Q98TY6-1|CBL_CHICK Isoform 1 of E3 ubiquitin-protein ligase CBL OS=Gallus gallus OX=9031 GN=CBL PE=1 SV=1 CANONICAL=Q98TY6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 434, "start_aa": "Thr", "end_pos": 434, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr434", "evidence": [ { "id": "GLY_001161", "database": "GlyGen", "url": "https://data.glygen.org/GLY_001161" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Identification of host protein CBL interacting with Eimeria acervulina microneme protein MIC3.", "journal": "Acta Biochim. Biophys. Sin.", "date": "2020", "authors": "Song H., Wang P., Wang Q., Wu H., Zhao H., Cheng C., Gao C.", "evidence": [ { "database": "UniProtKB", "id": "Q98TY6", "url": "https://www.uniprot.org/uniprotkb/Q98TY6" } ], "reference": [ { "type": "PubMed", "id": "32743636", "url": "https://glygen.org/publication/PubMed/32743636" } ] }, { "title": "Eimeria acervulina Microneme Protein 3 Inhibits Apoptosis of the Chicken Duodenal Epithelial Cell by Targeting the Casitas B-Lineage Lymphoma Protein.", "journal": "Frontiers in veterinary science", "date": "2021", "authors": "Wang Pu, Jia Yukun, Han Yue, Wang Weirong, Zhu Yiran, Xu Jiali, Guan Chiyu, Ying Jinpeng, Deng Simin, Wang Jing, Zhang Xian, Chen Mianmian, Cheng Changyong, Song Houhui", "evidence": [ { "database": "UniProtKB", "id": "Q98TY6", "url": "https://www.uniprot.org/uniprotkb/Q98TY6" } ], "reference": [ { "type": "PubMed", "id": "34141730", "url": "https://glygen.org/publication/PubMed/34141730" } ] } ], "pathway": [ { "id": "gga:374038", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?gga:374038", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "phosphotyrosine residue binding", "id": "GO:0001784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001784", "evidence": [ { "database": "UniProtKB", "id": "Q98TY6", "url": "https://www.uniprot.org/uniprotkb/Q98TY6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q98TY6", "url": "https://www.uniprot.org/uniprotkb/Q98TY6" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "Q98TY6", "url": "https://www.uniprot.org/uniprotkb/Q98TY6" } ], "pmid": "" }, { "name": "ephrin receptor binding", "id": "GO:0046875", "url": 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